Guide to the Human Genome
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Search of human proteins with 120953291

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|120953291 folliculin interacting protein 1 isoform 1 [Homo
sapiens]
         (1166 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|120953291 folliculin interacting protein 1 isoform 1 [Homo sa...  2352   0.0  
gi|120953264 folliculin interacting protein 1 isoform 2 [Homo sa...  2282   0.0  
gi|154689769 folliculin interacting protein 2 [Homo sapiens]          670   0.0  
gi|209969819 hypothetical protein LOC253143 [Homo sapiens]             37   0.084
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]             36   0.24 
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]                         36   0.24 
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]                         36   0.24 
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]                         36   0.24 
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]                         36   0.24 
gi|13491168 pumilio homolog 2 [Homo sapiens]                           35   0.42 
gi|134152667 ICBP90 binding protein 1 [Homo sapiens]                   34   0.71 
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]          33   1.6  
gi|16445033 ACRC protein [Homo sapiens]                                33   1.6  
gi|38569484 kinesin family member 21A [Homo sapiens]                   33   2.1  
gi|150170670 piccolo isoform 2 [Homo sapiens]                          33   2.1  
gi|150378539 piccolo isoform 1 [Homo sapiens]                          33   2.1  
gi|31742492 Nedd4 binding protein 2 [Homo sapiens]                     33   2.1  
gi|88759339 aster-associated protein [Homo sapiens]                    33   2.1  
gi|38788333 remodeling and spacing factor 1 [Homo sapiens]             32   2.7  
gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]         32   4.6  
gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]         32   4.6  
gi|154426278 hypothetical protein LOC90523 [Homo sapiens]              32   4.6  
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    31   6.0  
gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13...    31   6.0  
gi|189083849 delta-aminolevulinic acid dehydratase [Homo sapiens]      31   6.0  
gi|208431829 eukaryotic translation initiation factor 2-alpha ki...    31   7.9  
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni...    31   7.9  
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit...    31   7.9  
gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens]    31   7.9  
gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens]    31   7.9  

>gi|120953291 folliculin interacting protein 1 isoform 1 [Homo
            sapiens]
          Length = 1166

 Score = 2352 bits (6095), Expect = 0.0
 Identities = 1166/1166 (100%), Positives = 1166/1166 (100%)

Query: 1    MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRLIVYQDCERRGRNVLFD 60
            MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRLIVYQDCERRGRNVLFD
Sbjct: 1    MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRLIVYQDCERRGRNVLFD 60

Query: 61   SSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSDIKDQCLKYQGS 120
            SSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSDIKDQCLKYQGS
Sbjct: 61   SSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSDIKDQCLKYQGS 120

Query: 121  RCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQD 180
            RCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQD
Sbjct: 121  RCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQD 180

Query: 181  SLEFINQDNNTLKADNNTVINGLLGNIGLSQFCSPRRAFSEQGPLRLIRSASFFAVHSNP 240
            SLEFINQDNNTLKADNNTVINGLLGNIGLSQFCSPRRAFSEQGPLRLIRSASFFAVHSNP
Sbjct: 181  SLEFINQDNNTLKADNNTVINGLLGNIGLSQFCSPRRAFSEQGPLRLIRSASFFAVHSNP 240

Query: 241  MDMPGRELNEDRDSGIARSASLSSLLITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENG 300
            MDMPGRELNEDRDSGIARSASLSSLLITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENG
Sbjct: 241  MDMPGRELNEDRDSGIARSASLSSLLITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENG 300

Query: 301  VFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFE 360
            VFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFE
Sbjct: 301  VFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFE 360

Query: 361  SHMNKLKSAIEQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTMPRIGEPVWLT 420
            SHMNKLKSAIEQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTMPRIGEPVWLT
Sbjct: 361  SHMNKLKSAIEQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTMPRIGEPVWLT 420

Query: 421  MMSGTPEKNHLCYRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKI 480
            MMSGTPEKNHLCYRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKI
Sbjct: 421  MMSGTPEKNHLCYRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKI 480

Query: 481  FLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLLYFLT 540
            FLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLLYFLT
Sbjct: 481  FLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLLYFLT 540

Query: 541  YFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKES 600
            YFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKES
Sbjct: 541  YFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKES 600

Query: 601  EEIRTPNCNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENA 660
            EEIRTPNCNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENA
Sbjct: 601  EEIRTPNCNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENA 660

Query: 661  VDVKQYRDKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHTGK 720
            VDVKQYRDKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHTGK
Sbjct: 661  VDVKQYRDKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHTGK 720

Query: 721  AMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHH 780
            AMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHH
Sbjct: 721  AMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHH 780

Query: 781  TKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFN 840
            TKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFN
Sbjct: 781  TKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFN 840

Query: 841  DDSIETRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTCF 900
            DDSIETRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTCF
Sbjct: 841  DDSIETRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTCF 900

Query: 901  PQQDQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVS 960
            PQQDQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVS
Sbjct: 901  PQQDQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVS 960

Query: 961  SYYGGEQEDWAEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSD 1020
            SYYGGEQEDWAEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSD
Sbjct: 961  SYYGGEQEDWAEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSD 1020

Query: 1021 ERFRQCLMSDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVS 1080
            ERFRQCLMSDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVS
Sbjct: 1021 ERFRQCLMSDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVS 1080

Query: 1081 SLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVL 1140
            SLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVL
Sbjct: 1081 SLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVL 1140

Query: 1141 GIESSDLPLLAAVASTHSPYVAQILL 1166
            GIESSDLPLLAAVASTHSPYVAQILL
Sbjct: 1141 GIESSDLPLLAAVASTHSPYVAQILL 1166


>gi|120953264 folliculin interacting protein 1 isoform 2 [Homo
            sapiens]
          Length = 1138

 Score = 2282 bits (5914), Expect = 0.0
 Identities = 1138/1166 (97%), Positives = 1138/1166 (97%), Gaps = 28/1166 (2%)

Query: 1    MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRLIVYQDCERRGRNVLFD 60
            MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRLIVYQDCERRGRNVLFD
Sbjct: 1    MAPTLFQKLFSKRTGLGAPGRDARDPDCGFSWPLPEFDPSQIRLIVYQDCERRGRNVLFD 60

Query: 61   SSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSDIKDQCLKYQGS 120
            SSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSDIKDQCLKYQGS
Sbjct: 61   SSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSDIKDQCLKYQGS 120

Query: 121  RCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQD 180
            RCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQD
Sbjct: 121  RCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSSICGSLNTLQD 180

Query: 181  SLEFINQDNNTLKADNNTVINGLLGNIGLSQFCSPRRAFSEQGPLRLIRSASFFAVHSNP 240
            SLEFINQDNNTLKADNNTVINGLLGNI                            VHSNP
Sbjct: 181  SLEFINQDNNTLKADNNTVINGLLGNI----------------------------VHSNP 212

Query: 241  MDMPGRELNEDRDSGIARSASLSSLLITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENG 300
            MDMPGRELNEDRDSGIARSASLSSLLITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENG
Sbjct: 213  MDMPGRELNEDRDSGIARSASLSSLLITPFPSPNSSLTRSCASSYQRRWRRSQTTSLENG 272

Query: 301  VFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFE 360
            VFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFE
Sbjct: 273  VFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNEFFFSHFPLFE 332

Query: 361  SHMNKLKSAIEQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTMPRIGEPVWLT 420
            SHMNKLKSAIEQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTMPRIGEPVWLT
Sbjct: 333  SHMNKLKSAIEQAMKMSRRSADASQRSLAYNRIVDALNEFRTTICNLYTMPRIGEPVWLT 392

Query: 421  MMSGTPEKNHLCYRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKI 480
            MMSGTPEKNHLCYRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKI
Sbjct: 393  MMSGTPEKNHLCYRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPTVMPNGQPPIKI 452

Query: 481  FLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLLYFLT 540
            FLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLLYFLT
Sbjct: 453  FLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLLYFLT 512

Query: 541  YFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKES 600
            YFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKES
Sbjct: 513  YFIRCSELQETHLLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKES 572

Query: 601  EEIRTPNCNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENA 660
            EEIRTPNCNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENA
Sbjct: 573  EEIRTPNCNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENA 632

Query: 661  VDVKQYRDKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHTGK 720
            VDVKQYRDKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHTGK
Sbjct: 633  VDVKQYRDKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHTGK 692

Query: 721  AMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHH 780
            AMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHH
Sbjct: 693  AMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHH 752

Query: 781  TKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFN 840
            TKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFN
Sbjct: 753  TKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFN 812

Query: 841  DDSIETRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTCF 900
            DDSIETRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTCF
Sbjct: 813  DDSIETRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTCF 872

Query: 901  PQQDQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVS 960
            PQQDQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVS
Sbjct: 873  PQQDQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVS 932

Query: 961  SYYGGEQEDWAEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSD 1020
            SYYGGEQEDWAEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSD
Sbjct: 933  SYYGGEQEDWAEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSD 992

Query: 1021 ERFRQCLMSDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVS 1080
            ERFRQCLMSDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVS
Sbjct: 993  ERFRQCLMSDLSHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVS 1052

Query: 1081 SLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVL 1140
            SLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVL
Sbjct: 1053 SLVSNLLHSTLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVL 1112

Query: 1141 GIESSDLPLLAAVASTHSPYVAQILL 1166
            GIESSDLPLLAAVASTHSPYVAQILL
Sbjct: 1113 GIESSDLPLLAAVASTHSPYVAQILL 1138


>gi|154689769 folliculin interacting protein 2 [Homo sapiens]
          Length = 1114

 Score =  670 bits (1729), Expect = 0.0
 Identities = 404/789 (51%), Positives = 503/789 (63%), Gaps = 60/789 (7%)

Query: 1   MAPTLFQKLFSKRTGLG---APGRDARDPDCG--FSWPLPEFDPSQIRLIVYQDCERRGR 55
           MAPTL QKLF+KR   G   A     R P  G  FSW   EFD ++IRLIVYQDC+RRGR
Sbjct: 1   MAPTLLQKLFNKRGSSGSSAAASAQGRAPKEGPAFSWSCSEFDLNEIRLIVYQDCDRRGR 60

Query: 56  NVLFDSSVKRRNEDISVSKLCSDAQVKVFGKCCQLKPGGDSSSSLDSSVTSSSD-----I 110
            VLFDS   ++ E+++  K   D  +K+  KCCQ      SSSS   S  SSS       
Sbjct: 61  QVLFDSKAVQKIEEVTAQKT-EDVPIKISAKCCQGSSSVSSSSSSSISSHSSSGGSSHHA 119

Query: 111 KDQCLKYQGSRCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLSKVFTARTGSS 170
           K+Q  KYQ +R +SD NMLGEMMFGSVAMSYKGSTLKIH IRSPPQLM+SKVF+AR GS 
Sbjct: 120 KEQLPKYQYTRPASDVNMLGEMMFGSVAMSYKGSTLKIHYIRSPPQLMISKVFSARMGS- 178

Query: 171 ICGSLNTLQDSLEFINQDNNTLKADNNTVINGLLGNIGLSQFCSPRRAFSEQGPLRLIRS 230
            CGS N LQDS E+INQD N  K + N                        Q  L   R+
Sbjct: 179 FCGSTNNLQDSFEYINQDPNLGKLNTN------------------------QNSLGPCRT 214

Query: 231 ASFFAVHSNPMDMPGRELNEDRDSGIARSASLSSLLITPFPSPNSSLTRSCASSYQRRWR 290
            S  A HS P+DMP R  NEDRDSGIARSASLSSLLITPFPSP+SS + S  SSYQRRW 
Sbjct: 215 GSNLA-HSTPVDMPSRGQNEDRDSGIARSASLSSLLITPFPSPSSSTSSS--SSYQRRWL 271

Query: 291 RSQTTSLENGVFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGVIFSLSKDEDENNKFNE 350
           RSQTTSLENG+ PR S +E+F+L++E+C  NP +VR+KKIAI +IFSL + E+    F +
Sbjct: 272 RSQTTSLENGIIPRRSTDETFSLAEETCSSNPAMVRRKKIAISIIFSLCEKEEAQRNFQD 331

Query: 351 FFFSHFPLFESHMNKLKSAIEQAMKMSRRSADASQRSLAY-NRIVDALNEFRTTICNLYT 409
           FFFSHFPLFESHMN+LKSAIE+AM   R+ A++S R   Y +R+++AL EFR TI NLY+
Sbjct: 332 FFFSHFPLFESHMNRLKSAIEKAMISCRKIAESSLRVQFYVSRLMEALGEFRGTIWNLYS 391

Query: 410 MPRIGEPVWLTMMSGTPEKNHLCYRFMKEFTFLMENASKNQFLPALITAVLTNHLAWVPT 469
           +PRI EPVWLTMMSGT EKN LC RF+KEFT L+E  +KNQF  AL+TAVLT HLAWVPT
Sbjct: 392 VPRIAEPVWLTMMSGTLEKNQLCQRFLKEFTLLIEQINKNQFFAALLTAVLTYHLAWVPT 451

Query: 470 VMPNGQPPIKIFLEKHSSQSVDMLAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQ 529
           VMP   PPIK F EK +SQSV+MLAKTHPYNPLWAQLGDLYGAIGSPVRL RTVVVGK++
Sbjct: 452 VMPVDHPPIKAFSEKRTSQSVNMLAKTHPYNPLWAQLGDLYGAIGSPVRLTRTVVVGKQK 511

Query: 530 DMVQRLLYFLTYFIRCSELQETHLLENGE--DEAIVMPGTVITTTLEKGEIEESEYVLVT 587
           D+VQR+LY LTYF+RCSELQE  L  +G   +   V+ G+ I T LEKGE+EESEYV++T
Sbjct: 512 DLVQRILYVLTYFLRCSELQENQLTWSGNHGEGDQVLNGSKIITALEKGEVEESEYVVIT 571

Query: 588 MHRNKSSLLFKESEEIRTPNCNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGISDEC 647
           + RN+ +L+            N      P   +  ++     + D + + +   G S+ C
Sbjct: 572 V-RNEPALVPPILPPTAAERHNPWPTGFPECPEGTDSRDLGLKPDKEANRRPEQG-SEAC 629

Query: 648 QMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQ 707
                    + +      ++ +   C D K +     GS  +  C +  +G++  ++   
Sbjct: 630 SAGCLGPASDAS------WKPQNAFCGDEKNKEAPQDGSSRLPSCEVLGAGMKMDQQA-- 681

Query: 708 SEKLLDSDSHTGKAMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTEL 767
             +LL  +  T    RS    V    PD+ +    S E    KVTF IG   SP+SD E 
Sbjct: 682 VCELLKVEMPTRLPDRS----VAWPCPDRHLREKPSLE----KVTFQIGSFASPESDFES 733

Query: 768 RSQAVVDQI 776
           R + + +++
Sbjct: 734 RMKKMEERV 742



 Score =  313 bits (801), Expect = 8e-85
 Identities = 167/255 (65%), Positives = 196/255 (76%), Gaps = 11/255 (4%)

Query: 913  VPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVSSYYGGEQEDWAE 972
            +P GD    +KK    TE DIPRNESSDSALGDS+ E     M   +   +GG++   + 
Sbjct: 870  IPCGD---DNKKANFRTEGDIPRNESSDSALGDSDDEACASAM---LDLGHGGDRTGGSL 923

Query: 973  EDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSDERFRQCLMSDLS 1032
            E E+P P S+ I       N+ NFGRSLL GYC +Y+PD VL G GSDE+ +QCL++DL 
Sbjct: 924  EVELPLPRSQSISTQ----NVRNFGRSLLAGYCPTYMPDLVLHGTGSDEKLKQCLVADLV 979

Query: 1033 HAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDN-KLGKEVLVSSLVSNLLHSTL 1091
            H V HPVLDEPIAEAVCIIAD DKW+VQVA+SQR+VTDN KLG++VLVSS VS+LL S L
Sbjct: 980  HTVHHPVLDEPIAEAVCIIADTDKWSVQVATSQRKVTDNMKLGQDVLVSSQVSSLLQSIL 1039

Query: 1092 QLYKHNLSPNFCVMHLEDRLQELYFKSKMLSEYLRGQMRVHVKELGVVLGIESSDLPLLA 1151
            QLYK +L  +FC+MHLEDRLQE+Y KSKMLSEYLRG  RVHVKELGVVLGIES+DLPLL 
Sbjct: 1040 QLYKLHLPADFCIMHLEDRLQEMYLKSKMLSEYLRGHTRVHVKELGVVLGIESNDLPLLT 1099

Query: 1152 AVASTHSPYVAQILL 1166
            A+ASTHSPYVAQILL
Sbjct: 1100 AIASTHSPYVAQILL 1114


>gi|209969819 hypothetical protein LOC253143 [Homo sapiens]
          Length = 2151

 Score = 37.4 bits (85), Expect = 0.084
 Identities = 93/461 (20%), Positives = 167/461 (36%), Gaps = 102/461 (22%)

Query: 515  SPVRLARTVVVGKRQDMVQRLLYFLTYFIRCSELQETHLLEN--GEDEAIVMPGTVITTT 572
            S ++L+   + GK QD V +   F  Y I    +QE +   N  G ++ +    TV+ ++
Sbjct: 894  SSIKLSEEGLEGKEQD-VSKETVFCKYNISDHAIQELNQTVNIPGPEKVLDQSPTVMFSS 952

Query: 573  LEKGEIEESEYVLVTMHRNKSSLLFKESEEIRTPNCNCKYCSHPLLGQNV-ENISQQERE 631
             +  +  E      T+ +    +L  +S + R   C  +       GQ+  E +S  +RE
Sbjct: 953  FKNVKSVE------TLDQKADEVLDCQSNQNRPDECKSE-------GQSAKEMLSSDQRE 999

Query: 632  -------DIQNSSKELL-----------GISDECQM----ISPSDCQE--ENAVDVKQYR 667
                   ++ ++ K+LL           G   +C +    +  S C E  E  VD+  Y 
Sbjct: 1000 TVTEPHGEVNHNQKDLLVSSGSNNSLPCGSPKKCNLKGAFVKMSGCDESTEGMVDIV-YT 1058

Query: 668  DKLRTCFDAKLETVVCTGSVPVDKCALSESGLESTEETWQ--SEKLLDSDSHTGKAMRST 725
            D    C +   E V+   +  +  C   +  L   E++    S + LD+ +HTG   + +
Sbjct: 1059 D----CSNKLAEGVLDVKASNLLDCGARQEKLAFQEDSRSTLSRRELDA-AHTGTTGQDS 1113

Query: 726  GMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQITRHHTKPLK 785
               V        +    SCE    +          PDS      ++V D       +P K
Sbjct: 1114 DFPVTAASTVDFLKIKKSCEENVCRSLKDCEMEKCPDSCAH-EMESVADH------EPNK 1166

Query: 786  EERGAIDQHQETKQTTKDQSGES--DTQNMVSEEPCEL-------PCWNHSDPESMSLFD 836
               G ++         +   G S  +TQ M      E          +  S  ESMS  D
Sbjct: 1167 RILGRVNLSLNDSHYGQQDKGTSLRETQEMTEGSRLEPNSEFGKESTFGISSKESMSCHD 1226

Query: 837  EYFNDDSIETRTIDDVPFKTSTDSKD-----------HCCMLEFSKILCTK--------- 876
            E     S+  R++  +    S ++ +           + C  +  ++LC           
Sbjct: 1227 E----SSVSLRSLKSIEIMPSQENSETNVNSEETDLKNLCKPKDGEMLCENVKDCTVLPE 1282

Query: 877  ----------NNKQNNEFCKCIETVPQDSCKTCFPQQDQRD 907
                      N+   +  C C+E   +++CK C P ++  D
Sbjct: 1283 MKEIVSRDWSNSSDRDSVCTCVE---KNACKACHPHENSSD 1320


>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
          Length = 2440

 Score = 35.8 bits (81), Expect = 0.24
 Identities = 48/236 (20%), Positives = 85/236 (36%), Gaps = 22/236 (9%)

Query: 585 LVTMHRNKSSLLFKESEEIRTPNCNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGIS 644
           L+  H+ K+S   +E  ++      C+  +          +S QE EDI+ S++E     
Sbjct: 678 LLQQHKQKTSRKPREERDVS----QCESVA--------STVSAQEDEDIEASNEEENPED 725

Query: 645 DECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVCTG---SVPVDKCALSESGLES 701
            E + + PS+   ENA         +    +   ET   T    +VP  K A  ES    
Sbjct: 726 SEVEAVKPSEDSPENATSRGNTEPAVE--LEPTTETAPSTSPSLAVPSTKPAEDESVETQ 783

Query: 702 TEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSP 761
             ++  +E     D    +     G V +  P  K           +   + + GD+ + 
Sbjct: 784 VNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPENHASKVEGDN-TK 842

Query: 762 DSDTELRSQAV----VDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGESDTQNM 813
           + D +  S+ V     D +        + E  + +    T    +D  GE + Q M
Sbjct: 843 ERDLDRASEKVEPRDEDLVVAQQINAQRPEPQSDNDSSATCSADEDVDGEPERQRM 898


>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
          Length = 1881

 Score = 35.8 bits (81), Expect = 0.24
 Identities = 26/93 (27%), Positives = 48/93 (51%), Gaps = 3/93 (3%)

Query: 625 ISQQEREDIQNSSKELLGIS-DECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVC 683
           +S + R     +  E+L +S DE + +     +  ++ DV + ++ L   F  KL+ VV 
Sbjct: 798 VSDKHRMSFPETVDEILDVSEDEGEELISFKAERRDSRDVDEEKELLD--FVPKLDQVVE 855

Query: 684 TGSVPVDKCALSESGLESTEETWQSEKLLDSDS 716
           + ++P   CA+ E+ +  +EE  Q+ K  D DS
Sbjct: 856 SPAIPRIPCAMPETVVIRSEEQEQASKEYDEDS 888


>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
          Length = 1880

 Score = 35.8 bits (81), Expect = 0.24
 Identities = 26/93 (27%), Positives = 48/93 (51%), Gaps = 3/93 (3%)

Query: 625 ISQQEREDIQNSSKELLGIS-DECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVC 683
           +S + R     +  E+L +S DE + +     +  ++ DV + ++ L   F  KL+ VV 
Sbjct: 798 VSDKHRMSFPETVDEILDVSEDEGEELISFKAERRDSRDVDEEKELLD--FVPKLDQVVE 855

Query: 684 TGSVPVDKCALSESGLESTEETWQSEKLLDSDS 716
           + ++P   CA+ E+ +  +EE  Q+ K  D DS
Sbjct: 856 SPAIPRIPCAMPETVVIRSEEQEQASKEYDEDS 888


>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
          Length = 1719

 Score = 35.8 bits (81), Expect = 0.24
 Identities = 26/93 (27%), Positives = 48/93 (51%), Gaps = 3/93 (3%)

Query: 625 ISQQEREDIQNSSKELLGIS-DECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVC 683
           +S + R     +  E+L +S DE + +     +  ++ DV + ++ L   F  KL+ VV 
Sbjct: 798 VSDKHRMSFPETVDEILDVSEDEGEELISFKAERRDSRDVDEEKELLD--FVPKLDQVVE 855

Query: 684 TGSVPVDKCALSESGLESTEETWQSEKLLDSDS 716
           + ++P   CA+ E+ +  +EE  Q+ K  D DS
Sbjct: 856 SPAIPRIPCAMPETVVIRSEEQEQASKEYDEDS 888


>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
          Length = 1856

 Score = 35.8 bits (81), Expect = 0.24
 Identities = 26/93 (27%), Positives = 48/93 (51%), Gaps = 3/93 (3%)

Query: 625 ISQQEREDIQNSSKELLGIS-DECQMISPSDCQEENAVDVKQYRDKLRTCFDAKLETVVC 683
           +S + R     +  E+L +S DE + +     +  ++ DV + ++ L   F  KL+ VV 
Sbjct: 798 VSDKHRMSFPETVDEILDVSEDEGEELISFKAERRDSRDVDEEKELLD--FVPKLDQVVE 855

Query: 684 TGSVPVDKCALSESGLESTEETWQSEKLLDSDS 716
           + ++P   CA+ E+ +  +EE  Q+ K  D DS
Sbjct: 856 SPAIPRIPCAMPETVVIRSEEQEQASKEYDEDS 888


>gi|13491168 pumilio homolog 2 [Homo sapiens]
          Length = 1064

 Score = 35.0 bits (79), Expect = 0.42
 Identities = 35/126 (27%), Positives = 57/126 (45%), Gaps = 13/126 (10%)

Query: 692 CALSESGLESTEETWQSEKLLDSDSHTGKAMR-STGMVVEKKPPDKIVPAS--FSCEAAQ 748
           C + +  LES     QSE + + D H  K ++   G  V +K  + + P S  F  +A +
Sbjct: 813 CRVIQKALESISSDQQSEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFK 872

Query: 749 TKVTFLIGDSMSPDSDTELRSQAVVDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGES 808
            +V  L   S  P     +  Q +++  T   T P+ EE      HQ T+Q  +DQ G  
Sbjct: 873 GQVFVL---STHPYGCRVI--QRILEHCTAEQTLPILEE-----LHQHTEQLVQDQYGNY 922

Query: 809 DTQNMV 814
             Q+++
Sbjct: 923 VIQHVL 928


>gi|134152667 ICBP90 binding protein 1 [Homo sapiens]
          Length = 1440

 Score = 34.3 bits (77), Expect = 0.71
 Identities = 28/126 (22%), Positives = 54/126 (42%), Gaps = 10/126 (7%)

Query: 699 LESTEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIV-------PASFSCEAAQTKV 751
           L+   +  Q +   D++S TG  +++    +    P   V       P +   ++A +  
Sbjct: 841 LKEVLQRLQEQLTKDTESMTGSPLQNQTACIGVLFPSAEVALLMHPAPGAVDADSAGSDS 900

Query: 752 TFLIGDSMSPDSDTELRSQAVVDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGESDTQ 811
           T L+   +SP  D EL+S A  DQ      K L+E   +  ++Q+  Q     +GE    
Sbjct: 901 TSLVDSELSPSEDRELKSDASSDQGPASPEKVLEE---SSIENQDVSQERPHSNGELQDS 957

Query: 812 NMVSEE 817
             ++++
Sbjct: 958 GPLAQQ 963


>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
          Length = 2964

 Score = 33.1 bits (74), Expect = 1.6
 Identities = 37/155 (23%), Positives = 67/155 (43%), Gaps = 15/155 (9%)

Query: 690  DKCALSESGLESTEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIVPASFSCEAAQT 749
            DK   ++  L+   +  +++KL    + TG           +K P + V +  + +AAQ 
Sbjct: 1814 DKILATKKNLDHVNKILKAKKL-QRQARTGNNFVKRRPGRPRKCPLQAVVSMQAFQAAQF 1872

Query: 750  KVTFLIGDS------MSPDSDTELRSQAVVDQITRH--HTKPLKEERGAIDQHQETKQTT 801
                L  D       +SPD+ T++  +AVV  +  +  H K LK +   +++    KQ  
Sbjct: 1873 VNPELNRDEEGAALHLSPDTVTDV-IEAVVQSVNLNPEHKKGLKRKGWLLEEQTRKKQKP 1931

Query: 802  KDQSGESDTQNMVSEEPCELPCWNH-----SDPES 831
              +  E +     +E P E+P  +      S+PES
Sbjct: 1932 LPEEEEQENNKSFNEAPVEIPSPSETPAKPSEPES 1966


>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 33.1 bits (74), Expect = 1.6
 Identities = 59/263 (22%), Positives = 98/263 (37%), Gaps = 16/263 (6%)

Query: 792  DQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFNDDSIETRTIDD 851
            D + +  +   D S +S+  +  S++  E P  N  D E+    D+  +D  +     DD
Sbjct: 140  DDNSDDSEAPDDNSDDSEAPDDNSDDS-EAPDDNSDDSEAP---DDNSDDSDVPDDNSDD 195

Query: 852  VPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIET-VPQDSCKTCFPQQDQRDTLS 910
                 S DS D     + S +   K++  +       ++ VP DS        D  D   
Sbjct: 196  SSDDNSDDSSDDNS--DDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSE 253

Query: 911  ILVPHGDK-----ESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTR--QVSSYY 963
                  D      +SSD   A     D   +E+SD +  DSE+ D   D +      S  
Sbjct: 254  APDDSSDDSEAPDDSSDDSEAPDDSSD--DSEASDDSSDDSEASDDSSDDSEAPDDKSDD 311

Query: 964  GGEQEDWAEEDEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSDERF 1023
                ED +++ ++P   S  +EV     ++ N G+              V Q   SD+  
Sbjct: 312  SDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAG 371

Query: 1024 RQCLMSDLSHAVQHPVLDEPIAE 1046
             Q L  +LS     P  +  ++E
Sbjct: 372  EQDLGENLSKPPSDPEANPEVSE 394


>gi|38569484 kinesin family member 21A [Homo sapiens]
          Length = 1661

 Score = 32.7 bits (73), Expect = 2.1
 Identities = 31/163 (19%), Positives = 67/163 (41%), Gaps = 8/163 (4%)

Query: 918  KESSDKKIAVGTE--WDIPRNESSDSALGDSESEDTGHDMTRQVSSYYGGEQEDWAEEDE 975
            KE   KK   G E   D  + +  +  + + E+ +   + +++VS +   E+E+  EED+
Sbjct: 551  KEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDD 610

Query: 976  IPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSDERFRQCLMSDLSH-- 1033
            I   G    E  +     AN+   L    C   +   ++  + + ++  Q L        
Sbjct: 611  ID-GGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKL 669

Query: 1034 -AVQHPVLDEPIA--EAVCIIADMDKWTVQVASSQRRVTDNKL 1073
              +QH + D  +   + +  +  ++ ++ + A   R   + KL
Sbjct: 670  MMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKL 712


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 32.7 bits (73), Expect = 2.1
 Identities = 87/439 (19%), Positives = 165/439 (37%), Gaps = 96/439 (21%)

Query: 617  LLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENAVDVKQYRDKLRTCFDA 676
            L+ +  + +  +  + I    KE L +     M++    QEE+ ++    +DK  +    
Sbjct: 1156 LVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE----KDKA-SALQE 1210

Query: 677  KLETVVCTGSVPVDKCALSESG---LESTEETWQSEKLLDS------DSHTGKAMRSTGM 727
            K         +P ++   SE     LE  + T + +KLL        +      ++S   
Sbjct: 1211 KKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQ 1270

Query: 728  VVEKKPPDKIVPASFS-CEAAQTKVTFL-IGDSMSPDSDTELRSQAVVDQITRHHTKPLK 785
            + E+K   ++ P +    +  QTK+  L  G   S   + +  ++ + +Q       P  
Sbjct: 1271 IAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ-------PQP 1323

Query: 786  EERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFNDDSIE 845
                  DQ +  K+ T+ +  +SDT +  S++P          P+ +S  D  ++ D I 
Sbjct: 1324 PCTAKPDQVEPGKEKTEKEDDKSDTSS--SQQP--------KSPQGLS--DTGYSSDGIS 1371

Query: 846  TRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETV-------------- 891
            + ++ ++P    TD KD    L+        +    ++  K   TV              
Sbjct: 1372 S-SLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADE 1430

Query: 892  ---------------PQDSCKTCFPQQDQRDTLSILVPHGD-KESSDKK---IAVGTEWD 932
                           P+D  KT    Q   +TL I +   + KES +++       ++ D
Sbjct: 1431 KSEKKTQPHEVSPEQPKDQEKT----QSLSETLEITISEEEIKESQEERKDTFKKDSQQD 1486

Query: 933  IP-----------------RNESSDSALGDSESEDTGHDMTRQVSSYYGGEQEDWAEED- 974
            IP                 R E  DS    SESE++     ++ +S      +++ +ED 
Sbjct: 1487 IPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDS 1546

Query: 975  -----EIPFPGSKLIEVSA 988
                 E  F   ++IE+SA
Sbjct: 1547 QGSGEEEDFIRKQIIEMSA 1565


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 32.7 bits (73), Expect = 2.1
 Identities = 87/439 (19%), Positives = 165/439 (37%), Gaps = 96/439 (21%)

Query: 617  LLGQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENAVDVKQYRDKLRTCFDA 676
            L+ +  + +  +  + I    KE L +     M++    QEE+ ++    +DK  +    
Sbjct: 1156 LVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE----KDKA-SALQE 1210

Query: 677  KLETVVCTGSVPVDKCALSESG---LESTEETWQSEKLLDS------DSHTGKAMRSTGM 727
            K         +P ++   SE     LE  + T + +KLL        +      ++S   
Sbjct: 1211 KKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQ 1270

Query: 728  VVEKKPPDKIVPASFS-CEAAQTKVTFL-IGDSMSPDSDTELRSQAVVDQITRHHTKPLK 785
            + E+K   ++ P +    +  QTK+  L  G   S   + +  ++ + +Q       P  
Sbjct: 1271 IAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ-------PQP 1323

Query: 786  EERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFNDDSIE 845
                  DQ +  K+ T+ +  +SDT +  S++P          P+ +S  D  ++ D I 
Sbjct: 1324 PCTAKPDQVEPGKEKTEKEDDKSDTSS--SQQP--------KSPQGLS--DTGYSSDGIS 1371

Query: 846  TRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETV-------------- 891
            + ++ ++P    TD KD    L+        +    ++  K   TV              
Sbjct: 1372 S-SLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADE 1430

Query: 892  ---------------PQDSCKTCFPQQDQRDTLSILVPHGD-KESSDKK---IAVGTEWD 932
                           P+D  KT    Q   +TL I +   + KES +++       ++ D
Sbjct: 1431 KSEKKTQPHEVSPEQPKDQEKT----QSLSETLEITISEEEIKESQEERKDTFKKDSQQD 1486

Query: 933  IP-----------------RNESSDSALGDSESEDTGHDMTRQVSSYYGGEQEDWAEED- 974
            IP                 R E  DS    SESE++     ++ +S      +++ +ED 
Sbjct: 1487 IPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDS 1546

Query: 975  -----EIPFPGSKLIEVSA 988
                 E  F   ++IE+SA
Sbjct: 1547 QGSGEEEDFIRKQIIEMSA 1565


>gi|31742492 Nedd4 binding protein 2 [Homo sapiens]
          Length = 1770

 Score = 32.7 bits (73), Expect = 2.1
 Identities = 71/388 (18%), Positives = 137/388 (35%), Gaps = 37/388 (9%)

Query: 493 LAKTHPYNPLWAQLGDLYGAIGSPVRLARTVVVGKRQDMVQRLLYFLTYFIRCSELQETH 552
           L++ H Y  L+ +    +     P  LAR  + G  ++ + R+L     F+    +  + 
Sbjct: 529 LSQKHKYKVLFREPDTWWKF--KPKELARRNIHGVSKEKITRMLEHYQRFVSVPIIMSSS 586

Query: 553 LLENGEDEAIVMPGTVITTTLEKGEIEESEYVLVTMHRNKSSLLFKESEEIRTPNCNCKY 612
           + E  E   +        +T  +    + E ++     N  SL  K  E   T   N   
Sbjct: 587 VPEKIERIELCAYSCEDRSTSPR----DDEDIISEKEENILSLSLKHLEF--TEEKNLDV 640

Query: 613 CSHPLLGQNVENISQQE----REDIQNSSKEL----------LGISDECQMISPSDCQEE 658
               +L +NV  +S  +    R++I + +  +          +  SD    +  +D  E 
Sbjct: 641 TKETMLPENVAYLSNADLNKRRKEISDMNPSIQSALILETPHMYFSDSESKLQATDKSEN 700

Query: 659 NAVDVKQYRDKLRTCFDAKLETV---VCTGSVPVDKCALSESGLESTEETWQSEKLLDSD 715
             +++   +   +T  D+ +E V    C      + C L+ SG    E++   E + +  
Sbjct: 701 EQIEMVAVKGYSKTDTDSSMERVSPSTCCSENNQEDCDLANSGPLQNEKSSPGEIVEERA 760

Query: 716 SHTGKAMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMSPDSDTELRSQAVVDQ 775
           + T KA    G    K   +K      S       V   IG     +  TE  S    D+
Sbjct: 761 TVTKKAF---GKQKSKSTLEKFPRHELSNFVGDWPVDKTIGQRTKRNRKTEKTSSVQSDK 817

Query: 776 ITRHHTKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLF 835
              +          +++     ++ +  +S E   ++          C + S+P +   +
Sbjct: 818 KYNYPQSHKLVNSVSVNTDCVQQRGSPHESVEDGRKSQ---------CDDASEPLNSYKY 868

Query: 836 DEYFNDDSIETRTIDDVPFKTSTDSKDH 863
           D Y N D      + D P   S   ++H
Sbjct: 869 DAYKNIDKNSFNIMGDWPSSDSLAQREH 896


>gi|88759339 aster-associated protein [Homo sapiens]
          Length = 647

 Score = 32.7 bits (73), Expect = 2.1
 Identities = 38/180 (21%), Positives = 72/180 (40%), Gaps = 17/180 (9%)

Query: 696 ESGLESTEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIVPASFSC--EAAQTKVTF 753
           + GLE  E     E  L S   +        +  EKK   + +    SC    A + +  
Sbjct: 191 KDGLEDKETALSEELELHSAPSSLPTPNGIQLEAEKKAFSENLDPEDSCLTSLASSSLKQ 250

Query: 754 LIGDSMSPDSDTELRSQAVVDQITRHHTKPLKEER-----------GAIDQHQETKQTTK 802
           ++GDS SP S+     +   ++IT +H     +E             A+++ +E++ T  
Sbjct: 251 ILGDSFSPGSEGNASGKDPNEEITENHNSLKSDENKENSFSADHVTTAVEKSKESQVTAD 310

Query: 803 DQSGESDTQNMVSEEPCEL-PCWNHSDPESMSLFDEYFNDDSIETRTIDDVPFKTSTDSK 861
           D   E     ++ ++   + P  + S    +S      +  +IE R I +   K ST+++
Sbjct: 311 DLEEEKAKAELIMDDDRTVDPLLSKSQSILISTSATASSKKTIEDRNIKN---KKSTNNR 367


>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
          Length = 1441

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 20/86 (23%)

Query: 762  DSDTELRSQAVVDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCEL 821
            DSDT+  S+    ++ RH ++P+++ R    +  + K +  D+  ES+  +  SE     
Sbjct: 1138 DSDTDFCSR----RLRRHPSRPMRQSRRLRRKTPKKKYSDDDEEEESEENSRDSE----- 1188

Query: 822  PCWNHSDPESMSLFDEYFNDDSIETR 847
                       S F + F+DD +ETR
Sbjct: 1189 -----------SDFSDDFSDDFVETR 1203


>gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]
          Length = 1251

 Score = 31.6 bits (70), Expect = 4.6
 Identities = 33/118 (27%), Positives = 46/118 (38%), Gaps = 10/118 (8%)

Query: 619 GQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENAVDVKQYRDKLRTCFD-AK 677
           G N       E E   N +     + D+ ++ S  +  E+ A      R  LR   D A 
Sbjct: 367 GHNNPKKGDAEPESPDNGTSNTSMLEDDLKLSSDEEENEQQAAQ----RTALRALSDSAV 422

Query: 678 LETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHT-GKAMRSTGMVVEKKPP 734
           ++   C  SVP  K + S S   S+  +  SE    SDS T   +  S G     KPP
Sbjct: 423 VQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEG----SKPP 476


>gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]
          Length = 1226

 Score = 31.6 bits (70), Expect = 4.6
 Identities = 33/118 (27%), Positives = 46/118 (38%), Gaps = 10/118 (8%)

Query: 619 GQNVENISQQEREDIQNSSKELLGISDECQMISPSDCQEENAVDVKQYRDKLRTCFD-AK 677
           G N       E E   N +     + D+ ++ S  +  E+ A      R  LR   D A 
Sbjct: 342 GHNNPKKGDAEPESPDNGTSNTSMLEDDLKLSSDEEENEQQAAQ----RTALRALSDSAV 397

Query: 678 LETVVCTGSVPVDKCALSESGLESTEETWQSEKLLDSDSHT-GKAMRSTGMVVEKKPP 734
           ++   C  SVP  K + S S   S+  +  SE    SDS T   +  S G     KPP
Sbjct: 398 VQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEG----SKPP 451


>gi|154426278 hypothetical protein LOC90523 [Homo sapiens]
          Length = 458

 Score = 31.6 bits (70), Expect = 4.6
 Identities = 36/142 (25%), Positives = 54/142 (38%), Gaps = 4/142 (2%)

Query: 844 IETRTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTCFPQQ 903
           +E + +D+ P KT + SKD+            +  +Q  E C  I+ V QDS        
Sbjct: 225 LEQKALDE-PAKTESVSKDNTLEPPVELYFPAQLRQQTEELCATIDKVLQDSLSMHSSDS 283

Query: 904 DQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVSSYY 963
             R   ++L     K  +    A G E       S  S + +S+    G      V S  
Sbjct: 284 PSRSPKTLLGSDTVKTPTTLPRAAGRETKYANLSSPSSTVSESQLTKPGVIRPVPVKSRI 343

Query: 964 GGEQEDWAEEDEIPFPGSKLIE 985
             ++E   EE   P P SK +E
Sbjct: 344 LLKKE---EEVYEPNPFSKYLE 362


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 31.2 bits (69), Expect = 6.0
 Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 12/76 (15%)

Query: 618 LGQNVENISQQEREDIQN--SSKELLGI-----SDECQMISPS--DCQEENAVDVKQYRD 668
           L +  EN+ Q+++E I N  S +E++ I      +    IS      +++ A DV + + 
Sbjct: 462 LKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQ 521

Query: 669 KLRTCF---DAKLETV 681
           KLRT F   DA LETV
Sbjct: 522 KLRTAFTEKDALLETV 537


>gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13
            [Homo sapiens]
          Length = 5058

 Score = 31.2 bits (69), Expect = 6.0
 Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 7/110 (6%)

Query: 859  DSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQDSCKTC----FPQQDQRDTLSILVP 914
            D KD  C+    KI   +   +++   +   T+P+D+ K C    F   D+      L  
Sbjct: 4084 DLKDMACVTSLIKIYIPQAFLKDSSGSELTYTIPKDTDKACLKGLFQALDENLHQLHLTG 4143

Query: 915  HGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHDMTRQVSSYYG 964
            +G  +++ +++ +    D   N+ S  ALG +ESE   H  T  +S Y G
Sbjct: 4144 YGISDTTLEEVFLMLLQD--SNKKSHIALG-TESELQNHRPTGHLSGYCG 4190


>gi|189083849 delta-aminolevulinic acid dehydratase [Homo sapiens]
          Length = 330

 Score = 31.2 bits (69), Expect = 6.0
 Identities = 23/83 (27%), Positives = 33/83 (39%), Gaps = 16/83 (19%)

Query: 608 CNCKYCSHPLLGQNVENISQQEREDIQNSSKELLGISDE-CQMISPSDCQE--------- 657
           C C Y SH   G   EN + +  E  Q  ++  L  +   CQ+++PSD  +         
Sbjct: 122 CLCPYTSHGHCGLLSENGAFRAEESRQRLAEVALAYAKAGCQVVAPSDMMDGRVEAIKEA 181

Query: 658 ------ENAVDVKQYRDKLRTCF 674
                  N V V  Y  K  +CF
Sbjct: 182 LMAHGLGNRVSVMSYSAKFASCF 204


>gi|208431829 eukaryotic translation initiation factor 2-alpha
           kinase 2 isoform b [Homo sapiens]
          Length = 510

 Score = 30.8 bits (68), Expect = 7.9
 Identities = 33/174 (18%), Positives = 68/174 (39%), Gaps = 22/174 (12%)

Query: 701 STEETWQSEKLLDSDSHTGKAMRSTGMVVEKKPPDKIVPASFSCEAAQTKVTFLIGDSMS 760
           S E + +S+ L      T    +S  +V      +      FS + ++          ++
Sbjct: 167 SEETSVKSDYLSSGSFATTCESQSNSLVTSTLASESSSEGDFSADTSE----------IN 216

Query: 761 PDSDTELRSQAVVDQITRHHTKPLKE--ERGAIDQHQETKQTTKDQSGESDTQNMVSEEP 818
            +SD+   S  +++ +  +  K  +    R  +   +ETK T   +  E + + +   + 
Sbjct: 217 SNSDSLNSSSLLMNGLRNNQRKAKRSLAPRFDLPDMKETKYTVDKRKAEREVKALAKLDH 276

Query: 819 CELP----CWNHSDPESMSLFDEYFNDDSIETRTIDDVPFKTSTDSKDHCCMLE 868
             +     CW+  D      +D   +DDS+E+   D    K S+ SK  C  ++
Sbjct: 277 VNIVHYNGCWDGFD------YDPETSDDSLESSDYDPENSKNSSRSKTKCLFIQ 324


>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
           12B isoform b [Homo sapiens]
          Length = 998

 Score = 30.8 bits (68), Expect = 7.9
 Identities = 42/203 (20%), Positives = 81/203 (39%), Gaps = 14/203 (6%)

Query: 781 TKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFN 840
           ++ ++EE          ++  +D++ ES+T+    ++P      NHS+ ES S   E   
Sbjct: 347 SQEMEEENKESSSSSSEEEEGEDEASESETEKEADKKPEAFV--NHSNSESKSSITEQIP 404

Query: 841 DDSIET------RTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQD 894
             +  T      R      F    + KD         +  T ++   +E     E + +D
Sbjct: 405 APAQNTFSASSARRFSSGLFNKPEEPKDESPSSWRLGLRKTGSHNMLSEVANSREPI-RD 463

Query: 895 SCKTCFPQQDQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHD 954
              + + +      +S L+ + DKE  +K          PR  +S S + + E+ ++  +
Sbjct: 464 RGSSIY-RSSSSPRISALLDNKDKERENKSYISSL---APRKLNSTSDIEEKENRESAVN 519

Query: 955 MTRQVSSYYGGEQEDWAEEDEIP 977
           + R   SY      D A+ +EIP
Sbjct: 520 LVRS-GSYTRQLWRDEAKGNEIP 541


>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
           12B isoform a [Homo sapiens]
          Length = 982

 Score = 30.8 bits (68), Expect = 7.9
 Identities = 42/203 (20%), Positives = 81/203 (39%), Gaps = 14/203 (6%)

Query: 781 TKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEPCELPCWNHSDPESMSLFDEYFN 840
           ++ ++EE          ++  +D++ ES+T+    ++P      NHS+ ES S   E   
Sbjct: 347 SQEMEEENKESSSSSSEEEEGEDEASESETEKEADKKPEAFV--NHSNSESKSSITEQIP 404

Query: 841 DDSIET------RTIDDVPFKTSTDSKDHCCMLEFSKILCTKNNKQNNEFCKCIETVPQD 894
             +  T      R      F    + KD         +  T ++   +E     E + +D
Sbjct: 405 APAQNTFSASSARRFSSGLFNKPEEPKDESPSSWRLGLRKTGSHNMLSEVANSREPI-RD 463

Query: 895 SCKTCFPQQDQRDTLSILVPHGDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGHD 954
              + + +      +S L+ + DKE  +K          PR  +S S + + E+ ++  +
Sbjct: 464 RGSSIY-RSSSSPRISALLDNKDKERENKSYISSL---APRKLNSTSDIEEKENRESAVN 519

Query: 955 MTRQVSSYYGGEQEDWAEEDEIP 977
           + R   SY      D A+ +EIP
Sbjct: 520 LVRS-GSYTRQLWRDEAKGNEIP 541


>gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens]
          Length = 292

 Score = 30.8 bits (68), Expect = 7.9
 Identities = 44/202 (21%), Positives = 72/202 (35%), Gaps = 20/202 (9%)

Query: 759 MSPDSDTELRSQAVVDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEP 818
           M P S + +RS    ++  R++ +P  E  G ++         K +S      +  +  P
Sbjct: 51  MLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLED-----DFLKAKSWNKKFYDYEANMP 105

Query: 819 CELPCWNHSDPESMSLFDEYFNDDSIE------TRTIDDVPFKTSTDSKDHCCMLEFSKI 872
                W HS  +   L+ E F  DS +       +T   V   T    K         K 
Sbjct: 106 DR---WGHSGYK--ELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKK 160

Query: 873 LCTKNNKQNNEFCKCIETVPQDSCKTCFPQQDQRDTLSILVPHGDKESSDKKI----AVG 928
              +++K+  +  K    +  DS      +     T     PH  K+ S KK     A+ 
Sbjct: 161 QKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALF 220

Query: 929 TEWDIPRNESSDSALGDSESED 950
            E +   + S DSA   SE  +
Sbjct: 221 LEAESNTSHSDDSASSSSEESE 242


>gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens]
          Length = 293

 Score = 30.8 bits (68), Expect = 7.9
 Identities = 44/203 (21%), Positives = 72/203 (35%), Gaps = 21/203 (10%)

Query: 759 MSPDSDTELRSQAVVDQITRHHTKPLKEERGAIDQHQETKQTTKDQSGESDTQNMVSEEP 818
           M P S + +RS    ++  R++ +P  E  G ++         K +S      +  +  P
Sbjct: 51  MLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLED-----DFLKAKSWNKKFYDYEANMP 105

Query: 819 CELPCWNHSDPESMSLFDEYFNDDSIE-------TRTIDDVPFKTSTDSKDHCCMLEFSK 871
                W HS  +   L+ E F  DS +        +T   V   T    K         K
Sbjct: 106 DR---WGHSGYK--ELYPEEFETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKK 160

Query: 872 ILCTKNNKQNNEFCKCIETVPQDSCKTCFPQQDQRDTLSILVPHGDKESSDKKI----AV 927
               +++K+  +  K    +  DS      +     T     PH  K+ S KK     A+
Sbjct: 161 KQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPAL 220

Query: 928 GTEWDIPRNESSDSALGDSESED 950
             E +   + S DSA   SE  +
Sbjct: 221 FLEAESNTSHSDDSASSSSEESE 243


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,125,783
Number of Sequences: 37866
Number of extensions: 2051934
Number of successful extensions: 5965
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 5918
Number of HSP's gapped (non-prelim): 78
length of query: 1166
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1053
effective length of database: 13,968,660
effective search space: 14708998980
effective search space used: 14708998980
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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