Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 26667222

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|26667222 eyes absent 1 isoform a [Homo sapiens]
         (559 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|26667222 eyes absent 1 isoform a [Homo sapiens]                   1137   0.0  
gi|19923100 eyes absent 1 isoform b [Homo sapiens]                   1122   0.0  
gi|26667216 eyes absent 1 isoform b [Homo sapiens]                   1122   0.0  
gi|26667219 eyes absent 1 isoform c [Homo sapiens]                   1029   0.0  
gi|98991763 eyes absent 4 isoform b [Homo sapiens]                    817   0.0  
gi|98991760 eyes absent 4 isoform a [Homo sapiens]                    817   0.0  
gi|26667257 eyes absent 4 isoform d [Homo sapiens]                    801   0.0  
gi|26667227 eyes absent 2 isoform a [Homo sapiens]                    684   0.0  
gi|26667240 eyes absent 2 isoform b [Homo sapiens]                    684   0.0  
gi|26667235 eyes absent 2 isoform a [Homo sapiens]                    684   0.0  
gi|26667232 eyes absent 2 isoform a [Homo sapiens]                    684   0.0  
gi|26667230 eyes absent 2 isoform c [Homo sapiens]                    644   0.0  
gi|26667243 eyes absent 3 [Homo sapiens]                              548   e-156
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s...    60   5e-09
gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s...    55   2e-07
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s...    55   2e-07
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap...    55   2e-07
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s...    53   6e-07
gi|5454064 RNA binding motif protein 14 [Homo sapiens]                 52   2e-06
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...    49   9e-06
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    49   2e-05
gi|167736355 mucin 4 isoform a [Homo sapiens]                          47   4e-05
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             45   2e-04
gi|161016767 mucin 21 [Homo sapiens]                                   44   3e-04
gi|151301154 mucin 6, gastric [Homo sapiens]                           44   4e-04
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap...    44   4e-04
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap...    44   4e-04
gi|54607108 zinc finger, MIZ-type containing 2 isoform 1 [Homo s...    44   5e-04
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          43   7e-04
gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom...    43   7e-04

>gi|26667222 eyes absent 1 isoform a [Homo sapiens]
          Length = 559

 Score = 1137 bits (2942), Expect = 0.0
 Identities = 559/559 (100%), Positives = 559/559 (100%)

Query: 1   MLLFPQVAVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRP 60
           MLLFPQVAVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRP
Sbjct: 1   MLLFPQVAVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRP 60

Query: 61  YPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLS 120
           YPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLS
Sbjct: 61  YPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLS 120

Query: 121 QSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQ 180
           QSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQ
Sbjct: 121 QSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQ 180

Query: 181 DYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDP 240
           DYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDP
Sbjct: 181 DYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDP 240

Query: 241 TAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETI 300
           TAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETI
Sbjct: 241 TAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETI 300

Query: 301 IVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSD 360
           IVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSD
Sbjct: 301 IVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSD 360

Query: 361 DNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVG 420
           DNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVG
Sbjct: 361 DNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVG 420

Query: 421 GLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVL 480
           GLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVL
Sbjct: 421 GLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVL 480

Query: 481 LYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWR 540
           LYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWR
Sbjct: 481 LYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWR 540

Query: 541 ISSHSDLMALHHALELEYL 559
           ISSHSDLMALHHALELEYL
Sbjct: 541 ISSHSDLMALHHALELEYL 559


>gi|19923100 eyes absent 1 isoform b [Homo sapiens]
          Length = 592

 Score = 1122 bits (2903), Expect = 0.0
 Identities = 551/551 (100%), Positives = 551/551 (100%)

Query: 9   VKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTP 68
           VKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTP
Sbjct: 42  VKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTP 101

Query: 69  SSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQT 128
           SSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQT
Sbjct: 102 SSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQT 161

Query: 129 GFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSF 188
           GFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSF
Sbjct: 162 GFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSF 221

Query: 189 GQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIH 248
           GQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIH
Sbjct: 222 GQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIH 281

Query: 249 SPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLT 308
           SPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLT
Sbjct: 282 SPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLT 341

Query: 309 GSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLST 368
           GSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLST
Sbjct: 342 GSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLST 401

Query: 369 YNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKR 428
           YNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKR
Sbjct: 402 YNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKR 461

Query: 429 EAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVF 488
           EAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVF
Sbjct: 462 EAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVF 521

Query: 489 PIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLM 548
           PIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLM
Sbjct: 522 PIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLM 581

Query: 549 ALHHALELEYL 559
           ALHHALELEYL
Sbjct: 582 ALHHALELEYL 592


>gi|26667216 eyes absent 1 isoform b [Homo sapiens]
          Length = 592

 Score = 1122 bits (2903), Expect = 0.0
 Identities = 551/551 (100%), Positives = 551/551 (100%)

Query: 9   VKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTP 68
           VKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTP
Sbjct: 42  VKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTP 101

Query: 69  SSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQT 128
           SSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQT
Sbjct: 102 SSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQT 161

Query: 129 GFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSF 188
           GFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSF
Sbjct: 162 GFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSF 221

Query: 189 GQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIH 248
           GQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIH
Sbjct: 222 GQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIH 281

Query: 249 SPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLT 308
           SPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLT
Sbjct: 282 SPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLT 341

Query: 309 GSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLST 368
           GSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLST
Sbjct: 342 GSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLST 401

Query: 369 YNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKR 428
           YNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKR
Sbjct: 402 YNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKR 461

Query: 429 EAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVF 488
           EAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVF
Sbjct: 462 EAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVF 521

Query: 489 PIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLM 548
           PIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLM
Sbjct: 522 PIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLM 581

Query: 549 ALHHALELEYL 559
           ALHHALELEYL
Sbjct: 582 ALHHALELEYL 592


>gi|26667219 eyes absent 1 isoform c [Homo sapiens]
          Length = 557

 Score = 1029 bits (2661), Expect = 0.0
 Identities = 516/551 (93%), Positives = 516/551 (93%), Gaps = 35/551 (6%)

Query: 9   VKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTP 68
           VKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTP
Sbjct: 42  VKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTP 101

Query: 69  SSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQT 128
           SSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYG     IKTEGGLSQSQSPGQT
Sbjct: 102 SSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYG-----IKTEGGLSQSQSPGQT 156

Query: 129 GFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSF 188
           GFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSF
Sbjct: 157 GFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSF 216

Query: 189 GQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIH 248
           GQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIH
Sbjct: 217 GQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIH 276

Query: 249 SPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLT 308
           SPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLT
Sbjct: 277 SPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLT 336

Query: 309 GSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLST 368
           GSYANRYGR                              ECDQVHIDDVSSDDNGQDLST
Sbjct: 337 GSYANRYGR------------------------------ECDQVHIDDVSSDDNGQDLST 366

Query: 369 YNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKR 428
           YNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKR
Sbjct: 367 YNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKR 426

Query: 429 EAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVF 488
           EAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVF
Sbjct: 427 EAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVF 486

Query: 489 PIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLM 548
           PIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLM
Sbjct: 487 PIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLM 546

Query: 549 ALHHALELEYL 559
           ALHHALELEYL
Sbjct: 547 ALHHALELEYL 557


>gi|98991763 eyes absent 4 isoform b [Homo sapiens]
          Length = 616

 Score =  817 bits (2111), Expect = 0.0
 Identities = 416/556 (74%), Positives = 471/556 (84%), Gaps = 15/556 (2%)

Query: 7   VAVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILP 66
           +AVKTEP++SSET +TT DG+L+ F+GS I SS +SPR  HQ+SP Q+YPS +PYPHIL 
Sbjct: 73  LAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS-KPYPHILS 130

Query: 67  TPSSQTMAAY-GQTQFTTGMQQATAYATYPQPGQPYGISSY--GALWAGIKTEGGLSQSQ 123
           TP++QTM+AY GQTQ++ GMQQ   Y  Y Q GQPY + +Y  G +   IKTE GLSQ+Q
Sbjct: 131 TPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQ 189

Query: 124 SPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYP 183
           SP Q+G LSY   FSTPQPGQ PYSYQM GSSF  SS IY  NNS++NS+ F+ SQQDYP
Sbjct: 190 SPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYA-NNSVSNSTNFSGSQQDYP 248

Query: 184 SYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAE 243
           SY +FGQ QYAQYY++S Y A YMTS+NT+  TPS+ +TYQLQE   G+T+Q       E
Sbjct: 249 SYTAFGQNQYAQYYSASTYGA-YMTSNNTADGTPSSTSTYQLQESLPGLTNQP-----GE 302

Query: 244 YSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVF 303
           + T+ SPSTPIKD D +R  R S  KSRGRGR+NN PSPPPDSDLERVF+WDLDETIIVF
Sbjct: 303 FDTMQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN-PSPPPDSDLERVFVWDLDETIIVF 360

Query: 304 HSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG 363
           HSLLTGSYA +YG+DPP +V+LGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG
Sbjct: 361 HSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG 420

Query: 364 QDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLL 423
           QDLSTY+F TDGF AAA+SANLCL TGVRGGVDWMRKLAFRYRRVKE+YNTYKNNVGGLL
Sbjct: 421 QDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLL 480

Query: 424 GPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYG 483
           GPAKR+AWLQLRAEIE LTDSWLT ALK+LS+I +R+NC+N+LVTTTQLIPALAKVLLY 
Sbjct: 481 GPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYS 540

Query: 484 LGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISS 543
           LG  FPIENIYSATKIGKESCFERI+QRFGRKVVYVVIGDGVEEEQ AKKH MPFWRISS
Sbjct: 541 LGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISS 600

Query: 544 HSDLMALHHALELEYL 559
           HSDL+ALH ALELEYL
Sbjct: 601 HSDLLALHQALELEYL 616


>gi|98991760 eyes absent 4 isoform a [Homo sapiens]
          Length = 639

 Score =  817 bits (2111), Expect = 0.0
 Identities = 416/556 (74%), Positives = 471/556 (84%), Gaps = 15/556 (2%)

Query: 7   VAVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILP 66
           +AVKTEP++SSET +TT DG+L+ F+GS I SS +SPR  HQ+SP Q+YPS +PYPHIL 
Sbjct: 96  LAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS-KPYPHILS 153

Query: 67  TPSSQTMAAY-GQTQFTTGMQQATAYATYPQPGQPYGISSY--GALWAGIKTEGGLSQSQ 123
           TP++QTM+AY GQTQ++ GMQQ   Y  Y Q GQPY + +Y  G +   IKTE GLSQ+Q
Sbjct: 154 TPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQ 212

Query: 124 SPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYP 183
           SP Q+G LSY   FSTPQPGQ PYSYQM GSSF  SS IY  NNS++NS+ F+ SQQDYP
Sbjct: 213 SPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYA-NNSVSNSTNFSGSQQDYP 271

Query: 184 SYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAE 243
           SY +FGQ QYAQYY++S Y A YMTS+NT+  TPS+ +TYQLQE   G+T+Q       E
Sbjct: 272 SYTAFGQNQYAQYYSASTYGA-YMTSNNTADGTPSSTSTYQLQESLPGLTNQP-----GE 325

Query: 244 YSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVF 303
           + T+ SPSTPIKD D +R  R S  KSRGRGR+NN PSPPPDSDLERVF+WDLDETIIVF
Sbjct: 326 FDTMQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN-PSPPPDSDLERVFVWDLDETIIVF 383

Query: 304 HSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG 363
           HSLLTGSYA +YG+DPP +V+LGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG
Sbjct: 384 HSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG 443

Query: 364 QDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLL 423
           QDLSTY+F TDGF AAA+SANLCL TGVRGGVDWMRKLAFRYRRVKE+YNTYKNNVGGLL
Sbjct: 444 QDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLL 503

Query: 424 GPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYG 483
           GPAKR+AWLQLRAEIE LTDSWLT ALK+LS+I +R+NC+N+LVTTTQLIPALAKVLLY 
Sbjct: 504 GPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYS 563

Query: 484 LGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISS 543
           LG  FPIENIYSATKIGKESCFERI+QRFGRKVVYVVIGDGVEEEQ AKKH MPFWRISS
Sbjct: 564 LGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISS 623

Query: 544 HSDLMALHHALELEYL 559
           HSDL+ALH ALELEYL
Sbjct: 624 HSDLLALHQALELEYL 639


>gi|26667257 eyes absent 4 isoform d [Homo sapiens]
          Length = 639

 Score =  801 bits (2068), Expect = 0.0
 Identities = 406/556 (73%), Positives = 464/556 (83%), Gaps = 15/556 (2%)

Query: 7   VAVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILP 66
           +AVKTEP++SSET +TT DG+L+ F+GS I SS +SPR  HQ+SP Q+YPS +PYPHIL 
Sbjct: 96  LAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS-KPYPHILS 153

Query: 67  TPSSQTMAAY-GQTQFTTGMQQATAYATYPQPGQPYGISSY--GALWAGIKTEGGLSQSQ 123
           TP++QTM+AY GQTQ++ GMQQ   Y  Y Q GQPY + +Y  G +   IKTE GLSQ+Q
Sbjct: 154 TPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQ 212

Query: 124 SPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYP 183
           SP Q+G LSY   FSTPQPGQ PYSYQM GSSF  SS IY  NNS++NS+ F+ SQQDYP
Sbjct: 213 SPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYA-NNSVSNSTNFSGSQQDYP 271

Query: 184 SYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAE 243
           SY +FGQ QYAQYY++S Y A YMTS+NT+  TPS+ +TYQLQE   G+T+Q       E
Sbjct: 272 SYTAFGQNQYAQYYSASTYGA-YMTSNNTADGTPSSTSTYQLQESLPGLTNQP-----GE 325

Query: 244 YSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVF 303
           + T+ SPSTPIKD D +R  R S  KSRGRGR+NN PSPPPDSDLERVF+WDLDETIIVF
Sbjct: 326 FDTMQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN-PSPPPDSDLERVFVWDLDETIIVF 383

Query: 304 HSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG 363
           HSLLTGSYA +YG+DPP +V+LGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG
Sbjct: 384 HSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG 443

Query: 364 QDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLL 423
           QDLSTY+F TDGF AAA+SANLCL TGVRGGVDWMRKLAFRYRRVKE+YNTYKNNVGGLL
Sbjct: 444 QDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLL 503

Query: 424 GPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYG 483
           GPAKR+AWLQLRAEIE LTDSWLT ALK+LS+I +R+NC+N+LVTTTQLIPALAKVLLY 
Sbjct: 504 GPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYS 563

Query: 484 LGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISS 543
           LG  FPIENIYSATKIGKESCFERI+ RFG  + YVVIGDG +EE  A +H MPFWRISS
Sbjct: 564 LGGAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGRDEEHAANQHNMPFWRISS 623

Query: 544 HSDLMALHHALELEYL 559
           HSDL+ALH ALELEYL
Sbjct: 624 HSDLLALHQALELEYL 639


>gi|26667227 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score =  684 bits (1765), Expect = 0.0
 Identities = 340/502 (67%), Positives = 396/502 (78%), Gaps = 14/502 (2%)

Query: 58  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 117
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI SY      IKTE 
Sbjct: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYS-----IKTED 105

Query: 118 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 177
            L+ S  PGQ+GFLSYG+SFST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 106 SLNHS--PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 158

Query: 178 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 237
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 159 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 216

Query: 238 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 297
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 217 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 276

Query: 298 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 357
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 277 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 336

Query: 358 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 417
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 337 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 396

Query: 418 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 477
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 397 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 456

Query: 478 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 537
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 457 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 516

Query: 538 FWRISSHSDLMALHHALELEYL 559
           FWRIS H+DL AL HALELEYL
Sbjct: 517 FWRISCHADLEALRHALELEYL 538


>gi|26667240 eyes absent 2 isoform b [Homo sapiens]
          Length = 543

 Score =  684 bits (1765), Expect = 0.0
 Identities = 340/502 (67%), Positives = 396/502 (78%), Gaps = 14/502 (2%)

Query: 58  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 117
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI SY      IKTE 
Sbjct: 56  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYS-----IKTED 110

Query: 118 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 177
            L+ S  PGQ+GFLSYG+SFST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 111 SLNHS--PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 163

Query: 178 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 237
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 164 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 221

Query: 238 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 297
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 222 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 281

Query: 298 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 357
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 282 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 341

Query: 358 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 417
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 342 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 401

Query: 418 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 477
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 402 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 461

Query: 478 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 537
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 462 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 521

Query: 538 FWRISSHSDLMALHHALELEYL 559
           FWRIS H+DL AL HALELEYL
Sbjct: 522 FWRISCHADLEALRHALELEYL 543


>gi|26667235 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score =  684 bits (1765), Expect = 0.0
 Identities = 340/502 (67%), Positives = 396/502 (78%), Gaps = 14/502 (2%)

Query: 58  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 117
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI SY      IKTE 
Sbjct: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYS-----IKTED 105

Query: 118 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 177
            L+ S  PGQ+GFLSYG+SFST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 106 SLNHS--PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 158

Query: 178 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 237
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 159 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 216

Query: 238 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 297
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 217 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 276

Query: 298 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 357
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 277 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 336

Query: 358 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 417
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 337 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 396

Query: 418 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 477
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 397 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 456

Query: 478 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 537
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 457 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 516

Query: 538 FWRISSHSDLMALHHALELEYL 559
           FWRIS H+DL AL HALELEYL
Sbjct: 517 FWRISCHADLEALRHALELEYL 538


>gi|26667232 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score =  684 bits (1765), Expect = 0.0
 Identities = 340/502 (67%), Positives = 396/502 (78%), Gaps = 14/502 (2%)

Query: 58  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 117
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI SY      IKTE 
Sbjct: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPSYS-----IKTED 105

Query: 118 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 177
            L+ S  PGQ+GFLSYG+SFST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 106 SLNHS--PGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 158

Query: 178 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 237
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 159 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 216

Query: 238 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 297
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 217 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 276

Query: 298 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 357
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 277 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 336

Query: 358 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 417
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 337 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 396

Query: 418 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 477
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 397 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 456

Query: 478 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 537
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 457 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 516

Query: 538 FWRISSHSDLMALHHALELEYL 559
           FWRIS H+DL AL HALELEYL
Sbjct: 517 FWRISCHADLEALRHALELEYL 538


>gi|26667230 eyes absent 2 isoform c [Homo sapiens]
          Length = 514

 Score =  644 bits (1661), Expect = 0.0
 Identities = 323/502 (64%), Positives = 376/502 (74%), Gaps = 38/502 (7%)

Query: 58  NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEG 117
           +R  P +LP   S  MAAYGQTQ++ G+QQAT Y  YP P Q YGI S            
Sbjct: 51  SRSCPRVLPRQPSTAMAAYGQTQYSAGIQQATPYTAYPPPAQAYGIPS------------ 98

Query: 118 GLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS 177
                              FST   GQ+PY+YQM G++     G Y G N L N++GF S
Sbjct: 99  -------------------FSTSPTGQSPYTYQMHGTT-----GFYQGGNGLGNAAGFGS 134

Query: 178 SQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAV 237
             QDYPSYP F Q QY QYY SS Y   Y+ +S+  P+ P + +TY LQE    + +Q+ 
Sbjct: 135 VHQDYPSYPGFPQSQYPQYYGSS-YNPPYVPASSICPS-PLSTSTYVLQEASHNVPNQSS 192

Query: 238 TDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLD 297
                EY+T + PSTP K+ D+DR  R SDGK RGR +R+++PSP  D+++ERVF+WDLD
Sbjct: 193 ESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAGDNEIERVFVWDLD 252

Query: 298 ETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDV 357
           ETII+FHSLLTG++A+RYG+D  TSV +GL MEEMIFNLADTHLFFNDLE+CDQ+H+DDV
Sbjct: 253 ETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDV 312

Query: 358 SSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKN 417
           SSDDNGQDLSTYNF  DGF ++A  ANLCL +GV GGVDWMRKLAFRYRRVKE+YNTYKN
Sbjct: 313 SSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFRYRRVKEMYNTYKN 372

Query: 418 NVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALA 477
           NVGGL+G  KRE WLQLRAE+EALTD WLT +LKAL+LI+SR NCVN+LVTTTQLIPALA
Sbjct: 373 NVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALA 432

Query: 478 KVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMP 537
           KVLLYGLG VFPIENIYSATK GKESCFERI+QRFGRK VYVVIGDGVEEEQGAKKH MP
Sbjct: 433 KVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMP 492

Query: 538 FWRISSHSDLMALHHALELEYL 559
           FWRIS H+DL AL HALELEYL
Sbjct: 493 FWRISCHADLEALRHALELEYL 514


>gi|26667243 eyes absent 3 [Homo sapiens]
          Length = 573

 Score =  548 bits (1413), Expect = e-156
 Identities = 296/557 (53%), Positives = 385/557 (69%), Gaps = 20/557 (3%)

Query: 11  TEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSS 70
           + P  S +   T++  S    S   +  + + PR ++ ++  Q+Y S +PY HIL  P S
Sbjct: 29  SNPDVSDQKPETSSLASNLPMSEEIMTCTDYIPRSSNDYTS-QMY-SAKPYAHILSVPVS 86

Query: 71  QTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGF 130
           +T A  GQTQ+ T +QQ   YA YPQ  Q YG+  +GALW G+K E GL Q+ SP Q   
Sbjct: 87  ET-AYPGQTQYQT-LQQTQPYAVYPQATQTYGLPPFGALWPGMKPESGLIQTPSPSQHSV 144

Query: 131 LSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTN---SSGFNSSQQDYPSYPS 187
           L+  T  +T QP  A YSY +Q SS  T++ + + ++++ N   ++  + S QDYP+Y  
Sbjct: 145 LTCTTGLTTSQPSPAHYSYPIQASS--TNASLISTSSTIANIPAAAVASISNQDYPTYTI 202

Query: 188 FGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVT-----DPTA 242
            GQ QY   Y SS +     T+S+   TT +   TYQ ++P     + A       DP+ 
Sbjct: 203 LGQNQYQACYPSSSFGVTGQTNSDAESTTLAAT-TYQSEKPSVMAPAPAAQRLSSGDPST 261

Query: 243 EYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIV 302
             S   S +TP KD+D D+ R+    K+RG+  R  + +   DS+LERVF+WDLDETII+
Sbjct: 262 SPSL--SQTTPSKDTD-DQSRKNMTSKNRGK--RKADATSSQDSELERVFLWDLDETIII 316

Query: 303 FHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDN 362
           FHSLLTGSYA +YG+DP   +  GL MEEMIF +ADTHLFFNDLEECDQVH++DV+SDDN
Sbjct: 317 FHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDLEECDQVHVEDVASDDN 376

Query: 363 GQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGL 422
           GQDLS Y+F TDGF  +  S +   + GV+GGVDWMRKLAFRYR+V+EIY+ +K+NVGGL
Sbjct: 377 GQDLSNYSFSTDGFSGSGGSGSHGSSVGVQGGVDWMRKLAFRYRKVREIYDKHKSNVGGL 436

Query: 423 LGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLY 482
           L P ++EA  +LRAEIE LTDSWL  ALK+L LI SR NCVN+L+TTTQL+PALAKVLLY
Sbjct: 437 LSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCVNVLITTTQLVPALAKVLLY 496

Query: 483 GLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRIS 542
           GLG +FPIENIYSATKIGKESCFERI+ RFG+KV YVVIGDG +EE  AK+H MPFWRI+
Sbjct: 497 GLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRDEEIAAKQHNMPFWRIT 556

Query: 543 SHSDLMALHHALELEYL 559
           +H DL++LH ALEL++L
Sbjct: 557 NHGDLVSLHQALELDFL 573


>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
           sapiens]
          Length = 600

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 71/264 (26%), Positives = 98/264 (37%), Gaps = 29/264 (10%)

Query: 23  TADGSLNNFSGSAIGSSSFSPRPTHQFSPP-QIYPSNRPYPHILPTPSS----QTMAAYG 77
           + D S  + + +  G S+++ +PT  ++   Q Y       +  PT  S    QT A YG
Sbjct: 3   STDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYG 62

Query: 78  QTQFTTGM-QQATAYAT------YPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGF 130
           QT + T   Q  T Y T      Y QP Q YG  +Y    A + T      +QS      
Sbjct: 63  QTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQS------ 116

Query: 131 LSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQ 190
            +YGT  + P  GQ P +      S T  +     + S  N+ G  SS   Y    S+GQ
Sbjct: 117 -AYGTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSS---YGQQSSYGQ 172

Query: 191 GQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSP 250
                 Y   P P  Y   + +    PS    Y  Q    G  S    D  +        
Sbjct: 173 ---QSSYGQQP-PTSYPPQTGSYSQAPS---QYSQQSSSYGQQSSFRQDHPSSMGVYGQE 225

Query: 251 STPIKDSDSDRLRRGSDGKSRGRG 274
           S        +R   G D + RGRG
Sbjct: 226 SGGFSGPGENRSMSGPDNRGRGRG 249


>gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo
           sapiens]
          Length = 354

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 70/283 (24%), Positives = 109/283 (38%), Gaps = 36/283 (12%)

Query: 23  TADGSLNNFSGSAIGSSSFSPRPTHQFSPP-QIYPSNRPYPHILPTPSS----QTMAAYG 77
           + D S  + + +  G S+++ +PT  ++   Q Y       +  PT  S    QT A YG
Sbjct: 3   STDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYG 62

Query: 78  QTQFTTGM-QQATAYAT------YPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGF 130
           QT + T   Q  T Y T      Y QP Q YG  +Y    A + T      +QS      
Sbjct: 63  QTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQS------ 116

Query: 131 LSYGTSFSTPQPGQAPY----SYQMQGSSFTTSSGIYTGNNSLTNSS-GFNSSQQDYPSY 185
            +YGT  + P  GQ P     +    G+  T +S   +        S G+  S   YP  
Sbjct: 117 -AYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQV 175

Query: 186 PSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQE---PPSGITSQAVTDPTA 242
           P    G Y     ++P P++  TS +++  T    ++Y  Q     PS    Q+     +
Sbjct: 176 P----GSYPMQPVTAP-PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQS 230

Query: 243 EYS----TIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPS 281
            Y     T + P T        +  + S    +    R ++PS
Sbjct: 231 SYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPS 273


>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
           sapiens]
          Length = 655

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 70/283 (24%), Positives = 109/283 (38%), Gaps = 36/283 (12%)

Query: 23  TADGSLNNFSGSAIGSSSFSPRPTHQFSPP-QIYPSNRPYPHILPTPSS----QTMAAYG 77
           + D S  + + +  G S+++ +PT  ++   Q Y       +  PT  S    QT A YG
Sbjct: 3   STDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYG 62

Query: 78  QTQFTTGM-QQATAYAT------YPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGF 130
           QT + T   Q  T Y T      Y QP Q YG  +Y    A + T      +QS      
Sbjct: 63  QTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQS------ 116

Query: 131 LSYGTSFSTPQPGQAPY----SYQMQGSSFTTSSGIYTGNNSLTNSS-GFNSSQQDYPSY 185
            +YGT  + P  GQ P     +    G+  T +S   +        S G+  S   YP  
Sbjct: 117 -AYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQV 175

Query: 186 PSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQE---PPSGITSQAVTDPTA 242
           P    G Y     ++P P++  TS +++  T    ++Y  Q     PS    Q+     +
Sbjct: 176 P----GSYPMQPVTAP-PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQS 230

Query: 243 EYS----TIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPS 281
            Y     T + P T        +  + S    +    R ++PS
Sbjct: 231 SYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPS 273


>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
           sapiens]
          Length = 656

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 70/283 (24%), Positives = 109/283 (38%), Gaps = 36/283 (12%)

Query: 23  TADGSLNNFSGSAIGSSSFSPRPTHQFSPP-QIYPSNRPYPHILPTPSS----QTMAAYG 77
           + D S  + + +  G S+++ +PT  ++   Q Y       +  PT  S    QT A YG
Sbjct: 3   STDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYG 62

Query: 78  QTQFTTGM-QQATAYAT------YPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGF 130
           QT + T   Q  T Y T      Y QP Q YG  +Y    A + T      +QS      
Sbjct: 63  QTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQS------ 116

Query: 131 LSYGTSFSTPQPGQAPY----SYQMQGSSFTTSSGIYTGNNSLTNSS-GFNSSQQDYPSY 185
            +YGT  + P  GQ P     +    G+  T +S   +        S G+  S   YP  
Sbjct: 117 -AYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQV 175

Query: 186 PSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQE---PPSGITSQAVTDPTA 242
           P    G Y     ++P P++  TS +++  T    ++Y  Q     PS    Q+     +
Sbjct: 176 P----GSYPMQPVTAP-PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQS 230

Query: 243 EYS----TIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPS 281
            Y     T + P T        +  + S    +    R ++PS
Sbjct: 231 SYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPS 273


>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
           sapiens]
          Length = 661

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 70/289 (24%), Positives = 110/289 (38%), Gaps = 42/289 (14%)

Query: 23  TADGSLNNFSGSAIGSSSFSPRPTHQFSPP-QIYPSNRPYPHILPTPSS----QTMAAYG 77
           + D S  + + +  G S+++ +PT  ++   Q Y       +  PT  S    QT A YG
Sbjct: 3   STDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYG 62

Query: 78  QTQFTTGMQQ-------ATAYAT------YPQPGQPYGISSYGALWAGIKTEGGLSQSQS 124
           QT + T   Q       +T Y T      Y QP Q YG  +Y    A + T      +QS
Sbjct: 63  QTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQS 122

Query: 125 PGQTGFLSYGTSFSTPQPGQAPY----SYQMQGSSFTTSSGIYTGNNSLTNSS-GFNSSQ 179
                  +YGT  + P  GQ P     +    G+  T +S   +        S G+  S 
Sbjct: 123 -------AYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSN 175

Query: 180 QDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQE---PPSGITSQA 236
             YP  P    G Y     ++P P++  TS +++  T    ++Y  Q     PS    Q+
Sbjct: 176 YSYPQVP----GSYPMQPVTAP-PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQS 230

Query: 237 VTDPTAEYS----TIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPS 281
                + Y     T + P T        +  + S    +    R ++PS
Sbjct: 231 SYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPS 279


>gi|5454064 RNA binding motif protein 14 [Homo sapiens]
          Length = 669

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 54/196 (27%), Positives = 82/196 (41%), Gaps = 29/196 (14%)

Query: 60  PYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATY-PQPGQPYGISSYGALWAGIKTEGG 118
           PY   L +PSSQ+ AA     +      A+A ++Y  Q      ++SYGA  + + + G 
Sbjct: 284 PYRGQLASPSSQSAAASSLGPYGGAQPSASALSSYGGQAAAASSLNSYGAQGSSLASYG- 342

Query: 119 LSQSQSPGQTGFLSYG-----TSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSS 173
            +Q  S G     SYG     +S++T     +  SY  Q +S+        G  S  +S 
Sbjct: 343 -NQPSSYGAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASY--------GAQSAASSL 393

Query: 174 GFNSSQQDYPSYPSFGQGQYAQY-YNSSPYPAHYMTSSNTSPTT----PSTNATYQLQEP 228
            + +    Y + PS      A Y   S+PY A    S ++ P      P+T A Y  Q  
Sbjct: 394 AYGAQAASYNAQPS------ASYNAQSAPYAAQQAASYSSQPAAYVAQPATAAAYASQ-- 445

Query: 229 PSGITSQAVTDPTAEY 244
           P+   +QA T     Y
Sbjct: 446 PAAYAAQATTPMAGSY 461


>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
           [Homo sapiens]
          Length = 526

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 57/198 (28%), Positives = 75/198 (37%), Gaps = 35/198 (17%)

Query: 86  QQAT-AYATYP-QPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPG 143
           QQAT +Y  YP QPGQ Y   S                SQ  GQ  +  Y  S  T   G
Sbjct: 8   QQATQSYGAYPTQPGQGYSQQS----------------SQPYGQQSYSGYSQSTDTSGYG 51

Query: 144 QAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQY--YNSSP 201
           Q+  SY   G S  T  G  +      ++ G+ SSQ    SY     GQ + Y  Y   P
Sbjct: 52  QS--SYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSY-----GQQSSYPGYGQQP 104

Query: 202 YPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQ--AVTDPTAEYSTIHSPSTPIKDSDS 259
            P      S+TS +  S++ +    +P SG  SQ  +       Y    S + P      
Sbjct: 105 AP------SSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQ 158

Query: 260 DRLRRGSDGKSRGRGRRN 277
           ++    S G   G G  N
Sbjct: 159 NQYNSSSGGGGGGGGGGN 176


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo
           sapiens]
          Length = 1758

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 47/177 (26%), Positives = 76/177 (42%), Gaps = 22/177 (12%)

Query: 51  PPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALW 110
           PP +YP   P PH LP P       +   QF  G      Y+  P PG P   ++    W
Sbjct: 561 PPPLYP---PPPHTLPLPPGVPPPQFSP-QFPPGQPPPAGYSV-PPPGFPPAPANLSTPW 615

Query: 111 --AGIKT--EGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGN 166
             +G++T     +  +Q+P  +    Y       +  ++PYS    GSS++ SS  Y+ +
Sbjct: 616 VSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEESKSPYS----GSSYSRSSYTYSKS 671

Query: 167 NS-LTNSSGFNSS-----QQDY---PSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSP 214
            S  T S  ++ S      + Y   P YP  G+G+   Y + S    ++ + S + P
Sbjct: 672 RSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPP 728


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 64/273 (23%), Positives = 103/273 (37%), Gaps = 35/273 (12%)

Query: 8    AVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPP----------QIYPS 57
            A  TE    ++T+   + GS    +G+A  SSS +   T   S               PS
Sbjct: 776  AESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPS 835

Query: 58   NRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATY-------PQPGQPYGISSYGALW 110
               +     T      A++G    +TGM  +    T+          G+P G SS     
Sbjct: 836  RDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSS----- 890

Query: 111  AGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLT 170
                     S S SP +T  +S        +  +   +  +   +  T S +     S+T
Sbjct: 891  -------PTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSIT 943

Query: 171  NSSGFNSSQQDYPSYPSFGQGQY---AQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQE 227
             S+G  S Q +  +    G G+    A   N++P P  Y +S++T  TTP  + T     
Sbjct: 944  -STGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTP-LHVTDASSV 1001

Query: 228  PPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSD 260
                 T   VT P++  ST H+   P+ D+ S+
Sbjct: 1002 STGHATPLPVTSPSS-VSTGHTTPLPVTDTSSE 1033



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 49/257 (19%), Positives = 103/257 (40%), Gaps = 20/257 (7%)

Query: 3   LFPQVAVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYP 62
           +F     +   + ++E  S +  G+++  + S + +  +S   +   SP  + P      
Sbjct: 393 VFRMPTSRDSTLGNTEETSLSVSGTISAIT-SKVSTIWWSDTLSTALSPSSLPPKISTAF 451

Query: 63  HILPTPSSQTMAA-YGQTQFTTGMQQATAYATYPQPGQPYGISSYG-ALWAGIKTEGGLS 120
           H   +  ++T    + ++ F+ G+ Q   +  +     P   SS G   W+  +     +
Sbjct: 452 HTQQSEGAETTGRPHERSSFSPGVSQEI-FTLHETTTWPSSFSSKGHTTWSQTELPSTST 510

Query: 121 QSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQ 180
            + +   TG  S GT+ + P+      +    G   T SS     + +L  ++G  +  Q
Sbjct: 511 GAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSH----STTLPKTTGAGAQTQ 566

Query: 181 DYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDP 240
                 + G+   +        P++ +T    + T+PS++            + Q  T P
Sbjct: 567 WTQETGTTGEALLSS-------PSYSVTQMIKTATSPSSSPMLDRHT-----SQQITTAP 614

Query: 241 TAEYSTIHSPSTPIKDS 257
           +  +STIHS ST  ++S
Sbjct: 615 STNHSTIHSTSTSPQES 631



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 58/274 (21%), Positives = 104/274 (37%), Gaps = 54/274 (19%)

Query: 13   PMSSSETASTTADGSLNNFSGSAIGSSSFSPRPT---------HQFSPPQIYPSNRPYPH 63
            P++   +AST     L   S S+  +   +P P          H  S P    S+    H
Sbjct: 3794 PVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGH 3853

Query: 64   ILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQ 123
              P P + T +             +T +AT      P  ++S  ++  G  T   ++   
Sbjct: 3854 ATPLPVTDTSSV------------STGHAT------PLPVTSTSSVSTGHATPLPVTSPS 3895

Query: 124  SPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSS---FTTSSGIYTGNNSLTNSSGFNSSQQ 180
            S          T  +TP P  +  S     ++    T +S + TG+ +  + +  +S+ +
Sbjct: 3896 SAS--------TGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASR 3947

Query: 181  DYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTP----STNATYQLQEPPSGITSQA 236
               S         A   +++P P   ++S +T  TTP     T++    Q  P  +TS +
Sbjct: 3948 GDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLS 4007

Query: 237  -----------VTDPTAEYSTIHSPSTPIKDSDS 259
                       VT P++  S+ H+ S P+ D+ S
Sbjct: 4008 SVSTGDTTPLPVTIPSSA-SSGHTTSLPVTDASS 4040


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 59/248 (23%), Positives = 90/248 (36%), Gaps = 20/248 (8%)

Query: 16   SSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYP-SNRPYPHILPTPSSQTMA 74
            S    S    G+      +A  +S FSP  +  +SP    P S  P    +P+P      
Sbjct: 1532 SPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSP 1591

Query: 75   AYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTE-GGLSQSQSPGQTGFLSY 133
            +Y  T        + AY    +P  P G +     ++         S S SP    +   
Sbjct: 1592 SYSPT--------SPAY----EPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPT 1639

Query: 134  GTSFSTPQPGQAPYS--YQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQG 191
              S+S   P  +P S  Y     S++ +S  Y    S T+ S   +S    P+ PS+   
Sbjct: 1640 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY----SPTSPSYSPTSPSYSPTSPSYSPT 1695

Query: 192  QYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPS 251
              +    S  Y     + S TSP+   T+ +Y    P    TS + +  +  YS      
Sbjct: 1696 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNY 1755

Query: 252  TPIKDSDS 259
            TP   S S
Sbjct: 1756 TPTSPSYS 1763



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 65/276 (23%), Positives = 100/276 (36%), Gaps = 33/276 (11%)

Query: 38   SSSFSPR-PTHQFSPPQIYPSNRPYPHILPT--PSSQTMAAYGQTQFTTGMQQATAYATY 94
            S S+SP  P++  + P   P++  Y    P+  P+S + +        T         +Y
Sbjct: 1703 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSY 1762

Query: 95   PQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYS--YQMQ 152
                  Y  +S              S + SP    +     S+S   P  +P S  Y  Q
Sbjct: 1763 SPTSPSYSPTS--------PNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQ 1814

Query: 153  GSSFTTSSGIYTGNN---SLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPY-----PA 204
              ++T SS  Y+ ++   S T+     +S    PS P +      +Y  +SP      P 
Sbjct: 1815 SPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTS-PKYSPTSPKYSPTSPK 1873

Query: 205  HYMTSSNTSPTTPS---TNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDR 261
            +  TS   SPTTP    T+ TY    P    TS   +  +  YS      +P   + S  
Sbjct: 1874 YSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPT 1933

Query: 262  LRRGSDGKSRGRGRRNNNPS--------PPPDSDLE 289
              +GS       G    +P+         P DSD E
Sbjct: 1934 SPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEE 1969



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 54/229 (23%), Positives = 82/229 (35%), Gaps = 21/229 (9%)

Query: 33   GSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILP---TPSSQTMAAYGQTQFTTGMQQAT 89
            GS   SS + P P    SP    P++  Y    P   TP S + +    +   T    + 
Sbjct: 1573 GSPGPSSPYIPSPGGAMSP-SYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSP 1631

Query: 90   AYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYS- 148
                Y      Y  +S         +    S S SP    +     S+S   P  +P S 
Sbjct: 1632 TSPNYSPTSPSYSPTS--------PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1683

Query: 149  -YQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYM 207
             Y     S++ +S  Y    S T+ S   +S    P+ PS+     +    S  Y     
Sbjct: 1684 SYSPTSPSYSPTSPSY----SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1739

Query: 208  TSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEY---STIHSPSTP 253
            + S TSP    T+  Y    P    TS + +  +  Y   S  +SP++P
Sbjct: 1740 SYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSP 1788


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 55/255 (21%), Positives = 105/255 (41%), Gaps = 4/255 (1%)

Query: 15  SSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMA 74
           ++S ++ T++  S    SGS++ S+  S     +F       S           S  ++A
Sbjct: 46  TNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIA 105

Query: 75  AYGQTQFTT-GMQQAT-AYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLS 132
              ++  T+ G   AT + ++ P  G     +S  +  +   +    S S +       +
Sbjct: 106 TNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTA 165

Query: 133 YGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQ 192
             +  ST   G A  +   + S+ ++ +   T + S T SSG +++        S G G 
Sbjct: 166 TNSESSTTSSG-ASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGT 224

Query: 193 YAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPST 252
            A    SS   +   T++N+  +TPS+ A        S  +S A T   +E ST+ S  +
Sbjct: 225 -ATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGIS 283

Query: 253 PIKDSDSDRLRRGSD 267
            + +S+S     G++
Sbjct: 284 TVTNSESSTPSSGAN 298



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 60/283 (21%), Positives = 110/283 (38%), Gaps = 8/283 (2%)

Query: 14  MSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTM 73
           ++++  +STT+ G+    +  +   SS +   T+  S      ++        T SS+  
Sbjct: 104 IATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEAS 163

Query: 74  AAYGQTQFTTGMQQATAY----ATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTG 129
            A      TT    +TA     +T          S      +G  T    S+S++     
Sbjct: 164 TATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATN-SESRTTSNGA 222

Query: 130 FLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFG 189
             +  +  ST   G A  +   + S+ ++ +G  T + S T SSG  ++     S  S G
Sbjct: 223 GTATNSESSTTSSG-ASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSG 281

Query: 190 QGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHS 249
                   +S+P  +   T++N+  +T S+ A        S  +S A T   +E ST  S
Sbjct: 282 ISTVTNSESSTP-SSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSS 340

Query: 250 PSTPIKDSDSDRLRRG-SDGKSRGRGRRNNNPSPPPDSDLERV 291
            ++   +S+S     G S   + G    ++  S   +S+   V
Sbjct: 341 GASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTV 383



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 45/196 (22%), Positives = 68/196 (34%), Gaps = 16/196 (8%)

Query: 15  SSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMA 74
           ++SE+++T++       S S+  SS  S     + S P    +         T S    A
Sbjct: 256 TNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTA 315

Query: 75  --------AYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWA---GIKTEGGLSQSQ 123
                   + G +  T      T+             +S GA  A   G  T    + + 
Sbjct: 316 TNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTA 375

Query: 124 SPGQTGFLSYGTSFSTPQPGQAPYS---YQMQGSSFTTSSGIYTGNNS--LTNSSGFNSS 178
           +  ++  +S G S +T        S         S T SSG  T  NS   T SSG N++
Sbjct: 376 TNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTA 435

Query: 179 QQDYPSYPSFGQGQYA 194
                S  S G G  A
Sbjct: 436 TNSGSSVTSAGSGTAA 451


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 67/240 (27%), Positives = 93/240 (38%), Gaps = 53/240 (22%)

Query: 14   MSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTM 73
            +++S T+ T +  S    S S I SSS+ P+  +  S P   P     PH+    SS T 
Sbjct: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQ--NSSSRPPSSPITTQLPHL----SSAT- 2118

Query: 74   AAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSY 133
                 T  +T  Q +++++  P P  P  +SSY            +  S S  QT   S 
Sbjct: 2119 -----TPVSTTNQLSSSFS--PSPSAPSTVSSY------------VPSSHSSPQTSSPSV 2159

Query: 134  GTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQY 193
            GTS                      SS +    +S T SSG +SS   +P+  S      
Sbjct: 2160 GTS----------------------SSFVSAPVHSTTLSSGSHSSLSTHPTTASVSA--- 2194

Query: 194  AQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTP 253
            +  + SS  PA   T   T P T S+  T     P S +T           STI  PSTP
Sbjct: 2195 SPLFPSS--PAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTP 2252



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 60/257 (23%), Positives = 92/257 (35%), Gaps = 21/257 (8%)

Query: 11   TEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSS 70
            T P  ++   S T   S N        + +  PRPT   +     P  +P     PT ++
Sbjct: 1330 TLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTP--QPGQPTRPT-AT 1386

Query: 71   QTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWA----GIKTEGGLSQSQSPG 126
            +T      T++TT     T ++  P  G P  + S G + A       T    S  ++  
Sbjct: 1387 ETTQTRTTTEYTTPQTPHTTHSP-PTAGSP--VPSTGPVTATSFHATTTYPTPSHPETTL 1443

Query: 127  QTGFLSYGTSFSTPQPGQA--PYSYQM--QGSSFTTSSGIYTGNNSLTNSSGFNSSQQDY 182
             T    + TS  TP       P   QM    S+ +  +G      +L  +   +++    
Sbjct: 1444 PTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPIT 1503

Query: 183  PSYPSFGQGQYAQYYNSSPYPAHYMTSSN-------TSPTTPSTNATYQLQEPPSGITSQ 235
            P+     Q   +   N +P   H  TSS        TS TT + N T      P   T+ 
Sbjct: 1504 PTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNS 1563

Query: 236  AVTDPTAEYSTIHSPST 252
            A +       T HSP T
Sbjct: 1564 ATSSRPPPPFTTHSPPT 1580



 Score = 36.6 bits (83), Expect = 0.062
 Identities = 58/253 (22%), Positives = 93/253 (36%), Gaps = 24/253 (9%)

Query: 5    PQVAVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSN-RPYPH 63
            P     + P  SS  +ST         + ++  +++  P P+H   P    P++  P+  
Sbjct: 1571 PPFTTHSPPTGSSPFSST------GPMTATSFKTTTTYPTPSH---PQTTLPTHVPPFST 1621

Query: 64   ILPTPSSQTMAAYGQTQFTTGMQ-QATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQS 122
             L TPS+ T+      Q  T     +    T P P       S         T  G SQ+
Sbjct: 1622 SLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQA 1681

Query: 123  QSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFT--TSSGIYTGNNSLT-NSSGFNSSQ 179
             S   T      TS S      + +  +   +S T  T +   TG   +T  +SG + S+
Sbjct: 1682 LSSLNTA----KTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSR 1737

Query: 180  QDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTD 239
                   SF   + +   +S     H+   ++TS T+ + N T      P   T+ A + 
Sbjct: 1738 S------SFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSS 1791

Query: 240  PTAEYSTIHSPST 252
                  T HSP T
Sbjct: 1792 RLPTPFTTHSPPT 1804


>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
          Length = 2603

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 61/264 (23%), Positives = 100/264 (37%), Gaps = 33/264 (12%)

Query: 14   MSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNR-----PYPHILPTP 68
            + SS   +T A+ SL     + +  SS S   T    P     S       P  ++ P  
Sbjct: 1818 IGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNPVNNVRPGF 1877

Query: 69   SSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQT 128
                  AY   QF   +  A  +     P  P  ++ +G  +   ++  G      P   
Sbjct: 1878 PVSLPLAYPPPQFAHALLAAQTFQQIRPPRLP--MTHFGGTFPPAQSTWG------PFPV 1929

Query: 129  GFLSYGTSFSTPQPGQAP-YSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS----SQQDYP 183
              LS   + ++P+P   P +S Q    S   S+G  T + + T SS  ++    S    P
Sbjct: 1930 RPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSP 1989

Query: 184  SYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTA- 242
            S PS  +  +     +S      +T++ ++  T  TNATY +              PTA 
Sbjct: 1990 SSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPM--------------PTAK 2035

Query: 243  EYSTIHSPSTPIKDSDSDRLRRGS 266
            E+  + SPS+P   +    + R S
Sbjct: 2036 EHYPVSSPSSPSPPAQPGGVSRNS 2059


>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
          Length = 2352

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 61/264 (23%), Positives = 100/264 (37%), Gaps = 33/264 (12%)

Query: 14   MSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNR-----PYPHILPTP 68
            + SS   +T A+ SL     + +  SS S   T    P     S       P  ++ P  
Sbjct: 1567 IGSSAPTTTAANTSLMGIKMTTVALSSTSQTATALTVPAISSASTHKTIKNPVNNVRPGF 1626

Query: 69   SSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQT 128
                  AY   QF   +  A  +     P  P  ++ +G  +   ++  G      P   
Sbjct: 1627 PVSLPLAYPPPQFAHALLAAQTFQQIRPPRLP--MTHFGGTFPPAQSTWG------PFPV 1678

Query: 129  GFLSYGTSFSTPQPGQAP-YSYQMQGSSFTTSSGIYTGNNSLTNSSGFNS----SQQDYP 183
              LS   + ++P+P   P +S Q    S   S+G  T + + T SS  ++    S    P
Sbjct: 1679 RPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTSTNGSP 1738

Query: 184  SYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTA- 242
            S PS  +  +     +S      +T++ ++  T  TNATY +              PTA 
Sbjct: 1739 SSPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNATYPM--------------PTAK 1784

Query: 243  EYSTIHSPSTPIKDSDSDRLRRGS 266
            E+  + SPS+P   +    + R S
Sbjct: 1785 EHYPVSSPSSPSPPAQPGGVSRNS 1808


>gi|54607108 zinc finger, MIZ-type containing 2 isoform 1 [Homo
           sapiens]
          Length = 920

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 65/248 (26%), Positives = 90/248 (36%), Gaps = 58/248 (23%)

Query: 33  GSAIGSSSFSP---RPTHQFSPPQIYPSNRPYPHILP-TPSSQTMA----------AYGQ 78
           G  +G S  SP    PT       +Y   R   H  P  P +Q +            Y  
Sbjct: 216 GGVMGPSGLSPLAMNPTRAAGMTPLYAGQRLPQHGYPGPPQAQPLPRQGVKRTYSEVYPG 275

Query: 79  TQFTTGMQQATAYATY-PQPGQPYGIS-SYGALWAGIKTEGGLSQSQS-PGQTGFLSYGT 135
            Q+  G Q A + A + P PGQP   S SY      +  + G++QS S PG TG     T
Sbjct: 276 QQYLQGGQYAPSTAQFAPSPGQPPAPSPSYPG--HRLPLQQGMTQSLSVPGPTGLHYKPT 333

Query: 136 SFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQ 195
                        +  QG+SF   S  Y+         G +   +  P YPS        
Sbjct: 334 E-----------QFNGQGASFNGGSVSYS-------QPGLSGPTRSIPGYPS-------- 367

Query: 196 YYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIK 255
               SP P +      T P TPS++  Y    P   + S  + D     +++H  S+P  
Sbjct: 368 ----SPLPGN-----PTPPMTPSSSVPY--MSPNQEVKSPFLPDLKPNLNSLH--SSPSG 414

Query: 256 DSDSDRLR 263
               D LR
Sbjct: 415 SGPCDELR 422


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 67/294 (22%), Positives = 111/294 (37%), Gaps = 32/294 (10%)

Query: 15   SSSETASTTADGSLNNFSGSAIGSSSF------SPRPTHQFSPPQIY-PSNRPYPH--IL 65
            S   +  T A G L++    A G++        +P  + QFS P  + PS   +    I 
Sbjct: 1171 SLKPSGPTPASGQLSS-GDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT 1229

Query: 66   PTPSSQTMAAYGQT----------QFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKT 115
            PTPSS   AA G T           F++G     +Y   P+   P GI+S      G + 
Sbjct: 1230 PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPG-EP 1288

Query: 116  EGGLSQSQSPGQTGFLSYGTSFSTP--QPGQAPYSYQMQGSSFTTSSGIYTGN-NSLTNS 172
                S+  +P  T   +  +   TP  + G+  +   + G +  + SG+  G  +  T  
Sbjct: 1289 AASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKP 1348

Query: 173  SGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGI 232
            +   SS     + P+   G  + +  ++P     +   +T P  P T++       P   
Sbjct: 1349 TNKASSTSLTSTQPTKTSGVPSGFNFTAP----PVLGKHTEP--PVTSSATTTSVAPPAA 1402

Query: 233  TSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNN--PSPPP 284
            TS + T          + S+ +       L  G    S G  + N+   PS PP
Sbjct: 1403 TSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPP 1456



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 53/201 (26%), Positives = 83/201 (41%), Gaps = 19/201 (9%)

Query: 7    VAVKTE--PMSSSETASTTADGSLNN--FSGSAIGSSSFSPRPTHQFSPP--QIYPSNRP 60
            VAV+T   P++SS T+      S     F     GSS F+  P    S    Q+  +   
Sbjct: 1607 VAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTAT 1666

Query: 61   YPHILPT----PSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTE 116
             P   P      +S   + +GQ    TG   +TA AT       +   ++G    G+  +
Sbjct: 1667 APSATPVFGQVAASTAPSLFGQQ---TGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQ 1723

Query: 117  GGLSQSQSPGQTGFLSYGT-SFSTPQPGQAPYSYQMQGSSFTTSSG-IYTGNNSLTNSSG 174
                Q+   GQ+   +    SFS P     P   Q   S+ T++SG ++   +S ++SS 
Sbjct: 1724 TTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSS 1783

Query: 175  FNSSQQDYPSYPSFGQGQYAQ 195
            F+  Q    S P+ G G + Q
Sbjct: 1784 FSFGQ----SSPNTGGGLFGQ 1800



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 55/222 (24%), Positives = 80/222 (36%), Gaps = 35/222 (15%)

Query: 15  SSSETASTTADGSLNNFSGSAIGSSSFSPRP---THQFSPPQIYPSNRPYPHILPTPSSQ 71
           SSS  +S T  G   ++S S   SS  +P P   T  F PP    S  P P   P   S 
Sbjct: 486 SSSLKSSATVTGEPPSYS-SGSDSSKAAPGPGPSTFSFVPPS-KASLAPTPAASPVAPSA 543

Query: 72  TMAAYGQTQF-----TTGMQQATAYATYPQPGQPYGIS----SYGALWAGIKTEGGLSQS 122
              ++G + F     +T +   +A     +P  P   S    +    +    T   +S S
Sbjct: 544 ASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSS 603

Query: 123 QS------------PGQTGFLSYGTSFSTPQPG--------QAPYSYQMQGSSFTTSSGI 162
           QS            P  +G LS+ T  S P            +P     QGSS    S +
Sbjct: 604 QSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVPSMV 663

Query: 163 YTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPA 204
              +  +T  +    S Q     P+  + Q  Q+ +S P  A
Sbjct: 664 QK-SPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDPVMA 704


>gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo
           sapiens]
          Length = 598

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 48/174 (27%), Positives = 71/174 (40%), Gaps = 23/174 (13%)

Query: 21  STTADGSLNNFSGSAIGSSSFSPRP-THQFSPPQIYPSNRPYPHILPTPSSQTMAAY-GQ 78
           S   D +L++      GS   +P P T  F PPQ+ P +  + H  P+ + + + A+  Q
Sbjct: 117 SGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQ 176

Query: 79  TQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFS 138
               +G  Q  A+ ++  P  P    +   L         L  SQ+  Q G    G S+S
Sbjct: 177 LPKASGPPQPPAFFSFSPPTGPSPSLAQSPL--------KLFPSQATHQLG---EGESYS 225

Query: 139 TPQ--PGQAPYSYQMQGS--------SFTTSSGIYTGNNSLTNSSGFNSSQQDY 182
            P   PG AP S  ++GS        S    SG   G+       G N+S Q Y
Sbjct: 226 MPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHY 279


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,640,693
Number of Sequences: 37866
Number of extensions: 1211288
Number of successful extensions: 5066
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 230
Number of HSP's that attempted gapping in prelim test: 4382
Number of HSP's gapped (non-prelim): 772
length of query: 559
length of database: 18,247,518
effective HSP length: 107
effective length of query: 452
effective length of database: 14,195,856
effective search space: 6416526912
effective search space used: 6416526912
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press