Guide to the Human Genome
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Search of human proteins with 27262622

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27262622 neuron navigator 1 [Homo sapiens]
         (1874 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27262622 neuron navigator 1 [Homo sapiens]                        3694   0.0  
gi|120953251 neuron navigator 3 [Homo sapiens]                       1264   0.0  
gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]             1201   0.0  
gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]              1201   0.0  
gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]             1196   0.0  
gi|239747580 PREDICTED: similar to NAV1 protein [Homo sapiens]       1134   0.0  
gi|161169017 neuron navigator 2 isoform 4 [Homo sapiens]             1092   0.0  
gi|169218146 PREDICTED: similar to neuron navigator 3, partial [...   664   0.0  
gi|239750047 PREDICTED: similar to neuron navigator 2, partial [...   468   e-131
gi|16975496 cortactin binding protein 2 [Homo sapiens]                106   2e-22
gi|167736355 mucin 4 isoform a [Homo sapiens]                          72   4e-12
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        65   5e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    64   1e-09
gi|163965366 nascent polypeptide-associated complex alpha subuni...    63   3e-09
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        59   3e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    59   6e-08
gi|31324577 molecule interacting with Rab13 [Homo sapiens]             59   6e-08
gi|42476164 POU class 2 homeobox 1 [Homo sapiens]                      58   8e-08
gi|83367077 mucin 16 [Homo sapiens]                                    58   1e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    57   2e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    57   2e-07
gi|91982772 mucin 17 [Homo sapiens]                                    56   3e-07
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       54   1e-06
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    53   2e-06
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ...    53   3e-06
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ...    53   3e-06
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ...    53   3e-06
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ...    53   3e-06
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ...    52   4e-06
gi|30039694 zinc finger protein 598 [Homo sapiens]                     52   4e-06

>gi|27262622 neuron navigator 1 [Homo sapiens]
          Length = 1874

 Score = 3694 bits (9579), Expect = 0.0
 Identities = 1874/1874 (100%), Positives = 1874/1874 (100%)

Query: 1    MLGSSVKSVQPEVELSSGGGDEGADEPRGAGRKAAAADGRGMLPKRAKAPGGGGGMAKAS 60
            MLGSSVKSVQPEVELSSGGGDEGADEPRGAGRKAAAADGRGMLPKRAKAPGGGGGMAKAS
Sbjct: 1    MLGSSVKSVQPEVELSSGGGDEGADEPRGAGRKAAAADGRGMLPKRAKAPGGGGGMAKAS 60

Query: 61   AAELKVFKSGSVDSRVPGGPPASNLRKQKSLTNLSFLTDSEKKLQLYEPEWSDDMAKAPK 120
            AAELKVFKSGSVDSRVPGGPPASNLRKQKSLTNLSFLTDSEKKLQLYEPEWSDDMAKAPK
Sbjct: 61   AAELKVFKSGSVDSRVPGGPPASNLRKQKSLTNLSFLTDSEKKLQLYEPEWSDDMAKAPK 120

Query: 121  GLGKVGSKGREAPLMSKTLSKSEHSLFQAKGSPAGGAKTPLAPLAPNLGKPSRIPRGPYA 180
            GLGKVGSKGREAPLMSKTLSKSEHSLFQAKGSPAGGAKTPLAPLAPNLGKPSRIPRGPYA
Sbjct: 121  GLGKVGSKGREAPLMSKTLSKSEHSLFQAKGSPAGGAKTPLAPLAPNLGKPSRIPRGPYA 180

Query: 181  EVKPLSKAPEAAVSEDGKSDDELLSSKAKAQKSSGPVPSAKGQEERAFLKVDPELVVTVL 240
            EVKPLSKAPEAAVSEDGKSDDELLSSKAKAQKSSGPVPSAKGQEERAFLKVDPELVVTVL
Sbjct: 181  EVKPLSKAPEAAVSEDGKSDDELLSSKAKAQKSSGPVPSAKGQEERAFLKVDPELVVTVL 240

Query: 241  GDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMTCYDSDDAN 300
            GDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMTCYDSDDAN
Sbjct: 241  GDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMTCYDSDDAN 300

Query: 301  PRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPM 360
            PRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPM
Sbjct: 301  PRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPM 360

Query: 361  RSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDDITTGWDESSSISSGL 420
            RSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDDITTGWDESSSISSGL
Sbjct: 361  RSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDDITTGWDESSSISSGL 420

Query: 421  SDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKA 480
            SDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKA
Sbjct: 421  SDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKA 480

Query: 481  PKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVT 540
            PKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVT
Sbjct: 481  PKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVT 540

Query: 541  SPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPS 600
            SPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPS
Sbjct: 541  SPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPS 600

Query: 601  TSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFL 660
            TSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFL
Sbjct: 601  TSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFL 660

Query: 661  APGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTK 720
            APGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTK
Sbjct: 661  APGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTK 720

Query: 721  VASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAEL 780
            VASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAEL
Sbjct: 721  VASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAEL 780

Query: 781  PPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSC 840
            PPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSC
Sbjct: 781  PPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSC 840

Query: 841  FTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPS 900
            FTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPS
Sbjct: 841  FTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPS 900

Query: 901  STPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKE 960
            STPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKE
Sbjct: 901  STPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKE 960

Query: 961  RRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEA 1020
            RRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEA
Sbjct: 961  RRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEA 1020

Query: 1021 AFELYSGSQMGSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQS 1080
            AFELYSGSQMGSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQS
Sbjct: 1021 AFELYSGSQMGSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQS 1080

Query: 1081 EQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELL 1140
            EQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELL
Sbjct: 1081 EQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELL 1140

Query: 1141 DLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSS 1200
            DLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSS
Sbjct: 1141 DLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSS 1200

Query: 1201 KDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTET 1260
            KDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTET
Sbjct: 1201 KDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTET 1260

Query: 1261 ASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEKEMKLTD 1320
            ASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEKEMKLTD
Sbjct: 1261 ASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEKEMKLTD 1320

Query: 1321 IRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGSSALSSP 1380
            IRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGSSALSSP
Sbjct: 1321 IRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGSSALSSP 1380

Query: 1381 RRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVTLRVVVRMPPQHIIKGDLKQQEFF 1440
            RRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVTLRVVVRMPPQHIIKGDLKQQEFF
Sbjct: 1381 RRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVTLRVVVRMPPQHIIKGDLKQQEFF 1440

Query: 1441 LGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKRVLDAEPP 1500
            LGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKRVLDAEPP
Sbjct: 1441 LGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKRVLDAEPP 1500

Query: 1501 EMPPCRRGVNNISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTG 1560
            EMPPCRRGVNNISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTG
Sbjct: 1501 EMPPCRRGVNNISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTG 1560

Query: 1561 KTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPL 1620
            KTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPL
Sbjct: 1561 KTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPL 1620

Query: 1621 VILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNV 1680
            VILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNV
Sbjct: 1621 VILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNV 1680

Query: 1681 EPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPC 1740
            EPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPC
Sbjct: 1681 EPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPC 1740

Query: 1741 FFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDTLPWPS 1800
            FFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDTLPWPS
Sbjct: 1741 FFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDTLPWPS 1800

Query: 1801 AQQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLLKLQEAANYIESP 1860
            AQQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLLKLQEAANYIESP
Sbjct: 1801 AQQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLLKLQEAANYIESP 1860

Query: 1861 DRETILDPNLQATL 1874
            DRETILDPNLQATL
Sbjct: 1861 DRETILDPNLQATL 1874


>gi|120953251 neuron navigator 3 [Homo sapiens]
          Length = 2363

 Score = 1264 bits (3270), Expect = 0.0
 Identities = 786/1903 (41%), Positives = 1106/1903 (58%), Gaps = 198/1903 (10%)

Query: 113  DDMAKAPKGLGKVGSKG---REAPLMSKTLSKSEHSLFQAKGSPAGGAKTPLAPLAPNLG 169
            + +  +  G+ K GSK    ++      T SK        KGSP+     P+     +  
Sbjct: 518  ESLIPSSSGIPKPGSKVPTVKQTISPGSTASKESEKFRTTKGSPSQSLSKPITMEKASAS 577

Query: 170  K-PSRIPRGPYAEVKPLSKAPEAAVSEDGKSDDELLSSKAKAQKSSGP--------VPSA 220
              P+ +      +  P            G+S         + Q+ S P        +  A
Sbjct: 578  SCPAPLEGREAGQASPSGSCTMTVAQSSGQSTGNGAVQLPQQQQHSHPNTATVAPFIYRA 637

Query: 221  KGQEERAFL----------KVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQ 270
              + E   L          K+D     T    LE++      DPE++R RTV+N+ DLRQ
Sbjct: 638  HSENEGTALPSADSCTSPTKMDLSYSKTAKQCLEEISGE---DPETRRMRTVKNIADLRQ 694

Query: 271  NLEETMSSLRGSQVTHSSLEMTCYDSD---DANPRSVSSLSNRSSPLSWRYGQSSPRLQA 327
            NLEETMSSLRG+Q++HS+LE T +DS    + N R++ +L++R +P++WR GQ+ PRLQA
Sbjct: 695  NLEETMSSLRGTQISHSTLETT-FDSTVTTEVNGRTIPNLTSRPTPMTWRLGQACPRLQA 753

Query: 328  GDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPMR--SPSKLSHISRLELVESLDSD---- 381
            GDAPS+G      GT   ++H + + + +T P+R  + S+L ++S++++ E   SD    
Sbjct: 754  GDAPSLGAGYPRSGTSR-FIHTDPSRFMYTTPLRRAAVSRLGNMSQIDMSEKASSDLDMS 812

Query: 382  -EVDLKSGYMSDSDLMGKTMTEDD------------------------------------ 404
             EVD+  GYMSD D++GK++  DD                                    
Sbjct: 813  SEVDV-GGYMSDGDILGKSLRTDDINSGYMTDGGLNLYTRSLNRIPDTATSRDIIQRGVH 871

Query: 405  DITT---GWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSE 461
            D+T     WD+SSS+SSGLSD  DN+S+++ N +SS++S  +    SR+N+   LRTDSE
Sbjct: 872  DVTVDADSWDDSSSVSSGLSDTLDNISTDDLNTTSSVSSYSNITVPSRKNTQ--LRTDSE 929

Query: 462  KRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPI 521
            KRS  +   +W S  E K P++ ++DS          KW+       +D  K G+ K  +
Sbjct: 930  KRSTTDE--TWDSPEELKKPEE-DFDSHG----DAGGKWKTVSSGLPEDPEKAGQ-KASL 981

Query: 522  SLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPE-GKATDKGKLAVKNTGLQRSSSD 580
            S+   GS ++G +      S       SALK  GK +  KA++KGK  +K + LQRS SD
Sbjct: 982  SVSQTGSWRRGMSAQGGAPSR-QKAGTSALKTPGKTDDAKASEKGKAPLKGSSLQRSPSD 1040

Query: 581  AGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTG-----GSATLSKIQKSS 635
            AG+    + KKPPSGI R + + SFG+KKP     +A +  +G     GSATL KI KS+
Sbjct: 1041 AGKSSGDEGKKPPSGIGRSTATSSFGFKKPSGVGSSAMITSSGATITSGSATLGKIPKSA 1100

Query: 636  GIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVS 695
             I  K   GRKTSLD S + +   L   +++ +QYRSLPRP+KSS+  + G RGG R  +
Sbjct: 1101 AIGGKSNAGRKTSLDGSQNQDDVVLHVSSKTTLQYRSLPRPSKSSTSGIPG-RGGHRSST 1159

Query: 696  SSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISL 755
            SSID S +S+K  G T S+L+EPTK+ SGR++P  VNQTD+EKEK        DS+++SL
Sbjct: 1160 SSID-SNVSSKSAGATTSKLREPTKIGSGRSSPVTVNQTDKEKEKVAVS----DSESVSL 1214

Query: 756  KSIGSPESTPKN------QASHPTATKLAELPPTPLRAT--AKSFVKPPSLANLDKVNSN 807
               GSP+S+P +      Q      +K  ++     R    AK+  K  S  N + V S+
Sbjct: 1215 S--GSPKSSPTSASACGAQGLRQPGSKYPDIASPTFRRLFGAKAGGKSASAPNTEGVKSS 1272

Query: 808  SLDLPSSSDTTHAS---KVPDLHATSSASGGPLPSCFTP--------------------- 843
            S+ +PS S T       + P     S  S G L    +P                     
Sbjct: 1273 SV-MPSPSTTLARQGSLESPSSGTGSMGSAGGLSGSSSPLFNKPSDLTTDVISLSHSLAS 1331

Query: 844  SPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTP 903
            SPA + +  S        + S  +  K+T  Y  ++ LH S ES+ +P+S   +    T 
Sbjct: 1332 SPASVHSFTSGGLVWAANMSSSSAGSKDTPSYQSMTSLHTSSESIDLPLSHHGSLSGLT- 1390

Query: 904  VPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQS----QEETK 959
                       T E    L  +GS R+   +S Q DRNTLPKKGLRY   S    QEE K
Sbjct: 1391 ---------TGTHEVQSLLMRTGSVRSTLSESMQLDRNTLPKKGLRYTPSSRQANQEEGK 1441

Query: 960  ERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSPTAATT-----PRITRSNS 1014
            E   SH+ GGL ++ +QS L SP A+  S + K   +N+VSPT  +      P + RSNS
Sbjct: 1442 EWLRSHSTGGLQDTGNQSPLVSPSAMSSSAAGKYHFSNLVSPTNLSQFNLPGPSMMRSNS 1501

Query: 1015 IPTHEAAFELYSGSQM-GSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSS 1073
            IP  +++F+LY  SQ+ GS  SL ERP+ +  SGSFRD  ++VHGS LSL SS SS YS+
Sbjct: 1502 IPAQDSSFDLYDDSQLCGSATSLEERPRAISHSGSFRDSMEEVHGSSLSLVSSTSSLYST 1561

Query: 1074 AEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAE 1133
            AEE+  SEQI KLRREL +SQEKVATLTSQLSANA+LVAAFE+SL NMT RL+ L  TAE
Sbjct: 1562 AEEKAHSEQIHKLRRELVASQEKVATLTSQLSANAHLVAAFEKSLGNMTGRLQSLTMTAE 1621

Query: 1134 EKDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITS 1193
            +K++EL++LRETI+ LK +NS AQA IQGALN  +  PK+LRI+RQ+SS+S+SS+NS TS
Sbjct: 1622 QKESELIELRETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATS 1681

Query: 1194 HSSIGSSKDADAKKKKKKSW-------LRSSFNKAFSIKKGPKSASSYSDIEEIATPDSS 1246
            HSSIGS  DAD+KKKKKK+W       LRSSF +AF  KK  K  SS+SDIEE+   DSS
Sbjct: 1682 HSSIGSGNDADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELT--DSS 1739

Query: 1247 APSSPKLQHGSTETASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSE 1306
             P+SPKL H + +  S S+K S S+S   + TE                    E + + +
Sbjct: 1740 LPASPKLPHNAGDCGSASMKPSQSASAICECTEA-------------------EAEIILQ 1780

Query: 1307 LRSELWEKEMKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGS 1366
            L+SEL EKE+KLTDIRLEAL+SAH LDQ+RE M+ MQ E+++LKAENDRLK   G ++  
Sbjct: 1781 LKSELREKELKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTAKP 1840

Query: 1367 T--PGQVPGSSALSSPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVTLRVVVRM 1424
            T  P +   S++ SS R+SLGL+L +        +D+   D     G K+  +++++V +
Sbjct: 1841 TRPPSESSSSTSSSSSRQSLGLSLNNLNITEAVSSDILLDDAGDATGHKDGRSVKIIVSI 1900

Query: 1425 PPQHIIKGDLKQQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIH 1484
               +    D K Q + +G   VSGK  W +LD  + ++FK+Y+ ++D +++LGLS++ I 
Sbjct: 1901 SKGYGRAKDQKSQAYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRIDTSTSLGLSSDCIA 1960

Query: 1485 GYSISHVKRVLDAEPPEMPPCRR--GVNNI-SVSLKGLKEKCVDSLVFETLIPKPMMQHY 1541
             Y I  + R  + E PE+ PC    G NNI +V+LKG++E  +DS VF+TLIPKP+ Q Y
Sbjct: 1961 SYCIGDLIRSHNLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRY 2020

Query: 1542 ISLLLKHRRLVLSGPSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLY 1601
             +LL++H R++LSGPSGTGKTYL N+LAEY++ +SGR+ TE  ++TFN+  +S K+LQ Y
Sbjct: 2021 FNLLMEHHRIILSGPSGTGKTYLANKLAEYVITKSGRKKTEDAIATFNVDHKSSKELQQY 2080

Query: 1602 LSNLANQIDRETGIGDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKM 1661
            L+NLA Q   +    ++P+VI+LD+L   GS+S++ NG L CKY+KCPYIIGT NQ V  
Sbjct: 2081 LANLAEQCSADNNGVELPVVIILDNLHHVGSLSDIFNGFLNCKYNKCPYIIGTMNQGVSS 2140

Query: 1662 TPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWY 1721
            +PN  LH +FR +  +N+ EP  GFL RYLRRKL+E + + N    +L++++DW+PK W+
Sbjct: 2141 SPNLELHHNFRWVLCANHTEPVKGFLGRYLRRKLIEIEIERNIRNNDLVKIIDWIPKTWH 2200

Query: 1722 HLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQ 1781
            HL++FLE HS+SD  IGP  FL CP+ +E  R WF+DLWN S++PY+ E  ++G++++G+
Sbjct: 2201 HLNSFLETHSSSDVTIGPRLFLPCPMDVEGSRVWFMDLWNYSLVPYILEAVREGLQMYGK 2260

Query: 1782 KAAWEDPVEWVRDTLPWPSA--QQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLD 1839
            +  WEDP +WV DT PW SA   Q+   L  L P  VG  S  S  E  T K    +  +
Sbjct: 2261 RTPWEDPSKWVLDTYPWSSATLPQESPALLQLRPEDVGYESCTSTKEATTSKHIPQTDTE 2320

Query: 1840 SDPLMAMLLKLQEAANYIESPD--------RETILDPNLQATL 1874
             DPLM ML+KLQEAANY  +           E ILD +L++TL
Sbjct: 2321 GDPLMNMLMKLQEAANYSSTQSCDSESTSHHEDILDSSLESTL 2363


>gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]
          Length = 2365

 Score = 1201 bits (3107), Expect = 0.0
 Identities = 746/1761 (42%), Positives = 1051/1761 (59%), Gaps = 188/1761 (10%)

Query: 253  DPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMTCYDSD---DANPRSVSSLSN 309
            DPE++R RTV+N+ DLRQNLEETMSSLRG+QVTHS+LE T +D++   + + RS+ SL+ 
Sbjct: 654  DPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETT-FDTNVTTEMSGRSILSLTG 712

Query: 310  RSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPMRSP--SKLS 367
            R +PLSWR GQSSPRLQAGDAPS+G         + +++ E   Y ++ P+R    S+ S
Sbjct: 713  RPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGS 772

Query: 368  HISRLELVESLDSDEVDLKS------GYMSDSDLMGKTMTEDDDITTG------------ 409
             +  +++ +    DE+DL+       GYMSD D++ K +   DDIT+G            
Sbjct: 773  SVCHVDVSDKA-GDEMDLEGISMDAPGYMSDGDVLSKNI-RTDDITSGYMTDGGLGLYTR 830

Query: 410  -----------------------------WDESSSISSGLSDASDNLSSEEFNASSSLNS 440
                                         WD+SSS+SSG+SD  DNLS+++ N SSS++S
Sbjct: 831  RLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISS 890

Query: 441  LPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAPKKLEYDSGS---LKMEPGT 497
              +TP +SR+N  +  +TD+EK S  E    W  +  +K+      D GS   +KMEPG 
Sbjct: 891  YANTPASSRKNLDV--QTDAEKHSQVERNSLWSGDDVKKS------DGGSDSGIKMEPG- 941

Query: 498  SKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQ--SALKVAG 555
            SKWRR   +  D+S K    KK   +   GS ++G T  V +T P T  +    ALK  G
Sbjct: 942  SKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPG 1001

Query: 556  K---PEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKP-PSGIARPSTSG-SFGYKKP 610
                 + K ++KG+L+ K + ++RS SDAGR    ++KKP PS    P+ +  SFG+KK 
Sbjct: 1002 TGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQ 1061

Query: 611  P-PATGTATVMQTG-----GSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGA 664
               A G A +  +G      SATL KI KSS + V    GRK+S+D + + + G+LA  +
Sbjct: 1062 SGSAAGLAMITASGVTVTSRSATLGKIPKSSAL-VSRSAGRKSSMDGAQNQDDGYLALSS 1120

Query: 665  RSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASG 724
            R+N+QYRSLPRP+KS+S +  G R      +SSID S +S+K  GL   +L+EP+K A G
Sbjct: 1121 RTNLQYRSLPRPSKSNSRNGAGNRSS----TSSID-SNISSKSAGLPVPKLREPSKTALG 1175

Query: 725  RTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTP 784
             + P  VNQTD+EK  +         +++ +     P S+P   +  P A       PT 
Sbjct: 1176 SSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTL 1235

Query: 785  LR------------ATAKSFVKPPSLAN--LDKVNSNSLDLPSSSDTTHASKVPDLHATS 830
             R            ATA++      ++N         +LD PS S    +     L++ +
Sbjct: 1236 RRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKN 1295

Query: 831  -SASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQ 889
               +  PL S    SP+   +  S S + G    S  +V K+   +  +S LH S ES+ 
Sbjct: 1296 VDLNQSPLAS----SPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESID 1351

Query: 890  MPMS---LPSAFPSSTPVPTPPAPPAAP-TEEETEELTWSGSPRAG-------------- 931
            + +S   +PS   S+  + +       P     + + T S SP +               
Sbjct: 1352 ISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPR 1411

Query: 932  QLDSNQR-DRNTLPKKGLRY----QLQSQEETKERRHSHTIGGLPESDDQSELPSPPALP 986
            + DS+   DRNTLPKKGLRY    QL++QE+ KE   SH+ GGL ++   S   S  ++ 
Sbjct: 1412 KQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVT 1471

Query: 987  MSLSAKGQLTNIVSPTAAT-----TPRITRSNSIPTHEAAFELYSGSQM-GSTLSLAERP 1040
                 +   + + SPT  T      P + R++S+   +  ++ Y+ S+   S++SL E+ 
Sbjct: 1472 SPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKS 1531

Query: 1041 KGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATL 1100
            + M RSGSFRD  ++VHGS LSL SS SS YS+ EE+ QSE IRKLRREL++SQEKV+ L
Sbjct: 1532 RTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSE-IRKLRRELDASQEKVSAL 1590

Query: 1101 TSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVI 1160
            T+QL+ANA+LVAAFEQSL NMT RL+ L  TAE+KD+EL +LR+TI+ LKK+N+ AQA I
Sbjct: 1591 TTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAI 1650

Query: 1161 QGALNASETTPK--------ELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKS 1212
             G +N  E   K        +LRI+RQ+SSDS+SS+NS TSHSS+GS+ ++D+KKKK+K+
Sbjct: 1651 NGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKN 1710

Query: 1213 WLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSS 1272
            WLRSSF +AF  KK PKSASS+SDIEE+   DSS PSSPKL H  +  ++P +++S S+S
Sbjct: 1711 WLRSSFKQAFGKKKSPKSASSHSDIEEMT--DSSLPSSPKLPHNGSTGSTPLLRNSHSNS 1768

Query: 1273 VGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQL 1332
            +                    +E  + E + V +LR+EL +KEMKLTDIRLEAL+SAHQL
Sbjct: 1769 L-------------------ISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQL 1809

Query: 1333 DQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGSSALS-SPRRSLGLALTHS 1391
            DQLRE M+ MQ E++ LKAENDRLK     S GS   + P   ++S SPR+S+GL+  HS
Sbjct: 1810 DQLREAMNRMQSEIEKLKAENDRLK---SESQGSGCSRAPSQVSISASPRQSMGLS-QHS 1865

Query: 1392 FGPSLADTDLSPMDGISTCGPKEEVT--LRVVVRMPPQHIIKGDLKQQEFFLGCSKVSGK 1449
               + + +    +D    C  ++E    +++VV    +   K D +   F +GC  VSGK
Sbjct: 1866 LNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGK 1925

Query: 1450 VDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKRVLDAEPPEMPPCRRGV 1509
              W +LD  V ++FK+YI  +DP S LGL+++S+ GYSI  +KR   +E PE+ PC   V
Sbjct: 1926 TKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLV 1985

Query: 1510 NN---ISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTGKTYLTN 1566
                 ISV++KGL E  +DSLVFE+LIPKP++Q Y+SLL++HRR++LSGPSGTGKTYL N
Sbjct: 1986 GENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLAN 2045

Query: 1567 RLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPLVILLDD 1626
            RL+EY+V R GRE+T+G+++TFN+  +S K+L+ YLSNLA+Q + E    D+PLVI+LD+
Sbjct: 2046 RLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDN 2105

Query: 1627 LSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGF 1686
            L    S+ E+ NG L CKYHKCPYIIGT NQ    TPN  LH +FR +  +N+ EP  GF
Sbjct: 2106 LHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGF 2165

Query: 1687 LVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCP 1746
            L R+LRRKL+E++        EL++++DW+PK+W+HL+ FLE HS+SD  IGP  FLSCP
Sbjct: 2166 LGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCP 2225

Query: 1747 IGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDTLPWPSA--QQD 1804
            I ++  R WF DLWN SIIPYL E  ++G++++G++A WEDP +WV DT PW ++  Q +
Sbjct: 2226 IDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHE 2285

Query: 1805 QSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLLKLQEAANYIESPD--- 1861
               L  L P  VG    + P E  T K   PS  + DPLM ML++LQEAANY  SP    
Sbjct: 2286 WPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANY-SSPQSYD 2344

Query: 1862 --------RETILDPNLQATL 1874
                     + ILD +L++TL
Sbjct: 2345 SDSNSNSHHDDILDSSLESTL 2365



 Score = 40.8 bits (94), Expect = 0.013
 Identities = 91/433 (21%), Positives = 156/433 (36%), Gaps = 92/433 (21%)

Query: 898  FPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLD--------------SNQRDRNTL 943
            +  S PV +PP PP++    E E L  S S   G  D              +N    + +
Sbjct: 228  YDKSKPVTSPPPPPSS---HEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAI 284

Query: 944  PKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSP--------PALPMSLSAKGQL 995
            P+ G   +   + ++   +HS T+  L       E P P        P    S+  K +L
Sbjct: 285  PQPGAATK-PWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKL 343

Query: 996  TNIVSPTAATTPRITRSNS------IPTHEAAFELYSGSQMGSTLSLA-ERPKGMIRSGS 1048
             N    + A     +R  S      +P+ E + EL + S+M +T+  A   PK       
Sbjct: 344  FNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSSPK------- 396

Query: 1049 FRDPTDDVHGSVLSLASSASSTYSSA----EERMQSEQIRKLRRELESSQEKVATLTSQL 1104
                        ++L   A  T+S A    +  ++  +  K +++ E  +EK   L  + 
Sbjct: 397  ------------IALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRA 444

Query: 1105 SANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQ--G 1162
            S               +T RL    E  E+           +  + KK+S+  + I   G
Sbjct: 445  S---------------VTERLDLKEEPKEDPS------GAAVPEMPKKSSKIASFIPKGG 483

Query: 1163 ALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLRSSFNKAF 1222
             LN++         K++  + S S +      S  G S  A A  K+ +       +   
Sbjct: 484  KLNSA---------KKEPMAPSHSGIPKPGMKSMPGKSPSAPAPSKEGERSRSGKLSSGL 534

Query: 1223 SIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHG-STETASPSIKSSTSSSVGTDVTEGP 1281
              +K        S    +A+ +   P    L H  S++T S S+   T+ + G++ T   
Sbjct: 535  PQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSV--GTTQTTGSN-TVSV 591

Query: 1282 AHPAPHTRLFHAN 1294
              P P  +  H N
Sbjct: 592  QLPQPQQQYNHPN 604


>gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]
          Length = 2429

 Score = 1201 bits (3107), Expect = 0.0
 Identities = 746/1761 (42%), Positives = 1051/1761 (59%), Gaps = 188/1761 (10%)

Query: 253  DPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMTCYDSD---DANPRSVSSLSN 309
            DPE++R RTV+N+ DLRQNLEETMSSLRG+QVTHS+LE T +D++   + + RS+ SL+ 
Sbjct: 718  DPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETT-FDTNVTTEMSGRSILSLTG 776

Query: 310  RSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPMRSP--SKLS 367
            R +PLSWR GQSSPRLQAGDAPS+G         + +++ E   Y ++ P+R    S+ S
Sbjct: 777  RPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGS 836

Query: 368  HISRLELVESLDSDEVDLKS------GYMSDSDLMGKTMTEDDDITTG------------ 409
             +  +++ +    DE+DL+       GYMSD D++ K +   DDIT+G            
Sbjct: 837  SVCHVDVSDKA-GDEMDLEGISMDAPGYMSDGDVLSKNI-RTDDITSGYMTDGGLGLYTR 894

Query: 410  -----------------------------WDESSSISSGLSDASDNLSSEEFNASSSLNS 440
                                         WD+SSS+SSG+SD  DNLS+++ N SSS++S
Sbjct: 895  RLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISS 954

Query: 441  LPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAPKKLEYDSGS---LKMEPGT 497
              +TP +SR+N  +  +TD+EK S  E    W  +  +K+      D GS   +KMEPG 
Sbjct: 955  YANTPASSRKNLDV--QTDAEKHSQVERNSLWSGDDVKKS------DGGSDSGIKMEPG- 1005

Query: 498  SKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQ--SALKVAG 555
            SKWRR   +  D+S K    KK   +   GS ++G T  V +T P T  +    ALK  G
Sbjct: 1006 SKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPG 1065

Query: 556  K---PEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKP-PSGIARPSTSG-SFGYKKP 610
                 + K ++KG+L+ K + ++RS SDAGR    ++KKP PS    P+ +  SFG+KK 
Sbjct: 1066 TGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQ 1125

Query: 611  P-PATGTATVMQTG-----GSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGA 664
               A G A +  +G      SATL KI KSS + V    GRK+S+D + + + G+LA  +
Sbjct: 1126 SGSAAGLAMITASGVTVTSRSATLGKIPKSSAL-VSRSAGRKSSMDGAQNQDDGYLALSS 1184

Query: 665  RSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASG 724
            R+N+QYRSLPRP+KS+S +  G R      +SSID S +S+K  GL   +L+EP+K A G
Sbjct: 1185 RTNLQYRSLPRPSKSNSRNGAGNRSS----TSSID-SNISSKSAGLPVPKLREPSKTALG 1239

Query: 725  RTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTP 784
             + P  VNQTD+EK  +         +++ +     P S+P   +  P A       PT 
Sbjct: 1240 SSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTL 1299

Query: 785  LR------------ATAKSFVKPPSLAN--LDKVNSNSLDLPSSSDTTHASKVPDLHATS 830
             R            ATA++      ++N         +LD PS S    +     L++ +
Sbjct: 1300 RRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKN 1359

Query: 831  -SASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQ 889
               +  PL S    SP+   +  S S + G    S  +V K+   +  +S LH S ES+ 
Sbjct: 1360 VDLNQSPLAS----SPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESID 1415

Query: 890  MPMS---LPSAFPSSTPVPTPPAPPAAP-TEEETEELTWSGSPRAG-------------- 931
            + +S   +PS   S+  + +       P     + + T S SP +               
Sbjct: 1416 ISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPR 1475

Query: 932  QLDSNQR-DRNTLPKKGLRY----QLQSQEETKERRHSHTIGGLPESDDQSELPSPPALP 986
            + DS+   DRNTLPKKGLRY    QL++QE+ KE   SH+ GGL ++   S   S  ++ 
Sbjct: 1476 KQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVT 1535

Query: 987  MSLSAKGQLTNIVSPTAAT-----TPRITRSNSIPTHEAAFELYSGSQM-GSTLSLAERP 1040
                 +   + + SPT  T      P + R++S+   +  ++ Y+ S+   S++SL E+ 
Sbjct: 1536 SPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKS 1595

Query: 1041 KGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATL 1100
            + M RSGSFRD  ++VHGS LSL SS SS YS+ EE+ QSE IRKLRREL++SQEKV+ L
Sbjct: 1596 RTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSE-IRKLRRELDASQEKVSAL 1654

Query: 1101 TSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVI 1160
            T+QL+ANA+LVAAFEQSL NMT RL+ L  TAE+KD+EL +LR+TI+ LKK+N+ AQA I
Sbjct: 1655 TTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAI 1714

Query: 1161 QGALNASETTPK--------ELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKS 1212
             G +N  E   K        +LRI+RQ+SSDS+SS+NS TSHSS+GS+ ++D+KKKK+K+
Sbjct: 1715 NGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKN 1774

Query: 1213 WLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSS 1272
            WLRSSF +AF  KK PKSASS+SDIEE+   DSS PSSPKL H  +  ++P +++S S+S
Sbjct: 1775 WLRSSFKQAFGKKKSPKSASSHSDIEEMT--DSSLPSSPKLPHNGSTGSTPLLRNSHSNS 1832

Query: 1273 VGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQL 1332
            +                    +E  + E + V +LR+EL +KEMKLTDIRLEAL+SAHQL
Sbjct: 1833 L-------------------ISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQL 1873

Query: 1333 DQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGSSALS-SPRRSLGLALTHS 1391
            DQLRE M+ MQ E++ LKAENDRLK     S GS   + P   ++S SPR+S+GL+  HS
Sbjct: 1874 DQLREAMNRMQSEIEKLKAENDRLK---SESQGSGCSRAPSQVSISASPRQSMGLS-QHS 1929

Query: 1392 FGPSLADTDLSPMDGISTCGPKEEVT--LRVVVRMPPQHIIKGDLKQQEFFLGCSKVSGK 1449
               + + +    +D    C  ++E    +++VV    +   K D +   F +GC  VSGK
Sbjct: 1930 LNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGK 1989

Query: 1450 VDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKRVLDAEPPEMPPCRRGV 1509
              W +LD  V ++FK+YI  +DP S LGL+++S+ GYSI  +KR   +E PE+ PC   V
Sbjct: 1990 TKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLV 2049

Query: 1510 NN---ISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTGKTYLTN 1566
                 ISV++KGL E  +DSLVFE+LIPKP++Q Y+SLL++HRR++LSGPSGTGKTYL N
Sbjct: 2050 GENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLAN 2109

Query: 1567 RLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPLVILLDD 1626
            RL+EY+V R GRE+T+G+++TFN+  +S K+L+ YLSNLA+Q + E    D+PLVI+LD+
Sbjct: 2110 RLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDN 2169

Query: 1627 LSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGF 1686
            L    S+ E+ NG L CKYHKCPYIIGT NQ    TPN  LH +FR +  +N+ EP  GF
Sbjct: 2170 LHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGF 2229

Query: 1687 LVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCP 1746
            L R+LRRKL+E++        EL++++DW+PK+W+HL+ FLE HS+SD  IGP  FLSCP
Sbjct: 2230 LGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCP 2289

Query: 1747 IGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDTLPWPSA--QQD 1804
            I ++  R WF DLWN SIIPYL E  ++G++++G++A WEDP +WV DT PW ++  Q +
Sbjct: 2290 IDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHE 2349

Query: 1805 QSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLLKLQEAANYIESPD--- 1861
               L  L P  VG    + P E  T K   PS  + DPLM ML++LQEAANY  SP    
Sbjct: 2350 WPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANY-SSPQSYD 2408

Query: 1862 --------RETILDPNLQATL 1874
                     + ILD +L++TL
Sbjct: 2409 SDSNSNSHHDDILDSSLESTL 2429



 Score = 40.8 bits (94), Expect = 0.013
 Identities = 91/433 (21%), Positives = 156/433 (36%), Gaps = 92/433 (21%)

Query: 898  FPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLD--------------SNQRDRNTL 943
            +  S PV +PP PP++    E E L  S S   G  D              +N    + +
Sbjct: 292  YDKSKPVTSPPPPPSS---HEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAI 348

Query: 944  PKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSP--------PALPMSLSAKGQL 995
            P+ G   +   + ++   +HS T+  L       E P P        P    S+  K +L
Sbjct: 349  PQPGAATK-PWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKL 407

Query: 996  TNIVSPTAATTPRITRSNS------IPTHEAAFELYSGSQMGSTLSLA-ERPKGMIRSGS 1048
             N    + A     +R  S      +P+ E + EL + S+M +T+  A   PK       
Sbjct: 408  FNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSSPK------- 460

Query: 1049 FRDPTDDVHGSVLSLASSASSTYSSA----EERMQSEQIRKLRRELESSQEKVATLTSQL 1104
                        ++L   A  T+S A    +  ++  +  K +++ E  +EK   L  + 
Sbjct: 461  ------------IALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRA 508

Query: 1105 SANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQ--G 1162
            S               +T RL    E  E+           +  + KK+S+  + I   G
Sbjct: 509  S---------------VTERLDLKEEPKEDPS------GAAVPEMPKKSSKIASFIPKGG 547

Query: 1163 ALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLRSSFNKAF 1222
             LN++         K++  + S S +      S  G S  A A  K+ +       +   
Sbjct: 548  KLNSA---------KKEPMAPSHSGIPKPGMKSMPGKSPSAPAPSKEGERSRSGKLSSGL 598

Query: 1223 SIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHG-STETASPSIKSSTSSSVGTDVTEGP 1281
              +K        S    +A+ +   P    L H  S++T S S+   T+ + G++ T   
Sbjct: 599  PQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSV--GTTQTTGSN-TVSV 655

Query: 1282 AHPAPHTRLFHAN 1294
              P P  +  H N
Sbjct: 656  QLPQPQQQYNHPN 668


>gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]
          Length = 2432

 Score = 1196 bits (3093), Expect = 0.0
 Identities = 746/1764 (42%), Positives = 1051/1764 (59%), Gaps = 191/1764 (10%)

Query: 253  DPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMTCYDSD---DANPRSVSSLSN 309
            DPE++R RTV+N+ DLRQNLEETMSSLRG+QVTHS+LE T +D++   + + RS+ SL+ 
Sbjct: 718  DPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETT-FDTNVTTEMSGRSILSLTG 776

Query: 310  RSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPMRSP--SKLS 367
            R +PLSWR GQSSPRLQAGDAPS+G         + +++ E   Y ++ P+R    S+ S
Sbjct: 777  RPTPLSWRLGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGS 836

Query: 368  HISRLELVESLDSDEVDLKS------GYMSDSDLMGKTMTEDDDITTG------------ 409
             +  +++ +    DE+DL+       GYMSD D++ K +   DDIT+G            
Sbjct: 837  SVCHVDVSDKA-GDEMDLEGISMDAPGYMSDGDVLSKNI-RTDDITSGYMTDGGLGLYTR 894

Query: 410  -----------------------------WDESSSISSGLSDASDNLSSEEFNASSSLNS 440
                                         WD+SSS+SSG+SD  DNLS+++ N SSS++S
Sbjct: 895  RLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISS 954

Query: 441  LPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAPKKLEYDSGS---LKMEPGT 497
              +TP +SR+N  +  +TD+EK S  E    W  +  +K+      D GS   +KMEPG 
Sbjct: 955  YANTPASSRKNLDV--QTDAEKHSQVERNSLWSGDDVKKS------DGGSDSGIKMEPG- 1005

Query: 498  SKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQ--SALKVAG 555
            SKWRR   +  D+S K    KK   +   GS ++G T  V +T P T  +    ALK  G
Sbjct: 1006 SKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAGALKTPG 1065

Query: 556  K---PEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKP-PSGIARPSTSG-SFGYKKP 610
                 + K ++KG+L+ K + ++RS SDAGR    ++KKP PS    P+ +  SFG+KK 
Sbjct: 1066 TGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQ 1125

Query: 611  P-PATGTATVMQTG-----GSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGA 664
               A G A +  +G      SATL KI KSS + V    GRK+S+D + + + G+LA  +
Sbjct: 1126 SGSAAGLAMITASGVTVTSRSATLGKIPKSSAL-VSRSAGRKSSMDGAQNQDDGYLALSS 1184

Query: 665  RSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASG 724
            R+N+QYRSLPRP+KS+S +  G R      +SSID S +S+K  GL   +L+EP+K A G
Sbjct: 1185 RTNLQYRSLPRPSKSNSRNGAGNRSS----TSSID-SNISSKSAGLPVPKLREPSKTALG 1239

Query: 725  RTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTP 784
             + P  VNQTD+EK  +         +++ +     P S+P   +  P A       PT 
Sbjct: 1240 SSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTL 1299

Query: 785  LR------------ATAKSFVKPPSLAN--LDKVNSNSLDLPSSSDTTHASKVPDLHATS 830
             R            ATA++      ++N         +LD PS S    +     L++ +
Sbjct: 1300 RRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKN 1359

Query: 831  -SASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQ 889
               +  PL S    SP+   +  S S + G    S  +V K+   +  +S LH S ES+ 
Sbjct: 1360 VDLNQSPLAS----SPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESID 1415

Query: 890  MPMS---LPSAFPSSTPVPTPPAPPAAP-TEEETEELTWSGSPRAG-------------- 931
            + +S   +PS   S+  + +       P     + + T S SP +               
Sbjct: 1416 ISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPR 1475

Query: 932  QLDSNQR-DRNTLPKKGLRY----QLQSQEETKERRHSHTIGGLPESDDQSELPSPPALP 986
            + DS+   DRNTLPKKGLRY    QL++QE+ KE   SH+ GGL ++   S   S  ++ 
Sbjct: 1476 KQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVT 1535

Query: 987  MSLSAKGQLTNIVSPTAAT-----TPRITRSNSIPTHEAAFELYSGSQM-GSTLSLAERP 1040
                 +   + + SPT  T      P + R++S+   +  ++ Y+ S+   S++SL E+ 
Sbjct: 1536 SPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKS 1595

Query: 1041 KGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATL 1100
            + M RSGSFRD  ++VHGS LSL SS SS YS+ EE+ QSE IRKLRREL++SQEKV+ L
Sbjct: 1596 RTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSE-IRKLRRELDASQEKVSAL 1654

Query: 1101 TSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVI 1160
            T+QL+ANA+LVAAFEQSL NMT RL+ L  TAE+KD+EL +LR+TI+ LKK+N+ AQA I
Sbjct: 1655 TTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAI 1714

Query: 1161 QGALNASETTPK--------ELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKS 1212
             G +N  E   K        +LRI+RQ+SSDS+SS+NS TSHSS+GS+ ++D+KKKK+K+
Sbjct: 1715 NGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKN 1774

Query: 1213 W---LRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSST 1269
            W   LRSSF +AF  KK PKSASS+SDIEE+   DSS PSSPKL H  +  ++P +++S 
Sbjct: 1775 WVNELRSSFKQAFGKKKSPKSASSHSDIEEMT--DSSLPSSPKLPHNGSTGSTPLLRNSH 1832

Query: 1270 SSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEKEMKLTDIRLEALNSA 1329
            S+S+                    +E  + E + V +LR+EL +KEMKLTDIRLEAL+SA
Sbjct: 1833 SNSL-------------------ISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSA 1873

Query: 1330 HQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGSSALS-SPRRSLGLAL 1388
            HQLDQLRE M+ MQ E++ LKAENDRLK     S GS   + P   ++S SPR+S+GL+ 
Sbjct: 1874 HQLDQLREAMNRMQSEIEKLKAENDRLK---SESQGSGCSRAPSQVSISASPRQSMGLS- 1929

Query: 1389 THSFGPSLADTDLSPMDGISTCGPKEEVT--LRVVVRMPPQHIIKGDLKQQEFFLGCSKV 1446
             HS   + + +    +D    C  ++E    +++VV    +   K D +   F +GC  V
Sbjct: 1930 QHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGV 1989

Query: 1447 SGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKRVLDAEPPEMPPCR 1506
            SGK  W +LD  V ++FK+YI  +DP S LGL+++S+ GYSI  +KR   +E PE+ PC 
Sbjct: 1990 SGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCG 2049

Query: 1507 RGVNN---ISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTGKTY 1563
              V     ISV++KGL E  +DSLVFE+LIPKP++Q Y+SLL++HRR++LSGPSGTGKTY
Sbjct: 2050 YLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTY 2109

Query: 1564 LTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPLVIL 1623
            L NRL+EY+V R GRE+T+G+++TFN+  +S K+L+ YLSNLA+Q + E    D+PLVI+
Sbjct: 2110 LANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVII 2169

Query: 1624 LDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPA 1683
            LD+L    S+ E+ NG L CKYHKCPYIIGT NQ    TPN  LH +FR +  +N+ EP 
Sbjct: 2170 LDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPV 2229

Query: 1684 NGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFL 1743
             GFL R+LRRKL+E++        EL++++DW+PK+W+HL+ FLE HS+SD  IGP  FL
Sbjct: 2230 KGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFL 2289

Query: 1744 SCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDTLPWPSA-- 1801
            SCPI ++  R WF DLWN SIIPYL E  ++G++++G++A WEDP +WV DT PW ++  
Sbjct: 2290 SCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQ 2349

Query: 1802 QQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLLKLQEAANYIESPD 1861
            Q +   L  L P  VG    + P E  T K   PS  + DPLM ML++LQEAANY  SP 
Sbjct: 2350 QHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANY-SSPQ 2408

Query: 1862 -----------RETILDPNLQATL 1874
                        + ILD +L++TL
Sbjct: 2409 SYDSDSNSNSHHDDILDSSLESTL 2432



 Score = 40.8 bits (94), Expect = 0.013
 Identities = 91/433 (21%), Positives = 156/433 (36%), Gaps = 92/433 (21%)

Query: 898  FPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLD--------------SNQRDRNTL 943
            +  S PV +PP PP++    E E L  S S   G  D              +N    + +
Sbjct: 292  YDKSKPVTSPPPPPSS---HEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAI 348

Query: 944  PKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSP--------PALPMSLSAKGQL 995
            P+ G   +   + ++   +HS T+  L       E P P        P    S+  K +L
Sbjct: 349  PQPGAATK-PWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKL 407

Query: 996  TNIVSPTAATTPRITRSNS------IPTHEAAFELYSGSQMGSTLSLA-ERPKGMIRSGS 1048
             N    + A     +R  S      +P+ E + EL + S+M +T+  A   PK       
Sbjct: 408  FNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSSPK------- 460

Query: 1049 FRDPTDDVHGSVLSLASSASSTYSSA----EERMQSEQIRKLRRELESSQEKVATLTSQL 1104
                        ++L   A  T+S A    +  ++  +  K +++ E  +EK   L  + 
Sbjct: 461  ------------IALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRA 508

Query: 1105 SANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQ--G 1162
            S               +T RL    E  E+           +  + KK+S+  + I   G
Sbjct: 509  S---------------VTERLDLKEEPKEDPS------GAAVPEMPKKSSKIASFIPKGG 547

Query: 1163 ALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLRSSFNKAF 1222
             LN++         K++  + S S +      S  G S  A A  K+ +       +   
Sbjct: 548  KLNSA---------KKEPMAPSHSGIPKPGMKSMPGKSPSAPAPSKEGERSRSGKLSSGL 598

Query: 1223 SIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHG-STETASPSIKSSTSSSVGTDVTEGP 1281
              +K        S    +A+ +   P    L H  S++T S S+   T+ + G++ T   
Sbjct: 599  PQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSV--GTTQTTGSN-TVSV 655

Query: 1282 AHPAPHTRLFHAN 1294
              P P  +  H N
Sbjct: 656  QLPQPQQQYNHPN 668


>gi|239747580 PREDICTED: similar to NAV1 protein [Homo sapiens]
          Length = 559

 Score = 1134 bits (2934), Expect = 0.0
 Identities = 559/559 (100%), Positives = 559/559 (100%)

Query: 1316 MKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGSS 1375
            MKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGSS
Sbjct: 1    MKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGSS 60

Query: 1376 ALSSPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVTLRVVVRMPPQHIIKGDLK 1435
            ALSSPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVTLRVVVRMPPQHIIKGDLK
Sbjct: 61   ALSSPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVTLRVVVRMPPQHIIKGDLK 120

Query: 1436 QQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKRVL 1495
            QQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKRVL
Sbjct: 121  QQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKRVL 180

Query: 1496 DAEPPEMPPCRRGVNNISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSG 1555
            DAEPPEMPPCRRGVNNISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSG
Sbjct: 181  DAEPPEMPPCRRGVNNISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSG 240

Query: 1556 PSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGI 1615
            PSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGI
Sbjct: 241  PSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGI 300

Query: 1616 GDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLT 1675
            GDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLT
Sbjct: 301  GDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLT 360

Query: 1676 FSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDF 1735
            FSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDF
Sbjct: 361  FSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDF 420

Query: 1736 LIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDT 1795
            LIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDT
Sbjct: 421  LIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDT 480

Query: 1796 LPWPSAQQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLLKLQEAAN 1855
            LPWPSAQQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLLKLQEAAN
Sbjct: 481  LPWPSAQQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLLKLQEAAN 540

Query: 1856 YIESPDRETILDPNLQATL 1874
            YIESPDRETILDPNLQATL
Sbjct: 541  YIESPDRETILDPNLQATL 559


>gi|161169017 neuron navigator 2 isoform 4 [Homo sapiens]
          Length = 1493

 Score = 1092 bits (2824), Expect = 0.0
 Identities = 665/1539 (43%), Positives = 935/1539 (60%), Gaps = 125/1539 (8%)

Query: 408  TGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAE 467
            T WD+SSS+SSG+SD  DNLS+++ N SSS++S  +TP +SR+N  +  +TD+EK S  E
Sbjct: 8    TSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDV--QTDAEKHSQVE 65

Query: 468  SGLSWFSESEEKAPKKLEYDSGS---LKMEPGTSKWRRERPESCDDSSKGGELKKPISLG 524
                W  +  +K+      D GS   +KMEPG SKWRR   +  D+S K    KK   + 
Sbjct: 66   RNSLWSGDDVKKS------DGGSDSGIKMEPG-SKWRRNPSDVSDESDKSTSGKKNPVIS 118

Query: 525  HPGSLKKGKTPPVAVTSPITHTAQ--SALKVAGK---PEGKATDKGKLAVKNTGLQRSSS 579
              GS ++G T  V +T P T  +    ALK  G     + K ++KG+L+ K + ++RS S
Sbjct: 119  QTGSWRRGMTAQVGITMPRTKPSAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPS 178

Query: 580  DAGRDRLSDAKKP-PSGIARPSTSG-SFGYKKPP-PATGTATVMQTG-----GSATLSKI 631
            DAGR    ++KKP PS    P+ +  SFG+KK    A G A +  +G      SATL KI
Sbjct: 179  DAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRSATLGKI 238

Query: 632  QKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGP 691
             KSS + V    GRK+S+D + + + G+LA  +R+N+QYRSLPRP+KS+S +  G R   
Sbjct: 239  PKSSAL-VSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSS- 296

Query: 692  RPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSD 751
               +SSID S +S+K  GL   +L+EP+K A G + P  VNQTD+EK  +         +
Sbjct: 297  ---TSSID-SNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCN 352

Query: 752  NISLKSIGSPESTPKNQASHPTATKLAELPPTPLR------------ATAKSFVKPPSLA 799
            ++ +     P S+P   +  P A       PT  R            ATA++      ++
Sbjct: 353  SVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVIS 412

Query: 800  N--LDKVNSNSLDLPSSSDTTHASKVPDLHATS-SASGGPLPSCFTPSPAPILNINSASF 856
            N         +LD PS S    +     L++ +   +  PL S    SP+   +  S S 
Sbjct: 413  NPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLAS----SPSSAHSAPSNSL 468

Query: 857  SQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTE 916
            + G    S  +V K+   +  +S LH S ES+ + +S       S  VP+  +       
Sbjct: 469  TWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLS-------SGGVPSHNSSTGLIAS 521

Query: 917  EETEELT---WSGSPRAGQLDSNQR-DRNTLPKKGLRY----QLQSQEETKERRHSHTIG 968
             + + LT    + S +    +S+   DRNTLPKKGLRY    QL++QE+ KE   SH+ G
Sbjct: 522  SKDDSLTPFVRTNSVKTTLSESDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAG 581

Query: 969  GLPESDDQSELPSPPALPMSLSAKGQLTNIVSPTAAT-----TPRITRSNSIPTHEAAFE 1023
            GL ++   S   S  ++      +   + + SPT  T      P + R++S+   +  ++
Sbjct: 582  GLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYD 641

Query: 1024 LYSGSQM-GSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQ 1082
             Y+ S+   S++SL E+ + M RSGSFRD  ++VHGS LSL SS SS YS+ EE+ QSE 
Sbjct: 642  PYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHGSSLSLVSSTSSVYSTPEEKCQSE- 700

Query: 1083 IRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDL 1142
            IRKLRREL++SQEKV+ LT+QL+ANA+LVAAFEQSL NMT RL+ L  TAE+KD+EL +L
Sbjct: 701  IRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNEL 760

Query: 1143 RETIDFLKKKNSEAQAVIQGALNASETTPK--------ELRIKRQNSSDSISSLNSITSH 1194
            R+TI+ LKK+N+ AQA I G +N  E   K        +LRI+RQ+SSDS+SS+NS TSH
Sbjct: 761  RKTIELLKKQNAAAQAAINGVINTPELNCKGNGTAQSADLRIRRQHSSDSVSSINSATSH 820

Query: 1195 SSIGSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQ 1254
            SS+GS+ ++D+KKKK+K+WLRSSF +AF  KK PKSASS+SDIEE+   DSS PSSPKL 
Sbjct: 821  SSVGSNIESDSKKKKRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMT--DSSLPSSPKLP 878

Query: 1255 HGSTETASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEK 1314
            H  +  ++P +++S S+S+                    +E  + E + V +LR+EL +K
Sbjct: 879  HNGSTGSTPLLRNSHSNSL-------------------ISECMDSEAETVMQLRNELRDK 919

Query: 1315 EMKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGS 1374
            EMKLTDIRLEAL+SAHQLDQLRE M+ MQ E++ LKAENDRLK     S GS   + P  
Sbjct: 920  EMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLK---SESQGSGCSRAPSQ 976

Query: 1375 SALS-SPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVT--LRVVVRMPPQHIIK 1431
             ++S SPR+S+GL+  HS   + + +    +D    C  ++E    +++VV    +   K
Sbjct: 977  VSISASPRQSMGLS-QHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWK 1035

Query: 1432 GDLKQQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHV 1491
             D +   F +GC  VSGK  W +LD  V ++FK+YI  +DP S LGL+++S+ GYSI  +
Sbjct: 1036 EDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEI 1095

Query: 1492 KRVLDAEPPEMPPCRRGVNN---ISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKH 1548
            KR   +E PE+ PC   V     ISV++KGL E  +DSLVFE+LIPKP++Q Y+SLL++H
Sbjct: 1096 KRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEH 1155

Query: 1549 RRLVLSGPSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQ 1608
            RR++LSGPSGTGKTYL NRL+EY+V R GRE+T+G+++TFN+  +S K+L+ YLSNLA+Q
Sbjct: 1156 RRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQ 1215

Query: 1609 IDRETGIGDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLH 1668
             + E    D+PLVI+LD+L    S+ E+ NG L CKYHKCPYIIGT NQ    TPN  LH
Sbjct: 1216 CNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLH 1275

Query: 1669 LSFRMLTFSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLE 1728
             +FR +  +N+ EP  GFL R+LRRKL+E++        EL++++DW+PK+W+HL+ FLE
Sbjct: 1276 HNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLE 1335

Query: 1729 KHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDP 1788
             HS+SD  IGP  FLSCPI ++  R WF DLWN SIIPYL E  ++G++++G++A WEDP
Sbjct: 1336 AHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDP 1395

Query: 1789 VEWVRDTLPWPSA--QQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAM 1846
             +WV DT PW ++  Q +   L  L P  VG    + P E  T K   PS  + DPLM M
Sbjct: 1396 AKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNM 1455

Query: 1847 LLKLQEAANYIESPD-----------RETILDPNLQATL 1874
            L++LQEAANY  SP             + ILD +L++TL
Sbjct: 1456 LMRLQEAANY-SSPQSYDSDSNSNSHHDDILDSSLESTL 1493


>gi|169218146 PREDICTED: similar to neuron navigator 3, partial [Homo
            sapiens]
          Length = 733

 Score =  664 bits (1713), Expect = 0.0
 Identities = 354/754 (46%), Positives = 495/754 (65%), Gaps = 43/754 (5%)

Query: 1143 RETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKD 1202
            RETI+ LK +NS AQA IQGALN  +  PK+LRI+RQ+SS+S+SS+NS TSHSSIGS  D
Sbjct: 1    RETIEMLKAQNSAAQAAIQGALNGPDHPPKDLRIRRQHSSESVSSINSATSHSSIGSGND 60

Query: 1203 ADAKKKKKKSW-------LRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQH 1255
            AD+KKKKKK+W       LRSSF +AF  KK  K  SS+SDIEE+   DSS P+SPKL H
Sbjct: 61   ADSKKKKKKNWVNSRGSELRSSFKQAFGKKKSTKPPSSHSDIEELT--DSSLPASPKLPH 118

Query: 1256 GSTETASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEKE 1315
             + +  S S+K S S+S   + TE                    E + + +L+SEL EKE
Sbjct: 119  NAGDCGSASMKPSQSASAICECTEA-------------------EAEIILQLKSELREKE 159

Query: 1316 MKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGST--PGQVPG 1373
            +KLTDIRLEAL+SAH LDQ+RE M+ MQ E+++LKAENDRLK   G ++  T  P +   
Sbjct: 160  LKLTDIRLEALSSAHHLDQIREAMNRMQNEIEILKAENDRLKAETGNTAKPTRPPSESSS 219

Query: 1374 SSALSSPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVTLRVVVRMPPQHIIKGD 1433
            S++ SS R+SLGL+L +        +D+   D     G K+  +++++V +   +    D
Sbjct: 220  STSSSSSRQSLGLSLNNLNITEAVSSDILLDDAGDATGHKDGRSVKIIVSISKGYGRAKD 279

Query: 1434 LKQQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKR 1493
             K Q + +G   VSGK  W +LD  + ++FK+Y+ ++D +++LGLS++ I  Y I  + R
Sbjct: 280  QKSQAYLIGSIGVSGKTKWDVLDGVIRRLFKEYVFRIDTSTSLGLSSDCIASYCIGDLIR 339

Query: 1494 VLDAEPPEMPPCRR--GVNNI-SVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRR 1550
              + E PE+ PC    G NNI +V+LKG++E  +DS VF+TLIPKP+ Q Y +LL++H R
Sbjct: 340  SHNLEVPELLPCGYLVGDNNIITVNLKGVEENSLDSFVFDTLIPKPITQRYFNLLMEHHR 399

Query: 1551 LVLSGPSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQID 1610
            ++LSGPSGTGKTYL N+LAEY++ +SGR+ TE  ++TFN+  +S K+LQ YL+NLA Q  
Sbjct: 400  IILSGPSGTGKTYLANKLAEYVITKSGRKKTEDAIATFNVDHKSSKELQQYLANLAEQCS 459

Query: 1611 RETGIGDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLS 1670
             +    ++P+VI+LD+L   GS+S++ NG L CKY+KCPYIIGT NQ V  +PN  LH +
Sbjct: 460  ADNNGVELPVVIILDNLHHVGSLSDIFNGFLNCKYNKCPYIIGTMNQGVSSSPNLELHHN 519

Query: 1671 FRMLTFSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKH 1730
            FR +  +N+ EP  GFL RYLRRKL+E + + N    +L++++DW+PK W+HL++FLE H
Sbjct: 520  FRWVLCANHTEPVKGFLGRYLRRKLIEIEIERNIRNNDLVKIIDWIPKTWHHLNSFLETH 579

Query: 1731 STSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVE 1790
            S+SD  IGP  FL CP+ +E  R WF+DLWN S++PY+ E  ++G++++G++  WEDP +
Sbjct: 580  SSSDVTIGPRLFLPCPMDVEGSRVWFMDLWNYSLVPYILEAVREGLQMYGKRTPWEDPSK 639

Query: 1791 WVRDTLPWPSA--QQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLL 1848
            WV DT PW SA   Q+   L  L P  VG  S  S  E  T K    +  + DPLM ML+
Sbjct: 640  WVLDTYPWSSATLPQESPALLQLRPEDVGYESCTSTKEATTSKHIPQTDTEGDPLMNMLM 699

Query: 1849 KLQEAANYIESPD--------RETILDPNLQATL 1874
            KLQEAANY  +           E ILD +L++TL
Sbjct: 700  KLQEAANYSSTQSCDSESTSHHEDILDSSLESTL 733


>gi|239750047 PREDICTED: similar to neuron navigator 2, partial [Homo
            sapiens]
          Length = 453

 Score =  468 bits (1203), Expect = e-131
 Identities = 230/452 (50%), Positives = 311/452 (68%), Gaps = 17/452 (3%)

Query: 1439 FFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKRVLDAE 1498
            F +GC  VSGK  W +LD  V ++FK+YI  +DP S LGL+++S+ GYSI  +KR   +E
Sbjct: 3    FLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSE 62

Query: 1499 PPEMPPCRRGVNN---ISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSG 1555
             PE+ PC   V     ISV++KGL E  +DSLVFE+LIPKP++Q Y+SLL++HRR++LSG
Sbjct: 63   TPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSG 122

Query: 1556 PSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGI 1615
            PSGTGKTYL NRL+EY+V R GRE+T+G+++TFN+  +S K+L+ YLSNLA+Q + E   
Sbjct: 123  PSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNA 182

Query: 1616 GDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLT 1675
             D+PLVI+LD+L    S+ E+ NG L CKYHKCPYIIGT NQ    TPN  LH +FR + 
Sbjct: 183  VDMPLVIILDNLHHVSSLGEIFNGLLNCKYHKCPYIIGTMNQATSSTPNLQLHHNFRWVL 242

Query: 1676 FSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDF 1735
             +N+ EP  GFL R+LRRKL+E++        EL++++DW+PK+W+HL+ FLE HS+SD 
Sbjct: 243  CANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDV 302

Query: 1736 LIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDT 1795
             IGP  FLSCPI ++  R WF DLWN SIIPYL E  ++G++++G++A WEDP +WV DT
Sbjct: 303  TIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRRAPWEDPAKWVMDT 362

Query: 1796 LPWPSA--QQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLLKLQEA 1853
             PW ++  Q +   L  L P  VG    + P E  T K   PS  + DPLM ML++LQEA
Sbjct: 363  YPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEA 422

Query: 1854 ANYIESPD-----------RETILDPNLQATL 1874
            ANY  SP             + ILD +L++TL
Sbjct: 423  ANY-SSPQSYDSDSNSNSHHDDILDSSLESTL 453


>gi|16975496 cortactin binding protein 2 [Homo sapiens]
          Length = 1663

 Score =  106 bits (264), Expect = 2e-22
 Identities = 88/332 (26%), Positives = 156/332 (46%), Gaps = 41/332 (12%)

Query: 1474 STLGLSTESIHGYSISHVKRVLDAEPPEMP---PCRRGVNNISVSLKGLKEKCVDSLVFE 1530
            S +GLS  SI   ++ +V   +     + P     +    +I+V L G +E C+ S+ + 
Sbjct: 1043 SNIGLSARSIRSITLGNVPWSVGQSFAQSPWDFMRKNKAEHITVLLSGPQEGCLSSVTYA 1102

Query: 1531 TLIPKPMMQHYISLLLKHRRLVLSGPSGTGKTYLTNRLAEYLVER------SGREVTEGI 1584
            ++IP  MMQ+Y+ L+ ++  ++  GP G+ + Y+ ++LA  L  R      S   V   +
Sbjct: 1103 SMIPLQMMQNYLRLVEQYHNVIFHGPEGSLQDYIVHQLALCLKHRQMAAGFSCEIVRAEV 1162

Query: 1585 VSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPLVILLDDLSEAGSISELV------- 1637
             + F+  Q     L L++S+ A  I  +       ++I+L++L E  S+SEL+       
Sbjct: 1163 DAGFSKEQL----LDLFISS-ACLIPVKQSPSKKKIIIILENL-EKSSLSELLRDFLAPL 1216

Query: 1638 --------------NGALTCKY-HKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEP 1682
                          NG   C Y H+  +++GT  +      +  +   FR +    + EP
Sbjct: 1217 ENRSTESPCTFQKGNGLSECYYFHENCFLMGTIAKACLQGSDLLVQQHFRWVQLRWDGEP 1276

Query: 1683 ANGFLVRYLRRKLVES-DSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCF 1741
              G L R+LRRK+V        +  + + +++DW   +W  L++ L +  T + L+GP +
Sbjct: 1277 MQGLLQRFLRRKVVNKFKGQAPSPCDPVCKIVDWALSVWRQLNSCLARLGTPEALLGPKY 1336

Query: 1742 FLSCPI---GIEDFRTWFIDLWNNSIIPYLQE 1770
            FLSCP+     +    W   LWN  I P +QE
Sbjct: 1337 FLSCPVVPGHAQVTVKWMSKLWNGVIAPRVQE 1368



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 48/219 (21%), Positives = 88/219 (40%), Gaps = 36/219 (16%)

Query: 1079 QSEQIRKLRRELESSQEKVATLTSQLSA----NANLVAAFEQSLVNMTSRLRHLAETAEE 1134
            +++++  +  +LE  ++K   L  +LSA    +  + A  E+ L    +    L      
Sbjct: 188  EAQKLEDVMAKLEEEKKKTNELEEELSAEKRRSTEMEAQMEKQLSEFDTEREQLRAKLNR 247

Query: 1135 KDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSH 1194
            ++    DL+E ID ++K       +I+     S++ P  L + R+     + S++  T  
Sbjct: 248  EEAHTTDLKEEIDKMRK-------MIEQLKRGSDSKPS-LSLPRKTKDRRLVSISVGTEG 299

Query: 1195 SSIGS--------SKDADAKKK---------KKKSWLRSSFNK------AFSIKKGPKSA 1231
            +   S        +++AD  KK            S L S+  K      A   + G    
Sbjct: 300  TVTRSVACQTDLVTENADHMKKLPLTMPVKPSTGSPLVSANAKGSVCTSATMARPGIDRQ 359

Query: 1232 SSYSDIEEIATPDSSAPSSPKLQHGSTETAS-PSIKSST 1269
            +SY D+   + P    PS+ K++     T S P   SST
Sbjct: 360  ASYGDLIGASVPAFPPPSANKIEENGPSTGSTPDPTSST 398


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 115/468 (24%), Positives = 167/468 (35%), Gaps = 95/468 (20%)

Query: 509  DDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSA--LKVAGKPEGKATDKGK 566
            D SS       P+ +  P S+  G T P+ VTSP + +   A  L V G       D   
Sbjct: 3701 DASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTP 3760

Query: 567  LAVKNTGLQRSS-------SDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATV 619
            L V +T    +        +D       D  + P       +S S G+  P P T T++ 
Sbjct: 3761 LPVTDTSSASTRHATPLPVTDTSSASTDDTTRLP---VTDVSSASTGHATPLPVTSTSSA 3817

Query: 620  MQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSN--SAEPGFLAPGARSNIQYRSLPRPA 677
              TG +  L     SS        G  TSL V++  SA  G             + P P 
Sbjct: 3818 -STGDTTPLPVTDTSS-----VSTGHATSLPVTSRSSASTG------------HATPLPV 3859

Query: 678  KSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTD-- 735
              +S SV+ G   P PV+S+      S   G  TP  +  P+  ++G  TP PV  T   
Sbjct: 3860 TDTS-SVSTGHATPLPVTSTS-----SVSTGHATPLPVTSPSSASTGHATPVPVTSTSSA 3913

Query: 736  -----------REKEKAKAKAVALDSDNISLKSIGSPESTPKNQAS-----HPTATKLAE 779
                            +   A  L   + S  S G   + P   AS     H T   L  
Sbjct: 3914 STGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTS 3973

Query: 780  L------PPTPLRATAKSFVK-----PPSLANLDKVNSNS-----LDLPSSSDTTHASKV 823
            L        TPL  T  S        P  + +L  V++       + +PSS+ + H + +
Sbjct: 3974 LSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSL 4033

Query: 824  P--DLHATSSASGGPLPSCFTPS-------PAPILNINSASFSQGLEL--------MSGF 866
            P  D  + S+  G PLP   T S       P P+ + +SAS      L         +G 
Sbjct: 4034 PVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGH 4093

Query: 867  SVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAP 914
            + P        +S  H +      P+++ SA  +ST     P     P
Sbjct: 4094 ATPLPVTSLSSVSTGHAT------PLAVSSATSASTVSSDSPLKMETP 4135



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 195/854 (22%), Positives = 294/854 (34%), Gaps = 99/854 (11%)

Query: 522  SLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDA 581
            S+GH  SL      PV  TS I+    + L V             L V +T    S+  A
Sbjct: 2874 SIGHATSL------PVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTS-SASTGHA 2926

Query: 582  GRDRLSDAKKPPSGIARP-----STSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSG 636
                ++      +G A P     ++S S G+  P P T  ++V  TG +  L     SS 
Sbjct: 2927 NPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSV-STGDTTPLPVTSPSSA 2985

Query: 637  -------IPVKPVN----GRKTSLDVSN--SAEPGFLAP----GARSNIQYRSLPRPAKS 679
                   +PV   +    G+ T+L V++  SA  G   P       S    ++ P P  S
Sbjct: 2986 STGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTS 3045

Query: 680  SSMSVTGGRGGPRPVSSSIDPSL-----------LSTKQGGLTPSRLKEPTKVASGRTTP 728
             S SV+ G   P PV+S    S             S   G  TP  +   + V++G TTP
Sbjct: 3046 LS-SVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTP 3104

Query: 729  APVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRAT 788
             PV         +   A +L   + S  S G   S P    S         LP T   ++
Sbjct: 3105 LPVTSPS---SASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSS 3161

Query: 789  AKSFVKPPSLANLDKVNSNS-----LDLPSSSDTTHASKVPDLHATS--SASGG---PLP 838
            +     P  +     V++       +   SS+ T HA+    LH TS  SAS G   P+P
Sbjct: 3162 STGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATP---LHVTSPSSASTGDTTPVP 3218

Query: 839  SCFTPS-------PAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMP 891
               T S       P P+  ++SAS      L         T     L   + S  S    
Sbjct: 3219 VTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDT 3278

Query: 892  MSLPSAFPSS------TPVPTPPAPPAAPTEEETEELTWSGSPRAGQLD----SNQRDRN 941
            M LP   PSS      TP+P      A+        +T + S   G       ++    +
Sbjct: 3279 MPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSAS 3338

Query: 942  TLPKKGLRYQLQSQEETKERRHSH-TIGGLPESDDQSELPSPPALPMSLSAKGQL----T 996
            T     L     S   T      H TI     + D S LP   A   S      L    T
Sbjct: 3339 TGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDT 3398

Query: 997  NIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSGSFRDPTDDV 1056
            + VS   AT   +T  +S+ T +      + +   ST      P   + S S  D T  +
Sbjct: 3399 SSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLL 3458

Query: 1057 --------HGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANA 1108
                     G    L  + +S+ S+ +               +++   V +L+S  + + 
Sbjct: 3459 VTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDT 3518

Query: 1109 NLVAAFEQSLVNMTSRLRHLAET----AEEKDTELLDLRETIDFLKKKNSEAQAVIQGAL 1164
              +   + S V+ T     L  T    A   DT  L + +T      + +     I  + 
Sbjct: 3519 TPLLVTDASSVS-TGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSS 3577

Query: 1165 NASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLRSS-----FN 1219
            ++  TTP  +      S+  ++ L+ +TS SS  +            S            
Sbjct: 3578 SSGHTTPLPVTSTSSVSTGHVTPLH-VTSPSSASTGHVTPLPVTSTSSASTGHATPLLVT 3636

Query: 1220 KAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGTDVTE 1279
             A S+  G  +    +D    +T D++          ST  A+P   +S SS    D T 
Sbjct: 3637 DASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTP 3696

Query: 1280 GPAHPAPHTRLFHA 1293
             P   A      HA
Sbjct: 3697 LPVTDASSASTGHA 3710



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 99/388 (25%), Positives = 144/388 (37%), Gaps = 57/388 (14%)

Query: 509  DDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSA--LKVAGKPEGKATDKGK 566
            D SS       P+ L    S+  G T P+ VT   + +   A  L V         D   
Sbjct: 2757 DASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTP 2816

Query: 567  LAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARP-----STSGSFGYKKPPPATGTATVMQ 621
            L V +T    S+  A    ++D     +G A P     ++S S G+    P T T++   
Sbjct: 2817 LPVTDTS-SASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSA-- 2873

Query: 622  TGGSATLSKIQKSSGI------------PVKPVNGRKTSLDVSN--SAEPGFLAP----G 663
            + G AT   +  +S I            P     G  T L V++  SA  G   P     
Sbjct: 2874 SIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTS 2933

Query: 664  ARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVAS 723
              S     + P P   +S + TG    P PV+S     L S   G  TP  +  P+  ++
Sbjct: 2934 PSSASTGHATPLPVTDTSSASTG-HATPLPVTS-----LSSVSTGDTTPLPVTSPSSAST 2987

Query: 724  GRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPT 783
            G TTP PV  T      +  +A AL   + S  S G     P    S  +  +   LP T
Sbjct: 2988 GHTTPLPVTDT---SSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVT 3044

Query: 784  PLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASK--VPDLHATSSASGGPLP--- 838
             L + +     P  + +           PSS+ T HA+   V D  + S+    PLP   
Sbjct: 3045 SLSSVSTGDTTPLPVTS-----------PSSASTGHATPLLVTDASSASTGQATPLPVTS 3093

Query: 839  ----SCFTPSPAPILNINSASFSQGLEL 862
                S    +P P+ + +SAS      L
Sbjct: 3094 LSSVSTGDTTPLPVTSPSSASTGHATSL 3121



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 160/682 (23%), Positives = 256/682 (37%), Gaps = 128/682 (18%)

Query: 275  TMSSLRGSQVTHSSLEMTCYDSDDANPRSVSSLSNRS----------SPLSWRYGQSSPR 324
            T S+  G        + +   +  A P  V+SLS+ S          SP S   G ++P 
Sbjct: 3014 TSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPL 3073

Query: 325  LQAGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPMRSPSKLS--HISRLELVESLDSDE 382
            L    + +  G  ++   P   +       +  +P+ SPS  S  H + L + ++  +  
Sbjct: 3074 LVTDASSASTG--QATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSAST 3131

Query: 383  VDLKSGYMSDS------DLMGKTMTEDDDITTG------WDESSSISSGLSDASDNLSSE 430
             D  S  ++D+      D     +T+    +TG        E+SS+S+G   A+  L ++
Sbjct: 3132 GDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTG--HATPLLVTD 3189

Query: 431  EFNASSSLNS---LPSTPTASRRNSTIVLRTDSEKRS------LAESGLSWFSESEEKAP 481
              +AS+   +   + S  +AS  ++T V  TD+   S      L  +GLS  S       
Sbjct: 3190 ASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSAS------- 3242

Query: 482  KKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTS 541
                  +G     P T           D SS       P+ + +  S+  G T P+ VTS
Sbjct: 3243 ------TGDTTRLPVT-----------DISSASTGQATPLPVTNTSSVSTGDTMPLPVTS 3285

Query: 542  PITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPST 601
            P + +            G AT    L V +T    SS+  G      A   P      ++
Sbjct: 3286 PSSAST-----------GHATP---LPVTST----SSASTGH-----ATPVP---VTSTS 3319

Query: 602  SGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVS--NSAEPGF 659
            S S G+  P P T T++   TG +  L     SS        G  T L V+  +SA  G 
Sbjct: 3320 SASTGHTTPLPVTDTSSA-STGDTTPLPVTSPSSAS-----TGHTTPLHVTIPSSASTGD 3373

Query: 660  LAP----GARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRL 715
             +     GA S     + P P   +S SV+ G   P PV+S     L S   G  TP  +
Sbjct: 3374 TSTLPVTGASSASTGHATPLPVTDTS-SVSTGHATPLPVTS-----LSSVSTGDTTPLPV 3427

Query: 716  KEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTAT 775
             + +  ++G+ TP PV              +  D+ ++   S G     P    S  +  
Sbjct: 3428 TDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSV---STGHATPLPVTDTSSASTG 3484

Query: 776  KLAELPPTPLRATAKSFVKPPSLANLDKVNSNS-----LDLPSSSDTTHASKVPDLHATS 830
                LP T   + +     P  + +L  V++       +   SS  T HA+ +P +  TS
Sbjct: 3485 DTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLP-VTDTS 3543

Query: 831  SASGGPLPSCFTPSPAPILNINSASFSQGLEL--------MSGFSVPKETRMYPKLSGLH 882
            SAS G        +  P+ + +SAS  Q   L         SG + P        +S  H
Sbjct: 3544 SASTG------DTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGH 3597

Query: 883  RSMESLQMPMSLPSAFPSSTPV 904
             +   +  P S  +   +  PV
Sbjct: 3598 VTPLHVTSPSSASTGHVTPLPV 3619



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 154/718 (21%), Positives = 254/718 (35%), Gaps = 116/718 (16%)

Query: 274  ETMSSLRGSQVTHSSLEMTCYDSDDANPRSVSSLSNRS----------SPLSWRYGQSSP 323
            +T S+  G   +    + +   + D  P  V+S S+ S          SP S   G ++P
Sbjct: 1461 DTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATP 1520

Query: 324  -------RLQAGDA---PSVGGSCRSEG--TPAWYMHGERAHYSHT--MPMRSPSKLS-- 367
                       GD    P    S  S G  TP            HT  +P+ SPS  S  
Sbjct: 1521 LPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTG 1580

Query: 368  HISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDDITTGWDESSSISSGLSDASDNL 427
            H + L + ++  +          S  D     +T     +TG      ++   S ++ + 
Sbjct: 1581 HTTPLPVTDTSSA----------SKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDT 1630

Query: 428  SSEEFNASSSLNSLPSTP-------TASRRNSTIVLRTDSEKRS------LAESGLSWFS 474
            +      +SSL++  +TP       +AS  ++T +  T +   S      L  +GLS  S
Sbjct: 1631 TPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLS--S 1688

Query: 475  ESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKT 534
             + +   +    D  S      T       P +   S   G+   P+ +  P S   G  
Sbjct: 1689 ATTDDTTRLPVTDVSSASTGQATPL-----PVTSLSSVSTGDTT-PLPVTSPSSASTGHA 1742

Query: 535  PPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSD-AGRDRLSDAKKPP 593
             P+ VT   + +   A  +        +      +  TGL  +S+D   R  ++D     
Sbjct: 1743 SPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSAS 1802

Query: 594  SGIARP-----STSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTS 648
            +G A P      +S S G   P P T  ++   TG + +L        IP    +G  TS
Sbjct: 1803 TGQAIPLPVTSPSSASTGDTTPLPVTDASSA-STGDTTSLPVT-----IPSSASSGHTTS 1856

Query: 649  LDVSNSAE------PGFLAPGARSNIQYRSLPRPAKSSSMSVTG---------------G 687
            L V++++          L   A S     + P P   ++ + TG               G
Sbjct: 1857 LPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTG 1916

Query: 688  RGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVA 747
                 PV+S     L S   G  TP  +  P+  +SG TTP PV             A +
Sbjct: 1917 HATSLPVTS-----LSSASTGDTTPLPVTSPSSASSGHTTPLPVTDA---SSVPTGHATS 1968

Query: 748  LDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSN 807
            L   + S  S G     P   AS  +      LP T   + +     P  + +L   ++ 
Sbjct: 1969 LPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTG 2028

Query: 808  SLDLPSSSDTTHAS-------KVPDLHATSSASGGPLP-----SCFTPSPAPILNINSAS 855
                   +DT+ AS        V  L + S+    PLP     S  T    P+L  +++S
Sbjct: 2029 DTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASS 2088

Query: 856  FSQG------LELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTP 907
             S G      +   S  S    T ++   +    + ++  +P++ PS+  +    P P
Sbjct: 2089 VSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLP 2146



 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 175/851 (20%), Positives = 296/851 (34%), Gaps = 122/851 (14%)

Query: 509  DDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLA 568
            D SS       P+ +    S+  G T P+ VTSP + +   A  +       A+      
Sbjct: 1365 DASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATP 1424

Query: 569  VKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATL 628
            +  T     S+D        A   P  I    ++ S G+  P P T T++   TG + +L
Sbjct: 1425 LPVTDASSVSTD-------HATSLPVTIP---SAASTGHTTPLPVTDTSSA-STGQATSL 1473

Query: 629  SKIQKSS-------GIPVKPVN----GRKTSLDVSN--SAEPGFLAPGARSNIQYRS--- 672
                 SS        +PV   +    G  T L V++  SA  G   P   +++   S   
Sbjct: 1474 LVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGD 1533

Query: 673  -LPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPV 731
             +P P  S S + TG    P PV+   D S +ST  G  TP  +  P+  ++G TTP PV
Sbjct: 1534 TMPLPVTSPSSASTGDTT-PLPVT---DASSVST--GHTTPLPVTSPSSASTGHTTPLPV 1587

Query: 732  NQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKS 791
              T      +K     L   + S  S G     P    S  +      LP T   + +  
Sbjct: 1588 TDTS---SASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTG 1644

Query: 792  FVKP-----PSLANLDKVNSNSLDLPSSSDTTHASKVP------------------DLHA 828
               P     PS A+        +   SS+ T HA+ +P                  D+ +
Sbjct: 1645 HATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSS 1704

Query: 829  TSSASGGPLP-------SCFTPSPAPILNINSASFSQGLELM--------SGFSVPKETR 873
             S+    PLP       S    +P P+ + +SAS      L+        +G + P    
Sbjct: 1705 ASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVT 1764

Query: 874  MYPKLSGLHRSM------------ESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEE 921
                +S  H +             ++ ++P++  S+  +   +P P   P++ +  +T  
Sbjct: 1765 DTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTP 1824

Query: 922  LTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPS 981
            L  + +  A   D+      T+P         S   T     S          D S + +
Sbjct: 1825 LPVTDASSASTGDTTSLPV-TIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVST 1883

Query: 982  PPALPMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAA---FELYSGSQMGSTLSLAE 1038
                P+ ++     TN  S    T   +T ++S+ T  A        S +  G T  L  
Sbjct: 1884 GDTTPLPVTD----TNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPV 1939

Query: 1039 RPKGMIRSGSFRD-PTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKV 1097
                   SG     P  D        A+S   T +S+     +  +       ++S    
Sbjct: 1940 TSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVT----DASSVST 1995

Query: 1098 ATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQ 1157
               T     + + V+  + + + +TS       +A   DT  L + +T      +++   
Sbjct: 1996 GHATPLPVTDTSSVSTGQATPLPVTS-----LSSASTGDTTPLPVTDTSSASTGQDTPLP 2050

Query: 1158 AVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLRSS 1217
                 +++  +TTP  +      S+   + L  +T  SS+ +                  
Sbjct: 2051 VTSLSSVSTGDTTPLPVTSPSSASTGHATPL-LVTDASSVSTGHATSLL----------- 2098

Query: 1218 FNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGTDV 1277
               A S+  G  +A   +D   ++T D++          ST   +P   + TSS     V
Sbjct: 2099 VTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSS-----V 2153

Query: 1278 TEGPAHPAPHT 1288
            + G A   P T
Sbjct: 2154 STGHATSLPVT 2164



 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 105/449 (23%), Positives = 165/449 (36%), Gaps = 59/449 (13%)

Query: 509  DDSSKGGELKKPISLGHPGSLKKGKTPPVAVT--SPITHTAQSALKVAGKPEGKATDKGK 566
            D SS       P+ +    S+  G T P+ VT  S ++    + L V         D  +
Sbjct: 3429 DASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTR 3488

Query: 567  LAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSA 626
            L V +T    SS+  G+        P + ++  ST  +      P     A+ + TG + 
Sbjct: 3489 LPVTDT----SSASTGQA----TPLPVTSLSSVSTGDT-----TPLLVTDASSVSTGHAT 3535

Query: 627  TLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTG 686
             L     SS        G  T L V++++        + S  Q   LP    SSS S   
Sbjct: 3536 PLPVTDTSSAS-----TGDTTRLPVTDTS--------SASTGQATPLPVTIPSSSSS--- 3579

Query: 687  GRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAV 746
            G   P PV+S+      S   G +TP  +  P+  ++G  TP PV  T           +
Sbjct: 3580 GHTTPLPVTSTS-----SVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLL 3634

Query: 747  ALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNS 806
              D+ ++   S G     P   AS  +      LP T   + +     P  + +L  V++
Sbjct: 3635 VTDASSV---STGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVST 3691

Query: 807  -NSLDLP----SSSDTTHASKVPDLHATSSASGGPLPSCFT---------PSPAPILNIN 852
             ++  LP    SS+ T HA+ +P    +S ++G  +P   T          +P P+  ++
Sbjct: 3692 GDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLS 3751

Query: 853  SASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSS------TPVPT 906
            SAS      L    +    TR    L     S  S      LP    SS      TP+P 
Sbjct: 3752 SASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPV 3811

Query: 907  PPAPPAAPTEEETEELTWSGSPRAGQLDS 935
                 A+  +     +T + S   G   S
Sbjct: 3812 TSTSSASTGDTTPLPVTDTSSVSTGHATS 3840



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 131/575 (22%), Positives = 203/575 (35%), Gaps = 91/575 (15%)

Query: 421  SDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKA 480
            S  SD +S     A+ + +++P TP +         +T++   S + SG ++ +     A
Sbjct: 916  SRGSDTISLAS-QATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNA 974

Query: 481  -PKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAV 539
             P  + Y S +       S          D SS       P+ +  P S+  G T P+ V
Sbjct: 975  TPLPVTYASSA-------STGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPV 1027

Query: 540  T----------SPITHTAQSALKVAGKPEGKATDKGKLAVKN------TGLQRSSS-DAG 582
            T          +P+  T+ S+           TD    +  +      T L  +S+ D  
Sbjct: 1028 TDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTT 1087

Query: 583  RDRLSDAKKPPSGIARP-----STSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGI 637
               ++D     +G A       ++S S G+  P P T T++   + G AT   +  +S +
Sbjct: 1088 PLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSA--STGHATSLPVTDTSSV 1145

Query: 638  PVKPVNGRKTSLDVSN--SAEPGFLAPGARSNIQYRSL----PRPAKSSSMSVTG----- 686
                  G  T L V++  SA  G   P   +++   S     P P  S S + TG     
Sbjct: 1146 ST----GHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPL 1201

Query: 687  ----------GRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDR 736
                      G   P PV+   D S +ST      P  +  P+  ++G TTP PV  T  
Sbjct: 1202 LVTDTSSASTGHATPLPVT---DASSVSTDHATSLPVTI--PSAASTGHTTPLPVTDTSS 1256

Query: 737  EKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPP--------TPLRAT 788
                     +  D+ ++S         T  + AS    T L    P        TPL  T
Sbjct: 1257 ASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVT 1316

Query: 789  AKSF----------VKPPSLANLDKVNSNSLDLPSSSDTTHAS--KVPDLHATSSASGGP 836
            + S           V  PS A+        +   SS  T H +   V D  + S+    P
Sbjct: 1317 SLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATP 1376

Query: 837  LP-------SCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQ 889
            LP       S    +P P+ + +SAS      L+   +    T     L     S  S  
Sbjct: 1377 LPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTD 1436

Query: 890  MPMSLPSAFPSSTPV-PTPPAPPAAPTEEETEELT 923
               SLP   PS+     T P P    +   T + T
Sbjct: 1437 HATSLPVTIPSAASTGHTTPLPVTDTSSASTGQAT 1471



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 183/755 (24%), Positives = 278/755 (36%), Gaps = 142/755 (18%)

Query: 299  ANPRSVSSLSNRSS----PLSWRYGQSSPRLQAGDAPSVGGSCRSEG--TPAWYMHGERA 352
            A P  V+SLS+ S+    PL      S+   Q    P    S  S G  TP        A
Sbjct: 2014 ATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSA 2073

Query: 353  HYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGY-----------MSDSDLMGKTMT 401
               H  P+   +  S +S       L +D   + +G+           +S  D     +T
Sbjct: 2074 STGHATPLLV-TDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVT 2132

Query: 402  EDDDITTG------WDESSSISSGLSDA---SDNLSSEEFNASSSLNSLPSTPT--ASRR 450
                 +TG        ++SS+S+G + +   +D  S+   +A+S    LP T T  AS  
Sbjct: 2133 SPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHATS----LPVTDTSSASTG 2188

Query: 451  NSTIVLRTDSEKRSLAESG----LSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPE 506
            ++T +  TD+   S  ++      S  S S   A   L  D+ S      T         
Sbjct: 2189 HATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPL----PVT 2244

Query: 507  SCDDSSKGGELKKPI------SLGHPGSL--------KKGKTPPVAVTSPITHTAQSALK 552
            S   +S G     P+      S GH  SL          G T P+ VTSP + +   A  
Sbjct: 2245 SLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATP 2304

Query: 553  V-----AGKPEGKATDKG--KLAVKNTG-------LQRSSSDAGRD---RLSDAKKPPSG 595
            +     +    G AT      L+  +TG          SS+  G      ++DA    +G
Sbjct: 2305 LHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTG 2364

Query: 596  IARP-----STSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSG-------IPVKPVN 643
               P     S+S S G+  P P T  ++   TG +  L     SS        +PV  ++
Sbjct: 2365 DTTPLPVTSSSSASSGHTTPLPVTDASSA-STGDTTPLPVTDTSSASTGHATHLPVTGLS 2423

Query: 644  ----GRKTSLDVSN--SAEPGFLAPGARSNIQYRSL----PRPAKSSSMSVTGGRGGPRP 693
                G  T L V+N  SA  G   P   ++    S     P P   +S SV+ G   P  
Sbjct: 2424 SASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTS-SVSTGHTTPLL 2482

Query: 694  VSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNI 753
            V+   D S +ST  G  T   +  P+  ++G TTP PV  T              ++ ++
Sbjct: 2483 VT---DASSVST--GDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSL 2537

Query: 754  SLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKP-PSLANLDKVNSNSLDLP 812
            S +   S   T  + AS   AT    LP T   A +     P P  +       ++  LP
Sbjct: 2538 STRHATSLHVTSPSSASTGHAT---SLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLP 2594

Query: 813  ----SSSDTTHASKVPDLHATSSASGG---PLPSCFTPS-------PAPILNINSASFSQ 858
                 S+ T  A+ +P +  TSSAS G   PLP   T S       P P+ N +S S   
Sbjct: 2595 VTDTYSASTGQATPLP-VTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGH 2653

Query: 859  GLEL--------MSGFSVPKETRMYPKLSGLHRSM------------ESLQMPMSLPSAF 898
               L         +G + P        +S  H +              +  +P+++PS+ 
Sbjct: 2654 ATPLHVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSA 2713

Query: 899  PS--STPVPTPPAPPAAPTEEETEELTWSGSPRAG 931
             S  +TP+P   A   +     +  +T + S   G
Sbjct: 2714 SSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTG 2748



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 165/805 (20%), Positives = 277/805 (34%), Gaps = 162/805 (20%)

Query: 152  SPAGGAKTPLAPLAPNLGKPSRIPRGPYAEVKPLSKAPEAAVSEDGKSDDELLSSKAKAQ 211
            S + GA T L    P+ G    IPR P         +  +A+ E G+      S      
Sbjct: 507  STSTGAATRLVTGNPSTGTAGTIPRVP---------SKVSAIGEPGEPTT-YSSHSTTLP 556

Query: 212  KSSGPVPSAKGQEE-----RAFLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQ--- 263
            K++G     +  +E      A L      V  ++        S MLD  + ++ T     
Sbjct: 557  KTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPST 616

Query: 264  NVLDLRQNLEETMSSLRGSQVTHSSLEMTCYDSDDANPRSVSSLSNRSSPLS-----WRY 318
            N   +         S   SQ  H+    T  +S     RSVS +++  +  +        
Sbjct: 617  NHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTT--RSVSPMTDTKTVTTPGSSFTAS 674

Query: 319  GQSSPRLQAGDAPSVG----------GSCRSEGTPAWYMHGERAHYSHTMPMRSPSKLSH 368
            G S   +   DAP++           G   +   P   +    + +  T+     + LS 
Sbjct: 675  GHSPSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSK 734

Query: 369  ISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDD---ITTGWDESSSISSGLSDASD 425
               L L  S+ S     +  + S S       T  D    +T      S+ +SG +  S+
Sbjct: 735  TGALTLANSVVSTPGGPEGQWTSAS-----ASTSPDTAAAMTHTHQAESTEASGQTQTSE 789

Query: 426  NLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESG-LSWFSESEEKAPKKL 484
              SS     S + ++  +TP++S  + T    T S    ++ SG  + FS +  +     
Sbjct: 790  PASS----GSRTTSAGTATPSSSGASGT----TPSGSEGISTSGETTRFSSNPSR----- 836

Query: 485  EYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPIT 544
                         S   +   E    S+  G +  P+S G   S+  G            
Sbjct: 837  ------------DSHTTQSTTELLSASASHGAI--PVSTGMASSIVPGTF---------- 872

Query: 545  HTAQSALKVAGKPEGKATDKGKLAV--------KNTGLQRSSSDAGRDRLSDAKKPPSGI 596
            H   S    AG+P G+++     A         +    QR+ +  G D +S A +     
Sbjct: 873  HPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTF 932

Query: 597  AR----PSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVS 652
            +     P +  S G   P   T T +   +G + T + I  ++ +PV            +
Sbjct: 933  STVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVT----------YA 982

Query: 653  NSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTP 712
            +SA  G   P                   + VT             D S +ST  G  TP
Sbjct: 983  SSASTGHTTP-------------------LHVT-------------DASSVST--GHATP 1008

Query: 713  SRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHP 772
              +  P+ V++G TTP PV  T  E   +      L   + S  S G     P    S  
Sbjct: 1009 LPVTSPSSVSTGHTTPLPVTDTSSE---STGHVTPLPVTSFSSASTGDSTPLPVTDTSSA 1065

Query: 773  TATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSA 832
            +   +  LP T L + +     P  + +            SS+ T HA+ +P +  TSS 
Sbjct: 1066 STGHVTPLPVTSLSSASTGDTTPLPVTD-----------TSSASTGHATSLP-VTDTSSV 1113

Query: 833  SGGPLPSCFTPSPAPILNINSASFSQGLEL----MSGFSVPKETRMYPKLSGLHRSMESL 888
            S G        +P P+ + +SAS      L     S  S    T ++   +    + ++ 
Sbjct: 1114 STG------HTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQAT 1167

Query: 889  QMPMSLPSAFPSSTPVPTPPAPPAA 913
             +P++  S+  +    P P   P++
Sbjct: 1168 PLPVTSLSSVSTGDTTPLPVTSPSS 1192



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 115/439 (26%), Positives = 168/439 (38%), Gaps = 84/439 (19%)

Query: 521  ISLGHPGSL--------KKGKTPPVAVTSPIT----HTAQSALKVAGK-PEGKATDKGKL 567
            +S GH  SL          G T P+ VTSP +    HT    +  A   P G AT    L
Sbjct: 1913 VSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATS---L 1969

Query: 568  AVKNTGLQRSSSDAGRDRLSDAKKPPSGIARP-----STSGSFGYKKPPPATGTATVMQT 622
             V +     S+  A    ++DA    +G A P     ++S S G   P P T  ++   T
Sbjct: 1970 PVTDAS-SVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSA-ST 2027

Query: 623  GGSATLSKIQKSSG-------IPVKPVN----GRKTSLDVSN--SAEPGFLAP---GARS 666
            G +  L     SS        +PV  ++    G  T L V++  SA  G   P      S
Sbjct: 2028 GDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDAS 2087

Query: 667  NIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRT 726
            ++          + + SV+ G      V+   D S LST  G  TP  +  P+  ++G T
Sbjct: 2088 SVSTGHATSLLVTDASSVSTGHATALHVT---DASSLST--GDTTPLPVTSPSSASTGDT 2142

Query: 727  TPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLR 786
            TP PV  T      +   A +L   + S  S G   S P    S  +      LP T   
Sbjct: 2143 TPLPVTDT---SSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTS 2199

Query: 787  ATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHA-TSSASGGPLPSCFTPSP 845
            + +     P  + +           PSS+ T HA  +P L   TSSAS G        +P
Sbjct: 2200 SASTGQATPLPVTS-----------PSSASTGHA--IPLLVTDTSSASTG------QATP 2240

Query: 846  APILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLP-SAFPSSTPV 904
             P+ +++SAS        +G + P        +S  H +        SLP ++  S +  
Sbjct: 2241 LPVTSLSSAS--------TGDTTPLPVTDASSVSTGHAT--------SLPVTSLSSVSTG 2284

Query: 905  PTPPAPPAAPTEEETEELT 923
             T P P  +P+   T   T
Sbjct: 2285 DTTPLPVTSPSSASTGHAT 2303



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 143/619 (23%), Positives = 227/619 (36%), Gaps = 110/619 (17%)

Query: 299  ANPRSVSSLSNRS----------SPLSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMH 348
            A P  V+SLS+ S          SP S   G ++P L   DA SV      + TP     
Sbjct: 2318 ATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATP-LHVTDASSVS---TGDTTPLPVTS 2373

Query: 349  GERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDDITT 408
               A   HT P+   +  S  S  +      +D     +G+ +   + G +     D T 
Sbjct: 2374 SSSASSGHTTPL-PVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSASTGDTTR 2432

Query: 409  -GWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTAS--RRNSTIVLRTDSEKRSL 465
                  SS S+G +     ++S    ++     LP T T+S    ++T +L TD+   S 
Sbjct: 2433 LPVTNVSSASTGHATPLP-VTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVST 2491

Query: 466  AESG-LSWFSESEEKA-----------PKKLEYDSGSLKMEPGTSKWRRERPESCDDSSK 513
             ++  L   S S               P     D+  L +   +S   R        S  
Sbjct: 2492 GDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPS 2551

Query: 514  GGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTG 573
                    S GH  SL      PV  TS  +    + L V         D   L V +T 
Sbjct: 2552 SA------STGHATSL------PVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDT- 2598

Query: 574  LQRSSSDAGRDRLSDAKKPPSGIARP-----STSGSFGYKKPPPATGTATVMQTGGSATL 628
               S+  A    ++D     +G   P     ++S S G+  P P T T++V  TG +  L
Sbjct: 2599 YSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSV-STGHATPL 2657

Query: 629  SKIQKSSG-------IPVKPVN----GRKTSLDVSNSAE---------PGFLAPGARSNI 668
                 SS        +PV   +    G  TSL V++++          P  +   A S  
Sbjct: 2658 HVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSG- 2716

Query: 669  QYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTP 728
               + P P   +S SV+ G     PV+   D S +ST  G  TP  + + + V++G  TP
Sbjct: 2717 --HTTPLPVTDAS-SVSTGHATSLPVT---DASSVST--GHATPLPVTDASSVSTGHATP 2768

Query: 729  APVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRAT 788
             P+                    ++S  S G     P    S  +  +   LP T L + 
Sbjct: 2769 LPLT-------------------SLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSV 2809

Query: 789  AKSFVKPPSLANLDKVNS-NSLDLP----SSSDTTHASKVPDLHATSSASGGPLPSCFTP 843
            +     P  + +    ++ ++  LP    SS+ T HA+ +PD   +S+++G         
Sbjct: 2810 STGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTG-------HA 2862

Query: 844  SPAPILNINSASFSQGLEL 862
            +  P+ + +SAS      L
Sbjct: 2863 TLLPVTDTSSASIGHATSL 2881



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 143/682 (20%), Positives = 242/682 (35%), Gaps = 110/682 (16%)

Query: 300  NPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMP 359
            +P SVS+      P++    +S+  +      S   +   + TP        A   H  P
Sbjct: 1013 SPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTP 1072

Query: 360  MRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDDITTGWDESSSISSG 419
            +   S LS  S  +      +D     +G+ +   +     T+   ++TG      ++  
Sbjct: 1073 LPVTS-LSSASTGDTTPLPVTDTSSASTGHATSLPV-----TDTSSVSTGHTTPLPVTDT 1126

Query: 420  LSDASDNLSSEEFNASSSLNSLPSTP-------TASRRNSTIVLRTDSEKRSLAESG--- 469
             S ++ + +S     +SS+++  +TP       +AS   +T +  T     S  ++    
Sbjct: 1127 SSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLP 1186

Query: 470  -LSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGS 528
              S  S S   A   L  D+ S      T           D SS   +    + +  P +
Sbjct: 1187 VTSPSSASTGHATPLLVTDTSSASTGHATPL------PVTDASSVSTDHATSLPVTIPSA 1240

Query: 529  LKKGKTPPVAVTSPITHTAQSA--LKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRL 586
               G T P+ VT   + +   A  L V         D   L V +T    SS+  G    
Sbjct: 1241 ASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTST----SSASTGH--- 1293

Query: 587  SDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSG-------IPV 639
                  P  +  PS S S G+  P P T  ++   TG +  L     SS        +PV
Sbjct: 1294 ----VTPLHVTSPS-SASTGHATPLPVTSLSSA-STGDTMPLPVTSPSSASTGDTTPLPV 1347

Query: 640  KPVN----GRKTSLDVSN--SAEPGFLAPGARSNIQYRSL----PRPAKSSSMSVTG--- 686
               +    G  T L V++  SA  G   P   +++   S     P P  S S + TG   
Sbjct: 1348 TDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHAT 1407

Query: 687  ------------GRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQT 734
                        G   P PV+   D S +ST      P  +  P+  ++G TTP PV  T
Sbjct: 1408 PLLVTDTSSASTGHATPLPVT---DASSVSTDHATSLPVTI--PSAASTGHTTPLPVTDT 1462

Query: 735  DREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVK 794
                       +  D+ ++S     + ++TP              LP T   + +   V 
Sbjct: 1463 SSASTGQATSLLVTDTSSVS-----TGDTTP--------------LPVTSTSSASTGHVT 1503

Query: 795  PPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFT-PSPAPILNINS 853
            P  + +           PSS+ T HA+ +P    +S+++G  +P   T PS A   +   
Sbjct: 1504 PLHVTS-----------PSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTP 1552

Query: 854  ASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAA 913
               +    + +G + P         S  H    +  +P++  S+       P P   P++
Sbjct: 1553 LPVTDASSVSTGHTTPLPVTSPSSASTGH----TTPLPVTDTSSASKGDTTPLPVTSPSS 1608

Query: 914  PTEEETEELTWSGSPRAGQLDS 935
             +   T  L  + +  A   D+
Sbjct: 1609 ASTGHTTPLPVTDTSSASTGDT 1630



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 102/465 (21%), Positives = 175/465 (37%), Gaps = 67/465 (14%)

Query: 509  DDSSKGGELKKPISLGHPGSLKKGKTPPVAVT--SPITHTAQSALKVAGKPEGKATDKGK 566
            D SS       P+ +    S+  G   P+ VT  S ++    + L V         D   
Sbjct: 1973 DASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTP 2032

Query: 567  LAVKNTGLQRSSSDAGRDR---------LSDAKKPPSGIARPSTSGSFGYKKPPPATGTA 617
            L V +T    SS+  G+D          +S     P  +  PS S S G+  P   T  +
Sbjct: 2033 LPVTDT----SSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPS-SASTGHATPLLVTDAS 2087

Query: 618  TVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRS----- 672
            +V  + G AT   +  +S +      G  T+L V++++    L+ G  + +   S     
Sbjct: 2088 SV--STGHATSLLVTDASSVST----GHATALHVTDASS---LSTGDTTPLPVTSPSSAS 2138

Query: 673  ----LPRPAKSSSMSVTGGRGGPRPVSSSIDPSL-----------LSTKQGGLTPSRLKE 717
                 P P   +S SV+ G     PV+ +   S             S   G  TP  + +
Sbjct: 2139 TGDTTPLPVTDTS-SVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTD 2197

Query: 718  PTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKL 777
             +  ++G+ TP PV         +   A+ L   + S  S G     P    S  +    
Sbjct: 2198 TSSASTGQATPLPVTS---PSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDT 2254

Query: 778  AELPPTPLRATAKSFVKPPSLANLDKVNSNS-----LDLPSSSDTTHASKVPDLHATSSA 832
              LP T   + +        + +L  V++       +  PSS+ T HA+    LH T ++
Sbjct: 2255 TPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHAT---PLHVTDAS 2311

Query: 833  SGGPLPSCFTPSPAPILNINSASFSQGLEL----MSGFSVPKETRMYPKLSGLHRSMESL 888
            S     S    +P P+ +++SAS      L     S  S    T ++   +    + ++ 
Sbjct: 2312 SA----STGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTT 2367

Query: 889  QMPMSLPSAFPS--STPVPTPPAPPAAPTEEETEELTWSGSPRAG 931
             +P++  S+  S  +TP+P   A  A+  +     +T + S   G
Sbjct: 2368 PLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTG 2412



 Score = 35.0 bits (79), Expect = 0.69
 Identities = 119/637 (18%), Positives = 215/637 (33%), Gaps = 57/637 (8%)

Query: 704  STKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPES 763
            +T+   +T S+   P   ++G TT     Q+     +   + ++  S N   KS    E+
Sbjct: 29   TTEDTLITGSKTAAPV-TSTGSTTATLEGQSTAASSRTSNQDISASSQNHQTKST---ET 84

Query: 764  TPKNQA------------SHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDL 811
            T K Q             S P+   + E  P     T  SF  P S+ N   + S ++ +
Sbjct: 85   TSKAQTDTLTQMMTSTLFSSPSVHNVMETAPPDEMTT--SF--PSSVTNTLMMTSKTITM 140

Query: 812  PSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKE 871
             +S+D+T      +     + S  P+ S  + +        + S+   ++  S  S    
Sbjct: 141  TTSTDST-LGNTEETSTAGTESSTPVTSAVSITAGQEGQSRTTSWRTSIQDTSASSQNHW 199

Query: 872  TRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEE----LTWSGS 927
            TR   + +   ++        S PS  PS   V    +   +P+ E        +T +  
Sbjct: 200  TRS-TQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSVTNTSM 258

Query: 928  PRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPALPM 987
              + ++       +TL   G    +           +  +   PE    +          
Sbjct: 259  MTSEKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDPEGQSPATFSRTSTQDT 318

Query: 988  SLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSG 1047
            +  +K   T  V  T  +      + +  T        SG     T+S    P G   + 
Sbjct: 319  TAFSKNHQTQSVETTRVSQINTLNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTTS 378

Query: 1048 SFRDPTDD--VHGSVLSLASSASSTYSSAEERMQSEQ--IRKLRRELESS--QEKVATLT 1101
            S    ++   V   V  + +S  ST  + EE   S    I  +  ++ +    + ++T  
Sbjct: 379  SPSSVSNTFLVTSKVFRMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTAL 438

Query: 1102 SQLSANANLVAAF---EQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQA 1158
            S  S    +  AF   +      T R    +  +     E+  L ET  +    +S+   
Sbjct: 439  SPSSLPPKISTAFHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHT 498

Query: 1159 VIQGALNASETTPKELRIKRQNSS--------------DSISSLNSITSHSSIGSSKDAD 1204
                    S +T    R+   N S               +I      T++SS  ++    
Sbjct: 499  TWSQTELPSTSTGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKT 558

Query: 1205 AKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTE--TAS 1262
                 +  W + +     ++   P    SYS  + I T  S + SSP L   +++  T +
Sbjct: 559  TGAGAQTQWTQETGTTGEALLSSP----SYSVTQMIKTATSPS-SSPMLDRHTSQQITTA 613

Query: 1263 PSIKSSTSSSVGTDVTEGPA-HPAPHTRLFHANEEEE 1298
            PS   ST  S  T   E PA     HT+     +E +
Sbjct: 614  PSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQ 650


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 263/1242 (21%), Positives = 425/1242 (34%), Gaps = 167/1242 (13%)

Query: 124  KVGSKGREAPLMSKTLSKSEHSLFQAKGSPAGGAKTPLAPLAPNLGKPSRIPRGPYA--E 181
            +V SK R +P  S++ S  E    + + +P   + +  +P  P    P  +PR   +   
Sbjct: 1584 EVDSKSRLSPRRSRSGSSPEVK-DKPRAAPRAQSGSDSSP-EPKAPAPRALPRRSRSGSS 1641

Query: 182  VKPLSKAPEAAVSEDGKSDDELLSSKAKAQKSSGPVPSAKGQE--ERAFLKVDPELVVTV 239
             K    +PE + S +   +    S  A+    S P P  K +    R   +  PEL  T 
Sbjct: 1642 SKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPEL--TR 1699

Query: 240  LGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMTCYDSDDA 299
               L +   S    PE+ R RT       R     ++SS   ++ + SS           
Sbjct: 1700 KARLSRRSRSASSSPET-RSRTPP-----RHRRSPSVSSPEPAEKSRSSRRR-------- 1745

Query: 300  NPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMP 359
              RS SS   +++    R     PR          G  RS           R   + T  
Sbjct: 1746 --RSASSPRTKTTSRRGRSPSPKPR----------GLQRSRSR-------SRREKTRTTR 1786

Query: 360  MRSPSKLSHISRLELVESLDSDEVDLK----SGYMSDSDLMGKTMTEDDDITTGWDESSS 415
             R  S  S  +      S     V  +    SGY S S    ++         G   +  
Sbjct: 1787 RRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPP 1846

Query: 416  IS-----SGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGL 470
             S     S  S A    S    + ++   S   TP  SRR S       S +RS + + +
Sbjct: 1847 TSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSV 1906

Query: 471  SWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLK 530
            +        +P        S    P  ++ RR R  +     +      P++        
Sbjct: 1907 TRRRSRSRASPVSRRR---SRSRTPPVTR-RRSRSRTPTTRRRSRSRTPPVTRRR----S 1958

Query: 531  KGKTPPV------AVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRD 584
            + +TPPV      + TSPIT     +      P  +   + + +       RS +     
Sbjct: 1959 RSRTPPVTRRRSRSRTSPITRRRSRSRT---SPVTRRRSRSRTSPVTRRRSRSRTSPVTR 2015

Query: 585  RLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNG 644
            R S ++ PP+   R  +      +K   +     + +   S T    +    +   P   
Sbjct: 2016 RRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAI 2075

Query: 645  RK-----TSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRG-GPRPVSSSI 698
            R+     +S D S SA P    P  R++   R+ P    SS MS        P P+    
Sbjct: 2076 RRRSASGSSSDRSRSATP----PATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCR 2131

Query: 699  DPSLLSTKQGGLTPSRLKEPT--KVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLK 756
             P +L       TP  + +     +  G     P +Q     E      +AL    ISL 
Sbjct: 2132 SPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLG 2191

Query: 757  SIGSPESTPKNQASHPTATKLAELP-PTPLR-------ATAKSFVKPPSLANLDKVNSNS 808
            +   P S     ++   A +++++P P PL        A   S +   S A ++  ++ +
Sbjct: 2192 TARPPPS----MSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASART 2247

Query: 809  LDLPSS-----SDTTHASKVPDLHATSSA---SGGPLPSCFTPSPAPILNINSASFSQGL 860
              +P++     S T  A+   +L +  +A   S   L    TP+ AP +N+  A     L
Sbjct: 2248 PAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPT-APAVNLAGARTPAAL 2306

Query: 861  ELMS--GFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEE 918
              +S  G   P     YP       S  + Q P S     P S     P     + T   
Sbjct: 2307 AALSLTGSGTPPTAANYPS------SSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAA 2360

Query: 919  TEELTWSGSPRAGQLDSNQRDRNTLPKKGL-RYQLQSQEETKERRHSHTIGGLPESDDQS 977
                + + +  A  L         +P     R   ++     +R  S T    P +  QS
Sbjct: 2361 LAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTP---PSAPSQS 2417

Query: 978  ELPSPPALPMSLSAKGQL-TNIVSPTAATTPRITRSNSIP----------THEAAFELYS 1026
             + S  A P   S  GQ  +  + P A   PR    ++            T  A  +  S
Sbjct: 2418 RMTSERA-PSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLS 2476

Query: 1027 GSQMGSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKL 1086
               + +T S A    GM+   +   P  DV           +ST +     + + Q  K 
Sbjct: 2477 SGAVATTTSSAGDHNGMLSVPAPGVPHSDV-------GEPPASTGAQQPSALAALQPAKE 2529

Query: 1087 RRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETI 1146
            RR   SS    ++ +S  S++++  ++   S  +  S L    E A              
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVA-------------- 2575

Query: 1147 DFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAK 1206
              LK+  S   A  +         P   + KR++SS S SS +S +S SS  SS  + + 
Sbjct: 2576 --LKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS 2633

Query: 1207 KKKKKSWLRSSFNKAFS-IKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASP-- 1263
                 S   SS + + S  K GP+           A P  ++P  P    G   + SP  
Sbjct: 2634 SSSSSSSSSSSSSSSPSPAKPGPQ-----------ALPKPASPKKP--PPGERRSRSPRK 2680

Query: 1264 ---SIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKK 1302
               S++ S S S        P+ P P  R   ++  E   ++
Sbjct: 2681 PIDSLRDSRSLSYSPVERRRPS-PQPSPRDQQSSSSERGSRR 2721



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 109/459 (23%), Positives = 172/459 (37%), Gaps = 77/459 (16%)

Query: 369  ISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDDITTGWDESSSISSGLSDASDNLS 428
            +++LE   SLD  E   +S   S S+L    + +      G   + SISS + DA     
Sbjct: 1360 LNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEK-----AGMSSNQSISSPVLDAVPRTP 1414

Query: 429  SEEFNASSS----LNSLPSTPT-ASRRNSTIVLRTDS---EKRSLAESGLSWFSESEEKA 480
            S E ++S+S     + LP TP+  SR  S+  LR  S    + SL+ S           +
Sbjct: 1415 SRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPS 1474

Query: 481  PKKLEYDSG-SLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAV 539
              + E DS    K  P T + R   P S                  P    K  TP    
Sbjct: 1475 RGRSECDSSPEPKALPQTPRPRSRSPSS------------------PELNNKCLTPQRER 1516

Query: 540  TSPITHTAQSALKVAGKPEGKATDKG---KLAVKNTG--LQRSSSDAGRDRLSDAKKPPS 594
            +   +   Q    VA  P G+ +  G   +L VK +    +RS SD+  D  +  + P  
Sbjct: 1517 SGSESSVDQKT--VARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTP-- 1572

Query: 595  GIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNS 654
             + + S SGS      P     + +     S   S+   S  +  KP    +      +S
Sbjct: 1573 -LRQRSRSGS-----SPEVDSKSRL-----SPRRSRSGSSPEVKDKPRAAPRAQSGSDSS 1621

Query: 655  AEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSID------PSLLSTKQG 708
             EP   AP        R+LPR ++S S S   GRG     SSS +      P   + ++G
Sbjct: 1622 PEPKAPAP--------RALPRRSRSGSSS--KGRGPSPEGSSSTESSPEHPPKSRTARRG 1671

Query: 709  GLT----PSRLKEPTKVASGRTTP-----APVNQTDREKEKAKAKAVALDSDNISLKSIG 759
              +     ++ + P +  S R++P     A +++  R    +          +    S+ 
Sbjct: 1672 SRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVS 1731

Query: 760  SPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSL 798
            SPE   K+++S    +  +    T  R       KP  L
Sbjct: 1732 SPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGL 1770



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 234/1140 (20%), Positives = 374/1140 (32%), Gaps = 176/1140 (15%)

Query: 60   SAAELKVFKSGSVDSRVPGGPPASNLRKQKSLTNLSFLTDSEKKLQLYEPEWSDDMAKAP 119
            S+ E+K  +  S  SR    P +    +     +LS  +   K+     P  S   +  P
Sbjct: 745  SSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQP 804

Query: 120  KGLGKVG---SKGREAP---LMSKTLSKSEHSLFQAKGSPAGGAKTPLAPLAPNLGKPSR 173
            K   +     S+   +P     SKT S+  HS      SP    K+   P   ++  P  
Sbjct: 805  KAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHS----SSSPHPKVKSGTPPRQGSITSP-- 858

Query: 174  IPRGPYAEVKPLSKAPEAAVSEDGKSDDELLSSKAKAQKSSGPVPSAKGQEERAFLKVDP 233
                   +    S  P+     +   D EL S        SG  P       R      P
Sbjct: 859  -------QANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPP------RVKSSTPP 905

Query: 234  ELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMTC 293
                            Q     S  +  V+ ++  RQ      SS   S+VT  +     
Sbjct: 906  R---------------QSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR-- 948

Query: 294  YDSDDANPRSVSSLSNRSSPLSWRYGQSS-------------PRLQAGDAPSVGGSCRSE 340
                    RSVS  SN  S L  RY  S              PR     + S     +++
Sbjct: 949  ------RSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQ 1002

Query: 341  GTPAWYMHGERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGY-MSDSDLMGKT 399
              P   + G ++         S  + S    L L   + S     +S + +S   L G++
Sbjct: 1003 TPPGPSLSGSKSPCPQEKSKDSLVQ-SCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQS 1061

Query: 400  MTEDDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTD 459
             T  D  +         S   S +  + S        S +S P T  ASR      +R D
Sbjct: 1062 QTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSP----IRQD 1117

Query: 460  SEKRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKK 519
              + S +    S  S  + +     + DS S       S   + R E+ +   K     +
Sbjct: 1118 RGEFSASPMLKSGMSPEQSR----FQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQ 1173

Query: 520  PISLGHPGSLKKGKTP-PVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSS 578
              +   P   K   +P PV      +   +  L+   +    A    +   +N+ L  SS
Sbjct: 1174 EDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSS 1233

Query: 579  SDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGG-SATLSKIQKSSGI 637
             D     + +  + P+G      S             +  V +    S TL + Q  + +
Sbjct: 1234 QDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASL 1293

Query: 638  PVKPVNGRKTSL----------DVSNSA--EPGFLAPGARSNIQYR-SLPRPAKSS---S 681
                V    +S           ++SNS   E  F +P     +++R S P   + +   S
Sbjct: 1294 EAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSP-----LEFRNSGPLGTEMNTGFS 1348

Query: 682  MSVTGGRGGPRPVSSSIDPSL----LSTKQGGLTPSRLK----EPTKVASGRTTPAPV-- 731
              V     GP       DPSL     ST+  G + S L     E   ++S ++  +PV  
Sbjct: 1349 SEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLD 1408

Query: 732  ---NQTDREKEKAKAKAVALD---------SDNISLKSIGSPESTPKNQASHPTATKLAE 779
                   RE+  + +     D         S + S   +     TP   +   ++  + +
Sbjct: 1409 AVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKD 1468

Query: 780  LPPTPLRATAK--SFVKPPSLANLDKVNSNSLDLP-----------------SSSDTTHA 820
            +P TP R  ++  S  +P +L    +  S S   P                 SS D    
Sbjct: 1469 IPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTV 1528

Query: 821  SKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGL-------ELMSGFS--VPKE 871
            ++ P    + S S   L    + SP      +S+  S+            SG S  V  +
Sbjct: 1529 ARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSK 1588

Query: 872  TRMYPKLSGLHRSMESLQMPMSLPSAFPSS--TPVPTPPAPPAAPTEEETEELTWSGSPR 929
            +R+ P+ S    S E    P + P A   S  +P P  PAP A               PR
Sbjct: 1589 SRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRAL--------------PR 1634

Query: 930  AGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELP-------SP 982
              +  S+ + R   P+     +   +   K R         PE   +S  P       S 
Sbjct: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSS 1694

Query: 983  PALPMS--LSAKGQLTNIVSPT-AATTPRITRSNSIPTHEAAFELYSGSQMGSTLSLAER 1039
            P L     LS + +  +    T + T PR  RS S+ + E A +  S  +  S    A  
Sbjct: 1695 PELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRS----ASS 1750

Query: 1040 PKGMIRSGSFRDPTDDVHGSVLSLASS--ASSTYSSAEERMQSEQIRKLRRELESSQEKV 1097
            P+    S   R P+    G   S + S    +  +   +R  S Q    RR+   S+ +V
Sbjct: 1751 PRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRV 1810



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 87/364 (23%), Positives = 128/364 (35%), Gaps = 59/364 (16%)

Query: 711  TPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQAS 770
            TP + K+  K   GR + +   + +R+K   K K  + +S++   K   SP    K ++ 
Sbjct: 184  TPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRS-ESESKKRKH-RSPTPKSKRKSK 241

Query: 771  HPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHA---SKVPDLH 827
                 +     P P    A                S S D  SSSDT+ +   S     H
Sbjct: 242  DKKRKRSRSTTPAPKSRRAH--------------RSTSADSASSSDTSRSRSRSAAAKTH 287

Query: 828  ATSSASGGPLPSCFTPSPAPILNINSASFSQ-GLELMSGFSVPKETRMYPKLSGLHRSME 886
             T+ A   P P+              A FS+ G       S P+     P      +  +
Sbjct: 288  TTALAGRSPSPASGRRGE------GDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKD 341

Query: 887  SLQMPMSLPSAFPS-STPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPK 945
              +   + PS  P  S+  P PPAP     E         GSP+        ++    P 
Sbjct: 342  KKEKSATRPSPSPERSSTGPEPPAPTPLLAERH------GGSPQPLATTPLSQEPVNPPS 395

Query: 946  KGLRYQLQSQEETKERRHSHTIGGLPE-SDDQSELPSPPALPMSLSAKGQLTNIVSPTAA 1004
            +           T++R    +   LP+ S  +S  PSP    +S  A    ++  SP  A
Sbjct: 396  EA--------SPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHAS---SSPESPKPA 444

Query: 1005 TTPRITRS-NSIPT-----HEAAFELYSGS-----QMGSTLSLAERPKGMIRSGSFRDPT 1053
              P   R  +S PT     H  A    S S     +MG + S A   +G  RS   R PT
Sbjct: 445  PAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRS---RTPT 501

Query: 1054 DDVH 1057
               H
Sbjct: 502  KRGH 505


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 111/449 (24%), Positives = 171/449 (38%), Gaps = 54/449 (12%)

Query: 496 GTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKK-GKTPPVAVTSPITHTAQSALKVA 554
           GTS      P S   +S  GE   P     PG +   G+        P+    Q  L+++
Sbjct: 84  GTSS---RNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL---GQKGLRIS 137

Query: 555 GKP---EGKATDKGKLAVKNTGLQRSSS-------DAGRDRLSDAKKPPSGIARPSTSGS 604
            +     GKAT+  K +  + G +R +S            R S A     G+ RP+ S  
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA- 196

Query: 605 FGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNG----RKTSLDVSNSAEPGFL 660
              +  PP  G    + +      S  + S     +P  G    R  S  +S+SA P  L
Sbjct: 197 ---RPRPPTEGPRKSVSSASEH--STTEPSPAARRRPSAGGGLQRPASRSLSSSATP--L 249

Query: 661 APGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTK 720
           +  ARS    R  PR     S     G    RP   +      +   G L+ S L  P+ 
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309

Query: 721 VASGR-----TTPAPVNQTDREKEKAKAKAVALDSDNI--SLKSIGSPESTPKNQASHPT 773
            A+ +     T PA  + +    + A    +A  S +   SL+++ SP +TP +QA+   
Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369

Query: 774 ATKLAE-----LPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHA 828
            +   +     LP  PL   A    + P    L  + +     P +S        P   A
Sbjct: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS--PPASPPLSPLATPSPQA 427

Query: 829 TSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESL 888
            ++ +   L + F+P P+P +    A FS         S    ++  P L+        L
Sbjct: 428 PNALAVHLLQAPFSPPPSPPVQ---APFSPPASPPVSPSATPPSQAPPSLAA-----PPL 479

Query: 889 QMPMSLPSA---FPSSTPVPTPPAPPAAP 914
           Q+P S P++    PS+TP P  P P AAP
Sbjct: 480 QVPPSPPASPPMSPSATPPPQAPPPLAAP 508



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 98/428 (22%), Positives = 141/428 (32%), Gaps = 70/428 (16%)

Query: 525 HPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRD 584
           H  SL      P+ +  P + +A  +L+    P      +   ++ +  LQ + S     
Sbjct: 326 HSSSLTCQLATPLPLAPP-SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 384

Query: 585 RLSDAKKPPS----GIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKS--SGIP 638
            LS    PP      +A P           PP +  AT      +A    + ++  S  P
Sbjct: 385 PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 444

Query: 639 VKPVNGR---KTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMS--VTGGRGGPRP 693
             PV        S  VS SA P   AP + +    +  P P  S  MS   T     P P
Sbjct: 445 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504

Query: 694 VSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNI 753
           +++   P L   K     P  L  P   A     P+P          A     A  S + 
Sbjct: 505 LAA---PPLQLAKPPPQAPPALATPPLQA----LPSP---------PASFPGQAPFSPSA 548

Query: 754 SLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPS 813
           SL    SP +TP  QA    A  L ++PP+P                           P+
Sbjct: 549 SLPM--SPLATPPPQAPPVLAAPLLQVPPSP---------------------------PA 579

Query: 814 SSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLEL----MSGFSVP 869
           S       + P     +S SG  L     P P P  + + +S   G +L     S  S P
Sbjct: 580 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 639

Query: 870 KETRMY---PKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSG 926
           +E R Y   P+           ++    P+A+         PAPP A        L W  
Sbjct: 640 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG------PAPPLAFRGAPGAPLPWPP 693

Query: 927 SPRAGQLD 934
           +   G  D
Sbjct: 694 ATGPGSAD 701


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 101/427 (23%), Positives = 136/427 (31%), Gaps = 80/427 (18%)

Query: 511  SSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKA-TDKGKLAV 569
            S KGG    P          KG   P A T P    +       G P   A T       
Sbjct: 1296 SPKGGPATSP---------PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGT 1346

Query: 570  KNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLS 629
                    SS  G    S  + P    A PS  G      P P  G A     G   +  
Sbjct: 1347 PTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS-- 1404

Query: 630  KIQKSSGIPVKPVNGRKTSLDVSNSAEP--GFLAPGARSNIQYRSLPRPAKSSSMSVTGG 687
                 + IP+ P     T +    +A P  G L P A + +  +  P        + +  
Sbjct: 1405 ----PAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAP--------ATSAP 1452

Query: 688  RGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVN-QTDREKEKAKAKAV 746
            +GGP   SS  DP+L +     +TP   KEP         PAP    T    +KA A   
Sbjct: 1453 KGGPATPSSKGDPTLPA-----VTPPSPKEP---------PAPKQVATSSSPKKAPATPA 1498

Query: 747  ALDSDNISLKSIGSPESTPKNQASH-----PTATKLAELPPTPLRATAKSFVKPPSLANL 801
             + +  +      SP+  P   +S      PTAT L++   TP     K  + PP++   
Sbjct: 1499 PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSK--KTPATLAPKEALIPPAMT-- 1554

Query: 802  DKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLE 861
                     +PS   T       +  AT S+     P   TPS                 
Sbjct: 1555 ---------VPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPS----------------- 1588

Query: 862  LMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEE 921
               G   PKE  + P ++    S    + P       PS    P  PAP   PT      
Sbjct: 1589 TYKGAPSPKELLIPPAVT----SPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTP 1644

Query: 922  LTWSGSP 928
             +   SP
Sbjct: 1645 SSLKDSP 1651



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 148/622 (23%), Positives = 205/622 (32%), Gaps = 62/622 (9%)

Query: 442  PSTPTASRRNSTIVLRTDSEKRSLAESGLSWF--SESEEKAPKKLEYDSGSLKMEPGTS- 498
            P+TP A ++   + + + S K++ A         S S + AP        S K  P T  
Sbjct: 900  PATP-APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS 958

Query: 499  -KWRRERPESCDDSSKGGELKK-------------PISLGHPGSLK-KGKTPPVAVTSPI 543
             KW    P +   S KGG                 P   G P +   KG   P AVT P 
Sbjct: 959  PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018

Query: 544  THTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSG 603
               + +A      P+G +T          G   ++        + A   PS    P+T  
Sbjct: 1019 PKGSPAATPF---PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPS 1075

Query: 604  SFGYKKPPPATGTATVMQTGGSATLSKI---QKSSGIPVKPVNGRKTSLDVSNSAEPGFL 660
              G   PP AT  +     GG AT S        +  P  P  G  T         P   
Sbjct: 1076 LKGAPTPPAATPPSP---KGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAAT 1132

Query: 661  APGARSNIQY---RSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLL--STKQGGLTPSRL 715
             P  +  +     +  P    ++  S  GG   P P  +   P+    S K G  TPS  
Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPK 1192

Query: 716  KEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTAT 775
              PT  A+   +P     T   K      A    S    L +  SP+  P   A+ P + 
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT-PSPKGAPTTPAATPPSP 1251

Query: 776  KLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGG 835
            K     P P  A       PPSL             P+ +  T  S      ATS   G 
Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKG-GLATPPHKGAPNPAVVTPPSPKGG-PATSPPKGA 1309

Query: 836  PLPSCFTP--------SPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMES 887
            P P   TP        +P P      A     +   S    P      P   G   +  S
Sbjct: 1310 PTPPAATPPSPKGSPGTPPP----KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365

Query: 888  LQMPMSLPSAFPS--STPVPTPPAP---PAAPTE--EETEELTWSGSPRAGQLDSNQRDR 940
             + P + P+A PS    P  TPP+P   PA P+   + T       SP+        R+ 
Sbjct: 1366 KEGP-TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREG 1424

Query: 941  NTLPKKG-LRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPAL----PMSLSAKGQL 995
               P KG L     +    K+   +    G P +      P+ PA+    P    A  Q+
Sbjct: 1425 AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484

Query: 996  TNIVSP-TAATTPRITRSNSIP 1016
                SP  A  TP    + ++P
Sbjct: 1485 ATSSSPKKAPATPAPMGAPTLP 1506



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 106/485 (21%), Positives = 169/485 (34%), Gaps = 76/485 (15%)

Query: 573  GLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQ 632
            G   S + AG     D    P   A P  S SF       +T ++  +     ATL+K  
Sbjct: 541  GAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSF------QSTSSSPEIPLSPEATLAKKS 594

Query: 633  KSSGIPV-KPVNGRKTSLDVSNSAE----PGFLAPGARSNIQYRSLPRPAKSSSMSVTGG 687
                +P+ KP +   + L V++SA       +  P +   +   SL  P  ++    +  
Sbjct: 595  LGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESAD 654

Query: 688  RGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVA 747
              G  P          +T +G  T +    P     G  + AP N   +E        V 
Sbjct: 655  PAGVAP----------TTAKGTSTYTTTASP--FLEGTVSLAPKNHPVKEGTLTTLPLVP 702

Query: 748  LDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSN 807
              S+N  +    SP++T    A+   A ++ +  P+P    A +   PP    +D ++  
Sbjct: 703  TASENCPVAP--SPQNTCAPLATLVLAPEIPKSVPSPSLPPAGT---PPGTKKVDGISHT 757

Query: 808  SLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFS 867
            S   P +S         D  A+++AS     +    SP+P+                G S
Sbjct: 758  SALAPVASSPKECP-TEDSGASATASSKGTLTYLADSPSPL----------------GVS 800

Query: 868  VPKETRMYPKLSGL---HRSMESLQMPMSLPSAF---------------PSSTPVPTPPA 909
            V  +T+  P   G       + +L  P+S   A                P++T  PTPP+
Sbjct: 801  VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860

Query: 910  PPAAPTEEETEELTWSG---------SPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKE 960
            P  APT      L+  G         +P    L   +    T   K       +    K+
Sbjct: 861  PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920

Query: 961  RRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTN----IVSPTAATTPRITRSNSIP 1016
             R +    G+P S      P+PPA        G  T       +P AAT P      + P
Sbjct: 921  ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP 980

Query: 1017 THEAA 1021
            + + A
Sbjct: 981  SPKGA 985



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 139/598 (23%), Positives = 198/598 (33%), Gaps = 119/598 (19%)

Query: 505  PESCDDSSKGGELKKP------ISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAG--- 555
            P +   S KGG    P           P S K G   P    +P T  A       G   
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188

Query: 556  -KPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPS---GIARPSTSGSFGYKKPP 611
              P+G  T          G   + S  G    + A  PPS   G+A PS  G+       
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPT-TPAATPPSPKGGLATPSPKGA------- 1240

Query: 612  PATGTATVMQT-GGSATLSKIQKSSGIPVKP------VNGRKTSLDVSNSAEPGFLAP-- 662
            P T  AT     GG AT        G P  P      + G   +     +  P  + P  
Sbjct: 1241 PTTPAATPPSPKGGPAT----PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPS 1296

Query: 663  --GARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGL------TPSR 714
              G  +    +  P P  ++  S  G  G P P  +   P++      G       TPS 
Sbjct: 1297 PKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS 1356

Query: 715  LKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTA 774
               PT   S +  P P   T   K      A+   S      +I SP+  P + A  P +
Sbjct: 1357 KGGPT-TPSSKEGPTPPAATPSHKG---GPAMTPPSPKRG-PAIPSPKGDPTSPAVIPLS 1411

Query: 775  TKLAELPPTPLRATA---KSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKV-PDLHATS 830
             K A   P      A   K  + PP++  +    + +   P     T +SK  P L A +
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471

Query: 831  -------------SASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFS------VPKE 871
                         + S  P  +  TP+P     + +   S   E+ +  S       P  
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531

Query: 872  TRMYPKLSGLHRSMESLQMP-MSLPSAFPSSTP-VPTPPAPPAAPTEEETEE------LT 923
            T +  K        E+L  P M++PS  P  TP +PTP   PA P+ +E          T
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPS--PKKTPAIPTPKEAPATPSSKEASSPPAVTPST 1589

Query: 924  WSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPP 983
            + G+P   +L                                 I     S    E P+PP
Sbjct: 1590 YKGAPSPKEL--------------------------------LIPPAVTSPSPKEAPTPP 1617

Query: 984  ALPMSLSAKGQLTNIVSPTAATTPRITRSN--SIPTHEAAFELYSGSQMGSTLSLAER 1039
            A+      KG  T     T  T+P +T S+    PT  A+       +MG+T+  A +
Sbjct: 1618 AVTPPSPEKGPATPAPKGT-PTSPPVTPSSLKDSPTSPASVT----CKMGATVPQASK 1670



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 128/548 (23%), Positives = 176/548 (32%), Gaps = 111/548 (20%)

Query: 520  PISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKN-----TGL 574
            P S+  P     G  P       I+HT+  A   +   E    D G  A  +     T L
Sbjct: 731  PKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYL 790

Query: 575  QRSSSDAGRDRLSDAKKPPS--GIARPST--------------------SGSF-GYKKPP 611
              S S  G       K+PP+  G A P T                    S SF G K  P
Sbjct: 791  ADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSP 850

Query: 612  PATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYR 671
              T + T     G+ T S         V P++ +  +L    +  P  +      N+ + 
Sbjct: 851  ATTHSPTPPSPKGAPTPSA--------VTPLSPKGVTLPPKETPTPSVV------NLPFP 896

Query: 672  ----SLPRPAKSSSMSVTGG-----RGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVA 722
                + P P ++ ++S+T       R  P P      PS     +G  TP     P+   
Sbjct: 897  KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPS----PKGAPTPPAATPPSP-K 951

Query: 723  SGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPP 782
             G  TP+P        + A     A         +  SP+  P   A+ P + K     P
Sbjct: 952  GGPATPSP--------KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003

Query: 783  TPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFT 842
            +P  A     V PPS     K +  +   P  + T  A+  P    + +A+  PLP    
Sbjct: 1004 SPKGAPTPPAVTPPS----PKGSPAATPFPKGASTPPAATPPSPKGSPAAT--PLPKGAP 1057

Query: 843  PSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSS- 901
             +PA  L       +    L    + P  T   PK      S +   MP   P+A P S 
Sbjct: 1058 TTPAATLPSPKGGPATP-SLKGAPTPPAATPPSPKGGPATPSPKGAPMP---PAATPPSP 1113

Query: 902  --------------TPVPTPPAPPAA-----PTEEETEELTWSGSPRAGQLDSNQRDRNT 942
                          TP  TPP+P        P    T       SP+ G          T
Sbjct: 1114 KGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA--------T 1165

Query: 943  LPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSPT 1002
             P KG          T         GGL     +    +P A P   S KG L       
Sbjct: 1166 PPPKG-------APTTPAATPPSPKGGLATPSPKGAPTTPAATPP--SPKGGLATPSPKG 1216

Query: 1003 AATTPRIT 1010
            A TTP  T
Sbjct: 1217 APTTPAAT 1224



 Score = 38.9 bits (89), Expect = 0.048
 Identities = 114/527 (21%), Positives = 167/527 (31%), Gaps = 69/527 (13%)

Query: 490  SLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQS 549
            SLK  P TS     +      SSKG      ++   P S K+   P    TS     A +
Sbjct: 1442 SLKKAPATSA---PKGGPATPSSKGDPTLPAVT---PPSPKEPPAPKQVATSSSPKKAPA 1495

Query: 550  ALKVAGKPEGKAT-DKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYK 608
                 G P   A        V  T   R    A    L  +KK P+ +A           
Sbjct: 1496 TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLL-SKKTPATLAPKEALIPPAMT 1554

Query: 609  KPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNI 668
             P P    A        AT S  + SS   V P      S      +    L P A ++ 
Sbjct: 1555 VPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP------STYKGAPSPKELLIPPAVTSP 1608

Query: 669  QYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKE-PTKVAS---- 723
              +  P P   +  S   G   P P  +   P +        TPS LK+ PT  AS    
Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPV--------TPSSLKDSPTSPASVTCK 1660

Query: 724  -GRTTPAPVNQTDREKEKAKAKAVAL---------------DSDNISLKSIGSPESTPKN 767
             G T P        +K     K V +                       S  SP   P  
Sbjct: 1661 MGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDP 1720

Query: 768  QASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKV---- 823
             A + +   L+ + P PL    K   K     +        L  P S  +T  +      
Sbjct: 1721 SAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEK 1780

Query: 824  ----PDLHATSSASGGPLPSCFTPSPAPILNINSASF--SQGLELMS---GFSVPKETRM 874
                P+  + S+A   P+     PSP P L         S GL L S     +   E  +
Sbjct: 1781 VLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDEL 1840

Query: 875  YPKL--SGLHRSMESLQMPMSLPSAFPSSTPVPTPPAP-----------PAAPTEEETEE 921
             P +    +   +    + +++P+   +  PVPTP A              + ++E   E
Sbjct: 1841 LPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPE 1900

Query: 922  LTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIG 968
            L    S +A    +       + ++ +    QS+ E K R+    +G
Sbjct: 1901 LEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLG 1947


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 221/1055 (20%), Positives = 377/1055 (35%), Gaps = 140/1055 (13%)

Query: 415  SISSGL-SDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLA-----ES 468
            S +SGL  +++ +  S     +++L   P+TP+ S +++T      S   +L+      S
Sbjct: 4043 STTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 4102

Query: 469  GLSWFSESEEKAPKKL-------EYDSGSLKMEPGTSKWRRERPES--CDDSSKGGELKK 519
            G+S  S +    P             +  L  EP TS   +   E+     S+    L +
Sbjct: 4103 GVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQ 4162

Query: 520  PISLGH--PGSLKKGKTPPVAVTSPI------THTAQSALKVAGKPEGKATDKGKLAVKN 571
              +  H  PG  +    P   +TS +      TH++  +L     P             +
Sbjct: 4163 QSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASST---------S 4213

Query: 572  TGLQRSSS--DAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLS 629
            TGLQ  S+   +          PPS  A P    +  + +P   + T T   +  S TL 
Sbjct: 4214 TGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRP---SSTPTTHFSASSTTLG 4270

Query: 630  KIQKSSGIPVKPVNGRKTSLDVSNSA------EPGFLAPGARSNIQYRSLPRPAKSSSMS 683
            + ++S+ +   P     T+L  + SA      EP   +P +  + +  +LP    ++ +S
Sbjct: 4271 RSEESTTVHSSP-GATGTALFPTRSATSVLVGEP-TTSPISSGSTETTALPGSTTTAGLS 4328

Query: 684  --VTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQT----DRE 737
               T     PR   +++ P+  ST   G++       ++  S  TT  P + T     +E
Sbjct: 4329 EKSTTFYSSPRSPDTTLSPA--STTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQE 4386

Query: 738  KEKAKAKAVALDS----DNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFV 793
               + +   + D+     + +  S+G PEST  + +   T T L      P   TA   +
Sbjct: 4387 STASHSSPGSTDTTLSPGSTTASSLG-PESTTFHSSPGSTETTL-----LPDNTTASGLL 4440

Query: 794  KPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINS 853
            +  +  +    + ++   P+ S T            +S    P P   T +   +   + 
Sbjct: 4441 EASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSH 4500

Query: 854  ASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPV--PTPPAPP 911
             S S         S P            H S  S  +  S  S    S+PV   T P+P 
Sbjct: 4501 GSPS---------STPT----------THFSASSTTLGRSEESTTVHSSPVATATTPSPA 4541

Query: 912  AAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLP 971
             + T    EE T   S        +  + NT   +G       +  T     +HTI   P
Sbjct: 4542 RSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRG------EESTTSHSSTTHTISSAP 4595

Query: 972  ESDDQSELPSPPALPMSLSAKGQLTNI--VSPTAATTPRITRSNSIPTHEAAFELYSGSQ 1029
             +   S L   P    S       T+    S T+  +   T S+S  + +A   +   ++
Sbjct: 4596 ST--TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHS--SQDATGTIVLPAR 4651

Query: 1030 MGSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLA-SSASSTYSSAEERMQSEQIRKLRR 1088
              +++ L E     I SGS    T  + GS  +   S  S+T+ S+     +        
Sbjct: 4652 STTSVLLGESTTSPISSGSME--TTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASST 4709

Query: 1089 ELESSQEK-------VATLTSQLSANANLVAAFEQSLVNMTS----RLRHLAET------ 1131
             L  S+E        VAT T+   A +      E+S    +S    +  H  E+      
Sbjct: 4710 TLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGR 4769

Query: 1132 AEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKR--QNSSDSISSLN 1189
            +EE  T       TI       S   A+++    +  ++P  +      ++S+ S  S  
Sbjct: 4770 SEESRTSHSSTTHTI---SSPPSTTSALVEEP-TSYHSSPGSIATTHFPESSTTSGRSEE 4825

Query: 1190 SITSHSSIGSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPS 1249
            S  SHSS  ++           S  R + +  F I  G    +  S      TP  SA S
Sbjct: 4826 STASHSSPDTNGITPLPAHFTTSG-RIAESTTFYISPGSMETTLAS---TATTPGLSAKS 4881

Query: 1250 SPKLQHGSTETASPSIKSSTSSSVGTDVTEGPAH-PAPHTRLFHANEEEEPEKKEVSELR 1308
            +       +   + S  S TSSS+  + T   +   + HT  F A+       +E +   
Sbjct: 4882 TILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFH 4941

Query: 1309 SELWEKEMKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTP 1368
            S+    E  L+   +   + A +      T H+       L   +      PG S  ST 
Sbjct: 4942 SKPGSTETTLSPGSITTSSFAQEF----TTPHSQ--PGSALSTVSPASTTVPGLSEEST- 4994

Query: 1369 GQVPGSSALSSPRRSLGLALTHSFGPSLADTDLSP 1403
                  +  SSP  +   A +HS   S+     +P
Sbjct: 4995 ------TFYSSPGSTETTAFSHSNTMSIHSQQSTP 5023



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 299/1403 (21%), Positives = 468/1403 (33%), Gaps = 180/1403 (12%)

Query: 132  APLMSKTLSKSEHSLFQAKG-------SPAGGAKTPL--APLAPNLGKPSRI----PRGP 178
            +P  S T   S HS    +G       SP     T L  +   P L + S      PR P
Sbjct: 2278 SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSP 2337

Query: 179  YAEVKPLSKAPEAAVSEDGKSDDELLSSKAKAQKSSGPVPSAKGQEERAFLKVDPELVVT 238
               + P S        E   S  +  S+ +    +S   P    +E        P    T
Sbjct: 2338 TTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLS-EESTTVYSSSPGSTET 2396

Query: 239  VLGDLEQLLFSQMLDPESQRKRTVQNVLDL------RQNLEETMSSLRGSQV-THSSLEM 291
             +         +  +P +   R       L         L E  ++  GS   T + L  
Sbjct: 2397 TVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA 2456

Query: 292  TCYDSD---------DANPRSVSSLSNRSSPLSWRYGQSSP-RLQAGDAPSVGGSCRSEG 341
            T   +D          ++  + ++LS   S  S   G+S+P RL    +PS   +    G
Sbjct: 2457 TLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRL----SPSSTETTTLPG 2512

Query: 342  TPAWYMHGERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMT 401
            +P      E++   +T P    + LS  +      S +S     + G    +     T T
Sbjct: 2513 SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTT 2572

Query: 402  E--DDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTD 459
                   TT      S  + L  AS   S     +++S +S  ST TA    ST  L   
Sbjct: 2573 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFG 2632

Query: 460  SEKRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKK 519
             E  +   S  S  +     +         S ++   T    R        +S G + + 
Sbjct: 2633 QESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS-PRTTLSPASSTSPGLQGES 2691

Query: 520  PISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPE----GKATDKGKLAVKNTGLQ 575
                 HP S     +PP   T+P+  +          P       +T  G  + K+T + 
Sbjct: 2692 TTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGH-SEKST-IF 2749

Query: 576  RSSSDAGRDRLSDAKKPPSGIARPSTS----GSFGYKKPPPATGTATVMQTGGSATLSKI 631
             SS DA     S A    SG    +TS    GS      P +T T  + +   S T    
Sbjct: 2750 HSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEA--STTFYSS 2807

Query: 632  QKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGA-----------------RSNIQYRSLP 674
             +S    + P +   TSL V   +      PG+                  S   Y S P
Sbjct: 2808 PRSPTTTLSPAS--MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSP 2865

Query: 675  RPA------KSSSMSVTGGRGGP---RPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGR 725
                     +S++ SV G        RP S+        +   GLT      P   AS +
Sbjct: 2866 GSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQ 2925

Query: 726  T-TPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSP------ESTPKNQASHPTATKLA 778
            T  PA +   D  +E     + +  S   +L    S       ESTP   +  P++T+  
Sbjct: 2926 TGLPATLTTADLGEESTTFPSSS-GSTGTTLSPARSTTSGLVGESTPSRLS--PSSTETT 2982

Query: 779  ELPPTP----LRATAKSFVKPPSL--ANLDKVNSNSLDLPSSSDT-------THASKVPD 825
             LP +P    L   + +F   P    A L    + S  +   S T       TH +  PD
Sbjct: 2983 TLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPD 3042

Query: 826  LHATSSASGGPLPSCFTP--SPAPILNINSASFSQGLELMSGFSVP--KETRMYPK---L 878
               TS  S  P  S  +   + A +   ++ + S G +  +  S P   ET + P     
Sbjct: 3043 STTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTIT 3102

Query: 879  SGL-------HRSMESLQM---PMSLPSA-----------FPSSTPV-PTPPAPPAAPTE 916
            SGL       H S  SL     P S  SA           +PSS+   P+PP   AAP E
Sbjct: 3103 SGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVE 3162

Query: 917  EETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQ 976
              T   T+   P +           TL +        S+E T       T+   P +   
Sbjct: 3163 VST---TYHSRPSSTPTTHFSASSTTLGR--------SEEST-------TVHSSPGATGT 3204

Query: 977  SELPSPPALPMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQM-GSTLS 1035
            +  P+  A  + L  +   + I S +  TT     + +    E +   YS  +   +TLS
Sbjct: 3205 ALFPTRSATSV-LVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLS 3263

Query: 1036 LAERPKGMIRSGSFRDPTDDVH--GSVLSLASSASSTYSSAEERMQSEQIRKLRRELESS 1093
                P     SG   + T      GS  + A   S+T     +  +S          +++
Sbjct: 3264 ----PASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQ--ESTASHSSPGSTDTT 3317

Query: 1094 QEKVATLTSQLSANANLV----AAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFL 1149
                +T  S L   +        + E +L+   +    L E +    +       T+   
Sbjct: 3318 LSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPA 3377

Query: 1150 KKKNSEAQA-VIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKK 1208
                 + ++   Q   N+ +TTP            S +S  S +S  +   S  +    +
Sbjct: 3378 GSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR 3437

Query: 1209 KKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSS 1268
             ++S    S   A +    P  +++   +EE  T  SS  S+  +    ++T S   + S
Sbjct: 3438 SEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEES 3497

Query: 1269 TSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEKEMKLTDIRLEALNS 1328
            T+S   T  T      AP T      E         S   +     +   T  R E   +
Sbjct: 3498 TTSHSSTTHT---ISSAPSTTSALVEEPTSYHSSPGSTATTHF--PDSSTTSGRSEESTA 3552

Query: 1329 AHQLDQLRET-MHNMQLEVDLLKAENDRLKVAPG-------PSSGSTPGQVPGS----SA 1376
            +H       T +   +    +L  E+    ++ G       P S +TPG    S    S+
Sbjct: 3553 SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSS 3612

Query: 1377 LSSPRRSLGLALTHSFGPSLADT 1399
              SP  +L  A T S G S   T
Sbjct: 3613 PRSPATTLSPASTTSSGVSEEST 3635



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 202/983 (20%), Positives = 336/983 (34%), Gaps = 168/983 (17%)

Query: 347  MHGERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDD-- 404
            +HGE     H+ P  + + L   +       L  +         S    +  T+T  D  
Sbjct: 1324 VHGEEPTTFHSRPASTHTTL--FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLG 1381

Query: 405  -DITTGWDESSSISSGLSDASDNLS-----------SEEFNASSSLNSLPSTPTASRRNS 452
             + TT    S S  + LS A    S           S     +++L   P+TP+ S +++
Sbjct: 1382 EESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST 1441

Query: 453  TIVLRTDSEKRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSS 512
            T      S   +L+ +  +    SEE         S +   +PG++        +  DS+
Sbjct: 1442 TFYTSPRSPDATLSPATTTSSGVSEE---------SSTSHSQPGST-----HTTAFPDST 1487

Query: 513  KGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNT 572
               +L +  +  H     +G T   A  SP + TA S                 L  ++T
Sbjct: 1488 TTSDLSQEPTTSHS---SQGSTE--ATLSPGSTTASS-----------------LGQQST 1525

Query: 573  GLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQ 632
                S  D     L D     SG+   ST           +TG+     T  S+T + +Q
Sbjct: 1526 TFHSSPGDTETTLLPD-DTITSGLVEAST-------PTHSSTGSLHTTLTPASSTSAGLQ 1577

Query: 633  KSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPR 692
            + S           +S D + S  PG  A     +  Y S P    ++  S +    G  
Sbjct: 1578 EES----TTFQSWPSSSDTTPS-PPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRS 1632

Query: 693  PVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDN 752
              S+++  S  +T    L P+R    T V  G  T +P++    E               
Sbjct: 1633 EESTTVHSSPGATGT-ALFPTR--SATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSE 1689

Query: 753  ISLKSIGSPES-----TPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSN 807
             S     SP S     +P +  S   + +       P      +F    ++  + + ++ 
Sbjct: 1690 KSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTA 1749

Query: 808  SLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFS 867
            S   P S+DTT +       +T+++S GP  + F  SP                      
Sbjct: 1750 SHSSPGSTDTTLSP-----GSTTASSLGPESTTFHSSPG--------------------- 1783

Query: 868  VPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSGS 927
               ET + P  +     +E+        +   SST  P     PA  T  + E  T+   
Sbjct: 1784 -STETTLLPDNTTASGLLEA-------STPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW 1835

Query: 928  PRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPALPM 987
            P +         ++T+P          +  T       T  G P S   +   S  +  +
Sbjct: 1836 PSS---------KDTMPAPPTTTSAFVELST-------TSHGSPSSTPTTHF-SASSTTL 1878

Query: 988  SLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSG 1047
              S +    +      ATTP   RS +    E +   +S      T+   E      RS 
Sbjct: 1879 GRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSE 1938

Query: 1048 SFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSAN 1107
              R      H S     SS  ST S+  E   S                 +T T+    +
Sbjct: 1939 ESRTS----HSSTTHTISSPPSTTSALVEEPTSYH-----------SSPGSTATTHFPDS 1983

Query: 1108 ANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNS----EAQAVIQGA 1163
            +      E+S  + +S+        +   T +L  R T   L  +++     + ++   A
Sbjct: 1984 STTSGRSEESTASHSSQ--------DATGTIVLPARSTTSVLLGESTTSPISSGSMETTA 2035

Query: 1164 LNASETTP--KELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLRSSFNKA 1221
            L  S TTP   E      +S  S ++  S  S +S G S+++     +  S   ++F  +
Sbjct: 2036 LPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDS 2095

Query: 1222 FSI----KKGPKSASSYSDIEEIATPDSSAPSSPKLQH-------GSTETA-SPSIKSST 1269
             +     +    S SS    +    P S+  S P  +        GST+TA SP   S+T
Sbjct: 2096 TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPG--STT 2153

Query: 1270 SSSVGTDVTEGPAHP-APHTRLF 1291
            + S G + T   + P + HT LF
Sbjct: 2154 ALSFGQESTTFHSSPGSTHTTLF 2176



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 224/1096 (20%), Positives = 354/1096 (32%), Gaps = 116/1096 (10%)

Query: 275  TMSSLRGSQVTHSSLEMTCYDSDDANPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVG 334
            T+     S   HSS   T      A  RS +S     S    R   S+  +   ++ +  
Sbjct: 466  TLGHSEESTPVHSSPVATATTPPPA--RSATSGHVEESTAYHRSPGSTQTMHFPESSTTS 523

Query: 335  GSCRSEGTPAWYMHGERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSD 394
            G      T     HG   H   + P  + + L+H S    + S ++      S     S+
Sbjct: 524  GHSEESAT----FHGSTTHTKSSTPSTTAA-LAHTSYHSSLGSTETTHFRDSSTISGRSE 578

Query: 395  LMGKTMTEDDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPST---PTASRRN 451
                + +  D + T    + S  S L    D+  S   + S    +LP +   P  S ++
Sbjct: 579  ESKASHSSPDAMATTVLPAGSTPSVL--VGDSTPSPISSGSMETTALPGSTTKPGLSEKS 636

Query: 452  STIVLRTDSEKRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDS 511
            +T      S   +   + ++    SEE         S      PG++       ES    
Sbjct: 637  TTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASH 696

Query: 512  SKGGELKKPISLG----------------HPGSLKKGKTPPVAVTSPITHTAQSALKVAG 555
            S  G     +S G                 PGS +    P     S +   +        
Sbjct: 697  SSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTR 756

Query: 556  KPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATG 615
             P    +  G    +       S  + +D         S    PST+ S G     P T 
Sbjct: 757  SPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTT-SHGSPSSIPTTH 815

Query: 616  TATVMQTGGSATLSKIQKSSGIPVKPVN----------GRKTSLDVSNSAEPGFLAPGAR 665
             +    T G    S    SS    + ++          G +++   S++      AP   
Sbjct: 816  ISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTT 875

Query: 666  SNI-----QYRSLPRPAKSSSM---SVTGGRGGPRPVSSSIDP----------SLLSTKQ 707
            S +      Y S P    ++     S T GR      S S             S  S   
Sbjct: 876  SALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLL 935

Query: 708  GGLTPSRLK----EPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPES 763
            G  T S +     E T +    TTP    ++       ++ A  L   + +   +    +
Sbjct: 936  GESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEEST 995

Query: 764  TPKNQ--ASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHAS 821
            T +++  ++H TA   +   P   R +  S   P S        S +   PS   TT  S
Sbjct: 996  TSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHS 1055

Query: 822  KVPDLH------ATSSASGGPLPSCFTPSPA-------PILNINSASFSQGLELMSGFSV 868
                        +T++ S G   + F  +P        P    +S        + S    
Sbjct: 1056 SSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 1115

Query: 869  PKETRMYPKLSGLHRSMESLQMPMSLPSAFPSST-PVPTPPAPPAAPTEEETEELTWSGS 927
            P+ T     LS    +   LQ   +     P+ST   P+PP+   AP EE T   T+  S
Sbjct: 1116 PRTT-----LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEEST---TYHRS 1167

Query: 928  P--------RAGQLDSNQRDRNTL----PKKGLRYQLQSQEETKERRHSHTIGGLPESDD 975
            P         A    S   +++T+    P         +   T  R  S T    P S +
Sbjct: 1168 PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE 1227

Query: 976  QSELPSPPALP-MSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMGSTL 1034
             + LP     P +S ++    ++  SPT   +P    S  +          S SQ GST 
Sbjct: 1228 ITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTT----SRSQPGSTH 1283

Query: 1035 SLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTY-SSAEERMQSEQIRKLRRELESS 1093
            S    P      G   + T  V+ S  S  S+ ++ +  S    +  E+         S+
Sbjct: 1284 STVS-PASTTTPGLSEEST-TVYSS--SRGSTETTVFPHSTTTSVHGEEPTTFHSRPAST 1339

Query: 1094 QEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETA---EEKDTELLDLRETIDFLK 1150
               + T  S  S       AF  S  +  + L     TA   EE  T       T   L 
Sbjct: 1340 HTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLS 1399

Query: 1151 KKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKK 1210
               S    ++ G    S  +P          S +  SL S  S +   S +  DA     
Sbjct: 1400 PARSTTSGLV-GESTPSRLSPSSTETTTLPGSPTTPSL-SEKSTTFYTSPRSPDATLSPA 1457

Query: 1211 KSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPD-SSAPSSPKLQHGSTE-TASPSIKSS 1268
             +       ++ +    P S  + +  +   T D S  P++     GSTE T SP   S+
Sbjct: 1458 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPG--ST 1515

Query: 1269 TSSSVGTDVTEGPAHP 1284
            T+SS+G   T   + P
Sbjct: 1516 TASSLGQQSTTFHSSP 1531



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 233/1153 (20%), Positives = 376/1153 (32%), Gaps = 148/1153 (12%)

Query: 350  ERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTE--DDDIT 407
            E++   H+ P    + LS  S      S +S     + G    +     T T       T
Sbjct: 2047 EKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHST 2106

Query: 408  TGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAE 467
            T      S  + L  AS   S     +++S +S  ST TA    ST  L    E  +   
Sbjct: 2107 TSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHS 2166

Query: 468  SGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPG 527
            S  S  +     +         S ++   T    R        +S G + +      HP 
Sbjct: 2167 SPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS-PRTTLSPASSTSPGLQGESTAFQTHPA 2225

Query: 528  SLKKGKTPPVAVTSPITHTAQSALKVAGKPE----GKATDKGKLAVKNTGLQRSSSDAGR 583
            S     +PP   T+P+  +          P       +T  G  + K+T +  SS DA  
Sbjct: 2226 STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGH-SEKST-IFHSSPDASG 2283

Query: 584  DRLSDAKKPPSGIARPSTS----GSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPV 639
               S A    SG    +TS    GS      P +T T  + +   S T     +S    +
Sbjct: 2284 TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEA--STTFYSSPRSPTTTL 2341

Query: 640  KPVNGRKTSLDVSNSAEPGFLAPGA-RSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSI 698
             P +   TSL V   +      PG+  S +   S   P  S   S T     P    +++
Sbjct: 2342 SPAS--MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE-STTVYSSSPGSTETTV 2398

Query: 699  DPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSI 758
             P   +T   G  P+     ++ AS  TT    + T               +  ++ +S 
Sbjct: 2399 FPRTPTTSVRGEEPTTFH--SRPASTHTTLFTEDST---------------TSGLTEEST 2441

Query: 759  GSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTT 818
              P S    Q   P     A+L                           S   PSSS +T
Sbjct: 2442 AFPGSPASTQTGLPATLTTADL------------------------GEESTTFPSSSGST 2477

Query: 819  HASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSG--FSVPK--ETRM 874
              +  P    TS   G   PS  +PS      +  +  +  L   S   ++ P+  +  +
Sbjct: 2478 GTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL 2537

Query: 875  YPKLSGLHRSMESLQMPMSLP-----SAFPSSTPVP-----------------TPPAPPA 912
             P  +      E      S P     +AFP ST  P                 T   P +
Sbjct: 2538 SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS 2597

Query: 913  APTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPE 972
              T   ++E T S S   G  D+     +T     L +  +S         +HT    P+
Sbjct: 2598 TTTSGPSQESTTSHS-SPGSTDTALSPGST---TALSFGQESTTFHSSPGSTHTT-LFPD 2652

Query: 973  SDDQSELPSPPALPMSLSAKGQLTNIVSPTAATTPRIT-RSNSIPTHEAAFELYSGSQMG 1031
            S   S +    A     S+ G     +SP ++T+P +   S +  TH A+          
Sbjct: 2653 STTSSGIVE--ASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPST 2710

Query: 1032 STLSLAER---------------PKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEE 1076
            +T  + E                P     SG     T   H S  +  ++ SS +S+   
Sbjct: 2711 ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKST-IFHSSPDASGTTPSSAHSTTSG 2769

Query: 1077 RMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETA---- 1132
            R +S   R      E +    +T T  LS  +     F  S  + T+ L   + T+    
Sbjct: 2770 RGESTTSRISPGSTEITTLPGSTTTPGLSEAS---TTFYSSPRSPTTTLSPASMTSLGVG 2826

Query: 1133 EEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTP--KELRIKRQNSSDSISSLNS 1190
            EE  T       T   +   ++    + + +     ++P   E  +  ++++ S+     
Sbjct: 2827 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEP 2886

Query: 1191 ITSHSSIGSSKDADAKKKKKKSWLRSSFNKAF-----SIKKGPKSASSYSDIEEIATPDS 1245
             T HS   S+      +    S L    + AF     S + G  +  + +D+ E +T   
Sbjct: 2887 TTFHSRPASTHTTLFTEDSTTSGLTEE-STAFPGSPASTQTGLPATLTTADLGEEST--- 2942

Query: 1246 SAPSSPKLQHGSTETASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVS 1305
            + PSS     GST T     +S+TS  VG       +  +  T     +    P    +S
Sbjct: 2943 TFPSS----SGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS----PTTPSLS 2994

Query: 1306 ELRSELWEKEMKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSG 1365
            E  +  +            A  ++  + +   T H+        +  +      P  ++ 
Sbjct: 2995 EKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHS--------QPGSTHTTAFPDSTTT 3046

Query: 1366 STPGQVP----GSSALSSPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVTLRVV 1421
            S   Q P     S   +    S G     S G        SP D  +T  P + +T  +V
Sbjct: 3047 SGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLV 3106

Query: 1422 VRMPPQHIIKGDL 1434
                P H   G L
Sbjct: 3107 EASTPTHSSTGSL 3119



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 219/1108 (19%), Positives = 363/1108 (32%), Gaps = 185/1108 (16%)

Query: 282  SQVTHSSLEMTCYDSDDANPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEG 341
            S+++ SS E T        P    SLS +S+  ++     SP      A +       E 
Sbjct: 2972 SRLSPSSTETTTLPGSPTTP----SLSEKST--TFYTSPRSPDATLSPATTTSSGVSEES 3025

Query: 342  TPAWYMHGERAHYSHTMPMRSPSKLSHISRLELVE--SLDSDEVDLKSGYMSDSDLMGKT 399
            + +    G     +HT      +  S +S+       S  S E  L  G  + S L  ++
Sbjct: 3026 STSHSQPGS----THTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQS 3081

Query: 400  MT---EDDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVL 456
             T      D  T      +I+SGL +AS    S   +  ++L    ST    +  ST   
Sbjct: 3082 TTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQ 3141

Query: 457  RTDSEKRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGE 516
                          SW S S+           G+       S     RP S   +     
Sbjct: 3142 --------------SWPSSSDTTPSPP-----GTTAAPVEVSTTYHSRPSSTPTTHFSAS 3182

Query: 517  LKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQR 576
                 +LG         + P A  + +  T  +   + G+P       G  + + T L  
Sbjct: 3183 ---STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSG--STETTALPG 3237

Query: 577  SSSDAGRDRLS----DAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQ 632
            S++ AG    S     + + P     P+++ S G  +      + T     GS   +   
Sbjct: 3238 STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEE-----STTSHSRPGSTHTTAFP 3292

Query: 633  KSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPR 692
             S+ +P   V+   T+   S  +    L+PG+ +          A S     T    GP 
Sbjct: 3293 GSTTMP--GVSQESTASHSSPGSTDTTLSPGSTT----------ASSLGPESTTFHSGPG 3340

Query: 693  PVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDN 752
               +++ P   +T   GL  +     +   S  TT +P   T R+ E    ++     D 
Sbjct: 3341 STETTLLPD--NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDT 3398

Query: 753  -------------ISLKSIGSPESTPKNQASHPTAT--------------KLAELPPTPL 785
                         +S  S GSP STP    S  + T                    P+P 
Sbjct: 3399 TPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPA 3458

Query: 786  RATAKSFVKPPSLANLDKVNSNSLDLPSS---------SDTTHASKVPDLHATSSASGGP 836
            R+T    V+  +  +    ++ ++  P S         S T+H+S    + +  S +   
Sbjct: 3459 RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSAL 3518

Query: 837  L--PSCFTPSPAPILNI------------------NSASFSQGLELMSGFSVPK----ET 872
            +  P+ +  SP                        +S+  + G  ++   S       E+
Sbjct: 3519 VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 3578

Query: 873  RMYPKLSGLHRSMESLQMPMSL--------PSAFPSSTPVPTPPAPPAAPTEEETEELTW 924
               P  SG   SME+  +P S          + F SS   P     PA+ T     E + 
Sbjct: 3579 TTSPISSG---SMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEEST 3635

Query: 925  SGSPRAGQLDSNQ-RDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELP-SP 982
            +   R G   +    D  T P  GL             RHS T    P S D + LP S 
Sbjct: 3636 TSHSRPGSTHTTAFPDSTTTP--GL------------SRHSTTSHSSPGSTDTTLLPAST 3681

Query: 983  PALPMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMGSTLSLAERPKG 1042
                 S  +    ++  S   A +P  T + S       F    GS   +    +    G
Sbjct: 3682 TTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSG 3741

Query: 1043 MIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTS 1102
            ++ + +    +     + LS ASS S                 L+ E  + Q   A+  +
Sbjct: 3742 IVEASTRVHSSTGSPRTTLSPASSTSP---------------GLQGESTAFQTHPASTHT 3786

Query: 1103 QLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQG 1162
              S  +   A  E+S    T+  R    T     T       T       +SE   +   
Sbjct: 3787 TPSPPSTATAPVEES----TTYHRSPGST----PTTHFPASST----TSGHSEKSTIFHS 3834

Query: 1163 ALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLRSSFNKAF 1222
            + +AS TTP          S +     S TS  S GS++            L  +    +
Sbjct: 3835 SPDASGTTPSSAH------STTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFY 3888

Query: 1223 SIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGST-ETASPSIKSSTSSSVGTDVTEGP 1281
            S  + P +  S + +  +   + S  S  + Q GST  T SP+  ++   S  +      
Sbjct: 3889 SSPRSPTTTLSPASMTSLGVGEESTTS--RSQPGSTHSTVSPASTTTPGLSEESTTVYSS 3946

Query: 1282 AHPAPHTRLFHANEEEEPEKKEVSELRS 1309
            +  +  T +F  +      ++E +   S
Sbjct: 3947 SPGSTETTVFPRSTTTSVRREEPTTFHS 3974



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 131/610 (21%), Positives = 205/610 (33%), Gaps = 80/610 (13%)

Query: 302  RSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPMR 361
            RS  S +  SSP++     S  R           +  S       MH   ++   T    
Sbjct: 4520 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNT--TSGRG 4577

Query: 362  SPSKLSHISRLELVESLDSDE---VDLKSGYMSDSDLMGKTMTEDDDITTGWDESSSISS 418
              S  SH S    + S  S     V+  + Y S       T   D   T+G  E S+ S 
Sbjct: 4578 EESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH 4637

Query: 419  GLSDAS----------------DNLSSEEFNASSSLNSLP---STPTASRRNSTIVLRTD 459
               DA+                ++ +S   + S    +LP   +TP  S +++T      
Sbjct: 4638 SSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPS 4697

Query: 460  SEKRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKK 519
            S   +   +  +    SEE         + +    P  S       ES    S  G  + 
Sbjct: 4698 STPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQT 4757

Query: 520  ---PISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQR 576
               P S    G  ++ +T   + T  I+    +   +  +P    +  G +A   T    
Sbjct: 4758 MHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIAT--THFPE 4815

Query: 577  SSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSG 636
            SS+ +GR   S A       + P T+G      P PA  T          T  +I +S+ 
Sbjct: 4816 SSTTSGRSEESTASH-----SSPDTNGI----TPLPAHFT----------TSGRIAESTT 4856

Query: 637  IPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKS---SSMSVTGGRGGPRP 693
              + P  G   +   S +  PG     A+S I Y S   P ++   +SM+ +   G P  
Sbjct: 4857 FYISP--GSMETTLASTATTPGL---SAKSTILYSSSRSPDQTLSPASMTSSSISGEPTS 4911

Query: 694  VSSSIDPSLL-----STKQGGLTPSRLKEPTKVASGRTTPAPVN----------QTDREK 738
            + S  + +       ST   GL+       +K  S  TT +P +           T   +
Sbjct: 4912 LYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQ 4971

Query: 739  EKAKAKAVALDSDNI------SLKSIGSPESTPKNQASHPTATKLAELPPTPLRATA--K 790
              +    V+  S  +      S     SP ST     SH     +     TP   +    
Sbjct: 4972 PGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFT 5031

Query: 791  SFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILN 850
              V P +L   D +   S    SSSD T  + +P     S   G P     +PSP     
Sbjct: 5032 HTVLPATLTTTD-IGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTL 5090

Query: 851  INSASFSQGL 860
              ++S + GL
Sbjct: 5091 FPASSSTSGL 5100



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 210/1003 (20%), Positives = 329/1003 (32%), Gaps = 135/1003 (13%)

Query: 350  ERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTE--DDDIT 407
            E++   H+ P    + LS  S      S +S     + G    +     T T       T
Sbjct: 3604 EKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHST 3663

Query: 408  TGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAE 467
            T      S  + L  AS   S     +++S +S  ST TA    ST  L    E  +   
Sbjct: 3664 TSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHS 3723

Query: 468  SGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPG 527
            S  S  +     +         S ++   T    R        +S G + +      HP 
Sbjct: 3724 SPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS-PRTTLSPASSTSPGLQGESTAFQTHPA 3782

Query: 528  SLKKGKTPPVAVTSPITHTAQSALKVAGKPE----GKATDKGKLAVKNTGLQRSSSDAGR 583
            S     +PP   T+P+  +          P       +T  G  + K+T +  SS DA  
Sbjct: 3783 STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGH-SEKST-IFHSSPDASG 3840

Query: 584  DRLSDAKKPPSGIARPSTS----GSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPV 639
               S A    SG    +TS    GS      P +T T  + +   S T     +S    +
Sbjct: 3841 TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEA--STTFYSSPRSPTTTL 3898

Query: 640  KPVNGRKTSLDVSNSAEPGFLAPGA-RSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSI 698
             P +   TSL V   +      PG+  S +   S   P  S   S T     P    +++
Sbjct: 3899 SPAS--MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE-STTVYSSSPGSTETTV 3955

Query: 699  DPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSI 758
             P   +T        R +EPT   S    PA  + T   ++          +  ++ +S 
Sbjct: 3956 FPRSTTTSV------RREEPTTFHS---RPASTHTTLFTEDST--------TSGLTEEST 3998

Query: 759  GSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTT 818
              P S    Q   P     A+L                           S   PSSS +T
Sbjct: 3999 AFPGSPASTQTGLPATLTTADL------------------------GEESTTFPSSSGST 4034

Query: 819  HASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSG--FSVPK--ETRM 874
                 P    TS   G   PS  +PS      +  +  +  L   S   ++ P+  +  +
Sbjct: 4035 GTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL 4094

Query: 875  YPKLSGLHRSMESLQMPMSLP-----SAFPSSTPVPTPPAPPAA--PTEEETEELTWSGS 927
             P  +      E      S P     +AFP ST        P     ++  TE     GS
Sbjct: 4095 SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGS 4154

Query: 928  PRAGQL-------DSNQRDRNT--LPKKGLRYQL--------------------QSQEET 958
              A  L        S+  D  T  LP   +   L                     S   T
Sbjct: 4155 TTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTST 4214

Query: 959  KERRHSHTIGGLPESDDQSELPSPP---ALPMSLSAKGQLTNIVSPT---AATTPRITRS 1012
              +  S T    P S D +  PSPP   A+P+ +S         +PT   +A++  + RS
Sbjct: 4215 GLQEESTTFQSWPSSSDTT--PSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRS 4272

Query: 1013 NSIPTHE----AAFELYSGSQMGSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSAS 1068
                T      A       ++  +++ + E     I SGS    T  + GS  +   S  
Sbjct: 4273 EESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGS--TETTALPGSTTTAGLSEK 4330

Query: 1069 STYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHL 1128
            ST   +  R     +           E+  T  S+  +          ++  ++      
Sbjct: 4331 STTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTAS 4390

Query: 1129 AETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSL 1188
              +    DT L     T   L  +++        +  ++ETT     +   N++ S    
Sbjct: 4391 HSSPGSTDTTLSPGSTTASSLGPEST----TFHSSPGSTETT-----LLPDNTTASGLLE 4441

Query: 1189 NSITSHSSIGS-----SKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATP 1243
             S   HSS GS     S      ++ + +  +S  N   +    P + S++    E++T 
Sbjct: 4442 ASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAF---VELSTT 4498

Query: 1244 DSSAPSSPKLQH--GSTETASPSIKSST--SSSVGTDVTEGPA 1282
               +PSS    H   S+ T   S +S+T  SS V T  T  PA
Sbjct: 4499 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPA 4541


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 105/439 (23%), Positives = 159/439 (36%), Gaps = 63/439 (14%)

Query: 495 PGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKK-GKTPPVAVTSPITHTAQSALKV 553
           P     R  RP +    S  GE   P     PG +   G+        P+    Q  L++
Sbjct: 75  PRAGPTRTSRPPA----SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL---GQKGLRI 127

Query: 554 AGKP---EGKATDKGKLAVKNTGLQRSSS-------DAGRDRLSDAKKPPSGIARPSTSG 603
           + +     GKAT+  K +  + G +R +S            R S A     G+ RP+ S 
Sbjct: 128 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 187

Query: 604 SFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPG 663
                +P P T        G   ++S   + S     P   R+ S      A  G   P 
Sbjct: 188 -----RPRPPT-------EGPRKSVSSASEHSTTEPSPAARRRPS------AGGGLQRPA 229

Query: 664 ARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVAS 723
           +RS     S   P  S + S    RG PR  +    P     +   L P ++  P K A+
Sbjct: 230 SRS---LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ--ALRPPQVTPPRKDAA 284

Query: 724 GRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAE---- 779
               P   +        A     A  S    L+++ SP +TP +QA+    +   +    
Sbjct: 285 PALGPLSSSPLATPSPSAPPSPSAPPS----LQTLPSPPATPPSQATTSLGSPTLQATHS 340

Query: 780 -LPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLP 838
            LP  PL   A    + P    L  + +     P +S        P   A ++ +   L 
Sbjct: 341 FLPSPPLSPLATPPPQAPPALALPPLQAPPS--PPASPPLSPLATPSPQAPNALAVHLLQ 398

Query: 839 SCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSA- 897
           + F+P P+P +    A FS         S    ++  P L+        LQ+P S P++ 
Sbjct: 399 APFSPPPSPPVQ---APFSPPASPPVSPSATPPSQAPPSLAA-----PPLQVPPSPPASP 450

Query: 898 --FPSSTPVPTPPAPPAAP 914
              PS+TP P  P P AAP
Sbjct: 451 PMSPSATPPPQAPPPLAAP 469



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 101/440 (22%), Positives = 150/440 (34%), Gaps = 55/440 (12%)

Query: 510 DSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAV 569
           D +K G   +  +   PG L            P+T  A   L  AG    K   +    +
Sbjct: 6   DKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI 65

Query: 570 KNTGLQRSSSDAGRDRLSDAKKPPSGI---ARPSTSGSFG-YKKPPPATGTATVMQTGGS 625
               +  S+  AG  R S  + P SG    A P+ + S G    P  A+GT      G  
Sbjct: 66  GGATIPESAPRAGPTRTS--RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123

Query: 626 ATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYR---------SLPRP 676
                 +++          ++++L      +     PG  S    R          LPRP
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183

Query: 677 AKSSSMSVTGGRGGPRPVSSSI------DPSLLSTKQGGLTPSRLKEPTKVASGRTTP-- 728
           A S+         GPR   SS       +PS  + ++        +  ++  S   TP  
Sbjct: 184 APSARPRPP--TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 241

Query: 729 APVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELP-PTPLRA 787
           +P       +   +A A         L+++  P+ TP  + + P    L+  P  TP  +
Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301

Query: 788 TAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSS-ASGGPLPSCFTPSPA 846
              S   PPSL  L    +     PS + T+  S  P L AT S     PL    TP P 
Sbjct: 302 APPSPSAPPSLQTLPSPPATP---PSQATTSLGS--PTLQATHSFLPSPPLSPLATPPPQ 356

Query: 847 --PILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHR---------SMESLQMPMSLP 895
             P L             +     P      P LS L           ++  LQ P S P
Sbjct: 357 APPAL------------ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404

Query: 896 SAFPSSTPVPTPPAPPAAPT 915
            + P   P   P +PP +P+
Sbjct: 405 PSPPVQAPFSPPASPPVSPS 424



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 83/361 (22%), Positives = 129/361 (35%), Gaps = 66/361 (18%)

Query: 575 QRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKS 634
           +R  + AG    + A + P G+  P   GS    +PPP    A +   G +  + +    
Sbjct: 4   KRDKAKAGAAARTPAARAP-GLLTPRPPGS---PRPPPPVTPAALRVLGAAGAVGR---- 55

Query: 635 SGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPV 694
                KP+  R   +  +   E    A   R++       RP  S       GRG   P 
Sbjct: 56  -----KPLAERAGGIGGATIPESAPRAGPTRTS-------RPPAS-------GRGERAPP 96

Query: 695 SSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDRE--KEKAKAKAVALDSDN 752
           + +  P  +S+      P R       ASG T P P+ Q       E+  A+  A ++  
Sbjct: 97  AKNTSPGPVSS------PGR-------ASGTTRPGPLGQKGLRISAEETVARGKATEAPK 143

Query: 753 ISLKSIGSPEST--PKNQASHPTATKLAELPPTPL---RATAKSFVKPPSLANLDKVNSN 807
            S  S G+   T  P      P   + +    T +   R    +  +PP+      V+S 
Sbjct: 144 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS- 202

Query: 808 SLDLPSSSDTTHASKVPDLHATSSASGG-------PLPSCFTPSPAPILNINSASFSQGL 860
                S   TT  S  P      SA GG        L S  TP  +P  +  SA  +   
Sbjct: 203 ----ASEHSTTEPS--PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 256

Query: 861 ELMSGFSVPKETRMY--PKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEE 918
                   PK  +    P+++   +       P+S   + P +TP P+ P  P+AP   +
Sbjct: 257 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS---SSPLATPSPSAPPSPSAPPSLQ 313

Query: 919 T 919
           T
Sbjct: 314 T 314



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 98/420 (23%), Positives = 138/420 (32%), Gaps = 72/420 (17%)

Query: 536 PVAVTSPITHTAQSA---LKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKP 592
           P+A  SP    + SA   L+    P      +   ++ +  LQ + S      LS    P
Sbjct: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 353

Query: 593 PS----GIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKS--SGIPVKPVNGR- 645
           P      +A P           PP +  AT      +A    + ++  S  P  PV    
Sbjct: 354 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 413

Query: 646 --KTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMS--VTGGRGGPRPVSSSIDPS 701
               S  VS SA P   AP + +    +  P P  S  MS   T     P P+++   P 
Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA---PP 470

Query: 702 LLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSP 761
           L   K     P  L  P   A     P+P          A     A  S + SL    SP
Sbjct: 471 LQLAKPPPQAPPALATPPLQA----LPSP---------PASFPGQAPFSPSASLPM--SP 515

Query: 762 ESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHAS 821
            +TP  QA    A  L ++PP+P                           P+S       
Sbjct: 516 LATPPPQAPPVLAAPLLQVPPSP---------------------------PASPTLQAPR 548

Query: 822 KVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLEL----MSGFSVPKETRMY-- 875
           + P     +S SG  L     P P P  + + +S   G +L     S  S P+E R Y  
Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 608

Query: 876 -PKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLD 934
            P+           ++    P+A+         PAPP A        L W  +   G  D
Sbjct: 609 GPEGGAAASPPPDAELAACHPAAWSRG------PAPPLAFRGAPGAPLPWPPATGPGSAD 662


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 99/388 (25%), Positives = 140/388 (36%), Gaps = 92/388 (23%)

Query: 588 DAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATL-SKIQKSSGIPVKPVNGRK 646
           DAK  P G   PS+S   G +   P        Q      +  K+Q+ +  P     GR 
Sbjct: 248 DAKDVPGG--GPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPA----GRP 301

Query: 647 TSLD--VSNSAEPGFLAPGARSNIQYRSLPRPAKSSSM--------SVTGGRGGPRPVSS 696
           T      S S  P    P  RS++Q  +L   A SSS+         V   RG P+P   
Sbjct: 302 TPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPSEG 361

Query: 697 SI----DPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDN 752
           +     DP  ++  Q    P +   P   +S   +P P +Q  R+ E    + VA  S  
Sbjct: 362 TPAPRKDPPWITLVQA--EPKKKPAPLPPSS---SPGPPSQDSRQVENGGTEEVAQPSPT 416

Query: 753 ISLKS----------------------------IGSPESTPKN----QASHPTATKLAEL 780
            SL+S                            +G PESTPK+        PT++   + 
Sbjct: 417 ASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKK 476

Query: 781 PPTP---------LRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSS 831
            P P         L A+  S  +PPS      ++  SL   S+S T  A  +       S
Sbjct: 477 RPAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKS 536

Query: 832 ASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMP 891
           +S   + +  TP     L+ NS+  S G EL+            P++          QMP
Sbjct: 537 SSEPAVHAPGTPGNPVSLSTNSSLASSG-ELVE-----------PRVE---------QMP 575

Query: 892 MSLPSAFP----SSTPVPTPPAPPAAPT 915
            + P   P    SS P P  P   A PT
Sbjct: 576 QASPGLAPRTRGSSGPQPAKPCSGATPT 603



 Score = 38.1 bits (87), Expect = 0.081
 Identities = 77/376 (20%), Positives = 124/376 (32%), Gaps = 47/376 (12%)

Query: 660  LAPGARSNIQYRSLPRPAKSSSMSVT--------GGRGGPRPVSSSIDPSLLSTKQGGLT 711
            L PG RS  +     +P +     +         GG     P  +  D    S +     
Sbjct: 221  LGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQI 280

Query: 712  PSRLKEPTKVA------SGRTTPAP--VNQTDREKEKAKAKAVALDSDNISLKSIGSPES 763
            P++ + P K+       +GR TPAP   +++            +L  +N+ ++  GS  S
Sbjct: 281  PTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENL-VEQAGS--S 337

Query: 764  TPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLD-KVNSNSLDLPSSSDTTHASK 822
            +  N   H          P P   T      PP +  +  +       LP SS     S 
Sbjct: 338  SLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSS-----SP 392

Query: 823  VPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRM--YPKLSG 880
             P    +     G       PSP   L     +  +  E       P    +   P L  
Sbjct: 393  GPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGH 452

Query: 881  LHRSMESLQMPMSL-PSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRD 939
               + +SL     + P++ P +   P P AP A+P       L+ S  P A         
Sbjct: 453  PESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSA--------- 503

Query: 940  RNTLPKKGLRYQLQSQEETKERRHSHTI--GGLPESDDQSEL--PSPPALPMSLSAKGQL 995
                P   L  +  S E   +   +  +    +P+S  +  +  P  P  P+SLS    L
Sbjct: 504  ---TPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSL 560

Query: 996  TN---IVSPTAATTPR 1008
             +   +V P     P+
Sbjct: 561  ASSGELVEPRVEQMPQ 576



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 61/282 (21%), Positives = 101/282 (35%), Gaps = 30/282 (10%)

Query: 830  SSASGGPLPS------CFTPSPAPILNINSASFSQGLELMSGFSVPKETRMY----PKLS 879
            S  +G P P+        TP+P P     S+   + L   +G S     R++    PK  
Sbjct: 295  SPPAGRPTPAPRKASESTTPAP-PTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPR 353

Query: 880  GLHRSMESLQMP------MSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQL 933
            G  +  E    P      ++L  A P   P P PP+    P  +++ ++   G+    Q 
Sbjct: 354  GTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQ- 412

Query: 934  DSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIG---GLPESDDQSELP----SPPALP 986
             S      + P      + + +EE      S       G PES  +S  P    +P + P
Sbjct: 413  PSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSP 472

Query: 987  MSLSAKGQLTNIVSPTAATTPRITRS---NSIPTHEAAFELYSGSQMGST--LSLAERPK 1041
             +           SP A    R++ S   ++ P+   + E  S      T    L E P 
Sbjct: 473  KTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPA 532

Query: 1042 GMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQI 1083
                S           G+ +SL++++S   S      + EQ+
Sbjct: 533  VPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQM 574


>gi|42476164 POU class 2 homeobox 1 [Homo sapiens]
          Length = 743

 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 101/475 (21%), Positives = 179/475 (37%), Gaps = 63/475 (13%)

Query: 382 EVDLKSGYMSDSDLMGKTMTEDDDITTGWDESSSIS----SGLSDASDNLSSEEFNASSS 437
           +V L  G +  +D    T++  + +   +     +       L+DA +  S    ++ S+
Sbjct: 308 DVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAENLSSDSSLSSPSA 367

Query: 438 LNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPGT 497
           LNS P     SRR         + + +L +S    F E+++   +++   +  L ME   
Sbjct: 368 LNS-PGIEGLSRRRKKRTSIETNIRVALEKS----FLENQKPTSEEITMIADQLNMEKEV 422

Query: 498 SK-W---RRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKV 553
            + W   RR++ +  +  S GG    PI    P       T P  VTS    +A + L V
Sbjct: 423 IRVWFCNRRQKEKRINPPSSGGTSSSPIKAIFPSPTSLVATTPSLVTS----SAATTLTV 478

Query: 554 AGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPA 613
           +  P    T      +  TG   ++S+     +S A    S +  PS S        P  
Sbjct: 479 S--PVLPLTSAAVTNLSVTGTSDTTSNNTATVISTAPPASSAVTSPSLS--------PSP 528

Query: 614 TGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSL 673
           + +A+  +   ++  S  Q +S     P+   +  +  S     G     A +      L
Sbjct: 529 SASASTSEASSASETSTTQTTSTPLSSPLGTSQVMVTAS-----GLQTAAAAALQGAAQL 583

Query: 674 PRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQ 733
           P  A  ++M+   G          ++PSL++  Q     + L       SG  +PA ++ 
Sbjct: 584 PANASLAAMAAAAG----------LNPSLMAPSQFAAGGALLSLNPGTLSGALSPALMS- 632

Query: 734 TDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFV 793
                          +S   +++++ S  S P            A     P   TA  F+
Sbjct: 633 ---------------NSTLATIQALASGGSLPITSLDATGNLVFANAGGAPNIVTAPLFL 677

Query: 794 KPPSLANLDKVNSNSLDLPSSSDTTHASKVP--DLHATSSASGGPLPSCFTPSPA 846
            P    NL  + SN + L S++  +  +  P   LHATS+++     S FT + A
Sbjct: 678 NP---QNLSLLTSNPVSLVSAAAASAGNSAPVASLHATSTSAESIQNSLFTVASA 729



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 39/183 (21%), Positives = 78/183 (42%), Gaps = 14/183 (7%)

Query: 939  DRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPAL----PMSLSAKGQ 994
            D+  + K+ +R    ++ + ++R +  + GG   S  ++  PSP +L    P  +++   
Sbjct: 414  DQLNMEKEVIRVWFCNRRQKEKRINPPSSGGTSSSPIKAIFPSPTSLVATTPSLVTSSAA 473

Query: 995  LTNIVSPT-AATTPRITRSNSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSGSFR-DP 1052
             T  VSP    T+  +T  +   T +      + +   + +S A      + S S    P
Sbjct: 474  TTLTVSPVLPLTSAAVTNLSVTGTSDT-----TSNNTATVISTAPPASSAVTSPSLSPSP 528

Query: 1053 TDDVHGSVLSLASSASSTYSSA---EERMQSEQIRKLRRELESSQEKVATLTSQLSANAN 1109
            +     S  S AS  S+T +++      + + Q+      L+++        +QL ANA+
Sbjct: 529  SASASTSEASSASETSTTQTTSTPLSSPLGTSQVMVTASGLQTAAAAALQGAAQLPANAS 588

Query: 1110 LVA 1112
            L A
Sbjct: 589  LAA 591


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 163/760 (21%), Positives = 272/760 (35%), Gaps = 116/760 (15%)

Query: 579  SDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATL--SKIQKSSG 636
            S   RD  +D+  P S    P TS  F    P  AT T +   T  SAT+  SK    + 
Sbjct: 949  SQTNRDTFNDSAAPQS-TTWPETSPRFKTGLPS-ATTTVSTSATSLSATVMVSKFTSPAT 1006

Query: 637  IPVKPVNGRKTS---LDVSNSAEPGFLAPGARS-----------NIQYRSLPRPAKSSSM 682
              ++  + R+ S   L    +  PG +A  + +            +    LP    +SS 
Sbjct: 1007 SSMEATSIREPSTTILTTETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSE 1066

Query: 683  SVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAK 742
            +          VS S+ PS      G  TP R                   T +  +   
Sbjct: 1067 TSMDFTMAKESVSMSVSPSQSMDAAGSSTPGR-------------------TSQFVDTFS 1107

Query: 743  AKAVALDSDNISLKSIGSPES-TPKNQASHPTA--------TKLAELPPTPLRATAK--- 790
                 L S  I++   G+  + TP+  A+HP +        T L  L  +P   T K   
Sbjct: 1108 DDVYHLTSREITIPRDGTSSALTPQMTATHPPSPDPGSARSTWLGILSSSPSSPTPKVTM 1167

Query: 791  ----SFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASG-GPLPSCFTPSP 845
                S  +  +   +D V ++  ++P+   TT  S  P    TS A G   L    TPSP
Sbjct: 1168 SSTFSTQRVTTSMIMDTVETSRWNMPNLPSTT--SLTPSNIPTSGAIGKSTLVPLDTPSP 1225

Query: 846  APILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMES---LQMPMS--------L 894
            A  L  +      GL  +S +  P+ T       G H S ES   +++ M+         
Sbjct: 1226 ATSLEASEG----GLPTLSTY--PESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYT 1279

Query: 895  PSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQL-DSNQRDRNTLPKKGLRYQLQ 953
            P  FPS            A +   + E+T  G    G   D       T PK     Q+ 
Sbjct: 1280 PLTFPSIETHIHVSTARMAYSSGSSPEMTAPGETNTGSTWDPTTYITTTDPKDTSSAQVS 1339

Query: 954  SQEETKERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSP-TAATTPRITRS 1012
            +    +  R +       E+  ++E  +P A   S        N+ SP T A T   T  
Sbjct: 1340 TPHSVRTLRTT-------ENHPKTESATPAAYSGSPKISSS-PNLTSPATKAWTITDTTE 1391

Query: 1013 NSIPTH-------EAAFELYSGSQMGSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLAS 1065
            +S   H        + FE  S     S +     P       S  + T DV G  L LA 
Sbjct: 1392 HSTQLHYTKLAEKSSGFETQSAPGPVSVVI----PTSPTIGSSTLELTSDVPGEPLVLAP 1447

Query: 1066 SASSTYSSAEERMQS----EQIRKLRRELESSQEKVATLT------------SQLSANAN 1109
            S  +T +       S    E++     ++ S    ++T              S+  A+ +
Sbjct: 1448 SEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELSKSEADTS 1507

Query: 1110 LVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASET 1169
             +   + + ++    +R L  T +     +  L  T   + + +++AQ  +   ++ +  
Sbjct: 1508 AIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLSATMSPTHV 1567

Query: 1170 TPKELRIKRQNSSDSISSLNSITS-HSSIGSSKDADAKKKKKKSWLRSSFNKAFSIKKGP 1228
            T     +K Q S  + +S + +T  +  +G+     +  +    W  S+   +  I+ GP
Sbjct: 1568 TQS---LKDQTSIPASASPSHLTEVYPELGTQ--GRSSSEATTFWKPSTDTLSREIETGP 1622

Query: 1229 KSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSS 1268
             +  S   ++   T  SS+  +  + H    T+SP+  S+
Sbjct: 1623 TNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETST 1662



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 224/1142 (19%), Positives = 404/1142 (35%), Gaps = 165/1142 (14%)

Query: 411  DESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRR----NSTIVLRTDSEKRSLA 466
            +E+SS+SS LS  +   +S       S++S P   TA        +T +LRT SE  + +
Sbjct: 8556 EEASSVSSSLSSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTSSEPETSS 8615

Query: 467  ESGLSWFS------ESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKP 520
               LS  S          K  +K+   S +  +  GT  ++   P S        +   P
Sbjct: 8616 PPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTSP 8675

Query: 521  I----SLGHPG-SLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQ 575
            +    +LG+   S      P   +T P +       +++   E  +  +   ++      
Sbjct: 8676 MATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSASLSGMPTG 8735

Query: 576  RSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSS 635
             ++  +  + LS  +    G A+ + S     +     T  +T + T GSA ++ I   +
Sbjct: 8736 ATTKVSRTEALSLGRTSTPGPAQSTISPEISTE---TITRISTPLTTTGSAEMT-ITPKT 8791

Query: 636  GIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVS 695
            G       G  T LD S+ A      PG  S   +RS P    ++ MS      GP  VS
Sbjct: 8792 GHSGASSQGTFT-LDTSSRAS----WPGTHSAATHRS-PHSGMTTPMS-----RGPEDVS 8840

Query: 696  SSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISL 755
                PS+  T      PS L   + V    T+P+P+  T  E   +    V      + +
Sbjct: 8841 WPSRPSVEKTS----PPSSLVSLSAV----TSPSPLYSTPSESSHSSPLRVTSLFTPVMM 8892

Query: 756  K-------------------SIGSPESTPKNQASHPT-ATKLAELPPT----PLRATAKS 791
            K                   +I S ES   ++A+  T A +L+E         + A  + 
Sbjct: 8893 KTTDMLDTSLEPVTTSPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEF 8952

Query: 792  FVKPPSLANLDKVNSN-----------SLDLPSSSDTTHASKVPDLHATSSASGGP---- 836
            +   P L    KV S            S  +P+SS+ T      ++ +TS+ +  P    
Sbjct: 8953 YSSYPGLPEPSKVTSPVVTSSTIKDIVSTTIPASSEITRI----EMESTSTLTPTPRETS 9008

Query: 837  ----LPSCFTPSPAPILNINSASFSQGL-ELMSGFSVPK----------ETRMYPKLSGL 881
                + S   PS  P   + SA+    + ++MS    P            T +  +LS  
Sbjct: 9009 TSQEIHSATKPSTVPYKALTSATIEDSMTQVMSSSRGPSPDQSTMSQDISTEVITRLSTS 9068

Query: 882  HRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRN 941
                ES +M ++  +  P +T   T     +      T      G   +       R   
Sbjct: 9069 PIKTESTEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPG 9128

Query: 942  TLP---------KKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPALPMSLSAK 992
             +P              + L S   T     S T   LP+S   S LP    L   L   
Sbjct: 9129 DVPWLSHPSVEEASSASFSLSSPVMTSSSPVSST---LPDSIHSSSLPVTSLLTSGLVKT 9185

Query: 993  GQLTNIVS-PTAATTPRITRSNS-------IPTHEAAFEL-------YSGSQMGSTLSLA 1037
             +L    S P  ++ P ++ +++       + T     E+       Y+     S L+ +
Sbjct: 9186 TELLGTSSEPETSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADS 9245

Query: 1038 ERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRK--LRRELESSQE 1095
               K     G    PT D +    + A S +S   +  +   +  + +  +  E  S+ E
Sbjct: 9246 VTTKATSSMG-ITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETSSATE 9304

Query: 1096 KVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSE 1155
            K +T+ S +   A    +  +++ +  + +   A++    DT +  +      L +K S 
Sbjct: 9305 K-STVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRKEST 9363

Query: 1156 AQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSS-KDADAKKKKKKSWL 1214
              A+        +T P     +   + DS S+ +   +HS+       +       +   
Sbjct: 9364 DMAI------TPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSRGPE 9417

Query: 1215 RSSFNKAFSIKKG--PKSASSYSDIEE----IATPDSSAPSSP--------KLQHGSTET 1260
              S+    S++K   P S  S S +       +TP  S+ SSP         +   +T+ 
Sbjct: 9418 DVSWPSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATDM 9477

Query: 1261 ASPSIKSSTSSSVGTDVTEGPAHPA----PHTRLFHANEEEEPEKKEVSELRSELWEKE- 1315
               S++  T+S+   ++T   +  A      T   H  E       E +    EL+    
Sbjct: 9478 LDASLEPETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVETTSATEELYSSSP 9537

Query: 1316 --MKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPG 1373
               + T +    + S+   D +  T       +  ++ E+    + PG     T   +  
Sbjct: 9538 GFSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEIES-MSSLTPGLRETRTSQDITS 9596

Query: 1374 SSALSSPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKE-----EVTLRVVVRMPPQH 1428
            S+  S+    +    T    P ++ T++ P    S  GP +     +++  VV R+    
Sbjct: 9597 STETSTVLYKMPSGAT----PEVSRTEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSP 9652

Query: 1429 II 1430
            I+
Sbjct: 9653 IM 9654



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 242/1171 (20%), Positives = 387/1171 (33%), Gaps = 217/1171 (18%)

Query: 295   DSDDANPRSVSSLSNRSSP-----LSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMHG 349
             ++  A PR+  S+ NR S      +S    + SP +Q  D      S   + T +W +H 
Sbjct: 10548 ETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDV----SSSEPDTTASWVIHP 10603

Query: 350   ERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDDITTG 409
                  + T+P  S +  +                     + S+ D +  T T       G
Sbjct: 10604 -----AETIPTVSKTTPNF--------------------FHSELDTVSSTATSH-----G 10633

Query: 410   WDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASR-----------RNSTIVLRT 458
              D SS+I +       N+S  E +A + L ++  T T++               T  L  
Sbjct: 10634 ADVSSAIPT-------NISPSELDALTPLVTISGTDTSTTFPTLTKSPHETETRTTWLTH 10686

Query: 459   DSEKRSLAESGLSWFSESEEKAPKKLEYDSGS--------LKMEPGTSKWRRERPESCDD 510
              +E  S     +  FS  E  A   +    G+        + + PG       +  S   
Sbjct: 10687 PAETSSTIPRTIPNFSHHESDATPSIATSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGT 10746

Query: 511   SSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATD-KGKLAV 569
                       +S G P ++    T P A TS    T+  +  V+       T    K + 
Sbjct: 10747 DRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVTSLAAKTST 10806

Query: 570   KNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLS 629
              N  L  S  +             +    P T+  F + K    + T   M T   A   
Sbjct: 10807 TNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSK----SDTTPSMTTSHGA--- 10859

Query: 630   KIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRG 689
               + SS +P   V+          +  PG + P   S+    S   P  + S        
Sbjct: 10860 --ESSSAVPTPTVS----------TEVPGVVTPLVTSSRAVISTTIPILTLS-------- 10899

Query: 690   GPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALD 749
                P      PS+ +T  G    S +  PT V+ G   P  V           ++AV   
Sbjct: 10900 ---PGEPETTPSM-ATSHGEEASSAIPTPT-VSPG--VPGVVTSL-----VTSSRAVTST 10947

Query: 750   SDNISLKSIGSPESTPKNQASHPTATKLA---ELPPTPLRATAKSFVKPPSLANLDKVNS 806
             +  I   S+G PE+TP    SH T    A    LP  P   T+        +A+   V S
Sbjct: 10948 TIPILTFSLGEPETTPSMATSHGTEAGSAVPTVLPEVPGMVTS-------LVASSRAVTS 11000

Query: 807   NSLDL----PSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLEL 862
              +L      P   +TT    +   H   ++S  P  S   P     L + S+S      +
Sbjct: 11001 TTLPTLTLSPGEPETT--PSMATSHGAEASSTVPTVSPEVPGVVTSL-VTSSSGVNSTSI 11057

Query: 863   MSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEEL 922
              +    P E    P ++  H +               +S+ VPTP   P           
Sbjct: 11058 PTLILSPGELETTPSMATSHGA--------------EASSAVPTPTVSPGV--------- 11094

Query: 923   TWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSP 982
               SG        S      T+P   L       E T     SH +             S 
Sbjct: 11095 --SGVVTPLVTSSRAVTSTTIPI--LTLSSSEPETTPSMATSHGVEA-----------SS 11139

Query: 983   PALPMSLSAKGQLTNIVSP----TAATTPRITRSNSIPTHEAAFELYSGSQMGS---TLS 1035
               L +S    G +T++V+     T+ T P +T S+  P    +   +S ++M S   TL+
Sbjct: 11140 AVLTVSPEVPGMVTSLVTSSRAVTSTTIPTLTISSDEPETTTSLVTHSEAKMISAIPTLA 11199

Query: 1036  LAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQE 1095
             ++   +G++ S      ++    S L++ASS   T  S         +     E  S   
Sbjct: 11200 VSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDS--------WVAHPGTEASSVVP 11251

Query: 1096  KVATLTSQLSANANLV---AAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKK 1152
              +   T +   N +LV   A    +L   TSR  H         +EL  +  T+      
Sbjct: 11252 TLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSH---------SELDTMPSTV-----T 11297

Query: 1153  NSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKS 1212
             + EA++    +   S   P  L     +S   IS+       S   S   A        S
Sbjct: 11298 SPEAESSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESEATA--------S 11349

Query: 1213  WLRSSFNKAFSIKKGPKSASSYSDIEEIATPD-SSAPSSPKLQHGSTETASPSIKSSTSS 1271
             W+    + A +    P++  +YS  E   TP  +++P +       T T SP +    +S
Sbjct: 11350 WVT---HPAVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTS 11406

Query: 1272  SV---GTDV-----TEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEKEMKLTDIRL 1323
              V   GTD      T   +   P T        E      +  L       +M  + +  
Sbjct: 11407 QVTSSGTDTSITIPTLTLSSGEPETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVIS 11466

Query: 1324  EALNSAHQLDQLRETMHNMQLEVDLL--KAENDRLKVAPGPSSGSTPGQVPGSSALSSPR 1381
                +S      L ET +  +     L   AE + +     P    +        A++SP 
Sbjct: 11467 SGTDSTTTFPTLTETPYEPETTAIQLIHPAETNTMVPRTTPKFSHSKSDTTLPVAITSPG 11526

Query: 1382  RSLGLAL-THSFGPSLAD--TDLSPMDGIST 1409
                  A+ T +  P ++D  T L P  G  T
Sbjct: 11527 PEASSAVSTTTISPDMSDLVTSLVPSSGTDT 11557



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 191/939 (20%), Positives = 337/939 (35%), Gaps = 176/939 (18%)

Query: 428  SSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAPKKLEYD 487
            S EE +++SSL SLP+T + S  +ST+V   D    SL  + L             +  D
Sbjct: 8259 SVEETSSASSLLSLPATTSPSPVSSTLV--EDFPSASLPVTSLL-------NPGLVITTD 8309

Query: 488  SGSLKMEPGT------SKWRRERPESCDDSSKGGELK----------KPISLGHPGS--- 528
               +  EPGT      S    ER  + +D+    +++          +    GH      
Sbjct: 8310 RMGISREPGTSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSV 8369

Query: 529  LKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNT-----GLQRSSSDAGR 583
            L   +TP    TSP+  T                +  ++ ++ T     GL+ +SS    
Sbjct: 8370 LSDSETP--KATSPMGTTYTMGETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSS--- 8424

Query: 584  DRLSDA-------KKPPSG----IARPSTSGSFGYK---------KPPPATGTATVMQTG 623
            +R+S A        + PSG    ++R     S G            P  +T   T + T 
Sbjct: 8425 ERISSATEGSTVLSEVPSGATTEVSRTEVISSRGTSMSGPDQFTISPDISTEAITRLSTS 8484

Query: 624  GSAT---LSKIQKSSGIPVKPVNGRKTSLDVS---------NSAEPGF-------LAPGA 664
               T    S I   +G P     G  T LD S         ++A PGF       L    
Sbjct: 8485 PIMTESAESAITIETGSPGATSEGTLT-LDTSTTTFWSGTHSTASPGFSHSEMTTLMSRT 8543

Query: 665  RSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASG 724
              ++ + SLP   ++SS+S           SS   P++ ST      P  +       + 
Sbjct: 8544 PGDVPWPSLPSVEEASSVS-----------SSLSSPAMTSTSFFSTLPESISSSPHPVTA 8592

Query: 725  RTTPAPVNQTDREKEKAKAKAVALDS-DNISLKSIGSPESTPKNQASHPTATKLAELPPT 783
              T  PV  TD  +  ++ +  +  +  + S + + + E T   +  HP+    +  P  
Sbjct: 8593 LLTLGPVKTTDMLRTSSEPETSSPPNLSSTSAEILATSEVTKDREKIHPS----SNTPVV 8648

Query: 784  PLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFTP 843
             +       + P S+           DL ++  T+         AT+S  G    S  TP
Sbjct: 8649 NVGTVIYKHLSPSSVL---------ADLVTTKPTSPM-------ATTSTLGNTSVSTSTP 8692

Query: 844  S-PAPILNINSASFSQGL-ELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSS 901
            + P  ++   ++S + GL E+ +       T     LSG+     +        S   +S
Sbjct: 8693 AFPETMMTQPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRTEALSLGRTS 8752

Query: 902  TPVPTPPA-PPAAPTEEETE---ELTWSGS------PRAGQLDSNQRDRNTLPKKGLRYQ 951
            TP P      P   TE  T     LT +GS      P+ G   ++ +   TL     R  
Sbjct: 8753 TPGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQGTFTLDTSS-RAS 8811

Query: 952  LQSQEETKERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSPTAATTPRITR 1011
                      R  H+    P S    ++ S P+ P S+      +++VS +A T+P    
Sbjct: 8812 WPGTHSAATHRSPHSGMTTPMSRGPEDV-SWPSRP-SVEKTSPPSSLVSLSAVTSPS--- 8866

Query: 1012 SNSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTY 1071
                P +    E    S +  T          + +      TD +  S+  + +S  S  
Sbjct: 8867 ----PLYSTPSESSHSSPLRVT---------SLFTPVMMKTTDMLDTSLEPVTTSPPSMN 8913

Query: 1072 SSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFE--------QSLVNMTS 1123
             +++E + + +       ++ S+    T    +SA     +++          S V  +S
Sbjct: 8914 ITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKVTSPVVTSS 8973

Query: 1124 RLRHLAETAEEKDTEL----LDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQ 1179
             ++ +  T     +E+    ++   T+    ++ S +Q +       S T P  +  K  
Sbjct: 8974 TIKDIVSTTIPASSEITRIEMESTSTLTPTPRETSTSQEI------HSATKPSTVPYKAL 9027

Query: 1180 NSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEE 1239
             S+    S+  + S SS G S D            +S+ ++  S +   + ++S    E 
Sbjct: 9028 TSATIEDSMTQVMS-SSRGPSPD------------QSTMSQDISTEVITRLSTSPIKTES 9074

Query: 1240 IATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGTDVT 1278
                 ++   SP    G+T   + ++ +ST+   GT  T
Sbjct: 9075 TEMTITTQTGSP----GATSRGTLTLDTSTTFMSGTHST 9109



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 199/926 (21%), Positives = 318/926 (34%), Gaps = 95/926 (10%)

Query: 413  SSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSW 472
            S+ +SS  S   + +S     +  SL S  S      R ST  +   +   S+  S    
Sbjct: 281  SAPLSSSASVLDNKISETSIFSGQSLTSPLSPGVPEARAST--MPNSAIPFSMTLSNAET 338

Query: 473  FSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPIS---LGHPGSL 529
             +E        L   S S K    T        E+ D  S    + K ++   LG PG+L
Sbjct: 339  SAERVRSTISSLGTPSISTKQTAETILTFHAFAETMDIPST--HIAKTLASEWLGSPGTL 396

Query: 530  KKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDA 589
                T  +  TSP T              GK T+ G L    T L+ S+   G +    A
Sbjct: 397  GGTSTSALTTTSPSTTLVSEETNTHHSTSGKETE-GTLNTSMTPLETSA--PGEESEMTA 453

Query: 590  KKPP--------SGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKP 641
               P        S I  PS   S    +    TG+ +  Q+  +A       S  +    
Sbjct: 454  TLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHG---SSDILRATT 510

Query: 642  VNGRKTSLDVSNSAEPGFLAPGARSNIQ---YRSLPRPAKSSSMSVTGGRGGPRPVSSSI 698
             +  K S   S S    F  P     ++        RP  S+S++       P  VS   
Sbjct: 511  SSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFT 570

Query: 699  DPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSI 758
                 STK  G+        T +  G +T  P        + A    +++   + +  S 
Sbjct: 571  TLKTSSTK--GIWLEETSADTLI--GESTAGPTTH-----QFAVPTGISMTGGSSTRGSQ 621

Query: 759  GSPESTPKNQASHPTATKLA----ELPPTPLRATAKSFV-------KPPSLANLDKVNSN 807
            G+     +  AS  T+  L      +P +   A +K+           PS   +  V   
Sbjct: 622  GTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPE 681

Query: 808  SLDLPSSS--DTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSAS-FSQGLELMS 864
            +  L SS+  + T     P       +S  P  +  T     I  ++SAS     +   S
Sbjct: 682  TSSLQSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATS 741

Query: 865  GFSVPKETRMY----PKLSGLHRSMESLQMPMSLPSAFPSSTPV--PTPPAPPAAPTEEE 918
             FS  K T       P++S   +   ++   M+L +A  S   V   T P    +P+ EE
Sbjct: 742  TFSHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSGEE 801

Query: 919  TEELTWSGSPRAGQLDS-NQRDRNTLPKKGLR----YQLQSQEETKERRHSHTIG-GLPE 972
            T     + S  A   DS N     TL  +         L S    K    S T    L  
Sbjct: 802  TAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFT 861

Query: 973  SDDQSELPSPPALPMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMGS 1032
            S +++E  S P++    ++  ++   ++ T+  TP     ++ PT  A F   S S + S
Sbjct: 862  SGEETEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQF---SSSHLVS 918

Query: 1033 TLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQS--EQIRKLRREL 1090
             L           +GS       + G+     ++  +   SA  +  +  E   + +  L
Sbjct: 919  ELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQSTTWPETSPRFKTGL 978

Query: 1091 ESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLK 1150
             S+   V+T  + LSA   +V+ F     +        A +  E  T +L    T +   
Sbjct: 979  PSATTTVSTSATSLSATV-MVSKFTSPATSSME-----ATSIREPSTTIL----TTETTN 1028

Query: 1151 KKNSEAQA----------VIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSS 1200
               S A A          + +G L+ S   P       + S D   +  S++   S   S
Sbjct: 1029 GPGSMAVASTNIPIGKGYITEGRLDTSH-LPIGTTASSETSMDFTMAKESVSMSVSPSQS 1087

Query: 1201 KDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTET 1260
             DA       ++   S F   FS          +    EI  P     S+   Q  +T  
Sbjct: 1088 MDAAGSSTPGRT---SQFVDTFS------DDVYHLTSREITIPRDGTSSALTPQMTATHP 1138

Query: 1261 ASPSIKSSTSSSVGTDVTEGPAHPAP 1286
             SP   S+ S+ +G  ++  P+ P P
Sbjct: 1139 PSPDPGSARSTWLGI-LSSSPSSPTP 1163



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 176/881 (19%), Positives = 314/881 (35%), Gaps = 156/881 (17%)

Query: 430   EEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAPKKLEYDSG 489
             E   +SSSL SLP T + S  +ST++  + S    +    L    ++ E      E  + 
Sbjct: 9722  ETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKTTEVLDTSSEPKTS 9781

Query: 490   SLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAV-TSPITHTAQ 548
             S    P  S    E P +        E+       HP S     T    V TS   H + 
Sbjct: 9782  S---SPNLSSTSVEIPAT-------SEIMTDTEKIHPSS----NTAVAKVRTSSSVHESH 9827

Query: 549   SALKVAGKPEGKATDKGKLAVKNTGLQRSSSD----AGRDRLSDAKKPPSGIARPSTSGS 604
             S++         A  +  + + + G+  +  D          S+ ++ P+    P+ S +
Sbjct: 9828  SSV--------LADSETTITIPSMGITSAVDDTTVFTSNPAFSETRRIPT---EPTFSLT 9876

Query: 605   FGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGA 664
              G+++   +  T ++ +T  SA L  +  S+   V       ++      ++   ++P  
Sbjct: 9877  PGFRETSTSEETTSITET--SAVLYGVPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDI 9934

Query: 665   RSNIQYR--SLPRPAKSSSMSVTGGRGGPRPVSSS-----IDPSLLSTKQGGLTPSRLKE 717
              + +  R  S    ++S+ M++T  +  P   + S        + L+     + P  L  
Sbjct: 9935  ITEVITRLSSSSMMSESTQMTITTQKSSPGATAQSTLTLATTTAPLARTHSTVPPRFLHS 9994

Query: 718   PTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGS--PESTPKNQASHPTAT 775
                    R+   P  ++    EK  + +  L     +  S+ S  P+S P +  S    T
Sbjct: 9995  EMTTLMSRSPENPSWKSSLFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFS---VT 10051

Query: 776   KLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGG 835
              L  L P  ++ T  S     SL+    ++  S+++ ++S+ T  +    +H +SS +  
Sbjct: 10052 SL--LTPGMVKTTDTSTEPGTSLS--PNLSGTSVEILAASEVT--TDTEKIHPSSSMA-- 10103

Query: 836   PLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLP 895
                         + N+ +   S G EL S  S+  E        G   SM    +  S+P
Sbjct: 10104 ------------VTNVGTT--SSGHELYSSVSIHSEPSKATYPVGTPSSMAETSISTSMP 10149

Query: 896   SAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLD-SNQRDRNTLPKKGLRYQLQS 954
             + F ++               E    LT         LD S+    NT    G  + LQS
Sbjct: 10150 ANFETT-----------GFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGSTHLLQS 10198

Query: 955   QEETKERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSPTAATTPRITRSNS 1014
              +         +    P +   +E+P     P   +A   +T     T+    R T S +
Sbjct: 10199 SKTDFTSSAKTSSPDWPPASQYTEIPVDIITP--FNASPSITESTGITSFPESRFTMSVT 10256

Query: 1015  IPTHEAAFELYSGSQMGST----LSLAER---------PKGMIRSGSFRDPTDDVHGSVL 1061
               TH  + +L   ++  ST     SL+E          P+ +  SGS    T+   G   
Sbjct: 10257 ESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGDAT 10316

Query: 1062  ------SLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFE 1115
                   SL SS    +SS+              E+ SS      + + L   ++     E
Sbjct: 10317 LSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTESSTT---E 10373

Query: 1116  QSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELR 1175
               LV M S L   ++      + +LD R T           ++V  G + ++   P    
Sbjct: 10374 GRLV-MVSTLDTSSQPGRTSSSPILDTRMT-----------ESVELGTVTSAYQVP---- 10417

Query: 1176  IKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYS 1235
                 + S  ++  + I  H                             I K P  A+   
Sbjct: 10418 ----SLSTRLTRTDGIMEH-----------------------------ITKIPNEAAHRG 10444

Query: 1236  DIEEIATPD-SSAPSSPK-LQHGST---ETASPSIKSSTSS 1271
              I  +  P  S++P+SPK L  G T   ET + ++K++T++
Sbjct: 10445 TIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTTA 10485



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 248/1252 (19%), Positives = 457/1252 (36%), Gaps = 227/1252 (18%)

Query: 283  QVTHSSLEMTCYDSDDANPRS--VSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSE 340
            +VT SS  +   ++ D N  S   SS S +SSP    Y + +P     D  ++  S  + 
Sbjct: 3896 EVTSSSSVLRTLNTLDINLESGTTSSPSWKSSP----YERIAPSESTTDKEAIHPSTNTV 3951

Query: 341  GTPAWYMHGERAHYSHTMPMRSPSK------LSHISRLELVESL------DSDEVDLKSG 388
             T  W    E A +S T+P  S S       ++  +R + + S+      +S     +  
Sbjct: 3952 ETTGWVTSSEHASHS-TIPAHSASSKLTSPVVTTSTREQAIVSMSTTTWPESTRARTEPN 4010

Query: 389  YMSDSDLMGKTMTEDDDITTGWDESSSISSGLSDA------SDNLSSEEFNAS---SSLN 439
                 +L   +   D   TT   ++S ISS  S A      ++  SS+  ++S    S+ 
Sbjct: 4011 SFLTIELRDVSPYMDTSSTT---QTSIISSPGSTAITKGPRTEITSSKRISSSFLAQSMR 4067

Query: 440  SLPSTPTASRRNSTIVLRTDSEKRSLA-----------------ESGLSWFSESEEKAPK 482
            S  S   A  R S     T+S    LA                  S  + ++ +     +
Sbjct: 4068 SSDSPSEAITRLSNFPAMTESGGMILAMQTSPPGATSLSAPTLDTSATASWTGTPLATTQ 4127

Query: 483  KLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSL---KKGKTPPVAV 539
            +  Y   +     G     +  P S +++S    L    +   P ++    +G +P  + 
Sbjct: 4128 RFTYSEKTTLFSKGPEDTSQPSPPSVEETSSSSSLVPIHATTSPSNILLTSQGHSP--SS 4185

Query: 540  TSPITHTAQSALKVAGKPEGKATDKGKLAVK-----------NTGLQRSSSDAGRDRLSD 588
            T P+T    S  + +G   GK TD  +++++             G   S+ +A RD  + 
Sbjct: 4186 TPPVTSVFLS--ETSGL--GKTTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKAI 4241

Query: 589  AKKPPSGIAR-PSTSGSF----GYKKPPPATG---TATVM-------QTGGSATLSKIQK 633
                 + +    +TS  +    G+ KP  AT    T+ +M          GS+  ++I+ 
Sbjct: 4242 HHSADTAVTNMEATSSEYSPIPGHTKPSKATSPLVTSHIMGDITSSTSVFGSSETTEIET 4301

Query: 634  SSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSN--IQYRSLPRPAKSSSMSVTG----- 686
             S +  + +  R TS   S++ E   +     S     + +  +   SS  S++      
Sbjct: 4302 VSSVN-QGLQERSTSQVASSATETSTVITHVSSGDATTHVTKTQATFSSGTSISSPHQFI 4360

Query: 687  -GRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRT-----------TPAPVNQT 734
                    VS++   SL+ T+  G+T +    PT  A+              T  P+  T
Sbjct: 4361 TSTNTFTDVSTNPSTSLIMTESSGVTITTQTGPTGAATQGPYLLDTSTMPYLTETPLAVT 4420

Query: 735  DREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVK 794
                +  K   ++    ++S  S  S   T     S+P++        TP   T      
Sbjct: 4421 PDFMQSEKTTLISKGPKDVSWTSPPSVAET-----SYPSSL-------TPFLVTTI---- 4464

Query: 795  PPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSA 854
            PP+ + L   +++S    +S  T+   K  D+  TS           T SP    N+N+ 
Sbjct: 4465 PPATSTLQGQHTSSPVSATSVLTSGLVKTTDMLNTSMEP-------VTNSPQ---NLNNP 4514

Query: 855  SFSQGLELMSGFSVPKETR-MYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAP--P 911
            S     E+++  +   +   ++P ++    +M +      L S  P S+   T  +P  P
Sbjct: 4515 SN----EILATLAATTDIETIHPSINKAVTNMGTASSAHVLHSTLPVSSEPSTATSPMVP 4570

Query: 912  AAPTEEETEELTWSGSPRA-------GQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHS 964
            A+   +    ++  GS            L + +++ +TL       ++ S  E+     +
Sbjct: 4571 ASSMGDALASISIPGSETTDIEGEPTSSLTAGRKENSTLQ------EMNSTTESNIILSN 4624

Query: 965  HTIGGLPESDDQSELPSPPALPMSLSAKG----QLTNIVSPTAATTPRITRSNSIPTHEA 1020
             ++G + E+  + E+PS  A  +   A+      + ++ S   + +P +T S  + T   
Sbjct: 4625 VSVGAITEAT-KMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSNSPPMTISTHMTT--- 4680

Query: 1021 AFELYSGSQMGSTLSLAERPKGMIRSG---SFRDPTDDVHGSVLSLASSASSTYSSAEER 1077
                   +Q GS+ + ++ P  +  S    S   P+    G     A S  +T  + + +
Sbjct: 4681 -------TQTGSSGATSKIPLALDTSTLETSAGTPSVVTEG----FAHSKITTAMNNDVK 4729

Query: 1078 MQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQ--SLVNMTSRLRH-LAETAEE 1134
              S+     + E  S   +   L + L ++      +    S V+M+S L   L +TA +
Sbjct: 4730 DVSQTNPPFQDEASSPSSQAPVLVTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGK 4789

Query: 1135 KDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSH 1194
             DT L    ET+       S  Q++     + S T+     I+  + S +    N  T+ 
Sbjct: 4790 VDTSL----ETV------TSSPQSMSNTLDDISVTSAATTDIETTHPSINTVVTNVGTTG 4839

Query: 1195 SSIGSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQ 1254
            S+  S     A  +  K                  S +  +   E  T   S P S K  
Sbjct: 4840 SAFESHSTVSAYPEPSKV----------------TSPNVTTSTMEDTTISRSIPKSSKTT 4883

Query: 1255 HGSTETASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEK 1314
               TET S        +S+  ++T              + E      KE++   +     
Sbjct: 4884 RTETETTSSLTPKLRETSISQEITS-------------STETSTVPYKELTGATT----- 4925

Query: 1315 EMKLTDIRLEALNSAHQLDQLR-----ETMHNMQLEVDLLKAENDRLKVA--PGPSSGST 1367
            E+  TD+   +  S    DQ        T  N +L    +  E+  + +    GP   ++
Sbjct: 4926 EVSRTDVTSSSSTSFPGPDQSTVSLDISTETNTRLSTSPIMTESAEITITTQTGPHGATS 4985

Query: 1368 PGQVPGSSALSSPRRSLGLALTHSFGPSLADTDLS--PMDGISTCGPKEEVT 1417
                    + ++P+  +  A+TH F      T +S  P D   T  P  + T
Sbjct: 4986 QDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKT 5037



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 216/1095 (19%), Positives = 375/1095 (34%), Gaps = 168/1095 (15%)

Query: 268  LRQNLEETMSSLRGSQVTHSSLEMTCYDSDDANP--RSVSSLSNRSSPLSWRYGQSSPRL 325
            LR  LE   SSL     T   +  T  DS D      S+++        +  +   SP L
Sbjct: 5083 LRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPAL 5142

Query: 326  QAGDAPSVGGSC---RSEGTPAWYMHGERAHYSHTMPMRSPSKLSHISRLE---LVESLD 379
               + P          + G PA          S +MP+   S+ ++I R     L   L 
Sbjct: 5143 ADSETPKATTQMVITTTVGDPA---------PSTSMPVHGSSETTNIKREPTYFLTPRLR 5193

Query: 380  SDEVDLKSGYMSDSD-LMGK--TMTEDDDITTGWDESSSISSGLSDASDNLSSEEFNASS 436
                  +S + +D+  L+ K  T T  +  +TG + SS IS+   D S  +  + F    
Sbjct: 5194 ETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTPDHDKS-TVPPDTFTGE- 5251

Query: 437  SLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPG 496
                +P   T+S       ++T S + ++        S  E  +   L  D+ +   + G
Sbjct: 5252 ----IPRVFTSS-------IKTKSAEMTITTQA----SPPESASHSTLPLDTSTTLSQGG 5296

Query: 497  TSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGK 556
            T         +        E+   + +G PG++    TPPV  TS ++    S    +  
Sbjct: 5297 THS-------TVTQGFPYSEVTTLMGMG-PGNVSWMTTPPVEETSSVSSLMSSPAMTSPS 5348

Query: 557  PEGKATDKG--KLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPAT 614
            P    + +      +  T L  S      D L     P S  + P    S  +++P    
Sbjct: 5349 PVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLG-TTSPESVTSSPPNLSSITHERPATYK 5407

Query: 615  GTA--------------TVMQTGG------SATLSKIQKSSGIPVKPVNGRKTSLDVSNS 654
             TA              T + T G      S+ L+  + S   P+           VS S
Sbjct: 5408 DTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTS 5467

Query: 655  AEPGF-------LAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQ 707
              P           P A  + + R      K+SS + T       P  +    S      
Sbjct: 5468 T-PNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISS 5526

Query: 708  GGLTPSRLKEPT---KVASG----------RTTPAPVNQTDREKEKAKAKAVALDSDNIS 754
               + S L  PT    +++G           T  A +  T +           L  D  +
Sbjct: 5527 SRTSISDLDRPTIAPDISTGMITRLFTSPIMTKSAEMTVTTQTTTPGATSQGILPWDTST 5586

Query: 755  LKSIGSPESTPKNQASHPTATKLAELPP--------TPLRATAKSF-VKPPSLANLDKVN 805
                G   ST      H   T L    P         P+  T+  F +  PS+ +   V+
Sbjct: 5587 TLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPSMTSPSPVS 5646

Query: 806  SNSLD-LPSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMS 864
            S S + +PSS     A     L  T++  G   P   T SP                   
Sbjct: 5647 STSPESIPSSPLPVTALLTSVLVTTTNVLGTTSPEPVTSSP------------------P 5688

Query: 865  GFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPS-STPVPTPPAPPAAPTEEETEELT 923
              S P + R+       H   E++   M   +A  +  T +    +  + P +  T + T
Sbjct: 5689 NLSSPTQERLTTYKDTAH--TEAMHASMHTNTAVANVGTSISGHESQSSVPADSHTSKAT 5746

Query: 924  WSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEET------KERRHSHTIGGLPE-SDDQ 976
               SP            +T        ++Q++  +      ++ R S  I  + E S   
Sbjct: 5747 ---SPMGITFAMGDTSVSTSTPAFFETRIQTESTSSLIPGLRDTRTSEEINTVTETSTVL 5803

Query: 977  SELPSPPALPMSLS--AKGQLTNIVSPTAA------TTPRITRSNSIPTHEAAFELYSGS 1028
            SE+P+     +S +       T I  P  +      +T  ITR ++ P    + E+   +
Sbjct: 5804 SEVPTTTTTEVSRTEVITSSRTTISGPDHSKMSPYISTETITRLSTFPFVTGSTEMAITN 5863

Query: 1029 QMGSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERM-QSEQIRKLR 1087
            Q G        P G I   +    T        S  +S   T+S   +R   SE+   + 
Sbjct: 5864 QTG--------PIGTISQATLTLDT--------SSTASWEGTHSPVTQRFPHSEETTTMS 5907

Query: 1088 RELES-SQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELL--DLRE 1144
            R  +  S +   ++    S ++ +      S  ++ S +   + T+    T LL    R+
Sbjct: 5908 RSTKGVSWQSPPSVEETSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRK 5967

Query: 1145 TIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDAD 1204
            TID L   ++ ++ V     +AS  + + L  +   ++++I   +  T+ +++G++    
Sbjct: 5968 TIDML---DTHSELVTSSLPSASSFSGEILTSEASTNTETI-HFSENTAETNMGTT---- 6019

Query: 1205 AKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPS 1264
                  K     S +   S    PK   S  +   ++T    +P +  +   ST   +P 
Sbjct: 6020 --NSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPE 6077

Query: 1265 IKSSTSSSVGTDVTE 1279
            +K  +++ V    TE
Sbjct: 6078 LKEDSTALVMNSTTE 6092



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 208/995 (20%), Positives = 336/995 (33%), Gaps = 155/995 (15%)

Query: 405  DITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLP-----STPTASRRN-------- 451
            D+TT    ++  S+ LS+A  +  S   N SS+    P     ST  A +RN        
Sbjct: 2054 DLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGP 2113

Query: 452  ---STIVLRTD-SEKRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPES 507
               +   L TD S    L+E+ +     SE   P  +   S       G +      P  
Sbjct: 2114 QNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAITSRSDV----SGLTSESTANPSL 2169

Query: 508  CDDSSKGGELKKPISLGHPGSL---KKGKTP-PVAV---TSPITHTAQSALKVAGKPEGK 560
               SS G +L + ISL    SL   +  K P  V++   + P T+T  S    +  P G 
Sbjct: 2170 GTASSAGTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIPVNSAGPPGL 2229

Query: 561  ATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPP--ATGTAT 618
            +T    +          +   G + +      PS     +T   F  K         + T
Sbjct: 2230 STVASDVI--------DTPSDGAESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISSLT 2281

Query: 619  VMQTGGSATLSKIQKSSGIPVKPVNG--------RKTSLDVSNSAEPGFLAPGARSNIQY 670
               T     +     SS +  KP           R+T    + +  P  L          
Sbjct: 2282 HELTSRVTPIPGDWMSSAMSTKPTGASPSITLGERRTITSAAPTTSPIVLTASFTETSTV 2341

Query: 671  RSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLK----EPTKVASGRT 726
                     +S  +   +    P  SS    L++T     T    K     PT ++    
Sbjct: 2342 SLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMTA 2401

Query: 727  TPAP-VNQTDREK------EKAKAKAVALDSDNISLKSI----GSPESTPKNQASHPTAT 775
            + +P +  +DR +      E   A + ++ S+  SL       G+P + P    +HP  T
Sbjct: 2402 SSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVET 2461

Query: 776  KLAELPPTPLRATAKSFVKPPSLANLDKVNSNSL--DLPSSSDTTHASKVPDLHATSSAS 833
              A L  +    T  + V   + +  +  +SNS+   +P+    T      DL A     
Sbjct: 2462 SSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLK 2521

Query: 834  GGPL-------------PSCFTPS-PAPILNINSASFSQGLELMSGFSVPKETRMYPKLS 879
              P               + FTP   A ++  +SA+    L   S       +   P   
Sbjct: 2522 TSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPTTP 2581

Query: 880  GLHRSMESLQMPMSL-----------------------------PSAFPSS--------- 901
                + E+   P SL                             PS FPS+         
Sbjct: 2582 TSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFP 2641

Query: 902  TPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQ---------L 952
            T +P  PA P   TE  +   T   S     + S+     T+P+  L            L
Sbjct: 2642 TLLPDTPAIPLTATEPTSSLATSFDSTPLVTIASD--SLGTVPETTLTMSETSNGDALVL 2699

Query: 953  QSQEETKERRHSHTIGGLPES--DDQSELPSPPALPMSLSAKGQLTNIVSP-TAATTPRI 1009
            ++           TI G+ ES     S  PS    P + + +G +T  +S   A TT  +
Sbjct: 2700 KTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGTTGSL 2759

Query: 1010 TRSNSIPTHE--AAFELYSGSQMGSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSA 1067
              S S    E  A  +  +G +  S + L    +GM  SG  R  +   H +     SS 
Sbjct: 2760 VFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIR--SGSTHSTGTKTFSSL 2817

Query: 1068 SSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRH 1127
              T +  E    SE I   R     S           SA + L+     S    +S  + 
Sbjct: 2818 PLTMNPGEVTAMSE-ITTNRLTATQSTAPKGIPVKPTSAESGLLTPVSAS----SSPSKA 2872

Query: 1128 LAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISS 1187
             A       T  +  + T+ F   + SE  ++     +AS  TP +       S ++I  
Sbjct: 2873 FASLTTAPPTWGIP-QSTLTF---EFSEVPSL--DTKSASLPTPGQ-------SLNTIPD 2919

Query: 1188 LNSITSHSSIGSS--KDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDS 1245
             ++ T+ SS+  S  K+  A+       + +S  ++    + P+ ++S S         +
Sbjct: 2920 SDASTASSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRVPT 2979

Query: 1246 SAPSSPKLQHGSTETASPSIKSS--TSSSVGTDVT 1278
            S    P+    S     PS  SS  TS+S+ + +T
Sbjct: 2980 SGTGDPRYASESMSYPDPSKASSAMTSTSLASKLT 3014



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 139/694 (20%), Positives = 253/694 (36%), Gaps = 111/694 (15%)

Query: 672  SLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQ---GGLTPSRLKEPTKVASGRTTP 728
            S+ + + SSS+  +     P PVSS++  ++ +T       LTPS +     +    T+P
Sbjct: 6795 SIEKTSFSSSLMPSPAMTSP-PVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLG---TSP 6850

Query: 729  APVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRAT 788
             P   +         + +  D D  ++            +A HP+ +  A    T +  T
Sbjct: 6851 EPTTSSPPNLSSTSHEILTTDEDTTAI------------EAMHPSTSTAA----TNVETT 6894

Query: 789  AKSFVKPPS-LANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAP 847
            +       S LA+ +K  + +  + ++S   H +    +  +S  +     S ++ +P  
Sbjct: 6895 SSGHGSQSSVLADSEKTKATA-PMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPG- 6952

Query: 848  ILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVP-- 905
               +   S SQ     +  S+          + + R+  +     S+P     ST +P  
Sbjct: 6953 ---LRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGP-SQSTVLPEI 7008

Query: 906  ---TPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERR 962
               T     A+PT  E+ E+T     + G   S  +D  TL     + Q ++     +R 
Sbjct: 7009 STRTMTRLFASPTMTESAEMTIP--TQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRF 7066

Query: 963  HSHTIGGL-------------PESDDQSELPS----------PP---ALPMSLSAKG-QL 995
                +  L             P  ++ S LPS          PP    LP+++S+    +
Sbjct: 7067 PHSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPV 7126

Query: 996  TNIVSPTAATTPR--------ITRSNSIPTHEAAFELYSGSQMGSTLSLAERPKGM---- 1043
            T++++ +  TT          +T S    +H +   L +G    +T ++           
Sbjct: 7127 TSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNV 7186

Query: 1044 -IRSGSFRDPTDDVHGSVLSLASSASSTYSSAEE--------------RMQSEQIRKLRR 1088
             I S     P+  +  S  S A+S     S+ E+              R+Q E I  L  
Sbjct: 7187 EIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISSLSP 7246

Query: 1089 ELESSQEKVATL----TSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRE 1144
            +L  +   V T     TS + +  ++ A  E S   +TS  R     + E  T L ++  
Sbjct: 7247 KLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAES-TMLPEIST 7305

Query: 1145 TIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDAD 1204
            T   +K   S   A       +SE T K       ++S+S  +L++ T+ S + +     
Sbjct: 7306 TRKIIKFPTSPILA------ESSEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMT 7359

Query: 1205 AKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPS 1264
             +         S      S   G     S   +EE + P S    S  +      +  P+
Sbjct: 7360 QRLP------HSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSAMISPSPVSSTLPA 7413

Query: 1265 IKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEE 1298
               S+S+SV + +T G       T +  A+ E E
Sbjct: 7414 SSHSSSASVTSLLTPGQVKT---TEVLDASAEPE 7444



 Score = 40.8 bits (94), Expect = 0.013
 Identities = 146/754 (19%), Positives = 276/754 (36%), Gaps = 164/754 (21%)

Query: 333  VGGSCRSEGTPAWYMHGERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSD 392
            +G S  +  + A  +  E +    T+     +  + IS    V+ +     D+ S   + 
Sbjct: 3638 IGTSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTP 3697

Query: 393  SDLMGK----TMTEDDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTAS 448
            S    +    +M   D  +T  D ++ +S+ L D+   LS+ +++   SL+S  +T +A 
Sbjct: 3698 SSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDS---LSTLDWDTGRSLSSATATTSAP 3754

Query: 449  RRNSTIVLRTDSEKRSLAESGLSWFSESEEKA--PKKLEYDSGSLKMEPGTSKWRRERPE 506
            +  +T    T     S A S L +       A  P  +   SG     P  +  + E+  
Sbjct: 3755 QGATTPQELTLETMISPATSQLPFSIGHITSAVTPAAMARSSGVTFSRPDPTSKKAEQTS 3814

Query: 507  SCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGK 566
            +        +L    S  HPG + +     + V   I HTA++       P+     +G+
Sbjct: 3815 T--------QLPTTTS-AHPGQVPRSAATTLDV---IPHTAKT-------PDATFQRQGQ 3855

Query: 567  LAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSA 626
             A+  T   R++SD+  ++                      K  P A     +M +    
Sbjct: 3856 TAL--TTEARATSDSWNEK---------------------EKSTPSAPWITEMMNSVSED 3892

Query: 627  TLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTG 686
            T+ ++  SS + ++ +N    +LD++       L  G  S+  ++S P    + S S T 
Sbjct: 3893 TIKEVTSSSSV-LRTLN----TLDIN-------LESGTTSSPSWKSSPYERIAPSESTTD 3940

Query: 687  GRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAV 746
             +    P +++++ +   T     + S +  P   AS + T   V  + RE+        
Sbjct: 3941 -KEAIHPSTNTVETTGWVTSSEHASHSTI--PAHSASSKLTSPVVTTSTREQAI------ 3991

Query: 747  ALDSDNISLKSIGSPESTPKNQASHPTAT-KLAELPPTPLRATAKSFVKPPSLANLDKVN 805
                  +S+ +   PEST      +   T +L ++ P                  +D  +
Sbjct: 3992 ------VSMSTTTWPESTRARTEPNSFLTIELRDVSPY-----------------MDTSS 4028

Query: 806  SNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSG 865
            +    + SS  +T  +K P    TSS                   I+S+  +Q +     
Sbjct: 4029 TTQTSIISSPGSTAITKGPRTEITSSK-----------------RISSSFLAQSMR---- 4067

Query: 866  FSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWS 925
             S    +    +LS      ES  M +++ ++ P +T +       +APT + +   +W+
Sbjct: 4068 -SSDSPSEAITRLSNFPAMTESGGMILAMQTSPPGATSL-------SAPTLDTSATASWT 4119

Query: 926  GSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPAL 985
            G+P A        ++ TL  KG                       PE   Q   PSPP++
Sbjct: 4120 GTPLATTQRFTYSEKTTLFSKG-----------------------PEDTSQ---PSPPSV 4153

Query: 986  PMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHE---AAFELYSGSQMGSTLSLAERPKG 1042
                S+   L  I + T+ +   +T     P+      +  L   S +G T  +      
Sbjct: 4154 E-ETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVFLSETSGLGKTTDM------ 4206

Query: 1043 MIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEE 1076
               S    +P   +  ++ S A  A STY ++ +
Sbjct: 4207 ---SRISLEPGTSLPPNLSSTAGEALSTYEASRD 4237



 Score = 40.8 bits (94), Expect = 0.013
 Identities = 132/724 (18%), Positives = 254/724 (35%), Gaps = 75/724 (10%)

Query: 613  ATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRS 672
            +T   T + T  +  LSK+   +   V     R  ++  S ++  G        +I   +
Sbjct: 7548 STSEETSLATEANTVLSKVSTGATTEVS----RTEAISFSRTSMSGPEQSTMSQDISIGT 7603

Query: 673  LPRPAKSS------SMSVTGGRGGPRPVSSSIDPSL-LSTKQGGLTPSRLKEPTKVASGR 725
            +PR + SS       M++T   G   P  S+++ +L L+T     TPS ++  + V  G 
Sbjct: 7604 IPRISASSVLTESAKMTITTQTG---PSESTLESTLNLNT---ATTPSWVETHSIVIQGF 7657

Query: 726  TTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATK-LAELPPTP 784
              P       R        +     +        SP S P   + HP +T  LA +PP+P
Sbjct: 7658 PHPEMTTSMGRGPGGVSWPSPPFVKET---SPPSSPLSLPAVTSPHPVSTTFLAHIPPSP 7714

Query: 785  LRATAKSFVKPPSLANL-----DKVNSNSLDLPSSS--------DTTHASKVPDLHATSS 831
            L  T+     P +  ++     +   S+S  L ++S        DT H   V   H +++
Sbjct: 7715 LPVTSLLTSGPATTTDILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAV---HPSTN 7771

Query: 832  ASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMP 891
              G  + +  +   +    +  +S       M   SV   T  + +   +   + S   P
Sbjct: 7772 TGGTNVATTSSGYKSQSSVLADSSPMCTTSTMGDTSVLTSTPAFLETRRIQTELASSLTP 7831

Query: 892  MSLPSAFPSSTPVPT------PPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPK 945
                S+    T   T         P  A TE   E++T    P    +  +   R     
Sbjct: 7832 GLRESSGSEGTSSGTKMSTVLSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSWF 7891

Query: 946  KGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPALPMSLS--AKGQLTNIVSPTA 1003
                   +S E T    H+  +G   +     +  S  +L M+ S  ++G   + +S   
Sbjct: 7892 STSPVMTESAEITM-NTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTLM 7950

Query: 1004 ATTPRITRSNSIPTHE---AAFELYS----------GSQMGSTLSLAERPKGMIRSGSFR 1050
               P      S P  E    +F L S           S +  ++S +  P   + +    
Sbjct: 7951 RRGPEDVSWMSPPLLEKTRPSFSLMSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLA 8010

Query: 1051 DPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANL 1110
              TD +H S   + +S ++  S++ E + + ++     +   S  +  T     S+    
Sbjct: 8011 KTTDMLHKSSEPVTNSPANLSSTSVEILATSEVTTDTEKTHPSSNRTVTDVGTSSSGHES 8070

Query: 1111 VAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASETT 1170
             +               LA++   K T  + +  T++      S         +    T+
Sbjct: 8071 TSFV-------------LADSQTSKVTSPMVITSTMEDTSVSTSTPGFFETSRIQTEPTS 8117

Query: 1171 PKELRIKRQNSSDSISSLNSI-TSHSSIGSSKDADAKKKKKKSWLRSSFNKAFSIKKGPK 1229
               L +++ +SS+  S    + T  S + +   A+  + +  S  R+S +    +   P+
Sbjct: 8118 SLTLGLRKTSSSEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRTSISGFAQLTVSPE 8177

Query: 1230 SASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGTDVTEGPAHPAPHTR 1289
              +S   I  + T      S+  +    T+    + +S+ +  + T       H     R
Sbjct: 8178 --TSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDISTTPNWVETHSTVTQR 8235

Query: 1290 LFHA 1293
              H+
Sbjct: 8236 FSHS 8239



 Score = 38.9 bits (89), Expect = 0.048
 Identities = 89/426 (20%), Positives = 156/426 (36%), Gaps = 62/426 (14%)

Query: 662   PGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKV 721
             P   S+   R+  R + S   ++      P   SSS   + +S    G+  S +      
Sbjct: 11270 PAESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAISTTISPGIPGVLTSLV-----T 11324

Query: 722   ASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTAT-KLAEL 780
             +SGR   A          +++A A  +    ++  ++  P +TP    S P  T  +A  
Sbjct: 11325 SSGRDISATFPTVPESPHESEATASWVTHPAVTSTTV--PRTTPNYSHSEPDTTPSIATS 11382

Query: 781   PPTPLRATAKSFVKPPSLANL--DKVNSNSLD---------LPSSSDTTHASKVPDLHAT 829
             P     +   +    P + ++   +V S+  D         L S    T  S +      
Sbjct: 11383 PGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTSFITYSETH 11442

Query: 830   SSASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGL---HRSME 886
             +S++   LP     SP     + S   S G +  + F    ET   P+ + +   H +  
Sbjct: 11443 TSSAIPTLPV----SPGASKMLTSLVISSGTDSTTTFPTLTETPYEPETTAIQLIHPAET 11498

Query: 887   SLQMPMSLP--SAFPSSTPVP---TPPAPPAAPTEEET------EELTWSGSPRAGQLDS 935
             +  +P + P  S   S T +P   T P P A+     T       +L  S  P +G   S
Sbjct: 11499 NTMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTS 11558

Query: 936   NQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGL------------------PESDDQS 977
                   TL +     +  +   T     S T+ G                   P  D +S
Sbjct: 11559 TTFP--TLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRS 11616

Query: 978   ELPS---PPALPMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMGSTL 1034
              +P+   PP++P  +++  Q+T+  + T+   P +T S   P   A+   + G+Q G T+
Sbjct: 11617 GVPTTTIPPSIPGVVTS--QVTSSATDTSTAIPTLTPSPGEPETTASSATHPGTQTGFTV 11674

Query: 1035  SLAERP 1040
              +   P
Sbjct: 11675 PIRTVP 11680



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 203/1062 (19%), Positives = 380/1062 (35%), Gaps = 198/1062 (18%)

Query: 398  KTMTEDDDITTGWDESSSIS---SGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTI 454
            K  + +  + T    SSS S   + L+ A       +   +   + +PS  T S    T 
Sbjct: 2851 KPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSASLPTP 2910

Query: 455  VLRTDSEKRSLAESGLSWFSESEEKAPK-KLEYDSGSLKMEPGTSKWRRERPE-SCDDSS 512
                ++   S A +  S  S+S EK P+ ++   + ++      S    E PE S   S 
Sbjct: 2911 GQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTETPEGSASPSM 2970

Query: 513  KGGELKKPIS-LGHP--GSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAV 569
             G E + P S  G P   S       P   +S +T T+ ++        G+A   G  + 
Sbjct: 2971 AGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSS 3030

Query: 570  --------KNTGLQRSSSDAGRDRL----SDAKKPPSGI--------ARPSTSGSFGYKK 609
                    + + L  ++S + +  L    S A++P   +          P+++ +   ++
Sbjct: 3031 PISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEE 3090

Query: 610  PPPATGTATVMQTGGSA------TLSKIQKSSGI-----PVKPVNGRKTSLDVSNSA--- 655
            PP  T + T+ +  G+       T +  +  + +     P +P   RK+S +   S+   
Sbjct: 3091 PPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARRKSSPETWASSISV 3150

Query: 656  ---------EPGFLAPGARSNIQYR----SLPRPAKSSSMSVTGGRGGPRPVSSSIDPSL 702
                       G L    + + Q      + P PA+ +  S  G   G   +S+++   +
Sbjct: 3151 PAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPEMSTTL--KI 3208

Query: 703  LSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPE 762
            +S+K+  ++P      T   S   TP      +   E    ++ AL S + S+  + +  
Sbjct: 3209 MSSKEPSISPEI--RSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLPTGT 3266

Query: 763  STP-KNQASHPTATKLAELPPTPLRATAKSFVKPP--SLANLDKVNSNSLDLPSSSDTT- 818
            ++P K+   +  AT+   L P+P  A    +   P  +  +L  ++S SL+ P++   T 
Sbjct: 3267 TSPTKSPTENMLATERVSLSPSPPEAWTNLYSGTPGGTRQSLATMSSVSLESPTARSITG 3326

Query: 819  ---------------------HASK---VPDLHATSSASGGPLPSCFTPSPAPILNINSA 854
                                 H S      D H + S S   L    T SP  + ++   
Sbjct: 3327 TGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDPVT-SPNSVSSLTDK 3385

Query: 855  SFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTP---VPTPPAPP 911
            S  +    +S  ++P        ++   ++  S+    S  S++   T    +    +P 
Sbjct: 3386 SKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDITLGASPD 3445

Query: 912  AAPTEEET---------------EELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQE 956
               T   T               + +T   +P  G+  S      T P  GL   L++  
Sbjct: 3446 VTNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSS--ASSVTSPSIGLE-TLRANV 3502

Query: 957  ETKERRHSHTIGGLPESDDQSELP-------SPPALPMSLSAKGQLTNIVSPTAA----- 1004
               +   + T G L ++   +E+          P +  +++  G  TN +S T       
Sbjct: 3503 SAVKSDIAPTAGHLSQTSSPAEVSILDVTTAPTPGISTTITTMG--TNSISTTTPNPEVG 3560

Query: 1005 -----TTPRITRSNSIPTHE------AAFELYSGSQMGSTLSLAERP--------KGMIR 1045
                 +TP   R  +   H       AA + ++ + M S L +A  P           + 
Sbjct: 3561 MSTMDSTPATERRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSPGTISTMHTTSFLA 3620

Query: 1046 SGSFRDPTDDVHGSVLSLASS---------ASSTYSSAEERMQSEQIRKLRRELE--SSQ 1094
            S +  D     HG +  + +S         A  T +S  ER  S         +   S  
Sbjct: 3621 SSTELDSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRV 3680

Query: 1095 EKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTEL----LDLRETIDFLK 1150
            ++++     + + +   ++ E   V ++      A T  + +T L     D   T+D+  
Sbjct: 3681 QRMSISVPDILSTSWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDT 3740

Query: 1151 KKNSEAQAVIQGALNASETTPKELRIKRQNS---SDSISSLNSITS---------HSSIG 1198
             ++  +      A   + TTP+EL ++   S   S    S+  ITS          S + 
Sbjct: 3741 GRSLSSATATTSAPQGA-TTPQELTLETMISPATSQLPFSIGHITSAVTPAAMARSSGVT 3799

Query: 1199 SSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDI--------------------- 1237
             S+     KK +++  +     +    + P+SA++  D+                     
Sbjct: 3800 FSRPDPTSKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALT 3859

Query: 1238 -EEIATPDS------SAPSSPKLQHGSTETASPSIKSSTSSS 1272
             E  AT DS      S PS+P +       +  +IK  TSSS
Sbjct: 3860 TEARATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSS 3901



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 205/955 (21%), Positives = 329/955 (34%), Gaps = 175/955 (18%)

Query: 441  LPSTPTASRRNSTIVLRTD----------SEKRSLAESGLSWFSES--EEKAPKKLEYDS 488
            +P++PT    +ST+ L +D          SE+ ++     +W S S  EE A   L+  S
Sbjct: 1421 IPTSPTIG--SSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISS 1478

Query: 489  GSLKME----------PGTSKWRRERPESCDDSSKGGELKKPI---SLGHPGSLKKGKTP 535
             S  M           P     + E   S   ++    L + +   SLG  G L      
Sbjct: 1479 PSSPMSTFAIFPPMSTPSHELSKSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPIT 1538

Query: 536  PVAVT-------------------SPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQ- 575
            P+  T                   SP TH  QS       P   +           G Q 
Sbjct: 1539 PLTTTWTSVIEHSTQAQDTLSATMSP-THVTQSLKDQTSIPASASPSHLTEVYPELGTQG 1597

Query: 576  RSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSA--------- 626
            RSSS+A     +  K     ++R   +G    +  PP   T T   + G           
Sbjct: 1598 RSSSEA----TTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIG 1653

Query: 627  TLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTG 686
            T S  + S+ + ++    R ++  VS +   G L   A      +SL R +   S S T 
Sbjct: 1654 TSSPAETSTNMALER---RSSTATVSMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTTE 1710

Query: 687  GRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKV-ASGRTTPAPVNQTDREKEKAKAKA 745
            G        SS   S     QG    S   EP+    S  +T  P+  +    +      
Sbjct: 1711 G-----VTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTTPD-----V 1760

Query: 746  VALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVN 805
              +       K + +  ++  +++S  T +  A L  T L +T  +          +K+ 
Sbjct: 1761 EFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENT--------GKEKLR 1812

Query: 806  SNSLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSG 865
            + S+DLPS +        P +  T   S        T S AP    +S   S G+   S 
Sbjct: 1813 TASMDLPSPT--------PSMEVTPWIS-------LTLSNAPNTT-DSLDLSHGVHTSSA 1856

Query: 866  FSVPKE-------TRMYPKLSGLHRSMESLQMPMSLPSAFP-------SSTPVPTPPAPP 911
             ++  +       TR     +G   S +SL M  S  ++         SS+  P P    
Sbjct: 1857 GTLATDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPET-- 1914

Query: 912  AAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLP 971
            +AP  E T  LT +   RA  L        TLP   +           E   S  I   P
Sbjct: 1915 SAPGAETT--LTSTPGNRAISL--------TLPFSSIPV---------EEVISTGITSGP 1955

Query: 972  ESDDQSELPSPPALPMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMG 1031
            + +      SP   P           IV  +  T  + T+    P H  + E  S  Q  
Sbjct: 1956 DINSAPMTHSPITPP----------TIVWTSTGTIEQSTQ----PLHAVSSEKVS-VQTQ 2000

Query: 1032 STLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAE-ERMQSEQIRK----- 1085
            ST  +           S        H + +S  SS SS YSSA  E + S   R+     
Sbjct: 2001 STPYV----------NSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITS 2050

Query: 1086 ----LRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLD 1141
                L   L ++     +L+  LS+  + V+    +              A++++ E   
Sbjct: 2051 WLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETET 2110

Query: 1142 LRETIDFLKKKNSEAQAVI---QGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIG 1198
                       N++A +V    +  + AS ++   L +   + SD     +  T++ S+G
Sbjct: 2111 HGPQNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPSLG 2170

Query: 1199 SSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGST 1258
            ++  A  K  +  S   S    +F + K P + S           ++S P +     G +
Sbjct: 2171 TASSAGTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIPVNSAGPPGLS 2230

Query: 1259 ETASPSI--KSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSEL 1311
              AS  I   S  + S+ T V+  P+     T + H  E+     + +S L  EL
Sbjct: 2231 TVASDVIDTPSDGAESIPT-VSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHEL 2284



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 71/323 (21%), Positives = 117/323 (36%), Gaps = 42/323 (13%)

Query: 536   PVAVTSPITHTAQSALKVA--GKPE---GKATDKGKLAVKNTGLQRSSSDAGRDRLSDAK 590
             PV  TSP T  + + L     G PE    + T  G  A  +T +   +   G   + +  
Sbjct: 11717 PVMATSPRTEASSAVLTTISPGAPEMVTSQITSSG--AATSTTVPTLTHSPG---MPETT 11771

Query: 591   KPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSK-IQKSSGIPVKPVNGRKTSL 649
                S   R  TS +F     P +T    V +T  S T+    + S+ +P +  +   T L
Sbjct: 11772 ALLSTHPRTETSKTF-----PASTVFPQVSETTASLTIRPGAETSTALPTQTTSSLFTLL 11826

Query: 650   DVSNSAEPGFLAPGARSNIQYRSLP---RPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTK 706
                 S     L+P A   +  ++ P    P   +S  +          +S++   LL T 
Sbjct: 11827 VTGTSRVD--LSPTASPGVSAKTAPLSTHPGTETSTMIP---------TSTLSLGLLETT 11875

Query: 707   QGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVAL--DSDNISLKSIGSPEST 764
                 T S  +  T   +   +PA    +       K + V       + S+ S+G PE +
Sbjct: 11876 GLLATSSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVGPPEFS 11935

Query: 765   PKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVP 824
                  +  T T +    PTP + +    V P ++     V + +L    SS        P
Sbjct: 11936 --RTVTGTTMTLIPSEMPTPPKTSHGEGVSPTTILRTTMVEATNLATTGSS--------P 11985

Query: 825   DLHATSSASGGPLPSCFTPSPAP 847
              +  T++       S FTP   P
Sbjct: 11986 TVAKTTTTFNTLAGSLFTPLTTP 12008



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 59/224 (26%), Positives = 90/224 (40%), Gaps = 28/224 (12%)

Query: 1065 SSASSTYSSAEERMQSEQIRKLRRELESSQEKVATL-TSQLSANANLVAAFEQSLVNMTS 1123
            SS+SS  S       S     L     SS   + +L TS L    +++A+      N+ S
Sbjct: 6509 SSSSSLLSLPAITSPSPVPTTLPESRPSSPVHLTSLPTSGLVKTTDMLASVASLPPNLGS 6568

Query: 1124 RLRHLAETAEE-KDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSS 1182
                +  T+E+ KDTE +     I       + ++     ++ A    PK        +S
Sbjct: 6569 TSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKV-------TS 6621

Query: 1183 DSISSLN---SITSHSSIGSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEE 1239
              ++S N   +I S S  GSS+             R      FS+  G K  S+  D   
Sbjct: 6622 PMVTSFNIRDTIVSTSMPGSSEIT-----------RIEMESTFSLAHGLKGTSTSQD--P 6668

Query: 1240 IATPDSSAPSSPKLQHGSTETASPSIKSSTSSSV-GTD-VTEGP 1281
            I + + SA    KL  G+TET+   + SS  +S+ G D  TE P
Sbjct: 6669 IVSTEKSAVLH-KLTTGATETSRTEVASSRRTSIPGPDHSTESP 6711



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 119/594 (20%), Positives = 203/594 (34%), Gaps = 95/594 (15%)

Query: 353  HYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDDITTGWDE 412
            H S  +   SP KLSH S   L    D+   +          +   T T   ++      
Sbjct: 7142 HTSPELVTSSPPKLSHTSDERLTTGKDTTNTEA---------VHPSTNTAASNVEIPSSG 7192

Query: 413  SSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDS--EKRSLAESGL 470
              S SS L+D      SE   A+S     P   T+++ ++T+ + T    E   + +  +
Sbjct: 7193 HESPSSALAD------SETSKATS-----PMFITSTQEDTTVAISTPHFLETSRIQKESI 7241

Query: 471  SWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLK 530
            S  S    +    +E  S        TS    E            E+         GS +
Sbjct: 7242 SSLSPKLRETGSSVETSSAI-----ETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAE 7296

Query: 531  KGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAK 590
                P ++ T  I     S +           +  ++ +K       S+      L D  
Sbjct: 7297 STMLPEISTTRKIIKFPTSPI---------LAESSEMTIKTQTSPPGSTSESTFTL-DTS 7346

Query: 591  KPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLD 650
              PS +   ST      ++ P +  T  V +  G      + + S +PV+  +   + L 
Sbjct: 7347 TTPSLVITHSTM----TQRLPHSEITTLVSRGAGD-----VPRPSSLPVEETSPPSSQLS 7397

Query: 651  VSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVT-----GGRGGPRPVSSSIDPSLLST 705
            +S    P  ++          +LP  + SSS SVT     G       + +S +P   S 
Sbjct: 7398 LSAMISPSPVS---------STLPASSHSSSASVTSLLTPGQVKTTEVLDASAEPETSSP 7448

Query: 706  KQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTP 765
                 T   +   ++V +      P + T      A  K     S + S  S+     T 
Sbjct: 7449 PSLSSTSVEILATSEVTTDTEKIHPFSNT------AVTKVGTSSSGHESPSSVLPDSETT 7502

Query: 766  KNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPD 825
            K  ++  T + + +   + L          P+L+N  K+ S     P+SS TT   +   
Sbjct: 7503 KATSAMGTISIMGDTSVSTL---------TPALSNTRKIQSE----PASSLTTRLRETST 7549

Query: 826  LHATSSA--SGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRM--------Y 875
               TS A  +   L    T +   +    + SFS+     +  S P+++ M         
Sbjct: 7550 SEETSLATEANTVLSKVSTGATTEVSRTEAISFSR-----TSMSGPEQSTMSQDISIGTI 7604

Query: 876  PKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPA-APTEEETEELTWSGSP 928
            P++S      ES +M ++  +    ST   T     A  P+  ET  +   G P
Sbjct: 7605 PRISASSVLTESAKMTITTQTGPSESTLESTLNLNTATTPSWVETHSIVIQGFP 7658


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 109/471 (23%), Positives = 167/471 (35%), Gaps = 60/471 (12%)

Query: 496 GTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKK-GKTPPVAVTSPITHTAQSALKVA 554
           GTS      P S   +S  GE   P     PG +   G+        P+    Q  L+++
Sbjct: 84  GTSS---RNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL---GQKGLRIS 137

Query: 555 GKP---EGKATDKGKLAVKNTGLQRSSSD----------AGRDRLSDA-----KKPPSGI 596
            +     GKAT+  K +  + G +R +S           A R R +       +  PS  
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197

Query: 597 ARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAE 656
            RP T G      P  +  +A+   T   +  ++ + S+G  ++    R  S   +  + 
Sbjct: 198 PRPPTEG------PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251

Query: 657 PGFLAPGARSNIQ---YRSLPRPAKSSSM---SVTGGRGGPRPVSSSIDPSLLSTKQGGL 710
           P    P AR   +   + S P+P    ++    VT  R    P    +  S L+T     
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSG 311

Query: 711 TPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNI--SLKSIGSPESTPKNQ 768
           T +R   P        TP P          A    +A  S +   SL+++ SP +TP +Q
Sbjct: 312 TKAR---PVPPPDNAATPLPATLPP-SPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367

Query: 769 ASHPTATKLAELPPT---------PLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTH 819
           A     T   + PP+         P   T+ S   PPS   L  + + +     +   TH
Sbjct: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH 427

Query: 820 ASKVPDLHATSSASGGPLPSCFTPSPAPILNIN-SASFSQGLE-----LMSGFSVPKETR 873
           +        T ++   P     TP  +P L    S   S  L+      +S  S P    
Sbjct: 428 SFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH 487

Query: 874 MYPKLSGL--HRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEEL 922
               LS L  H     L   +  P    SS   P+   PPA+ T    E L
Sbjct: 488 PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 75/301 (24%), Positives = 108/301 (35%), Gaps = 41/301 (13%)

Query: 631 IQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAP-GARSNIQYRSLPRPAKSSSMSVTGGRG 689
           +Q    +P  P      S  VS  + P  + P  A S++   S   P  S  M       
Sbjct: 457 LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMP------ 510

Query: 690 GPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASG--RTTPAPVNQTDREKEKAKAKAVA 747
            P    SS+ P  L T    LT   L+    +A    +T  AP+     E     A    
Sbjct: 511 -PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPC-- 567

Query: 748 LDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSN 807
                  L++  SP +TP  +     AT   + PP          +  P L  L     +
Sbjct: 568 ------PLQAPPSPLTTPPPETPSSIATPPPQAPPA---------LASPPLQGLPSPPLS 612

Query: 808 SLDLPSSSDTTHASKVPDLHATSSASGGPLPSCFTPSP----APILNINSASFSQ--GLE 861
            L  P        +  P     S  +  PL    TPSP    A  +++  A FS      
Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 672

Query: 862 LMSGFSVPKETRMYPKLSGLHRSMESL-----QMPMSLPSA---FPSSTPVPTPPAPPAA 913
           + + FS P    + P  +   ++  SL     Q+P S P++    PS+TP P  P P AA
Sbjct: 673 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 732

Query: 914 P 914
           P
Sbjct: 733 P 733



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 120/519 (23%), Positives = 179/519 (34%), Gaps = 108/519 (20%)

Query: 575  QRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKS 634
            +R  + AG    + A + P G+  P   GS    +PPP    A +   G +  + +    
Sbjct: 4    KRDKAKAGAAARTPAARAP-GLLTPRPPGS---PRPPPPVTPAALRVLGAAGAVGR---- 55

Query: 635  SGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPV 694
                 KP+  R   +  +   E    A   RS     S   PA     S   GRG   P 
Sbjct: 56   -----KPLAERAGGIGGATIPESAPRAGPTRS--AGTSSRNPASRPPAS---GRGERAPP 105

Query: 695  SSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDRE--KEKAKAKAVALDSDN 752
            + +  P  +S+      P R       ASG T P P+ Q       E+  A+  A ++  
Sbjct: 106  AKNTSPGPVSS------PGR-------ASGTTRPGPLGQKGLRISAEETVARGKATEAPK 152

Query: 753  ISLKSIGSPEST--PKNQASHPTATKLAELPPTPL---RATAKSFVKPPSLANLDKVNSN 807
             S  S G+   T  P      P   + +    T +   R    +  +PP+      V+S 
Sbjct: 153  RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS- 211

Query: 808  SLDLPSSSDTTHASKVPDLHATSSASGG-------PLPSCFTPSPAPILNINSASFS--- 857
                 S   TT  S  P      SA GG        L S  TP  +P  +  SA  +   
Sbjct: 212  ----ASEHSTTEPS--PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265

Query: 858  ---------QGLELMSGFSV-PKETRMYPKLSGLHRSM-------------------ESL 888
                     +GL+ +    V P      P L  L  S                     + 
Sbjct: 266  PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT 325

Query: 889  QMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGL 948
             +P +LP + P +TP+P  P  P+AP   +T       SP A    S      T P    
Sbjct: 326  PLPATLPPSPPLATPLPLAPPSPSAPPSLQT-----LPSPPATP-PSQAPPSMTTPPMQA 379

Query: 949  RYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSPTAATT-- 1006
               LQ+    +          +P S     L +PP+ P++LS+    T++ SPT   T  
Sbjct: 380  PPSLQTIPPIQ----------VPHSLTSPSLQAPPS-PLALSSLQATTSLGSPTLQATHS 428

Query: 1007 -----PRITRSNSIPTHEAAFELYSGSQMGSTLSLAERP 1040
                 PR T+++       A        + + LSL   P
Sbjct: 429  FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP 467



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 208/976 (21%), Positives = 295/976 (30%), Gaps = 189/976 (19%)

Query: 32  RKAAAADGRGMLPKRAKAPGGGGGMAKASAAELKVFKSGSVDSRVPGGPPASNLRKQKSL 91
           R   AA   G  P   +A G GG     SA      +S    SR P   P ++ R +++ 
Sbjct: 45  RVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERA- 103

Query: 92  TNLSFLTDSEKKLQLYEPEWSDDMAKAPKGLGKVGSKG-----REAPLMSKTLSKSEHSL 146
                      K     P  S   A      G +G KG      E     K     + S 
Sbjct: 104 --------PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSA 155

Query: 147 FQAKGSPAGGAKTPLAPLAPNLGKPSR-------IPR-GPYAEVKPLSKAPEAAVSEDGK 198
             A         TP  P +P + + SR       +PR  P A  +P ++ P  +VS   +
Sbjct: 156 LSAGARRDTSGPTPGTP-SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214

Query: 199 SDDELLSSKAKAQKSSG---PVPSAKGQEERAFLKVDPELV-VTVLGDLEQLLFSQMLDP 254
                 S  A+ + S+G     P+++     A     P     +  G            P
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274

Query: 255 ESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMTCYDSDDANPRSVSSLSNRSSPL 314
           +  +      V   R++    +  L  S +   S   T         R V    N ++PL
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGT-------KARPVPPPDNAATPL 327

Query: 315 SWRYGQSSPRLQ----AGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPMRSPSKLSHIS 370
                 S P       A  +PS   S ++  +P      +      T PM++P  L  I 
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387

Query: 371 RLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDDITTGWD--------ESSSISSGLSD 422
            +++  SL S  +      ++ S L   T      +               +S++S    
Sbjct: 388 PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447

Query: 423 ASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAPK 482
           AS    S    A  SL   P++P      S  V    S         LS  +    +AP 
Sbjct: 448 ASTPPDSPPLQAPLSL---PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPL 504

Query: 483 KLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSP 542
                  SL M P                     L+   SL  P      +TPP ++T+P
Sbjct: 505 S------SLIMPP---------------------LETQSSLAPPSL----QTPPASLTTP 533

Query: 543 ----ITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIAR 598
               +   A   L+ A  P      +         LQ   S       +   + PS IA 
Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPL----TTPPPETPSSIAT 589

Query: 599 PSTSGSFGYKKPP-------PATGTATVM-QTGGSATLSKIQKSSGIPVKPVNGRKTSLD 650
           P          PP       P +  AT   Q      L  +Q     P  P         
Sbjct: 590 PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP--------P 641

Query: 651 VSNSAEPGFLAPGARS----NIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTK 706
           +S  A P   AP A +       +   P P   +  S         P S  + PS     
Sbjct: 642 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP--------PASPPVSPSATPPS 693

Query: 707 QGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPK 766
           Q    PS    P +V        P+                            SP +TP 
Sbjct: 694 QA--PPSLAAPPLQVPPSPPASPPM----------------------------SPSATPP 723

Query: 767 NQASHPTATKLAELPPTPLRATAKSFVK------PPSLA--NLDKVNSNSLDLPSSSDTT 818
            QA  P A    ++PP+P  +   S         PP LA   L    S    LP S    
Sbjct: 724 PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK 783

Query: 819 HASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLEL-MSGFSVPKETRMYPK 877
              + P   AT      P P    P  AP        FS    L MS  + P      P 
Sbjct: 784 PPPQAPPALATPPLQALPSPPASFPGQAP--------FSPSASLPMSPLATP------PP 829

Query: 878 LSGLHRSMESLQMPMSLPSA----FPSSTPVPTP--------------PAPPAAPTEEET 919
            +    +   LQ+P S P++     P   P P P              P PP  P+   +
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 889

Query: 920 EELTWSGSPRAGQLDS 935
              T SG   AG   S
Sbjct: 890 S--TLSGPDLAGHSSS 903



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 60/290 (20%), Positives = 91/290 (31%), Gaps = 45/290 (15%)

Query: 589  AKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTS 648
            A  P S +A+P          PP     +      G A  S    S+ +P+ P+      
Sbjct: 774  ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP---SASLPMSPL------ 824

Query: 649  LDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQG 708
                  A P   AP   +    +  P P  S ++        P P +S   P L      
Sbjct: 825  ------ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878

Query: 709  GLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQ 768
            G  P   + P+   SG       +      E+ +      +       +  SP    +  
Sbjct: 879  GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG-----AAASPPPDAELA 933

Query: 769  ASHPTATKLAELPPTPLR-ATAKSFVKPPSLANLDKVNSNSLDLPSSSD---TTHASKVP 824
            A HP A      PP   R A       PP+              P S+D   T + ++ P
Sbjct: 934  ACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG------------PGSADGLCTIYETEGP 981

Query: 825  DLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRM 874
            +       S  P P    P P+P  +   A+   G    S    PK+ R+
Sbjct: 982  E-------SATPAPGALDPGPSPGTSGGKAAAGAGAGASS--RSPKQARL 1022


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 132/607 (21%), Positives = 227/607 (37%), Gaps = 75/607 (12%)

Query: 428 SSEEFNASSSLN------SLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAP 481
           + ++ NASS L+           P    + +  V +   +K S ++S  S   E E + P
Sbjct: 41  TQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGP 100

Query: 482 --KKLEYDSGSLKMEPGTSKWRRERP----ESCDDSSKGGELKKPISLGHPGSLKKGKTP 535
             KK    +  + + PG +  +        ES DD  +  + K+P+  G     K  K P
Sbjct: 101 PAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAP 160

Query: 536 PVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSD---AGRDRLSDAKKP 592
           P    S  + +  S+     + E     K K+       Q  +         ++++ K  
Sbjct: 161 PKKAKSSDSDSDSSS-----EDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAA 215

Query: 593 PSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVK----PVNGRKTS 648
            S  +  S+S S   ++   A             T+ K Q  +  PVK    P     +S
Sbjct: 216 SSSSSSSSSSSSDDSEEEKAAATP--------KKTVPKKQVVAKAPVKAATTPTRKSSSS 267

Query: 649 LDVSNSAE-----PGFLAPGARSNIQYRSLPRPAKS-SSMSVTGGRGGPRPVSSSIDPSL 702
            D S+  E     P    PG  S++   S P P KS  +          +PV SS D   
Sbjct: 268 EDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDS-- 325

Query: 703 LSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGS-P 761
            S +    +    K PTK    + T  P       K+ A++ + + DSD+       S P
Sbjct: 326 -SDESDSSSEEEKKPPTKAVVSKATTKP----PPAKKAAESSSDSSDSDSSEDDEAPSKP 380

Query: 762 ESTPKNQASHPTAT------KLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSS 815
             T KN ++ P  T      K A  P  P+    K   +    ++ ++ +S+S +    +
Sbjct: 381 AGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEE--EKT 438

Query: 816 DTTHASKVPDLHATSSASGGPLPSCFTP--SPAPILNINSASFSQGLELMSGFSVPKETR 873
               A+  P   A ++ S   LP+   P  S     + +S+S  +  E  S  +V K+ +
Sbjct: 439 KKMVATTKPKATAKAALS---LPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQ 495

Query: 874 MYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQL 933
              K++G            S P++        +  +     +EEE E+L   GSPR    
Sbjct: 496 ---KVAG--------GAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAP 544

Query: 934 DSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTI---GGLPESDDQSELPSPPALPMSLS 990
            +N    + L  +  +    S+EE +E++ +  +    G  +   Q+E       P +  
Sbjct: 545 KAN--GTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKK 602

Query: 991 AKGQLTN 997
            K Q  N
Sbjct: 603 IKLQTPN 609



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 93/433 (21%), Positives = 158/433 (36%), Gaps = 47/433 (10%)

Query: 889  QMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDR------NT 942
            Q P   P    + T  P  PA  A          + S S  +   D ++ ++       T
Sbjct: 183  QKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKT 242

Query: 943  LPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSPT 1002
            +PKK +  +   +  T   R S +      SD++ E   P      +  K    + V P 
Sbjct: 243  VPKKQVVAKAPVKAATTPTRKSSSSED-SSSDEEEEQKKP------MKNKPGPYSSVPPP 295

Query: 1003 AATTPRITRSNSIPTH----EAAFELYSGSQMGSTLSLAERPKGMIRSGSFRDPTDDVHG 1058
            +A  P+ +     P      +   E    S   S  S  E  K   ++   +  T     
Sbjct: 296  SAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPA 355

Query: 1059 SVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSL 1118
               + +SS SS   S+E+    E   K     ++S  K A  T   S      AA +Q +
Sbjct: 356  KKAAESSSDSSDSDSSED---DEAPSKPAGTTKNSSNKPAVTTK--SPAVKPAAAPKQPV 410

Query: 1119 VNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKR 1178
                  L   A+++  ++       E+    ++K  +  A  +    A        +   
Sbjct: 411  GGGQKLLTRKADSSSSEE-------ESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAP 463

Query: 1179 QNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIE 1238
            Q S DS S  +S +S      +  +  KKK +K    ++ +K  S KKG   +S+ S   
Sbjct: 464  QGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSS--- 520

Query: 1239 EIATPDSSAPSSPKLQ-HGSTETASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEE 1297
              ++ DSS     KL+  GS    +P    ++            A  A + +    +EEE
Sbjct: 521  --SSDDSSEEEEEKLKGKGSPRPQAPKANGTS------------ALTAQNGKAAKNSEEE 566

Query: 1298 EPEKKEVSELRSE 1310
            E EKK+ + + S+
Sbjct: 567  EEEKKKAAVVVSK 579



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 133/653 (20%), Positives = 214/653 (32%), Gaps = 138/653 (21%)

Query: 123 GKVGSKGREAPLMSKTLSKSEHSLFQAKGSPAGGAKTPLAPLAPNLGKPSRIPRGPYAEV 182
           G V  K ++    S +   SE    + +G PA  A  P         K   +P G     
Sbjct: 72  GPVAKKAKKKASSSDSEDSSEEEE-EVQGPPAKKAAVP--------AKRVGLPPG----- 117

Query: 183 KPLSKAPEAAVSEDGKSDDELLSSKAKAQKSSGPVPSAKGQEERAFLKVDPELVVTVLGD 242
           K  +KA E++ SE+   DD+    K K     G  P AK        K  P+   +   D
Sbjct: 118 KAAAKASESSSSEESSDDDDEEDQK-KQPVQKGVKPQAKA------AKAPPKKAKSSDSD 170

Query: 243 LEQLLFSQMLDPESQRKRTVQNVLDLRQN------LEETMSSLRGSQVTHSSLEMTCYDS 296
            +    S   +P   +K  +  V    Q                G   + SS   +   S
Sbjct: 171 SDS---SSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSS 227

Query: 297 DDANPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAP------SVGGSCRSEGTPAWYMHGE 350
           DD+     ++   ++ P      ++   ++A   P      S   S   E      M  +
Sbjct: 228 DDSEEEKAAATPKKTVPKKQVVAKAP--VKAATTPTRKSSSSEDSSSDEEEEQKKPMKNK 285

Query: 351 RAHYSHTMPMRSPSKLSH---------ISRLELVESLDSDEVDLKSGYMSDSDLMGKTMT 401
              YS   P  +P              + + + VES  S++   +S   S+ +    T  
Sbjct: 286 PGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVES--SEDSSDESDSSSEEEKKPPTKA 343

Query: 402 EDDDITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSE 461
                TT    +   +   SD+SD+ SSE+  A       PS P  + +NS       S 
Sbjct: 344 VVSKATTKPPPAKKAAESSSDSSDSDSSEDDEA-------PSKPAGTTKNS-------SN 389

Query: 462 KRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPI 521
           K ++     +    +  K P       G  K+       R+    S ++ S   E +K  
Sbjct: 390 KPAVTTKSPAVKPAAAPKQPV-----GGGQKL-----LTRKADSSSSEEESSSSEEEKTK 439

Query: 522 SLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDA 581
            +             VA T P                 KAT K  L++      + +   
Sbjct: 440 KM-------------VATTKP-----------------KATAKAALSLP----AKQAPQG 465

Query: 582 GRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKP 641
            RD  SD+    S      TS S   KKP    G A                    P KP
Sbjct: 466 SRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAA-------------------PSKP 506

Query: 642 VNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRP--AKSSSMSVTGGRGGPRPVSSSID 699
            + +K   + SNS+     +      ++ +  PRP   K++  S    + G    +S  +
Sbjct: 507 ASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEE 566

Query: 700 PSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDN 752
                 K+  +  S+        SG       N+  +E E  +AK + L + N
Sbjct: 567 EE--EKKKAAVVVSK--------SGSLKKRKQNEAAKEAETPQAKKIKLQTPN 609



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 45/233 (19%), Positives = 92/233 (39%), Gaps = 17/233 (7%)

Query: 1153 NSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKS 1212
            +SE +  +QG        P     KR       ++  +  S SS  SS D D + +KK+ 
Sbjct: 90   SSEEEEEVQGPPAKKAAVPA----KRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQP 145

Query: 1213 WLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSS 1272
              +    +A + K  PK A S SD +  ++ +   P + K +       + +      + 
Sbjct: 146  VQKGVKPQAKAAKAPPKKAKS-SDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPAR 204

Query: 1273 VGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQL 1332
                +  G A  +  +    ++ ++  E+K  +  +  + +K++ +    ++A  +    
Sbjct: 205  AAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQV-VAKAPVKAATT---- 259

Query: 1333 DQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGSSALSSPRRSLG 1385
               R++  +     D  + +   +K  PGP S   P   P       P++SLG
Sbjct: 260  -PTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAP------PPKKSLG 305



 Score = 32.3 bits (72), Expect = 4.5
 Identities = 46/176 (26%), Positives = 68/176 (38%), Gaps = 27/176 (15%)

Query: 421 SDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKA 480
           S  SD+ SSEE    +S +++   P      +       ++K     S  S   +S E+ 
Sbjct: 470 SSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEE 529

Query: 481 PKKLEYDSGSLKMEP---GTSKWRRERPESCDDSSKGGELKK--PISLGHPGSLKKGKTP 535
            +KL+         P   GTS    +  ++  +S +  E KK   + +   GSLKK K  
Sbjct: 530 EEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRK-- 587

Query: 536 PVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNT------GLQRSSSDAGRDR 585
                         A K A  P+ K   K KL   NT      G +R+SS   R R
Sbjct: 588 -----------QNEAAKEAETPQAK---KIKLQTPNTFPKRKKGEKRASSPFRRVR 629


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 183/921 (19%), Positives = 324/921 (35%), Gaps = 107/921 (11%)

Query: 434  ASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAPKK---------L 484
            ASS +NSL +TP  +    T   +  S   +   + +   + SE   P           +
Sbjct: 1527 ASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVV 1586

Query: 485  EYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPG-----SLKKGKTP---- 535
              ++ +L   P  SK +         S+        IS    G     S+    TP    
Sbjct: 1587 SSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASP 1646

Query: 536  --------PVAVTSPI----------THTAQSALKVAGKPEGKATDKGKLAVKNTGLQRS 577
                    PV   SP+          T    +++  +   EG+ T    + V+ T +  S
Sbjct: 1647 EASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGR-TPLTSITVRTTPVASS 1705

Query: 578  S----SDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQK 633
            +    S    D  +         + P+TS         P+ GT  +     S T     +
Sbjct: 1706 AISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSE 1765

Query: 634  SSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRP 693
            +S +   P++   TS  V+ S E    A  + +  +  S+P    S  M+          
Sbjct: 1766 ASTLSATPID---TSTPVTTSTE----ATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHT 1818

Query: 694  VSSSIDPSLLSTKQGGLTPSRLKEPTKVASG-RTTPAPVNQTDREKEKAKAKAVALDSDN 752
            + ++ + S LST     TP     P   ++   ++P P   T          + AL S  
Sbjct: 1819 LVANSEASTLST-----TPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIP 1873

Query: 753  ISLKSIGSPESTPKNQASHPTATKL---AELPPTPLRATAKSFVKPPSLANLDKVNSNSL 809
            +S  ++ S E+   +     T+T +   A++  +P  A   S   P S     +    S 
Sbjct: 1874 VSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSM--PTSTPREGRPPLTS- 1930

Query: 810  DLPSSSDTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVP 869
             +P S+ T  +S++  L  T + +  P+ +    S +P                 G S+P
Sbjct: 1931 -IPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSP-------------TTADGTSMP 1976

Query: 870  KETRMYPKLSGLHRSME-SLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSP 928
              T  Y + S    SM  S  + +S  ++  S+TPV T   P    TE  +   T  G+ 
Sbjct: 1977 --TPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDT-STPATTSTEGSSSPTTAGGT- 2032

Query: 929  RAGQLDSNQRDRNTLPKKGLRYQ----LQSQEETKERRHSHTIGGLPESDDQSELPSPPA 984
                + ++     T P  G+       + S+  T       +   +  S + S   +   
Sbjct: 2033 ---SIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEG 2089

Query: 985  LPMSLSAKGQ----LTNI-VSPTAATTPRITRSNSIPTHEAAFELYSGSQMGSTLSLAER 1039
              M++SA  +    LT+I +S T   +P  +  ++ P    +  + S     S +     
Sbjct: 2090 SSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGT 2149

Query: 1040 PKGMIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLR-RELESSQEKVA 1098
                      R P   +  S   +ASSA ST S+      +        R   ++ E  +
Sbjct: 2150 SMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTS 2209

Query: 1099 TLTSQLSANANLVAAFEQSLVN-MTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQ 1157
              TS  S  +    +   S +  +TS    L+ T  +  T +    E         +E  
Sbjct: 2210 MPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATS--SPTTAEGT 2267

Query: 1158 AVIQGALNASETTPKELRIKR---QNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSW- 1213
            ++    L+   T    + +      NS  S  S   + S++   +S +A +     +   
Sbjct: 2268 SIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTS 2327

Query: 1214 --LRSSFNKAFSIKKGPKSASSYSDIEE---IATP-DSSAPSSPKLQHGSTETAS--PSI 1265
                +S      + + P S +  +  E      TP D+S P +   Q GS+ T +   S+
Sbjct: 2328 MPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSM 2387

Query: 1266 KSSTSSSVGTDVTEGPAHPAP 1286
             +ST S   T +T  P    P
Sbjct: 2388 PTSTYSEGSTPLTSVPVSTMP 2408



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 191/946 (20%), Positives = 337/946 (35%), Gaps = 112/946 (11%)

Query: 380  SDEVDLKSGYMSDSDLMGKTMTEDDDITTGWDESSSISSGLSDASDNLSSEEFN----AS 435
            S E    S    DS+    T TE    +T  + +S  +S  ++ S  L+S   N    AS
Sbjct: 643  SSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVAS 702

Query: 436  SSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAP-------KKL--EY 486
            S  ++L +TP  +    T      S   +   + +   + SE   P       K L    
Sbjct: 703  SEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSS 762

Query: 487  DSGSLKMEP-GTSKWRRERPE-SCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPIT 544
            ++ +L   P  TS       E SC  ++  G    PIS    GS       P+  + P++
Sbjct: 763  EASTLSTTPLDTSTHITTSTEASCSPTTTEGT-SMPISTPSEGS-------PLLTSIPVS 814

Query: 545  HTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGS 604
             T  ++      PE          +  T +  +S       +S +  P  G + P+++ S
Sbjct: 815  ITPVTS------PEAST-------LSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYS 861

Query: 605  FGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGA 664
             G         + T++ T   +TLS           PV+   TS  V+NS E        
Sbjct: 862  EGRTPLTSMPVSTTLVATSAISTLS---------TTPVD---TSTPVTNSTEA------- 902

Query: 665  RSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPS--LLSTKQGGLTPSRLKEPTKVA 722
                  RS P  ++ +SM  +    G  P++S  D +  ++S++   L+ + +   T V 
Sbjct: 903  ------RSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVT 956

Query: 723  S---GRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPE-----STPKNQASHPTA 774
            +     ++P     T             L S  +S   + + E     +TP +  +  T 
Sbjct: 957  TSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTT 1016

Query: 775  TKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASG 834
            +  A  PP     T+     P   +        S  + +SS+T+  S  P   +T   + 
Sbjct: 1017 STEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTY 1076

Query: 835  GPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMY--PKLSGLHRSMESLQMPM 892
                S  T +     ++ ++++S+G   ++  SVP  TR+    + S L  +     +P+
Sbjct: 1077 SQASSSSTTADG--TSMPTSTYSEGSTPLT--SVPVSTRLVVSSEASTLSTTPVDTSIPV 1132

Query: 893  SLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQL 952
            +  +   SS       + P +P  E T  L          + S     +T P    + Q+
Sbjct: 1133 TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDS-KTQV 1191

Query: 953  QSQEETKERRHSHTIGGLPES---DDQSELPSPPALPMSLSAKGQLTNIVSPTAATTPRI 1009
             +  E      +  +  +P S   +  + L S P     +++    T   SP   +TP  
Sbjct: 1192 ATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVT 1251

Query: 1010 T---RSNSIPTHEAAFELYSGSQMGSTL--------SLAERPKGMIRSGSFRDPTDDVHG 1058
            T    S+S  T E      S +  GSTL        +L   P+    + +      D  G
Sbjct: 1252 TSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPE----ASTLLTTPVDTKG 1307

Query: 1059 SVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSL 1118
             V++    +SS   +    M +    + R  L S       + S   +  +       + 
Sbjct: 1308 PVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTP 1367

Query: 1119 VNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKR 1178
            V  ++       T+E       +  E    L         V+    +    TP +     
Sbjct: 1368 VTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPG 1427

Query: 1179 QNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIE 1238
              S+++ SS  +     SI +S  ++ K             K+  +   P + S  S + 
Sbjct: 1428 TTSAEATSS-PTTAEGISIPTSTPSEGKTPL----------KSIPVSNTPVANSEASTLS 1476

Query: 1239 EIATP-DSSAP--SSPKLQHGSTETASPSIKSSTSSSVGTDVTEGP 1281
               TP DS++P  +S  +    T     SI  ST S   T +T  P
Sbjct: 1477 --TTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIP 1520



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 189/974 (19%), Positives = 328/974 (33%), Gaps = 96/974 (9%)

Query: 378  LDSDEVDLKSGYMSDSDLMGKTMTEDDDITTGWDESSSISSGLSDASDNLSSEEFN---- 433
            L S E    S    D+ +   T TE     T   ++S   S  S+ S +L+S   +    
Sbjct: 2586 LASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPV 2645

Query: 434  ASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAPKKLEYDSGSLKM 493
            ASS  ++L +TP  +R   T    T S   +   S +   +  E   P      S +L  
Sbjct: 2646 ASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLA 2705

Query: 494  EPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKV 553
                S       ++    +   E     +     S++   + P   ++P+T    S L V
Sbjct: 2706 NSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMR--ISTPSDGSTPLTSILVSTLPV 2763

Query: 554  AGKPEGKATDKGKLAVK-----NTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYK 608
            A     +A+     AV       T  + SSS    +  S     PS  + P TS    + 
Sbjct: 2764 A---SSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNH- 2819

Query: 609  KPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAE--------PGFL 660
              P A+  A  + T    T + +  S+     P       + +S ++E        P   
Sbjct: 2820 -TPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVST 2878

Query: 661  APGARS------------------NIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSL 702
             P A S                  + +  S P  A+ +SM ++     P  VS+ +   L
Sbjct: 2879 TPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPIS----TPSEVSTPLTSIL 2934

Query: 703  LST--------KQGGLTPSRLKEP-TKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNI 753
            +ST             TP   + P T  A   ++P     T         +   L S ++
Sbjct: 2935 VSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSV 2994

Query: 754  SLKSIGSPES-----TPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNS 808
            S   + S E+     TP + ++  T +  A   PT    T      P       + ++  
Sbjct: 2995 STMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTP------SEGSTPL 3048

Query: 809  LDLPSSSDTTHASKVPDLHATSSASGGPLPS----CFTPSPAPILNINSASFSQGLELMS 864
              +P S+      +   L  T   S  P+ +      +P+PA   ++  +++S+G   ++
Sbjct: 3049 TSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLT 3108

Query: 865  GFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTW 924
            G  V         +S L  +      P++  +   SS       + P +   E +  LT+
Sbjct: 3109 GVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTY 3168

Query: 925  SGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHT-IGGLPESDDQSELPSPP 983
                    + S     +  P         S E T       T I     S+  + L S P
Sbjct: 3169 MPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVP 3228

Query: 984  ALPMSLSAKGQLTNIVSPTAATTPRIT---RSNSIPTHEAAFELYSGSQMGSTLSLAERP 1040
                 +++        +P  + TP  T    S+S PT E      S    GST  L   P
Sbjct: 3229 VSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGST-PLTSMP 3287

Query: 1041 KGMIRSGSFRDPT-----DDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQE 1095
                   S    T      D    V + + ++SS   +    M +    +    L +   
Sbjct: 3288 VSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSF 3347

Query: 1096 KVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSE 1155
                + S  ++  +       + V  ++       TAE          E    L      
Sbjct: 3348 STTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVS 3407

Query: 1156 AQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLR 1215
               V+   +N   TTP +       S+++ SS  +I   +S+ +S  ++           
Sbjct: 3408 TTPVVSSEVNTLSTTPVDSNTLVTTSTEA-SSSPTIAEGTSLPTSTTSEG---------- 3456

Query: 1216 SSFNKAFSIKKGPKSASSYSDIEEIATP-DSSAPSSPKLQHGSTETAS--PSIKSSTSSS 1272
            S+      +   P ++S  S +    TP D+S P +      S+ T +   S+ +ST+  
Sbjct: 3457 STPLSIMPLSTTPVASSEASTLS--TTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGE 3514

Query: 1273 VGTDVTEGPAHPAP 1286
              T +T  P    P
Sbjct: 3515 GSTPLTNMPVSTTP 3528



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 166/783 (21%), Positives = 274/783 (34%), Gaps = 113/783 (14%)

Query: 371  RLELVESLDSDEVDLKSGYMSDSDLMGKT-MTEDDDITTGWDESSSISSGLSDASDNLSS 429
            R+ L  S + +   ++S   SD+  +  T MT  +  TT   ES+S S+ L         
Sbjct: 80   RMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTS--ESTSDSTTL--------- 128

Query: 430  EEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAPKKLEYDSG 489
              F +S+   S P+TP      + + + T SE+     S +++ S +    P    Y S 
Sbjct: 129  --FPSSTEDTSSPTTP----EGTDVPMSTPSEES--ISSTMAFVSTAP--LPSFEAYTSL 178

Query: 490  SLKMEPGTSKWRRER-------PESCD-DSSKGGELKKPISLGHPGSLKKGK-------T 534
            + K++  T      +       PES     S   E   P++     ++K          T
Sbjct: 179  TYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLT 238

Query: 535  PPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQR---SSSDAGRDRLSDAKK 591
             PV +++P+T +AQ++       EG +      +  +T L R   S         S    
Sbjct: 239  TPVEISTPVTISAQASSSPT-TAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLST 297

Query: 592  PPSGIARPSTSGSFGYKKPPPATGTA--TVMQTGGSATLSKIQKS---------SGIPVK 640
             P+    P  + +     P  A GT+  T   T GS  L+    S         S + + 
Sbjct: 298  TPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSIT 357

Query: 641  PVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDP 700
            PV+   TS  V+ S EP              SLP  A+++SM  +    G  P+++    
Sbjct: 358  PVD---TSTLVTTSTEPS-------------SLPTTAEATSMLTSTLSEGSTPLTNMPVS 401

Query: 701  SLLSTKQGGLTPSRLKEPTK-----VASGRTTPAPVNQTDREKEKAKAKAVALDSDNISL 755
            ++L       T S +   +K      +   ++P     T          +  L S  +S 
Sbjct: 402  TILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVST 461

Query: 756  KSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSS 815
              + S E++  N ++ P  +K      T +  + ++   PP+     +VNS     PS  
Sbjct: 462  TPVASSEAS--NLSTTPVDSK------TQVTTSTEASSSPPTA----EVNSMPTSTPSEG 509

Query: 816  DTTHASKVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMY 875
             T   S        +S+    L +    +  P+   + AS S       G S+P  T   
Sbjct: 510  STPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSS--TTPEGTSIPTSTPS- 566

Query: 876  PKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDS 935
                    S     MP+S      SS    T   P  + T   T     S S  A   + 
Sbjct: 567  ------EGSTPLTNMPVS-TRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTA---EG 616

Query: 936  NQRDRNTLPKKGLRYQLQSQEET-KERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQ 994
                 +T  ++G      S   T      + T+   P   +     S  A   S +A+G 
Sbjct: 617  TSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEG- 675

Query: 995  LTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSGSFRDPTD 1054
                  PT+  T   T   S+P +         S + +T      P       S    T 
Sbjct: 676  ---TSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTA 732

Query: 1055 DVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAF 1114
            D        AS  +ST S     + S  + K    L +S E     T+ L  + ++  + 
Sbjct: 733  DG-------ASMPTSTPSEGSTPLTSMPVSK---TLLTSSEASTLSTTPLDTSTHITTST 782

Query: 1115 EQS 1117
            E S
Sbjct: 783  EAS 785



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 193/918 (21%), Positives = 327/918 (35%), Gaps = 137/918 (14%)

Query: 407  TTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLA 466
            TT  D S+ +++     S   +SE  +  +S  S  STP      ST+++   SE  +L+
Sbjct: 3127 TTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLV-VSSEDSTLS 3185

Query: 467  ESGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHP 526
             + +      +   P     ++ S     GTS       E     +       P++    
Sbjct: 3186 ATPV------DTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEA 3239

Query: 527  GSLKKGKTPPVAVTSPITHT--AQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRD 584
              L    T PV   +P+T +  A S+   A       +   + +   T +  S++     
Sbjct: 3240 SILS---TTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASS 3296

Query: 585  RLSDAKKPPSGIARPSTSGSFGYKKPPPATGTA--TVMQTGGSATLSKI---------QK 633
              S     P+  + P T+ S     PP A GT+  T   + GS  L+ +          +
Sbjct: 3297 ETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSE 3356

Query: 634  SSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRP 693
            +S +   PV+   TS  V+ S E                       +S+S T   G   P
Sbjct: 3357 ASTLSTTPVD---TSTPVTTSTE-----------------------ASLSPTTAEGTSIP 3390

Query: 694  VSS-SIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDN 752
             SS S   + L++     TP    E   ++   TTP   N             V   ++ 
Sbjct: 3391 TSSPSEGTTPLASMPVSTTPVVSSEVNTLS---TTPVDSN-----------TLVTTSTEA 3436

Query: 753  ISLKSIGSPESTPKNQASH-PTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDL 811
             S  +I    S P +  S   T   +  L  TP+ ++  S +    +     V ++S   
Sbjct: 3437 SSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSS-PT 3495

Query: 812  PSSSDTTHASKVPDLHATSSASGGPLPSCFTP-SPAPILNINSASFSQGLELMSGFSVPK 870
             SS  T   + +P    TS+A  G  P    P S  P+ +  +++ S         + P 
Sbjct: 3496 NSSPTTAEVTSMP----TSTAGEGSTPLTNMPVSTTPVASSEASTLS---------TTPV 3542

Query: 871  ETRMY----PKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSG 926
            ++  +     + S    +++   M MS PS   SS       +     +E  T   T S 
Sbjct: 3543 DSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPS-TPSV 3601

Query: 927  SPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKE----RRHSHTIGGLPESDDQSELPSP 982
                    S Q +    P + +   + +  E          S T   + E+   S LP  
Sbjct: 3602 DRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVD 3661

Query: 983  PALPMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMGSTLSLAERPKG 1042
             + P+  S +   ++ V+P   T P  T S                  GST  L   P  
Sbjct: 3662 TSTPVITSTQVS-SSPVTPEGTTMPIWTPSE-----------------GST-PLTTMPVS 3702

Query: 1043 MIRSGSFRDPTDDVHGSVLSLASSASST-YSSAEERMQSEQIRKLRRELESSQEKVATLT 1101
              R  S         GS LS  S  +ST  +++ E + S           S   +++TL 
Sbjct: 3703 TTRVTS-------SEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLG 3755

Query: 1102 SQLSANANLVAAF-EQSLVNMTSRLRHLA-ETAEEKDTELLDLRETIDFLKKKNSEAQAV 1159
            + +  +   V  F E S  ++ S    ++  TA E  +    L  T        SE   +
Sbjct: 3756 TTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTL 3815

Query: 1160 IQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLRSSFN 1219
            +   L +       + +   + + ++S+    TS   + S+K        + + +R S  
Sbjct: 3816 LTTVLIS------PISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISIT 3869

Query: 1220 KAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHG-----STETAS-PSIKSSTSSSV 1273
               S +  P +    S     + P +S  S+P L        ST+TAS P+I  +T+ SV
Sbjct: 3870 ---SERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISV 3926

Query: 1274 GTDVTEGPAHPAPHTRLF 1291
               +TEG     P T +F
Sbjct: 3927 SV-ITEG---STPGTTIF 3940



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 49/257 (19%), Positives = 91/257 (35%), Gaps = 12/257 (4%)

Query: 612  PATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFL-----APGARS 666
            P    A+      S T +    ++  P  PV    +   ++  + PG        P   S
Sbjct: 3890 PGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSS 3949

Query: 667  NIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRT 726
                      A S+ +  +     P   SSS   S  +TK+          P    +  T
Sbjct: 3950 TADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMST 4009

Query: 727  TPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLR 786
             P+    T R    + +   A  + + S  S+ +   TP +++S P+      +PPT   
Sbjct: 4010 APSTPRTTSRGCTTSASTLSATSTPHTST-SVTTRPVTPSSESSRPSTITSHTIPPT--F 4066

Query: 787  ATAKSFVKPPSLANLDKVNSNSLDLPS--SSDTTHASKVPDLHATSSASGGPLPSCFTPS 844
              A S   P + A+   VN  ++   +  +  +T  +  P +  T+  +   + S   P+
Sbjct: 4067 PPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKS--NPT 4124

Query: 845  PAPILNINSASFSQGLE 861
              P +   +  F  G +
Sbjct: 4125 STPTVPRTTTCFGDGCQ 4141



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 27/119 (22%), Positives = 48/119 (40%)

Query: 1164 LNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLRSSFNKAFS 1223
            ++++  TP E R   +++SDS +   S T  +S  ++ +         S    S   AF 
Sbjct: 105  VSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFV 164

Query: 1224 IKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGTDVTEGPA 1282
                  S  +Y+ +       +   +S +     T   S +I  ST+S   T +T  PA
Sbjct: 165  STAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPA 223


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 97/434 (22%), Positives = 161/434 (37%), Gaps = 55/434 (12%)

Query: 600  STSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGF 659
            ST G+      P  T T TV  TG +AT S  Q ++G P   V+   T+  V++S    F
Sbjct: 3717 STPGTTWILTEPSTTATVTV-PTGSTATASSTQATAGTP--HVSTTATTPTVTSSKATPF 3773

Query: 660  LAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPT 719
             +PG  + +       PA  S+ +         P ++S   + + +   G T +RL + T
Sbjct: 3774 SSPGTATAL-------PALRSTATT--------PTATSF--TAIPSSSLGTTWTRLSQTT 3816

Query: 720  KVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTP--KNQASHPTATKL 777
               +  +T  P +  +           A  +   +  S+ +P STP   +    PT T  
Sbjct: 3817 TPTATMSTATPSSTPETAHTSTVLTTTA--TTTRATGSVATPSSTPGTAHTTKVPTTTTT 3874

Query: 778  A-ELPPTPLRATAKSFVKPP---SLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSAS 833
               + P+    TA++   PP   S       + +++   S   TTH   V     T+ A+
Sbjct: 3875 GFTVTPSSSPGTART---PPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVAT 3931

Query: 834  GG---PLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQM 890
            G    P  S  T    P L   + + +      +  S P  T + P L+    +  +   
Sbjct: 3932 GSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSS 3991

Query: 891  PMSLPSAFPSSTPVPTPPAP---------PAAPTEEETEELTWSGSPRAGQLDSNQRDRN 941
             ++  SA  ++    TPP P           +P+   T    W+ S  +G L +      
Sbjct: 3992 TVTPSSALGTT---HTPPVPNTTATTHGRSLSPSSPHTVRTAWT-SATSGTLGTT---HI 4044

Query: 942  TLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSP 1001
            T P  G  +   +   T +          P S      PSP       +  G  T     
Sbjct: 4045 TEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSP-----GTTTPGHTTATSRT 4099

Query: 1002 TAATTPRITRSNSI 1015
            TA  TP  TR++++
Sbjct: 4100 TATATPSKTRTSTL 4113



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 93/431 (21%), Positives = 155/431 (35%), Gaps = 49/431 (11%)

Query: 600  STSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGF 659
            ST G+      P  T T TV  TG +AT S  Q ++G P   V+   T+  V++S    F
Sbjct: 2460 STPGTTWILTEPSTTATVTV-PTGSTATASSTQATAGTP--HVSTTATTPTVTSSKATPF 2516

Query: 660  LAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPT 719
             +PG  + +       PA  S+ +         P ++S   + + +   G T +RL + T
Sbjct: 2517 SSPGTATAL-------PALRSTATT--------PTATSF--TAIPSSSLGTTWTRLSQTT 2559

Query: 720  KVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASH---PTATK 776
               +  +T  P +  +           A  +   +  S+ +P STP    +     T T 
Sbjct: 2560 TPTATMSTATPSSTPETVHTSTVLTTTATTTG--ATGSVATPSSTPGTAHTTKVLTTTTT 2617

Query: 777  LAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGG- 835
                 P+    TA++     S         +++   S   TTH   V     T+ A+G  
Sbjct: 2618 GFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSM 2677

Query: 836  --PLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMS 893
              P  S  T    P L   + + +      +  S P  T + P L+    +  +    ++
Sbjct: 2678 ATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVT 2737

Query: 894  LPSAFPSSTPVPTPPAP---------PAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLP 944
              SA  ++    TPP P           +P+   T    W+ S  +G L +      T P
Sbjct: 2738 PSSALGTT---HTPPVPNTTATTHGRSLSPSSPHTVRTAWT-SATSGTLGTT---HITEP 2790

Query: 945  KKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSPTAA 1004
              G  +   +   T +          P S      PSP       +  G        TA 
Sbjct: 2791 STGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSP-----GTTTPGHTRATSRTTAT 2845

Query: 1005 TTPRITRSNSI 1015
             TP  TR++++
Sbjct: 2846 ATPSKTRTSTL 2856



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 92/438 (21%), Positives = 159/438 (36%), Gaps = 49/438 (11%)

Query: 594  SGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSN 653
            S  A PS++    +    P T   T   TG +AT +   +++  P K +    T+  V++
Sbjct: 1895 SSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAP-PPKVLTTTATTPTVTS 1953

Query: 654  SAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPS 713
            S      +PG  + +       PA  S+ +         P ++S+ P  + +   G T +
Sbjct: 1954 SKATPSSSPGTATAL-------PALRSTATT--------PTATSVTP--IPSSSLGTTWT 1996

Query: 714  RLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTP--KNQASH 771
            RL + T   +  +T  P +  +         A A  +   +  S+ +P STP   +    
Sbjct: 1997 RLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTG--ATGSVATPSSTPGTAHTTKV 2054

Query: 772  PTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSS--DTTHASKVPDLHAT 829
            PT T       TP  +   +   P  ++      +    +  SS   TTH + V     T
Sbjct: 2055 PTTTTTG-FTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT 2113

Query: 830  SSASGG---PLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSME 886
            + A+G    P  S  T    P L   + + +      +  S P  T + P L+    +  
Sbjct: 2114 TVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPA 2173

Query: 887  SLQMPMSLPSAFPSSTPVPTP---------PAPPAAPTEEETEELTWSGSPRAGQLDSNQ 937
            +    ++  SA  ++   P P           PP++P    T    W+ S  +G L +  
Sbjct: 2174 ATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSP---HTVRTAWT-SATSGILGTT- 2228

Query: 938  RDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTN 997
                T P     + L +   T +          P S      PSP       +  G  T 
Sbjct: 2229 --HITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSP-----GTTTPGHTTA 2281

Query: 998  IVSPTAATTPRITRSNSI 1015
                TA  TP  TR++++
Sbjct: 2282 TSRTTATATPSKTRTSTL 2299



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 85/397 (21%), Positives = 134/397 (33%), Gaps = 52/397 (13%)

Query: 534  TPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPP 593
            T P  ++S  T ++      A  P  ++T     A   T +  SS      RLS    P 
Sbjct: 3204 TTPTVISSRATPSSSPGTATA-LPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPT 3262

Query: 594  SGI--ARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDV 651
            + +  A PS++    +      T T T   TG  AT S    ++     P     T    
Sbjct: 3263 ATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTT-TTTGFTA 3321

Query: 652  SNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLT 711
            + S+ PG             +L  P   S+ +    RG      S++ PS +       T
Sbjct: 3322 TPSSSPG------------TALTPPVWISTTTTPTTRG------STVTPSSIPGTTHTAT 3363

Query: 712  PSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASH 771
                   T       TP+   QT          A  + +      S  +P STP      
Sbjct: 3364 VLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATG----STTNPSSTPGTTPIP 3419

Query: 772  PTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLH---- 827
            P  T  A  P     A   S V P S        +++  +P+++ TTH   +P       
Sbjct: 3420 PVLTTTATTP-----AATSSTVTPSSALG----TTHTPPVPNTTATTHGRSLPPSSPHTV 3470

Query: 828  --ATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSM 885
              A +SA+ G L +     P+ + +   A+ +   +              P LS  H S 
Sbjct: 3471 RTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQ-----------HSTPALSSPHPSS 3519

Query: 886  ESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEEL 922
             + + P S  +  P  T   +     A P++  T  L
Sbjct: 3520 RTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTL 3556



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 94/445 (21%), Positives = 144/445 (32%), Gaps = 66/445 (14%)

Query: 495  PGTSKWRRERPES-CDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKV 553
            PGT+ W   +P +    ++  G    P S     +L+    P V  T+  T T  S+   
Sbjct: 1904 PGTT-WILTKPTTTATTTASTGSTATPTS-----TLRTAPPPKVLTTTATTPTVTSSKAT 1957

Query: 554  AGKPEGKATDKGKL--------AVKNTGLQRSSSDAGRDRLSDAKKPPSGI--ARPSTSG 603
                 G AT    L        A   T +  SS      RLS    P + +  A PS++ 
Sbjct: 1958 PSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTP 2017

Query: 604  SFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPG 663
               +      T TAT     GS         +    K      T    + S+ PG     
Sbjct: 2018 ETAHTSTV-LTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPG----- 2071

Query: 664  ARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVAS 723
                    +L  P   S+ +    RG      S++ PS +       T       T    
Sbjct: 2072 -------TALTPPVWISTTTTPTTRG------STVTPSSIPGTTHTATVLTTTTTTVATG 2118

Query: 724  GRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPT 783
               TP+   QT          A  + +      S  +P STP      P  T  A  P  
Sbjct: 2119 SMATPSSSTQTSGTPPSLTTTATTITATG----STTNPSSTPGTTPIPPVLTTTATTP-- 2172

Query: 784  PLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLH------ATSSASGGPL 837
               A   + V P S        +++  +P++  TTH   +P         A +SA+ G L
Sbjct: 2173 ---AATSNTVTPSSALG----TTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGIL 2225

Query: 838  PSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSA 897
             +     P+ + +   A+           +        P LS  H S  + + P S  + 
Sbjct: 2226 GTTHITEPSTVTSHTLAA-----------TTGTTQHSTPALSSPHPSSRTTESPPSPGTT 2274

Query: 898  FPSSTPVPTPPAPPAAPTEEETEEL 922
             P  T   +     A P++  T  L
Sbjct: 2275 TPGHTTATSRTTATATPSKTRTSTL 2299



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 106/475 (22%), Positives = 170/475 (35%), Gaps = 71/475 (14%)

Query: 600  STSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGF 659
            ST G+      P  T T TV  TG +AT S  Q ++G P   V+   T+  V++S     
Sbjct: 4445 STPGTTWILTEPSTTATVTV-PTGSTATASSTQATAGTP--HVSTTATTPTVTSSKATPS 4501

Query: 660  LAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPT 719
             +PG  + +       PA  S+ +         P ++S   + + +   G T +RL + T
Sbjct: 4502 SSPGTATAL-------PALRSTATT--------PTATSF--TAIPSSSLGTTWTRLSQTT 4544

Query: 720  KVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTP--KNQASHPTATKL 777
               +  +T  P +  +         A A  +   +  S+ +P STP   +    PT T  
Sbjct: 4545 TPTATMSTATPSSTPETVHTSTVLTATATTTG--ATGSVATPSSTPGTAHTTKVPTTTTT 4602

Query: 778  AELPPTPLRATAKSFVKPPSLA------NLDKVNSNSLDLPSS-SDTTHASKVPDLHATS 830
                 TP  +   +   P  ++            S S   PSS   TTH ++V     T+
Sbjct: 4603 G-FTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTT 4661

Query: 831  SASGG---PLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMES 887
             A+G    P  S  T    P L   + + +      +  S P  T + P L+    +  +
Sbjct: 4662 VATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAA 4721

Query: 888  LQMPMSLPSAFPSSTPVPT-------PPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDR 940
                 +  S+  ++T +P          A    P    T   TW+   +     S     
Sbjct: 4722 TSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTI 4781

Query: 941  NTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPALPMSLSAK----GQLT 996
            +T               T E  H+ T+  L  +   +   +  A P S         +LT
Sbjct: 4782 HT-------------SSTPETTHTSTV--LTTTATMTRATNSTATPSSTLGTTRILTELT 4826

Query: 997  NIVSPTAAT--------TPRITRSNSIPTHEAAFELYSGS--QMGSTLSLAERPK 1041
               + TAAT        TP  T   + P+  A   + +GS     STL  A  PK
Sbjct: 4827 TTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPK 4881



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 109/518 (21%), Positives = 183/518 (35%), Gaps = 61/518 (11%)

Query: 522  SLGHPGSLKKGKTPPVAVTSPI--------THTAQSALKVAGKPEGKATDKGKLAVKNTG 573
            +LG  G+L +  T P+A  S I        THT  S +        +AT          G
Sbjct: 3076 TLGTTGTLPEQTTTPMATMSTIHPSSTPETTHT--STVLTTKATTTRATSSMSTPSSTPG 3133

Query: 574  LQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQK 633
                 ++      + A   P+     ST G+      P  T T TV  TG +AT S  + 
Sbjct: 3134 TTWILTELTTAATTTAATGPTATPS-STPGTTWILTEPSTTATVTV-PTGSTATASSTRA 3191

Query: 634  SSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRP 693
            ++G  +K +    T+  V +S      +PG  + +       PA  S+ +         P
Sbjct: 3192 TAG-TLKVLTSTATTPTVISSRATPSSSPGTATAL-------PALRSTATT--------P 3235

Query: 694  VSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNI 753
             ++S+  + + +   G   +RL + T   +  +T  P   +  E            +   
Sbjct: 3236 TATSV--TAIPSSSLGTAWTRLSQTTTPTATMSTATP--SSTPETVHTSTVLTTTTTTTR 3291

Query: 754  SLKSIGSPESTP--KNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDL 811
            +  S+ +P STP   +    PT T       TP  +   +   P  ++      +    +
Sbjct: 3292 ATGSVATPSSTPGTAHTTKVPTTTTTG-FTATPSSSPGTALTPPVWISTTTTPTTRGSTV 3350

Query: 812  PSSS--DTTHASKVPDLHATSSASGG---PLPSCFTPSPAPILNINSASFSQGLELMSGF 866
              SS   TTH + V     T+ A+G    P  S  T    P L   + + +      +  
Sbjct: 3351 TPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPS 3410

Query: 867  SVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPS--STPVPTPPA-------PPAAPTEE 917
            S P  T + P L+    +  +    ++  SA  +  + PVP   A       PP++P   
Sbjct: 3411 STPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSP--- 3467

Query: 918  ETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQS 977
             T    W+ S  +G L +      T P     +   +   T +          P S    
Sbjct: 3468 HTVRTAWT-SATSGILGTT---HITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTE 3523

Query: 978  ELPSPPALPMSLSAKGQLTNIVSPTAATTPRITRSNSI 1015
              PSP       +  G        TA  TP  TR++++
Sbjct: 3524 SPPSP-----GTTTPGHTRGTSRTTATATPSKTRTSTL 3556



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 156/818 (19%), Positives = 265/818 (32%), Gaps = 117/818 (14%)

Query: 534  TPPVAVTSPITHTAQSALKVAGKPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPP 593
            TPPV +++  T T + +        G       L    T +   S               
Sbjct: 2075 TPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGS--------------- 2119

Query: 594  SGIARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSN 653
              +A PS+S       P   T   T+  TG +   S    ++ IP        T    SN
Sbjct: 2120 --MATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSN 2177

Query: 654  SAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPS 713
            +  P        +         P   ++M+ T GR  P     ++  +  S   G L  +
Sbjct: 2178 TVTPSSALGTTHT---------PPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTT 2228

Query: 714  RLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPT 773
             + EP+ V S  T  A    T            AL S + S ++  SP S       H T
Sbjct: 2229 HITEPSTVTS-HTLAATTGTTQH-------STPALSSPHPSSRTTESPPSPGTTTPGHTT 2280

Query: 774  ATKLAELPPTPLRA-TAKSFVKPPSLANLDKVNSNSLDLPSS----SDTTHASKVP---- 824
            AT       TP +  T+      P+ A +  V +   +   +     D ++    P    
Sbjct: 2281 ATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGD 2340

Query: 825  -DLHATSSASGGPLPSCFTP---------SPAPIL----NINSASFSQGLELMSGFSVPK 870
             D ++   A+GG +  C  P          P   L     +   S   GL   +   V K
Sbjct: 2341 FDTYSNIRAAGGAV--CEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGK 2398

Query: 871  -------ETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELT 923
                   E R++    G H          ++PS+ P +T + T     A  TE      T
Sbjct: 2399 FKMCFNYEIRVFCCNYG-HCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTAT 2457

Query: 924  WSGSPRAGQLDSNQRDRNTLP-KKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELP-S 981
             S +P    + +      T+    G      S + T    H  T    P        P S
Sbjct: 2458 PSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFS 2517

Query: 982  PPALPMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMGST---LSLAE 1038
             P    +L A          + ATTP  T   +IP+          S +G+T   LS   
Sbjct: 2518 SPGTATALPA--------LRSTATTPTATSFTAIPS----------SSLGTTWTRLSQTT 2559

Query: 1039 RPKGMIRSGSFRDPTDDVHGS-VLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKV 1097
             P   + + +     + VH S VL+  ++ +    S      +       + L ++    
Sbjct: 2560 TPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGF 2619

Query: 1098 ATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETA----EEKDTELLDLRETIDFLKKKN 1153
                S     A  +  +  +    T+R   +  ++        T L     T+       
Sbjct: 2620 TATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMAT 2679

Query: 1154 SEAQAVIQGALNASETTPKELRIKRQNSSDS-------------------ISSLNSITSH 1194
              +     G   +  TT   +      ++ S                    ++ +++T  
Sbjct: 2680 PSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPS 2739

Query: 1195 SSIGSSKDADAKKKKKKSWLRS-SFNKAFSIKKGPKSASSYS-DIEEIATPDSSAPSSPK 1252
            S++G++           +  RS S +   +++    SA+S +     I  P +    +P 
Sbjct: 2740 SALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPA 2799

Query: 1253 LQHGSTETASPSIKSSTSSSVGTDVTEGPAHPAP-HTR 1289
               G+T+ ++P++ S   SS  T+    P    P HTR
Sbjct: 2800 ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTR 2837



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 69/301 (22%), Positives = 101/301 (33%), Gaps = 50/301 (16%)

Query: 534  TPPVAVTSPITHTAQSALKVAGKPEGKATDKGKL------AVKNTGLQRSSSDAGRDRLS 587
            TP  A TS +  T  +  +  G     ++  G            TG   + S +      
Sbjct: 3830 TPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSP----G 3885

Query: 588  DAKKPPSGIAR---PSTSGSFGYKKPPPATG--------TATVMQTGGSATLSKIQKSSG 636
             A+ PP  I+    P+TSGS       P T         T T + TG  AT S   ++SG
Sbjct: 3886 TARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSG 3945

Query: 637  IPVKPVNGRKTSLDVSNSAEPGFL---------------APGARSNIQYRSLP-----RP 676
             P   +    T     ++  P                   P A S+    S        P
Sbjct: 3946 TPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTP 4005

Query: 677  AKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDR 736
               ++ + T GR        ++  +  S   G L  + + EP+   S   TPA    T +
Sbjct: 4006 PVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSH--TPAATTGTTQ 4063

Query: 737  EKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPP 796
                A      L S + S ++  SP S       H TAT       TP + T  S + P 
Sbjct: 4064 HSTPA------LSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSK-TRTSTLLPS 4116

Query: 797  S 797
            S
Sbjct: 4117 S 4117



 Score = 34.7 bits (78), Expect = 0.90
 Identities = 69/334 (20%), Positives = 123/334 (36%), Gaps = 19/334 (5%)

Query: 979  LPSPPALPMSLSAKGQLTNIVSPTAATTPRITRSNSIPTHEAAFELYSGSQMGSTLSLAE 1038
            L SP   P + S+K   T+  SP  ATT  +  S +  +   +      S +G+T +L E
Sbjct: 4285 LTSPATTPTATSSKA--TSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPE 4342

Query: 1039 RPKGMIRSGSFRDPT---DDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQE 1095
            +    + + S   P+   +  H S + L + A++T +++     S          E +  
Sbjct: 4343 QTTTPVATMSTIHPSSTPETTHTSTV-LTTKATTTRATSSTSTPSSTPGTTWILTELTTA 4401

Query: 1096 KVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSE 1155
               T  +  +A  +        L  +T+     A T             T   L + ++ 
Sbjct: 4402 ATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPS--STPGTTWILTEPSTT 4459

Query: 1156 AQAVI----QGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKK 1211
            A   +        ++++ T     +    ++ +++S +  T  SS G++    A +    
Sbjct: 4460 ATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTS-SKATPSSSPGTATALPALRSTAT 4518

Query: 1212 SWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSS-PKLQHGSTE-TASPSIKSST 1269
            +   +SF    S   G             AT  ++ PSS P+  H ST  TA+ +   +T
Sbjct: 4519 TPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGAT 4578

Query: 1270 SSSVGTDVTEGPAH----PAPHTRLFHANEEEEP 1299
             S      T G AH    P   T  F A     P
Sbjct: 4579 GSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSP 4612



 Score = 34.7 bits (78), Expect = 0.90
 Identities = 70/329 (21%), Positives = 108/329 (32%), Gaps = 22/329 (6%)

Query: 597  ARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAE 656
            A PS+S       PP    T T   T    T       S IP      R  +   +  A 
Sbjct: 4606 ATPSSSPGTALT-PPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVAT 4664

Query: 657  PGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPR--PVSSSIDPSLLSTKQGGLTPSR 714
                 P + +            +++++ TG    P   P ++ I P L ST     TP+ 
Sbjct: 4665 GSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTST---ATTPAA 4721

Query: 715  LK-EPTKVASGRT-TPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQAS-- 770
               + T  +S RT T  PV  +   K  A +      S   +  ++ +  +TP +  S  
Sbjct: 4722 TSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTI 4781

Query: 771  HPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATS 830
            H ++T       T L  TA       S A        +  L   + T   +      AT 
Sbjct: 4782 HTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATL 4841

Query: 831  SASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQM 890
            S++ G       PS    + + + S +     +     PK                   M
Sbjct: 4842 SSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMAT------------M 4889

Query: 891  PMSLPSAFPSSTPVPTPPAPPAAPTEEET 919
            P +  S  PSS+ V T   P   P+   T
Sbjct: 4890 PTATASTVPSSSTVGTTRTPAVLPSSLPT 4918



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 44/210 (20%), Positives = 77/210 (36%), Gaps = 22/210 (10%)

Query: 711  TPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPK---N 767
            TPS     T + + +TT A    T        +         +   +  +P +T     +
Sbjct: 2985 TPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATS 3044

Query: 768  QASHPTATKLAELPPTPLRATAKSFVKPPS--LANLDKVNSNSLDLPSSSDTTHASKVPD 825
             +S  TAT L  L  T  ++TA SF   PS  L     +   +    ++  T H S  P+
Sbjct: 3045 SSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPE 3104

Query: 826  LHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSM 885
               TS+                +L   + +      + +  S P  T +  +L+    + 
Sbjct: 3105 TTHTST----------------VLTTKATTTRATSSMSTPSSTPGTTWILTELT-TAATT 3147

Query: 886  ESLQMPMSLPSAFPSSTPVPTPPAPPAAPT 915
             +   P + PS+ P +T + T P+  A  T
Sbjct: 3148 TAATGPTATPSSTPGTTWILTEPSTTATVT 3177



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 46/202 (22%), Positives = 74/202 (36%), Gaps = 18/202 (8%)

Query: 596  IARPSTSGSFGYKKPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSA 655
            +A PS+S       P   T   T+  TG +   S    ++  P+ PV    T+   + +A
Sbjct: 2677 MATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTT--PIPPV---LTTTATTPAA 2731

Query: 656  EPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRL 715
                + P +     +     P   ++ + T GR        ++  +  S   G L  + +
Sbjct: 2732 TSSTVTPSSALGTTH----TPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 2787

Query: 716  KEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTAT 775
             EP+   S   TPA    T +          AL S + S ++  SP S       H  AT
Sbjct: 2788 TEPSTGTS--HTPAATTGTTQH------STPALSSPHPSSRTTESPPSPGTTTPGHTRAT 2839

Query: 776  KLAELPPTPLRATAKSFVKPPS 797
                   TP + T  S + P S
Sbjct: 2840 SRTTATATPSK-TRTSTLLPSS 2860


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 221/998 (22%), Positives = 337/998 (33%), Gaps = 107/998 (10%)

Query: 350  ERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDDITTG 409
            E +  SH+ P    + +        V   DS    + SG M  + L G T         G
Sbjct: 65   EESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKP------G 118

Query: 410  WDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESG 469
              E S+     S  S + +    + +SS  S  ST + SR  ST    T +   S    G
Sbjct: 119  LSEKSTTFYS-SPRSPDTTHLPASMTSSGVSEESTTSHSRPGST---HTTAFPGSTTMPG 174

Query: 470  LSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKK---PISLGHP 526
            LS  S +   +P   +       + PG++      PE     S+ G  +    P +    
Sbjct: 175  LSQESTASHSSPGPTD-----TTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTAS 229

Query: 527  GSLKKGKTPPVAVTSPITHTAQSALKVAGK----------PEGKATDKGKLAVKNTGLQR 576
            G L+       +  SP  HT  S      +          P  K T        +  ++ 
Sbjct: 230  GLLEASMPVHSSTRSP--HTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEP 287

Query: 577  SSSDAGRDRLSDAKKPPSGI-ARPSTSG----SFGYKKPPPATGTA------TVMQTGGS 625
            S++  G    S +  P + I AR +TSG    S  Y   P +T T       T    G  
Sbjct: 288  STTSHG----SPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 343

Query: 626  ATLSKIQKSSGIPVKP-VNGRKTSLDVSNSAEPGFLAPGA---RSNIQYRSLPRPAKSSS 681
            +T S    +  I   P           S  + PG  A       S    RS    A  SS
Sbjct: 344  STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 403

Query: 682  MSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKA 741
               TG    P   ++S+   LL         S   E T +    TTP    ++       
Sbjct: 404  QDATGTIVLPARSTTSV---LLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSP 460

Query: 742  KAKAVALDSDNISLKSIGSPESTPKNQ--ASHPTATKLAELPPTPLRATAKSFVKPPSLA 799
            ++ A  L   + +   +    +T +++  ++H TA   +   P   R +  S   P S  
Sbjct: 461  RSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD 520

Query: 800  NLDKVNSNSLDLPSSSDTTHASKVPDLH------ATSSASGGPLPSCFTPSPA------- 846
                  S +   PS   TT  S            +T++ S G   + F  +P        
Sbjct: 521  TTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLF 580

Query: 847  PILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSST-PVP 905
            P    +S        + S    P+ T     LS    +   LQ   +     P+ST   P
Sbjct: 581  PDSTTSSGIVEASTRVHSSTGSPRTT-----LSPASSTSPGLQGESTAFQTHPASTHTTP 635

Query: 906  TPPAPPAAPTEEETEELTWSGSP--------RAGQLDSNQRDRNTL----PKKGLRYQLQ 953
            +PP+   AP EE T   T+  SP         A    S   +++T+    P         
Sbjct: 636  SPPSTATAPVEEST---TYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 692

Query: 954  SQEETKERRHSHTIGGLPESDDQSELPSPPALP-MSLSAKGQLTNIVSPTAATTPRITRS 1012
            +   T  R  S T    P S + + LP     P +S ++    ++  SPT   +P    S
Sbjct: 693  AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTS 752

Query: 1013 NSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSGSFRDPTDDVHGSVLSLASSASSTY- 1071
              +          S SQ GST S    P      G   + T  V+ S  S  S+ ++ + 
Sbjct: 753  LGVGEESTT----SRSQPGSTHSTVS-PASTTTPGLSEEST-TVYSS--SRGSTETTVFP 804

Query: 1072 SSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAET 1131
             S    +  E+         S+   + T  S  S       AF  S  +  + L     T
Sbjct: 805  HSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 864

Query: 1132 A---EEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSL 1188
            A   EE  T       T   L    S    ++ G    S  +P          S +  SL
Sbjct: 865  ADLGEESTTFPSSSGSTGTKLSPARSTTSGLV-GESTPSRLSPSSTETTTLPGSPTTPSL 923

Query: 1189 NSITSHSSIGSSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPD-SSA 1247
             S  S +   S +  DA      +       ++ +    P S  + +  +   T D S  
Sbjct: 924  -SEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQE 982

Query: 1248 PSSPKLQHGSTE-TASPSIKSSTSSSVGTDVTEGPAHP 1284
            P++     GSTE T SP   S+T+SS+G   T   + P
Sbjct: 983  PTTSHSSQGSTEATLSPG--STTASSLGQQSTTFHSSP 1018



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 165/802 (20%), Positives = 274/802 (34%), Gaps = 127/802 (15%)

Query: 347  MHGERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDD-- 404
            +HGE     H+ P  + + L   +       L  +         S    +  T+T  D  
Sbjct: 811  VHGEEPTTFHSRPASTHTTL--FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLG 868

Query: 405  -DITTGWDESSSISSGLSDASDNLS-----------SEEFNASSSLNSLPSTPTASRRNS 452
             + TT    S S  + LS A    S           S     +++L   P+TP+ S +++
Sbjct: 869  EESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST 928

Query: 453  TIVLRTDSEKRSLA-----ESGLSWFSESEEKAPKKL-------EYDSGSLKMEPGTSKW 500
            T      S   +L+      SG+S  S +    P             +  L  EP TS  
Sbjct: 929  TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHS 988

Query: 501  RRERPES--CDDSSKGGELKKPISLGH--PGSLKKGKTPPVAVTSPI------THTAQSA 550
             +   E+     S+    L +  +  H  PG  +    P   +TS +      TH++  +
Sbjct: 989  SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGS 1048

Query: 551  LKVAGKPEGKATDKGKLAVKNTGLQR--SSSDAGRDRLSDAKKPPSGIARPSTSGSFGYK 608
            L     P   +T  G L  ++T  Q   SSSD           PP   A P    +  + 
Sbjct: 1049 LHTTLTP-ASSTSAG-LQEESTTFQSWPSSSDT-------TPSPPGTTAAPVEVSTTYHS 1099

Query: 609  KPPPATGTATVMQTGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSA------EPGFLAP 662
            +P   + T T   +  S TL + ++S+ +   P     T+L  + SA      EP   +P
Sbjct: 1100 RP---SSTPTTHFSASSTTLGRSEESTTVHSSP-GATGTALFPTRSATSVLVGEP-TTSP 1154

Query: 663  GARSNIQYRSLPRPAKSSSMS--VTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTK 720
             +  + +  +LP    ++ +S   T     PR   +++ P+  ST   G++       ++
Sbjct: 1155 ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPA--STTSSGVSEESTTSHSR 1212

Query: 721  VASGRTTPAP-------VNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPT 773
              S  TT  P       V+Q       +        S   +  S   PEST  + +   T
Sbjct: 1213 PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGST 1272

Query: 774  ATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSAS 833
             T L      P   TA   ++  +  +    + ++   P+ S T            SS  
Sbjct: 1273 ETTL-----LPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKD 1327

Query: 834  GGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMS 893
              P P   T +   +   +  S S         S P            H S  S  +  S
Sbjct: 1328 TMPAPPTTTSAFVELSTTSHGSPS---------STPT----------THFSASSTTLGRS 1368

Query: 894  LPSAFPSSTPV--PTPPAPPAAPTEEETEELT-WSGSPRAGQLDSNQRDRNTLPKKGLRY 950
              S    S+PV   T P+P  + T    EE T +  SP + Q           P+     
Sbjct: 1369 EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQ-------TMHFPESSTAS 1421

Query: 951  QLQSQEETKERRHSHTIGGLPES-----DDQSELPSPPA------LPMSLSAKGQLTNIV 999
                +  T     +HTI   P +     ++ +   S P        P S +  G+     
Sbjct: 1422 GRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEE-- 1479

Query: 1000 SPTAATTPRITRSNSIPTH--------EAAFELYSGSQMGSTLSLAERPKGMIRSGSFRD 1051
            S  + ++P       +P H        E+     S   M +TL+      G+    +   
Sbjct: 1480 STASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTIL- 1538

Query: 1052 PTDDVHGSVLSLASSASSTYSS 1073
             T D+ G   +   S S TY++
Sbjct: 1539 YTSDLVGEPTTFYISPSPTYTT 1560


>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
           isoform 1 [Homo sapiens]
          Length = 1599

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 81/331 (24%), Positives = 125/331 (37%), Gaps = 50/331 (15%)

Query: 632 QKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNI-QYRSLPRPAKSSSMSVTGGRGG 690
           Q    I  + ++G +T+   +     G L P A     Q   + RP   S  ++   R G
Sbjct: 187 QGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPG 246

Query: 691 -PRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALD 749
            P P  S   PS         TPS              P+PV +   E   A    +++ 
Sbjct: 247 LPGPEHS---PSESQPSSPSPTPS--------------PSPVLEPGSEPNLA---VLSIP 286

Query: 750 SDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSL 809
            D ++   +   ESTP ++ +        E  PTPL   A+  ++     +     S   
Sbjct: 287 GDTMTTIQMSVEESTPISRETGEPYRLSPE--PTPL---AEPILEVEVTLSKPVPESEFS 341

Query: 810 DLPSSSDTTHASKVPDLH--------------ATSSASGGPLPSCFTPSPAPILNINSAS 855
             P  + T  AS   ++H                SS    P P+C + SP PI     A 
Sbjct: 342 SSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPI-----AP 396

Query: 856 FSQGLELMSGFSVPKETRMYPKLSGLHRSME--SLQMPMSLPSAFPSSTPVPTPPAPPAA 913
            +Q  EL++G   P    + P      ++ E  +   P ++PSA P++ P  T PA    
Sbjct: 397 TAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEE 456

Query: 914 PTEEETEELTWSGSPRAGQLDSNQRDRNTLP 944
             EEE EE   +G   AG+ +S +     LP
Sbjct: 457 MEEEEEEEEGEAG--EAGEAESEKGGEELLP 485


>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
           isoform 2 [Homo sapiens]
          Length = 1512

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 81/331 (24%), Positives = 125/331 (37%), Gaps = 50/331 (15%)

Query: 632 QKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNI-QYRSLPRPAKSSSMSVTGGRGG 690
           Q    I  + ++G +T+   +     G L P A     Q   + RP   S  ++   R G
Sbjct: 100 QGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPG 159

Query: 691 -PRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALD 749
            P P  S   PS         TPS              P+PV +   E   A    +++ 
Sbjct: 160 LPGPEHS---PSESQPSSPSPTPS--------------PSPVLEPGSEPNLA---VLSIP 199

Query: 750 SDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSL 809
            D ++   +   ESTP ++ +        E  PTPL   A+  ++     +     S   
Sbjct: 200 GDTMTTIQMSVEESTPISRETGEPYRLSPE--PTPL---AEPILEVEVTLSKPVPESEFS 254

Query: 810 DLPSSSDTTHASKVPDLH--------------ATSSASGGPLPSCFTPSPAPILNINSAS 855
             P  + T  AS   ++H                SS    P P+C + SP PI     A 
Sbjct: 255 SSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPI-----AP 309

Query: 856 FSQGLELMSGFSVPKETRMYPKLSGLHRSME--SLQMPMSLPSAFPSSTPVPTPPAPPAA 913
            +Q  EL++G   P    + P      ++ E  +   P ++PSA P++ P  T PA    
Sbjct: 310 TAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEE 369

Query: 914 PTEEETEELTWSGSPRAGQLDSNQRDRNTLP 944
             EEE EE   +G   AG+ +S +     LP
Sbjct: 370 MEEEEEEEEGEAG--EAGEAESEKGGEELLP 398


>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
           isoform 3 [Homo sapiens]
          Length = 1435

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 81/331 (24%), Positives = 125/331 (37%), Gaps = 50/331 (15%)

Query: 632 QKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNI-QYRSLPRPAKSSSMSVTGGRGG 690
           Q    I  + ++G +T+   +     G L P A     Q   + RP   S  ++   R G
Sbjct: 23  QGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPG 82

Query: 691 -PRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALD 749
            P P  S   PS         TPS              P+PV +   E   A    +++ 
Sbjct: 83  LPGPEHS---PSESQPSSPSPTPS--------------PSPVLEPGSEPNLA---VLSIP 122

Query: 750 SDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSL 809
            D ++   +   ESTP ++ +        E  PTPL   A+  ++     +     S   
Sbjct: 123 GDTMTTIQMSVEESTPISRETGEPYRLSPE--PTPL---AEPILEVEVTLSKPVPESEFS 177

Query: 810 DLPSSSDTTHASKVPDLH--------------ATSSASGGPLPSCFTPSPAPILNINSAS 855
             P  + T  AS   ++H                SS    P P+C + SP PI     A 
Sbjct: 178 SSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPI-----AP 232

Query: 856 FSQGLELMSGFSVPKETRMYPKLSGLHRSME--SLQMPMSLPSAFPSSTPVPTPPAPPAA 913
            +Q  EL++G   P    + P      ++ E  +   P ++PSA P++ P  T PA    
Sbjct: 233 TAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEE 292

Query: 914 PTEEETEELTWSGSPRAGQLDSNQRDRNTLP 944
             EEE EE   +G   AG+ +S +     LP
Sbjct: 293 MEEEEEEEEGEAG--EAGEAESEKGGEELLP 321


>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
           isoform 1 [Homo sapiens]
          Length = 1599

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 81/331 (24%), Positives = 125/331 (37%), Gaps = 50/331 (15%)

Query: 632 QKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNI-QYRSLPRPAKSSSMSVTGGRGG 690
           Q    I  + ++G +T+   +     G L P A     Q   + RP   S  ++   R G
Sbjct: 187 QGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPG 246

Query: 691 -PRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALD 749
            P P  S   PS         TPS              P+PV +   E   A    +++ 
Sbjct: 247 LPGPEHS---PSESQPSSPSPTPS--------------PSPVLEPGSEPNLA---VLSIP 286

Query: 750 SDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSL 809
            D ++   +   ESTP ++ +        E  PTPL   A+  ++     +     S   
Sbjct: 287 GDTMTTIQMSVEESTPISRETGEPYRLSPE--PTPL---AEPILEVEVTLSKPVPESEFS 341

Query: 810 DLPSSSDTTHASKVPDLH--------------ATSSASGGPLPSCFTPSPAPILNINSAS 855
             P  + T  AS   ++H                SS    P P+C + SP PI     A 
Sbjct: 342 SSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPI-----AP 396

Query: 856 FSQGLELMSGFSVPKETRMYPKLSGLHRSME--SLQMPMSLPSAFPSSTPVPTPPAPPAA 913
            +Q  EL++G   P    + P      ++ E  +   P ++PSA P++ P  T PA    
Sbjct: 397 TAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEE 456

Query: 914 PTEEETEELTWSGSPRAGQLDSNQRDRNTLP 944
             EEE EE   +G   AG+ +S +     LP
Sbjct: 457 MEEEEEEEEGEAG--EAGEAESEKGGEELLP 485


>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
           isoform 4 [Homo sapiens]
          Length = 1403

 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 79/321 (24%), Positives = 122/321 (38%), Gaps = 50/321 (15%)

Query: 642 VNGRKTSLDVSNSAEPGFLAPGARSNI-QYRSLPRPAKSSSMSVTGGRGG-PRPVSSSID 699
           ++G +T+   +     G L P A     Q   + RP   S  ++   R G P P  S   
Sbjct: 1   MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS--- 57

Query: 700 PSLLSTKQGGLTPSRLKEPTKVASGRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIG 759
           PS         TPS              P+PV +   E   A    +++  D ++   + 
Sbjct: 58  PSESQPSSPSPTPS--------------PSPVLEPGSEPNLA---VLSIPGDTMTTIQMS 100

Query: 760 SPESTPKNQASHPTATKLAELPPTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTH 819
             ESTP ++ +        E  PTPL   A+  ++     +     S     P  + T  
Sbjct: 101 VEESTPISRETGEPYRLSPE--PTPL---AEPILEVEVTLSKPVPESEFSSSPLQAPTPL 155

Query: 820 ASKVPDLH--------------ATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSG 865
           AS   ++H                SS    P P+C + SP PI     A  +Q  EL++G
Sbjct: 156 ASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPI-----APTAQPEELLNG 210

Query: 866 FSVPKETRMYPKLSGLHRSME--SLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELT 923
              P    + P      ++ E  +   P ++PSA P++ P  T PA      EEE EE  
Sbjct: 211 APSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEG 270

Query: 924 WSGSPRAGQLDSNQRDRNTLP 944
            +G   AG+ +S +     LP
Sbjct: 271 EAG--EAGEAESEKGGEELLP 289


>gi|30039694 zinc finger protein 598 [Homo sapiens]
          Length = 904

 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 120/547 (21%), Positives = 184/547 (33%), Gaps = 121/547 (22%)

Query: 448 SRRNSTIVLRTDSEKRSLAESGLSWFSESEEKAPKKLEYDSGSLKMEPGTSKWRRERPES 507
           SRR S    R + ++   A    S  ++ +E+A +  + + G              RP+ 
Sbjct: 329 SRRGSWRYKREEEDREVAAAVRASVAAQQQEEARRSEDQEEGG-------------RPKK 375

Query: 508 CDDSSKG-----GELKKPISLGH-PGSLKKGKTPPVAVTSPITHTAQSALKVAGKPEGKA 561
            + +++G     G  + P + G  PG  +     PV+  +  + T  +A    G P    
Sbjct: 376 EEAAARGPEDPRGPRRSPRTQGEGPGPKETSTNGPVSQEA-FSVTGPAAPGCVGVPGALP 434

Query: 562 TDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQ 621
               KL  K+      S+       + A   P G+A P            PA G +   +
Sbjct: 435 PPSPKL--KDEDFPSLSASTSSSCSTAATPGPVGLALPYAI---------PARGRSAFQE 483

Query: 622 TGGSATLSKIQKSSGIPVKPVNGRKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSS 681
               A +S + K    P   V+   +S      A+P   A    S        +P + + 
Sbjct: 484 EDFPALVSSVPKPGTAPTSLVSAWNSSSSSKKVAQPPLSAQATGSG-------QPTRKAG 536

Query: 682 MSVTGGRGGPRPVSSSIDPS-------LLSTKQGG----------LTPSRLKEPTKVAS- 723
               GGR G  P +   +         LLST+  G          + PS++ +  KV S 
Sbjct: 537 KGSRGGRKGGPPFTQEEEEDGGPALQELLSTRPTGSVSSTLGLASIQPSKVGKKKKVGSE 596

Query: 724 --GRTTPAPVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELP 781
             G T P P   T                      ++ +PE+ P ++A  P A  +    
Sbjct: 597 KPGTTLPQPPPAT------------------CPPGALQAPEA-PASRAEGPVAVVVNGHT 637

Query: 782 --PTPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHASKVPDLHATSSASGGPLPS 839
             P P R+  K   +PP L            L S    T     P L       GGP P 
Sbjct: 638 EGPAPARSAPK---EPPGLPR---------PLGSFPCPTPQEDFPAL-------GGPCPP 678

Query: 840 CFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFP 899
              P P          FS  + L+ G   P    + P +S               P  F 
Sbjct: 679 RMPPPPG---------FS-AVVLLKGTPPPPPPGLVPPIS-------------KPPPGFS 715

Query: 900 SSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETK 959
              P P P   P+  T   T+      +PRA  +  N R+RN    + +R  LQS E   
Sbjct: 716 GLLPSPHPACVPSPATTTTTKAPRLLPAPRAYLVPENFRERNLQLIQSIRDFLQSDEARF 775

Query: 960 ERRHSHT 966
               SH+
Sbjct: 776 SEFKSHS 782



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 17/68 (25%)

Query: 1227 GPKSASSYSDIEE-------------IATPDSSAPSSPKLQHGSTETASPSIKSSTSSSV 1273
            GPK  S+   + +             +  P +  P SPKL+    +   PS+ +STSSS 
Sbjct: 401  GPKETSTNGPVSQEAFSVTGPAAPGCVGVPGALPPPSPKLK----DEDFPSLSASTSSSC 456

Query: 1274 GTDVTEGP 1281
             T  T GP
Sbjct: 457  STAATPGP 464


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.126    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,268,869
Number of Sequences: 37866
Number of extensions: 4227870
Number of successful extensions: 27925
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 1002
Number of HSP's that attempted gapping in prelim test: 21881
Number of HSP's gapped (non-prelim): 6040
length of query: 1874
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1757
effective length of database: 13,817,196
effective search space: 24276813372
effective search space used: 24276813372
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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