BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|254028267 myosin 1H [Homo sapiens] (1022 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|254028267 myosin 1H [Homo sapiens] 2054 0.0 gi|124494247 myosin IC isoform b [Homo sapiens] 1286 0.0 gi|124494238 myosin IC isoform a [Homo sapiens] 1286 0.0 gi|124494240 myosin IC isoform c [Homo sapiens] 1286 0.0 gi|44889481 myosin IB isoform 2 [Homo sapiens] 758 0.0 gi|4885503 myosin IA [Homo sapiens] 716 0.0 gi|194328685 myosin IB isoform 1 [Homo sapiens] 709 0.0 gi|240120050 myosin IB isoform 1 [Homo sapiens] 709 0.0 gi|51100974 myosin ID [Homo sapiens] 667 0.0 gi|239582755 myosin IG [Homo sapiens] 612 e-175 gi|27544941 myosin IF [Homo sapiens] 596 e-170 gi|55956916 myosin IE [Homo sapiens] 582 e-166 gi|154354979 myosin X [Homo sapiens] 474 e-133 gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 473 e-133 gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 473 e-133 gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 473 e-133 gi|122937512 myosin VIIB [Homo sapiens] 467 e-131 gi|118402590 myosin XV [Homo sapiens] 460 e-129 gi|215982794 myosin VA isoform 2 [Homo sapiens] 457 e-128 gi|215982791 myosin VA isoform 1 [Homo sapiens] 457 e-128 gi|153945715 myosin VC [Homo sapiens] 457 e-128 gi|122937345 myosin VB [Homo sapiens] 451 e-126 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 444 e-124 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 434 e-121 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 429 e-120 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 429 e-120 gi|156104908 myosin heavy chain 6 [Homo sapiens] 429 e-120 gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 429 e-120 gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 429 e-120 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 428 e-119 >gi|254028267 myosin 1H [Homo sapiens] Length = 1022 Score = 2054 bits (5322), Expect = 0.0 Identities = 1022/1022 (100%), Positives = 1022/1022 (100%) Query: 1 MEGALTARDKVGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGI 60 MEGALTARDKVGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGI Sbjct: 1 MEGALTARDKVGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGI 60 Query: 61 YTVSQMELYQGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILE 120 YTVSQMELYQGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILE Sbjct: 61 YTVSQMELYQGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILE 120 Query: 121 YFAVTCPMTQSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGG 180 YFAVTCPMTQSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGG Sbjct: 121 YFAVTCPMTQSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGG 180 Query: 181 HIISYLIEKSRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKE 240 HIISYLIEKSRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKE Sbjct: 181 HIISYLIEKSRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKE 240 Query: 241 SSISDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEI 300 SSISDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEI Sbjct: 241 SSISDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEI 300 Query: 301 KWIAKLLGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVN 360 KWIAKLLGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVN Sbjct: 301 KWIAKLLGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVN 360 Query: 361 KINSSLVNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAE 420 KINSSLVNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAE Sbjct: 361 KINSSLVNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAE 420 Query: 421 YEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKH 480 YEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKH Sbjct: 421 YEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKH 480 Query: 481 AHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNI 540 AHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNI Sbjct: 481 AHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNI 540 Query: 541 ILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDF 600 ILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDF Sbjct: 541 ILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDF 600 Query: 601 LIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKY 660 LIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKY Sbjct: 601 LIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKY 660 Query: 661 IGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQA 720 IGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQA Sbjct: 661 IGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQA 720 Query: 721 AIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIVFVRKNYILNL 780 AIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIVFVRKNYILNL Sbjct: 721 AIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIVFVRKNYILNL 780 Query: 781 RYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQKVVTSEI 840 RYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQKVVTSEI Sbjct: 781 RYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQKVVTSEI 840 Query: 841 FRGRKDGYTESLNQPFVNSRIDEGDINPKVLQLISHEKIQYGVPVIKYDRKGFKARQRQL 900 FRGRKDGYTESLNQPFVNSRIDEGDINPKVLQLISHEKIQYGVPVIKYDRKGFKARQRQL Sbjct: 841 FRGRKDGYTESLNQPFVNSRIDEGDINPKVLQLISHEKIQYGVPVIKYDRKGFKARQRQL 900 Query: 901 ILTQKAAYVVELAKIKQKIEYSALKGVSTSNLSDGILVIHVSPEDSKQKGDAVLQCGHVF 960 ILTQKAAYVVELAKIKQKIEYSALKGVSTSNLSDGILVIHVSPEDSKQKGDAVLQCGHVF Sbjct: 901 ILTQKAAYVVELAKIKQKIEYSALKGVSTSNLSDGILVIHVSPEDSKQKGDAVLQCGHVF 960 Query: 961 EAVTKLVMLVKKENIVNVVQGSLQFFISPGKEGTIVFDTGLEEQVYKNKNGQLTVVSVRR 1020 EAVTKLVMLVKKENIVNVVQGSLQFFISPGKEGTIVFDTGLEEQVYKNKNGQLTVVSVRR Sbjct: 961 EAVTKLVMLVKKENIVNVVQGSLQFFISPGKEGTIVFDTGLEEQVYKNKNGQLTVVSVRR 1020 Query: 1021 KS 1022 KS Sbjct: 1021 KS 1022 >gi|124494247 myosin IC isoform b [Homo sapiens] Length = 1044 Score = 1286 bits (3329), Expect = 0.0 Identities = 624/1027 (60%), Positives = 794/1027 (77%), Gaps = 5/1027 (0%) Query: 1 MEGALTARDKVGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGI 60 ME ALTARD+VGVQDFVLL+ +TSE+AF++NLR+RF ENLIYTYIG +LVSVNPY++L I Sbjct: 17 MESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQI 76 Query: 61 YTVSQMELYQGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILE 120 Y+ ME Y+GV+F+E+PPH++A+AD YR + E + ++ISGESGAGKTEA+K++L+ Sbjct: 77 YSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQ 136 Query: 121 YFAVTCPMTQSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGG 180 ++A TCP + RDRLL SNPVLEAFGNA+TLRNDNSSRFGKYMD+QFDF+G PVGG Sbjct: 137 FYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGG 196 Query: 181 HIISYLIEKSRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKE 240 HI+SYL+EKSRVV+QN GERNFHIFYQLL GGEEE L LGLER+PQ Y YL +G CAK Sbjct: 197 HILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKV 256 Query: 241 SSISDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEI 300 SSI+DK+DWK V A +VIDFTE ++E+L I+ASVLHLGNI F +++ A + +++ Sbjct: 257 SSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQL 316 Query: 301 KWIAKLLGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVN 360 K++ +LL V S L EALTHRKI AK EE++ PL LE + YARDA+AKAVY RTFTWLV Sbjct: 317 KYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVG 376 Query: 361 KINSSLVNKD-----FTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLK 415 KIN SL +KD + TV+GLLDIYGFEVF N FEQFCINYCNEKLQQL IE TLK Sbjct: 377 KINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLK 436 Query: 416 AEQAEYEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEE 475 +EQ EYE EGI WEP++YFNNKIICDLVEE+ KGIISILDEEC+RPG ATDL+FLEKLE+ Sbjct: 437 SEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLED 496 Query: 476 KVGKHAHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLC 535 V H HF T KLA + RK +G EFRLLHYAGEVTY GFL+KNNDLL+R+LKE +C Sbjct: 497 TVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMC 556 Query: 536 KSKNIILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPS 595 SKN I+ +CF +EL +++RP TV TQFK SL L+E L SKEP+Y+RCIKPND K+P Sbjct: 557 SSKNPIMSQCFDRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG 616 Query: 596 KFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVE 655 +FD+ LIRHQ+KYLGL+E+LRVRRAGFAYRRKYE FLQRYKSLCP+TWP W G P +GV Sbjct: 617 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA 676 Query: 656 RLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYV 715 L++++GYKPEEYK+G+TKIFIRFP+TLFATEDA E + L +IQA ++ R++++ Sbjct: 677 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL 736 Query: 716 KKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIVFVRKN 775 + +++AI +++ WRG L R+ +RKWA + IR+ I+GF+ R+ P CP+N F+ VR + Sbjct: 737 RVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTS 796 Query: 776 YILNLRYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQKV 835 ++LNLR LP+ VLD SW PP L AS+LLR++C++N+V KYCR I+ E K +QQK Sbjct: 797 FLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKA 856 Query: 836 VTSEIFRGRKDGYTESLNQPFVNSRIDEGDINPKVLQLISHEKIQYGVPVIKYDRKGFKA 895 V SEIF+G+KD Y +S+ + F+++R+ +I+P+VLQ + E IQY VPV+KYDRKG+K Sbjct: 857 VASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQALGSEPIQYAVPVVKYDRKGYKP 916 Query: 896 RQRQLILTQKAAYVVELAKIKQKIEYSALKGVSTSNLSDGILVIHVSPEDSKQKGDAVLQ 955 R RQL+LT A +VE AK+KQ+I+Y+ L G+S S+LSD + V+HV D+KQKGD VLQ Sbjct: 917 RSRQLLLTPNAVVIVEDAKVKQRIDYANLTGISVSSLSDSLFVLHVQRADNKQKGDVVLQ 976 Query: 956 CGHVFEAVTKLVMLVKKENIVNVVQGSLQFFISPGKEGTIVFDTGLEEQVYKNKNGQLTV 1015 HV E +TK + + N +N+ QGS+ F PG++GTI F G E + K KNG L V Sbjct: 977 SDHVIETLTKTALSANRVNSININQGSITFAGGPGRDGTIDFTPGSELLITKAKNGHLAV 1036 Query: 1016 VSVRRKS 1022 V+ R S Sbjct: 1037 VAPRLNS 1043 >gi|124494238 myosin IC isoform a [Homo sapiens] Length = 1063 Score = 1286 bits (3329), Expect = 0.0 Identities = 624/1027 (60%), Positives = 794/1027 (77%), Gaps = 5/1027 (0%) Query: 1 MEGALTARDKVGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGI 60 ME ALTARD+VGVQDFVLL+ +TSE+AF++NLR+RF ENLIYTYIG +LVSVNPY++L I Sbjct: 36 MESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQI 95 Query: 61 YTVSQMELYQGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILE 120 Y+ ME Y+GV+F+E+PPH++A+AD YR + E + ++ISGESGAGKTEA+K++L+ Sbjct: 96 YSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQ 155 Query: 121 YFAVTCPMTQSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGG 180 ++A TCP + RDRLL SNPVLEAFGNA+TLRNDNSSRFGKYMD+QFDF+G PVGG Sbjct: 156 FYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGG 215 Query: 181 HIISYLIEKSRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKE 240 HI+SYL+EKSRVV+QN GERNFHIFYQLL GGEEE L LGLER+PQ Y YL +G CAK Sbjct: 216 HILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKV 275 Query: 241 SSISDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEI 300 SSI+DK+DWK V A +VIDFTE ++E+L I+ASVLHLGNI F +++ A + +++ Sbjct: 276 SSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQL 335 Query: 301 KWIAKLLGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVN 360 K++ +LL V S L EALTHRKI AK EE++ PL LE + YARDA+AKAVY RTFTWLV Sbjct: 336 KYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVG 395 Query: 361 KINSSLVNKD-----FTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLK 415 KIN SL +KD + TV+GLLDIYGFEVF N FEQFCINYCNEKLQQL IE TLK Sbjct: 396 KINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLK 455 Query: 416 AEQAEYEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEE 475 +EQ EYE EGI WEP++YFNNKIICDLVEE+ KGIISILDEEC+RPG ATDL+FLEKLE+ Sbjct: 456 SEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLED 515 Query: 476 KVGKHAHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLC 535 V H HF T KLA + RK +G EFRLLHYAGEVTY GFL+KNNDLL+R+LKE +C Sbjct: 516 TVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMC 575 Query: 536 KSKNIILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPS 595 SKN I+ +CF +EL +++RP TV TQFK SL L+E L SKEP+Y+RCIKPND K+P Sbjct: 576 SSKNPIMSQCFDRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG 635 Query: 596 KFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVE 655 +FD+ LIRHQ+KYLGL+E+LRVRRAGFAYRRKYE FLQRYKSLCP+TWP W G P +GV Sbjct: 636 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA 695 Query: 656 RLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYV 715 L++++GYKPEEYK+G+TKIFIRFP+TLFATEDA E + L +IQA ++ R++++ Sbjct: 696 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL 755 Query: 716 KKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIVFVRKN 775 + +++AI +++ WRG L R+ +RKWA + IR+ I+GF+ R+ P CP+N F+ VR + Sbjct: 756 RVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTS 815 Query: 776 YILNLRYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQKV 835 ++LNLR LP+ VLD SW PP L AS+LLR++C++N+V KYCR I+ E K +QQK Sbjct: 816 FLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKA 875 Query: 836 VTSEIFRGRKDGYTESLNQPFVNSRIDEGDINPKVLQLISHEKIQYGVPVIKYDRKGFKA 895 V SEIF+G+KD Y +S+ + F+++R+ +I+P+VLQ + E IQY VPV+KYDRKG+K Sbjct: 876 VASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQALGSEPIQYAVPVVKYDRKGYKP 935 Query: 896 RQRQLILTQKAAYVVELAKIKQKIEYSALKGVSTSNLSDGILVIHVSPEDSKQKGDAVLQ 955 R RQL+LT A +VE AK+KQ+I+Y+ L G+S S+LSD + V+HV D+KQKGD VLQ Sbjct: 936 RSRQLLLTPNAVVIVEDAKVKQRIDYANLTGISVSSLSDSLFVLHVQRADNKQKGDVVLQ 995 Query: 956 CGHVFEAVTKLVMLVKKENIVNVVQGSLQFFISPGKEGTIVFDTGLEEQVYKNKNGQLTV 1015 HV E +TK + + N +N+ QGS+ F PG++GTI F G E + K KNG L V Sbjct: 996 SDHVIETLTKTALSANRVNSININQGSITFAGGPGRDGTIDFTPGSELLITKAKNGHLAV 1055 Query: 1016 VSVRRKS 1022 V+ R S Sbjct: 1056 VAPRLNS 1062 >gi|124494240 myosin IC isoform c [Homo sapiens] Length = 1028 Score = 1286 bits (3329), Expect = 0.0 Identities = 624/1027 (60%), Positives = 794/1027 (77%), Gaps = 5/1027 (0%) Query: 1 MEGALTARDKVGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGI 60 ME ALTARD+VGVQDFVLL+ +TSE+AF++NLR+RF ENLIYTYIG +LVSVNPY++L I Sbjct: 1 MESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQI 60 Query: 61 YTVSQMELYQGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILE 120 Y+ ME Y+GV+F+E+PPH++A+AD YR + E + ++ISGESGAGKTEA+K++L+ Sbjct: 61 YSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQ 120 Query: 121 YFAVTCPMTQSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGG 180 ++A TCP + RDRLL SNPVLEAFGNA+TLRNDNSSRFGKYMD+QFDF+G PVGG Sbjct: 121 FYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGG 180 Query: 181 HIISYLIEKSRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKE 240 HI+SYL+EKSRVV+QN GERNFHIFYQLL GGEEE L LGLER+PQ Y YL +G CAK Sbjct: 181 HILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKV 240 Query: 241 SSISDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEI 300 SSI+DK+DWK V A +VIDFTE ++E+L I+ASVLHLGNI F +++ A + +++ Sbjct: 241 SSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQL 300 Query: 301 KWIAKLLGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVN 360 K++ +LL V S L EALTHRKI AK EE++ PL LE + YARDA+AKAVY RTFTWLV Sbjct: 301 KYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVG 360 Query: 361 KINSSLVNKD-----FTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLK 415 KIN SL +KD + TV+GLLDIYGFEVF N FEQFCINYCNEKLQQL IE TLK Sbjct: 361 KINRSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLK 420 Query: 416 AEQAEYEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEE 475 +EQ EYE EGI WEP++YFNNKIICDLVEE+ KGIISILDEEC+RPG ATDL+FLEKLE+ Sbjct: 421 SEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLED 480 Query: 476 KVGKHAHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLC 535 V H HF T KLA + RK +G EFRLLHYAGEVTY GFL+KNNDLL+R+LKE +C Sbjct: 481 TVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMC 540 Query: 536 KSKNIILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPS 595 SKN I+ +CF +EL +++RP TV TQFK SL L+E L SKEP+Y+RCIKPND K+P Sbjct: 541 SSKNPIMSQCFDRSELSDKKRPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG 600 Query: 596 KFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVE 655 +FD+ LIRHQ+KYLGL+E+LRVRRAGFAYRRKYE FLQRYKSLCP+TWP W G P +GV Sbjct: 601 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA 660 Query: 656 RLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYV 715 L++++GYKPEEYK+G+TKIFIRFP+TLFATEDA E + L +IQA ++ R++++ Sbjct: 661 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL 720 Query: 716 KKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIVFVRKN 775 + +++AI +++ WRG L R+ +RKWA + IR+ I+GF+ R+ P CP+N F+ VR + Sbjct: 721 RVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTS 780 Query: 776 YILNLRYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQKV 835 ++LNLR LP+ VLD SW PP L AS+LLR++C++N+V KYCR I+ E K +QQK Sbjct: 781 FLLNLRRQLPQNVLDTSWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKA 840 Query: 836 VTSEIFRGRKDGYTESLNQPFVNSRIDEGDINPKVLQLISHEKIQYGVPVIKYDRKGFKA 895 V SEIF+G+KD Y +S+ + F+++R+ +I+P+VLQ + E IQY VPV+KYDRKG+K Sbjct: 841 VASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQALGSEPIQYAVPVVKYDRKGYKP 900 Query: 896 RQRQLILTQKAAYVVELAKIKQKIEYSALKGVSTSNLSDGILVIHVSPEDSKQKGDAVLQ 955 R RQL+LT A +VE AK+KQ+I+Y+ L G+S S+LSD + V+HV D+KQKGD VLQ Sbjct: 901 RSRQLLLTPNAVVIVEDAKVKQRIDYANLTGISVSSLSDSLFVLHVQRADNKQKGDVVLQ 960 Query: 956 CGHVFEAVTKLVMLVKKENIVNVVQGSLQFFISPGKEGTIVFDTGLEEQVYKNKNGQLTV 1015 HV E +TK + + N +N+ QGS+ F PG++GTI F G E + K KNG L V Sbjct: 961 SDHVIETLTKTALSANRVNSININQGSITFAGGPGRDGTIDFTPGSELLITKAKNGHLAV 1020 Query: 1016 VSVRRKS 1022 V+ R S Sbjct: 1021 VAPRLNS 1027 >gi|44889481 myosin IB isoform 2 [Homo sapiens] Length = 1078 Score = 758 bits (1956), Expect = 0.0 Identities = 426/1008 (42%), Positives = 616/1008 (61%), Gaps = 55/1008 (5%) Query: 11 VGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQ 70 +GV D VLL+ E+ F++NL+KRF + IYTYIG++++SVNPY+ L IY+ ++E Y+ Sbjct: 15 IGVGDMVLLEPLNEET-FINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYR 73 Query: 71 GVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQ 130 NF+EL PH++A++D AYR + + + ILI+GESGAGKTEASK ++ Y A C Sbjct: 74 NRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGA 133 Query: 131 SLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKS 190 + +++LL SNPVLEAFGNA+T+RNDNSSRFGKYMDI+FDF+G P+GG I +YL+EKS Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193 Query: 191 RVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWK 250 RVV Q GERNFH+FYQLL+G EE L+ L LERD Y YLS AK + + D +++ Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDS-AKVNGVDDAANFR 252 Query: 251 TVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQ----GCATIPDTHEIKWIAKL 306 TV NA ++ F + + E++ ++A+VL LGNI F+ + + + I D +E+K I +L Sbjct: 253 TVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICEL 312 Query: 307 LGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSL 366 G+ SVL A + R +EAK E+V L + + YARDA+AK +Y R F+WLVN+IN S+ Sbjct: 313 TGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESI 372 Query: 367 VNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGI 426 + RK V+G+LDIYGFE+F+ N FEQF INYCNEKLQQ+ IE TLK EQ EY E I Sbjct: 373 KAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDI 432 Query: 427 EWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETR 486 EW I YFNN IICDL+E GI+++LDEEC+RPG TD +FLEKL + H HFE+R Sbjct: 433 EWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESR 492 Query: 487 --KLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRE 544 K + + FR+ HYAG+V Y +GF++KNNDLLYR L + + K+ + +++ Sbjct: 493 MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKS 552 Query: 545 CFLLAELE--NRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDFLI 602 F N +RPPT G+QFK S+++L++ L +K P+YIRCIKPND+K F++ L+ Sbjct: 553 LFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALV 612 Query: 603 RHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKYIG 662 HQI+YLGL+E++RVRRAG+A+R+ YE L+RYK LC TWPHW GP GVE L + Sbjct: 613 CHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELE 672 Query: 663 YKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQAAI 722 EEY G++KIFIR PRTLF ED + L IQ Y+ R ++ +++ I Sbjct: 673 IPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQI 732 Query: 723 KLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISR-------NKPLCPD----------- 764 + A +R +K Q+ K + +I+ +I+G+ +R ++ C + Sbjct: 733 VIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHG 792 Query: 765 ---NEEFIVFVRKN----------------YILNLRYHLPK-TVLDKSW-LRPPGILENA 803 E+ F R N Y L ++ +P + +DK+W RP L++ Sbjct: 793 TQVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKMPSLSPIDKNWPSRPYLFLDST 852 Query: 804 SDLLRKMCVRNLVQKYCRGITAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVNSRIDE 863 L+++ +KY T ++K + ++K+ SE+F+ +K Y S+ QPF + + E Sbjct: 853 HKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGAYL-E 911 Query: 864 GDINPKVLQL--ISHEKIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVE--LAKIKQKI 919 + NPK +L EKI V K +R K+ R +LT + + +IK ++ Sbjct: 912 INKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEV 971 Query: 920 EYSALKGVSTSNLSDGILVIHVSP-EDSKQKGDAVLQCGHVFEAVTKL 966 + VS S+ +DG +H+ ++ KGD + H+ E TKL Sbjct: 972 PLVDVTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEMATKL 1019 >gi|4885503 myosin IA [Homo sapiens] Length = 1043 Score = 716 bits (1848), Expect = 0.0 Identities = 401/984 (40%), Positives = 607/984 (61%), Gaps = 28/984 (2%) Query: 11 VGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQ 70 VGV+D VLL+ ES + NL+ R+ IYTYIG +++SVNPYQ+L IY + YQ Sbjct: 8 VGVEDLVLLEPLVEES-LLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQ 66 Query: 71 GVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQ 130 F+EL PH+YA+A+ AY+ + + ILI+GESG+GKTEASK ++ Y A C + Sbjct: 67 DYTFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGE 126 Query: 131 SLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKS 190 + +++LL SNPVLEAFGNA+T+RN+NSSRFGKYMDI+FDF+G P+GG I +YL+EKS Sbjct: 127 QVNSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKS 186 Query: 191 RVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWK 250 R+V Q +GERNFHIFYQLLAG +E+ L L LERD Y YL+ ++ + D + ++ Sbjct: 187 RLVKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNH-EVSRVDGMDDASSFR 245 Query: 251 TVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQG----CATIPDTHEIKWIAKL 306 V +A +VI F+E ++ + + + VL LGN+ ++ Q + I D ++ I ++ Sbjct: 246 AVQSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEM 305 Query: 307 LGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSL 366 +G++ + AL R +E E+V+ L + + YARDA+AK +Y R F W+VN+IN S+ Sbjct: 306 VGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINESI 365 Query: 367 VNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGI 426 +K V+G+LDIYGFE+ + N FEQF INYCNEKLQQ+ IE TLK EQ EY+ EGI Sbjct: 366 KVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKREGI 425 Query: 427 EWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETR 486 W + YF+N IIC L+E +GI+++LDEEC+RPG +D +FL KL + KH H+E++ Sbjct: 426 PWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKHGHYESK 485 Query: 487 KLAGPKGR--KRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRE 544 + + +G FR+ HYAG+VTY F++KNNDLL+R L + + K+++ +LR Sbjct: 486 VTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQHPLLRS 545 Query: 545 CFLLA--ELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDFLI 602 F + + +RPPT G QFK+S++ L++ L SK P+YIRCIKPN+ ++ +F L+ Sbjct: 546 LFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQFSSDLV 605 Query: 603 RHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKYIG 662 Q +YLGL+E++RVRRAG+A+R+ Y FL+RY+ L TWPHW+G EGVE+++ + Sbjct: 606 ATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVEKVLGELS 665 Query: 663 YKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQAAI 722 E GKTKIFIR P+TLF E+ QL IQ Y+ R Y R++ I Sbjct: 666 MSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQLMRKSQI 725 Query: 723 KLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIV----FVRKN--- 775 + + +RG + +K + K +V +I+ F++G+ +R E + F+ K+ Sbjct: 726 LISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNYRKYFRSEAALTLADFIYKSMVQ 785 Query: 776 -YILNLRYHLPKT-VLDKSW-LRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQ 832 ++L L+ +LP T VLDK+W P L A+ L+++ + +++ ++ ++ +++ Sbjct: 786 KFLLGLKNNLPSTNVLDKTWPAAPYKCLSTANQELQQLFYQWKCKRFRDQLSPKQVEILR 845 Query: 833 QKVVTSEIFRGRKDGYTESLNQPFVNSRID-EGDINPKVLQLISHEK--IQYGVPVIKYD 889 +K+ SE+F+G+K Y +S+ PF I +G NPK+ +L E+ + V K + Sbjct: 846 EKLCASELFKGKKASYPQSVPIPFCGDYIGLQG--NPKLQKLKGGEEGPVLMAEAVKKVN 903 Query: 890 RKGFKARQRQLILTQKAAYVVELAKIKQKIEYSA--LKGVSTSNLSDGILVIHVSPEDS- 946 R K R L+LT+ + + K + KI + GVS ++L DG+ +H+S S Sbjct: 904 RGNGKTSSRILLLTKGHVILTDTKKSQAKIVIGLDNVAGVSVTSLKDGLFSLHLSEMSSV 963 Query: 947 KQKGDAVLQCGHVFEAVTKLVMLV 970 KGD +L HV E +TK+ V Sbjct: 964 GSKGDFLLVSEHVIELLTKMYRAV 987 >gi|194328685 myosin IB isoform 1 [Homo sapiens] Length = 1136 Score = 709 bits (1830), Expect = 0.0 Identities = 366/755 (48%), Positives = 509/755 (67%), Gaps = 10/755 (1%) Query: 11 VGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQ 70 +GV D VLL+ E+ F++NL+KRF + IYTYIG++++SVNPY+ L IY+ ++E Y+ Sbjct: 15 IGVGDMVLLEPLNEET-FINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYR 73 Query: 71 GVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQ 130 NF+EL PH++A++D AYR + + + ILI+GESGAGKTEASK ++ Y A C Sbjct: 74 NRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGA 133 Query: 131 SLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKS 190 + +++LL SNPVLEAFGNA+T+RNDNSSRFGKYMDI+FDF+G P+GG I +YL+EKS Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193 Query: 191 RVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWK 250 RVV Q GERNFH+FYQLL+G EE L+ L LERD Y YLS AK + + D +++ Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSL-DSAKVNGVDDAANFR 252 Query: 251 TVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQ----GCATIPDTHEIKWIAKL 306 TV NA ++ F + + E++ ++A+VL LGNI F+ + + + I D +E+K I +L Sbjct: 253 TVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICEL 312 Query: 307 LGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSL 366 G+ SVL A + R +EAK E+V L + + YARDA+AK +Y R F+WLVN+IN S+ Sbjct: 313 TGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESI 372 Query: 367 VNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGI 426 + RK V+G+LDIYGFE+F+ N FEQF INYCNEKLQQ+ IE TLK EQ EY E I Sbjct: 373 KAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDI 432 Query: 427 EWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETR 486 EW I YFNN IICDL+E GI+++LDEEC+RPG TD +FLEKL + H HFE+R Sbjct: 433 EWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESR 492 Query: 487 --KLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRE 544 K + + FR+ HYAG+V Y +GF++KNNDLLYR L + + K+ + +++ Sbjct: 493 MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKS 552 Query: 545 CFLLAELE--NRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDFLI 602 F N +RPPT G+QFK S+++L++ L +K P+YIRCIKPND+K F++ L+ Sbjct: 553 LFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALV 612 Query: 603 RHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKYIG 662 HQI+YLGL+E++RVRRAG+A+R+ YE L+RYK LC TWPHW GP GVE L + Sbjct: 613 CHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELE 672 Query: 663 YKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQAAI 722 EEY G++KIFIR PRTLF ED + L IQ Y+ R ++ +++ I Sbjct: 673 IPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQI 732 Query: 723 KLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISR 757 + A +R +K Q+ K + +I+ +I+G+ +R Sbjct: 733 VIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKAR 767 Score = 78.6 bits (192), Expect = 3e-14 Identities = 74/284 (26%), Positives = 129/284 (45%), Gaps = 38/284 (13%) Query: 712 REYVKKRQAAIKLEAHWRGALARKAIQR------RKWAVRIIRKFIKGFISRNKPLCPDN 765 +E + + A + A+W G+ AR+ ++R RK AV +I + G R Sbjct: 803 KEEARNKHAIAVIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRR------- 855 Query: 766 EEFIVFVRKN----------------YILNLRYHLPK-TVLDKSW-LRPPGILENASDLL 807 E+ F R N Y L ++ +P + +DK+W RP L++ L Sbjct: 856 -EYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKEL 914 Query: 808 RKMCVRNLVQKYCRGITAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVNSRIDEGDIN 867 +++ +KY T ++K + ++K+ SE+F+ +K Y S+ QPF + + E + N Sbjct: 915 KRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGAYL-EINKN 973 Query: 868 PKVLQL--ISHEKIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVE--LAKIKQKIEYSA 923 PK +L EKI V K +R K+ R +LT + + +IK ++ Sbjct: 974 PKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVD 1033 Query: 924 LKGVSTSNLSDGILVIHVSP-EDSKQKGDAVLQCGHVFEAVTKL 966 + VS S+ +DG +H+ ++ KGD + H+ E TKL Sbjct: 1034 VTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEMATKL 1077 >gi|240120050 myosin IB isoform 1 [Homo sapiens] Length = 1136 Score = 709 bits (1830), Expect = 0.0 Identities = 366/755 (48%), Positives = 509/755 (67%), Gaps = 10/755 (1%) Query: 11 VGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQ 70 +GV D VLL+ E+ F++NL+KRF + IYTYIG++++SVNPY+ L IY+ ++E Y+ Sbjct: 15 IGVGDMVLLEPLNEET-FINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYR 73 Query: 71 GVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQ 130 NF+EL PH++A++D AYR + + + ILI+GESGAGKTEASK ++ Y A C Sbjct: 74 NRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGA 133 Query: 131 SLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKS 190 + +++LL SNPVLEAFGNA+T+RNDNSSRFGKYMDI+FDF+G P+GG I +YL+EKS Sbjct: 134 EVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKS 193 Query: 191 RVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWK 250 RVV Q GERNFH+FYQLL+G EE L+ L LERD Y YLS AK + + D +++ Sbjct: 194 RVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSL-DSAKVNGVDDAANFR 252 Query: 251 TVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQ----GCATIPDTHEIKWIAKL 306 TV NA ++ F + + E++ ++A+VL LGNI F+ + + + I D +E+K I +L Sbjct: 253 TVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICEL 312 Query: 307 LGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSL 366 G+ SVL A + R +EAK E+V L + + YARDA+AK +Y R F+WLVN+IN S+ Sbjct: 313 TGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESI 372 Query: 367 VNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGI 426 + RK V+G+LDIYGFE+F+ N FEQF INYCNEKLQQ+ IE TLK EQ EY E I Sbjct: 373 KAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDI 432 Query: 427 EWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETR 486 EW I YFNN IICDL+E GI+++LDEEC+RPG TD +FLEKL + H HFE+R Sbjct: 433 EWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESR 492 Query: 487 --KLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRE 544 K + + FR+ HYAG+V Y +GF++KNNDLLYR L + + K+ + +++ Sbjct: 493 MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKS 552 Query: 545 CFLLAELE--NRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDFLI 602 F N +RPPT G+QFK S+++L++ L +K P+YIRCIKPND+K F++ L+ Sbjct: 553 LFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALV 612 Query: 603 RHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKYIG 662 HQI+YLGL+E++RVRRAG+A+R+ YE L+RYK LC TWPHW GP GVE L + Sbjct: 613 CHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELE 672 Query: 663 YKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQAAI 722 EEY G++KIFIR PRTLF ED + L IQ Y+ R ++ +++ I Sbjct: 673 IPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQI 732 Query: 723 KLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISR 757 + A +R +K Q+ K + +I+ +I+G+ +R Sbjct: 733 VIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKAR 767 Score = 78.6 bits (192), Expect = 3e-14 Identities = 74/284 (26%), Positives = 129/284 (45%), Gaps = 38/284 (13%) Query: 712 REYVKKRQAAIKLEAHWRGALARKAIQR------RKWAVRIIRKFIKGFISRNKPLCPDN 765 +E + + A + A+W G+ AR+ ++R RK AV +I + G R Sbjct: 803 KEEARNKHAIAVIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRR------- 855 Query: 766 EEFIVFVRKN----------------YILNLRYHLPK-TVLDKSW-LRPPGILENASDLL 807 E+ F R N Y L ++ +P + +DK+W RP L++ L Sbjct: 856 -EYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKEL 914 Query: 808 RKMCVRNLVQKYCRGITAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVNSRIDEGDIN 867 +++ +KY T ++K + ++K+ SE+F+ +K Y S+ QPF + + E + N Sbjct: 915 KRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGAYL-EINKN 973 Query: 868 PKVLQL--ISHEKIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVE--LAKIKQKIEYSA 923 PK +L EKI V K +R K+ R +LT + + +IK ++ Sbjct: 974 PKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQIKSEVPLVD 1033 Query: 924 LKGVSTSNLSDGILVIHVSP-EDSKQKGDAVLQCGHVFEAVTKL 966 + VS S+ +DG +H+ ++ KGD + H+ E TKL Sbjct: 1034 VTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEMATKL 1077 >gi|51100974 myosin ID [Homo sapiens] Length = 1006 Score = 667 bits (1721), Expect = 0.0 Identities = 423/1048 (40%), Positives = 597/1048 (56%), Gaps = 107/1048 (10%) Query: 12 GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71 G DFVL+D S F+ NLR RF + IYT+IG ++VSVNPY+ L IY +E Y+G Sbjct: 10 GKADFVLMDT-VSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKG 68 Query: 72 VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131 +E PPH++AIAD AY+ M + I+ISGESGAGKTEASK I++Y A +Q Sbjct: 69 RELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQR 128 Query: 132 LQIAR--DRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEK 189 ++ R + LL SN VLEAFGNA+T RNDNSSRFGKYMDI FDF+G P+GGHI +YL+EK Sbjct: 129 AEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEK 188 Query: 190 SRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDW 249 SRV+ Q GER+FH FYQLL GG E+ L L L++ Y Y+ G K SSI+D ++ Sbjct: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAAEF 247 Query: 250 KTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEIKWIAKLLGV 309 + V++A VI F +++ ++ I+A++LHLGN+ F D I + + IA+LL Sbjct: 248 RVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGD-TPLIENGKVVSIIAELLST 306 Query: 310 HPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNK 369 ++ +AL +R + + + T + + Y RDA AKA+Y R F W+V +IN + K Sbjct: 307 KTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVK 366 Query: 370 DFT-----RKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEME 424 ++ + TVIG+LDIYGFE+FD N FEQFCINYCNEKLQQL I+ LK EQ EY+ E Sbjct: 367 NYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQRE 426 Query: 425 GIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFE 484 GI W+ I YFNN+II DLVE++HKGII+ILD+ C+ G TD FLE L K+GKHAHF Sbjct: 427 GIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHFS 486 Query: 485 TRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRE 544 +RKL +FR+ HYAG+V Y GF++KN D L++ K ++ S N +L+ Sbjct: 487 SRKLCASDKILEFD-RDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKN 545 Query: 545 CFLLAEL---ENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDFL 601 + +L E +RP T T FKNS+ +L++ L SKEP Y+RCIKPND+K P FDD Sbjct: 546 MWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDER 605 Query: 602 IRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPA--EGVERLIK 659 RHQ++YLGL+E++RVRRAGFA+R+ YE FL RYK + TWP+ H P+ E V++LI+ Sbjct: 606 CRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPN-HDLPSDKEAVKKLIE 664 Query: 660 YIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQ 719 G++ ++ GKTKIFIR PRTLF E+ + Q++ RI Sbjct: 665 RCGFQ-DDVAYGKTKIFIRTPRTLFTLEEL----RAQMLIRI------------------ 701 Query: 720 AAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIVFVRKNYILN 779 + L+ WRG LAR +R K A+ IIR + + + K+YI Sbjct: 702 -VLFLQKVWRGTLARMRYKRTKAALTIIRYYRR------------------YKVKSYIHE 742 Query: 780 L--RYHLPKTVLDKS----WLRPPGILENASDLLRKMCVRNLVQKYCRGITAERKAMMQQ 833 + R+H KT+ D W PP +L + L+ + R + + I A ++ Sbjct: 743 VARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRA 802 Query: 834 KVVTSEIFRGRKD--GYTESLNQPFVNSRID----EGDINPKVLQLISHEK---IQYGVP 884 KV E+ +G++ G + ++ S+ D G P +L +K + + Sbjct: 803 KVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCH 862 Query: 885 VIKYDRKGFKARQRQLILTQKAAYVVELAK---IKQKIEYSALKGVSTSNLSDGILVIHV 941 V K +R K R + +T + Y ++ K + + I L G+S SN D ++V H Sbjct: 863 VRKVNRFS-KVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHT 921 Query: 942 SPEDSKQKGDAVLQC---------GHVFEAVTKLVMLVKKE------NIVNVVQGSLQFF 986 +D+K ++ C + E V LV K E N+ N VQ SL Sbjct: 922 --KDNKD----LIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHLQVNVTNPVQCSLH-- 973 Query: 987 ISPGKEGTIVFDTGLEE---QVYKNKNG 1011 GK+ T+ +T L + KN++G Sbjct: 974 ---GKKCTVSVETRLNQPQPDFTKNRSG 998 >gi|239582755 myosin IG [Homo sapiens] Length = 1018 Score = 612 bits (1577), Expect = e-175 Identities = 384/969 (39%), Positives = 543/969 (56%), Gaps = 76/969 (7%) Query: 12 GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71 G DFVLLD T E F+ NL+ RF + IYTYIG +LVSVNPYQEL +Y + YQG Sbjct: 10 GKPDFVLLDQVTMED-FMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQG 68 Query: 72 VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131 +E PPH+YA+A+ AY+ M + I+ISGESGAGKTEASK I++Y A +Q Sbjct: 69 RELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQR 128 Query: 132 LQIAR--DRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEK 189 ++ R D LL S VLEAFGNART RN NSSRFGKYMDI FDF+G P+GGHI SYL+EK Sbjct: 129 AEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEK 188 Query: 190 SRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQG-------HCAKESS 242 SRV+ Q+ GERNFH FYQLL G E+++L L LER+P +Y + QG H A +S Sbjct: 189 SRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALDS- 247 Query: 243 ISDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCA-----TIPDT 297 D+ + V+ A VI F+ ++E++ I+A++LHLGNI F E ++G + + Sbjct: 248 --DEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVAEE 305 Query: 298 HEIKWIAKLLGVHPSVLLEALTHRKIEAKTEEVICP-LTLELSVYARDAMAKAVYGRTFT 356 + +A+L ++L +L R + + E+I T + YARDA AKAVY R F Sbjct: 306 ALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDACAKAVYQRLFE 365 Query: 357 WLVNKINSSLVNKDFT-----RKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIE 411 W+VN+INS + + + TVIG+LDIYGFEVF N FEQFCINYCNEKLQQL I+ Sbjct: 366 WVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQ 425 Query: 412 RTLKAEQAEYEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLE 471 LK EQ EYE EGI W+ ++YFNN I DLVE H+GI+++LDE C G TD FL+ Sbjct: 426 LILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSSAGTITDRIFLQ 485 Query: 472 KLEEKVGKHAHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLK 531 L+ H H+ +R+L G +FR+ HYAG+VTY +GF++KN D L++ K Sbjct: 486 TLDMHHRHHLHYTSRQLCPTDKTMEFG-RDFRIKHYAGDVTYSVEGFIDKNRDFLFQDFK 544 Query: 532 EVLCKSKNIILRECFLLAE---LENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKP 588 +L S + LR + + E +RP T GT FKNS+ +L+E L SKEP Y+RCIKP Sbjct: 545 RLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVRCIKP 604 Query: 589 NDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWP-HWH 647 N+ K K D+ RHQ+ YLGL+E++RVRRAGFA R+ Y FL RYK C TWP H Sbjct: 605 NEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWPNHLL 664 Query: 648 GPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKR 707 G V L++ G + + G +K+FIR PRTL E S+ +L+ I Sbjct: 665 GSDKAAVSALLEQHGLQGD-VAFGHSKLFIRSPRTLVTLEQ----SRARLIPII------ 713 Query: 708 CLGRREYVKKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEE 767 + L+ WRG LAR +R + I+R F + + + Sbjct: 714 -------------VLLLQKAWRGTLARWRCRRLRAIYTIMRWFRRHKVRAH--------- 751 Query: 768 FIVFVRKNYILNLRYHLPKTVLDKSWLRPPGILENASDLLRKMCVRNLVQKYCRGITAER 827 + +++ + P D W PP +L+ D + R ++ + I Sbjct: 752 -LAELQRRF--QAARQPPLYGRDLVWPLPPAVLQPFQDTCHALFCRWRARQLVKNIPPSD 808 Query: 828 KAMMQQKVVTSEIFRG-RKD-GYTESLNQPFVNSRIDEGDINPKVLQLIS--HEKIQYGV 883 ++ KV +G R+D G + + +++S D + Q + +K +G Sbjct: 809 MPQIKAKVAAMGALQGLRQDWGCRRAWARDYLSSATDNPTASSLFAQRLKTLQDKDGFGA 868 Query: 884 PV----IKYDRKGFKARQRQLILTQKAAYVVE---LAKIKQKIEYSALKGVSTSNLSDGI 936 + ++ + K R R L+LT + Y ++ ++ + + A+ G+S ++ D + Sbjct: 869 VLFSSHVRKVNRFHKIRNRALLLTDQHLYKLDPDRQYRVMRAVPLEAVTGLSVTSGGDQL 928 Query: 937 LVIHVSPED 945 +V+H +D Sbjct: 929 VVLHARGQD 937 >gi|27544941 myosin IF [Homo sapiens] Length = 1098 Score = 596 bits (1537), Expect = e-170 Identities = 316/720 (43%), Positives = 451/720 (62%), Gaps = 27/720 (3%) Query: 12 GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71 GV D VLL T E A NLRKRF ++ I+TYIG++L+SVNP++++ +T +++LYQG Sbjct: 18 GVDDMVLLPQIT-EDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQG 76 Query: 72 VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131 +E PPH+YA+ DN YR M + N ++ISGESGAGKT A+K I+ Y + + Sbjct: 77 AAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK 136 Query: 132 LQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSR 191 +Q +D +L SNP+LEAFGNA+T+RN+NSSRFGKY +IQF G P GG I ++L+EKSR Sbjct: 137 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSR 196 Query: 192 VVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWKT 251 VV QNE ERNFHI+YQLL G +E+ LGL P Y YL+Q + D++D+ Sbjct: 197 VVMQNENERNFHIYYQLLEGASQEQRQNLGL-MTPDYYYYLNQSDTYQVDGTDDRSDFGE 255 Query: 252 VSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEIKWIAKLLGVHP 311 +A VI + + + ++A +LHLGNI F ED A + + + A LLG+ Sbjct: 256 TLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDG-NYARVESVDLLAFPAYLLGIDS 314 Query: 312 SVLLEALTHRKIEA----KTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLV 367 L E LT RK+++ ++E + L +E + Y RDA+AK +Y R F +LV IN ++ Sbjct: 315 GRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQ 374 Query: 368 NKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIE 427 + IG+LDIYGFE+F KNGFEQFCIN+ NEKLQQ+ IE TLKAEQ EY EGI Sbjct: 375 KPQ--EEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIR 432 Query: 428 WEPIKYFNNKIICDLVEER--HKGIISILDEECI---RPGPATDLSFLEKLEEKVGKHAH 482 W PI+YFNNK++CDL+E + GI+S+LD+ C G D + L+KL+ VG H H Sbjct: 433 WTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEH 492 Query: 483 FETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIIL 542 F + F + HYAG+V+Y GF E+N D+L+ L E++ S+ L Sbjct: 493 FNSWSAG------------FVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAFL 540 Query: 543 RECF-LLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDFL 601 R F + + + RP T G++ K + L+ TL+ P YIRCIKPN+ K P +++ Sbjct: 541 RMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENR 600 Query: 602 IRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKYI 661 ++HQ++YLGL E++RVRRAGFAYRR++ FLQRY L P+TWP W G +GV+ L++ + Sbjct: 601 VKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAV 660 Query: 662 GYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQAA 721 +P++Y++G TK+F++ P +LF E+ E IQ ++R + R+Y + R+ A Sbjct: 661 NMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEA 720 Score = 55.1 bits (131), Expect = 3e-07 Identities = 43/145 (29%), Positives = 68/145 (46%), Gaps = 17/145 (11%) Query: 816 VQKYCRGITAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVNSRIDEGDINPKVLQLIS 875 +QK R A RK + + S I +K+ S+N+ FV + + P++ Q + Sbjct: 700 IQKAWRRHVAVRK-YEEMREEASNILLNKKERRRNSINRNFVGDYLGLEE-RPELRQFLG 757 Query: 876 -HEKIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVELAKIKQ-------------KIEY 921 E++ + V KYDR+ FK +R LILT K YV+ K+K+ K++ Sbjct: 758 KRERVDFADSVTKYDRR-FKPIKRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDI 816 Query: 922 SALKGVSTSNLSDGILVIHVSPEDS 946 AL+GVS S D ++ DS Sbjct: 817 QALRGVSLSTRQDDFFILQEDAADS 841 >gi|55956916 myosin IE [Homo sapiens] Length = 1108 Score = 582 bits (1499), Expect = e-166 Identities = 322/769 (41%), Positives = 477/769 (62%), Gaps = 41/769 (5%) Query: 12 GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71 GV D VLL T E++ V+NL+KR+ ++ I+TYIG++L+SVNP++++ + ++E+YQG Sbjct: 20 GVDDMVLLSKIT-ENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQG 78 Query: 72 VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131 +E PPH+YA+ADN YR M + N ++ISGESGAGKT A+K I+ Y + Sbjct: 79 AAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTK 138 Query: 132 LQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSR 191 +Q +D +L SNP+LEAFGNA+T+RN+NSSRFGKY +IQF G P GG I ++L+EKSR Sbjct: 139 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSR 198 Query: 192 VVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWKT 251 VV +N GER+FHIFYQL+ G E+ LG+ Y YLS K I D+ +++ Sbjct: 199 VVMRNPGERSFHIFYQLIEGASAEQKHSLGI-TSMDYYYYLSLSGSYKVDDIDDRREFQE 257 Query: 252 VSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEIKWIAKLLGVHP 311 +A +VI + + I+A +LHLGNI F+E A + + + A LLG++ Sbjct: 258 TLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVG-NYAAVESEEFLAFPAYLLGINQ 316 Query: 312 SVLLEALTHRKIEA----KTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLV 367 L E LT R++++ K+E + L +E + Y RDA+AKA++ R F +LV+ IN ++ Sbjct: 317 DRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAM- 375 Query: 368 NKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIE 427 KD IG+LDIYGFE+F KNGFEQFCIN+ NEKLQQ+ IE TLKAEQ EY EGI Sbjct: 376 EKDHEEYN-IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIR 434 Query: 428 WEPIKYFNNKIICDLVEER--HKGIISILDEECI---RPGPATDLSFLEKLEEKVGKHAH 482 W PI+YFNNKI+CDL+E + GI+SILD+ C G D + L+KL+ ++G H H Sbjct: 435 WTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEH 494 Query: 483 FETRKLAGPKGRKRIGWME-FRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNII 541 F + W + F + HYAG+V+Y GF E+N D+L+ L E++ S+ Sbjct: 495 FNS-------------WNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPF 541 Query: 542 LRECF-LLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDF 600 ++ F + + + RP T G++ K + L+ TL+ P YIRCIKPN+ K+P +++ Sbjct: 542 IKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEES 601 Query: 601 LIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKY 660 ++HQ++YLGL E++RVRRAG+AYRR ++ FLQRY L TWP W G +GV L++ Sbjct: 602 RVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLLQS 661 Query: 661 IGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQA 720 + ++++LG++K+FI+ P +LF E+ E IQ ++++ + R++YV+ R+ Sbjct: 662 VNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMREE 721 Query: 721 AIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFI 769 A L L K +RR I R FI +I + P+ ++F+ Sbjct: 722 ASDL-------LLNKKERRRN---SINRNFIGDYIGMEEH--PELQQFV 758 Score = 67.4 bits (163), Expect = 7e-11 Identities = 67/264 (25%), Positives = 117/264 (44%), Gaps = 25/264 (9%) Query: 705 YKRCLGRREYVKKR---QAAIKLEAHWRGALARKAIQRRKWAVR-IIRKFIKGFISRNKP 760 Y RC+ E K R ++ +K + + G ++R +A R I +KF++ + K Sbjct: 583 YIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKA 642 Query: 761 LCPD--NEEFIVFVRKNYILNLRYHLPKTVLDKSWLRPPGILENASDLLRKMC--VRNLV 816 P EE + +N+ + K +++ P L ++ + ++ Sbjct: 643 TWPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVI 702 Query: 817 QKYCRGITAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVNSRIDEGDINPKVLQLIS- 875 QK R A RK +Q + S++ +K+ S+N+ F+ I + +P++ Q + Sbjct: 703 QKSWRKFVA-RKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEE-HPELQQFVGK 760 Query: 876 HEKIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVELAKIKQ-------------KIEYS 922 EKI + V KYDR+ FK +R L+LT K Y++ K+KQ KIE Sbjct: 761 REKIDFADTVTKYDRR-FKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIE 819 Query: 923 ALKGVSTSNLSDGILVIHVSPEDS 946 + VS S + D I ++H DS Sbjct: 820 RILSVSLSTMQDDIFILHEQEYDS 843 >gi|154354979 myosin X [Homo sapiens] Length = 2058 Score = 474 bits (1219), Expect = e-133 Identities = 292/778 (37%), Positives = 445/778 (57%), Gaps = 52/778 (6%) Query: 4 ALTARDKVGVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQEL-GIYT 62 A+ ++ GV D L S NL +R+ N IYTYIG++L SVNPYQ + G+Y Sbjct: 56 AMHPTNEEGVDDMASLTELHGGSIMY-NLFQRYKRNQIYTYIGSILASVNPYQPIAGLYE 114 Query: 63 VSQMELYQGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYF 122 + ME Y + ELPPH++AIA+ YR + +N ILISGESGAGKTE++K IL++ Sbjct: 115 PATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFL 174 Query: 123 AVTCPMTQSLQIARDR------LLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGI 176 +V + L + +L S+P++EAFGNA+T+ N+NSSRFGK++ + +G Sbjct: 175 SVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGN 234 Query: 177 PVGGHIISYLIEKSRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGH 236 GG I+ YL+EK+RVV QN GERN+HIFY LLAG E E L P+ Y YL+Q Sbjct: 235 IQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLS-TPENYHYLNQSG 293 Query: 237 CAKESSISDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPD 296 C ++ +ISD+ ++ V A V+ F++ ++ + ++A +LHLGNI F G A + Sbjct: 294 CVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF--ITAGGAQVSF 351 Query: 297 THEIKWIAKLLGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFT 356 + A+LLG+ P+ L +ALT R + + EE++ PL ++ +V +RD++A A+Y F Sbjct: 352 KTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFE 411 Query: 357 WLVNKINSSLV-NKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLK 415 W++ KINS + N+DF IG+LDI+GFE F+ N FEQF INY NEKLQ+ + Sbjct: 412 WVIKKINSRIKGNEDFKS---IGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFS 468 Query: 416 AEQAEYEMEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEE 475 EQ EY EG+ WE I + +N DL+E++ G++++++EE P ATD + LEKL Sbjct: 469 LEQLEYSREGLVWEDIDWIDNGECLDLIEKK-LGLLALINEESHFP-QATDSTLLEKLHS 526 Query: 476 KVGKHAHFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLC 535 + + HF + R+ F + HYAGEV Y +G LEKN D L +L Sbjct: 527 QHANN-HFYV--------KPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLR 577 Query: 536 KSKNIILRECFLLAELEN---------RRRPPTVGTQFKNSLSSLLETLISKEPSYIRCI 586 +S+ + + F N + R PTV +QFK+SL SL+ TL S P ++RCI Sbjct: 578 ESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCI 637 Query: 587 KPNDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHW 646 KPN +K P +FD ++ +Q++Y G++E +R+R+AG+A RR ++ F +RYK L + Sbjct: 638 KPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNL---- 693 Query: 647 HGPPAE---GVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVAR--- 700 P + L++ E++LGKTK+F+R + E E + + V+ Sbjct: 694 -ALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLR-----ESLEQKLEKRREEEVSHAAM 747 Query: 701 -IQATYKRCLGRREYVKKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISR 757 I+A L R++Y K + ++ ++R L R+ K A + +K ++G I+R Sbjct: 748 VIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIAR 805 >gi|189083802 myosin VIIA isoform 2 [Homo sapiens] Length = 2175 Score = 473 bits (1217), Expect = e-133 Identities = 284/803 (35%), Positives = 441/803 (54%), Gaps = 72/803 (8%) Query: 12 GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71 GV+D + L +E+ + NL R+ ++LIYTY G++LV+VNPYQ L IY+ + Y Sbjct: 66 GVEDMIRLGDL-NEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTN 124 Query: 72 VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131 E+PPH++AIADN Y M + +ISGESGAGKTE++K IL++ A Sbjct: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW 184 Query: 132 LQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSR 191 ++ ++L + P+LEAFGNA+T+RNDNSSRFGKY+DI F+ +G G I YL+EKSR Sbjct: 185 IE---QQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSR 241 Query: 192 VVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWKT 251 V Q ERN+H+FY +L G E++ LGL + Y YL+ G+C D ++ Sbjct: 242 VCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASD-YNYLAMGNCITCEGRVDSQEYAN 300 Query: 252 VSNAFSVIDFTEADLENLFGIIASVLHLGNIGFE----EDDQGCATIPDTHEIKWIAKLL 307 + +A V+ FT+ + + ++A++LHLGN+ +E E+ C + + + A LL Sbjct: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVL-FSPSLATAASLL 359 Query: 308 GVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLV 367 V+P L+ LT R + + E V PL+ E ++ RDA K +YGR F W+V+KIN+++ Sbjct: 360 EVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIY 419 Query: 368 NKDF----TRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEM 423 + IGLLDI+GFE F N FEQ CIN+ NE LQQ + K EQ EY++ Sbjct: 420 KPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDL 479 Query: 424 EGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHF 483 E I+W I++ +N+ D++ + IIS++DEE P TD + L KL + +A++ Sbjct: 480 ESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLNSQHKLNANY 538 Query: 484 ETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILR 543 PK +F + H+AG V Y T+GFLEKN D L+ + +++ S+N ++ Sbjct: 539 -----IPPKNNHE---TQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIK 590 Query: 544 ECF---LLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDF 600 + F + E R+R PT+ +QFK SL L+ TL + +P ++RCIKPN+ K+P FD Sbjct: 591 QIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRH 650 Query: 601 LIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGV-ERLIK 659 L Q++Y G+ME +R+RRAG+ R + F++RY+ L P P + G +R+ + Sbjct: 651 LCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAE 710 Query: 660 YIGYKPEEYKLGKTKIFIR---------------------FPRTLFATEDAFEFSKHQLV 698 + +++++GKTKIF++ + + +D F K + Sbjct: 711 AVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNA 770 Query: 699 A------------------------RIQATYKRCLGRREYVKKRQAAIKLEAHWRGALAR 734 A R+QA ++ ++Y RQ I+ +A R L R Sbjct: 771 ATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVR 830 Query: 735 KAIQRRKWAVRIIRKFIKGFISR 757 KA + R WAV ++ + +G I+R Sbjct: 831 KAFRHRLWAVLTVQAYARGMIAR 853 >gi|189083800 myosin VIIA isoform 3 [Homo sapiens] Length = 1204 Score = 473 bits (1217), Expect = e-133 Identities = 284/803 (35%), Positives = 441/803 (54%), Gaps = 72/803 (8%) Query: 12 GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71 GV+D + L +E+ + NL R+ ++LIYTY G++LV+VNPYQ L IY+ + Y Sbjct: 66 GVEDMIRLGDL-NEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTN 124 Query: 72 VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131 E+PPH++AIADN Y M + +ISGESGAGKTE++K IL++ A Sbjct: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW 184 Query: 132 LQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSR 191 ++ ++L + P+LEAFGNA+T+RNDNSSRFGKY+DI F+ +G G I YL+EKSR Sbjct: 185 IE---QQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSR 241 Query: 192 VVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWKT 251 V Q ERN+H+FY +L G E++ LGL + Y YL+ G+C D ++ Sbjct: 242 VCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASD-YNYLAMGNCITCEGRVDSQEYAN 300 Query: 252 VSNAFSVIDFTEADLENLFGIIASVLHLGNIGFE----EDDQGCATIPDTHEIKWIAKLL 307 + +A V+ FT+ + + ++A++LHLGN+ +E E+ C + + + A LL Sbjct: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVL-FSPSLATAASLL 359 Query: 308 GVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLV 367 V+P L+ LT R + + E V PL+ E ++ RDA K +YGR F W+V+KIN+++ Sbjct: 360 EVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIY 419 Query: 368 NKDF----TRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEM 423 + IGLLDI+GFE F N FEQ CIN+ NE LQQ + K EQ EY++ Sbjct: 420 KPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDL 479 Query: 424 EGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHF 483 E I+W I++ +N+ D++ + IIS++DEE P TD + L KL + +A++ Sbjct: 480 ESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLNSQHKLNANY 538 Query: 484 ETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILR 543 PK +F + H+AG V Y T+GFLEKN D L+ + +++ S+N ++ Sbjct: 539 -----IPPKNNHE---TQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIK 590 Query: 544 ECF---LLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDF 600 + F + E R+R PT+ +QFK SL L+ TL + +P ++RCIKPN+ K+P FD Sbjct: 591 QIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRH 650 Query: 601 LIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGV-ERLIK 659 L Q++Y G+ME +R+RRAG+ R + F++RY+ L P P + G +R+ + Sbjct: 651 LCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAE 710 Query: 660 YIGYKPEEYKLGKTKIFIR---------------------FPRTLFATEDAFEFSKHQLV 698 + +++++GKTKIF++ + + +D F K + Sbjct: 711 AVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNA 770 Query: 699 A------------------------RIQATYKRCLGRREYVKKRQAAIKLEAHWRGALAR 734 A R+QA ++ ++Y RQ I+ +A R L R Sbjct: 771 ATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVR 830 Query: 735 KAIQRRKWAVRIIRKFIKGFISR 757 KA + R WAV ++ + +G I+R Sbjct: 831 KAFRHRLWAVLTVQAYARGMIAR 853 >gi|189083798 myosin VIIA isoform 1 [Homo sapiens] Length = 2215 Score = 473 bits (1217), Expect = e-133 Identities = 284/803 (35%), Positives = 441/803 (54%), Gaps = 72/803 (8%) Query: 12 GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71 GV+D + L +E+ + NL R+ ++LIYTY G++LV+VNPYQ L IY+ + Y Sbjct: 66 GVEDMIRLGDL-NEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTN 124 Query: 72 VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131 E+PPH++AIADN Y M + +ISGESGAGKTE++K IL++ A Sbjct: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW 184 Query: 132 LQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSR 191 ++ ++L + P+LEAFGNA+T+RNDNSSRFGKY+DI F+ +G G I YL+EKSR Sbjct: 185 IE---QQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSR 241 Query: 192 VVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWKT 251 V Q ERN+H+FY +L G E++ LGL + Y YL+ G+C D ++ Sbjct: 242 VCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASD-YNYLAMGNCITCEGRVDSQEYAN 300 Query: 252 VSNAFSVIDFTEADLENLFGIIASVLHLGNIGFE----EDDQGCATIPDTHEIKWIAKLL 307 + +A V+ FT+ + + ++A++LHLGN+ +E E+ C + + + A LL Sbjct: 301 IRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVL-FSPSLATAASLL 359 Query: 308 GVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLV 367 V+P L+ LT R + + E V PL+ E ++ RDA K +YGR F W+V+KIN+++ Sbjct: 360 EVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIY 419 Query: 368 NKDF----TRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEM 423 + IGLLDI+GFE F N FEQ CIN+ NE LQQ + K EQ EY++ Sbjct: 420 KPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDL 479 Query: 424 EGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHF 483 E I+W I++ +N+ D++ + IIS++DEE P TD + L KL + +A++ Sbjct: 480 ESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFP-KGTDTTMLHKLNSQHKLNANY 538 Query: 484 ETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILR 543 PK +F + H+AG V Y T+GFLEKN D L+ + +++ S+N ++ Sbjct: 539 -----IPPKNNHE---TQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIK 590 Query: 544 ECF---LLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDF 600 + F + E R+R PT+ +QFK SL L+ TL + +P ++RCIKPN+ K+P FD Sbjct: 591 QIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRH 650 Query: 601 LIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGV-ERLIK 659 L Q++Y G+ME +R+RRAG+ R + F++RY+ L P P + G +R+ + Sbjct: 651 LCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAE 710 Query: 660 YIGYKPEEYKLGKTKIFIR---------------------FPRTLFATEDAFEFSKHQLV 698 + +++++GKTKIF++ + + +D F K + Sbjct: 711 AVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNA 770 Query: 699 A------------------------RIQATYKRCLGRREYVKKRQAAIKLEAHWRGALAR 734 A R+QA ++ ++Y RQ I+ +A R L R Sbjct: 771 ATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVR 830 Query: 735 KAIQRRKWAVRIIRKFIKGFISR 757 KA + R WAV ++ + +G I+R Sbjct: 831 KAFRHRLWAVLTVQAYARGMIAR 853 >gi|122937512 myosin VIIB [Homo sapiens] Length = 2116 Score = 467 bits (1202), Expect = e-131 Identities = 280/760 (36%), Positives = 422/760 (55%), Gaps = 57/760 (7%) Query: 12 GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71 GV D + L +E+ V NL R+ ++ IYTY G++LV+VNP+Q L +YT+ Q++LY Sbjct: 66 GVDDMIRLGDL-NEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYS 124 Query: 72 VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131 + ELPPHV+AIA+N Y M + +ISGESGAGKTE +K IL++ A Sbjct: 125 RHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSW 184 Query: 132 LQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSR 191 ++ ++L +NP+LEAFGNA+T+RNDNSSRFGKY+DI F+ G+ G I +L+EKSR Sbjct: 185 IE---QQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSR 241 Query: 192 VVYQNEGERNFHIFYQLLAG--GEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDW 249 V Q ERN+HIFY +L G E+++L LG P Y YL+ G+C ++D D+ Sbjct: 242 VCRQAPEERNYHIFYCMLMGVSAEDKQLLSLG---TPSEYHYLTMGNCTSCEGLNDAKDY 298 Query: 250 KTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEE---DDQGCATIPDTHEIKWIAKL 306 + +A ++ F++++ ++ ++A++LHLGN+GF ++ + + +T + KL Sbjct: 299 AHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKL 358 Query: 307 LGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSL 366 L V L + L I + E V L + + RDA K +YG F W+V KIN+++ Sbjct: 359 LEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAI 418 Query: 367 ----VNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYE 422 + IGLLDI+GFE F+ N FEQ CIN+ NE LQQ ++ EQ EY Sbjct: 419 FTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYR 478 Query: 423 MEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAH 482 E I W+ I Y +N+ DL+ + IIS+LDEE P TDL+ L+KL H Sbjct: 479 SENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFP-QGTDLTMLQKLNS-----VH 532 Query: 483 FETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIIL 542 + P K I F + H+AGEV Y +GFLEKN D+L + ++ SKN L Sbjct: 533 ANNKAFLQP---KNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFL 589 Query: 543 RECF----------------------LLAELENRRRPPTVGTQFKNSLSSLLETLISKEP 580 RE F L ++ +RP T+G+QFK SL L++ L + +P Sbjct: 590 REIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQP 649 Query: 581 SYIRCIKPNDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCP 640 +IRCIKPN+ K+P FD L Q++Y G+ME + +R++GF R +E F QR+ L P Sbjct: 650 YFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLP 709 Query: 641 DTW-PHWHGPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVA 699 + G + + +++K GKTKIF+R + + E + Q++ Sbjct: 710 NAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQ-----DTLLEVQRSQVLD 764 Query: 700 RIQATYKRCLG----RREYVKKRQAAIKLEAHWRGALARK 735 R + ++ L R+E++++R+AA+ L+A WRG R+ Sbjct: 765 RAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRR 804 Score = 34.7 bits (78), Expect = 0.47 Identities = 17/46 (36%), Positives = 28/46 (60%) Query: 696 QLVARIQATYKRCLGRREYVKKRQAAIKLEAHWRGALARKAIQRRK 741 Q ++QA + L R++ KR+A + ++AH RG AR+ Q+RK Sbjct: 834 QRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRK 879 >gi|118402590 myosin XV [Homo sapiens] Length = 3530 Score = 460 bits (1183), Expect = e-129 Identities = 280/774 (36%), Positives = 440/774 (56%), Gaps = 51/774 (6%) Query: 12 GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71 GV+D L+ E+ + NL+ RF NLIYTYIG++LVSVNPYQ GIY Q++ Y G Sbjct: 1223 GVEDMTQLEDL-QETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNG 1281 Query: 72 VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131 E PPH++A+A+ A+ M N I+ISGESG+GKTEA+K IL Y A M Q Sbjct: 1282 RALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAA---MNQK 1338 Query: 132 LQIARD-RLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKS 190 ++ + ++L + P+LE+FGNA+T+RNDNSSRFGK+++I F G+ G YL+EKS Sbjct: 1339 REVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKS 1397 Query: 191 RVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWK 250 R+V+Q + ERN+HIFY+LLAG + L+ + + Y YL+QG + + SD +D++ Sbjct: 1398 RIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQ-EAETYYYLNQGGNCEIAGKSDADDFR 1456 Query: 251 TVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEE---DDQGCATIPDTHEIKWIAKLL 307 + A V+ F+ D +++F I+AS+LHLGN+ FE+ D Q A++ EI+ +A+LL Sbjct: 1457 RLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELL 1516 Query: 308 GVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLV 367 + P L +A+T + E E++ PLT+E +V ARDA+AK +Y F+WL+ ++N+ + Sbjct: 1517 QISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVS 1576 Query: 368 NKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIE 427 + T I +LDIYGFE N FEQ CINY NE LQ L + + EQ EY E I+ Sbjct: 1577 PRQDTLS--IAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQID 1634 Query: 428 WEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETRK 487 W+ I + +N+ +L+ + GI+ ILD++C P ATD +FL+K G + + K Sbjct: 1635 WQEITFADNQPCINLISLKPYGILRILDDQCCFP-QATDHTFLQKCHYHHGANPLYSKPK 1693 Query: 488 LAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECF- 546 + P EF + HYAG+VTY FL+KN+D + + + ++ +S+ ++ F Sbjct: 1694 MPLP---------EFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFS 1744 Query: 547 ------------LLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEP 594 + + + TV +F+ SL L+E + P ++RC+KPN +KEP Sbjct: 1745 SHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEP 1804 Query: 595 SKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEG- 653 F+ ++ Q++Y G++E +R+R+ GF R ++ F+ RY L H PA G Sbjct: 1805 GLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALK----HDLPANGD 1860 Query: 654 --VERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLG- 710 V L + P Y++G +K+F++ L+ E + ++ T +RCL Sbjct: 1861 MCVSVLSRLCKVMPNMYRVGVSKLFLK--EHLY---QLLESMREHVLNLAALTLQRCLRG 1915 Query: 711 ---RREYVKKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPL 761 +R + R I L++ RG LAR+ Q+ + ++ R + ++SR + L Sbjct: 1916 FFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYL 1969 >gi|215982794 myosin VA isoform 2 [Homo sapiens] Length = 1828 Score = 457 bits (1176), Expect = e-128 Identities = 290/785 (36%), Positives = 427/785 (54%), Gaps = 56/785 (7%) Query: 11 VGVQDFVLLDAYTSESAFVDNLRKRFSEN-LIYTYIGTLLVSVNPYQELGIYTVSQMELY 69 VG D L +Y E A + NLR RF ++ LIYTY G +LV++NPY++L IY + Y Sbjct: 69 VGENDLTAL-SYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAY 127 Query: 70 QGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMT 129 G N ++ PH++A+A+ AY+ M + N I++SGESGAGKT ++K + YFA Sbjct: 128 SGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA 187 Query: 130 QSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEK 189 + +++L SNP++E+ GNA+T RNDNSSRFGKY++I FD + +G ++ +YL+EK Sbjct: 188 SEANV-EEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEK 246 Query: 190 SRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDW 249 SRVV+Q E ERN+HIFYQL A + L L + + Y QG + D + Sbjct: 247 SRVVFQAEEERNYHIFYQLCASAKLPEFKMLRL-GNADNFNYTKQGGSPVIEGVDDAKEM 305 Query: 250 KTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEIKWI-AKLLG 308 A +++ +E+ +F I+A +LHLGN+GF D TIP HE I L+G Sbjct: 306 AHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLMG 365 Query: 309 VHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVN 368 V + L HRK+ TE I P++ + ARDA+AK +Y + F W+V+ +N +L + Sbjct: 366 VDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQAL-H 424 Query: 369 KDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIEW 428 + + IG+LDIYGFE F+ N FEQFCINY NEKLQQ K EQ EY E I W Sbjct: 425 SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPW 484 Query: 429 EPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKL-EEKVGKHAHFETRK 487 I +++N+ +L+E + GI+ +LDEEC P TD ++ +KL + K A FE Sbjct: 485 TLIDFYDNQPCINLIESK-LGILDLLDEECKMP-KGTDDTWAQKLYNTHLNKCALFE--- 539 Query: 488 LAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECFL 547 + R+ F + H+A +V Y +GFLEKN D ++ +VL SK +L E F Sbjct: 540 ------KPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQ 593 Query: 548 --------LAELENRRRP---------------------PTVGTQFKNSLSSLLETLISK 578 + + R P TVG QF+NSL L+ETL + Sbjct: 594 DDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNAT 653 Query: 579 EPSYIRCIKPNDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSL 638 P Y+RCIKPND K P FD+ Q++ G++E +R+ AGF R Y+ F RY+ L Sbjct: 654 TPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVL 713 Query: 639 C--PDTWPHWHGPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQ 696 D +E+LI ++Y+ GKTKIF R + + + + + Sbjct: 714 MKQKDVLSDRKQTCKNVLEKLI----LDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAA 769 Query: 697 LVARIQATYKRCLGRREYVKKRQAAIKLEAHWRGALAR--KAIQRRKWAVRIIRKFIKGF 754 + RIQ T + L R++Y++ R+AAI ++ + RG AR RR A II+K+ + + Sbjct: 770 CI-RIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMY 828 Query: 755 ISRNK 759 + R + Sbjct: 829 VVRRR 833 >gi|215982791 myosin VA isoform 1 [Homo sapiens] Length = 1855 Score = 457 bits (1176), Expect = e-128 Identities = 290/785 (36%), Positives = 427/785 (54%), Gaps = 56/785 (7%) Query: 11 VGVQDFVLLDAYTSESAFVDNLRKRFSEN-LIYTYIGTLLVSVNPYQELGIYTVSQMELY 69 VG D L +Y E A + NLR RF ++ LIYTY G +LV++NPY++L IY + Y Sbjct: 69 VGENDLTAL-SYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAY 127 Query: 70 QGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMT 129 G N ++ PH++A+A+ AY+ M + N I++SGESGAGKT ++K + YFA Sbjct: 128 SGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA 187 Query: 130 QSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEK 189 + +++L SNP++E+ GNA+T RNDNSSRFGKY++I FD + +G ++ +YL+EK Sbjct: 188 SEANV-EEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEK 246 Query: 190 SRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDW 249 SRVV+Q E ERN+HIFYQL A + L L + + Y QG + D + Sbjct: 247 SRVVFQAEEERNYHIFYQLCASAKLPEFKMLRL-GNADNFNYTKQGGSPVIEGVDDAKEM 305 Query: 250 KTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEIKWI-AKLLG 308 A +++ +E+ +F I+A +LHLGN+GF D TIP HE I L+G Sbjct: 306 AHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLMG 365 Query: 309 VHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVN 368 V + L HRK+ TE I P++ + ARDA+AK +Y + F W+V+ +N +L + Sbjct: 366 VDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQAL-H 424 Query: 369 KDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIEW 428 + + IG+LDIYGFE F+ N FEQFCINY NEKLQQ K EQ EY E I W Sbjct: 425 SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPW 484 Query: 429 EPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKL-EEKVGKHAHFETRK 487 I +++N+ +L+E + GI+ +LDEEC P TD ++ +KL + K A FE Sbjct: 485 TLIDFYDNQPCINLIESK-LGILDLLDEECKMP-KGTDDTWAQKLYNTHLNKCALFE--- 539 Query: 488 LAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECFL 547 + R+ F + H+A +V Y +GFLEKN D ++ +VL SK +L E F Sbjct: 540 ------KPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQ 593 Query: 548 --------LAELENRRRP---------------------PTVGTQFKNSLSSLLETLISK 578 + + R P TVG QF+NSL L+ETL + Sbjct: 594 DDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNAT 653 Query: 579 EPSYIRCIKPNDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSL 638 P Y+RCIKPND K P FD+ Q++ G++E +R+ AGF R Y+ F RY+ L Sbjct: 654 TPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVL 713 Query: 639 C--PDTWPHWHGPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQ 696 D +E+LI ++Y+ GKTKIF R + + + + + Sbjct: 714 MKQKDVLSDRKQTCKNVLEKLI----LDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAA 769 Query: 697 LVARIQATYKRCLGRREYVKKRQAAIKLEAHWRGALAR--KAIQRRKWAVRIIRKFIKGF 754 + RIQ T + L R++Y++ R+AAI ++ + RG AR RR A II+K+ + + Sbjct: 770 CI-RIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMY 828 Query: 755 ISRNK 759 + R + Sbjct: 829 VVRRR 833 >gi|153945715 myosin VC [Homo sapiens] Length = 1742 Score = 457 bits (1176), Expect = e-128 Identities = 282/779 (36%), Positives = 437/779 (56%), Gaps = 51/779 (6%) Query: 11 VGVQDFVLLDAYTSESAFVDNLRKRFSEN-LIYTYIGTLLVSVNPYQELGIYTVSQMELY 69 VG D L +Y E A + NLR RF+E+ LIYTY G +LV++NPY++L IY + + Y Sbjct: 67 VGENDLTAL-SYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAY 125 Query: 70 QGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMT 129 G N ++ PH++A+A+ AY+ M N I++SGESGAGKT +++ + YFA Sbjct: 126 SGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSG 185 Query: 130 QSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEK 189 + + D++L SNP+ EA GNA+T RNDNSSRFGKY +I FD Q +G ++ +YL+EK Sbjct: 186 SNAHV-EDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEK 244 Query: 190 SRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDW 249 SRVV+Q+E ERN+HIFYQL A ++ +L L + + Y G ++D+ + Sbjct: 245 SRVVFQSENERNYHIFYQLCASAQQSEFKHLKL-GSAEEFNYTRMGGNTVIEGVNDRAEM 303 Query: 250 KTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEE--DDQGCATIPDTHEIKWIAKLL 307 F+++ F E ++F I+A++LHLGN+ +++ + D+H +K +LL Sbjct: 304 VETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSH-LKVFCELL 362 Query: 308 GVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLV 367 G+ + + L +RKI +E V+ P+T +V ARDA+AK +Y F ++V +IN +L Sbjct: 363 GLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQAL- 421 Query: 368 NKDFTRK--TVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEG 425 F+ K T IG+LDIYGFE FD N FEQFCINY NEKLQQ K EQ EY E Sbjct: 422 --QFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKED 479 Query: 426 IEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEK-VGKHAHFE 484 I W I +++N+ + DL+E + GI+ +LDEEC+ P TD ++L+KL V ++ FE Sbjct: 480 IPWTLIDFYDNQPVIDLIEAK-MGILELLDEECLLP-HGTDENWLQKLYNNFVNRNPLFE 537 Query: 485 TRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSK------ 538 + R+ F + H+A +V Y +GFLEKN D +Y L E+L SK Sbjct: 538 ---------KPRMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCAN 588 Query: 539 --------------NIILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIR 584 I ++ + + ++ TVG++F++SL L+ETL + P Y+R Sbjct: 589 FFQENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVR 648 Query: 585 CIKPNDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWP 644 CIKPND K P +FD I Q++ G++E +R+ + R Y F RY L Sbjct: 649 CIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQEL 708 Query: 645 HWHGPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQAT 704 + E + ++ + +Y+ GKTKIF R + + + + Q +Q Sbjct: 709 SF-SDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLD-KLRQSCVMVQKH 766 Query: 705 YKRCLGRREYVKKRQAAIKLEAHWRG-ALARKAIQ----RRKWAVRIIRKFIKGFISRN 758 + L R++++++R+AA+ ++ ++RG RKAI + WA II+K +G++ R+ Sbjct: 767 MRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRS 825 >gi|122937345 myosin VB [Homo sapiens] Length = 1848 Score = 451 bits (1161), Expect = e-126 Identities = 319/979 (32%), Positives = 478/979 (48%), Gaps = 128/979 (13%) Query: 11 VGVQDFVLLDAYTSESAFVDNLRKRFSE-NLIYTYIGTLLVSVNPYQELGIYTVSQMELY 69 VG D L +Y E A + NL+ RF E N IYTY G +LV++NPY++L IY + Y Sbjct: 69 VGENDLTAL-SYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTY 127 Query: 70 QGVNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMT 129 G N ++ PH++A+A+ AY+ M + N I++SGESGAGKT ++K + YFA Sbjct: 128 SGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSA 187 Query: 130 QSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEK 189 I +++L S+P++EA GNA+T RNDNSSRFGKY+ I FD + +G ++ +YL+EK Sbjct: 188 SETNI-EEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEK 246 Query: 190 SRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDW 249 SRVV+Q + ERN+HIFYQL A L L + Y SQG + D D+ Sbjct: 247 SRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFF-YTSQGGDTSIEGVDDAEDF 305 Query: 250 KTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGF--EEDDQGCATIPDTHEIKWIAKLL 307 + AF+++ E+ ++F IIAS+LHLG++ E D C+ P + +LL Sbjct: 306 EKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLL 365 Query: 308 GVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLV 367 GV S + L HRK+ +E + ++L+ + AR+A+AK +Y + F W+V IN +L Sbjct: 366 GVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKAL- 424 Query: 368 NKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIE 427 + + + IG+LDIYGFE F+ N FEQFCINY NEKLQQ K EQ EY E I Sbjct: 425 HTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIP 484 Query: 428 WEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETRK 487 W I +++N+ DL+E + GI+ +LDEEC P TD ++ +KL ++ HF+ Sbjct: 485 WTLIDFYDNQPCIDLIEAK-LGILDLLDEECKVP-KGTDQNWAQKLYDRHSSSQHFQ--- 539 Query: 488 LAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSK--------- 538 + R+ F ++H+A +V Y + GFLEKN D +Y +L SK Sbjct: 540 ------KPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFH 593 Query: 539 -----------------NIILRECFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPS 581 I +R ++ N+ TVG QF+ SL L+ETL + P Sbjct: 594 DDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPH 653 Query: 582 YIRCIKPNDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPD 641 Y+RCIKPND K P FD Q++ G++E +R+ AG+ R Y F RY+ L Sbjct: 654 YVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKK 713 Query: 642 TWPHWHGPPA---EGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATE---DAF----- 690 A +E LIK P++++ G+TKIF R + + + D F Sbjct: 714 RELANTDKKAICRSVLENLIK----DPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATI 769 Query: 691 -----------EFSKHQLVARIQATYKRCLGR-----REYVKKRQAAIKLEAHWRGALAR 734 + H+L + C G E++++ +AA+ L+ H+R AR Sbjct: 770 MIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRAR 829 Query: 735 KAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFIVFVRKNYILNLRYHLPKTVLDKSWL 794 +A QR + A +I+ F + +FVR+ Y L H T Sbjct: 830 QAYQRVRRAAVVIQAFTRA----------------MFVRRTYRQVLMEHKATT------- 866 Query: 795 RPPGILENASDLLRKMCVRNLVQKYCRGITAER--KAMMQQKVVTSEIFRGRKDGYTESL 852 +QK+ RG A R + + +V FR K L Sbjct: 867 ---------------------IQKHVRGWMARRHFQRLRDAAIVIQCAFRMLK--ARREL 903 Query: 853 NQPFVNSRIDEGDINPKVLQLISHEKIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVEL 912 + +R E + K L + K+ I K FK QL +T + Y +E+ Sbjct: 904 KALRIEARSAE---HLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVT-TSTYTMEV 959 Query: 913 AKIKQK-IEYSALKGVSTS 930 ++K++ + Y G TS Sbjct: 960 ERLKKELVHYQQSPGEDTS 978 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 444 bits (1143), Expect = e-124 Identities = 281/782 (35%), Positives = 427/782 (54%), Gaps = 38/782 (4%) Query: 13 VQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQGV 72 ++D +L + E A + NL+ R+ +IYTY G V+VNPY+ L +YT + Y+G Sbjct: 87 IEDMAML-TFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGK 145 Query: 73 NFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQSL 132 E PPH+++I+DNAY+ M + N ILI+GESGAGKT +K++++YFAV + Sbjct: 146 KRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRS 205 Query: 133 Q--------IARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIIS 184 + D+++ +NP LEAFGNA+T+RNDNSSRFGK++ I F G I + Sbjct: 206 KKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIET 265 Query: 185 YLIEKSRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSIS 244 YL+EKSRV++Q + ER++HIFYQ+L+ + E L L + +P Y ++SQG +SI Sbjct: 266 YLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGE-TTVASID 324 Query: 245 DKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPD-THEIKWI 303 D + NAF V+ FT + +++ + +++H GN+ F+ + PD T E Sbjct: 325 DAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKS 384 Query: 304 AKLLGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKIN 363 A L+G++ + LL+ L H +++ E V ++ +YA A+AKAVY R F W+V +IN Sbjct: 385 AYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRIN 444 Query: 364 SSLVNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEM 423 ++L K R+ IG+LDI GFE+FD N FEQ CIN+ NEKLQQ EQ EY+ Sbjct: 445 ATLETKQ-PRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 503 Query: 424 EGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKL-EEKVGKHAH 482 EGIEW I + + C + E+ GI+SIL+EEC+ P ATD++F KL + +GK A+ Sbjct: 504 EGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFP-KATDMTFKAKLFDNHLGKSAN 562 Query: 483 FETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIIL 542 F+ P+ K F L+HYAG V Y G+L+KN D L + + KS +L Sbjct: 563 FQK-----PRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLL 617 Query: 543 RECFLL-----AELENRRRPPTVGTQF-------KNSLSSLLETLISKEPSYIRCIKPND 590 F A +E + G+ F + +L+ L+ L S P ++RCI PN+ Sbjct: 618 STLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNE 677 Query: 591 RKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHG-P 649 K P D+ L+ HQ++ G++E +R+ R GF R Y F QRY+ L P P Sbjct: 678 TKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFID 737 Query: 650 PAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCL 709 +G E+L+ + +YK G TK+F + L E+ + +++ RIQA + L Sbjct: 738 SRKGAEKLLSSLDIDHNQYKFGHTKVFFK-AGLLGLLEEMRDERLSRIITRIQAQSRGVL 796 Query: 710 GRREYVK---KRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNE 766 R EY K +R + + ++ + R + K K +I K + R K + E Sbjct: 797 ARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKI--KPLLKSAEREKEMASMKE 854 Query: 767 EF 768 EF Sbjct: 855 EF 856 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 434 bits (1115), Expect = e-121 Identities = 269/751 (35%), Positives = 417/751 (55%), Gaps = 45/751 (5%) Query: 24 SESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQGVNFFELPPHVYA 83 +E++ + NL+ R+ LIYTY G V +NPY+ L IY+ + +E+Y+G E+PPH+YA Sbjct: 97 NEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYA 156 Query: 84 IADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQSLQI------ARD 137 I+++AYR M + + IL +GESGAGKTE +KK+++Y A + + Sbjct: 157 ISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELER 216 Query: 138 RLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSRVVYQNE 197 +LL +NP+LE+FGNA+T++NDNSSRFGK++ I FD G VG +I +YL+EKSR V Q + Sbjct: 217 QLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAK 276 Query: 198 GERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWKTVSNAFS 257 ER FHIFYQLL+G E S L LE Y++LS G+ DK++++ A Sbjct: 277 DERTFHIFYQLLSGAGEHLKSDLLLEGFNN-YRFLSNGYIPIPGQ-QDKDNFQETMEAMH 334 Query: 258 VIDFTEADLENLFGIIASVLHLGNIGFEED---DQGCATIPDTHEIKWIAKLLGVHPSVL 314 ++ F+ ++ ++ +++SVL GNI F+++ DQ A++P+ + + LLG++ Sbjct: 335 IMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQ--ASMPENTVAQKLCHLLGMNVMEF 392 Query: 315 LEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNKDFTRK 374 A+ +I+ + V T E + +A +A+AKA Y R F WLV++IN +L Sbjct: 393 TRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGA 452 Query: 375 TVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIEWEPIKYF 434 + IG+LDI GFE+F+ N FEQ CINY NEKLQQL EQ EY+ EGIEW I + Sbjct: 453 SFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFG 512 Query: 435 NNKIIC-DLVEE--RHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETRKLAGP 491 + C DL+E G++++LDEEC P ATD +F+EKL ++ G H+ F+ Sbjct: 513 LDLQPCIDLIERPANPPGVLALLDEECWFP-KATDKTFVEKLVQEQGSHSKFQ------- 564 Query: 492 KGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRE------- 544 K R+ +F ++HYAG+V Y +L KN D L ++ +L +S + + E Sbjct: 565 KPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDR 624 Query: 545 -------------CFLLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDR 591 F A + TVG +K SL+ L+ TL + P+++RCI PN Sbjct: 625 IVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHE 684 Query: 592 KEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPA 651 K K D L+ Q++ G++E +R+ R GF R ++ F QRY+ L P+ P Sbjct: 685 KRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGK 744 Query: 652 EGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGR 711 + ER+I+ + P Y++G++KIF R L E+ + ++ QA + L R Sbjct: 745 QACERMIRALELDPNLYRIGQSKIFFR-AGVLAHLEEERDLKITDIIIFFQAVCRGYLAR 803 Query: 712 REYVKKRQAAIKLEAHWRGALARKAIQRRKW 742 + + KK+Q L+ R A ++ +W Sbjct: 804 KAFAKKQQQLSALKVLQRNCAAYLKLRHWQW 834 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 429 bits (1104), Expect = e-120 Identities = 265/749 (35%), Positives = 411/749 (54%), Gaps = 41/749 (5%) Query: 24 SESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQGVNFFELPPHVYA 83 +E++ + NLR+R+ LIYTY G V VNPY+ L IY+ +++Y+G E+PPH+YA Sbjct: 97 NEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYA 156 Query: 84 IADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPM------TQSLQIARD 137 IAD AYR M + + IL +GESGAGKTE +KK+++Y AV T Sbjct: 157 IADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEK 216 Query: 138 RLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSRVVYQNE 197 +LL +NP+LEAFGNA+T++NDNSSRFGK++ I FD G VG +I +YL+EKSR + Q Sbjct: 217 QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAR 276 Query: 198 GERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWKTVSNAFS 257 ER FHIFY ++AG +E+ S L LE Y +LS G ++ D+ +TV A + Sbjct: 277 DERTFHIFYYMIAGAKEKMRSDLLLEGFNN-YTFLSNGFVPIPAAQDDEMFQETV-EAMA 334 Query: 258 VIDFTEADLENLFGIIASVLHLGNIGF-EEDDQGCATIPDTHEIKWIAKLLGVHPSVLLE 316 ++ F+E + ++ +++SVL LGNI F +E + A++PD + + L+G++ + Sbjct: 335 IMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTR 394 Query: 317 ALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNKDFTRKTV 376 ++ +I+ + V T E + +A +A+AKA Y R F W++ ++N +L + Sbjct: 395 SILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASF 454 Query: 377 IGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIEWEPIKYFNN 436 +G+LDI GFE+F+ N FEQ CINY NEKLQQL EQ EY+ EGIEW I + + Sbjct: 455 LGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLD 514 Query: 437 KIIC-DLVEERHK--GIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETRKLAGPKG 493 C +L+E + G++++LDEEC P ATD SF+EKL + G H F+ K K Sbjct: 515 LQPCIELIERPNNPPGVLALLDEECWFP-KATDKSFVEKLCTEQGSHPKFQKPKQLKDK- 572 Query: 494 RKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECF------- 546 EF ++HYAG+V Y +L KN D L ++ +L S + + + + Sbjct: 573 ------TEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIV 626 Query: 547 ---LLAELENRRRPP----------TVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKE 593 +A++ P TVG +K L L+ TL + P+++RCI PN K Sbjct: 627 GLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKR 686 Query: 594 PSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEG 653 K D FL+ Q++ G++E +R+ R GF R ++ F QRY+ L + P + Sbjct: 687 SGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQA 746 Query: 654 VERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRRE 713 +IK + P Y++G++KIF R L E+ + ++ QA + L R+ Sbjct: 747 CILMIKALELDPNLYRIGQSKIFFR-TGVLAHLEEERDLKITDVIMAFQAMCRGYLARKA 805 Query: 714 YVKKRQAAIKLEAHWRGALARKAIQRRKW 742 + K++Q ++ R A ++ +W Sbjct: 806 FAKRQQQLTAMKVIQRNCAAYLKLRNWQW 834 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 429 bits (1104), Expect = e-120 Identities = 265/749 (35%), Positives = 411/749 (54%), Gaps = 41/749 (5%) Query: 24 SESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQGVNFFELPPHVYA 83 +E++ + NLR+R+ LIYTY G V VNPY+ L IY+ +++Y+G E+PPH+YA Sbjct: 97 NEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYA 156 Query: 84 IADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPM------TQSLQIARD 137 IAD AYR M + + IL +GESGAGKTE +KK+++Y AV T Sbjct: 157 IADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEK 216 Query: 138 RLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSRVVYQNE 197 +LL +NP+LEAFGNA+T++NDNSSRFGK++ I FD G VG +I +YL+EKSR + Q Sbjct: 217 QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQAR 276 Query: 198 GERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWKTVSNAFS 257 ER FHIFY ++AG +E+ S L LE Y +LS G ++ D+ +TV A + Sbjct: 277 DERTFHIFYYMIAGAKEKMRSDLLLEGFNN-YTFLSNGFVPIPAAQDDEMFQETV-EAMA 334 Query: 258 VIDFTEADLENLFGIIASVLHLGNIGF-EEDDQGCATIPDTHEIKWIAKLLGVHPSVLLE 316 ++ F+E + ++ +++SVL LGNI F +E + A++PD + + L+G++ + Sbjct: 335 IMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTR 394 Query: 317 ALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNKDFTRKTV 376 ++ +I+ + V T E + +A +A+AKA Y R F W++ ++N +L + Sbjct: 395 SILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASF 454 Query: 377 IGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIEWEPIKYFNN 436 +G+LDI GFE+F+ N FEQ CINY NEKLQQL EQ EY+ EGIEW I + + Sbjct: 455 LGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLD 514 Query: 437 KIIC-DLVEERHK--GIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETRKLAGPKG 493 C +L+E + G++++LDEEC P ATD SF+EKL + G H F+ K K Sbjct: 515 LQPCIELIERPNNPPGVLALLDEECWFP-KATDKSFVEKLCTEQGSHPKFQKPKQLKDK- 572 Query: 494 RKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECF------- 546 EF ++HYAG+V Y +L KN D L ++ +L S + + + + Sbjct: 573 ------TEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIV 626 Query: 547 ---LLAELENRRRPP----------TVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKE 593 +A++ P TVG +K L L+ TL + P+++RCI PN K Sbjct: 627 GLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKR 686 Query: 594 PSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEG 653 K D FL+ Q++ G++E +R+ R GF R ++ F QRY+ L + P + Sbjct: 687 SGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQA 746 Query: 654 VERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRRE 713 +IK + P Y++G++KIF R L E+ + ++ QA + L R+ Sbjct: 747 CILMIKALELDPNLYRIGQSKIFFR-TGVLAHLEEERDLKITDVIMAFQAMCRGYLARKA 805 Query: 714 YVKKRQAAIKLEAHWRGALARKAIQRRKW 742 + K++Q ++ R A ++ +W Sbjct: 806 FAKRQQQLTAMKVIQRNCAAYLKLRNWQW 834 >gi|156104908 myosin heavy chain 6 [Homo sapiens] Length = 1939 Score = 429 bits (1104), Expect = e-120 Identities = 266/751 (35%), Positives = 418/751 (55%), Gaps = 38/751 (5%) Query: 13 VQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQGV 72 ++D +L + E A + NL++R++ +IYTY G V+VNPY+ L +Y + Y+G Sbjct: 87 IEDMAML-TFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGK 145 Query: 73 NFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPM---- 128 E PPH+++I+DNAY+ M + N ILI+GESGAGKT +K++++YFA + Sbjct: 146 KRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRG 205 Query: 129 -----TQSLQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHII 183 + D+++ +NP LEAFGNA+T+RNDNSSRFGK++ I F G I Sbjct: 206 KKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 265 Query: 184 SYLIEKSRVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSI 243 +YL+EKSRV++Q + ERN+HIFYQ+L+ + E L L + +P Y ++SQG +SI Sbjct: 266 TYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGE-VSVASI 324 Query: 244 SDKNDWKTVSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPD-THEIKW 302 D + +AF V+ FT + ++ + +++H GN+ F++ + PD T + Sbjct: 325 DDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADK 384 Query: 303 IAKLLGVHPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKI 362 A L+G++ + LL+ L H +++ E V +++ Y+ A+AKAVY + F W+V +I Sbjct: 385 SAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRI 444 Query: 363 NSSLVNKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYE 422 N++L K R+ IG+LDI GFE+FD N FEQ CIN+ NEKLQQ EQ EY+ Sbjct: 445 NATLETKQ-PRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYK 503 Query: 423 MEGIEWEPIKYFNNKIICDLVEERHKGIISILDEECIRPGPATDLSFLEKL-EEKVGKHA 481 EGIEW I + + C + E+ GI+SIL+EEC+ P ATD++F KL + +GK Sbjct: 504 KEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFP-KATDMTFKAKLYDNHLGKSN 562 Query: 482 HFETRKLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNII 541 +F+ K KG++ F L+HYAG V Y G+LEKN D L + + KS + Sbjct: 563 NFQ--KPRNIKGKQE---AHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKL 617 Query: 542 LRECF---LLAELENRRRP----------PTVGTQFKNSLSSLLETLISKEPSYIRCIKP 588 + F A+ + + TV + +L+ L+ L + P ++RCI P Sbjct: 618 MATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIP 677 Query: 589 NDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHG 648 N+RK P D+ L+ HQ++ G++E +R+ R GF R Y F QRY+ L P P Sbjct: 678 NERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQF 737 Query: 649 -PPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKR 707 +G E+L+ + +YK G TK+F + L E+ + +++ R+QA + Sbjct: 738 IDSRKGTEKLLSSLDIDHNQYKFGHTKVFFK-AGLLGLLEEMRDERLSRIITRMQAQARG 796 Query: 708 CLGRREY---VKKRQAAIKLEAHWRGALARK 735 L R E+ V++R A + ++ + R + K Sbjct: 797 QLMRIEFKKIVERRDALLVIQWNIRAFMGVK 827 >gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo sapiens] Length = 1979 Score = 429 bits (1103), Expect = e-120 Identities = 267/756 (35%), Positives = 414/756 (54%), Gaps = 48/756 (6%) Query: 24 SESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQGVNFFELPPHVYA 83 +E++ + NLR+R+ LIYTY G V VNPY+ L IY+ +++Y+G E+PPH+YA Sbjct: 97 NEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYA 156 Query: 84 IADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTC---------PMTQSLQI 134 IAD AYR M + + IL +GESGAGKTE +KK+++Y AV +TQ Sbjct: 157 IADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSF 216 Query: 135 A----RDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKS 190 A +LL +NP+LEAFGNA+T++NDNSSRFGK++ I FD G VG +I +YL+EKS Sbjct: 217 AYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 276 Query: 191 RVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWK 250 R + Q ER FHIFY ++AG +E+ S L LE Y +LS G ++ D+ + Sbjct: 277 RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNN-YTFLSNGFVPIPAAQDDEMFQE 335 Query: 251 TVSNAFSVIDFTEADLENLFGIIASVLHLGNIGF-EEDDQGCATIPDTHEIKWIAKLLGV 309 TV A +++ F+E + ++ +++SVL LGNI F +E + A++PD + + L+G+ Sbjct: 336 TV-EAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 394 Query: 310 HPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNK 369 + + ++ +I+ + V T E + +A +A+AKA Y R F W++ ++N +L Sbjct: 395 NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKT 454 Query: 370 DFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIEWE 429 + +G+LDI GFE+F+ N FEQ CINY NEKLQQL EQ EY+ EGIEW Sbjct: 455 HRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN 514 Query: 430 PIKYFNNKIIC-DLVEERHK--GIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETR 486 I + + C +L+E + G++++LDEEC P ATD SF+EKL + G H F+ Sbjct: 515 FIDFGLDLQPCIELIERPNNPPGVLALLDEECWFP-KATDKSFVEKLCTEQGSHPKFQKP 573 Query: 487 KLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECF 546 K K EF ++HYAG+V Y +L KN D L ++ +L S + + + + Sbjct: 574 KQLKDK-------TEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLW 626 Query: 547 ----------LLAELENRRRPP----------TVGTQFKNSLSSLLETLISKEPSYIRCI 586 +A++ P TVG +K L L+ TL + P+++RCI Sbjct: 627 KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 686 Query: 587 KPNDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHW 646 PN K K D FL+ Q++ G++E +R+ R GF R ++ F QRY+ L + P Sbjct: 687 IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 746 Query: 647 HGPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYK 706 + +IK + P Y++G++KIF R L E+ + ++ QA + Sbjct: 747 FMDGKQACILMIKALELDPNLYRIGQSKIFFR-TGVLAHLEEERDLKITDVIMAFQAMCR 805 Query: 707 RCLGRREYVKKRQAAIKLEAHWRGALARKAIQRRKW 742 L R+ + K++Q ++ R A ++ +W Sbjct: 806 GYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 841 >gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo sapiens] Length = 1945 Score = 429 bits (1103), Expect = e-120 Identities = 267/756 (35%), Positives = 414/756 (54%), Gaps = 48/756 (6%) Query: 24 SESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQGVNFFELPPHVYA 83 +E++ + NLR+R+ LIYTY G V VNPY+ L IY+ +++Y+G E+PPH+YA Sbjct: 97 NEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYA 156 Query: 84 IADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTC---------PMTQSLQI 134 IAD AYR M + + IL +GESGAGKTE +KK+++Y AV +TQ Sbjct: 157 IADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSF 216 Query: 135 A----RDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKS 190 A +LL +NP+LEAFGNA+T++NDNSSRFGK++ I FD G VG +I +YL+EKS Sbjct: 217 AYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 276 Query: 191 RVVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWK 250 R + Q ER FHIFY ++AG +E+ S L LE Y +LS G ++ D+ + Sbjct: 277 RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNN-YTFLSNGFVPIPAAQDDEMFQE 335 Query: 251 TVSNAFSVIDFTEADLENLFGIIASVLHLGNIGF-EEDDQGCATIPDTHEIKWIAKLLGV 309 TV A +++ F+E + ++ +++SVL LGNI F +E + A++PD + + L+G+ Sbjct: 336 TV-EAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 394 Query: 310 HPSVLLEALTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNK 369 + + ++ +I+ + V T E + +A +A+AKA Y R F W++ ++N +L Sbjct: 395 NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKT 454 Query: 370 DFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIEWE 429 + +G+LDI GFE+F+ N FEQ CINY NEKLQQL EQ EY+ EGIEW Sbjct: 455 HRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN 514 Query: 430 PIKYFNNKIIC-DLVEERHK--GIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETR 486 I + + C +L+E + G++++LDEEC P ATD SF+EKL + G H F+ Sbjct: 515 FIDFGLDLQPCIELIERPNNPPGVLALLDEECWFP-KATDKSFVEKLCTEQGSHPKFQKP 573 Query: 487 KLAGPKGRKRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECF 546 K K EF ++HYAG+V Y +L KN D L ++ +L S + + + + Sbjct: 574 KQLKDK-------TEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLW 626 Query: 547 ----------LLAELENRRRPP----------TVGTQFKNSLSSLLETLISKEPSYIRCI 586 +A++ P TVG +K L L+ TL + P+++RCI Sbjct: 627 KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 686 Query: 587 KPNDRKEPSKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHW 646 PN K K D FL+ Q++ G++E +R+ R GF R ++ F QRY+ L + P Sbjct: 687 IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 746 Query: 647 HGPPAEGVERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYK 706 + +IK + P Y++G++KIF R L E+ + ++ QA + Sbjct: 747 FMDGKQACILMIKALELDPNLYRIGQSKIFFR-TGVLAHLEEERDLKITDVIMAFQAMCR 805 Query: 707 RCLGRREYVKKRQAAIKLEAHWRGALARKAIQRRKW 742 L R+ + K++Q ++ R A ++ +W Sbjct: 806 GYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 841 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 428 bits (1101), Expect = e-119 Identities = 278/785 (35%), Positives = 429/785 (54%), Gaps = 46/785 (5%) Query: 24 SESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQGVNFFELPPHVYA 83 +E++ + NL++R+ LIYTY G V +NPY+ L IY+ +E+Y+G E+PPH+YA Sbjct: 93 NEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPHIYA 152 Query: 84 IADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQSLQIARD---RLL 140 I D AYR M + + IL +GESGAGKTE +KK+++Y A +S + + +LL Sbjct: 153 ITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQGELERQLL 212 Query: 141 FSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSRVVYQNEGER 200 +NP+LEAFGNA+T++NDNSSRFGK++ I FD G VG +I +YL+EKSR + Q + ER Sbjct: 213 QANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEER 272 Query: 201 NFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWKTVSNAFSVID 260 FHIFY LL+G E + L LE + Y++LS GH DK+ ++ A ++ Sbjct: 273 TFHIFYYLLSGAGEHLKTDLLLEPYNK-YRFLSNGHVTIPGQ-QDKDMFQETMEAMRIMG 330 Query: 261 FTEADLENLFGIIASVLHLGNIGFEED---DQGCATIPDTHEIKWIAKLLGVHPSVLLEA 317 E + L +I+ VL LGNI F+++ DQ A++PD + ++ LLG++ + Sbjct: 331 IPEEEQMGLLRVISGVLQLGNIVFKKERNTDQ--ASMPDNTAAQKVSHLLGINVTDFTRG 388 Query: 318 LTHRKIEAKTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLVNKDFTRKTVI 377 + +I+ + V T E + +A +A+AKA Y R F WLV +IN +L + I Sbjct: 389 ILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFI 448 Query: 378 GLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIEWEPIKYFNNK 437 G+LDI GFE+FD N FEQ CINY NEKLQQL EQ EY+ EGIEW I + + Sbjct: 449 GILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDL 508 Query: 438 IIC-DLVEE--RHKGIISILDEECIRPGPATDLSFLEKLEEKVGKHAHFETRKLAGPKGR 494 C DL+E+ GI+++LDEEC P ATD SF+EK+ ++ G H F+ K K Sbjct: 509 QPCIDLIEKPAGPPGILALLDEECWFP-KATDKSFVEKVMQEQGTHPKFQKPKQLKDKA- 566 Query: 495 KRIGWMEFRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNIILRECF-------- 546 +F ++HYAG+V Y +L KN D L ++ +L +S + + E + Sbjct: 567 ------DFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIG 620 Query: 547 --LLAELENRRRP----------PTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEP 594 +A + P TVG +K L+ L+ TL + P+++RCI PN K+ Sbjct: 621 LDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKA 680 Query: 595 SKFDDFLIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGV 654 K D L+ Q++ G++E +R+ R GF R ++ F QRY+ L P++ P + Sbjct: 681 GKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQAC 740 Query: 655 ERLIKYIGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREY 714 +IK + Y++G++K+F R L E+ + ++ QA + L R+ + Sbjct: 741 VLMIKALELDSNLYRIGQSKVFFR-AGVLAHLEEERDLKITDVIIGFQACCRGYLARKAF 799 Query: 715 VKKRQAAIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGF--ISRNKPLCPDNEEFIVFV 772 K++Q ++ R A ++ +W R+ K +K +SR + EE +V V Sbjct: 800 AKRQQQLTAMKVLQRNCAAYLKLRNWQW-WRLFTK-VKPLLQVSRQEEEMMAKEEELVKV 857 Query: 773 RKNYI 777 R+ + Sbjct: 858 REKQL 862 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.138 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 37,250,105 Number of Sequences: 37866 Number of extensions: 1641562 Number of successful extensions: 3862 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 61 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 3353 Number of HSP's gapped (non-prelim): 159 length of query: 1022 length of database: 18,247,518 effective HSP length: 112 effective length of query: 910 effective length of database: 14,006,526 effective search space: 12745938660 effective search space used: 12745938660 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.