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Search of human proteins with 12056969
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|12056969 homeobox C8 [Homo sapiens]
(242 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|12056969 homeobox C8 [Homo sapiens] 509 e-145
gi|13273317 homeobox B8 [Homo sapiens] 295 3e-80
gi|15029506 homeobox D8 [Homo sapiens] 278 2e-75
gi|24497556 homeobox A7 [Homo sapiens] 149 2e-36
gi|85068580 homeobox B7 [Homo sapiens] 135 2e-32
gi|4758554 homeobox C6 isoform 1 [Homo sapiens] 131 6e-31
gi|23503237 homeobox B6 [Homo sapiens] 129 2e-30
gi|24497544 homeobox C6 isoform 2 [Homo sapiens] 127 1e-29
gi|13489077 homeobox A6 [Homo sapiens] 119 2e-27
gi|4504469 homeobox B5 [Homo sapiens] 114 1e-25
gi|24497517 homeobox A5 [Homo sapiens] 107 9e-24
gi|11321638 homeobox C5 [Homo sapiens] 103 1e-22
gi|23397672 homeobox D4 [Homo sapiens] 98 7e-21
gi|15029508 homeobox B9 [Homo sapiens] 98 7e-21
gi|24497538 homeobox C4 [Homo sapiens] 96 3e-20
gi|24497540 homeobox C4 [Homo sapiens] 96 3e-20
gi|13273315 homeobox B4 [Homo sapiens] 96 4e-20
gi|194363768 homeobox D9 [Homo sapiens] 94 1e-19
gi|148613882 homeobox A4 [Homo sapiens] 94 1e-19
gi|24497547 homeobox C9 [Homo sapiens] 94 1e-19
gi|24497533 homeobox C10 [Homo sapiens] 93 2e-19
gi|23097236 homeobox A9 [Homo sapiens] 92 5e-19
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens] 91 1e-18
gi|182765442 homeobox A10 isoform a [Homo sapiens] 90 2e-18
gi|24497551 homeobox A10 isoform b [Homo sapiens] 90 2e-18
gi|23510366 homeobox D10 [Homo sapiens] 88 6e-18
gi|10140847 homeobox A2 [Homo sapiens] 88 6e-18
gi|5031761 homeobox A1 isoform a [Homo sapiens] 87 1e-17
gi|19923391 homeobox D3 [Homo sapiens] 80 1e-15
gi|7657166 homeobox C11 [Homo sapiens] 80 1e-15
>gi|12056969 homeobox C8 [Homo sapiens]
Length = 242
Score = 509 bits (1312), Expect = e-145
Identities = 242/242 (100%), Positives = 242/242 (100%)
Query: 1 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASHHVQDFF 60
MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASHHVQDFF
Sbjct: 1 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASHHVQDFF 60
Query: 61 HHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANT 120
HHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANT
Sbjct: 61 HHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANT 120
Query: 121 NSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRI 180
NSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRI
Sbjct: 121 NSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRI 180
Query: 181 EVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEEN 240
EVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEEN
Sbjct: 181 EVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEEN 240
Query: 241 KD 242
KD
Sbjct: 241 KD 242
>gi|13273317 homeobox B8 [Homo sapiens]
Length = 243
Score = 295 bits (754), Expect = 3e-80
Identities = 150/243 (61%), Positives = 180/243 (74%), Gaps = 6/243 (2%)
Query: 1 MSSYFVNPLFSKYKAGESLEPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASHHVQDFF 60
MSSYFVN LFSKYK GESL P YYDC F Q +G +VYGP S FQH S +Q+F+
Sbjct: 1 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPS-SGGSFQHPSQ-IQEFY 58
Query: 61 HHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANT 120
H G S +S + YQQNPC+++CHGD FYGY+ L RQSL+GAQ + +VQY DCK +A +
Sbjct: 59 H-GPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQ-DPDLVQYADCKLAAAS 116
Query: 121 NSSEGQGHLNQNSSPSLMFPWMRPHAP-GRRSGRQTYSRYQTLELEKEFLFNPYLTRKRR 179
E Q+ SP+ +FPWMRP A GRR GRQTYSRYQTLELEKEFLFNPYLTRKRR
Sbjct: 117 GLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRR 176
Query: 180 IEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGAR-DEEKVEEEGNEEEEKEEEEKE 238
IEVSHALGLTERQVKIWFQNRRMKWKKENNKDK P ++ ++E++E++ E + +E +
Sbjct: 177 IEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGD 236
Query: 239 ENK 241
K
Sbjct: 237 AQK 239
>gi|15029506 homeobox D8 [Homo sapiens]
Length = 290
Score = 278 bits (712), Expect = 2e-75
Identities = 157/288 (54%), Positives = 177/288 (61%), Gaps = 52/288 (18%)
Query: 1 MSSYFVNPLFSKYKA--------GESLEPAYYDCRFPQSVGRSHALVYGP----GGSAPG 48
MSSYFVNPL+SKYKA GE++ P YYDC F VG HA G SA G
Sbjct: 1 MSSYFVNPLYSKYKAAAAAAAAAGEAINPTYYDCHFAPEVGGRHAAAAAALQLYGNSAAG 60
Query: 49 FQHASHHV----------------------QDFFHHGTSGISNSGYQQNP---------- 76
F HA Q++FH G G + YQ P
Sbjct: 61 FPHAPPQAHAHPHPSPPPSGTGCGGREGRGQEYFHPG-GGSPAAAYQAAPPPPPHPPPPP 119
Query: 77 ----CS-LSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQ 131
C ++CHG+ +KFYGY+ L RQ ++ QQEA +VQYPDCKSS+ N E HLNQ
Sbjct: 120 PPPPCGGIACHGEPAKFYGYDNLQRQPIFTTQQEAELVQYPDCKSSSG-NIGEDPDHLNQ 178
Query: 132 NSSPSLMFPWMRPHA-PGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTE 190
+SSPS MFPWMRP A PGRR GRQTYSR+QTLELEKEFLFNPYLTRKRRIEVSHAL LTE
Sbjct: 179 SSSPSQMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTE 238
Query: 191 RQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKE 238
RQVKIWFQNRRMKWKKENNKDK P +R E K E E +E EE+ E
Sbjct: 239 RQVKIWFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDRAE 286
>gi|24497556 homeobox A7 [Homo sapiens]
Length = 230
Score = 149 bits (377), Expect = 2e-36
Identities = 105/258 (40%), Positives = 133/258 (51%), Gaps = 53/258 (20%)
Query: 2 SSYFVNPLFSKYKAGESL----EPAYYDCRFPQSVGRSHALVYGPGGSA-----PGFQHA 52
SSY+VN LFSKY AG SL EP C F + RS YG G A PG +
Sbjct: 3 SSYYVNALFSKYTAGASLFQNAEPT--SCSFAPNSQRSG---YGAGAGAFASTVPGLYNV 57
Query: 53 SHHVQDFFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYP 112
+ + G+ Y PC+ Y+ Q++ G
Sbjct: 58 NSPLYQSPFASGYGLGADAYGNLPCA-----------SYD----QNIPGLCS-------- 94
Query: 113 DCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNP 172
D A + EG H + ++PWMR P R+ GRQTY+RYQTLELEKEF FN
Sbjct: 95 DLAKGACDKTDEGALH-GAAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNR 153
Query: 173 YLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGA--------------RD 218
YLTR+RRIE++HAL LTERQ+KIWFQNRRMKWKKE +KD+ P A
Sbjct: 154 YLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKE-HKDEGPTAAAAPEGAVPSAAATAA 212
Query: 219 EEKVEEEGNEEEEKEEEE 236
+K +EE ++EEE++EEE
Sbjct: 213 ADKADEEDDDEEEEDEEE 230
>gi|85068580 homeobox B7 [Homo sapiens]
Length = 217
Score = 135 bits (341), Expect = 2e-32
Identities = 94/246 (38%), Positives = 123/246 (50%), Gaps = 48/246 (19%)
Query: 2 SSYFVNPLFSKYKAGESLE-----PAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASHHV 56
S Y+ N LFSKY A S+ P C F + R YG G A + +
Sbjct: 3 SLYYANTLFSKYPASSSVFATGAFPEQTSCAFASNPQRPG---YGAGSGAS----FAASM 55
Query: 57 QDFFHHG-------TSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYG-----AQQ 104
Q + G +G+ +GY P S + H + F Q+L G + +
Sbjct: 56 QGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMH--CAPF-------EQNLSGVCPGDSAK 106
Query: 105 EASVVQYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLEL 164
A + D +A +N ++PWMR R+ GRQTY+RYQTLEL
Sbjct: 107 AAGAKEQRDSDLAAESNFR--------------IYPWMRSSGTDRKRGRQTYTRYQTLEL 152
Query: 165 EKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEE 224
EKEF +N YLTR+RRIE++H L LTERQ+KIWFQNRRMKWKKE NK PG +++ E
Sbjct: 153 EKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKE-NKTAGPGTTGQDRAEA 211
Query: 225 EGNEEE 230
E EEE
Sbjct: 212 EEEEEE 217
>gi|4758554 homeobox C6 isoform 1 [Homo sapiens]
Length = 235
Score = 131 bits (329), Expect = 6e-31
Identities = 94/261 (36%), Positives = 132/261 (50%), Gaps = 45/261 (17%)
Query: 1 MSSYFVNPLFSKYKAG-ESLEP-------AYYDCRFPQSVGRSHAL--VYGPGGSAPGFQ 50
M+SYF NP S + AG + + P AY R + G + A +Y +P
Sbjct: 1 MNSYFTNPSLSCHLAGGQDVLPNVALNSTAYDPVRHFSTYGAAVAQNRIYSTPFYSPQEN 60
Query: 51 HASHHVQDFFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQ 110
+ + +G SNS YQ+ +C RQ+ G + S+ Q
Sbjct: 61 VVFSSSRGPYDYG----SNSFYQEKDMLSNC--------------RQNTLGHNTQTSIAQ 102
Query: 111 YPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRP--------HAPGRRSGRQTYSRYQTL 162
+ +S +G+ + ++PWM+ + RR GRQ YSRYQTL
Sbjct: 103 --------DFSSEQGRTAPQDQKASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTL 154
Query: 163 ELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENN-KDKLPGARDEEK 221
ELEKEF FN YLTR+RRIE+++AL LTERQ+KIWFQNRRMKWKKE+N L G
Sbjct: 155 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGAT 214
Query: 222 VEEEGNEEEEKEEEEKEENKD 242
+ G +EE++EE E+E+ K+
Sbjct: 215 ADSLGGKEEKREETEEEKQKE 235
>gi|23503237 homeobox B6 [Homo sapiens]
Length = 224
Score = 129 bits (325), Expect = 2e-30
Identities = 100/249 (40%), Positives = 128/249 (51%), Gaps = 39/249 (15%)
Query: 1 MSSYFVNPLFSKYKAG--ESL--EPAYYDCRFPQSVGRSHALVYGPG-GSAPGFQHASHH 55
MSSYFVN F A ES + Y + + R + YGPG G GF +S++
Sbjct: 1 MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPL-RHYPAPYGPGPGQDKGFATSSYY 59
Query: 56 VQDFFHHGTSGISNSGY-QQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDC 114
+ GY + PC +G A FY E +L GA ++ P
Sbjct: 60 PP----------AGGGYGRAAPCD---YGPAPAFYR-EKESACALSGADEQPPFHPEPRK 105
Query: 115 KSSANTNSSEGQGHLNQNSSPSLMFPWMR--------PHAPGRRSGRQTYSRYQTLELEK 166
A S G+ + S+P ++PWM+ P R GRQTY+RYQTLELEK
Sbjct: 106 SDCAQDKSVFGETEEQKCSTP--VYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEK 163
Query: 167 EFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEG 226
EF +N YLTR+RRIE++HAL LTERQ+KIWFQNRRMKWKKE+ KL A +
Sbjct: 164 EFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKES---KLLSAS-----QLSA 215
Query: 227 NEEEEKEEE 235
EEEEK+ E
Sbjct: 216 EEEEEKQAE 224
>gi|24497544 homeobox C6 isoform 2 [Homo sapiens]
Length = 153
Score = 127 bits (318), Expect = 1e-29
Identities = 70/156 (44%), Positives = 95/156 (60%), Gaps = 17/156 (10%)
Query: 96 RQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRP--------HAP 147
RQ+ G + S+ Q + +S +G+ + ++PWM+ +
Sbjct: 6 RQNTLGHNTQTSIAQ--------DFSSEQGRTAPQDQKASIQIYPWMQRMNSHSGVGYGA 57
Query: 148 GRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKE 207
RR GRQ YSRYQTLELEKEF FN YLTR+RRIE+++AL LTERQ+KIWFQNRRMKWKKE
Sbjct: 58 DRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 117
Query: 208 NN-KDKLPGARDEEKVEEEGNEEEEKEEEEKEENKD 242
+N L G + G +EE++EE E+E+ K+
Sbjct: 118 SNLTSTLSGGGGGATADSLGGKEEKREETEEEKQKE 153
>gi|13489077 homeobox A6 [Homo sapiens]
Length = 233
Score = 119 bits (299), Expect = 2e-27
Identities = 96/257 (37%), Positives = 127/257 (49%), Gaps = 57/257 (22%)
Query: 1 MSSYFVNPLF-SKYKAGES-------LEPAYYDC--RFPQSVGRSHALVYGPGGSAPGFQ 50
MSSYFVNP F +G+ L A YD FP S G S S P
Sbjct: 1 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGAS---------SLPDKT 51
Query: 51 HASHHVQDFFHHGTSGISNSGYQQNPCSLSCHG-----DASKFYGYEALPRQSLYGAQQE 105
+ S YQQ+ L+C+ AS FY + L S G+ ++
Sbjct: 52 YT---------------SPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQ 96
Query: 106 ASVVQY----PDCKSSANTNSSEGQGHLNQNSS---PSLMFPWMR--------PHAPGRR 150
Y P+ + +++S +G+ ++ + S ++PWM+ + R
Sbjct: 97 RGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGR 156
Query: 151 SGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKEN-- 208
GRQTY+RYQTLELEKEF FN YLTR+RRIE+++AL LTERQ+KIWFQNRRMKWKKEN
Sbjct: 157 RGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKL 216
Query: 209 -NKDKLPGARDEEKVEE 224
N + G E K E
Sbjct: 217 INSTQPSGEDSEAKAGE 233
>gi|4504469 homeobox B5 [Homo sapiens]
Length = 269
Score = 114 bits (284), Expect = 1e-25
Identities = 92/263 (34%), Positives = 119/263 (45%), Gaps = 65/263 (24%)
Query: 1 MSSYFVNPLFSKYK-----------AGESLEPAYYDCR-------------FPQSVGRSH 36
MSSYFVN +Y +G SL +Y D SV RS
Sbjct: 1 MSSYFVNSFSGRYPNGPDYQLLNYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSS 60
Query: 37 ALV--YGP-GGSAPGFQHASHHVQDFFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEA 93
A +G G S+ F + + F S S S + PC+ +GD+ +
Sbjct: 61 ASSSHFGAVGESSRAFPAPAQEPR--FRQAASSCSLSSPESLPCT---NGDSHGAKPSAS 115
Query: 94 LPRQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQNSSPSL---------------- 137
P A A+ + + +S SE + +Q SSPSL
Sbjct: 116 SPSDQATSASSSANFTEIDEASAS-----SEPEEAASQLSSPSLARAQPEPMATSTAAPE 170
Query: 138 -----MFPWMRP-------HAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHA 185
+FPWMR P + R Y+RYQTLELEKEF FN YLTR+RRIE++HA
Sbjct: 171 GQTPQIFPWMRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHA 230
Query: 186 LGLTERQVKIWFQNRRMKWKKEN 208
L L+ERQ+KIWFQNRRMKWKK+N
Sbjct: 231 LCLSERQIKIWFQNRRMKWKKDN 253
>gi|24497517 homeobox A5 [Homo sapiens]
Length = 270
Score = 107 bits (267), Expect = 9e-24
Identities = 85/256 (33%), Positives = 110/256 (42%), Gaps = 50/256 (19%)
Query: 1 MSSYFVNPLFSKYKAG-----------ESLEPAYYDCR-------------FPQSVGRSH 36
MSSYFVN +Y G S+ + D SVGRS
Sbjct: 1 MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSG 60
Query: 37 ALVYGPGGSAPGFQHASHHVQDFFHHGTSGISNSGYQQNPCSLSC----HGDASKFYGYE 92
+ +G G A + ++ + S Q +P S G S G
Sbjct: 61 SGHFGSGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLPCSAVAPSPGSDSHHGGKN 120
Query: 93 ALPRQSLYGAQQEASVVQYPD-----CKSSANTNSSEGQGHLNQNSSPS-------LMFP 140
+L S GA +A S A ++ + S PS ++P
Sbjct: 121 SLSNSS--GASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYP 178
Query: 141 WMRP--------HAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQ 192
WMR P + R Y+RYQTLELEKEF FN YLTR+RRIE++HAL L+ERQ
Sbjct: 179 WMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQ 238
Query: 193 VKIWFQNRRMKWKKEN 208
+KIWFQNRRMKWKK+N
Sbjct: 239 IKIWFQNRRMKWKKDN 254
>gi|11321638 homeobox C5 [Homo sapiens]
Length = 222
Score = 103 bits (257), Expect = 1e-22
Identities = 57/125 (45%), Positives = 74/125 (59%), Gaps = 8/125 (6%)
Query: 92 EALPRQSLYGAQQEASVVQYPDCKSSANTNSSEGQ----GHLNQNSSPSLMFPWMRP--- 144
EA P +Q+ A KSS + Q L+Q +P ++PWM
Sbjct: 90 EAAPLNPGMYSQKAARPALEERAKSSGEIKEEQAQTGQPAGLSQPPAPPQIYPWMTKLHM 149
Query: 145 -HAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMK 203
H + R +Y+RYQTLELEKEF FN YLTR+RRIE+++ L L ERQ+KIWFQNRRMK
Sbjct: 150 SHETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMK 209
Query: 204 WKKEN 208
WKK++
Sbjct: 210 WKKDS 214
>gi|23397672 homeobox D4 [Homo sapiens]
Length = 255
Score = 97.8 bits (242), Expect = 7e-21
Identities = 79/231 (34%), Positives = 112/231 (48%), Gaps = 28/231 (12%)
Query: 1 MSSYFVNPLFSKYKAGESLEPAYYDCR-FPQS--VGRSHALVYGPGGSAPGFQHASHHVQ 57
MSSY VN SKY ++P + C + Q +G A YG G FQ + +
Sbjct: 3 MSSYMVN---SKY-----VDPKFPPCEEYLQGGYLGEQGADYYGGGAQGADFQPPGLYPR 54
Query: 58 DFFHHGTSGISNSGYQQNPCSLSCHG-DASKFYGYEALPRQSLYGAQQEASVVQYPDCKS 116
F G S G + HG + G+ A P + A P ++
Sbjct: 55 PDFGEQPFGGSGPG-PGSALPARGHGQEPGGPGGHYAAPGEPC-PAPPAPPPAPLPGARA 112
Query: 117 SANTNSSEGQGHLNQNSSPSLMFPWMR--------PHAPGR--RSGRQTYSRYQTLELEK 166
+ ++ + P++++PWM+ P+ G + R Y+R Q LELEK
Sbjct: 113 YSQSDPKQPPSG-TALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEK 171
Query: 167 EFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGAR 217
EF FN YLTR+RRIE++H L L+ERQ+KIWFQNRRMKWKK++ KLP +
Sbjct: 172 EFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDH---KLPNTK 219
>gi|15029508 homeobox B9 [Homo sapiens]
Length = 250
Score = 97.8 bits (242), Expect = 7e-21
Identities = 83/243 (34%), Positives = 115/243 (47%), Gaps = 36/243 (14%)
Query: 1 MSSYFVNPLFS---------KYKAGE---SLEPAYYD-CRFPQSVGRSHALVYGPGGSAP 47
+SSY+V+ + S K+ +G+ S +P + + FP + A V+G AP
Sbjct: 7 LSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASW-AP 65
Query: 48 GFQHASHHVQDFFHH--GTSGI--SNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQ 103
HAS + +H G+ + S Y + + G+A+ G A+ + L GA
Sbjct: 66 LSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAP 125
Query: 104 QEASVVQYPDC-------KSSANTNSSEGQGH------LNQNSSPSLMFP---WMRPHAP 147
E P+ + + +N G G P P W+ HA
Sbjct: 126 GELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWL--HAR 183
Query: 148 GRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKE 207
R R Y++YQTLELEKEFLFN YLTR RR EV+ L L+ERQVKIWFQNRRMK KK
Sbjct: 184 SSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKM 243
Query: 208 NNK 210
N +
Sbjct: 244 NKE 246
>gi|24497538 homeobox C4 [Homo sapiens]
Length = 264
Score = 95.9 bits (237), Expect = 3e-20
Identities = 75/236 (31%), Positives = 107/236 (45%), Gaps = 41/236 (17%)
Query: 1 MSSYFVNPLF---SKYKAGESL---EPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASH 54
M S +++P F +Y + P YY H +Y P P + +
Sbjct: 8 MDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQY 67
Query: 55 HVQDFFHHGTS---GISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQY 111
G S G + +G+ S S + + G A P + Q A
Sbjct: 68 SCTSLQGPGNSRGHGPAQAGHHHPEKSQSLC-EPAPLSGASASPSPAPPACSQPA----- 121
Query: 112 PDCKSSANTNSSEGQGHLNQNSSPSLMFPWMR--------PHAPGR--RSGRQTYSRYQT 161
PD SSA S +++PWM+ P+ G + R Y+R Q
Sbjct: 122 PDHPSSAA-------------SKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQV 168
Query: 162 LELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGAR 217
LELEKEF +N YLTR+RRIE++H+L L+ERQ+KIWFQNRRMKWKK++ +LP +
Sbjct: 169 LELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDH---RLPNTK 221
>gi|24497540 homeobox C4 [Homo sapiens]
Length = 264
Score = 95.9 bits (237), Expect = 3e-20
Identities = 75/236 (31%), Positives = 107/236 (45%), Gaps = 41/236 (17%)
Query: 1 MSSYFVNPLF---SKYKAGESL---EPAYYDCRFPQSVGRSHALVYGPGGSAPGFQHASH 54
M S +++P F +Y + P YY H +Y P P + +
Sbjct: 8 MDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQY 67
Query: 55 HVQDFFHHGTS---GISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQY 111
G S G + +G+ S S + + G A P + Q A
Sbjct: 68 SCTSLQGPGNSRGHGPAQAGHHHPEKSQSLC-EPAPLSGASASPSPAPPACSQPA----- 121
Query: 112 PDCKSSANTNSSEGQGHLNQNSSPSLMFPWMR--------PHAPGR--RSGRQTYSRYQT 161
PD SSA S +++PWM+ P+ G + R Y+R Q
Sbjct: 122 PDHPSSAA-------------SKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQV 168
Query: 162 LELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGAR 217
LELEKEF +N YLTR+RRIE++H+L L+ERQ+KIWFQNRRMKWKK++ +LP +
Sbjct: 169 LELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDH---RLPNTK 221
>gi|13273315 homeobox B4 [Homo sapiens]
Length = 251
Score = 95.5 bits (236), Expect = 4e-20
Identities = 48/91 (52%), Positives = 64/91 (70%), Gaps = 13/91 (14%)
Query: 137 LMFPWMRP---------HAPGR-RSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHAL 186
+++PWMR +A G + R Y+R Q LELEKEF +N YLTR+RR+E++HAL
Sbjct: 140 VVYPWMRKVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHAL 199
Query: 187 GLTERQVKIWFQNRRMKWKKENNKDKLPGAR 217
L+ERQ+KIWFQNRRMKWKK++ KLP +
Sbjct: 200 CLSERQIKIWFQNRRMKWKKDH---KLPNTK 227
>gi|194363768 homeobox D9 [Homo sapiens]
Length = 352
Score = 94.0 bits (232), Expect = 1e-19
Identities = 56/105 (53%), Positives = 66/105 (62%), Gaps = 8/105 (7%)
Query: 112 PDC--KSSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFL 169
P C K +S Q L+ N+ + W+ HA R R Y++YQTLELEKEFL
Sbjct: 251 PGCSLKEEEKQHSQPQQQQLDPNNPAA---NWI--HARSTRKKRCPYTKYQTLELEKEFL 305
Query: 170 FNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLP 214
FN YLTR RR EV+ L LTERQVKIWFQNRRMK KK +K+K P
Sbjct: 306 FNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKK-MSKEKCP 349
>gi|148613882 homeobox A4 [Homo sapiens]
Length = 320
Score = 93.6 bits (231), Expect = 1e-19
Identities = 50/91 (54%), Positives = 62/91 (68%), Gaps = 13/91 (14%)
Query: 137 LMFPWMRP-HA----PGRRSG-----RQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHAL 186
+++PWM+ H P G R Y+R Q LELEKEF FN YLTR+RRIE++H L
Sbjct: 193 VVYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTL 252
Query: 187 GLTERQVKIWFQNRRMKWKKENNKDKLPGAR 217
L+ERQVKIWFQNRRMKWKK++ KLP +
Sbjct: 253 CLSERQVKIWFQNRRMKWKKDH---KLPNTK 280
>gi|24497547 homeobox C9 [Homo sapiens]
Length = 260
Score = 93.6 bits (231), Expect = 1e-19
Identities = 51/99 (51%), Positives = 64/99 (64%), Gaps = 5/99 (5%)
Query: 112 PDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFN 171
P+ + A + E + L+ ++ + W+ HA R R Y++YQTLELEKEFLFN
Sbjct: 160 PEADALAGSKHKEEKADLDPSNPVA---NWI--HARSTRKKRCPYTKYQTLELEKEFLFN 214
Query: 172 PYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNK 210
YLTR RR EV+ L LTERQVKIWFQNRRMK KK N +
Sbjct: 215 MYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKE 253
>gi|24497533 homeobox C10 [Homo sapiens]
Length = 342
Score = 92.8 bits (229), Expect = 2e-19
Identities = 49/113 (43%), Positives = 72/113 (63%), Gaps = 5/113 (4%)
Query: 101 GAQQEASVVQYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQ 160
G+ E+ + SS +T+ +E + + ++ W+ A R R Y+++Q
Sbjct: 225 GSPSESEKERAKAADSSPDTSDNEAKEEIKAENTTG---NWLT--AKSGRKKRCPYTKHQ 279
Query: 161 TLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKL 213
TLELEKEFLFN YLTR+RR+E+S + LT+RQVKIWFQNRRMK KK N ++++
Sbjct: 280 TLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRI 332
>gi|23097236 homeobox A9 [Homo sapiens]
Length = 272
Score = 91.7 bits (226), Expect = 5e-19
Identities = 50/75 (66%), Positives = 56/75 (74%), Gaps = 4/75 (5%)
Query: 145 HAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKW 204
HA R R Y+++QTLELEKEFLFN YLTR RR EV+ L LTERQVKIWFQNRRMK
Sbjct: 202 HARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKM 261
Query: 205 KKENNKDKLPGARDE 219
KK NKD+ A+DE
Sbjct: 262 KK-INKDR---AKDE 272
>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
Length = 283
Score = 90.5 bits (223), Expect = 1e-18
Identities = 50/103 (48%), Positives = 64/103 (62%), Gaps = 17/103 (16%)
Query: 127 GHLNQNSSPSLMFPWMRP---HA-PGRRSG-------------RQTYSRYQTLELEKEFL 169
G L + + L FPWM+ HA G+ +G R Y+R Q LELEKEFL
Sbjct: 107 GVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFL 166
Query: 170 FNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDK 212
FN Y++R RR+E++ L LTER +KIWFQNRRMKWKKE +K +
Sbjct: 167 FNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKR 209
>gi|182765442 homeobox A10 isoform a [Homo sapiens]
Length = 410
Score = 90.1 bits (222), Expect = 2e-18
Identities = 59/141 (41%), Positives = 80/141 (56%), Gaps = 18/141 (12%)
Query: 76 PCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANTNS---SEGQGHLNQN 132
P +L+C G G E S A +E S K+S +S S+G+ N
Sbjct: 275 PPTLAC-GSGGGSQGDEEAHASS--SAAEELSPAPSESSKASPEKDSLGNSKGENAAN-- 329
Query: 133 SSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQ 192
W+ A R R Y+++QTLELEKEFLFN YLTR+RR+E+S ++ LT+RQ
Sbjct: 330 --------WLT--AKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQ 379
Query: 193 VKIWFQNRRMKWKKENNKDKL 213
VKIWFQNRRMK KK N ++++
Sbjct: 380 VKIWFQNRRMKLKKMNRENRI 400
>gi|24497551 homeobox A10 isoform b [Homo sapiens]
Length = 94
Score = 89.7 bits (221), Expect = 2e-18
Identities = 42/68 (61%), Positives = 55/68 (80%)
Query: 146 APGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWK 205
A R R Y+++QTLELEKEFLFN YLTR+RR+E+S ++ LT+RQVKIWFQNRRMK K
Sbjct: 17 AKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLK 76
Query: 206 KENNKDKL 213
K N ++++
Sbjct: 77 KMNRENRI 84
>gi|23510366 homeobox D10 [Homo sapiens]
Length = 340
Score = 88.2 bits (217), Expect = 6e-18
Identities = 41/68 (60%), Positives = 55/68 (80%)
Query: 146 APGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWK 205
A R R Y+++QTLELEKEFLFN YLTR+RR+E+S ++ LT+RQVKIWFQNRRMK K
Sbjct: 263 AKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLK 322
Query: 206 KENNKDKL 213
K + ++++
Sbjct: 323 KMSRENRI 330
>gi|10140847 homeobox A2 [Homo sapiens]
Length = 376
Score = 88.2 bits (217), Expect = 6e-18
Identities = 49/92 (53%), Positives = 59/92 (64%), Gaps = 10/92 (10%)
Query: 148 GRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKK- 206
G R R Y+ Q LELEKEF FN YL R RR+E++ L LTERQVK+WFQNRRMK K+
Sbjct: 142 GSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 201
Query: 207 ------ENNKDKLPGARDEEKVEEEGNEEEEK 232
+N++ K D EKVEE +EEEK
Sbjct: 202 TQCKENQNSEGKCKSLEDSEKVEE---DEEEK 230
>gi|5031761 homeobox A1 isoform a [Homo sapiens]
Length = 335
Score = 87.0 bits (214), Expect = 1e-17
Identities = 68/216 (31%), Positives = 93/216 (43%), Gaps = 43/216 (19%)
Query: 39 VYGPGGSAPGFQHASHHVQDFFHHGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQS 98
VY S+P QH HH + + + Y + A Y P
Sbjct: 130 VYSGNLSSPMVQHHHHHQG----YAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSP--- 182
Query: 99 LYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSG------ 152
L+ + QEA C+S A+ + SSP+ F WM+ ++G
Sbjct: 183 LHASHQEA-------CRSPAS-----------ETSSPAQTFDWMKVKRNPPKTGKVGEYG 224
Query: 153 --------RQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKW 204
R ++ Q ELEKEF FN YLTR RR+E++ +L L E QVKIWFQNRRMK
Sbjct: 225 YLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQ 284
Query: 205 KKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEEN 240
KK + LP GN+E+ +E EK +
Sbjct: 285 KKREKEGLLP----ISPATPPGNDEKAEESSEKSSS 316
>gi|19923391 homeobox D3 [Homo sapiens]
Length = 432
Score = 80.5 bits (197), Expect = 1e-15
Identities = 50/129 (38%), Positives = 66/129 (51%), Gaps = 33/129 (25%)
Query: 112 PDCKSSANTNSSEG------QGHLNQNSSPSLM----FPWMR------------------ 143
P S+ TN G +G N +SS + + FPWM+
Sbjct: 124 PTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATAGES 183
Query: 144 -----PHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQ 198
P P + R Y+ Q +ELEKEF FN YL R RR+E+++ L LTERQ+KIWFQ
Sbjct: 184 CEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ 243
Query: 199 NRRMKWKKE 207
NRRMK+KK+
Sbjct: 244 NRRMKYKKD 252
>gi|7657166 homeobox C11 [Homo sapiens]
Length = 304
Score = 80.5 bits (197), Expect = 1e-15
Identities = 51/132 (38%), Positives = 67/132 (50%), Gaps = 9/132 (6%)
Query: 76 PCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANTN-SSEGQGHLNQNSS 134
P C G EA P L + + + + NTN SS G H S
Sbjct: 166 PAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEAEE----ENTNPSSSGSAH----SV 217
Query: 135 PSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVK 194
P+AP R R YS++Q ELE+EF FN Y+ +++R+++S L LT+RQVK
Sbjct: 218 AKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVK 277
Query: 195 IWFQNRRMKWKK 206
IWFQNRRMK KK
Sbjct: 278 IWFQNRRMKEKK 289
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,486,505
Number of Sequences: 37866
Number of extensions: 609205
Number of successful extensions: 16603
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 724
Number of HSP's successfully gapped in prelim test: 134
Number of HSP's that attempted gapping in prelim test: 6572
Number of HSP's gapped (non-prelim): 6092
length of query: 242
length of database: 18,247,518
effective HSP length: 99
effective length of query: 143
effective length of database: 14,498,784
effective search space: 2073326112
effective search space used: 2073326112
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.