Guide to the Human Genome
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Search of human proteins with 247301334

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|247301334 non-protein coding RNA 153 isoform 3 [Homo
sapiens]
         (540 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|247301334 non-protein coding RNA 153 isoform 3 [Homo sapiens]     1077   0.0  
gi|247301318 non-protein coding RNA 153 isoform 2 [Homo sapiens]     1074   0.0  
gi|118150654 non-protein coding RNA 153 isoform 1 [Homo sapiens]     1074   0.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    49   2e-05
gi|33356174 pinin, desmosome associated protein [Homo sapiens]         45   1e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     44   3e-04
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    43   6e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    43   6e-04
gi|54633319 PDZ domain-containing guanine nucleotide exchange fa...    43   8e-04
gi|20336260 retinoblastoma protein-binding zinc finger protein i...    41   0.002
gi|20336258 retinoblastoma protein-binding zinc finger protein i...    41   0.002
gi|148806891 hypothetical protein LOC54906 [Homo sapiens]              40   0.005
gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens]         39   0.009
gi|34996489 pleckstrin homology domain interacting protein [Homo...    39   0.016
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          39   0.016
gi|21396500 HIRA interacting protein 3 [Homo sapiens]                  38   0.027
gi|190194423 SPARC-like 1 [Homo sapiens]                               37   0.035
gi|190341024 SPARC-like 1 [Homo sapiens]                               37   0.035
gi|210032580 SET domain containing 1B [Homo sapiens]                   37   0.046
gi|17978469 cyclin T2 isoform b [Homo sapiens]                         36   0.078
gi|154090979 hypothetical protein LOC57481 [Homo sapiens]              36   0.078
gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens]         36   0.10 
gi|4502805 chromogranin A precursor [Homo sapiens]                     36   0.10 
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          36   0.10 
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          36   0.10 
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          36   0.10 
gi|55953110 retinoblastoma protein-binding zinc finger protein i...    35   0.13 
gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens]     35   0.13 
gi|38176300 nestin [Homo sapiens]                                      35   0.17 
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]        35   0.23 

>gi|247301334 non-protein coding RNA 153 isoform 3 [Homo sapiens]
          Length = 540

 Score = 1077 bits (2786), Expect = 0.0
 Identities = 540/540 (100%), Positives = 540/540 (100%)

Query: 1   MQVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHS 60
           MQVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHS
Sbjct: 1   MQVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHS 60

Query: 61  HRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLE 120
           HRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLE
Sbjct: 61  HRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLE 120

Query: 121 IGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEE 180
           IGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEE
Sbjct: 121 IGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEE 180

Query: 181 KRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWS 240
           KRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWS
Sbjct: 181 KRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWS 240

Query: 241 TSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQT 300
           TSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQT
Sbjct: 241 TSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQT 300

Query: 301 LSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTE 360
           LSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTE
Sbjct: 301 LSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTE 360

Query: 361 ECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVA 420
           ECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVA
Sbjct: 361 ECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVA 420

Query: 421 ADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIAS 480
           ADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIAS
Sbjct: 421 ADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIAS 480

Query: 481 EASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD 540
           EASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD
Sbjct: 481 EASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD 540


>gi|247301318 non-protein coding RNA 153 isoform 2 [Homo sapiens]
          Length = 570

 Score = 1074 bits (2777), Expect = 0.0
 Identities = 538/539 (99%), Positives = 539/539 (100%)

Query: 2   QVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSH 61
           +VAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSH
Sbjct: 32  KVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSH 91

Query: 62  RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEI 121
           RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEI
Sbjct: 92  RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEI 151

Query: 122 GSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEK 181
           GSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEK
Sbjct: 152 GSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEK 211

Query: 182 RASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWST 241
           RASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWST
Sbjct: 212 RASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWST 271

Query: 242 SSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTL 301
           SSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTL
Sbjct: 272 SSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTL 331

Query: 302 SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE 361
           SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE
Sbjct: 332 SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE 391

Query: 362 CGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAA 421
           CGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAA
Sbjct: 392 CGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAA 451

Query: 422 DIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASE 481
           DIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASE
Sbjct: 452 DIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASE 511

Query: 482 ASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD 540
           ASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD
Sbjct: 512 ASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD 570


>gi|118150654 non-protein coding RNA 153 isoform 1 [Homo sapiens]
          Length = 673

 Score = 1074 bits (2777), Expect = 0.0
 Identities = 538/539 (99%), Positives = 539/539 (100%)

Query: 2   QVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSH 61
           +VAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSH
Sbjct: 135 KVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSH 194

Query: 62  RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEI 121
           RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEI
Sbjct: 195 RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEI 254

Query: 122 GSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEK 181
           GSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEK
Sbjct: 255 GSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEK 314

Query: 182 RASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWST 241
           RASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWST
Sbjct: 315 RASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWST 374

Query: 242 SSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTL 301
           SSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTL
Sbjct: 375 SSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTL 434

Query: 302 SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE 361
           SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE
Sbjct: 435 SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE 494

Query: 362 CGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAA 421
           CGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAA
Sbjct: 495 CGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAA 554

Query: 422 DIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASE 481
           DIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASE
Sbjct: 555 DIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASE 614

Query: 482 ASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD 540
           ASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD
Sbjct: 615 ASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD 673


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 91/505 (18%), Positives = 178/505 (35%), Gaps = 39/505 (7%)

Query: 39   DFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQ 98
            D S  + S     + S     S   ++ SSN +DS     S+D+   + SD+ D K+   
Sbjct: 570  DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS--DSSDSSDSKSDSS 627

Query: 99   IGEKMPVTASVLSEEEQTHCLEIGSNT-RHGKSNLSEGKKSAELNSPLRERLSPENRTTD 157
              E     +   S+   ++  +   N+     SN S    S++ +       S ++  + 
Sbjct: 628  KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687

Query: 158  LKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHL 217
               DSS  S             E   S   S    S+  +S N  S +  S     S   
Sbjct: 688  DSSDSSDSSNS----------SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737

Query: 218  AHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEA 277
            ++    S         +  +S  +S+    S S D           +        D  ++
Sbjct: 738  SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797

Query: 278  LKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVA 337
                 +     +  +  +    + +S DS   S ++  +     +  SD   +  G    
Sbjct: 798  SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD---SSDGSDSD 854

Query: 338  TLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLN 397
            +    D+S   +++     + + +    S   S+ESS S  S  + NS   ++      +
Sbjct: 855  SSNRSDSSNSSDSSDSSDSSNSSDSSDSS--DSNESSNSSDSSDSSNSSDSDSS-----D 907

Query: 398  SVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASV 457
            S  + +   SS   D S+  N +                +   D++N +++      ++ 
Sbjct: 908  SSNSSDSSDSSNSSDSSESSNSS--------------DNSNSSDSSNSSDSSDSSDSSNS 953

Query: 458  SHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESD-- 515
            S  S  +  S + ++  +N   S  S +SS+ S  S   +      +  S+   D SD  
Sbjct: 954  SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013

Query: 516  DSNSEIEAALRPRNHNTDDSDDFYD 540
            DS++  +++    + N+ DS D  D
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSD 1038



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 89/505 (17%), Positives = 176/505 (34%), Gaps = 18/505 (3%)

Query: 39   DFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQ 98
            D S    S     + +  D      ++ SSN +DS     S+D+   N SD+ +   S  
Sbjct: 775  DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD 834

Query: 99   IGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDL 158
                   + S  S +      +  S+ R   SN S+   S++ ++      S ++  +  
Sbjct: 835  SSNSSDSSDSSDSSDGS----DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890

Query: 159  KCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLA 218
              DSS  S     + +    +   +S        S+  ES N       S     SD   
Sbjct: 891  SSDSSDSSN----SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD--- 943

Query: 219  HREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEAL 278
                 S               S SSD + S S D     +     +     +  D  ++ 
Sbjct: 944  --SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001

Query: 279  KLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVAT 338
                +     +  +  +      S   +  +SS ++ + +   + DS           ++
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061

Query: 339  LKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSI-LNDNSGIKEAKPAVWLN 397
                 +   + + +      +E      + +SS+SS S  S   +D+S   ++  +   +
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS--SD 1119

Query: 398  SVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASV 457
            S  + +   SS   D S   N +     +E+        ++   +++ + +    +D+S 
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1179

Query: 458  SHLSGLNIGSGAFETKTANKIASEASFS--SSEGSPLSRHENKKKPVINLKSNALWDESD 515
            S  S  +  S      + +  +S++S S  SS+ S  S   +      +  SN   D SD
Sbjct: 1180 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSD 1239

Query: 516  DSNSEIEAALRPRNHNTDDSDDFYD 540
             S+S   +     + ++D SD   D
Sbjct: 1240 SSDSSDSSNSSDSSDSSDSSDSTSD 1264



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 83/500 (16%), Positives = 182/500 (36%), Gaps = 26/500 (5%)

Query: 41   STEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQ----CLNKSDNIDGKAS 96
            S++  S   + N    D  +   ++ SS+ +DS    +S+D+       + SD+ +   S
Sbjct: 642  SSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701

Query: 97   LQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTT 156
                +     +S  S+   ++  +  S+     S+ S    S++ +       S ++  +
Sbjct: 702  SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 761

Query: 157  DLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDH 216
                DSS  S+    +      +   +S        S+  +S N       S     SD 
Sbjct: 762  SNSSDSSDSSDSSDSS------DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS 815

Query: 217  LAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIE 276
                   S          +  + S SSD + S    D    +     N     +  D   
Sbjct: 816  SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875

Query: 277  ALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHV 336
            +     +     + ++  +    + +S DS+   S+N+       +  SD   +      
Sbjct: 876  SSDSSDSSDSNESSNSSDSS--DSSNSSDSDSSDSSNS-------SDSSDSSNSSDSSES 926

Query: 337  ATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWL 396
            +   ++ NS  + + +      ++      + +SS+SS S  S  +++S   ++      
Sbjct: 927  SNSSDNSNS-SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS----- 980

Query: 397  NSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDAS 456
            NS  + +   SS   D S   N +     +++        ++   +++ + +    +D+S
Sbjct: 981  NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040

Query: 457  VSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDD 516
             S  S  +  S      + +  +S++S  SS+ S  S   +  +   +  S+   D SD 
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSS-DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099

Query: 517  SNSEIEAALRPRNHNTDDSD 536
            S+S   +     + ++D SD
Sbjct: 1100 SDSSDSSDSSDSSDSSDSSD 1119



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 85/496 (17%), Positives = 174/496 (35%), Gaps = 22/496 (4%)

Query: 41   STEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIG 100
            S++      + + S     S  ++  S + +DS    + +D+   N SD+ D   S    
Sbjct: 601  SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660

Query: 101  EKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKC 160
                 + S  S +         S+     S+ S+   S+E +       S  + ++D   
Sbjct: 661  NSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN 720

Query: 161  DSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHR 220
             +SS S+    +          +S        S+  +S +  +    S     SD  +  
Sbjct: 721  SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD--SSD 778

Query: 221  EPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKL 280
               S          +    S SSD + S    D    S     N        D  ++   
Sbjct: 779  SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS--- 835

Query: 281  IHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLK 340
             ++     +  +       + +  DS   S ++  +     +  SD   +    + +   
Sbjct: 836  SNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895

Query: 341  EHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVP 400
            +  NS   +++     + + +    S   SSESS S     +DNS   ++      NS  
Sbjct: 896  DSSNSSDSDSSDSSNSSDSSDSSNSS--DSSESSNS-----SDNSNSSDSS-----NSSD 943

Query: 401  TREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHL 460
            + +   SS   D S   + +     +++ +      +   D+++ +++    +D+S S  
Sbjct: 944  SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS----SDSSDSSD 999

Query: 461  SGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSE 520
            S  N    +  + +++   S  S +SS+ S  S   +      +  S+   D SD SNS 
Sbjct: 1000 SS-NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058

Query: 521  IEAALRPRNHNTDDSD 536
              +     + ++D SD
Sbjct: 1059 DSSDSSDSSDSSDSSD 1074



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 88/504 (17%), Positives = 179/504 (35%), Gaps = 17/504 (3%)

Query: 41   STEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIG 100
            S++  +   + N S     S    + SSN +DS     S+D+   N SD+ D   S    
Sbjct: 794  SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS--NSSDSSDSSDSSDGS 851

Query: 101  EKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLK- 159
            +      S  S    +      SN+    S+ S+  +S+  +       S ++ ++D   
Sbjct: 852  DSDSSNRSDSSNSSDSSDSSDSSNSSDS-SDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910

Query: 160  -CDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLA 218
              DSS  S     +      +   +S   +    S+  +S N       S     SD   
Sbjct: 911  SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970

Query: 219  HREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEAL 278
                 S          +    S SSD + S +  D    S +   +       +    + 
Sbjct: 971  SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD----SSDSSDSSDSSNSSDSSNSSD 1026

Query: 279  KLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVAT 338
                ++    + S++ +    +  S DS   S ++  +     +  SD   +      + 
Sbjct: 1027 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSD 1086

Query: 339  LKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNS 398
              +  NS     ++    +        S+  S  S+ S  S  +D+S   ++  +   +S
Sbjct: 1087 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS--DS 1144

Query: 399  VPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVS 458
              + E   SS   D S   + +     +++        ++   +++ + +    +D+S S
Sbjct: 1145 SDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1204

Query: 459  HLSGLNIGSGAFETKTANKIASEASFS-----SSEGSPLSRHENKKKPVINL-KSNALWD 512
              S  +  S      + +  +S++S S     SS+ S  S   N      +   S++  D
Sbjct: 1205 SDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSD 1264

Query: 513  ESDDSNSEIEAALRPRNHNTDDSD 536
             +D+S+S+ ++     N +  DSD
Sbjct: 1265 SNDESDSQSKSGNGNNNGSDSDSD 1288


>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
          Length = 717

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 80/370 (21%), Positives = 143/370 (38%), Gaps = 38/370 (10%)

Query: 167 EGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQK 226
           EG++  RE  E+EE       + + + E  E E K     HS  E               
Sbjct: 309 EGKVAQREE-ELEE--TGNQHNDVEIEEAGEEEEKEIAIVHSDAE--------------- 350

Query: 227 PFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPN-PGGKMEGEDGIEALKLIHAEQ 285
              K QEEEE+      ++ + + E+  + ES + Q + P   M+  + +E +K + A+Q
Sbjct: 351 ---KEQEEEEQK----QEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQ 403

Query: 286 ERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVG-QHVATLK-EHD 343
           E +  +  ++        P   + S    P  E    PD +      G ++V+ L  E +
Sbjct: 404 EVMETNRVESV------EPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKE 457

Query: 344 NSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTRE 403
           +  KEE  +  +     +   +S       S S P + +      E      L   P   
Sbjct: 458 SEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVT 517

Query: 404 QEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGL 463
           QE   G     +K+     + +TE     +L      ++ ++T+ R +    + +  S  
Sbjct: 518 QE--QGHLLPERKDFPVESVKLTEVPVEPVL--TVHPESKSKTKTRSRSRGRARNKTSKS 573

Query: 464 NIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEA 523
              S +  + +++  +S +  SSS GS  SR  +      +  S+     S  S+SE  +
Sbjct: 574 RSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRS 633

Query: 524 ALRPRNHNTD 533
             R R HN D
Sbjct: 634 RSRGRGHNRD 643


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 65/289 (22%), Positives = 117/289 (40%), Gaps = 44/289 (15%)

Query: 92  DGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERL-- 149
           + K+ ++   K P  A    +EE     E+ S  +       E K   E  SP +E    
Sbjct: 515 EAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKS 574

Query: 150 -----SPENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQ 204
                SPE   +  K ++ S +E +   +    V+E+  SP  +  PV E    E K   
Sbjct: 575 PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE----EAKSPA 630

Query: 205 EKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPN 264
           E  SP +  S      + +++ P +    E+EE+                  +SPE   +
Sbjct: 631 EVKSPEKAKSP----TKEEAKSPEKAKSPEKEEA------------------KSPEKAKS 668

Query: 265 PGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPD 324
           P  K E +   +A   + AE +  +    K+ + +   SP+  K     +P +E  ++P+
Sbjct: 669 P-VKAEAKSPEKAKSPVKAEAK--SPEKAKSPVKEEAKSPEKAK-----SPVKEEAKSPE 720

Query: 325 SDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSES 373
               ++ V +   T ++  + VKEEA +   KA + E  +   + S E+
Sbjct: 721 K--AKSPVKEEAKTPEKAKSPVKEEAKS-PEKAKSPEKAKTLDVKSPEA 766



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 59/274 (21%), Positives = 110/274 (40%), Gaps = 29/274 (10%)

Query: 101 EKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRT-TDLK 159
           E+  VT  V  EEE+    E G     G+   +EG +    + P  E  SPE    + +K
Sbjct: 462 EETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVK 521

Query: 160 CDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYC----ESENKWSQEKHSPWEGVSD 215
            ++ S +E +   +E  +   +  SP  +  P  E      E+++   +E  SP E  S 
Sbjct: 522 EEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSP 581

Query: 216 HLAH----------REPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNP 265
             A            E KS +  +   +EE +S + +       ++    ++SPE   +P
Sbjct: 582 EKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSP 641

Query: 266 GGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKE---------SSTNAPT 316
             K E +   +A      ++E  +    K+ +     SP+  K              +P 
Sbjct: 642 -TKEEAKSPEKAKS--PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV 698

Query: 317 REPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEA 350
           +E  ++P+    ++ V +   + ++  + VKEEA
Sbjct: 699 KEEAKSPEK--AKSPVKEEAKSPEKAKSPVKEEA 730



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 60/286 (20%), Positives = 110/286 (38%), Gaps = 27/286 (9%)

Query: 102 KMPVTASVLSEEE-QTHCLEIGSNTRHGKSNLSEGKKSAE-LNSPLRERL-------SPE 152
           K PV     S E+ ++   E   +    KS + E  K+ E   SP++E         SPE
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754

Query: 153 N-RTTDLKC--------DSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWS 203
             +T D+K         + +     +   +    V+E+  SP  +  P+ E  ++  K  
Sbjct: 755 KAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEI 814

Query: 204 QEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEP-- 261
            +K      V +    +E K ++P +K +EE+  +   + +   S  E+    E+P+P  
Sbjct: 815 PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKV 874

Query: 262 --QPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREP 319
             +  P  +   E  +EA K   AE ++   + EK    +     D++ +  T    +EP
Sbjct: 875 EEKKEPAVEKPKESKVEA-KKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEP 933

Query: 320 ----GQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE 361
                + P     + +        KE      EE      KA  ++
Sbjct: 934 DDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDD 979



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 40/199 (20%), Positives = 76/199 (38%), Gaps = 6/199 (3%)

Query: 213 VSDHLAHREPKSQKPFRKMQEE----EEESWSTSSDLTISISEDDLILESPEPQPNPGGK 268
           VS H+  +  +  K   K ++E    EE++  T     ++  E+    E    +   G +
Sbjct: 432 VSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEE 491

Query: 269 MEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVP 328
            E E G E  K   AE+        K+ + +   SP +E +S      + P +    +  
Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSP-AEAKSPEKEEAKSPAEVKSPEKA 550

Query: 329 RAQVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIK 388
           ++   +   +  E  +  KEEA +   +  + E  +  A   ++S     S     S +K
Sbjct: 551 KSPAKEEAKSPPEAKSPEKEEAKS-PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609

Query: 389 EAKPAVWLNSVPTREQEVS 407
           E   +      P +E+  S
Sbjct: 610 EEAKSPAEAKSPVKEEAKS 628


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 58/278 (20%), Positives = 113/278 (40%), Gaps = 23/278 (8%)

Query: 197 ESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLIL 256
           E+E +    K SP +  +  +   E + ++   + +EEEE+  + S       SE +   
Sbjct: 500 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSS 559

Query: 257 ESPEPQPNPG---GKMEGEDGIEALKLIHAEQERVALSTEKNCILQT-LSSPDSEKESST 312
           E  E +   G    + EGE+  EA +    E++   ++T++  +    +  P+  K    
Sbjct: 560 EKEEGEQEEGETEAEAEGEEA-EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP 618

Query: 313 NAPTREPGQTPDSDVPRAQVGQH---VATLKEHDNS------VKEEATALLRKALTEECG 363
            +P  E G++P    P  + G+     + ++E   S      V+E+  + + K+  EE  
Sbjct: 619 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 678

Query: 364 R----RSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKS----- 414
           +    +S +  ++S   +          KE K A     V  +E++       K      
Sbjct: 679 KSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPV 738

Query: 415 KKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQK 452
           K+E VA  + IT++    L K+   +    Q E   +K
Sbjct: 739 KEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEK 776


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 58/278 (20%), Positives = 113/278 (40%), Gaps = 23/278 (8%)

Query: 197 ESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLIL 256
           E+E +    K SP +  +  +   E + ++   + +EEEE+  + S       SE +   
Sbjct: 124 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSS 183

Query: 257 ESPEPQPNPG---GKMEGEDGIEALKLIHAEQERVALSTEKNCILQT-LSSPDSEKESST 312
           E  E +   G    + EGE+  EA +    E++   ++T++  +    +  P+  K    
Sbjct: 184 EKEEGEQEEGETEAEAEGEEA-EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP 242

Query: 313 NAPTREPGQTPDSDVPRAQVGQH---VATLKEHDNS------VKEEATALLRKALTEECG 363
            +P  E G++P    P  + G+     + ++E   S      V+E+  + + K+  EE  
Sbjct: 243 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 302

Query: 364 R----RSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKS----- 414
           +    +S +  ++S   +          KE K A     V  +E++       K      
Sbjct: 303 KSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPV 362

Query: 415 KKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQK 452
           K+E VA  + IT++    L K+   +    Q E   +K
Sbjct: 363 KEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEK 400


>gi|54633319 PDZ domain-containing guanine nucleotide exchange factor
            I [Homo sapiens]
          Length = 1601

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 75/342 (21%), Positives = 132/342 (38%), Gaps = 49/342 (14%)

Query: 41   STEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQ-- 98
            S+ H SP  +   S    ++   +A+S N++DS   + S+ +  ++        A+LQ  
Sbjct: 1232 SSLHSSPPASPQGSPHKGYTLIPSAKSDNLSDSSHSEISSRSSIVSNCSVDSMSAALQDE 1291

Query: 99   --IGEKMPVTASVLSEEEQTHCLEIGSNTRHGKS----NLSEGKKSAELNSPLRERLSPE 152
                + + V  S  + E+  H   IG +++HG        S  K  A  +S   E +S E
Sbjct: 1292 RCSSQALAVPESTGALEKTEHASGIGDHSQHGPGWTLLKPSLIKCLAVSSSVSNEEISQE 1351

Query: 153  NRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEG 212
            +   +   DS  GS     +  H   +         P P S        W          
Sbjct: 1352 HIIIEA-ADSGRGSWTSCSSSSHDNFQSL-------PNPKS--------WDFLNSYRHTH 1395

Query: 213  VSDHLAHREPKSQKPFRKMQE-----------EEEESWSTSSDLTISISEDDLILESPEP 261
            + D +A  EP   +P+   +             E +SW++SS L+ +   +   ++    
Sbjct: 1396 LDDPIAEVEPTDSEPYSCSKSCSRTCGQCKGSLERKSWTSSSSLSDTYEPNYGTVKRRVL 1455

Query: 262  QPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQ 321
            +  P    EG D  +A   ++   + V  STEK  I+  ++SP  +         REP  
Sbjct: 1456 ESTPAESSEGLDPKDATDPVY---KTVTSSTEKGLIVYCVTSPKKDDR------YREPPP 1506

Query: 322  TPDS----DVPRAQVGQHVATLKEHDNSVKEEATALLRKALT 359
            TP       +   + G H   LK  D SV  + + ++  +L+
Sbjct: 1507 TPPGYLGISLADLKEGPH-THLKPPDYSVAVQRSKMMHNSLS 1547


>gi|20336260 retinoblastoma protein-binding zinc finger protein
           isoform b [Homo sapiens]
          Length = 1682

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 56/225 (24%), Positives = 84/225 (37%), Gaps = 34/225 (15%)

Query: 211 EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME 270
           E  S       PKS+K  +K QE + +  +   D+ +  SE D    S   + +  G  E
Sbjct: 155 ERASARSKRSSPKSRKGKKKSQENKNKG-NKIQDIQLKTSEPDFT--SANMRDSAEGPKE 211

Query: 271 GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA 330
            E+   A  L            E+   LQ ++S +   E +T AP  EP   PD  +  A
Sbjct: 212 DEEKPSASAL------------EQPATLQEVASQEVPPELATPAPAWEPQPEPDERLEAA 259

Query: 331 -----QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNS 385
                 +G+     +E D   +E+          E+ G   A   +E+S   P I  D  
Sbjct: 260 ACEVNDLGEEEEEEEEEDEEEEEDDD----DDELEDEGEEEASMPNENSVKEPEIRCDE- 314

Query: 386 GIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEA 430
                KP   L    T  +E    C + +     A  IP T+ EA
Sbjct: 315 -----KPEDLLEEPKTTSEETLEDCSEVTP----AMQIPRTKEEA 350


>gi|20336258 retinoblastoma protein-binding zinc finger protein
           isoform a [Homo sapiens]
          Length = 1718

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 56/225 (24%), Positives = 84/225 (37%), Gaps = 34/225 (15%)

Query: 211 EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME 270
           E  S       PKS+K  +K QE + +  +   D+ +  SE D    S   + +  G  E
Sbjct: 155 ERASARSKRSSPKSRKGKKKSQENKNKG-NKIQDIQLKTSEPDFT--SANMRDSAEGPKE 211

Query: 271 GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA 330
            E+   A  L            E+   LQ ++S +   E +T AP  EP   PD  +  A
Sbjct: 212 DEEKPSASAL------------EQPATLQEVASQEVPPELATPAPAWEPQPEPDERLEAA 259

Query: 331 -----QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNS 385
                 +G+     +E D   +E+          E+ G   A   +E+S   P I  D  
Sbjct: 260 ACEVNDLGEEEEEEEEEDEEEEEDDD----DDELEDEGEEEASMPNENSVKEPEIRCDE- 314

Query: 386 GIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEA 430
                KP   L    T  +E    C + +     A  IP T+ EA
Sbjct: 315 -----KPEDLLEEPKTTSEETLEDCSEVTP----AMQIPRTKEEA 350


>gi|148806891 hypothetical protein LOC54906 [Homo sapiens]
          Length = 2430

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 51/196 (26%), Positives = 75/196 (38%), Gaps = 21/196 (10%)

Query: 149 LSPENRTT---DLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSE----YCESE-- 199
           + PEN T    DL  +S    + + L      + +   S   S  PVSE    +C SE  
Sbjct: 509 VQPENTTAAHNDLPENSIVNYDSQALNM----LADLALSSATSSTPVSEARNLHCSSELP 564

Query: 200 -NKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILES 258
            N     K +   G SDH  HR  K+QK         +   ++ SDLT+S  E+ L+  S
Sbjct: 565 QNDVLLSKENSLRGTSDHEYHRGVKTQKGELLPNPSSDRKSNSGSDLTVSQDEESLVPCS 624

Query: 259 PEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAP--T 316
             P        E     E L+   A Q           +L T  S    +E    +P   
Sbjct: 625 QAPAKAQSALTE-----EMLESSDASQSSSVSVEHSYALLLTEHSKKHLQEREILSPLFP 679

Query: 317 REPGQTPDSDVPRAQV 332
           R   ++P++  P  +V
Sbjct: 680 RNGTKSPEAATPVGKV 695


>gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens]
          Length = 880

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 55/270 (20%), Positives = 102/270 (37%), Gaps = 38/270 (14%)

Query: 302 SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRK----- 356
           SS  S +  ST++PT  P  TP    P ++  Q V     H +   +  ++++ K     
Sbjct: 414 SSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSM 473

Query: 357 ALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLN------SVPTREQEVSSGC 410
           +L E+    +   S +     P +    S        + LN      S+ +  + + S C
Sbjct: 474 SLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHC 533

Query: 411 GDKSKKENVAADIPITETEAYQLLK--KATLQDNT---------NQTENRFQKT------ 453
             + ++E+      +   E     K  + + +D T         N  EN    T      
Sbjct: 534 KSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFT 593

Query: 454 ----DASVSHLSGLNI--GSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKS 507
               D++    + LN+    G  E   +++ A E   S    +  + +EN   P    ++
Sbjct: 594 AKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQT 653

Query: 508 NALWDESDDSNSEIEAALRPRNHNTDDSDD 537
            A    + +  S  ++AL+    +TDDSDD
Sbjct: 654 EATGPSAHEETSTRDSALQ----DTDDSDD 679


>gi|34996489 pleckstrin homology domain interacting protein [Homo
            sapiens]
          Length = 1821

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 68/291 (23%), Positives = 124/291 (42%), Gaps = 48/291 (16%)

Query: 43   EHKSPQPTKNFSIPDPHSH---------RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDG 93
            E+K P  +KN +    H H         +QT Q +  T S + +T   ++ +      +G
Sbjct: 765  ENKIPTVSKNHA----HEHFLDLGESKKQQTNQHNYRTRSALEETPRPSEEIE-----NG 815

Query: 94   KASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPEN 153
             +S   GE + V+    SEEE+      GS++ +  S+ S+    A +N    +++ P+N
Sbjct: 816  SSSSDEGEVVAVSGGT-SEEEERAWHSDGSSSDYS-SDYSDWTADAGINLQPPKKV-PKN 872

Query: 154  RTTDLKCDSSSGSEGEILTREHIEVEEKRASP----PVSP------------IPVSEYCE 197
            +T   +  S    E E   ++ I+ E+K+ +     P+SP            + V E   
Sbjct: 873  KTKKAESSSDEEEESEKQKQKQIKKEKKKVNEEKDGPISPKKKKPKERKQKRLAVGEL-- 930

Query: 198  SENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILE 257
            +EN  + E+  P   ++D +  R      PF     +E   +    +  + ++  + I  
Sbjct: 931  TENGLTLEEWLPSTWITDTIPRR-----CPFVPQMGDEVYYFRQGHEAYVEMARKNKIY- 984

Query: 258  SPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEK 308
            S  P+  P  KME  +  E +K++  + E V L T   C+      PD+ K
Sbjct: 985  SINPKKQPWHKMELREQ-ELMKIVGIKYE-VGLPT-LCCLKLAFLDPDTGK 1032


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 103/519 (19%), Positives = 192/519 (36%), Gaps = 59/519 (11%)

Query: 37   MRDFSTEHKSPQPTKNF-SIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGK- 94
            M D +   ++  P++ F +I    S   + + S   D   V   N     +K+D  DGK 
Sbjct: 1143 MSDETNNEETESPSQEFVNITKYESSLYSQEYSKPAD---VTPLNGFSEGSKTDATDGKD 1199

Query: 95   -----ASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERL 149
                 +++     M       S     +C E+ ++T     +      S +++      L
Sbjct: 1200 YNASASTISPPSSMEEDKFSRSALRDAYCSEVKASTTLDIKDSISAVSSEKVSPSKSPSL 1259

Query: 150  SPENRTTDLKCDSSSGSEGEILTREHIEV----EEKRASPPVSPIPVSEYCESENKWSQE 205
            SP   +   K      S    LT   I+V    E    SP V+   V E+C S    + E
Sbjct: 1260 SPSPPSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAPVSPEVTQEVVEEHCASPEDKTLE 1319

Query: 206  KHSPWEGVSDHLAH----REPKSQKPFRKMQE--EEEESWSTSSDLTISISEDDLILESP 259
              SP + V+    H    + P  +K      E  E+  +   S + + +  E++    SP
Sbjct: 1320 VVSPSQSVTGSAGHTPYYQSPTDEKSSHLPTEVIEKPPAVPVSFEFSDAKDENERASVSP 1379

Query: 260  EPQPNPGGKMEGEDGIEALK---LIHAEQERVA-LSTEKNCILQTLSSPDSEKESSTNAP 315
              +P P  +   E  +  L+   LI +E    + LS +     +   SP  EK     +P
Sbjct: 1380 MDEPVPDSESPIEKVLSPLRSPPLIGSESAYESFLSADDKASGRGAESPFEEKSGKQGSP 1439

Query: 316  TREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSC 375
             +    +P S++    + Q            K+E  +     + E+ G+       E+  
Sbjct: 1440 DQ---VSPVSEMTSTSLYQD-----------KQEGKSTDFAPIKEDFGQEKKTDDVEAMS 1485

Query: 376  SLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLK 435
            S P++  D   + +  P                   D S+  +   D  ++ +E     K
Sbjct: 1486 SQPALALDERKLGDVSPTQI----------------DVSQFGSFKEDTKMSISEGTVSDK 1529

Query: 436  KATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRH 495
             AT  D     E+ +   +  V+ +S  ++ + +F   T + ++   S  +  GSP S  
Sbjct: 1530 SATPVDE-GVAEDTYSHME-GVASVSTASVATSSFPEPTTDDVS--PSLHAEVGSPHSTE 1585

Query: 496  ENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDD 534
             +    V  +++   + E++ S S+ E   RP + +  D
Sbjct: 1586 VDDSLSVSVVQTPTTFQETEMSPSK-EECPRPMSISPPD 1623


>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
          Length = 556

 Score = 37.7 bits (86), Expect = 0.027
 Identities = 87/416 (20%), Positives = 152/416 (36%), Gaps = 63/416 (15%)

Query: 93  GKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPE 152
           G++ L+  EK  +   V  EEE        + +R  K +L+  KK     +P  +   PE
Sbjct: 38  GRSHLEPEEKQALKRLV--EEELLKMQVDEAASREDKLDLT--KKGKRPPTPCSD---PE 90

Query: 153 NRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEG 212
            +      +S SGSE                 PP      +E   ++ +  +      E 
Sbjct: 91  RKRFRFNSESESGSEAS---------SPDYFGPPAKNGVAAEVSPAKEENPRRASKAVEE 141

Query: 213 VSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTI---------SISEDDLILESPEPQP 263
            SD    R+  +Q+     +EEE+     +    +         S+S      ES E + 
Sbjct: 142 SSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVSRKQAREESEESEA 201

Query: 264 NP----GGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREP 319
            P      K+EG  G ++LK    E E   L+ +K            ++E       +E 
Sbjct: 202 EPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKK-----------EQREEEVEEEEKEE 250

Query: 320 GQTPDSDVPRAQV-GQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSL- 377
            +      PR +  G+  +  +E     K +A  LL  + +EE  + +A    +S     
Sbjct: 251 DEEKGDWKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDRE 310

Query: 378 PSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKA 437
           P +   +    + K    L+   + E E  SG G+ + K +                +K 
Sbjct: 311 PPVQRKSEDRTQLKGGKRLSG--SSEDEEDSGKGEPTAKGS----------------RKM 352

Query: 438 TLQDNTNQTENRFQKTDASVSHLSGLNIG--SGAFETKTANKIASEASFSSSEGSP 491
               +T+  E+  ++ + S S   G   G        K++ K  + +S SSS+GSP
Sbjct: 353 ARLGSTSGEESDLER-EVSDSEAGGGPQGERKNRSSKKSSRKGRTRSSSSSSDGSP 407


>gi|190194423 SPARC-like 1 [Homo sapiens]
          Length = 664

 Score = 37.4 bits (85), Expect = 0.035
 Identities = 62/319 (19%), Positives = 121/319 (37%), Gaps = 39/319 (12%)

Query: 232 QEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALS 291
           +E E+E+  ++ D +   +E   +L+S E       + +G+   + L L   E     LS
Sbjct: 50  EENEKETAVSTEDDSHHKAEKSSVLKSKEESHEQSAE-QGKSSSQELGLKDQEDSDGHLS 108

Query: 292 -------TEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDN 344
                  TE    ++   S   EK+ S N     PG +  +D   +   + +   +E+  
Sbjct: 109 VNLEYAPTEGTLDIKEDMSEPQEKKLSENTDFLAPGVSSFTD---SNQQESITKREENQE 165

Query: 345 SVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILN-DNSGIKEAKPAVWLNSVPTRE 403
             +  +   L ++     G R   +  +     P+I N +    KE       N    R+
Sbjct: 166 QPRNYSHHQLNRSSKHSQGLRDQGNQEQD----PNISNGEEEEEKEPGEVGTHNDNQERK 221

Query: 404 QEVS-SGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSG 462
            E+       K +++N  +D  + E++    + K    +     + +   ++A +   + 
Sbjct: 222 TELPREHANSKQEEDNTQSDDILEESDQPTQVSKMQEDEFDQGNQEQEDNSNAEMEEENA 281

Query: 463 LNIGSGAFETKTANKIASEASFSSSEGSP----LSRHENKKKPVINLKSNALWDESDDSN 518
            N+          NK   E  + S EG      +S H+  ++  ++     L + +DD N
Sbjct: 282 SNV----------NKHIQETEWQSQEGKTGLEAISNHKETEEKTVS--EALLMEPTDDGN 329

Query: 519 SEIEAALRPRNHNTDDSDD 537
           +       PRNH  DD  D
Sbjct: 330 TT------PRNHGVDDDGD 342


>gi|190341024 SPARC-like 1 [Homo sapiens]
          Length = 664

 Score = 37.4 bits (85), Expect = 0.035
 Identities = 62/319 (19%), Positives = 121/319 (37%), Gaps = 39/319 (12%)

Query: 232 QEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALS 291
           +E E+E+  ++ D +   +E   +L+S E       + +G+   + L L   E     LS
Sbjct: 50  EENEKETAVSTEDDSHHKAEKSSVLKSKEESHEQSAE-QGKSSSQELGLKDQEDSDGHLS 108

Query: 292 -------TEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDN 344
                  TE    ++   S   EK+ S N     PG +  +D   +   + +   +E+  
Sbjct: 109 VNLEYAPTEGTLDIKEDMSEPQEKKLSENTDFLAPGVSSFTD---SNQQESITKREENQE 165

Query: 345 SVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILN-DNSGIKEAKPAVWLNSVPTRE 403
             +  +   L ++     G R   +  +     P+I N +    KE       N    R+
Sbjct: 166 QPRNYSHHQLNRSSKHSQGLRDQGNQEQD----PNISNGEEEEEKEPGEVGTHNDNQERK 221

Query: 404 QEVS-SGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSG 462
            E+       K +++N  +D  + E++    + K    +     + +   ++A +   + 
Sbjct: 222 TELPREHANSKQEEDNTQSDDILEESDQPTQVSKMQEDEFDQGNQEQEDNSNAEMEEENA 281

Query: 463 LNIGSGAFETKTANKIASEASFSSSEGSP----LSRHENKKKPVINLKSNALWDESDDSN 518
            N+          NK   E  + S EG      +S H+  ++  ++     L + +DD N
Sbjct: 282 SNV----------NKHIQETEWQSQEGKTGLEAISNHKETEEKTVS--EALLMEPTDDGN 329

Query: 519 SEIEAALRPRNHNTDDSDD 537
           +       PRNH  DD  D
Sbjct: 330 TT------PRNHGVDDDGD 342


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 37.0 bits (84), Expect = 0.046
 Identities = 52/239 (21%), Positives = 91/239 (38%), Gaps = 15/239 (6%)

Query: 129  KSNLSEGKKSAELNSPLRERLSPENRTTDLKCD--SSSGSEGEILTREHIEVEEKRASPP 186
            K +LSE ++S E      E    E+   D   D   S   + +    E  E +E  +   
Sbjct: 1038 KESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEE 1097

Query: 187  VSPIPVSEYCESENKWSQEKHSPWEGVSDHL-AHREPKSQKPFRKMQEEEEESWSTSSDL 245
             +   V+   E+ +     + S +E  S+   +  E + +   R+ +EEEEE    + + 
Sbjct: 1098 ETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEES 1157

Query: 246  TISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPD 305
              S   +D   +  E    PG       G+E  + +  E E VA     + + +      
Sbjct: 1158 MASAGPEDFEQDGEEAALAPGAPAVDSLGME--EEVDIETEAVAPEERPSMLDEPPLPVG 1215

Query: 306  SEKESSTNAPTREPGQTPD-----SDVPRAQVGQHVATLK-----EHDNSVKEEATALL 354
             E+ + +  P  EPG + +     S  P A+  +    L      EHD  V+ E   +L
Sbjct: 1216 VEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMML 1274


>gi|17978469 cyclin T2 isoform b [Homo sapiens]
          Length = 730

 Score = 36.2 bits (82), Expect = 0.078
 Identities = 49/213 (23%), Positives = 78/213 (36%), Gaps = 22/213 (10%)

Query: 63  QTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEIG 122
           Q A SS+VT    ++          +D  +   SL++   +P T    S+EE    +++ 
Sbjct: 471 QAASSSSVTSPIKMKIPIANTEKYMADKKEKSGSLKLRIPIPPTDKSASKEELKMKIKVS 530

Query: 123 SNTRHGKSNLSEGKK-------SAELNSPLRERLSPENRTTDLK---CDSSSGSEGEILT 172
           S+ RH  S+   GK        S +     +E  S  + T+  K     S S S G   +
Sbjct: 531 SSERHSSSDEGSGKSKHSSPHISRDHKEKHKEHPSSRHHTSSHKHSHSHSGSSSGGSKHS 590

Query: 173 REHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQ 232
            + I     R     SP+ +S    S +  S  K         H+            K  
Sbjct: 591 ADGIPPTVLR-----SPVGLSSDGISSSSSSSRKRL-------HVNDASHNHHSKMSKSS 638

Query: 233 EEEEESWSTSSDLTISISEDDLILESPEPQPNP 265
           +    S S+SS +   IS  + +   P P P P
Sbjct: 639 KSSGSSSSSSSSVKQYISSHNSVFNHPLPPPPP 671


>gi|154090979 hypothetical protein LOC57481 [Homo sapiens]
          Length = 1709

 Score = 36.2 bits (82), Expect = 0.078
 Identities = 60/264 (22%), Positives = 97/264 (36%), Gaps = 34/264 (12%)

Query: 185 PPVSPIPVSEYCESENKWSQEKHSPWEGV-SDHLAH-REPKSQKPFRKMQEEEEESWSTS 242
           PP S    S   ++E   S  ++ P EG  S+ LAH    +S   F   QE   ES S  
Sbjct: 763 PPRSLFQSSRKPDAEEVSSDSENIPEEGDGSEELAHGHSSQSLGKFEDEQEVFSESKSFV 822

Query: 243 SDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLS 302
            DL+ S  E DL   S                 +AL+    E E   + TE +  ++  +
Sbjct: 823 EDLSSSEEELDLRCLS-----------------QALE----EPEDAEVFTESSSYVEKYN 861

Query: 303 SPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEEC 362
           + D    S  + P R P Q       + +V        E  N   ++    L      + 
Sbjct: 862 TSDDCSSSEEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDFMQQ----LPSRCPSQP 917

Query: 363 GRRSAIHSSESSCSLPSILNDNSGIKEAKP----AVWLNSVPTREQEVSSGCGDKSKKEN 418
                +     + S+ + +  +  ++   P      W+N  P  EQEVSS     + +E+
Sbjct: 918 IMNPTVQQQVPTSSVGTSIKQSDSVEPIPPRHPFQPWVN--PKVEQEVSSSPKSMAVEES 975

Query: 419 VAADIPITETEAYQLLKKATLQDN 442
           ++   P+      Q L    +Q N
Sbjct: 976 ISMK-PLPPKLLCQPLMNPKVQQN 998


>gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens]
          Length = 860

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 55/259 (21%), Positives = 98/259 (37%), Gaps = 36/259 (13%)

Query: 302 SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE 361
           SS  S +  ST++PT  P  TP    P ++  Q V     H +   +       + L+ +
Sbjct: 414 SSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDNN----NEKLSPK 469

Query: 362 CGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAA 421
            G    + S   S    +     S IK      W +S+ +  + + S C  + ++E+   
Sbjct: 470 PGTGEPVLSLHYSTEGTT----TSTIKLNFTDEW-SSIASSSRGIGSHCKSEGQEESFVP 524

Query: 422 DIPITETEAYQLLK--KATLQDNT---------NQTENRFQKT----------DASVSHL 460
              +   E     K  + + +D T         N  EN    T          D++    
Sbjct: 525 QSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFTAKPLDSNSGER 584

Query: 461 SGLNI--GSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSN 518
           + LN+    G  E   +++ A E   S    +  + +EN   P    ++ A    + +  
Sbjct: 585 NDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQTEATGPSAHEET 644

Query: 519 SEIEAALRPRNHNTDDSDD 537
           S  ++AL+    +TDDSDD
Sbjct: 645 STRDSALQ----DTDDSDD 659


>gi|4502805 chromogranin A precursor [Homo sapiens]
          Length = 457

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 38/154 (24%), Positives = 66/154 (42%), Gaps = 15/154 (9%)

Query: 129 KSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVS 188
           + +  E +KS E     R +  PE    + K + ++ + GE    E  E EE   + P +
Sbjct: 133 REDSKEAEKSGEATDGARPQALPEPMQ-ESKAEGNNQAPGE----EEEEEEEATNTHPPA 187

Query: 189 PIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPK-SQKP---FRKMQEEEEESWSTSSD 244
            +P  +Y   + +   E      G+S  L  RE   S +P    ++ +EEEEE  + + +
Sbjct: 188 SLPSQKYPGPQAEGDSE------GLSQGLVDREKGLSAEPGWQAKREEEEEEEEEAEAGE 241

Query: 245 LTISISEDDLILESPEPQPNPGGKMEGEDGIEAL 278
             +   E   ++ +P P        +GE   EAL
Sbjct: 242 EAVPEEEGPTVVLNPHPSLGYKEIRKGESRSEAL 275


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 10/126 (7%)

Query: 270 EGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPR 329
           E +DG+     +   + R ++ST ++   +  +SPD  + S  N   R  G+   S    
Sbjct: 7   EEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDG-RTSPINEDIRSSGRNSPSAAST 65

Query: 330 AQVGQHVATLKEHDNSVKEEATALLRK---------ALTEECGRRSAIHSSESSCSLPSI 380
           +       T+K+    VKEEA++ L+          + TEE  R S+  +     S P+ 
Sbjct: 66  SSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS 125

Query: 381 LNDNSG 386
            ++  G
Sbjct: 126 PSEGEG 131


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 10/126 (7%)

Query: 270 EGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPR 329
           E +DG+     +   + R ++ST ++   +  +SPD  + S  N   R  G+   S    
Sbjct: 561 EEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDG-RTSPINEDIRSSGRNSPSAAST 619

Query: 330 AQVGQHVATLKEHDNSVKEEATALLRK---------ALTEECGRRSAIHSSESSCSLPSI 380
           +       T+K+    VKEEA++ L+          + TEE  R S+  +     S P+ 
Sbjct: 620 SSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS 679

Query: 381 LNDNSG 386
            ++  G
Sbjct: 680 PSEGEG 685


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 10/126 (7%)

Query: 270 EGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPR 329
           E +DG+     +   + R ++ST ++   +  +SPD  + S  N   R  G+   S    
Sbjct: 561 EEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDG-RTSPINEDIRSSGRNSPSAAST 619

Query: 330 AQVGQHVATLKEHDNSVKEEATALLRK---------ALTEECGRRSAIHSSESSCSLPSI 380
           +       T+K+    VKEEA++ L+          + TEE  R S+  +     S P+ 
Sbjct: 620 SSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS 679

Query: 381 LNDNSG 386
            ++  G
Sbjct: 680 PSEGEG 685


>gi|55953110 retinoblastoma protein-binding zinc finger protein
           isoform c [Homo sapiens]
          Length = 1481

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 39/152 (25%), Positives = 60/152 (39%), Gaps = 19/152 (12%)

Query: 284 EQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA-----QVGQHVAT 338
           E++  A + E+   LQ ++S +   E +T AP  EP   PD  +  A      +G+    
Sbjct: 12  EEKPSASALEQPATLQEVASQEVPPELATPAPAWEPQPEPDERLEAAACEVNDLGEEEEE 71

Query: 339 LKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNS 398
            +E D   +E+          E+ G   A   +E+S   P I  D       KP   L  
Sbjct: 72  EEEEDEEEEEDDD----DDELEDEGEEEASMPNENSVKEPEIRCDE------KPEDLLEE 121

Query: 399 VPTREQEVSSGCGDKSKKENVAADIPITETEA 430
             T  +E    C + +     A  IP T+ EA
Sbjct: 122 PKTTSEETLEDCSEVTP----AMQIPRTKEEA 149


>gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens]
          Length = 778

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 55/260 (21%), Positives = 101/260 (38%), Gaps = 14/260 (5%)

Query: 59  HSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHC 118
           H  R++   S ++DS + + S+      KS +   +  L  G + P          + + 
Sbjct: 202 HGARRSKPFSELSDSDLEEKSSSLSPYVKSSSSHNEVFLP-GSRGPRRRKSKQHFVEKNK 260

Query: 119 LEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEV 178
           L +G  T    S L    K    + P  E++S   R TD K    +  E E    +  + 
Sbjct: 261 LTLGLPTPKTDSYLQLHNKKRGESHP--EQISYPVRVTD-KTSIQNAKEMENAAIDPEDK 317

Query: 179 EEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEES 238
             +RA    +        ES    +  +  P + V+DH   R P   K  ++ + +    
Sbjct: 318 WHQRAQQLKNYQEHWSQYESTKSSNVPRGQPSDMVNDHQPSRRPAKLKIRKQCKHQNGLK 377

Query: 239 WSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCIL 298
            ST+ ++T S    +     P  Q N    ++     E++ ++HA    V  S       
Sbjct: 378 SSTTEEVTASQGNQN---NPPRQQQNQNKPLDTSTKPESIVIMHASNNDVQAS------- 427

Query: 299 QTLSSPDSEKESSTNAPTRE 318
           + L S + ++ S+T AP ++
Sbjct: 428 RALRSHNLKETSNTFAPPKQ 447


>gi|38176300 nestin [Homo sapiens]
          Length = 1621

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 48/191 (25%), Positives = 72/191 (37%), Gaps = 18/191 (9%)

Query: 141  LNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESEN 200
            +  PL E      R   L+       E   L  E  E+  K   P   P    E  E+E 
Sbjct: 1120 MEPPLEEESLEAKRVQGLEGPRKDLEEAGGLGTEFSELPGKSRDPWEPPREGREESEAEA 1179

Query: 201  KWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPE 260
                E+  P    ++ L H    +  P+    EE EE       ++ S +   ++ ++P 
Sbjct: 1180 PRGAEEAFP----AETLGHTGSDAPSPWPLGSEEAEEDVPPVL-VSPSPTYTPILEDAPG 1234

Query: 261  PQPNPGGKMEGEDGI----EALKLIHAEQERVALSTEKNCILQTLSSPDSE-KESSTNAP 315
            PQP   G  E   G+    EAL  + +EQE +          +    P  E +ES   + 
Sbjct: 1235 PQPQAEGSQEASWGVQGRAEALGKVESEQEELGSG-------EIPEGPQEEGEESREESE 1287

Query: 316  TREPGQT-PDS 325
              E G+T PDS
Sbjct: 1288 EDELGETLPDS 1298



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 32/159 (20%), Positives = 63/159 (39%), Gaps = 9/159 (5%)

Query: 197 ESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESW-----STSSDLTISISE 251
           E EN+  +   SP  G  + L     ++Q+P R +++E +E++          L     E
Sbjct: 671 EKENQ--EPLRSPEVGDEEALRPLTKENQEPLRSLEDENKEAFRSLEKENQEPLKTLEEE 728

Query: 252 DDLILESPEPQPNPGGKMEGEDGIEALKLIHAE--QERVALSTEKNCILQTLSSPDSEKE 309
           D  I+   E + +   +   E   E L+ +  E  Q R +L  +    L+     D E  
Sbjct: 729 DQSIVRPLETENHKSLRSLEEQDQETLRTLEKETQQRRRSLGEQDQMTLRPPEKVDLEPL 788

Query: 310 SSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKE 348
            S +     P +  + +  ++   + V  +K  +  + E
Sbjct: 789 KSLDQEIARPLENENQEFLKSLKEESVEAVKSLETEILE 827


>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 948

 Score = 34.7 bits (78), Expect = 0.23
 Identities = 64/309 (20%), Positives = 121/309 (39%), Gaps = 43/309 (13%)

Query: 89  DNIDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRER 148
           +N DG+ S  +  +    +   S+E+ +             SN++ GKK  E++  +  +
Sbjct: 492 ENKDGEKSRTVSSRKKPASKATSDEKDSF------------SNITRGKKDGEISRKVSSQ 539

Query: 149 LSPENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHS 208
             P  + T  + DS  G     + RE+ + E+ R      P  +    + ++        
Sbjct: 540 KPPTLKGTSDEEDSVLG-----IARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARG 594

Query: 209 PWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILE-SPEPQPNPGG 267
              G       R    +KP  +   +E++S+   S++T    + ++  + S +  P   G
Sbjct: 595 KKYG---EKTKRVSSRKKPSLEATSDEKDSF---SNITREKKDGEISRKVSSQKPPALKG 648

Query: 268 KMEGEDGIEALKLIHAEQERV-ALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSD 326
             + ED +  +   + + E+   +S+EK      L +   EK+S  N    +     D +
Sbjct: 649 TSDEEDSVLGIARENKDGEKSRTVSSEKP---PGLKATSDEKDSVLNIARGK----KDGE 701

Query: 327 VPRAQVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSE-------SSCSLPS 379
             R    Q   TLK    +  +E  ++L  A   + G +S   SSE       +S    S
Sbjct: 702 KTRTVSSQKPPTLK----ATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDS 757

Query: 380 ILNDNSGIK 388
           +LN   G K
Sbjct: 758 VLNIARGKK 766


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.304    0.121    0.336 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,475,994
Number of Sequences: 37866
Number of extensions: 1109647
Number of successful extensions: 3397
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 225
Number of HSP's that attempted gapping in prelim test: 3184
Number of HSP's gapped (non-prelim): 396
length of query: 540
length of database: 18,247,518
effective HSP length: 107
effective length of query: 433
effective length of database: 14,195,856
effective search space: 6146805648
effective search space used: 6146805648
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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