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Search of human proteins with 24431935
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24431935 reticulon 4 isoform A [Homo sapiens]
(1192 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24431935 reticulon 4 isoform A [Homo sapiens] 2319 0.0
gi|47519562 reticulon 4 isoform E [Homo sapiens] 1901 0.0
gi|47519490 reticulon 4 isoform D [Homo sapiens] 418 e-116
gi|24431933 reticulon 4 isoform B [Homo sapiens] 383 e-106
gi|5902016 reticulon 4 isoform C [Homo sapiens] 363 e-100
gi|10863935 reticulon 1 isoform A [Homo sapiens] 271 4e-72
gi|45827778 reticulon 1 isoform B [Homo sapiens] 270 5e-72
gi|45827776 reticulon 1 isoform C [Homo sapiens] 269 1e-71
gi|41393608 reticulon 3 isoform b [Homo sapiens] 257 5e-68
gi|5174655 reticulon 3 isoform a [Homo sapiens] 246 1e-64
gi|41393604 reticulon 3 isoform c [Homo sapiens] 245 2e-64
gi|41393606 reticulon 3 isoform d [Homo sapiens] 209 1e-53
gi|5032055 reticulon 2 isoform A [Homo sapiens] 188 2e-47
gi|46255005 reticulon 2 isoform B [Homo sapiens] 187 5e-47
gi|46255007 reticulon 2 isoform C [Homo sapiens] 187 7e-47
gi|153792074 proline rich 12 [Homo sapiens] 78 6e-14
gi|110349719 titin isoform N2-A [Homo sapiens] 68 6e-11
gi|33356148 formin-like 1 [Homo sapiens] 67 8e-11
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 67 1e-10
gi|210032580 SET domain containing 1B [Homo sapiens] 67 1e-10
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 66 2e-10
gi|47132519 Ras association and pleckstrin homology domains 1 is... 65 4e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 5e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 65 5e-10
gi|7706501 WW domain binding protein 11 [Homo sapiens] 65 5e-10
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 64 7e-10
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 64 9e-10
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 64 1e-09
gi|55741677 SET domain containing 1A [Homo sapiens] 62 2e-09
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 62 3e-09
>gi|24431935 reticulon 4 isoform A [Homo sapiens]
Length = 1192
Score = 2319 bits (6009), Expect = 0.0
Identities = 1192/1192 (100%), Positives = 1192/1192 (100%)
Query: 1 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA 60
MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA
Sbjct: 1 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA 60
Query: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP 120
AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP
Sbjct: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP 120
Query: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG
Sbjct: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
Query: 181 SSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSP 240
SSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSP
Sbjct: 181 SSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSP 240
Query: 241 LSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEM 300
LSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEM
Sbjct: 241 LSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEM 300
Query: 301 GSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVV 360
GSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVV
Sbjct: 301 GSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVV 360
Query: 361 SSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKV 420
SSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKV
Sbjct: 361 SSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKV 420
Query: 421 DKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIF 480
DKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIF
Sbjct: 421 DKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIF 480
Query: 481 PLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE 540
PLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE
Sbjct: 481 PLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE 540
Query: 541 EVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSF 600
EVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSF
Sbjct: 541 EVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSF 600
Query: 601 EESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYE 660
EESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYE
Sbjct: 601 EESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYE 660
Query: 661 EAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSE 720
EAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSE
Sbjct: 661 EAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSE 720
Query: 721 MAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMI 780
MAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMI
Sbjct: 721 MAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMI 780
Query: 781 EYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVY 840
EYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVY
Sbjct: 781 EYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVY 840
Query: 841 SNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEI 900
SNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEI
Sbjct: 841 SNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEI 900
Query: 901 ANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALAT 960
ANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALAT
Sbjct: 901 ANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALAT 960
Query: 961 QAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVV 1020
QAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVV
Sbjct: 961 QAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVV 1020
Query: 1021 FGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESE 1080
FGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESE
Sbjct: 1021 FGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESE 1080
Query: 1081 VAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTL 1140
VAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTL
Sbjct: 1081 VAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTL 1140
Query: 1141 LILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE 1192
LILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
Sbjct: 1141 LILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE 1192
>gi|47519562 reticulon 4 isoform E [Homo sapiens]
Length = 986
Score = 1901 bits (4924), Expect = 0.0
Identities = 986/986 (100%), Positives = 986/986 (100%)
Query: 207 MDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQ 266
MDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQ
Sbjct: 1 MDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQ 60
Query: 267 ENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVANPREEIIVK 326
ENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVANPREEIIVK
Sbjct: 61 ENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVANPREEIIVK 120
Query: 327 NKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAKDSFNEKRVAVEAPMREEYAD 386
NKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAKDSFNEKRVAVEAPMREEYAD
Sbjct: 121 NKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAKDSFNEKRVAVEAPMREEYAD 180
Query: 387 FKPFERVWEVKDSKEDSDMLAAGGKIESNLESKVDKKCFADSLEQTNHEKDSESSNDDTS 446
FKPFERVWEVKDSKEDSDMLAAGGKIESNLESKVDKKCFADSLEQTNHEKDSESSNDDTS
Sbjct: 181 FKPFERVWEVKDSKEDSDMLAAGGKIESNLESKVDKKCFADSLEQTNHEKDSESSNDDTS 240
Query: 447 FPSTPEGIKDRSGAYITCAPFNPAATESIATNIFPLLGDPTSENKTDEKKIEEKKAQIVT 506
FPSTPEGIKDRSGAYITCAPFNPAATESIATNIFPLLGDPTSENKTDEKKIEEKKAQIVT
Sbjct: 241 FPSTPEGIKDRSGAYITCAPFNPAATESIATNIFPLLGDPTSENKTDEKKIEEKKAQIVT 300
Query: 507 EKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEV 566
EKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEV
Sbjct: 301 EKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEV 360
Query: 567 TGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAVPS 626
TGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAVPS
Sbjct: 361 TGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAVPS 420
Query: 627 AGASVIQPSSSPLEASSVNYESIKHEPENPPPYEEAMSVSLKKVSGIKEEIKEPENINAA 686
AGASVIQPSSSPLEASSVNYESIKHEPENPPPYEEAMSVSLKKVSGIKEEIKEPENINAA
Sbjct: 421 AGASVIQPSSSPLEASSVNYESIKHEPENPPPYEEAMSVSLKKVSGIKEEIKEPENINAA 480
Query: 687 LQETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKVEQPVPDHSELVEDSSPDSEPVD 746
LQETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKVEQPVPDHSELVEDSSPDSEPVD
Sbjct: 481 LQETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKVEQPVPDHSELVEDSSPDSEPVD 540
Query: 747 LFSDDSIPDVPQKQDETVMLVKESLTETSFESMIEYENKEKLSALPPEGGKPYLESFKLS 806
LFSDDSIPDVPQKQDETVMLVKESLTETSFESMIEYENKEKLSALPPEGGKPYLESFKLS
Sbjct: 541 LFSDDSIPDVPQKQDETVMLVKESLTETSFESMIEYENKEKLSALPPEGGKPYLESFKLS 600
Query: 807 LDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVYSNDDLFISKEAQIRETETFSDSSPIE 866
LDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVYSNDDLFISKEAQIRETETFSDSSPIE
Sbjct: 601 LDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVYSNDDLFISKEAQIRETETFSDSSPIE 660
Query: 867 IIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEIANAPDGAGSLPCTELPHDLSLKNIQP 926
IIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEIANAPDGAGSLPCTELPHDLSLKNIQP
Sbjct: 661 IIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEIANAPDGAGSLPCTELPHDLSLKNIQP 720
Query: 927 KVEEKISFSDDFSKNGSATSKVLLLPPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTE 986
KVEEKISFSDDFSKNGSATSKVLLLPPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTE
Sbjct: 721 KVEEKISFSDDFSKNGSATSKVLLLPPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTE 780
Query: 987 KEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALA 1046
KEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALA
Sbjct: 781 KEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALA 840
Query: 1047 LLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKEL 1106
LLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKEL
Sbjct: 841 LLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKEL 900
Query: 1107 RRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYL 1166
RRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYL
Sbjct: 901 RRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYL 960
Query: 1167 GLANKNVKDAMAKIQAKIPGLKRKAE 1192
GLANKNVKDAMAKIQAKIPGLKRKAE
Sbjct: 961 GLANKNVKDAMAKIQAKIPGLKRKAE 986
>gi|47519490 reticulon 4 isoform D [Homo sapiens]
Length = 392
Score = 418 bits (1074), Expect = e-116
Identities = 204/204 (100%), Positives = 204/204 (100%)
Query: 1 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA 60
MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA
Sbjct: 1 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA 60
Query: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP 120
AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP
Sbjct: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP 120
Query: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG
Sbjct: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
Query: 181 SSGSVDETLFALPAASEPVIRSSA 204
SSGSVDETLFALPAASEPVIRSSA
Sbjct: 181 SSGSVDETLFALPAASEPVIRSSA 204
Score = 364 bits (935), Expect = e-100
Identities = 199/250 (79%), Positives = 210/250 (84%), Gaps = 11/250 (4%)
Query: 952 PPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPS---------AIFSAELSK 1002
PP ++++ QAE + P A P+ ++ S S A +
Sbjct: 145 PPPPASVSPQAE--PVWTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEPVIRS 202
Query: 1003 TSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQ 1062
++VVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQ
Sbjct: 203 SAVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQ 262
Query: 1063 AIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFA 1122
AIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFA
Sbjct: 263 AIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFA 322
Query: 1123 VLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQA 1182
VLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQA
Sbjct: 323 VLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQA 382
Query: 1183 KIPGLKRKAE 1192
KIPGLKRKAE
Sbjct: 383 KIPGLKRKAE 392
>gi|24431933 reticulon 4 isoform B [Homo sapiens]
Length = 373
Score = 383 bits (984), Expect = e-106
Identities = 185/185 (100%), Positives = 185/185 (100%)
Query: 1 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA 60
MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA
Sbjct: 1 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA 60
Query: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP 120
AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP
Sbjct: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP 120
Query: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG
Sbjct: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
Query: 181 SSGSV 185
SSGSV
Sbjct: 181 SSGSV 185
Score = 363 bits (933), Expect = e-100
Identities = 198/241 (82%), Positives = 206/241 (85%), Gaps = 12/241 (4%)
Query: 952 PPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYW 1011
PP ++++ QAE + P A P+ ++ S S VVDLLYW
Sbjct: 145 PPPPASVSPQAE--PVWTPPAPAPAAPPSTPAAPKRRGSSGSV----------VVDLLYW 192
Query: 1012 RDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGH 1071
RDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGH
Sbjct: 193 RDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGH 252
Query: 1072 PFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYV 1131
PFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYV
Sbjct: 253 PFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYV 312
Query: 1132 GALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKA 1191
GALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKA
Sbjct: 313 GALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKA 372
Query: 1192 E 1192
E
Sbjct: 373 E 373
>gi|5902016 reticulon 4 isoform C [Homo sapiens]
Length = 199
Score = 363 bits (931), Expect = e-100
Identities = 189/191 (98%), Positives = 189/191 (98%)
Query: 1002 KTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVI 1061
K VVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVI
Sbjct: 9 KDKVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVI 68
Query: 1062 QAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKF 1121
QAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKF
Sbjct: 69 QAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKF 128
Query: 1122 AVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQ 1181
AVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQ
Sbjct: 129 AVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQ 188
Query: 1182 AKIPGLKRKAE 1192
AKIPGLKRKAE
Sbjct: 189 AKIPGLKRKAE 199
>gi|10863935 reticulon 1 isoform A [Homo sapiens]
Length = 776
Score = 271 bits (692), Expect = 4e-72
Identities = 219/655 (33%), Positives = 322/655 (49%), Gaps = 83/655 (12%)
Query: 602 ESEATPSPVLPDI--VMEAPLNSA------VPSAGASVIQPSSSPLE---ASSVNY---- 646
E TP P LPD+ + L S+ P+ V + + PL+ A + Y
Sbjct: 141 EELGTPGPSLPDVPGIESRGLFSSDSGIEMTPAESTEVNKILADPLDQMKAEAYKYIDIT 200
Query: 647 --ESIKHEPENPPPYEEA--------MSVSLKKVSGIKEEIKEPENINAAL-------QE 689
E +KH+ ++ P E+ +S+K G++E K P + + +
Sbjct: 201 RPEEVKHQEQHHPELEDKDLDFKNKDTDISIKP-EGVREPDK-PAPVEGKIIKDHLLEES 258
Query: 690 TEAPYISIACDLIKETKLSAEPAPDFS------DYSEMAKVEQPVPDHSELVEDSSPDSE 743
T APYI DL +E + + + + S ++ P+ ++ SPD+
Sbjct: 259 TFAPYID---DLSEEQRRAPQITTPVKITLTEIEPSVETTTQEKTPEKQDICLKPSPDTV 315
Query: 744 PVDLFS---DDSIPDVPQKQDETVMLVKESLTETSFESMIEYENKEKLSALPPEGGKPYL 800
P S DDS + T ES + S E ++A+ G Y
Sbjct: 316 PTVTVSEPEDDSPGSITPPSSGTEPSAAESQGKGSISE------DELITAIKEAKGLSYE 369
Query: 801 ESFKLSLDNTKDT-LLPD--EVSTLSKKEKIPLQMEELSTAVYSNDDLF--ISKEAQIRE 855
+ +N + L D EV S IP ++ +++ S D +S++ E
Sbjct: 370 TA-----ENPRPVGQLADRPEVKARSGPPTIPSPLDHEASSAESGDSEIELVSEDPMAAE 424
Query: 856 TETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEIANAPDGAGSLPCTEL 915
S + P +S + +S L RE + E+ + I + + S +
Sbjct: 425 DALPSGYVSFGHVGGPPPSPASPSIQYSIL-REEREAELDSELIIESCDASSASEESPKR 483
Query: 916 PHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPD--VSALATQAEIESIVKPKVL 973
D ++P + I A S+ L P + +T+ + + P
Sbjct: 484 EQDSP--PMKPSALDAIREETGVRAEERAPSRRGLAEPGSFLDYPSTEPQPGPELPPGDG 541
Query: 974 VKEAEKKL----PSDTEKEDRSPSAIFSAE------------LSKTSVVDLLYWRDIKKT 1017
E E + P + ++SP+A L+K +DLLYWRDIK+T
Sbjct: 542 ALEPETPMLPRKPEEDSSSNQSPAATKGPGPLGPGAPPPLLFLNKQKAIDLLYWRDIKQT 601
Query: 1018 GVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYL 1077
G+VFG+ L LL SLT FS+VSV AY+ALA LS TISFRIYK V+QA+QK+DEGHPF+AYL
Sbjct: 602 GIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDEGHPFKAYL 661
Query: 1078 ESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNG 1137
E E+ +S+E +QKY++ +VN T+KELRRLFLV DLVDSLKFAVLMW+ TYVGALFNG
Sbjct: 662 ELEITLSQEQIQKYTDCLQFYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNG 721
Query: 1138 LTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE 1192
LTLL++A++S+F++PV+Y +HQAQID YLGL ++ +AKIQAKIPG KR AE
Sbjct: 722 LTLLLMAVVSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAKIQAKIPGAKRHAE 776
Score = 41.2 bits (95), Expect = 0.006
Identities = 69/328 (21%), Positives = 127/328 (38%), Gaps = 32/328 (9%)
Query: 22 AFKYQFVREPEDEEEEEEEEEEDEDEDLE---ELEVLERKPAAGLSAAPVPTAPAAGAPL 78
A+KY + PE+ + +E+ E ED+DL+ + + KP P AP G +
Sbjct: 193 AYKYIDITRPEEVKHQEQHHPELEDKDLDFKNKDTDISIKPEG--VREPDKPAPVEGKII 250
Query: 79 MDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDE 138
D + AP +R+ +PV T+ P S + K PE +
Sbjct: 251 KDHLLEESTFAPY----IDDLSEEQRRAPQITTPVKITLTEIEP-SVETTTQEKTPEKQD 305
Query: 139 PPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEP 198
+P P +V+ +P + P + + P+A + +G ++ L ++
Sbjct: 306 ICLKPSPDTVPTVTVSEPEDDSPGSITPPSSGTEPSAAESQGKGSISEDELITAIKEAKG 365
Query: 199 VIRSSAENM----DLKEQPGNTISAGQEDFPSVLLETAAS---------LPSLSPLSAAS 245
+ +AEN L ++P +G PS L A+S L S P++A
Sbjct: 366 LSYETAENPRPVGQLADRPEVKARSGPPTIPSPLDHEASSAESGDSEIELVSEDPMAAED 425
Query: 246 FKEHEYL--GNLS--TVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMG 301
Y+ G++ P ++Q ++ +E ++ ++ D + SE
Sbjct: 426 ALPSGYVSFGHVGGPPPSPASPSIQYSILREEREAELDSELIIESCDASSASEESPKREQ 485
Query: 302 SSFSVSPKAESAVIVANPREEIIVKNKD 329
S + P A A+ REE V+ ++
Sbjct: 486 DSPPMKPSALDAI-----REETGVRAEE 508
Score = 34.3 bits (77), Expect = 0.73
Identities = 80/371 (21%), Positives = 131/371 (35%), Gaps = 84/371 (22%)
Query: 435 EKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATES--------IATNIFPLLGDP 486
+KD + N DT PEG+++ P PA E + P + D
Sbjct: 217 DKDLDFKNKDTDISIKPEGVRE---------PDKPAPVEGKIIKDHLLEESTFAPYIDDL 267
Query: 487 TSENK-----TDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTEE 541
+ E + T KI + + E T KT + + S D V T +++ ++
Sbjct: 268 SEEQRRAPQITTPVKITLTEIEPSVETTTQEKTPEKQDICLKPS-PDTVPTVTVSEPEDD 326
Query: 542 VVANM---PEGLTPDLVQEACESELNE---VTGTK----IAYETKMD------LVQTSEV 585
++ G P + + ++E +T K ++YET + L EV
Sbjct: 327 SPGSITPPSSGTEPSAAESQGKGSISEDELITAIKEAKGLSYETAENPRPVGQLADRPEV 386
Query: 586 MQESLYPAAQLCPSFEESEATPSPVLPDIVMEAPL--NSAVPSAGAS---VIQPSSSP-- 638
S P E S A ++V E P+ A+PS S V P SP
Sbjct: 387 KARSGPPTIPSPLDHEASSAESGDSEIELVSEDPMAAEDALPSGYVSFGHVGGPPPSPAS 446
Query: 639 ------------------------LEASSVNYESIKHEPENPPPYEEAMSVSLKKVSGIK 674
+ASS + ES K E ++PP A+ ++++ +G++
Sbjct: 447 PSIQYSILREEREAELDSELIIESCDASSASEESPKREQDSPPMKPSALD-AIREETGVR 505
Query: 675 EEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKVEQP-VPDHSE 733
E + P A + Y S +P P+ + E P +P E
Sbjct: 506 AEERAPSRRGLAEPGSFLDYPS----------TEPQPGPELPPGDGALEPETPMLPRKPE 555
Query: 734 LVEDSSPDSEP 744
EDSS + P
Sbjct: 556 --EDSSSNQSP 564
Score = 32.0 bits (71), Expect = 3.6
Identities = 42/158 (26%), Positives = 56/158 (35%), Gaps = 22/158 (13%)
Query: 16 PPRP-QPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPV-PTAPA 73
PP P P+ +Y +RE E E E + E E + E P + P+ P+A
Sbjct: 441 PPSPASPSIQYSILRE----EREAELDSELIIESCDASSASEESPKREQDSPPMKPSALD 496
Query: 74 AGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKL 133
A + P+ RG A P + PS +P P P L
Sbjct: 497 AIREETGVRAEERAPSRRG---LAEPGSFLDYPSTEPQPGPELPPGDGAL---------- 543
Query: 134 PEDDEPPARPPPPPPASVSPQAEPVWTPPAP-APAAPP 170
+ E P P P S S Q+ P P P APP
Sbjct: 544 --EPETPMLPRKPEEDSSSNQSPAATKGPGPLGPGAPP 579
>gi|45827778 reticulon 1 isoform B [Homo sapiens]
Length = 356
Score = 270 bits (691), Expect = 5e-72
Identities = 130/193 (67%), Positives = 162/193 (83%)
Query: 1000 LSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKG 1059
L+K +DLLYWRDIK+TG+VFG+ L LL SLT FS+VSV AY+ALA LS TISFRIYK
Sbjct: 164 LNKQKAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKS 223
Query: 1060 VIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSL 1119
V+QA+QK+DEGHPF+AYLE E+ +S+E +QKY++ +VN T+KELRRLFLV DLVDSL
Sbjct: 224 VLQAVQKTDEGHPFKAYLELEITLSQEQIQKYTDCLQFYVNSTLKELRRLFLVQDLVDSL 283
Query: 1120 KFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAK 1179
KFAVLMW+ TYVGALFNGLTLL++A++S+F++PV+Y +HQAQID YLGL ++ +AK
Sbjct: 284 KFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAK 343
Query: 1180 IQAKIPGLKRKAE 1192
IQAKIPG KR AE
Sbjct: 344 IQAKIPGAKRHAE 356
Score = 32.0 bits (71), Expect = 3.6
Identities = 42/158 (26%), Positives = 56/158 (35%), Gaps = 22/158 (13%)
Query: 16 PPRP-QPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPV-PTAPA 73
PP P P+ +Y +RE E E E + E E + E P + P+ P+A
Sbjct: 21 PPSPASPSIQYSILRE----EREAELDSELIIESCDASSASEESPKREQDSPPMKPSALD 76
Query: 74 AGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKL 133
A + P+ RG A P + PS +P P P L
Sbjct: 77 AIREETGVRAEERAPSRRG---LAEPGSFLDYPSTEPQPGPELPPGDGAL---------- 123
Query: 134 PEDDEPPARPPPPPPASVSPQAEPVWTPPAP-APAAPP 170
+ E P P P S S Q+ P P P APP
Sbjct: 124 --EPETPMLPRKPEEDSSSNQSPAATKGPGPLGPGAPP 159
>gi|45827776 reticulon 1 isoform C [Homo sapiens]
Length = 208
Score = 269 bits (688), Expect = 1e-71
Identities = 129/191 (67%), Positives = 161/191 (84%)
Query: 1002 KTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVI 1061
K+ +DLLYWRDIK+TG+VFG+ L LL SLT FS+VSV AY+ALA LS TISFRIYK V+
Sbjct: 18 KSQAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVL 77
Query: 1062 QAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKF 1121
QA+QK+DEGHPF+AYLE E+ +S+E +QKY++ +VN T+KELRRLFLV DLVDSLKF
Sbjct: 78 QAVQKTDEGHPFKAYLELEITLSQEQIQKYTDCLQFYVNSTLKELRRLFLVQDLVDSLKF 137
Query: 1122 AVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQ 1181
AVLMW+ TYVGALFNGLTLL++A++S+F++PV+Y +HQAQID YLGL ++ +AKIQ
Sbjct: 138 AVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAKIQ 197
Query: 1182 AKIPGLKRKAE 1192
AKIPG KR AE
Sbjct: 198 AKIPGAKRHAE 208
>gi|41393608 reticulon 3 isoform b [Homo sapiens]
Length = 1013
Score = 257 bits (656), Expect = 5e-68
Identities = 276/1056 (26%), Positives = 461/1056 (43%), Gaps = 149/1056 (14%)
Query: 213 PGNTISAGQEDFPSVLLETAASLPSLSPLS---AASFKEHEYLGNLS-TVLPTEGTLQEN 268
PG + G + S E +SL S P S +SF + N T+L E + +
Sbjct: 31 PGACPALGTKSCSSSCAEGLSSLCSDEPSSEIMTSSFLSSSEIHNTGLTILHGE---KSH 87
Query: 269 VSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVANPREEIIVKNK 328
V + ++++ K L DL + ++E + G+S +VS + S + I +
Sbjct: 88 VLGSQPILAKEGKDHL---DLLDMKKMEKPQ-GTSNNVSDSSVSLAAGVHCDRPSIPASF 143
Query: 329 DEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAKDSFNEKRVAVEAPMREEYADFK 388
E +S I ++++ K K VSS +AK + + ++ ++
Sbjct: 144 PEHPAFLSKKIGQVEEQID----KETKNPNGVSSREAKTALDADDRFTLLTAQKPPTEYS 199
Query: 389 PFERVW--EVKDSKEDSDMLAAGGKIESNLESKVDK----KCFADSLEQTNHE------- 435
E ++ + SK D + ES E +DK K F DS +++ +
Sbjct: 200 KVEGIYTYSLSPSKVSGDDVIEKDSPESPFEVIIDKAAFDKEFKDSYKESTDDFGSWSVH 259
Query: 436 KDSESSND-----DTSFPSTPE--------GIKDRSGAYITCA---------PFNPAATE 473
D ESS D D FP + + R ++ A + E
Sbjct: 260 TDKESSEDISETNDKLFPLRNKEAGRYPMSALLSRQFSHTNAALEEVSRCVNDMHNFTNE 319
Query: 474 SIATNIFPLLGDPTSEN-----KTDEKKIEEKKAQI-VTEKNTSTKTSNPFLVAAQDSET 527
+ ++ P + T ++ KT + E ++I V TST P V + D T
Sbjct: 320 ILTWDLVPQVKQQTDKSSDCITKTTGLDMSEYNSEIPVVNLKTSTHQKTP--VCSIDGST 377
Query: 528 DYV-TTDNLTKVT---EEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTS 583
+T + + + E + P PD + E + V G ++ +
Sbjct: 378 PITKSTGDWAEASLQQENAITGKP---VPDSLNSTKEFSIKGVQG---------NMQKQD 425
Query: 584 EVMQESLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLE--- 640
+ + E + C S AT VLPD ++ ++ + G SS +
Sbjct: 426 DTLAELPGSPPEKCDSLGSGVATVKVVLPDDHLKDEMDWQSSALGEITEADSSGESDDTV 485
Query: 641 ----ASSVNYESIKHEPENPPPYEEAMSVS----LKKVSGIKEEIKEPENINAALQETE- 691
+ ++E+ K + E P A+ + +K++ + E K +N + ++E
Sbjct: 486 IEDITADTSFENNKIQAEKPVSIPSAVVKTGEREIKEIPSCEREEKTSKNFEELVSDSEL 545
Query: 692 ----------APYISIACDLIKETKLSAEPAPDFSDYSEMAKVEQPVPDHSELVEDSSPD 741
+P AC + +T +S E D SE+A + ++ +L SP+
Sbjct: 546 HQDQPDILGRSPASEAACSKVPDTNVSLE------DVSEVAPEKPITTENPKLPSTVSPN 599
Query: 742 SEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMIEYENKEKLSALPPEGGKPYLE 801
+F++ + T ESL + + + + ++ ++A K ++
Sbjct: 600 -----VFNETEF-----SLNVTTSAYLESLHGKNVKHIDDSSPEDLIAAFTETRDKGIVD 649
Query: 802 S----FKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVYSNDDLFISKEAQIRETE 857
S FK + D V L + E +++++ + YS Q +ET
Sbjct: 650 SERNAFKAISEKMTDFKTTPPVEVLHENESGGSEIKDIGSK-YSE---------QSKET- 698
Query: 858 TFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEIANAPDGAGSLPCTELPH 917
+ S P+ + FPT + + L E L + E+ T
Sbjct: 699 --NGSEPLGV---FPT----QGTPVASLDLEQEQLTIKALKELGERQVEKS----TSAQR 745
Query: 918 DLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALATQAEIESIVKPKVLVKEA 977
D L + EE + + F+ +L +V +++ KP + +
Sbjct: 746 DAELPS-----EEVLKQTFTFAPESWPQRSYDILERNVK---NGSDLGISQKPITIRETT 797
Query: 978 EKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIV 1037
S K + + + L+ SV DL++WRD+KKTG VFG +L +LLSL FS++
Sbjct: 798 RVDAVSSLSKTELVKKHVLARLLTDFSVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVI 857
Query: 1038 SVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALG 1097
SV +Y+ LALLSVTISFRIYK VIQA+QKS+EGHPF+AYL+ ++ +S E Y N+A+
Sbjct: 858 SVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMV 917
Query: 1098 HVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYER 1157
H+N +K + RLFLV+DLVDSLK AV MW+ TYVGA+FNG+TLLILA + +FSVP++YE+
Sbjct: 918 HINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEK 977
Query: 1158 HQAQIDHYLGLANKNVKDAMAKIQAKIPGL-KRKAE 1192
++ QIDHY+G+A K + KIQAK+PG+ K+KAE
Sbjct: 978 YKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE 1013
>gi|5174655 reticulon 3 isoform a [Homo sapiens]
Length = 236
Score = 246 bits (627), Expect = 1e-64
Identities = 120/217 (55%), Positives = 161/217 (74%), Gaps = 1/217 (0%)
Query: 977 AEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSI 1036
AE P P+ + S +V DL++WRD+KKTG VFG +L +LLSL FS+
Sbjct: 20 AEPSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSV 79
Query: 1037 VSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSAL 1096
+SV +Y+ LALLSVTISFRIYK VIQA+QKS+EGHPF+AYL+ ++ +S E Y N+A+
Sbjct: 80 ISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAM 139
Query: 1097 GHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYE 1156
H+N +K + RLFLV+DLVDSLK AV MW+ TYVGA+FNG+TLLILA + +FSVP++YE
Sbjct: 140 VHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYE 199
Query: 1157 RHQAQIDHYLGLANKNVKDAMAKIQAKIPGL-KRKAE 1192
+++ QIDHY+G+A K + KIQAK+PG+ K+KAE
Sbjct: 200 KYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE 236
>gi|41393604 reticulon 3 isoform c [Homo sapiens]
Length = 255
Score = 245 bits (626), Expect = 2e-64
Identities = 116/193 (60%), Positives = 155/193 (80%), Gaps = 1/193 (0%)
Query: 1001 SKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGV 1060
S + V DL++WRD+KKTG VFG +L +LLSL FS++SV +Y+ LALLSVTISFRIYK V
Sbjct: 63 STSQVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSV 122
Query: 1061 IQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLK 1120
IQA+QKS+EGHPF+AYL+ ++ +S E Y N+A+ H+N +K + RLFLV+DLVDSLK
Sbjct: 123 IQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLK 182
Query: 1121 FAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKI 1180
AV MW+ TYVGA+FNG+TLLILA + +FSVP++YE+++ QIDHY+G+A K + KI
Sbjct: 183 LAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKI 242
Query: 1181 QAKIPGL-KRKAE 1192
QAK+PG+ K+KAE
Sbjct: 243 QAKLPGIAKKKAE 255
>gi|41393606 reticulon 3 isoform d [Homo sapiens]
Length = 241
Score = 209 bits (532), Expect = 1e-53
Identities = 101/183 (55%), Positives = 136/183 (74%)
Query: 977 AEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSI 1036
AE P P+ + S +V DL++WRD+KKTG VFG +L +LLSL FS+
Sbjct: 20 AEPSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSV 79
Query: 1037 VSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSAL 1096
+SV +Y+ LALLSVTISFRIYK VIQA+QKS+EGHPF+AYL+ ++ +S E Y N+A+
Sbjct: 80 ISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAM 139
Query: 1097 GHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYE 1156
H+N +K + RLFLV+DLVDSLK AV MW+ TYVGA+FNG+TLLILA + +FSVP++YE
Sbjct: 140 VHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYE 199
Query: 1157 RHQ 1159
+++
Sbjct: 200 KYK 202
>gi|5032055 reticulon 2 isoform A [Homo sapiens]
Length = 545
Score = 188 bits (478), Expect = 2e-47
Identities = 94/195 (48%), Positives = 134/195 (68%), Gaps = 1/195 (0%)
Query: 992 PSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVT 1051
PS A++ + V DLLYW+D + +GVVF + LL L FSIVSV A++AL LL T
Sbjct: 333 PSLSLGADMG-SKVADLLYWKDTRTSGVVFTGLMVSLLCLLHFSIVSVAAHLALLLLCGT 391
Query: 1052 ISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFL 1111
IS R+Y+ V+QA+ + D +PF+AYL+ ++ ++ E ++ S+ V +LR FL
Sbjct: 392 ISLRVYRKVLQAVHRGDGANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRHFFL 451
Query: 1112 VDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANK 1171
V+DLVDSLK A+L ++ T+VGA+FNGLTLLIL +I LF++P++Y +HQAQID Y+GL
Sbjct: 452 VEDLVDSLKLALLFYILTFVGAIFNGLTLLILGVIGLFTIPLLYRQHQAQIDQYVGLVTN 511
Query: 1172 NVKDAMAKIQAKIPG 1186
+ AKI+AKIPG
Sbjct: 512 QLSHIKAKIRAKIPG 526
>gi|46255005 reticulon 2 isoform B [Homo sapiens]
Length = 472
Score = 187 bits (475), Expect = 5e-47
Identities = 100/224 (44%), Positives = 144/224 (64%), Gaps = 8/224 (3%)
Query: 970 PKVLVKEAEKKLPSDTEKE-------DRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFG 1022
P+ + E E+K E+E D + F+ E + V DLLYW+D + +GVVF
Sbjct: 231 PEEPLLEEEEKQWGPLEREPVRGQCLDSTDQLEFTVE-PRLLVADLLYWKDTRTSGVVFT 289
Query: 1023 ASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVA 1082
+ LL L FSIVSV A++AL LL TIS R+Y+ V+QA+ + D +PF+AYL+ ++
Sbjct: 290 GLMVSLLCLLHFSIVSVAAHLALLLLCGTISLRVYRKVLQAVHRGDGANPFQAYLDVDLT 349
Query: 1083 ISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLI 1142
++ E ++ S+ V +LR FLV+DLVDSLK A+L ++ T+VGA+FNGLTLLI
Sbjct: 350 LTREQTERLSHQITSRVVSAATQLRHFFLVEDLVDSLKLALLFYILTFVGAIFNGLTLLI 409
Query: 1143 LALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPG 1186
L +I LF++P++Y +HQAQID Y+GL + AKI+AKIPG
Sbjct: 410 LGVIGLFTIPLLYRQHQAQIDQYVGLVTNQLSHIKAKIRAKIPG 453
>gi|46255007 reticulon 2 isoform C [Homo sapiens]
Length = 205
Score = 187 bits (474), Expect = 7e-47
Identities = 91/184 (49%), Positives = 129/184 (70%)
Query: 1003 TSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQ 1062
+ V DLLYW+D + +GVVF + LL L FSIVSV A++AL LL TIS R+Y+ V+Q
Sbjct: 3 SKVADLLYWKDTRTSGVVFTGLMVSLLCLLHFSIVSVAAHLALLLLCGTISLRVYRKVLQ 62
Query: 1063 AIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFA 1122
A+ + D +PF+AYL+ ++ ++ E ++ S+ V +LR FLV+DLVDSLK A
Sbjct: 63 AVHRGDGANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRHFFLVEDLVDSLKLA 122
Query: 1123 VLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQA 1182
+L ++ T+VGA+FNGLTLLIL +I LF++P++Y +HQAQID Y+GL + AKI+A
Sbjct: 123 LLFYILTFVGAIFNGLTLLILGVIGLFTIPLLYRQHQAQIDQYVGLVTNQLSHIKAKIRA 182
Query: 1183 KIPG 1186
KIPG
Sbjct: 183 KIPG 186
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 77.8 bits (190), Expect = 6e-14
Identities = 59/158 (37%), Positives = 68/158 (43%), Gaps = 26/158 (16%)
Query: 38 EEEEEEDEDEDLEE-----LEVLERKPAAGLSAAPVPT----APAA---------GAPLM 79
+EE+ ++ DL+E + L+ P AG P APAA G P
Sbjct: 1383 DEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSA 1442
Query: 80 DFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEP 139
+ PP P PP AP QP P P PSP A +PS P P
Sbjct: 1443 NSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPP----P 1498
Query: 140 PARPPPPPPASVSPQAEPVWTPPAPAP-AAPPSTPAAP 176
P PPPPPPA SP P PPA AP AAPP PAAP
Sbjct: 1499 PPLPPPPPPAMPSPPPPP---PPAAAPLAAPPEEPAAP 1533
Score = 43.1 bits (100), Expect = 0.002
Identities = 43/141 (30%), Positives = 55/141 (39%), Gaps = 20/141 (14%)
Query: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPL-----PAAPPVAPERQPSWDPSPVSS 115
A L +P P P A + P P G L P P V P P PS V S
Sbjct: 758 AFLQKSPPPPPPTAQS---------TQPTPHGLLLEAGGPDLPLVLPPPPPQLLPS-VLS 807
Query: 116 TVPAPSPLSAAA----VSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPS 171
P+PSP ++ + P+ +PP PPPPPP + Q E PAAP
Sbjct: 808 HAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPP-PMPLQLEAHLRSHGLEPAAPSP 866
Query: 172 TPAAPKRRGSSGSVDETLFAL 192
+ G++ E L AL
Sbjct: 867 RLRPEESLDPPGAMQELLGAL 887
Score = 42.0 bits (97), Expect = 0.003
Identities = 35/117 (29%), Positives = 46/117 (39%), Gaps = 5/117 (4%)
Query: 63 LSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAP--PVAPERQPSWDPSPVSSTVPAP 120
L + PT P++ G + PA GP P P P+ P P + A
Sbjct: 191 LKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLAS 250
Query: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPV---WTPPAPAPAAPPSTPA 174
S +AAA S + A P PPPP P+ + V + PA A PP PA
Sbjct: 251 SSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPA 307
Score = 37.7 bits (86), Expect = 0.066
Identities = 31/126 (24%), Positives = 45/126 (35%), Gaps = 17/126 (13%)
Query: 118 PAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPK 177
P P S A +P PP + P PPP +P+ PP P P AP+
Sbjct: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPE 1730
Query: 178 RRGSSGSVDETLFALPAASEPVIR-SSAENMDLKEQP--GNTISAGQEDFPSVLLETAAS 234
+ P+ PV + E + E+P G ++G++ P L T
Sbjct: 1731 K--------------PSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQP 1776
Query: 235 LPSLSP 240
S P
Sbjct: 1777 ATSRLP 1782
Score = 35.0 bits (79), Expect = 0.43
Identities = 38/147 (25%), Positives = 52/147 (35%), Gaps = 16/147 (10%)
Query: 62 GLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPS 121
G S P +A +A FG+ P P PP +P P V P+ +
Sbjct: 138 GSSTFPSSSALSAYQHPASFGSRPFP-VPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQA 196
Query: 122 PL-----------SAAAVSPSKLPEDDEPPARP----PPPPPASVSPQAEPVWTPPAPAP 166
P + P+ L PP RP PPPPP + Q + + A A
Sbjct: 197 PTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAA 256
Query: 167 AAPPSTPAAPKRRGSSGSVDETLFALP 193
AA S+P G++ ALP
Sbjct: 257 AAEQSSPQLYNFSGAAPGPPPPERALP 283
Score = 35.0 bits (79), Expect = 0.43
Identities = 42/178 (23%), Positives = 60/178 (33%), Gaps = 27/178 (15%)
Query: 87 PPAPRGPLPAAP------PVAPERQPSWDP-SPVSSTVPAPSPLSAAAVSPSKL------ 133
P A GP P P P P R P +P P P + V+ L
Sbjct: 974 PKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSG 1033
Query: 134 PEDDEPPARPPPPPPASVSPQ-----AEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDET 188
P PP PPPPPP + + + P++ P S+ +RR +
Sbjct: 1034 PHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKK 1093
Query: 189 LFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASF 246
L+A E + D++ P L+ + S P+LSPL F
Sbjct: 1094 LYAQEYEFEADEDKADVPADIRLNPRRLPD---------LVSSCRSRPALSPLGDIDF 1142
Score = 34.3 bits (77), Expect = 0.73
Identities = 37/138 (26%), Positives = 51/138 (36%), Gaps = 20/138 (14%)
Query: 122 PLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGS 181
PL A ++P P P + PP P + PQ P P P+ A + S
Sbjct: 1297 PLYQAGLTPPLSP----PKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAES 1352
Query: 182 SG--------------SVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSV 227
G + L LP+ S S A+N DL+E + ISA D P +
Sbjct: 1353 EGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISA--LDDPPL 1410
Query: 228 LLETAASLPSLSPLSAAS 245
S P PL+ A+
Sbjct: 1411 AGPKDTSTPDGPPLAPAA 1428
Score = 32.3 bits (72), Expect = 2.8
Identities = 34/125 (27%), Positives = 43/125 (34%), Gaps = 23/125 (18%)
Query: 66 APVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPS-PLS 124
+P P+A G L++ PA R P PP P P P P+ S L
Sbjct: 811 SPSPSASKVGVHLLE-------PATRDGAPQPPPPPPPPPP---PMPLQLEAHLRSHGLE 860
Query: 125 AAAVSPSKLPEDD-EPPAR-----------PPPPPPASVSPQAEPVWTPPAPAPAAPPST 172
AA SP PE+ +PP PP P V P P + P
Sbjct: 861 PAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQG 920
Query: 173 PAAPK 177
AP+
Sbjct: 921 TKAPR 925
Score = 32.3 bits (72), Expect = 2.8
Identities = 43/189 (22%), Positives = 63/189 (33%), Gaps = 20/189 (10%)
Query: 52 LEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDP- 110
+ V RKP PVP + A P P+ P P P PE+ S P
Sbjct: 1659 VRVCARKP---WHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPP 1715
Query: 111 --SPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAA 168
+P ++ P+P + + P + ++ E R P + P
Sbjct: 1716 EQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQT-RPERSLATG 1774
Query: 169 PPSTPAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVL 228
P+T PK R + + A P R LKE GN + G S
Sbjct: 1775 QPATSRLPKARPTK---------VKAEPPPKKRKKW----LKEAGGNATAGGGPPGSSSD 1821
Query: 229 LETAASLPS 237
E++ PS
Sbjct: 1822 SESSPGAPS 1830
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 67.8 bits (164), Expect = 6e-11
Identities = 217/1048 (20%), Positives = 378/1048 (36%), Gaps = 124/1048 (11%)
Query: 32 EDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAP- 90
E+E EEEEE E E E +EE E + + + V PA + P P
Sbjct: 9511 EEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPA 9570
Query: 91 --RGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPA---RPPP 145
P PA P AP++ VPAP P V P K+PE+ + P + PP
Sbjct: 9571 KIEEPPPAKVPEAPKKIVP------EKKVPAPVP-KKEKVPPPKVPEEPKKPVPEKKVPP 9623
Query: 146 -------PPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEP 198
P PA V+ + + T A A PK R +E A+P E
Sbjct: 9624 KVIKMEEPLPAKVTERHMQI-TQEEKVLVAVTKKEAPPKARVP----EEPKRAVP--EEK 9676
Query: 199 VIRSSAENMDLKEQPGNTISAGQEDF---PSVLLETAASLPS-LSPLSAASFKEHEY-LG 253
V++ + +E+P ++ ++ V +E P + ++ KE Y L
Sbjct: 9677 VLKLKPKR---EEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLE 9733
Query: 254 NLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAESA 313
+ + E +E KE E T D+ E+ E EY + E
Sbjct: 9734 EEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQ-YEEYEEREYERYEEHEEYITEPEKP 9792
Query: 314 VIVAN-PREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAKDSFNEK 372
+ V P E + K K K++ + ++++P + K +K E+ K F EK
Sbjct: 9793 IPVKPVPEEPVPTKPKAPPAKVLKKAV--PEEKVPVPIPKKLKPPPPKVPEEPKKVFEEK 9850
Query: 373 -RVAVEAPMREEYAD------FKPFERVWEVKDSKEDSDMLAAGGKIESNLESKVDKKCF 425
R+++ +E+ + KP V E K ++ E E + ++ F
Sbjct: 9851 IRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAF 9910
Query: 426 ADSL----EQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIFP 481
+ + E+ E++ E +++ F T E + + P P E +
Sbjct: 9911 EEEVVTHVEEYLVEEEEEYIHEEEEF-ITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPK 9969
Query: 482 LLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFL-----------------VAAQD 524
P ++ KK EEK ++ +K P + V A
Sbjct: 9970 KKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPP 10029
Query: 525 SETDYVTTDNL-----------------TKVTEEVVANMPEGLTPDLVQEACESELNEVT 567
++ V + KV E +PE P V + E+ +V
Sbjct: 10030 AKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVP 10089
Query: 568 GTKIAYETKMDLVQTSEVM-QESLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAVPS 626
+ + L Q EV+ +E + P ++ P EE VLP+ P +P
Sbjct: 10090 KKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPP 10149
Query: 627 AGASVI-QPSSSPLEASSVNYESIKHE-----PENPPPYEEAMSVSLKKVSGIKEEIKEP 680
V + P E V E + E P P E V+ KKV K+E P
Sbjct: 10150 EEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPP 10209
Query: 681 ENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKVEQPV-PDHSELVEDSS 739
+ ++ E I + KE ++ + + +++ E P P E VE+ +
Sbjct: 10210 AKVPEVPKKVEEKRIILP----KEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVA 10265
Query: 740 PDSEPVDLFSDDSIPD----VPQKQDETVMLVKESLTETSFESMIEYENKEKLSALPPEG 795
P P + ++P+ VP+K + V + + E + + KE A PE
Sbjct: 10266 PPRVPEVI--KKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVP--VPVQKKEAPPAKVPEV 10321
Query: 796 GKPYLESFKL-----SLDNTKD-TLLPDEVSTLSKKEKIPLQMEELSTAVYSNDDLFISK 849
K E L ++ K T+L ++VS ++E + + EL ++ I +
Sbjct: 10322 PKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEE--IPE 10379
Query: 850 EAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEI-----ANAP 904
E + E E + + ++EF L + + ++ + + +EV E+ AP
Sbjct: 10380 EEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAP 10439
Query: 905 DGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALATQAEI 964
+ +P + P+ E + K + + +P + T ++
Sbjct: 10440 PKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKK--IVVEEKVRVPEEPRVPPT--KV 10495
Query: 965 ESIVKPKVLVKEAEKKLPSDTEKEDRSP 992
++ PK +V EKK+P K+ +P
Sbjct: 10496 PEVLPPKEVV--PEKKVPVPPAKKPEAP 10521
Score = 64.7 bits (156), Expect = 5e-10
Identities = 151/693 (21%), Positives = 235/693 (33%), Gaps = 118/693 (17%)
Query: 17 PRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTA--PAA 74
PR +P K V + EE+ EE + EVL K PVP A P A
Sbjct: 10461 PRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEA 10520
Query: 75 GAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP-----------SPL 123
P + V P + P+P PP PE P+ P + VP SP
Sbjct: 10521 PPPKVPEAPKEVVPEKKVPVP--PPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPP 10578
Query: 124 SAAAVSPSKLPEDDEPPARPPPPP----------PASVSPQAEPVWTPPAPAPAAPPS-T 172
+P ++ + + PA PP P P V P+ + V PP P PP+
Sbjct: 10579 PEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKK-VPVPPPKKPEVPPTKV 10637
Query: 173 PAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETA 232
P PK V E + P + P + E + L+E P + + P
Sbjct: 10638 PEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVV-----EEPEPAAPPQ 10692
Query: 233 ASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEF 292
++P P+ K + + P + V E KEV + K L+
Sbjct: 10693 VTVPPKKPVPEK--KAPAVVAKKPELPPVK------VPEVPKEVVPEKKVPLV------- 10737
Query: 293 SELEYSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTK 352
P+A A + P+E + EK V+ + + E+P A
Sbjct: 10738 -----------VPKKPEAPPAKVPEVPKEVV-------PEKKVA---VPKKPEVPPAKVP 10776
Query: 353 LVKEDEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKI 412
V + V+ E++ AV P R E + +E E+ +E + +
Sbjct: 10777 EVPKKPVL----------EEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPV 10826
Query: 413 ESNLESKVDKKCFADSLEQTNHEKDSESSNDDTSFP---STPEGIKDRSGAYITCAPFNP 469
E +V + ++ EK + P PE + ++ P P
Sbjct: 10827 AEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPP 10886
Query: 470 A-ATESIATNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETD 528
A E + IF L P +KK+ EK V EK T P V + +
Sbjct: 10887 APPKEDVKEKIFQLKAIP-------KKKVPEKPQ--VPEKVELT----PLKVPGGEKKVR 10933
Query: 529 YVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQE 588
+ + + EEVV ++++ E E +V K+ K
Sbjct: 10934 KLLPERKPEPKEEVVLK-------SVLRKRPEEEEPKVEPKKLEKVKK------------ 10974
Query: 589 SLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYES 648
PA P + E P + + P + VP ++ P+ P ++
Sbjct: 10975 ---PAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKT 11031
Query: 649 IKHEPENPPPYEEAMSVSLKKVSGIKEEIKEPE 681
IK P P P A V++ V G K E K P+
Sbjct: 11032 IKPPPVEPEPTPIAAPVTV-PVVGKKAEAKAPK 11063
Score = 63.5 bits (153), Expect = 1e-09
Identities = 227/1132 (20%), Positives = 393/1132 (34%), Gaps = 240/1132 (21%)
Query: 28 VREPEDEEEEEEEEE-----EDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFG 82
V PE ++E EE+ E ++ L KPA APVP P
Sbjct: 9259 VTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPE-EVAPVPIPKKVEPPAPKVP 9317
Query: 83 NDFVPPAPRG----PLPAAPPVAPERQPSWDPSPV-SSTVPAPSPLSAAAVSPSKLPE-- 135
P P P+P P AP + P PV +P P A P+K+PE
Sbjct: 9318 EVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEA-PPAKVPEVQ 9376
Query: 136 ---------------DDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
++ PP P P V + +PV P PP PA PK+
Sbjct: 9377 KGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPP-PPKVPALPKK-- 9433
Query: 181 SSGSVDETLFALP---AASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPS 237
V E A+P A P R+ + E+ A ++ +V +
Sbjct: 9434 ---PVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEE--KRFVAEEKLSFAVPQRVEVTRHE 9488
Query: 238 LSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFS---E 294
+S S+ E E ++S E +E EV E+ + +++ L S E
Sbjct: 9489 VSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVE 9548
Query: 295 LEYSEMGS----SFSVSPKA---------------------ESAVIVANPREEIIVKNKD 329
E +E+ + PK E V P++E + K
Sbjct: 9549 AEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKV 9608
Query: 330 EEE-------KLVSNNILHNQQELPTALTK----LVKEDEVVSSEKAKDS---------- 368
EE K V ++ ++ LP +T+ + +E++V+ + K++
Sbjct: 9609 PEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEP 9668
Query: 369 -------------------------------FNEKRVAVEAPMREEYADFKPFERVWEVK 397
E++V++EAP RE +P + V ++
Sbjct: 9669 KRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREP----QPIKEVTIME 9724
Query: 398 DSKE----DSDMLAAGGKIESNLESKVDKKCFAD-----------SLEQTNHEKDSESSN 442
+ + + + ++ + E + D K F + E+ +E+ E
Sbjct: 9725 EKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEE 9784
Query: 443 DDTSFPSTPEGIKDRSGAYITCAPFNPAAT--------ESIATNIFPLLGDPTSENKTDE 494
T P P +K + P P A E + I L P + +
Sbjct: 9785 YITE-PEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEP 9843
Query: 495 KKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTEEVVA------NMPE 548
KK+ E+K +I K + + P A + V + V + VA +P+
Sbjct: 9844 KKVFEEKIRISITKREKEQVTEP--AAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPK 9901
Query: 549 GLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSE-VMQESLYPAAQLCPSFEESEATP 607
L P+ V A E E+ + E + + + E + +E + P + + P
Sbjct: 9902 ELEPEEV--AFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPV-----KVPEVP 9954
Query: 608 SPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYEEAMSVSL 667
+P+ P+ + A V + P E V + + E PPP + V
Sbjct: 9955 RKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPV----LIPKKEKPPP-AKVPEVPK 10009
Query: 668 KKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKVEQP 727
K V K + P+ + A A + + E K+ PAP KVE P
Sbjct: 10010 KPVPEEKVPVPVPKKVEAP----PAKVPEVPKKPVPEKKVPV-PAPK--------KVEAP 10056
Query: 728 VPDHSELVEDSSPDSE---PVDLFSDDSIPDVPQKQDET---VMLVKESLTETSFESMIE 781
E+ + P+ + PV + P VP+K++ V L +E E FE I
Sbjct: 10057 PAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEE--EVLFEEEIV 10114
Query: 782 YENK---EKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTA 838
E + E+ LP E + +LP+E L ++E+IP + EE
Sbjct: 10115 PEEEVLPEEEEVLPEE-----------------EEVLPEEEEVLPEEEEIPPEEEE---- 10153
Query: 839 VYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKS 898
V ++ +E + E E + P + + K +V+ K
Sbjct: 10154 VPPEEEYVPEEEEFVPEEEVLPEVKP-------KVPVPAPVPEIKK--------KVTEKK 10198
Query: 899 EIANAPDGAGSLPCTELPHDLSLKN-IQPKVEE--KISFSDDFSKNGSATSKVLLLPPDV 955
+ + A E+P + K I PK EE + +++ + + ++ PP +
Sbjct: 10199 VVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSI 10258
Query: 956 SALATQAEIESIVKPKV--LVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSV 1005
E+E + P+V ++K+A + P+ K+ +P A S ++ + V
Sbjct: 10259 E------EVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKV 10304
Score = 55.8 bits (133), Expect = 2e-07
Identities = 198/938 (21%), Positives = 320/938 (34%), Gaps = 172/938 (18%)
Query: 7 SPLVSSSDSPPRPQP---AFKYQFVREPED---EEEEEEEEEEDE--------------- 45
+P V + P +P AF+ + V E+ EEEEE EE+E
Sbjct: 9891 APPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKV 9950
Query: 46 --------DEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPA-----PRG 92
E+ + + V ++K A VP P P++ + PPA P+
Sbjct: 9951 PEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKK 10010
Query: 93 PLPA------------APPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPP 140
P+P APP P VPAP + A ++P+ P
Sbjct: 10011 PVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPE 10070
Query: 141 ARPPPPPPASVS--PQAEPVWTPPAPAPAAPPS----------TPAAPKRRGSSGSVDET 188
+ P P P V P P P P P A P P + E
Sbjct: 10071 EKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEE 10130
Query: 189 LFALPAASEPVIRSSAENMDLKEQ---PGNTISAGQEDF---PSVLLETAASLPSLSPLS 242
LP E + E + +E+ P +E+F VL E +P +P+
Sbjct: 10131 EEVLPEEEE--VLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVP 10188
Query: 243 AASFKEHEYLGNLSTVLP-TEGTLQENVSEASKEVSEKAKTL-----LIDRDLTEFSELE 296
K E V+P E V E K+V EK L ++ ++TE E E
Sbjct: 10189 EIKKKVTE----KKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEE 10244
Query: 297 YSEMGSSFSVSPKAESAVIVANPR-EEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVK 355
P E VA PR E+I K E V + + P ++K +
Sbjct: 10245 PISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKV----EAPPAKVSKKIP 10300
Query: 356 EDEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESN 415
E++V + K++ K V + E+ E V K + ++ + E
Sbjct: 10301 EEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVV 10360
Query: 416 LESKVDKKCFADSLEQTNHEK---DSESSNDDTSFPSTPEGIK----------------- 455
++ +++ + +E+ E+ + E ++ F E IK
Sbjct: 10361 VKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHR 10420
Query: 456 -----DRSGAYITCAPFNPAATESIATNIFPLLGDPTS--ENKTDEKKIEEKKAQIVTEK 508
+ + P P I+ I P PT K K+ E +IV E+
Sbjct: 10421 VIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEE 10480
Query: 509 NTSTKTSNPFLVAAQDSETDYVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEVTG 568
E V TKV E + P+ + P+ ++ E
Sbjct: 10481 KVRV------------PEEPRVPP---TKVPEVL---PPKEVVPEKKVPVPPAKKPEAPP 10522
Query: 569 TKIAYETKMDLVQTSEVMQESLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAVPSAG 628
K+ K EV+ E P P ++ E P+ V P++ A VP A
Sbjct: 10523 PKVPEAPK-------EVVPEKKVPV----PPPKKPEVPPTKV-PEVPKAAVPEKKVPEAI 10570
Query: 629 ASVIQPSSSPLEASSVNYESI--KHEPENPPPYEEAMSVSLKKVSGIKEEIKE-----PE 681
+P S P E E + K P PP E V + + KE + E P
Sbjct: 10571 PP--KPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAP--KEVVPEKKVPVPP 10626
Query: 682 NINAALQETEAPYISIACDLIKETKLSAEPAPD------FSDYSEMAKVEQPVPDHSELV 735
+ T+ P + K+ + P P+ F + E+A E P +E+V
Sbjct: 10627 PKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPP----AEVV 10682
Query: 736 EDSSPDSEPVDLFSDDSIP---DVPQKQDETVMLVKESLTETSF-ESMIEYENKEKLSAL 791
E+ P + P ++P VP+K+ V+ K L E E ++K+ +
Sbjct: 10683 EEPEPAAPP-----QVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLV 10737
Query: 792 PPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIP 829
P+ KP E+ + ++P++ + KK ++P
Sbjct: 10738 VPK--KP--EAPPAKVPEVPKEVVPEKKVAVPKKPEVP 10771
Score = 50.8 bits (120), Expect = 7e-06
Identities = 59/228 (25%), Positives = 86/228 (37%), Gaps = 29/228 (12%)
Query: 8 PLV--SSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSA 65
PLV ++PP P + V E + ++ E + ++ + VLE KPA
Sbjct: 10735 PLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAV---- 10790
Query: 66 APVPTAPAAGAP-LMDFGNDFVPPAPRGPLPAAP-PVAPERQPSWDPSPVSSTVPAPSPL 123
PVP + P + + + P P P PVA E +P VP P
Sbjct: 10791 -PVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPE---------VPPP--- 10837
Query: 124 SAAAVSPSKL-PEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSS 182
A P K+ PE P + P PP P+ E V P P PP PA PK
Sbjct: 10838 -AVPEEPKKIIPEKKVPVIKKPEAPPPK-EPEPEKVIEKPKLKPRPPPPPPAPPKE---- 10891
Query: 183 GSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLE 230
V E +F L A + + + + E + G++ +L E
Sbjct: 10892 -DVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPE 10938
Score = 50.4 bits (119), Expect = 1e-05
Identities = 93/415 (22%), Positives = 147/415 (35%), Gaps = 36/415 (8%)
Query: 24 KYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERK---PAAGLSAAPVPTAPAAGAPLMD 80
K F E+E E + E E++ V K P + P AP AP+
Sbjct: 9246 KMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPV-P 9304
Query: 81 FGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLP-----E 135
PPAP+ P PV E++P P + P + V K+P +
Sbjct: 9305 IPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKK 9364
Query: 136 DDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAA 195
+ PPA+ P V+ + + T +P PP+ P PK++ +P
Sbjct: 9365 KEAPPAKVPEVQKGVVTEEKITIVTQREESP--PPAVPEIPKKK------------VPEE 9410
Query: 196 SEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP----SLSPLSAASFKEHEY 251
+PV R E + P E+ +V + A P +S + K
Sbjct: 9411 RKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVA 9470
Query: 252 LGNLSTVLP--TEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPK 309
LS +P E T E +E SE+ + + I E E E + + V +
Sbjct: 9471 EEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEE 9530
Query: 310 AESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAKDSF 369
E V+ + II K + E V+ P K+ + E K
Sbjct: 9531 PEEYVV--EEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIV 9588
Query: 370 NEKRVAVEAPMREEYADFK-PFERVWEVKDSKEDSDMLAAGGKIESNLESKVDKK 423
EK+V P +E+ K P E V + K ++ K+E L +KV ++
Sbjct: 9589 PEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVI----KMEEPLPAKVTER 9639
Score = 48.9 bits (115), Expect = 3e-05
Identities = 143/718 (19%), Positives = 274/718 (38%), Gaps = 88/718 (12%)
Query: 308 PKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEKAKD 367
P + +I A E I V +K EE K+++ T ++ KE E V EK +
Sbjct: 9013 PPPPTTLIPAKAPEIIDVSSKAEEVKIMTI----------TRKKEVQKEKEAVY-EKKQA 9061
Query: 368 SFNEKRVAVEAPMREEYADFK------PFERVWEVKDSKEDSDMLAAGGKIESNLESKVD 421
EKRV +E+ E Y + + PFE+ + ++ ED + + K E + E + D
Sbjct: 9062 VHKEKRVFIES-FEEPYDELEVEPYTEPFEQPY-YEEPDEDYEEIKVEAKKEVHEEWEED 9119
Query: 422 KKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIFP 481
F + E E+ + ++ E ++R + + + + +
Sbjct: 9120 ---FEEGQEYYEREEGYDEGEEEWE-----EAYQEREVIQVQKEVYEESHERKVPAKVPE 9171
Query: 482 LLGDPTSE--NKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVT 539
P + K +KIE+ ++ EK TK + S+ + T V
Sbjct: 9172 KKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVP-------EVSKKIVPQKPSRTPVQ 9224
Query: 540 EEVV-ANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAA--QL 596
EEV+ +P T +V E ++ + T+ + VQ V +E ++ A ++
Sbjct: 9225 EEVIEVKVPAVHTKKMV--ISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRV 9282
Query: 597 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP 656
P + E P P+ V P+ V V + P+ K EP P
Sbjct: 9283 EPPPKVPELPEKPA-PEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAP 9341
Query: 657 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIA-CDLIKETKLSAEPAPDF 715
P E + + K+ E A + E + ++ ++ + + S PA
Sbjct: 9342 PKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPE 9401
Query: 716 SDYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKES---LT 772
++ + +PVP E V P V +P+ +K V + K++
Sbjct: 9402 IPKKKVPEERKPVPRKEEEV----PPPPKVPALPKKPVPE--EKVAVPVPVAKKAPPPRA 9455
Query: 773 ETSFESMIEYEN---KEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIP 829
E S ++++E + +EKLS P+ ++ T+ + +E + S++E
Sbjct: 9456 EVSKKTVVEEKRFVAEEKLSFAVPQ-----------RVEVTRHEVSAEEEWSYSEEE--- 9501
Query: 830 LQMEELSTAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREY 889
E +S +VY ++ +EA++ E E + +++E +IS + ++ E
Sbjct: 9502 ---EGVSISVYREEEREEEEEAEVTEYEVMEEPEEY-VVEEKLHIISKRVEAEPAEVTER 9557
Query: 890 TDLEVSHKSEI---------ANAPDGAGSL-PCTELPHDLSLKNI--QPKVEEKISFSDD 937
+ ++ K +I A P+ + P ++P + K PKV E+
Sbjct: 9558 QEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVP 9617
Query: 938 FSKNGSATSKVLLLPPDVSALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAI 995
K KV+ + + A T+ ++ + KVLV +K+ P + A+
Sbjct: 9618 EKK---VPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAV 9672
Score = 44.3 bits (103), Expect = 7e-04
Identities = 141/753 (18%), Positives = 266/753 (35%), Gaps = 144/753 (19%)
Query: 55 LERKPAAGLSAAPVPTAP-----AAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWD 109
+E+K A A + T AAG L +PP P+ P P +A + Q +
Sbjct: 221 IEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQ 280
Query: 110 PSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAP 169
SP S +PSP+ P P P SVSP A + +P
Sbjct: 281 QSP-SPIRHSPSPVRHVRA--------------PTPSPVRSVSPAAR-----ISTSPIRS 320
Query: 170 PSTPAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLL 229
+P ++ +S P E + SS+E E T++ +
Sbjct: 321 VRSPLLMRKTQASTVATGPEVPPPWKQEGYVASSSE----AEMRETTLTTSTQIRTEERW 376
Query: 230 ETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKA------KTL 283
E + +S A+ G ++V + E V+ +KEV + A T+
Sbjct: 377 EGRYGVQEQVTISGAA-------GAAASVSASASYAAEAVATGAKEVKQDADKSAAVATV 429
Query: 284 LIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVANPREE--------------IIVKNKD 329
+ D+ E S + + + + + + P +E ++ +K
Sbjct: 430 VAAVDMARVREPVISAVEQT---AQRTTTTAVHIQPAQEQVRKEAEKTAVTKVVVAADKA 486
Query: 330 EEEKLVSNN---ILHNQQELPTALTKLVKEDE-------VVSSEKAKDSFNEKRVAVEAP 379
+E++L S I Q+++ ++ KE E V+S+ KAK+ E R++ E
Sbjct: 487 KEQELKSRTKEVITTKQEQMHVTHEQIRKETEKTFVPKVVISAAKAKE--QETRISEEIT 544
Query: 380 MREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKVDKKCFADSLEQTNHEKDSE 439
+++ + + E+ + A K+E+ + E+T ++D
Sbjct: 545 KKQKQVTQEAIRQETEITAASMVVVATAKSTKLET----------VPGAQEETTTQQDQM 594
Query: 440 SSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIFPLLGDPTSENKTDEKKIEE 499
+ + T + T P AT + G K ++ +I +
Sbjct: 595 HLSYEKIMKETRK----------TVVPKVIVATPKVKEQDLVSRGREGITTKREQVQITQ 644
Query: 500 KKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE---------------EVVA 544
+K + EK T+ T A++ ET T + + E E VA
Sbjct: 645 EKMRKEAEK-TALSTIAVATAKAKEQETILRTRETMATRQEQIQVTHGKVDVGKKAEAVA 703
Query: 545 NMPEGLTPDLVQEACES---ELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSFE 601
+ + V+E E E + T + Y K + + ++V + PA+
Sbjct: 704 TVVAAVDQARVREPREPGHLEESYAQQTTLEYGYK-ERISAAKVAEPPQRPAS------- 755
Query: 602 ESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKH---EPENPPP 658
E P V P ++ +AP + + + + SS + + + E + H P P
Sbjct: 756 EPHVVPKAVKPRVI-QAPSETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASP 814
Query: 659 YEEAMSVSLKK-------------VSGIKEEIKEPENINAALQETEAPYISIACDLIKET 705
+ +S+ K ++ +++E+ + + +AP + + ET
Sbjct: 815 HFTVSKISVPKTEHGYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPS-----ET 869
Query: 706 KLSAEPAP----DFSDYSEMAKVEQPVPDHSEL 734
++ AEP P F+D + K E V E+
Sbjct: 870 RVRAEPTPLPQFPFADTPDTYKSEAGVEVKKEV 902
Score = 42.7 bits (99), Expect = 0.002
Identities = 215/1084 (19%), Positives = 366/1084 (33%), Gaps = 195/1084 (17%)
Query: 2 EDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEE---------------EDED 46
E L + +V + P + + PE+EE EEEE +E+
Sbjct: 10106 EVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEE 10165
Query: 47 EDLEELEVL-ERKPAAGLSAAPVP-----------------TAPAAGAPLMDFGND---F 85
E + E EVL E KP + APVP AP A P + +
Sbjct: 10166 EFVPEEEVLPEVKPKVPV-PAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRI 10224
Query: 86 VPPAPRGPLPAAPPVAPERQPSWDPS-----PVSSTVPAPSPLSAAAVSPSKLPEDDEPP 140
+ P LP PE +P + P V +P V +PE P
Sbjct: 10225 ILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPV 10284
Query: 141 ARPPPPPPASVSPQ--AEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEP 198
+ PPA VS + E V P A P P PK+ + A+P A
Sbjct: 10285 PKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGR 10344
Query: 199 VIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAAS--FKEHEYLGNLS 256
+ ++ +++ + + V+ +P F+E E+
Sbjct: 10345 TVLEEKVSVAFRQE----VVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEF----- 10395
Query: 257 TVLPTEGTLQENVSEASKEVSEKAKTLLIDR--DLTEFSELEYSEMGSSFSVSPKAESAV 314
++E + V E+ + + R ++ E E+E E + P+ +
Sbjct: 10396 ------HEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKI 10449
Query: 315 IVAN-------PREEIIVKNKDEEEKLVSNNILHNQQE---LPTALTKLVKEDEVVSSEK 364
I PR+E K + +K+V + +E PT + +++ EVV +K
Sbjct: 10450 IPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKK 10509
Query: 365 AKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKVDKKC 424
+K A + E + P ++V K + K+ ++ V +K
Sbjct: 10510 VPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPE----VPPTKVPEVPKAAVPEKK 10565
Query: 425 FADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIFPLLG 484
+++ ++ P PE K+ + PAA
Sbjct: 10566 VPEAI----------PPKPESPPPEVPEAPKE-----VVPEKKVPAA------------- 10597
Query: 485 DPTSENKTDEKKIEEKKAQIVTEKNTST-KTSNPFLVAAQDSETDYVTTDNLTKVTEEVV 543
P + + K+ E ++V EK P + + E V K E +
Sbjct: 10598 -PPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPE--KKVPEAI 10654
Query: 544 ANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSFEES 603
PE P++ +E E L E +EV++E PAA +
Sbjct: 10655 PPKPESPPPEVFEEPEEVALEE---------------PPAEVVEEP-EPAAPPQVTVPPK 10698
Query: 604 EATPSPVLPDIVMEAP--LNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYEE 661
+ P P +V + P VP V+ PL + +PE PP
Sbjct: 10699 KPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPL--------VVPKKPEAPP---- 10746
Query: 662 AMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSEM 721
KV + +E+ PE A ++ E P + ++ K+ L +PA +
Sbjct: 10747 ------AKVPEVPKEV-VPEKKVAVPKKPEVPPAKVP-EVPKKPVLEEKPAVPVPE---- 10794
Query: 722 AKVEQPVPDHSELVEDSSPDSE-------PVDLFSDD-------SIPDVPQK--QDETVM 765
+ E P P+ E E+ +P+ E PV + ++ ++P+ P+K ++ V
Sbjct: 10795 -RAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVP 10853
Query: 766 LVKESLT----ETSFESMIEYENKEKLSAL-PPEGGKPYLESFKLSLDNTK---DTLLPD 817
++K+ E E +IE K KL PP P E K + K +P+
Sbjct: 10854 VIKKPEAPPPKEPEPEKVIE---KPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPE 10910
Query: 818 EVSTLSKKEKIPLQMEELSTAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISS 877
+ K E PL++ V L ++ + +E +E P +
Sbjct: 10911 KPQVPEKVELTPLKVPGGEKKVRK---LLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPK 10967
Query: 878 KTDSFSKLA-------REYTDLEVSHKSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEE 930
K + K A + ++EV ++ +P + L +PK E
Sbjct: 10968 KLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEA 11027
Query: 931 KISFSDDFSKNGSATSKVLLLPPDVSALATQAEI----ESIVKPKVLVKEAEKKLPSDTE 986
++ T + P V + +AE E KPK +K KK PS E
Sbjct: 11028 EVKTIKPPPVEPEPTP--IAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIE 11085
Query: 987 KEDR 990
E R
Sbjct: 11086 AERR 11089
Score = 39.7 bits (91), Expect = 0.017
Identities = 60/255 (23%), Positives = 82/255 (32%), Gaps = 44/255 (17%)
Query: 1 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEE-----EEDEDEDLEELEVL 55
+E+ P+ ++SP P ++ PE+E EEE+ EE+E E
Sbjct: 10784 LEEKPAVPVPERAESP--PPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPE 10841
Query: 56 ERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQP------SWD 109
E K PV P A P + P P PP AP ++
Sbjct: 10842 EPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLK 10901
Query: 110 PSPVSSTVPAPSPLSAAAVSPSKLPEDDEP-----PARPPPPP------------PASVS 152
P P ++P K+P ++ P R P P P
Sbjct: 10902 AIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEE 10961
Query: 153 PQAEP----------VWTPPAPAPAAPPSTPAAPKRR---GSSGSVDETLFALP-AASEP 198
P+ EP V PP P P P KR V E A+P A EP
Sbjct: 10962 PKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEP 11021
Query: 199 VIRSSAENMDLKEQP 213
+ AE +K P
Sbjct: 11022 KPKPEAEVKTIKPPP 11036
Score = 38.5 bits (88), Expect = 0.038
Identities = 157/873 (17%), Positives = 298/873 (34%), Gaps = 180/873 (20%)
Query: 50 EELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWD 109
+E+++ + P S P+PT P P + +PP P+P P E++P
Sbjct: 8926 KEIKLELKPPDIPDSRVPIPTMPIRAVP-----PEEIPPVVAPPIPLLLPTPEEKKP--- 8977
Query: 110 PSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAP 169
P V+ + +D A+ P ++P+ E V PP P P
Sbjct: 8978 ------------PPKRIEVTKKAVKKD----AKKVVAKPKEMTPREEIVKKPPPPTTLIP 9021
Query: 170 PSTPAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLL 229
P E + A E I + +++++ +
Sbjct: 9022 AKAP-------------EIIDVSSKAEEVKIMTITRKKEVQKE------------KEAVY 9056
Query: 230 ETAASLPSLSPLSAASFKE-HEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRD 288
E ++ + SF+E ++ L P E E E +E+ +AK + +
Sbjct: 9057 EKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEW 9116
Query: 289 LTEFSE-LEYSEMGSSFSVSPKAESAVIVANPREEIIVKNK----DEEEKLVSNNILHNQ 343
+F E EY E + + E A E+I K + E+ V + +
Sbjct: 9117 EEDFEEGQEYYEREEGYD---EGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKK 9173
Query: 344 QELPTALTKLVKEDEVVSSEKAKDSFNEKRVAV----------------EAPMREEYADF 387
P K++K+ + EK E++V V P++EE +
Sbjct: 9174 APPP---PKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEV 9230
Query: 388 K-PFERVWEVKDSKEDSDMLAAGGKIESNLESKVDKKCFADSLEQTNHEKDSESSNDDTS 446
K P ++ S+E + + S +V K+ E+ H S+
Sbjct: 9231 KVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVT---EEKIHVAISKRVEPPPK 9287
Query: 447 FPSTPEGIKDRSGAYITCAPFNPAATESIATNIFPLLGDPTSENK--------------- 491
P PE A + P E A + + P E K
Sbjct: 9288 VPELPEKPAPEEVAPVPI----PKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPK 9343
Query: 492 ---TDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTEEVVANMPE 548
+K + E+K + K K + P V + + VT + +T VT+
Sbjct: 9344 VPEVPKKPVPEEKIPVPVAKK---KEAPPAKV--PEVQKGVVTEEKITIVTQR------- 9391
Query: 549 GLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSFEESEATPS 608
+E+ + E+ K+ E K + EV PA P EE A P
Sbjct: 9392 -------EESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPV 9444
Query: 609 PVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYEEAMSVSL- 667
PV +P + V+ +++ E EE +S ++
Sbjct: 9445 PV-----------------------AKKAPPPRAEVSKKTVVEEKRFVA--EEKLSFAVP 9479
Query: 668 KKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSEMAKVEQP 727
++V + E+ E + + +E ++ + +E + E + ++Y M + E+
Sbjct: 9480 QRVEVTRHEVSAEEEWSYSEEEE-----GVSISVYREEEREEEEEAEVTEYEVMEEPEEY 9534
Query: 728 VPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMIEYENKEK 787
V + + ++EP +V ++Q++ ++L + I + +E
Sbjct: 9535 VVEEKLHIISKRVEAEPA---------EVTERQEKKIVL----------KPKIPAKIEEP 9575
Query: 788 LSALPPEGGKPYLESFKL-----SLDNTKDTLLPDEVSTLSKKEKIP---LQMEELSTAV 839
A PE K + K+ + +P+E ++K+P ++MEE A
Sbjct: 9576 PPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAK 9635
Query: 840 YSNDDLFISKEAQIRETETFSDSSPIEIIDEFP 872
+ + I++E ++ T ++ P + E P
Sbjct: 9636 VTERHMQITQEEKVLVAVTKKEAPPKARVPEEP 9668
Score = 38.5 bits (88), Expect = 0.038
Identities = 64/291 (21%), Positives = 102/291 (35%), Gaps = 36/291 (12%)
Query: 99 PVAPERQPSWDPSPVSST-VPAPSPLSAAAVSPSKLPEDDE----PPARPPPPPPASVSP 153
P PE P P PV VP + P+K+PE P P P P A V
Sbjct: 10975 PAVPEPPP---PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKT 11031
Query: 154 QAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDET------LFALPAASEPVIRSSAENM 207
P P AAP + P K+ + +E + +P + I +
Sbjct: 11032 IKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERR-- 11089
Query: 208 DLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEHEYLGNL---------STV 258
K +PG+ ++ P A L + + E E++G+ ST
Sbjct: 11090 --KLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTA 11147
Query: 259 LPTEGTLQENVSEASKE----VSEKAKTLLIDRDLTEFSELE-YSEMGSSFSVSPKAESA 313
+ T N+ E+ K + K +ID L++ E +G+ K +A
Sbjct: 11148 ITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGN----KEKTSTA 11203
Query: 314 VIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVVSSEK 364
+V VK +EE +V L+ EL + ++D + EK
Sbjct: 11204 KLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDVVWRKDGKIVVEK 11254
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 67.4 bits (163), Expect = 8e-11
Identities = 99/374 (26%), Positives = 136/374 (36%), Gaps = 73/374 (19%)
Query: 2 EDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEED---------EDEDLEEL 52
E +S + +S PP P+ A R E + EE EE+ + +E L
Sbjct: 445 ERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEIL 504
Query: 53 EVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVP-----PAPRGPLPA------APPVA 101
V P+ G AP P P G+P D P P P PLP APP A
Sbjct: 505 PVAVATPSGG--DAPTPGVPT-GSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSA 561
Query: 102 PERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTP 161
P + P SP P P+P LP D PP PPPPPP + PV P
Sbjct: 562 PPQAPPLPGSPE----PPPAP---------PLPGDLPPPPPPPPPPPGTDG----PVPPP 604
Query: 162 PAPAPAAPPSTPAAPKRRGS-------SGSVDETLFALPAASEPVIRSS-------AENM 207
P P P P P A RR S + +T F +P + ++ S E
Sbjct: 605 PPPPPPPPGGPPDALGRRDSELGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTVFTELN 664
Query: 208 DLKEQPGNTISAGQEDF------PSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPT 261
D K +S +E F PS+ L S + S A+ E NL+ L
Sbjct: 665 DEKVLQELDMSDFEEQFKTKSQGPSLDLSALKSKAAQKAPSKATLIEANRAKNLAITLRK 724
Query: 262 EGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVANPRE 321
E + +A + +A L L F EY E ++I RE
Sbjct: 725 GNLGAERICQAIEAYDLQALGLDFLELLMRFLPTEY-------------ERSLITRFERE 771
Query: 322 EIIVKNKDEEEKLV 335
+ ++ EE++ +
Sbjct: 772 QRPMEELSEEDRFM 785
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 66.6 bits (161), Expect = 1e-10
Identities = 132/559 (23%), Positives = 205/559 (36%), Gaps = 60/559 (10%)
Query: 30 EPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPA---------AGAPLMD 80
E E +EEE +EEE E+E+ E E + P A +A+P A + A A +
Sbjct: 475 EKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE 534
Query: 81 FGNDFVPPAPRGPLPAAPPV-----------APERQPSWDPSPVSSTVPAPSPLSAAAVS 129
P + P A P +PE++ + P+ V S A SP A S
Sbjct: 535 KEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 594
Query: 130 P--SKLPEDDEPPARPPPPPPASV-SPQAEPVWTP---PAPAPAAPPSTPAAPKRRGSSG 183
P +K PE + P + PA SP E +P +P A P+ A +
Sbjct: 595 PAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654
Query: 184 SVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAAS-LPSLSPLS 242
E + A PV ++ A++ + + P + E S + E A S + SP+
Sbjct: 655 PEKEEAKSPEKAKSPV-KAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVK 713
Query: 243 AASFKEHEYLGNLSTVLPTEGTLQENVSEASK-----EVSEKAKTLLIDRDLTEFSELEY 297
+ + + T + V E +K + EKAKTL D E
Sbjct: 714 EEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL--DVKSPEAKTPAK 771
Query: 298 SEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKED 357
E S P+ + + + K+ +E+ + ++E+ + + + K
Sbjct: 772 EEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQ 831
Query: 358 EVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVW------EVKDSKEDSDMLAAGGK 411
EV E K + EK A P EE D K E +V++ KE + K
Sbjct: 832 EVKVKEPPKKAEEEK--APATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESK 889
Query: 412 IESNLESKVDKKCFADSLEQTNHEKDSESS---NDDTSFPSTPEGIKDRSGAYITCAPFN 468
+E+ E DKK + EK++ + +D E K P
Sbjct: 890 VEAKKEEAEDKK------KVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 943
Query: 469 PAATESIATNIFPLLGDPTSE--NKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQ-DS 525
PA + A P D E K +EK E KA+ +K S + S P A+ S
Sbjct: 944 PAEKKEAA----PEKKDTKEEKAKKPEEKPKTEAKAK-EDDKTLSKEPSKPKAEKAEKSS 998
Query: 526 ETDYVTTDNLTKVTEEVVA 544
TD + K TE+ A
Sbjct: 999 STDQKDSKPPEKATEDKAA 1017
Score = 50.1 bits (118), Expect = 1e-05
Identities = 111/544 (20%), Positives = 213/544 (39%), Gaps = 65/544 (11%)
Query: 346 LPTALTKLVKED---EVVSSEKAK--DSFNEKRVAVEAPMREEYADFKPFERVWEVKDSK 400
LP L K+ +V S EK K + ++ V VE E + E E K++K
Sbjct: 422 LPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEE--EEKEAK 479
Query: 401 EDSDMLAAGGKIESNLESKVDKKCFADSLEQTNHEKDSESS-NDDTSFPS---TPEGIKD 456
E+ GG+ E E ++ + E + EK+++S ++ P+ +PE +
Sbjct: 480 EEEGKEEEGGE-EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEA 538
Query: 457 RSGAYITCAPFNPAATESIATNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSN 516
+S A + +P +S A +++ + K E+++A+ E + K +
Sbjct: 539 KSPAEVK----SPEKAKSPAKE--------EAKSPPEAKSPEKEEAKSPAEVKSPEKAKS 586
Query: 517 PFLVAAQDSETDYVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETK 576
P A+ S + + + +E + E +P V+E +S + K TK
Sbjct: 587 PAKEEAK-SPAEAKSPEKAKSPVKEEAKSPAEAKSP--VKEEAKSPAEVKSPEKAKSPTK 643
Query: 577 MDLVQTSEVMQESLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSS 636
+E+ P P EE+++ P + EA + A + V +
Sbjct: 644 ----------EEAKSPEKAKSPEKEEAKS-PEKAKSPVKAEA---KSPEKAKSPVKAEAK 689
Query: 637 SPLEASSVNYESIKHEPENPPPYEEAMSVSLKKVSGIKEEIKEPENINAALQE------- 689
SP +A S E K + P +E K S +KEE K PE + ++E
Sbjct: 690 SPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK 749
Query: 690 TEAPYISIACDL---------IKETKLSAEPAPDFSDYSEMAKVEQPVPDHSELVEDSSP 740
++P + D+ +E + A+ P+ + +V+ P S L ED+
Sbjct: 750 AKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKA 809
Query: 741 DSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFE------SMIEYENKEKLSALPPE 794
+ + + P V +++ + VKE + E E ++ +K A E
Sbjct: 810 PEKEIPKKEEVKSP-VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE 868
Query: 795 GGKPYLESFK-LSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVYSNDDLFISKEAQI 853
KP +E K +++ K++ + + K+K+P +E V +D ++ ++
Sbjct: 869 APKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEV 928
Query: 854 RETE 857
+ E
Sbjct: 929 AKKE 932
Score = 31.2 bits (69), Expect = 6.1
Identities = 39/171 (22%), Positives = 64/171 (37%), Gaps = 14/171 (8%)
Query: 19 PQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPL 78
P+ A + + P+ EE+++ ++EE ++ + +V E+K A P A
Sbjct: 839 PKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKE----PAVEKPKESKVEAKK 894
Query: 79 MDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDE 138
+ + P P PA V + +P + V P A A PSK E E
Sbjct: 895 EEAEDKKKVPTPEKEAPAKVEVKEDAKPK-----EKTEVAKKEPDDAKAKEPSKPAEKKE 949
Query: 139 -PPARPPPPPPASVSPQAEPVWTPPAPAP----AAPPSTPAAPKRRGSSGS 184
P + + P+ +P A + PS P A K SS +
Sbjct: 950 AAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSST 1000
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 66.6 bits (161), Expect = 1e-10
Identities = 81/265 (30%), Positives = 103/265 (38%), Gaps = 60/265 (22%)
Query: 2 EDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEE---EEEEEEEDEDEDLEELEVLERK 58
E + S SSS+S P EDEEE EEEEEE+E+E + E +
Sbjct: 1114 ESSESSEFESSSESSPSSS-----------EDEEEVVAREEEEEEEEEEMVAEESMASAG 1162
Query: 59 PAA----GLSAAPVPTAPAAGAPLM----DFGNDFVPPAPRGPLPAAPPV-------APE 103
P G AA P APA + M D + V P R + PP+ A
Sbjct: 1163 PEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADS 1222
Query: 104 RQPSWDPSP-------VSSTVPAPSPLSAAAVSPSKLPEDD-----EPPAR--------- 142
R+P +P +S PA + +SP + PE D EPP
Sbjct: 1223 REPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPL 1282
Query: 143 PPPPPPASVSPQAEPVWT-------PPAP-APAAPPSTPAAPKRRGSSGSVDETLFALPA 194
PPP PP SP EP T PP P A PP TP S S ET+ A P
Sbjct: 1283 PPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQST-ETVPATPG 1341
Query: 195 ASEPVI-RSSAENMDLKEQPGNTIS 218
P+ SS ++ + PG+ S
Sbjct: 1342 GEPPLSGGSSGLSLSSPQVPGSPFS 1366
Score = 60.8 bits (146), Expect = 7e-09
Identities = 54/202 (26%), Positives = 74/202 (36%), Gaps = 53/202 (26%)
Query: 1 MEDLDQSPLVSSSDS-----------PPRPQP-------------AFKYQFVREPEDEEE 36
+ED+ +PL S + PP P P A R P E+
Sbjct: 569 LEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKM 628
Query: 37 EEEEEEEDEDEDLEELEVLERKPAAGLSAA--PVPTAPAAGAPLMDFGNDFVPPAPRGPL 94
+E ++ ED ++ + E+ P+A +++A P P GA + + P P P
Sbjct: 629 DEGQQSSGEDMEISDDEM----PSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPP 684
Query: 95 PAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQ 154
P PP+ P P P P P PL P PPPPPPA +
Sbjct: 685 PGFPPLPPPPPPP----PPQPGFPMPPPL----------------PPPPPPPPPAHPAVT 724
Query: 155 AEPVWTPPAPAPAAPPSTPAAP 176
P PP PAP P P P
Sbjct: 725 VPP---PPLPAPPGVPPPPILP 743
Score = 38.9 bits (89), Expect = 0.029
Identities = 42/170 (24%), Positives = 64/170 (37%), Gaps = 27/170 (15%)
Query: 93 PLPAAPPVAPERQPSWDP--SPVSSTVPAPS-PLSAAAVSPSKLPEDDEPPARPPPPPPA 149
P PA AP + ++ P +PV+ P P P + AA E PA PPP PPA
Sbjct: 382 PPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPA-PPPLPPA 440
Query: 150 SVSPQAEPVWTPPAPAP-----------------AAPPSTPAAPKRRGSSGSVDETLFAL 192
+ +P TPP P P P +P P S ++ +L
Sbjct: 441 EPLAKEKP-GTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSL 499
Query: 193 PAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLS 242
+ E +++ + +P + E P ++S LSPL+
Sbjct: 500 DSRIEMLLKEQRTKLLFLREPDSDTELQMEGSP-----ISSSSSQLSPLA 544
Score = 37.4 bits (85), Expect = 0.086
Identities = 67/325 (20%), Positives = 116/325 (35%), Gaps = 23/325 (7%)
Query: 347 PTALTKLVKEDEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDML 406
P L +EDE S + ++S E+ A E E+ D +R E ++ ED+ +
Sbjct: 1026 PLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRD-ESENDDEDTALS 1084
Query: 407 AAGGKIESNLESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAP 466
A K E + + + E T+ + SESS ++S S+P +D
Sbjct: 1085 EASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEE 1144
Query: 467 FNPAATESIATNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSE 526
E +A G E +E + + + + D E
Sbjct: 1145 EEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAV----------DSLGMEEEVDIE 1194
Query: 527 TDYVTTDNLTKVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVM 586
T+ V + + +E + D + E L++ ++ E V+ +
Sbjct: 1195 TEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPL 1254
Query: 587 QESLYPAAQLCPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNY 646
P L E E P +LP + ++ PL P S P P E + ++
Sbjct: 1255 SPERAPEHDL-----EVEPEPPMMLP-LPLQPPLPPPRPPRPPS---PPPEP-ETTDASH 1304
Query: 647 ESIKHEP--ENPPPYEEAMSVSLKK 669
S+ EP E+ PP+ + SL K
Sbjct: 1305 PSVPPEPLAEDHPPHTPGLCGSLAK 1329
Score = 37.0 bits (84), Expect = 0.11
Identities = 46/182 (25%), Positives = 69/182 (37%), Gaps = 49/182 (26%)
Query: 75 GAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSW-DPSPVSSTVPAPSPLSAAAVSPSKL 133
G+P+ + P AP G QP + P+P SS PS +SP+ L
Sbjct: 530 GSPISSSSSQLSPLAPFGT---------NSQPGFRGPTPPSSR---PSSTGLEDISPTPL 577
Query: 134 PEDDE-----------PPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSS 182
P+ DE PP P PP PA + Q V + R +S
Sbjct: 578 PDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEV------------ALDLVGDRTPTS 625
Query: 183 GSVDETLFALPAASEPVIRSSAENMDLK--EQPGNTISAGQEDFPSVLLETAASLPSLSP 240
+DE +SS E+M++ E P I++ P V+ AA++ + S
Sbjct: 626 EKMDEGQ-----------QSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSV 674
Query: 241 LS 242
L+
Sbjct: 675 LA 676
Score = 36.2 bits (82), Expect = 0.19
Identities = 54/188 (28%), Positives = 67/188 (35%), Gaps = 28/188 (14%)
Query: 66 APVPTAPAAGAPLMDFGNDF----VPPAPRGPL--PAAPPVAPERQPSWDP--SPVSSTV 117
AP P+ + G P G DF P GPL P P R P SPV
Sbjct: 1369 APSPSLSSGGLPRTP-GRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLET 1427
Query: 118 PAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPP---STPA 174
P PL P LP AR P P P + PAP + PP P
Sbjct: 1428 GLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLL----------PAPLASCPPPMKRKPG 1477
Query: 175 APKRRGSSG-SVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLE-TA 232
P+R S S+D L PA + E + L QP + D +V L+
Sbjct: 1478 RPRRSPPSMLSLDGPLVRPPAGA----ALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRN 1533
Query: 233 ASLPSLSP 240
A +P+ P
Sbjct: 1534 AGIPAPPP 1541
Score = 34.3 bits (77), Expect = 0.73
Identities = 14/27 (51%), Positives = 21/27 (77%)
Query: 30 EPEDEEEEEEEEEEDEDEDLEELEVLE 56
E E+E EEEEEEE+D+D+D ++ + E
Sbjct: 1049 EEEEEAEEEEEEEDDDDDDSDDRDESE 1075
Score = 32.7 bits (73), Expect = 2.1
Identities = 40/149 (26%), Positives = 45/149 (30%), Gaps = 40/149 (26%)
Query: 66 APVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSA 125
AP P P APL PP R P P R P PS +S P P +
Sbjct: 1453 APTPLPPLLPAPLASCP----PPMKR------KPGRPRRSP---PSMLSLDGPLVRPPAG 1499
Query: 126 AAVSPSKL-----------PEDDEP----------------PARPPPPPPASVSPQAEPV 158
AA+ L P +P P PP PPP P EP
Sbjct: 1500 AALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPT 1559
Query: 159 WTPPAPAPAAPPSTPAAPKRRGSSGSVDE 187
P PS P RG +E
Sbjct: 1560 KLPFKELDNQWPSEAIPPGPRGRDEVTEE 1588
Score = 32.0 bits (71), Expect = 3.6
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Query: 134 PEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFALP 193
P+D A PPP A+ +P + ++P A P P P + G+ D F
Sbjct: 372 PQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRA 431
Query: 194 AASEPVIRSSAENMDLKEQPG 214
A P+ AE + KE+PG
Sbjct: 432 PAPPPL--PPAEPL-AKEKPG 449
Score = 32.0 bits (71), Expect = 3.6
Identities = 13/20 (65%), Positives = 17/20 (85%)
Query: 29 REPEDEEEEEEEEEEDEDED 48
+E +EEEE EEEEE+ED+D
Sbjct: 1045 QESTEEEEEAEEEEEEEDDD 1064
Score = 30.8 bits (68), Expect = 8.0
Identities = 14/25 (56%), Positives = 16/25 (64%)
Query: 24 KYQFVREPEDEEEEEEEEEEDEDED 48
K E E EEEEE EEE+E+ED
Sbjct: 1038 KESLSEEQESTEEEEEAEEEEEEED 1062
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 66.2 bits (160), Expect = 2e-10
Identities = 73/262 (27%), Positives = 98/262 (37%), Gaps = 29/262 (11%)
Query: 4 LDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGL 63
L++SPL +SPP PA + PE EE EEL A+ L
Sbjct: 515 LEESPLSPPEESPP--SPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRL 572
Query: 64 SA-------------APVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDP 110
S +P+ P A F + P P + PP A P +
Sbjct: 573 SPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPED 632
Query: 111 SPVS--------STVPAPSPLSAAAVSPSKLPEDDEPPARPPPPP-PASVSPQAEPVWTP 161
SP+S S P S LS V P +E P PPP P S P+A + P
Sbjct: 633 SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPP 692
Query: 162 PAPAPAAPP--STPAAPKRRGSSGSVD-ETLFALPAASEPVIRSSAENMDLKEQPGNTIS 218
P +P +PP +PA+P S S+ E LP EP + +E L +P
Sbjct: 693 PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHL 752
Query: 219 AGQEDFPSVLLETAASLPSLSP 240
+ + + P L A P LSP
Sbjct: 753 SPRPEEPH--LSPQAEEPHLSP 772
Score = 53.1 bits (126), Expect = 2e-06
Identities = 55/203 (27%), Positives = 76/203 (37%), Gaps = 19/203 (9%)
Query: 31 PEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPP-- 88
P +E EE E L P L A+P+P A PL + + PP
Sbjct: 443 PPEESPLSPPPEESPTSPPPEASRLSPPPEE-LPASPLPEALHLSRPLEE--SPLSPPPE 499
Query: 89 -APRGPLPAAPPVAPERQPSWDPSPVSSTVPA-PSPLSAAAVSPSKLPEDDEPPARPPPP 146
+P P P + P +P + P S PA +PLS + P +E P PPP
Sbjct: 500 ESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPE 559
Query: 147 P-PASVSPQAEPVWTPPAPAPAAPP--STPAAPKRRGSSGSVDETLFALPAASEPVIRSS 203
P S P+A + PP +P +PP +P +P S P E +
Sbjct: 560 ELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASR--------LFPPFEESPLSPP 611
Query: 204 AENMDLKEQP-GNTISAGQEDFP 225
E L P + +S ED P
Sbjct: 612 PEESPLSPPPEASRLSPPPEDSP 634
Score = 52.8 bits (125), Expect = 2e-06
Identities = 51/186 (27%), Positives = 67/186 (36%), Gaps = 27/186 (14%)
Query: 2 EDLDQSPLVSS-------SDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEV 54
E+L SPL + +SP P P P E E+ L E
Sbjct: 472 EELPASPLPEALHLSRPLEESPLSPPPE------ESPLSPPPESSPFSPLEESPLSPPEE 525
Query: 55 LERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVS 114
PA +P P A P F + P P + PP A P + SP+S
Sbjct: 526 SPPSPALETPLSPPPEASPLSPP---FEESPLSPPPEELPTSPPPEASRLSPPPEESPMS 582
Query: 115 STVPAPSPLSAAAVSPSKLPEDDEPPARPPP------PPPA----SVSPQAEPVWTPPAP 164
P SP+S + P +E P PPP PPP S P+ P+ PP
Sbjct: 583 PP-PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEE 641
Query: 165 APAAPP 170
+P +PP
Sbjct: 642 SPMSPP 647
Score = 49.7 bits (117), Expect = 2e-05
Identities = 78/322 (24%), Positives = 105/322 (32%), Gaps = 36/322 (11%)
Query: 2 EDLDQSPLVSSSDSPPRPQ-----PAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLE 56
ED SP S P P+ P + P +E EE E L
Sbjct: 631 EDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLS 690
Query: 57 RKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSST 116
P ++ P +PA+ P + + +P PLP P + P + P S
Sbjct: 691 PPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSE-----GPHLSP 745
Query: 117 VPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAP 176
P LS P P+ +EP P P P + EP +P A P P
Sbjct: 746 RPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQ----- 800
Query: 177 KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFP--SVLLETAAS 234
E L P EP + E L QP + + Q + P S E +
Sbjct: 801 ---------PEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHL 851
Query: 235 LPSLS--PLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEF 292
P L PLS K E G P E L E S LL + L+E
Sbjct: 852 SPELEKPPLSPRPEKPPEEPGQCPA--PEELPLFPPPGEPS------LSPLLGEPALSEP 903
Query: 293 SELEYSEMGSSFSVSPKAESAV 314
E S + +SP E ++
Sbjct: 904 GEPPLSPLPEELPLSPSGEPSL 925
Score = 48.5 bits (114), Expect = 4e-05
Identities = 48/158 (30%), Positives = 64/158 (40%), Gaps = 25/158 (15%)
Query: 56 ERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSS 115
E KP L A V P APL + +PP PL +PP PE P+ P S
Sbjct: 415 EAKP---LGKAGVQLEPQLEAPLNE-EMPLLPPPEESPL--SPP--PEESPTSPPPEASR 466
Query: 116 TVPAPSPLSAAAV------------SPSKLPEDDEPPARPP---PPPPASVSPQAEPVWT 160
P P L A+ + SP P ++ P + PP P P SP + P +
Sbjct: 467 LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEES 526
Query: 161 PPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEP 198
PP+PA P S P P+ S +E+ + P P
Sbjct: 527 PPSPALETPLSPP--PEASPLSPPFEESPLSPPPEELP 562
Score = 47.8 bits (112), Expect = 6e-05
Identities = 48/197 (24%), Positives = 71/197 (36%), Gaps = 39/197 (19%)
Query: 5 DQSPLVSSSDSP---PRPQPA-FKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA 60
++S L S+ P PRP+ + + + P E+ EE + EEL + P
Sbjct: 829 EESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFP--PP 886
Query: 61 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPS--PVSSTVP 118
S +P+ PA P P PLP P++P +PS P P P
Sbjct: 887 GEPSLSPLLGEPALSEP---------GEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPP 937
Query: 119 APSPLSAAAVSPSKLPEDD----------------------EPPARPPPPPPASVSPQAE 156
SP+ AA P+ P + E P PPP +
Sbjct: 938 PLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVP 997
Query: 157 PVWTPPAPAPAAPPSTP 173
P+ PP+P P++P
Sbjct: 998 PMILPPSPGSPVGPASP 1014
Score = 43.1 bits (100), Expect = 0.002
Identities = 38/115 (33%), Positives = 48/115 (41%), Gaps = 10/115 (8%)
Query: 90 PRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPA 149
P P P PP P + P+ + P+ PS LS P+ L E EPP P P
Sbjct: 859 PLSPRPEKPPEEPGQCPAPEELPLFPPPGEPS-LSPLLGEPA-LSEPGEPPLSPLPEE-L 915
Query: 150 SVSPQAEPVWTP------PAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEP 198
+SP EP +P P P P +P T AAP G + E F S+P
Sbjct: 916 PLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGEL-EYPFGAKGDSDP 969
Score = 42.0 bits (97), Expect = 0.003
Identities = 59/207 (28%), Positives = 73/207 (35%), Gaps = 30/207 (14%)
Query: 56 ERKPAAGLSAAPVPTAP---AAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDP-- 110
E PA L+ +P P+ P G+ + + P P+ P P + P R DP
Sbjct: 2351 EPPPAQALAPSP-PSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFS 2409
Query: 111 -------SPVSSTVP-APSPLSAAAVSPSKL-PEDDEP-PARPPPPPPASVSPQAEPVWT 160
S SS P P PLSA A PS + P P P PP P S P A P+
Sbjct: 2410 RVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFA-PLHK 2468
Query: 161 PPAPAPAAPPSTPAAPKRRGS-------SGSVDETLFALPAASEPVIRSSAENMDLKEQP 213
PP P P P + GS +G L A PA S + + P
Sbjct: 2469 PPRPQP------PEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSP 2522
Query: 214 GNTISAGQEDFPSVLLETAASLPSLSP 240
G G A PSL P
Sbjct: 2523 GTGAFVGTPSPMRFTFPQAVGEPSLKP 2549
Score = 40.8 bits (94), Expect = 0.008
Identities = 49/227 (21%), Positives = 81/227 (35%), Gaps = 38/227 (16%)
Query: 10 VSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVP 69
V ++D P Q A K ++ +++ E + ++ + ++ +PA L P P
Sbjct: 2052 VPAADKAPYLQKA-KDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQP 2110
Query: 70 TA----PAAGAPLMDFGNDFVPPA-----------PRGPLPAAPPVAPERQPSWDPSPVS 114
A P A AP + G+ P P G +P P +P P V
Sbjct: 2111 GALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPG--PDSPGELFLKLPPQVP 2168
Query: 115 STVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAP----P 170
+ VP+ P A P + PP PP P P Q + P P
Sbjct: 2169 AQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHT 2228
Query: 171 STPAAPKRRGSSGSVDETLFALPAASEPVIR---SSAENMDLKEQPG 214
+ P P+ + P+ +P ++ S +N+ + E PG
Sbjct: 2229 TPPGTPRHQ-------------PSTPDPFLKPRCPSLDNLAVPESPG 2262
Score = 39.7 bits (91), Expect = 0.017
Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 87 PPAPRGPLPAAPPVAPERQPSWDP---SPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARP 143
PP+P P PA+PP P + +P PV S +P S +A P P ++ +RP
Sbjct: 4917 PPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRP 4976
Query: 144 P 144
P
Sbjct: 4977 P 4977
Score = 36.6 bits (83), Expect = 0.15
Identities = 26/101 (25%), Positives = 39/101 (38%), Gaps = 10/101 (9%)
Query: 92 GPLPAAPPVAPERQPSWDPSPVSSTV-PAPSPLSAAAVSPSKLPEDDEPPARPPPPPPAS 150
GP P PP P + PV V P P P S P++ + P++ P P
Sbjct: 4280 GPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSS---------PQEPKRPSQLPSPSSQL 4330
Query: 151 VSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFA 191
+ P P P P P P + ++ + +TLF+
Sbjct: 4331 PTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFS 4371
Score = 36.2 bits (82), Expect = 0.19
Identities = 45/193 (23%), Positives = 75/193 (38%), Gaps = 19/193 (9%)
Query: 593 AAQLCPSFEESEATPSP------VLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNY 646
A+ L P FEES +P P P+ +P P + P S P EAS + +
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRL-F 600
Query: 647 ESIKHEPENPPPYEEAMS--VSLKKVSGIKEE--IKEPENINAALQETEA------PYIS 696
+ P +PPP E +S ++S E+ + P + E P +S
Sbjct: 601 PPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660
Query: 697 IACDLIKETKLSAEPAPDFSDYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDV 756
+E+ LS P P+ S S + + P + P+ P +DS+ +
Sbjct: 661 RLSPPPEESPLS--PPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718
Query: 757 PQKQDETVMLVKE 769
P ++ + L +E
Sbjct: 719 PLEESPLLPLPEE 731
Score = 36.2 bits (82), Expect = 0.19
Identities = 63/268 (23%), Positives = 88/268 (32%), Gaps = 49/268 (18%)
Query: 65 AAPVPTAPAAGAPLMDFGND------FVPPAPRGPLPAAPPV-----------------A 101
AAP+ P + P + + +PP+P P+ A P+
Sbjct: 974 AAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLV 1033
Query: 102 PERQPSWDPSPVSSTVPAPSPLS--AAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVW 159
P+ P SP + + PSPLS V S E E P P EP
Sbjct: 1034 PQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPEC---PALEPSA 1090
Query: 160 TPPAPAPAAPPSTPA---APKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNT 216
T P P+P S PA AP SG ++T +D + PG+
Sbjct: 1091 TSPLPSPMGDLSCPAPSPAPALDDFSGLGEDT----------------APLDGIDAPGSQ 1134
Query: 217 ISAGQEDFPSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEV 276
GQ S+ E S L P A E +G+ E E V
Sbjct: 1135 PEPGQTP-GSLASELKGSPVLLDPEELAPVTPMEVYPECKQT-AGQGSPCEEQEEPRAPV 1192
Query: 277 SEKAKTLLIDRDLTEFSELEYSEMGSSF 304
+ TL+ + E S L + +SF
Sbjct: 1193 APTPPTLIKSDIVNEISNLSQGDASASF 1220
Score = 35.8 bits (81), Expect = 0.25
Identities = 33/122 (27%), Positives = 48/122 (39%), Gaps = 18/122 (14%)
Query: 37 EEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPA 96
+ E E++ + + L EL + ++ L A AAGA PP G P+
Sbjct: 2674 QTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGA--------VGPPGSWGAEPS 2725
Query: 97 APPVAPERQPSWDPSPVSSTVPA-------PSPLSAAAVSPSKLPEDDEPPARPPPPPPA 149
+P Q S +P + T PS LS + P P DD PPP P+
Sbjct: 2726 SPAF---EQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPS 2782
Query: 150 SV 151
S+
Sbjct: 2783 SM 2784
Score = 35.8 bits (81), Expect = 0.25
Identities = 24/84 (28%), Positives = 30/84 (35%), Gaps = 13/84 (15%)
Query: 102 PERQPSWDPSPVSSTVPA-------PSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQ 154
P ++P SP+ + P P + P PP P PP S P
Sbjct: 4242 PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPV 4301
Query: 155 AEPVWTPPAPAPAAPPSTPAAPKR 178
PV P PPS+P PKR
Sbjct: 4302 LGPV------HPTPPPSSPQEPKR 4319
Score = 34.3 bits (77), Expect = 0.73
Identities = 25/82 (30%), Positives = 32/82 (39%), Gaps = 7/82 (8%)
Query: 102 PERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTP 161
P +PS PSP+ APSP S +LP EP A PP P P ++ E
Sbjct: 4910 PPEEPSPPPSPL-----APSPASPPTEPLVELP--TEPLAEPPVPSPLPLASSPESARPK 4962
Query: 162 PAPAPAAPPSTPAAPKRRGSSG 183
P P P+ + G
Sbjct: 4963 PRARPPEEGEDSRPPRLKKWKG 4984
Score = 33.9 bits (76), Expect = 0.95
Identities = 69/303 (22%), Positives = 98/303 (32%), Gaps = 44/303 (14%)
Query: 11 SSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPT 70
SSS SP P+P F P + + + R P A L P P
Sbjct: 2419 SSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQS-----RDPFAPLHKPPRPQ 2473
Query: 71 AP-----AAGAPLMDFGNDFVPPA-PRGPLPAAPPVAPERQP-SWDPSP-VSSTVPAPSP 122
P A G P A P GP P QP ++ SP + V PSP
Sbjct: 2474 PPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSP 2533
Query: 123 LSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPST---------- 172
+ P + EP +PP P P P P P P ST
Sbjct: 2534 MRFTF--PQAV---GEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFH 2588
Query: 173 PAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDL-------KEQPGNTISAGQEDFP 225
P+ SSGS E+ P V+ A + L ++ G T + + P
Sbjct: 2589 PSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDP 2648
Query: 226 SVLLETAASL--------PSLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVS 277
+ ++ + P +S LS ++ L +L + +Q N KE +
Sbjct: 2649 GTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQ-QIQRNTLRQEKETA 2707
Query: 278 EKA 280
A
Sbjct: 2708 AAA 2710
Score = 33.5 bits (75), Expect = 1.2
Identities = 26/81 (32%), Positives = 32/81 (39%), Gaps = 19/81 (23%)
Query: 118 PAPSP---------LSAAAVSPSKLPEDDEPPARPPPPPPASVSP--------QAEPVWT 160
PAP P +S V P +EP P P P+ SP EP+
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAE 4943
Query: 161 PPAPAPAAPPSTP--AAPKRR 179
PP P+P S+P A PK R
Sbjct: 4944 PPVPSPLPLASSPESARPKPR 4964
Score = 32.7 bits (73), Expect = 2.1
Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 14/106 (13%)
Query: 87 PPAPRGPL-PAAPPVAPER-----QPSWDPSPVSSTVPAPSPLSAAAVSPSKLPED-DEP 139
P + PL P A V P+ +P +P P + P+P P P + +P
Sbjct: 2324 PDVFKAPLTPRASQVEPQSPGLGLRPQ-EPPPAQALAPSP-PSHPDIFRPGSYTDPYAQP 2381
Query: 140 PARPPPPPPASVSPQAEPVWTPPAPAPAAPPS-TPAAPKRRGSSGS 184
P P P PP P PP P+ P S PA+P+ + SS S
Sbjct: 2382 PLTPRPQPP----PPESCCALPPRSLPSDPFSRVPASPQSQSSSQS 2423
Score = 31.6 bits (70), Expect = 4.7
Identities = 27/112 (24%), Positives = 42/112 (37%), Gaps = 6/112 (5%)
Query: 68 VPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAA 127
+PT P + L+ N PP P LP PP + +++ +P P ++A
Sbjct: 4600 LPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASAR 4659
Query: 128 VSPSKLPEDDEP------PARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTP 173
S L + E A P PP + + E +P P S+P
Sbjct: 4660 DSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSP 4711
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 65.1 bits (157), Expect = 4e-10
Identities = 45/129 (34%), Positives = 59/129 (45%), Gaps = 17/129 (13%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMD-FGNDFVPPAP-RGPLPAAPPVAPERQPSWDPSPVSST 116
P +A P PT P A F ++PP+P P+P PP P++Q P S
Sbjct: 796 PVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPL 855
Query: 117 VPAPSPLSAAAVSPSKLPEDDEPPA---RPPPPPPASVSPQ------AEPVWTP---PAP 164
P PS + A S+ P PPA +P P PA+V+PQ A+P W P P P
Sbjct: 856 SPVPSVVKQIA---SQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVP 912
Query: 165 APAAPPSTP 173
+P PP P
Sbjct: 913 SPDFPPPPP 921
Score = 50.8 bits (120), Expect = 7e-06
Identities = 48/162 (29%), Positives = 66/162 (40%), Gaps = 33/162 (20%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVP 118
P L P PT+ AP++ PP P P+P A ++QP++ P S P
Sbjct: 778 PPKPLVTIPAPTSTKTVAPVV---TQAAPPTPTPPVPPA-----KKQPAF---PASYIPP 826
Query: 119 APSPLSAAAVSPSKLPEDDEPPARPPPPPPAS--------VSPQAEPVWTPPA------- 163
+P P V P LP+ A+PPP P S ++ Q P TPPA
Sbjct: 827 SP-PTPPVPVPPPTLPKQQSFCAKPPPSP-LSPVPSVVKQIASQFPPPPTPPAMESQPLK 884
Query: 164 -----PAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEPVI 200
AP +PP+ A PK + SS V F P ++
Sbjct: 885 PVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLV 926
Score = 48.9 bits (115), Expect = 3e-05
Identities = 37/125 (29%), Positives = 48/125 (38%), Gaps = 21/125 (16%)
Query: 61 AGLSAAP-VPTAPAAGAP-------LMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSP 112
A L AP P+ P AP + PP P P P P+ P+ +P
Sbjct: 726 AQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQ-------AP 778
Query: 113 VSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAP----APAA 168
V P+P S V+P + PP PP PPA P + PP+P P
Sbjct: 779 PKPLVTIPAPTSTKTVAP--VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVP 836
Query: 169 PPSTP 173
PP+ P
Sbjct: 837 PPTLP 841
Score = 43.5 bits (101), Expect = 0.001
Identities = 70/287 (24%), Positives = 104/287 (36%), Gaps = 58/287 (20%)
Query: 55 LERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVS 114
++ KP S+ PVP+ DF PP P L PP PS P+P
Sbjct: 898 VKAKPKWQPSSIPVPSP------------DFPPPPPESSLVFPPP-----PPSPVPAPPP 940
Query: 115 STVPAPSPLSAAAVSP-SKLPEDDEPPARPPPPPP--------ASVSPQAEP-------- 157
P SP + SP K + P + PPP P +S + EP
Sbjct: 941 PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL 1000
Query: 158 --VWTPPAPAPA------APPSTPAAPKRRGSSG-SVDETLFALPAASEPVIRSSAENMD 208
+TPPA + + PP+ P P + SG ++ L +++ + S
Sbjct: 1001 VSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDS 1060
Query: 209 LKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEGTLQEN 268
+ E P DFP ET LP + + S GN S P +
Sbjct: 1061 VVEFPS---PPSDSDFPPPPPETELPLPPIEIPAVFS-------GNTS---PKVAVVNPQ 1107
Query: 269 VSEASKEVSEKA--KTLLIDRDLTEFSELEYSEMGSSFSVSPKAESA 313
+ SK +KA T D T ++ E SE + +V P+ ++
Sbjct: 1108 PQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154
Score = 42.0 bits (97), Expect = 0.003
Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 112 PVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPS 171
P +S VP SP V+P + P PPPPPP P P PP P+ +AP +
Sbjct: 601 PYTSLVPPLSP-QPKIVTPYTASQPSPP--LPPPPPPPPPPPPPPPPPPPPLPSQSAPSA 657
Query: 172 TPAAP 176
AAP
Sbjct: 658 GSAAP 662
Score = 41.6 bits (96), Expect = 0.005
Identities = 29/96 (30%), Positives = 37/96 (38%), Gaps = 6/96 (6%)
Query: 86 VPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPP 145
+PP P P P PP P P S S+ AP + + ++ + PP
Sbjct: 628 LPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPP 687
Query: 146 PPPA----SVSPQ--AEPVWTPPAPAPAAPPSTPAA 175
PP SV PQ P P P P PP TP +
Sbjct: 688 TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGS 723
Score = 41.2 bits (95), Expect = 0.006
Identities = 32/95 (33%), Positives = 38/95 (40%), Gaps = 9/95 (9%)
Query: 87 PPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPP 146
PP P P P + + P P S P P + P P PPPP
Sbjct: 713 PPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAP----PTPPPPPP 768
Query: 147 PPASVSPQA--EPVWTPPAPA---PAAPPSTPAAP 176
PA + PQA +P+ T PAP AP T AAP
Sbjct: 769 IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAP 803
Score = 39.3 bits (90), Expect = 0.023
Identities = 32/109 (29%), Positives = 43/109 (39%), Gaps = 25/109 (22%)
Query: 87 PPAPRGPLPAAPPVAPERQPS-WDPSPVS---STV----------------PAPSPLSAA 126
PP P P P PP+ + PS +P+ ST+ P P + +
Sbjct: 636 PPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQ 695
Query: 127 AVSPSKLPEDD----EPPARPPPPPPASVSPQAEPV-WTPPAPAPAAPP 170
+V P L + PP PPPP P S Q +P P P +APP
Sbjct: 696 SVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPP 744
Score = 32.3 bits (72), Expect = 2.8
Identities = 55/239 (23%), Positives = 83/239 (34%), Gaps = 31/239 (12%)
Query: 592 PAAQLCPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLE-ASSVNYESIK 650
P A+ P+F S PSP P + + P +P + +P SPL SV +
Sbjct: 811 PPAKKQPAFPASYIPPSPPTPPVPVPPP---TLPKQQSFCAKPPPSPLSPVPSVVKQIAS 867
Query: 651 HEPENPPPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAE 710
P PPP AM + + +P N A Q A + +
Sbjct: 868 QFP--PPPTPPAM----------ESQPLKPVPANVAPQSPPA----VKAKPKWQPSSIPV 911
Query: 711 PAPDFSDYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKES 770
P+PDF P P S LV P S PV P D++ K++
Sbjct: 912 PSPDF----------PPPPPESSLVFPPPPPS-PVPAPPPPPPPTASPTPDKSGSPGKKT 960
Query: 771 LTETSFESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIP 829
+S ++ S++ G + E + S+D+ P S KE +P
Sbjct: 961 SKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLP 1019
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 64.7 bits (156), Expect = 5e-10
Identities = 61/214 (28%), Positives = 84/214 (39%), Gaps = 37/214 (17%)
Query: 59 PAAGLSAAPVPTAPAA---------GAPLMDFGNDFVPPAPRGPLPAAPPVAP------- 102
P+A S +P+ PA G+P + + F+P P PL PP AP
Sbjct: 345 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 404
Query: 103 -ERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPAS--VSPQAEPVW 159
+ PS SP S + PSP + A++ L PP PP P S SP P
Sbjct: 405 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 464
Query: 160 TPPAPAPAA--------PPSTPAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKE 211
TPP+ AP + PPS PA+P S+ P A P+ +A + L +
Sbjct: 465 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP-------PQAPPPL---AAPPLQLAK 514
Query: 212 QPGNTISAGQEDFPSVLLETAASLPSLSPLSAAS 245
P A L AS P +P S ++
Sbjct: 515 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 548
Score = 53.1 bits (126), Expect = 2e-06
Identities = 51/158 (32%), Positives = 67/158 (42%), Gaps = 25/158 (15%)
Query: 59 PAAG-LSAAPVPTAPAAGAPLMDFGNDFVPPAPRG---------PLPAAPPVAPERQPSW 108
PA G LS++P+ T P+ A L +P P PLP APP +P PS
Sbjct: 294 PALGPLSSSPLAT-PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP-SPSAPPSL 351
Query: 109 DPSPVSSTVPAPSPLSAAAVSP------SKLPEDDEPPARPPPP--PPASVSPQAEPVWT 160
P P PS + + SP S LP P PPP PPA P P+
Sbjct: 352 QTLPSPPATP-PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP---PLQA 407
Query: 161 PPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEP 198
PP+P PA+PP +P A + ++ L P + P
Sbjct: 408 PPSP-PASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 444
Score = 52.8 bits (125), Expect = 2e-06
Identities = 64/245 (26%), Positives = 90/245 (36%), Gaps = 35/245 (14%)
Query: 17 PRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAG----------LSAA 66
PRP P+ + + P E + E E R+P+AG LS++
Sbjct: 190 PRPAPSARPR----PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 67 PVP-TAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSA 125
P ++PA P P AP P P +P P PA PLS+
Sbjct: 246 ATPLSSPARSGP----SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
Query: 126 ---AAVSPSKLPEDDEPPARPPPPPPASVSPQ-AEPVWTPPAPAPAAPPSTPAAPKRRGS 181
A SPS + PP P P +S++ Q A P+ P P+P+APPS P +
Sbjct: 302 SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP-PSPSAPPSLQTLPSPPAT 360
Query: 182 SGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVL----LETAASLPS 237
S T P A + L P + ++ P L L+ S P+
Sbjct: 361 PPSQATTSLGSPTL-------QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 413
Query: 238 LSPLS 242
PLS
Sbjct: 414 SPPLS 418
Score = 52.8 bits (125), Expect = 2e-06
Identities = 46/147 (31%), Positives = 59/147 (40%), Gaps = 13/147 (8%)
Query: 65 AAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLS 124
A P P AP A A + PP+P P +PP +P PS P + A PL
Sbjct: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 480
Query: 125 AAAVSPSKLPEDDEPPARPPP--PPP--------ASVSPQAEP-VWTPPAPAPAAPPSTP 173
P+ P P A PPP PPP A PQA P + TPP A +PP++
Sbjct: 481 VPPSPPASPPMS--PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 538
Query: 174 AAPKRRGSSGSVDETLFALPAASEPVI 200
S S+ + A P P +
Sbjct: 539 PGQAPFSPSASLPMSPLATPPPQAPPV 565
Score = 51.2 bits (121), Expect = 6e-06
Identities = 49/167 (29%), Positives = 67/167 (40%), Gaps = 15/167 (8%)
Query: 63 LSAAP--VPTAPAAGAPLMDFGNDFVPPAPRGPLP-AAPPVAPERQPSWDPSPVSSTVPA 119
L+A P VP +P A P+ + P P+ P P AAPP+ + P P P +T P
Sbjct: 474 LAAPPLQVPPSPPASPPM----SPSATPPPQAPPPLAAPPLQLAKPPPQAP-PALATPPL 528
Query: 120 PSPLSAAAVSPSKLPEDDE------PPARPPPP-PPASVSPQAEPVWTPPAPAPAAPPST 172
+ S A P + P P A PPP PP +P + +PPA P
Sbjct: 529 QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 588
Query: 173 PAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISA 219
P P S TL P P RS + + + G++ SA
Sbjct: 589 PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 635
Score = 40.4 bits (93), Expect = 0.010
Identities = 41/149 (27%), Positives = 57/149 (38%), Gaps = 37/149 (24%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPV-APERQPSWDPSPVSST- 116
P+A L +P+ T P P++ VPP+P PA+P + AP R P+ P P +S
Sbjct: 546 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSP----PASPTLQAPRRPPT--PGPDTSVS 599
Query: 117 --------VPAPSP------------------LSAAAVSPSKLPEDDEPP---ARPPPPP 147
P P P S+A +P +L D P A PPP
Sbjct: 600 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 659
Query: 148 PASVSPQAEPVWTPPAPAPAAPPSTPAAP 176
A ++ W+ P A P AP
Sbjct: 660 DAELAACHPAAWSRGPAPPLAFRGAPGAP 688
Score = 38.9 bits (89), Expect = 0.029
Identities = 47/171 (27%), Positives = 58/171 (33%), Gaps = 33/171 (19%)
Query: 57 RKP----AAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSP 112
RKP A G+ A +P + P G PA R P AP + + P P
Sbjct: 55 RKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNT-SPGP 113
Query: 113 VSSTVPA-----PSPLSA----------------------AAVSPSKLPEDDEPPARPPP 145
VSS A P PL +A+S + P P
Sbjct: 114 VSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS 173
Query: 146 PPPASVSPQAEPVWTPPAPAPAAPPSTPA-APKRRGSSGSVDETLFALPAA 195
P A S A P PAP+A P P P++ SS S T PAA
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 224
Score = 31.2 bits (69), Expect = 6.1
Identities = 24/83 (28%), Positives = 30/83 (36%), Gaps = 9/83 (10%)
Query: 50 EELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPP-----APRGPLPAAPPVAPER 104
EEL + P G +A+P P A A + PP AP PLP P P
Sbjct: 640 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 699
Query: 105 QPS----WDPSPVSSTVPAPSPL 123
++ S PAP L
Sbjct: 700 ADGLCTIYETEGPESATPAPGAL 722
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 64.7 bits (156), Expect = 5e-10
Identities = 61/214 (28%), Positives = 84/214 (39%), Gaps = 37/214 (17%)
Query: 59 PAAGLSAAPVPTAPAA---------GAPLMDFGNDFVPPAPRGPLPAAPPVAP------- 102
P+A S +P+ PA G+P + + F+P P PL PP AP
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365
Query: 103 -ERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPAS--VSPQAEPVW 159
+ PS SP S + PSP + A++ L PP PP P S SP P
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 425
Query: 160 TPPAPAPAA--------PPSTPAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKE 211
TPP+ AP + PPS PA+P S+ P A P+ +A + L +
Sbjct: 426 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP-------PQAPPPL---AAPPLQLAK 475
Query: 212 QPGNTISAGQEDFPSVLLETAASLPSLSPLSAAS 245
P A L AS P +P S ++
Sbjct: 476 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509
Score = 52.8 bits (125), Expect = 2e-06
Identities = 46/147 (31%), Positives = 59/147 (40%), Gaps = 13/147 (8%)
Query: 65 AAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLS 124
A P P AP A A + PP+P P +PP +P PS P + A PL
Sbjct: 382 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441
Query: 125 AAAVSPSKLPEDDEPPARPPP--PPP--------ASVSPQAEP-VWTPPAPAPAAPPSTP 173
P+ P P A PPP PPP A PQA P + TPP A +PP++
Sbjct: 442 VPPSPPASPPMS--PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 499
Query: 174 AAPKRRGSSGSVDETLFALPAASEPVI 200
S S+ + A P P +
Sbjct: 500 PGQAPFSPSASLPMSPLATPPPQAPPV 526
Score = 52.0 bits (123), Expect = 3e-06
Identities = 52/200 (26%), Positives = 71/200 (35%), Gaps = 44/200 (22%)
Query: 17 PRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAG----------LSAA 66
PRP P+ + + P E + E E R+P+AG LS++
Sbjct: 181 PRPAPSARPR----PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 236
Query: 67 PVPTAPAAGAPLMDFGNDFVPPAPRGPLPAA------PPVAPERQPSWDPSPVSSTVPAP 120
P + A + G P P P P P V P R+ + S+ P
Sbjct: 237 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 296
Query: 121 SPLSAAAVSPSKLPEDDEPPARPPPPPPASV----------------SPQAEPVWTPPAP 164
+P +A SPS P P+ P PP + SP P+ TPP
Sbjct: 297 TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 356
Query: 165 AP--------AAPPSTPAAP 176
AP APPS PA+P
Sbjct: 357 APPALALPPLQAPPSPPASP 376
Score = 51.2 bits (121), Expect = 6e-06
Identities = 49/167 (29%), Positives = 67/167 (40%), Gaps = 15/167 (8%)
Query: 63 LSAAP--VPTAPAAGAPLMDFGNDFVPPAPRGPLP-AAPPVAPERQPSWDPSPVSSTVPA 119
L+A P VP +P A P+ + P P+ P P AAPP+ + P P P +T P
Sbjct: 435 LAAPPLQVPPSPPASPPM----SPSATPPPQAPPPLAAPPLQLAKPPPQAP-PALATPPL 489
Query: 120 PSPLSAAAVSPSKLPEDDE------PPARPPPP-PPASVSPQAEPVWTPPAPAPAAPPST 172
+ S A P + P P A PPP PP +P + +PPA P
Sbjct: 490 QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 549
Query: 173 PAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISA 219
P P S TL P P RS + + + G++ SA
Sbjct: 550 PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 596
Score = 40.4 bits (93), Expect = 0.010
Identities = 41/149 (27%), Positives = 57/149 (38%), Gaps = 37/149 (24%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPV-APERQPSWDPSPVSST- 116
P+A L +P+ T P P++ VPP+P PA+P + AP R P+ P P +S
Sbjct: 507 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSP----PASPTLQAPRRPPT--PGPDTSVS 560
Query: 117 --------VPAPSP------------------LSAAAVSPSKLPEDDEPP---ARPPPPP 147
P P P S+A +P +L D P A PPP
Sbjct: 561 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 620
Query: 148 PASVSPQAEPVWTPPAPAPAAPPSTPAAP 176
A ++ W+ P A P AP
Sbjct: 621 DAELAACHPAAWSRGPAPPLAFRGAPGAP 649
Score = 31.6 bits (70), Expect = 4.7
Identities = 50/172 (29%), Positives = 60/172 (34%), Gaps = 44/172 (25%)
Query: 57 RKP----AAGLSAAPVP-TAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPS 111
RKP A G+ A +P +AP AG PPA G APP + P
Sbjct: 55 RKPLAERAGGIGGATIPESAPRAGPTRTSR-----PPAS-GRGERAPPAK-----NTSPG 103
Query: 112 PVSSTVPA-----PSPLSA----------------------AAVSPSKLPEDDEPPARPP 144
PVSS A P PL +A+S + P P
Sbjct: 104 PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 163
Query: 145 PPPPASVSPQAEPVWTPPAPAPAAPPSTPA-APKRRGSSGSVDETLFALPAA 195
P A S A P PAP+A P P P++ SS S T PAA
Sbjct: 164 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 215
Score = 31.2 bits (69), Expect = 6.1
Identities = 24/83 (28%), Positives = 30/83 (36%), Gaps = 9/83 (10%)
Query: 50 EELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPP-----APRGPLPAAPPVAPER 104
EEL + P G +A+P P A A + PP AP PLP P P
Sbjct: 601 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 660
Query: 105 QPS----WDPSPVSSTVPAPSPL 123
++ S PAP L
Sbjct: 661 ADGLCTIYETEGPESATPAPGAL 683
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 64.7 bits (156), Expect = 5e-10
Identities = 51/161 (31%), Positives = 65/161 (40%), Gaps = 28/161 (17%)
Query: 31 PEDEEEEEEEEEEDEDEDLEELEV--------LERKPAAGLS-AAPVPTAPAAGAPLMDF 81
PE+ E EE E+D+++D ++ E E + G S A+ AP P
Sbjct: 343 PEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402
Query: 82 GNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPA 141
PP P GP P PP AP +P P P + P P P + + P +P P
Sbjct: 403 Q---APPMP-GPPPLGPPPAPPLRP---PGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLP 455
Query: 142 R--PPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG 180
R PP PPP PP P P PP P P RG
Sbjct: 456 RLLPPGPPPGR----------PPGPPPGPPPGLPPGPPPRG 486
Score = 35.8 bits (81), Expect = 0.25
Identities = 35/119 (29%), Positives = 48/119 (40%), Gaps = 10/119 (8%)
Query: 39 EEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAP 98
E+E D ++L +LEV + A LS A + +P AP L
Sbjct: 97 EKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDI 156
Query: 99 PVAPERQPSWDPSPVSSTVPAPSPLSAAAVSP------SKLPEDDEPPARPPPPPPASV 151
P+ P QP PS + T P A ++ P +LP +PP PP PPP V
Sbjct: 157 PL-PGAQP---PSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQV 211
Score = 33.5 bits (75), Expect = 1.2
Identities = 44/172 (25%), Positives = 58/172 (33%), Gaps = 28/172 (16%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQ--------PSWDP 110
P G P P P P G P PR P PA P + P R P P
Sbjct: 462 PPPGRPPGPPPGPPPGLPP----GPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGP 517
Query: 111 SPVSSTVPAPSPLSAAAVSPSKLPE----DDEPPARPPPPPPASVSPQAEPVWTPPAPAP 166
+P PAP P +P L + DD A A++S + + + P A
Sbjct: 518 APPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQ-ITNPKAEIT 576
Query: 167 AAPPS----------TPAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMD 208
P+ AAP+R+ S A P S P + S + D
Sbjct: 577 RFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAP-KSGPSVPVSVQTKD 627
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 64.3 bits (155), Expect = 7e-10
Identities = 57/230 (24%), Positives = 92/230 (40%), Gaps = 13/230 (5%)
Query: 39 EEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAP 98
E + +D ++EEL +P++ P++ +P P GP+P+ P
Sbjct: 1007 EGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQS------PTISEGPVPSLP 1060
Query: 99 PVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPV 158
+ P R PS P P S+ +P A P K P P RPPPP P + + P
Sbjct: 1061 -IRPSRAPSRTPGPPSAQ-SSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPP 1118
Query: 159 WTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFALP-----AASEPVIRSSAENMDLKEQP 213
PP P+ + PS A G +G P +A + R+SA + + Q
Sbjct: 1119 QRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQS 1178
Query: 214 GNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLPTEG 263
+ ++ F L+ A+ P S L + + E L ++ +P G
Sbjct: 1179 KTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSG 1228
Score = 36.2 bits (82), Expect = 0.19
Identities = 62/228 (27%), Positives = 76/228 (33%), Gaps = 61/228 (26%)
Query: 62 GLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPS 121
G + P P P A P + PPA R P P AP P P P T P P
Sbjct: 1186 GSTFLPEPLKPQAAFPPQ---SSLPPPAQRLQEPLVPVAAP--MPQSGPQPNLETPPQPP 1240
Query: 122 PLSAAAVS-PSKLPEDD------------EPPARPPP----------PPPASVSPQAEPV 158
P S ++ S PS+ E P + P A +S Q PV
Sbjct: 1241 PRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPV 1300
Query: 159 WTPPAPAPAAPPSTPAAPKRRG-SSGSVDETLFALPAASEPVIRSSAENM---------- 207
P P P P+A + SS S T+ +PA S+ S ENM
Sbjct: 1301 ---PTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQ-----SQENMRSSPNPFITG 1352
Query: 208 --------DLKEQPGNTISAGQED------FPSVLLETAASLPSLSPL 241
D PGN A E+ F T + PSL PL
Sbjct: 1353 LTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPL 1400
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 63.9 bits (154), Expect = 9e-10
Identities = 119/586 (20%), Positives = 230/586 (39%), Gaps = 104/586 (17%)
Query: 8 PLVSSSDSPPRPQP----AFKYQFVREPEDEEEEEEEEEEDEDE-----------DLEEL 52
P+VSS + Q + ++ P +E++E EEEE DE + EEL
Sbjct: 130 PIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDELEEEEIINDENFLGKRPLDSPEAEEL 189
Query: 53 EVLE-------------------RKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGP 93
++ R+P + ++ +P P + D PP+P P
Sbjct: 190 PAMKRPRLLSTKGDTLDVVLLEAREPLSSINTQKIP--PMLSPVHVQDSTDLAPPSPEPP 247
Query: 94 LPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPP--PPASV 151
+ A PVA + P+ P S P +++ +K P+ + PA P P +V
Sbjct: 248 MLA--PVAKSQMPTAKPLETKSFTPKTKTKTSSPGQKTKSPKTAQSPAMVGSPIRSPKTV 305
Query: 152 SPQAEPVWTPPAP-APAAP------PSTPAAPK--RRGSSGSVDETLFALPAASEPV-IR 201
S + + +P +P +P P TP P+ R S ++ E + + +
Sbjct: 306 SKEKKSPGRSKSPKSPKSPKVTTHIPQTPVRPETPNRTPSATLSEKISKETIQVKQIQTP 365
Query: 202 SSAENMDLKEQPGNTISAGQEDFPSV--LLETAASLPSLSPLSAASFKEHEYLGNLST-- 257
A ++ + QP + A + S+ ++ A + P +S E E G++ T
Sbjct: 366 PDAGKLNSENQPKKAVVADKTIEASIDAVIARACAEREPDPFEFSSGSESE--GDIFTSP 423
Query: 258 --------VLPTEGTLQENVSEA-------SKEVSEKAKTLLIDRDLTEFSELEYSEMGS 302
P T N +++ S S + +D + E + +++G+
Sbjct: 424 KRISGPECTTPKASTSANNFTKSGSTPLPLSGGTSSSDNSWTMDASIDEV--VRKAKLGT 481
Query: 303 SFSVSPKAE--SAVIVANPREEIIVKNKDEEEKLVSNNILHN--QQELPTALTKLVKE-- 356
++ P S+ V+ P E + K +E+ KL S+ + ++EL T + K K+
Sbjct: 482 PSNMPPNFPYISSPSVSPPTPEPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQRD 541
Query: 357 ---------------DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKE 401
D+V EK K++ E + + ++EE AD P++ +++K+ ++
Sbjct: 542 REREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEAD--PYK--FKIKEFED 597
Query: 402 -DSDMLAAGGKIESNLESKVDKKCFADSLEQTNHEKDSE-----SSNDDTSFPSTPEGIK 455
D + G + E DKK + ++ +++ E D P+ P +
Sbjct: 598 VDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLP 657
Query: 456 DRSGAYITCAPFNPAATESIATNIFPLLGDPTSENKTDEKKIEEKK 501
+ A +P + ++ ++ P+L + E K K+ E+KK
Sbjct: 658 PKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKK 703
Score = 48.9 bits (115), Expect = 3e-05
Identities = 43/154 (27%), Positives = 65/154 (42%), Gaps = 24/154 (15%)
Query: 29 REPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDF----GND 84
+E E E++E+E E+E + + E E E+ + PV AP+ P + G D
Sbjct: 712 KEKEKEKKEKEREKEKREREKREKEK-EKHKHEKIKVEPVALAPSPVIPRLTLRVGAGQD 770
Query: 85 FVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPP 144
+ + P P A P + +P +P + PAP P+ VSP+ P
Sbjct: 771 KIVISKVVPAPEAKPAPSQNRPK---TPPPAPAPAPGPM---LVSPA------------P 812
Query: 145 PPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKR 178
P P A P P +P PAA ++ AP R
Sbjct: 813 VPLPLLAQAAAGPALLP-SPGPAASGASAKAPVR 845
Score = 47.8 bits (112), Expect = 6e-05
Identities = 37/133 (27%), Positives = 58/133 (43%), Gaps = 6/133 (4%)
Query: 29 REPEDEEEEEEEEEEDEDEDLEELE-VLERKPAAGLSAAPVPTAPAAGAPLMDF----GN 83
++ E E+E++E+E E E + E+ E E+ + PV AP+ P + G
Sbjct: 710 KKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKVEPVALAPSPVIPRLTLRVGAGQ 769
Query: 84 DFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARP 143
D + + P P A P + +P P P + P P +S A V L + PA
Sbjct: 770 DKIVISKVVPAPEAKPAPSQNRPK-TPPPAPAPAPGPMLVSPAPVPLPLLAQAAAGPALL 828
Query: 144 PPPPPASVSPQAE 156
P P PA+ A+
Sbjct: 829 PSPGPAASGASAK 841
Score = 32.7 bits (73), Expect = 2.1
Identities = 49/234 (20%), Positives = 89/234 (38%), Gaps = 30/234 (12%)
Query: 799 YLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQME-ELSTAVYSNDDLFISKEA------ 851
YL S + ++ +P + T ++ ++PL+ + EL ND+ F+ K
Sbjct: 127 YLPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDELEEEEIINDENFLGKRPLDSPEA 186
Query: 852 -------QIRETETFSDSSPIEIIDEFPTLISSKTDSFSKL-----AREYTDLEVSHKSE 899
+ R T D+ + +++ L S T + ++ TDL
Sbjct: 187 EELPAMKRPRLLSTKGDTLDVVLLEAREPLSSINTQKIPPMLSPVHVQDSTDLAPPSPEP 246
Query: 900 IANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNG-SATSKVLLLPPDVSAL 958
AP +P + L K+ PK + K S +K+ +A S ++ P S
Sbjct: 247 PMLAPVAKSQMPTAK---PLETKSFTPKTKTKTSSPGQKTKSPKTAQSPAMVGSPIRSPK 303
Query: 959 ATQAEIESIVKPKVLVKEAEKKL-------PSDTEKEDRSPSAIFSAELSKTSV 1005
E +S + K K+ P E +R+PSA S ++SK ++
Sbjct: 304 TVSKEKKSPGRSKSPKSPKSPKVTTHIPQTPVRPETPNRTPSATLSEKISKETI 357
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 63.5 bits (153), Expect = 1e-09
Identities = 55/172 (31%), Positives = 73/172 (42%), Gaps = 38/172 (22%)
Query: 23 FKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPAAG---LSAAPVPTAPAAGAPLM 79
F+ +F E + EEEEEEE+E+E+E+LEE+E LE A G A P PT P A
Sbjct: 931 FEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPA----- 985
Query: 80 DFGNDFVPPAPRGPLPAAPPVAPE-------RQPSWDPSPVSSTVPAPSPLSAAAVSPSK 132
+PP P P P PE +P + + T P +P A S +
Sbjct: 986 ------LPP-PESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAP--EALPSQGE 1036
Query: 133 LPEDDEPPARPPPP----------PPASVSPQAEPVWTPPAPAPAAPPSTPA 174
+ + E PA PPP PP + + E P PP TPA
Sbjct: 1037 VEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQP----PPETPA 1084
Score = 52.4 bits (124), Expect = 3e-06
Identities = 50/179 (27%), Positives = 66/179 (36%), Gaps = 55/179 (30%)
Query: 5 DQSPLVSSSDSPPR------------PQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEEL 52
++ P+++ S +PP P+PAF + E D E E + +D + E
Sbjct: 735 NEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPE- 793
Query: 53 EVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSP 112
GL P P A P P AP GP A+PPV + +P P+
Sbjct: 794 ---------GLPPLPPPPPSGATPP---------PIAPTGPPTASPPVPAKEEPEELPA- 834
Query: 113 VSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVS---PQAEPVWTPPAPAPAA 168
AP PL PP PPPP P V+ PQ P TP P A
Sbjct: 835 ------APGPLP--------------PPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPA 873
Score = 46.2 bits (108), Expect = 2e-04
Identities = 52/207 (25%), Positives = 72/207 (34%), Gaps = 33/207 (15%)
Query: 30 EPEDEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPA 89
E E+EEEEEEEEEE+E+E+ E+ E E +F +F
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE--------EFEEEF--EE 937
Query: 90 PRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPA 149
G L E + + + + V P PPA PPP P
Sbjct: 938 EEGELEE----EEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPP 993
Query: 150 SVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDL 209
V P+ E P P P + RG+ + ALP+ E
Sbjct: 994 KVQPEPE-----PEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGE------------ 1036
Query: 210 KEQPGNTISAGQEDFPSVLLETAASLP 236
E+ G + +AG P L+E S P
Sbjct: 1037 VEREGESPAAGPP--PQELVEEEPSAP 1061
Score = 40.8 bits (94), Expect = 0.008
Identities = 38/118 (32%), Positives = 45/118 (38%), Gaps = 19/118 (16%)
Query: 59 PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVP 118
P S P PT P P FG R P PA E + S V ++
Sbjct: 738 PILAPSGTPPPTIP----PDETFGG-------RVPRPAFVHYDKE-----EASDVEISLE 781
Query: 119 APSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAP 176
+ S S V P LP PP PPP ++P P +PP PA P PAAP
Sbjct: 782 SDSDDSVVIV-PEGLPPLPPPPPSGATPPP--IAPTGPPTASPPVPAKEEPEELPAAP 836
Score = 36.6 bits (83), Expect = 0.15
Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 14/98 (14%)
Query: 88 PAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARP---- 143
P+PR P PP+A Q ++ ++ S S A V+ + L PP +P
Sbjct: 590 PSPRCP----PPLACALQ-AFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPT 644
Query: 144 -----PPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAP 176
P PPP + SP P + PP P P+ A P
Sbjct: 645 CPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGP 682
Score = 33.9 bits (76), Expect = 0.95
Identities = 29/95 (30%), Positives = 33/95 (34%), Gaps = 22/95 (23%)
Query: 95 PAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPP-------P 147
P PP+ P P+PV APSP A PP PP P P
Sbjct: 633 PRVPPLQPMGPTCPTPAPVPPP-EAPSPFRA-------------PPFHPPGPMPSVGSMP 678
Query: 148 PASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSS 182
A P A P+ P P+A P P G S
Sbjct: 679 SAGPMPSAGPM-PSAGPVPSARPGPPTTANHLGLS 712
Score = 33.5 bits (75), Expect = 1.2
Identities = 50/196 (25%), Positives = 61/196 (31%), Gaps = 67/196 (34%)
Query: 66 APVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPA--PSPL 123
APVP P A +P F PP P + + P P PS P P + VP+ P P
Sbjct: 649 APVPP-PEAPSPFR--APPFHPPGPMPSVGSMPSAGP--MPSAGPMPSAGPVPSARPGPP 703
Query: 124 SAA-----------AVSPSKLPEDDE------------PPARPPP------------PPP 148
+ A +V P LP + P PPP P P
Sbjct: 704 TTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRP 763
Query: 149 ASVS------------------------PQAEPVWTPPAPAPAAPPS-TPAAPKRRGSSG 183
A V P+ P PP P+ A PP P P
Sbjct: 764 AFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPV 823
Query: 184 SVDETLFALPAASEPV 199
E LPAA P+
Sbjct: 824 PAKEEPEELPAAPGPL 839
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 62.4 bits (150), Expect = 2e-09
Identities = 58/202 (28%), Positives = 75/202 (37%), Gaps = 17/202 (8%)
Query: 11 SSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERK---PAAGLSAAP 67
SSS S + E E+EEEE+ L R+ P P
Sbjct: 1036 SSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVP 1095
Query: 68 VPTAPAAGAPLMDFGNDFVPPA-PRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAA 126
VP AG+P+ PA P GP +PP AP R P P PAP+P
Sbjct: 1096 VPER-VAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGP-----PAPAP---- 1145
Query: 127 AVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTP-AAPKRRGSSGSV 185
P + P P PP +VS A V P P PA PP P R + V
Sbjct: 1146 --RPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKAPRGV 1203
Query: 186 DETLFALPAASEPVIRSSAENM 207
+ T+ LP +++S E +
Sbjct: 1204 ERTIRNLPLDHASLVKSWPEEV 1225
Score = 51.2 bits (121), Expect = 6e-06
Identities = 52/220 (23%), Positives = 83/220 (37%), Gaps = 57/220 (25%)
Query: 29 REPEDEEEEEEEEEEDEDEDLEELEVLERKP----------------------------- 59
+E E++EE++EE++EDED EE +K
Sbjct: 970 QESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDS 1029
Query: 60 ----------AAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWD 109
++ S++ ++ ++ + D LP+A P P P
Sbjct: 1030 TSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASP-PPREVPVPT 1088
Query: 110 PSPVSSTVPAP------SPLSAAAVSPSKL--PEDDEPPA---RPPPPPPASVSPQAEPV 158
P+PV VP +PL SP++ P ++ PP+ RPP PP +P P
Sbjct: 1089 PAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPD 1148
Query: 159 WTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEP 198
P +P P PP PK+R + S + +PA P
Sbjct: 1149 ERPSSPIPLLPP-----PKKRRKTVSF-SAIEVVPAPEPP 1182
Score = 42.7 bits (99), Expect = 0.002
Identities = 44/152 (28%), Positives = 58/152 (38%), Gaps = 22/152 (14%)
Query: 37 EEEEEEEDEDEDLEELEVLERKPA-AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGP-L 94
+ EEEEE+ L + P+ +G P APA +F AP G
Sbjct: 509 DTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPA----------NFEDVAPTGSGE 558
Query: 95 PAAPPVAPERQPSWDPSPVSS--TVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPP---- 148
P A +P+ SP SS + + P+ P PP PPPPPP
Sbjct: 559 PGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYL 618
Query: 149 ASVS---PQAEPVW-TPPAPAPAAPPSTPAAP 176
AS+ P +P + PP P PP P P
Sbjct: 619 ASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPP 650
Score = 40.4 bits (93), Expect = 0.010
Identities = 41/168 (24%), Positives = 63/168 (37%), Gaps = 10/168 (5%)
Query: 90 PRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPP--- 146
PR PP AP + + + P S T P S + P + PP PP P
Sbjct: 384 PRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGG 443
Query: 147 -PPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGS-----SGSVDETLFALPAASEPVI 200
SP+ E V T P PA A +PA S S+D + L
Sbjct: 444 GGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKF 503
Query: 201 RSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKE 248
A + + +E+ +++ G D S + + P P + A+F++
Sbjct: 504 SFLASDTE-EEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFED 550
Score = 40.0 bits (92), Expect = 0.013
Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 4/62 (6%)
Query: 87 PPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPP 146
PPAP P PP P P P +++P P A P+ PP PPPP
Sbjct: 595 PPAPTPPQQPPPPPPPPPPPP----PYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPP 650
Query: 147 PP 148
PP
Sbjct: 651 PP 652
Score = 33.1 bits (74), Expect = 1.6
Identities = 45/166 (27%), Positives = 64/166 (38%), Gaps = 35/166 (21%)
Query: 88 PAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPP 147
PA RG LPA P V + + S P PL +S L + +P PP
Sbjct: 1263 PARRG-LPALPAVEDS-----EATETSDEAERPRPL----LSHILLEHNYALAVKPTPPA 1312
Query: 148 PASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDETLFA----LPAASEPVIRSS 203
PA P+ P PAPAA S+PA DE L A + A EP +
Sbjct: 1313 PALRPPE-------PVPAPAALFSSPA-----------DEVLEAPEVVVAEAEEPKPQQL 1354
Query: 204 AENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPLSAASFKEH 249
+ + E+ G +E+ S ++++S L S + H
Sbjct: 1355 QQQREEGEEEGEEEGEEEEEESS---DSSSSSDGEGALRRRSLRSH 1397
Score = 32.7 bits (73), Expect = 2.1
Identities = 18/45 (40%), Positives = 24/45 (53%)
Query: 2 EDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDED 46
E L+ +V + P+PQ + + E E EEE EEEEEE D
Sbjct: 1334 EVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEESSD 1378
Score = 31.6 bits (70), Expect = 4.7
Identities = 26/96 (27%), Positives = 33/96 (34%), Gaps = 17/96 (17%)
Query: 71 APAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSP 130
+P + M+ +D RG P P P++ P P P P P S P
Sbjct: 575 SPCSSGDDMEISDD-----DRGGSPPPAPTPPQQPP---PPPPPPPPPPPYLASLPLGYP 626
Query: 131 SKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAP 166
P PP PPPP + PP P P
Sbjct: 627 PHQPAYLLPPRPDGPPPPE---------YPPPPPPP 653
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 62.0 bits (149), Expect = 3e-09
Identities = 79/275 (28%), Positives = 111/275 (40%), Gaps = 36/275 (13%)
Query: 54 VLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAP--RGPLPAAPP---VAPERQPSW 108
VL PA+ + PVP + A APL + PP + P+P + P +AP P
Sbjct: 281 VLVPVPASAPPSGPVPLSAPAPAPLSVPVS--APPLALIQAPVPPSAPTLVLAPVPTPVL 338
Query: 109 DPSPVSSTVPAPSPLSAAAVSPSKLPEDDEP------PARPPPPPPASVSPQAEPVWTP- 161
P P S+ AP+P S +P+ P P PA P P PA P P++TP
Sbjct: 339 APMPASTPPAAPAPPSVPMPTPT--PSSGPPSTPTLIPAFAPTPVPA---PTPAPIFTPA 393
Query: 162 PAPAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQ 221
P P PAA P+ A P S + PAA P + + + L QPG ++ Q
Sbjct: 394 PTPMPAATPA--AIPTSAPIPASFSLSRVCFPAAQAPAM----QKVPLSFQPGTVLTPSQ 447
Query: 222 EDFPSVLLETAASLPSL-SPLSAASFKEHEYLGNLSTVLPTEGTLQENVSE---ASKEVS 277
P V + PS PLS A+ + + T+ LQ+ AS E+
Sbjct: 448 ---PLVYIPP----PSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELR 500
Query: 278 EKAKTLLIDRDLTEFSELEYSEMGSSFSVSPKAES 312
+ R LT S+L E+ SP +
Sbjct: 501 SYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGST 535
Score = 50.1 bits (118), Expect = 1e-05
Identities = 51/185 (27%), Positives = 71/185 (38%), Gaps = 23/185 (12%)
Query: 65 AAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPA---APPVAPERQPSWDPSPVSSTVPAPS 121
+ P P + P+ + P P P+PA APP P +P VS++V P
Sbjct: 226 SVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPV 285
Query: 122 PLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGS 181
P SA P P P P P SV A P+ AP P + P+ AP
Sbjct: 286 PASA--------PPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAP----- 332
Query: 182 SGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSPL 241
V + A AS P + ++ + P T S+G P+ L+ A P +P
Sbjct: 333 ---VPTPVLAPMPASTPPAAPAPPSVPM---PTPTPSSGPPSTPT-LIPAFAPTPVPAPT 385
Query: 242 SAASF 246
A F
Sbjct: 386 PAPIF 390
Score = 35.4 bits (80), Expect = 0.33
Identities = 26/97 (26%), Positives = 40/97 (41%), Gaps = 11/97 (11%)
Query: 111 SPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAP---- 166
SP+ + + P+P SA+ P +P+ + P P P P S + + PAP+P
Sbjct: 197 SPLPAPICPPAPGSASV--PHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAP 254
Query: 167 -----AAPPSTPAAPKRRGSSGSVDETLFALPAASEP 198
APPS P L +PA++ P
Sbjct: 255 VPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPP 291
Score = 31.6 bits (70), Expect = 4.7
Identities = 50/229 (21%), Positives = 86/229 (37%), Gaps = 23/229 (10%)
Query: 104 RQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPA 163
R P PS ++T PAP + S + A V P +P+ PA
Sbjct: 525 RLPCTSPSGSTTTQPAPDGVPGPLADTSLVTAS------------AKVLPTPQPLL--PA 570
Query: 164 PAPAAPPSTPAAPKRRGSSGSVDETLFALPAASEPVI-RSSAENMDLKEQPGNTIS-AGQ 221
P+ ++ P PA + ++ P S P + R A + E P + S + +
Sbjct: 571 PSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNR 630
Query: 222 EDFPSVLLETAASLPSLSPLSAASFKEHEYLGNLSTVLP-TEGTLQENVSEASKEVSEKA 280
+ P +P L+P+ +S LSTVL ++ T Q + + +
Sbjct: 631 QKLPLPNQRKTPPMPVLTPVHTSS------KALLSTVLSRSQRTTQAAGGNVTSCLGSTS 684
Query: 281 KTLLIDRDLTEFSELEYSEMGSSFSVSPKAESAVIVANPREEIIVKNKD 329
+I ++ + S+ +S + V VANP ++ NKD
Sbjct: 685 SPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKD 733
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.126 0.344
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,609,767
Number of Sequences: 37866
Number of extensions: 2888391
Number of successful extensions: 68873
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1038
Number of HSP's successfully gapped in prelim test: 1939
Number of HSP's that attempted gapping in prelim test: 25678
Number of HSP's gapped (non-prelim): 21309
length of query: 1192
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1078
effective length of database: 13,930,794
effective search space: 15017395932
effective search space used: 15017395932
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.