BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|26638653 potassium voltage-gated channel KQT-like protein 4 isoform a [Homo sapiens] (695 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|26638653 potassium voltage-gated channel KQT-like protein 4 i... 1395 0.0 gi|26638655 potassium voltage-gated channel KQT-like protein 4 i... 1233 0.0 gi|28373065 potassium voltage-gated channel, KQT-like subfamily,... 748 0.0 gi|236461942 potassium voltage-gated channel, KQT-like subfamily... 748 0.0 gi|236462079 potassium voltage-gated channel, KQT-like subfamily... 747 0.0 gi|236461719 potassium voltage-gated channel, KQT-like subfamily... 746 0.0 gi|26051264 potassium voltage-gated channel KQT-like protein 2 i... 682 0.0 gi|26051260 potassium voltage-gated channel KQT-like protein 2 i... 672 0.0 gi|26051262 potassium voltage-gated channel KQT-like protein 2 i... 668 0.0 gi|26051266 potassium voltage-gated channel KQT-like protein 2 i... 659 0.0 gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H... 559 e-159 gi|236462242 potassium voltage-gated channel, KQT-like subfamily... 510 e-144 gi|26051268 potassium voltage-gated channel KQT-like protein 2 i... 482 e-136 gi|32479527 potassium voltage-gated channel, KQT-like subfamily,... 397 e-110 gi|32479525 potassium voltage-gated channel, KQT-like subfamily,... 363 e-100 gi|27436974 potassium voltage-gated channel, Shab-related subfam... 99 1e-20 gi|4826784 potassium voltage-gated channel, Shab-related subfami... 96 1e-19 gi|21217561 Shaw-related voltage-gated potassium channel protein... 91 4e-18 gi|21217563 Shaw-related voltage-gated potassium channel protein... 91 4e-18 gi|24497458 Shaw-related voltage-gated potassium channel protein... 91 4e-18 gi|88758576 Shaw-related voltage-gated potassium channel protein... 91 5e-18 gi|24497462 Shaw-related voltage-gated potassium channel protein... 91 5e-18 gi|24497464 Shaw-related voltage-gated potassium channel protein... 91 5e-18 gi|6912444 potassium voltage-gated channel, subfamily G, member ... 90 6e-18 gi|27436984 potassium voltage-gated channel, Shal-related subfam... 88 2e-17 gi|27436986 potassium voltage-gated channel, Shal-related subfam... 88 2e-17 gi|88758565 potassium voltage-gated channel, shaker-related subf... 87 4e-17 gi|119395748 potassium voltage-gated channel subfamily A member ... 87 7e-17 gi|20070166 potassium voltage-gated channel, subfamily F, member... 86 9e-17 gi|4504817 potassium voltage-gated channel, shaker-related subfa... 86 2e-16 >gi|26638653 potassium voltage-gated channel KQT-like protein 4 isoform a [Homo sapiens] Length = 695 Score = 1395 bits (3611), Expect = 0.0 Identities = 695/695 (100%), Positives = 695/695 (100%) Query: 1 MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG 60 MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG Sbjct: 1 MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG 60 Query: 61 PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST 120 PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST Sbjct: 61 PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST 120 Query: 121 IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI 180 IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI Sbjct: 121 IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI 180 Query: 181 VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT 240 VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT Sbjct: 181 VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT 240 Query: 241 AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA 300 AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA Sbjct: 241 AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA 300 Query: 301 AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA 360 AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA Sbjct: 301 AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA 360 Query: 361 YLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHR 420 YLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHR Sbjct: 361 YLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHR 420 Query: 421 PGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ 480 PGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ Sbjct: 421 PGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ 480 Query: 481 KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL 540 KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL Sbjct: 481 KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL 540 Query: 541 KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG 600 KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG Sbjct: 541 KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG 600 Query: 601 DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF 660 DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF Sbjct: 601 DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF 660 Query: 661 DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD 695 DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD Sbjct: 661 DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD 695 >gi|26638655 potassium voltage-gated channel KQT-like protein 4 isoform b [Homo sapiens] Length = 641 Score = 1233 bits (3189), Expect = 0.0 Identities = 631/695 (90%), Positives = 634/695 (91%), Gaps = 54/695 (7%) Query: 1 MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG 60 MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG Sbjct: 1 MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG 60 Query: 61 PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST 120 PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST Sbjct: 61 PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST 120 Query: 121 IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI 180 IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI Sbjct: 121 IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI 180 Query: 181 VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT 240 VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT Sbjct: 181 VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT 240 Query: 241 AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA 300 AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA Sbjct: 241 AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA 300 Query: 301 AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA 360 AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA Sbjct: 301 AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA 360 Query: 361 YLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHR 420 YLTATWYYYDSILPSF + + + Sbjct: 361 YLTATWYYYDSILPSFSSRMGIKDRI---------------------------------- 386 Query: 421 PGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ 480 RMG SSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ Sbjct: 387 ------------RMG--------SSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ 426 Query: 481 KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL 540 KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL Sbjct: 427 KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL 486 Query: 541 KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG 600 KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG Sbjct: 487 KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG 546 Query: 601 DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF 660 DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF Sbjct: 547 DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF 606 Query: 661 DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD 695 DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD Sbjct: 607 DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD 641 >gi|28373065 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 1 [Homo sapiens] Length = 932 Score = 748 bits (1932), Expect = 0.0 Identities = 412/681 (60%), Positives = 488/681 (71%), Gaps = 89/681 (13%) Query: 37 GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87 GGGG R R+ LLG PL S +S + +YRR+QN++ Sbjct: 70 GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115 Query: 88 YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147 YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+ Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175 Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207 I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235 Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295 Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327 S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355 Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQ 387 EQHRQKHFEKRR PAANLIQ WR Y+ D ++ ATW Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATW--------------------- 393 Query: 388 RARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESS---RMGIKDRIRMGS 444 P + H T GE+S ++ K+R+RM S Sbjct: 394 ------------------------KPHLKALHTCSPTKKEQGEASSSQKLSFKERVRMAS 429 Query: 445 SQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRL-----KP 499 + ++ S+Q A SPS++ E SPTKVQKSWSFNDRTRFR SLRL KP Sbjct: 430 PRGQSIKSRQ--ASVGDRRSPSTDITAEG-SPTKVQKSWSFNDRTRFRPSLRLKSSQPKP 486 Query: 500 RTSAEDA-PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDV 558 A+ A +++V +EK QC+++V+D+ P +KTVIR+IRI+KF VAKRKFKETLRPYDV Sbjct: 487 VIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDV 546 Query: 559 KDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGDRKAREKGDKGPSDAEVVDEISMM 616 KDVIEQYSAGHLDML RIKSLQTRVDQI+G+G D+K+RE K ++ E D++SM+ Sbjct: 547 KDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSRE---KITAEHETTDDLSML 603 Query: 617 GRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--SLGAVQVPLFDPDITSDYHSPVDH 674 GRVVKVEKQVQSIE KLD LL Y + LR G+++ +L + Q+P F+ + TSDY SPVD Sbjct: 604 GRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDS 663 Query: 675 EDISVSAQTLS-ISRSVSTNM 694 +D+S SAQ +SRS S N+ Sbjct: 664 KDLSGSAQNSGCLSRSTSANI 684 >gi|236461942 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 3 [Homo sapiens] Length = 942 Score = 748 bits (1931), Expect = 0.0 Identities = 411/678 (60%), Positives = 491/678 (72%), Gaps = 73/678 (10%) Query: 37 GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87 GGGG R R+ LLG PL S +S + +YRR+QN++ Sbjct: 70 GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115 Query: 88 YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147 YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+ Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175 Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207 I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235 Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295 Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327 S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355 Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQ 387 EQHRQKHFEKRR PAANLIQ WR Y+ D ++ ATW + L + + Q Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATWKPHLKALHTCSPTNKFCSNKQ 414 Query: 388 RARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQR 447 + R R+ +S ++ K+R+RM S + Sbjct: 415 KL----FRMYTSRK----------------------------QSQKLSFKERVRMASPRG 442 Query: 448 RTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRL-----KPRTS 502 ++ S+Q A SPS++ E SPTKVQKSWSFNDRTRFR SLRL KP Sbjct: 443 QSIKSRQ--ASVGDRRSPSTDITAEG-SPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVID 499 Query: 503 AEDA-PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDV 561 A+ A +++V +EK QC+++V+D+ P +KTVIR+IRI+KF VAKRKFKETLRPYDVKDV Sbjct: 500 ADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDV 559 Query: 562 IEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGDRKAREKGDKGPSDAEVVDEISMMGRV 619 IEQYSAGHLDML RIKSLQTRVDQI+G+G D+K+RE K ++ E D++SM+GRV Sbjct: 560 IEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSRE---KITAEHETTDDLSMLGRV 616 Query: 620 VKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--SLGAVQVPLFDPDITSDYHSPVDHEDI 677 VKVEKQVQSIE KLD LL Y + LR G+++ +L + Q+P F+ + TSDY SPVD +D+ Sbjct: 617 VKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDL 676 Query: 678 SVSAQTLS-ISRSVSTNM 694 S SAQ +SRS S N+ Sbjct: 677 SGSAQNSGCLSRSTSANI 694 >gi|236462079 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 4 [Homo sapiens] Length = 951 Score = 747 bits (1929), Expect = 0.0 Identities = 409/678 (60%), Positives = 492/678 (72%), Gaps = 64/678 (9%) Query: 37 GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87 GGGG R R+ LLG PL S +S + +YRR+QN++ Sbjct: 70 GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115 Query: 88 YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147 YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+ Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175 Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207 I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235 Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295 Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327 S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355 Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQ 387 EQHRQKHFEKRR PAANLIQ WR Y+ D ++ ATW Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATW--------------------- 393 Query: 388 RARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQR 447 + L + + + S++ + + +S ++ K+R+RM S + Sbjct: 394 KPHLKALHTCSPTKKEQGEASSSKF--CSNKQKLFRMYTSRKQSQKLSFKERVRMASPRG 451 Query: 448 RTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRL-----KPRTS 502 ++ S+Q A SPS++ E SPTKVQKSWSFNDRTRFR SLRL KP Sbjct: 452 QSIKSRQ--ASVGDRRSPSTDITAEG-SPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVID 508 Query: 503 AEDA-PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDV 561 A+ A +++V +EK QC+++V+D+ P +KTVIR+IRI+KF VAKRKFKETLRPYDVKDV Sbjct: 509 ADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDV 568 Query: 562 IEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGDRKAREKGDKGPSDAEVVDEISMMGRV 619 IEQYSAGHLDML RIKSLQTRVDQI+G+G D+K+RE K ++ E D++SM+GRV Sbjct: 569 IEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSRE---KITAEHETTDDLSMLGRV 625 Query: 620 VKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--SLGAVQVPLFDPDITSDYHSPVDHEDI 677 VKVEKQVQSIE KLD LL Y + LR G+++ +L + Q+P F+ + TSDY SPVD +D+ Sbjct: 626 VKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDL 685 Query: 678 SVSAQTLS-ISRSVSTNM 694 S SAQ +SRS S N+ Sbjct: 686 SGSAQNSGCLSRSTSANI 703 >gi|236461719 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 2 [Homo sapiens] Length = 923 Score = 746 bits (1926), Expect = 0.0 Identities = 409/678 (60%), Positives = 485/678 (71%), Gaps = 92/678 (13%) Query: 37 GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87 GGGG R R+ LLG PL S +S + +YRR+QN++ Sbjct: 70 GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115 Query: 88 YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147 YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+ Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175 Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207 I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235 Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295 Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327 S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355 Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQ 387 EQHRQKHFEKRR PAANLIQ WR Y+ D ++ ATW Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATW--------------------- 393 Query: 388 RARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQR 447 P + H C + ++ K+R+RM S + Sbjct: 394 ------------------------KPHLKALHT------CSPTNQKLSFKERVRMASPRG 423 Query: 448 RTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRL-----KPRTS 502 ++ S+Q A SPS++ E SPTKVQKSWSFNDRTRFR SLRL KP Sbjct: 424 QSIKSRQ--ASVGDRRSPSTDITAEG-SPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVID 480 Query: 503 AEDA-PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDV 561 A+ A +++V +EK QC+++V+D+ P +KTVIR+IRI+KF VAKRKFKETLRPYDVKDV Sbjct: 481 ADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDV 540 Query: 562 IEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGDRKAREKGDKGPSDAEVVDEISMMGRV 619 IEQYSAGHLDML RIKSLQTRVDQI+G+G D+K+RE K ++ E D++SM+GRV Sbjct: 541 IEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSRE---KITAEHETTDDLSMLGRV 597 Query: 620 VKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--SLGAVQVPLFDPDITSDYHSPVDHEDI 677 VKVEKQVQSIE KLD LL Y + LR G+++ +L + Q+P F+ + TSDY SPVD +D+ Sbjct: 598 VKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDL 657 Query: 678 SVSAQTLS-ISRSVSTNM 694 S SAQ +SRS S N+ Sbjct: 658 SGSAQNSGCLSRSTSANI 675 >gi|26051264 potassium voltage-gated channel KQT-like protein 2 isoform a [Homo sapiens] Length = 872 Score = 682 bits (1760), Expect = 0.0 Identities = 371/680 (54%), Positives = 470/680 (69%), Gaps = 53/680 (7%) Query: 38 GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97 G +P+R +L P GA G+G + + YR+LQN++YNVLERPRGW Sbjct: 44 GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91 Query: 98 AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157 AF+YH ++FLLVFSCLVLSV STI+E+++ + L ILE V IVVFG+EY VR+W+AGCC Sbjct: 92 AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151 Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217 CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211 Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277 DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK N F +YAD+LWWG Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271 Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337 ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331 Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYD------------------SILPSFREL 379 RR PAA LIQ+AWR Y+T++SR L +TW YY+ ++P +L Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQL 391 Query: 380 ALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESS-RMGIKD 438 LL ++++G L R+ P P+ +PS+ P C P CPG SS ++ +KD Sbjct: 392 ELL--RNLKSKSG----LAFRKDPPPEPSPSKGSP---CRGP-LCGCCPGRSSQKVSLKD 441 Query: 439 RIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLK 498 R+ S + K T+ SPS++Q E SP+KV KSWSF DR+R R + R+K Sbjct: 442 RV-FSSPRGVAAKGKGSPQAQTVRRSPSADQSLE-DSPSKVPKSWSFGDRSRARQAFRIK 499 Query: 499 ---PRTSAEDA--PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETL 553 R ++E+A P E++ ++KS CE +D+ P +K IR++ +++FLV+KRKFKE+L Sbjct: 500 GAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESL 559 Query: 554 RPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEI 613 RPYDV DVIEQYSAGHLDML RIKSLQ+RVDQIVGRGP + KGP++AE+ ++ Sbjct: 560 RPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPA--ITDKDRTKGPAEAELPEDP 617 Query: 614 SMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVD 673 SMMGR+ KVEKQV S+E KLD L+ Y + R G + +P+ YHSP D Sbjct: 618 SMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAKEPEPAPPYHSPED 675 Query: 674 -HEDISVSAQTLSISRSVST 692 E + + I RS S+ Sbjct: 676 SREHVDRHGCIVKIVRSSSS 695 >gi|26051260 potassium voltage-gated channel KQT-like protein 2 isoform c [Homo sapiens] Length = 844 Score = 672 bits (1733), Expect = 0.0 Identities = 363/669 (54%), Positives = 462/669 (69%), Gaps = 59/669 (8%) Query: 38 GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97 G +P+R +L P GA G+G + + YR+LQN++YNVLERPRGW Sbjct: 44 GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91 Query: 98 AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157 AF+YH ++FLLVFSCLVLSV STI+E+++ + L ILE V IVVFG+EY VR+W+AGCC Sbjct: 92 AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151 Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217 CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211 Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277 DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK N F +YAD+LWWG Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271 Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337 ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331 Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYD--------SILPSFRELALLFEHVQRA 389 RR PAA LIQ+AWR Y+T++SR L +TW YY+ ++P +L LL ++ Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPPLNQLELL--RNLKS 389 Query: 390 RNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRT 449 ++G L R+ P P+ +PS+ ++ +KDR+ S + Sbjct: 390 KSG----LAFRKDPPPEPSPSQ---------------------KVSLKDRV-FSSPRGVA 423 Query: 450 GPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLK---PRTSAEDA 506 K T+ SPS++Q E SP+KV KSWSF DR+R R + R+K R ++E+A Sbjct: 424 AKGKGSPQAQTVRRSPSADQSLE-DSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEA 482 Query: 507 --PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQ 564 P E++ ++KS CE +D+ P +K IR++ +++FLV+KRKFKE+LRPYDV DVIEQ Sbjct: 483 SLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQ 542 Query: 565 YSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEK 624 YSAGHLDML RIKSLQ+RVDQIVGRGP + KGP++AE+ ++ SMMGR+ KVEK Sbjct: 543 YSAGHLDMLSRIKSLQSRVDQIVGRGPA--ITDKDRTKGPAEAELPEDPSMMGRLGKVEK 600 Query: 625 QVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVD-HEDISVSAQT 683 QV S+E KLD L+ Y + R G + +P+ YHSP D E + Sbjct: 601 QVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCI 658 Query: 684 LSISRSVST 692 + I RS S+ Sbjct: 659 VKIVRSSSS 667 >gi|26051262 potassium voltage-gated channel KQT-like protein 2 isoform b [Homo sapiens] Length = 854 Score = 668 bits (1723), Expect = 0.0 Identities = 363/679 (53%), Positives = 462/679 (68%), Gaps = 69/679 (10%) Query: 38 GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97 G +P+R +L P GA G+G + + YR+LQN++YNVLERPRGW Sbjct: 44 GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91 Query: 98 AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157 AF+YH ++FLLVFSCLVLSV STI+E+++ + L ILE V IVVFG+EY VR+W+AGCC Sbjct: 92 AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151 Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217 CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211 Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277 DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK N F +YAD+LWWG Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271 Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337 ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331 Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYD------------------SILPSFREL 379 RR PAA LIQ+AWR Y+T++SR L +TW YY+ ++P +L Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQL 391 Query: 380 ALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDR 439 LL ++++G L R+ P P+ +PS+ ++ +KDR Sbjct: 392 ELL--RNLKSKSG----LAFRKDPPPEPSPSQ---------------------KVSLKDR 424 Query: 440 IRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLK- 498 + S + K T+ SPS++Q E SP+KV KSWSF DR+R R + R+K Sbjct: 425 V-FSSPRGVAAKGKGSPQAQTVRRSPSADQSLE-DSPSKVPKSWSFGDRSRARQAFRIKG 482 Query: 499 --PRTSAEDA--PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLR 554 R ++E+A P E++ ++KS CE +D+ P +K IR++ +++FLV+KRKFKE+LR Sbjct: 483 AASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLR 542 Query: 555 PYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEIS 614 PYDV DVIEQYSAGHLDML RIKSLQ+RVDQIVGRGP + KGP++AE+ ++ S Sbjct: 543 PYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPA--ITDKDRTKGPAEAELPEDPS 600 Query: 615 MMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVD- 673 MMGR+ KVEKQV S+E KLD L+ Y + R G + +P+ YHSP D Sbjct: 601 MMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAKEPEPAPPYHSPEDS 658 Query: 674 HEDISVSAQTLSISRSVST 692 E + + I RS S+ Sbjct: 659 REHVDRHGCIVKIVRSSSS 677 >gi|26051266 potassium voltage-gated channel KQT-like protein 2 isoform d [Homo sapiens] Length = 841 Score = 659 bits (1701), Expect = 0.0 Identities = 359/678 (52%), Positives = 456/678 (67%), Gaps = 80/678 (11%) Query: 38 GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97 G +P+R +L P GA G+G + + YR+LQN++YNVLERPRGW Sbjct: 44 GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91 Query: 98 AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157 AF+YH ++FLLVFSCLVLSV STI+E+++ + L ILE V IVVFG+EY VR+W+AGCC Sbjct: 92 AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151 Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217 CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211 Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277 DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK N F +YAD+LWWG Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271 Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337 ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331 Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYD------------------SILPSFREL 379 RR PAA LIQ+AWR Y+T++SR L +TW YY+ ++P +L Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQL 391 Query: 380 ALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDR 439 LL ++++G L R+ P P+ +PS Sbjct: 392 ELL--RNLKSKSG----LAFRKDPPPEPSPSP---------------------------- 417 Query: 440 IRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKP 499 R +++ + P Q T+ SPS++Q E SP+KV KSWSF DR+R R + R+K Sbjct: 418 -RGVAAKGKGSPQAQ-----TVRRSPSADQSLE-DSPSKVPKSWSFGDRSRARQAFRIKG 470 Query: 500 RTSAEDA----PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRP 555 S +++ P E++ ++KS CE +D+ P +K IR++ +++FLV+KRKFKE+LRP Sbjct: 471 AASRQNSEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRP 530 Query: 556 YDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISM 615 YDV DVIEQYSAGHLDML RIKSLQ+RVDQIVGRGP + KGP++AE+ ++ SM Sbjct: 531 YDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPA--ITDKDRTKGPAEAELPEDPSM 588 Query: 616 MGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVD-H 674 MGR+ KVEKQV S+E KLD L+ Y + R G + +P+ YHSP D Sbjct: 589 MGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAKEPEPAPPYHSPEDSR 646 Query: 675 EDISVSAQTLSISRSVST 692 E + + I RS S+ Sbjct: 647 EHVDRHGCIVKIVRSSSS 664 >gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo sapiens] Length = 872 Score = 559 bits (1441), Expect = e-159 Identities = 319/673 (47%), Positives = 419/673 (62%), Gaps = 109/673 (16%) Query: 7 RRLGLGPPPGDAPRAELVALTAVQSEQG----EAGGGGSPRRLGLLGSPLPPGAPLPGPG 62 R++GL P GD + L AL A + G E GG +R G L PL P Sbjct: 41 RKVGLAP--GDVEQVTL-ALGAGADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPV 97 Query: 63 SGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQ 122 +R++A +YRR+Q +Y+ LERPRGWA +YH +FL+V CL+L+VL+T + Sbjct: 98 --------KRNNA---KYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFK 146 Query: 123 EHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVF 182 E++ ++ + LL+LE I +FG E+ +R+W+AGCCCRY+GW+GR +FARKP C++D V Sbjct: 147 EYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVL 206 Query: 183 VASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAW 242 +ASV V+A G QGN+ ATS LRS+RFLQILRM+RMDRRGGTWKLLGS + AHSKELITAW Sbjct: 207 IASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAW 265 Query: 243 YIGFLVLIFASFLVYLAEKDA----------NSDFSSYADSLWWGTITLTTIGYGDKTPH 292 YIGFL LI +SFLVYL EKD +F +YAD+LWWG ITL TIGYGDKTP Sbjct: 266 YIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPK 325 Query: 293 TWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRL 352 TW GR++AA F+L+G+SFFALPAGILGSG ALKVQEQHRQKHFEKRR PAA LIQAAWR Sbjct: 326 TWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRY 385 Query: 353 YSTDMSRAYLTATWYYYDSIL--PSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPS 410 Y+T+ +R L ATW +Y+S++ P FR+ E ++ A Sbjct: 386 YATNPNRIDLVATWRFYESVVSFPFFRK-----EQLEAA--------------------- 419 Query: 411 RYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQV 470 S ++G+ DR+R+ S R +K L P + + + Sbjct: 420 -------------------SSQKLGLLDRVRL--SNPRGSNTKGKLFTPL-----NVDAI 453 Query: 471 GEATSPTKVQKSWSFNDRTRFRASLRLKPRT---SAEDA-PSEEVAEEKSYQCELTVDDI 526 E SP+K K N++ RFR + R+K S+EDA + +AE++ Y + ++D+ Sbjct: 454 EE--SPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDM 511 Query: 527 MPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQI 586 +P +K IR++RIL+F + K+KFKETLRPYDVKDVIEQYSAGHLDML RIK LQTR+D I Sbjct: 512 IPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMI 571 Query: 587 VGRGPGDRKAREKGDKG-------------------PSDAEVVDEISMMGRVVKVEKQVQ 627 GP +K KG PS +E+ D+ SMMG+ VKVE+QVQ Sbjct: 572 FTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQ-SMMGKFVKVERQVQ 630 Query: 628 SIEHKLDLLLGFY 640 + KLD L+ + Sbjct: 631 DMGKKLDFLVDMH 643 >gi|236462242 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 5 [Homo sapiens] Length = 822 Score = 510 bits (1314), Expect = e-144 Identities = 252/339 (74%), Positives = 281/339 (82%), Gaps = 24/339 (7%) Query: 37 GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87 GGGG R R+ LLG PL S +S + +YRR+QN++ Sbjct: 70 GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115 Query: 88 YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147 YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+ Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175 Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207 I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235 Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295 Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327 S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355 Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATW 366 EQHRQKHFEKRR PAANLIQ WR Y+ D ++ ATW Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATW 393 Score = 182 bits (461), Expect = 1e-45 Identities = 103/164 (62%), Positives = 126/164 (76%), Gaps = 8/164 (4%) Query: 536 SIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGD 593 S RI+KF VAKRKFKETLRPYDVKDVIEQYSAGHLDML RIKSLQTRVDQI+G+G D Sbjct: 414 SSRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSD 473 Query: 594 RKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--S 651 +K+RE K ++ E D++SM+GRVVKVEKQVQSIE KLD LL Y + LR G+++ + Sbjct: 474 KKSRE---KITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALA 530 Query: 652 LGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLS-ISRSVSTNM 694 L + Q+P F+ + TSDY SPVD +D+S SAQ +SRS S N+ Sbjct: 531 LASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANI 574 >gi|26051268 potassium voltage-gated channel KQT-like protein 2 isoform e [Homo sapiens] Length = 393 Score = 482 bits (1240), Expect = e-136 Identities = 231/333 (69%), Positives = 273/333 (81%), Gaps = 12/333 (3%) Query: 38 GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97 G +P+R +L P GA G+G + + YR+LQN++YNVLERPRGW Sbjct: 44 GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91 Query: 98 AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157 AF+YH ++FLLVFSCLVLSV STI+E+++ + L ILE V IVVFG+EY VR+W+AGCC Sbjct: 92 AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151 Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217 CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211 Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277 DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK N F +YAD+LWWG Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271 Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337 ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331 Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYD 370 RR PAA LIQ+AWR Y+T++SR L +TW YY+ Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYE 364 >gi|32479527 potassium voltage-gated channel, KQT-like subfamily, member 1 isoform 1 [Homo sapiens] Length = 676 Score = 397 bits (1021), Expect = e-110 Identities = 264/683 (38%), Positives = 362/683 (53%), Gaps = 125/683 (18%) Query: 2 AEAPPR----RLGLGPPPG----DAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLP 53 A +PPR R G G PG A A+ + +E G AGG L +P+ Sbjct: 4 ASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGA--------LYAPIA 55 Query: 54 PGAPLPGPGSGSGSACGQ----------------RSSAAHKRY-----RRLQNWVYNVLE 92 PGAP P P + + R S R +Q VYN LE Sbjct: 56 PGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLE 115 Query: 93 RPRGW-AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRV 151 RP GW FVYH +FL+V CL+ SVLSTI+++ LA L +E V++V FG EY+VR+ Sbjct: 116 RPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRL 175 Query: 152 WSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQI 211 WSAGC +Y G GR RFARKP +ID IV VAS+ V+ G++G +FATSA+R +RFLQI Sbjct: 176 WSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQI 235 Query: 212 LRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDA-----NSD 266 LRM+ +DR+GGTW+LLGSVV+ H +ELIT YIGFL LIF+S+ VYLAEKDA + Sbjct: 236 LRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVE 295 Query: 267 FSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKV 326 F SYAD+LWWG +T+TTIGYGDK P TW+G+ +A+ F++ ISFFALPAGILGSGFALKV Sbjct: 296 FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKV 355 Query: 327 QEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHV 386 Q++ RQKHF ++ AA+LIQ AWR Y+ + ++TW Y Sbjct: 356 QQKQRQKHFNRQIPAAASLIQTAWRCYAAENPD---SSTWKIY----------------- 395 Query: 387 QRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQ 446 +R+AP H S S P + +K + Sbjct: 396 ------------IRKAP-------------RSHTLLSPS--PKPKKSVVVKKKKFKLDKD 428 Query: 447 RRTGPSKQHLAPPTMPTSPSSEQ-----------VGEATSPTKVQKSWSFNDRTR-FRAS 494 P ++ L P + P E+ SPT ++ S RT F Sbjct: 429 NGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAED 488 Query: 495 LRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLR 554 L L+ T P +++ + + A VIR ++ + VAK+KF++ + Sbjct: 489 LDLEGETLL--TPITHISQLREHH---------RATIKVIRRMQ---YFVAKKKFQQARK 534 Query: 555 PYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG-DKGPSDAEVVDEI 613 PYDV+DVIEQYS GHL+++ RIK LQ R+DQ +G+ EK D+G + Sbjct: 535 PYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSN-------- 586 Query: 614 SMMGRVVKVEKQVQSIEHKLDLL 636 ++ R+ +VE +V ++ +L L+ Sbjct: 587 TIGARLNRVEDKVTQLDQRLALI 609 >gi|32479525 potassium voltage-gated channel, KQT-like subfamily, member 1 isoform 2 [Homo sapiens] Length = 549 Score = 363 bits (932), Expect = e-100 Identities = 223/549 (40%), Positives = 311/549 (56%), Gaps = 87/549 (15%) Query: 106 FLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQG 165 FL+V CL+ SVLSTI+++ LA L +E V++V FG EY+VR+WSAGC +Y G G Sbjct: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62 Query: 166 RFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWK 225 R RFARKP +ID IV VAS+ V+ G++G +FATSA+R +RFLQILRM+ +DR+GGTW+ Sbjct: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122 Query: 226 LLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDA-----NSDFSSYADSLWWGTIT 280 LLGSVV+ H +ELIT YIGFL LIF+S+ VYLAEKDA +F SYAD+LWWG +T Sbjct: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182 Query: 281 LTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRM 340 +TTIGYGDK P TW+G+ +A+ F++ ISFFALPAGILGSGFALKVQ++ RQKHF ++ Sbjct: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242 Query: 341 PAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVR 400 AA+LIQ AWR Y+ + ++TW Y +R Sbjct: 243 AAASLIQTAWRCYAAENPD---SSTWKIY-----------------------------IR 270 Query: 401 RAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPT 460 +AP H S S P + +K + P ++ L P Sbjct: 271 KAP-------------RSHTLLSPS--PKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPH 315 Query: 461 MPTSPSSEQ-----------VGEATSPTKVQKSWSFNDRTR-FRASLRLKPRTSAEDAPS 508 + P E+ SPT ++ S RT F L L+ T P Sbjct: 316 ITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLL--TPI 373 Query: 509 EEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAG 568 +++ + + A VIR ++ + VAK+KF++ +PYDV+DVIEQYS G Sbjct: 374 THISQLREHH---------RATIKVIRRMQ---YFVAKKKFQQARKPYDVRDVIEQYSQG 421 Query: 569 HLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG-DKGPSDAEVVDEISMMGRVVKVEKQVQ 627 HL+++ RIK LQ R+DQ +G+ EK D+G + ++ R+ +VE +V Sbjct: 422 HLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSN--------TIGARLNRVEDKVT 473 Query: 628 SIEHKLDLL 636 ++ +L L+ Sbjct: 474 QLDQRLALI 482 >gi|27436974 potassium voltage-gated channel, Shab-related subfamily, member 2 [Homo sapiens] Length = 911 Score = 99.4 bits (246), Expect = 1e-20 Identities = 79/269 (29%), Positives = 136/269 (50%), Gaps = 26/269 (9%) Query: 87 VYNVLERPRGWA---FVYHVFIFLLVFSCLVLSV--LSTIQEHQELA----NECLLILEF 137 ++++LE+P + V I +V S + LS+ L +QE E N L +E Sbjct: 179 LWDLLEKPNSSVAAKILAIVSILFIVLSTIALSLNTLPELQETDEFGQLNDNRQLAHVEA 238 Query: 138 VMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVAS-VAVIAAGTQGN 196 V I F +EY++R S+ +++F + P VID + + V + + + Sbjct: 239 VCIAWFTMEYLLRFLSS---------PNKWKFFKGPLNVIDLLAILPYYVTIFLTESNKS 289 Query: 197 IFATSALRSM----RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLIF 251 + +R + R ++ILR++++ R + LG + EL + ++ ++IF Sbjct: 290 VLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIF 349 Query: 252 ASFLVYLAEKDANSD-FSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISF 310 +S LV+ AEKD ++ F+S S WW TIT+TT+GYGD P T LG+++ + G+ Sbjct: 350 SS-LVFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLV 408 Query: 311 FALPAGILGSGFALKVQEQHRQKHFEKRR 339 ALP I+ + F+ +EQ RQ+ KRR Sbjct: 409 IALPIPIIVNNFSEFYKEQKRQEKAIKRR 437 >gi|4826784 potassium voltage-gated channel, Shab-related subfamily, member 1 [Homo sapiens] Length = 858 Score = 95.9 bits (237), Expect = 1e-19 Identities = 78/270 (28%), Positives = 135/270 (50%), Gaps = 28/270 (10%) Query: 87 VYNVLERPRGWA---FVYHVFIFLLVFSCLVLSVLSTIQEHQELA-------NECLLILE 136 ++++LE+P + + I +V S + LS L+T+ E Q L N L +E Sbjct: 175 LWDLLEKPNSSVAAKILAIISIMFIVLSTIALS-LNTLPELQSLDEFGQSTDNPQLAHVE 233 Query: 137 FVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVAS-VAVIAAGTQG 195 V I F +EY++R S+ +++F + P ID + + V + + Sbjct: 234 AVCIAWFTMEYLLRFLSS---------PKKWKFFKGPLNAIDLLAILPYYVTIFLTESNK 284 Query: 196 NIFATSALRSM----RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLI 250 ++ +R + R ++ILR++++ R + LG + EL + ++ ++I Sbjct: 285 SVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMI 344 Query: 251 FASFLVYLAEKDAN-SDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGIS 309 F+S LV+ AEKD + + F S S WW TIT+TT+GYGD P T LG+++ + G+ Sbjct: 345 FSS-LVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVL 403 Query: 310 FFALPAGILGSGFALKVQEQHRQKHFEKRR 339 ALP I+ + F+ +EQ RQ+ KRR Sbjct: 404 VIALPIPIIVNNFSEFYKEQKRQEKAIKRR 433 >gi|21217561 Shaw-related voltage-gated potassium channel protein 2 isoform KV3.2a [Homo sapiens] Length = 613 Score = 90.9 bits (224), Expect = 4e-18 Identities = 80/318 (25%), Positives = 141/318 (44%), Gaps = 63/318 (19%) Query: 43 RRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERP---RGWAF 99 +RLG+ A L GP SG R+RRLQ ++ + E P R F Sbjct: 188 KRLGI-----EDAAGLGGPDGKSG------------RWRRLQPRMWALFEDPYSSRAARF 230 Query: 100 VYHVFIFLLVFS----CL---------------VLSVLSTIQEHQELANECLLILEFVMI 140 + +F ++ S CL V++ S + +++ + L +E V + Sbjct: 231 IAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCV 290 Query: 141 VVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV---FVASVAVIAAGTQGNI 197 V F E++VR+ + + F + +IDF+ F V + ++ Sbjct: 291 VWFTFEFLVRIVFS---------PNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAK 341 Query: 198 FATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIGFLVLIFASFLV 256 LR +RF++ILR+ ++ R ++LG + A + E L+ ++ VLIFA+ ++ Sbjct: 342 DVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFAT-MI 400 Query: 257 YLAEK----------DANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALL 306 Y AE+ ++ F + WW +T+TT+GYGD P TW G ++ A AL Sbjct: 401 YYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALA 460 Query: 307 GISFFALPAGILGSGFAL 324 G+ A+P ++ + F + Sbjct: 461 GVLTIAMPVPVIVNNFGM 478 >gi|21217563 Shaw-related voltage-gated potassium channel protein 2 isoform KV3.2b [Homo sapiens] Length = 638 Score = 90.9 bits (224), Expect = 4e-18 Identities = 80/318 (25%), Positives = 141/318 (44%), Gaps = 63/318 (19%) Query: 43 RRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERP---RGWAF 99 +RLG+ A L GP SG R+RRLQ ++ + E P R F Sbjct: 188 KRLGI-----EDAAGLGGPDGKSG------------RWRRLQPRMWALFEDPYSSRAARF 230 Query: 100 VYHVFIFLLVFS----CL---------------VLSVLSTIQEHQELANECLLILEFVMI 140 + +F ++ S CL V++ S + +++ + L +E V + Sbjct: 231 IAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCV 290 Query: 141 VVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV---FVASVAVIAAGTQGNI 197 V F E++VR+ + + F + +IDF+ F V + ++ Sbjct: 291 VWFTFEFLVRIVFS---------PNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAK 341 Query: 198 FATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIGFLVLIFASFLV 256 LR +RF++ILR+ ++ R ++LG + A + E L+ ++ VLIFA+ ++ Sbjct: 342 DVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFAT-MI 400 Query: 257 YLAEK----------DANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALL 306 Y AE+ ++ F + WW +T+TT+GYGD P TW G ++ A AL Sbjct: 401 YYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALA 460 Query: 307 GISFFALPAGILGSGFAL 324 G+ A+P ++ + F + Sbjct: 461 GVLTIAMPVPVIVNNFGM 478 >gi|24497458 Shaw-related voltage-gated potassium channel protein 2 isoform KV3.2c [Homo sapiens] Length = 558 Score = 90.9 bits (224), Expect = 4e-18 Identities = 80/318 (25%), Positives = 141/318 (44%), Gaps = 63/318 (19%) Query: 43 RRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERP---RGWAF 99 +RLG+ A L GP SG R+RRLQ ++ + E P R F Sbjct: 188 KRLGI-----EDAAGLGGPDGKSG------------RWRRLQPRMWALFEDPYSSRAARF 230 Query: 100 VYHVFIFLLVFS----CL---------------VLSVLSTIQEHQELANECLLILEFVMI 140 + +F ++ S CL V++ S + +++ + L +E V + Sbjct: 231 IAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCV 290 Query: 141 VVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV---FVASVAVIAAGTQGNI 197 V F E++VR+ + + F + +IDF+ F V + ++ Sbjct: 291 VWFTFEFLVRIVFS---------PNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAK 341 Query: 198 FATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIGFLVLIFASFLV 256 LR +RF++ILR+ ++ R ++LG + A + E L+ ++ VLIFA+ ++ Sbjct: 342 DVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFAT-MI 400 Query: 257 YLAEK----------DANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALL 306 Y AE+ ++ F + WW +T+TT+GYGD P TW G ++ A AL Sbjct: 401 YYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALA 460 Query: 307 GISFFALPAGILGSGFAL 324 G+ A+P ++ + F + Sbjct: 461 GVLTIAMPVPVIVNNFGM 478 >gi|88758576 Shaw-related voltage-gated potassium channel protein 4 isoform c [Homo sapiens] Length = 626 Score = 90.5 bits (223), Expect = 5e-18 Identities = 86/351 (24%), Positives = 155/351 (44%), Gaps = 51/351 (14%) Query: 25 ALTAVQSEQGEAGGGGSPRRLG-----LLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKR 79 AL +S G G G G L L P G G+GSG G + + Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQP----RM 212 Query: 80 YRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCL--------------VLSV--LSTIQE 123 + ++ + R +A ++ + + + F CL +L V ++++ Sbjct: 213 WALFEDPYSSRAARVVAFASLFFILVSITTF-CLETHEAFNIDRNVTEILRVGNITSVHF 271 Query: 124 HQELANECLLI-LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV- 181 +E+ E +L +E V ++ F LE++VR+ CC F + +IDF+ Sbjct: 272 RREVETEPILTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAI 322 Query: 182 --FVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-L 238 F V + ++ LR +RF++ILR+ ++ R ++LG + A + E L Sbjct: 323 LPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFL 382 Query: 239 ITAWYIGFLVLIFASFLVYLAEK----------DANSDFSSYADSLWWGTITLTTIGYGD 288 + ++ VLIFA+ ++Y AE+ + ++DF + WW +T+TT+GYGD Sbjct: 383 LLIIFLALGVLIFAT-MIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGD 441 Query: 289 KTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRR 339 P TW G ++ A AL G+ A+P ++ + F + ++ K+R Sbjct: 442 MYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492 >gi|24497462 Shaw-related voltage-gated potassium channel protein 4 isoform a [Homo sapiens] Length = 635 Score = 90.5 bits (223), Expect = 5e-18 Identities = 86/351 (24%), Positives = 155/351 (44%), Gaps = 51/351 (14%) Query: 25 ALTAVQSEQGEAGGGGSPRRLG-----LLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKR 79 AL +S G G G G L L P G G+GSG G + + Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQP----RM 212 Query: 80 YRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCL--------------VLSV--LSTIQE 123 + ++ + R +A ++ + + + F CL +L V ++++ Sbjct: 213 WALFEDPYSSRAARVVAFASLFFILVSITTF-CLETHEAFNIDRNVTEILRVGNITSVHF 271 Query: 124 HQELANECLLI-LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV- 181 +E+ E +L +E V ++ F LE++VR+ CC F + +IDF+ Sbjct: 272 RREVETEPILTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAI 322 Query: 182 --FVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-L 238 F V + ++ LR +RF++ILR+ ++ R ++LG + A + E L Sbjct: 323 LPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFL 382 Query: 239 ITAWYIGFLVLIFASFLVYLAEK----------DANSDFSSYADSLWWGTITLTTIGYGD 288 + ++ VLIFA+ ++Y AE+ + ++DF + WW +T+TT+GYGD Sbjct: 383 LLIIFLALGVLIFAT-MIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGD 441 Query: 289 KTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRR 339 P TW G ++ A AL G+ A+P ++ + F + ++ K+R Sbjct: 442 MYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492 >gi|24497464 Shaw-related voltage-gated potassium channel protein 4 isoform b [Homo sapiens] Length = 582 Score = 90.5 bits (223), Expect = 5e-18 Identities = 86/351 (24%), Positives = 155/351 (44%), Gaps = 51/351 (14%) Query: 25 ALTAVQSEQGEAGGGGSPRRLG-----LLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKR 79 AL +S G G G G L L P G G+GSG G + + Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQP----RM 212 Query: 80 YRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCL--------------VLSV--LSTIQE 123 + ++ + R +A ++ + + + F CL +L V ++++ Sbjct: 213 WALFEDPYSSRAARVVAFASLFFILVSITTF-CLETHEAFNIDRNVTEILRVGNITSVHF 271 Query: 124 HQELANECLLI-LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV- 181 +E+ E +L +E V ++ F LE++VR+ CC F + +IDF+ Sbjct: 272 RREVETEPILTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAI 322 Query: 182 --FVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-L 238 F V + ++ LR +RF++ILR+ ++ R ++LG + A + E L Sbjct: 323 LPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFL 382 Query: 239 ITAWYIGFLVLIFASFLVYLAEK----------DANSDFSSYADSLWWGTITLTTIGYGD 288 + ++ VLIFA+ ++Y AE+ + ++DF + WW +T+TT+GYGD Sbjct: 383 LLIIFLALGVLIFAT-MIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGD 441 Query: 289 KTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRR 339 P TW G ++ A AL G+ A+P ++ + F + ++ K+R Sbjct: 442 MYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492 >gi|6912444 potassium voltage-gated channel, subfamily G, member 2 [Homo sapiens] Length = 466 Score = 90.1 bits (222), Expect = 6e-18 Identities = 99/345 (28%), Positives = 144/345 (41%), Gaps = 46/345 (13%) Query: 17 DAPRAELVALTAVQSEQGEAGGG-GSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSA 75 D R E L ++ + EA P G GSP A G R Sbjct: 111 DEARLERCCLRRLRRREEEAAEARAGPTERGAQGSP--------------ARALGPRGRL 156 Query: 76 AHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSC-LVLSVLSTIQEHQELANEC--- 131 R RRL++ V N G F F+ V + L LS + I+ +E EC Sbjct: 157 QRGR-RRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEE-RGECSPK 214 Query: 132 ---LLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV----FVA 184 L +LE V + F E+++R A C F R P +ID + +V+ Sbjct: 215 CRSLFVLETVCVAWFSFEFLLRSLQAESKCA---------FLRAPLNIIDILALLPFYVS 265 Query: 185 SVAVIAAGTQGNIFATSA---LRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITA 241 + +AAG G A LR +R L++L ++R+ R + LG + ++E Sbjct: 266 LLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREF--G 323 Query: 242 WYIGFLVLIFASF--LVYLAEKD--ANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGR 297 + FL + A F LV+LAE++ A DFSS S WW I++TT+GYGD P + G+ Sbjct: 324 LLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQ 383 Query: 298 VLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPA 342 V+A L GI A P + F+ E Q+ PA Sbjct: 384 VVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPA 428 >gi|27436984 potassium voltage-gated channel, Shal-related subfamily, member 3 isoform 1 [Homo sapiens] Length = 655 Score = 88.2 bits (217), Expect = 2e-17 Identities = 59/229 (25%), Positives = 112/229 (48%), Gaps = 16/229 (6%) Query: 135 LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQ 194 L+ +++F +EY++R+++A R+RF R +ID + + I Sbjct: 229 LDTACVMIFTVEYLLRLFAA---------PSRYRFIRSVMSIIDVVAIMPYY--IGLVMT 277 Query: 195 GNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLIFAS 253 N + A ++R ++ R+ + R ++LG + + + EL + + ++IFA+ Sbjct: 278 NNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFAT 337 Query: 254 FLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFAL 313 + Y + + S F+S S W+ +T+TT+GYGD P T G++ + +L G+ AL Sbjct: 338 VMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIAL 397 Query: 314 PAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYL 362 P ++ S F+ + H+ + +KRR + A R+ T S AYL Sbjct: 398 PVPVIVSNFS---RIYHQNQRADKRRAQKKARL-ARIRVAKTGSSNAYL 442 >gi|27436986 potassium voltage-gated channel, Shal-related subfamily, member 3 isoform 2 [Homo sapiens] Length = 636 Score = 88.2 bits (217), Expect = 2e-17 Identities = 59/229 (25%), Positives = 112/229 (48%), Gaps = 16/229 (6%) Query: 135 LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQ 194 L+ +++F +EY++R+++A R+RF R +ID + + I Sbjct: 229 LDTACVMIFTVEYLLRLFAA---------PSRYRFIRSVMSIIDVVAIMPYY--IGLVMT 277 Query: 195 GNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLIFAS 253 N + A ++R ++ R+ + R ++LG + + + EL + + ++IFA+ Sbjct: 278 NNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFAT 337 Query: 254 FLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFAL 313 + Y + + S F+S S W+ +T+TT+GYGD P T G++ + +L G+ AL Sbjct: 338 VMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIAL 397 Query: 314 PAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYL 362 P ++ S F+ + H+ + +KRR + A R+ T S AYL Sbjct: 398 PVPVIVSNFS---RIYHQNQRADKRRAQKKARL-ARIRVAKTGSSNAYL 442 >gi|88758565 potassium voltage-gated channel, shaker-related subfamily, member 3 [Homo sapiens] Length = 575 Score = 87.4 bits (215), Expect = 4e-17 Identities = 56/196 (28%), Positives = 97/196 (49%), Gaps = 16/196 (8%) Query: 134 ILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIA--- 190 ++E + I+ F E +VR ++ + F+R +ID + + + Sbjct: 297 VVETLCIIWFSFELLVRFFAC---------PSKATFSRNIMNLIDIVAIIPYFITLGTEL 347 Query: 191 AGTQGN---IFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFL 247 A QGN + + LR +R +++ R+ ++ R ++LG + A +EL + F+ Sbjct: 348 AERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFI 407 Query: 248 VLIFASFLVYLAEKD-ANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALL 306 +I S VY AE D S FSS D+ WW +T+TT+GYGD P T G+++ + A+ Sbjct: 408 GVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIA 467 Query: 307 GISFFALPAGILGSGF 322 G+ ALP ++ S F Sbjct: 468 GVLTIALPVPVIVSNF 483 >gi|119395748 potassium voltage-gated channel subfamily A member 1 [Homo sapiens] Length = 495 Score = 86.7 bits (213), Expect = 7e-17 Identities = 57/207 (27%), Positives = 105/207 (50%), Gaps = 6/207 (2%) Query: 119 STIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVID 178 +T+ + + + I+E + I+ F E +VR ++ C + ++ F +I Sbjct: 208 TTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFA--CPSKTDFFKNIMNFI-DIVAIIP 264 Query: 179 FIVFVASVAVIAAGTQGNIFATSA--LRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSK 236 + + + + G Q ATS LR +R +++ R+ ++ R ++LG + A + Sbjct: 265 YFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMR 324 Query: 237 ELITAWYIGFLVLIFASFLVYLAE-KDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWL 295 EL + F+ +I S VY AE ++A S FSS D+ WW +++TT+GYGD P T Sbjct: 325 ELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIG 384 Query: 296 GRVLAAGFALLGISFFALPAGILGSGF 322 G+++ + A+ G+ ALP ++ S F Sbjct: 385 GKIVGSLCAIAGVLTIALPVPVIVSNF 411 >gi|20070166 potassium voltage-gated channel, subfamily F, member 1 [Homo sapiens] Length = 494 Score = 86.3 bits (212), Expect = 9e-17 Identities = 73/255 (28%), Positives = 117/255 (45%), Gaps = 24/255 (9%) Query: 75 AAHKRYRRLQNWVYNVLERPRGW--AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANE-- 130 AA R+RR Q V+ LE+P A V V FLL+ V+ + TI E Q L E Sbjct: 156 AAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQVLDAEGN 215 Query: 131 -----CLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV---F 182 L +E I F LEY++R++S+ + FA ++D + F Sbjct: 216 RVEHPTLENVETACIGWFTLEYLLRLFSS---------PNKLHFALSFMNIVDVLAILPF 266 Query: 183 VASVAVIAAGTQGNIFAT--SALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-I 239 S+ + G + A++++R ++I R+ ++ R + L + KEL + Sbjct: 267 YVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGL 326 Query: 240 TAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVL 299 Y+ + +F++ + + + F S S WW IT+TT+GYGD P T LG++ Sbjct: 327 LLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLN 386 Query: 300 AAGFALLGISFFALP 314 AA L G+ ALP Sbjct: 387 AAISFLCGVIAIALP 401 >gi|4504817 potassium voltage-gated channel, shaker-related subfamily, member 4 [Homo sapiens] Length = 653 Score = 85.5 bits (210), Expect = 2e-16 Identities = 59/233 (25%), Positives = 105/233 (45%), Gaps = 23/233 (9%) Query: 129 NECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAV 188 N+ I+E V IV F E++VR ++ + F + +ID + + Sbjct: 368 NDPFFIVETVCIVWFSFEFVVRCFAC---------PSQALFFKNIMNIIDIVSILPYFIT 418 Query: 189 IAA----------GTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL 238 + G Q + + LR +R +++ R+ ++ R ++LG + A +EL Sbjct: 419 LGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMREL 478 Query: 239 ITAWYIGFLVLIFASFLVYLAEKDA-NSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGR 297 + F+ +I S VY AE D + F S D+ WW +T+TT+GYGD P T G+ Sbjct: 479 GLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGK 538 Query: 298 VLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAW 350 ++ + A+ G+ ALP ++ S F HR+ E++ N + + Sbjct: 539 IVGSLCAIAGVLTIALPVPVIVSNFN---YFYHRETENEEQTQLTQNAVSCPY 588 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.136 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,444,531 Number of Sequences: 37866 Number of extensions: 1461805 Number of successful extensions: 11786 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 162 Number of HSP's successfully gapped in prelim test: 210 Number of HSP's that attempted gapping in prelim test: 7933 Number of HSP's gapped (non-prelim): 3699 length of query: 695 length of database: 18,247,518 effective HSP length: 109 effective length of query: 586 effective length of database: 14,120,124 effective search space: 8274392664 effective search space used: 8274392664 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.