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Search of human proteins with 26986534
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
(846 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 1713 0.0
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 422 e-118
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 386 e-107
gi|188497642 ARHGAP15 [Homo sapiens] 382 e-106
gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap... 318 1e-86
gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap... 318 1e-86
gi|122939151 Rho GTPase activating protein 9 isoform 2 [Homo sap... 239 6e-63
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 168 2e-41
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 148 2e-35
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 128 2e-29
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 128 2e-29
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 127 6e-29
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 127 6e-29
gi|23510413 sorting nexin 26 [Homo sapiens] 126 1e-28
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap... 125 1e-28
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap... 125 1e-28
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] 122 1e-27
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 122 2e-27
gi|229094128 active breakpoint cluster region-related protein i... 120 5e-27
gi|38679957 active breakpoint cluster region-related protein is... 120 5e-27
gi|38679954 active breakpoint cluster region-related protein is... 120 5e-27
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 119 1e-26
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 119 2e-26
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] 117 3e-26
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] 116 1e-25
gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo s... 114 3e-25
gi|4505507 oligophrenin 1 [Homo sapiens] 112 1e-24
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi... 112 2e-24
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 110 5e-24
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi... 108 2e-23
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 1713 bits (4437), Expect = 0.0
Identities = 846/846 (100%), Positives = 846/846 (100%)
Query: 1 MKMADRSGKIIPGQVYIEVEYDYEYEAKDRKIVIKQGERYILVKKTNDDWWQVKPDENSK 60
MKMADRSGKIIPGQVYIEVEYDYEYEAKDRKIVIKQGERYILVKKTNDDWWQVKPDENSK
Sbjct: 1 MKMADRSGKIIPGQVYIEVEYDYEYEAKDRKIVIKQGERYILVKKTNDDWWQVKPDENSK 60
Query: 61 AFYVPAQYVKEVTRKALMPPVKQVAGLPNNSTKIMQSLHLQRSTENVNKLPELSSFGKPS 120
AFYVPAQYVKEVTRKALMPPVKQVAGLPNNSTKIMQSLHLQRSTENVNKLPELSSFGKPS
Sbjct: 61 AFYVPAQYVKEVTRKALMPPVKQVAGLPNNSTKIMQSLHLQRSTENVNKLPELSSFGKPS 120
Query: 121 SSVQGTGLIRDANQNFGPSYNQGQTVNLSLDLTHNNGKFNNDSHSPKVSSQNRTRSFGHF 180
SSVQGTGLIRDANQNFGPSYNQGQTVNLSLDLTHNNGKFNNDSHSPKVSSQNRTRSFGHF
Sbjct: 121 SSVQGTGLIRDANQNFGPSYNQGQTVNLSLDLTHNNGKFNNDSHSPKVSSQNRTRSFGHF 180
Query: 181 PGPEFLDVEKTSFSQEQSCDSAGEGSERIHQDSESGDELSSSSTEQIRATTPPNQGRPDS 240
PGPEFLDVEKTSFSQEQSCDSAGEGSERIHQDSESGDELSSSSTEQIRATTPPNQGRPDS
Sbjct: 181 PGPEFLDVEKTSFSQEQSCDSAGEGSERIHQDSESGDELSSSSTEQIRATTPPNQGRPDS 240
Query: 241 PVYANLQELKISQSALPPLPGSPAIQINGEWETHKDSSGRCYYYNRGTQERTWKPPRWTR 300
PVYANLQELKISQSALPPLPGSPAIQINGEWETHKDSSGRCYYYNRGTQERTWKPPRWTR
Sbjct: 241 PVYANLQELKISQSALPPLPGSPAIQINGEWETHKDSSGRCYYYNRGTQERTWKPPRWTR 300
Query: 301 DASISKGDFQNPGDQELLSSEENYYSTSYSQSDSQCGSPPRGWSEELDERGHTLYTSDYT 360
DASISKGDFQNPGDQELLSSEENYYSTSYSQSDSQCGSPPRGWSEELDERGHTLYTSDYT
Sbjct: 301 DASISKGDFQNPGDQELLSSEENYYSTSYSQSDSQCGSPPRGWSEELDERGHTLYTSDYT 360
Query: 361 NEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKW 420
NEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKW
Sbjct: 361 NEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKW 420
Query: 421 RHSTIVLDTNDKESPTASKPCFPENESSPSSPKHQDTASSPKDQEKYGLLNVTKIAENGK 480
RHSTIVLDTNDKESPTASKPCFPENESSPSSPKHQDTASSPKDQEKYGLLNVTKIAENGK
Sbjct: 421 RHSTIVLDTNDKESPTASKPCFPENESSPSSPKHQDTASSPKDQEKYGLLNVTKIAENGK 480
Query: 481 KVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKK 540
KVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKK
Sbjct: 481 KVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKK 540
Query: 541 NVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDSPGIEKHDK 600
NVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDSPGIEKHDK
Sbjct: 541 NVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDSPGIEKHDK 600
Query: 601 EKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLAN 660
EKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLAN
Sbjct: 601 EKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLAN 660
Query: 661 LCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKW 720
LCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKW
Sbjct: 661 LCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKW 720
Query: 721 EDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQLPKPNQDTM 780
EDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQLPKPNQDTM
Sbjct: 721 EDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQLPKPNQDTM 780
Query: 781 QILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLEL 840
QILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLEL
Sbjct: 781 QILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLEL 840
Query: 841 SSIFGR 846
SSIFGR
Sbjct: 841 SSIFGR 846
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 422 bits (1084), Expect = e-118
Identities = 247/561 (44%), Positives = 339/561 (60%), Gaps = 51/561 (9%)
Query: 311 NPGDQELLSSEENYYS--TSYSQSD----SQCGSP--------PRGWSEELDERGHTLYT 356
+PGD + E +Y TSY + D G P P GWS + + LYT
Sbjct: 9 SPGDPRPPTPETDYPESLTSYPEEDYSPVGSFGEPGPTSPLTTPPGWSCHVSQDKQMLYT 68
Query: 357 SDYTNEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIV 416
+ +T E+W++ D G+ Y+Y+ + S WELP Q + RS+ + Q+
Sbjct: 69 NHFTQEQWVRLEDPHGKPYFYNPEDSSVRWELP--------QVPVPAPRSIHKSSQDG-- 118
Query: 417 LTKWRHSTIVLDTNDKESPTASK-PCFPENESSPSSPKHQDTASSPKDQEKYGLLNVTKI 475
DT + SP K P + S A K +K G+L+ TK
Sbjct: 119 -----------DTPAQASPPEEKVPAELDEVGSWEEVSPATAAVRTKTLDKAGVLHRTKT 167
Query: 476 AENGKKVRK-NWLSSWAVLQGSSLLFTKTQGSSTSWFG-----SNQSKPEFTVDLKGATI 529
A+ GK++RK +W +SW VL+G L F K S TS G S S PE+TV+L+GAT+
Sbjct: 168 ADKGKRLRKKHWSASWTVLEGGVLTFFKD--SKTSAAGGLRQPSKFSTPEYTVELRGATL 225
Query: 530 EMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETD-EGIEEE 588
A KDKSS+KNV EL++R G+E LIQ D++ +I+ W K ++ I + E E E
Sbjct: 226 SWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAQGIQELSAELPPEESESS 285
Query: 589 IPDSPGIEK----HDKEKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVR 644
D E+ +KE++ + + ++S + K + L+KFL RRPTLQ++R
Sbjct: 286 RVDFGSSERLGSWQEKEEDARPNAAAPALGPVGLES-DLSKVRHKLRKFLQRRPTLQSLR 344
Query: 645 EKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLR 704
EKGYIKDQVFG LA LC+RE VP+FV+ CI VE GLDIDG+YR+SGNLA IQKLR
Sbjct: 345 EKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLR 404
Query: 705 FAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVA 763
+ V+HDE+LDL+D +WED+HVITGALK+FFRELPEPLF F+HF F+ AIK Q+ +R
Sbjct: 405 YKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSR 464
Query: 764 AVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIA 823
V+DL+R LP PN DT+++LF+HL RVIE+GE+NRM+ QS+AIVFGPTLL+PE E ++
Sbjct: 465 CVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMP 524
Query: 824 VHTVYQNQIVELILLELSSIF 844
+ V+QNQ+VELIL + + IF
Sbjct: 525 MTMVFQNQVVELILQQCADIF 545
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 386 bits (992), Expect = e-107
Identities = 241/550 (43%), Positives = 327/550 (59%), Gaps = 56/550 (10%)
Query: 311 NPGDQELLSSEENYYS--TSYSQSD-SQCGSPPRGWSEELDERGHTLYTSDYTNEKWLKH 367
+PGD + E +Y TSY + D S GS E G T + T W H
Sbjct: 9 SPGDPRPPTPETDYPESLTSYPEEDYSPVGS--------FGEPGPTSPLT--TPPGWSCH 58
Query: 368 VDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVL 427
V Q +Q Y+ N +Q+Q + RS+ + Q+
Sbjct: 59 VS-QDKQMLYT-------------NHFTQEQVPVPAPRSIHKSSQDG------------- 91
Query: 428 DTNDKESPTASK-PCFPENESSPSSPKHQDTASSPKDQEKYGLLNVTKIAENGKKVRK-N 485
DT + SP K P + S A K +K G+L+ TK A+ GK++RK +
Sbjct: 92 DTPAQASPPEEKVPAELDEVGSWEEVSPATAAVRTKTLDKAGVLHRTKTADKGKRLRKKH 151
Query: 486 WLSSWAVLQGSSLLFTKTQGSSTSWFG-----SNQSKPEFTVDLKGATIEMASKDKSSKK 540
W +SW VL+G L F K S TS G S S PE+TV+L+GAT+ A KDKSS+K
Sbjct: 152 WSASWTVLEGGVLTFFKD--SKTSAAGGLRQPSKFSTPEYTVELRGATLSWAPKDKSSRK 209
Query: 541 NVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETD-EGIEEEIPDSPGIEK-- 597
NV EL++R G+E LIQ D++ +I+ W K ++ I + E E E D E+
Sbjct: 210 NVLELRSRDGSEYLIQHDSEAIISTWHKAIAQGIQELSAELPPEESESSRVDFGSSERLG 269
Query: 598 --HDKEKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFG 655
+KE++ + + ++S + K + L+KFL RRPTLQ++REKGYIKDQVFG
Sbjct: 270 SWQEKEEDARPNAAAPALGPVGLES-DLSKVRHKLRKFLQRRPTLQSLREKGYIKDQVFG 328
Query: 656 SNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDL 715
LA LC+RE VP+FV+ CI VE GLDIDG+YR+SGNLA IQKLR+ V+HDE+LDL
Sbjct: 329 CALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDL 388
Query: 716 NDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLIRQLPK 774
+D +WED+HVITGALK+FFRELPEPLF F+HF F+ AIK Q+ +R V+DL+R LP
Sbjct: 389 DDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLVRSLPA 448
Query: 775 PNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVE 834
PN DT+++LF+HL RVIE+GE+NRM+ QS+AIVFGPTLL+PE E ++ + V+QNQ+VE
Sbjct: 449 PNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPMTMVFQNQVVE 508
Query: 835 LILLELSSIF 844
LIL + + IF
Sbjct: 509 LILQQCADIF 518
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 382 bits (981), Expect = e-106
Identities = 204/393 (51%), Positives = 271/393 (68%), Gaps = 14/393 (3%)
Query: 465 EKYGLLNVTKIAENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDL 524
EK G L KIA+ GKK+RKNW +SW VL + F K KPE +VDL
Sbjct: 81 EKEGYLQKAKIADGGKKLRKNWSTSWIVLSSRRIEFYKESKQQALSNMKTGHKPE-SVDL 139
Query: 525 KGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETD-- 582
GA IE A K+KSS+KNVF++ T G E L+QSD D +I DWF + + I+ ++
Sbjct: 140 CGAHIEWA-KEKSSRKNVFQITTVSGNEFLLQSDIDFIILDWFHAIKNAIDRLPKDSSCP 198
Query: 583 ----EGIEEEIPDSPGIEKH---DKEKEQKDPKKLRSFKV--SSIDSSEQKKTKKNLKKF 633
E + + S + H D ++++ + +K F++ S+ D+S++ + K LKKF
Sbjct: 199 SRNLELFKIQRSSSTELLSHYDSDIKEQKPEHRKSLMFRLHHSASDTSDKNRVKSRLKKF 258
Query: 634 LTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRV 693
+TRRP+L+ ++EKG IKDQ+FGS+L +C+REN TVP FVK CIE VE+ GLD+DGIYRV
Sbjct: 259 ITRRPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQCIEAVEKRGLDVDGIYRV 318
Query: 694 SGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNA 753
SGNLA IQKLRF VN +EKL+L+DS+WEDIHV+TGALKMFFRELPEPLF ++ F FV A
Sbjct: 319 SGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEA 378
Query: 754 I-KQEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTL 812
I KQ+ R+ AVK L+++LP PN+DTM++LF HL +++ KN M+ QS+ IVFGPTL
Sbjct: 379 IKKQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTL 438
Query: 813 LKPEKETGNIAVHTVYQNQIVELILLELSSIFG 845
L+ E ETGN+A+H VYQNQI EL+L E S IFG
Sbjct: 439 LRAENETGNMAIHMVYQNQIAELMLSEYSKIFG 471
>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
sapiens]
Length = 731
Score = 318 bits (815), Expect = 1e-86
Identities = 193/520 (37%), Positives = 302/520 (58%), Gaps = 43/520 (8%)
Query: 362 EKWLKHVD-DQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTK- 419
+ W +H+D + GR +Y ++ W+ P+ + S + +++L R K
Sbjct: 217 DAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKG 276
Query: 420 WRHSTIVLDTNDKE-----SPTASKPCFPENESSPSSPKHQDTASSPKDQEKYGLLNVTK 474
+R T + D + S S+ P ++ P+ D P + EK GLLN+TK
Sbjct: 277 FRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLD---DPHEVEKSGLLNMTK 333
Query: 475 IAENGKKVRKNWLSSWAVLQGSSLLFTKTQGSS--TSWFGSNQSKPEFTVDLKGATIEMA 532
IA+ G+K+RKNW SW VL G+SL+F + + +S +G S+PE +VDL+GA +
Sbjct: 334 IAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHG 393
Query: 533 SKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDS 592
+ SS++NV ++T G E L+QSD++T + W + L + I + ++ + +E + S
Sbjct: 394 -RHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVI--ERLDRENPLELRLSGS 450
Query: 593 PGIEKHDKEKEQKD------PKKLRSFKVSSI---DSSEQKKTKKNLKKFLTRRPTLQAV 643
E E E+++ P S + SSI + +EQ + + LK+ + +RP LQ++
Sbjct: 451 GPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSL 510
Query: 644 REKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKL 703
+E+G ++DQVFG L +LCQRE TVP F++LCI V++ GLD+DGIYRVSGNLAV+QKL
Sbjct: 511 QERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKL 570
Query: 704 RFAVNHDE------------------KLDLNDSKWEDIHVITGALKMFFRELPEPLFTFN 745
RF V+ + +LDL+ ++W+DIHV+TGALK+F RELP+PL
Sbjct: 571 RFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPL 630
Query: 746 HFNDFVNAIK-QEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSI 804
F A+ E Q ++ +++LI +PKPN DT++ L HL RVI + +KNRMT ++
Sbjct: 631 LLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNL 690
Query: 805 AIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLELSSIF 844
IVFGPTL +PE+ET + A H +Y Q+V+L+L +S+F
Sbjct: 691 GIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLF 730
Score = 66.2 bits (160), Expect = 1e-10
Identities = 42/122 (34%), Positives = 58/122 (47%), Gaps = 10/122 (8%)
Query: 198 SCDSAGEGSERIHQDSESGDELSSSS--TEQIRATTPPNQGRPDSPVYANLQELKISQSA 255
S D+ + Q+ SG LS +E +T P + PVY NL +L+ +
Sbjct: 144 STDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRS 203
Query: 256 LPPLPGSPAIQINGEWETHKD-SSGRCYYYNRGTQERTWKPPRWTRDASISKGDFQNPGD 314
PP P P +Q WE H D +SGRC+Y N T ++WKPPR +R + NPG
Sbjct: 204 PPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSET-------NPGS 256
Query: 315 QE 316
E
Sbjct: 257 ME 258
Score = 43.1 bits (100), Expect = 0.001
Identities = 18/55 (32%), Positives = 35/55 (63%), Gaps = 4/55 (7%)
Query: 21 YDYEYEAKD-RKIVIKQGERYILVKKTNDDWW---QVKPDENSKAFYVPAQYVKE 71
Y + Y D +++ + +G+R++L++KTN DWW +++ S+ +VPA Y+ E
Sbjct: 31 YAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIE 85
>gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo
sapiens]
Length = 547
Score = 318 bits (815), Expect = 1e-86
Identities = 193/520 (37%), Positives = 302/520 (58%), Gaps = 43/520 (8%)
Query: 362 EKWLKHVD-DQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTK- 419
+ W +H+D + GR +Y ++ W+ P+ + S + +++L R K
Sbjct: 33 DAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKG 92
Query: 420 WRHSTIVLDTNDKE-----SPTASKPCFPENESSPSSPKHQDTASSPKDQEKYGLLNVTK 474
+R T + D + S S+ P ++ P+ D P + EK GLLN+TK
Sbjct: 93 FRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLD---DPHEVEKSGLLNMTK 149
Query: 475 IAENGKKVRKNWLSSWAVLQGSSLLFTKTQGSS--TSWFGSNQSKPEFTVDLKGATIEMA 532
IA+ G+K+RKNW SW VL G+SL+F + + +S +G S+PE +VDL+GA +
Sbjct: 150 IAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHG 209
Query: 533 SKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDS 592
+ SS++NV ++T G E L+QSD++T + W + L + I + ++ + +E + S
Sbjct: 210 -RHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVI--ERLDRENPLELRLSGS 266
Query: 593 PGIEKHDKEKEQKD------PKKLRSFKVSSI---DSSEQKKTKKNLKKFLTRRPTLQAV 643
E E E+++ P S + SSI + +EQ + + LK+ + +RP LQ++
Sbjct: 267 GPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSL 326
Query: 644 REKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKL 703
+E+G ++DQVFG L +LCQRE TVP F++LCI V++ GLD+DGIYRVSGNLAV+QKL
Sbjct: 327 QERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKL 386
Query: 704 RFAVNHDE------------------KLDLNDSKWEDIHVITGALKMFFRELPEPLFTFN 745
RF V+ + +LDL+ ++W+DIHV+TGALK+F RELP+PL
Sbjct: 387 RFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPL 446
Query: 746 HFNDFVNAIK-QEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSI 804
F A+ E Q ++ +++LI +PKPN DT++ L HL RVI + +KNRMT ++
Sbjct: 447 LLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNL 506
Query: 805 AIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLELSSIF 844
IVFGPTL +PE+ET + A H +Y Q+V+L+L +S+F
Sbjct: 507 GIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLF 546
Score = 60.1 bits (144), Expect = 8e-09
Identities = 32/79 (40%), Positives = 43/79 (54%), Gaps = 8/79 (10%)
Query: 239 DSPVYANLQELKISQSALPPLPGSPAIQINGEWETHKD-SSGRCYYYNRGTQERTWKPPR 297
+ PVY NL +L+ + PP P P +Q WE H D +SGRC+Y N T ++WKPPR
Sbjct: 3 EPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPR 62
Query: 298 WTRDASISKGDFQNPGDQE 316
+R + NPG E
Sbjct: 63 RSRSET-------NPGSME 74
>gi|122939151 Rho GTPase activating protein 9 isoform 2 [Homo
sapiens]
Length = 640
Score = 239 bits (611), Expect = 6e-63
Identities = 150/416 (36%), Positives = 237/416 (56%), Gaps = 42/416 (10%)
Query: 362 EKWLKHVD-DQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTK- 419
+ W +H+D + GR +Y ++ W+ P+ + S + +++L R K
Sbjct: 217 DAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKG 276
Query: 420 WRHSTIVLDTNDKE-----SPTASKPCFPENESSPSSPKHQDTASSPKDQEKYGLLNVTK 474
+R T + D + S S+ P ++ P+ D P + EK GLLN+TK
Sbjct: 277 FRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLD---DPHEVEKSGLLNMTK 333
Query: 475 IAENGKKVRKNWLSSWAVLQGSSLLFTKTQGSS--TSWFGSNQSKPEFTVDLKGATIEMA 532
IA+ G+K+RKNW SW VL G+SL+F + + +S +G S+PE +VDL+GA +
Sbjct: 334 IAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHG 393
Query: 533 SKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDS 592
+ SS++NV ++T G E L+QSD++T + W + L + I + ++ + +E + S
Sbjct: 394 -RHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVI--ERLDRENPLELRLSGS 450
Query: 593 PGIEKHDKEKEQKD------PKKLRSFKVSSI---DSSEQKKTKKNLKKFLTRRPTLQAV 643
E E E+++ P S + SSI + +EQ + + LK+ + +RP LQ++
Sbjct: 451 GPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSL 510
Query: 644 REKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKL 703
+E+G ++DQVFG L +LCQRE TVP F++LCI V++ GLD+DGIYRVSGNLAV+QKL
Sbjct: 511 QERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKL 570
Query: 704 RFAVNHDE------------------KLDLNDSKWEDIHVITGALKMFFRELPEPL 741
RF V+ + +LDL+ ++W+DIHV+TGALK+F RELP+PL
Sbjct: 571 RFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPL 626
Score = 66.2 bits (160), Expect = 1e-10
Identities = 42/122 (34%), Positives = 58/122 (47%), Gaps = 10/122 (8%)
Query: 198 SCDSAGEGSERIHQDSESGDELSSSS--TEQIRATTPPNQGRPDSPVYANLQELKISQSA 255
S D+ + Q+ SG LS +E +T P + PVY NL +L+ +
Sbjct: 144 STDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRS 203
Query: 256 LPPLPGSPAIQINGEWETHKD-SSGRCYYYNRGTQERTWKPPRWTRDASISKGDFQNPGD 314
PP P P +Q WE H D +SGRC+Y N T ++WKPPR +R + NPG
Sbjct: 204 PPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSET-------NPGS 256
Query: 315 QE 316
E
Sbjct: 257 ME 258
Score = 43.1 bits (100), Expect = 0.001
Identities = 18/55 (32%), Positives = 35/55 (63%), Gaps = 4/55 (7%)
Query: 21 YDYEYEAKD-RKIVIKQGERYILVKKTNDDWW---QVKPDENSKAFYVPAQYVKE 71
Y + Y D +++ + +G+R++L++KTN DWW +++ S+ +VPA Y+ E
Sbjct: 31 YAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIE 85
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 168 bits (425), Expect = 2e-41
Identities = 131/431 (30%), Positives = 209/431 (48%), Gaps = 50/431 (11%)
Query: 446 ESSPSSPKHQDTASSP-KDQEKYGLLNVTK-IAENGKKVR---KNWLSSWAVLQGSSLLF 500
+SS S +D++S D K G L+ + + GK+V + W + VL+G SL
Sbjct: 913 KSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGHSLYL 972
Query: 501 TKTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDND 560
K + T+ S+ E + + I++ S ++ +KNVF L T E L Q+++
Sbjct: 973 YKDKREQTT-----PSEEEQPISVNACLIDI-SYSETKRKNVFRLTTSD-CECLFQAEDR 1025
Query: 561 TVINDWFKVLSSTINNQAVETDEGIE-------------------EEIPDSP-------- 593
+ W K + + N E D G+ E++P +P
Sbjct: 1026 DDMLAWIKTIQESSNLN--EEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLSIRQ 1083
Query: 594 ---GIEKHDKEKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIK 650
G + K + PK+ K+ S D + K K +K + ++ EK
Sbjct: 1084 TLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPS--IMRKTFEKKPTA 1141
Query: 651 DQVFGSNLANLCQRE-NGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNH 709
FG L + N +P V +C + VEE GL+ GIYRV GN A I ++ +N
Sbjct: 1142 TGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNK 1201
Query: 710 D-EKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAI-KQEPRQRVAAVKD 767
+D+ D KW D++VI+ LK FFR+LPEPLFT + + DF+ A K++P R+ +K
Sbjct: 1202 GMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKR 1261
Query: 768 LIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLK-PEKETGNIAVHT 826
LI LP+ + +T++ L HL+ V EN EKN+M +++AIVFGPTL++ E ++ H
Sbjct: 1262 LIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHM 1321
Query: 827 VYQNQIVELIL 837
Q +IVE ++
Sbjct: 1322 PDQYKIVETLI 1332
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 148 bits (374), Expect = 2e-35
Identities = 110/397 (27%), Positives = 195/397 (49%), Gaps = 41/397 (10%)
Query: 475 IAENGKKVR---KNWLSSWAVLQGSSLLFTKTQ--------GSSTSWFGSNQSKPEFTVD 523
+ + GKK + W +A L+ SL +K + G++ + G +++ P
Sbjct: 607 LTKKGKKAGSGLRQWKRVYAALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCI-- 664
Query: 524 LKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDE 583
G+ + S ++ +++VF L T E L Q+++ + W + + N++A D
Sbjct: 665 --GSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRE--NSRAEGEDP 720
Query: 584 GIEEEIPDSPGIEKHDKEKEQKDPKKLRSFKVS-SIDSSEQKKTKKNLKKFLTRRPT--- 639
G + S + + K PK S K S + + + K++ + L +
Sbjct: 721 GCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQSAARGLRTQDLPAG 780
Query: 640 --------------LQAVREKGYIKDQVFGSNLANLCQ--RENGTVPKFVKLCIEHVEEH 683
+ +++ + FG L CQ EN VP V C VE
Sbjct: 781 SKDDSAAAPKTPWGINIIKKNKKAAPRAFGVRLEE-CQPATENQRVPLIVAACCRIVEAR 839
Query: 684 GLDIDGIYRVSGNLAVIQKLRFAVNHDE-KLDLNDSKWEDIHVITGALKMFFRELPEPLF 742
GL+ GIYRV GN AV+ L+ +N ++L D +W+D++VI+ LK FFR+LPEPLF
Sbjct: 840 GLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNVISSLLKSFFRKLPEPLF 899
Query: 743 TFNHFNDFVNAIK-QEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTY 801
T + +NDF+ A + ++ R+R+ ++ LIR LP +T++ L HL+ + ++ EKN+M
Sbjct: 900 TDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEP 959
Query: 802 QSIAIVFGPTLLK-PEKETGNIAVHTVYQNQIVELIL 837
+++A+VFGPTL++ E ++ H + +IVE ++
Sbjct: 960 RNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLI 996
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 128 bits (322), Expect = 2e-29
Identities = 66/189 (34%), Positives = 120/189 (63%), Gaps = 3/189 (1%)
Query: 652 QVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHD- 710
+V+ +L L + N P V +CI +E GL +G+YRVSG I+ ++ A + D
Sbjct: 273 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 332
Query: 711 EKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLI 769
EK D++ + + DI++ITGALK++FR+LP P+ T++ ++ F++A K +R+ AV +++
Sbjct: 333 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 392
Query: 770 RQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTV-Y 828
LP + +T++ L HL++V N + N M +++ IVFGPTL++P +++ +H + Y
Sbjct: 393 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRY 452
Query: 829 QNQIVELIL 837
Q IV++++
Sbjct: 453 QKLIVQILI 461
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 128 bits (322), Expect = 2e-29
Identities = 66/189 (34%), Positives = 120/189 (63%), Gaps = 3/189 (1%)
Query: 652 QVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHD- 710
+V+ +L L + N P V +CI +E GL +G+YRVSG I+ ++ A + D
Sbjct: 137 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 196
Query: 711 EKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLI 769
EK D++ + + DI++ITGALK++FR+LP P+ T++ ++ F++A K +R+ AV +++
Sbjct: 197 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 256
Query: 770 RQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTV-Y 828
LP + +T++ L HL++V N + N M +++ IVFGPTL++P +++ +H + Y
Sbjct: 257 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRY 316
Query: 829 QNQIVELIL 837
Q IV++++
Sbjct: 317 QKLIVQILI 325
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 127 bits (318), Expect = 6e-29
Identities = 65/196 (33%), Positives = 122/196 (62%), Gaps = 3/196 (1%)
Query: 652 QVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHD- 710
+V+ +L L + P V +CI +E GL+ +G+YRVSG +I+ ++ A + D
Sbjct: 264 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDG 323
Query: 711 EKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLI 769
EK D++ + +EDI++ITGALK++FR+LP PL T++ + F+ + K +P +++ + + +
Sbjct: 324 EKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 383
Query: 770 RQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTV-Y 828
+ LP + +T++ L HL+RV + ++N M +++ IVFGPTL++ + A++ + Y
Sbjct: 384 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRY 443
Query: 829 QNQIVELILLELSSIF 844
Q +VEL++ +F
Sbjct: 444 QRLVVELLIKNEDILF 459
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 127 bits (318), Expect = 6e-29
Identities = 65/196 (33%), Positives = 122/196 (62%), Gaps = 3/196 (1%)
Query: 652 QVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHD- 710
+V+ +L L + P V +CI +E GL+ +G+YRVSG +I+ ++ A + D
Sbjct: 238 KVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDG 297
Query: 711 EKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLI 769
EK D++ + +EDI++ITGALK++FR+LP PL T++ + F+ + K +P +++ + + +
Sbjct: 298 EKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 357
Query: 770 RQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTV-Y 828
+ LP + +T++ L HL+RV + ++N M +++ IVFGPTL++ + A++ + Y
Sbjct: 358 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRY 417
Query: 829 QNQIVELILLELSSIF 844
Q +VEL++ +F
Sbjct: 418 QRLVVELLIKNEDILF 433
>gi|23510413 sorting nexin 26 [Homo sapiens]
Length = 1126
Score = 126 bits (316), Expect = 1e-28
Identities = 75/223 (33%), Positives = 127/223 (56%), Gaps = 9/223 (4%)
Query: 630 LKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDG 689
L+ F+ RP+ Q +R++G ++ +VFG +L VP+ ++ C E +E HG+ +DG
Sbjct: 289 LRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGV-VDG 347
Query: 690 IYRVSGNLAVIQKLRFAVNHDEKLDLNDSKW-EDIHVITGALKMFFRELPEPLFTFNHFN 748
IYR+SG + IQ+LR + + +L+ + +DIH ++ K++FRELP PL T+ +
Sbjct: 348 IYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYG 407
Query: 749 DFVNAIKQE-PRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIV 807
F A+ +R+ V D+I+QLP P+ T++ L RHL R+ + M +++AIV
Sbjct: 408 KFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIV 467
Query: 808 FGPTLLKP-EKET----GNIAVHTV-YQNQIVELILLELSSIF 844
+ P LL+ E E+ G A V Q+ +VE +L + +F
Sbjct: 468 WAPNLLRSMELESVGMGGAAAFREVRVQSVVVEFLLTHVDVLF 510
>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
sapiens]
Length = 890
Score = 125 bits (315), Expect = 1e-28
Identities = 78/214 (36%), Positives = 122/214 (57%), Gaps = 11/214 (5%)
Query: 641 QAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVI 700
Q ++KG K++VFG +L Q VP+ +K C E VEE+G+ +DGIYR+SG + I
Sbjct: 5 QKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGV-VDGIYRLSGVSSNI 63
Query: 701 QKLRFAVNHDEKLDLN-DSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAI--KQE 757
QKLR + K DL D +DIH ++ K +FRELP+PL T+ ++ F A+ + E
Sbjct: 64 QKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLE 123
Query: 758 PRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEK 817
P +R+ + +++R+LP PN T++ L RHL + + M +++AIV+ P LL+ +
Sbjct: 124 P-ERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKD 182
Query: 818 -----ETGNIAVHTV-YQNQIVELILLELSSIFG 845
G A V Q+ +VE IL + +FG
Sbjct: 183 IEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFG 216
>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
sapiens]
Length = 1101
Score = 125 bits (315), Expect = 1e-28
Identities = 78/214 (36%), Positives = 122/214 (57%), Gaps = 11/214 (5%)
Query: 641 QAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVI 700
Q ++KG K++VFG +L Q VP+ +K C E VEE+G+ +DGIYR+SG + I
Sbjct: 5 QKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGV-VDGIYRLSGVSSNI 63
Query: 701 QKLRFAVNHDEKLDLN-DSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAI--KQE 757
QKLR + K DL D +DIH ++ K +FRELP+PL T+ ++ F A+ + E
Sbjct: 64 QKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVGVQLE 123
Query: 758 PRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEK 817
P +R+ + +++R+LP PN T++ L RHL + + M +++AIV+ P LL+ +
Sbjct: 124 P-ERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKD 182
Query: 818 -----ETGNIAVHTV-YQNQIVELILLELSSIFG 845
G A V Q+ +VE IL + +FG
Sbjct: 183 IEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFG 216
>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
Length = 2087
Score = 122 bits (306), Expect = 1e-27
Identities = 78/249 (31%), Positives = 135/249 (54%), Gaps = 10/249 (4%)
Query: 604 QKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQ 663
QK P+ + + V S + K L+ F+ RPT Q ++++G +K++VFG +L
Sbjct: 321 QKVPQSVTN-SVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLL 379
Query: 664 RENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKW-ED 722
VP+ ++ C +E +G+ +DGIYR+SG + IQ+LR + + DL + +D
Sbjct: 380 NSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQD 438
Query: 723 IHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLIRQLPKPNQDTMQ 781
IH + K++FRELP PL T+ + F +A+ +R+ + D+I+QLP P+ T++
Sbjct: 439 IHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLE 498
Query: 782 ILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEK-----ETGNIAVHTV-YQNQIVEL 835
L RHL + + M +++AIV+ P LL+ ++ +G A V Q+ +VE
Sbjct: 499 FLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEF 558
Query: 836 ILLELSSIF 844
IL + +F
Sbjct: 559 ILNHVDVLF 567
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 122 bits (305), Expect = 2e-27
Identities = 74/224 (33%), Positives = 125/224 (55%), Gaps = 10/224 (4%)
Query: 624 KKTKKNLKKFLTR-RPTL-QAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVE 681
+ ++N KK + RP++ +A E Y FG L + E +P F++ CIE++E
Sbjct: 1220 RSLRRNTKKPKPKPRPSITKATWESNY-----FGVPLTTVVTPEK-PIPIFIERCIEYIE 1273
Query: 682 EHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPL 741
GL +GIYRVSGN + ++ L+ + D LDL + + ++ + GA+K FF ELP+PL
Sbjct: 1274 ATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFT-VNTVAGAMKSFFSELPDPL 1332
Query: 742 FTFNHFNDFVNAIKQEPR-QRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMT 800
+N D V A K R Q++ A+K+++++ PK N + + + HL +V N + N MT
Sbjct: 1333 VPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMT 1392
Query: 801 YQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLELSSIF 844
++++I F PTL++P+ T + T I+EL + + F
Sbjct: 1393 SENLSICFWPTLMRPDFSTMDALTATRTYQTIIELFIQQCPFFF 1436
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 120 bits (301), Expect = 5e-27
Identities = 75/190 (39%), Positives = 107/190 (56%), Gaps = 9/190 (4%)
Query: 632 KFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIY 691
KF +R +L+ K + VFG ++ + +RE VP V+ C+E VE+ G++ GIY
Sbjct: 579 KFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIY 636
Query: 692 RVSGNLAVIQKLRF---AVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFN 748
R+SG IQ L+ A N D L L+D DI+ I G LK++FRELPEPL T +
Sbjct: 637 RISGVATDIQALKAVFDANNKDILLMLSDM---DINAIAGTLKLYFRELPEPLLTDRLYP 693
Query: 749 DFVNAIK-QEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIV 807
F+ I +P + + L+R LP PN T L HL+RV E N+M+ ++A V
Sbjct: 694 AFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 753
Query: 808 FGPTLLKPEK 817
FGPTLL+P +
Sbjct: 754 FGPTLLRPSE 763
>gi|38679957 active breakpoint cluster region-related protein
isoform a [Homo sapiens]
Length = 859
Score = 120 bits (301), Expect = 5e-27
Identities = 75/190 (39%), Positives = 107/190 (56%), Gaps = 9/190 (4%)
Query: 632 KFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIY 691
KF +R +L+ K + VFG ++ + +RE VP V+ C+E VE+ G++ GIY
Sbjct: 625 KFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIY 682
Query: 692 RVSGNLAVIQKLRF---AVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFN 748
R+SG IQ L+ A N D L L+D DI+ I G LK++FRELPEPL T +
Sbjct: 683 RISGVATDIQALKAVFDANNKDILLMLSDM---DINAIAGTLKLYFRELPEPLLTDRLYP 739
Query: 749 DFVNAIK-QEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIV 807
F+ I +P + + L+R LP PN T L HL+RV E N+M+ ++A V
Sbjct: 740 AFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 799
Query: 808 FGPTLLKPEK 817
FGPTLL+P +
Sbjct: 800 FGPTLLRPSE 809
>gi|38679954 active breakpoint cluster region-related protein
isoform b [Homo sapiens]
Length = 822
Score = 120 bits (301), Expect = 5e-27
Identities = 75/190 (39%), Positives = 107/190 (56%), Gaps = 9/190 (4%)
Query: 632 KFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIY 691
KF +R +L+ K + VFG ++ + +RE VP V+ C+E VE+ G++ GIY
Sbjct: 588 KFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIY 645
Query: 692 RVSGNLAVIQKLRF---AVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFN 748
R+SG IQ L+ A N D L L+D DI+ I G LK++FRELPEPL T +
Sbjct: 646 RISGVATDIQALKAVFDANNKDILLMLSDM---DINAIAGTLKLYFRELPEPLLTDRLYP 702
Query: 749 DFVNAIK-QEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIV 807
F+ I +P + + L+R LP PN T L HL+RV E N+M+ ++A V
Sbjct: 703 AFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 762
Query: 808 FGPTLLKPEK 817
FGPTLL+P +
Sbjct: 763 FGPTLLRPSE 772
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 119 bits (298), Expect = 1e-26
Identities = 83/228 (36%), Positives = 130/228 (57%), Gaps = 16/228 (7%)
Query: 600 KEKEQKDPKKLRSFK----VSSIDSSEQKKTKK-NLKKFLTRRPTLQAVREKGYIKDQVF 654
K + Q DP+ L+ V +++ E K + K N ++F +R + + ++ G VF
Sbjct: 1000 KGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKR--MPSRKQTG-----VF 1052
Query: 655 GSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLD 714
G +A + +RE VP V+ C+E +E G++ GIYRVSG IQ L+ A + + K D
Sbjct: 1053 GVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK-D 1111
Query: 715 LNDSKWE-DIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLIRQL 772
++ E D++ I G LK++FRELPEPLFT + +F I +P + + + +L+ L
Sbjct: 1112 VSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSL 1171
Query: 773 PKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKP-EKET 819
P+ N T L HL+RV E N+M+ ++A VFGPTLL+P EKE+
Sbjct: 1172 PEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKES 1219
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 119 bits (297), Expect = 2e-26
Identities = 70/170 (41%), Positives = 103/170 (60%), Gaps = 4/170 (2%)
Query: 653 VFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEK 712
VFG +A + +RE VP V+ C+E +E G++ GIYRVSG IQ L+ A + + K
Sbjct: 1007 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 1066
Query: 713 LDLNDSKWE-DIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLIR 770
D++ E D++ I G LK++FRELPEPLFT + +F I +P + + + +L+
Sbjct: 1067 -DVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLL 1125
Query: 771 QLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKP-EKET 819
LP+ N T L HL+RV E N+M+ ++A VFGPTLL+P EKE+
Sbjct: 1126 SLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKES 1175
>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
Length = 1738
Score = 117 bits (294), Expect = 3e-26
Identities = 70/216 (32%), Positives = 121/216 (56%), Gaps = 9/216 (4%)
Query: 637 RPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGN 696
RPT Q ++++G +K++VFG +L VP+ ++ C +E +G+ +DGIYR+SG
Sbjct: 4 RPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGV 62
Query: 697 LAVIQKLRFAVNHDEKLDLNDSKW-EDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK 755
+ IQ+LR + + DL + +DIH + K++FRELP PL T+ + F +A+
Sbjct: 63 ASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVS 122
Query: 756 QEP-RQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLK 814
+R+ + D+I+QLP P+ T++ L RHL + + M +++AIV+ P LL+
Sbjct: 123 AATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLR 182
Query: 815 PEK-----ETGNIAVHTV-YQNQIVELILLELSSIF 844
++ +G A V Q+ +VE IL + +F
Sbjct: 183 SKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLF 218
>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
Length = 786
Score = 116 bits (290), Expect = 1e-25
Identities = 62/176 (35%), Positives = 102/176 (57%), Gaps = 4/176 (2%)
Query: 673 VKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLR---FAVNHDEKLDLNDSKWEDIHVITGA 729
++ CI VE G++ G+YRV G + +Q+L V ++DL +S ++ IT A
Sbjct: 399 IRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSA 458
Query: 730 LKMFFRELPEPLFTFNHFNDFVNAIKQ-EPRQRVAAVKDLIRQLPKPNQDTMQILFRHLR 788
LK + R LPEPL T+ DF+ K P RV A+ L+ +LP+ N++ + IL +HL
Sbjct: 459 LKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLT 518
Query: 789 RVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLELSSIF 844
V + ++N MT ++ +VFGPTL++P++ET + +QN +VE+++ IF
Sbjct: 519 NVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAALMDLKFQNIVVEILIENHEKIF 574
>gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo
sapiens]
Length = 874
Score = 114 bits (286), Expect = 3e-25
Identities = 61/177 (34%), Positives = 106/177 (59%), Gaps = 5/177 (2%)
Query: 672 FVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLR---FAVNHDEKLDLNDSKWEDIHVITG 728
FV+ CI+ VE G+ I G+YR+ G + +QKL F+ +D++ W++ IT
Sbjct: 397 FVRKCIQAVETRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDIDIDIELWDN-KTITS 455
Query: 729 ALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQ-RVAAVKDLIRQLPKPNQDTMQILFRHL 787
LK + R L EPL T+ DF+ A+K + + RV AV L+ +LP+ N++ + IL +HL
Sbjct: 456 GLKNYLRCLAEPLMTYKLHKDFIIAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHL 515
Query: 788 RRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLELSSIF 844
+V + ++N MT ++ ++FGPTL++ ++ET ++ +QN +VE+++ IF
Sbjct: 516 VKVSLHSQQNLMTVSNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIF 572
>gi|4505507 oligophrenin 1 [Homo sapiens]
Length = 802
Score = 112 bits (281), Expect = 1e-24
Identities = 64/201 (31%), Positives = 116/201 (57%), Gaps = 8/201 (3%)
Query: 650 KDQVFGSNLANLCQRENGTVP-KFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVN 708
K+ ++ S + + E V KFV+ CI +E G+ +G+YR G+ +QKL A
Sbjct: 366 KEPIYHSPITKQQEMELNEVGFKFVRKCINIIETKGIKTEGLYRTVGSNIQVQKLLNAF- 424
Query: 709 HDEK----LDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQ-RVA 763
D K +D ++S W DI IT +LK + R L EP+ T+ + V+A K + R+
Sbjct: 425 FDPKCPGDVDFHNSDW-DIKTITSSLKFYLRNLSEPVMTYRLHKELVSAAKSDNLDYRLG 483
Query: 764 AVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIA 823
A+ L+ +LP+ N++ +++L RHL V E+ ++N MT ++ ++FGPTL++ +++T
Sbjct: 484 AIHSLVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAM 543
Query: 824 VHTVYQNQIVELILLELSSIF 844
++ +QN +VE+++ I+
Sbjct: 544 MNIKFQNIVVEILIEHFGKIY 564
>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapiens]
Length = 1502
Score = 112 bits (279), Expect = 2e-24
Identities = 74/255 (29%), Positives = 124/255 (48%), Gaps = 18/255 (7%)
Query: 591 DSPGIEKHDKEKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIK 650
D+P I + ++K KK K E KK KK K F P + E Y
Sbjct: 1212 DNPAITSDQELDDKKMKKKTHKVK-------EDKKQKKKTKNF---NPPTRRNWESNY-- 1259
Query: 651 DQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHD 710
FG L +L E +P FV+ C+E +E+ GL +G+YRVSGN ++ + D
Sbjct: 1260 ---FGMPLQDLVTAEK-PIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQD 1315
Query: 711 EKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLI 769
++L + ++ + GALK FF +LP+PL ++ + + A K + +R+ A+K+++
Sbjct: 1316 HNINLVSME-VTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIV 1374
Query: 770 RQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQ 829
++ N D + + HL RV + + N MT +++I F PTL++P+ E T
Sbjct: 1375 KKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIH 1434
Query: 830 NQIVELILLELSSIF 844
+VE + + F
Sbjct: 1435 QSVVETFIQQCQFFF 1449
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 110 bits (275), Expect = 5e-24
Identities = 68/212 (32%), Positives = 113/212 (53%), Gaps = 11/212 (5%)
Query: 641 QAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVI 700
Q ++ KG FG +L + VP +K C E +E HG+ +DGIYR+SG + I
Sbjct: 8 QKLKRKGAAS--AFGCDLTEYLESSGQDVPYVLKSCAEFIETHGI-VDGIYRLSGVTSNI 64
Query: 701 QKLRFAVNHDEKLDLNDSKW-EDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPR 759
Q+LR D+ DL + +DIH + K++FRELP PL T+ + F A+ P
Sbjct: 65 QRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPE 124
Query: 760 Q-RVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKE 818
+ ++A ++++I++LP + T++ L RHL + K M +++A+V+ P LL+ ++
Sbjct: 125 EGQLARIQNVIQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKEI 184
Query: 819 -----TGNIAVHTV-YQNQIVELILLELSSIF 844
G+ A V Q ++E IL + IF
Sbjct: 185 EATGCNGDAAFLAVRVQQVVIEFILNHVDQIF 216
>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapiens]
Length = 1501
Score = 108 bits (271), Expect = 2e-23
Identities = 73/255 (28%), Positives = 125/255 (49%), Gaps = 19/255 (7%)
Query: 591 DSPGIEKHDKEKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIK 650
D+P I D+E + K KK K + ++KK KN P + E Y
Sbjct: 1212 DNPAITS-DQELDDKKMKK----KTHKVKEDKKKKKTKNFN------PPTRRNWESNY-- 1258
Query: 651 DQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHD 710
FG L +L E +P FV+ C+E +E+ GL +G+YRVSGN ++ + D
Sbjct: 1259 ---FGMPLQDLVTAEK-PIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQD 1314
Query: 711 EKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLI 769
++L + ++ + GALK FF +LP+PL ++ + + A K + +R+ A+K+++
Sbjct: 1315 HNINLVSME-VTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIV 1373
Query: 770 RQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQ 829
++ N D + + HL RV + + N MT +++I F PTL++P+ E T
Sbjct: 1374 KKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIH 1433
Query: 830 NQIVELILLELSSIF 844
+VE + + F
Sbjct: 1434 QSVVETFIQQCQFFF 1448
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,591,494
Number of Sequences: 37866
Number of extensions: 1700387
Number of successful extensions: 6631
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 163
Number of HSP's successfully gapped in prelim test: 145
Number of HSP's that attempted gapping in prelim test: 5854
Number of HSP's gapped (non-prelim): 650
length of query: 846
length of database: 18,247,518
effective HSP length: 111
effective length of query: 735
effective length of database: 14,044,392
effective search space: 10322628120
effective search space used: 10322628120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.