Search of human proteins with 24234688

Search of human proteins with 24234688

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
         (679 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]      1318   0.0  
gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]                 598   e-171
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]        576   e-164
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]                 573   e-163
gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]       568   e-162
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]               567   e-161
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]               567   e-161
gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]           562   e-160
gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]       479   e-135
gi|48928056 heat shock protein 70kDa family member 13 precursor ...   244   2e-64
gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]      243   6e-64
gi|42544159 heat shock 105kD [Homo sapiens]                           238   1e-62
gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]            226   4e-59
gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]                 219   7e-57
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]          168   2e-41
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]            168   2e-41
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           42   0.002
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           42   0.002
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    41   0.003
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    39   0.016
gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo sa...    39   0.016
gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo s...    39   0.016
gi|34577114 cytomatrix protein p110 [Homo sapiens]                     38   0.035
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    37   0.060
gi|118498362 kinectin 1 isoform b [Homo sapiens]                       37   0.078
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       37   0.078
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       37   0.078
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        37   0.078
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    37   0.078
gi|32171186 B-cell receptor-associated protein 31 isoform b [Hom...    37   0.078

>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
          Length = 679

 Score = 1318 bits (3410), Expect = 0.0
 Identities = 679/679 (100%), Positives = 679/679 (100%)

Query: 1   MISASRAAAARLVGAAASRGPTAARHQDSWNGLSHEAFRLVSRRDYASEAIKGAVVGIDL 60
           MISASRAAAARLVGAAASRGPTAARHQDSWNGLSHEAFRLVSRRDYASEAIKGAVVGIDL
Sbjct: 1   MISASRAAAARLVGAAASRGPTAARHQDSWNGLSHEAFRLVSRRDYASEAIKGAVVGIDL 60

Query: 61  GTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYAT 120
           GTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYAT
Sbjct: 61  GTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYAT 120

Query: 121 KRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAEN 180
           KRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAEN
Sbjct: 121 KRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAEN 180

Query: 181 YLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVI 240
           YLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVI
Sbjct: 181 YLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVI 240

Query: 241 AVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTK 300
           AVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTK
Sbjct: 241 AVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTK 300

Query: 301 DNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKLTRAQFEGIVTDLIR 360
           DNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKLTRAQFEGIVTDLIR
Sbjct: 301 DNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKLTRAQFEGIVTDLIR 360

Query: 361 RTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIG 420
           RTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIG
Sbjct: 361 RTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIG 420

Query: 421 AAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQT 480
           AAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQT
Sbjct: 421 AAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQT 480

Query: 481 QVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTG 540
           QVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTG
Sbjct: 481 QVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTG 540

Query: 541 REQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFK 600
           REQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFK
Sbjct: 541 REQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFK 600

Query: 601 DQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASERE 660
           DQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASERE
Sbjct: 601 DQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASERE 660

Query: 661 GSGSSGTGEQKEDQKEEKQ 679
           GSGSSGTGEQKEDQKEEKQ
Sbjct: 661 GSGSSGTGEQKEDQKEEKQ 679


>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
          Length = 654

 Score =  598 bits (1543), Expect = e-171
 Identities = 330/635 (51%), Positives = 436/635 (68%), Gaps = 19/635 (2%)

Query: 53  GAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTN 112
           G VVGIDLGTT SCV V +  + +++ N +G R TPS VAFT +GERL+G  AK Q  +N
Sbjct: 28  GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87

Query: 113 PNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIV-RASNGDAWVEAHG---KLYSPSQIGA 168
           P NT +  KRLIGR ++DP VQ+DIK +PFK+V + +     V+  G   K ++P +I A
Sbjct: 88  PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISA 147

Query: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228
            VL KMKETAE YLG    +AV+TVPAYFND+QRQATKDAG I+GLNV+R+INEPTAAA+
Sbjct: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207

Query: 229 AYGLDKSE-DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIV 287
           AYGLDK E +K I V+DLGGGTFD+S+L I  GVFEV +TNGDT LGGEDFDQ ++ H +
Sbjct: 208 AYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFI 267

Query: 288 KEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKLT 347
           K +K++TG D+ KDN A+Q++R   EKAK  LSS  Q  I +             +  LT
Sbjct: 268 KLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGED----FSETLT 323

Query: 348 RAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF-GRA 406
           RA+FE +  DL R T+ P QK ++D+++ KSDI E++LVGG TR+PK+QQ V++ F G+ 
Sbjct: 324 RAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKE 383

Query: 407 PSKAVNPDEAVAIGAAIQGGVLAGD--VTDVLLLDVTPLSLGIETLGGVFTKLINRNTTI 464
           PS+ +NPDEAVA GAA+Q GVL+GD    D++LLDV PL+LGIET+GGV TKLI RNT +
Sbjct: 384 PSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVV 443

Query: 465 PTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDI 524
           PTKKSQ+FSTA+D Q  V IKV +GER +  DN LLG F L GIPPAPRGVPQIEVTF+I
Sbjct: 444 PTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEI 503

Query: 525 DANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVN 583
           D NGI+ V+A+DKGTG + +I I      L+ ++IE MV +AEK+AEED++ KER++  N
Sbjct: 504 DVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRN 563

Query: 584 MAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQA 643
             E   +  + ++ + K++L      KL  E  +  E    +  E  E+ + A     +A
Sbjct: 564 ELESYAYSLKNQIGD-KEKLG----GKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKA 618

Query: 644 SLKLFEMAYKKMASEREGS-GSSGTGEQKEDQKEE 677
             K  E   + + S+  GS G   TGE+   +K+E
Sbjct: 619 KKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKDE 653


>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
          Length = 646

 Score =  576 bits (1484), Expect = e-164
 Identities = 315/615 (51%), Positives = 418/615 (67%), Gaps = 18/615 (2%)

Query: 52  KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111
           KG  VGIDLGTT SCV V +  + +++ N +G RTTPS VAFT D ERL+G  AK Q   
Sbjct: 3   KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 61

Query: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVR-ASNGDAWVEAHG--KLYSPSQIGA 168
           NP NT +  KRLIGRR+DD  VQ D+K+ PF +V  A      VE  G  K + P ++ +
Sbjct: 62  NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121

Query: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228
            VL KMKE AE YLG T  NAV+TVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAAA+
Sbjct: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181

Query: 229 AYGLDKS--EDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHI 286
           AYGLDK    ++ + ++DLGGGTFD+SIL I+ G+FEVKST GDT LGGEDFD  ++ H 
Sbjct: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241

Query: 287 VKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKL 346
           + EFKR+   D++++  A++R+R A E+AK  LSSS Q  I +  L             +
Sbjct: 242 IAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGID----FYTSI 297

Query: 347 TRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF-GR 405
           TRA+FE +  DL R T+ P +KA++DA++ KS I +++LVGG TR+PK+Q+ +QD F G+
Sbjct: 298 TRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGK 357

Query: 406 APSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLINRN 461
             +K++NPDEAVA GAA+Q  +L+GD    V D+LLLDVTPLSLGIET GGV T LI RN
Sbjct: 358 ELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRN 417

Query: 462 TTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVT 521
           TTIPTK++Q F+T +D Q  V I+V +GER M  DN LLG+F L GIPPAPRGVPQIEVT
Sbjct: 418 TTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVT 477

Query: 522 FDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKERVE 580
           FDIDANGI++VSA DK TG+E +I I    G LSK+DIE MV+ AEKY  ED +++++V 
Sbjct: 478 FDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVS 537

Query: 581 AVNMAEGIIHDTETKMEEFKDQ--LPADECNKLKEEISKMRELLARKDSETGENIRQAAS 638
           + N  E    + +  +E+ K Q  +  ++  K+ ++ +++   L +  +   E       
Sbjct: 538 SKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQK 597

Query: 639 SLQQASLKLFEMAYK 653
            L++    +    Y+
Sbjct: 598 ELEKVCNPIITKLYQ 612


>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
          Length = 639

 Score =  573 bits (1476), Expect = e-163
 Identities = 313/630 (49%), Positives = 416/630 (66%), Gaps = 20/630 (3%)

Query: 52  KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111
           +G  +GIDLGTT SCV V +  + +++ N +G RTTPS VAFT D ERL+G  AK Q   
Sbjct: 4   RGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 62

Query: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIV-RASNGDAWVEAHG--KLYSPSQIGA 168
           NP NT +  KRLIGR+++D  VQ D+K+ PF++V         VE  G  K + P +I +
Sbjct: 63  NPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISS 122

Query: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228
            VL KMKE AE YLG    +AVITVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAAA+
Sbjct: 123 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182

Query: 229 AYGLDKSE----DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLR 284
           AYGLDK      +K + ++DLGGGTFD+SIL I+ G+FEVKST GDT LGGEDFD  ++ 
Sbjct: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVS 242

Query: 285 HIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNM 344
           H+ +EFKR+   D+  +  A++R+R A E+AK  LSSS Q  I +  L            
Sbjct: 243 HLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVD----FYT 298

Query: 345 KLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF- 403
            +TRA+FE +  DL R T+ P +KA++DA++ K  I E++LVGG TR+PK+Q+ +QD F 
Sbjct: 299 SITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFN 358

Query: 404 GRAPSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLIN 459
           G+  +K++NPDEAVA GAA+Q  +L GD    V D+LLLDVTPLSLGIET GGV T LI 
Sbjct: 359 GKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIK 418

Query: 460 RNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIE 519
           RNTTIPTK++Q F+T +D Q+ V ++V +GER M  DN LLG+F L GIPPAPRGVPQIE
Sbjct: 419 RNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIE 478

Query: 520 VTFDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKER 578
           VTFDIDANGI++V+A DK TG+E +I I    G LSKDDI+ MV+ AE+Y  ED   ++R
Sbjct: 479 VTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDR 538

Query: 579 VEAVNMAEGIIHDTETKMEE--FKDQLPADECNKLKEEISKMRELLARKDSETGENIRQA 636
           V A N  E   ++ +  +E+   + ++   + NK+ ++  ++   L R      +     
Sbjct: 539 VAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHK 598

Query: 637 ASSLQQASLKLFEMAYKKMASEREGSGSSG 666
              L++    +    Y+       G G SG
Sbjct: 599 QKELERVCNPIISKLYQGGPGGGSGGGGSG 628


>gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
          Length = 643

 Score =  568 bits (1464), Expect = e-162
 Identities = 317/639 (49%), Positives = 423/639 (66%), Gaps = 22/639 (3%)

Query: 49  EAIKGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQ 108
           +A +   VGIDLGTT SCV V +  + ++L N +G RTTPS VAFT D ERLVG  AK Q
Sbjct: 2   QAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFT-DTERLVGDAAKSQ 60

Query: 109 AVTNPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEA----HGKLYSPS 164
           A  NP+NT +  KRLIGR++ D  VQ D+K+ PF++V +  G   V        K + P 
Sbjct: 61  AALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVV-SEGGKPKVRVCYRGEDKTFYPE 119

Query: 165 QIGAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPT 224
           +I + VL KMKETAE YLG   K+AVITVPAYFNDSQRQATKDAG I+GLNVLR+INEPT
Sbjct: 120 EISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPT 179

Query: 225 AAALAYGLDK--SEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQAL 282
           AAA+AYGLD+  + ++ + ++DLGGGTFD+S+L I  GVFEVK+T GDT LGGEDFD  L
Sbjct: 180 AAAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRL 239

Query: 283 LRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHL 342
           + H ++EF+R+ G DL+ +  AL+R+R A E+AK  LSSS Q  + +  L          
Sbjct: 240 VNHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVD----F 295

Query: 343 NMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDL 402
              +TRA+FE + +DL R T+ P +KA++DA++ K+ I +V+LVGG TR+PKVQ+ +QD 
Sbjct: 296 YTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDF 355

Query: 403 F-GRAPSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKL 457
           F G+  +K++NPDEAVA GAA+Q  VL GD    V D+LLLDV PLSLG+ET GGV T L
Sbjct: 356 FNGKELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTL 415

Query: 458 INRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQ 517
           I RN TIPTK++Q F+T +D Q  V I+V +GER M  DN LLG+F L GIPPAPRGVPQ
Sbjct: 416 IQRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQ 475

Query: 518 IEVTFDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKK 576
           IEVTFDIDANGI+ V+A D+ TG+  +I I    G LSK+++E MV  AE+Y  ED  ++
Sbjct: 476 IEVTFDIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQR 535

Query: 577 ERVEAVNMAEGIIHDTETKMEE--FKDQLPADECNKLKEEISKMRELLARKDSETGENIR 634
           +RV A N  E  +   +  ++E   +D++P ++  K++++  ++   L        E   
Sbjct: 536 DRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYE 595

Query: 635 QAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKED 673
                L+Q    +F   Y        G  S GT  ++ D
Sbjct: 596 HQKRELEQICRPIFSRLYG--GPGVPGGSSCGTQARQGD 632


>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
          Length = 641

 Score =  567 bits (1462), Expect = e-161
 Identities = 315/633 (49%), Positives = 426/633 (67%), Gaps = 31/633 (4%)

Query: 52  KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111
           K A +GIDLGTT SCV V +  + +++ N +G RTTPS VAFT D ERL+G  AK Q   
Sbjct: 3   KAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAL 61

Query: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGD-----AWVEAHGKLYSPSQI 166
           NP NT +  KRLIGR++ DP VQ D+K+ PF+++  ++GD        +   K + P +I
Sbjct: 62  NPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVI--NDGDKPKVQVSYKGETKAFYPEEI 119

Query: 167 GAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAA 226
            + VL KMKE AE YLG+   NAVITVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAA
Sbjct: 120 SSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAA 179

Query: 227 ALAYGLDKSE--DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLR 284
           A+AYGLD++   ++ + ++DLGGGTFD+SIL I  G+FEVK+T GDT LGGEDFD  L+ 
Sbjct: 180 AIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVN 239

Query: 285 HIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNM 344
           H V+EFKR+   D++++  A++R+R A E+AK  LSSS Q  + +  L            
Sbjct: 240 HFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGID----FYT 295

Query: 345 KLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF- 403
            +TRA+FE + +DL R T+ P +KA++DA++ K+ I +++LVGG TR+PKVQ+ +QD F 
Sbjct: 296 SITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFN 355

Query: 404 GRAPSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLIN 459
           GR  +K++NPDEAVA GAA+Q  +L GD    V D+LLLDV PLSLG+ET GGV T LI 
Sbjct: 356 GRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIK 415

Query: 460 RNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIE 519
           RN+TIPTK++Q+F+T +D Q  V I+V +GER M  DN LLG+F L GIPPAPRGVPQIE
Sbjct: 416 RNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIE 475

Query: 520 VTFDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKER 578
           VTFDIDANGI++V+A DK TG+  +I I    G LSK++IE MV+ AEKY  ED  ++ER
Sbjct: 476 VTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRER 535

Query: 579 VEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSET---GENIRQ 635
           V A N  E    + ++ +E+   +    E +K K+ + K +E+++  D+ T    +    
Sbjct: 536 VSAKNALESYAFNMKSAVEDEGLKGKISEADK-KKVLDKCQEVISWLDANTLAEKDEFEH 594

Query: 636 AASSLQQASLKLFEMAYKKMASEREGSGSSGTG 668
               L+Q    +    Y       +G+G  G G
Sbjct: 595 KRKELEQVCNPIISGLY-------QGAGGPGPG 620


>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
          Length = 641

 Score =  567 bits (1462), Expect = e-161
 Identities = 315/633 (49%), Positives = 426/633 (67%), Gaps = 31/633 (4%)

Query: 52  KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111
           K A +GIDLGTT SCV V +  + +++ N +G RTTPS VAFT D ERL+G  AK Q   
Sbjct: 3   KAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAL 61

Query: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGD-----AWVEAHGKLYSPSQI 166
           NP NT +  KRLIGR++ DP VQ D+K+ PF+++  ++GD        +   K + P +I
Sbjct: 62  NPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVI--NDGDKPKVQVSYKGETKAFYPEEI 119

Query: 167 GAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAA 226
            + VL KMKE AE YLG+   NAVITVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAA
Sbjct: 120 SSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAA 179

Query: 227 ALAYGLDKSE--DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLR 284
           A+AYGLD++   ++ + ++DLGGGTFD+SIL I  G+FEVK+T GDT LGGEDFD  L+ 
Sbjct: 180 AIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVN 239

Query: 285 HIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNM 344
           H V+EFKR+   D++++  A++R+R A E+AK  LSSS Q  + +  L            
Sbjct: 240 HFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGID----FYT 295

Query: 345 KLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF- 403
            +TRA+FE + +DL R T+ P +KA++DA++ K+ I +++LVGG TR+PKVQ+ +QD F 
Sbjct: 296 SITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFN 355

Query: 404 GRAPSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLIN 459
           GR  +K++NPDEAVA GAA+Q  +L GD    V D+LLLDV PLSLG+ET GGV T LI 
Sbjct: 356 GRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIK 415

Query: 460 RNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIE 519
           RN+TIPTK++Q+F+T +D Q  V I+V +GER M  DN LLG+F L GIPPAPRGVPQIE
Sbjct: 416 RNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIE 475

Query: 520 VTFDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKER 578
           VTFDIDANGI++V+A DK TG+  +I I    G LSK++IE MV+ AEKY  ED  ++ER
Sbjct: 476 VTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRER 535

Query: 579 VEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSET---GENIRQ 635
           V A N  E    + ++ +E+   +    E +K K+ + K +E+++  D+ T    +    
Sbjct: 536 VSAKNALESYAFNMKSAVEDEGLKGKISEADK-KKVLDKCQEVISWLDANTLAEKDEFEH 594

Query: 636 AASSLQQASLKLFEMAYKKMASEREGSGSSGTG 668
               L+Q    +    Y       +G+G  G G
Sbjct: 595 KRKELEQVCNPIISGLY-------QGAGGPGPG 620


>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
          Length = 641

 Score =  562 bits (1449), Expect = e-160
 Identities = 305/585 (52%), Positives = 408/585 (69%), Gaps = 21/585 (3%)

Query: 52  KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111
           KG  +GIDLGTT SCV V +  + +++ N +G RTTPS VAFT D ERL+G  AK Q   
Sbjct: 5   KGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 63

Query: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAH---GKLYSPSQIGA 168
           NP NT +  KRLIGR+++DP VQ D+K  PF+++        + ++    K + P +I +
Sbjct: 64  NPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISS 123

Query: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228
            VL K+KETAE +LGH   NAVITVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAAA+
Sbjct: 124 MVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 183

Query: 229 AYGLDKSE--DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHI 286
           AYGLDK    ++ + ++DLGGGTFD+SIL I  G+FEVK+T GDT LGGEDFD  L+ H 
Sbjct: 184 AYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHF 243

Query: 287 VKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKL 346
           V+EFKR+   D++++  A++R+R A E+AK  LSSS Q ++ +  L             +
Sbjct: 244 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGID----FYTSI 299

Query: 347 TRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF-GR 405
           TRA+FE +  DL R T+ P +KA++DA++ K+ I +++LVGG TR+PKVQ+ +QD F GR
Sbjct: 300 TRARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGR 359

Query: 406 APSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLINRN 461
             +K++NPDEAVA GAA+Q  +L GD    V D+LLLDV PLSLG+ET GGV T LI RN
Sbjct: 360 DLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRN 419

Query: 462 TTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVT 521
           +TIPTK++Q+F+T +D Q  V I+V +GER M  DN LLG+F L GIPPAPRGVPQIEVT
Sbjct: 420 STIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVT 479

Query: 522 FDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKERVE 580
           FDIDANGI++V+A DK TG+  +I I    G LSK++IE MV +AEKY  ED  ++E++ 
Sbjct: 480 FDIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIA 539

Query: 581 AVNMAEGIIHDTETKM--EEFKDQLPADECNKLKEEISKMRELLA 623
           A N  E    + ++ +  E  K ++   + NK+   + K  ELL+
Sbjct: 540 AKNALESYAFNMKSVVSDEGLKGKISESDKNKI---LDKCNELLS 581


>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
          Length = 493

 Score =  479 bits (1234), Expect = e-135
 Identities = 261/476 (54%), Positives = 334/476 (70%), Gaps = 16/476 (3%)

Query: 52  KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111
           KG  VGIDLGTT SCV V +  + +++ N +G RTTPS VAFT D ERL+G  AK Q   
Sbjct: 3   KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 61

Query: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVR-ASNGDAWVEAHG--KLYSPSQIGA 168
           NP NT +  KRLIGRR+DD  VQ D+K+ PF +V  A      VE  G  K + P ++ +
Sbjct: 62  NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121

Query: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228
            VL KMKE AE YLG T  NAV+TVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAAA+
Sbjct: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181

Query: 229 AYGLDK--SEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHI 286
           AYGLDK    ++ + ++DLGGGTFD+SIL I+ G+FEVKST GDT LGGEDFD  ++ H 
Sbjct: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241

Query: 287 VKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKL 346
           + EFKR+   D++++  A++R+R A E+AK  LSSS Q  I +  L             +
Sbjct: 242 IAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGID----FYTSI 297

Query: 347 TRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF-GR 405
           TRA+FE +  DL R T+ P +KA++DA++ KS I +++LVGG TR+PK+Q+ +QD F G+
Sbjct: 298 TRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGK 357

Query: 406 APSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLINRN 461
             +K++NPDEAVA GAA+Q  +L+GD    V D+LLLDVTPLSLGIET GGV T LI RN
Sbjct: 358 ELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRN 417

Query: 462 TTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPA-PRGVP 516
           TTIPTK++Q F+T +D Q  V I+V +GER M  DN LLG+F L G+P   P G P
Sbjct: 418 TTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473


>gi|48928056 heat shock protein 70kDa family member 13 precursor
           [Homo sapiens]
          Length = 471

 Score =  244 bits (622), Expect = 2e-64
 Identities = 150/420 (35%), Positives = 236/420 (56%), Gaps = 47/420 (11%)

Query: 55  VVGIDLGTTNSCVAVM---EGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111
           V+GIDLGTT   V V     GK  KV+ +  G  + PS+V+FT D +  VG  +   A +
Sbjct: 33  VIGIDLGTTYCSVGVFFPGTGK-VKVIPDENGHISIPSMVSFT-DNDVYVGYESVELADS 90

Query: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKLY--SPSQIGAF 169
           NP NT Y  KR IG+ +   E++ +I   PFK++  +    +     +    SP  +G+ 
Sbjct: 91  NPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVTSNETITVSPEYVGSR 150

Query: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229
           +L+K+KE AE YLG    NAVI+VPA F+  QR +T +A  ++GL +LRVINEPTAAA+A
Sbjct: 151 LLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMA 210

Query: 230 YGLDKSEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKE 289
           YGL K++   + V DLGGGT D+S+L  Q G+F  ++ +G+  LGG+DF+Q LL+++ K+
Sbjct: 211 YGLHKADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQ 270

Query: 290 FKRETGVDLTKDNMALQRVREAAEKAKCELS--SSVQ-----------------TDINLP 330
             +  G   ++    + R+R+A E  K  L+   S Q                 +D  LP
Sbjct: 271 IYQTYGFVPSRKE-EIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELP 329

Query: 331 YLTMDSSGPKHLNM--------------------KLTRAQFEGIVTDLIRRTIAPCQKAM 370
              + S+    +N                     +++R  F+ +  DL ++ + P Q+ +
Sbjct: 330 KDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVL 389

Query: 371 QDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAG 430
           ++  + K++I EV+LVGG TR+P+++Q +Q+ FG+ P+ +V+PD AV  G AIQ G+  G
Sbjct: 390 KEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAIQAGIDGG 449


>gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]
          Length = 509

 Score =  243 bits (619), Expect = 6e-64
 Identities = 159/512 (31%), Positives = 264/512 (51%), Gaps = 24/512 (4%)

Query: 54  AVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNP 113
           A +G+ LG T++CVAV +  +A V+ N  G R TP+VVA++ + E +VG+ AK+  + N 
Sbjct: 2   AAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYS-ENEEIVGLAAKQSRIRNI 60

Query: 114 NNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEA----HGKLYSPSQIGAF 169
           +NT    K+++GR   DP+ QK I      ++   NG    E       K  +P  +   
Sbjct: 61  SNTVMKVKQILGRSSSDPQAQKYIAESKCLVIE-KNGKLRYEIDTGEETKFVNPEDVARL 119

Query: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229
           +  KMKETA + LG  A + VITVP  F + Q+ A  +A + +G NVLR+I+EP+AA LA
Sbjct: 120 IFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLA 179

Query: 230 YGLDKSE---DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHI 286
           YG+ +        I V+ LGG +  +S++E+  G++ V STN D  +GG  F + L +++
Sbjct: 180 YGIGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYL 239

Query: 287 VKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKL 346
             EF+R    D+  +  A+ ++  +AE AK  LS+    +  L  L       +  +  +
Sbjct: 240 ASEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEG----QDFDCNV 295

Query: 347 TRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRA 406
           +RA+FE + + L  + I   +  +     +  DI +V+L GG +R+PK+QQ ++DLF   
Sbjct: 296 SRARFELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAV 355

Query: 407 P-SKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTP---LSLGIETLGGV-FTKL 457
               ++ PDE + IGAAI+ G+L G     V D L+++ +    L  G++  G   FT L
Sbjct: 356 ELLNSIPPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVL 415

Query: 458 INRNTTIPTKKSQVFSTAAD-GQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVP 516
               T +P ++              +E+    G+     + K   Q  L  +     G+ 
Sbjct: 416 FPSGTPLPARRQHTLQAPGSISSVCLELYESDGKNSAKEETK-FAQVVLQDLDKKENGLR 474

Query: 517 QIEVTFDIDANGIVHVSAKDKGTGREQQIVIQ 548
            I     +  +G +HV+  D+ TG+ + I I+
Sbjct: 475 DILAVLTMKRDGSLHVTCTDQETGKCEAISIE 506


>gi|42544159 heat shock 105kD [Homo sapiens]
          Length = 858

 Score =  238 bits (607), Expect = 1e-62
 Identities = 169/582 (29%), Positives = 287/582 (49%), Gaps = 36/582 (6%)

Query: 54  AVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNP 113
           +VVG+D+G+ +  +AV      + + N    R TPSV++F +   R +G+ AK Q +T+ 
Sbjct: 2   SVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKN-RTIGVAAKNQQITHA 60

Query: 114 NNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEA----HGKLYSPSQIGAF 169
           NNT    KR  GR ++DP +QK+ +N+ + +V   NG   ++        L+S  QI A 
Sbjct: 61  NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120

Query: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229
           +L K+KETAEN L     + VI+VP++F D++R++  DA QI GLN LR++N+ TA AL 
Sbjct: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180

Query: 230 YGLDKSE-------DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQAL 282
           YG+ K +        +++   D+G   F +S     KG  +V  T  D FLGG++FD+ L
Sbjct: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240

Query: 283 LRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHL 342
           + H   EFK +  +D      AL R+ +  EK K +L SS  TD  LP         K +
Sbjct: 241 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLK-KLMSSNSTD--LPLNIECFMNDKDV 297

Query: 343 NMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDL 402
           + K+ R+QFE +  +L+++   P    ++   +   D+  V +VGG TR+P V++ +   
Sbjct: 298 SGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKF 357

Query: 403 FGRAPSKAVNPDEAVAIGAAIQGGVL--AGDVTDVLLLDVTPLSLGI------ETLGGVF 454
           FG+  S  +N DEAVA G A+Q  +L  A  V +  + D  P  + +      E   GV 
Sbjct: 358 FGKDISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVH 417

Query: 455 TKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRG 514
            ++ +RN   P  K   F      + +      QG   +      +G+F +  +     G
Sbjct: 418 -EVFSRNHAAPFSKVLTFLRRGPFELEAFYSDPQG---VPYPEAKIGRFVVQNVSAQKDG 473

Query: 515 -VPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDR 573
              +++V   ++ +GI  +S         +++  + +   S+ D+E + +   +  + D+
Sbjct: 474 EKSRVKVKVRVNTHGIFTIST----ASMVEKVPTEENEMSSEADMECLNQRPPENPDTDK 529

Query: 574 RKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEI 615
                V+  N   G     +T  ++     P+ E    + +I
Sbjct: 530 ----NVQQDNSEAGTQPQVQTDAQQTSQSPPSPELTSEENKI 567


>gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]
          Length = 839

 Score =  226 bits (577), Expect = 4e-59
 Identities = 161/588 (27%), Positives = 287/588 (48%), Gaps = 39/588 (6%)

Query: 54  AVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNP 113
           +VVGIDLG  N  +AV      + + N    R TP+ ++      R +G  AK Q VTN 
Sbjct: 2   SVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISL-GSRTRAIGNAAKSQIVTNV 60

Query: 114 NNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAH----GKLYSPSQIGAF 169
            NT +  K+L GR +DDP VQ +   +P+++ +  NG A V+       + ++  Q+   
Sbjct: 61  RNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGM 120

Query: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229
           +L K+KET+EN L     + VI++P++F D++R++   A Q++GLN LR++NE TA ALA
Sbjct: 121 LLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALA 180

Query: 230 YGLDKSE-------DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQAL 282
           YG+ K +        + +   D+G   + + +    KG  +V +T  D +LGG +FD+AL
Sbjct: 181 YGIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEAL 240

Query: 283 LRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHL 342
           + +   EFK +  +++ +++ AL R+ +  EK K  +S++     +LP           +
Sbjct: 241 VDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANAS---DLPLNIECFMNDLDV 297

Query: 343 NMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDL 402
           + K+ RAQFE +   L+ R   P +  M+ A + + DI  + +VGG TR+P V++ +   
Sbjct: 298 SSKMNRAQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKF 357

Query: 403 FGRAPSKAVNPDEAVAIGAAIQGGVL--AGDVTDVLLLDVTPLSLGIETL-----GGVFT 455
           F +  S  +N DEAVA G A+Q  +L  A  V +  + D+ P S+ +        G    
Sbjct: 358 FLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEDGSGEC 417

Query: 456 KLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRG- 514
           ++  +N   P  K   F      + +          E+   +  +G FT+  + P   G 
Sbjct: 418 EVFCKNHPAPFSKVITFHKKEPFELEA---FYTNLHEVPYPDARIGSFTIQNVFPQSDGD 474

Query: 515 VPQIEVTFDIDANGIVHVSA-----KDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYA 569
             +++V   ++ +GI  V++     K    G      +++      ++ +NM    +K  
Sbjct: 475 SSKVKVKVRVNIHGIFSVASASVIEKQNLEGDHSDAPMETETSFKNENKDNM----DKMQ 530

Query: 570 EEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISK 617
            +     ++  A +  E  I  T  K +       +D+ ++L + + K
Sbjct: 531 VDQEEGHQKCHAEHTPEEEIDHTGAKTK----SAVSDKQDRLNQTLKK 574



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 13/102 (12%)

Query: 537 KGTGREQQIVIQSS--GGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTET 594
           KG  +   + IQSS    L +D + + ++N  K   +D+ +KER +A N  E  ++D   
Sbjct: 574 KGKVKSIDLPIQSSLCRQLGQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYD--- 630

Query: 595 KMEEFKDQL-PADECNKLKEEISKMRELLARKDS---ETGEN 632
               F+D+L    E     E++SK+  +L   ++   E GE+
Sbjct: 631 ----FRDRLGTVYEKFITPEDLSKLSAVLEDTENWLYEDGED 668


>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
          Length = 840

 Score =  219 bits (558), Expect = 7e-57
 Identities = 158/573 (27%), Positives = 277/573 (48%), Gaps = 39/573 (6%)

Query: 54  AVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNP 113
           +VVGIDLG  +  VAV      + + N    R TP+ ++F     R +G  AK Q ++N 
Sbjct: 2   SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISF-GPKNRSIGAAAKSQVISNA 60

Query: 114 NNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEA----HGKLYSPSQIGAF 169
            NT    KR  GR + DP V+ +  N+ + IV+   G   ++       + ++  Q+ A 
Sbjct: 61  KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120

Query: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229
           +L K+KETAE+ L     + V++VP ++ D++R++  DA QI+GLN LR++NE TA ALA
Sbjct: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180

Query: 230 YGLDKSE-------DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQAL 282
           YG+ K +        + +   D+G   + +S+    +G  +V +T  DT LGG  FD+ L
Sbjct: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240

Query: 283 LRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHL 342
           + H  +EF ++  +D+     AL R+ +  EK K  +S++     +LP           +
Sbjct: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANAS---DLPLSIECFMNDVDV 297

Query: 343 NMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDL 402
           +  + R +F  +  DL+ R   P +  ++  ++ K DI  V +VGG TR+P V++ +   
Sbjct: 298 SGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKF 357

Query: 403 FGRAPSKAVNPDEAVAIGAAIQGGVL--AGDVTDVLLLDVTPLSLGIE-----TLGGVFT 455
           FG+  S  +N DEAV  G A+Q  +L  A  V +  + DV P  + +        G    
Sbjct: 358 FGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDC 417

Query: 456 KLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRG- 514
           ++ ++N   P  K   F        +         +++   +  + QF++  + P   G 
Sbjct: 418 EVFSKNHAAPFSKVLTFYRKEPFTLEA---YYSSPQDLPYPDPAIAQFSVQKVTPQSDGS 474

Query: 515 VPQIEVTFDIDANGIVHVSAKD-----KGTGREQQIVIQSSGGLSKDDIENMVKNAEKYA 569
             +++V   ++ +GI  VS+       K    E+ +    +   +K++ +  V   E + 
Sbjct: 475 SSKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN---AKEEEKMQVDQEEPHV 531

Query: 570 EEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQ 602
           EE   ++++  A N AE    + ET     KD+
Sbjct: 532 EE---QQQQTPAENKAES--EEMETSQAGSKDK 559


>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
          Length = 999

 Score =  168 bits (425), Expect = 2e-41
 Identities = 120/401 (29%), Positives = 202/401 (50%), Gaps = 32/401 (7%)

Query: 54  AVVGIDLGTTNSCVAVME-GKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTN 112
           AV+ +DLG+ +  VA+++ G   +++ N E  R TP +V    + ER  G  A   A+ N
Sbjct: 34  AVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLK-ENERFFGDSAASMAIKN 92

Query: 113 PNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKL-----YSPSQIG 167
           P  T    + L+G++ D+P V   +    F     +        H ++     +SP ++ 
Sbjct: 93  PKATLRYFQHLLGKQADNPHVA--LYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVL 150

Query: 168 AFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAA 227
             VL   +  AE++     K+AVITVP +FN ++R+A   A +++GL VL++IN+ TA A
Sbjct: 151 GMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATA 210

Query: 228 LAYGLDKSED-----KVIAVYDLGGGTFDISILEIQ---------KGVFEVKSTNGDTFL 273
           L+YG+ + +D     + I  YD+G G+   +I+  Q         +   +++    D  L
Sbjct: 211 LSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTL 270

Query: 274 GGEDFDQALLRHIVKEF----KRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINL 329
           GG + +  L   +   F    K +   D+ ++  A+ ++   A + K  LS++      +
Sbjct: 271 GGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQI 330

Query: 330 PYLTMDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGM 389
             L  D         K+TR +FE +  DL  R   P Q+A+Q AE+S  +I +VILVGG 
Sbjct: 331 EGLMDDVD----FKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGA 386

Query: 390 TRMPKVQQTVQDLFGRAP-SKAVNPDEAVAIGAAIQGGVLA 429
           TR+P+VQ+ +    G+    K +N DEA A+GA  Q   L+
Sbjct: 387 TRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALS 427


>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
          Length = 999

 Score =  168 bits (425), Expect = 2e-41
 Identities = 120/401 (29%), Positives = 202/401 (50%), Gaps = 32/401 (7%)

Query: 54  AVVGIDLGTTNSCVAVME-GKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTN 112
           AV+ +DLG+ +  VA+++ G   +++ N E  R TP +V    + ER  G  A   A+ N
Sbjct: 34  AVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLK-ENERFFGDSAASMAIKN 92

Query: 113 PNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKL-----YSPSQIG 167
           P  T    + L+G++ D+P V   +    F     +        H ++     +SP ++ 
Sbjct: 93  PKATLRYFQHLLGKQADNPHVA--LYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVL 150

Query: 168 AFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAA 227
             VL   +  AE++     K+AVITVP +FN ++R+A   A +++GL VL++IN+ TA A
Sbjct: 151 GMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATA 210

Query: 228 LAYGLDKSED-----KVIAVYDLGGGTFDISILEIQ---------KGVFEVKSTNGDTFL 273
           L+YG+ + +D     + I  YD+G G+   +I+  Q         +   +++    D  L
Sbjct: 211 LSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTL 270

Query: 274 GGEDFDQALLRHIVKEF----KRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINL 329
           GG + +  L   +   F    K +   D+ ++  A+ ++   A + K  LS++      +
Sbjct: 271 GGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQI 330

Query: 330 PYLTMDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGM 389
             L  D         K+TR +FE +  DL  R   P Q+A+Q AE+S  +I +VILVGG 
Sbjct: 331 EGLMDDVD----FKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGA 386

Query: 390 TRMPKVQQTVQDLFGRAP-SKAVNPDEAVAIGAAIQGGVLA 429
           TR+P+VQ+ +    G+    K +N DEA A+GA  Q   L+
Sbjct: 387 TRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALS 427


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 42/170 (24%), Positives = 75/170 (44%), Gaps = 12/170 (7%)

Query: 510 PAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYA 569
           P P G  +I +  D  A+     S+K++    E     ++    S D+  N  +N E+  
Sbjct: 147 PTPDGSERIGLEVDRRASRSSQ-SSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGV 205

Query: 570 EEDRRKKERVEA-VNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSE 628
           EED  + E VE      E +  D E + EE +++   +E    +EE    ++   +K+  
Sbjct: 206 EEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE----EEEEEYEQDERDQKEEG 261

Query: 629 TGENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEK 678
              + R  AS     S+   +       S R GSG+ G+ E+K+++K  +
Sbjct: 262 NDYDTRSEASDSGSESVSFTD------GSVRSGSGTDGSDEKKKERKRAR 305


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 42/170 (24%), Positives = 75/170 (44%), Gaps = 12/170 (7%)

Query: 510 PAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYA 569
           P P G  +I +  D  A+     S+K++    E     ++    S D+  N  +N E+  
Sbjct: 147 PTPDGSERIGLEVDRRASRSSQ-SSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGV 205

Query: 570 EEDRRKKERVEA-VNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSE 628
           EED  + E VE      E +  D E + EE +++   +E    +EE    ++   +K+  
Sbjct: 206 EEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE----EEEEEYEQDERDQKEEG 261

Query: 629 TGENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEK 678
              + R  AS     S+   +       S R GSG+ G+ E+K+++K  +
Sbjct: 262 NDYDTRSEASDSGSESVSFTD------GSVRSGSGTDGSDEKKKERKRAR 305


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 32/121 (26%), Positives = 58/121 (47%), Gaps = 10/121 (8%)

Query: 559 ENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKM 618
           E + +  EK  E+++ +K+  E V   E  +HD E K+ E ++++   E  K++E+  K+
Sbjct: 475 EEIWRQKEKMHEQEKIRKQE-EKVWRQEEKMHDQEEKIREQEEKMWRQE-EKIREQEEKI 532

Query: 619 RELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEK 678
           RE          E IR+    +Q+   K+ E   K    E+         EQ+E  +E+K
Sbjct: 533 RE--------QEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK 584

Query: 679 Q 679
           +
Sbjct: 585 E 585



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 33/126 (26%), Positives = 61/126 (48%), Gaps = 12/126 (9%)

Query: 559 ENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKM 618
           E + +  EK  E++ + +E+ E +   E  + + E KM+E +     +E  K++E+  K+
Sbjct: 523 EKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEE--KIREQEEKI 580

Query: 619 RELLAR------KDSETGENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKE 672
           RE   +      K  E  E IR+    +Q+   K++E   +KM  + E        E+K 
Sbjct: 581 REQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE-EKMCEQEEKMQEQ---EEKM 636

Query: 673 DQKEEK 678
            ++EEK
Sbjct: 637 RRQEEK 642


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
            sapiens]
          Length = 2168

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 9/132 (6%)

Query: 553  LSKDDIENMVKNAEKY-----AEEDRRKKERVEAVNMAEGIIHDTETKME-EFKDQLPAD 606
            L K +   + K A+K      AEE R++KE+++ +   E I    + +ME E + Q   +
Sbjct: 907  LQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILE 966

Query: 607  ECNKLKEEISKMRELLARKDSETGENIRQAASSL---QQASLKLFEMAYKKMASEREGSG 663
               K KEE +  + L A K  +  E  RQ A  L   ++   +   M  K M + ++   
Sbjct: 967  AKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEE 1026

Query: 664  SSGTGEQKEDQK 675
                 ++K D+K
Sbjct: 1027 KERLKQEKRDEK 1038


>gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo
           sapiens]
          Length = 529

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 21/156 (13%)

Query: 523 DIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAV 582
           D D    V V  K KG     + V++   G ++D+++   K  +K+   + RKKE ++  
Sbjct: 252 DYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQ-- 309

Query: 583 NMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQ 642
                        + + K Q   +E  KLKE+      L   K  +      Q     Q+
Sbjct: 310 -------------IWKTKKQQKREEIFKLKEKADNTPVLFHNKQED-----NQKQKEEQR 351

Query: 643 ASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEK 678
              KL   A+KK  S  E S    +  ++E++KE+K
Sbjct: 352 KKQKLAVEAWKKQKS-IEMSMKCASQLKEEEEKEKK 386


>gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo
           sapiens]
          Length = 446

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 21/156 (13%)

Query: 523 DIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAV 582
           D D    V V  K KG     + V++   G ++D+++   K  +K+   + RKKE ++  
Sbjct: 169 DYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQ-- 226

Query: 583 NMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQ 642
                        + + K Q   +E  KLKE+      L   K  +      Q     Q+
Sbjct: 227 -------------IWKTKKQQKREEIFKLKEKADNTPVLFHNKQED-----NQKQKEEQR 268

Query: 643 ASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEK 678
              KL   A+KK  S  E S    +  ++E++KE+K
Sbjct: 269 KKQKLAVEAWKKQKS-IEMSMKCASQLKEEEEKEKK 303


>gi|34577114 cytomatrix protein p110 [Homo sapiens]
          Length = 957

 Score = 37.7 bits (86), Expect = 0.035
 Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 13/118 (11%)

Query: 549 SSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPA--- 605
           +S GL +D   + +K+ E   E+ + +  ++EA       I D      EF DQ+     
Sbjct: 654 ASAGLKRD---SKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDK 710

Query: 606 ------DECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMAS 657
                 DEC K + E+ ++ E+L   ++E  +  ++ A  L+  +L+  +   KK+A+
Sbjct: 711 EASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIA-ELESLTLRHMKDQNKKVAN 767


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 37.0 bits (84), Expect = 0.060
 Identities = 26/99 (26%), Positives = 51/99 (51%), Gaps = 10/99 (10%)

Query: 532 VSAKDKGTG--REQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGII 589
           +S+ ++G     E+  +++S+G LS ++ E  +K  E Y    +  K +VE +      +
Sbjct: 391 ISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEE---L 447

Query: 590 HDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSE 628
              E + EE K +        L+ EI ++++ L+RKD+E
Sbjct: 448 SSKEAQWEELKKKAAG-----LQAEIGQVKQELSRKDTE 481


>gi|118498362 kinectin 1 isoform b [Homo sapiens]
          Length = 1306

 Score = 36.6 bits (83), Expect = 0.078
 Identities = 30/124 (24%), Positives = 63/124 (50%), Gaps = 13/124 (10%)

Query: 533 SAKDKGTGREQQIV-IQSSGGLSKDDIENM--VKNAEKYAEEDRRKKERVEAVN------ 583
           S +D+ T +E+++  IQ+   L K +++ +  + N +  A  +  K ++   V       
Sbjct: 625 SERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRL 684

Query: 584 MAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQA 643
           + E + H+   KMEEFK  +  D+   LK E+ K++ L++ + ++  + + Q    +Q+ 
Sbjct: 685 LEEQLQHEISNKMEEFK--ILNDQNKALKSEVQKLQTLVSEQPNK--DVVEQMEKCIQEK 740

Query: 644 SLKL 647
             KL
Sbjct: 741 DEKL 744


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 36.6 bits (83), Expect = 0.078
 Identities = 30/124 (24%), Positives = 63/124 (50%), Gaps = 13/124 (10%)

Query: 533 SAKDKGTGREQQIV-IQSSGGLSKDDIENM--VKNAEKYAEEDRRKKERVEAVN------ 583
           S +D+ T +E+++  IQ+   L K +++ +  + N +  A  +  K ++   V       
Sbjct: 625 SERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRL 684

Query: 584 MAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQA 643
           + E + H+   KMEEFK  +  D+   LK E+ K++ L++ + ++  + + Q    +Q+ 
Sbjct: 685 LEEQLQHEISNKMEEFK--ILNDQNKALKSEVQKLQTLVSEQPNK--DVVEQMEKCIQEK 740

Query: 644 SLKL 647
             KL
Sbjct: 741 DEKL 744


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 36.6 bits (83), Expect = 0.078
 Identities = 30/124 (24%), Positives = 63/124 (50%), Gaps = 13/124 (10%)

Query: 533 SAKDKGTGREQQIV-IQSSGGLSKDDIENM--VKNAEKYAEEDRRKKERVEAVN------ 583
           S +D+ T +E+++  IQ+   L K +++ +  + N +  A  +  K ++   V       
Sbjct: 625 SERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRL 684

Query: 584 MAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQA 643
           + E + H+   KMEEFK  +  D+   LK E+ K++ L++ + ++  + + Q    +Q+ 
Sbjct: 685 LEEQLQHEISNKMEEFK--ILNDQNKALKSEVQKLQTLVSEQPNK--DVVEQMEKCIQEK 740

Query: 644 SLKL 647
             KL
Sbjct: 741 DEKL 744


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 36.6 bits (83), Expect = 0.078
 Identities = 30/124 (24%), Positives = 63/124 (50%), Gaps = 13/124 (10%)

Query: 533 SAKDKGTGREQQIV-IQSSGGLSKDDIENM--VKNAEKYAEEDRRKKERVEAVN------ 583
           S +D+ T +E+++  IQ+   L K +++ +  + N +  A  +  K ++   V       
Sbjct: 625 SERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRL 684

Query: 584 MAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQA 643
           + E + H+   KMEEFK  +  D+   LK E+ K++ L++ + ++  + + Q    +Q+ 
Sbjct: 685 LEEQLQHEISNKMEEFK--ILNDQNKALKSEVQKLQTLVSEQPNK--DVVEQMEKCIQEK 740

Query: 644 SLKL 647
             KL
Sbjct: 741 DEKL 744


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 36.6 bits (83), Expect = 0.078
 Identities = 37/142 (26%), Positives = 62/142 (43%), Gaps = 10/142 (7%)

Query: 541 REQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFK 600
           REQ+  +       +D  + M    E+  E+D R +E+ E +   + +    E   EE K
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKK 541

Query: 601 DQLPA----DECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMA 656
            Q       D+  K++EE  +MRE   +K  E  E +R+    +Q+   K+ E   K   
Sbjct: 542 TQEQEKKTWDQEEKMREE-ERMRE-REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599

Query: 657 SEREGSGSSGTGEQKEDQKEEK 678
            E +        E+K  ++EEK
Sbjct: 600 QEEKMQEQ----EEKMWEQEEK 617



 Score = 33.5 bits (75), Expect = 0.66
 Identities = 32/138 (23%), Positives = 59/138 (42%), Gaps = 19/138 (13%)

Query: 559 ENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKM 618
           E    + E+   E+ R +ER + +   E ++ + E KM+E ++++   E  K+ E+  KM
Sbjct: 546 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKM 604

Query: 619 RELLAR---------------KDSETGENIRQAASSLQQASLKLFEMAYKKMASE---RE 660
           +E   +               K  E  E + +    +Q+   K++E   K    E   RE
Sbjct: 605 QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 664

Query: 661 GSGSSGTGEQKEDQKEEK 678
                   E+K  ++EEK
Sbjct: 665 QEEKMQGQEEKMREQEEK 682


>gi|32171186 B-cell receptor-associated protein 31 isoform b [Homo
           sapiens]
          Length = 246

 Score = 36.6 bits (83), Expect = 0.078
 Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 2/86 (2%)

Query: 543 QQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQ 602
           QQ  + +S    K   E+  + A+KY EE+ + K+   AV+  +  + + E K+EE    
Sbjct: 125 QQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGA-AVDGGKLDVGNAEVKLEEENRS 183

Query: 603 LPADECNKLKEEISKMRELLARKDSE 628
           L AD   KLK+E++  ++ L + +++
Sbjct: 184 LKAD-LQKLKDELASTKQKLEKAENQ 208


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,863,775
Number of Sequences: 37866
Number of extensions: 973630
Number of successful extensions: 3332
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 149
Number of HSP's that attempted gapping in prelim test: 3046
Number of HSP's gapped (non-prelim): 350
length of query: 679
length of database: 18,247,518
effective HSP length: 109
effective length of query: 570
effective length of database: 14,120,124
effective search space: 8048470680
effective search space used: 8048470680
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.