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Search of human proteins with 26638655
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|26638655 potassium voltage-gated channel KQT-like protein 4
isoform b [Homo sapiens]
(641 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|26638655 potassium voltage-gated channel KQT-like protein 4 i... 1282 0.0
gi|26638653 potassium voltage-gated channel KQT-like protein 4 i... 1233 0.0
gi|236461719 potassium voltage-gated channel, KQT-like subfamily... 762 0.0
gi|28373065 potassium voltage-gated channel, KQT-like subfamily,... 760 0.0
gi|236461942 potassium voltage-gated channel, KQT-like subfamily... 754 0.0
gi|236462079 potassium voltage-gated channel, KQT-like subfamily... 751 0.0
gi|26051260 potassium voltage-gated channel KQT-like protein 2 i... 665 0.0
gi|26051266 potassium voltage-gated channel KQT-like protein 2 i... 662 0.0
gi|26051262 potassium voltage-gated channel KQT-like protein 2 i... 661 0.0
gi|26051264 potassium voltage-gated channel KQT-like protein 2 i... 648 0.0
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H... 571 e-163
gi|236462242 potassium voltage-gated channel, KQT-like subfamily... 510 e-144
gi|26051268 potassium voltage-gated channel KQT-like protein 2 i... 482 e-136
gi|32479527 potassium voltage-gated channel, KQT-like subfamily,... 413 e-115
gi|32479525 potassium voltage-gated channel, KQT-like subfamily,... 379 e-105
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 104 3e-22
gi|27436974 potassium voltage-gated channel, Shab-related subfam... 99 9e-21
gi|21217561 Shaw-related voltage-gated potassium channel protein... 91 3e-18
gi|21217563 Shaw-related voltage-gated potassium channel protein... 91 3e-18
gi|24497458 Shaw-related voltage-gated potassium channel protein... 91 3e-18
gi|88758576 Shaw-related voltage-gated potassium channel protein... 91 4e-18
gi|24497462 Shaw-related voltage-gated potassium channel protein... 91 4e-18
gi|24497464 Shaw-related voltage-gated potassium channel protein... 91 4e-18
gi|6912444 potassium voltage-gated channel, subfamily G, member ... 90 6e-18
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 88 2e-17
gi|27436986 potassium voltage-gated channel, Shal-related subfam... 88 2e-17
gi|88758565 potassium voltage-gated channel, shaker-related subf... 87 4e-17
gi|119395748 potassium voltage-gated channel subfamily A member ... 87 6e-17
gi|20070166 potassium voltage-gated channel, subfamily F, member... 86 8e-17
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 86 1e-16
>gi|26638655 potassium voltage-gated channel KQT-like protein 4
isoform b [Homo sapiens]
Length = 641
Score = 1282 bits (3317), Expect = 0.0
Identities = 641/641 (100%), Positives = 641/641 (100%)
Query: 1 MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG 60
MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG
Sbjct: 1 MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG 60
Query: 61 PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST 120
PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST
Sbjct: 61 PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST 120
Query: 121 IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI 180
IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI
Sbjct: 121 IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI 180
Query: 181 VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT 240
VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT
Sbjct: 181 VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT 240
Query: 241 AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA 300
AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA
Sbjct: 241 AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA 300
Query: 301 AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA 360
AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA
Sbjct: 301 AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA 360
Query: 361 YLTATWYYYDSILPSFSSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEAT 420
YLTATWYYYDSILPSFSSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEAT
Sbjct: 361 YLTATWYYYDSILPSFSSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEAT 420
Query: 421 SPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVI 480
SPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVI
Sbjct: 421 SPTKVQKSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVI 480
Query: 481 RSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDR 540
RSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDR
Sbjct: 481 RSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDR 540
Query: 541 KAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGA 600
KAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGA
Sbjct: 541 KAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGA 600
Query: 601 VQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD 641
VQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD
Sbjct: 601 VQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD 641
>gi|26638653 potassium voltage-gated channel KQT-like protein 4
isoform a [Homo sapiens]
Length = 695
Score = 1233 bits (3189), Expect = 0.0
Identities = 631/695 (90%), Positives = 634/695 (91%), Gaps = 54/695 (7%)
Query: 1 MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG 60
MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG
Sbjct: 1 MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG 60
Query: 61 PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST 120
PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST
Sbjct: 61 PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST 120
Query: 121 IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI 180
IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI
Sbjct: 121 IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI 180
Query: 181 VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT 240
VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT
Sbjct: 181 VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT 240
Query: 241 AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA 300
AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA
Sbjct: 241 AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA 300
Query: 301 AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA 360
AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA
Sbjct: 301 AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA 360
Query: 361 YLTATWYYYDSILPSFSSRMGIKDRI---------------------------------- 386
YLTATWYYYDSILPSF + + +
Sbjct: 361 YLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHR 420
Query: 387 ------------RMG--------SSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ 426
RMG SSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ
Sbjct: 421 PGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ 480
Query: 427 KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL 486
KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL
Sbjct: 481 KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL 540
Query: 487 KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG 546
KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG
Sbjct: 541 KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG 600
Query: 547 DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF 606
DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF
Sbjct: 601 DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF 660
Query: 607 DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD 641
DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD
Sbjct: 661 DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD 695
>gi|236461719 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 2 [Homo sapiens]
Length = 923
Score = 762 bits (1967), Expect = 0.0
Identities = 408/627 (65%), Positives = 484/627 (77%), Gaps = 44/627 (7%)
Query: 37 GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87
GGGG R R+ LLG PL S +S + +YRR+QN++
Sbjct: 70 GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115
Query: 88 YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147
YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+
Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175
Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207
I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R
Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235
Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267
FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F
Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295
Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327
S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ
Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355
Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFS---SRMGIKD 384
EQHRQKHFEKRR PAANLIQ WR Y+ D ++ ATW + L + S ++ K+
Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATWKPHLKALHTCSPTNQKLSFKE 414
Query: 385 RIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRL- 443
R+RM S + ++ S+Q A SPS++ E SPTKVQKSWSFNDRTRFR SLRL
Sbjct: 415 RVRMASPRGQSIKSRQ--ASVGDRRSPSTDITAEG-SPTKVQKSWSFNDRTRFRPSLRLK 471
Query: 444 ----KPRTSAEDA-PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKET 498
KP A+ A +++V +EK QC+++V+D+ P +KTVIR+IRI+KF VAKRKFKET
Sbjct: 472 SSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKET 531
Query: 499 LRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGDRKAREKGDKGPSDAEVV 556
LRPYDVKDVIEQYSAGHLDML RIKSLQTRVDQI+G+G D+K+RE K ++ E
Sbjct: 532 LRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSRE---KITAEHETT 588
Query: 557 DEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--SLGAVQVPLFDPDITSDY 614
D++SM+GRVVKVEKQVQSIE KLD LL Y + LR G+++ +L + Q+P F+ + TSDY
Sbjct: 589 DDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDY 648
Query: 615 HSPVDHEDISVSAQTLS-ISRSVSTNM 640
SPVD +D+S SAQ +SRS S N+
Sbjct: 649 QSPVDSKDLSGSAQNSGCLSRSTSANI 675
>gi|28373065 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 1 [Homo sapiens]
Length = 932
Score = 760 bits (1962), Expect = 0.0
Identities = 409/636 (64%), Positives = 484/636 (76%), Gaps = 53/636 (8%)
Query: 37 GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87
GGGG R R+ LLG PL S +S + +YRR+QN++
Sbjct: 70 GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115
Query: 88 YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147
YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+
Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175
Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207
I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R
Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235
Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267
FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F
Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295
Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327
S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ
Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355
Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSIL------------PS 375
EQHRQKHFEKRR PAANLIQ WR Y+ D ++ ATW + L S
Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATWKPHLKALHTCSPTKKEQGEAS 414
Query: 376 FSSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRT 435
S ++ K+R+RM S + ++ S+Q A SPS++ E SPTKVQKSWSFNDRT
Sbjct: 415 SSQKLSFKERVRMASPRGQSIKSRQ--ASVGDRRSPSTDITAEG-SPTKVQKSWSFNDRT 471
Query: 436 RFRASLRL-----KPRTSAEDA-PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFL 489
RFR SLRL KP A+ A +++V +EK QC+++V+D+ P +KTVIR+IRI+KF
Sbjct: 472 RFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFH 531
Query: 490 VAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGDRKAREKGD 547
VAKRKFKETLRPYDVKDVIEQYSAGHLDML RIKSLQTRVDQI+G+G D+K+RE
Sbjct: 532 VAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSRE--- 588
Query: 548 KGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--SLGAVQVPL 605
K ++ E D++SM+GRVVKVEKQVQSIE KLD LL Y + LR G+++ +L + Q+P
Sbjct: 589 KITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPP 648
Query: 606 FDPDITSDYHSPVDHEDISVSAQTLS-ISRSVSTNM 640
F+ + TSDY SPVD +D+S SAQ +SRS S N+
Sbjct: 649 FECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANI 684
>gi|236461942 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 3 [Homo sapiens]
Length = 942
Score = 754 bits (1948), Expect = 0.0
Identities = 408/646 (63%), Positives = 484/646 (74%), Gaps = 63/646 (9%)
Query: 37 GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87
GGGG R R+ LLG PL S +S + +YRR+QN++
Sbjct: 70 GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115
Query: 88 YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147
YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+
Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175
Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207
I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R
Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235
Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267
FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F
Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295
Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327
S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ
Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355
Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSF----------- 376
EQHRQKHFEKRR PAANLIQ WR Y+ D ++ ATW + L +
Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATWKPHLKALHTCSPTNKFCSNKQ 414
Query: 377 -----------SSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKV 425
S ++ K+R+RM S + ++ S+Q A SPS++ E SPTKV
Sbjct: 415 KLFRMYTSRKQSQKLSFKERVRMASPRGQSIKSRQ--ASVGDRRSPSTDITAEG-SPTKV 471
Query: 426 QKSWSFNDRTRFRASLRL-----KPRTSAEDA-PSEEVAEEKSYQCELTVDDIMPAVKTV 479
QKSWSFNDRTRFR SLRL KP A+ A +++V +EK QC+++V+D+ P +KTV
Sbjct: 472 QKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTV 531
Query: 480 IRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRG--P 537
IR+IRI+KF VAKRKFKETLRPYDVKDVIEQYSAGHLDML RIKSLQTRVDQI+G+G
Sbjct: 532 IRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIT 591
Query: 538 GDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA- 596
D+K+RE K ++ E D++SM+GRVVKVEKQVQSIE KLD LL Y + LR G+++
Sbjct: 592 SDKKSRE---KITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASA 648
Query: 597 -SLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLS-ISRSVSTNM 640
+L + Q+P F+ + TSDY SPVD +D+S SAQ +SRS S N+
Sbjct: 649 LALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANI 694
>gi|236462079 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 4 [Homo sapiens]
Length = 951
Score = 751 bits (1939), Expect = 0.0
Identities = 408/655 (62%), Positives = 484/655 (73%), Gaps = 72/655 (10%)
Query: 37 GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87
GGGG R R+ LLG PL S +S + +YRR+QN++
Sbjct: 70 GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115
Query: 88 YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147
YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+
Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175
Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207
I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R
Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235
Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267
FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F
Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295
Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327
S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ
Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355
Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSF----------- 376
EQHRQKHFEKRR PAANLIQ WR Y+ D ++ ATW + L +
Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATWKPHLKALHTCSPTKKEQGEAS 414
Query: 377 --------------------SSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQV 416
S ++ K+R+RM S + ++ S+Q A SPS++
Sbjct: 415 SSKFCSNKQKLFRMYTSRKQSQKLSFKERVRMASPRGQSIKSRQ--ASVGDRRSPSTDIT 472
Query: 417 GEATSPTKVQKSWSFNDRTRFRASLRL-----KPRTSAEDA-PSEEVAEEKSYQCELTVD 470
E SPTKVQKSWSFNDRTRFR SLRL KP A+ A +++V +EK QC+++V+
Sbjct: 473 AEG-SPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVE 531
Query: 471 DIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVD 530
D+ P +KTVIR+IRI+KF VAKRKFKETLRPYDVKDVIEQYSAGHLDML RIKSLQTRVD
Sbjct: 532 DLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVD 591
Query: 531 QIVGRG--PGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSR 588
QI+G+G D+K+RE K ++ E D++SM+GRVVKVEKQVQSIE KLD LL Y +
Sbjct: 592 QILGKGQITSDKKSRE---KITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQ 648
Query: 589 CLRSGTSA--SLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLS-ISRSVSTNM 640
LR G+++ +L + Q+P F+ + TSDY SPVD +D+S SAQ +SRS S N+
Sbjct: 649 VLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANI 703
>gi|26051260 potassium voltage-gated channel KQT-like protein 2
isoform c [Homo sapiens]
Length = 844
Score = 665 bits (1715), Expect = 0.0
Identities = 355/642 (55%), Positives = 444/642 (69%), Gaps = 59/642 (9%)
Query: 38 GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97
G +P+R +L P GA G+G + + YR+LQN++YNVLERPRGW
Sbjct: 44 GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91
Query: 98 AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157
AF+YH ++FLLVFSCLVLSV STI+E+++ + L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 92 AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151
Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217
CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211
Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277
DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK N F +YAD+LWWG
Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271
Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337
ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331
Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSIL------------------------ 373
RR PAA LIQ+AWR Y+T++SR L +TW YY+ +
Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPPLNQLELLRNLKSKS 391
Query: 374 -----------PSFSSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSP 422
PS S ++ +KDR+ S + K T+ SPS++Q E SP
Sbjct: 392 GLAFRKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKGKGSPQAQTVRRSPSADQSLE-DSP 449
Query: 423 TKVQKSWSFNDRTRFRASLRLK---PRTSAEDA--PSEEVAEEKSYQCELTVDDIMPAVK 477
+KV KSWSF DR+R R + R+K R ++E+A P E++ ++KS CE +D+ P +K
Sbjct: 450 SKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLK 509
Query: 478 TVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGP 537
IR++ +++FLV+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ+RVDQIVGRGP
Sbjct: 510 VSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGP 569
Query: 538 GDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSAS 597
+ KGP++AE+ ++ SMMGR+ KVEKQV S+E KLD L+ Y + R G +
Sbjct: 570 A--ITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPT 625
Query: 598 LGAVQVPLFDPDITSDYHSPVD-HEDISVSAQTLSISRSVST 638
+P+ YHSP D E + + I RS S+
Sbjct: 626 ETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSS 667
>gi|26051266 potassium voltage-gated channel KQT-like protein 2
isoform d [Homo sapiens]
Length = 841
Score = 662 bits (1709), Expect = 0.0
Identities = 353/638 (55%), Positives = 444/638 (69%), Gaps = 54/638 (8%)
Query: 38 GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97
G +P+R +L P GA G+G + + YR+LQN++YNVLERPRGW
Sbjct: 44 GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91
Query: 98 AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157
AF+YH ++FLLVFSCLVLSV STI+E+++ + L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 92 AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151
Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217
CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211
Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277
DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK N F +YAD+LWWG
Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271
Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337
ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331
Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDS--ILPSFSSRMGIKDRIRM------- 388
RR PAA LIQ+AWR Y+T++SR L +TW YY+ +P +SS+ R+
Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQL 391
Query: 389 ----------GSSQRRTGPSKQHLAP-------------PTMPTSPSSEQVGEATSPTKV 425
G + R+ P + +P T+ SPS++Q E SP+KV
Sbjct: 392 ELLRNLKSKSGLAFRKDPPPEPSPSPRGVAAKGKGSPQAQTVRRSPSADQSLE-DSPSKV 450
Query: 426 QKSWSFNDRTRFRASLRLKPRTSAEDA----PSEEVAEEKSYQCELTVDDIMPAVKTVIR 481
KSWSF DR+R R + R+K S +++ P E++ ++KS CE +D+ P +K IR
Sbjct: 451 PKSWSFGDRSRARQAFRIKGAASRQNSEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIR 510
Query: 482 SIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRK 541
++ +++FLV+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ+RVDQIVGRGP
Sbjct: 511 AVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPA--I 568
Query: 542 AREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAV 601
+ KGP++AE+ ++ SMMGR+ KVEKQV S+E KLD L+ Y + R G +
Sbjct: 569 TDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEA 626
Query: 602 QVPLFDPDITSDYHSPVD-HEDISVSAQTLSISRSVST 638
+P+ YHSP D E + + I RS S+
Sbjct: 627 YFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSS 664
>gi|26051262 potassium voltage-gated channel KQT-like protein 2
isoform b [Homo sapiens]
Length = 854
Score = 661 bits (1705), Expect = 0.0
Identities = 355/652 (54%), Positives = 444/652 (68%), Gaps = 69/652 (10%)
Query: 38 GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97
G +P+R +L P GA G+G + + YR+LQN++YNVLERPRGW
Sbjct: 44 GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91
Query: 98 AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157
AF+YH ++FLLVFSCLVLSV STI+E+++ + L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 92 AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151
Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217
CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211
Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277
DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK N F +YAD+LWWG
Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271
Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337
ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331
Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSIL------------------------ 373
RR PAA LIQ+AWR Y+T++SR L +TW YY+ +
Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQL 391
Query: 374 ---------------------PSFSSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPS 412
PS S ++ +KDR+ S + K T+ SPS
Sbjct: 392 ELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKGKGSPQAQTVRRSPS 450
Query: 413 SEQVGEATSPTKVQKSWSFNDRTRFRASLRLK---PRTSAEDA--PSEEVAEEKSYQCEL 467
++Q E SP+KV KSWSF DR+R R + R+K R ++E+A P E++ ++KS CE
Sbjct: 451 ADQSLE-DSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEF 509
Query: 468 TVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQT 527
+D+ P +K IR++ +++FLV+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ+
Sbjct: 510 VTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQS 569
Query: 528 RVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYS 587
RVDQIVGRGP + KGP++AE+ ++ SMMGR+ KVEKQV S+E KLD L+ Y
Sbjct: 570 RVDQIVGRGPA--ITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYM 627
Query: 588 RCLRSGTSASLGAVQVPLFDPDITSDYHSPVD-HEDISVSAQTLSISRSVST 638
+ R G + +P+ YHSP D E + + I RS S+
Sbjct: 628 Q--RMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSS 677
>gi|26051264 potassium voltage-gated channel KQT-like protein 2
isoform a [Homo sapiens]
Length = 872
Score = 648 bits (1672), Expect = 0.0
Identities = 356/668 (53%), Positives = 444/668 (66%), Gaps = 83/668 (12%)
Query: 38 GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97
G +P+R +L P GA G+G + + YR+LQN++YNVLERPRGW
Sbjct: 44 GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91
Query: 98 AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157
AF+YH ++FLLVFSCLVLSV STI+E+++ + L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 92 AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151
Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217
CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211
Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277
DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK N F +YAD+LWWG
Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271
Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337
ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331
Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDS--ILPSFSSRMGIKDRIRM-----GS 390
RR PAA LIQ+AWR Y+T++SR L +TW YY+ +P +SS+ R+
Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQL 391
Query: 391 SQRRTGPSKQHLA----PPTMPT------------------------------------- 409
R SK LA PP P+
Sbjct: 392 ELLRNLKSKSGLAFRKDPPPEPSPSKGSPCRGPLCGCCPGRSSQKVSLKDRVFSSPRGVA 451
Query: 410 -----SPSSEQVGEATS--------PTKVQKSWSFNDRTRFRASLRLK---PRTSAEDA- 452
SP ++ V + S P+KV KSWSF DR+R R + R+K R ++E+A
Sbjct: 452 AKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEAS 511
Query: 453 -PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQY 511
P E++ ++KS CE +D+ P +K IR++ +++FLV+KRKFKE+LRPYDV DVIEQY
Sbjct: 512 LPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQY 571
Query: 512 SAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQ 571
SAGHLDML RIKSLQ+RVDQIVGRGP + KGP++AE+ ++ SMMGR+ KVEKQ
Sbjct: 572 SAGHLDMLSRIKSLQSRVDQIVGRGPA--ITDKDRTKGPAEAELPEDPSMMGRLGKVEKQ 629
Query: 572 VQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVD-HEDISVSAQTL 630
V S+E KLD L+ Y + R G + +P+ YHSP D E + +
Sbjct: 630 VLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIV 687
Query: 631 SISRSVST 638
I RS S+
Sbjct: 688 KIVRSSSS 695
>gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo
sapiens]
Length = 872
Score = 571 bits (1471), Expect = e-163
Identities = 316/628 (50%), Positives = 413/628 (65%), Gaps = 73/628 (11%)
Query: 7 RRLGLGPPPGDAPRAELVALTAVQSEQG----EAGGGGSPRRLGLLGSPLPPGAPLPGPG 62
R++GL P GD + L AL A + G E GG +R G L PL P
Sbjct: 41 RKVGLAP--GDVEQVTL-ALGAGADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPV 97
Query: 63 SGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQ 122
+R++A +YRR+Q +Y+ LERPRGWA +YH +FL+V CL+L+VL+T +
Sbjct: 98 --------KRNNA---KYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFK 146
Query: 123 EHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVF 182
E++ ++ + LL+LE I +FG E+ +R+W+AGCCCRY+GW+GR +FARKP C++D V
Sbjct: 147 EYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVL 206
Query: 183 VASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAW 242
+ASV V+A G QGN+ ATS LRS+RFLQILRM+RMDRRGGTWKLLGS + AHSKELITAW
Sbjct: 207 IASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAW 265
Query: 243 YIGFLVLIFASFLVYLAEKDA----------NSDFSSYADSLWWGTITLTTIGYGDKTPH 292
YIGFL LI +SFLVYL EKD +F +YAD+LWWG ITL TIGYGDKTP
Sbjct: 266 YIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPK 325
Query: 293 TWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRL 352
TW GR++AA F+L+G+SFFALPAGILGSG ALKVQEQHRQKHFEKRR PAA LIQAAWR
Sbjct: 326 TWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRY 385
Query: 353 YSTDMSRAYLTATWYYYDSIL--PSF---------SSRMGIKDRIRMGSSQRRTGPSKQH 401
Y+T+ +R L ATW +Y+S++ P F S ++G+ DR+R+ S R +K
Sbjct: 386 YATNPNRIDLVATWRFYESVVSFPFFRKEQLEAASSQKLGLLDRVRL--SNPRGSNTKGK 443
Query: 402 LAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRT---SAEDA-PSEEV 457
L P + + + E SP+K K N++ RFR + R+K S+EDA + +
Sbjct: 444 LFTPL-----NVDAIEE--SPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPM 496
Query: 458 AEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLD 517
AE++ Y + ++D++P +K IR++RIL+F + K+KFKETLRPYDVKDVIEQYSAGHLD
Sbjct: 497 AEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLD 556
Query: 518 MLGRIKSLQTRVDQIVGRGPGDRKAREKGDKG-------------------PSDAEVVDE 558
ML RIK LQTR+D I GP +K KG PS +E+ D+
Sbjct: 557 MLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQ 616
Query: 559 ISMMGRVVKVEKQVQSIEHKLDLLLGFY 586
SMMG+ VKVE+QVQ + KLD L+ +
Sbjct: 617 -SMMGKFVKVERQVQDMGKKLDFLVDMH 643
>gi|236462242 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 5 [Homo sapiens]
Length = 822
Score = 510 bits (1314), Expect = e-144
Identities = 252/339 (74%), Positives = 281/339 (82%), Gaps = 24/339 (7%)
Query: 37 GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87
GGGG R R+ LLG PL S +S + +YRR+QN++
Sbjct: 70 GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115
Query: 88 YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147
YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+
Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175
Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207
I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R
Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235
Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267
FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F
Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295
Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327
S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ
Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355
Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATW 366
EQHRQKHFEKRR PAANLIQ WR Y+ D ++ ATW
Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATW 393
Score = 182 bits (461), Expect = 1e-45
Identities = 103/164 (62%), Positives = 126/164 (76%), Gaps = 8/164 (4%)
Query: 482 SIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGD 539
S RI+KF VAKRKFKETLRPYDVKDVIEQYSAGHLDML RIKSLQTRVDQI+G+G D
Sbjct: 414 SSRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSD 473
Query: 540 RKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--S 597
+K+RE K ++ E D++SM+GRVVKVEKQVQSIE KLD LL Y + LR G+++ +
Sbjct: 474 KKSRE---KITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALA 530
Query: 598 LGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLS-ISRSVSTNM 640
L + Q+P F+ + TSDY SPVD +D+S SAQ +SRS S N+
Sbjct: 531 LASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANI 574
>gi|26051268 potassium voltage-gated channel KQT-like protein 2
isoform e [Homo sapiens]
Length = 393
Score = 482 bits (1240), Expect = e-136
Identities = 231/333 (69%), Positives = 273/333 (81%), Gaps = 12/333 (3%)
Query: 38 GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97
G +P+R +L P GA G+G + + YR+LQN++YNVLERPRGW
Sbjct: 44 GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91
Query: 98 AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157
AF+YH ++FLLVFSCLVLSV STI+E+++ + L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 92 AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151
Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217
CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211
Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277
DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK N F +YAD+LWWG
Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271
Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337
ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331
Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYD 370
RR PAA LIQ+AWR Y+T++SR L +TW YY+
Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYE 364
>gi|32479527 potassium voltage-gated channel, KQT-like subfamily,
member 1 isoform 1 [Homo sapiens]
Length = 676
Score = 413 bits (1062), Expect = e-115
Identities = 259/640 (40%), Positives = 360/640 (56%), Gaps = 93/640 (14%)
Query: 2 AEAPPR----RLGLGPPPG----DAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLP 53
A +PPR R G G PG A A+ + +E G AGG L +P+
Sbjct: 4 ASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGA--------LYAPIA 55
Query: 54 PGAPLPGPGSGSGSACGQ----------------RSSAAHKRY-----RRLQNWVYNVLE 92
PGAP P P + + R S R +Q VYN LE
Sbjct: 56 PGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLE 115
Query: 93 RPRGW-AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRV 151
RP GW FVYH +FL+V CL+ SVLSTI+++ LA L +E V++V FG EY+VR+
Sbjct: 116 RPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRL 175
Query: 152 WSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQI 211
WSAGC +Y G GR RFARKP +ID IV VAS+ V+ G++G +FATSA+R +RFLQI
Sbjct: 176 WSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQI 235
Query: 212 LRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDA-----NSD 266
LRM+ +DR+GGTW+LLGSVV+ H +ELIT YIGFL LIF+S+ VYLAEKDA +
Sbjct: 236 LRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVE 295
Query: 267 FSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKV 326
F SYAD+LWWG +T+TTIGYGDK P TW+G+ +A+ F++ ISFFALPAGILGSGFALKV
Sbjct: 296 FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKV 355
Query: 327 QEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYY--------DSILPSFSS 378
Q++ RQKHF ++ AA+LIQ AWR Y+ + ++TW Y + PS
Sbjct: 356 QQKQRQKHFNRQIPAAASLIQTAWRCYAAENPD---SSTWKIYIRKAPRSHTLLSPSPKP 412
Query: 379 RMGI---KDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQ-----------VGEATSPTK 424
+ + K + ++ T P ++ L P + P E+ SPT
Sbjct: 413 KKSVVVKKKKFKLDKDNGVT-PGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTL 471
Query: 425 VQKSWSFNDRTR-FRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSI 483
++ S RT F L L+ T P +++ + + + I+ I
Sbjct: 472 LEVSMPHFMRTNSFAEDLDLEGETLL--TPITHISQLREHH------------RATIKVI 517
Query: 484 RILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAR 543
R +++ VAK+KF++ +PYDV+DVIEQYS GHL+++ RIK LQ R+DQ +G+
Sbjct: 518 RRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVS 577
Query: 544 EKG-DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLL 582
EK D+G + ++ R+ +VE +V ++ +L L+
Sbjct: 578 EKSKDRGSN--------TIGARLNRVEDKVTQLDQRLALI 609
>gi|32479525 potassium voltage-gated channel, KQT-like subfamily,
member 1 isoform 2 [Homo sapiens]
Length = 549
Score = 379 bits (973), Expect = e-105
Identities = 218/506 (43%), Positives = 309/506 (61%), Gaps = 55/506 (10%)
Query: 106 FLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQG 165
FL+V CL+ SVLSTI+++ LA L +E V++V FG EY+VR+WSAGC +Y G G
Sbjct: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
Query: 166 RFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWK 225
R RFARKP +ID IV VAS+ V+ G++G +FATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
Query: 226 LLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDA-----NSDFSSYADSLWWGTIT 280
LLGSVV+ H +ELIT YIGFL LIF+S+ VYLAEKDA +F SYAD+LWWG +T
Sbjct: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182
Query: 281 LTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRM 340
+TTIGYGDK P TW+G+ +A+ F++ ISFFALPAGILGSGFALKVQ++ RQKHF ++
Sbjct: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242
Query: 341 PAANLIQAAWRLYSTDMSRAYLTATWYYY--------DSILPSFSSRMGI---KDRIRMG 389
AA+LIQ AWR Y+ + ++TW Y + PS + + K + ++
Sbjct: 243 AAASLIQTAWRCYAAENPD---SSTWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLD 299
Query: 390 SSQRRTGPSKQHLAPPTMPTSPSSEQ-----------VGEATSPTKVQKSWSFNDRTR-F 437
T P ++ L P + P E+ SPT ++ S RT F
Sbjct: 300 KDNGVT-PGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSF 358
Query: 438 RASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKE 497
L L+ T P +++ + + + I+ IR +++ VAK+KF++
Sbjct: 359 AEDLDLEGETLL--TPITHISQLREHH------------RATIKVIRRMQYFVAKKKFQQ 404
Query: 498 TLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG-DKGPSDAEVV 556
+PYDV+DVIEQYS GHL+++ RIK LQ R+DQ +G+ EK D+G +
Sbjct: 405 ARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSN----- 459
Query: 557 DEISMMGRVVKVEKQVQSIEHKLDLL 582
++ R+ +VE +V ++ +L L+
Sbjct: 460 ---TIGARLNRVEDKVTQLDQRLALI 482
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 104 bits (259), Expect = 3e-22
Identities = 106/406 (26%), Positives = 185/406 (45%), Gaps = 49/406 (12%)
Query: 87 VYNVLERPRGWA---FVYHVFIFLLVFSCLVLSVLSTIQEHQELA-------NECLLILE 136
++++LE+P + + I +V S + LS L+T+ E Q L N L +E
Sbjct: 175 LWDLLEKPNSSVAAKILAIISIMFIVLSTIALS-LNTLPELQSLDEFGQSTDNPQLAHVE 233
Query: 137 FVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVAS-VAVIAAGTQG 195
V I F +EY++R S+ +++F + P ID + + V + +
Sbjct: 234 AVCIAWFTMEYLLRFLSS---------PKKWKFFKGPLNAIDLLAILPYYVTIFLTESNK 284
Query: 196 NIFATSALRSM----RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLI 250
++ +R + R ++ILR++++ R + LG + EL + ++ ++I
Sbjct: 285 SVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMI 344
Query: 251 FASFLVYLAEKDAN-SDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGIS 309
F+S LV+ AEKD + + F S S WW TIT+TT+GYGD P T LG+++ + G+
Sbjct: 345 FSS-LVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVL 403
Query: 310 FFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYY 369
ALP I+ + F+ +EQ RQ+ KRR A + + S +M A+ +
Sbjct: 404 VIALPIPIIVNNFSEFYKEQKRQEKAIKRR-EALERAKRNGSIVSMNMKDAFARSI-EMM 461
Query: 370 DSILPSFSSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSE--QVGEATSPTKVQK 427
D ++ MG KD+++ P+K T+ + SS+ + E SP K +
Sbjct: 462 DIVVEKNGENMGKKDKVQ----DNHLSPNKWKWTKRTLSETSSSKSFETKEQGSPEKARS 517
Query: 428 SWS--------FNDRTRFRASLRLKP-----RTSAEDAPSEEVAEE 460
S S D A + +P ++A+ P EE+ E
Sbjct: 518 SSSPQHLNVQQLEDMYNKMAKTQSQPILNTKESAAQSKPKEELEME 563
>gi|27436974 potassium voltage-gated channel, Shab-related
subfamily, member 2 [Homo sapiens]
Length = 911
Score = 99.4 bits (246), Expect = 9e-21
Identities = 79/269 (29%), Positives = 136/269 (50%), Gaps = 26/269 (9%)
Query: 87 VYNVLERPRGWA---FVYHVFIFLLVFSCLVLSV--LSTIQEHQELA----NECLLILEF 137
++++LE+P + V I +V S + LS+ L +QE E N L +E
Sbjct: 179 LWDLLEKPNSSVAAKILAIVSILFIVLSTIALSLNTLPELQETDEFGQLNDNRQLAHVEA 238
Query: 138 VMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVAS-VAVIAAGTQGN 196
V I F +EY++R S+ +++F + P VID + + V + + +
Sbjct: 239 VCIAWFTMEYLLRFLSS---------PNKWKFFKGPLNVIDLLAILPYYVTIFLTESNKS 289
Query: 197 IFATSALRSM----RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLIF 251
+ +R + R ++ILR++++ R + LG + EL + ++ ++IF
Sbjct: 290 VLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIF 349
Query: 252 ASFLVYLAEKDANSD-FSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISF 310
+S LV+ AEKD ++ F+S S WW TIT+TT+GYGD P T LG+++ + G+
Sbjct: 350 SS-LVFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLV 408
Query: 311 FALPAGILGSGFALKVQEQHRQKHFEKRR 339
ALP I+ + F+ +EQ RQ+ KRR
Sbjct: 409 IALPIPIIVNNFSEFYKEQKRQEKAIKRR 437
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 90.9 bits (224), Expect = 3e-18
Identities = 80/318 (25%), Positives = 141/318 (44%), Gaps = 63/318 (19%)
Query: 43 RRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERP---RGWAF 99
+RLG+ A L GP SG R+RRLQ ++ + E P R F
Sbjct: 188 KRLGI-----EDAAGLGGPDGKSG------------RWRRLQPRMWALFEDPYSSRAARF 230
Query: 100 VYHVFIFLLVFS----CL---------------VLSVLSTIQEHQELANECLLILEFVMI 140
+ +F ++ S CL V++ S + +++ + L +E V +
Sbjct: 231 IAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCV 290
Query: 141 VVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV---FVASVAVIAAGTQGNI 197
V F E++VR+ + + F + +IDF+ F V + ++
Sbjct: 291 VWFTFEFLVRIVFS---------PNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAK 341
Query: 198 FATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIGFLVLIFASFLV 256
LR +RF++ILR+ ++ R ++LG + A + E L+ ++ VLIFA+ ++
Sbjct: 342 DVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFAT-MI 400
Query: 257 YLAEK----------DANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALL 306
Y AE+ ++ F + WW +T+TT+GYGD P TW G ++ A AL
Sbjct: 401 YYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALA 460
Query: 307 GISFFALPAGILGSGFAL 324
G+ A+P ++ + F +
Sbjct: 461 GVLTIAMPVPVIVNNFGM 478
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 90.9 bits (224), Expect = 3e-18
Identities = 80/318 (25%), Positives = 141/318 (44%), Gaps = 63/318 (19%)
Query: 43 RRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERP---RGWAF 99
+RLG+ A L GP SG R+RRLQ ++ + E P R F
Sbjct: 188 KRLGI-----EDAAGLGGPDGKSG------------RWRRLQPRMWALFEDPYSSRAARF 230
Query: 100 VYHVFIFLLVFS----CL---------------VLSVLSTIQEHQELANECLLILEFVMI 140
+ +F ++ S CL V++ S + +++ + L +E V +
Sbjct: 231 IAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCV 290
Query: 141 VVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV---FVASVAVIAAGTQGNI 197
V F E++VR+ + + F + +IDF+ F V + ++
Sbjct: 291 VWFTFEFLVRIVFS---------PNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAK 341
Query: 198 FATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIGFLVLIFASFLV 256
LR +RF++ILR+ ++ R ++LG + A + E L+ ++ VLIFA+ ++
Sbjct: 342 DVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFAT-MI 400
Query: 257 YLAEK----------DANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALL 306
Y AE+ ++ F + WW +T+TT+GYGD P TW G ++ A AL
Sbjct: 401 YYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALA 460
Query: 307 GISFFALPAGILGSGFAL 324
G+ A+P ++ + F +
Sbjct: 461 GVLTIAMPVPVIVNNFGM 478
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 90.9 bits (224), Expect = 3e-18
Identities = 80/318 (25%), Positives = 141/318 (44%), Gaps = 63/318 (19%)
Query: 43 RRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERP---RGWAF 99
+RLG+ A L GP SG R+RRLQ ++ + E P R F
Sbjct: 188 KRLGI-----EDAAGLGGPDGKSG------------RWRRLQPRMWALFEDPYSSRAARF 230
Query: 100 VYHVFIFLLVFS----CL---------------VLSVLSTIQEHQELANECLLILEFVMI 140
+ +F ++ S CL V++ S + +++ + L +E V +
Sbjct: 231 IAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCV 290
Query: 141 VVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV---FVASVAVIAAGTQGNI 197
V F E++VR+ + + F + +IDF+ F V + ++
Sbjct: 291 VWFTFEFLVRIVFS---------PNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAK 341
Query: 198 FATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIGFLVLIFASFLV 256
LR +RF++ILR+ ++ R ++LG + A + E L+ ++ VLIFA+ ++
Sbjct: 342 DVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFAT-MI 400
Query: 257 YLAEK----------DANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALL 306
Y AE+ ++ F + WW +T+TT+GYGD P TW G ++ A AL
Sbjct: 401 YYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALA 460
Query: 307 GISFFALPAGILGSGFAL 324
G+ A+P ++ + F +
Sbjct: 461 GVLTIAMPVPVIVNNFGM 478
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 90.5 bits (223), Expect = 4e-18
Identities = 86/351 (24%), Positives = 155/351 (44%), Gaps = 51/351 (14%)
Query: 25 ALTAVQSEQGEAGGGGSPRRLG-----LLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKR 79
AL +S G G G G L L P G G+GSG G + +
Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQP----RM 212
Query: 80 YRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCL--------------VLSV--LSTIQE 123
+ ++ + R +A ++ + + + F CL +L V ++++
Sbjct: 213 WALFEDPYSSRAARVVAFASLFFILVSITTF-CLETHEAFNIDRNVTEILRVGNITSVHF 271
Query: 124 HQELANECLLI-LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV- 181
+E+ E +L +E V ++ F LE++VR+ CC F + +IDF+
Sbjct: 272 RREVETEPILTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAI 322
Query: 182 --FVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-L 238
F V + ++ LR +RF++ILR+ ++ R ++LG + A + E L
Sbjct: 323 LPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFL 382
Query: 239 ITAWYIGFLVLIFASFLVYLAEK----------DANSDFSSYADSLWWGTITLTTIGYGD 288
+ ++ VLIFA+ ++Y AE+ + ++DF + WW +T+TT+GYGD
Sbjct: 383 LLIIFLALGVLIFAT-MIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGD 441
Query: 289 KTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRR 339
P TW G ++ A AL G+ A+P ++ + F + ++ K+R
Sbjct: 442 MYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 90.5 bits (223), Expect = 4e-18
Identities = 86/351 (24%), Positives = 155/351 (44%), Gaps = 51/351 (14%)
Query: 25 ALTAVQSEQGEAGGGGSPRRLG-----LLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKR 79
AL +S G G G G L L P G G+GSG G + +
Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQP----RM 212
Query: 80 YRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCL--------------VLSV--LSTIQE 123
+ ++ + R +A ++ + + + F CL +L V ++++
Sbjct: 213 WALFEDPYSSRAARVVAFASLFFILVSITTF-CLETHEAFNIDRNVTEILRVGNITSVHF 271
Query: 124 HQELANECLLI-LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV- 181
+E+ E +L +E V ++ F LE++VR+ CC F + +IDF+
Sbjct: 272 RREVETEPILTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAI 322
Query: 182 --FVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-L 238
F V + ++ LR +RF++ILR+ ++ R ++LG + A + E L
Sbjct: 323 LPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFL 382
Query: 239 ITAWYIGFLVLIFASFLVYLAEK----------DANSDFSSYADSLWWGTITLTTIGYGD 288
+ ++ VLIFA+ ++Y AE+ + ++DF + WW +T+TT+GYGD
Sbjct: 383 LLIIFLALGVLIFAT-MIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGD 441
Query: 289 KTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRR 339
P TW G ++ A AL G+ A+P ++ + F + ++ K+R
Sbjct: 442 MYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 90.5 bits (223), Expect = 4e-18
Identities = 86/351 (24%), Positives = 155/351 (44%), Gaps = 51/351 (14%)
Query: 25 ALTAVQSEQGEAGGGGSPRRLG-----LLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKR 79
AL +S G G G G L L P G G+GSG G + +
Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQP----RM 212
Query: 80 YRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCL--------------VLSV--LSTIQE 123
+ ++ + R +A ++ + + + F CL +L V ++++
Sbjct: 213 WALFEDPYSSRAARVVAFASLFFILVSITTF-CLETHEAFNIDRNVTEILRVGNITSVHF 271
Query: 124 HQELANECLLI-LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV- 181
+E+ E +L +E V ++ F LE++VR+ CC F + +IDF+
Sbjct: 272 RREVETEPILTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAI 322
Query: 182 --FVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-L 238
F V + ++ LR +RF++ILR+ ++ R ++LG + A + E L
Sbjct: 323 LPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFL 382
Query: 239 ITAWYIGFLVLIFASFLVYLAEK----------DANSDFSSYADSLWWGTITLTTIGYGD 288
+ ++ VLIFA+ ++Y AE+ + ++DF + WW +T+TT+GYGD
Sbjct: 383 LLIIFLALGVLIFAT-MIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGD 441
Query: 289 KTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRR 339
P TW G ++ A AL G+ A+P ++ + F + ++ K+R
Sbjct: 442 MYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492
>gi|6912444 potassium voltage-gated channel, subfamily G, member 2
[Homo sapiens]
Length = 466
Score = 90.1 bits (222), Expect = 6e-18
Identities = 99/345 (28%), Positives = 144/345 (41%), Gaps = 46/345 (13%)
Query: 17 DAPRAELVALTAVQSEQGEAGGG-GSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSA 75
D R E L ++ + EA P G GSP A G R
Sbjct: 111 DEARLERCCLRRLRRREEEAAEARAGPTERGAQGSP--------------ARALGPRGRL 156
Query: 76 AHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSC-LVLSVLSTIQEHQELANEC--- 131
R RRL++ V N G F F+ V + L LS + I+ +E EC
Sbjct: 157 QRGR-RRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEE-RGECSPK 214
Query: 132 ---LLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV----FVA 184
L +LE V + F E+++R A C F R P +ID + +V+
Sbjct: 215 CRSLFVLETVCVAWFSFEFLLRSLQAESKCA---------FLRAPLNIIDILALLPFYVS 265
Query: 185 SVAVIAAGTQGNIFATSA---LRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITA 241
+ +AAG G A LR +R L++L ++R+ R + LG + ++E
Sbjct: 266 LLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREF--G 323
Query: 242 WYIGFLVLIFASF--LVYLAEKD--ANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGR 297
+ FL + A F LV+LAE++ A DFSS S WW I++TT+GYGD P + G+
Sbjct: 324 LLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQ 383
Query: 298 VLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPA 342
V+A L GI A P + F+ E Q+ PA
Sbjct: 384 VVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPA 428
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 88.2 bits (217), Expect = 2e-17
Identities = 59/229 (25%), Positives = 112/229 (48%), Gaps = 16/229 (6%)
Query: 135 LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQ 194
L+ +++F +EY++R+++A R+RF R +ID + + I
Sbjct: 229 LDTACVMIFTVEYLLRLFAA---------PSRYRFIRSVMSIIDVVAIMPYY--IGLVMT 277
Query: 195 GNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLIFAS 253
N + A ++R ++ R+ + R ++LG + + + EL + + ++IFA+
Sbjct: 278 NNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFAT 337
Query: 254 FLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFAL 313
+ Y + + S F+S S W+ +T+TT+GYGD P T G++ + +L G+ AL
Sbjct: 338 VMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIAL 397
Query: 314 PAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYL 362
P ++ S F+ + H+ + +KRR + A R+ T S AYL
Sbjct: 398 PVPVIVSNFS---RIYHQNQRADKRRAQKKARL-ARIRVAKTGSSNAYL 442
>gi|27436986 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 2 [Homo sapiens]
Length = 636
Score = 88.2 bits (217), Expect = 2e-17
Identities = 59/229 (25%), Positives = 112/229 (48%), Gaps = 16/229 (6%)
Query: 135 LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQ 194
L+ +++F +EY++R+++A R+RF R +ID + + I
Sbjct: 229 LDTACVMIFTVEYLLRLFAA---------PSRYRFIRSVMSIIDVVAIMPYY--IGLVMT 277
Query: 195 GNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLIFAS 253
N + A ++R ++ R+ + R ++LG + + + EL + + ++IFA+
Sbjct: 278 NNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFAT 337
Query: 254 FLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFAL 313
+ Y + + S F+S S W+ +T+TT+GYGD P T G++ + +L G+ AL
Sbjct: 338 VMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIAL 397
Query: 314 PAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYL 362
P ++ S F+ + H+ + +KRR + A R+ T S AYL
Sbjct: 398 PVPVIVSNFS---RIYHQNQRADKRRAQKKARL-ARIRVAKTGSSNAYL 442
>gi|88758565 potassium voltage-gated channel, shaker-related
subfamily, member 3 [Homo sapiens]
Length = 575
Score = 87.4 bits (215), Expect = 4e-17
Identities = 56/196 (28%), Positives = 97/196 (49%), Gaps = 16/196 (8%)
Query: 134 ILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIA--- 190
++E + I+ F E +VR ++ + F+R +ID + + +
Sbjct: 297 VVETLCIIWFSFELLVRFFAC---------PSKATFSRNIMNLIDIVAIIPYFITLGTEL 347
Query: 191 AGTQGN---IFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFL 247
A QGN + + LR +R +++ R+ ++ R ++LG + A +EL + F+
Sbjct: 348 AERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFI 407
Query: 248 VLIFASFLVYLAEKD-ANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALL 306
+I S VY AE D S FSS D+ WW +T+TT+GYGD P T G+++ + A+
Sbjct: 408 GVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIA 467
Query: 307 GISFFALPAGILGSGF 322
G+ ALP ++ S F
Sbjct: 468 GVLTIALPVPVIVSNF 483
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 86.7 bits (213), Expect = 6e-17
Identities = 57/207 (27%), Positives = 105/207 (50%), Gaps = 6/207 (2%)
Query: 119 STIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVID 178
+T+ + + + I+E + I+ F E +VR ++ C + ++ F +I
Sbjct: 208 TTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFA--CPSKTDFFKNIMNFI-DIVAIIP 264
Query: 179 FIVFVASVAVIAAGTQGNIFATSA--LRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSK 236
+ + + + G Q ATS LR +R +++ R+ ++ R ++LG + A +
Sbjct: 265 YFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMR 324
Query: 237 ELITAWYIGFLVLIFASFLVYLAE-KDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWL 295
EL + F+ +I S VY AE ++A S FSS D+ WW +++TT+GYGD P T
Sbjct: 325 ELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIG 384
Query: 296 GRVLAAGFALLGISFFALPAGILGSGF 322
G+++ + A+ G+ ALP ++ S F
Sbjct: 385 GKIVGSLCAIAGVLTIALPVPVIVSNF 411
>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
[Homo sapiens]
Length = 494
Score = 86.3 bits (212), Expect = 8e-17
Identities = 73/255 (28%), Positives = 117/255 (45%), Gaps = 24/255 (9%)
Query: 75 AAHKRYRRLQNWVYNVLERPRGW--AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANE-- 130
AA R+RR Q V+ LE+P A V V FLL+ V+ + TI E Q L E
Sbjct: 156 AAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQVLDAEGN 215
Query: 131 -----CLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV---F 182
L +E I F LEY++R++S+ + FA ++D + F
Sbjct: 216 RVEHPTLENVETACIGWFTLEYLLRLFSS---------PNKLHFALSFMNIVDVLAILPF 266
Query: 183 VASVAVIAAGTQGNIFAT--SALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-I 239
S+ + G + A++++R ++I R+ ++ R + L + KEL +
Sbjct: 267 YVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGL 326
Query: 240 TAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVL 299
Y+ + +F++ + + + F S S WW IT+TT+GYGD P T LG++
Sbjct: 327 LLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLN 386
Query: 300 AAGFALLGISFFALP 314
AA L G+ ALP
Sbjct: 387 AAISFLCGVIAIALP 401
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 85.5 bits (210), Expect = 1e-16
Identities = 59/233 (25%), Positives = 105/233 (45%), Gaps = 23/233 (9%)
Query: 129 NECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAV 188
N+ I+E V IV F E++VR ++ + F + +ID + +
Sbjct: 368 NDPFFIVETVCIVWFSFEFVVRCFAC---------PSQALFFKNIMNIIDIVSILPYFIT 418
Query: 189 IAA----------GTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL 238
+ G Q + + LR +R +++ R+ ++ R ++LG + A +EL
Sbjct: 419 LGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMREL 478
Query: 239 ITAWYIGFLVLIFASFLVYLAEKDA-NSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGR 297
+ F+ +I S VY AE D + F S D+ WW +T+TT+GYGD P T G+
Sbjct: 479 GLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGK 538
Query: 298 VLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAW 350
++ + A+ G+ ALP ++ S F HR+ E++ N + +
Sbjct: 539 IVGSLCAIAGVLTIALPVPVIVSNFN---YFYHRETENEEQTQLTQNAVSCPY 588
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,473,197
Number of Sequences: 37866
Number of extensions: 1266037
Number of successful extensions: 11043
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 189
Number of HSP's that attempted gapping in prelim test: 7271
Number of HSP's gapped (non-prelim): 3599
length of query: 641
length of database: 18,247,518
effective HSP length: 109
effective length of query: 532
effective length of database: 14,120,124
effective search space: 7511905968
effective search space used: 7511905968
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.