Guide to the Human Genome
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Search of human proteins with 25777645

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|25777645 small conductance calcium-activated potassium
channel protein 2 isoform a [Homo sapiens]
         (579 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|25777645 small conductance calcium-activated potassium channe...  1142   0.0  
gi|116805330 small conductance calcium-activated potassium chann...   816   0.0  
gi|25777643 potassium intermediate/small conductance calcium-act...   714   0.0  
gi|25777650 small conductance calcium-activated potassium channe...   669   0.0  
gi|25777647 small conductance calcium-activated potassium channe...   454   e-127
gi|4504859 intermediate conductance calcium-activated potassium ...   335   5e-92
gi|236462242 potassium voltage-gated channel, KQT-like subfamily...    59   1e-08
gi|236462079 potassium voltage-gated channel, KQT-like subfamily...    55   2e-07
gi|28373065 potassium voltage-gated channel, KQT-like subfamily,...    55   2e-07
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]     53   7e-07
gi|122937319 even-skipped homeobox 2 [Homo sapiens]                    53   9e-07
gi|236461942 potassium voltage-gated channel, KQT-like subfamily...    51   3e-06
gi|236461719 potassium voltage-gated channel, KQT-like subfamily...    51   3e-06
gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens]          51   3e-06
gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens]          51   3e-06
gi|126090909 engrailed homeobox 1 [Homo sapiens]                       50   4e-06
gi|13994236 cat eye syndrome chromosome region, candidate 6 isof...    49   1e-05
gi|22748877 basic helix-loop-helix domain containing, class B, 5...    47   4e-05
gi|238859557 regulatory factor X1 [Homo sapiens]                       47   5e-05
gi|21322252 androgen receptor isoform 1 [Homo sapiens]                 47   5e-05
gi|26638655 potassium voltage-gated channel KQT-like protein 4 i...    47   5e-05
gi|26638653 potassium voltage-gated channel KQT-like protein 4 i...    47   5e-05
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]               46   8e-05
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]               46   8e-05
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]               46   8e-05
gi|26051268 potassium voltage-gated channel KQT-like protein 2 i...    45   1e-04
gi|26051260 potassium voltage-gated channel KQT-like protein 2 i...    45   1e-04
gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]      45   1e-04
gi|9789987 potassium voltage-gated channel, Shal-related subfami...    45   2e-04
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H...    45   2e-04

>gi|25777645 small conductance calcium-activated potassium channel
           protein 2 isoform a [Homo sapiens]
          Length = 579

 Score = 1142 bits (2954), Expect = 0.0
 Identities = 579/579 (100%), Positives = 579/579 (100%)

Query: 1   MSSCRYNGGVMRPLSNLSASRRNLHEMDSEAQPLQPPASVGGGGGASSPSAAAAAAAAVS 60
           MSSCRYNGGVMRPLSNLSASRRNLHEMDSEAQPLQPPASVGGGGGASSPSAAAAAAAAVS
Sbjct: 1   MSSCRYNGGVMRPLSNLSASRRNLHEMDSEAQPLQPPASVGGGGGASSPSAAAAAAAAVS 60

Query: 61  SSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHGSSSGTKSSKKKNQNIGYK 120
           SSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHGSSSGTKSSKKKNQNIGYK
Sbjct: 61  SSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHGSSSGTKSSKKKNQNIGYK 120

Query: 121 LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTII 180
           LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTII
Sbjct: 121 LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTII 180

Query: 181 LLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTAR 240
           LLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTAR
Sbjct: 181 LLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTAR 240

Query: 241 LAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRF 300
           LAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRF
Sbjct: 241 LAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRF 300

Query: 301 VMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIG 360
           VMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIG
Sbjct: 301 VMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIG 360

Query: 361 YGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVK 420
           YGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVK
Sbjct: 361 YGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVK 420

Query: 421 NAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLV 480
           NAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLV
Sbjct: 421 NAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLV 480

Query: 481 DLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFI 540
           DLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFI
Sbjct: 481 DLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFI 540

Query: 541 EAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS 579
           EAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS
Sbjct: 541 EAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS 579


>gi|116805330 small conductance calcium-activated potassium channel
           protein 3 isoform a [Homo sapiens]
          Length = 731

 Score =  816 bits (2108), Expect = 0.0
 Identities = 427/579 (73%), Positives = 476/579 (82%), Gaps = 25/579 (4%)

Query: 1   MSSCRYNGGVMRPLSNLSASRRNLHEMDSEAQPLQPPASVGGGGGASSPSAAAAAAAAVS 60
           MSSC+Y+GGVM+PLS LSASRRNL E ++E QPLQ            SPS          
Sbjct: 175 MSSCKYSGGVMKPLSRLSASRRNLIEAETEGQPLQ----------LFSPS---------- 214

Query: 61  SSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHGSSSGTKSSKKKNQNIGYK 120
            + PEIV+S  E N+++   L+      +    G    +   S++  K++K+KNQNIGYK
Sbjct: 215 -NPPEIVISSREDNHAHQTLLHHPNATHNHQHAG----TTASSTTFPKANKRKNQNIGYK 269

Query: 121 LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTII 180
           LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWG Y K S++SLALKCLISLSTII
Sbjct: 270 LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTII 329

Query: 181 LLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTAR 240
           LLGLII YH RE+QLF++DNGADDWRIAMTYERI +I LE+LVCAIHPIPG Y F WTAR
Sbjct: 330 LLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTAR 389

Query: 241 LAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRF 300
           LAFSY PS   ADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRF
Sbjct: 390 LAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRF 449

Query: 301 VMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIG 360
           VMKTLMTICPGTVLLVFSISLWIIAAWTVR CERYHDQQDVTSNFLGAMWLISITFLSIG
Sbjct: 450 VMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIG 509

Query: 361 YGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVK 420
           YGDMVP+TYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKR+K
Sbjct: 510 YGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIK 569

Query: 421 NAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLV 480
           NAAANVLRETWLIYK+TKL+KKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKL+DQANTLV
Sbjct: 570 NAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLV 629

Query: 481 DLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFI 540
           DL+K QN+MYD+I++LN+RSED EK+I +LE+KLE L  S ++LP LI+ T+RQQQ+  +
Sbjct: 630 DLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLL 689

Query: 541 EAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS 579
            A +E+    V      +  S      SST+ PT   SS
Sbjct: 690 SAIIEARGVSVAVGTTHTPISDSPIGVSSTSFPTPYTSS 728


>gi|25777643 potassium intermediate/small conductance
           calcium-activated channel, subfamily N, member 1 [Homo
           sapiens]
          Length = 543

 Score =  714 bits (1844), Expect = 0.0
 Identities = 372/536 (69%), Positives = 419/536 (78%), Gaps = 31/536 (5%)

Query: 1   MSSCRYNGGVMRPLSNLSASRRNLHEMDSEAQPLQPPASVGGGGGASSPSAAAAAAAAVS 60
           M+S  YNG V RPL +   +            P QPP S G          A +  A  S
Sbjct: 1   MNSHSYNGSVGRPLGSGPGALGRDPPDPEAGHPPQPPHSPG-----LQVVVAKSEPARPS 55

Query: 61  SSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHGSSSGTKSSKKKNQNIGYK 120
             +P     +P+  + +                           +G + +  K  N+G++
Sbjct: 56  PGSPR---GQPQDQDDDE--------------------DDEEDEAGRQRASGKPSNVGHR 92

Query: 121 LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTII 180
           LGHRRALFEKRKRLSDYALIFGMFGIVVMV ETELSWG Y K SLYS ALKCLISLST I
Sbjct: 93  LGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESLYSFALKCLISLSTAI 152

Query: 181 LLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTAR 240
           LLGL+++YHAREIQLFMVDNGADDWRIAMT ER+F I LE+ VCAIHP+PG+Y FTWTAR
Sbjct: 153 LLGLVVLYHAREIQLFMVDNGADDWRIAMTCERVFLISLELAVCAIHPVPGHYRFTWTAR 212

Query: 241 LAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRF 300
           LAF+YAPS   ADVD++LSIPMFLRLYL+ RVMLLHSK+FTDASSRSIGALNKI FNTRF
Sbjct: 213 LAFTYAPSVAEADVDVLLSIPMFLRLYLLGRVMLLHSKIFTDASSRSIGALNKITFNTRF 272

Query: 301 VMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIG 360
           VMKTLMTICPGTVLLVFSIS WIIAAWTVR CERYHD+Q+VTSNFLGAMWLISITFLSIG
Sbjct: 273 VMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIG 332

Query: 361 YGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVK 420
           YGDMVP+TYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVK
Sbjct: 333 YGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVK 392

Query: 421 NAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQ---LRSVKMEQRKLNDQAN 477
           NAAANVLRETWLIYK+T+LVKK D A+VRKHQRKFLQAIHQ   LRSVK+EQ KLNDQAN
Sbjct: 393 NAAANVLRETWLIYKHTRLVKKPDQARVRKHQRKFLQAIHQAQKLRSVKIEQGKLNDQAN 452

Query: 478 TLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIR 533
           TL DLAKTQ +MYD++S+L+ + E+ E R+ TLE++L+ L  S+ ALPGLI+Q IR
Sbjct: 453 TLTDLAKTQTVMYDLVSELHAQHEELEARLATLESRLDALGASLQALPGLIAQAIR 508


>gi|25777650 small conductance calcium-activated potassium channel
           protein 3 isoform b [Homo sapiens]
          Length = 426

 Score =  669 bits (1725), Expect = 0.0
 Identities = 339/418 (81%), Positives = 370/418 (88%)

Query: 162 KASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEI 221
           K S++SLALKCLISLSTIILLGLII YH RE+QLF++DNGADDWRIAMTYERI +I LE+
Sbjct: 6   KDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEM 65

Query: 222 LVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFT 281
           LVCAIHPIPG Y F WTARLAFSY PS   ADVDIILSIPMFLRLYLIARVMLLHSKLFT
Sbjct: 66  LVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFT 125

Query: 282 DASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDV 341
           DASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVR CERYHDQQDV
Sbjct: 126 DASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDV 185

Query: 342 TSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTK 401
           TSNFLGAMWLISITFLSIGYGDMVP+TYCGKGVCLLTGIMGAGCTALVVAVVARKLELTK
Sbjct: 186 TSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTK 245

Query: 402 AEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQ 461
           AEKHVHNFMMDTQLTKR+KNAAANVLRETWLIYK+TKL+KKIDHAKVRKHQRKFLQAIHQ
Sbjct: 246 AEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQ 305

Query: 462 LRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSI 521
           LRSVKMEQRKL+DQANTLVDL+K QN+MYD+I++LN+RSED EK+I +LE+KLE L  S 
Sbjct: 306 LRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASF 365

Query: 522 HALPGLISQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS 579
           ++LP LI+ T+RQQQ+  + A +E+    V      +  S      SST+ PT   SS
Sbjct: 366 NSLPLLIADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSSTSFPTPYTSS 423


>gi|25777647 small conductance calcium-activated potassium channel
           protein 2 isoform b [Homo sapiens]
          Length = 231

 Score =  454 bits (1167), Expect = e-127
 Identities = 231/231 (100%), Positives = 231/231 (100%)

Query: 349 MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 408
           MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN
Sbjct: 1   MWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHN 60

Query: 409 FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME 468
           FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME
Sbjct: 61  FMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKME 120

Query: 469 QRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLI 528
           QRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLI
Sbjct: 121 QRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLI 180

Query: 529 SQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS 579
           SQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS
Sbjct: 181 SQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS 231


>gi|4504859 intermediate conductance calcium-activated potassium
           channel protein 1 [Homo sapiens]
          Length = 427

 Score =  335 bits (860), Expect = 5e-92
 Identities = 183/400 (45%), Positives = 249/400 (62%), Gaps = 8/400 (2%)

Query: 121 LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTII 180
           L  R+ L E+ K L+ +AL+    GI +MV+  E+ W      +LY   +KC IS+ST +
Sbjct: 12  LRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFLVKCTISISTFL 71

Query: 181 LLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGN---YTFTW 237
           LL LI+ +HA+E+QLFM DNG  DWR+A+T  +   I LE++VC +HP P          
Sbjct: 72  LLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPAPVRGPPCVQDL 131

Query: 238 TARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFN 297
            A L             + +LS+ M LRLYL+ R +LL S +  +AS RSIGALN++ F 
Sbjct: 132 GAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYRSIGALNQVRFR 191

Query: 298 TRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFL 357
             FV K  M   PG +LL  ++ LW+  AW +   ER     + T +    +WLI ITFL
Sbjct: 192 HWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAER--QAVNATGHLSDTLWLIPITFL 249

Query: 358 SIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTK 417
           +IGYGD+VP T  GK VCL TG+MG  CTAL+VAVVARKLE  KAEKHVHNFMMD Q TK
Sbjct: 250 TIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTK 309

Query: 418 RVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQAN 477
            +K +AA VL+E W+ YK+T+  +K  HA  R+HQRK L AI+  R V+++ RKL +Q N
Sbjct: 310 EMKESAARVLQEAWMFYKHTR--RKESHA-ARRHQRKLLAAINAFRQVRLKHRKLREQVN 366

Query: 478 TLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETL 517
           ++VD++K   I+YD+  +L+      EK+I TL  KL+ L
Sbjct: 367 SMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDAL 406


>gi|236462242 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 5 [Homo sapiens]
          Length = 822

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 122/538 (22%), Positives = 205/538 (38%), Gaps = 90/538 (16%)

Query: 41  GGGGGASSPSAAAAAAAA----------VSSSAPEIVVSKPEHNNSNNLALYGTGGGGST 90
           GG  G    S AAAAAA           V S    ++++       + L L GT      
Sbjct: 11  GGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARG-DGLLLLGTRAATLG 69

Query: 91  GGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMV 150
           GGGGG   S  G      S   K  +       RR +  K +R+ +Y         +  V
Sbjct: 70  GGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNV--KYRRVQNY---------LYNV 118

Query: 151 IETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMT 210
           +E    W     A ++ L   CLI     + +   I  H +          A    + + 
Sbjct: 119 LERPRGWAFIYHAFVFLLVFGCLI-----LSVFSTIPEHTKL---------ASSCLLILE 164

Query: 211 YERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIA 270
           +  I    LE ++             W  RL F+  P      +D I+         LIA
Sbjct: 165 FVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCV---IDTIV---------LIA 212

Query: 271 RVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSI----SLWIIAA 326
            + ++ +K  T  +  +  AL  + F  + +    M    GT  L+ S+    S  +I A
Sbjct: 213 SIAVVSAK--TQGNIFATSALRSLRF-LQILRMVRMDRRGGTWKLLGSVVYAHSKELITA 269

Query: 327 WTV-------RACERYHDQQDVT---SNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCL 376
           W +        +   Y  ++D     S +  A+W  +IT  +IGYGD  P T+ G+ +  
Sbjct: 270 WYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSA 329

Query: 377 LTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKN 436
              ++G    AL   ++     L   E+H           ++ +N AAN+++  W  Y  
Sbjct: 330 GFALLGISFFALPAGILGSGFALKVQEQHRQKHF------EKRRNPAANLIQCVWRSYAA 383

Query: 437 TKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTL-VDLAKTQNIM-----Y 490
            +  K +  A  + H    L+A+H     K EQ + + +     V   K +  +      
Sbjct: 384 DE--KSVSIATWKPH----LKALHTCSPTKKEQGEASSRIMKFHVAKRKFKETLRPYDVK 437

Query: 491 DMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFIEAQMESYD 548
           D+I   +    D   RI +L+T+++ ++G      G I  T  ++ R+ I A+ E+ D
Sbjct: 438 DVIEQYSAGHLDMLCRIKSLQTRVDQILGK-----GQI--TSDKKSREKITAEHETTD 488


>gi|236462079 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 4 [Homo sapiens]
          Length = 951

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 104/453 (22%), Positives = 168/453 (37%), Gaps = 77/453 (16%)

Query: 41  GGGGGASSPSAAAAAAAA----------VSSSAPEIVVSKPEHNNSNNLALYGTGGGGST 90
           GG  G    S AAAAAA           V S    ++++       + L L GT      
Sbjct: 11  GGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARG-DGLLLLGTRAATLG 69

Query: 91  GGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMV 150
           GGGGG   S  G      S   K  +       RR +  K +R+ +Y         +  V
Sbjct: 70  GGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNV--KYRRVQNY---------LYNV 118

Query: 151 IETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMT 210
           +E    W     A ++ L   CLI     + +   I  H +          A    + + 
Sbjct: 119 LERPRGWAFIYHAFVFLLVFGCLI-----LSVFSTIPEHTKL---------ASSCLLILE 164

Query: 211 YERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIA 270
           +  I    LE ++             W  RL F+  P      +D I+         LIA
Sbjct: 165 FVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCV---IDTIV---------LIA 212

Query: 271 RVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSI----SLWIIAA 326
            + ++ +K  T  +  +  AL  + F  + +    M    GT  L+ S+    S  +I A
Sbjct: 213 SIAVVSAK--TQGNIFATSALRSLRF-LQILRMVRMDRRGGTWKLLGSVVYAHSKELITA 269

Query: 327 WTV-------RACERYHDQQDVT---SNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCL 376
           W +        +   Y  ++D     S +  A+W  +IT  +IGYGD  P T+ G+ +  
Sbjct: 270 WYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSA 329

Query: 377 LTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKN 436
              ++G    AL   ++     L   E+H           ++ +N AAN+++  W  Y  
Sbjct: 330 GFALLGISFFALPAGILGSGFALKVQEQHRQKHF------EKRRNPAANLIQCVWRSYAA 383

Query: 437 TKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQ 469
            +  K +  A  + H    L+A+H     K EQ
Sbjct: 384 DE--KSVSIATWKPH----LKALHTCSPTKKEQ 410


>gi|28373065 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 1 [Homo sapiens]
          Length = 932

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 104/453 (22%), Positives = 168/453 (37%), Gaps = 77/453 (16%)

Query: 41  GGGGGASSPSAAAAAAAA----------VSSSAPEIVVSKPEHNNSNNLALYGTGGGGST 90
           GG  G    S AAAAAA           V S    ++++       + L L GT      
Sbjct: 11  GGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARG-DGLLLLGTRAATLG 69

Query: 91  GGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMV 150
           GGGGG   S  G      S   K  +       RR +  K +R+ +Y         +  V
Sbjct: 70  GGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNV--KYRRVQNY---------LYNV 118

Query: 151 IETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMT 210
           +E    W     A ++ L   CLI     + +   I  H +          A    + + 
Sbjct: 119 LERPRGWAFIYHAFVFLLVFGCLI-----LSVFSTIPEHTKL---------ASSCLLILE 164

Query: 211 YERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIA 270
           +  I    LE ++             W  RL F+  P      +D I+         LIA
Sbjct: 165 FVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCV---IDTIV---------LIA 212

Query: 271 RVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSI----SLWIIAA 326
            + ++ +K  T  +  +  AL  + F  + +    M    GT  L+ S+    S  +I A
Sbjct: 213 SIAVVSAK--TQGNIFATSALRSLRF-LQILRMVRMDRRGGTWKLLGSVVYAHSKELITA 269

Query: 327 WTV-------RACERYHDQQDVT---SNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCL 376
           W +        +   Y  ++D     S +  A+W  +IT  +IGYGD  P T+ G+ +  
Sbjct: 270 WYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSA 329

Query: 377 LTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKN 436
              ++G    AL   ++     L   E+H           ++ +N AAN+++  W  Y  
Sbjct: 330 GFALLGISFFALPAGILGSGFALKVQEQHRQKHF------EKRRNPAANLIQCVWRSYAA 383

Query: 437 TKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQ 469
            +  K +  A  + H    L+A+H     K EQ
Sbjct: 384 DE--KSVSIATWKPH----LKALHTCSPTKKEQ 410


>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
          Length = 532

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 29/59 (49%), Positives = 35/59 (59%)

Query: 48  SPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHGSSSG 106
           SP+AAAAAAAA +++A    V +   + S        GG GS GGGGG GG G GSS G
Sbjct: 454 SPAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGG 512



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 33/92 (35%), Positives = 46/92 (50%), Gaps = 2/92 (2%)

Query: 15  SNLSASRRNLHEMDSEAQPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHN 74
           S  S +  + +E  +    + P A        S  +AAAAAAAA +++A   V       
Sbjct: 422 SESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAV--HRGGG 479

Query: 75  NSNNLALYGTGGGGSTGGGGGGGGSGHGSSSG 106
           + +  A  G+GGG  +GGGGGG G G G SSG
Sbjct: 480 SGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSG 511



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 34/101 (33%), Positives = 45/101 (44%), Gaps = 8/101 (7%)

Query: 7   NGGVMRPLSNLSASRRN--LHEMDSEAQPLQPPASVGGGGGA--SSPSAAAAAAAAVSSS 62
           NG V    +++ A + N   HE+     P Q  A    G GA   S +AAAAAAA    +
Sbjct: 47  NGFVDSAAAHMGAFKLNPGAHELS----PGQSSAFTSQGPGAYPGSAAAAAAAAALGPHA 102

Query: 63  APEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHGS 103
           A     S P  N++ +      G G S  GGG  G  G G+
Sbjct: 103 AHVGSYSGPPFNSTRDFLFRSRGFGDSAPGGGQHGLFGPGA 143


>gi|122937319 even-skipped homeobox 2 [Homo sapiens]
          Length = 476

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 38/91 (41%), Positives = 47/91 (51%), Gaps = 18/91 (19%)

Query: 35  QPPASVGGGGGASSPSAAAAAAAAVSSSA-----PEIVVSKPE-----HNNSNNLA---- 80
           Q PA+  G   A+S +AAAAAAAA +SSA     P    S P      H++ +  A    
Sbjct: 345 QAPAAAAGLNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAA 404

Query: 81  ----LYGTGGGGSTGGGGGGGGSGHGSSSGT 107
               L   GGGG  GGGGGGGG G G+  G+
Sbjct: 405 AAAALGSRGGGGGGGGGGGGGGGGAGAGGGS 435



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 21/85 (24%), Positives = 34/85 (40%)

Query: 26  EMDSEAQPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTG 85
           E+ S A+  + P         +  S+      +   S   +  ++ + NN    A  G+ 
Sbjct: 91  EISSAAESRKKPGHYSEAAAEADMSSDVEVGCSALRSPGGLGAAQLKENNGKGYAESGSA 150

Query: 86  GGGSTGGGGGGGGSGHGSSSGTKSS 110
            G +T   G G GS HG S G+  S
Sbjct: 151 AGTTTSASGSGLGSLHGGSGGSGGS 175


>gi|236461942 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 3 [Homo sapiens]
          Length = 942

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 101/444 (22%), Positives = 165/444 (37%), Gaps = 77/444 (17%)

Query: 41  GGGGGASSPSAAAAAAAA----------VSSSAPEIVVSKPEHNNSNNLALYGTGGGGST 90
           GG  G    S AAAAAA           V S    ++++       + L L GT      
Sbjct: 11  GGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARG-DGLLLLGTRAATLG 69

Query: 91  GGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMV 150
           GGGGG   S  G      S   K  +       RR +  K +R+ +Y         +  V
Sbjct: 70  GGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNV--KYRRVQNY---------LYNV 118

Query: 151 IETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMT 210
           +E    W     A ++ L   CLI     + +   I  H +          A    + + 
Sbjct: 119 LERPRGWAFIYHAFVFLLVFGCLI-----LSVFSTIPEHTKL---------ASSCLLILE 164

Query: 211 YERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIA 270
           +  I    LE ++             W  RL F+  P      +D I+         LIA
Sbjct: 165 FVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCV---IDTIV---------LIA 212

Query: 271 RVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSI----SLWIIAA 326
            + ++ +K  T  +  +  AL  + F  + +    M    GT  L+ S+    S  +I A
Sbjct: 213 SIAVVSAK--TQGNIFATSALRSLRF-LQILRMVRMDRRGGTWKLLGSVVYAHSKELITA 269

Query: 327 WTV-------RACERYHDQQDVT---SNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCL 376
           W +        +   Y  ++D     S +  A+W  +IT  +IGYGD  P T+ G+ +  
Sbjct: 270 WYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSA 329

Query: 377 LTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKN 436
              ++G    AL   ++     L   E+H           ++ +N AAN+++  W  Y  
Sbjct: 330 GFALLGISFFALPAGILGSGFALKVQEQHRQKHF------EKRRNPAANLIQCVWRSYAA 383

Query: 437 TKLVKKIDHAKVRKHQRKFLQAIH 460
            +  K +  A  + H    L+A+H
Sbjct: 384 DE--KSVSIATWKPH----LKALH 401


>gi|236461719 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 2 [Homo sapiens]
          Length = 923

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 101/444 (22%), Positives = 165/444 (37%), Gaps = 77/444 (17%)

Query: 41  GGGGGASSPSAAAAAAAA----------VSSSAPEIVVSKPEHNNSNNLALYGTGGGGST 90
           GG  G    S AAAAAA           V S    ++++       + L L GT      
Sbjct: 11  GGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARG-DGLLLLGTRAATLG 69

Query: 91  GGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMV 150
           GGGGG   S  G      S   K  +       RR +  K +R+ +Y         +  V
Sbjct: 70  GGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNV--KYRRVQNY---------LYNV 118

Query: 151 IETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMT 210
           +E    W     A ++ L   CLI     + +   I  H +          A    + + 
Sbjct: 119 LERPRGWAFIYHAFVFLLVFGCLI-----LSVFSTIPEHTKL---------ASSCLLILE 164

Query: 211 YERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIA 270
           +  I    LE ++             W  RL F+  P      +D I+         LIA
Sbjct: 165 FVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCV---IDTIV---------LIA 212

Query: 271 RVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSI----SLWIIAA 326
            + ++ +K  T  +  +  AL  + F  + +    M    GT  L+ S+    S  +I A
Sbjct: 213 SIAVVSAK--TQGNIFATSALRSLRF-LQILRMVRMDRRGGTWKLLGSVVYAHSKELITA 269

Query: 327 WTV-------RACERYHDQQDVT---SNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCL 376
           W +        +   Y  ++D     S +  A+W  +IT  +IGYGD  P T+ G+ +  
Sbjct: 270 WYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSA 329

Query: 377 LTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKN 436
              ++G    AL   ++     L   E+H           ++ +N AAN+++  W  Y  
Sbjct: 330 GFALLGISFFALPAGILGSGFALKVQEQHRQKHF------EKRRNPAANLIQCVWRSYAA 383

Query: 437 TKLVKKIDHAKVRKHQRKFLQAIH 460
            +  K +  A  + H    L+A+H
Sbjct: 384 DE--KSVSIATWKPH----LKALH 401


>gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens]
          Length = 508

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 27/69 (39%), Positives = 38/69 (55%)

Query: 39  SVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGG 98
           S GG  G+S+ S  +++AAA +++A     S P  N+ +     G  GG   GGGGGGGG
Sbjct: 106 SCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGG 165

Query: 99  SGHGSSSGT 107
           S   S  G+
Sbjct: 166 SSAHSQDGS 174


>gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens]
          Length = 490

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 27/69 (39%), Positives = 38/69 (55%)

Query: 39  SVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGG 98
           S GG  G+S+ S  +++AAA +++A     S P  N+ +     G  GG   GGGGGGGG
Sbjct: 88  SCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGG 147

Query: 99  SGHGSSSGT 107
           S   S  G+
Sbjct: 148 SSAHSQDGS 156


>gi|126090909 engrailed homeobox 1 [Homo sapiens]
          Length = 392

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 31/83 (37%), Positives = 40/83 (48%), Gaps = 16/83 (19%)

Query: 35  QPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGG 94
           QP A+  G   A +P+AAAAAAAA  ++A     +KP                  TGGGG
Sbjct: 184 QPAAAGAGASKAGNPAAAAAAAAAAVAAAAAAAAAKP----------------SDTGGGG 227

Query: 95  GGGGSGHGSSSGTKSSKKKNQNI 117
            GGG+G   + GTK  +  N  I
Sbjct: 228 SGGGAGSPGAQGTKYPEHGNPAI 250


>gi|13994236 cat eye syndrome chromosome region, candidate 6 isoform
           a [Homo sapiens]
          Length = 578

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 36/108 (33%), Positives = 51/108 (47%), Gaps = 8/108 (7%)

Query: 5   RYNGGVMRPLSNLSASRRNLHEMDSEAQPL-------QPPASVGGGGGASSPSAAAAAAA 57
           R  GG   P S+  A R +  E  S ++PL        PPA VG   G +  + +++AA 
Sbjct: 60  RRGGGGGSPSSSTGAEREDDDESLSVSKPLVPNAALLGPPAQVGAPAGPAPVAFSSSAAT 119

Query: 58  AVSSSAPEIVVSKPEHNNSNNLALYGTGGGGS-TGGGGGGGGSGHGSS 104
           + S+S P    S    +     A    GG GS + GG GG G+G G+S
Sbjct: 120 SSSTSTPTSSCSMTAADFGGGAAAGAVGGPGSRSAGGAGGTGTGSGAS 167



 Score = 33.5 bits (75), Expect = 0.55
 Identities = 20/67 (29%), Positives = 28/67 (41%)

Query: 37  PASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGG 96
           P SV    G+  P  AAA    +          +   ++S + +    GGGG  GGGGG 
Sbjct: 8   PRSVSSASGSFPPPPAAARLQPLFLRGGSFRGRRGSGDSSTSTSTSRGGGGGRRGGGGGS 67

Query: 97  GGSGHGS 103
             S  G+
Sbjct: 68  PSSSTGA 74


>gi|22748877 basic helix-loop-helix domain containing, class B, 5
           [Homo sapiens]
          Length = 381

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 40/117 (34%), Positives = 51/117 (43%), Gaps = 22/117 (18%)

Query: 26  EMDSEAQPLQPPASVG-GGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGT 84
           E+   A    P AS G GGGGA +    + A     +S P                L G 
Sbjct: 157 ELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPG-------------GLGGG 203

Query: 85  GGGGST-----GGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSD 136
           GGGGS+     GGGG G GSG  SSS + SSKK  +    +L        +R+R+ D
Sbjct: 204 GGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQKALRLNINA---RERRRMHD 257



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 13/16 (81%), Positives = 13/16 (81%)

Query: 83 GTGGGGSTGGGGGGGG 98
          G GGGGS G GGGGGG
Sbjct: 81 GGGGGGSAGSGGGGGG 96



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 18/45 (40%), Positives = 22/45 (48%)

Query: 58  AVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHG 102
           A SSS+P       +   +  L     GGGG + G GGGGG G G
Sbjct: 55  ASSSSSPLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVG 99


>gi|238859557 regulatory factor X1 [Homo sapiens]
          Length = 979

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 46  ASSPSAAAAAAAAVSSSAPEIVVSKPEHNN--SNNLALYGTGGGGSTGGGGGGGGSGHGS 103
           A+S + A++ +  +  S  ++V S        SN+    G+GGGG  GGGGGGGGSG   
Sbjct: 345 ATSQAVASSGSMPMYVSGSQVVASSTSTGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTG 404

Query: 104 SSGTKSSKKKNQNIGYKLGHRRALFEKRKRLS 135
             G+ +     Q  GY LG     +    R S
Sbjct: 405 GGGSGAGTYVIQG-GYMLGSASQSYSHTTRAS 435



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 28/68 (41%), Positives = 35/68 (51%), Gaps = 4/68 (5%)

Query: 44  GGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYG----TGGGGSTGGGGGGGGS 99
           G A+  S  A + A  SS +  + VS  +   S+     G    +GGGGS GGGGGGGG 
Sbjct: 336 GTATQVSTPATSQAVASSGSMPMYVSGSQVVASSTSTGAGASNSSGGGGSGGGGGGGGGG 395

Query: 100 GHGSSSGT 107
           G G S  T
Sbjct: 396 GGGGSGST 403


>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
          Length = 920

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 8/64 (12%)

Query: 43  GGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHG 102
           G GA+ P + + +AAA SS        + +        LYG  GGG  GGGGGGGG G G
Sbjct: 416 GAGAAGPGSGSPSAAASSSWHTLFTAEEGQ--------LYGPCGGGGGGGGGGGGGGGGG 467

Query: 103 SSSG 106
              G
Sbjct: 468 GGGG 471



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 27/64 (42%), Positives = 34/64 (53%), Gaps = 8/64 (12%)

Query: 43  GGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHG 102
           G G+ SPSAAA+++     +A E  +  P           G GGGG  GGGGGGGG G G
Sbjct: 421 GPGSGSPSAAASSSWHTLFTAEEGQLYGPCGG--------GGGGGGGGGGGGGGGGGGGG 472

Query: 103 SSSG 106
             +G
Sbjct: 473 GEAG 476


>gi|26638655 potassium voltage-gated channel KQT-like protein 4
           isoform b [Homo sapiens]
          Length = 641

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 88/425 (20%), Positives = 150/425 (35%), Gaps = 102/425 (24%)

Query: 36  PPASVG-GGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGST---- 90
           PP  +G G     +P A   A  AV S   E                   GGGGS     
Sbjct: 5   PPRRLGLGPPPGDAPRAELVALTAVQSEQGE------------------AGGGGSPRRLG 46

Query: 91  --------GGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFG 142
                   G    G GSG GS+ G +SS               A  ++ +RL ++     
Sbjct: 47  LLGSPLPPGAPLPGPGSGSGSACGQRSS---------------AAHKRYRRLQNW----- 86

Query: 143 MFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGA 202
               V  V+E    W       ++ L   CL+      L  L  +   +E+        A
Sbjct: 87  ----VYNVLERPRGWAFVYHVFIFLLVFSCLV------LSVLSTIQEHQEL--------A 128

Query: 203 DDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPM 262
           ++  + + +  I    LE +V             W  R  F+  P      +  + S+ +
Sbjct: 129 NECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAV 188

Query: 263 FLRLYLIARVMLLHSKLFTDASSRS---IGALNKINFNTRFVMKTLMTICPGTVLLVFS- 318
                           +F  ++ RS   +  L  +  + R     L+    G+V+   S 
Sbjct: 189 I--------AAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLL----GSVVYAHSK 236

Query: 319 --ISLW-------IIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTY 369
             I+ W       I A++ V   E+  D     S++  ++W  +IT  +IGYGD  P+T+
Sbjct: 237 ELITAWYIGFLVLIFASFLVYLAEK--DANSDFSSYADSLWWGTITLTTIGYGDKTPHTW 294

Query: 370 CGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRE 429
            G+ +     ++G    AL   ++     L   E+H           ++ +  AAN+++ 
Sbjct: 295 LGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHF------EKRRMPAANLIQA 348

Query: 430 TWLIY 434
            W +Y
Sbjct: 349 AWRLY 353


>gi|26638653 potassium voltage-gated channel KQT-like protein 4
           isoform a [Homo sapiens]
          Length = 695

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 88/425 (20%), Positives = 150/425 (35%), Gaps = 102/425 (24%)

Query: 36  PPASVG-GGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGST---- 90
           PP  +G G     +P A   A  AV S   E                   GGGGS     
Sbjct: 5   PPRRLGLGPPPGDAPRAELVALTAVQSEQGE------------------AGGGGSPRRLG 46

Query: 91  --------GGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFG 142
                   G    G GSG GS+ G +SS               A  ++ +RL ++     
Sbjct: 47  LLGSPLPPGAPLPGPGSGSGSACGQRSS---------------AAHKRYRRLQNW----- 86

Query: 143 MFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGA 202
               V  V+E    W       ++ L   CL+      L  L  +   +E+        A
Sbjct: 87  ----VYNVLERPRGWAFVYHVFIFLLVFSCLV------LSVLSTIQEHQEL--------A 128

Query: 203 DDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPM 262
           ++  + + +  I    LE +V             W  R  F+  P      +  + S+ +
Sbjct: 129 NECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAV 188

Query: 263 FLRLYLIARVMLLHSKLFTDASSRS---IGALNKINFNTRFVMKTLMTICPGTVLLVFS- 318
                           +F  ++ RS   +  L  +  + R     L+    G+V+   S 
Sbjct: 189 I--------AAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLL----GSVVYAHSK 236

Query: 319 --ISLW-------IIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTY 369
             I+ W       I A++ V   E+  D     S++  ++W  +IT  +IGYGD  P+T+
Sbjct: 237 ELITAWYIGFLVLIFASFLVYLAEK--DANSDFSSYADSLWWGTITLTTIGYGDKTPHTW 294

Query: 370 CGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRE 429
            G+ +     ++G    AL   ++     L   E+H           ++ +  AAN+++ 
Sbjct: 295 LGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHF------EKRRMPAANLIQA 348

Query: 430 TWLIY 434
            W +Y
Sbjct: 349 AWRLY 353


>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
          Length = 558

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 33/90 (36%), Positives = 40/90 (44%), Gaps = 11/90 (12%)

Query: 29  SEAQPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGG 88
           S A  + PPAS G       P A+AAAAAA  +S                      GGGG
Sbjct: 39  SPAPSIGPPASSGPTLFRPEPIASAAAAAATVTST-----------GGGGGGGGSGGGGG 87

Query: 89  STGGGGGGGGSGHGSSSGTKSSKKKNQNIG 118
           S+G GGGGGG G GS+     +   N + G
Sbjct: 88  SSGNGGGGGGGGGGSNCNPNLAAASNGSGG 117



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 6/80 (7%)

Query: 33  PLQPPASVGGGGGASSPSAAAAAAAAV------SSSAPEIVVSKPEHNNSNNLALYGTGG 86
           P QPP S       ++ S ++A ++        +SS P +   +P  + +   A   + G
Sbjct: 15  PPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTG 74

Query: 87  GGSTGGGGGGGGSGHGSSSG 106
           GG  GGG GGGG   G+  G
Sbjct: 75  GGGGGGGSGGGGGSSGNGGG 94



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 9/76 (11%)

Query: 41  GGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSG 100
           GGGGG+S            S+  P +  +    N S      G GGGG + GGG    + 
Sbjct: 83  GGGGGSSGNGGGGGGGGGGSNCNPNLAAAS---NGS------GGGGGGISAGGGVASSTP 133

Query: 101 HGSSSGTKSSKKKNQN 116
             +S+G+ SS   + +
Sbjct: 134 INASTGSSSSSSSSSS 149



 Score = 32.7 bits (73), Expect = 0.94
 Identities = 25/83 (30%), Positives = 31/83 (37%), Gaps = 20/83 (24%)

Query: 42  GGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGG--- 98
           GGGG SS +          S            N + NLA    G GG  GG   GGG   
Sbjct: 83  GGGGGSSGNGGGGGGGGGGS------------NCNPNLAAASNGSGGGGGGISAGGGVAS 130

Query: 99  -----SGHGSSSGTKSSKKKNQN 116
                +  GSSS + SS   + +
Sbjct: 131 STPINASTGSSSSSSSSSSSSSS 153


>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
          Length = 706

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 33/90 (36%), Positives = 40/90 (44%), Gaps = 11/90 (12%)

Query: 29  SEAQPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGG 88
           S A  + PPAS G       P A+AAAAAA  +S                      GGGG
Sbjct: 39  SPAPSIGPPASSGPTLFRPEPIASAAAAAATVTST-----------GGGGGGGGSGGGGG 87

Query: 89  STGGGGGGGGSGHGSSSGTKSSKKKNQNIG 118
           S+G GGGGGG G GS+     +   N + G
Sbjct: 88  SSGNGGGGGGGGGGSNCNPNLAAASNGSGG 117



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 6/80 (7%)

Query: 33  PLQPPASVGGGGGASSPSAAAAAAAAV------SSSAPEIVVSKPEHNNSNNLALYGTGG 86
           P QPP S       ++ S ++A ++        +SS P +   +P  + +   A   + G
Sbjct: 15  PPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTG 74

Query: 87  GGSTGGGGGGGGSGHGSSSG 106
           GG  GGG GGGG   G+  G
Sbjct: 75  GGGGGGGSGGGGGSSGNGGG 94



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 9/76 (11%)

Query: 41  GGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSG 100
           GGGGG+S            S+  P +  +    N S      G GGGG + GGG    + 
Sbjct: 83  GGGGGSSGNGGGGGGGGGGSNCNPNLAAAS---NGS------GGGGGGISAGGGVASSTP 133

Query: 101 HGSSSGTKSSKKKNQN 116
             +S+G+ SS   + +
Sbjct: 134 INASTGSSSSSSSSSS 149



 Score = 32.7 bits (73), Expect = 0.94
 Identities = 25/83 (30%), Positives = 31/83 (37%), Gaps = 20/83 (24%)

Query: 42  GGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGG--- 98
           GGGG SS +          S            N + NLA    G GG  GG   GGG   
Sbjct: 83  GGGGGSSGNGGGGGGGGGGS------------NCNPNLAAASNGSGGGGGGISAGGGVAS 130

Query: 99  -----SGHGSSSGTKSSKKKNQN 116
                +  GSSS + SS   + +
Sbjct: 131 STPINASTGSSSSSSSSSSSSSS 153


>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
          Length = 504

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 33/90 (36%), Positives = 40/90 (44%), Gaps = 11/90 (12%)

Query: 29  SEAQPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGG 88
           S A  + PPAS G       P A+AAAAAA  +S                      GGGG
Sbjct: 39  SPAPSIGPPASSGPTLFRPEPIASAAAAAATVTST-----------GGGGGGGGSGGGGG 87

Query: 89  STGGGGGGGGSGHGSSSGTKSSKKKNQNIG 118
           S+G GGGGGG G GS+     +   N + G
Sbjct: 88  SSGNGGGGGGGGGGSNCNPNLAAASNGSGG 117



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 6/80 (7%)

Query: 33  PLQPPASVGGGGGASSPSAAAAAAAAV------SSSAPEIVVSKPEHNNSNNLALYGTGG 86
           P QPP S       ++ S ++A ++        +SS P +   +P  + +   A   + G
Sbjct: 15  PPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTG 74

Query: 87  GGSTGGGGGGGGSGHGSSSG 106
           GG  GGG GGGG   G+  G
Sbjct: 75  GGGGGGGSGGGGGSSGNGGG 94



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 9/76 (11%)

Query: 41  GGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSG 100
           GGGGG+S            S+  P +  +    N S      G GGGG + GGG    + 
Sbjct: 83  GGGGGSSGNGGGGGGGGGGSNCNPNLAAAS---NGS------GGGGGGISAGGGVASSTP 133

Query: 101 HGSSSGTKSSKKKNQN 116
             +S+G+ SS   + +
Sbjct: 134 INASTGSSSSSSSSSS 149



 Score = 32.7 bits (73), Expect = 0.94
 Identities = 25/83 (30%), Positives = 31/83 (37%), Gaps = 20/83 (24%)

Query: 42  GGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGG--- 98
           GGGG SS +          S            N + NLA    G GG  GG   GGG   
Sbjct: 83  GGGGGSSGNGGGGGGGGGGS------------NCNPNLAAASNGSGGGGGGISAGGGVAS 130

Query: 99  -----SGHGSSSGTKSSKKKNQN 116
                +  GSSS + SS   + +
Sbjct: 131 STPINASTGSSSSSSSSSSSSSS 153


>gi|26051268 potassium voltage-gated channel KQT-like protein 2
           isoform e [Homo sapiens]
          Length = 393

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 33/141 (23%), Positives = 63/141 (44%), Gaps = 9/141 (6%)

Query: 323 IIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMG 382
           I+A++ V   E+   + D    +  A+W   IT  +IGYGD  P T+ G+ +     ++G
Sbjct: 244 ILASFLVYLAEK--GENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIG 301

Query: 383 AGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKK 442
               AL   ++     L   E+H           ++ +N AA +++  W  Y  T L + 
Sbjct: 302 VSFFALPAGILGSGFALKVQEQHRQKHF------EKRRNPAAGLIQSAWRFYA-TNLSRT 354

Query: 443 IDHAKVRKHQRKFLQAIHQLR 463
             H+  + ++R     +++ R
Sbjct: 355 DLHSTWQYYERTVTVPMYRYR 375


>gi|26051260 potassium voltage-gated channel KQT-like protein 2
           isoform c [Homo sapiens]
          Length = 844

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 33/140 (23%), Positives = 63/140 (45%), Gaps = 9/140 (6%)

Query: 323 IIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMG 382
           I+A++ V   E+   + D    +  A+W   IT  +IGYGD  P T+ G+ +     ++G
Sbjct: 244 ILASFLVYLAEK--GENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIG 301

Query: 383 AGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKK 442
               AL   ++     L   E+H           ++ +N AA +++  W  Y  T L + 
Sbjct: 302 VSFFALPAGILGSGFALKVQEQHRQKHF------EKRRNPAAGLIQSAWRFYA-TNLSRT 354

Query: 443 IDHAKVRKHQRKFLQAIHQL 462
             H+  + ++R     +++L
Sbjct: 355 DLHSTWQYYERTVTVPMYRL 374


>gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]
          Length = 409

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 29/66 (43%), Positives = 36/66 (54%), Gaps = 4/66 (6%)

Query: 42  GGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGH 101
           GG     P  +A  + +  SSAP I  S    ++S+N    G GGGG  GGGGGGG S  
Sbjct: 17  GGSLHVEPKYSALHSTSPGSSAP-IAPSASSPSSSSNA---GGGGGGGGGGGGGGGRSSS 72

Query: 102 GSSSGT 107
            SSSG+
Sbjct: 73  SSSSGS 78


>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
           member 2 [Homo sapiens]
          Length = 630

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 45/184 (24%), Positives = 78/184 (42%), Gaps = 30/184 (16%)

Query: 214 IFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPS------TTTADVDIILSIPMFLRLY 267
           + F CL+     I      +T  +  RLA   APS      +  + +D++  +P ++ L 
Sbjct: 227 VAFFCLDTACVMI------FTVEYLLRLAA--APSRYRFVRSVMSIIDVVAILPYYIGLV 278

Query: 268 LI-------ARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSIS 320
           +        A V L   ++F       I   ++ +   R +  TL +       L+FS++
Sbjct: 279 MTDNEDVSGAFVTLRVFRVFR------IFKFSRHSQGLRILGYTLKSCASELGFLLFSLT 332

Query: 321 LWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGK---GVCLL 377
           + II   TV             ++   A W   +T  ++GYGDMVP T  GK    +C L
Sbjct: 333 MAIIIFATVMFYAEKGSSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSL 392

Query: 378 TGIM 381
           +G++
Sbjct: 393 SGVL 396


>gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo
           sapiens]
          Length = 872

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 86/419 (20%), Positives = 149/419 (35%), Gaps = 77/419 (18%)

Query: 41  GGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGG---GGG 97
           GGGGGA++P+   AAAA        +    P       LAL    G G+   G     GG
Sbjct: 20  GGGGGAANPAGGDAAAAGDEERKVGLA---PGDVEQVTLAL----GAGADKDGTLLLEGG 72

Query: 98  GSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSW 157
           G   G        ++  Q IG  L  +  L    KR  + A    +  ++   +E    W
Sbjct: 73  GRDEGQ-------RRTPQGIG--LLAKTPLSRPVKR--NNAKYRRIQTLIYDALERPRGW 121

Query: 158 GAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFI 217
                A ++ + L CLI         L ++   +E +       + DW + +    IF  
Sbjct: 122 ALLYHALVFLIVLGCLI---------LAVLTTFKEYETV-----SGDWLLLLETFAIFIF 167

Query: 218 CLEILV-------CAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMF------- 263
             E  +       C  +         W  RL F+  P        +I S+P+        
Sbjct: 168 GAEFALRIWAAGCCCRYK-------GWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGN 220

Query: 264 --------LRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLL 315
                   LR   I R++ +  +  T     S    +     T + +  L        L+
Sbjct: 221 VLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFL-------TLI 273

Query: 316 VFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVC 375
           + S  ++++         +  + ++    +  A+W   IT  +IGYGD  P T+ G+ + 
Sbjct: 274 LSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIA 333

Query: 376 LLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIY 434
               ++G    AL   ++   L L   E+H           ++ +  AA +++  W  Y
Sbjct: 334 ATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHF------EKRRKPAAELIQAAWRYY 386



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 4/33 (12%)

Query: 83  GTGGGGSTGGGGGGGGS----GHGSSSGTKSSK 111
           G  GGG  GGGGGGG +    G  +++G +  K
Sbjct: 10  GAAGGGGDGGGGGGGAANPAGGDAAAAGDEERK 42



 Score = 29.6 bits (65), Expect = 7.9
 Identities = 11/29 (37%), Positives = 16/29 (55%)

Query: 85  GGGGSTGGGGGGGGSGHGSSSGTKSSKKK 113
           GGGG  GGGGGG  +  G  +     +++
Sbjct: 13  GGGGDGGGGGGGAANPAGGDAAAAGDEER 41


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,268,713
Number of Sequences: 37866
Number of extensions: 905003
Number of successful extensions: 21063
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 385
Number of HSP's successfully gapped in prelim test: 257
Number of HSP's that attempted gapping in prelim test: 10727
Number of HSP's gapped (non-prelim): 5369
length of query: 579
length of database: 18,247,518
effective HSP length: 108
effective length of query: 471
effective length of database: 14,157,990
effective search space: 6668413290
effective search space used: 6668413290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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