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Search of human proteins with 24429572
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo
sapiens]
(1826 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa... 3714 0.0
gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens] 3422 0.0
gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] 3380 0.0
gi|30794372 polybromo 1 isoform 1 [Homo sapiens] 81 8e-15
gi|93102371 polybromo 1 isoform 2 [Homo sapiens] 81 8e-15
gi|41281917 polybromo 1 isoform 4 [Homo sapiens] 81 8e-15
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho... 76 3e-13
gi|153791535 general control of amino acid synthesis 5-like 2 [H... 73 2e-12
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 71 8e-12
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ... 67 2e-10
gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ... 67 2e-10
gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ... 67 2e-10
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] 65 6e-10
gi|164419758 bromodomain containing 2 [Homo sapiens] 64 2e-09
gi|4826806 bromodomain containing 2 [Homo sapiens] 64 2e-09
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 64 2e-09
gi|46399200 testis-specific bromodomain protein [Homo sapiens] 63 3e-09
gi|46399198 testis-specific bromodomain protein [Homo sapiens] 63 3e-09
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 62 4e-09
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 62 4e-09
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 62 5e-09
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 62 5e-09
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi... 61 9e-09
gi|11321642 bromodomain containing protein 1 [Homo sapiens] 60 2e-08
gi|119943102 CREB binding protein isoform b [Homo sapiens] 58 7e-08
gi|119943104 CREB binding protein isoform a [Homo sapiens] 58 7e-08
gi|38788260 bromodomain PHD finger transcription factor isoform ... 58 1e-07
gi|38788274 bromodomain PHD finger transcription factor isoform ... 58 1e-07
gi|34996489 pleckstrin homology domain interacting protein [Homo... 58 1e-07
gi|50345997 E1A binding protein p300 [Homo sapiens] 57 1e-07
>gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo
sapiens]
Length = 1826
Score = 3714 bits (9632), Expect = 0.0
Identities = 1826/1826 (100%), Positives = 1826/1826 (100%)
Query: 1 MRPGCDLLLRAAATVTAAIMSDSDSEEDSSGGGPFTLAGILFGNISGAGQLEGESVLDDE 60
MRPGCDLLLRAAATVTAAIMSDSDSEEDSSGGGPFTLAGILFGNISGAGQLEGESVLDDE
Sbjct: 1 MRPGCDLLLRAAATVTAAIMSDSDSEEDSSGGGPFTLAGILFGNISGAGQLEGESVLDDE 60
Query: 61 CKKHLAGLGALGLGSLITELTANEELTGTGGALVNDEGWIRSTEDAVDYSDINEVAEDES 120
CKKHLAGLGALGLGSLITELTANEELTGTGGALVNDEGWIRSTEDAVDYSDINEVAEDES
Sbjct: 61 CKKHLAGLGALGLGSLITELTANEELTGTGGALVNDEGWIRSTEDAVDYSDINEVAEDES 120
Query: 121 QRHQQTMGSLQPLYHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDAITCVSES 180
QRHQQTMGSLQPLYHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDAITCVSES
Sbjct: 121 QRHQQTMGSLQPLYHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDAITCVSES 180
Query: 181 GEDIILPSIIAPSFLASEKVDFSSYSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDAT 240
GEDIILPSIIAPSFLASEKVDFSSYSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDAT
Sbjct: 181 GEDIILPSIIAPSFLASEKVDFSSYSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDAT 240
Query: 241 KLLPSVTELFPEFRPGKVLRFLHLFGPGKNVPSVWRSARRKRKKHRELIQEEQIQEVECS 300
KLLPSVTELFPEFRPGKVLRFLHLFGPGKNVPSVWRSARRKRKKHRELIQEEQIQEVECS
Sbjct: 241 KLLPSVTELFPEFRPGKVLRFLHLFGPGKNVPSVWRSARRKRKKHRELIQEEQIQEVECS 300
Query: 301 VESEVSQKSLWNYDYAPPPPPEQCLADDEITMMVPVESKFSQSTGDVDKVTDTKPRVAEW 360
VESEVSQKSLWNYDYAPPPPPEQCLADDEITMMVPVESKFSQSTGDVDKVTDTKPRVAEW
Sbjct: 301 VESEVSQKSLWNYDYAPPPPPEQCLADDEITMMVPVESKFSQSTGDVDKVTDTKPRVAEW 360
Query: 361 RYGPARLWYDMLGVSEDGSGFDYGFKLRKTQHEPVIKSRMMEEFRKLEESNGTDLLADEN 420
RYGPARLWYDMLGVSEDGSGFDYGFKLRKTQHEPVIKSRMMEEFRKLEESNGTDLLADEN
Sbjct: 361 RYGPARLWYDMLGVSEDGSGFDYGFKLRKTQHEPVIKSRMMEEFRKLEESNGTDLLADEN 420
Query: 421 FLMVTQLHWEDSIIWDGEDIKHKGTKPQGASLAGWLPSIKTRNVMAYNVQQGFAPTLDDD 480
FLMVTQLHWEDSIIWDGEDIKHKGTKPQGASLAGWLPSIKTRNVMAYNVQQGFAPTLDDD
Sbjct: 421 FLMVTQLHWEDSIIWDGEDIKHKGTKPQGASLAGWLPSIKTRNVMAYNVQQGFAPTLDDD 480
Query: 481 KPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLALDPNDENLILEIPDEKEEAT 540
KPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLALDPNDENLILEIPDEKEEAT
Sbjct: 481 KPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLALDPNDENLILEIPDEKEEAT 540
Query: 541 SNSPSKESKKESSLKKSRILLGKTGVIREEPQQNMSQPEVKDPWNLSNDEYYFPKQQGLR 600
SNSPSKESKKESSLKKSRILLGKTGVIREEPQQNMSQPEVKDPWNLSNDEYYFPKQQGLR
Sbjct: 541 SNSPSKESKKESSLKKSRILLGKTGVIREEPQQNMSQPEVKDPWNLSNDEYYFPKQQGLR 600
Query: 601 GTFGGNIIQHSIPAMELWQPFFPTHMGPIKIRQFHRPPLKKYSFGALSQPGPHSVQPLLK 660
GTFGGNIIQHSIPAMELWQPFFPTHMGPIKIRQFHRPPLKKYSFGALSQPGPHSVQPLLK
Sbjct: 601 GTFGGNIIQHSIPAMELWQPFFPTHMGPIKIRQFHRPPLKKYSFGALSQPGPHSVQPLLK 660
Query: 661 HIKKKAKMREQERQASGGGELFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIK 720
HIKKKAKMREQERQASGGGELFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIK
Sbjct: 661 HIKKKAKMREQERQASGGGELFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIK 720
Query: 721 NYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQALENNLFRAPVYLHKMPETD 780
NYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQALENNLFRAPVYLHKMPETD
Sbjct: 721 NYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQALENNLFRAPVYLHKMPETD 780
Query: 781 FLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSRRANMHIRDFLQVFIYRLFWKSKDR 840
FLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSRRANMHIRDFLQVFIYRLFWKSKDR
Sbjct: 781 FLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSRRANMHIRDFLQVFIYRLFWKSKDR 840
Query: 841 PRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAKVS 900
PRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAKVS
Sbjct: 841 PRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAKVS 900
Query: 901 PEQCCAYYSMIAAKQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVHAAPWNTTRAFIAA 960
PEQCCAYYSMIAAKQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVHAAPWNTTRAFIAA
Sbjct: 901 PEQCCAYYSMIAAKQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVHAAPWNTTRAFIAA 960
Query: 961 MKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQAVKKTVTGTDADLRRLSLK 1020
MKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQAVKKTVTGTDADLRRLSLK
Sbjct: 961 MKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQAVKKTVTGTDADLRRLSLK 1020
Query: 1021 NAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQAHSGEGPMSKFARGSRFSVAEHQER 1080
NAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQAHSGEGPMSKFARGSRFSVAEHQER
Sbjct: 1021 NAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQAHSGEGPMSKFARGSRFSVAEHQER 1080
Query: 1081 YKEECQRIFDLQNKVLSSTEVLSTDTDSISAEDSDFEEMGKNIENMLQNKKTSSQLSREW 1140
YKEECQRIFDLQNKVLSSTEVLSTDTDSISAEDSDFEEMGKNIENMLQNKKTSSQLSREW
Sbjct: 1081 YKEECQRIFDLQNKVLSSTEVLSTDTDSISAEDSDFEEMGKNIENMLQNKKTSSQLSREW 1140
Query: 1141 EEQERKELRRMLLVAGSAASGNNHRDDVTASMTSLKSSATGHCLKIYRTFRDEEGKEYVR 1200
EEQERKELRRMLLVAGSAASGNNHRDDVTASMTSLKSSATGHCLKIYRTFRDEEGKEYVR
Sbjct: 1141 EEQERKELRRMLLVAGSAASGNNHRDDVTASMTSLKSSATGHCLKIYRTFRDEEGKEYVR 1200
Query: 1201 CETVRKPAVIDAYVRIRTTKDEKFIQKFALFDEKHREEMRKERRRIQEQLRRLKRNQEKE 1260
CETVRKPAVIDAYVRIRTTKDEKFIQKFALFDEKHREEMRKERRRIQEQLRRLKRNQEKE
Sbjct: 1201 CETVRKPAVIDAYVRIRTTKDEKFIQKFALFDEKHREEMRKERRRIQEQLRRLKRNQEKE 1260
Query: 1261 KLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNVPPSKPVAMTEEQEE 1320
KLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNVPPSKPVAMTEEQEE
Sbjct: 1261 KLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNVPPSKPVAMTEEQEE 1320
Query: 1321 ELEKTVIHNDNEELIKVEGTKIVFGKQLIENVHEVRRKSLVLKFPKQQLPPKKKRRVGTT 1380
ELEKTVIHNDNEELIKVEGTKIVFGKQLIENVHEVRRKSLVLKFPKQQLPPKKKRRVGTT
Sbjct: 1321 ELEKTVIHNDNEELIKVEGTKIVFGKQLIENVHEVRRKSLVLKFPKQQLPPKKKRRVGTT 1380
Query: 1381 VHCDYLNIPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKII 1440
VHCDYLNIPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKII
Sbjct: 1381 VHCDYLNIPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKII 1440
Query: 1441 TRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKL 1500
TRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKL
Sbjct: 1441 TRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKL 1500
Query: 1501 KEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYY 1560
KEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYY
Sbjct: 1501 KEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYY 1560
Query: 1561 KMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICY 1620
KMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICY
Sbjct: 1561 KMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICY 1620
Query: 1621 QTITEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTSQPPDMYDTNTSLSTSRD 1680
QTITEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTSQPPDMYDTNTSLSTSRD
Sbjct: 1621 QTITEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTSQPPDMYDTNTSLSTSRD 1680
Query: 1681 ASVFQDESNLSVLDISTATPEKQMCQGQGRLGEEDSDVDVEGYDDEEEDGKPKPPAPEGG 1740
ASVFQDESNLSVLDISTATPEKQMCQGQGRLGEEDSDVDVEGYDDEEEDGKPKPPAPEGG
Sbjct: 1681 ASVFQDESNLSVLDISTATPEKQMCQGQGRLGEEDSDVDVEGYDDEEEDGKPKPPAPEGG 1740
Query: 1741 DGDLADEEEGTVQQPEASVLYEDLLISEGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDV 1800
DGDLADEEEGTVQQPEASVLYEDLLISEGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDV
Sbjct: 1741 DGDLADEEEGTVQQPEASVLYEDLLISEGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDV 1800
Query: 1801 GYGGIRPKQPFMLQHASGEHKDGHGK 1826
GYGGIRPKQPFMLQHASGEHKDGHGK
Sbjct: 1801 GYGGIRPKQPFMLQHASGEHKDGHGK 1826
>gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens]
Length = 1893
Score = 3422 bits (8874), Expect = 0.0
Identities = 1696/1816 (93%), Positives = 1738/1816 (95%), Gaps = 31/1816 (1%)
Query: 1 MRPGCDLLLRAAATVTAA-IMSDSDSEEDSSGGGPFTLAGILFGNISGAGQLEGESVLDD 59
M PGCDLLLR AAT+TAA IMSD+DS+EDS+GGGPF+LAG LFGNI+GAGQLEGESVLDD
Sbjct: 1 MGPGCDLLLRTAATITAAAIMSDTDSDEDSAGGGPFSLAGFLFGNINGAGQLEGESVLDD 60
Query: 60 ECKKHLAGLGALGLGSLITELTANEELTGTGGALVNDEGWIRSTEDAVDYSDINEVAEDE 119
ECKKHLAGLGALGLGSLITELTANEELTGT GALVNDEGW+RSTEDAVDYSDINEVAEDE
Sbjct: 61 ECKKHLAGLGALGLGSLITELTANEELTGTDGALVNDEGWVRSTEDAVDYSDINEVAEDE 120
Query: 120 SQRHQQTMGSLQPLYHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDAITCVSE 179
S+R+QQTMGSLQPL HSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQD+IT VSE
Sbjct: 121 SRRYQQTMGSLQPLCHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDSITGVSE 180
Query: 180 SGEDIILPSIIAPSFLASEKVDFSSYSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDA 239
+GE IILPSIIAPS LASEKVDFSS SDSESEMGPQEATQAESEDGKLTLPLAGIMQHDA
Sbjct: 181 NGEGIILPSIIAPSSLASEKVDFSSSSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDA 240
Query: 240 TKLLPSVTELFPEFRPGKVLRFLHLFGPGKNVPSVWRSARRKRKK-HRELIQEEQIQEVE 298
TKLLPSVTELFPEFRPGKVLRFL LFGPGKNVPSVWRSARRKRKK HRELIQEEQIQEVE
Sbjct: 241 TKLLPSVTELFPEFRPGKVLRFLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEVE 300
Query: 299 CSVESEVSQKSLWNYDYAPPPPPEQCLADDEITMMVPVESKFSQSTGDVDKVTDTKPRVA 358
CSVESEVSQKSLWNYDYAPPPPPEQCL+DDEITMM PVESKFSQSTGD+DKVTDTKPRVA
Sbjct: 301 CSVESEVSQKSLWNYDYAPPPPPEQCLSDDEITMMAPVESKFSQSTGDIDKVTDTKPRVA 360
Query: 359 EWRYGPARLWYDMLGVSEDGSGFDYGFKLRKTQHEPVIKSRMMEEFRKLEESNGTDLLAD 418
EWRYGPARLWYDMLGV EDGSGFDYGFKLRKT+HEPVIKSRM+EEFRKLEE+NGTDLLAD
Sbjct: 361 EWRYGPARLWYDMLGVPEDGSGFDYGFKLRKTEHEPVIKSRMIEEFRKLEENNGTDLLAD 420
Query: 419 ENFLMVTQLHWEDSIIWDGEDIKHKGTKPQGASLAGWLPSIKTRNVMAYNVQQGFAPTLD 478
ENFLMVTQLHWED IIWDGED+KHKGTKPQ ASLAGWLPS TRN MAYNVQQGFA TLD
Sbjct: 421 ENFLMVTQLHWEDDIIWDGEDVKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFAATLD 480
Query: 479 DDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLALDPNDENLILEIPDEKEE 538
DDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVL LDPNDENLILEIPDEKEE
Sbjct: 481 DDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKEE 540
Query: 539 ATSNSPSKESKKESSLKKSRILLGKTGVIREEPQQNMSQPEVKDPWNLSNDEYYFPKQQG 598
ATSNSPSKESKKESSLKKSRILLGKTGVI+EEPQQNMSQPEVKDPWNLSNDEYY+PKQQG
Sbjct: 541 ATSNSPSKESKKESSLKKSRILLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQG 600
Query: 599 LRGTFGGNIIQHSIPAMELWQPFFPTHMGPIKIRQFHRPPLKKYSFGALSQPGPHSVQPL 658
LRGTFGGNIIQHSIPA+EL QPFFPTHMGPIK+RQFHRPPLKKYSFGALSQPGPHSVQPL
Sbjct: 601 LRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPL 660
Query: 659 LKHIKKKAKMREQERQASGGGELFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATK 718
LKHIKKKAKMREQERQASGGGE+FFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATK
Sbjct: 661 LKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATK 720
Query: 719 IKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQALENNLFRAPVYLHKMPE 778
IKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQA ENNLFRAP+YLHKMPE
Sbjct: 721 IKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPE 780
Query: 779 TDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSRRANMHIRDFLQVFIYRLFWKSK 838
TDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNS+RAN HIRDFLQVFIYRLFWKSK
Sbjct: 781 TDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSK 840
Query: 839 DRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAK 898
DRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRA
Sbjct: 841 DRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAM 900
Query: 899 VSPEQCCAYYSMIAAKQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVHAAPWNTTRAFI 958
VSPEQCCAYYSMIAA+QRLKDAGYGEKSFFAPEEENEEDFQMKIDDEV APWNTTRAFI
Sbjct: 901 VSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFI 960
Query: 959 AAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQAVKKTVTGTDADLRRLS 1018
AAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQ VKKTVTGTDADLRRLS
Sbjct: 961 AAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLS 1020
Query: 1019 LKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQAHSGEGPMSKFARGSRFSVAEHQ 1078
LKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQA SGEGPMSKFARGSRFSVAEHQ
Sbjct: 1021 LKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQ 1080
Query: 1079 ERYKEECQRIFDLQNKVLSSTEVLSTDTDSISAEDSDFEEMGKNIENMLQNKKTSSQLSR 1138
ERYKEECQRIFDLQNKVLSSTEVLSTDTDS SAEDSDFEEMGKNIENMLQNKKTSSQLSR
Sbjct: 1081 ERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSR 1140
Query: 1139 EWEEQERKELRRMLLVAGSAASGNNHRDDVTASMTSLKSSATGHCLKIYRTFRDEEGKEY 1198
E EEQERKEL+RMLL AGSAASGNNHRDD TAS+TSL SSATG CLKIYRTFRDEEGKEY
Sbjct: 1141 EREEQERKELQRMLLAAGSAASGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEY 1200
Query: 1199 VRCETVRKPAVIDAYVRIRTTKDEKFIQKFALFDEKHREEMRKERRRIQEQLRRLKRNQE 1258
VRCETVRKPAVIDAYVRIRTTKDE+FI+KFALFDE+HREEMRKERRRIQEQLRRLKRNQE
Sbjct: 1201 VRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQE 1260
Query: 1259 KEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNVPPSKPVAMTEEQ 1318
KEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTN PPS PVAMTEEQ
Sbjct: 1261 KEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQ 1320
Query: 1319 EEELEKTVIHNDNEELIKVEGTKIVFGKQLIENVHEVRRKSLVLKFPKQQLPPKKKRRVG 1378
EEELEKTVIHNDNEELIKVEGTKIV GKQLIE+ EVRRKSLVLKFPKQQLPPKKKRRVG
Sbjct: 1321 EEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVG 1380
Query: 1379 TTVHCDYLNIPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYK 1438
TTVHCDYLN PHKSIHRRRTDPMVTLSSILESIINDMRDLPNT+PFHTPVNAKVVKDYYK
Sbjct: 1381 TTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYK 1440
Query: 1439 IITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDE 1498
IITRPMDLQTLRENVRK LYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDE
Sbjct: 1441 IITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDE 1500
Query: 1499 KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD 1558
KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD
Sbjct: 1501 KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD 1560
Query: 1559 YYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNI 1618
YYK+IVNP+DLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVN+
Sbjct: 1561 YYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNV 1620
Query: 1619 CYQTITEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTSQPPDMYDTNTSLSTS 1678
CYQT+TEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYT QPPD+YDTNTSLS S
Sbjct: 1621 CYQTLTEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTPQPPDLYDTNTSLSMS 1680
Query: 1679 RDASVFQDESNLSVLDISTATPEKQMCQGQGRLGEEDSDVDVEGYDDEEEDGKPKPPAPE 1738
RDASVFQDESN+SVLDI +ATPEKQ+ Q EG E
Sbjct: 1681 RDASVFQDESNMSVLDIPSATPEKQVTQ--------------EG---------------E 1711
Query: 1739 GGDGDLADEEEGTVQQPEASVLYEDLLISEGEDDEEDAGSDEEGDNPFSAIQLSESGSDS 1798
GDGDLADEEEGTVQQP+ASVLYEDLL+SEGEDDEEDAGSDEEGDNPFSAIQLSESGSDS
Sbjct: 1712 DGDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEEDAGSDEEGDNPFSAIQLSESGSDS 1771
Query: 1799 DVGYGGIRPKQPFMLQ 1814
DVG GGIRPKQP MLQ
Sbjct: 1772 DVGSGGIRPKQPRMLQ 1787
>gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]
Length = 1872
Score = 3380 bits (8765), Expect = 0.0
Identities = 1678/1816 (92%), Positives = 1719/1816 (94%), Gaps = 52/1816 (2%)
Query: 1 MRPGCDLLLRAAATVTAA-IMSDSDSEEDSSGGGPFTLAGILFGNISGAGQLEGESVLDD 59
M PGCDLLLR AAT+TAA IMSD+DS+EDS+GGGPF+LAG LFGNI+GAGQLEGESVLDD
Sbjct: 1 MGPGCDLLLRTAATITAAAIMSDTDSDEDSAGGGPFSLAGFLFGNINGAGQLEGESVLDD 60
Query: 60 ECKKHLAGLGALGLGSLITELTANEELTGTGGALVNDEGWIRSTEDAVDYSDINEVAEDE 119
ECKKHLAGLGALGLGSLITELTANEELTGT GALVNDEGW+RSTEDAVDYSDINEVAEDE
Sbjct: 61 ECKKHLAGLGALGLGSLITELTANEELTGTDGALVNDEGWVRSTEDAVDYSDINEVAEDE 120
Query: 120 SQRHQQTMGSLQPLYHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDAITCVSE 179
S+R+QQTMGSLQPL HSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQD+IT
Sbjct: 121 SRRYQQTMGSLQPLCHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDSIT---- 176
Query: 180 SGEDIILPSIIAPSFLASEKVDFSSYSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDA 239
EKVDFSS SDSESEMGPQEATQAESEDGKLTLPLAGIMQHDA
Sbjct: 177 -----------------GEKVDFSSSSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDA 219
Query: 240 TKLLPSVTELFPEFRPGKVLRFLHLFGPGKNVPSVWRSARRKRKK-HRELIQEEQIQEVE 298
TKLLPSVTELFPEFRPGKVLRFL LFGPGKNVPSVWRSARRKRKK HRELIQEEQIQEVE
Sbjct: 220 TKLLPSVTELFPEFRPGKVLRFLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEVE 279
Query: 299 CSVESEVSQKSLWNYDYAPPPPPEQCLADDEITMMVPVESKFSQSTGDVDKVTDTKPRVA 358
CSVESEVSQKSLWNYDYAPPPPPEQCL+DDEITMM PVESKFSQSTGD+DKVTDTKPRVA
Sbjct: 280 CSVESEVSQKSLWNYDYAPPPPPEQCLSDDEITMMAPVESKFSQSTGDIDKVTDTKPRVA 339
Query: 359 EWRYGPARLWYDMLGVSEDGSGFDYGFKLRKTQHEPVIKSRMMEEFRKLEESNGTDLLAD 418
EWRYGPARLWYDMLGV EDGSGFDYGFKLRKT+HEPVIKSRM+EEFRKLEE+NGTDLLAD
Sbjct: 340 EWRYGPARLWYDMLGVPEDGSGFDYGFKLRKTEHEPVIKSRMIEEFRKLEENNGTDLLAD 399
Query: 419 ENFLMVTQLHWEDSIIWDGEDIKHKGTKPQGASLAGWLPSIKTRNVMAYNVQQGFAPTLD 478
ENFLMVTQLHWED IIWDGED+KHKGTKPQ ASLAGWLPS TRN MAYNVQQGFA TLD
Sbjct: 400 ENFLMVTQLHWEDDIIWDGEDVKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFAATLD 459
Query: 479 DDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLALDPNDENLILEIPDEKEE 538
DDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVL LDPNDENLILEIPDEKEE
Sbjct: 460 DDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKEE 519
Query: 539 ATSNSPSKESKKESSLKKSRILLGKTGVIREEPQQNMSQPEVKDPWNLSNDEYYFPKQQG 598
ATSNSPSKESKKESSLKKSRILLGKTGVI+EEPQQNMSQPEVKDPWNLSNDEYY+PKQQG
Sbjct: 520 ATSNSPSKESKKESSLKKSRILLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQG 579
Query: 599 LRGTFGGNIIQHSIPAMELWQPFFPTHMGPIKIRQFHRPPLKKYSFGALSQPGPHSVQPL 658
LRGTFGGNIIQHSIPA+EL QPFFPTHMGPIK+RQFHRPPLKKYSFGALSQPGPHSVQPL
Sbjct: 580 LRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPL 639
Query: 659 LKHIKKKAKMREQERQASGGGELFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATK 718
LKHIKKKAKMREQERQASGGGE+FFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATK
Sbjct: 640 LKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATK 699
Query: 719 IKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQALENNLFRAPVYLHKMPE 778
IKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQA ENNLFRAP+YLHKMPE
Sbjct: 700 IKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPE 759
Query: 779 TDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSRRANMHIRDFLQVFIYRLFWKSK 838
TDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNS+RAN HIRDFLQVFIYRLFWKSK
Sbjct: 760 TDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSK 819
Query: 839 DRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAK 898
DRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRA
Sbjct: 820 DRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAM 879
Query: 899 VSPEQCCAYYSMIAAKQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVHAAPWNTTRAFI 958
VSPEQCCAYYSMIAA+QRLKDAGYGEKSFFAPEEENEEDFQMKIDDEV APWNTTRAFI
Sbjct: 880 VSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFI 939
Query: 959 AAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQAVKKTVTGTDADLRRLS 1018
AAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQ VKKTVTGTDADLRRLS
Sbjct: 940 AAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLS 999
Query: 1019 LKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQAHSGEGPMSKFARGSRFSVAEHQ 1078
LKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQA SGEGPMSKFARGSRFSVAEHQ
Sbjct: 1000 LKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQ 1059
Query: 1079 ERYKEECQRIFDLQNKVLSSTEVLSTDTDSISAEDSDFEEMGKNIENMLQNKKTSSQLSR 1138
ERYKEECQRIFDLQNKVLSSTEVLSTDTDS SAEDSDFEEMGKNIENMLQNKKTSSQLSR
Sbjct: 1060 ERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSR 1119
Query: 1139 EWEEQERKELRRMLLVAGSAASGNNHRDDVTASMTSLKSSATGHCLKIYRTFRDEEGKEY 1198
E EEQERKEL+RMLL AGSAASGNNHRDD TAS+TSL SSATG CLKIYRTFRDEEGKEY
Sbjct: 1120 EREEQERKELQRMLLAAGSAASGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEY 1179
Query: 1199 VRCETVRKPAVIDAYVRIRTTKDEKFIQKFALFDEKHREEMRKERRRIQEQLRRLKRNQE 1258
VRCETVRKPAVIDAYVRIRTTKDE+FI+KFALFDE+HREEMRKERRRIQEQLRRLKRNQE
Sbjct: 1180 VRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQE 1239
Query: 1259 KEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNVPPSKPVAMTEEQ 1318
KEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTN PPS PVAMTEEQ
Sbjct: 1240 KEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQ 1299
Query: 1319 EEELEKTVIHNDNEELIKVEGTKIVFGKQLIENVHEVRRKSLVLKFPKQQLPPKKKRRVG 1378
EEELEKTVIHNDNEELIKVEGTKIV GKQLIE+ EVRRKSLVLKFPKQQLPPKKKRRVG
Sbjct: 1300 EEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVG 1359
Query: 1379 TTVHCDYLNIPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYK 1438
TTVHCDYLN PHKSIHRRRTDPMVTLSSILESIINDMRDLPNT+PFHTPVNAKVVKDYYK
Sbjct: 1360 TTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYK 1419
Query: 1439 IITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDE 1498
IITRPMDLQTLRENVRK LYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDE
Sbjct: 1420 IITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDE 1479
Query: 1499 KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD 1558
KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD
Sbjct: 1480 KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD 1539
Query: 1559 YYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNI 1618
YYK+IVNP+DLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVN+
Sbjct: 1540 YYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNV 1599
Query: 1619 CYQTITEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTSQPPDMYDTNTSLSTS 1678
CYQT+TEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYT QPPD+YDTNTSLS S
Sbjct: 1600 CYQTLTEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTPQPPDLYDTNTSLSMS 1659
Query: 1679 RDASVFQDESNLSVLDISTATPEKQMCQGQGRLGEEDSDVDVEGYDDEEEDGKPKPPAPE 1738
RDASVFQDESN+SVLDI +ATPEKQ+ Q EG E
Sbjct: 1660 RDASVFQDESNMSVLDIPSATPEKQVTQ--------------EG---------------E 1690
Query: 1739 GGDGDLADEEEGTVQQPEASVLYEDLLISEGEDDEEDAGSDEEGDNPFSAIQLSESGSDS 1798
GDGDLADEEEGTVQQP+ASVLYEDLL+SEGEDDEEDAGSDEEGDNPFSAIQLSESGSDS
Sbjct: 1691 DGDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEEDAGSDEEGDNPFSAIQLSESGSDS 1750
Query: 1799 DVGYGGIRPKQPFMLQ 1814
DVG GGIRPKQP MLQ
Sbjct: 1751 DVGSGGIRPKQPRMLQ 1766
>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
Length = 1602
Score = 81.3 bits (199), Expect = 8e-15
Identities = 61/229 (26%), Positives = 95/229 (41%), Gaps = 45/229 (19%)
Query: 1424 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKH 1483
F + K DYYKII PMDL+ + N+R Y E E ++L+ +N+ YN
Sbjct: 514 FMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGS 573
Query: 1484 SLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPD 1543
+ + + L EK KE + PL DDDD + L ++K P
Sbjct: 574 QVYNDAHILEKLLKEKRKE-----------LGPLPDDDDMASPKLKL----SRKSGISPK 618
Query: 1544 SWPFHHPVNKKF------------------------------VPDYYKMIVNPVDLETIR 1573
+ P+ +K +PDYY I P+D+E IR
Sbjct: 619 KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIR 678
Query: 1574 KNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQT 1622
++ +KYQ +S ++D ++ N+ YN PES K A + + +T
Sbjct: 679 SHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 727
Score = 73.6 bits (179), Expect = 2e-12
Identities = 65/234 (27%), Positives = 105/234 (44%), Gaps = 34/234 (14%)
Query: 1398 TDPMVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCL 1457
++P L + S N+ L +H P + K DYY+ I P+ LQ +R ++
Sbjct: 351 SNPFYQLYDTVRSCRNNQGQLIAEPFYHLP-SKKKYPDYYQQIKMPISLQQIRTKLKNQE 409
Query: 1458 YPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPL 1517
Y + + L L+ +N+ YN P + I + +L L + ++ K+ +LAR +
Sbjct: 410 YETLDHLECDLNLMFENAKRYNVPNSA---IYKRVLKL-QQVMQAKKKELARRDD----- 460
Query: 1518 LDDDDQVAFSFILD----------NIVTQKMMAV---------PDSWP-----FHHPVNK 1553
++D D + S D NI Q+M + P S F +K
Sbjct: 461 IEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSK 520
Query: 1554 KFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1607
K PDYYK+I+ P+DL+ I NI KY E ++D+ L+ N+ YN SQ
Sbjct: 521 KDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQ 574
Score = 69.7 bits (169), Expect = 2e-11
Identities = 60/265 (22%), Positives = 108/265 (40%), Gaps = 21/265 (7%)
Query: 1386 LNIPHKSIHRRRTDPMVTLS--SILESIINDMRDLPNTHP------FHTPVNAKVVKDYY 1437
++ P S RRR + T+ ++ + N +RD + F + DYY
Sbjct: 26 VSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYY 85
Query: 1438 KIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCD 1497
+++++P+DL +++ ++ Y +L+ N+ +Y P + + + DL
Sbjct: 86 EVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYL 145
Query: 1498 EKLKE--------KEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP--- 1546
E ED + + + IL+ ++ ++A S
Sbjct: 146 RTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLIS 205
Query: 1547 --FHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGP 1604
F +K PDYY +I P+DL+TI + I Y+S + D++L+ N+ YN P
Sbjct: 206 ELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEP 265
Query: 1605 ESQYTKTAQEIVNICYQTITEYDEH 1629
SQ K A I I Y E + H
Sbjct: 266 GSQVFKDANSIKKIFYMKKAEIEHH 290
Score = 54.3 bits (129), Expect = 1e-06
Identities = 24/73 (32%), Positives = 41/73 (56%)
Query: 1546 PFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPE 1605
PF+H +KK PDYY+ I P+ L+ IR + +Y++ + D+NL+ N+ +YN P
Sbjct: 375 PFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPN 434
Query: 1606 SQYTKTAQEIVNI 1618
S K ++ +
Sbjct: 435 SAIYKRVLKLQQV 447
>gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
Length = 1582
Score = 81.3 bits (199), Expect = 8e-15
Identities = 61/229 (26%), Positives = 95/229 (41%), Gaps = 45/229 (19%)
Query: 1424 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKH 1483
F + K DYYKII PMDL+ + N+R Y E E ++L+ +N+ YN
Sbjct: 546 FMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGS 605
Query: 1484 SLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPD 1543
+ + + L EK KE + PL DDDD + L ++K P
Sbjct: 606 QVYNDAHILEKLLKEKRKE-----------LGPLPDDDDMASPKLKL----SRKSGISPK 650
Query: 1544 SWPFHHPVNKKF------------------------------VPDYYKMIVNPVDLETIR 1573
+ P+ +K +PDYY I P+D+E IR
Sbjct: 651 KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIR 710
Query: 1574 KNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQT 1622
++ +KYQ +S ++D ++ N+ YN PES K A + + +T
Sbjct: 711 SHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 759
Score = 73.6 bits (179), Expect = 2e-12
Identities = 65/234 (27%), Positives = 105/234 (44%), Gaps = 34/234 (14%)
Query: 1398 TDPMVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCL 1457
++P L + S N+ L +H P + K DYY+ I P+ LQ +R ++
Sbjct: 383 SNPFYQLYDTVRSCRNNQGQLIAEPFYHLP-SKKKYPDYYQQIKMPISLQQIRTKLKNQE 441
Query: 1458 YPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPL 1517
Y + + L L+ +N+ YN P + I + +L L + ++ K+ +LAR +
Sbjct: 442 YETLDHLECDLNLMFENAKRYNVPNSA---IYKRVLKL-QQVMQAKKKELARRDD----- 492
Query: 1518 LDDDDQVAFSFILD----------NIVTQKMMAV---------PDSWP-----FHHPVNK 1553
++D D + S D NI Q+M + P S F +K
Sbjct: 493 IEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSK 552
Query: 1554 KFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1607
K PDYYK+I+ P+DL+ I NI KY E ++D+ L+ N+ YN SQ
Sbjct: 553 KDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQ 606
Score = 69.7 bits (169), Expect = 2e-11
Identities = 60/265 (22%), Positives = 108/265 (40%), Gaps = 21/265 (7%)
Query: 1386 LNIPHKSIHRRRTDPMVTLS--SILESIINDMRDLPNTHP------FHTPVNAKVVKDYY 1437
++ P S RRR + T+ ++ + N +RD + F + DYY
Sbjct: 26 VSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYY 85
Query: 1438 KIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCD 1497
+++++P+DL +++ ++ Y +L+ N+ +Y P + + + DL
Sbjct: 86 EVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYL 145
Query: 1498 EKLKE--------KEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP--- 1546
E ED + + + IL+ ++ ++A S
Sbjct: 146 RTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLIS 205
Query: 1547 --FHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGP 1604
F +K PDYY +I P+DL+TI + I Y+S + D++L+ N+ YN P
Sbjct: 206 ELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEP 265
Query: 1605 ESQYTKTAQEIVNICYQTITEYDEH 1629
SQ K A I I Y E + H
Sbjct: 266 GSQVFKDANSIKKIFYMKKAEIEHH 290
Score = 54.3 bits (129), Expect = 1e-06
Identities = 24/73 (32%), Positives = 41/73 (56%)
Query: 1546 PFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPE 1605
PF+H +KK PDYY+ I P+ L+ IR + +Y++ + D+NL+ N+ +YN P
Sbjct: 407 PFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPN 466
Query: 1606 SQYTKTAQEIVNI 1618
S K ++ +
Sbjct: 467 SAIYKRVLKLQQV 479
>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
Length = 1582
Score = 81.3 bits (199), Expect = 8e-15
Identities = 61/229 (26%), Positives = 95/229 (41%), Gaps = 45/229 (19%)
Query: 1424 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKH 1483
F + K DYYKII PMDL+ + N+R Y E E ++L+ +N+ YN
Sbjct: 546 FMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGS 605
Query: 1484 SLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPD 1543
+ + + L EK KE + PL DDDD + L ++K P
Sbjct: 606 QVYNDAHILEKLLKEKRKE-----------LGPLPDDDDMASPKLKL----SRKSGISPK 650
Query: 1544 SWPFHHPVNKKF------------------------------VPDYYKMIVNPVDLETIR 1573
+ P+ +K +PDYY I P+D+E IR
Sbjct: 651 KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIR 710
Query: 1574 KNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQT 1622
++ +KYQ +S ++D ++ N+ YN PES K A + + +T
Sbjct: 711 SHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLET 759
Score = 73.6 bits (179), Expect = 2e-12
Identities = 65/234 (27%), Positives = 105/234 (44%), Gaps = 34/234 (14%)
Query: 1398 TDPMVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCL 1457
++P L + S N+ L +H P + K DYY+ I P+ LQ +R ++
Sbjct: 383 SNPFYQLYDTVRSCRNNQGQLIAEPFYHLP-SKKKYPDYYQQIKMPISLQQIRTKLKNQE 441
Query: 1458 YPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPL 1517
Y + + L L+ +N+ YN P + I + +L L + ++ K+ +LAR +
Sbjct: 442 YETLDHLECDLNLMFENAKRYNVPNSA---IYKRVLKL-QQVMQAKKKELARRDD----- 492
Query: 1518 LDDDDQVAFSFILD----------NIVTQKMMAV---------PDSWP-----FHHPVNK 1553
++D D + S D NI Q+M + P S F +K
Sbjct: 493 IEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSK 552
Query: 1554 KFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1607
K PDYYK+I+ P+DL+ I NI KY E ++D+ L+ N+ YN SQ
Sbjct: 553 KDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQ 606
Score = 69.7 bits (169), Expect = 2e-11
Identities = 60/265 (22%), Positives = 108/265 (40%), Gaps = 21/265 (7%)
Query: 1386 LNIPHKSIHRRRTDPMVTLS--SILESIINDMRDLPNTHP------FHTPVNAKVVKDYY 1437
++ P S RRR + T+ ++ + N +RD + F + DYY
Sbjct: 26 VSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYY 85
Query: 1438 KIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCD 1497
+++++P+DL +++ ++ Y +L+ N+ +Y P + + + DL
Sbjct: 86 EVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYL 145
Query: 1498 EKLKE--------KEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP--- 1546
E ED + + + IL+ ++ ++A S
Sbjct: 146 RTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLIS 205
Query: 1547 --FHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGP 1604
F +K PDYY +I P+DL+TI + I Y+S + D++L+ N+ YN P
Sbjct: 206 ELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEP 265
Query: 1605 ESQYTKTAQEIVNICYQTITEYDEH 1629
SQ K A I I Y E + H
Sbjct: 266 GSQVFKDANSIKKIFYMKKAEIEHH 290
Score = 54.3 bits (129), Expect = 1e-06
Identities = 24/73 (32%), Positives = 41/73 (56%)
Query: 1546 PFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPE 1605
PF+H +KK PDYY+ I P+ L+ IR + +Y++ + D+NL+ N+ +YN P
Sbjct: 407 PFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPN 466
Query: 1606 SQYTKTAQEIVNI 1618
S K ++ +
Sbjct: 467 SAIYKRVLKLQQV 479
>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
sapiens]
Length = 1484
Score = 75.9 bits (185), Expect = 3e-13
Identities = 38/119 (31%), Positives = 67/119 (56%), Gaps = 6/119 (5%)
Query: 1509 RLEKAINPLLD-DDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKMIVNPV 1567
R EK L + DDD A +LD + K DSWPF PV++ + P+YY++I P+
Sbjct: 425 REEKKTKDLFELDDDFTAMYKVLDVVKAHK-----DSWPFLEPVDESYAPNYYQIIKAPM 479
Query: 1568 DLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITEY 1626
D+ ++ K ++ Y ++E F++D+ + N KYNG S+YTK + + ++ + ++
Sbjct: 480 DISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKH 538
Score = 53.1 bits (126), Expect = 2e-06
Identities = 44/189 (23%), Positives = 92/189 (48%), Gaps = 11/189 (5%)
Query: 1312 VAMTEEQEEELEKTVIHNDNEELIK-VEG---TKIVFGKQLIENVHEV-RRKSLVLKFPK 1366
+A+ ++++E++ K + EE +K VEG ++V+ + V R K L+ +
Sbjct: 342 LAVQKKEQEQMLKEERKRELEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREER 401
Query: 1367 QQLPPKKKRRVGTTVHCDYLNIPHKSIHRRRTDPMVTLS---SILESIINDMRDLPNTHP 1423
L + K H D N P + ++T + L + + +++ ++ ++ P
Sbjct: 402 AWLLAQGKELPPELSHLDP-NSPMRE--EKKTKDLFELDDDFTAMYKVLDVVKAHKDSWP 458
Query: 1424 FHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKH 1483
F PV+ +YY+II PMD+ ++ + + LY ++EEF ++ + +N YNG
Sbjct: 459 FLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESS 518
Query: 1484 SLTQISQSM 1492
T++S ++
Sbjct: 519 EYTKMSDNL 527
>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
sapiens]
Length = 837
Score = 73.2 bits (178), Expect = 2e-12
Identities = 37/108 (34%), Positives = 63/108 (58%), Gaps = 3/108 (2%)
Query: 1518 LDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNIS 1577
L D DQ+ + L N++ Q + + P +WPF PV K PDYY++I P+DL+T+ + +
Sbjct: 727 LKDPDQLYTT--LKNLLAQ-IKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLR 783
Query: 1578 KHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITE 1625
Y +R+ F+ D+ ++AN +YN P+S+Y + A + Y + E
Sbjct: 784 SRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
Score = 57.0 bits (136), Expect = 2e-07
Identities = 29/99 (29%), Positives = 52/99 (52%)
Query: 1404 LSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREE 1463
L + L++++ ++ P+ PF PV DYY++I P+DL+T+ E +R Y +R+
Sbjct: 733 LYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKL 792
Query: 1464 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE 1502
F L+ ++ N YN P + + ++ KLKE
Sbjct: 793 FVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 71.2 bits (173), Expect = 8e-12
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 14/160 (8%)
Query: 1530 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESF 1587
+ N+V + + +WPF+ PV+ K +PDY+K+I NP+D+ TI+K + + Y S
Sbjct: 42 MQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASEC 101
Query: 1588 LDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITEYDEHLTQL---------EKDIC 1638
+ D N + N YN P AQ + I Q + + + +L K
Sbjct: 102 MQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAA 161
Query: 1639 TAKEAALEE-AELESLDPMTPGPYTSQPPDMYDTNTSLST 1677
A+ A ++ A + S+ P T P+ S PP + T +T
Sbjct: 162 GAQSAGTQQVAAVSSVSPAT--PFQSVPPTVSQTPVIAAT 199
Score = 58.2 bits (139), Expect = 7e-08
Identities = 47/216 (21%), Positives = 97/216 (44%), Gaps = 10/216 (4%)
Query: 1529 ILDNIVTQKMMAVPDSWPFHHPVNKKFVP--DYYKMIVNPVDLETIRKNISKHKYQSRES 1586
IL ++++K A +WPF+ PV+ + + DY+ +I +P+DL T+++ + +Y +
Sbjct: 318 ILREMLSKKHAAY--AWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQG 375
Query: 1587 FLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITEYDEHLTQLEKDICTAKEAALE 1646
F DV L+ +N KYN P+ + A+++ ++ + + +E A A +
Sbjct: 376 FAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE--PVEAPALPAPAAPMV 433
Query: 1647 EAELESLDPMTPGPYTSQPPDMYDTN-TSLSTSRDASVFQDESNLSVLDISTATPEKQMC 1705
ES S D + T L+ ++ E ++ P+K+
Sbjct: 434 SKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKE 493
Query: 1706 QGQGRLGEEDSDVDVEGYD---DEEEDGKPKPPAPE 1738
+ + ++D + + E + +EE+ K PPA +
Sbjct: 494 KKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQ 529
Score = 52.8 bits (125), Expect = 3e-06
Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Query: 1423 PFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNG 1480
PF+ PV+A+ ++ DY+ II PMDL T++ + YP + F + L+ N YN
Sbjct: 333 PFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNP 392
Query: 1481 PKHSLTQISQSMLDLCDEKLKEKEDK 1506
P H + +++ + D+ + + + D+
Sbjct: 393 PDHEVVAMARKLQDVFEMRFAKMPDE 418
Score = 43.5 bits (101), Expect = 0.002
Identities = 23/82 (28%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Query: 1423 PFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNG 1480
PF+ PV+A + DY+KII PMD+ T+++ + Y S E + + N YN
Sbjct: 58 PFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNK 117
Query: 1481 PKHSLTQISQSMLDLCDEKLKE 1502
P + ++Q++ + +K+ +
Sbjct: 118 PTDDIVLMAQALEKIFLQKVAQ 139
>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
sapiens]
Length = 1135
Score = 67.0 bits (162), Expect = 2e-10
Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Query: 1404 LSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREE 1463
LS +L+ I M+ P T F PV + DY + I PMDL TL +N +K +Y E
Sbjct: 149 LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 207
Query: 1464 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1504
F + I+ N YNG H LTQI++ ++ +C+ ++ E E
Sbjct: 208 FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 248
Score = 60.8 bits (146), Expect = 1e-08
Identities = 32/89 (35%), Positives = 47/89 (52%)
Query: 1539 MAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANS 1598
M P + F PV + PDY + I +P+DL T+ KN K Y E+FL D IL N
Sbjct: 160 MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 219
Query: 1599 VKYNGPESQYTKTAQEIVNICYQTITEYD 1627
+ YNG + T+ A+ ++ IC + E +
Sbjct: 220 IIYNGGNHKLTQIAKVVIKICEHEMNEIE 248
>gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
sapiens]
Length = 1188
Score = 67.0 bits (162), Expect = 2e-10
Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Query: 1404 LSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREE 1463
LS +L+ I M+ P T F PV + DY + I PMDL TL +N +K +Y E
Sbjct: 174 LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 232
Query: 1464 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1504
F + I+ N YNG H LTQI++ ++ +C+ ++ E E
Sbjct: 233 FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
Score = 60.8 bits (146), Expect = 1e-08
Identities = 32/89 (35%), Positives = 47/89 (52%)
Query: 1539 MAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANS 1598
M P + F PV + PDY + I +P+DL T+ KN K Y E+FL D IL N
Sbjct: 185 MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 244
Query: 1599 VKYNGPESQYTKTAQEIVNICYQTITEYD 1627
+ YNG + T+ A+ ++ IC + E +
Sbjct: 245 IIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
>gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
sapiens]
Length = 1160
Score = 67.0 bits (162), Expect = 2e-10
Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Query: 1404 LSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREE 1463
LS +L+ I M+ P T F PV + DY + I PMDL TL +N +K +Y E
Sbjct: 174 LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 232
Query: 1464 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1504
F + I+ N YNG H LTQI++ ++ +C+ ++ E E
Sbjct: 233 FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
Score = 60.8 bits (146), Expect = 1e-08
Identities = 32/89 (35%), Positives = 47/89 (52%)
Query: 1539 MAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANS 1598
M P + F PV + PDY + I +P+DL T+ KN K Y E+FL D IL N
Sbjct: 185 MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 244
Query: 1599 VKYNGPESQYTKTAQEIVNICYQTITEYD 1627
+ YNG + T+ A+ ++ IC + E +
Sbjct: 245 IIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
Length = 832
Score = 65.1 bits (157), Expect = 6e-10
Identities = 29/92 (31%), Positives = 51/92 (55%)
Query: 1534 VTQKMMAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNL 1593
+ Q++ + +WPF PV + P YY++I P+DL+T+ + + Y S++ F+ D+
Sbjct: 735 ILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQR 794
Query: 1594 ILANSVKYNGPESQYTKTAQEIVNICYQTITE 1625
+ N +YN PES+Y K A + + I E
Sbjct: 795 VFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
Score = 53.9 bits (128), Expect = 1e-06
Identities = 29/99 (29%), Positives = 49/99 (49%)
Query: 1404 LSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREE 1463
L S L+SI+ ++ + PF PV YY++I PMDL+T+ E ++ Y S++
Sbjct: 728 LYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKL 787
Query: 1464 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE 1502
F L+ + N YN P+ + + + K+KE
Sbjct: 788 FMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 63.5 bits (153), Expect = 2e-09
Identities = 108/508 (21%), Positives = 190/508 (37%), Gaps = 104/508 (20%)
Query: 1312 VAMTEEQEEELEKTVIHNDNEELIKVEGTKIVFGKQLIENVHEVRRKSLVLKFPKQQLPP 1371
VA ++E+EL T+ N +++ G K+ + + + H+V S V PP
Sbjct: 177 VASMPQEEQELVVTIPKNSHKK-----GAKLAALQGSVTSAHQVPAVSSVSHTALYTPPP 231
Query: 1372 KKKRRVGTTVHCDYLNIPHKSIHRRRTDPMVTLSSILESIINDMRDL------PNTHPFH 1425
+ + TTV LNIPH P V S +L+S+ + L P P
Sbjct: 232 E----IPTTV----LNIPH---------PSVISSPLLKSLHSAGPPLLAVTAAPPAQPLA 274
Query: 1426 TPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSL 1485
K D T P L S E L + + S P
Sbjct: 275 KKKGVKRKAD----TTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRK- 329
Query: 1486 TQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSW 1545
DL D + + + K +L + + + IL ++++K A +W
Sbjct: 330 --------DLPDSQQQHQSSKKGKLSEQLKHC---------NGILKELLSKKHAAY--AW 370
Query: 1546 PFHHPVNKKFVP--DYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNG 1603
PF+ PV+ + DY+ +I +P+DL T+++ + Y+ + F DV L+ +N KYN
Sbjct: 371 PFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNP 430
Query: 1604 PESQYTKTAQEIVNICYQTITEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPY-- 1661
P+ A+++ +D+ + A + + +P+ PGP
Sbjct: 431 PDHDVVAMARKL-------------------QDVFEFRYAKMPD------EPLEPGPLPV 465
Query: 1662 -TSQPPDMYDTNTSLSTSRDASVFQDESNLSVLDISTATPEKQMCQGQGRLGEEDSDVDV 1720
T+ PP + +++ S+ +S S++ E++ + E++ + +
Sbjct: 466 STAMPPGLAKSSSESSSEESSSE------------SSSEEEEEEDE------EDEEEEES 507
Query: 1721 EGYDDEEEDGKPKPPAPE---GGDGDLADEEEGTVQQPEAS-VLYEDLLISEGEDDEEDA 1776
E D EEE E LA +G + +P+ E + E A
Sbjct: 508 ESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRA 567
Query: 1777 GSDEEGDNPFSAIQLSESGSDSDVGYGG 1804
G+DE+ P + S G GG
Sbjct: 568 GADEDDKGPRAPRPPQPKKSKKASGSGG 595
Score = 55.8 bits (133), Expect = 4e-07
Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 2/106 (1%)
Query: 1530 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESF 1587
L +V + + +WPF PV+ K +PDY+K+I P+D+ TI++ + + Y +
Sbjct: 82 LHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASEC 141
Query: 1588 LDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITEYDEHLTQL 1633
+ D N + N YN P AQ + I Q + + +L
Sbjct: 142 MQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQEL 187
Score = 41.2 bits (95), Expect = 0.009
Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Query: 1423 PFHTPVNAKVV--KDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNG 1480
PF PV+A + DY+KII +PMD+ T++ + Y + E + + N YN
Sbjct: 98 PFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNK 157
Query: 1481 PKHSLTQISQSM 1492
P + ++Q++
Sbjct: 158 PTDDIVLMAQTL 169
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 63.5 bits (153), Expect = 2e-09
Identities = 108/508 (21%), Positives = 190/508 (37%), Gaps = 104/508 (20%)
Query: 1312 VAMTEEQEEELEKTVIHNDNEELIKVEGTKIVFGKQLIENVHEVRRKSLVLKFPKQQLPP 1371
VA ++E+EL T+ N +++ G K+ + + + H+V S V PP
Sbjct: 177 VASMPQEEQELVVTIPKNSHKK-----GAKLAALQGSVTSAHQVPAVSSVSHTALYTPPP 231
Query: 1372 KKKRRVGTTVHCDYLNIPHKSIHRRRTDPMVTLSSILESIINDMRDL------PNTHPFH 1425
+ + TTV LNIPH P V S +L+S+ + L P P
Sbjct: 232 E----IPTTV----LNIPH---------PSVISSPLLKSLHSAGPPLLAVTAAPPAQPLA 274
Query: 1426 TPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSL 1485
K D T P L S E L + + S P
Sbjct: 275 KKKGVKRKAD----TTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRK- 329
Query: 1486 TQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSW 1545
DL D + + + K +L + + + IL ++++K A +W
Sbjct: 330 --------DLPDSQQQHQSSKKGKLSEQLKHC---------NGILKELLSKKHAAY--AW 370
Query: 1546 PFHHPVNKKFVP--DYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNG 1603
PF+ PV+ + DY+ +I +P+DL T+++ + Y+ + F DV L+ +N KYN
Sbjct: 371 PFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNP 430
Query: 1604 PESQYTKTAQEIVNICYQTITEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPY-- 1661
P+ A+++ +D+ + A + + +P+ PGP
Sbjct: 431 PDHDVVAMARKL-------------------QDVFEFRYAKMPD------EPLEPGPLPV 465
Query: 1662 -TSQPPDMYDTNTSLSTSRDASVFQDESNLSVLDISTATPEKQMCQGQGRLGEEDSDVDV 1720
T+ PP + +++ S+ +S S++ E++ + E++ + +
Sbjct: 466 STAMPPGLAKSSSESSSEESSSE------------SSSEEEEEEDE------EDEEEEES 507
Query: 1721 EGYDDEEEDGKPKPPAPE---GGDGDLADEEEGTVQQPEAS-VLYEDLLISEGEDDEEDA 1776
E D EEE E LA +G + +P+ E + E A
Sbjct: 508 ESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRA 567
Query: 1777 GSDEEGDNPFSAIQLSESGSDSDVGYGG 1804
G+DE+ P + S G GG
Sbjct: 568 GADEDDKGPRAPRPPQPKKSKKASGSGG 595
Score = 55.8 bits (133), Expect = 4e-07
Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 2/106 (1%)
Query: 1530 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESF 1587
L +V + + +WPF PV+ K +PDY+K+I P+D+ TI++ + + Y +
Sbjct: 82 LHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASEC 141
Query: 1588 LDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITEYDEHLTQL 1633
+ D N + N YN P AQ + I Q + + +L
Sbjct: 142 MQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQEL 187
Score = 41.2 bits (95), Expect = 0.009
Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Query: 1423 PFHTPVNAKVV--KDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNG 1480
PF PV+A + DY+KII +PMD+ T++ + Y + E + + N YN
Sbjct: 98 PFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNK 157
Query: 1481 PKHSLTQISQSM 1492
P + ++Q++
Sbjct: 158 PTDDIVLMAQTL 169
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 63.5 bits (153), Expect = 2e-09
Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 14/120 (11%)
Query: 1494 DLCDEKLKE-------KEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWP 1546
DL K++E K++ ++K P DD +A L +++ +M D+WP
Sbjct: 2032 DLKKRKMEENTSINLSKQESFTSVKK---PKRDDSKDLA----LCSMILTEMETHEDAWP 2084
Query: 1547 FHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPES 1606
F PVN K VP Y K+I P+D TIR+ +S +Y + E+F DV L+ N +N +S
Sbjct: 2085 FLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDS 2144
Score = 56.2 bits (134), Expect = 3e-07
Identities = 28/94 (29%), Positives = 47/94 (50%)
Query: 1406 SILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFR 1465
++ I+ +M + PF PVN K+V Y K+I +PMD T+RE + YP+ E F
Sbjct: 2067 ALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETFA 2126
Query: 1466 EHLELIVKNSATYNGPKHSLTQISQSMLDLCDEK 1499
+ L+ N T+N + + +M ++K
Sbjct: 2127 LDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160
Score = 32.3 bits (72), Expect = 4.3
Identities = 20/56 (35%), Positives = 28/56 (50%)
Query: 1744 LADEEEGTVQQPEASVLYEDLLISEGEDDEEDAGSDEEGDNPFSAIQLSESGSDSD 1799
L ++ GT +S ED E EDDEE+ D+E D + S+S S+SD
Sbjct: 587 LVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESD 642
>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 62.8 bits (151), Expect = 3e-09
Identities = 42/153 (27%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Query: 1530 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESF 1587
L +V + + SWPF PV+ K +PDYY +I NP+DL TI+K + Y
Sbjct: 35 LQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASEC 94
Query: 1588 LDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITE--YDEHLTQLEKDI--CTAKEA 1643
++D N + +N YN P AQ + + Q +++ +E + +++ I T +
Sbjct: 95 IEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNI 154
Query: 1644 ALEEAELESLDPMTPGPYTSQPPDMYDTNTSLS 1676
A+ A+ +S T + Q TS+S
Sbjct: 155 AVSSAKEKSSPSATEKVFKQQEIPSVFPKTSIS 187
Score = 56.2 bits (134), Expect = 3e-07
Identities = 29/94 (30%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
Query: 1527 SFILDNIVTQKMMAVPDSWPFHHPV--NKKFVPDYYKMIVNPVDLETIRKNISKHKYQSR 1584
S IL ++ +K + +WPF++PV N + +YY ++ NP+DL TI++ + +Y+
Sbjct: 277 SEILKEMLAKKHFSY--AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDA 334
Query: 1585 ESFLDDVNLILANSVKYNGPESQYTKTAQEIVNI 1618
F DV L+ N KYN P+ + A+ + ++
Sbjct: 335 YKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
Score = 48.5 bits (114), Expect = 6e-05
Identities = 30/115 (26%), Positives = 58/115 (50%), Gaps = 4/115 (3%)
Query: 1404 LSSILESIINDMRDLPNTHPFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKCLYPSR 1461
L + + ++ D+ + PF PV+A ++ DYY II PMDL T+++ + Y
Sbjct: 32 LQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKA 91
Query: 1462 EEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE--KEDKLARLEKAI 1514
E E + N YN P + ++Q++ L +KL + +E+++ +++ I
Sbjct: 92 SECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERI 146
Score = 47.4 bits (111), Expect = 1e-04
Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 1423 PFHTPV--NAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNG 1480
PF+ PV NA + +YY ++ PMDL T++E + Y +F + L+ N YN
Sbjct: 294 PFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNP 353
Query: 1481 PKHSLTQISQSMLDL 1495
P H + +++ + D+
Sbjct: 354 PDHEVVTMARMLQDV 368
>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 62.8 bits (151), Expect = 3e-09
Identities = 42/153 (27%), Positives = 71/153 (46%), Gaps = 6/153 (3%)
Query: 1530 LDNIVTQKMMAVPDSWPFHHPVN--KKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESF 1587
L +V + + SWPF PV+ K +PDYY +I NP+DL TI+K + Y
Sbjct: 35 LQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKASEC 94
Query: 1588 LDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITE--YDEHLTQLEKDI--CTAKEA 1643
++D N + +N YN P AQ + + Q +++ +E + +++ I T +
Sbjct: 95 IEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERIKKGTQQNI 154
Query: 1644 ALEEAELESLDPMTPGPYTSQPPDMYDTNTSLS 1676
A+ A+ +S T + Q TS+S
Sbjct: 155 AVSSAKEKSSPSATEKVFKQQEIPSVFPKTSIS 187
Score = 56.2 bits (134), Expect = 3e-07
Identities = 29/94 (30%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
Query: 1527 SFILDNIVTQKMMAVPDSWPFHHPV--NKKFVPDYYKMIVNPVDLETIRKNISKHKYQSR 1584
S IL ++ +K + +WPF++PV N + +YY ++ NP+DL TI++ + +Y+
Sbjct: 277 SEILKEMLAKKHFSY--AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDA 334
Query: 1585 ESFLDDVNLILANSVKYNGPESQYTKTAQEIVNI 1618
F DV L+ N KYN P+ + A+ + ++
Sbjct: 335 YKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDV 368
Score = 48.5 bits (114), Expect = 6e-05
Identities = 30/115 (26%), Positives = 58/115 (50%), Gaps = 4/115 (3%)
Query: 1404 LSSILESIINDMRDLPNTHPFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKCLYPSR 1461
L + + ++ D+ + PF PV+A ++ DYY II PMDL T+++ + Y
Sbjct: 32 LQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYAKA 91
Query: 1462 EEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE--KEDKLARLEKAI 1514
E E + N YN P + ++Q++ L +KL + +E+++ +++ I
Sbjct: 92 SECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQMPQEEQVVGVKERI 146
Score = 47.4 bits (111), Expect = 1e-04
Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 1423 PFHTPV--NAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNG 1480
PF+ PV NA + +YY ++ PMDL T++E + Y +F + L+ N YN
Sbjct: 294 PFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNP 353
Query: 1481 PKHSLTQISQSMLDL 1495
P H + +++ + D+
Sbjct: 354 PDHEVVTMARMLQDV 368
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 62.4 bits (150), Expect = 4e-09
Identities = 39/138 (28%), Positives = 61/138 (44%), Gaps = 15/138 (10%)
Query: 1544 SWPFHHPVN--KKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKY 1601
+WPF PV+ K +PDYYK+I P+D+ TI+K + + Y + + + D N + N Y
Sbjct: 80 AWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIY 139
Query: 1602 NGPESQYTKTAQEIVNICYQTITEYDEHLTQL-----------EKDICTAKE--AALEEA 1648
N P A+ + + Q I E T++ K+ TAK + +
Sbjct: 140 NKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNT 199
Query: 1649 ELESLDPMTPGPYTSQPP 1666
S P T P + PP
Sbjct: 200 TQASTPPQTQTPQPNPPP 217
Score = 55.8 bits (133), Expect = 4e-07
Identities = 40/164 (24%), Positives = 73/164 (44%), Gaps = 20/164 (12%)
Query: 1527 SFILDNIVTQKMMAVPDSWPFHHPVNKKFVP--DYYKMIVNPVDLETIRKNISKHKYQSR 1584
S IL + +K A +WPF+ PV+ + + DY +I +P+D+ TI+ + +Y+
Sbjct: 358 SGILKEMFAKKHAAY--AWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDA 415
Query: 1585 ESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITEYDEHLTQLEKDICTAKEAA 1644
+ F DV L+ +N KYN P+ + A+++ ++ + +
Sbjct: 416 QEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE--------------- 460
Query: 1645 LEEAELESLDPMTPGP-YTSQPPDMYDTNTSLSTSRDASVFQDE 1687
EE + P P P PP D+++ S+ D+S E
Sbjct: 461 PEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSE 504
Score = 48.5 bits (114), Expect = 6e-05
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 1423 PFHTPVNAKVV--KDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNG 1480
PF+ PV+ + + DY II PMD+ T++ + Y +EF + L+ N YN
Sbjct: 375 PFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNP 434
Query: 1481 PKHSLTQISQSMLDLCDEKLKEKEDK 1506
P H + +++ + D+ + + + D+
Sbjct: 435 PDHEVVAMARKLQDVFEMRFAKMPDE 460
Score = 44.7 bits (104), Expect = 8e-04
Identities = 24/82 (29%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Query: 1423 PFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNG 1480
PF PV+A + DYYKII PMD+ T+++ + Y + +E + + N YN
Sbjct: 82 PFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK 141
Query: 1481 PKHSLTQISQSMLDLCDEKLKE 1502
P + +++++ L +K+ E
Sbjct: 142 PGDDIVLMAEALEKLFLQKINE 163
Score = 32.0 bits (71), Expect = 5.7
Identities = 31/131 (23%), Positives = 59/131 (45%), Gaps = 25/131 (19%)
Query: 1233 EKHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHM 1292
EK ++E +KE+ + +E++ K+++ KE PP KK KK +
Sbjct: 540 EKDKKEKKKEKHKRKEEVEENKKSKAKE----PPPKKTKKNNS--------------SNS 581
Query: 1293 RTNKFCPLYYQTNVPPSKPVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVFGKQLIENV 1352
+K P ++ PP T E EEE + + + + + ++ K+ G++L V
Sbjct: 582 NVSKKEPAPMKSKPPP------TYESEEEDKCKPMSYEEKRQLSLDINKLP-GEKLGRVV 634
Query: 1353 HEVRRKSLVLK 1363
H ++ + LK
Sbjct: 635 HIIQSREPSLK 645
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 62.4 bits (150), Expect = 4e-09
Identities = 39/138 (28%), Positives = 61/138 (44%), Gaps = 15/138 (10%)
Query: 1544 SWPFHHPVN--KKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKY 1601
+WPF PV+ K +PDYYK+I P+D+ TI+K + + Y + + + D N + N Y
Sbjct: 80 AWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIY 139
Query: 1602 NGPESQYTKTAQEIVNICYQTITEYDEHLTQL-----------EKDICTAKE--AALEEA 1648
N P A+ + + Q I E T++ K+ TAK + +
Sbjct: 140 NKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNT 199
Query: 1649 ELESLDPMTPGPYTSQPP 1666
S P T P + PP
Sbjct: 200 TQASTPPQTQTPQPNPPP 217
Score = 55.8 bits (133), Expect = 4e-07
Identities = 40/164 (24%), Positives = 73/164 (44%), Gaps = 20/164 (12%)
Query: 1527 SFILDNIVTQKMMAVPDSWPFHHPVNKKFVP--DYYKMIVNPVDLETIRKNISKHKYQSR 1584
S IL + +K A +WPF+ PV+ + + DY +I +P+D+ TI+ + +Y+
Sbjct: 358 SGILKEMFAKKHAAY--AWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDA 415
Query: 1585 ESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITEYDEHLTQLEKDICTAKEAA 1644
+ F DV L+ +N KYN P+ + A+++ ++ + +
Sbjct: 416 QEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE--------------- 460
Query: 1645 LEEAELESLDPMTPGP-YTSQPPDMYDTNTSLSTSRDASVFQDE 1687
EE + P P P PP D+++ S+ D+S E
Sbjct: 461 PEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSE 504
Score = 48.5 bits (114), Expect = 6e-05
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 1423 PFHTPVNAKVV--KDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNG 1480
PF+ PV+ + + DY II PMD+ T++ + Y +EF + L+ N YN
Sbjct: 375 PFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNP 434
Query: 1481 PKHSLTQISQSMLDLCDEKLKEKEDK 1506
P H + +++ + D+ + + + D+
Sbjct: 435 PDHEVVAMARKLQDVFEMRFAKMPDE 460
Score = 44.7 bits (104), Expect = 8e-04
Identities = 24/82 (29%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Query: 1423 PFHTPVNAKVVK--DYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNG 1480
PF PV+A + DYYKII PMD+ T+++ + Y + +E + + N YN
Sbjct: 82 PFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK 141
Query: 1481 PKHSLTQISQSMLDLCDEKLKE 1502
P + +++++ L +K+ E
Sbjct: 142 PGDDIVLMAEALEKLFLQKINE 163
Score = 32.0 bits (71), Expect = 5.7
Identities = 31/131 (23%), Positives = 59/131 (45%), Gaps = 25/131 (19%)
Query: 1233 EKHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHM 1292
EK ++E +KE+ + +E++ K+++ KE PP KK KK +
Sbjct: 540 EKDKKEKKKEKHKRKEEVEENKKSKAKE----PPPKKTKKNNS--------------SNS 581
Query: 1293 RTNKFCPLYYQTNVPPSKPVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVFGKQLIENV 1352
+K P ++ PP T E EEE + + + + + ++ K+ G++L V
Sbjct: 582 NVSKKEPAPMKSKPPP------TYESEEEDKCKPMSYEEKRQLSLDINKLP-GEKLGRVV 634
Query: 1353 HEVRRKSLVLK 1363
H ++ + LK
Sbjct: 635 HIIQSREPSLK 645
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
[Homo sapiens]
Length = 1524
Score = 62.0 bits (149), Expect = 5e-09
Identities = 32/102 (31%), Positives = 51/102 (50%)
Query: 1543 DSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYN 1602
DSWPF V+K VPDYY +I P+ L IR+ ++K +Y+ F+DD+ L+ +N +YN
Sbjct: 1418 DSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1477
Query: 1603 GPESQYTKTAQEIVNICYQTITEYDEHLTQLEKDICTAKEAA 1644
+ K + + + H+T D + AA
Sbjct: 1478 PRNTSEAKAGTRLQAFFHIQAQKLGLHVTPSNVDQVSTPPAA 1519
Score = 48.9 bits (115), Expect = 4e-05
Identities = 26/74 (35%), Positives = 39/74 (52%)
Query: 1406 SILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFR 1465
S E ++ ++ ++ PF V+ V DYY II +P+ L +RE V KC Y EF
Sbjct: 1404 SAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFI 1463
Query: 1466 EHLELIVKNSATYN 1479
+ +EL+ N YN
Sbjct: 1464 DDIELMFSNCFEYN 1477
Score = 36.2 bits (82), Expect = 0.30
Identities = 17/44 (38%), Positives = 33/44 (75%), Gaps = 1/44 (2%)
Query: 1232 DEKHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKE 1275
+++ +E+ R+E ++I E+ RLK+ +EKE+LK EK+ +K++E
Sbjct: 341 EKEDKEKKREELKKIVEE-ERLKKKEEKERLKVEREKEREKLRE 383
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/63 (31%), Positives = 37/63 (58%), Gaps = 5/63 (7%)
Query: 1220 KDEKFIQKFALFDEKHREEMRKERRRIQEQLR---RLKRNQEKEKLKGPPEKKPKKMKER 1276
K+EK ++ + EK RE++R+E+R+ E L+ + + + E + LK PE P K +
Sbjct: 364 KEEK--ERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDDLKELPEPTPVKTRLP 421
Query: 1277 PDL 1279
P++
Sbjct: 422 PEI 424
Score = 33.1 bits (74), Expect = 2.5
Identities = 37/125 (29%), Positives = 55/125 (44%), Gaps = 27/125 (21%)
Query: 1171 SMTSLKSSATGHCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRTTKDEKFIQKFAL 1230
++ S +S AT K+ + EE K + K DA + K++K
Sbjct: 296 TLASYRSKATKERDKL---LKQEEMKSLAFEKAKLKREKADALEAKKKEKEDK------- 345
Query: 1231 FDEKHREEMRK----ERRRIQEQLRRLKRNQEKEKLKGPPEK-----------KPKKMKE 1275
EK REE++K ER + +E+ RLK +EKE+ K EK KP++ E
Sbjct: 346 --EKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDME 403
Query: 1276 RPDLK 1280
DLK
Sbjct: 404 CDDLK 408
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
[Homo sapiens]
Length = 1556
Score = 62.0 bits (149), Expect = 5e-09
Identities = 32/102 (31%), Positives = 51/102 (50%)
Query: 1543 DSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYN 1602
DSWPF V+K VPDYY +I P+ L IR+ ++K +Y+ F+DD+ L+ +N +YN
Sbjct: 1450 DSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYN 1509
Query: 1603 GPESQYTKTAQEIVNICYQTITEYDEHLTQLEKDICTAKEAA 1644
+ K + + + H+T D + AA
Sbjct: 1510 PRNTSEAKAGTRLQAFFHIQAQKLGLHVTPSNVDQVSTPPAA 1551
Score = 48.9 bits (115), Expect = 4e-05
Identities = 26/74 (35%), Positives = 39/74 (52%)
Query: 1406 SILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFR 1465
S E ++ ++ ++ PF V+ V DYY II +P+ L +RE V KC Y EF
Sbjct: 1436 SAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFI 1495
Query: 1466 EHLELIVKNSATYN 1479
+ +EL+ N YN
Sbjct: 1496 DDIELMFSNCFEYN 1509
Score = 36.2 bits (82), Expect = 0.30
Identities = 17/44 (38%), Positives = 33/44 (75%), Gaps = 1/44 (2%)
Query: 1232 DEKHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKE 1275
+++ +E+ R+E ++I E+ RLK+ +EKE+LK EK+ +K++E
Sbjct: 341 EKEDKEKKREELKKIVEE-ERLKKKEEKERLKVEREKEREKLRE 383
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/63 (31%), Positives = 37/63 (58%), Gaps = 5/63 (7%)
Query: 1220 KDEKFIQKFALFDEKHREEMRKERRRIQEQLR---RLKRNQEKEKLKGPPEKKPKKMKER 1276
K+EK ++ + EK RE++R+E+R+ E L+ + + + E + LK PE P K +
Sbjct: 364 KEEK--ERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDDLKELPEPTPVKTRLP 421
Query: 1277 PDL 1279
P++
Sbjct: 422 PEI 424
Score = 33.1 bits (74), Expect = 2.5
Identities = 37/125 (29%), Positives = 55/125 (44%), Gaps = 27/125 (21%)
Query: 1171 SMTSLKSSATGHCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRTTKDEKFIQKFAL 1230
++ S +S AT K+ + EE K + K DA + K++K
Sbjct: 296 TLASYRSKATKERDKL---LKQEEMKSLAFEKAKLKREKADALEAKKKEKEDK------- 345
Query: 1231 FDEKHREEMRK----ERRRIQEQLRRLKRNQEKEKLKGPPEK-----------KPKKMKE 1275
EK REE++K ER + +E+ RLK +EKE+ K EK KP++ E
Sbjct: 346 --EKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDME 403
Query: 1276 RPDLK 1280
DLK
Sbjct: 404 CDDLK 408
>gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapiens]
Length = 1205
Score = 61.2 bits (147), Expect = 9e-09
Identities = 34/114 (29%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Query: 1499 KLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPD 1558
+L K +KL R + + + + + F+ +L + P + F PVN VPD
Sbjct: 567 ELIRKREKLKREQVKVQQAAMELELMPFNVLLRTTLDLLQEKDP-AHIFAEPVNLSEVPD 625
Query: 1559 YYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTA 1612
Y + I P+D T+R+ + H Y++ E F +D NLI+ N +KYN ++ + + A
Sbjct: 626 YLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNAKDTIFHRAA 679
Score = 56.2 bits (134), Expect = 3e-07
Identities = 27/79 (34%), Positives = 43/79 (54%)
Query: 1401 MVTLSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPS 1460
++ + +L + ++ +++ H F PVN V DY + I++PMD T+R + LY +
Sbjct: 591 LMPFNVLLRTTLDLLQEKDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRT 650
Query: 1461 REEFREHLELIVKNSATYN 1479
EEF E LIV N YN
Sbjct: 651 LEEFEEDFNLIVTNCMKYN 669
>gi|11321642 bromodomain containing protein 1 [Homo sapiens]
Length = 1058
Score = 60.1 bits (144), Expect = 2e-08
Identities = 77/321 (23%), Positives = 128/321 (39%), Gaps = 41/321 (12%)
Query: 1498 EKLKEKEDKLAR--LEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKF 1555
EKLK ++ K+ + +E + PL V +LD + + + F PV+ K
Sbjct: 546 EKLKREQVKVEQVAMELRLTPLT-----VLLRSVLDQLQDKDPARI-----FAQPVSLKE 595
Query: 1556 VPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEI 1615
VPDY I +P+D T+RK + Y++ F +D +LI+ N +KYN ++ + + A +
Sbjct: 596 VPDYLDHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRL 655
Query: 1616 VNICYQTITEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTSQPPDMYDTNTSL 1675
D+ L + LEEA L P P +P D + L
Sbjct: 656 ----------RDQGGVVLRQARREVDSIGLEEASGMHL-PERPAAAPRRPFSWEDVDRLL 704
Query: 1676 STSRDASVFQDE---SNLSVLDISTATPEKQMCQGQGRLGEEDSDVDVEGYDDEEEDGKP 1732
+ A + +E L +LD++ A + +L +++ + + P
Sbjct: 705 DPANRAHLGLEEQLRELLDMLDLTCAMKSSGSRSKRAKLLKKEIALLRNKLSQQHSQPLP 764
Query: 1733 KPPAPEGGDGDLADEEEGTVQQPEA--SVL--YEDLLISEGEDDEEDAGSDEEGDNPFSA 1788
P EG EE+G PEA VL E LL S+ E ++P
Sbjct: 765 TGPGLEG------FEEDGAALGPEAGEEVLPRLETLLQPRKRSRSTCGDSEVEEESPGKR 818
Query: 1789 IQLSESGSDSDVGYGGIRPKQ 1809
+ + G+GG R +Q
Sbjct: 819 LDAGLTN-----GFGGARSEQ 834
Score = 54.3 bits (129), Expect = 1e-06
Identities = 38/169 (22%), Positives = 80/169 (47%), Gaps = 17/169 (10%)
Query: 1311 PVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVFGKQLIENVHEVRRKSLVLKFPKQQLP 1370
P+ + + +++ +N+E +K K+ + ++L H++ R L+++ +++
Sbjct: 491 PLLRRLQSSLQSQRSSQQRENDEEMKAAKEKLKYWQRLR---HDLERARLLIELLRKREK 547
Query: 1371 PKKKRRVGTTVHCDYLNIPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTHPFHTPVNA 1430
K+++ + + ++ R T L+ +L S+++ ++D F PV+
Sbjct: 548 LKREQ----------VKVEQVAMELRLTP----LTVLLRSVLDQLQDKDPARIFAQPVSL 593
Query: 1431 KVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYN 1479
K V DY I PMD T+R+ + Y + EF E +LI+ N YN
Sbjct: 594 KEVPDYLDHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDLIIDNCMKYN 642
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 58.2 bits (139), Expect = 7e-08
Identities = 28/84 (33%), Positives = 48/84 (57%), Gaps = 2/84 (2%)
Query: 1542 PDSWPFHHPVNKKF--VPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSV 1599
P+S PF PV+ + +PDY+ ++ NP+DL TI++ + +YQ ++DDV L+ N+
Sbjct: 1068 PESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAW 1127
Query: 1600 KYNGPESQYTKTAQEIVNICYQTI 1623
YN S+ K ++ + Q I
Sbjct: 1128 LYNRKTSRVYKFCSKLAEVFEQEI 1151
Score = 40.0 bits (92), Expect = 0.021
Identities = 41/204 (20%), Positives = 86/204 (42%), Gaps = 15/204 (7%)
Query: 1308 PSKPVA--MTEEQEEELEKTVIHNDNEELIKVEGTKIVFGKQLIENVHEVRRKSLVL--- 1362
P PV TE Q E+ E + E ++ + Q+ E +KS +
Sbjct: 952 PDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVD 1011
Query: 1363 -KFPKQQLPPKKKRRV---GTTVHCDYLNIPHKSIHRRRTDPMVTLSSILESIINDMRDL 1418
K P+ ++ K++ GT + P K I + P +++ ++ R
Sbjct: 1012 EKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFK----PEELRQALMPTLEALYRQD 1067
Query: 1419 PNTHPFHTPVNAKV--VKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSA 1476
P + PF PV+ ++ + DY+ I+ PMDL T++ + Y ++ + + L+ N+
Sbjct: 1068 PESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAW 1127
Query: 1477 TYNGPKHSLTQISQSMLDLCDEKL 1500
YN + + + ++ ++++
Sbjct: 1128 LYNRKTSRVYKFCSKLAEVFEQEI 1151
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 58.2 bits (139), Expect = 7e-08
Identities = 28/84 (33%), Positives = 48/84 (57%), Gaps = 2/84 (2%)
Query: 1542 PDSWPFHHPVNKKF--VPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSV 1599
P+S PF PV+ + +PDY+ ++ NP+DL TI++ + +YQ ++DDV L+ N+
Sbjct: 1106 PESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAW 1165
Query: 1600 KYNGPESQYTKTAQEIVNICYQTI 1623
YN S+ K ++ + Q I
Sbjct: 1166 LYNRKTSRVYKFCSKLAEVFEQEI 1189
Score = 40.0 bits (92), Expect = 0.021
Identities = 41/204 (20%), Positives = 86/204 (42%), Gaps = 15/204 (7%)
Query: 1308 PSKPVA--MTEEQEEELEKTVIHNDNEELIKVEGTKIVFGKQLIENVHEVRRKSLVL--- 1362
P PV TE Q E+ E + E ++ + Q+ E +KS +
Sbjct: 990 PDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVD 1049
Query: 1363 -KFPKQQLPPKKKRRV---GTTVHCDYLNIPHKSIHRRRTDPMVTLSSILESIINDMRDL 1418
K P+ ++ K++ GT + P K I + P +++ ++ R
Sbjct: 1050 EKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFK----PEELRQALMPTLEALYRQD 1105
Query: 1419 PNTHPFHTPVNAKV--VKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSA 1476
P + PF PV+ ++ + DY+ I+ PMDL T++ + Y ++ + + L+ N+
Sbjct: 1106 PESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAW 1165
Query: 1477 TYNGPKHSLTQISQSMLDLCDEKL 1500
YN + + + ++ ++++
Sbjct: 1166 LYNRKTSRVYKFCSKLAEVFEQEI 1189
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 57.8 bits (138), Expect = 1e-07
Identities = 36/136 (26%), Positives = 63/136 (46%), Gaps = 6/136 (4%)
Query: 1488 ISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPF 1547
I QS +L DE + + + PL + D + +L ++ KM +WPF
Sbjct: 2756 ILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYE-GLKRVLRSLQAHKM-----AWPF 2809
Query: 1548 HHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1607
PV+ PDYY +I P+DL T+ + + + Y+ F+ D+ I N YN +S
Sbjct: 2810 LEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSP 2869
Query: 1608 YTKTAQEIVNICYQTI 1623
+ + A+ + + Q +
Sbjct: 2870 FYQCAEVLESFFVQKL 2885
Score = 47.0 bits (110), Expect = 2e-04
Identities = 27/94 (28%), Positives = 42/94 (44%)
Query: 1408 LESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREH 1467
L+ ++ ++ PF PV+ DYY +I PMDL T+ E V++ Y EF
Sbjct: 2793 LKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVAD 2852
Query: 1468 LELIVKNSATYNGPKHSLTQISQSMLDLCDEKLK 1501
+ I N YN Q ++ + +KLK
Sbjct: 2853 MTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK 2886
Score = 31.2 bits (69), Expect = 9.7
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 10/64 (15%)
Query: 1713 EEDSDVDVEGYDDEEEDGKPKPPAPEGGDGDLADEEEGTVQQPEASVLYEDLLISEGEDD 1772
EE+ + D+ ++EEEDG A E D + D+EE +++ + Y + E EDD
Sbjct: 133 EEEEEEDMVSEEEEEEDG----DAEETQDSE--DDEEDEMEEDDDDSDYPE----EMEDD 182
Query: 1773 EEDA 1776
++DA
Sbjct: 183 DDDA 186
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 57.8 bits (138), Expect = 1e-07
Identities = 36/136 (26%), Positives = 63/136 (46%), Gaps = 6/136 (4%)
Query: 1488 ISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPF 1547
I QS +L DE + + + PL + D + +L ++ KM +WPF
Sbjct: 2773 ILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYE-GLKRVLRSLQAHKM-----AWPF 2826
Query: 1548 HHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQ 1607
PV+ PDYY +I P+DL T+ + + + Y+ F+ D+ I N YN +S
Sbjct: 2827 LEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSP 2886
Query: 1608 YTKTAQEIVNICYQTI 1623
+ + A+ + + Q +
Sbjct: 2887 FYQCAEVLESFFVQKL 2902
Score = 47.0 bits (110), Expect = 2e-04
Identities = 27/94 (28%), Positives = 42/94 (44%)
Query: 1408 LESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREH 1467
L+ ++ ++ PF PV+ DYY +I PMDL T+ E V++ Y EF
Sbjct: 2810 LKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVAD 2869
Query: 1468 LELIVKNSATYNGPKHSLTQISQSMLDLCDEKLK 1501
+ I N YN Q ++ + +KLK
Sbjct: 2870 MTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK 2903
Score = 31.2 bits (69), Expect = 9.7
Identities = 21/64 (32%), Positives = 35/64 (54%), Gaps = 10/64 (15%)
Query: 1713 EEDSDVDVEGYDDEEEDGKPKPPAPEGGDGDLADEEEGTVQQPEASVLYEDLLISEGEDD 1772
EE+ + D+ ++EEEDG A E D + D+EE +++ + Y + E EDD
Sbjct: 133 EEEEEEDMVSEEEEEEDG----DAEETQDSE--DDEEDEMEEDDDDSDYPE----EMEDD 182
Query: 1773 EEDA 1776
++DA
Sbjct: 183 DDDA 186
>gi|34996489 pleckstrin homology domain interacting protein [Homo
sapiens]
Length = 1821
Score = 57.8 bits (138), Expect = 1e-07
Identities = 52/263 (19%), Positives = 96/263 (36%), Gaps = 40/263 (15%)
Query: 1412 INDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELI 1471
IN + L F PV+ + Y ++ P DL T+++ + Y + I
Sbjct: 1172 INQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYI 1231
Query: 1472 VKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE--DKLARLEKAINPLLDDDDQVAFSFI 1529
N+ T+N P + + ++ + DL +K++ + + +L D +
Sbjct: 1232 EHNTRTFNEPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEDEEKDAD 1291
Query: 1530 LDNIVTQK--------------------------------MMAVPDSWPFHHPVNKKFVP 1557
+ T+K + DS PF PV+ P
Sbjct: 1292 VPGTSTRKRKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCEDSEPFRQPVDLLEYP 1351
Query: 1558 DYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVN 1617
DY +I P+D T+R+ + Y+S DV LI +NS Y I +
Sbjct: 1352 DYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYT------PSKRSRIYS 1405
Query: 1618 ICYQTITEYDEHLTQLEKDICTA 1640
+ + ++EH++ + D +A
Sbjct: 1406 MSLRLSAFFEEHISSVLSDYKSA 1428
Score = 45.8 bits (107), Expect = 4e-04
Identities = 34/140 (24%), Positives = 61/140 (43%), Gaps = 20/140 (14%)
Query: 1537 KMMAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILA 1596
++M + + F PV+ + P Y ++ P DL TI++ + Y+ S + +V I
Sbjct: 1174 QLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEH 1233
Query: 1597 NSVKYNGPESQYTKTAQEIVNI---------CYQTITEYDEHLTQLEKDICTAKEAALEE 1647
N+ +N P S K+A+ + ++ CY I Y+ + K+ L +
Sbjct: 1234 NTRTFNEPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYN-----------SMKKKVLSD 1282
Query: 1648 AELESLDPMTPGPYTSQPPD 1667
+E E D PG T + D
Sbjct: 1283 SEDEEKDADVPGTSTRKRKD 1302
Score = 45.8 bits (107), Expect = 4e-04
Identities = 26/76 (34%), Positives = 36/76 (47%)
Query: 1409 ESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHL 1468
E ++N + ++ PF PV+ DY II PMD T+RE + Y S E + +
Sbjct: 1326 EELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDV 1385
Query: 1469 ELIVKNSATYNGPKHS 1484
LI NS Y K S
Sbjct: 1386 RLIFSNSKAYTPSKRS 1401
Score = 31.2 bits (69), Expect = 9.7
Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Query: 1233 EKHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKERPDLKLKCG 1284
E +E + ++ Q+Q+++ K+ +EK GP K KK KER +L G
Sbjct: 878 ESSSDEEEESEKQKQKQIKKEKKKVNEEK-DGPISPKKKKPKERKQKRLAVG 928
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 57.4 bits (137), Expect = 1e-07
Identities = 48/185 (25%), Positives = 81/185 (43%), Gaps = 25/185 (13%)
Query: 1441 TRPMDLQTLRENVRKCLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKL 1500
T+P D+ V C S E EL + + P S TQ S + +
Sbjct: 992 TQPEDIS--ESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPA-----PGQS 1044
Query: 1501 KEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKF--VPD 1558
K+K K L +A+ P L+ + Q P+S PF PV+ + +PD
Sbjct: 1045 KKKIFKPEELRQALMPTLEA------------LYRQD----PESLPFRQPVDPQLLGIPD 1088
Query: 1559 YYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNI 1618
Y+ ++ +P+DL TI++ + +YQ ++DD+ L+ N+ YN S+ K ++ +
Sbjct: 1089 YFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEV 1148
Query: 1619 CYQTI 1623
Q I
Sbjct: 1149 FEQEI 1153
Score = 38.1 bits (87), Expect = 0.079
Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
Query: 1416 RDLPNTHPFHTPVNAKV--VKDYYKIITRPMDLQTLRENVRKCLYPSREEFREHLELIVK 1473
R P + PF PV+ ++ + DY+ I+ PMDL T++ + Y ++ + + L+
Sbjct: 1067 RQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFN 1126
Query: 1474 NSATYN 1479
N+ YN
Sbjct: 1127 NAWLYN 1132
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,349,180
Number of Sequences: 37866
Number of extensions: 4098132
Number of successful extensions: 24419
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 335
Number of HSP's that attempted gapping in prelim test: 20614
Number of HSP's gapped (non-prelim): 3437
length of query: 1826
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1709
effective length of database: 13,817,196
effective search space: 23613587964
effective search space used: 23613587964
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.