Search of human proteins with 26638653

Search of human proteins with 26638653

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|26638653 potassium voltage-gated channel KQT-like protein 4
isoform a [Homo sapiens]
         (695 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|26638653 potassium voltage-gated channel KQT-like protein 4 i...  1395   0.0  
gi|26638655 potassium voltage-gated channel KQT-like protein 4 i...  1233   0.0  
gi|28373065 potassium voltage-gated channel, KQT-like subfamily,...   748   0.0  
gi|236461942 potassium voltage-gated channel, KQT-like subfamily...   748   0.0  
gi|236462079 potassium voltage-gated channel, KQT-like subfamily...   747   0.0  
gi|236461719 potassium voltage-gated channel, KQT-like subfamily...   746   0.0  
gi|26051264 potassium voltage-gated channel KQT-like protein 2 i...   682   0.0  
gi|26051260 potassium voltage-gated channel KQT-like protein 2 i...   672   0.0  
gi|26051262 potassium voltage-gated channel KQT-like protein 2 i...   668   0.0  
gi|26051266 potassium voltage-gated channel KQT-like protein 2 i...   659   0.0  
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H...   559   e-159
gi|236462242 potassium voltage-gated channel, KQT-like subfamily...   510   e-144
gi|26051268 potassium voltage-gated channel KQT-like protein 2 i...   482   e-136
gi|32479527 potassium voltage-gated channel, KQT-like subfamily,...   397   e-110
gi|32479525 potassium voltage-gated channel, KQT-like subfamily,...   363   e-100
gi|27436974 potassium voltage-gated channel, Shab-related subfam...    99   1e-20
gi|4826784 potassium voltage-gated channel, Shab-related subfami...    96   1e-19
gi|21217561 Shaw-related voltage-gated potassium channel protein...    91   4e-18
gi|21217563 Shaw-related voltage-gated potassium channel protein...    91   4e-18
gi|24497458 Shaw-related voltage-gated potassium channel protein...    91   4e-18
gi|88758576 Shaw-related voltage-gated potassium channel protein...    91   5e-18
gi|24497462 Shaw-related voltage-gated potassium channel protein...    91   5e-18
gi|24497464 Shaw-related voltage-gated potassium channel protein...    91   5e-18
gi|6912444 potassium voltage-gated channel, subfamily G, member ...    90   6e-18
gi|27436984 potassium voltage-gated channel, Shal-related subfam...    88   2e-17
gi|27436986 potassium voltage-gated channel, Shal-related subfam...    88   2e-17
gi|88758565 potassium voltage-gated channel, shaker-related subf...    87   4e-17
gi|119395748 potassium voltage-gated channel subfamily A member ...    87   7e-17
gi|20070166 potassium voltage-gated channel, subfamily F, member...    86   9e-17
gi|4504817 potassium voltage-gated channel, shaker-related subfa...    86   2e-16

>gi|26638653 potassium voltage-gated channel KQT-like protein 4
           isoform a [Homo sapiens]
          Length = 695

 Score = 1395 bits (3611), Expect = 0.0
 Identities = 695/695 (100%), Positives = 695/695 (100%)

Query: 1   MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG 60
           MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG
Sbjct: 1   MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG 60

Query: 61  PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST 120
           PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST
Sbjct: 61  PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST 120

Query: 121 IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI 180
           IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI
Sbjct: 121 IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI 180

Query: 181 VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT 240
           VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT
Sbjct: 181 VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT 240

Query: 241 AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA 300
           AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA
Sbjct: 241 AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA 300

Query: 301 AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA 360
           AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA
Sbjct: 301 AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA 360

Query: 361 YLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHR 420
           YLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHR
Sbjct: 361 YLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHR 420

Query: 421 PGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ 480
           PGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ
Sbjct: 421 PGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ 480

Query: 481 KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL 540
           KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL
Sbjct: 481 KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL 540

Query: 541 KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG 600
           KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG
Sbjct: 541 KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG 600

Query: 601 DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF 660
           DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF
Sbjct: 601 DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF 660

Query: 661 DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD 695
           DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD
Sbjct: 661 DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD 695


>gi|26638655 potassium voltage-gated channel KQT-like protein 4
           isoform b [Homo sapiens]
          Length = 641

 Score = 1233 bits (3189), Expect = 0.0
 Identities = 631/695 (90%), Positives = 634/695 (91%), Gaps = 54/695 (7%)

Query: 1   MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG 60
           MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG
Sbjct: 1   MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPG 60

Query: 61  PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST 120
           PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST
Sbjct: 61  PGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLST 120

Query: 121 IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI 180
           IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI
Sbjct: 121 IQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFI 180

Query: 181 VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT 240
           VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT
Sbjct: 181 VFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELIT 240

Query: 241 AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA 300
           AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA
Sbjct: 241 AWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLA 300

Query: 301 AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA 360
           AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA
Sbjct: 301 AGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRA 360

Query: 361 YLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHR 420
           YLTATWYYYDSILPSF     + + +                                  
Sbjct: 361 YLTATWYYYDSILPSFSSRMGIKDRI---------------------------------- 386

Query: 421 PGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ 480
                       RMG        SSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ
Sbjct: 387 ------------RMG--------SSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQ 426

Query: 481 KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL 540
           KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL
Sbjct: 427 KSWSFNDRTRFRASLRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRIL 486

Query: 541 KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG 600
           KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG
Sbjct: 487 KFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG 546

Query: 601 DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF 660
           DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF
Sbjct: 547 DKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLF 606

Query: 661 DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD 695
           DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD
Sbjct: 607 DPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD 641


>gi|28373065 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 1 [Homo sapiens]
          Length = 932

 Score =  748 bits (1932), Expect = 0.0
 Identities = 412/681 (60%), Positives = 488/681 (71%), Gaps = 89/681 (13%)

Query: 37  GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87
           GGGG  R         R+ LLG PL              S    +S   + +YRR+QN++
Sbjct: 70  GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115

Query: 88  YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147
           YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+
Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175

Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207
           I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R
Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235

Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267
           FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F
Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295

Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327
           S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ
Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355

Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQ 387
           EQHRQKHFEKRR PAANLIQ  WR Y+ D  ++   ATW                     
Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATW--------------------- 393

Query: 388 RARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESS---RMGIKDRIRMGS 444
                                    P +   H    T    GE+S   ++  K+R+RM S
Sbjct: 394 ------------------------KPHLKALHTCSPTKKEQGEASSSQKLSFKERVRMAS 429

Query: 445 SQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRL-----KP 499
            + ++  S+Q  A      SPS++   E  SPTKVQKSWSFNDRTRFR SLRL     KP
Sbjct: 430 PRGQSIKSRQ--ASVGDRRSPSTDITAEG-SPTKVQKSWSFNDRTRFRPSLRLKSSQPKP 486

Query: 500 RTSAEDA-PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDV 558
              A+ A  +++V +EK  QC+++V+D+ P +KTVIR+IRI+KF VAKRKFKETLRPYDV
Sbjct: 487 VIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDV 546

Query: 559 KDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGDRKAREKGDKGPSDAEVVDEISMM 616
           KDVIEQYSAGHLDML RIKSLQTRVDQI+G+G    D+K+RE   K  ++ E  D++SM+
Sbjct: 547 KDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSRE---KITAEHETTDDLSML 603

Query: 617 GRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--SLGAVQVPLFDPDITSDYHSPVDH 674
           GRVVKVEKQVQSIE KLD LL  Y + LR G+++  +L + Q+P F+ + TSDY SPVD 
Sbjct: 604 GRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDS 663

Query: 675 EDISVSAQTLS-ISRSVSTNM 694
           +D+S SAQ    +SRS S N+
Sbjct: 664 KDLSGSAQNSGCLSRSTSANI 684


>gi|236461942 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 3 [Homo sapiens]
          Length = 942

 Score =  748 bits (1931), Expect = 0.0
 Identities = 411/678 (60%), Positives = 491/678 (72%), Gaps = 73/678 (10%)

Query: 37  GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87
           GGGG  R         R+ LLG PL              S    +S   + +YRR+QN++
Sbjct: 70  GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115

Query: 88  YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147
           YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+
Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175

Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207
           I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R
Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235

Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267
           FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F
Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295

Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327
           S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ
Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355

Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQ 387
           EQHRQKHFEKRR PAANLIQ  WR Y+ D  ++   ATW  +   L +         + Q
Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATWKPHLKALHTCSPTNKFCSNKQ 414

Query: 388 RARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQR 447
           +      R    R+                            +S ++  K+R+RM S + 
Sbjct: 415 KL----FRMYTSRK----------------------------QSQKLSFKERVRMASPRG 442

Query: 448 RTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRL-----KPRTS 502
           ++  S+Q  A      SPS++   E  SPTKVQKSWSFNDRTRFR SLRL     KP   
Sbjct: 443 QSIKSRQ--ASVGDRRSPSTDITAEG-SPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVID 499

Query: 503 AEDA-PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDV 561
           A+ A  +++V +EK  QC+++V+D+ P +KTVIR+IRI+KF VAKRKFKETLRPYDVKDV
Sbjct: 500 ADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDV 559

Query: 562 IEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGDRKAREKGDKGPSDAEVVDEISMMGRV 619
           IEQYSAGHLDML RIKSLQTRVDQI+G+G    D+K+RE   K  ++ E  D++SM+GRV
Sbjct: 560 IEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSRE---KITAEHETTDDLSMLGRV 616

Query: 620 VKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--SLGAVQVPLFDPDITSDYHSPVDHEDI 677
           VKVEKQVQSIE KLD LL  Y + LR G+++  +L + Q+P F+ + TSDY SPVD +D+
Sbjct: 617 VKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDL 676

Query: 678 SVSAQTLS-ISRSVSTNM 694
           S SAQ    +SRS S N+
Sbjct: 677 SGSAQNSGCLSRSTSANI 694


>gi|236462079 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 4 [Homo sapiens]
          Length = 951

 Score =  747 bits (1929), Expect = 0.0
 Identities = 409/678 (60%), Positives = 492/678 (72%), Gaps = 64/678 (9%)

Query: 37  GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87
           GGGG  R         R+ LLG PL              S    +S   + +YRR+QN++
Sbjct: 70  GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115

Query: 88  YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147
           YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+
Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175

Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207
           I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R
Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235

Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267
           FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F
Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295

Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327
           S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ
Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355

Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQ 387
           EQHRQKHFEKRR PAANLIQ  WR Y+ D  ++   ATW                     
Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATW--------------------- 393

Query: 388 RARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQR 447
           +     L      +    + + S++   +   +         +S ++  K+R+RM S + 
Sbjct: 394 KPHLKALHTCSPTKKEQGEASSSKF--CSNKQKLFRMYTSRKQSQKLSFKERVRMASPRG 451

Query: 448 RTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRL-----KPRTS 502
           ++  S+Q  A      SPS++   E  SPTKVQKSWSFNDRTRFR SLRL     KP   
Sbjct: 452 QSIKSRQ--ASVGDRRSPSTDITAEG-SPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVID 508

Query: 503 AEDA-PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDV 561
           A+ A  +++V +EK  QC+++V+D+ P +KTVIR+IRI+KF VAKRKFKETLRPYDVKDV
Sbjct: 509 ADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDV 568

Query: 562 IEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGDRKAREKGDKGPSDAEVVDEISMMGRV 619
           IEQYSAGHLDML RIKSLQTRVDQI+G+G    D+K+RE   K  ++ E  D++SM+GRV
Sbjct: 569 IEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSRE---KITAEHETTDDLSMLGRV 625

Query: 620 VKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--SLGAVQVPLFDPDITSDYHSPVDHEDI 677
           VKVEKQVQSIE KLD LL  Y + LR G+++  +L + Q+P F+ + TSDY SPVD +D+
Sbjct: 626 VKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDL 685

Query: 678 SVSAQTLS-ISRSVSTNM 694
           S SAQ    +SRS S N+
Sbjct: 686 SGSAQNSGCLSRSTSANI 703


>gi|236461719 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 2 [Homo sapiens]
          Length = 923

 Score =  746 bits (1926), Expect = 0.0
 Identities = 409/678 (60%), Positives = 485/678 (71%), Gaps = 92/678 (13%)

Query: 37  GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87
           GGGG  R         R+ LLG PL              S    +S   + +YRR+QN++
Sbjct: 70  GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115

Query: 88  YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147
           YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+
Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175

Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207
           I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R
Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235

Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267
           FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F
Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295

Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327
           S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ
Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355

Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQ 387
           EQHRQKHFEKRR PAANLIQ  WR Y+ D  ++   ATW                     
Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATW--------------------- 393

Query: 388 RARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQR 447
                                    P +   H       C   + ++  K+R+RM S + 
Sbjct: 394 ------------------------KPHLKALHT------CSPTNQKLSFKERVRMASPRG 423

Query: 448 RTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRL-----KPRTS 502
           ++  S+Q  A      SPS++   E  SPTKVQKSWSFNDRTRFR SLRL     KP   
Sbjct: 424 QSIKSRQ--ASVGDRRSPSTDITAEG-SPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVID 480

Query: 503 AEDA-PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDV 561
           A+ A  +++V +EK  QC+++V+D+ P +KTVIR+IRI+KF VAKRKFKETLRPYDVKDV
Sbjct: 481 ADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDV 540

Query: 562 IEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGDRKAREKGDKGPSDAEVVDEISMMGRV 619
           IEQYSAGHLDML RIKSLQTRVDQI+G+G    D+K+RE   K  ++ E  D++SM+GRV
Sbjct: 541 IEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSRE---KITAEHETTDDLSMLGRV 597

Query: 620 VKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--SLGAVQVPLFDPDITSDYHSPVDHEDI 677
           VKVEKQVQSIE KLD LL  Y + LR G+++  +L + Q+P F+ + TSDY SPVD +D+
Sbjct: 598 VKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDL 657

Query: 678 SVSAQTLS-ISRSVSTNM 694
           S SAQ    +SRS S N+
Sbjct: 658 SGSAQNSGCLSRSTSANI 675


>gi|26051264 potassium voltage-gated channel KQT-like protein 2
           isoform a [Homo sapiens]
          Length = 872

 Score =  682 bits (1760), Expect = 0.0
 Identities = 371/680 (54%), Positives = 470/680 (69%), Gaps = 53/680 (7%)

Query: 38  GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97
           G  +P+R  +L  P   GA       G+G     +    +  YR+LQN++YNVLERPRGW
Sbjct: 44  GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91

Query: 98  AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157
           AF+YH ++FLLVFSCLVLSV STI+E+++ +   L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 92  AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151

Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217
           CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211

Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277
           DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK  N  F +YAD+LWWG
Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271

Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337
            ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331

Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYD------------------SILPSFREL 379
           RR PAA LIQ+AWR Y+T++SR  L +TW YY+                   ++P   +L
Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQL 391

Query: 380 ALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESS-RMGIKD 438
            LL     ++++G    L  R+ P P+ +PS+  P   C  P     CPG SS ++ +KD
Sbjct: 392 ELL--RNLKSKSG----LAFRKDPPPEPSPSKGSP---CRGP-LCGCCPGRSSQKVSLKD 441

Query: 439 RIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLK 498
           R+   S +      K      T+  SPS++Q  E  SP+KV KSWSF DR+R R + R+K
Sbjct: 442 RV-FSSPRGVAAKGKGSPQAQTVRRSPSADQSLE-DSPSKVPKSWSFGDRSRARQAFRIK 499

Query: 499 ---PRTSAEDA--PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETL 553
               R ++E+A  P E++ ++KS  CE   +D+ P +K  IR++ +++FLV+KRKFKE+L
Sbjct: 500 GAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESL 559

Query: 554 RPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEI 613
           RPYDV DVIEQYSAGHLDML RIKSLQ+RVDQIVGRGP      +   KGP++AE+ ++ 
Sbjct: 560 RPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPA--ITDKDRTKGPAEAELPEDP 617

Query: 614 SMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVD 673
           SMMGR+ KVEKQV S+E KLD L+  Y +  R G   +         +P+    YHSP D
Sbjct: 618 SMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAKEPEPAPPYHSPED 675

Query: 674 -HEDISVSAQTLSISRSVST 692
             E +      + I RS S+
Sbjct: 676 SREHVDRHGCIVKIVRSSSS 695


>gi|26051260 potassium voltage-gated channel KQT-like protein 2
           isoform c [Homo sapiens]
          Length = 844

 Score =  672 bits (1733), Expect = 0.0
 Identities = 363/669 (54%), Positives = 462/669 (69%), Gaps = 59/669 (8%)

Query: 38  GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97
           G  +P+R  +L  P   GA       G+G     +    +  YR+LQN++YNVLERPRGW
Sbjct: 44  GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91

Query: 98  AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157
           AF+YH ++FLLVFSCLVLSV STI+E+++ +   L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 92  AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151

Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217
           CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211

Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277
           DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK  N  F +YAD+LWWG
Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271

Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337
            ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331

Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYD--------SILPSFRELALLFEHVQRA 389
           RR PAA LIQ+AWR Y+T++SR  L +TW YY+         ++P   +L LL     ++
Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPPLNQLELL--RNLKS 389

Query: 390 RNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRT 449
           ++G    L  R+ P P+ +PS+                     ++ +KDR+   S +   
Sbjct: 390 KSG----LAFRKDPPPEPSPSQ---------------------KVSLKDRV-FSSPRGVA 423

Query: 450 GPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLK---PRTSAEDA 506
              K      T+  SPS++Q  E  SP+KV KSWSF DR+R R + R+K    R ++E+A
Sbjct: 424 AKGKGSPQAQTVRRSPSADQSLE-DSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEA 482

Query: 507 --PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQ 564
             P E++ ++KS  CE   +D+ P +K  IR++ +++FLV+KRKFKE+LRPYDV DVIEQ
Sbjct: 483 SLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQ 542

Query: 565 YSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEK 624
           YSAGHLDML RIKSLQ+RVDQIVGRGP      +   KGP++AE+ ++ SMMGR+ KVEK
Sbjct: 543 YSAGHLDMLSRIKSLQSRVDQIVGRGPA--ITDKDRTKGPAEAELPEDPSMMGRLGKVEK 600

Query: 625 QVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVD-HEDISVSAQT 683
           QV S+E KLD L+  Y +  R G   +         +P+    YHSP D  E +      
Sbjct: 601 QVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCI 658

Query: 684 LSISRSVST 692
           + I RS S+
Sbjct: 659 VKIVRSSSS 667


>gi|26051262 potassium voltage-gated channel KQT-like protein 2
           isoform b [Homo sapiens]
          Length = 854

 Score =  668 bits (1723), Expect = 0.0
 Identities = 363/679 (53%), Positives = 462/679 (68%), Gaps = 69/679 (10%)

Query: 38  GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97
           G  +P+R  +L  P   GA       G+G     +    +  YR+LQN++YNVLERPRGW
Sbjct: 44  GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91

Query: 98  AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157
           AF+YH ++FLLVFSCLVLSV STI+E+++ +   L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 92  AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151

Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217
           CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211

Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277
           DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK  N  F +YAD+LWWG
Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271

Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337
            ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331

Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYD------------------SILPSFREL 379
           RR PAA LIQ+AWR Y+T++SR  L +TW YY+                   ++P   +L
Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQL 391

Query: 380 ALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDR 439
            LL     ++++G    L  R+ P P+ +PS+                     ++ +KDR
Sbjct: 392 ELL--RNLKSKSG----LAFRKDPPPEPSPSQ---------------------KVSLKDR 424

Query: 440 IRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLK- 498
           +   S +      K      T+  SPS++Q  E  SP+KV KSWSF DR+R R + R+K 
Sbjct: 425 V-FSSPRGVAAKGKGSPQAQTVRRSPSADQSLE-DSPSKVPKSWSFGDRSRARQAFRIKG 482

Query: 499 --PRTSAEDA--PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLR 554
              R ++E+A  P E++ ++KS  CE   +D+ P +K  IR++ +++FLV+KRKFKE+LR
Sbjct: 483 AASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLR 542

Query: 555 PYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEIS 614
           PYDV DVIEQYSAGHLDML RIKSLQ+RVDQIVGRGP      +   KGP++AE+ ++ S
Sbjct: 543 PYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPA--ITDKDRTKGPAEAELPEDPS 600

Query: 615 MMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVD- 673
           MMGR+ KVEKQV S+E KLD L+  Y +  R G   +         +P+    YHSP D 
Sbjct: 601 MMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAKEPEPAPPYHSPEDS 658

Query: 674 HEDISVSAQTLSISRSVST 692
            E +      + I RS S+
Sbjct: 659 REHVDRHGCIVKIVRSSSS 677


>gi|26051266 potassium voltage-gated channel KQT-like protein 2
           isoform d [Homo sapiens]
          Length = 841

 Score =  659 bits (1701), Expect = 0.0
 Identities = 359/678 (52%), Positives = 456/678 (67%), Gaps = 80/678 (11%)

Query: 38  GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97
           G  +P+R  +L  P   GA       G+G     +    +  YR+LQN++YNVLERPRGW
Sbjct: 44  GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91

Query: 98  AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157
           AF+YH ++FLLVFSCLVLSV STI+E+++ +   L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 92  AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151

Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217
           CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211

Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277
           DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK  N  F +YAD+LWWG
Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271

Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337
            ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331

Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYD------------------SILPSFREL 379
           RR PAA LIQ+AWR Y+T++SR  L +TW YY+                   ++P   +L
Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQL 391

Query: 380 ALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDR 439
            LL     ++++G    L  R+ P P+ +PS                             
Sbjct: 392 ELL--RNLKSKSG----LAFRKDPPPEPSPSP---------------------------- 417

Query: 440 IRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKP 499
            R  +++ +  P  Q     T+  SPS++Q  E  SP+KV KSWSF DR+R R + R+K 
Sbjct: 418 -RGVAAKGKGSPQAQ-----TVRRSPSADQSLE-DSPSKVPKSWSFGDRSRARQAFRIKG 470

Query: 500 RTSAEDA----PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRP 555
             S +++    P E++ ++KS  CE   +D+ P +K  IR++ +++FLV+KRKFKE+LRP
Sbjct: 471 AASRQNSEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRP 530

Query: 556 YDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISM 615
           YDV DVIEQYSAGHLDML RIKSLQ+RVDQIVGRGP      +   KGP++AE+ ++ SM
Sbjct: 531 YDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPA--ITDKDRTKGPAEAELPEDPSM 588

Query: 616 MGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVD-H 674
           MGR+ KVEKQV S+E KLD L+  Y +  R G   +         +P+    YHSP D  
Sbjct: 589 MGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAKEPEPAPPYHSPEDSR 646

Query: 675 EDISVSAQTLSISRSVST 692
           E +      + I RS S+
Sbjct: 647 EHVDRHGCIVKIVRSSSS 664


>gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo
           sapiens]
          Length = 872

 Score =  559 bits (1441), Expect = e-159
 Identities = 319/673 (47%), Positives = 419/673 (62%), Gaps = 109/673 (16%)

Query: 7   RRLGLGPPPGDAPRAELVALTAVQSEQG----EAGGGGSPRRLGLLGSPLPPGAPLPGPG 62
           R++GL P  GD  +  L AL A   + G    E GG    +R    G  L    PL  P 
Sbjct: 41  RKVGLAP--GDVEQVTL-ALGAGADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPV 97

Query: 63  SGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQ 122
                   +R++A   +YRR+Q  +Y+ LERPRGWA +YH  +FL+V  CL+L+VL+T +
Sbjct: 98  --------KRNNA---KYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFK 146

Query: 123 EHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVF 182
           E++ ++ + LL+LE   I +FG E+ +R+W+AGCCCRY+GW+GR +FARKP C++D  V 
Sbjct: 147 EYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVL 206

Query: 183 VASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAW 242
           +ASV V+A G QGN+ ATS LRS+RFLQILRM+RMDRRGGTWKLLGS + AHSKELITAW
Sbjct: 207 IASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAW 265

Query: 243 YIGFLVLIFASFLVYLAEKDA----------NSDFSSYADSLWWGTITLTTIGYGDKTPH 292
           YIGFL LI +SFLVYL EKD             +F +YAD+LWWG ITL TIGYGDKTP 
Sbjct: 266 YIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPK 325

Query: 293 TWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRL 352
           TW GR++AA F+L+G+SFFALPAGILGSG ALKVQEQHRQKHFEKRR PAA LIQAAWR 
Sbjct: 326 TWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRY 385

Query: 353 YSTDMSRAYLTATWYYYDSIL--PSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPS 410
           Y+T+ +R  L ATW +Y+S++  P FR+     E ++ A                     
Sbjct: 386 YATNPNRIDLVATWRFYESVVSFPFFRK-----EQLEAA--------------------- 419

Query: 411 RYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQV 470
                               S ++G+ DR+R+  S  R   +K  L  P      + + +
Sbjct: 420 -------------------SSQKLGLLDRVRL--SNPRGSNTKGKLFTPL-----NVDAI 453

Query: 471 GEATSPTKVQKSWSFNDRTRFRASLRLKPRT---SAEDA-PSEEVAEEKSYQCELTVDDI 526
            E  SP+K  K    N++ RFR + R+K      S+EDA   + +AE++ Y  +  ++D+
Sbjct: 454 EE--SPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDM 511

Query: 527 MPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQI 586
           +P +K  IR++RIL+F + K+KFKETLRPYDVKDVIEQYSAGHLDML RIK LQTR+D I
Sbjct: 512 IPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMI 571

Query: 587 VGRGPGDRKAREKGDKG-------------------PSDAEVVDEISMMGRVVKVEKQVQ 627
              GP      +K  KG                   PS +E+ D+ SMMG+ VKVE+QVQ
Sbjct: 572 FTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQ-SMMGKFVKVERQVQ 630

Query: 628 SIEHKLDLLLGFY 640
            +  KLD L+  +
Sbjct: 631 DMGKKLDFLVDMH 643


>gi|236462242 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 5 [Homo sapiens]
          Length = 822

 Score =  510 bits (1314), Expect = e-144
 Identities = 252/339 (74%), Positives = 281/339 (82%), Gaps = 24/339 (7%)

Query: 37  GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87
           GGGG  R         R+ LLG PL              S    +S   + +YRR+QN++
Sbjct: 70  GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115

Query: 88  YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147
           YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+
Sbjct: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175

Query: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207
           I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R
Sbjct: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235

Query: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267
           FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F
Sbjct: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295

Query: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327
           S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ
Sbjct: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355

Query: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATW 366
           EQHRQKHFEKRR PAANLIQ  WR Y+ D  ++   ATW
Sbjct: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATW 393



 Score =  182 bits (461), Expect = 1e-45
 Identities = 103/164 (62%), Positives = 126/164 (76%), Gaps = 8/164 (4%)

Query: 536 SIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGD 593
           S RI+KF VAKRKFKETLRPYDVKDVIEQYSAGHLDML RIKSLQTRVDQI+G+G    D
Sbjct: 414 SSRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSD 473

Query: 594 RKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--S 651
           +K+RE   K  ++ E  D++SM+GRVVKVEKQVQSIE KLD LL  Y + LR G+++  +
Sbjct: 474 KKSRE---KITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALA 530

Query: 652 LGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLS-ISRSVSTNM 694
           L + Q+P F+ + TSDY SPVD +D+S SAQ    +SRS S N+
Sbjct: 531 LASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANI 574


>gi|26051268 potassium voltage-gated channel KQT-like protein 2
           isoform e [Homo sapiens]
          Length = 393

 Score =  482 bits (1240), Expect = e-136
 Identities = 231/333 (69%), Positives = 273/333 (81%), Gaps = 12/333 (3%)

Query: 38  GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97
           G  +P+R  +L  P   GA       G+G     +    +  YR+LQN++YNVLERPRGW
Sbjct: 44  GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91

Query: 98  AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157
           AF+YH ++FLLVFSCLVLSV STI+E+++ +   L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 92  AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151

Query: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217
           CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211

Query: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277
           DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK  N  F +YAD+LWWG
Sbjct: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271

Query: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337
            ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331

Query: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYD 370
           RR PAA LIQ+AWR Y+T++SR  L +TW YY+
Sbjct: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYE 364


>gi|32479527 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 1 [Homo sapiens]
          Length = 676

 Score =  397 bits (1021), Expect = e-110
 Identities = 264/683 (38%), Positives = 362/683 (53%), Gaps = 125/683 (18%)

Query: 2   AEAPPR----RLGLGPPPG----DAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLP 53
           A +PPR    R G G  PG     A  A+    +   +E G AGG         L +P+ 
Sbjct: 4   ASSPPRAERKRWGWGRLPGARRGSAGLAKKCPFSLELAEGGPAGGA--------LYAPIA 55

Query: 54  PGAPLPGPGSGSGSACGQ----------------RSSAAHKRY-----RRLQNWVYNVLE 92
           PGAP P P +   +                    R S    R        +Q  VYN LE
Sbjct: 56  PGAPGPAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTHVQGRVYNFLE 115

Query: 93  RPRGW-AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRV 151
           RP GW  FVYH  +FL+V  CL+ SVLSTI+++  LA   L  +E V++V FG EY+VR+
Sbjct: 116 RPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRL 175

Query: 152 WSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQI 211
           WSAGC  +Y G  GR RFARKP  +ID IV VAS+ V+  G++G +FATSA+R +RFLQI
Sbjct: 176 WSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQI 235

Query: 212 LRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDA-----NSD 266
           LRM+ +DR+GGTW+LLGSVV+ H +ELIT  YIGFL LIF+S+ VYLAEKDA       +
Sbjct: 236 LRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVE 295

Query: 267 FSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKV 326
           F SYAD+LWWG +T+TTIGYGDK P TW+G+ +A+ F++  ISFFALPAGILGSGFALKV
Sbjct: 296 FGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKV 355

Query: 327 QEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHV 386
           Q++ RQKHF ++   AA+LIQ AWR Y+ +      ++TW  Y                 
Sbjct: 356 QQKQRQKHFNRQIPAAASLIQTAWRCYAAENPD---SSTWKIY----------------- 395

Query: 387 QRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQ 446
                       +R+AP               H   S S  P     + +K +       
Sbjct: 396 ------------IRKAP-------------RSHTLLSPS--PKPKKSVVVKKKKFKLDKD 428

Query: 447 RRTGPSKQHLAPPTMPTSPSSEQ-----------VGEATSPTKVQKSWSFNDRTR-FRAS 494
               P ++ L  P +   P  E+                SPT ++ S     RT  F   
Sbjct: 429 NGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAED 488

Query: 495 LRLKPRTSAEDAPSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLR 554
           L L+  T     P   +++ + +           A   VIR ++   + VAK+KF++  +
Sbjct: 489 LDLEGETLL--TPITHISQLREHH---------RATIKVIRRMQ---YFVAKKKFQQARK 534

Query: 555 PYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG-DKGPSDAEVVDEI 613
           PYDV+DVIEQYS GHL+++ RIK LQ R+DQ +G+        EK  D+G +        
Sbjct: 535 PYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSN-------- 586

Query: 614 SMMGRVVKVEKQVQSIEHKLDLL 636
           ++  R+ +VE +V  ++ +L L+
Sbjct: 587 TIGARLNRVEDKVTQLDQRLALI 609


>gi|32479525 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 2 [Homo sapiens]
          Length = 549

 Score =  363 bits (932), Expect = e-100
 Identities = 223/549 (40%), Positives = 311/549 (56%), Gaps = 87/549 (15%)

Query: 106 FLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQG 165
           FL+V  CL+ SVLSTI+++  LA   L  +E V++V FG EY+VR+WSAGC  +Y G  G
Sbjct: 3   FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62

Query: 166 RFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWK 225
           R RFARKP  +ID IV VAS+ V+  G++G +FATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 63  RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122

Query: 226 LLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDA-----NSDFSSYADSLWWGTIT 280
           LLGSVV+ H +ELIT  YIGFL LIF+S+ VYLAEKDA       +F SYAD+LWWG +T
Sbjct: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182

Query: 281 LTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRM 340
           +TTIGYGDK P TW+G+ +A+ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++  
Sbjct: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242

Query: 341 PAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVR 400
            AA+LIQ AWR Y+ +      ++TW  Y                             +R
Sbjct: 243 AAASLIQTAWRCYAAENPD---SSTWKIY-----------------------------IR 270

Query: 401 RAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPT 460
           +AP               H   S S  P     + +K +           P ++ L  P 
Sbjct: 271 KAP-------------RSHTLLSPS--PKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPH 315

Query: 461 MPTSPSSEQ-----------VGEATSPTKVQKSWSFNDRTR-FRASLRLKPRTSAEDAPS 508
           +   P  E+                SPT ++ S     RT  F   L L+  T     P 
Sbjct: 316 ITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLL--TPI 373

Query: 509 EEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAG 568
             +++ + +           A   VIR ++   + VAK+KF++  +PYDV+DVIEQYS G
Sbjct: 374 THISQLREHH---------RATIKVIRRMQ---YFVAKKKFQQARKPYDVRDVIEQYSQG 421

Query: 569 HLDMLGRIKSLQTRVDQIVGRGPGDRKAREKG-DKGPSDAEVVDEISMMGRVVKVEKQVQ 627
           HL+++ RIK LQ R+DQ +G+        EK  D+G +        ++  R+ +VE +V 
Sbjct: 422 HLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSN--------TIGARLNRVEDKVT 473

Query: 628 SIEHKLDLL 636
            ++ +L L+
Sbjct: 474 QLDQRLALI 482


>gi|27436974 potassium voltage-gated channel, Shab-related
           subfamily, member 2 [Homo sapiens]
          Length = 911

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 79/269 (29%), Positives = 136/269 (50%), Gaps = 26/269 (9%)

Query: 87  VYNVLERPRGWA---FVYHVFIFLLVFSCLVLSV--LSTIQEHQELA----NECLLILEF 137
           ++++LE+P        +  V I  +V S + LS+  L  +QE  E      N  L  +E 
Sbjct: 179 LWDLLEKPNSSVAAKILAIVSILFIVLSTIALSLNTLPELQETDEFGQLNDNRQLAHVEA 238

Query: 138 VMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVAS-VAVIAAGTQGN 196
           V I  F +EY++R  S+           +++F + P  VID +  +   V +    +  +
Sbjct: 239 VCIAWFTMEYLLRFLSS---------PNKWKFFKGPLNVIDLLAILPYYVTIFLTESNKS 289

Query: 197 IFATSALRSM----RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLIF 251
           +     +R +    R ++ILR++++ R     + LG  +     EL +   ++   ++IF
Sbjct: 290 VLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIF 349

Query: 252 ASFLVYLAEKDANSD-FSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISF 310
           +S LV+ AEKD ++  F+S   S WW TIT+TT+GYGD  P T LG+++     + G+  
Sbjct: 350 SS-LVFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLV 408

Query: 311 FALPAGILGSGFALKVQEQHRQKHFEKRR 339
            ALP  I+ + F+   +EQ RQ+   KRR
Sbjct: 409 IALPIPIIVNNFSEFYKEQKRQEKAIKRR 437


>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
           member 1 [Homo sapiens]
          Length = 858

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 78/270 (28%), Positives = 135/270 (50%), Gaps = 28/270 (10%)

Query: 87  VYNVLERPRGWA---FVYHVFIFLLVFSCLVLSVLSTIQEHQELA-------NECLLILE 136
           ++++LE+P        +  + I  +V S + LS L+T+ E Q L        N  L  +E
Sbjct: 175 LWDLLEKPNSSVAAKILAIISIMFIVLSTIALS-LNTLPELQSLDEFGQSTDNPQLAHVE 233

Query: 137 FVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVAS-VAVIAAGTQG 195
            V I  F +EY++R  S+           +++F + P   ID +  +   V +    +  
Sbjct: 234 AVCIAWFTMEYLLRFLSS---------PKKWKFFKGPLNAIDLLAILPYYVTIFLTESNK 284

Query: 196 NIFATSALRSM----RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLI 250
           ++     +R +    R ++ILR++++ R     + LG  +     EL +   ++   ++I
Sbjct: 285 SVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMI 344

Query: 251 FASFLVYLAEKDAN-SDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGIS 309
           F+S LV+ AEKD + + F S   S WW TIT+TT+GYGD  P T LG+++     + G+ 
Sbjct: 345 FSS-LVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVL 403

Query: 310 FFALPAGILGSGFALKVQEQHRQKHFEKRR 339
             ALP  I+ + F+   +EQ RQ+   KRR
Sbjct: 404 VIALPIPIIVNNFSEFYKEQKRQEKAIKRR 433


>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2a [Homo sapiens]
          Length = 613

 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 80/318 (25%), Positives = 141/318 (44%), Gaps = 63/318 (19%)

Query: 43  RRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERP---RGWAF 99
           +RLG+        A L GP   SG            R+RRLQ  ++ + E P   R   F
Sbjct: 188 KRLGI-----EDAAGLGGPDGKSG------------RWRRLQPRMWALFEDPYSSRAARF 230

Query: 100 VYHVFIFLLVFS----CL---------------VLSVLSTIQEHQELANECLLILEFVMI 140
           +    +F ++ S    CL               V++  S + +++   +  L  +E V +
Sbjct: 231 IAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCV 290

Query: 141 VVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV---FVASVAVIAAGTQGNI 197
           V F  E++VR+  +           +  F +    +IDF+    F   V +    ++   
Sbjct: 291 VWFTFEFLVRIVFS---------PNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAK 341

Query: 198 FATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIGFLVLIFASFLV 256
                LR +RF++ILR+ ++ R     ++LG  + A + E L+   ++   VLIFA+ ++
Sbjct: 342 DVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFAT-MI 400

Query: 257 YLAEK----------DANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALL 306
           Y AE+            ++ F +     WW  +T+TT+GYGD  P TW G ++ A  AL 
Sbjct: 401 YYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALA 460

Query: 307 GISFFALPAGILGSGFAL 324
           G+   A+P  ++ + F +
Sbjct: 461 GVLTIAMPVPVIVNNFGM 478


>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2b [Homo sapiens]
          Length = 638

 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 80/318 (25%), Positives = 141/318 (44%), Gaps = 63/318 (19%)

Query: 43  RRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERP---RGWAF 99
           +RLG+        A L GP   SG            R+RRLQ  ++ + E P   R   F
Sbjct: 188 KRLGI-----EDAAGLGGPDGKSG------------RWRRLQPRMWALFEDPYSSRAARF 230

Query: 100 VYHVFIFLLVFS----CL---------------VLSVLSTIQEHQELANECLLILEFVMI 140
           +    +F ++ S    CL               V++  S + +++   +  L  +E V +
Sbjct: 231 IAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCV 290

Query: 141 VVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV---FVASVAVIAAGTQGNI 197
           V F  E++VR+  +           +  F +    +IDF+    F   V +    ++   
Sbjct: 291 VWFTFEFLVRIVFS---------PNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAK 341

Query: 198 FATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIGFLVLIFASFLV 256
                LR +RF++ILR+ ++ R     ++LG  + A + E L+   ++   VLIFA+ ++
Sbjct: 342 DVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFAT-MI 400

Query: 257 YLAEK----------DANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALL 306
           Y AE+            ++ F +     WW  +T+TT+GYGD  P TW G ++ A  AL 
Sbjct: 401 YYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALA 460

Query: 307 GISFFALPAGILGSGFAL 324
           G+   A+P  ++ + F +
Sbjct: 461 GVLTIAMPVPVIVNNFGM 478


>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2c [Homo sapiens]
          Length = 558

 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 80/318 (25%), Positives = 141/318 (44%), Gaps = 63/318 (19%)

Query: 43  RRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERP---RGWAF 99
           +RLG+        A L GP   SG            R+RRLQ  ++ + E P   R   F
Sbjct: 188 KRLGI-----EDAAGLGGPDGKSG------------RWRRLQPRMWALFEDPYSSRAARF 230

Query: 100 VYHVFIFLLVFS----CL---------------VLSVLSTIQEHQELANECLLILEFVMI 140
           +    +F ++ S    CL               V++  S + +++   +  L  +E V +
Sbjct: 231 IAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCV 290

Query: 141 VVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV---FVASVAVIAAGTQGNI 197
           V F  E++VR+  +           +  F +    +IDF+    F   V +    ++   
Sbjct: 291 VWFTFEFLVRIVFS---------PNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAK 341

Query: 198 FATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIGFLVLIFASFLV 256
                LR +RF++ILR+ ++ R     ++LG  + A + E L+   ++   VLIFA+ ++
Sbjct: 342 DVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFAT-MI 400

Query: 257 YLAEK----------DANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALL 306
           Y AE+            ++ F +     WW  +T+TT+GYGD  P TW G ++ A  AL 
Sbjct: 401 YYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALA 460

Query: 307 GISFFALPAGILGSGFAL 324
           G+   A+P  ++ + F +
Sbjct: 461 GVLTIAMPVPVIVNNFGM 478


>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
           isoform c [Homo sapiens]
          Length = 626

 Score = 90.5 bits (223), Expect = 5e-18
 Identities = 86/351 (24%), Positives = 155/351 (44%), Gaps = 51/351 (14%)

Query: 25  ALTAVQSEQGEAGGGGSPRRLG-----LLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKR 79
           AL   +S  G   G G     G     L    L P     G G+GSG   G +     + 
Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQP----RM 212

Query: 80  YRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCL--------------VLSV--LSTIQE 123
           +   ++   +   R   +A ++ + + +  F CL              +L V  ++++  
Sbjct: 213 WALFEDPYSSRAARVVAFASLFFILVSITTF-CLETHEAFNIDRNVTEILRVGNITSVHF 271

Query: 124 HQELANECLLI-LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV- 181
            +E+  E +L  +E V ++ F LE++VR+     CC          F +    +IDF+  
Sbjct: 272 RREVETEPILTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAI 322

Query: 182 --FVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-L 238
             F   V +    ++        LR +RF++ILR+ ++ R     ++LG  + A + E L
Sbjct: 323 LPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFL 382

Query: 239 ITAWYIGFLVLIFASFLVYLAEK----------DANSDFSSYADSLWWGTITLTTIGYGD 288
           +   ++   VLIFA+ ++Y AE+          + ++DF +     WW  +T+TT+GYGD
Sbjct: 383 LLIIFLALGVLIFAT-MIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGD 441

Query: 289 KTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRR 339
             P TW G ++ A  AL G+   A+P  ++ + F +       ++   K+R
Sbjct: 442 MYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
           isoform a [Homo sapiens]
          Length = 635

 Score = 90.5 bits (223), Expect = 5e-18
 Identities = 86/351 (24%), Positives = 155/351 (44%), Gaps = 51/351 (14%)

Query: 25  ALTAVQSEQGEAGGGGSPRRLG-----LLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKR 79
           AL   +S  G   G G     G     L    L P     G G+GSG   G +     + 
Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQP----RM 212

Query: 80  YRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCL--------------VLSV--LSTIQE 123
           +   ++   +   R   +A ++ + + +  F CL              +L V  ++++  
Sbjct: 213 WALFEDPYSSRAARVVAFASLFFILVSITTF-CLETHEAFNIDRNVTEILRVGNITSVHF 271

Query: 124 HQELANECLLI-LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV- 181
            +E+  E +L  +E V ++ F LE++VR+     CC          F +    +IDF+  
Sbjct: 272 RREVETEPILTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAI 322

Query: 182 --FVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-L 238
             F   V +    ++        LR +RF++ILR+ ++ R     ++LG  + A + E L
Sbjct: 323 LPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFL 382

Query: 239 ITAWYIGFLVLIFASFLVYLAEK----------DANSDFSSYADSLWWGTITLTTIGYGD 288
           +   ++   VLIFA+ ++Y AE+          + ++DF +     WW  +T+TT+GYGD
Sbjct: 383 LLIIFLALGVLIFAT-MIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGD 441

Query: 289 KTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRR 339
             P TW G ++ A  AL G+   A+P  ++ + F +       ++   K+R
Sbjct: 442 MYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
           isoform b [Homo sapiens]
          Length = 582

 Score = 90.5 bits (223), Expect = 5e-18
 Identities = 86/351 (24%), Positives = 155/351 (44%), Gaps = 51/351 (14%)

Query: 25  ALTAVQSEQGEAGGGGSPRRLG-----LLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKR 79
           AL   +S  G   G G     G     L    L P     G G+GSG   G +     + 
Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQP----RM 212

Query: 80  YRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCL--------------VLSV--LSTIQE 123
           +   ++   +   R   +A ++ + + +  F CL              +L V  ++++  
Sbjct: 213 WALFEDPYSSRAARVVAFASLFFILVSITTF-CLETHEAFNIDRNVTEILRVGNITSVHF 271

Query: 124 HQELANECLLI-LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV- 181
            +E+  E +L  +E V ++ F LE++VR+     CC          F +    +IDF+  
Sbjct: 272 RREVETEPILTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAI 322

Query: 182 --FVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-L 238
             F   V +    ++        LR +RF++ILR+ ++ R     ++LG  + A + E L
Sbjct: 323 LPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFL 382

Query: 239 ITAWYIGFLVLIFASFLVYLAEK----------DANSDFSSYADSLWWGTITLTTIGYGD 288
           +   ++   VLIFA+ ++Y AE+          + ++DF +     WW  +T+TT+GYGD
Sbjct: 383 LLIIFLALGVLIFAT-MIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGD 441

Query: 289 KTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRR 339
             P TW G ++ A  AL G+   A+P  ++ + F +       ++   K+R
Sbjct: 442 MYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|6912444 potassium voltage-gated channel, subfamily G, member 2
           [Homo sapiens]
          Length = 466

 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 99/345 (28%), Positives = 144/345 (41%), Gaps = 46/345 (13%)

Query: 17  DAPRAELVALTAVQSEQGEAGGG-GSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSA 75
           D  R E   L  ++  + EA      P   G  GSP                A G R   
Sbjct: 111 DEARLERCCLRRLRRREEEAAEARAGPTERGAQGSP--------------ARALGPRGRL 156

Query: 76  AHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSC-LVLSVLSTIQEHQELANEC--- 131
              R RRL++ V N      G  F      F+ V +  L LS +  I+  +E   EC   
Sbjct: 157 QRGR-RRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEE-RGECSPK 214

Query: 132 ---LLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV----FVA 184
              L +LE V +  F  E+++R   A   C          F R P  +ID +     +V+
Sbjct: 215 CRSLFVLETVCVAWFSFEFLLRSLQAESKCA---------FLRAPLNIIDILALLPFYVS 265

Query: 185 SVAVIAAGTQGNIFATSA---LRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITA 241
            +  +AAG  G      A   LR +R L++L ++R+ R     + LG  +   ++E    
Sbjct: 266 LLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREF--G 323

Query: 242 WYIGFLVLIFASF--LVYLAEKD--ANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGR 297
             + FL +  A F  LV+LAE++  A  DFSS   S WW  I++TT+GYGD  P +  G+
Sbjct: 324 LLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQ 383

Query: 298 VLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPA 342
           V+A    L GI   A P   +   F+    E   Q+       PA
Sbjct: 384 VVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPA 428


>gi|27436984 potassium voltage-gated channel, Shal-related
           subfamily, member 3 isoform 1 [Homo sapiens]
          Length = 655

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 59/229 (25%), Positives = 112/229 (48%), Gaps = 16/229 (6%)

Query: 135 LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQ 194
           L+   +++F +EY++R+++A           R+RF R    +ID +  +     I     
Sbjct: 229 LDTACVMIFTVEYLLRLFAA---------PSRYRFIRSVMSIIDVVAIMPYY--IGLVMT 277

Query: 195 GNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLIFAS 253
            N   + A  ++R  ++ R+ +  R     ++LG  + + + EL    + +   ++IFA+
Sbjct: 278 NNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFAT 337

Query: 254 FLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFAL 313
            + Y  +  + S F+S   S W+  +T+TT+GYGD  P T  G++  +  +L G+   AL
Sbjct: 338 VMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIAL 397

Query: 314 PAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYL 362
           P  ++ S F+   +  H+ +  +KRR      + A  R+  T  S AYL
Sbjct: 398 PVPVIVSNFS---RIYHQNQRADKRRAQKKARL-ARIRVAKTGSSNAYL 442


>gi|27436986 potassium voltage-gated channel, Shal-related
           subfamily, member 3 isoform 2 [Homo sapiens]
          Length = 636

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 59/229 (25%), Positives = 112/229 (48%), Gaps = 16/229 (6%)

Query: 135 LEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQ 194
           L+   +++F +EY++R+++A           R+RF R    +ID +  +     I     
Sbjct: 229 LDTACVMIFTVEYLLRLFAA---------PSRYRFIRSVMSIIDVVAIMPYY--IGLVMT 277

Query: 195 GNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLIFAS 253
            N   + A  ++R  ++ R+ +  R     ++LG  + + + EL    + +   ++IFA+
Sbjct: 278 NNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFAT 337

Query: 254 FLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFAL 313
            + Y  +  + S F+S   S W+  +T+TT+GYGD  P T  G++  +  +L G+   AL
Sbjct: 338 VMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIAL 397

Query: 314 PAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYL 362
           P  ++ S F+   +  H+ +  +KRR      + A  R+  T  S AYL
Sbjct: 398 PVPVIVSNFS---RIYHQNQRADKRRAQKKARL-ARIRVAKTGSSNAYL 442


>gi|88758565 potassium voltage-gated channel, shaker-related
           subfamily, member 3 [Homo sapiens]
          Length = 575

 Score = 87.4 bits (215), Expect = 4e-17
 Identities = 56/196 (28%), Positives = 97/196 (49%), Gaps = 16/196 (8%)

Query: 134 ILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIA--- 190
           ++E + I+ F  E +VR ++            +  F+R    +ID +  +     +    
Sbjct: 297 VVETLCIIWFSFELLVRFFAC---------PSKATFSRNIMNLIDIVAIIPYFITLGTEL 347

Query: 191 AGTQGN---IFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFL 247
           A  QGN     + + LR +R +++ R+ ++ R     ++LG  + A  +EL    +  F+
Sbjct: 348 AERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFI 407

Query: 248 VLIFASFLVYLAEKD-ANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALL 306
            +I  S  VY AE D   S FSS  D+ WW  +T+TT+GYGD  P T  G+++ +  A+ 
Sbjct: 408 GVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIA 467

Query: 307 GISFFALPAGILGSGF 322
           G+   ALP  ++ S F
Sbjct: 468 GVLTIALPVPVIVSNF 483


>gi|119395748 potassium voltage-gated channel subfamily A member 1
           [Homo sapiens]
          Length = 495

 Score = 86.7 bits (213), Expect = 7e-17
 Identities = 57/207 (27%), Positives = 105/207 (50%), Gaps = 6/207 (2%)

Query: 119 STIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVID 178
           +T+  +  +  +   I+E + I+ F  E +VR ++  C  +   ++    F      +I 
Sbjct: 208 TTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFA--CPSKTDFFKNIMNFI-DIVAIIP 264

Query: 179 FIVFVASVAVIAAGTQGNIFATSA--LRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSK 236
           + + + +      G Q    ATS   LR +R +++ R+ ++ R     ++LG  + A  +
Sbjct: 265 YFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMR 324

Query: 237 ELITAWYIGFLVLIFASFLVYLAE-KDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWL 295
           EL    +  F+ +I  S  VY AE ++A S FSS  D+ WW  +++TT+GYGD  P T  
Sbjct: 325 ELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIG 384

Query: 296 GRVLAAGFALLGISFFALPAGILGSGF 322
           G+++ +  A+ G+   ALP  ++ S F
Sbjct: 385 GKIVGSLCAIAGVLTIALPVPVIVSNF 411


>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
           [Homo sapiens]
          Length = 494

 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 73/255 (28%), Positives = 117/255 (45%), Gaps = 24/255 (9%)

Query: 75  AAHKRYRRLQNWVYNVLERPRGW--AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANE-- 130
           AA  R+RR Q  V+  LE+P     A V  V  FLL+    V+  + TI E Q L  E  
Sbjct: 156 AAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQVLDAEGN 215

Query: 131 -----CLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIV---F 182
                 L  +E   I  F LEY++R++S+           +  FA     ++D +    F
Sbjct: 216 RVEHPTLENVETACIGWFTLEYLLRLFSS---------PNKLHFALSFMNIVDVLAILPF 266

Query: 183 VASVAVIAAGTQGNIFAT--SALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-I 239
             S+ +   G +         A++++R ++I R+ ++ R     + L   +    KEL +
Sbjct: 267 YVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGL 326

Query: 240 TAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVL 299
              Y+   + +F++    + +    + F S   S WW  IT+TT+GYGD  P T LG++ 
Sbjct: 327 LLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLN 386

Query: 300 AAGFALLGISFFALP 314
           AA   L G+   ALP
Sbjct: 387 AAISFLCGVIAIALP 401


>gi|4504817 potassium voltage-gated channel, shaker-related
           subfamily, member 4 [Homo sapiens]
          Length = 653

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 59/233 (25%), Positives = 105/233 (45%), Gaps = 23/233 (9%)

Query: 129 NECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAV 188
           N+   I+E V IV F  E++VR ++            +  F +    +ID +  +     
Sbjct: 368 NDPFFIVETVCIVWFSFEFVVRCFAC---------PSQALFFKNIMNIIDIVSILPYFIT 418

Query: 189 IAA----------GTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL 238
           +            G Q    + + LR +R +++ R+ ++ R     ++LG  + A  +EL
Sbjct: 419 LGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMREL 478

Query: 239 ITAWYIGFLVLIFASFLVYLAEKDA-NSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGR 297
               +  F+ +I  S  VY AE D   + F S  D+ WW  +T+TT+GYGD  P T  G+
Sbjct: 479 GLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGK 538

Query: 298 VLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAW 350
           ++ +  A+ G+   ALP  ++ S F       HR+   E++     N +   +
Sbjct: 539 IVGSLCAIAGVLTIALPVPVIVSNFN---YFYHRETENEEQTQLTQNAVSCPY 588


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,444,531
Number of Sequences: 37866
Number of extensions: 1461805
Number of successful extensions: 11786
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 210
Number of HSP's that attempted gapping in prelim test: 7933
Number of HSP's gapped (non-prelim): 3699
length of query: 695
length of database: 18,247,518
effective HSP length: 109
effective length of query: 586
effective length of database: 14,120,124
effective search space: 8274392664
effective search space used: 8274392664
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.