Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 121114298

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|121114298 cullin 4B isoform 1 [Homo sapiens]
         (913 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|121114298 cullin 4B isoform 1 [Homo sapiens]                      1786   0.0  
gi|121114302 cullin 4B isoform 2 [Homo sapiens]                      1742   0.0  
gi|57165424 cullin 4A isoform 1 [Homo sapiens]                       1243   0.0  
gi|11140811 cullin 4A isoform 2 [Homo sapiens]                       1138   0.0  
gi|4503165 cullin 3 [Homo sapiens]                                    503   e-142
gi|32307161 cullin 1 [Homo sapiens]                                   339   6e-93
gi|19482174 cullin 2 [Homo sapiens]                                   308   1e-83
gi|40254446 Vasopressin-activated calcium-mobilizing receptor-1 ...   238   1e-62
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    63   1e-09
gi|7019327 anaphase-promoting complex subunit 2 [Homo sapiens]         63   1e-09
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         57   1e-07
gi|161016767 mucin 21 [Homo sapiens]                                   56   1e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        51   4e-06
gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo...    47   6e-05
gi|40807452 peroxisome proliferator-activated receptor gamma, co...    46   1e-04
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa...    45   4e-04
gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti...    44   5e-04
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    42   0.003
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  42   0.003
gi|91982772 mucin 17 [Homo sapiens]                                    42   0.003
gi|33356174 pinin, desmosome associated protein [Homo sapiens]         42   0.003
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    41   0.004
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    41   0.004
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    41   0.004
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    41   0.004
gi|34452681 ring finger protein 10 [Homo sapiens]                      41   0.004
gi|192807286 zinc finger and BTB domain containing 4 [Homo sapiens]    41   0.004
gi|192807284 zinc finger and BTB domain containing 4 [Homo sapiens]    41   0.004
gi|169166609 PREDICTED: similar to ribonucleic acid binding prot...    40   0.008
gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]            40   0.008

>gi|121114298 cullin 4B isoform 1 [Homo sapiens]
          Length = 913

 Score = 1786 bits (4625), Expect = 0.0
 Identities = 913/913 (100%), Positives = 913/913 (100%)

Query: 1   MMSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLN 60
           MMSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLN
Sbjct: 1   MMSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLN 60

Query: 61  SSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLR 120
           SSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLR
Sbjct: 61  SSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLR 120

Query: 121 FEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS 180
           FEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS
Sbjct: 121 FEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS 180

Query: 181 TTVSSFANSKPGSAKKLVIKNFKDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEEL 240
           TTVSSFANSKPGSAKKLVIKNFKDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEEL
Sbjct: 181 TTVSSFANSKPGSAKKLVIKNFKDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEEL 240

Query: 241 YQAVENLCSYKISANLYKQLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQM 300
           YQAVENLCSYKISANLYKQLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQM
Sbjct: 241 YQAVENLCSYKISANLYKQLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQM 300

Query: 301 IMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNG 360
           IMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNG
Sbjct: 301 IMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNG 360

Query: 361 EAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKR 420
           EAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKR
Sbjct: 361 EAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKR 420

Query: 421 LEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLF 480
           LEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLF
Sbjct: 421 LEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLF 480

Query: 481 SRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKF 540
           SRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKF
Sbjct: 481 SRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKF 540

Query: 541 INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGK 600
           INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGK
Sbjct: 541 INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGK 600

Query: 601 DVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMI 660
           DVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMI
Sbjct: 601 DVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMI 660

Query: 661 QFKQYMQNQNVPGNIELTVNILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRK 720
           QFKQYMQNQNVPGNIELTVNILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRK
Sbjct: 661 QFKQYMQNQNVPGNIELTVNILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRK 720

Query: 721 LQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRR 780
           LQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRR
Sbjct: 721 LQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRR 780

Query: 781 TLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTE 840
           TLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTE
Sbjct: 781 TLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTE 840

Query: 841 RVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYME 900
           RVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYME
Sbjct: 841 RVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYME 900

Query: 901 RDKENPNQYNYIA 913
           RDKENPNQYNYIA
Sbjct: 901 RDKENPNQYNYIA 913


>gi|121114302 cullin 4B isoform 2 [Homo sapiens]
          Length = 895

 Score = 1742 bits (4512), Expect = 0.0
 Identities = 891/891 (100%), Positives = 891/891 (100%)

Query: 23  GFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSS 82
           GFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSS
Sbjct: 5   GFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSS 64

Query: 83  SSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSS 142
           SSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSS
Sbjct: 65  SSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSS 124

Query: 143 SSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLVIKNF 202
           SSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLVIKNF
Sbjct: 125 SSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKLVIKNF 184

Query: 203 KDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQ 262
           KDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQ
Sbjct: 185 KDKPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQ 244

Query: 263 ICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLP 322
           ICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLP
Sbjct: 245 ICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLP 304

Query: 323 SIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQ 382
           SIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQ
Sbjct: 305 SIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQ 364

Query: 383 DSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIA 442
           DSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIA
Sbjct: 365 DSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIA 424

Query: 443 TVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFG 502
           TVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFG
Sbjct: 425 TVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFG 484

Query: 503 STIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAEL 562
           STIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAEL
Sbjct: 485 STIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAEL 544

Query: 563 IAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSAS 622
           IAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSAS
Sbjct: 545 IAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSAS 604

Query: 623 VDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNIL 682
           VDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNIL
Sbjct: 605 VDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNIL 664

Query: 683 TMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKE 742
           TMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKE
Sbjct: 665 TMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKE 724

Query: 743 LQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDI 802
           LQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDI
Sbjct: 725 LQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDI 784

Query: 803 EDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRK 862
           EDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRK
Sbjct: 785 EDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRK 844

Query: 863 TLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 913
           TLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA
Sbjct: 845 TLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 895


>gi|57165424 cullin 4A isoform 1 [Homo sapiens]
          Length = 759

 Score = 1243 bits (3217), Expect = 0.0
 Identities = 620/749 (82%), Positives = 683/749 (91%), Gaps = 5/749 (0%)

Query: 168 ASVHHANGLAKSSTTVSSFANSKPGSA---KKLVIKNFKDKPKLPENYTDETWQKLKEAV 224
           A V   NGL K +   +  A +KPG A   KKLVIKNF+D+P+LP+NYT +TW+KL EAV
Sbjct: 13  ALVGRTNGLTKPAALAA--APAKPGGAGGSKKLVIKNFRDRPRLPDNYTQDTWRKLHEAV 70

Query: 225 EAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHIKAQIHQFREDSLDSVL 284
            A+Q+STSI+YNLEELYQAVENLCS+K+S  LYKQLRQ CEDH++AQI  FREDSLDSVL
Sbjct: 71  RAVQSSTSIRYNLEELYQAVENLCSHKVSPMLYKQLRQACEDHVQAQILPFREDSLDSVL 130

Query: 285 FLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQN 344
           FLKKI+ CWQ+HCRQMIMIRSIFLFLDRTYVLQNS LPSIWDMGLELFR HIISD+ VQ+
Sbjct: 131 FLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIWDMGLELFRTHIISDKMVQS 190

Query: 345 KTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKL 404
           KTIDGILLLIERER+GEA+DRSLLRSLL MLSDLQ+Y+DSFE +FLEETN LYAAEGQ+L
Sbjct: 191 KTIDGILLLIERERSGEAVDRSLLRSLLGMLSDLQVYKDSFELKFLEETNCLYAAEGQRL 250

Query: 405 MQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNL 464
           MQEREVPEYL+HV+KRLEEE DR+ITYLD +TQK LIA VEKQLLGEHLTAILQKGL++L
Sbjct: 251 MQEREVPEYLNHVSKRLEEEGDRVITYLDHSTQKPLIACVEKQLLGEHLTAILQKGLDHL 310

Query: 465 LDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKD 524
           LDENR+ DL+ +YQLFSRVRGG Q LLQ W EYIK FG+ IVINPEKDK MVQ+LLDFKD
Sbjct: 311 LDENRVPDLAQMYQLFSRVRGGQQALLQHWSEYIKTFGTAIVINPEKDKDMVQDLLDFKD 370

Query: 525 KVDHIIDICFLKNEKFINAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATDEELE 584
           KVDH+I++CF KNE+F+N MKE+FETFINKRPNKPAELIAK+VDSKLRAGNKEATDEELE
Sbjct: 371 KVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAGNKEATDEELE 430

Query: 585 KMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSK 644
           + LDKIMI+FRFI+GKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSK
Sbjct: 431 RTLDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSK 490

Query: 645 LEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNILTMGYWPTYVPMEVHLPPEMVKL 704
           LEGMFKDMELSKDIM+ FKQ+MQNQ+  G I+LTVNILTMGYWPTY PMEVHL PEM+KL
Sbjct: 491 LEGMFKDMELSKDIMVHFKQHMQNQSDSGPIDLTVNILTMGYWPTYTPMEVHLTPEMIKL 550

Query: 705 QEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSL 764
           QE+FK FYLGKHSGRKLQWQ+TLGH VLKAEFKEGKKE QVSLFQTLVLLMFNEG+ FS 
Sbjct: 551 QEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLLMFNEGDGFSF 610

Query: 765 EEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKIN 824
           EEIK ATGIED ELRRTLQSLACGKARVL K+PKGK++EDGDKFI N +FKHKLFRIKIN
Sbjct: 611 EEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEFKHKLFRIKIN 670

Query: 825 QIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKPA 884
           QIQMKETVEEQ STTERVFQDRQYQIDAAIVRIMKMRKTL HNLLVSE+YNQLKFPVKP 
Sbjct: 671 QIQMKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELYNQLKFPVKPG 730

Query: 885 DLKKRIESLIDRDYMERDKENPNQYNYIA 913
           DLKKRIESLIDRDYMERDK+NPNQY+Y+A
Sbjct: 731 DLKKRIESLIDRDYMERDKDNPNQYHYVA 759


>gi|11140811 cullin 4A isoform 2 [Homo sapiens]
          Length = 659

 Score = 1138 bits (2943), Expect = 0.0
 Identities = 564/658 (85%), Positives = 613/658 (93%)

Query: 256 LYKQLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYV 315
           LYKQLRQ CEDH++AQI  FREDSLDSVLFLKKI+ CWQ+HCRQMIMIRSIFLFLDRTYV
Sbjct: 2   LYKQLRQACEDHVQAQILPFREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYV 61

Query: 316 LQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSML 375
           LQNS LPSIWDMGLELFR HIISD+ VQ+KTIDGILLLIERER+GEA+DRSLLRSLL ML
Sbjct: 62  LQNSTLPSIWDMGLELFRTHIISDKMVQSKTIDGILLLIERERSGEAVDRSLLRSLLGML 121

Query: 376 SDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQT 435
           SDLQ+Y+DSFE +FLEETN LYAAEGQ+LMQEREVPEYL+HV+KRLEEE DR+ITYLD +
Sbjct: 122 SDLQVYKDSFELKFLEETNCLYAAEGQRLMQEREVPEYLNHVSKRLEEEGDRVITYLDHS 181

Query: 436 TQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWI 495
           TQK LIA VEKQLLGEHLTAILQKGL++LLDENR+ DL+ +YQLFSRVRGG Q LLQ W 
Sbjct: 182 TQKPLIACVEKQLLGEHLTAILQKGLDHLLDENRVPDLAQMYQLFSRVRGGQQALLQHWS 241

Query: 496 EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 555
           EYIK FG+ IVINPEKDK MVQ+LLDFKDKVDH+I++CF KNE+F+N MKE+FETFINKR
Sbjct: 242 EYIKTFGTAIVINPEKDKDMVQDLLDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKR 301

Query: 556 PNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRL 615
           PNKPAELIAK+VDSKLRAGNKEATDEELE+ LDKIMI+FRFI+GKDVFEAFYKKDLAKRL
Sbjct: 302 PNKPAELIAKHVDSKLRAGNKEATDEELERTLDKIMILFRFIHGKDVFEAFYKKDLAKRL 361

Query: 616 LVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNI 675
           LVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIM+ FKQ+MQNQ+  G I
Sbjct: 362 LVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMVHFKQHMQNQSDSGPI 421

Query: 676 ELTVNILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAE 735
           +LTVNILTMGYWPTY PMEVHL PEM+KLQE+FK FYLGKHSGRKLQWQ+TLGH VLKAE
Sbjct: 422 DLTVNILTMGYWPTYTPMEVHLTPEMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAE 481

Query: 736 FKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAK 795
           FKEGKKE QVSLFQTLVLLMFNEG+ FS EEIK ATGIED ELRRTLQSLACGKARVL K
Sbjct: 482 FKEGKKEFQVSLFQTLVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIK 541

Query: 796 NPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIV 855
           +PKGK++EDGDKFI N +FKHKLFRIKINQIQMKETVEEQ STTERVFQDRQYQIDAAIV
Sbjct: 542 SPKGKEVEDGDKFIFNGEFKHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIV 601

Query: 856 RIMKMRKTLSHNLLVSEVYNQLKFPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 913
           RIMKMRKTL HNLLVSE+YNQLKFPVKP DLKKRIESLIDRDYMERDK+NPNQY+Y+A
Sbjct: 602 RIMKMRKTLGHNLLVSELYNQLKFPVKPGDLKKRIESLIDRDYMERDKDNPNQYHYVA 659


>gi|4503165 cullin 3 [Homo sapiens]
          Length = 768

 Score =  503 bits (1296), Expect = e-142
 Identities = 291/749 (38%), Positives = 440/749 (58%), Gaps = 48/749 (6%)

Query: 208 LPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDH 267
           + E Y +  W  LK A++ IQ   +   + EELY+    +  +K    LY  LR++  +H
Sbjct: 25  MDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEH 84

Query: 268 IKAQIHQFREDSLDSVL--FLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPSIW 325
           +   I++ RED L+S+   FL+ +++ W +H   M+MIR I +++DR YV QN++  +++
Sbjct: 85  L---INKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNV-ENVY 140

Query: 326 DMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDL-----QI 380
           ++GL +FR  ++    +++     +L +I RER GE +DR  +R+   ML  L      +
Sbjct: 141 NLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSV 200

Query: 381 YQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSL 440
           Y++ FE  FLE +   +  E QK + E     Y+  V  R+ EE +R++  LD++T++ +
Sbjct: 201 YEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPI 260

Query: 441 IATVEKQLLGEHLTAILQ---KGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEY 497
           +  VE++L+ +H+  I++    GL ++L   + +DL  +Y+LFSRV  G++ + +    Y
Sbjct: 261 VKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSY 320

Query: 498 IKAFGSTIVINPEKDKTMV---QELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINK 554
           ++  G  +V    + K  V   Q LLD K + D  +   F  +  F   +   FE F+N 
Sbjct: 321 LREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNL 380

Query: 555 RPNKPAELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKR 614
               P E ++ ++D KL+ G K  T++E+E +LDK M++FRF+  KDVFE +YK+ LA+R
Sbjct: 381 NSRSP-EYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARR 439

Query: 615 LLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVP-G 673
           LL  KS S D+EK+M+SKLK ECG  FTSKLEGMF+DM +S   M +F+Q++Q   V  G
Sbjct: 440 LLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLG 499

Query: 674 NIELTVNILTMGYWPTY-VPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVL 732
            ++LTV +LT GYWPT     + ++PP      EIF+ FYL KHSGR+L  Q  +G   L
Sbjct: 500 GVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADL 559

Query: 733 KAEF-----KEGKKE-----------------LQVSLFQTLVLLMFNEGEEFSLEEIKQA 770
            A F     KE   E                 LQVS FQ  +L++FN  E+++ EEI+Q 
Sbjct: 560 NATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQE 619

Query: 771 TGIEDGELRRTLQSLACGK--ARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQM 828
           T I + EL R LQSLACGK   RVL K PK K+IE+G  F  ND F  KL R+KI  +  
Sbjct: 620 TDIPERELVRALQSLACGKPTQRVLTKEPKSKEIENGHIFTVNDQFTSKLHRVKIQTVAA 679

Query: 829 K--ETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLK--FPVKPA 884
           K  E+  E+  T ++V  DR+++I+AAIVRIMK RK + HN+LV+EV  QLK  F   P 
Sbjct: 680 KQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPV 739

Query: 885 DLKKRIESLIDRDYMERDKENPNQYNYIA 913
            +KKRIE LI+R+Y+ R  E+   Y Y+A
Sbjct: 740 VIKKRIEGLIEREYLARTPEDRKVYTYVA 768


>gi|32307161 cullin 1 [Homo sapiens]
          Length = 776

 Score =  339 bits (870), Expect = 6e-93
 Identities = 239/768 (31%), Positives = 391/768 (50%), Gaps = 77/768 (10%)

Query: 214 DETWQKLKEAVEAIQNSTSI-KYNLEELYQAVENLCSYKISAN----------------- 255
           D+ W  L+  ++ +    S+ K    ELY  V N C+    +N                 
Sbjct: 18  DQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQT 77

Query: 256 ----------LYKQLRQICEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRS 305
                     LYK+L++  ++++   + +  ED +D  + LK   + W+++     ++  
Sbjct: 78  PGGAQFVGLELYKRLKEFLKNYL-TNLLKDGEDLMDESV-LKFYTQQWEDYRFSSKVLNG 135

Query: 306 IFLFLDRTYVLQN-----SMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNG 360
           I  +L+R +V +        +  I+ + L  +R  +   + +  +  + +L LIE+ERNG
Sbjct: 136 ICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLF--RPLNKQVTNAVLKLIEKERNG 193

Query: 361 EAIDRSLLRSLLSMLSDL--------------QIYQDSFEQRFLEETNRLYAAEGQKLMQ 406
           E I+  L+  ++    +L               +Y++SFE +FL +T R Y  E  + +Q
Sbjct: 194 ETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQ 253

Query: 407 EREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNLLD 466
           +  V EY+     RL EE  R+  YL ++TQ  L    E+ L+ +HL  I      NLLD
Sbjct: 254 QNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLE-IFHTEFQNLLD 312

Query: 467 ENRIQDLSLLYQLFSRVRGGVQVLLQ--------QWIEYIKAFGSTIVINPEKDKTMVQE 518
            ++ +DL  +Y L SR++ G+  L +        Q +  I+  G   + +P   K  VQ 
Sbjct: 313 ADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAALNDP---KMYVQT 369

Query: 519 LLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRP--------NKPAELIAKYVDSK 570
           +LD   K + ++   F  +  F+ A+ +A   FIN           +K  EL+A+Y DS 
Sbjct: 370 VLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSL 429

Query: 571 LRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSML 630
           L+  +K   + ELE  L+++M++F++I  KDVF+ FY K LAKRL+   SAS DAE SM+
Sbjct: 430 LKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMI 489

Query: 631 SKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQYMQNQNVPGNIELTVNILTMGYWPTY 690
           SKLK  CG  +TSKL+ MF+D+ +SKD+  QFK+++ N   P +++ ++ +L+ G WP  
Sbjct: 490 SKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSE-PLDLDFSIQVLSSGSWPFQ 548

Query: 691 VPMEVHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQT 750
                 LP E+ +  + F  FY  +HSGRKL W   L    L     + +  LQ S FQ 
Sbjct: 549 QSCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQM 608

Query: 751 LVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLA-KNPKGKDIE-DGDKF 808
            +LL +N  + ++++++  +T I+   L + LQ L   K  VL  +N    ++E   D  
Sbjct: 609 AILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTL 668

Query: 809 I-CNDDFKHKLFRIKINQIQMKETVEEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHN 867
           I     +K+K  R+ IN     E  +EQ +T + + +DR+  I AAIVRIMKMRK L H 
Sbjct: 669 IKLYLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQ 728

Query: 868 LLVSEVYNQLKFPVKP--ADLKKRIESLIDRDYMERDKENPNQYNYIA 913
            L+ EV  QL    KP    +KK I+ LI+++Y+ER     + Y+Y+A
Sbjct: 729 QLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA 776


>gi|19482174 cullin 2 [Homo sapiens]
          Length = 745

 Score =  308 bits (790), Expect = 1e-83
 Identities = 212/743 (28%), Positives = 381/743 (51%), Gaps = 51/743 (6%)

Query: 214 DETWQKLKEAVEAIQNSTSI-KYNLEELYQAVENLC---SYKISANLYKQLRQICEDHIK 269
           DETW KL   ++A+     + +    + +  +  LC      +   LY + +   E+H++
Sbjct: 11  DETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVR 70

Query: 270 AQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSM--------- 320
             +H+   +S + VL +    R W+ + +    +  ++ +L+  ++ +N +         
Sbjct: 71  -HLHKRVLESEEQVLVM--YHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGY 127

Query: 321 --------LPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLL 372
                   L  I ++ L+++R  ++  + +Q   I  +L  I+ +R GE  ++ ++  ++
Sbjct: 128 GGVDMNEPLMEIGELALDMWRKLMV--EPLQAILIRMLLREIKNDRGGEDPNQKVIHGVI 185

Query: 373 SMLSD---------LQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEE 423
           +             L+ YQ+ FE  FL ET   Y  E   L+QE    +Y+  V  RL++
Sbjct: 186 NSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKD 245

Query: 424 EADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRV 483
           E  R   YL  ++   +I   +++++ +HL   L    +N++ + +  D++ +Y L   V
Sbjct: 246 EEIRCRKYLHPSSYTKVIHECQQRMVADHLQ-FLHAECHNIIRQEKKNDMANMYVLLRAV 304

Query: 484 RGGVQVLLQQWIEYIKAFG--STIVINPEKDKTM-VQELLDFKDKVDHIIDICFLKNEKF 540
             G+  ++Q+   +I   G  +T  +  E   T+ V+ +L+   K   +I+     ++ F
Sbjct: 305 STGLPHMIQELQNHIHDEGLRATSNLTQENMPTLFVESVLEVHGKFVQLINTVLNGDQHF 364

Query: 541 INAMKEAFETFINKRPNKPA----ELIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRF 596
           ++A+ +A  + +N R  K      EL+AKY D+ L+   K  T+ E+E  L   + +F++
Sbjct: 365 MSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVEDRLTSFITVFKY 424

Query: 597 IYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSK 656
           I  KDVF+ FY + LAKRL+ G S S+D+E++M++KLK  CG  FTSKL  M+ DM +S 
Sbjct: 425 IDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSA 484

Query: 657 DIMIQFKQYMQNQN--VPGNIELTVNILTMGYWP-TYVPMEVH-LPPEMVKLQEIFKTFY 712
           D+  +F  +++NQ+  +   I   + +L  G WP T  P     +P E+ K  ++F+ FY
Sbjct: 485 DLNNKFNNFIKNQDTVIDLGISFQIYVLQAGAWPLTQAPSSTFAIPQELEKSVQMFELFY 544

Query: 713 LGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATG 772
               SGRKL W   L    +K  +        V+ +Q  VLL FN  E  S +E++ +T 
Sbjct: 545 SQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAVLLAFNNSETVSYKELQDSTQ 604

Query: 773 IEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDFKHKLFRIKINQIQMKETV 832
           + + EL +T++SL     +++  + + +DI+    F  N +F  K  + KI     K+T 
Sbjct: 605 MNEKELTKTIKSLL--DVKMINHDSEKEDIDAESSFSLNMNFSSKRTKFKITTSMQKDTP 662

Query: 833 EEQASTTERVFQDRQYQIDAAIVRIMKMRKTLSHNLLVSEVYNQLKFPVKP--ADLKKRI 890
           +E   T   V +DR+  + AAIVRIMK RK L HN L+ EV +Q +    P  + +KK I
Sbjct: 663 QEMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSISMIKKCI 722

Query: 891 ESLIDRDYMERDKENPNQYNYIA 913
           E LID+ Y+ER + + ++Y+Y+A
Sbjct: 723 EVLIDKQYIERSQASADEYSYVA 745


>gi|40254446 Vasopressin-activated calcium-mobilizing receptor-1
           [Homo sapiens]
          Length = 780

 Score =  238 bits (608), Expect = 1e-62
 Identities = 209/773 (27%), Positives = 378/773 (48%), Gaps = 81/773 (10%)

Query: 214 DETWQKLKEAVEAIQNSTSI-KYNLEELYQAVENLCSY--KISANLYKQLRQICEDHIKA 270
           ++ W  ++  V  +    S+ K    +L+  V  +C +  K  A +++ L++   + IK 
Sbjct: 16  EDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQ 75

Query: 271 QIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYV-LQNSMLPS------ 323
              +      D+ L LK     W+    Q  ++   F  L+ T +  Q S   S      
Sbjct: 76  AQARVLSHQDDTAL-LKAYIVEWRKFFTQCDILPKPFCQLEITLMGKQGSNKKSNVEDSI 134

Query: 324 IWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLL----RSLLSMLSD-- 377
           +  + L+ +   I S+  ++N+  D  + L+  ER GEA D  L+     S +++ S+  
Sbjct: 135 VRKLMLDTWNESIFSN--IKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPE 192

Query: 378 --LQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQT 435
             LQIY+D+FE+ +L+ T R Y  +    +Q+  V  Y+ + + +L+EE  R + YL+  
Sbjct: 193 DKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETR 252

Query: 436 TQKSLIATVEKQLLGEHLTAILQKGL---NNLLDENRIQDLSLLYQLFSRVRGGVQVLLQ 492
            + + +  + +  +   +T+  +  L     ++  N  + L L++ L  +V  G++ +L+
Sbjct: 253 RECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLK 312

Query: 493 QWIEYIKAFG--------STIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAM 544
              E+I + G         TI  + EK    V++LL   ++   ++   F  + +F+ A 
Sbjct: 313 DLEEHIISAGLADMVAAAETITTDSEK---YVEQLLTLFNRFSKLVKEAFQDDPRFLTAR 369

Query: 545 KEAFETFIN--------------------KRPNKPAELIAKYVDSKLRAG--NKEATDEE 582
            +A++  +N                    +  +K  EL+A Y D  LR    +K+ T EE
Sbjct: 370 DKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPELLANYCDMLLRKTPLSKKLTSEE 429

Query: 583 LEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECG--AA 640
           +E  L +++++ +++  KDVF  ++K  L +RL++  SA  + E++M+  L+ E G  A 
Sbjct: 430 IEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLR-EVGMPAD 488

Query: 641 FTSKLEGMFKDMELSKDIMIQFKQYMQNQN--VPGNIELTVNILTMGYWP-TYVPMEVHL 697
           + +KL  MF+D+++S+D+   FK+  +N    +P +  + + IL  G W  +   + V L
Sbjct: 489 YVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPAD-SVNIKILNAGAWSRSSEKVFVSL 547

Query: 698 PPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFN 757
           P E+  L    + FY   HSGRKL W   + + ++  + + G+ +L+V+ FQ  VL  +N
Sbjct: 548 PTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWN 607

Query: 758 E--GEEFSLEEIKQATGIEDGELRRTLQSLACG---KARVLAKNPK---GKDIEDGDKFI 809
           +   E+ S E +K AT + D ELRRTL SL      K +VL   P+    KD  +G  F 
Sbjct: 608 QRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLFS 667

Query: 810 CNDDFK-----HKLFRIKINQIQMKETVEE--QASTTERVFQDRQYQIDAAIVRIMKMRK 862
            N +F          R KIN I   +   E  +    E + Q R  +   AI++IMKMRK
Sbjct: 668 VNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMRK 727

Query: 863 TLSHNLLVSEVYNQLK--FPVKPADLKKRIESLIDRDYMERDKENPNQYNYIA 913
            +S+  L +E+   LK  F  +   +K++IE LI+  Y+ RD+ + N + Y+A
Sbjct: 728 KISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA 780


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 51/196 (26%), Positives = 91/196 (46%), Gaps = 4/196 (2%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            S SS S DG+D +++   D   SS S  ++ ++    S+   +++ +  +S      NSS
Sbjct: 842  SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901

Query: 63   SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122
             S SS+SSN  +  DS++SS S+      D+++ S SS     S ++ S          +
Sbjct: 902  DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961

Query: 123  DTLEFVGFDAKMAEESSSSSSS----SSPTAATSQQQQLKNKSILISSVASVHHANGLAK 178
             +      D+  ++ S SS+SS    SS ++ +S      N S    S  S   +N    
Sbjct: 962  SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021

Query: 179  SSTTVSSFANSKPGSA 194
            S+++ SS ++    S+
Sbjct: 1022 SNSSDSSNSSDSSDSS 1037



 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 51/192 (26%), Positives = 84/192 (43%), Gaps = 1/192 (0%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            S SS S D +D  ++ S D   SS S  ++ ++    S+   N+S +  +S      NSS
Sbjct: 960  SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019

Query: 63   SSS-SSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121
             SS SS+SSN  +  DS+ SS S+      DS+  S SS     S ++ S          
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079

Query: 122  EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSST 181
            + +      D+  + +SS SS SS  + ++       +     SS +S    +  +  S+
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1139

Query: 182  TVSSFANSKPGS 193
              S  ++S   S
Sbjct: 1140 NSSDSSDSSESS 1151



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 53/205 (25%), Positives = 91/205 (44%), Gaps = 19/205 (9%)

Query: 3   SQSSGSGDGNDD-EATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKK--RKL 59
           S SS S D +D  +++ S D   SS S S ++ ++   S +D  + ++   S+       
Sbjct: 596 SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSD 655

Query: 60  NSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKL 119
           +S SS+SSNSS+  +  DS+ SSSS+      DS+  S SS                   
Sbjct: 656 SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS----------------NSS 699

Query: 120 RFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKS 179
              D+ +    D+  + +SS+S+SS S ++ +S      N S    S  S + ++    S
Sbjct: 700 ESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 759

Query: 180 STTVSSFANSKPGSAKKLVIKNFKD 204
            ++ SS ++    S+      N  D
Sbjct: 760 DSSNSSDSSDSSDSSDSSDSSNSSD 784



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 56/207 (27%), Positives = 95/207 (45%), Gaps = 8/207 (3%)

Query: 3   SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
           S+SS S D +D +++ S D   S+ S S ++ + +  S+   N+S +  +S      +SS
Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSD--SSDSSNSSDSSDSSDSSNSSDSS 756

Query: 63  SSS-SSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121
            SS SSNSS+  +  DS+ SS S+      DS++ S SS     S +++S          
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS-DSSDSSDS 815

Query: 122 EDTLEFVGFDAKMAEESSSSSSSS----SPTAATSQQQQLKNKSILISSVASVHHANGLA 177
            D+      D+  + +SS SS+SS    S  ++        N+S   +S  S   ++   
Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875

Query: 178 KSSTTVSSFANSKPGSAKKLVIKNFKD 204
            S ++ SS +N    S+      N  D
Sbjct: 876 SSDSSDSSDSNESSNSSDSSDSSNSSD 902



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 48/191 (25%), Positives = 82/191 (42%), Gaps = 5/191 (2%)

Query: 3   SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
           S SS S D +D +++ S D   SS S  ++ ++    S+   + S +  ++      +S 
Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866

Query: 63  SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122
           SS SS+SSN  +  DS+ S+ S+      DS++ S S      S  +S+           
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD-----SSDSSNSSDSSDSSNSS 921

Query: 123 DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 182
           D+ E            SS+SS SS ++ +S      N S   +S  S    +  +  S+ 
Sbjct: 922 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981

Query: 183 VSSFANSKPGS 193
            S  ++S   S
Sbjct: 982 SSDSSDSSDSS 992



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 51/199 (25%), Positives = 83/199 (41%), Gaps = 8/199 (4%)

Query: 3   SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
           S SS S D +D +++ S     S  S S ++ + +  S+   N+S +  +S      +SS
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSS 617

Query: 63  SSSSSNSSNEREDFDS--------TSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVP 114
            SS S S + + + DS        +S S+S+      DS+  S SS     S ++ S   
Sbjct: 618 DSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDS 677

Query: 115 IQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHAN 174
                    +      D+  + ESS SS SS   ++ S      N S   SS +S    +
Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737

Query: 175 GLAKSSTTVSSFANSKPGS 193
             +  S+  S  +NS   S
Sbjct: 738 SNSSDSSDSSDSSNSSDSS 756



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 51/193 (26%), Positives = 89/193 (46%), Gaps = 8/193 (4%)

Query: 3   SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
           S SS S D +D  ++ S +   SS S  ++ ++    S+   ++S +  +S      +SS
Sbjct: 747 SDSSNSSDSSD--SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804

Query: 63  SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122
           +SS S+ S++  D DS++SS S+      DS++ S SS     S  + S        R +
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDS----DSSNRSD 860

Query: 123 DTLEFVGFDAKMAEES--SSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS 180
            +      D+  +  S  SS SS S+ ++ +S      N S   SS +S    +  + +S
Sbjct: 861 SSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 920

Query: 181 TTVSSFANSKPGS 193
           +  S  +NS   S
Sbjct: 921 SDSSESSNSSDNS 933



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 49/193 (25%), Positives = 85/193 (44%), Gaps = 2/193 (1%)

Query: 3    SQSSGSGDGNDD-EATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61
            S SS S D +D  +++ S D   SS S  ++ ++    S+   ++S +  +S      +S
Sbjct: 1055 SNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1114

Query: 62   SSSS-SSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLR 120
            S SS SSNSS+  +  DS+ SS S+      DS+  S SS     S ++ S         
Sbjct: 1115 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDS 1174

Query: 121  FEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS 180
             + +      D+  + +SS SS SS  + ++       +     SS +S    +  +  S
Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNES 1234

Query: 181  TTVSSFANSKPGS 193
            +  S  ++S   S
Sbjct: 1235 SDSSDSSDSSDSS 1247



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 51/195 (26%), Positives = 89/195 (45%), Gaps = 6/195 (3%)

Query: 3   SQSSGSGD-GNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61
           S S+G+G+ GNDD   +    G S  S S ++ +     ++D + S +  +++     + 
Sbjct: 524 SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSD--SD 581

Query: 62  SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLG-VSVAASSHVPIQKKLR 120
           SS S S+ S++ +  DS++SS S+      DS+  S SS      S + S       K  
Sbjct: 582 SSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSD 641

Query: 121 FEDTLEFVGFDAKMAEESSSSSSS--SSPTAATSQQQQLKNKSILISSVASVHHANGLAK 178
             D+      D   + +SS+SS+S  SS ++ +S      + S    S  S   +N    
Sbjct: 642 SSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701

Query: 179 SSTTVSSFANSKPGS 193
           S ++ SS ++S   S
Sbjct: 702 SDSSDSSDSDSSDSS 716



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 51/188 (27%), Positives = 83/188 (44%), Gaps = 4/188 (2%)

Query: 3    SQSSGSGDGNDDE-ATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61
            S SS S D +D   ++ S D   SS S  ++ ++    S+   N+S +  +S      +S
Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SS 1136

Query: 62   SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121
             SS+SS+SS+  E  DS+ SS S+      DS+  S SS     S ++ S          
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196

Query: 122  EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSST 181
            + +      D+  + +SS SS SS  ++ +S        S    S  S   +N    S +
Sbjct: 1197 DSSDSSDSSDSSDSSDSSDSSDSSD-SSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDS 1255

Query: 182  TVSSFANS 189
            + SS + S
Sbjct: 1256 SDSSDSTS 1263



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 54/201 (26%), Positives = 82/201 (40%), Gaps = 19/201 (9%)

Query: 3   SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTST---------TPPTS 53
           S S G    N DE   SKD G  S S  A     +  S T+ + S             + 
Sbjct: 485 SSSRGDASYNSDE---SKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSD 541

Query: 54  AKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHV 113
           + K K +SS S SS+SSN  +  DS+ S SS       DS S S S      S  +S   
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSS-------DSNSSSDSDSSDSDSSDSSDSD 594

Query: 114 PIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHA 173
                   + +      D+  + +SS S S SS + + S     K+ S   +S  S  ++
Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS 654

Query: 174 NGLAKSSTTVSSFANSKPGSA 194
           +    S+++ SS ++    S+
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSS 675



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 29/100 (29%), Positives = 51/100 (51%), Gaps = 2/100 (2%)

Query: 3    SQSSGSGDGNDDE-ATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61
            S SS S D +D   ++ S D   SS S  ++ ++    S+   ++S +  +S      +S
Sbjct: 1166 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1225

Query: 62   SSSS-SSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSS 100
            S SS S+ SS+  +  DS+ SS+S+      DS+  ++ S
Sbjct: 1226 SDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDS 1265



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 40/192 (20%), Positives = 75/192 (39%), Gaps = 7/192 (3%)

Query: 5   SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQE-VRSATDGNTSTTPPTSAKKRKLNSSS 63
           S  + DG D      K      P+ S  +   +   S +D N+S+    S    +   + 
Sbjct: 443 SDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNG 502

Query: 64  SSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFED 123
           + S +   E +D DSTS ++++      ++ +        G   + SS           D
Sbjct: 503 NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD 562

Query: 124 TLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTV 183
           + +    D+  +  SS S SS S ++ +S      + +   SS +S       +  S+  
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSD------SSDSSDS 616

Query: 184 SSFANSKPGSAK 195
           S  ++SK  S+K
Sbjct: 617 SDSSDSKSDSSK 628


>gi|7019327 anaphase-promoting complex subunit 2 [Homo sapiens]
          Length = 822

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 53/189 (28%), Positives = 86/189 (45%), Gaps = 3/189 (1%)

Query: 597 IYG-KDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELS 655
           IYG KD+F   Y+  LA RLL   S S + E   +  LK   G A     E M KDM  S
Sbjct: 508 IYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADS 567

Query: 656 KDIMIQFKQYMQNQNVPGNIELTVN--ILTMGYWPTYVPMEVHLPPEMVKLQEIFKTFYL 713
           + I    ++  + +         V   IL+  +WP +   ++ +P ++    E +   Y 
Sbjct: 568 RRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALEAYCKKYE 627

Query: 714 GKHSGRKLQWQSTLGHCVLKAEFKEGKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGI 773
              + R L W+ TLG   +  E  +    + V+  Q ++LL F +   ++LEE+ +A  +
Sbjct: 628 QLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLYFQDQASWTLEELSKAVKM 687

Query: 774 EDGELRRTL 782
               LRR +
Sbjct: 688 PVALLRRRM 696


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 34/98 (34%), Positives = 54/98 (55%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            S SSGS    ++E   + DGG  +   + +AA+    S    ++S++  +S+     +SS
Sbjct: 2574 SSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSS 2633

Query: 63   SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSS 100
            SSSSS+SS+      S+SSSSS+       S+S S+SS
Sbjct: 2634 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 14/153 (9%)

Query: 13   DDEATTSKDGGFSSPSPSAAAAAQEVRS------------ATDGNTSTTPPTSAKKRKLN 60
            + E+++S   G SS S S++++  E                T G   +   + A     +
Sbjct: 2556 ESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASS 2615

Query: 61   SSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLR 120
            SSSSSSS+SS+      S+SSSSS+       S+S S+SS     S ++SS         
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSS--SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTT 2673

Query: 121  FEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQ 153
             ED+      +A  A  +  S+ ++ PT AT Q
Sbjct: 2674 DEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQ 2706



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 51/202 (25%), Positives = 84/202 (41%), Gaps = 38/202 (18%)

Query: 18   TSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFD 77
            T +D G +  SP  A A Q+    ++ ++S++  +S+     +SSSSSSS S  E E+  
Sbjct: 2534 TFEDSG-NPKSPDKAQAEQDGAEESESSSSSSSGSSS-----SSSSSSSSGSETEGEEEG 2587

Query: 78   STS------------SSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTL 125
              +            S++S+    P  S+S S+SS     S ++SS              
Sbjct: 2588 DKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSS-------------- 2633

Query: 126  EFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSS 185
                  +  +  SSSSSSSSS ++++S      + S   SS +S    +    S    + 
Sbjct: 2634 ------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAP 2687

Query: 186  FANSKPGSAKKLVIKNFKDKPK 207
               + P +   L  K  K   K
Sbjct: 2688 APTAGPSAQAALPTKATKQAGK 2709



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 27/115 (23%), Positives = 56/115 (48%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            S  + S   +   +++S     SS S S+++++    S++  ++S++  +S+     +SS
Sbjct: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2665

Query: 63   SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQK 117
            SSSSS++++E     S   ++  P   P   A+  T +         S+H P +K
Sbjct: 2666 SSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKK 2720



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 51/211 (24%), Positives = 85/211 (40%), Gaps = 39/211 (18%)

Query: 1    MMSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTP---------- 50
            ++ +  G+G   + ++  S   G   P+  ++        ATDG+ +  P          
Sbjct: 2482 LLREDPGAGGWQEPKSLLSL--GSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSG 2539

Query: 51   ----PTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVS 106
                P  A+  +  +  S SS+SS+      S+SSSSS    +  +    +    C G  
Sbjct: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGC-GTG 2598

Query: 107  ----VAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSI 162
                 AASS                    A  A  SSSSSSSSS ++++S      + S 
Sbjct: 2599 GRNCSAASSRA------------------ASPASSSSSSSSSSSSSSSSSSSSSSSSSSS 2640

Query: 163  LISSVASVHHANGLAKSSTTVSSFANSKPGS 193
              SS +S   ++  + SS++ SS ++S   S
Sbjct: 2641 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 25/186 (13%)

Query: 5   SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64
           SSG+G   + E++T+  G  ++ +  ++  +  + + T+  +ST  P+S      NS SS
Sbjct: 249 SSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESST--PSSGANTATNSESS 306

Query: 65  SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124
           ++S+ +N   + DS+++SS        +S S +TSS   G S A +S          E +
Sbjct: 307 TTSSGANTATNSDSSTTSSGAS--TATNSESSTTSS---GASTATNS----------ESS 351

Query: 125 LEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVS 184
               G  A  A  S SS++SS  + AT+      ++S  +SS AS    +  + +S+  S
Sbjct: 352 TTSSG--ASTATNSGSSTTSSGTSTATN------SESSTVSSGASTATTSESSTTSSGAS 403

Query: 185 SFANSK 190
           +  NS+
Sbjct: 404 TATNSE 409



 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 49/193 (25%), Positives = 82/193 (42%), Gaps = 14/193 (7%)

Query: 5   SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64
           SSG+G   + E++T   G  +  +  ++  +    +AT+  +STT   +      +SS++
Sbjct: 264 SSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTT 323

Query: 65  SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124
           SS  S+    +  +TSS +ST      +S S +TSS     + + SS             
Sbjct: 324 SSGASTATNSESSTTSSGAST----ATNSESSTTSSGASTATNSGSSTTSSGTSTATNSE 379

Query: 125 LEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVS 184
              V   A  A  S SS++SS  + AT+ +          SS  S   +      S+T S
Sbjct: 380 SSTVSSGASTATTSESSTTSSGASTATNSE----------SSTVSSGASTATNSESSTTS 429

Query: 185 SFANSKPGSAKKL 197
           S AN+   S   +
Sbjct: 430 SGANTATNSGSSV 442



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 46/190 (24%), Positives = 83/190 (43%), Gaps = 9/190 (4%)

Query: 5   SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64
           SSG+    + E++T+  G  ++ +  ++  +    +AT+  +STT   ++      SS++
Sbjct: 294 SSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTT 353

Query: 65  SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124
           SS  S+       +TSS +ST      +S S + SS     + + SS             
Sbjct: 354 SSGASTATNSGSSTTSSGTST----ATNSESSTVSSGASTATTSESSTTSSGASTATNSE 409

Query: 125 LEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVS 184
              V   A  A  S SS++SS    AT+    + +     +++  +H  +  A  ST VS
Sbjct: 410 SSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSA--STAVS 467

Query: 185 SFANSKPGSA 194
               +KPG +
Sbjct: 468 ---EAKPGGS 474



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 47/190 (24%), Positives = 89/190 (46%), Gaps = 18/190 (9%)

Query: 5   SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64
           SSG     + E++T   G  ++ +  ++  +    +AT+ ++STT   ++      SS++
Sbjct: 279 SSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTT 338

Query: 65  SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124
           SS  S+    +  +TSS +ST      +S S +TSS   G S A +S          E +
Sbjct: 339 SSGASTATNSESSTTSSGAST----ATNSGSSTTSS---GTSTATNS----------ESS 381

Query: 125 LEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVS 184
               G       ESS++SS +S TA  S+   + + +   ++  S   ++G   ++ + S
Sbjct: 382 TVSSGASTATTSESSTTSSGAS-TATNSESSTVSSGASTATNSESSTTSSGANTATNSGS 440

Query: 185 SFANSKPGSA 194
           S  ++  G+A
Sbjct: 441 SVTSAGSGTA 450



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 46/194 (23%), Positives = 78/194 (40%), Gaps = 14/194 (7%)

Query: 5   SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64
           SSG     + E++T+  G  ++ +  ++  +    +AT+ ++STT   ++     +SS++
Sbjct: 99  SSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTT 158

Query: 65  SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124
           SS  S+    +  +TSS +ST       + S   S+     S   SS            T
Sbjct: 159 SSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTT 218

Query: 125 LEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVS 184
               G     A  S SS++SS  + AT+ +          SS  S          S+T S
Sbjct: 219 SNGAG----TATNSESSTTSSGASTATNSE----------SSTPSSGAGTATNSESSTTS 264

Query: 185 SFANSKPGSAKKLV 198
           S A +   S    V
Sbjct: 265 SGAGTATNSESSTV 278



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 39/190 (20%), Positives = 88/190 (46%), Gaps = 3/190 (1%)

Query: 5   SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64
           SS +    + E++T+  G  ++ +  ++  +    +AT+  +STT  +S      NS S 
Sbjct: 159 SSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTT--SSGASTATNSESR 216

Query: 65  SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124
           ++SN +    + +S+++SS        +S++PS+ +     S ++++          E +
Sbjct: 217 TTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESS 276

Query: 125 LEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVS 184
               G       ESS+ SS ++ TA  S+     + +   ++  S   ++G + ++ + S
Sbjct: 277 TVSSGISTVTNSESSTPSSGAN-TATNSESSTTSSGANTATNSDSSTTSSGASTATNSES 335

Query: 185 SFANSKPGSA 194
           S  +S   +A
Sbjct: 336 STTSSGASTA 345



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 47/191 (24%), Positives = 84/191 (43%), Gaps = 5/191 (2%)

Query: 5   SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64
           S+G     + E  T+  G  ++ +   +  +  +  AT+  +STT   ++      SS+ 
Sbjct: 69  SNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTP 128

Query: 65  SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124
           SS  S+    D  +TSS +ST      +S S +TSS     + + SS             
Sbjct: 129 SSGASTATNSDSSTTSSGAST----ATNSDSSTTSSEASTATNSESSTTSSGASTATNSE 184

Query: 125 LEFVGFDAKMAEES-SSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTV 183
              V   A  A  S SS++SS + TA  S+ +   N +   ++  S   ++G + ++ + 
Sbjct: 185 SSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSE 244

Query: 184 SSFANSKPGSA 194
           SS  +S  G+A
Sbjct: 245 SSTPSSGAGTA 255



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 44/199 (22%), Positives = 90/199 (45%), Gaps = 21/199 (10%)

Query: 5   SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTT-------------PP 51
           SS +    + E++T+  G  ++ +  +   +    +AT+  +STT              P
Sbjct: 189 SSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTP 248

Query: 52  TSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASS 111
           +S      NS SS++S+ +    + +S++ SS    +   +S++PS+ +     S ++++
Sbjct: 249 SSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTT 308

Query: 112 HVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVH 171
                     + +    G  A  A  S SS++SS  + AT+      ++S   SS AS  
Sbjct: 309 SSGANTATNSDSSTTSSG--ASTATNSESSTTSSGASTATN------SESSTTSSGASTA 360

Query: 172 HANGLAKSSTTVSSFANSK 190
             +G + +S+  S+  NS+
Sbjct: 361 TNSGSSTTSSGTSTATNSE 379


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 60/202 (29%), Positives = 88/202 (43%), Gaps = 14/202 (6%)

Query: 3    SQSSGSGDGNDDEATTSKDGG-----FSSPSPSAAAAAQEVRSATDGNTSTTPPTS---A 54
            SQS  SG      ATT+   G      S P+P    +      A+ G    +   +   A
Sbjct: 2472 SQSLSSGA----VATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPA 2527

Query: 55   KKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVP 114
            K+R+ +SSSSSSS+SS+      S+SSSS +       S+ P      L   V + +  P
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVAL-KRVPSPTPAP 2586

Query: 115  IQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHAN 174
             ++ +R     E      K    SSSSSSSSS ++++S      + S   SS +S   ++
Sbjct: 2587 -KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645

Query: 175  GLAKSSTTVSSFANSKPGSAKK 196
              + S       A  KP S KK
Sbjct: 2646 SSSPSPAKPGPQALPKPASPKK 2667



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 39/146 (26%), Positives = 54/146 (36%), Gaps = 7/146 (4%)

Query: 6    SGSGDGNDDEATTSKDGGF---SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            SGS  G  D   T   G     SSP P A       RS +  +          +R+ + S
Sbjct: 1460 SGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGS 1519

Query: 63   SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASP-STSSFCLGVSVAASSHVPIQKKLRF 121
             SS    +  R      S S S+  L  + SASP   S         A +  P++++ R 
Sbjct: 1520 ESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRS 1579

Query: 122  EDTLEFVGFDAKMAEESSSSSSSSSP 147
              + E    D+K       S S SSP
Sbjct: 1580 GSSPE---VDSKSRLSPRRSRSGSSP 1602



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 5/99 (5%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNT-STTPPTSAKKRKLNS 61
            S SS  G G   E ++S +     P P +  A +  RS+ +  T S TPP     R    
Sbjct: 1638 SGSSSKGRGPSPEGSSSTESSPEHP-PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPE 1696

Query: 62   SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSS 100
             +  +  S   R    S  + S TP   PR   SPS SS
Sbjct: 1697 LTRKARLSRRSRSASSSPETRSRTP---PRHRRSPSVSS 1732



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 24/87 (27%), Positives = 43/87 (49%)

Query: 10   DGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNS 69
            +G   E T +K    SS S S+++++    S++  ++S++  +S+     +SSSSSS + 
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651

Query: 70   SNEREDFDSTSSSSSTPPLQPRDSASP 96
            +          +S   PP   R S SP
Sbjct: 2652 AKPGPQALPKPASPKKPPPGERRSRSP 2678



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 42/196 (21%), Positives = 72/196 (36%), Gaps = 23/196 (11%)

Query: 6    SGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSS 65
            SGS    D ++  S     S  SP      +    A  G+ S+  P +   R L   S S
Sbjct: 1579 SGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRS 1638

Query: 66   SSNSSNEREDFDSTSSSSSTPPLQP---------RDSASPSTSSFCLGVSVAASSHVPIQ 116
             S+S       + +SS+ S+P   P         R S  P T S       ++ S   + 
Sbjct: 1639 GSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698

Query: 117  KKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGL 176
            +K R                  S S+SSS  T + +  +  ++ S+     A    ++  
Sbjct: 1699 RKARL--------------SRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRR 1744

Query: 177  AKSSTTVSSFANSKPG 192
             +S+++  +   S+ G
Sbjct: 1745 RRSASSPRTKTTSRRG 1760



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 47/186 (25%), Positives = 65/186 (34%), Gaps = 13/186 (6%)

Query: 27  PSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTP 86
           P+P        VR ++   + T      KK+K     S SS+   ER+         S  
Sbjct: 163 PAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES 222

Query: 87  PLQPRDSASPSTSSFCLGVS---VAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSS 143
             + R   SP+  S           + S  P  K  R   +       A  A  S +S S
Sbjct: 223 ESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST-----SADSASSSDTSRS 277

Query: 144 SSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSST--TVSSFANSKPGSAKKLVIKN 201
            S   AA +    L  +S    S AS     G A  S   T S+   S P +A K     
Sbjct: 278 RSRSAAAKTHTTALAGRS---PSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSP 334

Query: 202 FKDKPK 207
           ++DK K
Sbjct: 335 YEDKDK 340



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 35/183 (19%), Positives = 69/183 (37%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            S S+ S   +  ++ T++ G  SSP P   +     R ++  +   T      +R  ++S
Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS 1711

Query: 63   SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122
            SS  + S        S S SS  P  + R S    ++S     + +     P  K    +
Sbjct: 1712 SSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQ 1771

Query: 123  DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 182
             +      +          S SS  T+   Q+ + +++        S +H+   A+  ++
Sbjct: 1772 RSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESS 1831

Query: 183  VSS 185
             +S
Sbjct: 1832 RTS 1834



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 37/140 (26%), Positives = 55/140 (39%), Gaps = 7/140 (5%)

Query: 25  SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 84
           SSP P   +     +S    ++S++P    K        S +S  +NE+       S   
Sbjct: 819 SSPPPKQKSKTPSRQS----HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFE 874

Query: 85  TPPLQPRDSASPSTSSFCLGVSV--AASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSS 142
           + P     S +PS  S C G S     SS  P Q   R       V       + S S S
Sbjct: 875 SSPDPELKSRTPSRHS-CSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS 933

Query: 143 SSSSPTAATSQQQQLKNKSI 162
           SS SP+  TS+    +++S+
Sbjct: 934 SSPSPSRVTSRTTPRRSRSV 953


>gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo
            sapiens]
          Length = 2517

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 69/301 (22%), Positives = 123/301 (40%), Gaps = 72/301 (23%)

Query: 560  AELIAKYVDSKLRAGNKEATDE-----ELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKR 614
            +E  A+Y+D +++ G            +L++ L+ IM++         FE FY+  +A R
Sbjct: 1546 SEQFARYIDQQIQGGLIGGAPGVEMLGQLQRHLEPIMVLSGLELAT-TFEHFYQHYMADR 1604

Query: 615  LLVGKSASVDAEKSMLSKLKHECGAAFTSKL-EGMFKDMELSKDIMIQFKQYM------- 666
            LL   S+ ++        +  + G  F ++L + M + +  S+++  QF  +        
Sbjct: 1605 LLSFGSSWLEGA------VLEQIGLCFPNRLPQLMLQSLSTSEELQRQFHLFQLQRLDKL 1658

Query: 667  ---QNQNVPGNIE-----------------------LTVNILTMGYWPT------YVPME 694
               Q       +E                       +++ +L+   WP       Y P +
Sbjct: 1659 FLEQEDEEEKRLEEEEEEEEEEEAEKELFIEDPSPAISILVLSPRCWPVSPLCYLYHPRK 1718

Query: 695  VHLPPEMVKLQEIFKTFY----------LGKHSGRKLQWQSTLGHCVLKAEFKEGKKELQ 744
              LP E     + F +FY          +G H  R+LQW + LG    +AE + GK+ L 
Sbjct: 1719 C-LPTEFCDALDRFSSFYSQSQNHPVLDMGPH--RRLQW-TWLG----RAELQFGKQILH 1770

Query: 745  VSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIED 804
            VS  Q  +LL FN+ EE S+E + + + +    L + L  L  G   +     +G+D   
Sbjct: 1771 VSTVQMWLLLKFNQTEEVSVETLLKDSDLSPELLLQALVPLTSGNGPLTLH--EGQDFPH 1828

Query: 805  G 805
            G
Sbjct: 1829 G 1829


>gi|40807452 peroxisome proliferator-activated receptor gamma,
            coactivator-related 1 [Homo sapiens]
          Length = 1664

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 46/156 (29%), Positives = 72/156 (46%), Gaps = 13/156 (8%)

Query: 14   DEATTSKDGGFSSP--SPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS------SSSS 65
            D  T+S+    S+P  +PS+  + +      D NT T P  SAK+R +        S+S 
Sbjct: 1355 DHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNTRTPPEPSAKQRSMRCYRKACRSASP 1414

Query: 66   SSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTL 125
            SS     R   +S S SS +       S+S S+SS     S + S   P  K+ R     
Sbjct: 1415 SSQGWQGRRGRNSRSVSSGSNRTSEASSSSSSSSSSSRSRSRSLS---PPHKRWRRSSCS 1471

Query: 126  EFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKS 161
                  ++    SSSSSSSSS ++++S   + +++S
Sbjct: 1472 S--SGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSRS 1505



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 16/134 (11%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPP----------T 52
            S SS    G     + S   G +  S ++++++    S+   + S +PP          +
Sbjct: 1413 SPSSQGWQGRRGRNSRSVSSGSNRTSEASSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSS 1472

Query: 53   SAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSH 112
            S + R+ +SSSSSSS+SS+      S+ S S +P  + R       SS+       +  H
Sbjct: 1473 SGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSRSPSPRRRSDRRRRYSSY------RSHDH 1526

Query: 113  VPIQKKLRFEDTLE 126
               Q+ L+ E  +E
Sbjct: 1527 YQRQRVLQKERAIE 1540


>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
            sapiens]
          Length = 2881

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 44/139 (31%), Positives = 62/139 (44%), Gaps = 29/139 (20%)

Query: 48   TTPPTSAKKR--KLNSSSSSSSNSSNEREDFD--STSSSSSTPPLQPRDSASPSTSSFCL 103
            T  P S K R  K  S SSS S+S +ER      S+SSSSS+     R  +S S+SS C 
Sbjct: 2113 TPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCS 2172

Query: 104  GVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSIL 163
              S ++SS                          SSSSSSSSS  + + +++  K +S  
Sbjct: 2173 SASSSSSS----------------------STSSSSSSSSSSSEESDSDEEEAQKRES-- 2208

Query: 164  ISSVASVHHANGLAKSSTT 182
             ++    +    +A  STT
Sbjct: 2209 -TTHMKAYDEESVASLSTT 2226



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 2/99 (2%)

Query: 4    QSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSS 63
            + S S   +D ++  S     SS S S+++ +     ++  ++S+    S+      SSS
Sbjct: 2126 RGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSS 2185

Query: 64   SSSSNSSNEREDFDSTSSS--SSTPPLQPRDSASPSTSS 100
            SSSS+SS+E  D D   +    ST  ++  D  S ++ S
Sbjct: 2186 SSSSSSSSEESDSDEEEAQKRESTTHMKAYDEESVASLS 2224



 Score = 37.7 bits (86), Expect = 0.049
 Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 4/127 (3%)

Query: 28   SPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPP 87
            +P+ A+    V      ++S +   S +    + SSSSSS+SS       S+SSSSS+  
Sbjct: 2113 TPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCS 2172

Query: 88   LQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSP 147
                 S+S ++SS     S +  S    ++  + E T     +D    EES +S S++  
Sbjct: 2173 SASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMKAYD----EESVASLSTTQD 2228

Query: 148  TAATSQQ 154
                S Q
Sbjct: 2229 ETQDSFQ 2235



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 21/74 (28%), Positives = 38/74 (51%)

Query: 20   KDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDST 79
            K G  SS    + +      S +  ++S++  + ++    +SSSSS S++S+      S+
Sbjct: 2125 KRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSS 2184

Query: 80   SSSSSTPPLQPRDS 93
            SSSSS+   +  DS
Sbjct: 2185 SSSSSSSSSEESDS 2198


>gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial
           [Homo sapiens]
          Length = 909

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 42/185 (22%), Positives = 76/185 (41%), Gaps = 19/185 (10%)

Query: 17  TTSKDGGFSSPSPSAAAAAQEVRS-ATDGNTS---TTPPTSAKKRKLNSSSSSSSNSSNE 72
           TT++    S+PS S++    E  S +T G TS   TT  TS       SS +++  +S++
Sbjct: 172 TTTETPSSSTPSFSSSITTTETTSHSTPGFTSSITTTETTSHSTPSFTSSITTTETTSHD 231

Query: 73  REDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDA 132
              F S+ ++S TP       ++PS++S        + S       +   +T        
Sbjct: 232 TPSFTSSITTSETP-----SHSTPSSTSLITTTKTTSHSTPSFTSSITTTET-------- 278

Query: 133 KMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPG 192
                S+ S +SS  T  T+        S + ++  + H       S TT  + ++S P 
Sbjct: 279 --TSHSAHSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPS 336

Query: 193 SAKKL 197
            +  +
Sbjct: 337 FSSSI 341



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 42/185 (22%), Positives = 72/185 (38%), Gaps = 19/185 (10%)

Query: 15  EATTSKDGGFSSPSPSAAAAAQEVRSATDGNTST------TPP--TSAKKRKLNSSSSSS 66
           E T+     F+S   +    +    S T  NT T      TP   TS    +  SSS+ S
Sbjct: 124 ETTSHSTPSFTSSIRTTETTSYSTPSFTSSNTITETTSHSTPSYITSITTTETPSSSTPS 183

Query: 67  SNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLE 126
            +SS    +  S S+   T  +   ++ S ST SF   ++   ++           DT  
Sbjct: 184 FSSSITTTETTSHSTPGFTSSITTTETTSHSTPSFTSSITTTETTS---------HDTPS 234

Query: 127 FVG--FDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVS 184
           F      ++    S+ SS+S   T  T+        S + ++  + H A+    S TT  
Sbjct: 235 FTSSITTSETPSHSTPSSTSLITTTKTTSHSTPSFTSSITTTETTSHSAHSFTSSITTTE 294

Query: 185 SFANS 189
           + +++
Sbjct: 295 TTSHN 299


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 43/170 (25%), Positives = 68/170 (40%), Gaps = 12/170 (7%)

Query: 3   SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
           S+  G G    +E        F  P  +      E  S   G     PP      K  ++
Sbjct: 230 SRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPAT 289

Query: 63  SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTS--------SFCLGVSVAASSHVP 114
           + S   S+ +++   S+  S S P   PR S+S S S        S   G  V A S   
Sbjct: 290 ADSPKPSAKKQKK-SSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPR 348

Query: 115 IQKK---LRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKS 161
             KK   +   ++ +   F ++ A+ S S+SSSSS +++ S  +  +N S
Sbjct: 349 EAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHS 398



 Score = 37.0 bits (84), Expect = 0.084
 Identities = 36/138 (26%), Positives = 59/138 (42%), Gaps = 18/138 (13%)

Query: 14  DEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNER 73
           D+++T  +   +   P  A  A EV  +   + ++    SA+    NSSSSS S+S ++ 
Sbjct: 332 DKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDF 391

Query: 74  EDFDSTSSS---SSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGF 130
           E   + S     S    LQ  +S    +SS   G   A  ++     +L F D+      
Sbjct: 392 EPSQNHSQGPLRSMVEDLQSEESDEDDSSS---GEEAAGKTNPGRDSRLSFSDS------ 442

Query: 131 DAKMAEESSSSSSSSSPT 148
                 ES +S+ SS P+
Sbjct: 443 ------ESDNSADSSLPS 454


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 47/194 (24%), Positives = 79/194 (40%), Gaps = 25/194 (12%)

Query: 15   EATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNERE 74
            E   + +   S P   +    +    + DG +   PP   K++K ++   S S+SS+ R 
Sbjct: 974  EGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPP---KRKKADTEGKSPSHSSSNRP 1030

Query: 75   DFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQ------------KKLRFE 122
                TS+  S  P     S +P       GV+      + IQ               ++ 
Sbjct: 1031 FTPPTSTGGSKSPGSAGRSQTPP------GVATPPIPKITIQIPKGTVMVGKPSSHSQYT 1084

Query: 123  DTLEFVGFDAKMAEESSSSSSSSSPTAA--TSQQQQLKNKSILISSVASVHHANGLAKSS 180
             +       +K     SSSSSSS+ T+    S + +  + S L SS+ S   ++G ++S 
Sbjct: 1085 SSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSK 1144

Query: 181  TTVSSFANSKPGSA 194
               SS +  KPGS+
Sbjct: 1145 N--SSQSGGKPGSS 1156



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 48/204 (23%), Positives = 76/204 (37%), Gaps = 31/204 (15%)

Query: 8    SGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSS 67
            SG G    + TS   G  S S   ++          G+ S   P S+     +SSS SSS
Sbjct: 1227 SGSGGSHMSGTSSSSGMKSSSGLGSS----------GSLSQKTPPSSNSCTASSSSFSSS 1276

Query: 68   NSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSF-----------------CLGVSVAAS 110
             SS         SS   +P    + S +                        +GVS  +S
Sbjct: 1277 GSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSS 1336

Query: 111  SHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASV 170
            SH P+  K       EF G   K  ++ S  S+S S  +  S ++  ++K++  + VA +
Sbjct: 1337 SH-PMSSKHNMSGG-EFQGKREKSDKDKSKVSTSGS--SVDSSKKTSESKNVGSTGVAKI 1392

Query: 171  HHANGLAKSSTTVSSFANSKPGSA 194
              +     S +  +     KPG +
Sbjct: 1393 IISKHDGGSPSIKAKVTLQKPGES 1416



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 50/206 (24%), Positives = 89/206 (43%), Gaps = 19/206 (9%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSA-TDGNTST--------TPPTS 53
            S S  +  G+   + +      SS S S+A+ + +++S+ ++G++S+        +  +S
Sbjct: 1079 SHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSS 1138

Query: 54   AKKRKLNSSSSSSSNSSNEREDFDSTSSSSST---PPLQPRDSASPSTSSFCLGVSVAAS 110
               +  NSS S     S+       +S SSST   P  +P    +PS S      +++ S
Sbjct: 1139 GSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSK----PNISPS 1194

Query: 111  SHVPIQKKLRFEDTLEFVGF--DAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVA 168
               P     +    ++ V     +  A+   SS S  S  + TS    +K+ S L SS  
Sbjct: 1195 HSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSS-G 1253

Query: 169  SVHHANGLAKSSTTVSSFANSKPGSA 194
            S+      + +S T SS + S  GS+
Sbjct: 1254 SLSQKTPPSSNSCTASSSSFSSSGSS 1279


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 46/197 (23%), Positives = 76/197 (38%), Gaps = 18/197 (9%)

Query: 5   SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64
           SS      D    TS     S+P  S   +   V S+   N STTP  S  +   ++ +S
Sbjct: 431 SSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEAS 490

Query: 65  SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDT 124
           SS  ++       ST S  STP      S  P  SS       +  S  P+       DT
Sbjct: 491 SSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASS-----EASTLSTTPV-------DT 538

Query: 125 LEFVGFDAKMAEESSSSSSSSSPTAATSQ------QQQLKNKSILISSVASVHHANGLAK 178
              V   ++ +  S++   +S PT+  S+         +  + ++ S  ++       + 
Sbjct: 539 STPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSN 598

Query: 179 SSTTVSSFANSKPGSAK 195
           +  T SS A+S   +A+
Sbjct: 599 TFVTTSSEASSSSTTAE 615



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 48/194 (24%), Positives = 84/194 (43%), Gaps = 12/194 (6%)

Query: 3   SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
           S SS + +G     +T  +G  S+P  +   + + V S+    TSTTP  S      N+ 
Sbjct: 549 SSSSTTPEGTSIPTSTPSEG--STPLTNMPVSTRLVVSSEASTTSTTPADS------NTF 600

Query: 63  SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAAS-SHVPIQKKLRF 121
            ++SS +S+     + TS  +ST   +     S S S+  +  S A++ S  P+      
Sbjct: 601 VTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPV 660

Query: 122 EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS- 180
             + E     +    E +S  +S+    +T       N +++ SS AS      +  S+ 
Sbjct: 661 TTSTE--ATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTP 718

Query: 181 TTVSSFANSKPGSA 194
            T S+ A+S P +A
Sbjct: 719 VTTSTEASSSPTTA 732



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 40/193 (20%), Positives = 78/193 (40%), Gaps = 8/193 (4%)

Query: 3   SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
           S S  + +G     +T  +G  S+P  S  A+   V ++     S TP  ++     ++ 
Sbjct: 313 SSSPTTAEGTSIPTSTYTEG--STPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTE 370

Query: 63  SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122
            SS   ++       ST S  STP      +  P ++        + +S +P+  K  F 
Sbjct: 371 PSSLPTTAEATSMLTSTLSEGSTPL-----TNMPVSTILVASSEASTTSTIPVDSK-TFV 424

Query: 123 DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 182
            T          AE++S ++S+ S  +       +    +  S  +++      +K+  T
Sbjct: 425 TTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVT 484

Query: 183 VSSFANSKPGSAK 195
            S+ A+S P +A+
Sbjct: 485 TSTEASSSPPTAE 497



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 39/193 (20%), Positives = 81/193 (41%), Gaps = 8/193 (4%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            S SS + DG     +T  +G  S+P  S   + + V S+ + +T +T P         S+
Sbjct: 1080 SSSSTTADGTSMPTSTYSEG--STPLTSVPVSTRLVVSS-EASTLSTTPVDTSIPVTTST 1136

Query: 63   SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122
             +SSS ++ E     ++  S  T PL    ++ P +++  +       S  P+  K +  
Sbjct: 1137 EASSSPTTAEGTSIPTSPPSEGTTPL----ASMPVSTTLVVSSEANTLSTTPVDSKTQVA 1192

Query: 123  DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 182
             + E        AE +S  +S+    +       +++  +  S  +++  +     +  T
Sbjct: 1193 TSTE-ASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVT 1251

Query: 183  VSSFANSKPGSAK 195
             S+  +S P +A+
Sbjct: 1252 TSAETSSSPTTAE 1264



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 47/200 (23%), Positives = 84/200 (42%), Gaps = 20/200 (10%)

Query: 2    MSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61
            +S S+ S +G     +T  +G  S+P  S   + + + S+     STTP  ++     ++
Sbjct: 2552 ISSSATSAEGTSMPTSTYSEG--STPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTST 2609

Query: 62   SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121
             +SSS  ++ +     ST S  ST       S  P  SS       +  S  P+      
Sbjct: 2610 ETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASS-----EASTLSTTPV------ 2658

Query: 122  EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQ-----LKNKSILISSVASVHHANGL 176
             DT   V      +   +++  SS PT+   ++       L + ++L +S AS      +
Sbjct: 2659 -DTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPV 2717

Query: 177  AKSS-TTVSSFANSKPGSAK 195
              S+  T S+ A+S P +A+
Sbjct: 2718 DTSTPVTTSAEASSSPTTAE 2737



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 43/196 (21%), Positives = 75/196 (38%), Gaps = 8/196 (4%)

Query: 5    SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64
            SS           TS  G  S+P  +   +   + ++     STTP  ++     ++ +S
Sbjct: 2671 SSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEAS 2730

Query: 65   SSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVS-VAASSHVPIQKKLRFED 123
            SS  ++       ST S  STP      S  P  SS    VS  A  + +P+        
Sbjct: 2731 SSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPV-------T 2783

Query: 124  TLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTV 183
            T          AE +S  +S+ S T+       + +  +  S   ++        +  T 
Sbjct: 2784 TSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTT 2843

Query: 184  SSFANSKPGSAKKLVI 199
            S+ A+S P +A+ +V+
Sbjct: 2844 STKASSSPTTAEGIVV 2859



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 47/200 (23%), Positives = 86/200 (43%), Gaps = 30/200 (15%)

Query: 17   TTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTT----PPTSAKKRKLNSSSSSSSNSSNE 72
            TTS +   SSP P+A   +    + ++G+T  T      T     + ++ S++ +++S  
Sbjct: 1015 TTSTEA--SSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTP 1072

Query: 73   REDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE---DTLEFVG 129
               +   SSSS+T      D  S  TS++  G +   S  VP+  +L       TL    
Sbjct: 1073 VTTYSQASSSSTT-----ADGTSMPTSTYSEGSTPLTS--VPVSTRLVVSSEASTLSTTP 1125

Query: 130  FDAKMAEESSSSSSSSSPTA-------------ATSQQQQLKNKSILISSVASVHHANGL 176
             D  +   +S+ +SSS  TA              T       + ++++SS A+      +
Sbjct: 1126 VDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPV 1185

Query: 177  -AKSSTTVSSFANSKPGSAK 195
             +K+    S+ A+S P +A+
Sbjct: 1186 DSKTQVATSTEASSPPPTAE 1205



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 45/193 (23%), Positives = 73/193 (37%), Gaps = 8/193 (4%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            S S  + +G     +T  +G  S+P  S   +   V S+     STTP  ++      S 
Sbjct: 3260 SSSPPTAEGTSMPTSTPSEG--STPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQ 3317

Query: 63   SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122
            +SSS   ++      ST S  STP      S +P  SS       +  S  P+       
Sbjct: 3318 ASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSS-----EASTLSTTPVDTSTPVT 3372

Query: 123  DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 182
             + E        AE +S  +SS S          +    ++ S V ++      + +  T
Sbjct: 3373 TSTE-ASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVT 3431

Query: 183  VSSFANSKPGSAK 195
             S+ A+S P  A+
Sbjct: 3432 TSTEASSSPTIAE 3444



 Score = 37.4 bits (85), Expect = 0.064
 Identities = 45/209 (21%), Positives = 81/209 (38%), Gaps = 40/209 (19%)

Query: 17   TTSKDGGFSSPSPSAAAAAQEVRSATDGNT--------------------STTPPTSAKK 56
            TTS +   SSP P+A   +    ++++GNT                    STTP  ++  
Sbjct: 2311 TTSTEA--SSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTP 2368

Query: 57   RKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQ 116
                S + SS  ++++     ST S  STP      S  P  SS       +  S  P+ 
Sbjct: 2369 VTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSS-----EASTHSTTPV- 2422

Query: 117  KKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQ------QQQLKNKSILISSVASV 170
                  DT   V    + +   +++  +S PT+  S+         +    ++ S   ++
Sbjct: 2423 ------DTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTL 2476

Query: 171  HHANGLAKSSTTVSSFANSKPGSAKKLVI 199
                    +  T S+ A+S P +A+ +V+
Sbjct: 2477 STTPVDTSTPMTTSTEASSSPTTAEDIVV 2505



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 21/72 (29%), Positives = 38/72 (52%)

Query: 27   PSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTP 86
            PS    ++  +V  AT G  ST   TS +    ++SSSS++ S +  ++F + + +++ P
Sbjct: 3942 PSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAP 4001

Query: 87   PLQPRDSASPST 98
                  S +PST
Sbjct: 4002 LTYVTMSTAPST 4013



 Score = 34.3 bits (77), Expect = 0.54
 Identities = 39/178 (21%), Positives = 72/178 (40%), Gaps = 13/178 (7%)

Query: 37  EVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASP 96
           E+ S     TS TP  S+ +     S ++S ++S+    F S++  +S+P          
Sbjct: 90  EMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPM 149

Query: 97  ST-SSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQ 155
           ST S   +  ++A  S  P+     +      V     +   + +SSS ++P + T  + 
Sbjct: 150 STPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKS 209

Query: 156 QLKNKSILISS-------VASVHHANGLA-----KSSTTVSSFANSKPGSAKKLVIKN 201
                S  ++S       VAS      L       +  T+S+ A+S P +A+   + N
Sbjct: 210 TNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSN 267



 Score = 34.3 bits (77), Expect = 0.54
 Identities = 47/191 (24%), Positives = 75/191 (39%), Gaps = 29/191 (15%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            S S    +G     +T+ +G  S+P      +   V S+     STTP  ++     +S 
Sbjct: 3437 SSSPTIAEGTSLPTSTTSEG--STPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSP 3494

Query: 63   SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122
            ++SS  ++       ST+   STP      S +P  SS       +  S  P+       
Sbjct: 3495 TNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASS-----EASTLSTTPV------- 3542

Query: 123  DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 182
            D+  FV         +SSS +SSSP        ++   S   SS+ +      +  SST 
Sbjct: 3543 DSNTFV---------TSSSQASSSPATLQVTTMRMSTPSEGSSSLTT------MLLSSTY 3587

Query: 183  VSSFANSKPGS 193
            V+S   S P +
Sbjct: 3588 VTSSEASTPST 3598



 Score = 33.5 bits (75), Expect = 0.93
 Identities = 38/165 (23%), Positives = 62/165 (37%), Gaps = 6/165 (3%)

Query: 25  SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 84
           S+P  +   +   V S+    TST P  S       S +SSS  ++ +     ST S  S
Sbjct: 392 STPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGS 451

Query: 85  TPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSS 144
           TP      S +P  SS    +S       P+  K +   + E        AE +S  +S+
Sbjct: 452 TPLTSMPVSTTPVASSEASNLST-----TPVDSKTQVTTSTE-ASSSPPTAEVNSMPTST 505

Query: 145 SSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANS 189
            S  +       +    +  S  +++        +  T SS A+S
Sbjct: 506 PSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASS 550



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 21/115 (18%)

Query: 41   ATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSS 100
            +++GNT +T P  +K +  NS+ +SSS ++      + +S + S P        SP  +S
Sbjct: 2058 SSEGNTLSTTPVDSKTQVTNSTEASSSATA------EGSSMTISAP-----SEGSPLLTS 2106

Query: 101  FCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSS-SSSSSPTAATSQQ 154
              L  +  AS             TL     D+     +S+  SSS  PT  TS Q
Sbjct: 2107 IPLSTTPVASPEA---------STLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQ 2152



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 38/165 (23%), Positives = 66/165 (40%), Gaps = 16/165 (9%)

Query: 2    MSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61
            +S S    +G     +T  +G  S+   S   +   V S+   + STTP  ++      S
Sbjct: 1492 VSSSPTPAEGTSIAISTPSEG--STALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYS 1549

Query: 62   SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121
             +SSS  +++      ST S  STP      ++ P ++   +       S  PI  K + 
Sbjct: 1550 QASSSPTTADGTSMQTSTYSEGSTPL-----TSLPVSTMLVVSSEANTLSTTPIDSKTQV 1604

Query: 122  EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISS 166
              + E           SS+++  SS T +T  +      SI +S+
Sbjct: 1605 TASTE---------ASSSTTAEGSSMTISTPSEGSPLLTSIPVST 1640



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 45/198 (22%), Positives = 81/198 (40%), Gaps = 18/198 (9%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            + S  + +G     +T  +G  ++P  S   +   V ++     STTP  S      ++ 
Sbjct: 2258 TSSPTTAEGTSIPTSTLSEG--TTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTE 2315

Query: 63   SSSSSNSSNEREDFDSTSSSSSTP----PLQPRDSASPSTSSFCLGVSVAASSHVPIQKK 118
            +SS   ++       STSS  +TP    P+     AS  TS+     +  A +  P+   
Sbjct: 2316 ASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLS---TTPADTSTPV--- 2369

Query: 119  LRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAK 178
                 T    G     A+++S  +S+ S  +       +    + +SS AS H    +  
Sbjct: 2370 ----TTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPV-VSSEASTHSTTPVDT 2424

Query: 179  SS-TTVSSFANSKPGSAK 195
            S+  T S+ A+S P +A+
Sbjct: 2425 STPVTTSTEASSSPTTAE 2442



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 38/151 (25%), Positives = 58/151 (38%), Gaps = 14/151 (9%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            S S  + +G     +T  +G  S+P  S   +   V        STTP  S      ++ 
Sbjct: 3025 SSSPTTAEGTGIPISTPSEG--STPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTE 3082

Query: 63   SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122
             SSS   +       ST S  STP      S +P TSS     +++  S  P+       
Sbjct: 3083 VSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSS-----AISTLSTTPV------- 3130

Query: 123  DTLEFVGFDAKMAEESSSSSSSSSPTAATSQ 153
            DT   V    +     ++S  +S PT+  S+
Sbjct: 3131 DTSTPVTTSTEAHSSPTTSEGTSMPTSTPSE 3161



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 41/183 (22%), Positives = 72/183 (39%), Gaps = 17/183 (9%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            S S  + DG         +G  S+P  S   +   V S+     STTP  ++     ++ 
Sbjct: 1964 SSSPTTADGTSMPTPAYSEG--STPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTE 2021

Query: 63   SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122
             SSS  ++       ST S  +TP      +  P +++  +       S  P+  K +  
Sbjct: 2022 GSSSPTTAGGTSIQTSTPSERTTPL-----AGMPVSTTLVVSSEGNTLSTTPVDSKTQVT 2076

Query: 123  DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTT 182
            ++ E        A  S+++  SS   +A S+   L     L ++  +   A+ L  S+T 
Sbjct: 2077 NSTE--------ASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTL--STTP 2126

Query: 183  VSS 185
            V S
Sbjct: 2127 VDS 2129



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 51/214 (23%), Positives = 83/214 (38%), Gaps = 19/214 (8%)

Query: 3    SQSSGSGDGNDDEAT-TSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61
            SQ+  S    DD +  TS     S+P  S   +   V S+     STTP  ++     ++
Sbjct: 2373 SQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTST 2432

Query: 62   SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVA-ASSHVPIQKKLR 120
             +SSS  ++       S  S  +TP      S +P  SS    +S     +  P+     
Sbjct: 2433 EASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTE 2492

Query: 121  FED---TLEFVGFDAKMAEESS--------SSSSSSSPTAATSQQQQLKNKSILISSV-- 167
                  T E +      A E S        S++  +SP A+T     + + S +++S   
Sbjct: 2493 ASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEI 2552

Query: 168  -ASVHHANGLAKSSTTVSSFA---NSKPGSAKKL 197
             +S   A G +  ++T S  +    S P S K L
Sbjct: 2553 SSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPL 2586



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 42/200 (21%), Positives = 77/200 (38%), Gaps = 20/200 (10%)

Query: 2    MSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61
            +S S    +G     +T  +G   +P  S   +   V ++     STTP  ++     ++
Sbjct: 843  VSSSPTPAEGTSMPTSTYSEG--RTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNST 900

Query: 62   SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121
             + SS  +S       ST    STP     DS +P  SS          S  P+      
Sbjct: 901  EARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSS-----EARTLSATPV------ 949

Query: 122  EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGL----- 176
             DT   V    +     +++  +S PT+  S+       + +  ++ +   A+ L     
Sbjct: 950  -DTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPV 1008

Query: 177  -AKSSTTVSSFANSKPGSAK 195
             + +  T S+ A+S P +A+
Sbjct: 1009 DSNTPLTTSTEASSPPPTAE 1028



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 43/179 (24%), Positives = 70/179 (39%), Gaps = 25/179 (13%)

Query: 32   AAAAQEVRSAT--DGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPL- 88
            A++A  + S T  D +T  T  T A      S  +S  NS+        TS   ST P+ 
Sbjct: 1350 ASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVV 1409

Query: 89   ---------QPRDSASPSTSS--FCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEE 137
                      P D+++P T+S       + A    +P       +  L+ +         
Sbjct: 1410 SSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVAN 1469

Query: 138  SSSSSSSSSP----------TAATSQQQQLKNKSILISSVASVHHA-NGLAKSSTTVSS 185
            S +S+ S++P          TA +S     +  SI IS+ +    A   +  S+TTV+S
Sbjct: 1470 SEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVAS 1528



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 35/199 (17%), Positives = 80/199 (40%), Gaps = 20/199 (10%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            + SS + +G+    +   +G   SP  ++   +    ++ + +T +T P  +    + S+
Sbjct: 2081 ASSSATAEGSSMTISAPSEG---SPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITST 2137

Query: 63   SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122
              SSS    E     +++ S    PL    ++ P +++     +++  S  P+       
Sbjct: 2138 EVSSSPIPTEGTSMQTSTYSDRRTPL----TSMPVSTTVVASSAISTLSTTPV------- 2186

Query: 123  DTLEFVGFDAKMAEESSSSSSSSSPTAATSQ------QQQLKNKSILISSVASVHHANGL 176
            DT   V    +     ++S  +S PT+  S+         +    ++ S  +++      
Sbjct: 2187 DTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVD 2246

Query: 177  AKSSTTVSSFANSKPGSAK 195
              +  T S+ A S P +A+
Sbjct: 2247 TSTPVTTSTEATSSPTTAE 2265



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 39/198 (19%), Positives = 81/198 (40%), Gaps = 10/198 (5%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            S S  + +G     +T+ +G   S   ++   +  + ++ + +T  T P   K   + S+
Sbjct: 1257 SSSPTTAEGTSLPTSTTSEG---STLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSN 1313

Query: 63   SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFE 122
              SSS +  E     +++ S    PL    ++ P  ++     +++  S  P+       
Sbjct: 1314 EVSSSPTPAEGTSMPTSTYSEGRTPL----TSIPVNTTLVASSAISILSTTPVDNSTPVT 1369

Query: 123  DTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSST- 181
             + E     +    E +S  +S+     T       + + ++SS AS   A  +  S+  
Sbjct: 1370 TSTE--ACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPG 1427

Query: 182  TVSSFANSKPGSAKKLVI 199
            T S+ A S P +A+ + I
Sbjct: 1428 TTSAEATSSPTTAEGISI 1445



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 45/200 (22%), Positives = 78/200 (39%), Gaps = 20/200 (10%)

Query: 2    MSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61
            +S S    +G     +T  +G   +P  S       V S+     STTP  ++     ++
Sbjct: 1668 VSSSPTPAEGTSMPTSTYTEG--RTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTST 1725

Query: 62   SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121
             + SS  +S      +ST S  +TP      S +P  SS       +  S  PI      
Sbjct: 1726 EARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSS-----EASTLSATPI------ 1774

Query: 122  EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQ-----QQQLKNKSILISSVASVHHANGL 176
             DT   V    +     +++  +S PT+  S+          + +++ +S AS      +
Sbjct: 1775 -DTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPV 1833

Query: 177  AKSSTTVSSFA-NSKPGSAK 195
              +S  V+S A +S P  A+
Sbjct: 1834 DSNSPVVTSTAVSSSPTPAE 1853



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 37/154 (24%), Positives = 58/154 (37%), Gaps = 23/154 (14%)

Query: 17   TTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDF 76
            +T+ +G  S+   S   +   V S      STTP  S      ++  SSS+ S+      
Sbjct: 2508 STASEG--STLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMP 2565

Query: 77   DSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAE 136
             ST S  STP      S  P  SS       +  S  P+   +                 
Sbjct: 2566 TSTYSEGSTPLRSMPVSTKPLASS-----EASTLSTTPVDTSI----------------P 2604

Query: 137  ESSSSSSSSSPTAATSQQQQLKNKSILISSVASV 170
             ++S+ +SSSPT A      +   S + +S+ S+
Sbjct: 2605 VTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSI 2638



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 41/195 (21%), Positives = 74/195 (37%), Gaps = 16/195 (8%)

Query: 5    SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSS 64
            SS + +G     +T  +G   +P  S   +   V S+     STTP  S      ++ +S
Sbjct: 3203 SSTTAEGTSIPTSTPSEG--MTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEAS 3260

Query: 65   SSSNSSNEREDFDSTSSSSSTP----PLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLR 120
            SS  ++       ST S  STP    P+     AS  TS+     +  A +  P+     
Sbjct: 3261 SSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLS---TTPADTSTPV----- 3312

Query: 121  FEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSS 180
               T         +A+ +S  +S+ S  +            ++ S  +++        + 
Sbjct: 3313 --TTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTP 3370

Query: 181  TTVSSFANSKPGSAK 195
             T S+ A+  P +A+
Sbjct: 3371 VTTSTEASLSPTTAE 3385



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 43/198 (21%), Positives = 86/198 (43%), Gaps = 18/198 (9%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            + SS + +G+    +T  +G   SP  ++   +    ++ + +T +T P  +    + S+
Sbjct: 1610 ASSSTTAEGSSMTISTPSEG---SPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITST 1666

Query: 63   SSSSSNSSNEREDF-DSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121
              SSS +  E      ST +   TP        +P  SS     +++  S  P+      
Sbjct: 1667 EVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASS-----AISTLSTTPVDNSTPV 1721

Query: 122  EDTLEFVGFDAKMAEESSSSSS--SSSPTAATSQQQQLK-NKSILISSVASVHHANGLAK 178
              + E     A+ +  +S  +S  +S+P+  T+    +  + + ++SS AS   A  +  
Sbjct: 1722 TTSTE-----ARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDT 1776

Query: 179  SS-TTVSSFANSKPGSAK 195
            S+  T S+ A S P +A+
Sbjct: 1777 STPVTTSTEATSSPTTAE 1794



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 48/205 (23%), Positives = 85/205 (41%), Gaps = 32/205 (15%)

Query: 3    SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
            S S  + +G     +T+ +G  S+   S   +   V S+     STTP            
Sbjct: 2848 SSSPTTAEGIVVPISTASEG--STLLTSIPVSTTPVASSEASTLSTTP----------VD 2895

Query: 63   SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAAS-----SHVPIQK 117
            +S    +S E     +T+  +S P   P + ++P TS     V VA S     S  P+  
Sbjct: 2896 TSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPV-- 2953

Query: 118  KLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQ-QLKNKSILISSVASVHHANGL 176
                 DT   V   A+ +   +++  +S P +   +++  L + S+    VAS   A+ L
Sbjct: 2954 -----DTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVAS-SEASTL 3007

Query: 177  AK------SSTTVSSFANSKPGSAK 195
            ++      +  T S+ A+S P +A+
Sbjct: 3008 SRTPADTSTPVTTSTEASSSPTTAE 3032



 Score = 30.4 bits (67), Expect = 7.9
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 2/98 (2%)

Query: 3   SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
           + SS + +G     +T  +G  S+P  S       V S+     STTP  ++     ++ 
Sbjct: 667 TSSSTTAEGTSMPTSTYTEG--STPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTE 724

Query: 63  SSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSS 100
           +SSS  +++      ST S  STP      S +  TSS
Sbjct: 725 ASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSS 762



 Score = 30.4 bits (67), Expect = 7.9
 Identities = 40/200 (20%), Positives = 76/200 (38%), Gaps = 21/200 (10%)

Query: 2    MSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61
            +S S    +G     +T  +G  S+P      +   V S+     STTP  ++     ++
Sbjct: 3083 VSSSPTPAEGTSMPISTYSEG--STPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTST 3140

Query: 62   SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRF 121
             + SS  +S       ST S  STP      +  P ++   +    +  S  P+      
Sbjct: 3141 EAHSSPTTSEGTSMPTSTPSEGSTPL-----TYMPVSTMLVVSSEDSTLSATPVDTSTPV 3195

Query: 122  EDTLEFVGFDAKMAEESSSSSSSSSPTAATSQ------QQQLKNKSILISSVASVHHANG 175
              + E        A  S+++  +S PT+  S+         + N  +  S  + +     
Sbjct: 3196 TTSTE--------ATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPV 3247

Query: 176  LAKSSTTVSSFANSKPGSAK 195
             + +  T S+ A+S P +A+
Sbjct: 3248 DSNTPLTTSTEASSSPPTAE 3267


>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
          Length = 717

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 26/75 (34%), Positives = 40/75 (53%)

Query: 26  SPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSST 85
           S + + + +    R+ T  + S +  +S+      SSSS SS+SS       S+SSSSST
Sbjct: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613

Query: 86  PPLQPRDSASPSTSS 100
                RDS+S ++SS
Sbjct: 614 SGSSSRDSSSSTSSS 628



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 25/68 (36%), Positives = 45/68 (66%), Gaps = 6/68 (8%)

Query: 18  TSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFD 77
           TSK    SS S S+++++    S++ G++S++  +S++    +SSSSSS++ S+ R+   
Sbjct: 570 TSKSRSRSSSSSSSSSSST---SSSSGSSSSSGSSSSRS---SSSSSSSTSGSSSRDSSS 623

Query: 78  STSSSSST 85
           STSSSS +
Sbjct: 624 STSSSSES 631



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 9/71 (12%)

Query: 3   SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
           S+S  S   +   ++TS   G SS S S         S++  ++S++  TS    + +SS
Sbjct: 573 SRSRSSSSSSSSSSSTSSSSGSSSSSGS---------SSSRSSSSSSSSTSGSSSRDSSS 623

Query: 63  SSSSSNSSNER 73
           S+SSS+ S  R
Sbjct: 624 STSSSSESRSR 634



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 21/56 (37%), Positives = 30/56 (53%)

Query: 56  KRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASS 111
           K +  SSSSSSS+SS+      S+SSS S+       S+S ++ S     S + SS
Sbjct: 572 KSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSS 627



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 23/64 (35%), Positives = 31/64 (48%)

Query: 37  EVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASP 96
           E +S T   + +      K  K  S SSSSS+SS+      S SSSSS        S+S 
Sbjct: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610

Query: 97  STSS 100
           S++S
Sbjct: 611 SSTS 614



 Score = 30.4 bits (67), Expect = 7.9
 Identities = 43/195 (22%), Positives = 75/195 (38%), Gaps = 29/195 (14%)

Query: 14  DEATTSKDGGFSSPSPSAAAAAQ-------EVRSATDGNTSTTPPTSAKKRKLN------ 60
           ++ +  K+   S P P   A  Q       +++S +     + PP+  +   L       
Sbjct: 455 EKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTP 514

Query: 61  SSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLR 120
             +    +   ER+DF   S   +  P++P  +  P + S        + S    + K  
Sbjct: 515 QVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKS---KTKTRSRSRGRARNKT- 570

Query: 121 FEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAK-- 178
                         +  SSSSSSSSS T+++S        S   SS +S    +G +   
Sbjct: 571 ----------SKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRD 620

Query: 179 SSTTVSSFANSKPGS 193
           SS++ SS + S+  S
Sbjct: 621 SSSSTSSSSESRSRS 635


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 79/353 (22%), Positives = 141/353 (39%), Gaps = 58/353 (16%)

Query: 336  IISDQKVQNKTIDGILLLIERERNG--EAIDRSL---------LRSLLSMLSD----LQI 380
            ++ ++  Q   +   L  +E ERN   + +D  +         + +L   LSD    LQ 
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382

Query: 381  YQDSFEQRFLEETNRLYAAEGQKLMQEREVP----EYLHHVNKRLEEEADRLITYLDQTT 436
            +  + E   LEE  + +  E + L Q+ E      + L     RL++E D L+  LD   
Sbjct: 1383 FASTVEA--LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-- 1438

Query: 437  QKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLY-QLFSRVRGGVQVLLQQWI 495
            Q+ L++ +EK+          Q+  + LL E +  ++S  Y     R     +    + +
Sbjct: 1439 QRQLVSNLEKK----------QRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKAL 1486

Query: 496  EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 555
               +A    +    E ++T      + +D V    D+   KN   +   K A ET + + 
Sbjct: 1487 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEM 1544

Query: 556  PNKPAEL---IAKYVDSKLRAG-NKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDL 611
              +  EL   +    D+KLR   N +A   + E+ L            +D      ++ L
Sbjct: 1545 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ----------ARDEQNEEKRRQL 1594

Query: 612  AKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQ 664
             ++L   ++   D  K      +    AA   KLEG  KD+EL  D  I+ ++
Sbjct: 1595 QRQLHEYETELEDERK------QRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 58/250 (23%), Positives = 109/250 (43%), Gaps = 30/250 (12%)

Query: 355  ERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLM---QEREVP 411
            ER++  E    + L+ L    S L   ++  +++   ET     AE  ++    +++E+ 
Sbjct: 866  ERQQKAE----NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 921

Query: 412  EYLHHVNKRLEEEADR-LITYLDQTTQKSLIATVEKQLLGEHLTAILQK-GLNNLLDENR 469
            E LH +  RLEEE DR      ++      +  +E+QL  E   A  QK  L  +  E +
Sbjct: 922  EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAARQKLQLEKVTAEAK 979

Query: 470  IQDLS---LLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKV 526
            I+ L    L+    +      + LL++ I       S +  N  +++   + L   K+K 
Sbjct: 980  IKKLEDEILVMDDQNNKLSKERKLLEERI-------SDLTTNLAEEEEKAKNLTKLKNKH 1032

Query: 527  DHII---DICFLKNEKF---INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATD 580
            + +I   ++   K EK    +  +K   E   +    + A+L A+  + K++   KE   
Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE--- 1089

Query: 581  EELEKMLDKI 590
            EEL+  L ++
Sbjct: 1090 EELQAALARL 1099


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 79/353 (22%), Positives = 141/353 (39%), Gaps = 58/353 (16%)

Query: 336  IISDQKVQNKTIDGILLLIERERNG--EAIDRSL---------LRSLLSMLSD----LQI 380
            ++ ++  Q   +   L  +E ERN   + +D  +         + +L   LSD    LQ 
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389

Query: 381  YQDSFEQRFLEETNRLYAAEGQKLMQEREVP----EYLHHVNKRLEEEADRLITYLDQTT 436
            +  + E   LEE  + +  E + L Q+ E      + L     RL++E D L+  LD   
Sbjct: 1390 FASTVEA--LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-- 1445

Query: 437  QKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLY-QLFSRVRGGVQVLLQQWI 495
            Q+ L++ +EK+          Q+  + LL E +  ++S  Y     R     +    + +
Sbjct: 1446 QRQLVSNLEKK----------QRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKAL 1493

Query: 496  EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 555
               +A    +    E ++T      + +D V    D+   KN   +   K A ET + + 
Sbjct: 1494 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEM 1551

Query: 556  PNKPAEL---IAKYVDSKLRAG-NKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDL 611
              +  EL   +    D+KLR   N +A   + E+ L            +D      ++ L
Sbjct: 1552 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ----------ARDEQNEEKRRQL 1601

Query: 612  AKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQ 664
             ++L   ++   D  K      +    AA   KLEG  KD+EL  D  I+ ++
Sbjct: 1602 QRQLHEYETELEDERK------QRALAAAAKKKLEGDLKDLELQADSAIKGRE 1648



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 58/250 (23%), Positives = 109/250 (43%), Gaps = 30/250 (12%)

Query: 355  ERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLM---QEREVP 411
            ER++  E    + L+ L    S L   ++  +++   ET     AE  ++    +++E+ 
Sbjct: 873  ERQQKAE----NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 928

Query: 412  EYLHHVNKRLEEEADR-LITYLDQTTQKSLIATVEKQLLGEHLTAILQK-GLNNLLDENR 469
            E LH +  RLEEE DR      ++      +  +E+QL  E   A  QK  L  +  E +
Sbjct: 929  EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAARQKLQLEKVTAEAK 986

Query: 470  IQDLS---LLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKV 526
            I+ L    L+    +      + LL++ I       S +  N  +++   + L   K+K 
Sbjct: 987  IKKLEDEILVMDDQNNKLSKERKLLEERI-------SDLTTNLAEEEEKAKNLTKLKNKH 1039

Query: 527  DHII---DICFLKNEKF---INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATD 580
            + +I   ++   K EK    +  +K   E   +    + A+L A+  + K++   KE   
Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE--- 1096

Query: 581  EELEKMLDKI 590
            EEL+  L ++
Sbjct: 1097 EELQAALARL 1106


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 79/353 (22%), Positives = 141/353 (39%), Gaps = 58/353 (16%)

Query: 336  IISDQKVQNKTIDGILLLIERERNG--EAIDRSL---------LRSLLSMLSD----LQI 380
            ++ ++  Q   +   L  +E ERN   + +D  +         + +L   LSD    LQ 
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389

Query: 381  YQDSFEQRFLEETNRLYAAEGQKLMQEREVP----EYLHHVNKRLEEEADRLITYLDQTT 436
            +  + E   LEE  + +  E + L Q+ E      + L     RL++E D L+  LD   
Sbjct: 1390 FASTVEA--LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-- 1445

Query: 437  QKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLY-QLFSRVRGGVQVLLQQWI 495
            Q+ L++ +EK+          Q+  + LL E +  ++S  Y     R     +    + +
Sbjct: 1446 QRQLVSNLEKK----------QRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKAL 1493

Query: 496  EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 555
               +A    +    E ++T      + +D V    D+   KN   +   K A ET + + 
Sbjct: 1494 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEM 1551

Query: 556  PNKPAEL---IAKYVDSKLRAG-NKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDL 611
              +  EL   +    D+KLR   N +A   + E+ L            +D      ++ L
Sbjct: 1552 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ----------ARDEQNEEKRRQL 1601

Query: 612  AKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQ 664
             ++L   ++   D  K      +    AA   KLEG  KD+EL  D  I+ ++
Sbjct: 1602 QRQLHEYETELEDERK------QRALAAAAKKKLEGDLKDLELQADSAIKGRE 1648



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 58/250 (23%), Positives = 109/250 (43%), Gaps = 30/250 (12%)

Query: 355  ERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLM---QEREVP 411
            ER++  E    + L+ L    S L   ++  +++   ET     AE  ++    +++E+ 
Sbjct: 873  ERQQKAE----NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 928

Query: 412  EYLHHVNKRLEEEADR-LITYLDQTTQKSLIATVEKQLLGEHLTAILQK-GLNNLLDENR 469
            E LH +  RLEEE DR      ++      +  +E+QL  E   A  QK  L  +  E +
Sbjct: 929  EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAARQKLQLEKVTAEAK 986

Query: 470  IQDLS---LLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKV 526
            I+ L    L+    +      + LL++ I       S +  N  +++   + L   K+K 
Sbjct: 987  IKKLEDEILVMDDQNNKLSKERKLLEERI-------SDLTTNLAEEEEKAKNLTKLKNKH 1039

Query: 527  DHII---DICFLKNEKF---INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATD 580
            + +I   ++   K EK    +  +K   E   +    + A+L A+  + K++   KE   
Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE--- 1096

Query: 581  EELEKMLDKI 590
            EEL+  L ++
Sbjct: 1097 EELQAALARL 1106


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 79/353 (22%), Positives = 141/353 (39%), Gaps = 58/353 (16%)

Query: 336  IISDQKVQNKTIDGILLLIERERNG--EAIDRSL---------LRSLLSMLSD----LQI 380
            ++ ++  Q   +   L  +E ERN   + +D  +         + +L   LSD    LQ 
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382

Query: 381  YQDSFEQRFLEETNRLYAAEGQKLMQEREVP----EYLHHVNKRLEEEADRLITYLDQTT 436
            +  + E   LEE  + +  E + L Q+ E      + L     RL++E D L+  LD   
Sbjct: 1383 FASTVEA--LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-- 1438

Query: 437  QKSLIATVEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLY-QLFSRVRGGVQVLLQQWI 495
            Q+ L++ +EK+          Q+  + LL E +  ++S  Y     R     +    + +
Sbjct: 1439 QRQLVSNLEKK----------QRKFDQLLAEEK--NISSKYADERDRAEAEAREKETKAL 1486

Query: 496  EYIKAFGSTIVINPEKDKTMVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR 555
               +A    +    E ++T      + +D V    D+   KN   +   K A ET + + 
Sbjct: 1487 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG--KNVHELEKSKRALETQMEEM 1544

Query: 556  PNKPAEL---IAKYVDSKLRAG-NKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDL 611
              +  EL   +    D+KLR   N +A   + E+ L            +D      ++ L
Sbjct: 1545 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ----------ARDEQNEEKRRQL 1594

Query: 612  AKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDMELSKDIMIQFKQ 664
             ++L   ++   D  K      +    AA   KLEG  KD+EL  D  I+ ++
Sbjct: 1595 QRQLHEYETELEDERK------QRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 58/250 (23%), Positives = 109/250 (43%), Gaps = 30/250 (12%)

Query: 355  ERERNGEAIDRSLLRSLLSMLSDLQIYQDSFEQRFLEETNRLYAAEGQKLM---QEREVP 411
            ER++  E    + L+ L    S L   ++  +++   ET     AE  ++    +++E+ 
Sbjct: 866  ERQQKAE----NELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 921

Query: 412  EYLHHVNKRLEEEADR-LITYLDQTTQKSLIATVEKQLLGEHLTAILQK-GLNNLLDENR 469
            E LH +  RLEEE DR      ++      +  +E+QL  E   A  QK  L  +  E +
Sbjct: 922  EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL--EEEEAARQKLQLEKVTAEAK 979

Query: 470  IQDLS---LLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKTMVQELLDFKDKV 526
            I+ L    L+    +      + LL++ I       S +  N  +++   + L   K+K 
Sbjct: 980  IKKLEDEILVMDDQNNKLSKERKLLEERI-------SDLTTNLAEEEEKAKNLTKLKNKH 1032

Query: 527  DHII---DICFLKNEKF---INAMKEAFETFINKRPNKPAELIAKYVDSKLRAGNKEATD 580
            + +I   ++   K EK    +  +K   E   +    + A+L A+  + K++   KE   
Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE--- 1089

Query: 581  EELEKMLDKI 590
            EEL+  L ++
Sbjct: 1090 EELQAALARL 1099


>gi|34452681 ring finger protein 10 [Homo sapiens]
          Length = 811

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 3/100 (3%)

Query: 2   MSQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNS 61
           M ++SGS   N   A++    G   P  ++A  A E +  +DG  S+      +KR+L+ 
Sbjct: 15  MDKNSGS---NSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNRKRELSY 71

Query: 62  SSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSF 101
             + S N+ + R     + + +  PP +   S+   +SSF
Sbjct: 72  PKNESFNNQSRRSSSQKSKTFNKMPPQRGGGSSKLFSSSF 111


>gi|192807286 zinc finger and BTB domain containing 4 [Homo sapiens]
          Length = 1013

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 33/92 (35%), Positives = 44/92 (47%), Gaps = 14/92 (15%)

Query: 44  GNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCL 103
           G  +  P T+      +SSSSSSS+SS+      S+SSSSS PP  P  S+ P       
Sbjct: 72  GGAAPNPATTTAASSSSSSSSSSSSSSSSASS-SSSSSSSSPPPASPPASSPPRVLEL-P 129

Query: 104 GVSVAASSHVPIQKKLRFEDTLEFVGFDAKMA 135
           GV  AA           F D L F+ + A++A
Sbjct: 130 GVPAAA-----------FSDVLNFI-YSARLA 149


>gi|192807284 zinc finger and BTB domain containing 4 [Homo sapiens]
          Length = 1013

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 33/92 (35%), Positives = 44/92 (47%), Gaps = 14/92 (15%)

Query: 44  GNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCL 103
           G  +  P T+      +SSSSSSS+SS+      S+SSSSS PP  P  S+ P       
Sbjct: 72  GGAAPNPATTTAASSSSSSSSSSSSSSSSASS-SSSSSSSSPPPASPPASSPPRVLEL-P 129

Query: 104 GVSVAASSHVPIQKKLRFEDTLEFVGFDAKMA 135
           GV  AA           F D L F+ + A++A
Sbjct: 130 GVPAAA-----------FSDVLNFI-YSARLA 149


>gi|169166609 PREDICTED: similar to ribonucleic acid binding protein
           S1 isoform 6 [Homo sapiens]
          Length = 305

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 12/107 (11%)

Query: 3   SQSSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSS 62
           S SSGS       ++TS  G  +S   S+ +++    S+  G++ST+  +S+      SS
Sbjct: 67  SASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSA-SSRSGSSSTSRSSSS------SS 119

Query: 63  SSSSSNSSNEREDFDSTSSSSSTPPL-----QPRDSASPSTSSFCLG 104
           SS S + S  R D    S S S PP      + R S SP  +   +G
Sbjct: 120 SSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIG 166



 Score = 35.8 bits (81), Expect = 0.19
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 2/86 (2%)

Query: 8   SGDGNDDEATTSKDGGFSSPSP--SAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSS 65
           S D    + ++ KD G        SA++ +   RS +   +S+   TS      +SSSS+
Sbjct: 43  SKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSA 102

Query: 66  SSNSSNEREDFDSTSSSSSTPPLQPR 91
           SS S +      S+SSSSS  P   R
Sbjct: 103 SSRSGSSSTSRSSSSSSSSGSPSPSR 128



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 36/134 (26%), Positives = 50/134 (37%), Gaps = 30/134 (22%)

Query: 19  SKDGGFSSPSPSAAAAAQEV----RSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNERE 74
           +K     +PSP+      +     RS   G T  +      + K     S+SS SS+ R 
Sbjct: 18  NKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRS 77

Query: 75  DFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKM 134
              STSSS S+        +S S++S   G S  + S                       
Sbjct: 78  RSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRS----------------------- 114

Query: 135 AEESSSSSSSSSPT 148
              SSSSSSS SP+
Sbjct: 115 ---SSSSSSSGSPS 125



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 14/95 (14%)

Query: 10  DGNDDEATT-SKDGGF---SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSS 65
           D +D+++   SKD G    SS         ++ RSA+ G++ST           + SSS+
Sbjct: 33  DRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTR----------SRSSST 82

Query: 66  SSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSS 100
           SS+ S+      S SSSSS        S S S+SS
Sbjct: 83  SSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSS 117


>gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 737

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 41/177 (23%), Positives = 75/177 (42%), Gaps = 22/177 (12%)

Query: 27  PSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSS----- 81
           P P++   +  V S+T    +  PP S         +S+SS SS+      STSS     
Sbjct: 78  PPPASNEVSTSVLSST---ITPAPPMSVLSHHTLHITSNSSTSSSSTTSSTSTSSFITSS 134

Query: 82  -SSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSS 140
            ++ST       ++S +TS+     S++ +S   I   +    T             S++
Sbjct: 135 FTTSTSITSTSSTSSFTTSTATTSTSISITSTSSISSSITSTST-------------STT 181

Query: 141 SSSSSSPTAATSQQQQLKNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSAKKL 197
           S+SS+S T+  +      + S   S+ ++       + +ST+ +S + S   S +KL
Sbjct: 182 STSSNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTSTSTTSTSTTSTSTSATSSIRKL 238



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 35/157 (22%), Positives = 66/157 (42%), Gaps = 18/157 (11%)

Query: 44  GNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSSTPPLQPRD------SASPS 97
           G   T PP       + +S++    +SNE      +S+ +  PP+          +++ S
Sbjct: 56  GERDTAPPLMLPGPTIATSATRPPPASNEVSTSVLSSTITPAPPMSVLSHHTLHITSNSS 115

Query: 98  TSSFCLGVSVAASSHVPIQKKLRFEDTLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQL 157
           TSS     S + SS +          T  F    +     +SS+SS ++ TA TS    +
Sbjct: 116 TSSSSTTSSTSTSSFI----------TSSFT--TSTSITSTSSTSSFTTSTATTSTSISI 163

Query: 158 KNKSILISSVASVHHANGLAKSSTTVSSFANSKPGSA 194
            + S + SS+ S   +     S++T S+  ++   ++
Sbjct: 164 TSTSSISSSITSTSTSTTSTSSNSTTSTVTSTSTSTS 200



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 22/102 (21%), Positives = 48/102 (47%)

Query: 17  TTSKDGGFSSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDF 76
           +TS    F++ + + + +     +++  ++ T+  TS      NS++S+ +++S      
Sbjct: 143 STSSTSSFTTSTATTSTSISITSTSSISSSITSTSTSTTSTSSNSTTSTVTSTSTSTSTS 202

Query: 77  DSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKK 118
            STS+SS+        + S ST+S     + +     P QK+
Sbjct: 203 TSTSTSSTFTSTTSTSTTSTSTTSTSTSATSSIRKLTPHQKQ 244



 Score = 33.5 bits (75), Expect = 0.93
 Identities = 38/154 (24%), Positives = 67/154 (43%), Gaps = 27/154 (17%)

Query: 5   SSGSGDGNDDEATTSKDGGFSSPSPSAAAAAQEVRSATDGNTST-TPPTSAKKRKLNSSS 63
           +S S   +    +++    F + S + + +     S +   TST T  TS      +S S
Sbjct: 111 TSNSSTSSSSTTSSTSTSSFITSSFTTSTSITSTSSTSSFTTSTATTSTSISITSTSSIS 170

Query: 64  SSSSNSSNEREDFDSTSSSSSTPPLQPRDSASPSTSSFCLGVSVAASSHVPIQKKLRFED 123
           SS +++S       ST+S+SS        S S STS+     S + SS            
Sbjct: 171 SSITSTST------STTSTSSNSTTSTVTSTSTSTST---STSTSTSS------------ 209

Query: 124 TLEFVGFDAKMAEESSSSSSSSSPTAATSQQQQL 157
                 F +  +  ++S+S++S+ T+ATS  ++L
Sbjct: 210 -----TFTSTTSTSTTSTSTTSTSTSATSSIRKL 238



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 2/88 (2%)

Query: 25  SSPSPSAAAAAQEVRSATDGNTSTTPPTSAKKRKLNSSSSSSSNSSNEREDFDSTSSSSS 84
           +S S ++ ++     + T  +TST+  TS       +S++S+S +S       STS++SS
Sbjct: 176 TSTSTTSTSSNSTTSTVTSTSTSTSTSTSTSTSSTFTSTTSTSTTSTSTTS-TSTSATSS 234

Query: 85  TPPLQP-RDSASPSTSSFCLGVSVAASS 111
              L P +       S+F  G+S+  S+
Sbjct: 235 IRKLTPHQKQCGALASAFLFGLSLLVST 262


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,007,710
Number of Sequences: 37866
Number of extensions: 1339005
Number of successful extensions: 14169
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 346
Number of HSP's that attempted gapping in prelim test: 9632
Number of HSP's gapped (non-prelim): 2882
length of query: 913
length of database: 18,247,518
effective HSP length: 111
effective length of query: 802
effective length of database: 14,044,392
effective search space: 11263602384
effective search space used: 11263602384
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press