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Search of human proteins with 24308289
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308289 leukocyte receptor cluster (LRC) member 1 [Homo
sapiens]
(264 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308289 leukocyte receptor cluster (LRC) member 1 [Homo sapi... 532 e-151
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 51 9e-07
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 49 4e-06
gi|148746195 trichohyalin [Homo sapiens] 49 4e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 49 6e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 49 6e-06
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 48 8e-06
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 47 1e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 1e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 47 1e-05
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 47 2e-05
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 46 3e-05
gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 46 3e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 46 4e-05
gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapi... 46 4e-05
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 45 5e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 6e-05
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 45 6e-05
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 45 8e-05
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 45 8e-05
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 44 1e-04
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 44 1e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 44 1e-04
gi|16262452 cingulin [Homo sapiens] 44 1e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 44 1e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 44 1e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 44 1e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 44 1e-04
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 44 1e-04
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 44 1e-04
>gi|24308289 leukocyte receptor cluster (LRC) member 1 [Homo
sapiens]
Length = 264
Score = 532 bits (1371), Expect = e-151
Identities = 264/264 (100%), Positives = 264/264 (100%)
Query: 1 MNILPKKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSL 60
MNILPKKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSL
Sbjct: 1 MNILPKKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSL 60
Query: 61 PELEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQS 120
PELEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQS
Sbjct: 61 PELEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQS 120
Query: 121 AAEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRK 180
AAEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRK
Sbjct: 121 AAEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRK 180
Query: 181 EKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
EKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRR
Sbjct: 181 EKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
Query: 241 RRYNSQFNPQLARRPRQQDPHLTH 264
RRYNSQFNPQLARRPRQQDPHLTH
Sbjct: 241 RRYNSQFNPQLARRPRQQDPHLTH 264
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 51.2 bits (121), Expect = 9e-07
Identities = 65/262 (24%), Positives = 105/262 (40%), Gaps = 34/262 (12%)
Query: 11 VRNKDNVARVRRDEAQAREEEKERERRV--LLAQQEARTEFLRKKARHQNSLPELEAAEA 68
V ++ + R + A+ +E+E+E ERR Q +AR E+ R+K R E E
Sbjct: 97 VHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREM--AREHSRRER 154
Query: 69 GAPGSGPVDLFRELLE-------------EGKGVIRGNKEYE---EEKRQEKERQEKALG 112
G G V LFR+ LE E + R KE E EE+R+E+E + +
Sbjct: 155 GNDG---VCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSA 211
Query: 113 ILTYLGQSAAEAQTQPPWYQLPPG------RGGPPPGPAPDEKIKSRLDPLREMQKHLGK 166
+ + ++ W + PP G P +EK++ R D L ++Q
Sbjct: 212 HHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER-DLLSDLQDISDS 270
Query: 167 KRQHGGDEGSR----SRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQ 222
+R+ E S S E+E E++ +E S + E E E +
Sbjct: 271 ERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEAS 330
Query: 223 GRALQEGQPEEDETDDRRRRYN 244
++ +E EE D+ R N
Sbjct: 331 EQSAEEVSEEEMSEDEERENEN 352
Score = 41.2 bits (95), Expect = 0.001
Identities = 36/122 (29%), Positives = 53/122 (43%), Gaps = 8/122 (6%)
Query: 140 PPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQL 199
PP + EK+ R D R+ +KH K + E R R +E + +R E ++
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHE-RRKRHREEQDKARREWERQKRREM 145
Query: 200 RAERLRREAAE------RSRAEAL-LARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLA 252
E RRE R R E L R + R ++E Q E+ E +R RR + + A
Sbjct: 146 AREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREA 205
Query: 253 RR 254
RR
Sbjct: 206 RR 207
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 48.9 bits (115), Expect = 4e-06
Identities = 62/255 (24%), Positives = 102/255 (40%), Gaps = 22/255 (8%)
Query: 6 KKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKAR---HQNSLPE 62
K+ H R KD + + A+ +E E ER +R Q +AR E+ R+K R ++S E
Sbjct: 94 KEKVHHR-KDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 152
Query: 63 LEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYE---EEKRQEKERQEKALGILTYLGQ 119
+ E RE +E R KE E EE+R+E+E + + + +
Sbjct: 153 RDRLEQLERKRERERKMREQQKEQ----REQKERERRAEERRKEREARREVSAHHRTMRE 208
Query: 120 SAAEAQTQPPWYQLPPG------RGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGD 173
++ W + PP G P +EK++ R D L ++Q +R+
Sbjct: 209 DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER-DLLSDLQDISDSERKTSSA 267
Query: 174 EGSR----SRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEG 229
E S S E+E E++ +E S + E E E + ++ +E
Sbjct: 268 ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEV 327
Query: 230 QPEEDETDDRRRRYN 244
EE D+ R N
Sbjct: 328 SEEEMSEDEERENEN 342
Score = 40.4 bits (93), Expect = 0.002
Identities = 37/118 (31%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 140 PPPGPAPDEKIKSRLDPLR-EMQKHLG-KKRQHGGDEGSRSRKEKEGSEKQRPK-EPPSL 196
PP + EK+ R D R E KH K+R+H + R ++K E +R K +
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAR 146
Query: 197 DQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARR 254
+ R ER R E ER R + R ++E Q E+ E +R RR + + ARR
Sbjct: 147 EHSRRERDRLEQLERKRE-------RERKMREQQKEQREQKERERRAEERRKEREARR 197
Score = 30.4 bits (67), Expect = 1.7
Identities = 22/102 (21%), Positives = 44/102 (43%), Gaps = 2/102 (1%)
Query: 157 LREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEA 216
++ Q+ K++ H + R K K K+R E + ++ RRE + R E
Sbjct: 85 IKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRRE- 143
Query: 217 LLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPRQQ 258
+AR R ++ + + +R R+ Q Q ++ R++
Sbjct: 144 -MAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERER 184
Score = 28.9 bits (63), Expect = 4.8
Identities = 18/79 (22%), Positives = 33/79 (41%)
Query: 181 EKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
E G E P R E++ E+ + + ARV+ R + + +E D R
Sbjct: 74 EDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKAR 133
Query: 241 RRYNSQFNPQLARRPRQQD 259
R + Q ++AR +++
Sbjct: 134 REWERQKRREMAREHSRRE 152
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 48.9 bits (115), Expect = 4e-06
Identities = 57/263 (21%), Positives = 117/263 (44%), Gaps = 41/263 (15%)
Query: 6 KKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEA 65
++ +R + + R + +E ++ E+ER + L +QE R ++L+++ + E
Sbjct: 414 RREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK 473
Query: 66 AEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQ 125
+ L R+ EE + R K EEE+R+++ER+E+ L + E +
Sbjct: 474 QQ----------LKRDQEEERRE--RWLKLEEEERREQQERREQQLR------REQEERR 515
Query: 126 TQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGS 185
Q Q +E+++ RL +++++ ++R+ R E+E
Sbjct: 516 EQRLKRQ------------EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563
Query: 186 EKQRPKEPPSL-DQL--RAERLRREAAERSRAEALLARVQGRALQEGQPEE--------D 234
E++ +E DQL R E R++ +R + E L R++ ++ + EE +
Sbjct: 564 EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKRE 623
Query: 235 ETDDRRRRYNSQFNPQLARRPRQ 257
E ++ RR+ + Q RR +Q
Sbjct: 624 EPEEERRQQLLKSEEQEERRQQQ 646
Score = 47.0 bits (110), Expect = 2e-05
Identities = 56/243 (23%), Positives = 97/243 (39%), Gaps = 30/243 (12%)
Query: 19 RVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDL 78
R RRDE R+ ++ +ER A++E + K P+ E
Sbjct: 166 RQRRDEELWRQRQEWQEREERRAEEE---QLQSCKGHETEEFPDEEQLRR---------- 212
Query: 79 FRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRG 138
RELLE + K EE+++Q +ERQ++ E + +L
Sbjct: 213 -RELLELRR------KGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE- 264
Query: 139 GPPPGPAPDEKIKSRLDPLREMQKH-LGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLD 197
P +++ + LR++++ L ++RQ + R R+E++ KQ + +
Sbjct: 265 -----PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Query: 198 QLRAERLRREAAERSRAEALLARVQGR---ALQEGQPEEDETDDRRRRYNSQFNPQLARR 254
+ R ++ RRE E R + L + R L+ Q EE RR + Q RR
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379
Query: 255 PRQ 257
+Q
Sbjct: 380 EQQ 382
Score = 46.2 bits (108), Expect = 3e-05
Identities = 60/246 (24%), Positives = 107/246 (43%), Gaps = 23/246 (9%)
Query: 19 RVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDL 78
+ R +E Q R +E RER+ L +Q+ R E RK + L E E + +
Sbjct: 1431 KFREEEQQVRRQE--RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQ-----ER 1483
Query: 79 FRELLEEGKGVIR--GNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPG 136
R+ LEE + + R ++++ E++ + +E + K L L + + + QL
Sbjct: 1484 DRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ 1543
Query: 137 RGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSL 196
G D K + + LR+ ++ RQ D R ++K ++Q K
Sbjct: 1544 ERGQQRRQDRDRKFREE-EQLRQEREEQQLSRQE-RDRKFRLEEQKVRRQEQERKFMEDE 1601
Query: 197 DQLR----AERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLA 252
QLR ++LR+E + R + L LQE + ++ +R R++ + PQL
Sbjct: 1602 QQLRRQEGQQQLRQERDRKFREDEQL-------LQEREEQQLHRQERDRKFLEE-EPQLR 1653
Query: 253 RRPRQQ 258
R+ R+Q
Sbjct: 1654 RQEREQ 1659
Score = 45.4 bits (106), Expect = 5e-05
Identities = 56/268 (20%), Positives = 111/268 (41%), Gaps = 51/268 (19%)
Query: 20 VRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLF 79
++ +E + RE+++ RE+++ Q+E R + L+++ + L + + L
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ---------QLR 539
Query: 80 RELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGG 139
RE E + +++ EEEKR E+ER+E+ L + + + + R
Sbjct: 540 REQEERREQLLKR----EEEKRLEQERREQRL--------KREQEERRDQLLKREEERRQ 587
Query: 140 PPPGPAPDEKIKSRL---------------------DPLREMQKHLGKKRQHGGDEGSRS 178
+E+++ RL +P E ++ L K + +
Sbjct: 588 QRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQL 647
Query: 179 RKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPE------ 232
R+E++ +QR K ++L +RL+RE E R + L Q +A + +
Sbjct: 648 RREQQERREQRLKREEEEERLE-QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQW 706
Query: 233 --EDETDDRRRRYNSQFNPQLARRPRQQ 258
E E D R+ + S+ Q +R RQ+
Sbjct: 707 QLESEADARQSKVYSRPRKQEGQRRRQE 734
Score = 45.4 bits (106), Expect = 5e-05
Identities = 53/249 (21%), Positives = 105/249 (42%), Gaps = 40/249 (16%)
Query: 11 VRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGA 70
+R ++ + R +E Q R +E RER+ L +Q+ R + L +K R + L + E
Sbjct: 1684 LRRQERDRKFREEEQQLRRQE--RERKFLQEEQQLRRQELERKFREEEQLRQ----ETEQ 1737
Query: 71 PGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPW 130
+ +R++LEE + +R +E ++ +RQE++R+ + L Q E Q +
Sbjct: 1738 EQLRRQERYRKILEEEQ--LRPEREEQQLRRQERDRKFREE---EQLRQEREEQQLR--- 1789
Query: 131 YQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRP 190
D K + +E ++ + +Q G K R
Sbjct: 1790 ------------SQESDRKFREEEQLRQEREEQQLRPQQRDG--------------KYRW 1823
Query: 191 KEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQ 250
+E + + +RLR+E + RAE A + +E + ++E RR+ + +
Sbjct: 1824 EEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREE 1883
Query: 251 LARRPRQQD 259
RR ++++
Sbjct: 1884 HIRRQQKEE 1892
Score = 43.5 bits (101), Expect = 2e-04
Identities = 54/241 (22%), Positives = 105/241 (43%), Gaps = 31/241 (12%)
Query: 24 EAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFRELL 83
E Q R EE+++ + L ++E + + R++ + L LE E + ++L
Sbjct: 795 ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR----ERAQQLQ 850
Query: 84 EEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPPPG 143
EE G+ ++ E + QE+ R +K + Q E + + R
Sbjct: 851 EEEDGL---QEDQERRRSQEQRRDQK------WRWQLEEERKRR---------RHTLYAK 892
Query: 144 PAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAER 203
PA E+++ L+E ++ L ++ + + R+ +E E+Q +E L + E+
Sbjct: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE--EEQLQQEEEQLLREEREK 950
Query: 204 LRREAAERS-RAEALLARVQGRALQEGQPEEDETDDRRRRYN-----SQFNPQLARRPRQ 257
RR+ ER R + L + + + L E +PE+ +R ++Y Q QL R R+
Sbjct: 951 RRRQERERQYRKDKKLQQKEEQLLGE-EPEKRRRQEREKKYREEEELQQEEEQLLREERE 1009
Query: 258 Q 258
+
Sbjct: 1010 K 1010
Score = 43.1 bits (100), Expect = 2e-04
Identities = 68/285 (23%), Positives = 109/285 (38%), Gaps = 58/285 (20%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFR 80
RRD+ REEE+ ++R L +QE R E R K L + E E P + R
Sbjct: 574 RRDQLLKREEERRQQR--LKREQEERLE-QRLKREEVERLEQEERREQRLKREEPEEERR 630
Query: 81 ELL-----EEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPP 135
+ L +E + + +E +E + Q +R+E+ + L + E + + +
Sbjct: 631 QQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQ 690
Query: 136 GRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHG------GDEGSRSRKEKEGSEKQR 189
+ E+IKSR+ + + RQ EG R R+E+E ++R
Sbjct: 691 EQAR--------ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742
Query: 190 PKEPPSLDQLRAERLRREAAER----------------------------SRAEALLARV 221
E ++ RA R ++E +R R L A
Sbjct: 743 ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEE 802
Query: 222 QGRALQEGQPEEDETDDRRRRYNS-----QF---NPQLARRPRQQ 258
+ + Q PEE+E + RRR+ QF QL RR R Q
Sbjct: 803 RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQ 847
Score = 42.0 bits (97), Expect = 5e-04
Identities = 59/251 (23%), Positives = 108/251 (43%), Gaps = 45/251 (17%)
Query: 14 KDNVARVRRDEAQAREEEKE-RERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPG 72
K R R+D EEEKE R+R +L ++E + + ++ + Q L E E
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ--EEEPQRQRELQEEEEQLRKLER 283
Query: 73 SGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQ 132
+L RE EE + R +E + ++QE+ER+E+ + E Q +
Sbjct: 284 Q---ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ--------EERREQQER----- 327
Query: 133 LPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKE 192
+ + + RE Q L ++++ ++ R +E+E E+Q +E
Sbjct: 328 ------------------REQQEERREQQ--LRREQEERREQQLRREQEEERREQQLRRE 367
Query: 193 PPSLDQLRAERLRREAAERSRAEALLARVQ--GRALQEGQPEEDETDDRRRRYNSQFNPQ 250
++ R ++LRRE ++ R E L R Q R Q + ++ + + RR Q
Sbjct: 368 QE--EERREQQLRRE--QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 423
Query: 251 LARRPRQQDPH 261
RR ++++ H
Sbjct: 424 QLRREQEEERH 434
Score = 41.2 bits (95), Expect = 0.001
Identities = 56/241 (23%), Positives = 105/241 (43%), Gaps = 38/241 (15%)
Query: 14 KDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGS 73
++ + ++ R E + +E+E++++ L +Q+ R + ++ Q E +
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334
Query: 74 GPVDLFRELLEEGKGVIRGNKEYEEEKR-------QEKERQEKALGILTYLGQSAAEAQT 126
L RE E + +R +E EEE+R QE+ER+E+ L L + +
Sbjct: 335 REQQLRREQEERREQQLR--REQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392
Query: 127 QPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSE 186
Q QL +++++ RE Q L +++Q ++ R +E+E E
Sbjct: 393 Q----QL-----------RREQQLRREQQLRREQQ--LRREQQLRREQQLRREQEEERHE 435
Query: 187 KQRPKEPPSLDQLRAERLRREAAER----SRAEALLARVQGRALQEGQPEEDETDDRRRR 242
++ +E R +RL+RE ER R E Q R Q Q + D+ ++RR R
Sbjct: 436 QKHEQER------REQRLKREQEERRDWLKREEETERHEQERRKQ--QLKRDQEEERRER 487
Query: 243 Y 243
+
Sbjct: 488 W 488
Score = 41.2 bits (95), Expect = 0.001
Identities = 60/262 (22%), Positives = 105/262 (40%), Gaps = 23/262 (8%)
Query: 11 VRNKDNVARVRRDEAQAREEEK--ERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEA 68
+R + R + E Q REEE+ + E ++L +QE R + ++ R + L + +
Sbjct: 1154 LREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213
Query: 69 GAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQ-----------EKALGILTYL 117
DL + E + +R NK Y + + E+ RQ ++ L L
Sbjct: 1214 YRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGE 1273
Query: 118 GQSAAEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSR 177
Q Q + W Q ++K R D + +K L + +E
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR------EEREE 1327
Query: 178 SRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERS-RAEALLARVQGRALQEGQPEEDET 236
R+ +E K R +E L + + LRR+ +R R E L + QGR E + +
Sbjct: 1328 KRRRQETDRKFR-EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLE-EEQRLRR 1385
Query: 237 DDRRRRYNSQFNPQLARRPRQQ 258
+R R++ + QL + R+Q
Sbjct: 1386 QERERKFLKE-EQQLRCQEREQ 1406
Score = 40.8 bits (94), Expect = 0.001
Identities = 52/239 (21%), Positives = 94/239 (39%), Gaps = 33/239 (13%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFR 80
RR++ RE+E+ER + L +Q+ R E ++ R + L + L R
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRRE---QQLRREQQLRREQQLRREQQLRREQQLRR 415
Query: 81 EL-LEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGG 139
E L + + R +E E++ E+ER+E+ L E + + W
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRL---------KREQEERRDW--------- 457
Query: 140 PPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQL 199
+K + R Q+ ++ + +E R R K E++R ++ QL
Sbjct: 458 ----------LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQL 507
Query: 200 RAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPRQQ 258
R E+ R R E R+Q R E Q ++ + R + + +L + R+Q
Sbjct: 508 RREQEERREQRLKRQEEE-ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ 565
Score = 38.5 bits (88), Expect = 0.006
Identities = 49/205 (23%), Positives = 90/205 (43%), Gaps = 12/205 (5%)
Query: 11 VRNKDNVARVRRDEAQAREEEKERE-RRVLLAQQEARTEFLRKKARHQNSLPELE-AAEA 68
+R ++ + ++E Q R +E ER+ R +QE E LR++ R++ L E + E
Sbjct: 1700 LRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPER 1759
Query: 69 GAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQP 128
+ R+ EE + +R +E ++ + QE +R+ + L Q E Q +P
Sbjct: 1760 EEQQLRRQERDRKFREEEQ--LRQEREEQQLRSQESDRKFRE---EEQLRQEREEQQLRP 1814
Query: 129 PWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQ 188
Q G+ E+ + RL R+ Q + Q E SR +++ E++
Sbjct: 1815 ---QQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR--AEEQFATQEKSRREEQELWQEEE 1869
Query: 189 RPKEPPSLDQLRAERLRREAAERSR 213
+ + +LR E +RR+ E R
Sbjct: 1870 QKRRQERERKLREEHIRRQQKEEQR 1894
Score = 37.0 bits (84), Expect = 0.018
Identities = 58/248 (23%), Positives = 96/248 (38%), Gaps = 69/248 (27%)
Query: 11 VRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGA 70
+R + R++ E Q REEE+ ++ L +E T ++ R EL+ E
Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE--- 1090
Query: 71 PGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPW 130
+LL E E E+ +RQE+ER Q E + Q
Sbjct: 1091 ---------EQLLRE---------EPEKRRRQERER------------QCREEEELQQEE 1120
Query: 131 YQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRP 190
QL LRE ++ K+R+ + R +E + E+Q
Sbjct: 1121 EQL-----------------------LREERE---KRRRQELERQYREEEEVQQEEEQLL 1154
Query: 191 KEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQ 250
+E P +R R+E + R E L + + + L+E Q E +R R+Y + +
Sbjct: 1155 REEPE------KRRRQELERQYREEEELQQEEEQLLREEQ--EKRRQERERQYREE--EE 1204
Query: 251 LARRPRQQ 258
L R+ R+Q
Sbjct: 1205 LQRQKRKQ 1212
Score = 35.4 bits (80), Expect = 0.051
Identities = 59/263 (22%), Positives = 103/263 (39%), Gaps = 32/263 (12%)
Query: 12 RNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAP 71
R + R + E Q REEE+ ++ L ++E +++ R +L+ E
Sbjct: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL 974
Query: 72 GSGPVDLFR-----------ELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQS 120
G P R EL +E + ++R +E E+ +RQE ERQ + L +
Sbjct: 975 GEEPEKRRRQEREKKYREEEELQQEEEQLLR--EEREKRRRQEWERQYRKKDELQQEEEQ 1032
Query: 121 AAEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRK 180
+ + Q + +E+ L RE ++ +RQ+ +E + +
Sbjct: 1033 LLREEREKRRLQERERQYREEEELQQEEE--QLLGEERETRRRQELERQYRKEEELQQEE 1090
Query: 181 E---KEGSEKQRP-------KEPPSLDQ-----LRAER--LRREAAERSRAEALLARVQG 223
E +E EK+R +E L Q LR ER RR+ ER E + +
Sbjct: 1091 EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE 1150
Query: 224 RALQEGQPEEDETDDRRRRYNSQ 246
L +PE+ + R+Y +
Sbjct: 1151 EQLLREEPEKRRRQELERQYREE 1173
Score = 31.2 bits (69), Expect = 0.97
Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 9/119 (7%)
Query: 148 EKIKSRLDPL-REMQKHLGKKRQHGGDEGSRSRKE-KEGSEKQRPKEPPSLDQLRAE--R 203
E+ + R +P R++++ G++R+ E R E +E SEKQ E + E R
Sbjct: 116 EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175
Query: 204 LRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRR-----RYNSQFNPQLARRPRQ 257
R+E ER A ++Q E + DE RRR R + Q RR RQ
Sbjct: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQ 234
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 48.5 bits (114), Expect = 6e-06
Identities = 47/227 (20%), Positives = 100/227 (44%), Gaps = 24/227 (10%)
Query: 11 VRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGA 70
+R ++ R++ + RE E+++ERR ++E R K+ + + E +
Sbjct: 38 IREREREIETRKEGKKERESERKKERR----EREKRKREREKERKRERGKKEKKGERKK- 92
Query: 71 PGSGPVDLFRELLEEGKGVIRGNKEYEE-EKRQEKERQEKALGILTYLGQSAAEAQTQPP 129
E + + + NKE EE EKR++KE++E+ G+++ E + +
Sbjct: 93 ---------EERERKKRRREKENKEGEEKEKRKKKEKKER--------GRTSKEGKERER 135
Query: 130 WYQLP-PGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQ 188
+ R EK + R + + +K +G+K + ++ + RK++E + K+
Sbjct: 136 KEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195
Query: 189 RPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDE 235
R KE ++ ++ R++ ER + + R + G+ E E
Sbjct: 196 RKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
Score = 40.0 bits (92), Expect = 0.002
Identities = 35/167 (20%), Positives = 73/167 (43%), Gaps = 6/167 (3%)
Query: 94 KEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSR 153
+E E+ KR+ ++ +++ G G+ E + + + + G EK K +
Sbjct: 64 REREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK-----EKRKKK 118
Query: 154 LDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAERLR-REAAERS 212
R GK+R+ + RKE+E +++R KE ++ + ER + E E
Sbjct: 119 EKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEER 178
Query: 213 RAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPRQQD 259
+ + R + ++ + +E E +RR R + + ++ RQ+D
Sbjct: 179 KEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKD 225
Score = 40.0 bits (92), Expect = 0.002
Identities = 45/203 (22%), Positives = 86/203 (42%), Gaps = 35/203 (17%)
Query: 12 RNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAP 71
R ++ + ++ E + E E+++ RR ++ E +KK + + E E
Sbjct: 77 RKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKE---- 132
Query: 72 GSGPVDLFRELLEEGKGVIRGNKEYEEEKRQ-EKERQEKALGILTYLGQSAAEAQTQPPW 130
RE EE K R +E ++E+R+ E+ER+E+ +G+ E + +
Sbjct: 133 --------RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKER- 183
Query: 131 YQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRP 190
++ K R +E +K +K + E + RK+KE +K+R
Sbjct: 184 -----------------KERKKRERNRKERKKERERKERR---ERKKERKKKEERKKERQ 223
Query: 191 KEPPSLDQLRAERLRREAAERSR 213
K+ + + ER +RE ER +
Sbjct: 224 KDRQT-NWREKERGKRERKERKK 245
Score = 37.0 bits (84), Expect = 0.018
Identities = 26/112 (23%), Positives = 54/112 (48%), Gaps = 6/112 (5%)
Query: 148 EKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAERLRRE 207
E+ R RE +K K+ + + R +KEK+G +R KE + R E+ +E
Sbjct: 54 ERESERKKERREREKR--KREREKERKRERGKKEKKG---ERKKEERERKKRRREKENKE 108
Query: 208 AAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPRQQD 259
E+ + + + +GR +EG+ E + ++R+R + + R ++++
Sbjct: 109 GEEKEKRKKKEKKERGRTSKEGK-ERERKEERKREERKERERKKEEREKERE 159
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 48.5 bits (114), Expect = 6e-06
Identities = 47/239 (19%), Positives = 101/239 (42%), Gaps = 28/239 (11%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFR 80
+++E R+EEK +ER + +QE + +K R Q + + +
Sbjct: 285 QQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQ--------E 336
Query: 81 ELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGP 140
E++ E + IR +E E+ + +E++EK Q + Q W Q
Sbjct: 337 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ-------- 388
Query: 141 PPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLR 200
+EKI+ + + +RE ++ + ++ + G++ + +++E ++Q K R
Sbjct: 389 ------EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEK------MRR 436
Query: 201 AERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPRQQD 259
E RE ++ R + R Q +QE + + E + + ++ Q + RQ++
Sbjct: 437 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEE 495
Score = 48.1 bits (113), Expect = 8e-06
Identities = 43/219 (19%), Positives = 100/219 (45%), Gaps = 26/219 (11%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFR 80
R++E + RE+EK +E+ + +QE + +K R Q + + + + G +
Sbjct: 366 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEE 425
Query: 81 ELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGP 140
E+ E+ + + R ++ E++++ +E++EK + Q Q + G
Sbjct: 426 EMQEQEEKMRRQEEKIREQEKKIREQEEK--------------IREQEEMMQEQEEKMGE 471
Query: 141 PPG---------PAPDEKIKSRLDPLREMQKHLGKKRQ--HGGDEGSRSRKEKEGSEKQR 189
G +EK++ + + +RE +K + ++ + +E + ++EK ++++
Sbjct: 472 QEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 531
Query: 190 PKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQE 228
E Q + E++RR+ E+ R + + R Q +QE
Sbjct: 532 MCEQEEKMQEQEEKMRRQ-EEKMREQEVRLRQQEEKMQE 569
Score = 42.4 bits (98), Expect = 4e-04
Identities = 49/256 (19%), Positives = 110/256 (42%), Gaps = 22/256 (8%)
Query: 11 VRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGA 70
+R ++ R R++E +EEK R + ++ ++E + L +K Q + E E
Sbjct: 311 IREQEEKMR-RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 369
Query: 71 PGSGPVDLFRELLEEGKGVIRGNKEY-EEEKRQEKERQEKALGILTYLGQSAAEAQTQPP 129
++ E+ K + K + +EEK +E+E + + + + Q +
Sbjct: 370 ---------EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Query: 130 WYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQR 189
W Q + +EKI+ + +RE ++ + ++ +E + ++EK G ++ +
Sbjct: 421 WEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ-----EEMMQEQEEKMGEQEGK 475
Query: 190 PKEPPSLDQLRAERLRR------EAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRY 243
E + Q + E++RR E ++ R + R Q +QE + + E +++
Sbjct: 476 MCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 535
Query: 244 NSQFNPQLARRPRQQD 259
+ Q + RQ++
Sbjct: 536 EEKMQEQEEKMRRQEE 551
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 48.1 bits (113), Expect = 8e-06
Identities = 58/245 (23%), Positives = 108/245 (44%), Gaps = 35/245 (14%)
Query: 33 ERERRVLLAQQEARTEFLRKKA----RHQNSLPELEAAEAGAPGSGPVDLFRELLEEGKG 88
E + + A+ R + R +A + +S P+ A+ G + REL+
Sbjct: 470 EVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPE 529
Query: 89 VIRGNKEYEEEKRQEK----ERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPP--P 142
+ +++EE KR+E+ E+++ LG + +A E PP + +G PP P
Sbjct: 530 DL--TQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEG---PPSTAI---QGTPPSVP 581
Query: 143 GPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAE 202
G +E + + + E+ + G K G D G+ + +EK+ E+++ +E AE
Sbjct: 582 GLGQEEHVMKEKELVPEVPEEQGSK-DRGLDSGAETEEEKDTWEEKKQRE--------AE 632
Query: 203 RL--RREAAERSRAEA---LLARVQGRALQEGQPEEDETDDRRRR---YNSQFNPQLARR 254
RL R EA E S E ++ + + ++E P ++E +D + Y L
Sbjct: 633 RLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVT 692
Query: 255 PRQQD 259
PR ++
Sbjct: 693 PRSRE 697
Score = 28.9 bits (63), Expect = 4.8
Identities = 40/239 (16%), Positives = 97/239 (40%), Gaps = 51/239 (21%)
Query: 6 KKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEA 65
+K + KD + + ++++ E++ RVL +++ E + KA Q ++ +
Sbjct: 1452 EKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEE--KDKALDQ----KVRS 1505
Query: 66 AEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTY-LGQSAAEA 124
E AP ++ LE+ + +E+K + E++++AL + LGQ
Sbjct: 1506 VEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQK---- 1561
Query: 125 QTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEG 184
DE ++ + L +E ++++++
Sbjct: 1562 ----------------------DEALEQNIQAL---------------EENHQTQEQESL 1584
Query: 185 SEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRY 243
++ + ++P L++ E+++ A + EALL + + L+E +E ++ +Y
Sbjct: 1585 VQEDKTRKPKMLEEKSPEKVK---AMEEKLEALLEKTKALGLEESLVQEGRAREQEEKY 1640
Score = 28.1 bits (61), Expect = 8.2
Identities = 24/105 (22%), Positives = 43/105 (40%), Gaps = 8/105 (7%)
Query: 140 PPPGPAPDEKIKSRLDPLREMQKH------LGKKRQHGGDEGSRSRKEKEGSEKQRPKEP 193
PP PA E++K+ + +K +GKK +K+KE E ++ ++
Sbjct: 370 PPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKE 429
Query: 194 PSLDQLRAERLRREAAERSRAEAL--LARVQGRALQEGQPEEDET 236
D+ R E + E R + L ++ L+ PE +T
Sbjct: 430 LKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKT 474
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 47.4 bits (111), Expect = 1e-05
Identities = 48/216 (22%), Positives = 89/216 (41%), Gaps = 15/216 (6%)
Query: 26 QAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFRELLEE 85
+ +E E E + ++ +TE L + + E +A G GP EE
Sbjct: 602 EEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEE 661
Query: 86 GKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPPPGPA 145
G G + +++E+R EK ++K G + G+ E + W + G
Sbjct: 662 GSS---GAEHWQDEER-EKGEKDKGRGEMERPGEGEKELAEKEEWKKRD--------GEE 709
Query: 146 PDEKIKSR-LDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAERL 204
++K + + R + G + +HG E +E+E ++ KE +++ ER
Sbjct: 710 QEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGER- 768
Query: 205 RREAAERSRAEALLARVQGRAL-QEGQPEEDETDDR 239
+E ER + E +G +G+ EE+ET+ R
Sbjct: 769 EKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGR 804
Score = 35.0 bits (79), Expect = 0.067
Identities = 57/244 (23%), Positives = 92/244 (37%), Gaps = 26/244 (10%)
Query: 23 DEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFREL 82
+E + EEE E E + E E + + E E E G G + E
Sbjct: 838 EEGEGEEEEGEGEEEEGEGKGEEEGE--EGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEG 895
Query: 83 LEE---GKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGG 139
EE G+G G E EEE+ + K +E G G+ E G G
Sbjct: 896 EEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEG----EGEGEEE-----------EGEGE 940
Query: 140 PPPGPAPDEKIKSRLDPLREMQKHLGKKRQHG-GDEGSRSRKEKEG---SEKQRPKEPPS 195
G E+ + + E + G++ G G+EG +E+EG E++ +E
Sbjct: 941 GEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGE 1000
Query: 196 LDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRP 255
+ E E E E + V+G EG+ EE+E ++ + + RR
Sbjct: 1001 EEGEGEEEGEGEGEEEEEGE-VEGEVEGEE-GEGEGEEEEGEEEGEEREKEGEGEENRRN 1058
Query: 256 RQQD 259
R+++
Sbjct: 1059 REEE 1062
Score = 33.1 bits (74), Expect = 0.26
Identities = 43/194 (22%), Positives = 79/194 (40%), Gaps = 26/194 (13%)
Query: 23 DEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFREL 82
+E + + EE+ E ++E E + + E E E G G + E
Sbjct: 915 EEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEG 974
Query: 83 LEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPPP 142
EEG+G G +E E + +E+E +E+ G+ E + + G G
Sbjct: 975 -EEGEG--EGEEEEGEGEGEEEEGEEE--------GEEEGEGEEEGE------GEG---- 1013
Query: 143 GPAPDEKIKSRLDPLREMQKHLGK-KRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRA 201
+E+ + ++ E ++ G+ + + G +EG KE EG E +R +E ++ +
Sbjct: 1014 ----EEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKY 1069
Query: 202 ERLRREAAERSRAE 215
+ E ER E
Sbjct: 1070 QETGEEENERQDGE 1083
Score = 28.9 bits (63), Expect = 4.8
Identities = 49/218 (22%), Positives = 84/218 (38%), Gaps = 17/218 (7%)
Query: 24 EAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFRELL 83
E +EE K+R+ Q++ E +K R+Q + E E G D E
Sbjct: 695 ELAEKEEWKKRDGE---EQEQKEREQGHQKERNQE-MEEGGEEEHGEGEEEEGDREEEEE 750
Query: 84 EEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPPPG 143
+EG+G G E E +R+++E + K + E + GRG
Sbjct: 751 KEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRG----- 805
Query: 144 PAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPP----SLDQL 199
+EK + E+++ G +R+ +EG +E EG E++ E ++
Sbjct: 806 ---EEKEEGGEVEGGEVEEGKG-EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEE 861
Query: 200 RAERLRREAAERSRAEALLARVQGRALQEGQPEEDETD 237
E E E E +G +EG+ E +E +
Sbjct: 862 GEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEE 899
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 47.4 bits (111), Expect = 1e-05
Identities = 60/252 (23%), Positives = 102/252 (40%), Gaps = 23/252 (9%)
Query: 11 VRNKDNVARVRRDEAQAREEEKERERRV--LLAQQEARTEFLRKKAR---HQNSLPELEA 65
V ++ + R + A+ +E+E+E ERR Q +AR E+ R+K R ++S E +
Sbjct: 97 VHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDR 156
Query: 66 AEAGAPGSGPVDLFRELLEEGKGVIRGNKEYE---EEKRQEKERQEKALGILTYLGQSAA 122
E RE +E R KE E EE+R+E+E + + + + +
Sbjct: 157 LEQLERKRERERKMREQQKEQ----REQKERERRAEERRKEREARREVSAHHRTMREDYS 212
Query: 123 EAQTQPPWYQLPPG------RGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGS 176
+ W + PP G P +EK++ R D L ++Q +R+ E S
Sbjct: 213 DKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER-DLLSDLQDISDSERKTSSAESS 271
Query: 177 R----SRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPE 232
S E+E E++ +E S + E E E + ++ +E E
Sbjct: 272 SAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEE 331
Query: 233 EDETDDRRRRYN 244
E D+ R N
Sbjct: 332 EMSEDEERENEN 343
Score = 43.5 bits (101), Expect = 2e-04
Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 11/119 (9%)
Query: 140 PPPGPAPDEKIKSRLDPLREMQKHL---GKKRQHGGDEGSRSRKEKEGSEKQRPK-EPPS 195
PP + EK+ R D R+ +KH K+R+H + R ++K E +R K +
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMA 146
Query: 196 LDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARR 254
+ R ER R E ER R + R ++E Q E+ E +R RR + + ARR
Sbjct: 147 REHSRRERDRLEQLERKRE-------RERKMREQQKEQREQKERERRAEERRKEREARR 198
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 47.4 bits (111), Expect = 1e-05
Identities = 60/252 (23%), Positives = 102/252 (40%), Gaps = 23/252 (9%)
Query: 11 VRNKDNVARVRRDEAQAREEEKERERRV--LLAQQEARTEFLRKKAR---HQNSLPELEA 65
V ++ + R + A+ +E+E+E ERR Q +AR E+ R+K R ++S E +
Sbjct: 63 VHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDR 122
Query: 66 AEAGAPGSGPVDLFRELLEEGKGVIRGNKEYE---EEKRQEKERQEKALGILTYLGQSAA 122
E RE +E R KE E EE+R+E+E + + + + +
Sbjct: 123 LEQLERKRERERKMREQQKEQ----REQKERERRAEERRKEREARREVSAHHRTMREDYS 178
Query: 123 EAQTQPPWYQLPPG------RGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGS 176
+ W + PP G P +EK++ R D L ++Q +R+ E S
Sbjct: 179 DKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER-DLLSDLQDISDSERKTSSAESS 237
Query: 177 R----SRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPE 232
S E+E E++ +E S + E E E + ++ +E E
Sbjct: 238 SAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEE 297
Query: 233 EDETDDRRRRYN 244
E D+ R N
Sbjct: 298 EMSEDEERENEN 309
Score = 43.5 bits (101), Expect = 2e-04
Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 11/119 (9%)
Query: 140 PPPGPAPDEKIKSRLDPLREMQKHL---GKKRQHGGDEGSRSRKEKEGSEKQRPK-EPPS 195
PP + EK+ R D R+ +KH K+R+H + R ++K E +R K +
Sbjct: 53 PPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMA 112
Query: 196 LDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARR 254
+ R ER R E ER R + R ++E Q E+ E +R RR + + ARR
Sbjct: 113 REHSRRERDRLEQLERKRE-------RERKMREQQKEQREQKERERRAEERRKEREARR 164
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 46.6 bits (109), Expect = 2e-05
Identities = 60/258 (23%), Positives = 102/258 (39%), Gaps = 47/258 (18%)
Query: 12 RNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAP 71
R KD + R + R+ EKERER Q + + R+K R++ E E G
Sbjct: 83 REKDRHRKRDRHRERQRDREKERER-----QTDRERDRQREKERNRQKERERETEREGER 137
Query: 72 GSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWY 131
G R+ +G+ +E E ++ EKER+ Q+ E Q Q
Sbjct: 138 G-------RDRQTDGQ------RERERQRDAEKERER----------QTDRERQRQT--- 171
Query: 132 QLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHG--GDEGSRSRKEKEGSEKQR 189
++ + R + R+ +K + +H G E R R+ + +E++R
Sbjct: 172 -----ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226
Query: 190 PKEPPSLDQLRAERLRREAAERSRA---------EALLARVQGRALQEGQPEEDETDDRR 240
+ Q + ER R + AER RA E R + R Q E + DR+
Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286
Query: 241 RRYNSQFNPQLARRPRQQ 258
R+ ++ + + R+ +Q
Sbjct: 287 RQRRTERDRETERKRERQ 304
Score = 40.4 bits (93), Expect = 0.002
Identities = 52/247 (21%), Positives = 94/247 (38%), Gaps = 42/247 (17%)
Query: 22 RDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFRE 81
R+ + +E E+ RE+R + + + E R+K RH+ D RE
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRKR-----------------DRHRE 96
Query: 82 LLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPP 141
+ + + E ++++EKER Q E +T+ + GR
Sbjct: 97 RQRDREKERERQTDRERDRQREKERNR----------QKERERETEREGER---GRDRQT 143
Query: 142 PGPAPDEKIKSRLDPLREMQKHLGKKRQHGGD-------EGSRSRKEKEGSEKQRPKEPP 194
G E+ + D +E ++ ++RQ + E ++R+E+ E+QR KE
Sbjct: 144 DGQRERERQR---DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
Query: 195 SLDQ--LRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLA 252
+ D+ R RE + E + R Q E E R R + + +
Sbjct: 201 TEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDK 260
Query: 253 RRPRQQD 259
R R++D
Sbjct: 261 ERERERD 267
Score = 40.0 bits (92), Expect = 0.002
Identities = 52/267 (19%), Positives = 109/267 (40%), Gaps = 29/267 (10%)
Query: 12 RNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNS------------ 59
R +D +R+ + R+ EKERER+ +++ +TE R+K R +
Sbjct: 137 RGRDRQTDGQRERERQRDAEKERERQT-DRERQRQTERNRQKEREREKNRQERRERERQR 195
Query: 60 LPELEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQ 119
E + + + + RE E + + ++E + +++ E+ER+++A +
Sbjct: 196 EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQA------ERE 249
Query: 120 SAAEAQTQPPWYQ-------LPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGG 172
A+E +T+ + R D K + R + RE ++ ++R+
Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRER-- 307
Query: 173 DEGSRSRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPE 232
E R R K E++R +E + +R + +R R + + +EG+ +
Sbjct: 308 -ERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQ 366
Query: 233 EDETDDRRRRYNSQFNPQLARRPRQQD 259
+ +R R + Q + R R +D
Sbjct: 367 AERERERERERDRQSAREREERERDRD 393
Score = 36.2 bits (82), Expect = 0.030
Identities = 54/249 (21%), Positives = 95/249 (38%), Gaps = 29/249 (11%)
Query: 12 RNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAP 71
R + + RD+ + RE +++R+R ++E +T+ RK+ R E E
Sbjct: 248 RERASERETERDKERERERDRDRDRDRRQKERERQTD--RKRQRRTERDRETERKRE--- 302
Query: 72 GSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWY 131
R+ E + +E E E+ +E+ERQ + + + QT+
Sbjct: 303 --------RQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTE---M 351
Query: 132 QLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPK 191
R G E+ + R RE + ++R +E R R E++R
Sbjct: 352 DRERNRQTGREGRRQAERERERE---RERDRQSARER----EERERDRDRDRQKERERQT 404
Query: 192 EPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQL 251
E Q E+ R +R E+ R +GR E + ++ DR R+ + Q Q
Sbjct: 405 EKDRDGQRETEKQREREKDR---ESERGRERGR---EREKQKGRERDRERQTDRQAGRQR 458
Query: 252 ARRPRQQDP 260
R +P
Sbjct: 459 KRSTLYVNP 467
Score = 35.0 bits (79), Expect = 0.067
Identities = 43/223 (19%), Positives = 78/223 (34%), Gaps = 45/223 (20%)
Query: 12 RNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAP 71
R ++ R+ + RE E+ERER + R + +K + Q + + G
Sbjct: 303 RQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGRE 362
Query: 72 GSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWY 131
G + RE E R + EE+ ++++R Q E QT+
Sbjct: 363 GRRQAERERERERERD---RQSAREREERERDRDRDR----------QKERERQTE---- 405
Query: 132 QLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPK 191
D + + RE +K +R G E R R++++G E+ R +
Sbjct: 406 --------------KDRDGQRETEKQREREKDRESER---GRERGREREKQKGRERDRER 448
Query: 192 EPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEED 234
+ R+A + + L R + G + D
Sbjct: 449 QTD-----------RQAGRQRKRSTLYVNPPPRTARSGVVQSD 480
Score = 32.7 bits (73), Expect = 0.33
Identities = 48/200 (24%), Positives = 74/200 (37%), Gaps = 49/200 (24%)
Query: 12 RNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEA-AEAGA 70
RN+ RR + RE E+ER+R Q AR R++ R ++ E E E
Sbjct: 355 RNRQTGREGRRQAERERERERERDR------QSAREREERERDRDRDRQKERERQTEKDR 408
Query: 71 PGSGPVDLFREL---LEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQ 127
G + RE E +G RG +E E++K +E++R+ + + A + +
Sbjct: 409 DGQRETEKQREREKDRESERGRERG-REREKQKGRERDRERQT-------DRQAGRQRKR 460
Query: 128 PPWYQLPPGRGGPP------------------------------PGPAPDEKIKSRLDPL 157
Y PP R P P + + R+
Sbjct: 461 STLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGR 520
Query: 158 REMQKHLGKKRQHGGDEGSR 177
R + LG+KR GG EG R
Sbjct: 521 RRWEPRLGEKRGQGG-EGRR 539
Score = 30.4 bits (67), Expect = 1.7
Identities = 26/114 (22%), Positives = 48/114 (42%), Gaps = 13/114 (11%)
Query: 6 KKSWHVRNKDNVARVRRDEAQAREEEKERERRVLL-------------AQQEARTEFLRK 52
+K R ++ +R+ + RE+E+ER+R+ +++A E R+
Sbjct: 315 RKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE 374
Query: 53 KARHQNSLPELEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKER 106
+ R + S E E E + R+ ++ G K+ E EK +E ER
Sbjct: 375 RERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESER 428
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 46.2 bits (108), Expect = 3e-05
Identities = 59/274 (21%), Positives = 109/274 (39%), Gaps = 44/274 (16%)
Query: 11 VRNKDNVARVRRDEAQAREEEK----ERERRVLL----------------AQQEARTEFL 50
++ ++ A R A+A EEEK E++R L +Q+ +++
Sbjct: 359 IKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWV 418
Query: 51 RKKARHQNSLPELEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKA 110
+K ++ L + G V RE L+E K + + +E+ +++KE +E+
Sbjct: 419 NEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEV 478
Query: 111 LGIL------TYLGQSAAEAQTQP-----PWYQLPPGRGGPPPGPA---PDEKIKSRLDP 156
+ T + E T + P GR A P + RL+
Sbjct: 479 KSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEE 538
Query: 157 LREMQ--------KHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAERLRREA 208
LR + + L +K+Q E +K++E K +E Q A+R RE
Sbjct: 539 LRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREE 598
Query: 209 AERSRAEALLARVQGRALQEGQ--PEEDETDDRR 240
E+ R + + R + A ++ Q PE+ +DD++
Sbjct: 599 EEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 632
Score = 37.0 bits (84), Expect = 0.018
Identities = 54/242 (22%), Positives = 101/242 (41%), Gaps = 46/242 (19%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFR 80
RR+E + + ++ ER+ R QN E E E + +
Sbjct: 102 RREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYE 161
Query: 81 ELLEEGKGVIRGN-----KEYEEEKRQEKERQEK--------ALG---ILTYLGQSAAEA 124
+EE + V + ++ EE K+++KE++E+ ++G + + + E+
Sbjct: 162 --IEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTES 219
Query: 125 QTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRK---- 180
Q + L G+ S +P +E ++R+ G DE S K
Sbjct: 220 QEETVVMSLKNGQ-------------ISSEEPKQE------EEREQGSDEISHHEKMEEE 260
Query: 181 EKEGSEKQRPK-EPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDR 239
+KE +E +R + E ++++AE+ ++ A ER+R EA + A QE + E E +R
Sbjct: 261 DKERAEAERARLEAEERERIKAEQDKKIADERARIEA----EEKAAAQERERREAEERER 316
Query: 240 RR 241
R
Sbjct: 317 MR 318
Score = 34.7 bits (78), Expect = 0.088
Identities = 52/272 (19%), Positives = 103/272 (37%), Gaps = 29/272 (10%)
Query: 7 KSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQN-------- 58
KS+ + + ++++ + EEE+E+ +R + + + K Q
Sbjct: 170 KSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLK 229
Query: 59 ----SLPELEAAEAGAPGSGPVDLFRELLEEGKG---VIRGNKEYEEEKRQEKERQEKAL 111
S E + E GS + ++ EE K R E EE +R + E+ +K
Sbjct: 230 NGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIA 289
Query: 112 GILTYL-GQSAAEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQH 170
+ + A AQ + R A +E+ + ++E +K ++RQ
Sbjct: 290 DERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQR-----IKEEEKRAAEERQR 344
Query: 171 GGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQ 230
+E R+ E+QR KE +R R E E+++ E + + + L+E +
Sbjct: 345 IKEEEKRA-----AEERQRIKEEEKRAAEERQRARAEEEEKAKVE---EQKRNKQLEEKK 396
Query: 231 PEEDETDDRRRRYNSQFNPQLARRPRQQDPHL 262
ET + + + + + Q+ L
Sbjct: 397 HAMQETKIKGEKVEQKIEGKWVNEKKAQEDKL 428
>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
Length = 273
Score = 46.2 bits (108), Expect = 3e-05
Identities = 53/235 (22%), Positives = 101/235 (42%), Gaps = 15/235 (6%)
Query: 7 KSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAA 66
+S H ++ + + R +++R++E+ R+R + R R ++R N+
Sbjct: 11 RSKHTKSSKHNKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNTAVSRRER 70
Query: 67 EAGAPGSGP--VDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEA 124
+ S P +D+F + + + K EEEK+ E ERQ K + + E
Sbjct: 71 DRERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIR--QQEIEEKLIEE 128
Query: 125 QTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEG 184
+T +L R DE + L + E ++ + K+ +E R R+ +
Sbjct: 129 ETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLL---EELERQRQAELA 185
Query: 185 SEKQRPKEPPSLDQLRAERLRREAAERSR----AEALLARVQGRALQEGQPEEDE 235
++K R +E ++ + E L R E +R A+A LA Q R ++E + +E
Sbjct: 186 AQKAREEE----ERAKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKIHEE 236
Score = 34.7 bits (78), Expect = 0.088
Identities = 32/110 (29%), Positives = 51/110 (46%), Gaps = 9/110 (8%)
Query: 12 RNKDNVAR--VRRDEAQAREEEK------ERERRVLLAQQEARTEFLRKKARHQNSLPEL 63
+ KD + R +RR E R EK ER+R+ LA Q+AR E R K + E
Sbjct: 148 KRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEE 207
Query: 64 EAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEK-RQEKERQEKALG 112
+ + + ++EE + + + E+E+ RQ+KE Q+ LG
Sbjct: 208 NNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQQKEEQKIILG 257
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 45.8 bits (107), Expect = 4e-05
Identities = 54/273 (19%), Positives = 110/273 (40%), Gaps = 55/273 (20%)
Query: 9 WHVRNK--DNVARVRRDEAQA-REEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEA 65
W + K + ++R+ E + R+EEK RE+ + +QE + +K R Q
Sbjct: 492 WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQE------- 544
Query: 66 AEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKE----RQEKALGILTYLGQSA 121
E+ E + + K +EEEKRQE+E RQE+ +
Sbjct: 545 ---------------EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKI---------- 579
Query: 122 AEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKE 181
Q + W Q R +EK+ + + +RE ++ + ++ + ++ + R++
Sbjct: 580 -REQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ 638
Query: 182 KEGSEKQRPKEPPSLDQL---------------RAERLRREAAERSRAEALLARVQGRAL 226
+E +++Q K +++ R E RE ++ R + R Q +
Sbjct: 639 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMM 698
Query: 227 QEGQPEEDETDDRRRRYNSQFNPQLARRPRQQD 259
QE + + E +++ + Q + RQ++
Sbjct: 699 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 731
Score = 41.6 bits (96), Expect = 7e-04
Identities = 46/242 (19%), Positives = 102/242 (42%), Gaps = 31/242 (12%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFR 80
R++E + RE+EK +E+ + +QE + +K R Q +
Sbjct: 413 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE---------------------K 451
Query: 81 ELLEEGKGVIRGNKEYEEEKRQEKE---RQEKALGILTYLGQSAAEAQTQPPWYQLPPGR 137
++ + + + K EEEKRQE+E RQE+ + Q Q + Q R
Sbjct: 452 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH-----EQEEIWRQKEKMHEQEEKIR 506
Query: 138 GGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLD 197
+EKI+ + + +RE ++ + ++ + ++ R+E++ E+++ E
Sbjct: 507 KQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ 566
Query: 198 QLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPRQ 257
+ + R+E R + E + Q ++E + + E +++ + + Q + Q
Sbjct: 567 EQEDKMWRQEEKIREQEEKVWR--QEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQ 624
Query: 258 QD 259
++
Sbjct: 625 EE 626
Score = 38.5 bits (88), Expect = 0.006
Identities = 31/181 (17%), Positives = 80/181 (44%), Gaps = 22/181 (12%)
Query: 6 KKSWHVRNKDNVARVRRDEAQAR---EEEKERERRVLLAQQEARTEFLRKKARHQNSLPE 62
+K W K +R E + + +EEK RE+ + +QE + +K R Q + +
Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 63 LEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAA 122
+ + G + ++ E+ + + R ++ E++++ +E++EK +
Sbjct: 644 EQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIRE-----QEEMM 698
Query: 123 EAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEK 182
+ Q + W Q +EK+ + + ++E ++ + ++ + ++ R R+++
Sbjct: 699 QEQEEKMWEQ--------------EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 744
Query: 183 E 183
E
Sbjct: 745 E 745
Score = 37.7 bits (86), Expect = 0.010
Identities = 48/253 (18%), Positives = 99/253 (39%), Gaps = 28/253 (11%)
Query: 7 KSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELE-- 64
+ W + ++ ++R E + RE+E++ R Q+E E K R + + E E
Sbjct: 310 QEWEEKIQEQEEKIREQEEKIREQEEKMRR-----QEEMMWEKEEKMRRQEEMMWEKEEK 364
Query: 65 ---AAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSA 121
E + E++ E + IR +E E+ + +E++EK Q
Sbjct: 365 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 424
Query: 122 AEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDE----GSR 177
+ Q W Q +EKI+ + + +RE +K + ++ + ++
Sbjct: 425 RQEQEAKMWRQ--------------EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 470
Query: 178 SRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETD 237
R+E+E +Q K + R + E E+ R + Q ++E + + E +
Sbjct: 471 KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE 530
Query: 238 DRRRRYNSQFNPQ 250
++ R + Q
Sbjct: 531 EKMWRQEEKIREQ 543
Score = 36.6 bits (83), Expect = 0.023
Identities = 44/246 (17%), Positives = 109/246 (44%), Gaps = 29/246 (11%)
Query: 21 RRDEAQA---REEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVD 77
+R E +A R+EEK RE+ + +QE + +K Q + E E + +
Sbjct: 424 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE------QEE 477
Query: 78 LFR--ELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAE--AQTQPPWYQL 133
++R E + E + + R ++ E++ + ++++EK + + + Q + W Q
Sbjct: 478 MWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQ- 536
Query: 134 PPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEP 193
+EKI+ + + RE +K + ++ + +E + +++K ++++ +E
Sbjct: 537 -------------EEKIREQEEMWREEEK-MHEQEKIWEEEKRQEQEDKMWRQEEKIREQ 582
Query: 194 PSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLAR 253
+ E++R + +R E + + Q ++E + + E +++ R + Q
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWK-QEEKIREQEEKIQEQEEKIREQEEKIREQEEM 641
Query: 254 RPRQQD 259
Q++
Sbjct: 642 TQEQEE 647
Score = 34.3 bits (77), Expect = 0.11
Identities = 37/213 (17%), Positives = 91/213 (42%), Gaps = 23/213 (10%)
Query: 6 KKSWHV-RNKDNVARVRRDEAQAREEEKE--RERRVLLAQQEARTEFLRKKARHQNSLPE 62
+K W + ++ ++ R E + RE+E++ R+ + Q+E R E K + + + E
Sbjct: 557 EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIRE 616
Query: 63 LEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAA 122
E + E + E + IR +E +E+ ++ QE+ + +
Sbjct: 617 QEEK---------IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM----CEQEEKM 663
Query: 123 EAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEK 182
+ Q + W Q R ++KI+ + + +RE ++ + ++ + ++ + +++
Sbjct: 664 QEQEETMWRQEEKIR-------EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 716
Query: 183 EGSEKQRPKEPPSLDQLRAERLRREAAERSRAE 215
E ++Q K +++ + +R E E
Sbjct: 717 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 33.9 bits (76), Expect = 0.15
Identities = 38/226 (16%), Positives = 94/226 (41%), Gaps = 34/226 (15%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFR 80
+++E R+EEK +E + +QE + +K R Q +
Sbjct: 297 QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ---------------E 341
Query: 81 ELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGP 140
E++ E + +R +E EK ++ RQE+ + + + Q + W +
Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRQEE----MMWEKEEKMRRQEEMMWEK-------- 389
Query: 141 PPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLR 200
+EKI+ + + E +K ++ + +E R +++++ E + ++ + + +
Sbjct: 390 ------EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE-Q 442
Query: 201 AERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQ 246
E++R + + R E + + +E + E++E + + + Q
Sbjct: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQ 488
Score = 30.8 bits (68), Expect = 1.3
Identities = 41/228 (17%), Positives = 94/228 (41%), Gaps = 49/228 (21%)
Query: 9 WHVRNKDNVARVRRDEAQARE-EEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAE 67
W+ N+ ++ R E + +E EEK +E+ + +QE + +K R Q
Sbjct: 291 WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE--------- 341
Query: 68 AGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQ 127
E++ E + +R +E EK ++ RQE+ + + + Q +
Sbjct: 342 -------------EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM----WEKEEKMRRQEE 384
Query: 128 PPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEK 187
W + +EKI RE+++ + ++ + E R +EK ++
Sbjct: 385 MMWEK--------------EEKI-------RELEEKMHEQEKIREQEEKRQEEEKIREQE 423
Query: 188 QRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDE 235
+R ++ + + + E++R + + E + R + + ++ + E+E
Sbjct: 424 KRQEQEAKMWR-QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 470
>gi|41054864 regulating synaptic membrane exocytosis 1 [Homo
sapiens]
Length = 1692
Score = 45.8 bits (107), Expect = 4e-05
Identities = 55/200 (27%), Positives = 88/200 (44%), Gaps = 21/200 (10%)
Query: 72 GSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWY 131
GSGP ++ G++ E+K + +ER T L +AA +Q P
Sbjct: 181 GSGPQQTSQDGTLSDTATGAGSEVPREKKARLQERSRSQ----TPLSTAAASSQDAAP-P 235
Query: 132 QLPPGR--GGPPPGPA--PDEK---IKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEG 184
PP R G P A P++K +SR +P RE +K G Q+ G +S +++
Sbjct: 236 SAPPDRSKGAEPSQQALGPEQKQASSRSRSEPPRERKKTPGLSEQN-GKGALKSERKRVP 294
Query: 185 SEKQRPKEPPSLDQLRAERLRREAAERSRA----EALLARVQGRALQEGQPEEDETDDRR 240
+P E ++ R ER E+ R+ + R +G+A E + ++E D +
Sbjct: 295 KTSAQPVEGAVEERERKERRESRRLEKGRSQDYPDTPEKRDEGKAADEEKQRKEE--DYQ 352
Query: 241 RRYNSQFNPQLARRPRQQDP 260
RY S +P LAR P + P
Sbjct: 353 TRYRS--DPNLARYPVKPPP 370
Score = 29.6 bits (65), Expect = 2.8
Identities = 52/223 (23%), Positives = 75/223 (33%), Gaps = 43/223 (19%)
Query: 21 RRDEAQAREEEKERERRVLLA------------------QQEARTEFLRKKARHQ--NSL 60
+RDE +A +EEK+R+ +Q+ R +ARH+ +S
Sbjct: 333 KRDEGKAADEEKQRKEEDYQTRYRSDPNLARYPVKPPPEEQQMRMHARVSRARHERRHSD 392
Query: 61 PELEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQS 120
L EAGA L EGK K R +A ++
Sbjct: 393 VALPRTEAGA-----------ALPEGK----AGKRAPAAARASPPDSPRAYS-AERTAET 436
Query: 121 AAEAQTQPPWYQLPPGRGGPPPGPAPDEKI------KSRLDPLREMQKHLGKKRQHGGDE 174
A Q + P R GP P AP+ K +SRLDP + KR+
Sbjct: 437 RAPGAKQLTNHSPPAPRHGPVPAEAPELKAQEPLRKQSRLDPSSAVLMRKA-KREKVETM 495
Query: 175 GSRSRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEAL 217
+ SE RP P R + R+ + S E +
Sbjct: 496 LRNDSLSSDQSESVRPSPPKPHRSKRGGKKRQMSVSSSEEEGV 538
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 45.4 bits (106), Expect = 5e-05
Identities = 51/250 (20%), Positives = 112/250 (44%), Gaps = 34/250 (13%)
Query: 21 RRDEAQA---REEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVD 77
+R E +A R+EEK RE+ + +QE + +K Q + E E + +
Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 530
Query: 78 LFRELLEEGKGVIRGNKEYEEEKRQEKE--RQEKALGILTYLGQSAAEAQTQPPWYQLPP 135
RE E + + +++ E+ ++QE++ RQE+ + + + Q + W Q
Sbjct: 531 KIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKM----HDQEEKIREQEEKVWRQ--- 583
Query: 136 GRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPS 195
+EKI+ + + +RE ++ + ++ +E ++ ++EK G ++++ E
Sbjct: 584 -----------EEKIREQEEKIREQEEKIREQ-----EEMTQEQEEKMGEQEEKMCEQEE 627
Query: 196 LDQLRAERLR------REAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNP 249
Q + E++R RE ++ R + R Q +QE + + E +++ +
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687
Query: 250 QLARRPRQQD 259
Q + RQ++
Sbjct: 688 QEEKMRRQEE 697
Score = 36.6 bits (83), Expect = 0.023
Identities = 33/187 (17%), Positives = 84/187 (44%), Gaps = 29/187 (15%)
Query: 6 KKSWHVRNK--DNVARVRRDEAQA-REEEKERERRVLLAQQEARTEFLRKKARHQNSLPE 62
+K W K D ++R E + R+EEK RE+ + +QE +K R Q + +
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE-------EKIREQEEMTQ 609
Query: 63 LEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAA 122
+ + G + ++ E+ + + R ++ E++++ +E++EK +
Sbjct: 610 EQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE-----QEEMM 664
Query: 123 EAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEK 182
+ Q + W Q +EK+ + + ++E ++ + ++ + ++ R R+++
Sbjct: 665 QEQEEKMWEQ--------------EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 710
Query: 183 EGSEKQR 189
E ++ +
Sbjct: 711 EKMQEHQ 717
Score = 36.2 bits (82), Expect = 0.030
Identities = 38/188 (20%), Positives = 77/188 (40%), Gaps = 30/188 (15%)
Query: 7 KSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAA 66
+ W + ++ ++R E + RE+E++ R Q+E E K R + + E E
Sbjct: 371 QEWEEKIQEQEEKIREQEEKIREQEEKMRR-----QEEMMWEKEEKMRRQEEMMWEKEE- 424
Query: 67 EAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQT 126
+ E++ E + IR +E E+ + +E++EK Q + Q
Sbjct: 425 --------KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 476
Query: 127 QPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQ--HGGDEGSRSRKEKEG 184
W Q +EKI+ + + +RE ++ + ++ + H ++ K +E
Sbjct: 477 AKMWRQ--------------EEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQ 522
Query: 185 SEKQRPKE 192
E R +E
Sbjct: 523 EEMWRQEE 530
Score = 29.3 bits (64), Expect = 3.7
Identities = 39/221 (17%), Positives = 89/221 (40%), Gaps = 34/221 (15%)
Query: 26 QAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFRELLEE 85
QA+ EE E R+ Q+E K R + + E E E ++E
Sbjct: 343 QAQVEENELWNRLNQQQEE-------KMWRQEEKIQEWE----------------EKIQE 379
Query: 86 GKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPPPGPA 145
+ IR +E E+ ++ RQE+ + + + Q + W + R
Sbjct: 380 QEEKIREQEEKIREQEEKMRRQEEMM----WEKEEKMRRQEEMMWEKEEKMR-------R 428
Query: 146 PDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAERLR 205
+E + + + +RE+++ + ++ + E R +EK +++R ++ + + +
Sbjct: 429 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 488
Query: 206 REAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQ 246
+E R + E + + + QE EE++ ++ + +
Sbjct: 489 QEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 45.1 bits (105), Expect = 6e-05
Identities = 54/246 (21%), Positives = 101/246 (41%), Gaps = 43/246 (17%)
Query: 19 RVRRDEAQAREEEKERER-RVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVD 77
+ R E + +EEE+ RER + + ++E E K + + ++ E E E
Sbjct: 438 KTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ-------- 489
Query: 78 LFRELLEEGKGVIRGNKEYEEEKRQEKER----QEKALGILTYLGQSAAEAQTQPPWYQL 133
++ L E K K +E+EK QE+E QE+ + Q Q + W Q
Sbjct: 490 --QQRLPEQK-----EKLWEQEKMQEQEEKIWEQEEKIR-----DQEEMWGQEKKMWRQ- 536
Query: 134 PPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEP 193
EK++ + D + E ++ + + Q D+ R K+ + EK K
Sbjct: 537 --------------EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEK---KTW 579
Query: 194 PSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLAR 253
+++R E RE ++ R E + R Q +QE + + E +++ + Q +
Sbjct: 580 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK 639
Query: 254 RPRQQD 259
Q++
Sbjct: 640 MWEQEE 645
Score = 43.9 bits (102), Expect = 1e-04
Identities = 53/263 (20%), Positives = 116/263 (44%), Gaps = 31/263 (11%)
Query: 2 NILPKKSWHVRN--KDNVARVRRDEAQA-REEEKERERRVLLAQQEARTEFLRKKARHQN 58
N L ++ W ++ ++R+ E + R+EE+ RE+ + +QE + K+ R Q
Sbjct: 268 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQE 327
Query: 59 SLPELEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLG 118
+EL E+ K +R KE E++ Q +E++EK +
Sbjct: 328 ---------------------KELREQEK-ELREQKELREQEEQMQEQEEKMWEQEEKMR 365
Query: 119 QSAAE--AQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGS 176
+ + Q + W Q R +E++ + + LRE ++ + ++++ ++
Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM-REQEKMWEQVE 424
Query: 177 RSRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDET 236
+ R+EK+ E+++ K ++++ E RE ++ R E R Q +Q + EE+
Sbjct: 425 KMREEKKMQEQEK-KTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQ--KQEENMW 481
Query: 237 DDRRRRYNSQFNPQLARRPRQQD 259
+ + + Q P+ + +Q+
Sbjct: 482 EQEEKEWQQQRLPEQKEKLWEQE 504
Score = 34.7 bits (78), Expect = 0.088
Identities = 42/233 (18%), Positives = 89/233 (38%), Gaps = 60/233 (25%)
Query: 6 KKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEA 65
KK+W D ++R +E E+K RE ++ +QE + + +K + Q
Sbjct: 576 KKTW-----DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQ-------- 622
Query: 66 AEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQ 125
E + E +EEK QE+E + + + Q
Sbjct: 623 --------------EEKMWE-----------QEEKMQEQEEK-------MWEQEEKMWEQ 650
Query: 126 TQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGS 185
+ W Q +++ + + L E +K +++ +E +++ E
Sbjct: 651 EEKMWEQ---------------QRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKK 695
Query: 186 EKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDD 238
+++ K+ +++R E RE ++ R E + R Q +QE + + E ++
Sbjct: 696 TQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 748
>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
sapiens]
Length = 482
Score = 45.1 bits (105), Expect = 6e-05
Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 21/119 (17%)
Query: 24 EAQAREEEK--ERERRVL-----LAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPV 76
E Q EEEK ERER+ L L +Q+A+ EF KK + + + E E
Sbjct: 54 EEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQE--------- 104
Query: 77 DLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPP 135
R+L E+ + R +E EE+KRQEK+ +E+AL + L Q+ E + W P
Sbjct: 105 ---RKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKM--LDQAENELENGTTWQNPEP 158
Score = 30.0 bits (66), Expect = 2.2
Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 4/70 (5%)
Query: 144 PAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAER 203
P+PD K + R+ +H GKK H SR R + R + S D+ R
Sbjct: 383 PSPDHSYKRNGESERKSSRHRGKK-SHKRTSKSRERHNSRSRGRNRDR---SRDRSRGRG 438
Query: 204 LRREAAERSR 213
R + RSR
Sbjct: 439 SRSRSRSRSR 448
>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
Length = 558
Score = 44.7 bits (104), Expect = 8e-05
Identities = 57/272 (20%), Positives = 108/272 (39%), Gaps = 35/272 (12%)
Query: 4 LPKKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFL----RKKARHQNS 59
LP + +N + +++++R+E E E + + + ++ KK +
Sbjct: 126 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 185
Query: 60 LPELEAAEAGAPGSGP-------VDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALG 112
E E + G+ G V RE L+E K + + +E+ +++KE +E+
Sbjct: 186 EEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKS 245
Query: 113 IL------TYLGQSAAEAQTQP-----PWYQLPPGRGGPPPGPA---PDEKIKSRLDPLR 158
+ T + E T + P GR A P + RL+ LR
Sbjct: 246 FMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELR 305
Query: 159 EMQ--------KHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAERLRREAAE 210
+ + L +K+Q E +K++E K +E Q A+R RE E
Sbjct: 306 RRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEE 365
Query: 211 RSRAEALLARVQGRALQEGQ--PEEDETDDRR 240
+ R + + R + A ++ Q PE+ +DD++
Sbjct: 366 KRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 397
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 44.7 bits (104), Expect = 8e-05
Identities = 57/272 (20%), Positives = 108/272 (39%), Gaps = 35/272 (12%)
Query: 4 LPKKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFL----RKKARHQNS 59
LP + +N + +++++R+E E E + + + ++ KK +
Sbjct: 132 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 191
Query: 60 LPELEAAEAGAPGSGP-------VDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALG 112
E E + G+ G V RE L+E K + + +E+ +++KE +E+
Sbjct: 192 EEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKS 251
Query: 113 IL------TYLGQSAAEAQTQP-----PWYQLPPGRGGPPPGPA---PDEKIKSRLDPLR 158
+ T + E T + P GR A P + RL+ LR
Sbjct: 252 FMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELR 311
Query: 159 EMQ--------KHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAERLRREAAE 210
+ + L +K+Q E +K++E K +E Q A+R RE E
Sbjct: 312 RRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEE 371
Query: 211 RSRAEALLARVQGRALQEGQ--PEEDETDDRR 240
+ R + + R + A ++ Q PE+ +DD++
Sbjct: 372 KRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 403
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 44.3 bits (103), Expect = 1e-04
Identities = 52/255 (20%), Positives = 113/255 (44%), Gaps = 28/255 (10%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQ--------NSLPELEAAEAGAPG 72
R++E + RE+EK +E+ + +QE + +K R Q + E E
Sbjct: 399 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 458
Query: 73 SGPVDLFR--ELLEEGKGVIR-GNKEYEEEKRQEKE----RQEKALGILTYLGQSAAEAQ 125
+++R E + E + + R K +E+EK +++E RQE+ + + + Q
Sbjct: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM----HDQEEKIREQ 514
Query: 126 TQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGS 185
+ W Q R +EKI+ + + +RE ++ + ++ + G++ +E+E
Sbjct: 515 EEKMWRQEEKIR-------EQEEKIREQEEKIREQEEMMQEQEEKMGEQ-EEKMQEQEKM 566
Query: 186 EKQRPKEPPSLDQLRAERLR-REAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYN 244
+Q K +++R ++ + RE E+ + R Q +QE + + E +++
Sbjct: 567 RRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 626
Query: 245 SQFNPQLARRPRQQD 259
+ Q + RQ++
Sbjct: 627 EKMQEQEEKMRRQEE 641
Score = 42.7 bits (99), Expect = 3e-04
Identities = 49/271 (18%), Positives = 110/271 (40%), Gaps = 27/271 (9%)
Query: 1 MNILPKKSWHVRNK-DNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNS 59
M L + W K + ++ + RE+E++R+ + +QE R E K R +
Sbjct: 365 MRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 424
Query: 60 LPELEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKE---RQEKALGILTY 116
+ E E + +++ + + + K EEEKRQE+E RQE+ +
Sbjct: 425 IREQEEKIR--------EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 476
Query: 117 L--------GQSAAEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKR 168
+ Q Q + W Q +EKI+ + + + ++ + ++
Sbjct: 477 IWRQKEKMHEQEKIRKQEEKVWRQEEKMHD-------QEEKIREQEEKMWRQEEKIREQE 529
Query: 169 QHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQE 228
+ ++ + R+++E ++Q K ++++ + R E+ R + R Q ++E
Sbjct: 530 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIRE 589
Query: 229 GQPEEDETDDRRRRYNSQFNPQLARRPRQQD 259
+ + E +++ R Q + Q++
Sbjct: 590 QEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
Score = 39.7 bits (91), Expect = 0.003
Identities = 46/256 (17%), Positives = 103/256 (40%), Gaps = 31/256 (12%)
Query: 7 KSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAA 66
+ W + ++ ++R E + RE+E++ R Q+E E K R + + E E
Sbjct: 310 QEWEEKIQEQEEKIREQEEKIREQEEKMRR-----QEEMMWEKEEKMRRQEEMMWEKEE- 363
Query: 67 EAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQT 126
+ E++ E + IR +E E+ + +E++EK Q + Q
Sbjct: 364 --------KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 415
Query: 127 QPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQ--HGGDEGSRSRKEKEG 184
W Q +EKI+ + + +RE +K + ++ + H ++ K +E
Sbjct: 416 AKMWRQ--------------EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQ 461
Query: 185 SEKQRPKEP-PSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRY 243
E R +E +++ ++ + E+ R + Q + + + + E +++ R
Sbjct: 462 EEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQ 521
Query: 244 NSQFNPQLARRPRQQD 259
+ Q + Q++
Sbjct: 522 EEKIREQEEKIREQEE 537
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 44.3 bits (103), Expect = 1e-04
Identities = 51/261 (19%), Positives = 109/261 (41%), Gaps = 47/261 (18%)
Query: 2 NILPKKSWHVRN--KDNVARVRRDEAQA-REEEKERERRVLLAQQEARTEFLRKKARHQN 58
N L ++ W ++ ++R+ E + R+EE+ RE+ + +QE + K+ R Q
Sbjct: 230 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE 289
Query: 59 SLPELEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLG 118
+EL E+ K +R K+ E++ Q +E++EK +
Sbjct: 290 ---------------------KELREQEK-ELREQKKLREQEEQMQEQEEK-----MWEQ 322
Query: 119 QSAAEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRS 178
+ Q + W Q +E++ + +RE ++ + + + ++ R
Sbjct: 323 EEKMREQEEKMWRQ--------------EERLWEQEKQMREQEQKMRDQEERMWEQDERL 368
Query: 179 RKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDD 238
R EKE +++ K ++++ E RE ++ R E R Q +Q + EE+ +
Sbjct: 369 R-EKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQ--KQEENMWEQ 425
Query: 239 RRRRYNSQFNPQLARRPRQQD 259
+ + Q P+ + +Q+
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQE 446
Score = 43.5 bits (101), Expect = 2e-04
Identities = 48/231 (20%), Positives = 97/231 (41%), Gaps = 31/231 (13%)
Query: 6 KKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQ-NSLPELE 64
KK+W D ++R +E E+K RE ++ +QE + + +K R Q + E E
Sbjct: 547 KKTW-----DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE 601
Query: 65 AAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEA 124
+ +E +E K + K +E+E+ + + QE+ + + + +
Sbjct: 602 ------------EKMQE--QEEKMWEQEEKMWEQEEEDKMQEQEE----MMWEQEEKMQE 643
Query: 125 QTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEG 184
Q + W Q R +EK++ + + +RE ++ + + + ++ + R ++E
Sbjct: 644 QEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEK 703
Query: 185 SEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDE 235
Q K +++ + RE ER R Q +QE PE +E
Sbjct: 704 MWGQEEKMWGQEEKMWGQEEMREKEER-------IRDQKEKMQERLPEHEE 747
Score = 42.0 bits (97), Expect = 5e-04
Identities = 45/218 (20%), Positives = 92/218 (42%), Gaps = 28/218 (12%)
Query: 19 RVRRDEAQARE-EEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVD 77
R+R E + RE EEK R + L +QE K+ R Q L E E + +
Sbjct: 263 RLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEE-QMQEQEEKMWE 321
Query: 78 LFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGR 137
++ E+ + + R + E+++Q +E+++K Q + W Q
Sbjct: 322 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKM------------RDQEERMWEQ----- 364
Query: 138 GGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLD 197
DE+++ + + +RE +K ++ + +E R R++K E++ +E
Sbjct: 365 ---------DERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKM 415
Query: 198 QLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDE 235
Q + E + + + + + L + + QE E++E
Sbjct: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 453
Score = 40.4 bits (93), Expect = 0.002
Identities = 56/260 (21%), Positives = 108/260 (41%), Gaps = 28/260 (10%)
Query: 6 KKSWHVRNK-DNVARVRRDEAQAREEEKE-RERRVLLAQQEARTEFLRKKARHQNSLPEL 63
+K W K R+R E + REEE+ RE+ + +QE +K Q LPE
Sbjct: 379 EKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 438
Query: 64 EAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEY--EEEK--RQEKERQEKALGILTYLGQ 119
+ + E + E + IR +E +E+K RQEK R+++ + +
Sbjct: 439 KEK---LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ---MWEQE 492
Query: 120 SAAEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSR 179
Q Q W Q DE+++ + + +RE +K ++ +
Sbjct: 493 EKMRDQEQKMWDQ-------EERMWEQDERLREKEERMREQKKMWQQEEK---------M 536
Query: 180 KEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDR 239
+E++ +++Q K +++R E RE ++ R E + R Q +QE + + E +++
Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK 596
Query: 240 RRRYNSQFNPQLARRPRQQD 259
+ Q + Q++
Sbjct: 597 MWEQEEKMQEQEEKMWEQEE 616
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 44.3 bits (103), Expect = 1e-04
Identities = 58/239 (24%), Positives = 96/239 (40%), Gaps = 45/239 (18%)
Query: 23 DEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFREL 82
DE + EEE+E E ++E +F ++ + E E E + F E
Sbjct: 887 DEEEEEEEEEEEEEE---EEEEEEEDFEEEEEDEEEYFEEEEEEE---------EEFEEE 934
Query: 83 LEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPPP 142
EE +G + +E E+E+ +E+ + + L T G+ A PP LPP PPP
Sbjct: 935 FEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGA---PPPPTLPPAL--PPP 989
Query: 143 GPAPDEKIKSRLDP--LREMQKHLGKKRQHGGDEG---------SRSRKEKEGSE----- 186
P + + +P L E+++ G + + G D S+ E+EG
Sbjct: 990 ESPPKVQPEPEPEPGLLLEVEEP-GTEEERGADTAPTLAPEALPSQGEVEREGESPAAGP 1048
Query: 187 ------KQRPKEPPSLDQLRAE---RLRREAAERSRAEALLARVQGRALQEGQPEEDET 236
++ P PP+L + E + E E + + ALQE E+D+T
Sbjct: 1049 PPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQE--KEQDDT 1105
Score = 29.6 bits (65), Expect = 2.8
Identities = 29/131 (22%), Positives = 48/131 (36%), Gaps = 17/131 (12%)
Query: 124 AQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLR-------------EMQKHLGKKRQH 170
A+ +P PG PPP P P L P + +++ L +
Sbjct: 825 AKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININ 884
Query: 171 GGDEGSRSRKEKEGSEKQRPKEPPSLDQL---RAERLRREAAERSRAEALLARVQGRALQ 227
DE +E+E E++ +E ++ E E E E +G L+
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE-LE 943
Query: 228 EGQPEEDETDD 238
E + EEDE ++
Sbjct: 944 EEEEEEDEEEE 954
Score = 29.3 bits (64), Expect = 3.7
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 4/51 (7%)
Query: 59 SLPELEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEK 109
+LP + G PG G LEE VI N EEE+ +E+E +E+
Sbjct: 854 TLPPPQLVPEGTPGGGGPPA----LEEDLTVININSSDEEEEEEEEEEEEE 900
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 43.9 bits (102), Expect = 1e-04
Identities = 55/225 (24%), Positives = 91/225 (40%), Gaps = 29/225 (12%)
Query: 22 RDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFRE 81
RD+ Q E EK++ L A QE K + L E + A G L R
Sbjct: 764 RDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARL-GQEQQTLNRA 822
Query: 82 LLEEGKG---VIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRG 138
L EEGK + RG E EE+KR ++ L +G+ + +A Q
Sbjct: 823 LEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQ----------- 871
Query: 139 GPPPGPAPDEKIKSRLDPLRE-MQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLD 197
++++L+ +E ++ + ++ D S + K G + + +
Sbjct: 872 -----------LQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQ 920
Query: 198 QLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRR 242
L+A + R+ A R E L R+QG QE + ++ DDR R+
Sbjct: 921 ALQASQAERDTA-RLDKELLAQRLQGLE-QEAENKKRSQDDRARQ 963
Score = 29.6 bits (65), Expect = 2.8
Identities = 54/224 (24%), Positives = 83/224 (37%), Gaps = 17/224 (7%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLF- 79
R+ EAQ +E + +R+L ++ R + QN L ++ E A DL
Sbjct: 413 RKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEP-AKEVLLKDLLE 471
Query: 80 -RELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSA------AEAQTQPPWYQ 132
RELLEE V+ G + EE+ R + G L S Q Q Q
Sbjct: 472 TRELLEE---VLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQ 528
Query: 133 LPPGRGGPPPGPAPDEKIKSRLDPL-REMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPK 191
L A E + ++ L R +Q+ L + + G S +K KE + +
Sbjct: 529 LRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQE 588
Query: 192 EPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDE 235
L QLR E+ E + E L ++ G + E
Sbjct: 589 ----LLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVE 628
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 43.9 bits (102), Expect = 1e-04
Identities = 65/242 (26%), Positives = 104/242 (42%), Gaps = 53/242 (21%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFR 80
R +E + E++ E R LA+ EA E Q L E A +L +
Sbjct: 1343 RMEEEERLAEQQRAEERERLAEVEAALE-------KQRQLAEAHAQAKAQAEREAKELQQ 1395
Query: 81 ELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGP 140
+ EE V+R + + ++Q++ QE+ L L QS+ EA+ Q Q
Sbjct: 1396 RMQEE---VVRREEAAVDAQQQKRSIQEE----LQQLRQSS-EAEIQAKARQAEAA---- 1443
Query: 141 PPGPAPDEKIKSRLDP-LREMQKHL-GKKRQHGGDEGS----RSRKEKEGSEKQRPKEPP 194
E+ + R++ +R ++ L +RQ GG EG R+R E+ ++K++ +E
Sbjct: 1444 -------ERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE-- 1494
Query: 195 SLDQLRAERLRR--------------EAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
AERLRR E A R +AEA AR + RALQ + + ++
Sbjct: 1495 -----EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1549
Query: 241 RR 242
RR
Sbjct: 1550 RR 1551
Score = 38.5 bits (88), Expect = 0.006
Identities = 63/259 (24%), Positives = 104/259 (40%), Gaps = 42/259 (16%)
Query: 19 RVRRDEAQAR--EEEKERERRVLLAQQEA-----------RTEFLRKKARHQNSLPELEA 65
R++ +EA+ R + E ER R+V +A + A R F K A+ + SL E
Sbjct: 1542 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1601
Query: 66 AEAGAPGSGPVDLFRELLEEGKGVIRGNKEYE---EEKRQEKERQEKALGILTYLGQSAA 122
A A +L EE + + E E EE +E ER + L A
Sbjct: 1602 AVA------------QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE 1649
Query: 123 EAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLR--EMQKHLGKKRQHGGDEGSRSRK 180
E Q Q A +K ++ + R + ++ ++R+ E + R+
Sbjct: 1650 EVAQQKSLAQ----------AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1699
Query: 181 EKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
EG+ +QR L +LRAE + E +R E LAR+Q A Q + E +
Sbjct: 1700 LAEGTAQQRLAAEQELIRLRAETEQGE-QQRQLLEEELARLQREAAAATQ-KRQELEAEL 1757
Query: 241 RRYNSQFNPQLARRPRQQD 259
+ ++ LA + R ++
Sbjct: 1758 AKVRAEMEVLLASKARAEE 1776
Score = 37.0 bits (84), Expect = 0.018
Identities = 53/247 (21%), Positives = 103/247 (41%), Gaps = 41/247 (16%)
Query: 23 DEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFREL 82
+E + R E +ER ++ L A++EA + RK A L E+E +A V+ R L
Sbjct: 1978 EEERRRREAEERVQKSLAAEEEAARQ--RKAA-----LEEVERLKA------KVEEARRL 2024
Query: 83 LEEGKGVIRGNKEYEEEKRQEK-ERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPP 141
E + + +E Q++ + +EKA + + Q L
Sbjct: 2025 RERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL-------- 2076
Query: 142 PGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEK-----QRPKEPPSL 196
++++ + R + + R E ++SR++ E +E+ + + +
Sbjct: 2077 ------DQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2130
Query: 197 DQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPR 256
Q AE+LR+EA + + A A+ + AL++ Q + E + ++ F Q R+
Sbjct: 2131 AQAAAEKLRKEAEQEA---ARRAQAEQAALRQKQAADAEMEKHKK-----FAEQTLRQKA 2182
Query: 257 QQDPHLT 263
Q + LT
Sbjct: 2183 QVEQELT 2189
Score = 36.2 bits (82), Expect = 0.030
Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 44/263 (16%)
Query: 12 RNKDNVARVRRDEAQAREEEKERERRVLLAQQE--ARTEFLRKKARHQNSLPELEAAEAG 69
R K VR+ E +E EK+R+ AQQ A E +R +A E E E
Sbjct: 1676 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA-------ETEQGEQQ 1728
Query: 70 APGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQ-EKALGILTYLGQSAAEAQTQP 128
R+LLEE ++ +KRQE E + K + L S A A+ +
Sbjct: 1729 ----------RQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEE- 1777
Query: 129 PWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQ 188
+ EK K RL+ + L ++ ++++++ +E+
Sbjct: 1778 --------------SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1823
Query: 189 RPKEPPSLDQLRAERLRR-EAAERSRAEALLARVQGRALQE--GQPEEDETDDRRR---- 241
++ +++ AE+L A R + EA +A + A E + EDE RRR
Sbjct: 1824 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1883
Query: 242 --RYNSQFNPQLARRPRQQDPHL 262
++ + +LA+ + D L
Sbjct: 1884 AAQHKADIEERLAQLRKASDSEL 1906
Score = 34.7 bits (78), Expect = 0.088
Identities = 59/264 (22%), Positives = 106/264 (40%), Gaps = 35/264 (13%)
Query: 11 VRNKDNVARVRRDEAQAREEEKERERRVLLAQQEAR--TEFLRKKARHQNSLPE--LEAA 66
+R+KDN R ++EA+ ++ E R+ +A QEA + + Q +L E L+
Sbjct: 2256 LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2315
Query: 67 EAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQT 126
+ + ELL++ K + +E +++KE+ + L T Q EA+
Sbjct: 2316 MQAVQEATRLKAEAELLQQQKELA---QEQARRLQEDKEQMAQQLAEETQGFQRTLEAER 2372
Query: 127 QPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSE 186
Q QL A E++K R+ + Q + Q + ++ +E
Sbjct: 2373 Q---RQLEMS--------AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2421
Query: 187 KQRPKEPPSLDQLR---------AERLRREAAERSR------AEALLARVQGRALQEGQP 231
++ + L AERLR AE R EA L +++ +Q Q
Sbjct: 2422 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2481
Query: 232 EE--DETDDRRRRYNSQFNPQLAR 253
E+ ET ++ + S+ + L R
Sbjct: 2482 EQLLQETQALQQSFLSEKDSLLQR 2505
Score = 29.6 bits (65), Expect = 2.8
Identities = 54/255 (21%), Positives = 100/255 (39%), Gaps = 45/255 (17%)
Query: 14 KDNVARVRRDEAQAREEEKERER-RVLLAQQEARTEFLRKKARH-QNSLPELEAAEAGAP 71
++ V V+ E Q ++ + + ER R +A+ E E L+++A+ Q E++ +
Sbjct: 2425 QEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL 2484
Query: 72 GSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWY 131
L + L E +++ + E+EK + ++ + + L + Q Q
Sbjct: 2485 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM--- 2541
Query: 132 QLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEK--------- 182
E+ + RL + M++ ++RQH +EG R ++E+
Sbjct: 2542 ----------------EQERQRL--VASMEE--ARRRQHEAEEGVRRKQEELQQLEQQRR 2581
Query: 183 -----EGSEKQRPKEPPSL--DQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDE 235
E QR +E L +Q RA E S+ A GR +G E E
Sbjct: 2582 QQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAE 2641
Query: 236 T----DDRRRRYNSQ 246
D RR+ ++Q
Sbjct: 2642 PEHSFDGLRRKVSAQ 2656
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 43.9 bits (102), Expect = 1e-04
Identities = 65/242 (26%), Positives = 104/242 (42%), Gaps = 53/242 (21%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFR 80
R +E + E++ E R LA+ EA E Q L E A +L +
Sbjct: 1347 RMEEEERLAEQQRAEERERLAEVEAALE-------KQRQLAEAHAQAKAQAEREAKELQQ 1399
Query: 81 ELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGP 140
+ EE V+R + + ++Q++ QE+ L L QS+ EA+ Q Q
Sbjct: 1400 RMQEE---VVRREEAAVDAQQQKRSIQEE----LQQLRQSS-EAEIQAKARQAEAA---- 1447
Query: 141 PPGPAPDEKIKSRLDP-LREMQKHL-GKKRQHGGDEGS----RSRKEKEGSEKQRPKEPP 194
E+ + R++ +R ++ L +RQ GG EG R+R E+ ++K++ +E
Sbjct: 1448 -------ERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE-- 1498
Query: 195 SLDQLRAERLRR--------------EAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
AERLRR E A R +AEA AR + RALQ + + ++
Sbjct: 1499 -----EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1553
Query: 241 RR 242
RR
Sbjct: 1554 RR 1555
Score = 38.5 bits (88), Expect = 0.006
Identities = 63/259 (24%), Positives = 104/259 (40%), Gaps = 42/259 (16%)
Query: 19 RVRRDEAQAR--EEEKERERRVLLAQQEA-----------RTEFLRKKARHQNSLPELEA 65
R++ +EA+ R + E ER R+V +A + A R F K A+ + SL E
Sbjct: 1546 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1605
Query: 66 AEAGAPGSGPVDLFRELLEEGKGVIRGNKEYE---EEKRQEKERQEKALGILTYLGQSAA 122
A A +L EE + + E E EE +E ER + L A
Sbjct: 1606 AVA------------QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE 1653
Query: 123 EAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLR--EMQKHLGKKRQHGGDEGSRSRK 180
E Q Q A +K ++ + R + ++ ++R+ E + R+
Sbjct: 1654 EVAQQKSLAQ----------AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1703
Query: 181 EKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
EG+ +QR L +LRAE + E +R E LAR+Q A Q + E +
Sbjct: 1704 LAEGTAQQRLAAEQELIRLRAETEQGE-QQRQLLEEELARLQREAAAATQ-KRQELEAEL 1761
Query: 241 RRYNSQFNPQLARRPRQQD 259
+ ++ LA + R ++
Sbjct: 1762 AKVRAEMEVLLASKARAEE 1780
Score = 37.0 bits (84), Expect = 0.018
Identities = 53/247 (21%), Positives = 103/247 (41%), Gaps = 41/247 (16%)
Query: 23 DEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFREL 82
+E + R E +ER ++ L A++EA + RK A L E+E +A V+ R L
Sbjct: 1982 EEERRRREAEERVQKSLAAEEEAARQ--RKAA-----LEEVERLKA------KVEEARRL 2028
Query: 83 LEEGKGVIRGNKEYEEEKRQEK-ERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPP 141
E + + +E Q++ + +EKA + + Q L
Sbjct: 2029 RERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL-------- 2080
Query: 142 PGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEK-----QRPKEPPSL 196
++++ + R + + R E ++SR++ E +E+ + + +
Sbjct: 2081 ------DQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2134
Query: 197 DQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPR 256
Q AE+LR+EA + + A A+ + AL++ Q + E + ++ F Q R+
Sbjct: 2135 AQAAAEKLRKEAEQEA---ARRAQAEQAALRQKQAADAEMEKHKK-----FAEQTLRQKA 2186
Query: 257 QQDPHLT 263
Q + LT
Sbjct: 2187 QVEQELT 2193
Score = 36.2 bits (82), Expect = 0.030
Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 44/263 (16%)
Query: 12 RNKDNVARVRRDEAQAREEEKERERRVLLAQQE--ARTEFLRKKARHQNSLPELEAAEAG 69
R K VR+ E +E EK+R+ AQQ A E +R +A E E E
Sbjct: 1680 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA-------ETEQGEQQ 1732
Query: 70 APGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQ-EKALGILTYLGQSAAEAQTQP 128
R+LLEE ++ +KRQE E + K + L S A A+ +
Sbjct: 1733 ----------RQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEE- 1781
Query: 129 PWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQ 188
+ EK K RL+ + L ++ ++++++ +E+
Sbjct: 1782 --------------SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1827
Query: 189 RPKEPPSLDQLRAERLRR-EAAERSRAEALLARVQGRALQE--GQPEEDETDDRRR---- 241
++ +++ AE+L A R + EA +A + A E + EDE RRR
Sbjct: 1828 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1887
Query: 242 --RYNSQFNPQLARRPRQQDPHL 262
++ + +LA+ + D L
Sbjct: 1888 AAQHKADIEERLAQLRKASDSEL 1910
Score = 34.7 bits (78), Expect = 0.088
Identities = 59/264 (22%), Positives = 106/264 (40%), Gaps = 35/264 (13%)
Query: 11 VRNKDNVARVRRDEAQAREEEKERERRVLLAQQEAR--TEFLRKKARHQNSLPE--LEAA 66
+R+KDN R ++EA+ ++ E R+ +A QEA + + Q +L E L+
Sbjct: 2260 LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2319
Query: 67 EAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQT 126
+ + ELL++ K + +E +++KE+ + L T Q EA+
Sbjct: 2320 MQAVQEATRLKAEAELLQQQKELA---QEQARRLQEDKEQMAQQLAEETQGFQRTLEAER 2376
Query: 127 QPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSE 186
Q QL A E++K R+ + Q + Q + ++ +E
Sbjct: 2377 Q---RQLEMS--------AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2425
Query: 187 KQRPKEPPSLDQLR---------AERLRREAAERSR------AEALLARVQGRALQEGQP 231
++ + L AERLR AE R EA L +++ +Q Q
Sbjct: 2426 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2485
Query: 232 EE--DETDDRRRRYNSQFNPQLAR 253
E+ ET ++ + S+ + L R
Sbjct: 2486 EQLLQETQALQQSFLSEKDSLLQR 2509
Score = 29.6 bits (65), Expect = 2.8
Identities = 54/255 (21%), Positives = 100/255 (39%), Gaps = 45/255 (17%)
Query: 14 KDNVARVRRDEAQAREEEKERER-RVLLAQQEARTEFLRKKARH-QNSLPELEAAEAGAP 71
++ V V+ E Q ++ + + ER R +A+ E E L+++A+ Q E++ +
Sbjct: 2429 QEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL 2488
Query: 72 GSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWY 131
L + L E +++ + E+EK + ++ + + L + Q Q
Sbjct: 2489 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM--- 2545
Query: 132 QLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEK--------- 182
E+ + RL + M++ ++RQH +EG R ++E+
Sbjct: 2546 ----------------EQERQRL--VASMEE--ARRRQHEAEEGVRRKQEELQQLEQQRR 2585
Query: 183 -----EGSEKQRPKEPPSL--DQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDE 235
E QR +E L +Q RA E S+ A GR +G E E
Sbjct: 2586 QQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAE 2645
Query: 236 T----DDRRRRYNSQ 246
D RR+ ++Q
Sbjct: 2646 PEHSFDGLRRKVSAQ 2660
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 43.9 bits (102), Expect = 1e-04
Identities = 65/242 (26%), Positives = 104/242 (42%), Gaps = 53/242 (21%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFR 80
R +E + E++ E R LA+ EA E Q L E A +L +
Sbjct: 1343 RMEEEERLAEQQRAEERERLAEVEAALE-------KQRQLAEAHAQAKAQAEREAKELQQ 1395
Query: 81 ELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGP 140
+ EE V+R + + ++Q++ QE+ L L QS+ EA+ Q Q
Sbjct: 1396 RMQEE---VVRREEAAVDAQQQKRSIQEE----LQQLRQSS-EAEIQAKARQAEAA---- 1443
Query: 141 PPGPAPDEKIKSRLDP-LREMQKHL-GKKRQHGGDEGS----RSRKEKEGSEKQRPKEPP 194
E+ + R++ +R ++ L +RQ GG EG R+R E+ ++K++ +E
Sbjct: 1444 -------ERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE-- 1494
Query: 195 SLDQLRAERLRR--------------EAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
AERLRR E A R +AEA AR + RALQ + + ++
Sbjct: 1495 -----EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1549
Query: 241 RR 242
RR
Sbjct: 1550 RR 1551
Score = 38.5 bits (88), Expect = 0.006
Identities = 63/259 (24%), Positives = 104/259 (40%), Gaps = 42/259 (16%)
Query: 19 RVRRDEAQAR--EEEKERERRVLLAQQEA-----------RTEFLRKKARHQNSLPELEA 65
R++ +EA+ R + E ER R+V +A + A R F K A+ + SL E
Sbjct: 1542 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1601
Query: 66 AEAGAPGSGPVDLFRELLEEGKGVIRGNKEYE---EEKRQEKERQEKALGILTYLGQSAA 122
A A +L EE + + E E EE +E ER + L A
Sbjct: 1602 AVA------------QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE 1649
Query: 123 EAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLR--EMQKHLGKKRQHGGDEGSRSRK 180
E Q Q A +K ++ + R + ++ ++R+ E + R+
Sbjct: 1650 EVAQQKSLAQ----------AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1699
Query: 181 EKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
EG+ +QR L +LRAE + E +R E LAR+Q A Q + E +
Sbjct: 1700 LAEGTAQQRLAAEQELIRLRAETEQGE-QQRQLLEEELARLQREAAAATQ-KRQELEAEL 1757
Query: 241 RRYNSQFNPQLARRPRQQD 259
+ ++ LA + R ++
Sbjct: 1758 AKVRAEMEVLLASKARAEE 1776
Score = 37.0 bits (84), Expect = 0.018
Identities = 53/247 (21%), Positives = 103/247 (41%), Gaps = 41/247 (16%)
Query: 23 DEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFREL 82
+E + R E +ER ++ L A++EA + RK A L E+E +A V+ R L
Sbjct: 1978 EEERRRREAEERVQKSLAAEEEAARQ--RKAA-----LEEVERLKA------KVEEARRL 2024
Query: 83 LEEGKGVIRGNKEYEEEKRQEK-ERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPP 141
E + + +E Q++ + +EKA + + Q L
Sbjct: 2025 RERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL-------- 2076
Query: 142 PGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEK-----QRPKEPPSL 196
++++ + R + + R E ++SR++ E +E+ + + +
Sbjct: 2077 ------DQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2130
Query: 197 DQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPR 256
Q AE+LR+EA + + A A+ + AL++ Q + E + ++ F Q R+
Sbjct: 2131 AQAAAEKLRKEAEQEA---ARRAQAEQAALRQKQAADAEMEKHKK-----FAEQTLRQKA 2182
Query: 257 QQDPHLT 263
Q + LT
Sbjct: 2183 QVEQELT 2189
Score = 36.2 bits (82), Expect = 0.030
Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 44/263 (16%)
Query: 12 RNKDNVARVRRDEAQAREEEKERERRVLLAQQE--ARTEFLRKKARHQNSLPELEAAEAG 69
R K VR+ E +E EK+R+ AQQ A E +R +A E E E
Sbjct: 1676 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA-------ETEQGEQQ 1728
Query: 70 APGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQ-EKALGILTYLGQSAAEAQTQP 128
R+LLEE ++ +KRQE E + K + L S A A+ +
Sbjct: 1729 ----------RQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEE- 1777
Query: 129 PWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQ 188
+ EK K RL+ + L ++ ++++++ +E+
Sbjct: 1778 --------------SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1823
Query: 189 RPKEPPSLDQLRAERLRR-EAAERSRAEALLARVQGRALQE--GQPEEDETDDRRR---- 241
++ +++ AE+L A R + EA +A + A E + EDE RRR
Sbjct: 1824 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1883
Query: 242 --RYNSQFNPQLARRPRQQDPHL 262
++ + +LA+ + D L
Sbjct: 1884 AAQHKADIEERLAQLRKASDSEL 1906
Score = 34.7 bits (78), Expect = 0.088
Identities = 59/264 (22%), Positives = 106/264 (40%), Gaps = 35/264 (13%)
Query: 11 VRNKDNVARVRRDEAQAREEEKERERRVLLAQQEAR--TEFLRKKARHQNSLPE--LEAA 66
+R+KDN R ++EA+ ++ E R+ +A QEA + + Q +L E L+
Sbjct: 2256 LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2315
Query: 67 EAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQT 126
+ + ELL++ K + +E +++KE+ + L T Q EA+
Sbjct: 2316 MQAVQEATRLKAEAELLQQQKELA---QEQARRLQEDKEQMAQQLAEETQGFQRTLEAER 2372
Query: 127 QPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSE 186
Q QL A E++K R+ + Q + Q + ++ +E
Sbjct: 2373 Q---RQLEMS--------AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2421
Query: 187 KQRPKEPPSLDQLR---------AERLRREAAERSR------AEALLARVQGRALQEGQP 231
++ + L AERLR AE R EA L +++ +Q Q
Sbjct: 2422 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2481
Query: 232 EE--DETDDRRRRYNSQFNPQLAR 253
E+ ET ++ + S+ + L R
Sbjct: 2482 EQLLQETQALQQSFLSEKDSLLQR 2505
Score = 29.6 bits (65), Expect = 2.8
Identities = 54/255 (21%), Positives = 100/255 (39%), Gaps = 45/255 (17%)
Query: 14 KDNVARVRRDEAQAREEEKERER-RVLLAQQEARTEFLRKKARH-QNSLPELEAAEAGAP 71
++ V V+ E Q ++ + + ER R +A+ E E L+++A+ Q E++ +
Sbjct: 2425 QEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL 2484
Query: 72 GSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWY 131
L + L E +++ + E+EK + ++ + + L + Q Q
Sbjct: 2485 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM--- 2541
Query: 132 QLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEK--------- 182
E+ + RL + M++ ++RQH +EG R ++E+
Sbjct: 2542 ----------------EQERQRL--VASMEE--ARRRQHEAEEGVRRKQEELQQLEQQRR 2581
Query: 183 -----EGSEKQRPKEPPSL--DQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDE 235
E QR +E L +Q RA E S+ A GR +G E E
Sbjct: 2582 QQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAE 2641
Query: 236 T----DDRRRRYNSQ 246
D RR+ ++Q
Sbjct: 2642 PEHSFDGLRRKVSAQ 2656
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 43.9 bits (102), Expect = 1e-04
Identities = 65/242 (26%), Positives = 104/242 (42%), Gaps = 53/242 (21%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFR 80
R +E + E++ E R LA+ EA E Q L E A +L +
Sbjct: 1311 RMEEEERLAEQQRAEERERLAEVEAALE-------KQRQLAEAHAQAKAQAEREAKELQQ 1363
Query: 81 ELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGP 140
+ EE V+R + + ++Q++ QE+ L L QS+ EA+ Q Q
Sbjct: 1364 RMQEE---VVRREEAAVDAQQQKRSIQEE----LQQLRQSS-EAEIQAKARQAEAA---- 1411
Query: 141 PPGPAPDEKIKSRLDP-LREMQKHL-GKKRQHGGDEGS----RSRKEKEGSEKQRPKEPP 194
E+ + R++ +R ++ L +RQ GG EG R+R E+ ++K++ +E
Sbjct: 1412 -------ERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE-- 1462
Query: 195 SLDQLRAERLRR--------------EAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
AERLRR E A R +AEA AR + RALQ + + ++
Sbjct: 1463 -----EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1517
Query: 241 RR 242
RR
Sbjct: 1518 RR 1519
Score = 38.5 bits (88), Expect = 0.006
Identities = 63/259 (24%), Positives = 104/259 (40%), Gaps = 42/259 (16%)
Query: 19 RVRRDEAQAR--EEEKERERRVLLAQQEA-----------RTEFLRKKARHQNSLPELEA 65
R++ +EA+ R + E ER R+V +A + A R F K A+ + SL E
Sbjct: 1510 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1569
Query: 66 AEAGAPGSGPVDLFRELLEEGKGVIRGNKEYE---EEKRQEKERQEKALGILTYLGQSAA 122
A A +L EE + + E E EE +E ER + L A
Sbjct: 1570 AVA------------QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE 1617
Query: 123 EAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLR--EMQKHLGKKRQHGGDEGSRSRK 180
E Q Q A +K ++ + R + ++ ++R+ E + R+
Sbjct: 1618 EVAQQKSLAQ----------AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1667
Query: 181 EKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
EG+ +QR L +LRAE + E +R E LAR+Q A Q + E +
Sbjct: 1668 LAEGTAQQRLAAEQELIRLRAETEQGE-QQRQLLEEELARLQREAAAATQ-KRQELEAEL 1725
Query: 241 RRYNSQFNPQLARRPRQQD 259
+ ++ LA + R ++
Sbjct: 1726 AKVRAEMEVLLASKARAEE 1744
Score = 37.0 bits (84), Expect = 0.018
Identities = 53/247 (21%), Positives = 103/247 (41%), Gaps = 41/247 (16%)
Query: 23 DEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFREL 82
+E + R E +ER ++ L A++EA + RK A L E+E +A V+ R L
Sbjct: 1946 EEERRRREAEERVQKSLAAEEEAARQ--RKAA-----LEEVERLKA------KVEEARRL 1992
Query: 83 LEEGKGVIRGNKEYEEEKRQEK-ERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPP 141
E + + +E Q++ + +EKA + + Q L
Sbjct: 1993 RERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL-------- 2044
Query: 142 PGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEK-----QRPKEPPSL 196
++++ + R + + R E ++SR++ E +E+ + + +
Sbjct: 2045 ------DQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2098
Query: 197 DQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPR 256
Q AE+LR+EA + + A A+ + AL++ Q + E + ++ F Q R+
Sbjct: 2099 AQAAAEKLRKEAEQEA---ARRAQAEQAALRQKQAADAEMEKHKK-----FAEQTLRQKA 2150
Query: 257 QQDPHLT 263
Q + LT
Sbjct: 2151 QVEQELT 2157
Score = 36.2 bits (82), Expect = 0.030
Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 44/263 (16%)
Query: 12 RNKDNVARVRRDEAQAREEEKERERRVLLAQQE--ARTEFLRKKARHQNSLPELEAAEAG 69
R K VR+ E +E EK+R+ AQQ A E +R +A E E E
Sbjct: 1644 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA-------ETEQGEQQ 1696
Query: 70 APGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQ-EKALGILTYLGQSAAEAQTQP 128
R+LLEE ++ +KRQE E + K + L S A A+ +
Sbjct: 1697 ----------RQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEE- 1745
Query: 129 PWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQ 188
+ EK K RL+ + L ++ ++++++ +E+
Sbjct: 1746 --------------SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1791
Query: 189 RPKEPPSLDQLRAERLRR-EAAERSRAEALLARVQGRALQE--GQPEEDETDDRRR---- 241
++ +++ AE+L A R + EA +A + A E + EDE RRR
Sbjct: 1792 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1851
Query: 242 --RYNSQFNPQLARRPRQQDPHL 262
++ + +LA+ + D L
Sbjct: 1852 AAQHKADIEERLAQLRKASDSEL 1874
Score = 34.7 bits (78), Expect = 0.088
Identities = 59/264 (22%), Positives = 106/264 (40%), Gaps = 35/264 (13%)
Query: 11 VRNKDNVARVRRDEAQAREEEKERERRVLLAQQEAR--TEFLRKKARHQNSLPE--LEAA 66
+R+KDN R ++EA+ ++ E R+ +A QEA + + Q +L E L+
Sbjct: 2224 LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2283
Query: 67 EAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQT 126
+ + ELL++ K + +E +++KE+ + L T Q EA+
Sbjct: 2284 MQAVQEATRLKAEAELLQQQKELA---QEQARRLQEDKEQMAQQLAEETQGFQRTLEAER 2340
Query: 127 QPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSE 186
Q QL A E++K R+ + Q + Q + ++ +E
Sbjct: 2341 Q---RQLEMS--------AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2389
Query: 187 KQRPKEPPSLDQLR---------AERLRREAAERSR------AEALLARVQGRALQEGQP 231
++ + L AERLR AE R EA L +++ +Q Q
Sbjct: 2390 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2449
Query: 232 EE--DETDDRRRRYNSQFNPQLAR 253
E+ ET ++ + S+ + L R
Sbjct: 2450 EQLLQETQALQQSFLSEKDSLLQR 2473
Score = 29.6 bits (65), Expect = 2.8
Identities = 54/255 (21%), Positives = 100/255 (39%), Gaps = 45/255 (17%)
Query: 14 KDNVARVRRDEAQAREEEKERER-RVLLAQQEARTEFLRKKARH-QNSLPELEAAEAGAP 71
++ V V+ E Q ++ + + ER R +A+ E E L+++A+ Q E++ +
Sbjct: 2393 QEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL 2452
Query: 72 GSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWY 131
L + L E +++ + E+EK + ++ + + L + Q Q
Sbjct: 2453 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM--- 2509
Query: 132 QLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEK--------- 182
E+ + RL + M++ ++RQH +EG R ++E+
Sbjct: 2510 ----------------EQERQRL--VASMEE--ARRRQHEAEEGVRRKQEELQQLEQQRR 2549
Query: 183 -----EGSEKQRPKEPPSL--DQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDE 235
E QR +E L +Q RA E S+ A GR +G E E
Sbjct: 2550 QQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAE 2609
Query: 236 T----DDRRRRYNSQ 246
D RR+ ++Q
Sbjct: 2610 PEHSFDGLRRKVSAQ 2624
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 43.9 bits (102), Expect = 1e-04
Identities = 65/242 (26%), Positives = 104/242 (42%), Gaps = 53/242 (21%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFR 80
R +E + E++ E R LA+ EA E Q L E A +L +
Sbjct: 1480 RMEEEERLAEQQRAEERERLAEVEAALE-------KQRQLAEAHAQAKAQAEREAKELQQ 1532
Query: 81 ELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGP 140
+ EE V+R + + ++Q++ QE+ L L QS+ EA+ Q Q
Sbjct: 1533 RMQEE---VVRREEAAVDAQQQKRSIQEE----LQQLRQSS-EAEIQAKARQAEAA---- 1580
Query: 141 PPGPAPDEKIKSRLDP-LREMQKHL-GKKRQHGGDEGS----RSRKEKEGSEKQRPKEPP 194
E+ + R++ +R ++ L +RQ GG EG R+R E+ ++K++ +E
Sbjct: 1581 -------ERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE-- 1631
Query: 195 SLDQLRAERLRR--------------EAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
AERLRR E A R +AEA AR + RALQ + + ++
Sbjct: 1632 -----EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1686
Query: 241 RR 242
RR
Sbjct: 1687 RR 1688
Score = 38.5 bits (88), Expect = 0.006
Identities = 63/259 (24%), Positives = 104/259 (40%), Gaps = 42/259 (16%)
Query: 19 RVRRDEAQAR--EEEKERERRVLLAQQEA-----------RTEFLRKKARHQNSLPELEA 65
R++ +EA+ R + E ER R+V +A + A R F K A+ + SL E
Sbjct: 1679 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1738
Query: 66 AEAGAPGSGPVDLFRELLEEGKGVIRGNKEYE---EEKRQEKERQEKALGILTYLGQSAA 122
A A +L EE + + E E EE +E ER + L A
Sbjct: 1739 AVA------------QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE 1786
Query: 123 EAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLR--EMQKHLGKKRQHGGDEGSRSRK 180
E Q Q A +K ++ + R + ++ ++R+ E + R+
Sbjct: 1787 EVAQQKSLAQ----------AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1836
Query: 181 EKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
EG+ +QR L +LRAE + E +R E LAR+Q A Q + E +
Sbjct: 1837 LAEGTAQQRLAAEQELIRLRAETEQGE-QQRQLLEEELARLQREAAAATQ-KRQELEAEL 1894
Query: 241 RRYNSQFNPQLARRPRQQD 259
+ ++ LA + R ++
Sbjct: 1895 AKVRAEMEVLLASKARAEE 1913
Score = 37.0 bits (84), Expect = 0.018
Identities = 53/247 (21%), Positives = 103/247 (41%), Gaps = 41/247 (16%)
Query: 23 DEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFREL 82
+E + R E +ER ++ L A++EA + RK A L E+E +A V+ R L
Sbjct: 2115 EEERRRREAEERVQKSLAAEEEAARQ--RKAA-----LEEVERLKA------KVEEARRL 2161
Query: 83 LEEGKGVIRGNKEYEEEKRQEK-ERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPP 141
E + + +E Q++ + +EKA + + Q L
Sbjct: 2162 RERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL-------- 2213
Query: 142 PGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEK-----QRPKEPPSL 196
++++ + R + + R E ++SR++ E +E+ + + +
Sbjct: 2214 ------DQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2267
Query: 197 DQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPR 256
Q AE+LR+EA + + A A+ + AL++ Q + E + ++ F Q R+
Sbjct: 2268 AQAAAEKLRKEAEQEA---ARRAQAEQAALRQKQAADAEMEKHKK-----FAEQTLRQKA 2319
Query: 257 QQDPHLT 263
Q + LT
Sbjct: 2320 QVEQELT 2326
Score = 36.2 bits (82), Expect = 0.030
Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 44/263 (16%)
Query: 12 RNKDNVARVRRDEAQAREEEKERERRVLLAQQE--ARTEFLRKKARHQNSLPELEAAEAG 69
R K VR+ E +E EK+R+ AQQ A E +R +A E E E
Sbjct: 1813 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA-------ETEQGEQQ 1865
Query: 70 APGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQ-EKALGILTYLGQSAAEAQTQP 128
R+LLEE ++ +KRQE E + K + L S A A+ +
Sbjct: 1866 ----------RQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEE- 1914
Query: 129 PWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQ 188
+ EK K RL+ + L ++ ++++++ +E+
Sbjct: 1915 --------------SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1960
Query: 189 RPKEPPSLDQLRAERLRR-EAAERSRAEALLARVQGRALQE--GQPEEDETDDRRR---- 241
++ +++ AE+L A R + EA +A + A E + EDE RRR
Sbjct: 1961 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 2020
Query: 242 --RYNSQFNPQLARRPRQQDPHL 262
++ + +LA+ + D L
Sbjct: 2021 AAQHKADIEERLAQLRKASDSEL 2043
Score = 34.7 bits (78), Expect = 0.088
Identities = 59/264 (22%), Positives = 106/264 (40%), Gaps = 35/264 (13%)
Query: 11 VRNKDNVARVRRDEAQAREEEKERERRVLLAQQEAR--TEFLRKKARHQNSLPE--LEAA 66
+R+KDN R ++EA+ ++ E R+ +A QEA + + Q +L E L+
Sbjct: 2393 LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2452
Query: 67 EAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQT 126
+ + ELL++ K + +E +++KE+ + L T Q EA+
Sbjct: 2453 MQAVQEATRLKAEAELLQQQKELA---QEQARRLQEDKEQMAQQLAEETQGFQRTLEAER 2509
Query: 127 QPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSE 186
Q QL A E++K R+ + Q + Q + ++ +E
Sbjct: 2510 Q---RQLEMS--------AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2558
Query: 187 KQRPKEPPSLDQLR---------AERLRREAAERSR------AEALLARVQGRALQEGQP 231
++ + L AERLR AE R EA L +++ +Q Q
Sbjct: 2559 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2618
Query: 232 EE--DETDDRRRRYNSQFNPQLAR 253
E+ ET ++ + S+ + L R
Sbjct: 2619 EQLLQETQALQQSFLSEKDSLLQR 2642
Score = 29.6 bits (65), Expect = 2.8
Identities = 54/255 (21%), Positives = 100/255 (39%), Gaps = 45/255 (17%)
Query: 14 KDNVARVRRDEAQAREEEKERER-RVLLAQQEARTEFLRKKARH-QNSLPELEAAEAGAP 71
++ V V+ E Q ++ + + ER R +A+ E E L+++A+ Q E++ +
Sbjct: 2562 QEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL 2621
Query: 72 GSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWY 131
L + L E +++ + E+EK + ++ + + L + Q Q
Sbjct: 2622 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM--- 2678
Query: 132 QLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEK--------- 182
E+ + RL + M++ ++RQH +EG R ++E+
Sbjct: 2679 ----------------EQERQRL--VASMEE--ARRRQHEAEEGVRRKQEELQQLEQQRR 2718
Query: 183 -----EGSEKQRPKEPPSL--DQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDE 235
E QR +E L +Q RA E S+ A GR +G E E
Sbjct: 2719 QQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAE 2778
Query: 236 T----DDRRRRYNSQ 246
D RR+ ++Q
Sbjct: 2779 PEHSFDGLRRKVSAQ 2793
Score = 28.5 bits (62), Expect = 6.3
Identities = 18/58 (31%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 117 LGQSAAEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLRE-MQKHLGKKRQHGGD 173
L + + E P Q R GP P PA DE+ + + + + KHL K ++H D
Sbjct: 145 LEEVSPETPVVPATTQRTLARPGPEPAPATDERDRVQKKTFTKWVNKHLIKAQRHISD 202
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 43.9 bits (102), Expect = 1e-04
Identities = 65/242 (26%), Positives = 104/242 (42%), Gaps = 53/242 (21%)
Query: 21 RRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFR 80
R +E + E++ E R LA+ EA E Q L E A +L +
Sbjct: 1321 RMEEEERLAEQQRAEERERLAEVEAALE-------KQRQLAEAHAQAKAQAEREAKELQQ 1373
Query: 81 ELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGP 140
+ EE V+R + + ++Q++ QE+ L L QS+ EA+ Q Q
Sbjct: 1374 RMQEE---VVRREEAAVDAQQQKRSIQEE----LQQLRQSS-EAEIQAKARQAEAA---- 1421
Query: 141 PPGPAPDEKIKSRLDP-LREMQKHL-GKKRQHGGDEGS----RSRKEKEGSEKQRPKEPP 194
E+ + R++ +R ++ L +RQ GG EG R+R E+ ++K++ +E
Sbjct: 1422 -------ERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE-- 1472
Query: 195 SLDQLRAERLRR--------------EAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
AERLRR E A R +AEA AR + RALQ + + ++
Sbjct: 1473 -----EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1527
Query: 241 RR 242
RR
Sbjct: 1528 RR 1529
Score = 38.5 bits (88), Expect = 0.006
Identities = 63/259 (24%), Positives = 104/259 (40%), Gaps = 42/259 (16%)
Query: 19 RVRRDEAQAR--EEEKERERRVLLAQQEA-----------RTEFLRKKARHQNSLPELEA 65
R++ +EA+ R + E ER R+V +A + A R F K A+ + SL E
Sbjct: 1520 RLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHV 1579
Query: 66 AEAGAPGSGPVDLFRELLEEGKGVIRGNKEYE---EEKRQEKERQEKALGILTYLGQSAA 122
A A +L EE + + E E EE +E ER + L A
Sbjct: 1580 AVA------------QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE 1627
Query: 123 EAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLR--EMQKHLGKKRQHGGDEGSRSRK 180
E Q Q A +K ++ + R + ++ ++R+ E + R+
Sbjct: 1628 EVAQQKSLAQ----------AEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1677
Query: 181 EKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRR 240
EG+ +QR L +LRAE + E +R E LAR+Q A Q + E +
Sbjct: 1678 LAEGTAQQRLAAEQELIRLRAETEQGE-QQRQLLEEELARLQREAAAATQ-KRQELEAEL 1735
Query: 241 RRYNSQFNPQLARRPRQQD 259
+ ++ LA + R ++
Sbjct: 1736 AKVRAEMEVLLASKARAEE 1754
Score = 37.0 bits (84), Expect = 0.018
Identities = 53/247 (21%), Positives = 103/247 (41%), Gaps = 41/247 (16%)
Query: 23 DEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFREL 82
+E + R E +ER ++ L A++EA + RK A L E+E +A V+ R L
Sbjct: 1956 EEERRRREAEERVQKSLAAEEEAARQ--RKAA-----LEEVERLKA------KVEEARRL 2002
Query: 83 LEEGKGVIRGNKEYEEEKRQEK-ERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPP 141
E + + +E Q++ + +EKA + + Q L
Sbjct: 2003 RERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVL-------- 2054
Query: 142 PGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEK-----QRPKEPPSL 196
++++ + R + + R E ++SR++ E +E+ + + +
Sbjct: 2055 ------DQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2108
Query: 197 DQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPR 256
Q AE+LR+EA + + A A+ + AL++ Q + E + ++ F Q R+
Sbjct: 2109 AQAAAEKLRKEAEQEA---ARRAQAEQAALRQKQAADAEMEKHKK-----FAEQTLRQKA 2160
Query: 257 QQDPHLT 263
Q + LT
Sbjct: 2161 QVEQELT 2167
Score = 36.2 bits (82), Expect = 0.030
Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 44/263 (16%)
Query: 12 RNKDNVARVRRDEAQAREEEKERERRVLLAQQE--ARTEFLRKKARHQNSLPELEAAEAG 69
R K VR+ E +E EK+R+ AQQ A E +R +A E E E
Sbjct: 1654 RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRA-------ETEQGEQQ 1706
Query: 70 APGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQ-EKALGILTYLGQSAAEAQTQP 128
R+LLEE ++ +KRQE E + K + L S A A+ +
Sbjct: 1707 ----------RQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEE- 1755
Query: 129 PWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQ 188
+ EK K RL+ + L ++ ++++++ +E+
Sbjct: 1756 --------------SRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1801
Query: 189 RPKEPPSLDQLRAERLRR-EAAERSRAEALLARVQGRALQE--GQPEEDETDDRRR---- 241
++ +++ AE+L A R + EA +A + A E + EDE RRR
Sbjct: 1802 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1861
Query: 242 --RYNSQFNPQLARRPRQQDPHL 262
++ + +LA+ + D L
Sbjct: 1862 AAQHKADIEERLAQLRKASDSEL 1884
Score = 34.7 bits (78), Expect = 0.088
Identities = 59/264 (22%), Positives = 106/264 (40%), Gaps = 35/264 (13%)
Query: 11 VRNKDNVARVRRDEAQAREEEKERERRVLLAQQEAR--TEFLRKKARHQNSLPE--LEAA 66
+R+KDN R ++EA+ ++ E R+ +A QEA + + Q +L E L+
Sbjct: 2234 LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEK 2293
Query: 67 EAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQT 126
+ + ELL++ K + +E +++KE+ + L T Q EA+
Sbjct: 2294 MQAVQEATRLKAEAELLQQQKELA---QEQARRLQEDKEQMAQQLAEETQGFQRTLEAER 2350
Query: 127 QPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSE 186
Q QL A E++K R+ + Q + Q + ++ +E
Sbjct: 2351 Q---RQLEMS--------AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2399
Query: 187 KQRPKEPPSLDQLR---------AERLRREAAERSR------AEALLARVQGRALQEGQP 231
++ + L AERLR AE R EA L +++ +Q Q
Sbjct: 2400 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQ 2459
Query: 232 EE--DETDDRRRRYNSQFNPQLAR 253
E+ ET ++ + S+ + L R
Sbjct: 2460 EQLLQETQALQQSFLSEKDSLLQR 2483
Score = 29.6 bits (65), Expect = 2.8
Identities = 54/255 (21%), Positives = 100/255 (39%), Gaps = 45/255 (17%)
Query: 14 KDNVARVRRDEAQAREEEKERER-RVLLAQQEARTEFLRKKARH-QNSLPELEAAEAGAP 71
++ V V+ E Q ++ + + ER R +A+ E E L+++A+ Q E++ +
Sbjct: 2403 QEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQL 2462
Query: 72 GSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWY 131
L + L E +++ + E+EK + ++ + + L + Q Q
Sbjct: 2463 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM--- 2519
Query: 132 QLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEK--------- 182
E+ + RL + M++ ++RQH +EG R ++E+
Sbjct: 2520 ----------------EQERQRL--VASMEE--ARRRQHEAEEGVRRKQEELQQLEQQRR 2559
Query: 183 -----EGSEKQRPKEPPSL--DQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDE 235
E QR +E L +Q RA E S+ A GR +G E E
Sbjct: 2560 QQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAE 2619
Query: 236 T----DDRRRRYNSQ 246
D RR+ ++Q
Sbjct: 2620 PEHSFDGLRRKVSAQ 2634
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.130 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,978,694
Number of Sequences: 37866
Number of extensions: 752876
Number of successful extensions: 9236
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 198
Number of HSP's successfully gapped in prelim test: 621
Number of HSP's that attempted gapping in prelim test: 6136
Number of HSP's gapped (non-prelim): 2586
length of query: 264
length of database: 18,247,518
effective HSP length: 100
effective length of query: 164
effective length of database: 14,460,918
effective search space: 2371590552
effective search space used: 2371590552
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.