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Search of human proteins with 24307965
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24307965 UBX domain containing 2 [Homo sapiens]
(508 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24307965 UBX domain containing 2 [Homo sapiens] 993 0.0
gi|21361517 UBX domain protein 1 [Homo sapiens] 99 1e-20
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 59 1e-08
gi|56549694 enabled homolog isoform a [Homo sapiens] 58 2e-08
gi|39930375 enabled homolog isoform b [Homo sapiens] 58 2e-08
gi|148746195 trichohyalin [Homo sapiens] 58 2e-08
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 57 4e-08
gi|5901948 FAS-associated factor 1 [Homo sapiens] 57 5e-08
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 57 5e-08
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 57 5e-08
gi|92859701 myosin VI [Homo sapiens] 56 9e-08
gi|10880975 hypothetical protein LOC57821 [Homo sapiens] 56 9e-08
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 55 1e-07
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 54 3e-07
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 54 3e-07
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 54 3e-07
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 54 3e-07
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 54 3e-07
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 54 4e-07
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 53 6e-07
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 53 7e-07
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 53 7e-07
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 52 1e-06
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 52 1e-06
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 52 2e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 52 2e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 52 2e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 52 2e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 52 2e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 52 2e-06
>gi|24307965 UBX domain containing 2 [Homo sapiens]
Length = 508
Score = 993 bits (2566), Expect = 0.0
Identities = 508/508 (100%), Positives = 508/508 (100%)
Query: 1 MLWFQGAIPAAIATAKRSGAVFVVFVAGDDEQSTQMAASWEDDKVTEASSNSFVAIKIDT 60
MLWFQGAIPAAIATAKRSGAVFVVFVAGDDEQSTQMAASWEDDKVTEASSNSFVAIKIDT
Sbjct: 1 MLWFQGAIPAAIATAKRSGAVFVVFVAGDDEQSTQMAASWEDDKVTEASSNSFVAIKIDT 60
Query: 61 KSEACLQFSQIYPVVCVPSSFFIGDSGIPLEVIAGSVSADELVTRIHKVRQMHLLKSETS 120
KSEACLQFSQIYPVVCVPSSFFIGDSGIPLEVIAGSVSADELVTRIHKVRQMHLLKSETS
Sbjct: 61 KSEACLQFSQIYPVVCVPSSFFIGDSGIPLEVIAGSVSADELVTRIHKVRQMHLLKSETS 120
Query: 121 VANGSQSESSVSTPSASFEPNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSS 180
VANGSQSESSVSTPSASFEPNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSS
Sbjct: 121 VANGSQSESSVSTPSASFEPNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSS 180
Query: 181 QEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKR 240
QEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKR
Sbjct: 181 QEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKR 240
Query: 241 KQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLA 300
KQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLA
Sbjct: 241 KQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLA 300
Query: 301 KQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNTYGNF 360
KQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNTYGNF
Sbjct: 301 KQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNTYGNF 360
Query: 361 SLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTASIVHSSSGDIWTLLGTVLY 420
SLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTASIVHSSSGDIWTLLGTVLY
Sbjct: 361 SLATMFPRREFTKEDYKKKLLDLELAPSASVVLLPAGRPTASIVHSSSGDIWTLLGTVLY 420
Query: 421 PFLAIWRLISNFLFSNPPPTQTSVRVTSSEPPNPASSSKSEKREPVRKRVLEKRGDDFKK 480
PFLAIWRLISNFLFSNPPPTQTSVRVTSSEPPNPASSSKSEKREPVRKRVLEKRGDDFKK
Sbjct: 421 PFLAIWRLISNFLFSNPPPTQTSVRVTSSEPPNPASSSKSEKREPVRKRVLEKRGDDFKK 480
Query: 481 EGKIYRLRTQDDGEDENNTWNGNSTQQM 508
EGKIYRLRTQDDGEDENNTWNGNSTQQM
Sbjct: 481 EGKIYRLRTQDDGEDENNTWNGNSTQQM 508
>gi|21361517 UBX domain protein 1 [Homo sapiens]
Length = 312
Score = 98.6 bits (244), Expect = 1e-20
Identities = 67/236 (28%), Positives = 119/236 (50%), Gaps = 23/236 (9%)
Query: 159 PTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEE 218
PTS + G E +G A +P+ ++R + +R+ + + +++ E+ + EE
Sbjct: 64 PTSSEQG----GLEGSGSAAGEGKPALSEEERQEQ-----TKRMLELVAQKQREREEREE 114
Query: 219 QREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAE 278
+ +++E +RR+ G+E+ +++ +E+ +R EER REKAE+ AAR+R++++I D+AE
Sbjct: 115 REALERERQRRRQGQELSAARQRLQEDEMRRAAEERRREKAEELAARQRVREKIERDKAE 174
Query: 279 RAARF----AKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSSFTN 334
RA ++ V + E KRE RIQ RLPDG+S T
Sbjct: 175 RAKKYGGSVGSQPPPVAPEPGPVPSSPSQEPPTKRE------YDQCRIQVRLPDGTSLTQ 228
Query: 335 QFPSDAPLEEARQFA----AQTVGNTYGNFSLATMFPRREFTKEDYKKKLLDLELA 386
F + L R + + +G L + FPRR F++ D ++ L +L +A
Sbjct: 229 TFRAREQLAAVRLYVELHRGEELGGGQDPVQLLSGFPRRAFSEADMERPLQELGMA 284
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 58.5 bits (140), Expect = 1e-08
Identities = 47/186 (25%), Positives = 89/186 (47%), Gaps = 10/186 (5%)
Query: 126 QSESSVSTPSASFEPNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSSQEPSG 185
+ +++ + S S + +++ E+S E+ + SD+ S +++ +
Sbjct: 127 KKQANKTASSGSSDKDSSAESSAPEEGEVSD----SDSNSSSSSSDSDSSSEDEEFHDGY 182
Query: 186 CSDQRPAEDLNIRVERLTKKLEER----REEKRKEEEQR-EIKKEIERRKTGKEMLDYKR 240
D E+ R+E++T+K E+ R EKR+ ++R EIKK+++ K KE + K+
Sbjct: 183 GEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKK-KEKKEKKK 241
Query: 241 KQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLA 300
KQEEE K+ L + + R K+ LD+ +A K + E + A LLA
Sbjct: 242 KQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLA 301
Query: 301 KQAEME 306
K+ ++
Sbjct: 302 KKQPLK 307
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 57.8 bits (138), Expect = 2e-08
Identities = 44/176 (25%), Positives = 88/176 (50%), Gaps = 10/176 (5%)
Query: 179 SSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDY 238
+SQ P+ + E+L I+ +L ++ ++ E+ + E +R ++ +ER + +E L+
Sbjct: 124 NSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLER 183
Query: 239 KRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVE----AAK 294
+R ++E+L + E + RE+ E +ER+++Q L+R ER R + ++E E +
Sbjct: 184 ERLEQEQLER---ERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLER 240
Query: 295 AAALLAKQAEMEVKRESYARER---STVARIQFRLPDGSSFTNQFPSDAPLEEARQ 347
+Q ++E ++ + RER S A P S + S+ L+ A Q
Sbjct: 241 ERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQ 296
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 57.8 bits (138), Expect = 2e-08
Identities = 44/176 (25%), Positives = 88/176 (50%), Gaps = 10/176 (5%)
Query: 179 SSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDY 238
+SQ P+ + E+L I+ +L ++ ++ E+ + E +R ++ +ER + +E L+
Sbjct: 124 NSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLER 183
Query: 239 KRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVE----AAK 294
+R ++E+L + E + RE+ E +ER+++Q L+R ER R + ++E E +
Sbjct: 184 ERLEQEQLER---ERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLER 240
Query: 295 AAALLAKQAEMEVKRESYARER---STVARIQFRLPDGSSFTNQFPSDAPLEEARQ 347
+Q ++E ++ + RER S A P S + S+ L+ A Q
Sbjct: 241 ERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQ 296
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 57.8 bits (138), Expect = 2e-08
Identities = 42/165 (25%), Positives = 86/165 (52%), Gaps = 10/165 (6%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELT 247
+QR + R ++L K+ EERR+++ K E++ +++ ++R + E L+ + ++E+ L
Sbjct: 564 EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEV--ERLEQEERREQRLK 621
Query: 248 KRMLEERNREK-AEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEME 306
+ EE R++ + ER +QQ+ ++ ER R + K E E + L ++ E E
Sbjct: 622 REEPEEERRQQLLKSEEQEERRQQQLRREQQER--REQRLKREEEEERLEQRLKREHEEE 679
Query: 307 VKRESYARERSTVA--RIQFRLPDGSSFTNQFPSDAPLEEARQFA 349
+ + A E A RI+ R+P + Q S+A +++ ++
Sbjct: 680 RREQELAEEEQEQARERIKSRIP---KWQWQLESEADARQSKVYS 721
Score = 54.3 bits (129), Expect = 3e-07
Identities = 40/129 (31%), Positives = 68/129 (52%), Gaps = 12/129 (9%)
Query: 190 RPAEDLNIRVERLTKKLEERREEKRKEEEQRE--IKKEIERRKTGKEMLDYKRKQEEELT 247
R + L E ++L +R EEKR E+E+RE +K+E E R+ D K+EEE
Sbjct: 533 RSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERR------DQLLKREEERR 586
Query: 248 KRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEV 307
++ L+ E+ E R RE +++ L++ ER + K +EE E + LL + + E
Sbjct: 587 QQRLKREQEERLEQRLKREEVER---LEQEERREQRLK-REEPEEERRQQLLKSEEQEER 642
Query: 308 KRESYARER 316
+++ RE+
Sbjct: 643 RQQQLRREQ 651
Score = 52.4 bits (124), Expect = 1e-06
Identities = 41/124 (33%), Positives = 65/124 (52%), Gaps = 14/124 (11%)
Query: 198 RVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNRE 257
R +RL ++ EERR+ ++EEE + E ERRK KR QEEE +R L+ E
Sbjct: 443 REQRLKREQEERRDWLKREEETE--RHEQERRKQ-----QLKRDQEEERRERWLK---LE 492
Query: 258 KAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERS 317
+ E R +ER +QQ+ ++ ER + K +EE E + ++E +++RE R
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRL----RSEQQLRREQEERREQ 548
Query: 318 TVAR 321
+ R
Sbjct: 549 LLKR 552
Score = 51.6 bits (122), Expect = 2e-06
Identities = 35/139 (25%), Positives = 72/139 (51%), Gaps = 5/139 (3%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIE-RRKTGKEMLDYKRKQEEELT 247
QR ++ ++ +L ++ E RRE + +E++Q+ +++E + RRK +E + + ++ E+
Sbjct: 268 QRELQEEEEQLRKLERQ-ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 248 KRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQ---AE 304
+R +E RE+ R ER +QQ+ ++ E +E+ E + L +Q E
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 305 MEVKRESYARERSTVARIQ 323
+++RE R + R Q
Sbjct: 387 QQLRREQQLRREQQLRREQ 405
Score = 50.1 bits (118), Expect = 5e-06
Identities = 37/135 (27%), Positives = 70/135 (51%), Gaps = 11/135 (8%)
Query: 200 ERLTKKLEERREEKRKEEEQ-REIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREK 258
E+L ++ +R+ E ++EEEQ R+++++ RR+ +E +R + E+ +R EE RE+
Sbjct: 258 EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQ 317
Query: 259 AEDRAAR--------ERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRE 310
E+R + ER +QQ+ ++ ER R + + E E + L ++ E E + +
Sbjct: 318 QEERREQQERREQQEERREQQLRREQEER--REQQLRREQEEERREQQLRREQEEERREQ 375
Query: 311 SYARERSTVARIQFR 325
RE+ Q R
Sbjct: 376 QLRREQQLRREQQLR 390
Score = 50.1 bits (118), Expect = 5e-06
Identities = 32/123 (26%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Query: 204 KKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRA 263
K+ EERRE++ + EQ+E +++ E R+ + + + ++E++L + EER ++
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 264 ARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQ---AEMEVKRESYARERSTVA 320
ER +QQ L R ++ R + + E + + L +Q E +++RE R +
Sbjct: 369 EEERREQQ--LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 321 RIQ 323
R Q
Sbjct: 427 REQ 429
Score = 48.5 bits (114), Expect = 1e-05
Identities = 45/165 (27%), Positives = 76/165 (46%), Gaps = 19/165 (11%)
Query: 181 QEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKR 240
QE Q E R ++L ++ + RRE++ + E+Q ++++ R + + +R
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427
Query: 241 KQEEE-------------LTKRMLEER----NREKAEDRAARERIKQQIALDR-AERAAR 282
+QEEE KR EER RE+ +R +ER KQQ+ D+ ER R
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 283 FAKTKEEVEAAKAAALLAK-QAEMEVKRESYARERSTVARIQFRL 326
+ K +EE + + + E E +RE + + R+Q RL
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRL 532
Score = 48.5 bits (114), Expect = 1e-05
Identities = 36/142 (25%), Positives = 71/142 (50%), Gaps = 9/142 (6%)
Query: 193 EDLNIRVERLTKKLEERREEKRKEEEQREIKKEI---ERRKTGKEMLDYKRKQEEELTK- 248
E+ +R ER ++L+ER + R+EEE ++ ++++ ER ++ L+ + ++EEEL +
Sbjct: 1030 EEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQE 1089
Query: 249 -----RMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQA 303
R E+ R + +R RE + Q ++ R R + ++E+E +Q
Sbjct: 1090 EEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE 1149
Query: 304 EMEVKRESYARERSTVARIQFR 325
E ++ RE + R Q+R
Sbjct: 1150 EEQLLREEPEKRRRQELERQYR 1171
Score = 48.1 bits (113), Expect = 2e-05
Identities = 39/151 (25%), Positives = 72/151 (47%), Gaps = 5/151 (3%)
Query: 200 ERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKA 259
ER + L+ EE+R+++E+RE + E+ + ++ L KR++EEE ++ L + +
Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRL--KRQEEEERLQQRLRSEQQLRR 540
Query: 260 EDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQ--AEMEVKRESYARERS 317
E RE++ ++ R E+ R + K E E + L ++ + +KRE R
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600
Query: 318 TVARIQF-RLPDGSSFTNQFPSDAPLEEARQ 347
+ R + RL + + P EE RQ
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQ 631
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/145 (24%), Positives = 73/145 (50%), Gaps = 11/145 (7%)
Query: 190 RPAEDLNIRVERLTKKLEERREEK----RKEEEQREIKKEIERRKTGKEMLDYK------ 239
R E L +R + +K ++RRE + ++EEE+ K+E RK +++ + +
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 240 -RKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAAL 298
+++EE+L K +E RE+ E+ ++R++++ L R + R + +E E +
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ 330
Query: 299 LAKQAEMEVKRESYARERSTVARIQ 323
++ E +++RE R + R Q
Sbjct: 331 QEERREQQLRREQEERREQQLRREQ 355
Score = 47.8 bits (112), Expect = 2e-05
Identities = 31/142 (21%), Positives = 72/142 (50%), Gaps = 4/142 (2%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELT 247
+QR + R + L ++ E R E+ + ++Q + +E ERR+ ++ + +R++++E
Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERR 503
Query: 248 KRMLEERNREKAEDRAAR----ERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQA 303
++ L E+ E R R ER++Q++ ++ R + + ++ ++ + L ++
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563
Query: 304 EMEVKRESYARERSTVARIQFR 325
E +KRE R + R + R
Sbjct: 564 EQRLKREQEERRDQLLKREEER 585
Score = 46.2 bits (108), Expect = 7e-05
Identities = 40/199 (20%), Positives = 98/199 (49%), Gaps = 15/199 (7%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREE--KRKEEEQREIKKEIERRKTGKEMLDYKRK-QEE 244
++R ++ + + + L+ER E+ +R+E +++ ++E+ ++ G++ L+ +++ + +
Sbjct: 1327 EKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQ 1386
Query: 245 ELTKRML--------EERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAA 296
E ++ L +ER ++ +DR + R ++Q L R ER +F + +++V +
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ-QLSRQERDRKFREEEQQVRRQERE 1445
Query: 297 ALLAKQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTVGNT 356
++ E ++++E + + R +Q R + Q LEE +Q Q
Sbjct: 1446 RKFLEE-EQQLRQERHRKFREEEQLLQER--EEQQLHRQERDRKFLEEEQQLRRQERDRK 1502
Query: 357 YGNFSLATMFPRREFTKED 375
+ L + P R+F +E+
Sbjct: 1503 FREQELRSQEPERKFLEEE 1521
Score = 45.4 bits (106), Expect = 1e-04
Identities = 47/156 (30%), Positives = 69/156 (44%), Gaps = 15/156 (9%)
Query: 207 EERREEKRKEEEQREIKKE-IERRKTGKEMLDYKRKQEEE----LTKRMLEERNRE---- 257
EERR++ K EEQ E +++ + R + + KR++EEE KR EE RE
Sbjct: 627 EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELA 686
Query: 258 KAEDRAARERIKQQIALDR----AERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYA 313
+ E ARERIK +I + +E AR +K + +Q E +RES
Sbjct: 687 EEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL 746
Query: 314 --RERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQ 347
+E R Q FT Q+ ++ E RQ
Sbjct: 747 QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782
Score = 45.4 bits (106), Expect = 1e-04
Identities = 30/130 (23%), Positives = 63/130 (48%), Gaps = 13/130 (10%)
Query: 198 RVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNRE 257
++ER +K +RR+ RK +E++++ +E K ++ D K ++EE+L + E+ R
Sbjct: 1298 QLEREEQKEAKRRD--RKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR 1355
Query: 258 KAEDRAARER-----------IKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEME 306
+ DR RE ++++ L R ER +F K ++++ + L + + +
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
Query: 307 VKRESYARER 316
+ E R
Sbjct: 1416 FREEEQQLSR 1425
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/133 (24%), Positives = 69/133 (51%), Gaps = 12/133 (9%)
Query: 190 RPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKR 249
+PA +R E+ + L+E EE ++EE ++ ++E ER+ +E L +++EE+L +
Sbjct: 892 KPALQEQLRKEQ--QLLQEEEEELQREEREKRRRQEQERQYREEEQL---QQEEEQLLRE 946
Query: 250 MLEERNREKAEDRAARERIKQQ-------IALDRAERAARFAKTKEEVEAAKAAALLAKQ 302
E+R R++ E + +++ QQ ++ R R K +EE E + L ++
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
Query: 303 AEMEVKRESYARE 315
+ +R+ + R+
Sbjct: 1007 EREKRRRQEWERQ 1019
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/129 (27%), Positives = 64/129 (49%), Gaps = 16/129 (12%)
Query: 201 RLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQE----------EELTKRM 250
R ++ + R EE+ ++EE++ +++E E+R+ + Y++K E EE KR
Sbjct: 983 RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRR 1042
Query: 251 LEERNREKAEDRAARERIKQQIALDRAERAARFAK---TKEEVEAAKAAALLAKQAEMEV 307
L+ER R+ E+ ++ +Q + +R R + + KEE + LL ++ E
Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPE--- 1099
Query: 308 KRESYARER 316
KR RER
Sbjct: 1100 KRRRQERER 1108
Score = 43.5 bits (101), Expect = 5e-04
Identities = 32/130 (24%), Positives = 69/130 (53%), Gaps = 9/130 (6%)
Query: 193 EDLNIRVERLTKKLEERREEKRKEEEQR---EIKKEIERRKTGKEMLDYKRKQEEELTKR 249
E+ + ER ++ E R ++ R+E+E+R ++++E E + +++ +R+QEEE ++
Sbjct: 319 EERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQL---RREQEEERREQ 375
Query: 250 MLEERNREKAEDRAARE-RIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAE--ME 306
L + + E + RE +++++ L R ++ R + + E + + L +Q E E
Sbjct: 376 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435
Query: 307 VKRESYARER 316
K E RE+
Sbjct: 436 QKHEQERREQ 445
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/130 (23%), Positives = 69/130 (53%), Gaps = 6/130 (4%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELT 247
D++ ED + ER ++L + +++ EE+ +++++ ER + + D K ++EE+L
Sbjct: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ-EREQQLRHDRDRKFREEEQLL 1676
Query: 248 KRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEM-- 305
+ E++ R + DR RE +Q L R ER +F + ++++ + ++ ++
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQ---LRRQERERKFLQEEQQLRRQELERKFREEEQLRQ 1733
Query: 306 EVKRESYARE 315
E ++E R+
Sbjct: 1734 ETEQEQLRRQ 1743
Score = 43.1 bits (100), Expect = 6e-04
Identities = 29/136 (21%), Positives = 71/136 (52%), Gaps = 2/136 (1%)
Query: 181 QEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKR 240
QE +R + R ++L ++ EERRE++ + E++ E +++ RR+ +E + +
Sbjct: 318 QEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQL 377
Query: 241 KQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLA 300
++E++L R ++ RE+ R + R +QQ+ ++ R + + ++++ +
Sbjct: 378 RREQQL--RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435
Query: 301 KQAEMEVKRESYARER 316
++ E E + + RE+
Sbjct: 436 QKHEQERREQRLKREQ 451
Score = 42.7 bits (99), Expect = 8e-04
Identities = 30/144 (20%), Positives = 75/144 (52%), Gaps = 11/144 (7%)
Query: 193 EDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLE 252
E+ +R + +K E ++ R++E +R+ +E ++ + ++ L+ K ++EE+L + +
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLR--RQELERKFREEEQLRQETEQ 1737
Query: 253 ERNREK-------AEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEM 305
E+ R + E++ ER +QQ L R ER +F + ++ + + L +++++
Sbjct: 1738 EQLRRQERYRKILEEEQLRPEREEQQ--LRRQERDRKFREEEQLRQEREEQQLRSQESDR 1795
Query: 306 EVKRESYARERSTVARIQFRLPDG 329
+ + E R+ +++ + DG
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDG 1819
Score = 42.4 bits (98), Expect = 0.001
Identities = 54/183 (29%), Positives = 79/183 (43%), Gaps = 39/183 (21%)
Query: 168 ATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEE----RREEKRKE------- 216
ATG + A + S D+R ED R E ++LEE RR +KR+E
Sbjct: 92 ATGLDEEKRARCDGKESLLQDRRQEEDQR-RFEPRDRQLEEEPGQRRRQKRQEQERELAE 150
Query: 217 -EEQREIKKEIERRKTGK--EMLDYKRKQEEELTKRMLEE-------------------- 253
EEQ E ++ +E+R + E L +R++ +E +R EE
Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL 210
Query: 254 RNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYA 313
R RE E R KQQ R ER R + +EE E K +L K+ E +++ E
Sbjct: 211 RRRELLELRRKGREEKQQ---QRRERQDRVFQEEEEKEWRKRETVLRKEEE-KLQEEEPQ 266
Query: 314 RER 316
R+R
Sbjct: 267 RQR 269
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/118 (22%), Positives = 61/118 (51%), Gaps = 12/118 (10%)
Query: 198 RVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNRE 257
++ R + + R++ RK E+ ++++E E ++ ++ D K + EE+ +R +ER
Sbjct: 1539 QLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFM 1598
Query: 258 KAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARE 315
+ E + R+ +QQ+ R ER +F + ++ LL ++ E ++ R+ R+
Sbjct: 1599 EDEQQLRRQEGQQQL---RQERDRKFREDEQ---------LLQEREEQQLHRQERDRK 1644
Score = 42.0 bits (97), Expect = 0.001
Identities = 31/125 (24%), Positives = 65/125 (52%), Gaps = 3/125 (2%)
Query: 193 EDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLE 252
E+ +R ER ++L R+E RK E+ ++++E E ++ + D K ++EE+L + E
Sbjct: 1751 EEEQLRPEREEQQLR-RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809
Query: 253 ERNREKAEDRAARERIKQQIALDRAERAARFAKTKE-EVEAAKAAALLAKQAEMEVKRES 311
++ R + D R ++Q+ L+ E+ R + ++ E A +++ E E+ +E
Sbjct: 1810 QQLRPQQRDGKYRWE-EEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEE 1868
Query: 312 YARER 316
+ R
Sbjct: 1869 EQKRR 1873
Score = 41.2 bits (95), Expect = 0.002
Identities = 38/147 (25%), Positives = 72/147 (48%), Gaps = 17/147 (11%)
Query: 189 QRPAEDLNIRVERLTKKLEE-----RREEKRKEEEQREIKKEIERRKTGKEMLDYKR--- 240
Q E+L R ER ++ +E R EE+ ++EE++ +++E E+R+ + Y++
Sbjct: 907 QEEEEELQ-REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
Query: 241 --KQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAAL 298
++EE+L E+R R++ E + E QQ ++ R R + ++E E
Sbjct: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ-EEEQLLREEREKRRRQEWERQ----- 1019
Query: 299 LAKQAEMEVKRESYARERSTVARIQFR 325
K+ E++ + E RE R+Q R
Sbjct: 1020 YRKKDELQQEEEQLLREEREKRRLQER 1046
Score = 41.2 bits (95), Expect = 0.002
Identities = 35/138 (25%), Positives = 71/138 (51%), Gaps = 7/138 (5%)
Query: 193 EDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLE 252
E+ +R E ++L R+E RK E+ +++ E E ++ ++ D K ++EE+L + E
Sbjct: 1727 EEEQLRQETEQEQLR-RQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE 1785
Query: 253 ERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESY 312
++ R + DR RE ++Q+ +R E+ R + ++ + L ++ E +++E
Sbjct: 1786 QQLRSQESDRKFRE--EEQLRQEREEQQLR-PQQRDGKYRWEEEQLQLEEQEQRLRQE-- 1840
Query: 313 ARERSTVARIQFRLPDGS 330
R+R A QF + S
Sbjct: 1841 -RDRQYRAEEQFATQEKS 1857
Score = 40.8 bits (94), Expect = 0.003
Identities = 29/125 (23%), Positives = 62/125 (49%), Gaps = 7/125 (5%)
Query: 198 RVERLTKKLEE----RREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEE 253
R ER K LEE R+E RK E+ ++ +E E ++ ++ D K +EE+ +R +
Sbjct: 1441 RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500
Query: 254 RNREKAEDRA---ARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRE 310
R + E R+ R+ ++++ L R +R +F + ++++ + + + + + E
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Query: 311 SYARE 315
R+
Sbjct: 1561 EQLRQ 1565
Score = 40.8 bits (94), Expect = 0.003
Identities = 32/129 (24%), Positives = 62/129 (48%), Gaps = 4/129 (3%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELT 247
D++ E+ +R ER ++L +E RK E+ ++++E E ++ + D K + EEE
Sbjct: 1770 DRKFREEEQLRQEREEQQLRS-QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE-- 1826
Query: 248 KRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEV 307
+ LEE+ + ++R + R ++Q A R +EE E + K E +
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEE-EQKRRQERERKLREEHI 1885
Query: 308 KRESYARER 316
+R+ +R
Sbjct: 1886 RRQQKEEQR 1894
Score = 40.4 bits (93), Expect = 0.004
Identities = 32/133 (24%), Positives = 68/133 (51%), Gaps = 7/133 (5%)
Query: 190 RPAEDLNIRVERLTKKL-EERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTK 248
R E+L E+L ++ E+RR ++R+ + + E + + E + +E + +R+Q EL +
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ--ELER 1138
Query: 249 RMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVK 308
+ EE ++ E++ RE +++ R + R + +EE++ + L +Q + +
Sbjct: 1139 QYREEEEVQQEEEQLLREEPEKR----RRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194
Query: 309 RESYARERSTVAR 321
RE RE + R
Sbjct: 1195 RERQYREEEELQR 1207
Score = 40.0 bits (92), Expect = 0.005
Identities = 42/150 (28%), Positives = 70/150 (46%), Gaps = 28/150 (18%)
Query: 182 EPSGCSDQRPAEDLNIRVERLTKKLEERREEKRK----------EEEQ--REIKKEIERR 229
E S D++ +DL L ++ E RE++R+ EEEQ RE +KE +RR
Sbjct: 1254 EDSQLRDRQSQQDLQ---HLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR 1310
Query: 230 KTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAE----RAARFAK 285
D K ++E++L + EE+ R + DR RE ++Q+ +R E R R K
Sbjct: 1311 -------DRKSQEEKQLLREEREEKRRRQETDRKFRE--EEQLLQEREEQPLRRQERDRK 1361
Query: 286 TKEEVEAAKAAALLAKQAEMEVKRESYARE 315
+EE + + E ++R+ R+
Sbjct: 1362 FREEELRHQEQGRKFLEEEQRLRRQERERK 1391
Score = 39.7 bits (91), Expect = 0.007
Identities = 39/181 (21%), Positives = 69/181 (38%), Gaps = 4/181 (2%)
Query: 145 ENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTK 204
E Q+R IP A +S ++ ++ Q E R L
Sbjct: 689 EQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQW 748
Query: 205 KLEERREEKRKEEEQREIK----KEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAE 260
+ EER +++EEEQR + E+ + G++ L + E+ +++ E +++ +
Sbjct: 749 QEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQ 808
Query: 261 DRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVA 320
E K+Q R ER +EE + + Q E + +E R RS
Sbjct: 809 RFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ 868
Query: 321 R 321
R
Sbjct: 869 R 869
Score = 39.3 bits (90), Expect = 0.009
Identities = 34/148 (22%), Positives = 62/148 (41%), Gaps = 19/148 (12%)
Query: 200 ERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRM--------L 251
ERL ++L+ EE+R+E+E E ++E R + + ++ + E E R
Sbjct: 666 ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRK 725
Query: 252 EERNREKAEDRAARERIKQQIALDRAERAARFAKTKE-----------EVEAAKAAALLA 300
+E R + E R R + ++ ERA R + +E E ++ + L+
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785
Query: 301 KQAEMEVKRESYARERSTVARIQFRLPD 328
+ + +RE R R Q LP+
Sbjct: 786 ARPPLREQRERQLRAEERQQREQRFLPE 813
Score = 38.9 bits (89), Expect = 0.011
Identities = 31/145 (21%), Positives = 67/145 (46%), Gaps = 2/145 (1%)
Query: 181 QEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKR 240
QE + ++ E + R+ + +LE + ++ + R K+E +RR+ +E + +R
Sbjct: 683 QELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR--QEQEEKRR 740
Query: 241 KQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLA 300
++E EL + E +R++ E+ R+ Q A +++ER + + + + L A
Sbjct: 741 RRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRA 800
Query: 301 KQAEMEVKRESYARERSTVARIQFR 325
++ + +R E R Q R
Sbjct: 801 EERQQREQRFLPEEEEKEQRRRQRR 825
Score = 37.4 bits (85), Expect = 0.032
Identities = 42/182 (23%), Positives = 72/182 (39%), Gaps = 30/182 (16%)
Query: 172 ESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEE--RREEKRKEEEQREIKKEIERR 229
E +E S ++ D R E L ++ +E REE+R EEEQ + K E
Sbjct: 143 EQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETE 202
Query: 230 K-------TGKEMLDYKRKQEEELTKRMLEERNR-----------------EKAEDRAAR 265
+ +E+L+ +RK EE ++ E ++R K E++
Sbjct: 203 EFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE 262
Query: 266 ERIKQQIALDRAERAARFAKT----KEEVEAAKAAALLAKQAEMEVKRESYARERSTVAR 321
E ++Q L E R + +E E + L ++ ++ K+E RE+ R
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322
Query: 322 IQ 323
Q
Sbjct: 323 EQ 324
Score = 37.4 bits (85), Expect = 0.032
Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 19/155 (12%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQR----EIKKEIERRKTGKEMLDYKRKQEE 244
+R + L+ R ++ + R E+R++ EQR E +KE RR+ + + + +EE
Sbjct: 778 ERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE 837
Query: 245 ELTKR-------------MLEERNREKAEDRAARERIKQQIALDRAERA-ARFAKTKEEV 290
E +R + E++ R +++++ ++ + Q+ +R R +AK +
Sbjct: 838 EQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQE 897
Query: 291 EAAKAAALLAKQAEMEVKRESYARERSTVARIQFR 325
+ K LL ++ E E++RE + R Q+R
Sbjct: 898 QLRKEQQLLQEEEE-ELQREEREKRRRQEQERQYR 931
Score = 37.4 bits (85), Expect = 0.032
Identities = 23/93 (24%), Positives = 54/93 (58%), Gaps = 13/93 (13%)
Query: 198 RVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRK-----------QEEEL 246
R ER K LEE ++ +R+E +++ ++E+ ++ ++ L+ +++ QEE+
Sbjct: 1480 RQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQ 1539
Query: 247 TKRMLEERNREKAEDRAARERIKQQIALDRAER 279
+R +ER +++ +DR + R ++Q+ +R E+
Sbjct: 1540 LRR--QERGQQRRQDRDRKFREEEQLRQEREEQ 1570
Score = 37.0 bits (84), Expect = 0.042
Identities = 33/143 (23%), Positives = 67/143 (46%), Gaps = 11/143 (7%)
Query: 193 EDLNIRVERLTKKLEE-RREEKRKEEEQRE----IKKEIERRKTGKEMLDYK-----RKQ 242
E+ +R ER ++ +E R+ ++K+E Q+E +++E E+R+ + Y+ +++
Sbjct: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQE 1059
Query: 243 EEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQ 302
EE+L E R R++ E + +E QQ + +E + L ++
Sbjct: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119
Query: 303 AEMEVKRESYARERSTVARIQFR 325
E ++ E R R + R Q+R
Sbjct: 1120 EEQLLREEREKRRRQELER-QYR 1141
Score = 37.0 bits (84), Expect = 0.042
Identities = 35/145 (24%), Positives = 73/145 (50%), Gaps = 8/145 (5%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQ--EEE 245
++R ++L R R +++++ E+ +EE ++ ++E+ER+ +E L + +Q EE
Sbjct: 1129 EKRRRQELE-RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187
Query: 246 LTKRMLEERNREKAEDRAARERIKQQIALDRAERA-ARFAKTKEEVEAAKAAALLAKQAE 304
KR +ER R+ E+ + + ++Q D +R+ ++ E+ A + + K E
Sbjct: 1188 QEKRR-QERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 305 MEVKR---ESYARERSTVARIQFRL 326
E R +S R+R + +Q L
Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLL 1271
Score = 36.6 bits (83), Expect = 0.055
Identities = 33/141 (23%), Positives = 73/141 (51%), Gaps = 15/141 (10%)
Query: 188 DQRPAEDLNIRVERLTKKLE-ERREEKRKEEEQREIKKEIER----------RKTGKEML 236
D++ E+ +R ER ++L + R+ K + EEQ+ ++E ER R+ G++ L
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Query: 237 DYKRKQEEELTKRMLEERNREKAEDRAARER--IKQQIALDRAERAARFAKTKEEVEAAK 294
+R ++ +++L+ER ++ R R+R ++++ L R ER + ++ + +
Sbjct: 1614 RQERDRKFREDEQLLQEREEQQLH-RQERDRKFLEEEPQLRRQEREQQLRHDRDR-KFRE 1671
Query: 295 AAALLAKQAEMEVKRESYARE 315
LL + E +++R+ R+
Sbjct: 1672 EEQLLQEGEEQQLRRQERDRK 1692
Score = 35.8 bits (81), Expect = 0.095
Identities = 27/97 (27%), Positives = 56/97 (57%), Gaps = 8/97 (8%)
Query: 193 EDLNIRVERLTKKLEE-RREEKRKEEEQRE----IKKEIERRKTGKEMLDYKRKQEEELT 247
E+ +R ER ++ +E R+ + +EE Q+E +++E E+R+ ++ L+ + ++EEEL
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR--RQELERQYREEEELQ 1177
Query: 248 KRMLEERNREKAEDRAARER-IKQQIALDRAERAARF 283
+ + E+ + R RER +++ L R +R R+
Sbjct: 1178 QEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRY 1214
Score = 35.8 bits (81), Expect = 0.095
Identities = 27/114 (23%), Positives = 56/114 (49%), Gaps = 10/114 (8%)
Query: 209 RREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERI 268
R+E RK E ++ +E E ++ ++ D K +EE +R +ER ++ DR + R
Sbjct: 1614 RQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR--QEREQQLRHDRDRKFRE 1671
Query: 269 KQQI-------ALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARE 315
++Q+ L R ER +F + ++++ + Q E +++R+ R+
Sbjct: 1672 EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL-QEEQQLRRQELERK 1724
Score = 35.4 bits (80), Expect = 0.12
Identities = 27/114 (23%), Positives = 61/114 (53%), Gaps = 13/114 (11%)
Query: 187 SDQRPAEDLNIRVERLTKKL--EERREEKRKEEEQREIKKEIERRKTGKE---------- 234
SD++ E+ +R ER ++L ++R + R EEEQ +++++ +R + ++
Sbjct: 1793 SDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFA 1852
Query: 235 MLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKE 288
+ R++E+EL + E++ R++ E + E I++Q ++ R K++E
Sbjct: 1853 TQEKSRREEQELWQEE-EQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQE 1905
Score = 35.0 bits (79), Expect = 0.16
Identities = 24/130 (18%), Positives = 63/130 (48%), Gaps = 8/130 (6%)
Query: 189 QRPAEDLNIRVERLTKKLEERR---EEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEE 245
+R D R + L + ER+ EE++ +QR+ K E ++ ++ +R+Q+ +
Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD 1554
Query: 246 LTKRMLEERNREKAEDRAARERIKQQIALD-----RAERAARFAKTKEEVEAAKAAALLA 300
R E+ +E+ E + +R+ ++ L+ R E+ +F + ++++ + L
Sbjct: 1555 RKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLR 1614
Query: 301 KQAEMEVKRE 310
++ + + + +
Sbjct: 1615 QERDRKFRED 1624
Score = 35.0 bits (79), Expect = 0.16
Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 29/141 (20%)
Query: 198 RVERLTKKLEER-------REEKRKEEEQREIKKEIERRKTGKEM------LDYKRKQEE 244
R ER K LEE RE++ + + R+ ++E + + G+E D K ++EE
Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEE 1697
Query: 245 ELTKRMLEERNREKAEDRAAR----------ERIKQQIALDRAERAARFAKTKEEVEAAK 294
+ +R ER + E + R E+++Q+ ++ R R+ K EE +
Sbjct: 1698 QQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ--- 1754
Query: 295 AAALLAKQAEMEVKRESYARE 315
L ++ E +++R+ R+
Sbjct: 1755 ---LRPEREEQQLRRQERDRK 1772
Score = 34.3 bits (77), Expect = 0.28
Identities = 25/108 (23%), Positives = 52/108 (48%), Gaps = 2/108 (1%)
Query: 189 QRPAEDLNIRVERLTKKLEER--REEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEEL 246
+R + R E ++ EE+ REE+ K Q ++ E + +E R++ E+
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161
Query: 247 TKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAK 294
++ LE + RE+ E + E++ ++ R + R + +EE++ K
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Score = 32.7 bits (73), Expect = 0.80
Identities = 29/145 (20%), Positives = 68/145 (46%), Gaps = 10/145 (6%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYK-RKQEEELT 247
QR + ++ ++L+ R ++ +EE+ ++++ ERR++ ++ D K R Q EE
Sbjct: 823 QRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEER 882
Query: 248 KRM---------LEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAAL 298
KR L+E+ R++ + E Q+ ++ R + + +EE + +
Sbjct: 883 KRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQ 942
Query: 299 LAKQAEMEVKRESYARERSTVARIQ 323
L ++ + +R+ R+ ++Q
Sbjct: 943 LLREEREKRRRQERERQYRKDKKLQ 967
Score = 32.0 bits (71), Expect = 1.4
Identities = 37/146 (25%), Positives = 70/146 (47%), Gaps = 17/146 (11%)
Query: 193 EDLNIRVERLTKKLEERREEKR------KEEEQREIKKEIERRKTGKEMLDYK-----RK 241
E+ +R ER ++ +ER + R ++EEQ + +E E+R+ + Y+ ++
Sbjct: 940 EEQLLREEREKRRRQERERQYRKDKKLQQKEEQL-LGEEPEKRRRQEREKKYREEEELQQ 998
Query: 242 QEEELTKRMLEERNREKAED--RAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALL 299
+EE+L + E+R R++ E R E +++ L R ER R + +E + L
Sbjct: 999 EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKR--RLQERERQYREEEEL 1056
Query: 300 AKQAEMEVKRESYARERSTVARIQFR 325
++ E + E R R + R Q+R
Sbjct: 1057 QQEEEQLLGEERETRRRQELER-QYR 1081
Score = 30.8 bits (68), Expect = 3.0
Identities = 31/135 (22%), Positives = 63/135 (46%), Gaps = 4/135 (2%)
Query: 193 EDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYK-RKQEEELTKRML 251
++L E + ER ++ ++EE+ ++++ ERR++ ++ D K R Q EE KR
Sbjct: 829 KELQFLEEEEQLQRRERAQQLQEEED--GLQEDQERRRSQEQRRDQKWRWQLEEERKRRR 886
Query: 252 EERNREKA-EDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRE 310
+ A +++ +E+ Q + +R R + ++E E +Q E ++ RE
Sbjct: 887 HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Query: 311 SYARERSTVARIQFR 325
+ R Q+R
Sbjct: 947 EREKRRRQERERQYR 961
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 57.0 bits (136), Expect = 4e-08
Identities = 56/228 (24%), Positives = 100/228 (43%), Gaps = 20/228 (8%)
Query: 128 ESSVSTPSASFE---PNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSSQEPS 184
+SS+ P P + S+ + E P + +S +A + SQ
Sbjct: 188 QSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAE 247
Query: 185 GCSDQR-PAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQE 243
DQ P+ +L +R +R K EE EE+ +EE+ E + + E +K+ + + + K+E
Sbjct: 248 EEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEE 307
Query: 244 -EELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQ 302
EE+ + EE E+ + R+ + + ER RF +++EE A+ + L +Q
Sbjct: 308 GEEIPRVKPEEMMDERPKTRSQEQEV--------LERGGRFTRSQEE---ARKSHLARQQ 356
Query: 303 AEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAA 350
E E+K S E + + G ++ PS L E R+ A+
Sbjct: 357 QEKEMKTTSPLEEEER----EIKSSQGLKEKSKSPSPPRLTEDRKKAS 400
Score = 42.4 bits (98), Expect = 0.001
Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 25/132 (18%)
Query: 191 PAEDLNIRVERLTKKLEERRE-EKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKR 249
P D I V++ ++ E +E EKR++E++ E +KE E+ + +R++ E ++
Sbjct: 1228 PLTDSQI-VQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRE 1286
Query: 250 MLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKR 309
ER RE+ DR R+R +++ ER R + KR
Sbjct: 1287 RDRERERERERDRGDRDRDRERDRERGRERDRR-----------------------DTKR 1323
Query: 310 ESYARERSTVAR 321
S +R RST R
Sbjct: 1324 HSRSRSRSTPVR 1335
Score = 34.7 bits (78), Expect = 0.21
Identities = 22/88 (25%), Positives = 45/88 (51%), Gaps = 11/88 (12%)
Query: 205 KLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAA 264
+ E+R +E+ E+ E ++E+ERR+ + ++ R + E R+R ++ DR
Sbjct: 1132 RAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVRE------GPRSRSRSRDRRR 1185
Query: 265 RERIKQQIALDRAERAARFAKTKEEVEA 292
+ER K + +++ + K +EE A
Sbjct: 1186 KERAK-----SKEKKSEKKEKAQEEPPA 1208
Score = 33.5 bits (75), Expect = 0.47
Identities = 30/122 (24%), Positives = 59/122 (48%), Gaps = 20/122 (16%)
Query: 203 TKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEE--------ELTKRMLEER 254
++ + RR+E+ K +E++ KKE + + ++LD ++ + LT + ++
Sbjct: 1178 SRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQK 1237
Query: 255 NREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYAR 314
E+AE A+ER K++ + E+ R + + E +Q E E KR ++R
Sbjct: 1238 EAERAE--RAKEREKRRKEQEEEEQKEREKEAERERN---------RQLERE-KRREHSR 1285
Query: 315 ER 316
ER
Sbjct: 1286 ER 1287
>gi|5901948 FAS-associated factor 1 [Homo sapiens]
Length = 650
Score = 56.6 bits (135), Expect = 5e-08
Identities = 50/220 (22%), Positives = 99/220 (45%), Gaps = 30/220 (13%)
Query: 175 GHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKE 234
G +S++ + ++L +R+ + +++E K+E++RE ++ +
Sbjct: 456 GKRSSNEVLNVIQGNTTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENV-------- 507
Query: 235 MLDYKRKQEEELTKRMLEERNREKAEDRAARERIK-QQIALDRAERAARFAKTKEEVEAA 293
KR+Q+E + +R + +A +R E+ + +QI KE+ E
Sbjct: 508 ----KREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIR-------------KEQEEER 550
Query: 294 KAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQFAAQTV 353
+A L +QA +E A V++++ R P G +F + L+ F A
Sbjct: 551 EAIRLSLEQALPPEPKEENAEP---VSKLRIRTPSGEFLERRFLASNKLQIVFDFVASK- 606
Query: 354 GNTYGNFSLATMFPRREFTKEDYKKKLLDLELAPSASVVL 393
G + + L + FPRR+ T+ D K LL+++L P ++ L
Sbjct: 607 GFPWDEYKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFL 646
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 56.6 bits (135), Expect = 5e-08
Identities = 41/185 (22%), Positives = 83/185 (44%), Gaps = 9/185 (4%)
Query: 145 ENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTK 204
E + + +I ++ + E A ++++ +R E+ R+ L +
Sbjct: 594 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 653
Query: 205 KLEERREE----KRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAE 260
+ EERR + K+KEEEQ ++K E ++ ++ R+QE +R +ER ++
Sbjct: 654 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQ-----REQERREQERREQERREQERR 708
Query: 261 DRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVA 320
++ RE+ +Q +R R +E E KA L +Q + E++ + E+ +A
Sbjct: 709 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 768
Query: 321 RIQFR 325
Q +
Sbjct: 769 ERQLQ 773
Score = 53.9 bits (128), Expect = 3e-07
Identities = 55/208 (26%), Positives = 92/208 (44%), Gaps = 24/208 (11%)
Query: 126 QSESSVSTPSASFEPNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSSQEPSG 185
Q + TP+++ P + ++ RN L P S + + + + +E
Sbjct: 500 QRNQMLMTPTSA--PRSVMKSFIKRNTPLRMDPKCSFVEKER----QRLENLRRKEEAEQ 553
Query: 186 CSDQRPAEDLNIRVERLTKKLEER--------------REEKRKEEEQREIKKEIERRKT 231
Q+ ED R+E + K EER +EEK+K+ EQ+ + + + K
Sbjct: 554 LRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKA 613
Query: 232 GKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVE 291
+E L ++ +++ K+M E R K E+ A R R QQ +R + K +EE E
Sbjct: 614 KEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE 673
Query: 292 AAKAAA---LLAKQAEMEVKRESYARER 316
+ AA LA+Q E E +RE RE+
Sbjct: 674 RLRKAAEAKRLAEQREQE-RREQERREQ 700
Score = 48.9 bits (115), Expect = 1e-05
Identities = 34/134 (25%), Positives = 73/134 (54%), Gaps = 9/134 (6%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQREI------KKEIERRKTGKEMLDYKRKQ 242
++ E +R K+L E+RE++R+E+E+RE ++E ERR+ +++ + +R++
Sbjct: 667 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRR 726
Query: 243 EEEL--TKRMLEERNRE-KAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALL 299
E+E +R L+ER + + + + ++++ + +R A +E+ + AK AA
Sbjct: 727 EQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGA 786
Query: 300 AKQAEMEVKRESYA 313
+K + V +S A
Sbjct: 787 SKALNVTVDVQSPA 800
Score = 37.7 bits (86), Expect = 0.025
Identities = 22/90 (24%), Positives = 48/90 (53%), Gaps = 10/90 (11%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEM--------LDYK 239
+Q E ER ++ + +E+R+E+E+ + ++E++ R+ + L+ K
Sbjct: 699 EQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 758
Query: 240 RKQEEE--LTKRMLEERNREKAEDRAARER 267
+K+EE+ L +R L+E +KA++ A +
Sbjct: 759 KKKEEQQRLAERQLQEEQEKKAKEAAGASK 788
Score = 33.9 bits (76), Expect = 0.36
Identities = 32/129 (24%), Positives = 61/129 (47%), Gaps = 23/129 (17%)
Query: 204 KKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQE-EELTKRMLEERNREKAED- 261
K +R R + + ++KE +R + + +RK+E E+L ++ +EE R + E+
Sbjct: 517 KSFIKRNTPLRMDPKCSFVEKERQRLE------NLRRKEEAEQLRRQKVEEDKRRRLEEV 570
Query: 262 -----------RAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRE 310
ARER++Q + + +FA+ E+ E AK L AE + K++
Sbjct: 571 KLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERL----AEEKAKKK 626
Query: 311 SYARERSTV 319
+ A++ V
Sbjct: 627 AAAKKMEEV 635
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 56.6 bits (135), Expect = 5e-08
Identities = 41/185 (22%), Positives = 83/185 (44%), Gaps = 9/185 (4%)
Query: 145 ENSQSRNAELCEIPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTK 204
E + + +I ++ + E A ++++ +R E+ R+ L +
Sbjct: 590 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 649
Query: 205 KLEERREE----KRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAE 260
+ EERR + K+KEEEQ ++K E ++ ++ R+QE +R +ER ++
Sbjct: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQ-----REQERREQERREQERREQERR 704
Query: 261 DRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVA 320
++ RE+ +Q +R R +E E KA L +Q + E++ + E+ +A
Sbjct: 705 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 764
Query: 321 RIQFR 325
Q +
Sbjct: 765 ERQLQ 769
Score = 53.1 bits (126), Expect = 6e-07
Identities = 44/138 (31%), Positives = 73/138 (52%), Gaps = 11/138 (7%)
Query: 189 QRPAEDLNI-RVERLTK------KLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRK 241
+R E++ + R ERL K ++E+ +EEK+K+ EQ+ + + + K +E L ++
Sbjct: 560 RRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKA 619
Query: 242 QEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAA---L 298
+++ K+M E R K E+ A R R QQ +R + K +EE E + AA
Sbjct: 620 KKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR 679
Query: 299 LAKQAEMEVKRESYARER 316
LA+Q E E +RE RE+
Sbjct: 680 LAEQREQE-RREQERREQ 696
Score = 48.9 bits (115), Expect = 1e-05
Identities = 34/134 (25%), Positives = 73/134 (54%), Gaps = 9/134 (6%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQREI------KKEIERRKTGKEMLDYKRKQ 242
++ E +R K+L E+RE++R+E+E+RE ++E ERR+ +++ + +R++
Sbjct: 663 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRR 722
Query: 243 EEEL--TKRMLEERNRE-KAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALL 299
E+E +R L+ER + + + + ++++ + +R A +E+ + AK AA
Sbjct: 723 EQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGA 782
Query: 300 AKQAEMEVKRESYA 313
+K + V +S A
Sbjct: 783 SKALNVTVDVQSPA 796
Score = 48.1 bits (113), Expect = 2e-05
Identities = 36/132 (27%), Positives = 65/132 (49%), Gaps = 3/132 (2%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTK 248
Q+ ED R+E + K EER + + E+ E KE ++++ ++ K E+ +
Sbjct: 553 QKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEE 612
Query: 249 RMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVK 308
R+ EE+ ++KA AA++ + + + E A R ++E E + LL K+ E E +
Sbjct: 613 RLAEEKAKKKA---AAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE 669
Query: 309 RESYARERSTVA 320
R A E +A
Sbjct: 670 RLRKAAEAKRLA 681
Score = 46.2 bits (108), Expect = 7e-05
Identities = 30/112 (26%), Positives = 59/112 (52%), Gaps = 2/112 (1%)
Query: 204 KKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRA 263
+K +R E R++EE +++++ + + + K K+EE L +++L+ R R +
Sbjct: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERL-RKVLQARERVEQMKEE 590
Query: 264 ARERIKQQIA-LDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYAR 314
+++I+Q+ A +D A+ + EE KAAA ++ E K+E AR
Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR 642
Score = 37.7 bits (86), Expect = 0.025
Identities = 22/90 (24%), Positives = 48/90 (53%), Gaps = 10/90 (11%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEM--------LDYK 239
+Q E ER ++ + +E+R+E+E+ + ++E++ R+ + L+ K
Sbjct: 695 EQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 754
Query: 240 RKQEEE--LTKRMLEERNREKAEDRAARER 267
+K+EE+ L +R L+E +KA++ A +
Sbjct: 755 KKKEEQQRLAERQLQEEQEKKAKEAAGASK 784
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 55.8 bits (133), Expect = 9e-08
Identities = 51/184 (27%), Positives = 93/184 (50%), Gaps = 25/184 (13%)
Query: 178 TSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLD 237
+S + S ++ E+ R+ R+ +++E +E KR+EE+++ +KE E R+ EM +
Sbjct: 905 SSEELLSALQKKKQQEEEAERLRRIQEEME--KERKRREEDEKRRRKEEEERRMKLEM-E 961
Query: 238 YKRKQEEELTKRMLEERNREKAE-----DRAARERIKQQIALDRAER----AARFAKTKE 288
KRKQEEE K+ ++ R +AE R E +QQ L++ R A R A+++
Sbjct: 962 AKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEA 1021
Query: 289 EVEAAKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEARQF 348
E+ + +A QA++ ++R R + T ++ + ++F S P A +
Sbjct: 1022 ELISDEA------QADLALRRNDGTRPKMTPEQMAKEM-------SEFLSRGPAVLATKA 1068
Query: 349 AAQT 352
AA T
Sbjct: 1069 AAGT 1072
Score = 34.7 bits (78), Expect = 0.21
Identities = 33/147 (22%), Positives = 63/147 (42%), Gaps = 19/147 (12%)
Query: 193 EDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEEL------ 246
++L I ++ L K++ +E+ Q+E ++ + L K++QEEE
Sbjct: 872 KNLEISIDTLMAKIKSTM--MTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRI 929
Query: 247 -------TKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALL 299
KR E+ R + E+ R +++ + + E + + E+ A+ A L
Sbjct: 930 QEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQL 989
Query: 300 AKQAEMEVKR----ESYARERSTVARI 322
A+Q E E ++ E R+R RI
Sbjct: 990 ARQKEEESQQQAVLEQERRDRELALRI 1016
>gi|10880975 hypothetical protein LOC57821 [Homo sapiens]
Length = 508
Score = 55.8 bits (133), Expect = 9e-08
Identities = 63/238 (26%), Positives = 107/238 (44%), Gaps = 33/238 (13%)
Query: 111 QMHLLKSETSVANGSQSESSVS-----TPSASFEPNNTCENSQSRNAELCEIPPTSDTKS 165
Q L +S S +G++ E S + T S++ EP N + C P+S S
Sbjct: 253 QQLLPRSSNSSVSGTKKEDSTAKIHAVTHSSTGEPLAYIAQPPL-NRKTC---PSSAVNS 308
Query: 166 DTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKE 225
D + G + H T S S + L+ R + L K+LEE+RE+ ++EEE+R+I++E
Sbjct: 309 DRSKGNGKSNHRTQSAHISPVTS---TYCLSPRQKELQKQLEEKREKLKREEERRKIEEE 365
Query: 226 IERRKTG----KEMLDYKRKQEEELTK----RMLEERNREKAEDRAARERI--------- 268
E+++ K L KR+Q E+ + + +E+ N + D R+
Sbjct: 366 KEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQ 425
Query: 269 ---KQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVARIQ 323
+Q L + E F K E E A L K+ E ++++ RER+ R++
Sbjct: 426 MKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQA-VRERTRQLRLE 482
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 55.5 bits (132), Expect = 1e-07
Identities = 37/107 (34%), Positives = 58/107 (54%), Gaps = 13/107 (12%)
Query: 189 QRPAEDLNIRVERLTKKLEERR----EEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEE 244
+R AE+ +R+E +K EE R EEK+K+E + + K E ++ +E L K KQE+
Sbjct: 437 KRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQ 496
Query: 245 ELTKRMLEERNREKAEDRA---------ARERIKQQIALDRAERAAR 282
E ++ + E+ +E AE +A RE+I QI +R ER R
Sbjct: 497 EKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQERLERKKR 543
Score = 53.1 bits (126), Expect = 6e-07
Identities = 46/157 (29%), Positives = 75/157 (47%), Gaps = 18/157 (11%)
Query: 164 KSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIK 223
K A GG++ A + +G +D A + L +K + R +K +EE++R K
Sbjct: 372 KHAAAAGGKAENSAALGKPTAGTTDAGEAAKI------LAEKRRQARLQKEQEEQERVEK 425
Query: 224 KEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARF 283
+E +R E + KRK EEE + LEE R++ E+R +E K++ + +A
Sbjct: 426 EEQDRL----EREELKRKAEEE--RLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEE 479
Query: 284 AKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVA 320
AK K E E LL K+ + + K+E E+ A
Sbjct: 480 AKRKAEEE------LLLKEKQEQEKQEKAMIEKQKEA 510
Score = 37.7 bits (86), Expect = 0.025
Identities = 26/92 (28%), Positives = 46/92 (50%), Gaps = 7/92 (7%)
Query: 200 ERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKA 259
+RL K+ E RE+ EQ+ ++K+ R L Y+ KQ EE +++ E+R RE
Sbjct: 55 QRLAKERREEREKCLAAREQQILEKQKRAR------LQYE-KQMEERWRKLEEQRQREDQ 107
Query: 260 EDRAARERIKQQIALDRAERAARFAKTKEEVE 291
+ A E+ KQ++ + A ++ E +
Sbjct: 108 KRAAVEEKRKQKLREEEERLEAMMRRSLERTQ 139
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 53.9 bits (128), Expect = 3e-07
Identities = 44/162 (27%), Positives = 72/162 (44%), Gaps = 15/162 (9%)
Query: 162 DTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQRE 221
D DT T G + ++ ++ + +R +R ++ + + E +R++EE
Sbjct: 705 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 764
Query: 222 IKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAA 281
++E ER KR++EEEL +R EE R + E A R +++ + E A
Sbjct: 765 RQQEEER----------KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEAL 814
Query: 282 R--FAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVAR 321
R + +EE E K LL KQ E K +ARE R
Sbjct: 815 RRLEERRREEEERRKQEELLRKQEEEAAK---WAREEEEAQR 853
Score = 52.8 bits (125), Expect = 7e-07
Identities = 37/136 (27%), Positives = 71/136 (52%), Gaps = 12/136 (8%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELT 247
+++ E+L + E + ++ +E ++R+EEE K+E R+ ++ + +R++EEE
Sbjct: 748 ERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEER 807
Query: 248 K------RMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAK 301
+ R LEER RE+ E R E +++Q E AA++A+ +EE + L
Sbjct: 808 QQQEEALRRLEERRREEEERRKQEELLRKQ-----EEEAAKWAREEEEAQRRLEENRLRM 862
Query: 302 QAE-MEVKRESYARER 316
+ E ++ E R+R
Sbjct: 863 EEEAARLRHEEEERKR 878
Score = 50.4 bits (119), Expect = 4e-06
Identities = 34/126 (26%), Positives = 66/126 (52%), Gaps = 7/126 (5%)
Query: 198 RVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNRE 257
++++L K + E++R+E E R K+E E RK +E+ R+Q+EE+ +R EE +
Sbjct: 719 QLQQLEKAKAAKLEQERREAEMRA-KREEEERKRQEEL----RRQQEEILRRQQEEERKR 773
Query: 258 KAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERS 317
+ E+ AR + ++ + R + A + +EE + AL ++ E + E R++
Sbjct: 774 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEAL--RRLEERRREEEERRKQE 831
Query: 318 TVARIQ 323
+ R Q
Sbjct: 832 ELLRKQ 837
Score = 48.5 bits (114), Expect = 1e-05
Identities = 36/165 (21%), Positives = 81/165 (49%), Gaps = 9/165 (5%)
Query: 189 QRPAEDLNIRVERLTKKLEERRE---EKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEE 245
+R E+L R + + + +E +++EEE+R+ ++E RR + + +R+++EE
Sbjct: 773 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832
Query: 246 LTKRMLEERNREKAEDRAARERIKQQIALDRAERAARF-----AKTKEEVEAAKAAALLA 300
L ++ EE + E+ A+ R+++ L E AAR + ++E+E + L+
Sbjct: 833 LLRKQEEEAAKWAREEEEAQRRLEEN-RLRMEEEAARLRHEEEERKRKELEVQRQKELMR 891
Query: 301 KQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEA 345
++ + + +++ Q +LP S++ Q + A +A
Sbjct: 892 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQA 936
Score = 40.0 bits (92), Expect = 0.005
Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 10/138 (7%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELT 247
++R E+ + E L +K EE + +EEE+ + + E R + +E + ++EE
Sbjct: 819 ERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR 878
Query: 248 KRMLEERNRE---------KAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAAL 298
K + +R +E +A R +++ +QQ+A + ++ + + A L
Sbjct: 879 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 938
Query: 299 -LAKQAEMEVKRESYARE 315
LA+ ++E +RE RE
Sbjct: 939 SLAEIQKLEEERERQLRE 956
Score = 29.3 bits (64), Expect = 8.8
Identities = 19/73 (26%), Positives = 41/73 (56%), Gaps = 5/73 (6%)
Query: 204 KKLEERREEKRKEE---EQREIKKEIERRKTGKE--MLDYKRKQEEELTKRMLEERNREK 258
+KLEE RE + +EE +QRE+ K +++++ ++ + + + T + L E +E+
Sbjct: 944 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEE 1003
Query: 259 AEDRAARERIKQQ 271
A +++ +QQ
Sbjct: 1004 ARQMQKQQQQQQQ 1016
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 53.9 bits (128), Expect = 3e-07
Identities = 44/162 (27%), Positives = 72/162 (44%), Gaps = 15/162 (9%)
Query: 162 DTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQRE 221
D DT T G + ++ ++ + +R +R ++ + + E +R++EE
Sbjct: 732 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 791
Query: 222 IKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAA 281
++E ER KR++EEEL +R EE R + E A R +++ + E A
Sbjct: 792 RQQEEER----------KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEAL 841
Query: 282 R--FAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVAR 321
R + +EE E K LL KQ E K +ARE R
Sbjct: 842 RRLEERRREEEERRKQEELLRKQEEEAAK---WAREEEEAQR 880
Score = 52.8 bits (125), Expect = 7e-07
Identities = 37/136 (27%), Positives = 71/136 (52%), Gaps = 12/136 (8%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELT 247
+++ E+L + E + ++ +E ++R+EEE K+E R+ ++ + +R++EEE
Sbjct: 775 ERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEER 834
Query: 248 K------RMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAK 301
+ R LEER RE+ E R E +++Q E AA++A+ +EE + L
Sbjct: 835 QQQEEALRRLEERRREEEERRKQEELLRKQ-----EEEAAKWAREEEEAQRRLEENRLRM 889
Query: 302 QAE-MEVKRESYARER 316
+ E ++ E R+R
Sbjct: 890 EEEAARLRHEEEERKR 905
Score = 50.4 bits (119), Expect = 4e-06
Identities = 34/126 (26%), Positives = 66/126 (52%), Gaps = 7/126 (5%)
Query: 198 RVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNRE 257
++++L K + E++R+E E R K+E E RK +E+ R+Q+EE+ +R EE +
Sbjct: 746 QLQQLEKAKAAKLEQERREAEMRA-KREEEERKRQEEL----RRQQEEILRRQQEEERKR 800
Query: 258 KAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERS 317
+ E+ AR + ++ + R + A + +EE + AL ++ E + E R++
Sbjct: 801 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEAL--RRLEERRREEEERRKQE 858
Query: 318 TVARIQ 323
+ R Q
Sbjct: 859 ELLRKQ 864
Score = 48.5 bits (114), Expect = 1e-05
Identities = 36/165 (21%), Positives = 81/165 (49%), Gaps = 9/165 (5%)
Query: 189 QRPAEDLNIRVERLTKKLEERRE---EKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEE 245
+R E+L R + + + +E +++EEE+R+ ++E RR + + +R+++EE
Sbjct: 800 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859
Query: 246 LTKRMLEERNREKAEDRAARERIKQQIALDRAERAARF-----AKTKEEVEAAKAAALLA 300
L ++ EE + E+ A+ R+++ L E AAR + ++E+E + L+
Sbjct: 860 LLRKQEEEAAKWAREEEEAQRRLEEN-RLRMEEEAARLRHEEEERKRKELEVQRQKELMR 918
Query: 301 KQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEA 345
++ + + +++ Q +LP S++ Q + A +A
Sbjct: 919 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQA 963
Score = 40.0 bits (92), Expect = 0.005
Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 10/138 (7%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELT 247
++R E+ + E L +K EE + +EEE+ + + E R + +E + ++EE
Sbjct: 846 ERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR 905
Query: 248 KRMLEERNRE---------KAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAAL 298
K + +R +E +A R +++ +QQ+A + ++ + + A L
Sbjct: 906 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 965
Query: 299 -LAKQAEMEVKRESYARE 315
LA+ ++E +RE RE
Sbjct: 966 SLAEIQKLEEERERQLRE 983
Score = 29.3 bits (64), Expect = 8.8
Identities = 19/73 (26%), Positives = 41/73 (56%), Gaps = 5/73 (6%)
Query: 204 KKLEERREEKRKEE---EQREIKKEIERRKTGKE--MLDYKRKQEEELTKRMLEERNREK 258
+KLEE RE + +EE +QRE+ K +++++ ++ + + + T + L E +E+
Sbjct: 971 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEE 1030
Query: 259 AEDRAARERIKQQ 271
A +++ +QQ
Sbjct: 1031 ARQMQKQQQQQQQ 1043
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 53.9 bits (128), Expect = 3e-07
Identities = 44/162 (27%), Positives = 72/162 (44%), Gaps = 15/162 (9%)
Query: 162 DTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQRE 221
D DT T G + ++ ++ + +R +R ++ + + E +R++EE
Sbjct: 711 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 770
Query: 222 IKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAA 281
++E ER KR++EEEL +R EE R + E A R +++ + E A
Sbjct: 771 RQQEEER----------KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEAL 820
Query: 282 R--FAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVAR 321
R + +EE E K LL KQ E K +ARE R
Sbjct: 821 RRLEERRREEEERRKQEELLRKQEEEAAK---WAREEEEAQR 859
Score = 52.8 bits (125), Expect = 7e-07
Identities = 37/136 (27%), Positives = 71/136 (52%), Gaps = 12/136 (8%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELT 247
+++ E+L + E + ++ +E ++R+EEE K+E R+ ++ + +R++EEE
Sbjct: 754 ERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEER 813
Query: 248 K------RMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAK 301
+ R LEER RE+ E R E +++Q E AA++A+ +EE + L
Sbjct: 814 QQQEEALRRLEERRREEEERRKQEELLRKQ-----EEEAAKWAREEEEAQRRLEENRLRM 868
Query: 302 QAE-MEVKRESYARER 316
+ E ++ E R+R
Sbjct: 869 EEEAARLRHEEEERKR 884
Score = 50.4 bits (119), Expect = 4e-06
Identities = 34/126 (26%), Positives = 66/126 (52%), Gaps = 7/126 (5%)
Query: 198 RVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNRE 257
++++L K + E++R+E E R K+E E RK +E+ R+Q+EE+ +R EE +
Sbjct: 725 QLQQLEKAKAAKLEQERREAEMRA-KREEEERKRQEEL----RRQQEEILRRQQEEERKR 779
Query: 258 KAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERS 317
+ E+ AR + ++ + R + A + +EE + AL ++ E + E R++
Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEAL--RRLEERRREEEERRKQE 837
Query: 318 TVARIQ 323
+ R Q
Sbjct: 838 ELLRKQ 843
Score = 48.5 bits (114), Expect = 1e-05
Identities = 36/165 (21%), Positives = 81/165 (49%), Gaps = 9/165 (5%)
Query: 189 QRPAEDLNIRVERLTKKLEERRE---EKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEE 245
+R E+L R + + + +E +++EEE+R+ ++E RR + + +R+++EE
Sbjct: 779 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
Query: 246 LTKRMLEERNREKAEDRAARERIKQQIALDRAERAARF-----AKTKEEVEAAKAAALLA 300
L ++ EE + E+ A+ R+++ L E AAR + ++E+E + L+
Sbjct: 839 LLRKQEEEAAKWAREEEEAQRRLEEN-RLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897
Query: 301 KQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEA 345
++ + + +++ Q +LP S++ Q + A +A
Sbjct: 898 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQA 942
Score = 40.0 bits (92), Expect = 0.005
Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 10/138 (7%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELT 247
++R E+ + E L +K EE + +EEE+ + + E R + +E + ++EE
Sbjct: 825 ERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR 884
Query: 248 KRMLEERNRE---------KAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAAL 298
K + +R +E +A R +++ +QQ+A + ++ + + A L
Sbjct: 885 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 944
Query: 299 -LAKQAEMEVKRESYARE 315
LA+ ++E +RE RE
Sbjct: 945 SLAEIQKLEEERERQLRE 962
Score = 29.3 bits (64), Expect = 8.8
Identities = 19/73 (26%), Positives = 41/73 (56%), Gaps = 5/73 (6%)
Query: 204 KKLEERREEKRKEE---EQREIKKEIERRKTGKE--MLDYKRKQEEELTKRMLEERNREK 258
+KLEE RE + +EE +QRE+ K +++++ ++ + + + T + L E +E+
Sbjct: 950 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEE 1009
Query: 259 AEDRAARERIKQQ 271
A +++ +QQ
Sbjct: 1010 ARQMQKQQQQQQQ 1022
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 53.9 bits (128), Expect = 3e-07
Identities = 44/162 (27%), Positives = 72/162 (44%), Gaps = 15/162 (9%)
Query: 162 DTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQRE 221
D DT T G + ++ ++ + +R +R ++ + + E +R++EE
Sbjct: 711 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 770
Query: 222 IKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAA 281
++E ER KR++EEEL +R EE R + E A R +++ + E A
Sbjct: 771 RQQEEER----------KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEAL 820
Query: 282 R--FAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVAR 321
R + +EE E K LL KQ E K +ARE R
Sbjct: 821 RRLEERRREEEERRKQEELLRKQEEEAAK---WAREEEEAQR 859
Score = 52.8 bits (125), Expect = 7e-07
Identities = 37/136 (27%), Positives = 71/136 (52%), Gaps = 12/136 (8%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELT 247
+++ E+L + E + ++ +E ++R+EEE K+E R+ ++ + +R++EEE
Sbjct: 754 ERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEER 813
Query: 248 K------RMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAK 301
+ R LEER RE+ E R E +++Q E AA++A+ +EE + L
Sbjct: 814 QQQEEALRRLEERRREEEERRKQEELLRKQ-----EEEAAKWAREEEEAQRRLEENRLRM 868
Query: 302 QAE-MEVKRESYARER 316
+ E ++ E R+R
Sbjct: 869 EEEAARLRHEEEERKR 884
Score = 50.4 bits (119), Expect = 4e-06
Identities = 34/126 (26%), Positives = 66/126 (52%), Gaps = 7/126 (5%)
Query: 198 RVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNRE 257
++++L K + E++R+E E R K+E E RK +E+ R+Q+EE+ +R EE +
Sbjct: 725 QLQQLEKAKAAKLEQERREAEMRA-KREEEERKRQEEL----RRQQEEILRRQQEEERKR 779
Query: 258 KAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERS 317
+ E+ AR + ++ + R + A + +EE + AL ++ E + E R++
Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEAL--RRLEERRREEEERRKQE 837
Query: 318 TVARIQ 323
+ R Q
Sbjct: 838 ELLRKQ 843
Score = 48.5 bits (114), Expect = 1e-05
Identities = 36/165 (21%), Positives = 81/165 (49%), Gaps = 9/165 (5%)
Query: 189 QRPAEDLNIRVERLTKKLEERRE---EKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEE 245
+R E+L R + + + +E +++EEE+R+ ++E RR + + +R+++EE
Sbjct: 779 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
Query: 246 LTKRMLEERNREKAEDRAARERIKQQIALDRAERAARF-----AKTKEEVEAAKAAALLA 300
L ++ EE + E+ A+ R+++ L E AAR + ++E+E + L+
Sbjct: 839 LLRKQEEEAAKWAREEEEAQRRLEEN-RLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897
Query: 301 KQAEMEVKRESYARERSTVARIQFRLPDGSSFTNQFPSDAPLEEA 345
++ + + +++ Q +LP S++ Q + A +A
Sbjct: 898 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQA 942
Score = 40.0 bits (92), Expect = 0.005
Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 10/138 (7%)
Query: 188 DQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELT 247
++R E+ + E L +K EE + +EEE+ + + E R + +E + ++EE
Sbjct: 825 ERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR 884
Query: 248 KRMLEERNRE---------KAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAAL 298
K + +R +E +A R +++ +QQ+A + ++ + + A L
Sbjct: 885 KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATL 944
Query: 299 -LAKQAEMEVKRESYARE 315
LA+ ++E +RE RE
Sbjct: 945 SLAEIQKLEEERERQLRE 962
Score = 29.3 bits (64), Expect = 8.8
Identities = 19/73 (26%), Positives = 41/73 (56%), Gaps = 5/73 (6%)
Query: 204 KKLEERREEKRKEE---EQREIKKEIERRKTGKE--MLDYKRKQEEELTKRMLEERNREK 258
+KLEE RE + +EE +QRE+ K +++++ ++ + + + T + L E +E+
Sbjct: 950 QKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEE 1009
Query: 259 AEDRAARERIKQQ 271
A +++ +QQ
Sbjct: 1010 ARQMQKQQQQQQQ 1022
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 53.9 bits (128), Expect = 3e-07
Identities = 40/121 (33%), Positives = 64/121 (52%), Gaps = 7/121 (5%)
Query: 200 ERLTKKLEER---REEKRKE-EEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERN 255
E+ +K ER RE KRKE E+QR+ ++E ERRK KE +RKQ ++ +ER
Sbjct: 62 EKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERK 121
Query: 256 REKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARE 315
+ E++ RER +++ R ++ + K ++E + K+ E E KRE +E
Sbjct: 122 ERERENKQRRERKRKK---RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKE 178
Query: 316 R 316
R
Sbjct: 179 R 179
Score = 50.1 bits (118), Expect = 5e-06
Identities = 30/97 (30%), Positives = 55/97 (56%), Gaps = 4/97 (4%)
Query: 198 RVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNRE 257
R R KK +ER+E +R+ +++RE K++ R+K ++ +RK+E+E KR + + R+
Sbjct: 109 RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK----ERKREKERGKRERKRKKRK 164
Query: 258 KAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAK 294
K E RER +++ +R + R K + + E K
Sbjct: 165 KEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
Score = 47.8 bits (112), Expect = 2e-05
Identities = 27/116 (23%), Positives = 65/116 (56%), Gaps = 3/116 (2%)
Query: 203 TKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQE---EELTKRMLEERNREKA 259
T++ ER++E+R+ E+++ +++ +R+ GK+ ++K+E E KR E+ R++
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 260 EDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARE 315
++ R+R K++ +R +R R K K+E + + ++ + + +R+ R+
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/118 (28%), Positives = 62/118 (52%), Gaps = 5/118 (4%)
Query: 200 ERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLE-ERNREK 258
ER K+ ++R++ +R +E +R+ K+ ++RK +E KRK+E++ +R R R+K
Sbjct: 57 ERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKK 116
Query: 259 AEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARER 316
++R RER +Q R ER + + K+ + K K+ KR+ RE+
Sbjct: 117 KKERKERERENKQ----RRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK 170
Score = 47.0 bits (110), Expect = 4e-05
Identities = 34/126 (26%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
Query: 198 RVERLTKKLEERREEKRKEEEQ----REIKKEIERRKTGKEMLDYK-RKQEEELTKRMLE 252
R ER K+ +R++EK+K E + RE KK+ ER++ +E + RK+++ K+ +
Sbjct: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
Query: 253 ERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESY 312
ER REK + R+R K++ +R + K+E E + ++ + K++
Sbjct: 146 ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKER 205
Query: 313 ARERST 318
++R T
Sbjct: 206 KKDRKT 211
Score = 46.6 bits (109), Expect = 5e-05
Identities = 37/126 (29%), Positives = 66/126 (52%), Gaps = 5/126 (3%)
Query: 200 ERLTKKLEERREEKRKEE--EQREIKKEIERRKTG-KEMLDYKRKQEEELTKRMLEERNR 256
ER K+ E++R+E+R++E ++++ KK+ ER++ G +E K ++E E + ER R
Sbjct: 76 ERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135
Query: 257 EKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVK-RESYARE 315
+K + R+ K++ + ER R + KEE E + ++ E E K R +E
Sbjct: 136 KKRRKKKRRKERKREKERGKRER-KRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
Query: 316 RSTVAR 321
R R
Sbjct: 195 RKKERR 200
Score = 45.4 bits (106), Expect = 1e-04
Identities = 35/121 (28%), Positives = 61/121 (50%), Gaps = 7/121 (5%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTK 248
QR + + ER ++ E ++ +RK +++R+ KK + RK KE + K+E + K
Sbjct: 108 QRGRRERKKKKERKERERENKQRRERKRKKRRK-KKRRKERKREKE----RGKRERKRKK 162
Query: 249 RMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVK 308
R EE REK +R +ER K++ +R ER K + + + K +Q + +V
Sbjct: 163 RKKEE--REKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVF 220
Query: 309 R 309
R
Sbjct: 221 R 221
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/98 (27%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Query: 185 GCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEE 244
G +++ ++ R ++ E +R+++RK++ ++E K+E ER K +E KRK+EE
Sbjct: 110 GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGK--RERKRKKRKKEE 167
Query: 245 ELTKRMLEERNREKAEDRAARERIKQQIALDRAERAAR 282
KR + R+K +R R K++ +R ++ R
Sbjct: 168 REKKRERNRKERKKERERKERRERKKERKKERRKKKER 205
Score = 43.9 bits (102), Expect = 3e-04
Identities = 36/121 (29%), Positives = 64/121 (52%), Gaps = 13/121 (10%)
Query: 204 KKLEERREEKRK---EEEQ-----REIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERN 255
+K E R EKRK E+E+ ++ KK+ ++R+ GKE + KRK+ E+ K E+
Sbjct: 36 RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKER-ERKRKEREKQRKERREKER 94
Query: 256 REKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARE 315
R++ +++ RER KQ+ R ER + + + E E + K+ + +R+ RE
Sbjct: 95 RKRKKEKKKRER-KQR---GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Query: 316 R 316
+
Sbjct: 151 K 151
Score = 42.7 bits (99), Expect = 8e-04
Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 14/125 (11%)
Query: 197 IRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNR 256
+ ++K +R E++KE +RE K++ ER K K + + ++E KR ER +
Sbjct: 20 VSCSHISKPCTQRESERKKERRERE-KRKREREKERK-----RERGKKEKKKRKKRERGK 73
Query: 257 EKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARER 316
E+ R RE+ ++ +R E+ R K + E K + E + K+E RER
Sbjct: 74 ERERKRKEREKQRK----ERREKERR----KRKKEKKKRERKQRGRRERKKKKERKERER 125
Query: 317 STVAR 321
R
Sbjct: 126 ENKQR 130
Score = 42.7 bits (99), Expect = 8e-04
Identities = 26/108 (24%), Positives = 52/108 (48%)
Query: 209 RREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERI 268
+RE +RK+E + K++ ER K K K K++ + +R E + K ++ +ER
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 269 KQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARER 316
+++ + E+ R K + E K ++ E + +RE ++R
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 53.5 bits (127), Expect = 4e-07
Identities = 32/96 (33%), Positives = 53/96 (55%), Gaps = 5/96 (5%)
Query: 189 QRPAEDLNIRVERLTKKLEERR-----EEKRKEEEQREIKKEIERRKTGKEMLDYKRKQE 243
+R E+ ER +K ER+ EE+RKE+E++E KK RK K+ + K ++E
Sbjct: 148 ERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207
Query: 244 EELTKRMLEERNREKAEDRAARERIKQQIALDRAER 279
+ ++ EER +E+ +DR R K++ +R ER
Sbjct: 208 RKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
Score = 52.8 bits (125), Expect = 7e-07
Identities = 38/137 (27%), Positives = 72/137 (52%), Gaps = 4/137 (2%)
Query: 182 EPSGCSDQRPAE-DLNIRVERLTKKLEERREEKR-KEEEQREIKKEIERRKTGKEMLDYK 239
+P S+ R E ++ R E ++ ER++E+R +E+ +RE +KE +R + KE +
Sbjct: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90
Query: 240 RKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALL 299
+K+E E KR E+ N+E E +++ K++ R + + + KEE + +
Sbjct: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKKE--RGRTSKEGKERERKEERKREERKERE 148
Query: 300 AKQAEMEVKRESYARER 316
K+ E E +RE R++
Sbjct: 149 RKKEEREKERERKERKK 165
Score = 48.9 bits (115), Expect = 1e-05
Identities = 38/118 (32%), Positives = 60/118 (50%), Gaps = 7/118 (5%)
Query: 200 ERLTKKLEERREEKRKEEEQREIKKEI-ERRKTGKEMLDYKRKQEEELTKRMLEERNREK 258
ER KK +E K EE+++ KKE ER +T KE + +RK+E + +R +ER R+K
Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER--KERERKK 151
Query: 259 AEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARER 316
E RER +++ + ER K +E E + ++ E K+E +ER
Sbjct: 152 EEREKERERKERK----KRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER 205
Score = 48.1 bits (113), Expect = 2e-05
Identities = 32/127 (25%), Positives = 64/127 (50%), Gaps = 6/127 (4%)
Query: 190 RPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKR 249
R +++ R + +K EER+E +RK+EE+ + ++ ER+K ++ + K ++ +E
Sbjct: 125 RTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE---- 180
Query: 250 MLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKR 309
+ER K +R +ER K++ +R ER K +E + + + + KR
Sbjct: 181 --KERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKR 238
Query: 310 ESYARER 316
E R++
Sbjct: 239 ERKERKK 245
Score = 46.6 bits (109), Expect = 5e-05
Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 19/145 (13%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKR----------KEEEQREIKKEIERR--KTGKEML 236
+R +E R ER +K E +E KR +++E+RE KK + K G+E
Sbjct: 54 ERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKE 113
Query: 237 DYKRKQEEELTKRMLEERNRE-----KAEDRAARERIKQQIALDRAERAARFAKTKEEVE 291
K+K+++E + E + RE K E+R RER K++ +R ER R + +++V
Sbjct: 114 KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER-ERKERKKRERKQV- 171
Query: 292 AAKAAALLAKQAEMEVKRESYARER 316
K K+ + KRE +ER
Sbjct: 172 GEKEEERKEKERKERKKRERNRKER 196
Score = 46.2 bits (108), Expect = 7e-05
Identities = 36/115 (31%), Positives = 58/115 (50%), Gaps = 5/115 (4%)
Query: 204 KKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNRE--KAED 261
KK E R+++R+E+E +E +++ +R+K KE + R +E + EER RE K +
Sbjct: 91 KKEERERKKRRREKENKEGEEKEKRKK--KEKKERGRTSKEGKERERKEERKREERKERE 148
Query: 262 RAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARER 316
R ER K++ +R +R + KEE E + K+ E K RER
Sbjct: 149 RKKEEREKERERKERKKRERKQVGEKEE-ERKEKERKERKKRERNRKERKKERER 202
Score = 45.1 bits (105), Expect = 2e-04
Identities = 36/149 (24%), Positives = 73/149 (48%), Gaps = 5/149 (3%)
Query: 181 QEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQR----EIKKEIERRKTGKEML 236
+E G + E R E+ K+ EE+ + K+KE+++R + KE ER++ K
Sbjct: 84 KEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143
Query: 237 DYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAA 296
+R++++E ++ E + R+K E + E+ +++ +R ER R KE + +
Sbjct: 144 RKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERK 203
Query: 297 ALLAKQAEMEVKRESYARERSTVARIQFR 325
++ E + K+E +ER + +R
Sbjct: 204 ERRERKKERK-KKEERKKERQKDRQTNWR 231
Score = 41.6 bits (96), Expect = 0.002
Identities = 33/118 (27%), Positives = 57/118 (48%), Gaps = 4/118 (3%)
Query: 208 ERREEKRKEEEQREIKKE--IERRKTGKEMLDYKRKQEEELTKRM--LEERNREKAEDRA 263
E RE +R+ E ++E KKE ER+K +E KR++E+E + E++ K E+R
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
Query: 264 ARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVAR 321
++R +++ + E+ R K K+E ++ E + E RER R
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 53.1 bits (126), Expect = 6e-07
Identities = 50/198 (25%), Positives = 88/198 (44%), Gaps = 32/198 (16%)
Query: 162 DTKSDTATGGESAGHA------TSSQEPSGCSDQRPAEDLNIRVE-----RLTKKLEERR 210
D+K D+ GE H S + R ED ++ ++ +K+ R+
Sbjct: 42 DSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRK 101
Query: 211 EEKRKEEEQREIK---KEIERRKTGKEMLDYKRKQEEELTKR------------MLEERN 255
+EKRKE++ +K +E ERRK +E D R++ E +R LE+
Sbjct: 102 DEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLE 161
Query: 256 REKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAA----LLAKQAEMEVKRES 311
R++ +R RE+ K+Q ++ ER R + ++E EA + + + + +VK
Sbjct: 162 RKRERERKMREQQKEQ--REQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASH 219
Query: 312 YARERSTVARIQFRLPDG 329
++R R +F L DG
Sbjct: 220 WSRSPPRPPRERFELGDG 237
Score = 35.8 bits (81), Expect = 0.095
Identities = 39/130 (30%), Positives = 58/130 (44%), Gaps = 18/130 (13%)
Query: 204 KKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEE---------ELTKRMLEER 254
K L+E +EK++ +EQ E K EI+R K + D KR E E+T R R
Sbjct: 11 KTLDEILQEKKRRKEQEE-KAEIKRLKNSDDR-DSKRDSLEEGELRDHCMEITIRNSPYR 68
Query: 255 NREKAEDRAARERIKQQIALDRAERAARFAKT---KEEVEAAKAAALLAKQAEMEVKRES 311
+ EDR + +A+ ++ +R K K+E K A + K+ E E +R
Sbjct: 69 REDSMEDRGEED---DSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARV-KEKEREHERRK 124
Query: 312 YARERSTVAR 321
RE AR
Sbjct: 125 RHREEQDKAR 134
Score = 34.7 bits (78), Expect = 0.21
Identities = 26/121 (21%), Positives = 56/121 (46%), Gaps = 11/121 (9%)
Query: 154 LCEIPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEK 213
L ++ SD++ T S+ ++S++ SG ++ E+ +++ EE EE+
Sbjct: 252 LSDLQDISDSERKT-----SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEE 306
Query: 214 RKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKR-----MLEER-NREKAEDRAARER 267
+EEE+ E ++ +E+ + + ++EE + E R +R+ E A E
Sbjct: 307 EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 366
Query: 268 I 268
+
Sbjct: 367 V 367
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 52.8 bits (125), Expect = 7e-07
Identities = 40/132 (30%), Positives = 68/132 (51%), Gaps = 7/132 (5%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTK 248
QR E R + ++ E RE +R+ E +R+ +KE ER++ + +D +R ++
Sbjct: 304 QRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG 363
Query: 249 RMLEERNREKAEDR---AARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEM 305
R ER RE+ +R +ARER +++ DR + R +T+++ + + KQ E
Sbjct: 364 RRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRET---EKQRER 420
Query: 306 EVKRES-YARER 316
E RES RER
Sbjct: 421 EKDRESERGRER 432
Score = 45.1 bits (105), Expect = 2e-04
Identities = 32/118 (27%), Positives = 59/118 (50%), Gaps = 8/118 (6%)
Query: 200 ERLTKKLEERREEKRKE-EEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREK 258
ER T + +RR E+ +E E +RE ++E ER + + +R++E E ++ ER+REK
Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREK 339
Query: 259 AEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARER 316
+R + K+Q +DR + + + E + ++ + + RE RER
Sbjct: 340 ERER----KRKRQTEMDRERNRQTGREGRRQAERERER---ERERDRQSAREREERER 390
Score = 43.9 bits (102), Expect = 3e-04
Identities = 37/113 (32%), Positives = 54/113 (47%), Gaps = 6/113 (5%)
Query: 205 KLEERREEK-RKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRA 263
K E+R E+ R+ E +RE + E ER++ D +RK E E K+ ER E+ +R
Sbjct: 200 KTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER- 258
Query: 264 ARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARER 316
+ER +++ DR R K +E K + E E KRE RER
Sbjct: 259 DKERERER---DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRER-QRER 307
Score = 43.5 bits (101), Expect = 5e-04
Identities = 37/127 (29%), Positives = 63/127 (49%), Gaps = 11/127 (8%)
Query: 162 DTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEE--- 218
D + + TG E A +E D++ A + R ER + +R++E+ ++ E
Sbjct: 352 DRERNRQTGREGRRQAERERERERERDRQSARE---REERERDRDRDRQKERERQTEKDR 408
Query: 219 --QREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDR-AARERIKQQIALD 275
QRE +K+ ER K + +R +E E K+ ER+RE+ DR A R+R + + ++
Sbjct: 409 DGQRETEKQREREKDRESERGRERGRERE--KQKGRERDRERQTDRQAGRQRKRSTLYVN 466
Query: 276 RAERAAR 282
R AR
Sbjct: 467 PPPRTAR 473
Score = 42.0 bits (97), Expect = 0.001
Identities = 29/120 (24%), Positives = 58/120 (48%), Gaps = 6/120 (5%)
Query: 200 ERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKA 259
ER ++ +R ++R++E +R+ ++ +RR + KR+++ E + R RE+
Sbjct: 261 ERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERE 320
Query: 260 EDRAARERIKQQIALDRAERAARFAKTKEEVEAAK---AAALLAKQAEMEVKRESYARER 316
+R +++ DR + R K + E++ + +QAE E +RE RER
Sbjct: 321 RERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE---RER 377
Score = 41.6 bits (96), Expect = 0.002
Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 200 ERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKA 259
ER +K ERR EKR+ E + + K+E R K D RK++ ++ E+ RE+
Sbjct: 55 ERNRQKERERRREKRQTERETDRKRERRREK------DRHRKRDRHRERQRDREKERERQ 108
Query: 260 EDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERST 318
DR R+R +++ +R + R +T+ E E + ++ + RER T
Sbjct: 109 TDR-ERDRQREK---ERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT 163
Score = 40.8 bits (94), Expect = 0.003
Identities = 31/114 (27%), Positives = 57/114 (50%), Gaps = 11/114 (9%)
Query: 204 KKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRA 263
++ E E KR+ + +R+ +++ ER + + + ++E E K ER+R++ DR
Sbjct: 216 RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRR 275
Query: 264 ARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRE-SYARER 316
+ER ++Q R R R +T+ + E +Q E E +RE + RER
Sbjct: 276 QKER-ERQTDRKRQRRTERDRETERKRE---------RQRERERERERNRKRER 319
Score = 40.4 bits (93), Expect = 0.004
Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 6/147 (4%)
Query: 175 GHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKE 234
G A + R E R +R T++ +R+ E+R+E++ R K++ R +
Sbjct: 43 GQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD-RHRKRDRHRERQRDR 101
Query: 235 MLDYKRKQEEELTKRMLEERNREKAEDR-----AARERIKQQIALDRAERAARFAKTKEE 289
+ +R+ + E ++ +ERNR+K +R R R +Q ER K +E
Sbjct: 102 EKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER 161
Query: 290 VEAAKAAALLAKQAEMEVKRESYARER 316
+ + + E +RE +ER
Sbjct: 162 QTDRERQRQTERNRQKEREREKNRQER 188
Score = 38.9 bits (89), Expect = 0.011
Identities = 34/150 (22%), Positives = 66/150 (44%), Gaps = 20/150 (13%)
Query: 172 ESAGHATSSQEPSGCSDQRPAEDLNIRVERLT-----KKLEERREEKRKEEEQREIKKEI 226
E G ++ G ++ D ER T ++ E R+++R+ E+ R+ ++E
Sbjct: 132 EREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRER 191
Query: 227 ERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKT 286
ER ++++E T+ ER RE+ +R +++ DR R +
Sbjct: 192 ER-----------QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTER 240
Query: 287 KEEVEAAKAAALLAKQAEMEVKRESYARER 316
+ E +A + A ++ E + +RE RER
Sbjct: 241 EREKQAERERA-SERETERDKERE---RER 266
Score = 38.9 bits (89), Expect = 0.011
Identities = 37/158 (23%), Positives = 67/158 (42%), Gaps = 11/158 (6%)
Query: 160 TSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEER-----REEKR 214
T D S+ E + E +D+ D + ER +K ER RE +R
Sbjct: 201 TEDRHSERGRERERERETETETERKRQTDRE--RDRQRKTEREREKQAERERASERETER 258
Query: 215 KEEEQREIKKEIERRKTGKE---MLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQ 271
+E +RE ++ +R + KE D KR++ E + +R R++ +R K++
Sbjct: 259 DKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRE 318
Query: 272 IALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKR 309
+R R +T+ + E + +Q EM+ +R
Sbjct: 319 RERERERERERQRETERDREKERERK-RKRQTEMDRER 355
Score = 38.1 bits (87), Expect = 0.019
Identities = 37/127 (29%), Positives = 66/127 (51%), Gaps = 12/127 (9%)
Query: 200 ERLTKKLEERREEK---RKEEEQREIKKEIER---RKT-GKEMLDYKRKQEEELTKRMLE 252
ER T + +R+ EK R++E +RE ++E ER R+T G+ + +R E+E ++
Sbjct: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDR 165
Query: 253 ERNREKAEDRAARERIKQQIALDRAER-AARFAKTKEEVEAAKAAALLAKQAEMEVKRES 311
ER R+ +R +ER +++ +R ER R + K E ++ ++ E E + E
Sbjct: 166 ERQRQTERNR-QKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETE- 223
Query: 312 YARERST 318
R+R T
Sbjct: 224 --RKRQT 228
Score = 37.7 bits (86), Expect = 0.025
Identities = 26/109 (23%), Positives = 54/109 (49%), Gaps = 2/109 (1%)
Query: 204 KKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTK-RMLEERNREKAEDR 262
++ + R+ +RK E +RE + E ER + D +R++E + + R ++ RE+ DR
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDR 285
Query: 263 AARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRES 311
+ R ++ +R +R + + +E K ++ E E +RE+
Sbjct: 286 KRQRRTERDRETER-KRERQRERERERERNRKRERERERERERERQRET 333
Score = 36.2 bits (82), Expect = 0.072
Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 5/116 (4%)
Query: 200 ERLTKKLEERREEKRKEEE---QREIK--KEIERRKTGKEMLDYKRKQEEELTKRMLEER 254
ER ++ ER EK+ E E +RE + KE ER + D ++K+ E T R + R
Sbjct: 231 ERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRR 290
Query: 255 NREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRE 310
E RER +++ R + +E + ++ E E KR+
Sbjct: 291 TERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRK 346
Score = 35.8 bits (81), Expect = 0.095
Identities = 31/136 (22%), Positives = 61/136 (44%), Gaps = 15/136 (11%)
Query: 198 RVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNRE 257
R + ++ E RE +R+ E R+ + + +R + + + +R+++ + ++ ERNR+
Sbjct: 117 REKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQ 176
Query: 258 KAEDR---------AARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLA-----KQA 303
K +R R+R K+ DR R + + E E +Q
Sbjct: 177 KEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQR 236
Query: 304 EMEVKRESYA-RERST 318
+ E +RE A RER++
Sbjct: 237 KTEREREKQAERERAS 252
Score = 33.1 bits (74), Expect = 0.61
Identities = 27/133 (20%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIER-RKTGKEMLDYKRKQEEELT 247
+R E R + +++ R + E +R+ ++E ER R+ ++ + ++E +
Sbjct: 334 ERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRD 393
Query: 248 KRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEV 307
+ +ER R+ +DR + ++Q ++ + R + E E K + E +
Sbjct: 394 RDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGR---ERDRERQT 450
Query: 308 KRES-YARERSTV 319
R++ R+RST+
Sbjct: 451 DRQAGRQRKRSTL 463
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 52.8 bits (125), Expect = 7e-07
Identities = 50/198 (25%), Positives = 88/198 (44%), Gaps = 32/198 (16%)
Query: 162 DTKSDTATGGESAGHA------TSSQEPSGCSDQRPAEDLNIRVE-----RLTKKLEERR 210
D+K D+ GE H S + R ED ++ ++ +K+ R+
Sbjct: 8 DSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRK 67
Query: 211 EEKRKEEEQREIK---KEIERRKTGKEMLDYKRKQEEELTKR------------MLEERN 255
+EKRKE++ +K +E ERRK +E D R++ E +R LE+
Sbjct: 68 DEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLE 127
Query: 256 REKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAAKAAA----LLAKQAEMEVKRES 311
R++ +R RE+ K+Q ++ ER R + ++E EA + + + + +VK
Sbjct: 128 RKRERERKMREQQKEQ--REQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASH 185
Query: 312 YARERSTVARIQFRLPDG 329
++R R +F L DG
Sbjct: 186 WSRSPPRPPRERFELGDG 203
Score = 34.7 bits (78), Expect = 0.21
Identities = 26/121 (21%), Positives = 56/121 (46%), Gaps = 11/121 (9%)
Query: 154 LCEIPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEK 213
L ++ SD++ T S+ ++S++ SG ++ E+ +++ EE EE+
Sbjct: 218 LSDLQDISDSERKT-----SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEE 272
Query: 214 RKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKR-----MLEER-NREKAEDRAARER 267
+EEE+ E ++ +E+ + + ++EE + E R +R+ E A E
Sbjct: 273 EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 332
Query: 268 I 268
+
Sbjct: 333 V 333
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 52.0 bits (123), Expect = 1e-06
Identities = 40/140 (28%), Positives = 69/140 (49%), Gaps = 14/140 (10%)
Query: 200 ERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNRE-- 257
++L + ++R E+KR+E+E E ++ ER++ E L+ +RK+EE+L KR ++R+RE
Sbjct: 276 QKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELR 335
Query: 258 ----KAEDRAARERIKQQIALDRAERAARFAKTK--------EEVEAAKAAALLAKQAEM 305
K E A E+ + Q + ER A+ E + AKA L ++ +
Sbjct: 336 RNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKE 395
Query: 306 EVKRESYARERSTVARIQFR 325
E R ER + + R
Sbjct: 396 EKLRLQQQEERRRLQEAELR 415
Score = 35.4 bits (80), Expect = 0.12
Identities = 34/144 (23%), Positives = 66/144 (45%), Gaps = 24/144 (16%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEE---------QREIKKEIER--RKTGKEMLD 237
++ AE+ ER K+LEE E+++EE+ RE+++ ++ + +E
Sbjct: 292 EKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQ 351
Query: 238 YKRKQEEELTKRMLEERN------------REKAEDRAARERIKQQIALDRAERAARFAK 285
+ K + E K +L +RN R KA +E+ ++++ L + E R +
Sbjct: 352 LQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQE 411
Query: 286 TK-EEVEAAKAAALLAKQAEMEVK 308
+ VE K AL ++ E E++
Sbjct: 412 AELRRVEEEKERALGLQRKERELR 435
Score = 30.4 bits (67), Expect = 4.0
Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 14/83 (16%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTK 248
QR + + + E L++ + E+ ++EE+ ++++ ERR R QE EL +
Sbjct: 367 QRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERR----------RLQEAEL-R 415
Query: 249 RMLEERNRE---KAEDRAARERI 268
R+ EE+ R + ++R RER+
Sbjct: 416 RVEEEKERALGLQRKERELRERL 438
Score = 30.0 bits (66), Expect = 5.2
Identities = 20/79 (25%), Positives = 45/79 (56%), Gaps = 4/79 (5%)
Query: 194 DLNIRVERLTKKLEERREEK---RKEEEQREIKK-EIERRKTGKEMLDYKRKQEEELTKR 249
+L R + + + +E++EEK +++EE+R +++ E+ R + KE +++E EL +R
Sbjct: 378 ELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRER 437
Query: 250 MLEERNREKAEDRAARERI 268
+L +K +D + +
Sbjct: 438 LLSILLSKKPDDSHTHDEL 456
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 52.0 bits (123), Expect = 1e-06
Identities = 52/205 (25%), Positives = 91/205 (44%), Gaps = 25/205 (12%)
Query: 118 ETSVANGSQSESSVSTPSASFEPNNTCENSQSRNAELCEIPPTSDTKSDTATGGESAGHA 177
E +V + +E V + + P + + +P + + ++T SA
Sbjct: 409 EATVEERTPAEPEVGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVSAPSSTVNASASVK 468
Query: 178 TSSQEPSGCSDQRPAEDLNIRVERLTKKLEERRE-EKRKEEEQREIKKEIERRKTGKEML 236
TS+ G +D A L RL ++ E+ E E+R++EE K+E ++ +E
Sbjct: 469 TSA----GTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEE-- 522
Query: 237 DYKRKQEEELTKRMLEERNREK-------AEDRAARERIKQQIALDRAERAARFAKTKEE 289
+ + EE ++R+ E+ REK AE+RA RER + AERA R + +EE
Sbjct: 523 --RTTRREEESRRLEAEQAREKEEQLQRQAEERALRER-------EEAERAQR--QKEEE 571
Query: 290 VEAAKAAALLAKQAEMEVKRESYAR 314
+ A + ++ E +RE R
Sbjct: 572 ARVREEAERVRQEREKHFQREEQER 596
Score = 47.0 bits (110), Expect = 4e-05
Identities = 38/139 (27%), Positives = 61/139 (43%), Gaps = 5/139 (3%)
Query: 156 EIPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRK 215
E P S D A S Q + S +P +RV+ + ERREE+ K
Sbjct: 21 ETAPDSYKVQDKKNASSRPASAISGQN-NNHSGNKPDPPPVLRVDDRQRLARERREEREK 79
Query: 216 EEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALD 275
+ REI +ER + ++ + K EE KR+ E+R +E+ A E+ +Q++ D
Sbjct: 80 QLAAREIVW-LEREERARQ---HYEKHLEERKKRLEEQRQKEERRRAAVEEKRRQRLEED 135
Query: 276 RAERAARFAKTKEEVEAAK 294
+ A +T E + K
Sbjct: 136 KERHEAVVRRTMERSQKPK 154
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/104 (31%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTK 248
QR AE+ R E +++LE E+ R++EEQ + + E + +E +R++EEE
Sbjct: 517 QRVAEERTTRREEESRRLEA--EQAREKEEQLQRQAEERALREREEAERAQRQKEEEARV 574
Query: 249 RMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEEVEA 292
R ER R++ E RE +Q L+R +R K EA
Sbjct: 575 REEAERVRQEREKHFQRE---EQERLERKKRLEEIMKRTRRTEA 615
Score = 38.5 bits (88), Expect = 0.015
Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 224 KEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARF 283
+E R K L +++++EE +R EE R+K RE + Q++A +R R
Sbjct: 477 EEATRLLAEKRRLAREQREKEERERREQEELERQK------REELAQRVAEERTTRREEE 530
Query: 284 AKTKEEVEAAKAAALLAKQAEMEVKRESYARERS 317
++ E +A + L +QAE RE ER+
Sbjct: 531 SRRLEAEQAREKEEQLQRQAEERALREREEAERA 564
Score = 36.2 bits (82), Expect = 0.072
Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 10/89 (11%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTK 248
QR AE ER ++ EE +R++EE+ +++E ER + +E + +QE K
Sbjct: 547 QRQAE------ERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERK 600
Query: 249 RMLEE----RNREKAEDRAARERIKQQIA 273
+ LEE R +A D+ ++ IA
Sbjct: 601 KRLEEIMKRTRRTEATDKKTSDQRNGDIA 629
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 51.6 bits (122), Expect = 2e-06
Identities = 42/147 (28%), Positives = 75/147 (51%), Gaps = 10/147 (6%)
Query: 158 PPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEE 217
PP D D +T + + +E + ++ P E I E+ ++ EE EE+ +EE
Sbjct: 311 PPWEDAHQDVSTSPQGTEVVPAYEEENKAVEKMPRELSRIEEEKEDEEEEEEEEEEEEEE 370
Query: 218 EQREIKKE---IERRKTGKEMLDYKRKQ---EEELTKRMLEERNREKAEDRAARERIKQQ 271
E E+ + + + G+ D R Q +++L + + EE +E AE++A E ++
Sbjct: 371 EVTEVLLDSCVVSQVGVGQSEEDGTRPQSTSDQKLWEEVGEEAKKE-AEEKAKEE--AEE 427
Query: 272 IALDRAERAAR-FAKTKEEVEAAKAAA 297
+A + AE+ + +A+TKEE EA AA
Sbjct: 428 VAEEEAEKEPQDWAETKEEPEAEAEAA 454
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 51.6 bits (122), Expect = 2e-06
Identities = 66/305 (21%), Positives = 128/305 (41%), Gaps = 46/305 (15%)
Query: 118 ETSVANGSQSESSVSTPSASFEPNNTCENSQSRNAEL-CEIPPTSDTKSDTATGGESAGH 176
E ++ Q E + ASFE + + AEL E+ DT E A
Sbjct: 1914 EDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGRIRSNAEDTLRSKEQAEL 1967
Query: 177 ATSSQEPSGCSDQRPAEDLNIRVER-LTKKLEERREEKRKEEEQREIKKEIERRKTGKEM 235
+ Q ++R + RV++ L + E R+ K EE +K ++E + +E
Sbjct: 1968 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2027
Query: 236 LDYKRKQEEELTKRMLEERNR--EKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAA 293
+ + ++ +L + ++R + EKA A +++ +Q++ + + + + E EAA
Sbjct: 2028 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQK-EQELQQTLQQEQSVLDQLRGEAEAA 2086
Query: 294 KAAALLAKQAEMEVKRES--------------YARERSTVARIQFRL------------- 326
+ AA A++A ++ +RE+ + E AR Q +
Sbjct: 2087 RRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2146
Query: 327 -----PDGSSFTNQFPSDAPLEEARQFAAQTV-GNTYGNFSLATMFPRREFTKEDYKKKL 380
+ ++ + +DA +E+ ++FA QT+ L T+ R + + D++K L
Sbjct: 2147 ARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTL--RLQLEETDHQKNL 2204
Query: 381 LDLEL 385
LD EL
Sbjct: 2205 LDEEL 2209
Score = 46.2 bits (108), Expect = 7e-05
Identities = 31/116 (26%), Positives = 61/116 (52%), Gaps = 3/116 (2%)
Query: 209 RREEKRKEEEQREIKKEIER-RKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARER 267
R + E ++R+ ++E ER R+ ++ KR+ E EL R+ E + + RA +
Sbjct: 1479 RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQAL 1538
Query: 268 IKQQIALDRAERAARFAKTK--EEVEAAKAAALLAKQAEMEVKRESYARERSTVAR 321
+ ++ + AER R A+ + +V+ A A + +AE++ KR S+A + + + R
Sbjct: 1539 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1594
Score = 40.8 bits (94), Expect = 0.003
Identities = 38/154 (24%), Positives = 71/154 (46%), Gaps = 25/154 (16%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQRE-IKKEIER-----------RKTGKEML 236
+R ++ ++ V +L ++ E R +++ + E RE ++E+ER R +E+
Sbjct: 1593 ERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1652
Query: 237 DYK-------RKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEE 289
K KQ+EE + E R R KAE++A R+R ++A E+ + A+ +
Sbjct: 1653 QQKSLAQAEAEKQKEEAER---EARRRGKAEEQAVRQR---ELAEQELEKQRQLAEGTAQ 1706
Query: 290 VEAAKAAALLAKQAEMEVKRESYARERSTVARIQ 323
A L+ +AE E + +AR+Q
Sbjct: 1707 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1740
Score = 40.4 bits (93), Expect = 0.004
Identities = 49/257 (19%), Positives = 104/257 (40%), Gaps = 8/257 (3%)
Query: 97 VSADELVTRIHKVRQMHLLKSETSVANGSQS-ESSVSTPSASF-EPNNTCENS-QSRNAE 153
+ A+E R+ + + + ++ +S E+ + + ASF E E S Q +
Sbjct: 1543 LQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1602
Query: 154 LCEIPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLT--KKLEERRE 211
+ ++ ++ ++ E A + A L ++ E + K L +
Sbjct: 1603 VAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEA 1662
Query: 212 EKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQ 271
EK+KEE +RE ++ R K ++ + + E+EL K+ + A +E I+ +
Sbjct: 1663 EKQKEEAEREARR---RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1719
Query: 272 IALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSS 331
++ E+ + + + +AAA K+ E+E + E + + R + S
Sbjct: 1720 AETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESR 1779
Query: 332 FTNQFPSDAPLEEARQF 348
T++ EA +F
Sbjct: 1780 STSEKSKQRLEAEAGRF 1796
Score = 40.4 bits (93), Expect = 0.004
Identities = 27/92 (29%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Query: 207 EERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRA-AR 265
++R++++ ++E QR + E R+ E + R+++EEL + LE++ R++ E A
Sbjct: 2534 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL--QQLEQQRRQQEELLAEEN 2591
Query: 266 ERIKQQIALDRAERAARFAKTKEEVEAAKAAA 297
+R+++Q+ L + A A + EEV A++ AA
Sbjct: 2592 QRLREQLQLLEEQHRAALAHS-EEVTASQVAA 2622
Score = 37.4 bits (85), Expect = 0.032
Identities = 44/233 (18%), Positives = 93/233 (39%), Gaps = 22/233 (9%)
Query: 99 ADELVTRIHKVRQMHLLKSETSVANGSQSESSVSTPSASFEPNNTCE-NSQSRNAELCE- 156
A+ + + Q +++ E + + Q + S+ ++ E +++R AE E
Sbjct: 1386 AEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER 1445
Query: 157 -----------IPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKK 205
+ + G E A ++ + +R A++ ERL ++
Sbjct: 1446 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE---EAERLRRQ 1502
Query: 206 LEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAAR 265
+++ + KR+ E + R K E K++ + L + L+ E+ +A
Sbjct: 1503 VQDESQRKRQAEVEL-----ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEV 1557
Query: 266 ERIKQ-QIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERS 317
ER +Q Q+AL+ A+R+A + A+ A L + + E + RE +
Sbjct: 1558 ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1610
Score = 37.0 bits (84), Expect = 0.042
Identities = 40/149 (26%), Positives = 70/149 (46%), Gaps = 15/149 (10%)
Query: 177 ATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEML 236
A +E + + +R ++L + ++ ++E K + EE+ E +++ E
Sbjct: 1737 ARLQREAAAATQKR--QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAG 1794
Query: 237 DYKRKQEEELTKRMLEE---RNREKAEDRAARERIKQQIALDRAERAARFAK-TKEEVEA 292
++ EE R L E R R+ AE+ AAR+R + + L AE+ A + T+ + EA
Sbjct: 1795 RFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVL--AEKLAAIGEATRLKTEA 1852
Query: 293 AKAAALLAKQAEMEVKR-----ESYARER 316
AL K+AE E R E++ R R
Sbjct: 1853 --EIALKEKEAENERLRRLAEDEAFQRRR 1879
Score = 35.0 bits (79), Expect = 0.16
Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 11/128 (8%)
Query: 200 ERLTKKLEERREEKRKEEEQREIKKEIE-----RRKTGKEMLDYKRKQE---EELTKRML 251
E L + EE R +++ E+RE E+E +R+ + K + E +EL +RM
Sbjct: 1339 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1398
Query: 252 EE--RNREKAEDRAARER-IKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVK 308
EE R E A D ++R I++++ R A + EAA+ + L ++ V+
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR 1458
Query: 309 RESYARER 316
+ A ER
Sbjct: 1459 LQLEATER 1466
Score = 34.3 bits (77), Expect = 0.28
Identities = 34/139 (24%), Positives = 75/139 (53%), Gaps = 16/139 (11%)
Query: 195 LNIRVERL-TKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRK----QEEELTKR 249
L+ ++RL + E R+ + EEE ++ ++E K ++ + + ++++ T+R
Sbjct: 2205 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2264
Query: 250 MLEE---RNREKAEDRA-----ARE--RIKQQIALDRAERAARFAKT-KEEVEAAKAAAL 298
L+E + ++ AE+ A A+E R++Q D A++ A K KE+++A + A
Sbjct: 2265 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2324
Query: 299 LAKQAEMEVKRESYARERS 317
L +AE+ +++ A+E++
Sbjct: 2325 LKAEAELLQQQKELAQEQA 2343
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 51.6 bits (122), Expect = 2e-06
Identities = 66/305 (21%), Positives = 128/305 (41%), Gaps = 46/305 (15%)
Query: 118 ETSVANGSQSESSVSTPSASFEPNNTCENSQSRNAEL-CEIPPTSDTKSDTATGGESAGH 176
E ++ Q E + ASFE + + AEL E+ DT E A
Sbjct: 1918 EDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGRIRSNAEDTLRSKEQAEL 1971
Query: 177 ATSSQEPSGCSDQRPAEDLNIRVER-LTKKLEERREEKRKEEEQREIKKEIERRKTGKEM 235
+ Q ++R + RV++ L + E R+ K EE +K ++E + +E
Sbjct: 1972 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2031
Query: 236 LDYKRKQEEELTKRMLEERNR--EKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAA 293
+ + ++ +L + ++R + EKA A +++ +Q++ + + + + E EAA
Sbjct: 2032 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQK-EQELQQTLQQEQSVLDQLRGEAEAA 2090
Query: 294 KAAALLAKQAEMEVKRES--------------YARERSTVARIQFRL------------- 326
+ AA A++A ++ +RE+ + E AR Q +
Sbjct: 2091 RRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2150
Query: 327 -----PDGSSFTNQFPSDAPLEEARQFAAQTV-GNTYGNFSLATMFPRREFTKEDYKKKL 380
+ ++ + +DA +E+ ++FA QT+ L T+ R + + D++K L
Sbjct: 2151 ARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTL--RLQLEETDHQKNL 2208
Query: 381 LDLEL 385
LD EL
Sbjct: 2209 LDEEL 2213
Score = 46.2 bits (108), Expect = 7e-05
Identities = 31/116 (26%), Positives = 61/116 (52%), Gaps = 3/116 (2%)
Query: 209 RREEKRKEEEQREIKKEIER-RKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARER 267
R + E ++R+ ++E ER R+ ++ KR+ E EL R+ E + + RA +
Sbjct: 1483 RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQAL 1542
Query: 268 IKQQIALDRAERAARFAKTK--EEVEAAKAAALLAKQAEMEVKRESYARERSTVAR 321
+ ++ + AER R A+ + +V+ A A + +AE++ KR S+A + + + R
Sbjct: 1543 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1598
Score = 40.8 bits (94), Expect = 0.003
Identities = 38/154 (24%), Positives = 71/154 (46%), Gaps = 25/154 (16%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQRE-IKKEIER-----------RKTGKEML 236
+R ++ ++ V +L ++ E R +++ + E RE ++E+ER R +E+
Sbjct: 1597 ERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1656
Query: 237 DYK-------RKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEE 289
K KQ+EE + E R R KAE++A R+R ++A E+ + A+ +
Sbjct: 1657 QQKSLAQAEAEKQKEEAER---EARRRGKAEEQAVRQR---ELAEQELEKQRQLAEGTAQ 1710
Query: 290 VEAAKAAALLAKQAEMEVKRESYARERSTVARIQ 323
A L+ +AE E + +AR+Q
Sbjct: 1711 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1744
Score = 40.4 bits (93), Expect = 0.004
Identities = 49/257 (19%), Positives = 104/257 (40%), Gaps = 8/257 (3%)
Query: 97 VSADELVTRIHKVRQMHLLKSETSVANGSQS-ESSVSTPSASF-EPNNTCENS-QSRNAE 153
+ A+E R+ + + + ++ +S E+ + + ASF E E S Q +
Sbjct: 1547 LQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1606
Query: 154 LCEIPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLT--KKLEERRE 211
+ ++ ++ ++ E A + A L ++ E + K L +
Sbjct: 1607 VAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEA 1666
Query: 212 EKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQ 271
EK+KEE +RE ++ R K ++ + + E+EL K+ + A +E I+ +
Sbjct: 1667 EKQKEEAEREARR---RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1723
Query: 272 IALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSS 331
++ E+ + + + +AAA K+ E+E + E + + R + S
Sbjct: 1724 AETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESR 1783
Query: 332 FTNQFPSDAPLEEARQF 348
T++ EA +F
Sbjct: 1784 STSEKSKQRLEAEAGRF 1800
Score = 40.4 bits (93), Expect = 0.004
Identities = 27/92 (29%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Query: 207 EERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRA-AR 265
++R++++ ++E QR + E R+ E + R+++EEL + LE++ R++ E A
Sbjct: 2538 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL--QQLEQQRRQQEELLAEEN 2595
Query: 266 ERIKQQIALDRAERAARFAKTKEEVEAAKAAA 297
+R+++Q+ L + A A + EEV A++ AA
Sbjct: 2596 QRLREQLQLLEEQHRAALAHS-EEVTASQVAA 2626
Score = 37.4 bits (85), Expect = 0.032
Identities = 44/233 (18%), Positives = 93/233 (39%), Gaps = 22/233 (9%)
Query: 99 ADELVTRIHKVRQMHLLKSETSVANGSQSESSVSTPSASFEPNNTCE-NSQSRNAELCE- 156
A+ + + Q +++ E + + Q + S+ ++ E +++R AE E
Sbjct: 1390 AEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER 1449
Query: 157 -----------IPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKK 205
+ + G E A ++ + +R A++ ERL ++
Sbjct: 1450 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE---EAERLRRQ 1506
Query: 206 LEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAAR 265
+++ + KR+ E + R K E K++ + L + L+ E+ +A
Sbjct: 1507 VQDESQRKRQAEVEL-----ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEV 1561
Query: 266 ERIKQ-QIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERS 317
ER +Q Q+AL+ A+R+A + A+ A L + + E + RE +
Sbjct: 1562 ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1614
Score = 37.0 bits (84), Expect = 0.042
Identities = 40/149 (26%), Positives = 70/149 (46%), Gaps = 15/149 (10%)
Query: 177 ATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEML 236
A +E + + +R ++L + ++ ++E K + EE+ E +++ E
Sbjct: 1741 ARLQREAAAATQKR--QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAG 1798
Query: 237 DYKRKQEEELTKRMLEE---RNREKAEDRAARERIKQQIALDRAERAARFAK-TKEEVEA 292
++ EE R L E R R+ AE+ AAR+R + + L AE+ A + T+ + EA
Sbjct: 1799 RFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVL--AEKLAAIGEATRLKTEA 1856
Query: 293 AKAAALLAKQAEMEVKR-----ESYARER 316
AL K+AE E R E++ R R
Sbjct: 1857 --EIALKEKEAENERLRRLAEDEAFQRRR 1883
Score = 35.0 bits (79), Expect = 0.16
Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 11/128 (8%)
Query: 200 ERLTKKLEERREEKRKEEEQREIKKEIE-----RRKTGKEMLDYKRKQE---EELTKRML 251
E L + EE R +++ E+RE E+E +R+ + K + E +EL +RM
Sbjct: 1343 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1402
Query: 252 EE--RNREKAEDRAARER-IKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVK 308
EE R E A D ++R I++++ R A + EAA+ + L ++ V+
Sbjct: 1403 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR 1462
Query: 309 RESYARER 316
+ A ER
Sbjct: 1463 LQLEATER 1470
Score = 34.3 bits (77), Expect = 0.28
Identities = 34/139 (24%), Positives = 75/139 (53%), Gaps = 16/139 (11%)
Query: 195 LNIRVERL-TKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRK----QEEELTKR 249
L+ ++RL + E R+ + EEE ++ ++E K ++ + + ++++ T+R
Sbjct: 2209 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2268
Query: 250 MLEE---RNREKAEDRA-----ARE--RIKQQIALDRAERAARFAKT-KEEVEAAKAAAL 298
L+E + ++ AE+ A A+E R++Q D A++ A K KE+++A + A
Sbjct: 2269 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2328
Query: 299 LAKQAEMEVKRESYARERS 317
L +AE+ +++ A+E++
Sbjct: 2329 LKAEAELLQQQKELAQEQA 2347
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 51.6 bits (122), Expect = 2e-06
Identities = 66/305 (21%), Positives = 128/305 (41%), Gaps = 46/305 (15%)
Query: 118 ETSVANGSQSESSVSTPSASFEPNNTCENSQSRNAEL-CEIPPTSDTKSDTATGGESAGH 176
E ++ Q E + ASFE + + AEL E+ DT E A
Sbjct: 1914 EDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGRIRSNAEDTLRSKEQAEL 1967
Query: 177 ATSSQEPSGCSDQRPAEDLNIRVER-LTKKLEERREEKRKEEEQREIKKEIERRKTGKEM 235
+ Q ++R + RV++ L + E R+ K EE +K ++E + +E
Sbjct: 1968 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2027
Query: 236 LDYKRKQEEELTKRMLEERNR--EKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAA 293
+ + ++ +L + ++R + EKA A +++ +Q++ + + + + E EAA
Sbjct: 2028 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQK-EQELQQTLQQEQSVLDQLRGEAEAA 2086
Query: 294 KAAALLAKQAEMEVKRES--------------YARERSTVARIQFRL------------- 326
+ AA A++A ++ +RE+ + E AR Q +
Sbjct: 2087 RRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2146
Query: 327 -----PDGSSFTNQFPSDAPLEEARQFAAQTV-GNTYGNFSLATMFPRREFTKEDYKKKL 380
+ ++ + +DA +E+ ++FA QT+ L T+ R + + D++K L
Sbjct: 2147 ARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTL--RLQLEETDHQKNL 2204
Query: 381 LDLEL 385
LD EL
Sbjct: 2205 LDEEL 2209
Score = 46.2 bits (108), Expect = 7e-05
Identities = 31/116 (26%), Positives = 61/116 (52%), Gaps = 3/116 (2%)
Query: 209 RREEKRKEEEQREIKKEIER-RKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARER 267
R + E ++R+ ++E ER R+ ++ KR+ E EL R+ E + + RA +
Sbjct: 1479 RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQAL 1538
Query: 268 IKQQIALDRAERAARFAKTK--EEVEAAKAAALLAKQAEMEVKRESYARERSTVAR 321
+ ++ + AER R A+ + +V+ A A + +AE++ KR S+A + + + R
Sbjct: 1539 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1594
Score = 40.8 bits (94), Expect = 0.003
Identities = 38/154 (24%), Positives = 71/154 (46%), Gaps = 25/154 (16%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQRE-IKKEIER-----------RKTGKEML 236
+R ++ ++ V +L ++ E R +++ + E RE ++E+ER R +E+
Sbjct: 1593 ERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1652
Query: 237 DYK-------RKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEE 289
K KQ+EE + E R R KAE++A R+R ++A E+ + A+ +
Sbjct: 1653 QQKSLAQAEAEKQKEEAER---EARRRGKAEEQAVRQR---ELAEQELEKQRQLAEGTAQ 1706
Query: 290 VEAAKAAALLAKQAEMEVKRESYARERSTVARIQ 323
A L+ +AE E + +AR+Q
Sbjct: 1707 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1740
Score = 40.4 bits (93), Expect = 0.004
Identities = 49/257 (19%), Positives = 104/257 (40%), Gaps = 8/257 (3%)
Query: 97 VSADELVTRIHKVRQMHLLKSETSVANGSQS-ESSVSTPSASF-EPNNTCENS-QSRNAE 153
+ A+E R+ + + + ++ +S E+ + + ASF E E S Q +
Sbjct: 1543 LQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1602
Query: 154 LCEIPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLT--KKLEERRE 211
+ ++ ++ ++ E A + A L ++ E + K L +
Sbjct: 1603 VAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEA 1662
Query: 212 EKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQ 271
EK+KEE +RE ++ R K ++ + + E+EL K+ + A +E I+ +
Sbjct: 1663 EKQKEEAEREARR---RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1719
Query: 272 IALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSS 331
++ E+ + + + +AAA K+ E+E + E + + R + S
Sbjct: 1720 AETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESR 1779
Query: 332 FTNQFPSDAPLEEARQF 348
T++ EA +F
Sbjct: 1780 STSEKSKQRLEAEAGRF 1796
Score = 40.4 bits (93), Expect = 0.004
Identities = 27/92 (29%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Query: 207 EERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRA-AR 265
++R++++ ++E QR + E R+ E + R+++EEL + LE++ R++ E A
Sbjct: 2534 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL--QQLEQQRRQQEELLAEEN 2591
Query: 266 ERIKQQIALDRAERAARFAKTKEEVEAAKAAA 297
+R+++Q+ L + A A + EEV A++ AA
Sbjct: 2592 QRLREQLQLLEEQHRAALAHS-EEVTASQVAA 2622
Score = 37.4 bits (85), Expect = 0.032
Identities = 44/233 (18%), Positives = 93/233 (39%), Gaps = 22/233 (9%)
Query: 99 ADELVTRIHKVRQMHLLKSETSVANGSQSESSVSTPSASFEPNNTCE-NSQSRNAELCE- 156
A+ + + Q +++ E + + Q + S+ ++ E +++R AE E
Sbjct: 1386 AEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER 1445
Query: 157 -----------IPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKK 205
+ + G E A ++ + +R A++ ERL ++
Sbjct: 1446 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE---EAERLRRQ 1502
Query: 206 LEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAAR 265
+++ + KR+ E + R K E K++ + L + L+ E+ +A
Sbjct: 1503 VQDESQRKRQAEVEL-----ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEV 1557
Query: 266 ERIKQ-QIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERS 317
ER +Q Q+AL+ A+R+A + A+ A L + + E + RE +
Sbjct: 1558 ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1610
Score = 37.0 bits (84), Expect = 0.042
Identities = 40/149 (26%), Positives = 70/149 (46%), Gaps = 15/149 (10%)
Query: 177 ATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEML 236
A +E + + +R ++L + ++ ++E K + EE+ E +++ E
Sbjct: 1737 ARLQREAAAATQKR--QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAG 1794
Query: 237 DYKRKQEEELTKRMLEE---RNREKAEDRAARERIKQQIALDRAERAARFAK-TKEEVEA 292
++ EE R L E R R+ AE+ AAR+R + + L AE+ A + T+ + EA
Sbjct: 1795 RFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVL--AEKLAAIGEATRLKTEA 1852
Query: 293 AKAAALLAKQAEMEVKR-----ESYARER 316
AL K+AE E R E++ R R
Sbjct: 1853 --EIALKEKEAENERLRRLAEDEAFQRRR 1879
Score = 35.0 bits (79), Expect = 0.16
Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 11/128 (8%)
Query: 200 ERLTKKLEERREEKRKEEEQREIKKEIE-----RRKTGKEMLDYKRKQE---EELTKRML 251
E L + EE R +++ E+RE E+E +R+ + K + E +EL +RM
Sbjct: 1339 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1398
Query: 252 EE--RNREKAEDRAARER-IKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVK 308
EE R E A D ++R I++++ R A + EAA+ + L ++ V+
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR 1458
Query: 309 RESYARER 316
+ A ER
Sbjct: 1459 LQLEATER 1466
Score = 34.3 bits (77), Expect = 0.28
Identities = 34/139 (24%), Positives = 75/139 (53%), Gaps = 16/139 (11%)
Query: 195 LNIRVERL-TKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRK----QEEELTKR 249
L+ ++RL + E R+ + EEE ++ ++E K ++ + + ++++ T+R
Sbjct: 2205 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2264
Query: 250 MLEE---RNREKAEDRA-----ARE--RIKQQIALDRAERAARFAKT-KEEVEAAKAAAL 298
L+E + ++ AE+ A A+E R++Q D A++ A K KE+++A + A
Sbjct: 2265 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2324
Query: 299 LAKQAEMEVKRESYARERS 317
L +AE+ +++ A+E++
Sbjct: 2325 LKAEAELLQQQKELAQEQA 2343
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 51.6 bits (122), Expect = 2e-06
Identities = 66/305 (21%), Positives = 128/305 (41%), Gaps = 46/305 (15%)
Query: 118 ETSVANGSQSESSVSTPSASFEPNNTCENSQSRNAEL-CEIPPTSDTKSDTATGGESAGH 176
E ++ Q E + ASFE + + AEL E+ DT E A
Sbjct: 1882 EDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGRIRSNAEDTLRSKEQAEL 1935
Query: 177 ATSSQEPSGCSDQRPAEDLNIRVER-LTKKLEERREEKRKEEEQREIKKEIERRKTGKEM 235
+ Q ++R + RV++ L + E R+ K EE +K ++E + +E
Sbjct: 1936 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRER 1995
Query: 236 LDYKRKQEEELTKRMLEERNR--EKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAA 293
+ + ++ +L + ++R + EKA A +++ +Q++ + + + + E EAA
Sbjct: 1996 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQK-EQELQQTLQQEQSVLDQLRGEAEAA 2054
Query: 294 KAAALLAKQAEMEVKRES--------------YARERSTVARIQFRL------------- 326
+ AA A++A ++ +RE+ + E AR Q +
Sbjct: 2055 RRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2114
Query: 327 -----PDGSSFTNQFPSDAPLEEARQFAAQTV-GNTYGNFSLATMFPRREFTKEDYKKKL 380
+ ++ + +DA +E+ ++FA QT+ L T+ R + + D++K L
Sbjct: 2115 ARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTL--RLQLEETDHQKNL 2172
Query: 381 LDLEL 385
LD EL
Sbjct: 2173 LDEEL 2177
Score = 46.2 bits (108), Expect = 7e-05
Identities = 31/116 (26%), Positives = 61/116 (52%), Gaps = 3/116 (2%)
Query: 209 RREEKRKEEEQREIKKEIER-RKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARER 267
R + E ++R+ ++E ER R+ ++ KR+ E EL R+ E + + RA +
Sbjct: 1447 RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQAL 1506
Query: 268 IKQQIALDRAERAARFAKTK--EEVEAAKAAALLAKQAEMEVKRESYARERSTVAR 321
+ ++ + AER R A+ + +V+ A A + +AE++ KR S+A + + + R
Sbjct: 1507 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1562
Score = 40.8 bits (94), Expect = 0.003
Identities = 38/154 (24%), Positives = 71/154 (46%), Gaps = 25/154 (16%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQRE-IKKEIER-----------RKTGKEML 236
+R ++ ++ V +L ++ E R +++ + E RE ++E+ER R +E+
Sbjct: 1561 ERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1620
Query: 237 DYK-------RKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEE 289
K KQ+EE + E R R KAE++A R+R ++A E+ + A+ +
Sbjct: 1621 QQKSLAQAEAEKQKEEAER---EARRRGKAEEQAVRQR---ELAEQELEKQRQLAEGTAQ 1674
Query: 290 VEAAKAAALLAKQAEMEVKRESYARERSTVARIQ 323
A L+ +AE E + +AR+Q
Sbjct: 1675 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1708
Score = 40.4 bits (93), Expect = 0.004
Identities = 49/257 (19%), Positives = 104/257 (40%), Gaps = 8/257 (3%)
Query: 97 VSADELVTRIHKVRQMHLLKSETSVANGSQS-ESSVSTPSASF-EPNNTCENS-QSRNAE 153
+ A+E R+ + + + ++ +S E+ + + ASF E E S Q +
Sbjct: 1511 LQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1570
Query: 154 LCEIPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLT--KKLEERRE 211
+ ++ ++ ++ E A + A L ++ E + K L +
Sbjct: 1571 VAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEA 1630
Query: 212 EKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQ 271
EK+KEE +RE ++ R K ++ + + E+EL K+ + A +E I+ +
Sbjct: 1631 EKQKEEAEREARR---RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1687
Query: 272 IALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSS 331
++ E+ + + + +AAA K+ E+E + E + + R + S
Sbjct: 1688 AETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESR 1747
Query: 332 FTNQFPSDAPLEEARQF 348
T++ EA +F
Sbjct: 1748 STSEKSKQRLEAEAGRF 1764
Score = 40.4 bits (93), Expect = 0.004
Identities = 27/92 (29%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Query: 207 EERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRA-AR 265
++R++++ ++E QR + E R+ E + R+++EEL + LE++ R++ E A
Sbjct: 2502 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL--QQLEQQRRQQEELLAEEN 2559
Query: 266 ERIKQQIALDRAERAARFAKTKEEVEAAKAAA 297
+R+++Q+ L + A A + EEV A++ AA
Sbjct: 2560 QRLREQLQLLEEQHRAALAHS-EEVTASQVAA 2590
Score = 37.4 bits (85), Expect = 0.032
Identities = 44/233 (18%), Positives = 93/233 (39%), Gaps = 22/233 (9%)
Query: 99 ADELVTRIHKVRQMHLLKSETSVANGSQSESSVSTPSASFEPNNTCE-NSQSRNAELCE- 156
A+ + + Q +++ E + + Q + S+ ++ E +++R AE E
Sbjct: 1354 AEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER 1413
Query: 157 -----------IPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKK 205
+ + G E A ++ + +R A++ ERL ++
Sbjct: 1414 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE---EAERLRRQ 1470
Query: 206 LEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAAR 265
+++ + KR+ E + R K E K++ + L + L+ E+ +A
Sbjct: 1471 VQDESQRKRQAEVEL-----ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEV 1525
Query: 266 ERIKQ-QIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERS 317
ER +Q Q+AL+ A+R+A + A+ A L + + E + RE +
Sbjct: 1526 ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1578
Score = 37.0 bits (84), Expect = 0.042
Identities = 40/149 (26%), Positives = 70/149 (46%), Gaps = 15/149 (10%)
Query: 177 ATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEML 236
A +E + + +R ++L + ++ ++E K + EE+ E +++ E
Sbjct: 1705 ARLQREAAAATQKR--QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAG 1762
Query: 237 DYKRKQEEELTKRMLEE---RNREKAEDRAARERIKQQIALDRAERAARFAK-TKEEVEA 292
++ EE R L E R R+ AE+ AAR+R + + L AE+ A + T+ + EA
Sbjct: 1763 RFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVL--AEKLAAIGEATRLKTEA 1820
Query: 293 AKAAALLAKQAEMEVKR-----ESYARER 316
AL K+AE E R E++ R R
Sbjct: 1821 --EIALKEKEAENERLRRLAEDEAFQRRR 1847
Score = 35.0 bits (79), Expect = 0.16
Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 11/128 (8%)
Query: 200 ERLTKKLEERREEKRKEEEQREIKKEIE-----RRKTGKEMLDYKRKQE---EELTKRML 251
E L + EE R +++ E+RE E+E +R+ + K + E +EL +RM
Sbjct: 1307 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1366
Query: 252 EE--RNREKAEDRAARER-IKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVK 308
EE R E A D ++R I++++ R A + EAA+ + L ++ V+
Sbjct: 1367 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR 1426
Query: 309 RESYARER 316
+ A ER
Sbjct: 1427 LQLEATER 1434
Score = 34.3 bits (77), Expect = 0.28
Identities = 34/139 (24%), Positives = 75/139 (53%), Gaps = 16/139 (11%)
Query: 195 LNIRVERL-TKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRK----QEEELTKR 249
L+ ++RL + E R+ + EEE ++ ++E K ++ + + ++++ T+R
Sbjct: 2173 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2232
Query: 250 MLEE---RNREKAEDRA-----ARE--RIKQQIALDRAERAARFAKT-KEEVEAAKAAAL 298
L+E + ++ AE+ A A+E R++Q D A++ A K KE+++A + A
Sbjct: 2233 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2292
Query: 299 LAKQAEMEVKRESYARERS 317
L +AE+ +++ A+E++
Sbjct: 2293 LKAEAELLQQQKELAQEQA 2311
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 51.6 bits (122), Expect = 2e-06
Identities = 66/305 (21%), Positives = 128/305 (41%), Gaps = 46/305 (15%)
Query: 118 ETSVANGSQSESSVSTPSASFEPNNTCENSQSRNAEL-CEIPPTSDTKSDTATGGESAGH 176
E ++ Q E + ASFE + + AEL E+ DT E A
Sbjct: 2051 EDTLRQRRQVEEEILALKASFE------KAAAGKAELELELGRIRSNAEDTLRSKEQAEL 2104
Query: 177 ATSSQEPSGCSDQRPAEDLNIRVER-LTKKLEERREEKRKEEEQREIKKEIERRKTGKEM 235
+ Q ++R + RV++ L + E R+ K EE +K ++E + +E
Sbjct: 2105 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2164
Query: 236 LDYKRKQEEELTKRMLEERNR--EKAEDRAARERIKQQIALDRAERAARFAKTKEEVEAA 293
+ + ++ +L + ++R + EKA A +++ +Q++ + + + + E EAA
Sbjct: 2165 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQK-EQELQQTLQQEQSVLDQLRGEAEAA 2223
Query: 294 KAAALLAKQAEMEVKRES--------------YARERSTVARIQFRL------------- 326
+ AA A++A ++ +RE+ + E AR Q +
Sbjct: 2224 RRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2283
Query: 327 -----PDGSSFTNQFPSDAPLEEARQFAAQTV-GNTYGNFSLATMFPRREFTKEDYKKKL 380
+ ++ + +DA +E+ ++FA QT+ L T+ R + + D++K L
Sbjct: 2284 ARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTL--RLQLEETDHQKNL 2341
Query: 381 LDLEL 385
LD EL
Sbjct: 2342 LDEEL 2346
Score = 46.2 bits (108), Expect = 7e-05
Identities = 31/116 (26%), Positives = 61/116 (52%), Gaps = 3/116 (2%)
Query: 209 RREEKRKEEEQREIKKEIER-RKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARER 267
R + E ++R+ ++E ER R+ ++ KR+ E EL R+ E + + RA +
Sbjct: 1616 RARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQAL 1675
Query: 268 IKQQIALDRAERAARFAKTK--EEVEAAKAAALLAKQAEMEVKRESYARERSTVAR 321
+ ++ + AER R A+ + +V+ A A + +AE++ KR S+A + + + R
Sbjct: 1676 EELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1731
Score = 40.8 bits (94), Expect = 0.003
Identities = 38/154 (24%), Positives = 71/154 (46%), Gaps = 25/154 (16%)
Query: 189 QRPAEDLNIRVERLTKKLEERREEKRKEEEQRE-IKKEIER-----------RKTGKEML 236
+R ++ ++ V +L ++ E R +++ + E RE ++E+ER R +E+
Sbjct: 1730 ERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1789
Query: 237 DYK-------RKQEEELTKRMLEERNREKAEDRAARERIKQQIALDRAERAARFAKTKEE 289
K KQ+EE + E R R KAE++A R+R ++A E+ + A+ +
Sbjct: 1790 QQKSLAQAEAEKQKEEAER---EARRRGKAEEQAVRQR---ELAEQELEKQRQLAEGTAQ 1843
Query: 290 VEAAKAAALLAKQAEMEVKRESYARERSTVARIQ 323
A L+ +AE E + +AR+Q
Sbjct: 1844 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1877
Score = 40.4 bits (93), Expect = 0.004
Identities = 49/257 (19%), Positives = 104/257 (40%), Gaps = 8/257 (3%)
Query: 97 VSADELVTRIHKVRQMHLLKSETSVANGSQS-ESSVSTPSASF-EPNNTCENS-QSRNAE 153
+ A+E R+ + + + ++ +S E+ + + ASF E E S Q +
Sbjct: 1680 LQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1739
Query: 154 LCEIPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLT--KKLEERRE 211
+ ++ ++ ++ E A + A L ++ E + K L +
Sbjct: 1740 VAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEA 1799
Query: 212 EKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAARERIKQQ 271
EK+KEE +RE ++ R K ++ + + E+EL K+ + A +E I+ +
Sbjct: 1800 EKQKEEAEREARR---RGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLR 1856
Query: 272 IALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERSTVARIQFRLPDGSS 331
++ E+ + + + +AAA K+ E+E + E + + R + S
Sbjct: 1857 AETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESR 1916
Query: 332 FTNQFPSDAPLEEARQF 348
T++ EA +F
Sbjct: 1917 STSEKSKQRLEAEAGRF 1933
Score = 40.4 bits (93), Expect = 0.004
Identities = 27/92 (29%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Query: 207 EERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRA-AR 265
++R++++ ++E QR + E R+ E + R+++EEL + LE++ R++ E A
Sbjct: 2671 QQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL--QQLEQQRRQQEELLAEEN 2728
Query: 266 ERIKQQIALDRAERAARFAKTKEEVEAAKAAA 297
+R+++Q+ L + A A + EEV A++ AA
Sbjct: 2729 QRLREQLQLLEEQHRAALAHS-EEVTASQVAA 2759
Score = 37.4 bits (85), Expect = 0.032
Identities = 44/233 (18%), Positives = 93/233 (39%), Gaps = 22/233 (9%)
Query: 99 ADELVTRIHKVRQMHLLKSETSVANGSQSESSVSTPSASFEPNNTCE-NSQSRNAELCE- 156
A+ + + Q +++ E + + Q + S+ ++ E +++R AE E
Sbjct: 1523 AEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER 1582
Query: 157 -----------IPPTSDTKSDTATGGESAGHATSSQEPSGCSDQRPAEDLNIRVERLTKK 205
+ + G E A ++ + +R A++ ERL ++
Sbjct: 1583 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE---EAERLRRQ 1639
Query: 206 LEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRKQEEELTKRMLEERNREKAEDRAAR 265
+++ + KR+ E + R K E K++ + L + L+ E+ +A
Sbjct: 1640 VQDESQRKRQAEVEL-----ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEV 1694
Query: 266 ERIKQ-QIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVKRESYARERS 317
ER +Q Q+AL+ A+R+A + A+ A L + + E + RE +
Sbjct: 1695 ERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1747
Score = 37.0 bits (84), Expect = 0.042
Identities = 40/149 (26%), Positives = 70/149 (46%), Gaps = 15/149 (10%)
Query: 177 ATSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQREIKKEIERRKTGKEML 236
A +E + + +R ++L + ++ ++E K + EE+ E +++ E
Sbjct: 1874 ARLQREAAAATQKR--QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAG 1931
Query: 237 DYKRKQEEELTKRMLEE---RNREKAEDRAARERIKQQIALDRAERAARFAK-TKEEVEA 292
++ EE R L E R R+ AE+ AAR+R + + L AE+ A + T+ + EA
Sbjct: 1932 RFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVL--AEKLAAIGEATRLKTEA 1989
Query: 293 AKAAALLAKQAEMEVKR-----ESYARER 316
AL K+AE E R E++ R R
Sbjct: 1990 --EIALKEKEAENERLRRLAEDEAFQRRR 2016
Score = 35.0 bits (79), Expect = 0.16
Identities = 35/128 (27%), Positives = 60/128 (46%), Gaps = 11/128 (8%)
Query: 200 ERLTKKLEERREEKRKEEEQREIKKEIE-----RRKTGKEMLDYKRKQE---EELTKRML 251
E L + EE R +++ E+RE E+E +R+ + K + E +EL +RM
Sbjct: 1476 ETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ 1535
Query: 252 EE--RNREKAEDRAARER-IKQQIALDRAERAARFAKTKEEVEAAKAAALLAKQAEMEVK 308
EE R E A D ++R I++++ R A + EAA+ + L ++ V+
Sbjct: 1536 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR 1595
Query: 309 RESYARER 316
+ A ER
Sbjct: 1596 LQLEATER 1603
Score = 34.3 bits (77), Expect = 0.28
Identities = 34/139 (24%), Positives = 75/139 (53%), Gaps = 16/139 (11%)
Query: 195 LNIRVERL-TKKLEERREEKRKEEEQREIKKEIERRKTGKEMLDYKRK----QEEELTKR 249
L+ ++RL + E R+ + EEE ++ ++E K ++ + + ++++ T+R
Sbjct: 2342 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2401
Query: 250 MLEE---RNREKAEDRA-----ARE--RIKQQIALDRAERAARFAKT-KEEVEAAKAAAL 298
L+E + ++ AE+ A A+E R++Q D A++ A K KE+++A + A
Sbjct: 2402 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2461
Query: 299 LAKQAEMEVKRESYARERS 317
L +AE+ +++ A+E++
Sbjct: 2462 LKAEAELLQQQKELAQEQA 2480
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,103,211
Number of Sequences: 37866
Number of extensions: 912809
Number of successful extensions: 18948
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 458
Number of HSP's successfully gapped in prelim test: 869
Number of HSP's that attempted gapping in prelim test: 7141
Number of HSP's gapped (non-prelim): 5850
length of query: 508
length of database: 18,247,518
effective HSP length: 107
effective length of query: 401
effective length of database: 14,195,856
effective search space: 5692538256
effective search space used: 5692538256
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.