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Search of human proteins with 24431985
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24431985 piwi-like 2 [Homo sapiens]
(973 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209180418 piwi-like 2 [Homo sapiens] 1988 0.0
gi|24431985 piwi-like 2 [Homo sapiens] 1988 0.0
gi|66346725 piwi-like 1 [Homo sapiens] 676 0.0
gi|169217928 PREDICTED: similar to piwi like homolog 2 [Homo sap... 594 e-169
gi|221316711 piwi-like 4 [Homo sapiens] 566 e-161
gi|153792298 piwi-like 3 [Homo sapiens] 514 e-145
gi|6912352 eukaryotic translation initiation factor 2C, 1 [Homo ... 157 3e-38
gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo... 148 2e-35
gi|29294647 eukaryotic translation initiation factor 2C, 3 isofo... 147 5e-35
gi|29029593 eukaryotic translation initiation factor 2C, 4 [Homo... 143 9e-34
gi|29337286 eukaryotic translation initiation factor 2C, 3 isofo... 142 2e-33
gi|24308326 BR serine/threonine kinase 1 [Homo sapiens] 37 0.090
gi|55770876 notch4 preproprotein [Homo sapiens] 35 0.45
gi|14251215 Kruppel-like factor 5 [Homo sapiens] 33 0.99
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] 33 0.99
gi|19913396 smoothelin isoform b [Homo sapiens] 33 1.3
gi|30089966 CDC42 effector protein 5 [Homo sapiens] 33 1.3
gi|19913394 smoothelin isoform c [Homo sapiens] 33 1.3
gi|19913398 smoothelin isoform a [Homo sapiens] 33 1.3
gi|209954778 neurotrophic factor artemin isoform 3 precursor [Ho... 33 1.7
gi|209977029 neurotrophic factor artemin isoform 3 precursor [Ho... 33 1.7
gi|239753758 PREDICTED: hypothetical protein LOC401106 [Homo sap... 32 2.2
gi|169166137 PREDICTED: hypothetical protein LOC401106 [Homo sap... 32 2.2
gi|169165128 PREDICTED: hypothetical protein LOC401106 [Homo sap... 32 2.2
gi|29294649 dicer1 [Homo sapiens] 32 2.9
gi|29294651 dicer1 [Homo sapiens] 32 2.9
gi|217035095 tripartite motif-containing 62 [Homo sapiens] 32 2.9
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho... 32 2.9
gi|18079216 CASK interacting protein 1 [Homo sapiens] 32 3.8
gi|21389315 solute carrier family 25 (mitochondrial carrier; cit... 32 3.8
>gi|209180418 piwi-like 2 [Homo sapiens]
Length = 973
Score = 1988 bits (5150), Expect = 0.0
Identities = 973/973 (100%), Positives = 973/973 (100%)
Query: 1 MDPFRPSFRGQSPIHPSQCQAVRMPGCWPQASKPLDPALGRGAPAGRGHVFGKPEEPSTQ 60
MDPFRPSFRGQSPIHPSQCQAVRMPGCWPQASKPLDPALGRGAPAGRGHVFGKPEEPSTQ
Sbjct: 1 MDPFRPSFRGQSPIHPSQCQAVRMPGCWPQASKPLDPALGRGAPAGRGHVFGKPEEPSTQ 60
Query: 61 RGPAQRESVGLVSMFRGLGIETVSKTPLKREMLPSGRGILGRGLSANLVRKDREELSPTF 120
RGPAQRESVGLVSMFRGLGIETVSKTPLKREMLPSGRGILGRGLSANLVRKDREELSPTF
Sbjct: 61 RGPAQRESVGLVSMFRGLGIETVSKTPLKREMLPSGRGILGRGLSANLVRKDREELSPTF 120
Query: 121 WDPKVLAAGDSKMAETSVGWSRTLGRGSSDASLLPLGRAAGGISREVDKPPCTFSTPSRG 180
WDPKVLAAGDSKMAETSVGWSRTLGRGSSDASLLPLGRAAGGISREVDKPPCTFSTPSRG
Sbjct: 121 WDPKVLAAGDSKMAETSVGWSRTLGRGSSDASLLPLGRAAGGISREVDKPPCTFSTPSRG 180
Query: 181 PPQLSSPPALPQSPLHSPDRPLVLTVEHKEKELIVKQGSKGTPQSLGLNLVKIQCHNEAV 240
PPQLSSPPALPQSPLHSPDRPLVLTVEHKEKELIVKQGSKGTPQSLGLNLVKIQCHNEAV
Sbjct: 181 PPQLSSPPALPQSPLHSPDRPLVLTVEHKEKELIVKQGSKGTPQSLGLNLVKIQCHNEAV 240
Query: 241 YQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAFDGSILYLPVKLQQVLELKSQRKTDSA 300
YQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAFDGSILYLPVKLQQVLELKSQRKTDSA
Sbjct: 241 YQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAFDGSILYLPVKLQQVLELKSQRKTDSA 300
Query: 301 EISIKIQMTKILEPCSDLCIPFYNVVFRRVMKLLDMKLVGRNFYDPTSAMVLQQHRLQIW 360
EISIKIQMTKILEPCSDLCIPFYNVVFRRVMKLLDMKLVGRNFYDPTSAMVLQQHRLQIW
Sbjct: 301 EISIKIQMTKILEPCSDLCIPFYNVVFRRVMKLLDMKLVGRNFYDPTSAMVLQQHRLQIW 360
Query: 361 PGYAASIRRTDGGLFLLADVSHKVIRNDCVLDVMHAIYQQNKEHFQDECTKLLVGNIVIT 420
PGYAASIRRTDGGLFLLADVSHKVIRNDCVLDVMHAIYQQNKEHFQDECTKLLVGNIVIT
Sbjct: 361 PGYAASIRRTDGGLFLLADVSHKVIRNDCVLDVMHAIYQQNKEHFQDECTKLLVGNIVIT 420
Query: 421 RYNNRTYRIDDVDWNKTPKDSFTMSDGKEITFLEYYSKNYGITVKEEDQPLLIHRPSERQ 480
RYNNRTYRIDDVDWNKTPKDSFTMSDGKEITFLEYYSKNYGITVKEEDQPLLIHRPSERQ
Sbjct: 421 RYNNRTYRIDDVDWNKTPKDSFTMSDGKEITFLEYYSKNYGITVKEEDQPLLIHRPSERQ 480
Query: 481 DNHGMLLKGEILLLPELSFMTGIPEKMKKDFRAMKDLAQQINLSPKQHHSALECLLQRIA 540
DNHGMLLKGEILLLPELSFMTGIPEKMKKDFRAMKDLAQQINLSPKQHHSALECLLQRIA
Sbjct: 481 DNHGMLLKGEILLLPELSFMTGIPEKMKKDFRAMKDLAQQINLSPKQHHSALECLLQRIA 540
Query: 541 KNEAATNELMRWGLRLQKDVHKIEGRVLPMERINLKNTSFITSQELNWVKEVTRDPSILT 600
KNEAATNELMRWGLRLQKDVHKIEGRVLPMERINLKNTSFITSQELNWVKEVTRDPSILT
Sbjct: 541 KNEAATNELMRWGLRLQKDVHKIEGRVLPMERINLKNTSFITSQELNWVKEVTRDPSILT 600
Query: 601 IPMHFWALFYPKRAMDQARELVNMLEKIAGPIGMRMSPPAWVELKDDRIETYVRTIQSTL 660
IPMHFWALFYPKRAMDQARELVNMLEKIAGPIGMRMSPPAWVELKDDRIETYVRTIQSTL
Sbjct: 601 IPMHFWALFYPKRAMDQARELVNMLEKIAGPIGMRMSPPAWVELKDDRIETYVRTIQSTL 660
Query: 661 GAEGKIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQ 720
GAEGKIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQ
Sbjct: 661 GAEGKIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQ 720
Query: 721 INCKLGGELWGVDIPLKQLMVIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMP 780
INCKLGGELWGVDIPLKQLMVIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMP
Sbjct: 721 INCKLGGELWGVDIPLKQLMVIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMP 780
Query: 781 HQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAF 840
HQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAF
Sbjct: 781 HQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAF 840
Query: 841 ENYQPKMVVFVVQKKISTNLYLAAPQNFVTPTPGTVVDHTITSCEWVDFYLLAHHVRQGC 900
ENYQPKMVVFVVQKKISTNLYLAAPQNFVTPTPGTVVDHTITSCEWVDFYLLAHHVRQGC
Sbjct: 841 ENYQPKMVVFVVQKKISTNLYLAAPQNFVTPTPGTVVDHTITSCEWVDFYLLAHHVRQGC 900
Query: 901 GIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGHILHH 960
GIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGHILHH
Sbjct: 901 GIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGHILHH 960
Query: 961 EPAIQLCENLFFL 973
EPAIQLCENLFFL
Sbjct: 961 EPAIQLCENLFFL 973
>gi|24431985 piwi-like 2 [Homo sapiens]
Length = 973
Score = 1988 bits (5150), Expect = 0.0
Identities = 973/973 (100%), Positives = 973/973 (100%)
Query: 1 MDPFRPSFRGQSPIHPSQCQAVRMPGCWPQASKPLDPALGRGAPAGRGHVFGKPEEPSTQ 60
MDPFRPSFRGQSPIHPSQCQAVRMPGCWPQASKPLDPALGRGAPAGRGHVFGKPEEPSTQ
Sbjct: 1 MDPFRPSFRGQSPIHPSQCQAVRMPGCWPQASKPLDPALGRGAPAGRGHVFGKPEEPSTQ 60
Query: 61 RGPAQRESVGLVSMFRGLGIETVSKTPLKREMLPSGRGILGRGLSANLVRKDREELSPTF 120
RGPAQRESVGLVSMFRGLGIETVSKTPLKREMLPSGRGILGRGLSANLVRKDREELSPTF
Sbjct: 61 RGPAQRESVGLVSMFRGLGIETVSKTPLKREMLPSGRGILGRGLSANLVRKDREELSPTF 120
Query: 121 WDPKVLAAGDSKMAETSVGWSRTLGRGSSDASLLPLGRAAGGISREVDKPPCTFSTPSRG 180
WDPKVLAAGDSKMAETSVGWSRTLGRGSSDASLLPLGRAAGGISREVDKPPCTFSTPSRG
Sbjct: 121 WDPKVLAAGDSKMAETSVGWSRTLGRGSSDASLLPLGRAAGGISREVDKPPCTFSTPSRG 180
Query: 181 PPQLSSPPALPQSPLHSPDRPLVLTVEHKEKELIVKQGSKGTPQSLGLNLVKIQCHNEAV 240
PPQLSSPPALPQSPLHSPDRPLVLTVEHKEKELIVKQGSKGTPQSLGLNLVKIQCHNEAV
Sbjct: 181 PPQLSSPPALPQSPLHSPDRPLVLTVEHKEKELIVKQGSKGTPQSLGLNLVKIQCHNEAV 240
Query: 241 YQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAFDGSILYLPVKLQQVLELKSQRKTDSA 300
YQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAFDGSILYLPVKLQQVLELKSQRKTDSA
Sbjct: 241 YQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAFDGSILYLPVKLQQVLELKSQRKTDSA 300
Query: 301 EISIKIQMTKILEPCSDLCIPFYNVVFRRVMKLLDMKLVGRNFYDPTSAMVLQQHRLQIW 360
EISIKIQMTKILEPCSDLCIPFYNVVFRRVMKLLDMKLVGRNFYDPTSAMVLQQHRLQIW
Sbjct: 301 EISIKIQMTKILEPCSDLCIPFYNVVFRRVMKLLDMKLVGRNFYDPTSAMVLQQHRLQIW 360
Query: 361 PGYAASIRRTDGGLFLLADVSHKVIRNDCVLDVMHAIYQQNKEHFQDECTKLLVGNIVIT 420
PGYAASIRRTDGGLFLLADVSHKVIRNDCVLDVMHAIYQQNKEHFQDECTKLLVGNIVIT
Sbjct: 361 PGYAASIRRTDGGLFLLADVSHKVIRNDCVLDVMHAIYQQNKEHFQDECTKLLVGNIVIT 420
Query: 421 RYNNRTYRIDDVDWNKTPKDSFTMSDGKEITFLEYYSKNYGITVKEEDQPLLIHRPSERQ 480
RYNNRTYRIDDVDWNKTPKDSFTMSDGKEITFLEYYSKNYGITVKEEDQPLLIHRPSERQ
Sbjct: 421 RYNNRTYRIDDVDWNKTPKDSFTMSDGKEITFLEYYSKNYGITVKEEDQPLLIHRPSERQ 480
Query: 481 DNHGMLLKGEILLLPELSFMTGIPEKMKKDFRAMKDLAQQINLSPKQHHSALECLLQRIA 540
DNHGMLLKGEILLLPELSFMTGIPEKMKKDFRAMKDLAQQINLSPKQHHSALECLLQRIA
Sbjct: 481 DNHGMLLKGEILLLPELSFMTGIPEKMKKDFRAMKDLAQQINLSPKQHHSALECLLQRIA 540
Query: 541 KNEAATNELMRWGLRLQKDVHKIEGRVLPMERINLKNTSFITSQELNWVKEVTRDPSILT 600
KNEAATNELMRWGLRLQKDVHKIEGRVLPMERINLKNTSFITSQELNWVKEVTRDPSILT
Sbjct: 541 KNEAATNELMRWGLRLQKDVHKIEGRVLPMERINLKNTSFITSQELNWVKEVTRDPSILT 600
Query: 601 IPMHFWALFYPKRAMDQARELVNMLEKIAGPIGMRMSPPAWVELKDDRIETYVRTIQSTL 660
IPMHFWALFYPKRAMDQARELVNMLEKIAGPIGMRMSPPAWVELKDDRIETYVRTIQSTL
Sbjct: 601 IPMHFWALFYPKRAMDQARELVNMLEKIAGPIGMRMSPPAWVELKDDRIETYVRTIQSTL 660
Query: 661 GAEGKIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQ 720
GAEGKIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQ
Sbjct: 661 GAEGKIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQ 720
Query: 721 INCKLGGELWGVDIPLKQLMVIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMP 780
INCKLGGELWGVDIPLKQLMVIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMP
Sbjct: 721 INCKLGGELWGVDIPLKQLMVIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMP 780
Query: 781 HQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAF 840
HQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAF
Sbjct: 781 HQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAF 840
Query: 841 ENYQPKMVVFVVQKKISTNLYLAAPQNFVTPTPGTVVDHTITSCEWVDFYLLAHHVRQGC 900
ENYQPKMVVFVVQKKISTNLYLAAPQNFVTPTPGTVVDHTITSCEWVDFYLLAHHVRQGC
Sbjct: 841 ENYQPKMVVFVVQKKISTNLYLAAPQNFVTPTPGTVVDHTITSCEWVDFYLLAHHVRQGC 900
Query: 901 GIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGHILHH 960
GIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGHILHH
Sbjct: 901 GIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGHILHH 960
Query: 961 EPAIQLCENLFFL 973
EPAIQLCENLFFL
Sbjct: 961 EPAIQLCENLFFL 973
>gi|66346725 piwi-like 1 [Homo sapiens]
Length = 861
Score = 676 bits (1743), Expect = 0.0
Identities = 325/762 (42%), Positives = 482/762 (63%), Gaps = 8/762 (1%)
Query: 216 KQGSKGTPQSLGLNLVKIQCHNE-AVYQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAF 274
K GS G L N ++ + A+YQYH+ ++P +E + +R +L H+ + G AF
Sbjct: 104 KTGSSGIIVRLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGKCHAF 163
Query: 275 DGSILYLPVKLQQVLELKSQRKTDSAEISIKIQMTKILEPCSDLCIPFYNVVFRRVMKLL 334
DG+IL+LP +LQQ + + + ++ I I +T L P S C+ FYN++FRR++K++
Sbjct: 164 DGTILFLPKRLQQKVTEVFSKTRNGEDVRITITLTNELPPTSPTCLQFYNIIFRRLLKIM 223
Query: 335 DMKLVGRNFYDPTSAMVLQQHRLQIWPGYAASIRRTDGGLFLLADVSHKVIRNDCVLDVM 394
+++ +GRN+Y+P + + HRL IWPG+ SI + + + L DVSHKV+R++ VLD M
Sbjct: 224 NLQQIGRNYYNPNDPIDIPSHRLVIWPGFTTSILQYENSIMLCTDVSHKVLRSETVLDFM 283
Query: 395 HAIYQQNKEH-FQDECTKLLVGNIVITRYNNRTYRIDDVDWNKTPKDSFTMSDGKEITFL 453
Y Q +EH FQ++ +K L+G +V+T+YNN+TYR+DD+DW++ PK +F +DG E++FL
Sbjct: 284 FNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFL 343
Query: 454 EYYSKNYGITVKEEDQPLLIHRPSERQDNHGMLLKGEILLLPELSFMTGIPEKMKKDFRA 513
EYY K Y + + QP+L+ +P R+ G L G +L+PEL ++TG+ +KM+ DF
Sbjct: 344 EYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTL-PGPAMLIPELCYLTGLTDKMRNDFNV 402
Query: 514 MKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGRVLPMERI 573
MKDLA L+P+Q + L+ I KN+ EL WGL ++ GR+L E+I
Sbjct: 403 MKDLAVHTRLTPEQRQREVGRLIDYIHKNDNVQRELRDWGLSFDSNLLSFSGRILQTEKI 462
Query: 574 NLKNTSF-ITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLEKIAGPI 632
+ +F Q +W KE P I P+ W L Y +R + A L+ L K+ +
Sbjct: 463 HQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPAM 522
Query: 633 GMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQMVVCIIMGPRDDLYGAIKKLCCVQS 692
GM+M +E+ DDR E Y+R +Q + A+ Q+VVC++ R D Y AIKK C
Sbjct: 523 GMQMRKAIMIEV-DDRTEAYLRVLQQKVTAD--TQIVVCLLSSNRKDKYDAIKKYLCTDC 579
Query: 693 PVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLMVIGMDVYHDPSR 752
P PSQ V RT+G+ + ++A KI LQ+NCK+GGELW VDIPLK +M++G+D YHD +
Sbjct: 580 PTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDIPLKLVMIVGIDCYHDMTA 639
Query: 753 GMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVV 812
G RS+ GFVASIN +T+W+SR +FQ QE+VD LK+CL +L+ + N +P +I+V
Sbjct: 640 GRRSIAGFVASINEGMTRWFSRCIFQDRGQELVDGLKVCLQAALRAWNSCNEYMPSRIIV 699
Query: 813 YRDGVSDGQLKTVANYEIPQLQKCFEAF-ENYQPKMVVFVVQKKISTNLYLAAPQNFVTP 871
YRDGV DGQLKT+ NYE+PQ C ++ Y P++ V VV+K+++T + + P
Sbjct: 700 YRDGVGDGQLKTLVNYEVPQFLDCLKSIGRGYNPRLTVIVVKKRVNTRFFAQSGGRLQNP 759
Query: 872 TPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHMY 931
PGTV+D +T EW DF++++ VR G PTHY + + + L PDH+QRLT+KLCH+Y
Sbjct: 760 LPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDNSGLKPDHIQRLTYKLCHIY 819
Query: 932 WNWPGTIRVPAPCKYAHKLAFLSGHILHHEPAIQLCENLFFL 973
+NWPG IRVPAPC+YAHKLAFL G +H EP + L L++L
Sbjct: 820 YNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL 861
>gi|169217928 PREDICTED: similar to piwi like homolog 2 [Homo
sapiens]
Length = 349
Score = 594 bits (1531), Expect = e-169
Identities = 295/295 (100%), Positives = 295/295 (100%)
Query: 507 MKKDFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGR 566
MKKDFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGR
Sbjct: 1 MKKDFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGR 60
Query: 567 VLPMERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLE 626
VLPMERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLE
Sbjct: 61 VLPMERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLE 120
Query: 627 KIAGPIGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQMVVCIIMGPRDDLYGAIKK 686
KIAGPIGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQMVVCIIMGPRDDLYGAIKK
Sbjct: 121 KIAGPIGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQMVVCIIMGPRDDLYGAIKK 180
Query: 687 LCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLMVIGMDV 746
LCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLMVIGMDV
Sbjct: 181 LCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLMVIGMDV 240
Query: 747 YHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFYE 801
YHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFYE
Sbjct: 241 YHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFYE 295
>gi|221316711 piwi-like 4 [Homo sapiens]
Length = 852
Score = 566 bits (1458), Expect = e-161
Identities = 300/763 (39%), Positives = 449/763 (58%), Gaps = 13/763 (1%)
Query: 216 KQGSKGTPQSLGLNLVKIQCHNE-AVYQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAF 274
K GS G P L NL + + +YQYHVT+ P++ + +R +L H ++ AF
Sbjct: 98 KTGSSGIPVKLVTNLFNLDFPQDWQLYQYHVTYIPDLASRRLRIALLYSHSELSNKAKAF 157
Query: 275 DGSILYLPVKLQQ-VLELKSQRKTDSAEISIKIQMTKILEPCSDLCIPFYNVVFRRVMKL 333
DG+IL+L KL++ V EL S+ + I + I + + L S +CI +N++FR+++K
Sbjct: 158 DGAILFLSQKLEEKVTELSSETQRGET-IKMTITLKRELPSSSPVCIQVFNIIFRKILKK 216
Query: 334 LDMKLVGRNFYDPTSAMVLQQHRLQIWPGYAASIRRTDGGLFLLADVSHKVIRNDCVLDV 393
L M +GRNFY+P+ M + QH+L +WPG+A S+ + L ADVS+KV+RN+ VL+
Sbjct: 217 LSMYQIGRNFYNPSEPMEIPQHKLSLWPGFAISVSYFERKLLFSADVSYKVLRNETVLEF 276
Query: 394 MHAIYQQNK-EHFQDECTKLLVGNIVITRYNNRTYRIDDVDWNKTPKDSFTMSDGKEITF 452
M A+ Q+ F C K L+G IV+TRYNNRTY IDD+DW+ P +F DG EIT+
Sbjct: 277 MTALCQRTGLSCFTQTCEKQLIGLIVLTRYNNRTYSIDDIDWSVKPTHTFQKRDGTEITY 336
Query: 453 LEYYSKNYGITVKEEDQPLLIHR-PSERQDNHGMLLKGEILLLPELSFMTGIPEKMKKDF 511
++YY + Y ITV + +QP+L+ +R DN L L+PEL F+TG+ ++ DF
Sbjct: 337 VDYYKQQYDITVSDLNQPMLVSLLKKKRNDNSEAQLAH---LIPELCFLTGLTDQATSDF 393
Query: 512 RAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGRVLPME 571
+ MK +A++ LSP L L+ I +N A EL WGL + + GR++P E
Sbjct: 394 QLMKAVAEKTRLSPSGRQQRLARLVDNIQRNTNARFELETWGLHFGSQI-SLTGRIVPSE 452
Query: 572 RINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLEKIAGP 631
+I +++ +W K++ + ++ W + R A +N L ++AG
Sbjct: 453 KILMQDHICQPVSAADWSKDIRTCKILNAQSLNTWLILCSDRTEYVAESFLNCLRRVAGS 512
Query: 632 IGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQMVVCIIMGPRDDLYGAIKKLCCVQ 691
+G + P ++++++ +VR IQ + + +Q+V+CI+ + Y +IKK
Sbjct: 513 MGFNVDYPKIIKVQENPA-AFVRAIQQYVDPD--VQLVMCILPSNQKTYYDSIKKYLSSD 569
Query: 692 SPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLMVIGMDVYHDPS 751
PVPSQ V RT+ + + S+A KI +Q+ CKLGGELW V+IPLK LMV+G+DV D
Sbjct: 570 CPVPSQCVLARTLNKQGMMMSIATKIAMQMTCKLGGELWAVEIPLKSLMVVGIDVCKDAL 629
Query: 752 RGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFYEVNHCLPEKIV 811
VVG VAS+N +T+W+SR + Q ++ D LK+ + G+L K+Y+ NH LP +I+
Sbjct: 630 SKDVMVVGCVASVNPRITRWFSRCILQRTMTDVADCLKVFMTGALNKWYKYNHDLPARII 689
Query: 812 VYRDGVSDGQLKTVANYEIPQ-LQKCFEAFENYQPKMVVFVVQKKISTNLYLAAPQNFVT 870
VYR GV DGQLKT+ YE+PQ L E+ N ++ V VV+KK + +
Sbjct: 690 VYRAGVGDGQLKTLIEYEVPQLLSSVAESSSNTSSRLSVIVVRKKCMPRFFTEMNRTVQN 749
Query: 871 PTPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHM 930
P GTVVD T EW DFYL++ +G PT+Y + + L PDHMQRLTFKLCH+
Sbjct: 750 PPLGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNVIYDDNGLKPDHMQRLTFKLCHL 809
Query: 931 YWNWPGTIRVPAPCKYAHKLAFLSGHILHHEPAIQLCENLFFL 973
Y+NWPG + VPAPC+YAHKL FL +H EP+++L +LF+L
Sbjct: 810 YYNWPGIVSVPAPCQYAHKLTFLVAQSIHKEPSLELANHLFYL 852
>gi|153792298 piwi-like 3 [Homo sapiens]
Length = 882
Score = 514 bits (1323), Expect = e-145
Identities = 275/773 (35%), Positives = 444/773 (57%), Gaps = 22/773 (2%)
Query: 216 KQGSKGTPQSLGLNLVKIQCHNEAV-YQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAF 274
K GS+GT L N ++ + V Y+Y+V + P++E ++R +L H+ G F
Sbjct: 117 KTGSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIF 176
Query: 275 DGSILYL--PVKLQQVLELKSQRKTDSAEISIKIQMTKILEPCSDLCIPFYNVVFRRVMK 332
DG+ L L P+K ++V L + + D + I ++ +K L P S C+ +YN++FRR K
Sbjct: 177 DGNSLLLSRPLKERRVEWLSTTK--DKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFK 234
Query: 333 LLDMKLVGRNFYDPTSAMVLQQH--RLQIWPGYAASIRRTDGGLFLLADVSHKVIRNDCV 390
LLD + VGRN+Y A+ L +H L+IW GY S+ + + + L ADVSHK++R +
Sbjct: 235 LLDFEQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETA 294
Query: 391 LD-VMHAIYQQNKEHFQDECTKLLVGNIVITRYNNRTYRIDDVDWNKTPKDSFTMSDGKE 449
D + Q + ++E T L+G+IV+T+YNN+TYR+DD+DW + P+D+F SDG +
Sbjct: 295 YDFIKRTSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSK 354
Query: 450 ITFLEYYSKNYGITVKEEDQPLLIHRPSERQDNHGMLLKGEILLLPELSFMTGIPEKMKK 509
IT+++YY + + V + QPLL+ + ++ G + ILL+P+L MTG+ +++ K
Sbjct: 355 ITYIDYYRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQ-REPILLIPQLCHMTGLTDEICK 413
Query: 510 DFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGRVLP 569
D+ +K+LA+ LSP++ H L+ + + N+ L W L+ + + GRVL
Sbjct: 414 DYSIVKELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLK 473
Query: 570 MERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLEKIA 629
I + + +W +E+ P + +P+H W + Y + + +A L L+ +
Sbjct: 474 NANIVQGRRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVT 533
Query: 630 GPIGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQM-------VVCIIMGPRDDL-- 680
P+G+ M P +E+ D +Y+ T++ ++ M V+CI+ P DD
Sbjct: 534 APMGITMKPAEMIEVDGDA-NSYIDTLRKYTRPTLQMGMSCLLVFKVICIL--PNDDKRR 590
Query: 681 YGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLM 740
Y +IK+ C + P+PSQ V +T+ + + R++ KI Q+NCK+GG LW V+ +++ M
Sbjct: 591 YDSIKRYLCTKCPIPSQCVVKKTL-EKVQARTIVTKIAQQMNCKMGGALWKVETDVQRTM 649
Query: 741 VIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFY 800
+G+D +HD +S+ GFVAS N LTKWYS+ V Q +E+V L++CL +L +
Sbjct: 650 FVGIDCFHDIVNRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWC 709
Query: 801 EVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAFENYQPKMVVFVVQKKISTNL 860
+ +P ++VYRDGV DGQL+ + ++E ++ + + VV+K+I+T
Sbjct: 710 KNESSMPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFTLAFIVVKKRINTRF 769
Query: 861 YLAAPQNFVTPTPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYVCVLNTANLSPDHM 920
+L NF P PGTV+D +T EW DF++++ V+ G PTHY + +T LSPD +
Sbjct: 770 FLKHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTV 829
Query: 921 QRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGHILHHEPAIQLCENLFFL 973
QRLT+ LCHMY+N PG IRVPAPC YAHKLA+L G +H EP L LF+L
Sbjct: 830 QRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL 882
>gi|6912352 eukaryotic translation initiation factor 2C, 1 [Homo
sapiens]
Length = 857
Score = 157 bits (398), Expect = 3e-38
Identities = 190/806 (23%), Positives = 345/806 (42%), Gaps = 97/806 (12%)
Query: 218 GSKGTPQSLGLNLVKIQCHNEAVYQYHVTFSPN-----VECKSMRFGMLKDHQAVTGN-V 271
G+ G P L N ++ VY Y V P+ V + + + + + G+
Sbjct: 30 GTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRK 89
Query: 272 TAFDG-----SILYLPVKLQQV---LELKSQRKTDSAEISIK---IQMTKILEPC---SD 317
+DG ++ LP+ ++V + + + K ++SIK I ++L
Sbjct: 90 PVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQ 149
Query: 318 LCIPFYNV----VFRRVMKLLDMKLVGRNFYDPTSAMVLQQHRL----QIWPGYAASIRR 369
+ +P +V V R + + VGR+F+ P H L ++W G+ S+R
Sbjct: 150 IPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYY---HPLGGGREVWFGFHQSVRP 206
Query: 370 TDGGLFLLADVS-------HKVIRNDC-VLDVMHAIYQ------QNKEHFQDECTKLLVG 415
+ L DVS VI C VLD+ + Q + F E L V
Sbjct: 207 AMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKV- 265
Query: 416 NIVITRYNNRTYRIDDVDWNKTPKDSFTMS----DGKEITFLEYYSKNYGITVKEEDQPL 471
+ R YR+ +V +F + E T +Y+ + Y + +K P
Sbjct: 266 EVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPC 325
Query: 472 LIHRPSERQDNHGMLLKGEILLLPELSFMTGIPEKMKK--DFRAMKDLAQQINLSPKQHH 529
L G K L L + + G +KK D + + +P +
Sbjct: 326 L---------QVGQEQKHTYLPLEVCNIVAG-QRCIKKLTDNQTSTMIKATARSAPDRQE 375
Query: 530 SALECLLQRIAKNEAATNE--LMRWGLRLQKDVHKIEGRVLPMERINL--KNTSFITSQE 585
+ R+ KN + + + +G++++ D+ ++ GRVLP + +N + T +
Sbjct: 376 E-----ISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQ 430
Query: 586 LNWVKEVTRDPSILTIPMHFWALFYPKRAMDQA--RELVNMLEKIAGPIGMRMS-PPAWV 642
W + + + I + A F P++ + + + L KI+ GM + P +
Sbjct: 431 GVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFC 490
Query: 643 ELKD--DRIETYVRTIQSTLGAEGKIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVN 700
+ D +E R +++T +Q+++ I+ G + +Y +K++ + +Q V
Sbjct: 491 KYAQGADSVEPMFRHLKNTYSG---LQLIIVILPG-KTPVYAEVKRVGDTLLGMATQCVQ 546
Query: 701 VRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLMV-------IGMDVYHDPSRG 753
V+ + + + + L+IN KLGG + + +P ++ V +G DV H P+
Sbjct: 547 VKNVVKTSP--QTLSNLCLKINVKLGG-INNILVPHQRSAVFQQPVIFLGADVTHPPAGD 603
Query: 754 MR--SVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFYEVNHCLPEKIV 811
+ S+ V S++ +++ + V Q P QEI++ L + L +FY+ P +I+
Sbjct: 604 GKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRII 663
Query: 812 VYRDGVSDGQLKTVANYEIPQLQK-CFEAFENYQPKMVVFVVQKKISTNLYLAAPQNFVT 870
YRDGV +GQL + +YE+ ++ C + ++YQP + VVQK+ T L+ A +
Sbjct: 664 FYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIG 723
Query: 871 PT----PGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFK 926
+ GT VD IT DFYL +H QG P+HY + + + D +Q LT++
Sbjct: 724 KSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQ 783
Query: 927 LCHMYWNWPGTIRVPAPCKYAHKLAF 952
LCH Y ++ +PAP YA +AF
Sbjct: 784 LCHTYVRCTRSVSIPAPAYYARLVAF 809
>gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo
sapiens]
Length = 859
Score = 148 bits (374), Expect = 2e-35
Identities = 195/842 (23%), Positives = 345/842 (40%), Gaps = 103/842 (12%)
Query: 177 PSRGPPQLSSPPALPQSPLHSPDRPLVLTVEHKEKELIVKQGSKGTPQSLGLNLVKIQCH 236
P+ PP + PP + P RP G+ G L N ++
Sbjct: 7 PALAPP--APPPPIQGYAFKPPPRP--------------DFGTSGRTIKLQANFFEMDIP 50
Query: 237 NEAVYQYHVTFSPNVECKSMRFGMLKDH-------QAVTGNVTAFDG-----SILYLPV- 283
+Y Y + P +C + +H Q FDG + + LP+
Sbjct: 51 KIDIYHYELDIKPE-KCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIG 109
Query: 284 --KLQQVLELKSQRKTDSAEISIKIQMTKILEPCSDLC------IPFYNV----VFRRVM 331
K++ + L + K ++SIK L+ D +PF + V R +
Sbjct: 110 RDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHL 169
Query: 332 KLLDMKLVGRNFYDPTSAMV--LQQHRLQIWPGYAASIRRTDGGLFLLADVS-------H 382
+ VGR+F+ + L R ++W G+ S+R + + L DVS
Sbjct: 170 PSMRYTPVGRSFFTASEGCSNPLGGGR-EVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQ 228
Query: 383 KVIRNDCVLDVMHAIYQQNK---EHFQDECTKLLVG-NIVITRYNN--RTYRIDDVDWNK 436
VI C + +I +Q K + + + TK + G + IT R YR+ +V
Sbjct: 229 PVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRP 288
Query: 437 TPKDSFTMSDGK----EITFLEYYSKNYGITVKEEDQPLLIHRPSERQDNHGMLLKGEIL 492
+F + E T +Y+ + + ++ P L G K L
Sbjct: 289 ASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCL---------QVGQEQKHTYL 339
Query: 493 LLPELSFMTGIPEKMKKDFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMR- 551
L + + G K + + S + L++ + N T+ +R
Sbjct: 340 PLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFN---TDPYVRE 396
Query: 552 WGLRLQKDVHKIEGRVLPMERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWAL--F 609
+G+ ++ ++ + GRVL I + + + V ++ I + WA+ F
Sbjct: 397 FGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACF 456
Query: 610 YPKRAMDQA--RELVNMLEKIAGPIGMRMS-PPAWVELKD--DRIETYVRTIQSTLGAEG 664
P+R + + L KI+ GM + P + + D +E R +++T
Sbjct: 457 APQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAG-- 514
Query: 665 KIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCK 724
+Q+VV I+ G + +Y +K++ + +Q V ++ + + T + L+IN K
Sbjct: 515 -LQLVVVILPG-KTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTP--QTLSNLCLKINVK 570
Query: 725 LGGELWGVDIPL-------KQLMVIGMDVYHDPSRGMR--SVVGFVASINLTLTKWYSRV 775
LGG + + +P + ++ +G DV H P+ + S+ V S++ ++ + V
Sbjct: 571 LGG-VNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATV 629
Query: 776 VFQMPHQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQK 835
Q QEI+ L + L +FY+ P +I+ YRDGVS+GQ + V ++E+ +++
Sbjct: 630 RVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIRE 689
Query: 836 -CFEAFENYQPKMVVFVVQKKISTNLYLAAPQNFVTPT----PGTVVDHTITSCEWVDFY 890
C + ++YQP + VVQK+ T L+ V + GT VD IT DFY
Sbjct: 690 ACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFY 749
Query: 891 LLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKL 950
L +H QG P+HY + + S D +Q LT++LCH Y ++ +PAP YAH +
Sbjct: 750 LCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLV 809
Query: 951 AF 952
AF
Sbjct: 810 AF 811
>gi|29294647 eukaryotic translation initiation factor 2C, 3 isoform
a [Homo sapiens]
Length = 860
Score = 147 bits (371), Expect = 5e-35
Identities = 164/659 (24%), Positives = 292/659 (44%), Gaps = 69/659 (10%)
Query: 339 VGRNFYDPTSAMVLQQHRL----QIWPGYAASIRRTDGGLFLLADVS-------HKVIRN 387
VGR+F+ SA H L ++W G+ S+R + L DVS VI+
Sbjct: 178 VGRSFF---SAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQF 234
Query: 388 DCVLDVMHAIYQQNK---EHFQDECTKLLVG-NIVITRYNN--RTYRIDDVDWNKTPKDS 441
C + +H I +Q + + + + TK + G + +T R YR+ +V +
Sbjct: 235 MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT 294
Query: 442 FTMS--DGKEI--TFLEYYSKNYGITVKEEDQPLLIHRPSERQDNHGMLLKGEILLLPEL 497
F + +G+ + T +Y+ + Y + +K P L G K L L
Sbjct: 295 FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCL---------QVGQEQKHTYLPLEVC 345
Query: 498 SFMTGIPEKMKKDFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQ 557
+ + G K + + S + L++ + N + + +++
Sbjct: 346 NIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVR--SANYETDPFVQEFQFKVR 403
Query: 558 KDVHKIEGRVLPMERINL--KNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAM 615
++ + GRVLP + +N + T W + + + I M A F +R
Sbjct: 404 DEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQR-- 461
Query: 616 DQARELV-----NMLEKIAGPIGMRMS-PPAWVELKD--DRIETYVRTIQSTLGAEGKIQ 667
Q RE + + L KI+ GM + P + + D +E R +++T +Q
Sbjct: 462 -QCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSG---LQ 517
Query: 668 MVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGG 727
+++ I+ G + +Y +K++ + +Q V V+ + + + + L+IN KLGG
Sbjct: 518 LIIVILPG-KTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSP--QTLSNLCLKINVKLGG 574
Query: 728 ELWGVDIPLKQ-------LMVIGMDVYHDPSRGMR--SVVGFVASINLTLTKWYSRVVFQ 778
+ + +P ++ ++ +G DV H P+ + S+ V S++ +++ + V Q
Sbjct: 575 -INNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQ 633
Query: 779 MPHQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQK-CF 837
P QEI+ L + L +FY+ P +I+ YRDGVS+GQ + V YE+ +++ C
Sbjct: 634 RPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACI 693
Query: 838 EAFENYQPKMVVFVVQKKISTNLYLAAPQNFVTPT----PGTVVDHTITSCEWVDFYLLA 893
++YQP + VVQK+ T L+ A V + GT VD IT DFYL +
Sbjct: 694 SLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCS 753
Query: 894 HHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAF 952
H QG P+HY + + + D +Q LT++LCH Y ++ +PAP YAH +AF
Sbjct: 754 HAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 812
>gi|29029593 eukaryotic translation initiation factor 2C, 4 [Homo
sapiens]
Length = 861
Score = 143 bits (360), Expect = 9e-34
Identities = 164/667 (24%), Positives = 287/667 (43%), Gaps = 73/667 (10%)
Query: 339 VGRNFYDPTSAMVLQQHRL----QIWPGYAASIRRTDGGLFLLADVS-------HKVIRN 387
VGR+F+ P H L ++W G+ S+R + L DVS +I
Sbjct: 167 VGRSFFSPPEGYY---HPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPIIEF 223
Query: 388 DC-VLDVMHAIYQQNK---EHFQDECTKLLVG-NIVITRYNN--RTYRIDDVDWNKTPKD 440
C VLD+ + I +Q K + + + TK + G + +T R YR+ +V
Sbjct: 224 MCEVLDIQN-INEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQ 282
Query: 441 SFTMS----DGKEITFLEYYSKNYGITVKEEDQPLLIHRPSERQDNHGMLLKGEILLLPE 496
+F + E T +Y+ + Y + +K P L G K L L
Sbjct: 283 TFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCL---------QVGQEQKHTYLPLEV 333
Query: 497 LSFMTGIPEKMKKDFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRL 556
+ + G K + + S + L++ + L +G+ +
Sbjct: 334 CNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVV 393
Query: 557 QKDVHKIEGRVLPMERINL--KNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRA 614
++ ++ GRVLP + +N + T + W + + + I + A F P++
Sbjct: 394 HNEMTELTGRVLPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQ 453
Query: 615 M--DQARELVNMLEKIAGPIGMRMS-PPAWVELKD--DRIETYVRTIQSTLGAEGKIQMV 669
D + + L KI+ GM + P + + D +E + ++ T +Q++
Sbjct: 454 CREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVG---LQLI 510
Query: 670 VCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGEL 729
V I+ G + +Y +K++ + +Q V V+ + + + + L+IN KLGG +
Sbjct: 511 VVILPG-KTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSP--QTLSNLCLKINAKLGG-I 566
Query: 730 WGVDIPLKQ-------LMVIGMDVYHDPSRGMR--SVVGFVASINLTLTKWYSRVVFQMP 780
V +P ++ ++ +G DV H P+ + S+ V S++ +++ + V Q
Sbjct: 567 NNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTS 626
Query: 781 HQEI----------VDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEI 830
QEI + L + L +FY+ P +I+ YR GVS+GQ+K VA E+
Sbjct: 627 RQEISQELLYSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPEL 686
Query: 831 PQLQK-CFEAFENYQPKMVVFVVQKKISTNLYLAAPQNFVTPT----PGTVVDHTITSCE 885
++K C E+Y+P + VVQK+ T L+ A V + GT VD TIT
Sbjct: 687 IAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKTERVGKSGNVPAGTTVDSTITHPS 746
Query: 886 WVDFYLLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCK 945
DFYL +H QG P+HY + + + D +Q LT++LCH Y ++ +PAP
Sbjct: 747 EFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAY 806
Query: 946 YAHKLAF 952
YA +AF
Sbjct: 807 YARLVAF 813
>gi|29337286 eukaryotic translation initiation factor 2C, 3 isoform
b [Homo sapiens]
Length = 626
Score = 142 bits (357), Expect = 2e-33
Identities = 117/422 (27%), Positives = 205/422 (48%), Gaps = 34/422 (8%)
Query: 555 RLQKDVHKIEGRVLPMERINL--KNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPK 612
+++ ++ + GRVLP + +N + T W + + + I M A F +
Sbjct: 167 KVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQ 226
Query: 613 RAMDQARELV-----NMLEKIAGPIGMRMS-PPAWVELKD--DRIETYVRTIQSTLGAEG 664
R Q RE + + L KI+ GM + P + + D +E R +++T
Sbjct: 227 R---QCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSG-- 281
Query: 665 KIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCK 724
+Q+++ I+ G + +Y +K++ + +Q V V+ + + + + L+IN K
Sbjct: 282 -LQLIIVILPG-KTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSP--QTLSNLCLKINVK 337
Query: 725 LGGELWGVDIPLKQ-------LMVIGMDVYHDPSRGMR--SVVGFVASINLTLTKWYSRV 775
LGG + + +P ++ ++ +G DV H P+ + S+ V S++ +++ + V
Sbjct: 338 LGG-INNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATV 396
Query: 776 VFQMPHQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQK 835
Q P QEI+ L + L +FY+ P +I+ YRDGVS+GQ + V YE+ +++
Sbjct: 397 RVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIRE 456
Query: 836 -CFEAFENYQPKMVVFVVQKKISTNLYLAAPQNFVTPT----PGTVVDHTITSCEWVDFY 890
C ++YQP + VVQK+ T L+ A V + GT VD IT DFY
Sbjct: 457 ACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFY 516
Query: 891 LLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKL 950
L +H QG P+HY + + + D +Q LT++LCH Y ++ +PAP YAH +
Sbjct: 517 LCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLV 576
Query: 951 AF 952
AF
Sbjct: 577 AF 578
>gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]
Length = 778
Score = 37.0 bits (84), Expect = 0.090
Identities = 33/96 (34%), Positives = 41/96 (42%), Gaps = 14/96 (14%)
Query: 103 GLSANLVRKDREELSPTFWDPKVLAAGDSKMAETSVGWSRTLGRGSSDASLLPLGRAAGG 162
GLS++ + R SP F AGD +R G +S LP GG
Sbjct: 439 GLSSSPLSSPR---SPVFSFSPEPGAGDE---------ARGGGSPTSKTQTLPSRGPRGG 486
Query: 163 ISREVDKPPCTFSTPSRGPPQLSSPPALPQSPLHSP 198
+ E PP STP GPP SP + +PLHSP
Sbjct: 487 GAGEQPPPPSARSTPLPGPP--GSPRSSGGTPLHSP 520
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 34.7 bits (78), Expect = 0.45
Identities = 23/56 (41%), Positives = 29/56 (51%), Gaps = 5/56 (8%)
Query: 145 GRGSSD---ASLLPLGRAAGGISREVDKPPCTFSTPSRGPPQLS-SPPALPQSPLH 196
GR S+D + LG A G S PPC +P RG PQL PPAL + P++
Sbjct: 1942 GRVSTDDWPCDWVALG-ACGSASNIPIPPPCLTPSPERGSPQLDCGPPALQEMPIN 1996
>gi|14251215 Kruppel-like factor 5 [Homo sapiens]
Length = 457
Score = 33.5 bits (75), Expect = 0.99
Identities = 16/33 (48%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
Query: 170 PPCTFSTPSRGPPQLSS--PPALPQSPLHSPDR 200
PPCT++ PS+ PQ ++ PP+ P S SPDR
Sbjct: 282 PPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDR 314
>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
Length = 946
Score = 33.5 bits (75), Expect = 0.99
Identities = 16/44 (36%), Positives = 28/44 (63%), Gaps = 2/44 (4%)
Query: 594 RDPSILTIPMHFWALFYPKRAMDQARELVNMLEKIAGPIGMRMS 637
++PS+L+ P+H WA+ + Q+RE + E +AGP+ R+S
Sbjct: 92 KEPSLLS-PLHCWAVLL-QHTRQQSRESAALSEVLAGPLAQRLS 133
>gi|19913396 smoothelin isoform b [Homo sapiens]
Length = 915
Score = 33.1 bits (74), Expect = 1.3
Identities = 42/164 (25%), Positives = 60/164 (36%), Gaps = 6/164 (3%)
Query: 21 AVRMPGCWPQAS-KPLDPALGRGAPAGRGHVFGKPEEPSTQRGPAQRESVGLVSMFRGLG 79
A R+ PQA+ PL PA G P+ S+ RGP+ S RG+
Sbjct: 344 AARLQDGTPQAALSPLTPARLLG-PSLTSTTPASSSSGSSSRGPSDTSS-RFSKEQRGVA 401
Query: 80 IETVSKTPLKREMLPSGRGILGRGL---SANLVRKDREELSPTFWDPKVLAAGDSKMAET 136
+E P GRG+ R L + V + E +P G S
Sbjct: 402 QPLAQLRSCPQEEGPRGRGLAARPLENRAGGPVARSEEPGAPLPVAVGTAEPGGSMKTTF 461
Query: 137 SVGWSRTLGRGSSDASLLPLGRAAGGISREVDKPPCTFSTPSRG 180
++ G+ S+ LLP G ++ + PP ST S G
Sbjct: 462 TIEIKDGRGQASTGRVLLPTGNQRAELTLGLRAPPTLLSTSSGG 505
>gi|30089966 CDC42 effector protein 5 [Homo sapiens]
Length = 148
Score = 33.1 bits (74), Expect = 1.3
Identities = 17/41 (41%), Positives = 21/41 (51%)
Query: 163 ISREVDKPPCTFSTPSRGPPQLSSPPALPQSPLHSPDRPLV 203
+SR PP P G P+ PPA+PQS SP PL+
Sbjct: 49 LSRHGGGPPPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLL 89
>gi|19913394 smoothelin isoform c [Homo sapiens]
Length = 917
Score = 33.1 bits (74), Expect = 1.3
Identities = 42/164 (25%), Positives = 60/164 (36%), Gaps = 6/164 (3%)
Query: 21 AVRMPGCWPQAS-KPLDPALGRGAPAGRGHVFGKPEEPSTQRGPAQRESVGLVSMFRGLG 79
A R+ PQA+ PL PA G P+ S+ RGP+ S RG+
Sbjct: 344 AARLQDGTPQAALSPLTPARLLG-PSLTSTTPASSSSGSSSRGPSDTSS-RFSKEQRGVA 401
Query: 80 IETVSKTPLKREMLPSGRGILGRGL---SANLVRKDREELSPTFWDPKVLAAGDSKMAET 136
+E P GRG+ R L + V + E +P G S
Sbjct: 402 QPLAQLRSCPQEEGPRGRGLAARPLENRAGGPVARSEEPGAPLPVAVGTAEPGGSMKTTF 461
Query: 137 SVGWSRTLGRGSSDASLLPLGRAAGGISREVDKPPCTFSTPSRG 180
++ G+ S+ LLP G ++ + PP ST S G
Sbjct: 462 TIEIKDGRGQASTGRVLLPTGNQRAELTLGLRAPPTLLSTSSGG 505
>gi|19913398 smoothelin isoform a [Homo sapiens]
Length = 940
Score = 33.1 bits (74), Expect = 1.3
Identities = 42/164 (25%), Positives = 60/164 (36%), Gaps = 6/164 (3%)
Query: 21 AVRMPGCWPQAS-KPLDPALGRGAPAGRGHVFGKPEEPSTQRGPAQRESVGLVSMFRGLG 79
A R+ PQA+ PL PA G P+ S+ RGP+ S RG+
Sbjct: 344 AARLQDGTPQAALSPLTPARLLG-PSLTSTTPASSSSGSSSRGPSDTSS-RFSKEQRGVA 401
Query: 80 IETVSKTPLKREMLPSGRGILGRGL---SANLVRKDREELSPTFWDPKVLAAGDSKMAET 136
+E P GRG+ R L + V + E +P G S
Sbjct: 402 QPLAQLRSCPQEEGPRGRGLAARPLENRAGGPVARSEEPGAPLPVAVGTAEPGGSMKTTF 461
Query: 137 SVGWSRTLGRGSSDASLLPLGRAAGGISREVDKPPCTFSTPSRG 180
++ G+ S+ LLP G ++ + PP ST S G
Sbjct: 462 TIEIKDGRGQASTGRVLLPTGNQRAELTLGLRAPPTLLSTSSGG 505
>gi|209954778 neurotrophic factor artemin isoform 3 precursor [Homo
sapiens]
Length = 228
Score = 32.7 bits (73), Expect = 1.7
Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 27/122 (22%)
Query: 79 GIETVSKTPLKREMLPSGRGILGRGLSANLVRKDREELSPTFWDPKVLAAGDSKMAETSV 138
G+ T+S P R+ P G LSA P W A S +AE S+
Sbjct: 7 GLSTLSHCPWPRQQAPLG-------LSAQ----------PALWPTLAALALLSSVAEASL 49
Query: 139 GW---SRTLGRG-----SSDASLLPLGRAAGGISREVDKPPCTFSTPSRGPPQLSSPPAL 190
G S G +S A LP GR A S +PP S P+ PP + P AL
Sbjct: 50 GSAPRSPAPREGPPPVLASPAGHLPGGRTARWCSGRARRPPPQPSRPA--PPPPAPPSAL 107
Query: 191 PQ 192
P+
Sbjct: 108 PR 109
>gi|209977029 neurotrophic factor artemin isoform 3 precursor [Homo
sapiens]
Length = 228
Score = 32.7 bits (73), Expect = 1.7
Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 27/122 (22%)
Query: 79 GIETVSKTPLKREMLPSGRGILGRGLSANLVRKDREELSPTFWDPKVLAAGDSKMAETSV 138
G+ T+S P R+ P G LSA P W A S +AE S+
Sbjct: 7 GLSTLSHCPWPRQQAPLG-------LSAQ----------PALWPTLAALALLSSVAEASL 49
Query: 139 GW---SRTLGRG-----SSDASLLPLGRAAGGISREVDKPPCTFSTPSRGPPQLSSPPAL 190
G S G +S A LP GR A S +PP S P+ PP + P AL
Sbjct: 50 GSAPRSPAPREGPPPVLASPAGHLPGGRTARWCSGRARRPPPQPSRPA--PPPPAPPSAL 107
Query: 191 PQ 192
P+
Sbjct: 108 PR 109
>gi|239753758 PREDICTED: hypothetical protein LOC401106 [Homo
sapiens]
Length = 297
Score = 32.3 bits (72), Expect = 2.2
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 12/75 (16%)
Query: 134 AETSVGWSRTLGRGSSDASLLPLGRAAGGISREVDKPPCTFSTPSRGPPQLSSPPALPQS 193
A + G SR G G+ RA G+ R + +PP F+T R + PP+ P
Sbjct: 117 ARSRCGESRQAGGGA---------RAGSGLPRRMPRPPIAFATLERAKERKRQPPSPPPK 167
Query: 194 PLHSPDRPLVLTVEH 208
D+ L + +H
Sbjct: 168 ---QTDKKLSFSYDH 179
>gi|169166137 PREDICTED: hypothetical protein LOC401106 [Homo
sapiens]
Length = 297
Score = 32.3 bits (72), Expect = 2.2
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 12/75 (16%)
Query: 134 AETSVGWSRTLGRGSSDASLLPLGRAAGGISREVDKPPCTFSTPSRGPPQLSSPPALPQS 193
A + G SR G G+ RA G+ R + +PP F+T R + PP+ P
Sbjct: 117 ARSRCGESRQAGGGA---------RAGSGLPRRMPRPPIAFATLERAKERKRQPPSPPPK 167
Query: 194 PLHSPDRPLVLTVEH 208
D+ L + +H
Sbjct: 168 ---QTDKKLSFSYDH 179
>gi|169165128 PREDICTED: hypothetical protein LOC401106 [Homo
sapiens]
Length = 297
Score = 32.3 bits (72), Expect = 2.2
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 12/75 (16%)
Query: 134 AETSVGWSRTLGRGSSDASLLPLGRAAGGISREVDKPPCTFSTPSRGPPQLSSPPALPQS 193
A + G SR G G+ RA G+ R + +PP F+T R + PP+ P
Sbjct: 117 ARSRCGESRQAGGGA---------RAGSGLPRRMPRPPIAFATLERAKERKRQPPSPPPK 167
Query: 194 PLHSPDRPLVLTVEH 208
D+ L + +H
Sbjct: 168 ---QTDKKLSFSYDH 179
>gi|29294649 dicer1 [Homo sapiens]
Length = 1922
Score = 32.0 bits (71), Expect = 2.9
Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
Query: 417 IVITRYNN----RTYRIDDVDWNKTPKDSFTMSDGKEITFLEYYSKNYGITVKEEDQPLL 472
++I RY N + + DV + TP F + + TF EYY Y + + +QPLL
Sbjct: 931 VIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYE--TFAEYYKTKYNLDLTNLNQPLL 988
>gi|29294651 dicer1 [Homo sapiens]
Length = 1922
Score = 32.0 bits (71), Expect = 2.9
Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 6/60 (10%)
Query: 417 IVITRYNN----RTYRIDDVDWNKTPKDSFTMSDGKEITFLEYYSKNYGITVKEEDQPLL 472
++I RY N + + DV + TP F + + TF EYY Y + + +QPLL
Sbjct: 931 VIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYE--TFAEYYKTKYNLDLTNLNQPLL 988
>gi|217035095 tripartite motif-containing 62 [Homo sapiens]
Length = 475
Score = 32.0 bits (71), Expect = 2.9
Identities = 17/56 (30%), Positives = 32/56 (57%)
Query: 494 LPELSFMTGIPEKMKKDFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNEL 549
L E +TGI + + R +KD Q + S ++H AL+ L +++A+ +++T L
Sbjct: 119 LHEQHQVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSL 174
>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
sapiens]
Length = 1484
Score = 32.0 bits (71), Expect = 2.9
Identities = 27/108 (25%), Positives = 41/108 (37%), Gaps = 13/108 (12%)
Query: 13 PIHPSQCQAVRMPGCWPQASKPLD-------PALGRGAPAGRGHVFGKPEEPSTQRGPAQ 65
P HP Q R+PG +PQ + P+ PALG A +PE + P
Sbjct: 921 PYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQAEPLPGL 980
Query: 66 RESVGLVSMFRGLGIETVS------KTPLKREMLPSGRGILGRGLSAN 107
E V G+ + + +T R+ P R +G L ++
Sbjct: 981 EEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSS 1028
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 31.6 bits (70), Expect = 3.8
Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 4/37 (10%)
Query: 169 KPPCTFSTPSRGPPQLSSPPALPQSP----LHSPDRP 201
+PP + P PP L + PA P SP LH P +P
Sbjct: 1306 QPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKP 1342
>gi|21389315 solute carrier family 25 (mitochondrial carrier;
citrate transporter), member 1 precursor [Homo sapiens]
Length = 311
Score = 31.6 bits (70), Expect = 3.8
Identities = 37/146 (25%), Positives = 63/146 (43%), Gaps = 24/146 (16%)
Query: 208 HKEKELIVKQGSKGTPQSLGLNLVKIQCHNEAVYQYHVTF--------SPNVECKSMRFG 259
H +E++ +QG KGT Q L ++K Q N+A+ + +T +PN + G
Sbjct: 166 HGVREIVREQGLKGTYQGLTATVLK-QGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITG 224
Query: 260 MLKDHQAVTGNVTAFDGSILYLPVKLQQVLELKSQRKTDSAEISI----------KIQMT 309
+ A+ G + F + L + Q LE R T + I K +
Sbjct: 225 VF---GAIAGAASVFGNTPLDVIKTRMQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVP 281
Query: 310 KILEPCSDLCIPFYNVVFRRVMKLLD 335
++ C D+ I F V++ V+KLL+
Sbjct: 282 RLGRVCLDVAIVF--VIYDEVVKLLN 305
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,043,133
Number of Sequences: 37866
Number of extensions: 1907788
Number of successful extensions: 6294
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 6212
Number of HSP's gapped (non-prelim): 99
length of query: 973
length of database: 18,247,518
effective HSP length: 112
effective length of query: 861
effective length of database: 14,006,526
effective search space: 12059618886
effective search space used: 12059618886
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.