BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] (679 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] 1318 0.0 gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] 598 e-171 gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens] 576 e-164 gi|13676857 heat shock 70kDa protein 2 [Homo sapiens] 573 e-163 gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens] 568 e-162 gi|167466173 heat shock 70kDa protein 1B [Homo sapiens] 567 e-161 gi|194248072 heat shock 70kDa protein 1A [Homo sapiens] 567 e-161 gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens] 562 e-160 gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens] 479 e-135 gi|48928056 heat shock protein 70kDa family member 13 precursor ... 244 2e-64 gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens] 243 6e-64 gi|42544159 heat shock 105kD [Homo sapiens] 238 1e-62 gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens] 226 4e-59 gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] 219 7e-57 gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens] 168 2e-41 gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens] 168 2e-41 gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 42 0.002 gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 42 0.002 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 41 0.003 gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 39 0.016 gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo sa... 39 0.016 gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo s... 39 0.016 gi|34577114 cytomatrix protein p110 [Homo sapiens] 38 0.035 gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 37 0.060 gi|118498362 kinectin 1 isoform b [Homo sapiens] 37 0.078 gi|118498356 kinectin 1 isoform a [Homo sapiens] 37 0.078 gi|118498368 kinectin 1 isoform c [Homo sapiens] 37 0.078 gi|33620775 kinectin 1 isoform a [Homo sapiens] 37 0.078 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 37 0.078 gi|32171186 B-cell receptor-associated protein 31 isoform b [Hom... 37 0.078 >gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] Length = 679 Score = 1318 bits (3410), Expect = 0.0 Identities = 679/679 (100%), Positives = 679/679 (100%) Query: 1 MISASRAAAARLVGAAASRGPTAARHQDSWNGLSHEAFRLVSRRDYASEAIKGAVVGIDL 60 MISASRAAAARLVGAAASRGPTAARHQDSWNGLSHEAFRLVSRRDYASEAIKGAVVGIDL Sbjct: 1 MISASRAAAARLVGAAASRGPTAARHQDSWNGLSHEAFRLVSRRDYASEAIKGAVVGIDL 60 Query: 61 GTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYAT 120 GTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYAT Sbjct: 61 GTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYAT 120 Query: 121 KRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAEN 180 KRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAEN Sbjct: 121 KRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAEN 180 Query: 181 YLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVI 240 YLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVI Sbjct: 181 YLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVI 240 Query: 241 AVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTK 300 AVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTK Sbjct: 241 AVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTK 300 Query: 301 DNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKLTRAQFEGIVTDLIR 360 DNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKLTRAQFEGIVTDLIR Sbjct: 301 DNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKLTRAQFEGIVTDLIR 360 Query: 361 RTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIG 420 RTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIG Sbjct: 361 RTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIG 420 Query: 421 AAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQT 480 AAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQT Sbjct: 421 AAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQT 480 Query: 481 QVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTG 540 QVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTG Sbjct: 481 QVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTG 540 Query: 541 REQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFK 600 REQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFK Sbjct: 541 REQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFK 600 Query: 601 DQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASERE 660 DQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASERE Sbjct: 601 DQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASERE 660 Query: 661 GSGSSGTGEQKEDQKEEKQ 679 GSGSSGTGEQKEDQKEEKQ Sbjct: 661 GSGSSGTGEQKEDQKEEKQ 679 >gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] Length = 654 Score = 598 bits (1543), Expect = e-171 Identities = 330/635 (51%), Positives = 436/635 (68%), Gaps = 19/635 (2%) Query: 53 GAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTN 112 G VVGIDLGTT SCV V + + +++ N +G R TPS VAFT +GERL+G AK Q +N Sbjct: 28 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87 Query: 113 PNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIV-RASNGDAWVEAHG---KLYSPSQIGA 168 P NT + KRLIGR ++DP VQ+DIK +PFK+V + + V+ G K ++P +I A Sbjct: 88 PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISA 147 Query: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228 VL KMKETAE YLG +AV+TVPAYFND+QRQATKDAG I+GLNV+R+INEPTAAA+ Sbjct: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207 Query: 229 AYGLDKSE-DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIV 287 AYGLDK E +K I V+DLGGGTFD+S+L I GVFEV +TNGDT LGGEDFDQ ++ H + Sbjct: 208 AYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFI 267 Query: 288 KEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKLT 347 K +K++TG D+ KDN A+Q++R EKAK LSS Q I + + LT Sbjct: 268 KLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGED----FSETLT 323 Query: 348 RAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF-GRA 406 RA+FE + DL R T+ P QK ++D+++ KSDI E++LVGG TR+PK+QQ V++ F G+ Sbjct: 324 RAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKE 383 Query: 407 PSKAVNPDEAVAIGAAIQGGVLAGD--VTDVLLLDVTPLSLGIETLGGVFTKLINRNTTI 464 PS+ +NPDEAVA GAA+Q GVL+GD D++LLDV PL+LGIET+GGV TKLI RNT + Sbjct: 384 PSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVV 443 Query: 465 PTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDI 524 PTKKSQ+FSTA+D Q V IKV +GER + DN LLG F L GIPPAPRGVPQIEVTF+I Sbjct: 444 PTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEI 503 Query: 525 DANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVN 583 D NGI+ V+A+DKGTG + +I I L+ ++IE MV +AEK+AEED++ KER++ N Sbjct: 504 DVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRN 563 Query: 584 MAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQA 643 E + + ++ + K++L KL E + E + E E+ + A +A Sbjct: 564 ELESYAYSLKNQIGD-KEKLG----GKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKA 618 Query: 644 SLKLFEMAYKKMASEREGS-GSSGTGEQKEDQKEE 677 K E + + S+ GS G TGE+ +K+E Sbjct: 619 KKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKDE 653 >gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens] Length = 646 Score = 576 bits (1484), Expect = e-164 Identities = 315/615 (51%), Positives = 418/615 (67%), Gaps = 18/615 (2%) Query: 52 KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111 KG VGIDLGTT SCV V + + +++ N +G RTTPS VAFT D ERL+G AK Q Sbjct: 3 KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 61 Query: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVR-ASNGDAWVEAHG--KLYSPSQIGA 168 NP NT + KRLIGRR+DD VQ D+K+ PF +V A VE G K + P ++ + Sbjct: 62 NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121 Query: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228 VL KMKE AE YLG T NAV+TVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAAA+ Sbjct: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181 Query: 229 AYGLDKS--EDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHI 286 AYGLDK ++ + ++DLGGGTFD+SIL I+ G+FEVKST GDT LGGEDFD ++ H Sbjct: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241 Query: 287 VKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKL 346 + EFKR+ D++++ A++R+R A E+AK LSSS Q I + L + Sbjct: 242 IAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGID----FYTSI 297 Query: 347 TRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF-GR 405 TRA+FE + DL R T+ P +KA++DA++ KS I +++LVGG TR+PK+Q+ +QD F G+ Sbjct: 298 TRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGK 357 Query: 406 APSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLINRN 461 +K++NPDEAVA GAA+Q +L+GD V D+LLLDVTPLSLGIET GGV T LI RN Sbjct: 358 ELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRN 417 Query: 462 TTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVT 521 TTIPTK++Q F+T +D Q V I+V +GER M DN LLG+F L GIPPAPRGVPQIEVT Sbjct: 418 TTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVT 477 Query: 522 FDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKERVE 580 FDIDANGI++VSA DK TG+E +I I G LSK+DIE MV+ AEKY ED +++++V Sbjct: 478 FDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVS 537 Query: 581 AVNMAEGIIHDTETKMEEFKDQ--LPADECNKLKEEISKMRELLARKDSETGENIRQAAS 638 + N E + + +E+ K Q + ++ K+ ++ +++ L + + E Sbjct: 538 SKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQK 597 Query: 639 SLQQASLKLFEMAYK 653 L++ + Y+ Sbjct: 598 ELEKVCNPIITKLYQ 612 >gi|13676857 heat shock 70kDa protein 2 [Homo sapiens] Length = 639 Score = 573 bits (1476), Expect = e-163 Identities = 313/630 (49%), Positives = 416/630 (66%), Gaps = 20/630 (3%) Query: 52 KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111 +G +GIDLGTT SCV V + + +++ N +G RTTPS VAFT D ERL+G AK Q Sbjct: 4 RGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 62 Query: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIV-RASNGDAWVEAHG--KLYSPSQIGA 168 NP NT + KRLIGR+++D VQ D+K+ PF++V VE G K + P +I + Sbjct: 63 NPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISS 122 Query: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228 VL KMKE AE YLG +AVITVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAAA+ Sbjct: 123 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182 Query: 229 AYGLDKSE----DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLR 284 AYGLDK +K + ++DLGGGTFD+SIL I+ G+FEVKST GDT LGGEDFD ++ Sbjct: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVS 242 Query: 285 HIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNM 344 H+ +EFKR+ D+ + A++R+R A E+AK LSSS Q I + L Sbjct: 243 HLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVD----FYT 298 Query: 345 KLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF- 403 +TRA+FE + DL R T+ P +KA++DA++ K I E++LVGG TR+PK+Q+ +QD F Sbjct: 299 SITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFN 358 Query: 404 GRAPSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLIN 459 G+ +K++NPDEAVA GAA+Q +L GD V D+LLLDVTPLSLGIET GGV T LI Sbjct: 359 GKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIK 418 Query: 460 RNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIE 519 RNTTIPTK++Q F+T +D Q+ V ++V +GER M DN LLG+F L GIPPAPRGVPQIE Sbjct: 419 RNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIE 478 Query: 520 VTFDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKER 578 VTFDIDANGI++V+A DK TG+E +I I G LSKDDI+ MV+ AE+Y ED ++R Sbjct: 479 VTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDR 538 Query: 579 VEAVNMAEGIIHDTETKMEE--FKDQLPADECNKLKEEISKMRELLARKDSETGENIRQA 636 V A N E ++ + +E+ + ++ + NK+ ++ ++ L R + Sbjct: 539 VAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHK 598 Query: 637 ASSLQQASLKLFEMAYKKMASEREGSGSSG 666 L++ + Y+ G G SG Sbjct: 599 QKELERVCNPIISKLYQGGPGGGSGGGGSG 628 >gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens] Length = 643 Score = 568 bits (1464), Expect = e-162 Identities = 317/639 (49%), Positives = 423/639 (66%), Gaps = 22/639 (3%) Query: 49 EAIKGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQ 108 +A + VGIDLGTT SCV V + + ++L N +G RTTPS VAFT D ERLVG AK Q Sbjct: 2 QAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFT-DTERLVGDAAKSQ 60 Query: 109 AVTNPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEA----HGKLYSPS 164 A NP+NT + KRLIGR++ D VQ D+K+ PF++V + G V K + P Sbjct: 61 AALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVV-SEGGKPKVRVCYRGEDKTFYPE 119 Query: 165 QIGAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPT 224 +I + VL KMKETAE YLG K+AVITVPAYFNDSQRQATKDAG I+GLNVLR+INEPT Sbjct: 120 EISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPT 179 Query: 225 AAALAYGLDK--SEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQAL 282 AAA+AYGLD+ + ++ + ++DLGGGTFD+S+L I GVFEVK+T GDT LGGEDFD L Sbjct: 180 AAAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRL 239 Query: 283 LRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHL 342 + H ++EF+R+ G DL+ + AL+R+R A E+AK LSSS Q + + L Sbjct: 240 VNHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVD----F 295 Query: 343 NMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDL 402 +TRA+FE + +DL R T+ P +KA++DA++ K+ I +V+LVGG TR+PKVQ+ +QD Sbjct: 296 YTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDF 355 Query: 403 F-GRAPSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKL 457 F G+ +K++NPDEAVA GAA+Q VL GD V D+LLLDV PLSLG+ET GGV T L Sbjct: 356 FNGKELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTL 415 Query: 458 INRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQ 517 I RN TIPTK++Q F+T +D Q V I+V +GER M DN LLG+F L GIPPAPRGVPQ Sbjct: 416 IQRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQ 475 Query: 518 IEVTFDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKK 576 IEVTFDIDANGI+ V+A D+ TG+ +I I G LSK+++E MV AE+Y ED ++ Sbjct: 476 IEVTFDIDANGILSVTATDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDEAQR 535 Query: 577 ERVEAVNMAEGIIHDTETKMEE--FKDQLPADECNKLKEEISKMRELLARKDSETGENIR 634 +RV A N E + + ++E +D++P ++ K++++ ++ L E Sbjct: 536 DRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVLAWLEHNQLAEKEEYE 595 Query: 635 QAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKED 673 L+Q +F Y G S GT ++ D Sbjct: 596 HQKRELEQICRPIFSRLYG--GPGVPGGSSCGTQARQGD 632 >gi|167466173 heat shock 70kDa protein 1B [Homo sapiens] Length = 641 Score = 567 bits (1462), Expect = e-161 Identities = 315/633 (49%), Positives = 426/633 (67%), Gaps = 31/633 (4%) Query: 52 KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111 K A +GIDLGTT SCV V + + +++ N +G RTTPS VAFT D ERL+G AK Q Sbjct: 3 KAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAL 61 Query: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGD-----AWVEAHGKLYSPSQI 166 NP NT + KRLIGR++ DP VQ D+K+ PF+++ ++GD + K + P +I Sbjct: 62 NPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVI--NDGDKPKVQVSYKGETKAFYPEEI 119 Query: 167 GAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAA 226 + VL KMKE AE YLG+ NAVITVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAA Sbjct: 120 SSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAA 179 Query: 227 ALAYGLDKSE--DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLR 284 A+AYGLD++ ++ + ++DLGGGTFD+SIL I G+FEVK+T GDT LGGEDFD L+ Sbjct: 180 AIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVN 239 Query: 285 HIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNM 344 H V+EFKR+ D++++ A++R+R A E+AK LSSS Q + + L Sbjct: 240 HFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGID----FYT 295 Query: 345 KLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF- 403 +TRA+FE + +DL R T+ P +KA++DA++ K+ I +++LVGG TR+PKVQ+ +QD F Sbjct: 296 SITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFN 355 Query: 404 GRAPSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLIN 459 GR +K++NPDEAVA GAA+Q +L GD V D+LLLDV PLSLG+ET GGV T LI Sbjct: 356 GRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIK 415 Query: 460 RNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIE 519 RN+TIPTK++Q+F+T +D Q V I+V +GER M DN LLG+F L GIPPAPRGVPQIE Sbjct: 416 RNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIE 475 Query: 520 VTFDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKER 578 VTFDIDANGI++V+A DK TG+ +I I G LSK++IE MV+ AEKY ED ++ER Sbjct: 476 VTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRER 535 Query: 579 VEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSET---GENIRQ 635 V A N E + ++ +E+ + E +K K+ + K +E+++ D+ T + Sbjct: 536 VSAKNALESYAFNMKSAVEDEGLKGKISEADK-KKVLDKCQEVISWLDANTLAEKDEFEH 594 Query: 636 AASSLQQASLKLFEMAYKKMASEREGSGSSGTG 668 L+Q + Y +G+G G G Sbjct: 595 KRKELEQVCNPIISGLY-------QGAGGPGPG 620 >gi|194248072 heat shock 70kDa protein 1A [Homo sapiens] Length = 641 Score = 567 bits (1462), Expect = e-161 Identities = 315/633 (49%), Positives = 426/633 (67%), Gaps = 31/633 (4%) Query: 52 KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111 K A +GIDLGTT SCV V + + +++ N +G RTTPS VAFT D ERL+G AK Q Sbjct: 3 KAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAL 61 Query: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGD-----AWVEAHGKLYSPSQI 166 NP NT + KRLIGR++ DP VQ D+K+ PF+++ ++GD + K + P +I Sbjct: 62 NPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVI--NDGDKPKVQVSYKGETKAFYPEEI 119 Query: 167 GAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAA 226 + VL KMKE AE YLG+ NAVITVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAA Sbjct: 120 SSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAA 179 Query: 227 ALAYGLDKSE--DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLR 284 A+AYGLD++ ++ + ++DLGGGTFD+SIL I G+FEVK+T GDT LGGEDFD L+ Sbjct: 180 AIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVN 239 Query: 285 HIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNM 344 H V+EFKR+ D++++ A++R+R A E+AK LSSS Q + + L Sbjct: 240 HFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGID----FYT 295 Query: 345 KLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF- 403 +TRA+FE + +DL R T+ P +KA++DA++ K+ I +++LVGG TR+PKVQ+ +QD F Sbjct: 296 SITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFN 355 Query: 404 GRAPSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLIN 459 GR +K++NPDEAVA GAA+Q +L GD V D+LLLDV PLSLG+ET GGV T LI Sbjct: 356 GRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIK 415 Query: 460 RNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIE 519 RN+TIPTK++Q+F+T +D Q V I+V +GER M DN LLG+F L GIPPAPRGVPQIE Sbjct: 416 RNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIE 475 Query: 520 VTFDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKER 578 VTFDIDANGI++V+A DK TG+ +I I G LSK++IE MV+ AEKY ED ++ER Sbjct: 476 VTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRER 535 Query: 579 VEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSET---GENIRQ 635 V A N E + ++ +E+ + E +K K+ + K +E+++ D+ T + Sbjct: 536 VSAKNALESYAFNMKSAVEDEGLKGKISEADK-KKVLDKCQEVISWLDANTLAEKDEFEH 594 Query: 636 AASSLQQASLKLFEMAYKKMASEREGSGSSGTG 668 L+Q + Y +G+G G G Sbjct: 595 KRKELEQVCNPIISGLY-------QGAGGPGPG 620 >gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens] Length = 641 Score = 562 bits (1449), Expect = e-160 Identities = 305/585 (52%), Positives = 408/585 (69%), Gaps = 21/585 (3%) Query: 52 KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111 KG +GIDLGTT SCV V + + +++ N +G RTTPS VAFT D ERL+G AK Q Sbjct: 5 KGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 63 Query: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAH---GKLYSPSQIGA 168 NP NT + KRLIGR+++DP VQ D+K PF+++ + ++ K + P +I + Sbjct: 64 NPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISS 123 Query: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228 VL K+KETAE +LGH NAVITVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAAA+ Sbjct: 124 MVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 183 Query: 229 AYGLDKSE--DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHI 286 AYGLDK ++ + ++DLGGGTFD+SIL I G+FEVK+T GDT LGGEDFD L+ H Sbjct: 184 AYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHF 243 Query: 287 VKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKL 346 V+EFKR+ D++++ A++R+R A E+AK LSSS Q ++ + L + Sbjct: 244 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGID----FYTSI 299 Query: 347 TRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF-GR 405 TRA+FE + DL R T+ P +KA++DA++ K+ I +++LVGG TR+PKVQ+ +QD F GR Sbjct: 300 TRARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGR 359 Query: 406 APSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLINRN 461 +K++NPDEAVA GAA+Q +L GD V D+LLLDV PLSLG+ET GGV T LI RN Sbjct: 360 DLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRN 419 Query: 462 TTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVT 521 +TIPTK++Q+F+T +D Q V I+V +GER M DN LLG+F L GIPPAPRGVPQIEVT Sbjct: 420 STIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVT 479 Query: 522 FDIDANGIVHVSAKDKGTGREQQIVI-QSSGGLSKDDIENMVKNAEKYAEEDRRKKERVE 580 FDIDANGI++V+A DK TG+ +I I G LSK++IE MV +AEKY ED ++E++ Sbjct: 480 FDIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIA 539 Query: 581 AVNMAEGIIHDTETKM--EEFKDQLPADECNKLKEEISKMRELLA 623 A N E + ++ + E K ++ + NK+ + K ELL+ Sbjct: 540 AKNALESYAFNMKSVVSDEGLKGKISESDKNKI---LDKCNELLS 581 >gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens] Length = 493 Score = 479 bits (1234), Expect = e-135 Identities = 261/476 (54%), Positives = 334/476 (70%), Gaps = 16/476 (3%) Query: 52 KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111 KG VGIDLGTT SCV V + + +++ N +G RTTPS VAFT D ERL+G AK Q Sbjct: 3 KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 61 Query: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVR-ASNGDAWVEAHG--KLYSPSQIGA 168 NP NT + KRLIGRR+DD VQ D+K+ PF +V A VE G K + P ++ + Sbjct: 62 NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121 Query: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228 VL KMKE AE YLG T NAV+TVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAAA+ Sbjct: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181 Query: 229 AYGLDK--SEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHI 286 AYGLDK ++ + ++DLGGGTFD+SIL I+ G+FEVKST GDT LGGEDFD ++ H Sbjct: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241 Query: 287 VKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKL 346 + EFKR+ D++++ A++R+R A E+AK LSSS Q I + L + Sbjct: 242 IAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGID----FYTSI 297 Query: 347 TRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF-GR 405 TRA+FE + DL R T+ P +KA++DA++ KS I +++LVGG TR+PK+Q+ +QD F G+ Sbjct: 298 TRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGK 357 Query: 406 APSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLINRN 461 +K++NPDEAVA GAA+Q +L+GD V D+LLLDVTPLSLGIET GGV T LI RN Sbjct: 358 ELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRN 417 Query: 462 TTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPA-PRGVP 516 TTIPTK++Q F+T +D Q V I+V +GER M DN LLG+F L G+P P G P Sbjct: 418 TTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473 >gi|48928056 heat shock protein 70kDa family member 13 precursor [Homo sapiens] Length = 471 Score = 244 bits (622), Expect = 2e-64 Identities = 150/420 (35%), Positives = 236/420 (56%), Gaps = 47/420 (11%) Query: 55 VVGIDLGTTNSCVAVM---EGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111 V+GIDLGTT V V GK KV+ + G + PS+V+FT D + VG + A + Sbjct: 33 VIGIDLGTTYCSVGVFFPGTGK-VKVIPDENGHISIPSMVSFT-DNDVYVGYESVELADS 90 Query: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKLY--SPSQIGAF 169 NP NT Y KR IG+ + E++ +I PFK++ + + + SP +G+ Sbjct: 91 NPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVTSNETITVSPEYVGSR 150 Query: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229 +L+K+KE AE YLG NAVI+VPA F+ QR +T +A ++GL +LRVINEPTAAA+A Sbjct: 151 LLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMA 210 Query: 230 YGLDKSEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKE 289 YGL K++ + V DLGGGT D+S+L Q G+F ++ +G+ LGG+DF+Q LL+++ K+ Sbjct: 211 YGLHKADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQ 270 Query: 290 FKRETGVDLTKDNMALQRVREAAEKAKCELS--SSVQ-----------------TDINLP 330 + G ++ + R+R+A E K L+ S Q +D LP Sbjct: 271 IYQTYGFVPSRKE-EIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELP 329 Query: 331 YLTMDSSGPKHLNM--------------------KLTRAQFEGIVTDLIRRTIAPCQKAM 370 + S+ +N +++R F+ + DL ++ + P Q+ + Sbjct: 330 KDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVL 389 Query: 371 QDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAG 430 ++ + K++I EV+LVGG TR+P+++Q +Q+ FG+ P+ +V+PD AV G AIQ G+ G Sbjct: 390 KEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAIQAGIDGG 449 >gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens] Length = 509 Score = 243 bits (619), Expect = 6e-64 Identities = 159/512 (31%), Positives = 264/512 (51%), Gaps = 24/512 (4%) Query: 54 AVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNP 113 A +G+ LG T++CVAV + +A V+ N G R TP+VVA++ + E +VG+ AK+ + N Sbjct: 2 AAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYS-ENEEIVGLAAKQSRIRNI 60 Query: 114 NNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEA----HGKLYSPSQIGAF 169 +NT K+++GR DP+ QK I ++ NG E K +P + Sbjct: 61 SNTVMKVKQILGRSSSDPQAQKYIAESKCLVIE-KNGKLRYEIDTGEETKFVNPEDVARL 119 Query: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229 + KMKETA + LG A + VITVP F + Q+ A +A + +G NVLR+I+EP+AA LA Sbjct: 120 IFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLA 179 Query: 230 YGLDKSE---DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHI 286 YG+ + I V+ LGG + +S++E+ G++ V STN D +GG F + L +++ Sbjct: 180 YGIGQDSPTGKSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYL 239 Query: 287 VKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKL 346 EF+R D+ + A+ ++ +AE AK LS+ + L L + + + Sbjct: 240 ASEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEG----QDFDCNV 295 Query: 347 TRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRA 406 +RA+FE + + L + I + + + DI +V+L GG +R+PK+QQ ++DLF Sbjct: 296 SRARFELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAV 355 Query: 407 P-SKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTP---LSLGIETLGGV-FTKL 457 ++ PDE + IGAAI+ G+L G V D L+++ + L G++ G FT L Sbjct: 356 ELLNSIPPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVL 415 Query: 458 INRNTTIPTKKSQVFSTAAD-GQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVP 516 T +P ++ +E+ G+ + K Q L + G+ Sbjct: 416 FPSGTPLPARRQHTLQAPGSISSVCLELYESDGKNSAKEETK-FAQVVLQDLDKKENGLR 474 Query: 517 QIEVTFDIDANGIVHVSAKDKGTGREQQIVIQ 548 I + +G +HV+ D+ TG+ + I I+ Sbjct: 475 DILAVLTMKRDGSLHVTCTDQETGKCEAISIE 506 >gi|42544159 heat shock 105kD [Homo sapiens] Length = 858 Score = 238 bits (607), Expect = 1e-62 Identities = 169/582 (29%), Positives = 287/582 (49%), Gaps = 36/582 (6%) Query: 54 AVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNP 113 +VVG+D+G+ + +AV + + N R TPSV++F + R +G+ AK Q +T+ Sbjct: 2 SVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKN-RTIGVAAKNQQITHA 60 Query: 114 NNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEA----HGKLYSPSQIGAF 169 NNT KR GR ++DP +QK+ +N+ + +V NG ++ L+S QI A Sbjct: 61 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120 Query: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229 +L K+KETAEN L + VI+VP++F D++R++ DA QI GLN LR++N+ TA AL Sbjct: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180 Query: 230 YGLDKSE-------DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQAL 282 YG+ K + +++ D+G F +S KG +V T D FLGG++FD+ L Sbjct: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240 Query: 283 LRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHL 342 + H EFK + +D AL R+ + EK K +L SS TD LP K + Sbjct: 241 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLK-KLMSSNSTD--LPLNIECFMNDKDV 297 Query: 343 NMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDL 402 + K+ R+QFE + +L+++ P ++ + D+ V +VGG TR+P V++ + Sbjct: 298 SGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKF 357 Query: 403 FGRAPSKAVNPDEAVAIGAAIQGGVL--AGDVTDVLLLDVTPLSLGI------ETLGGVF 454 FG+ S +N DEAVA G A+Q +L A V + + D P + + E GV Sbjct: 358 FGKDISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVH 417 Query: 455 TKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRG 514 ++ +RN P K F + + QG + +G+F + + G Sbjct: 418 -EVFSRNHAAPFSKVLTFLRRGPFELEAFYSDPQG---VPYPEAKIGRFVVQNVSAQKDG 473 Query: 515 -VPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDR 573 +++V ++ +GI +S +++ + + S+ D+E + + + + D+ Sbjct: 474 EKSRVKVKVRVNTHGIFTIST----ASMVEKVPTEENEMSSEADMECLNQRPPENPDTDK 529 Query: 574 RKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEI 615 V+ N G +T ++ P+ E + +I Sbjct: 530 ----NVQQDNSEAGTQPQVQTDAQQTSQSPPSPELTSEENKI 567 >gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens] Length = 839 Score = 226 bits (577), Expect = 4e-59 Identities = 161/588 (27%), Positives = 287/588 (48%), Gaps = 39/588 (6%) Query: 54 AVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNP 113 +VVGIDLG N +AV + + N R TP+ ++ R +G AK Q VTN Sbjct: 2 SVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISL-GSRTRAIGNAAKSQIVTNV 60 Query: 114 NNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAH----GKLYSPSQIGAF 169 NT + K+L GR +DDP VQ + +P+++ + NG A V+ + ++ Q+ Sbjct: 61 RNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGM 120 Query: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229 +L K+KET+EN L + VI++P++F D++R++ A Q++GLN LR++NE TA ALA Sbjct: 121 LLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALA 180 Query: 230 YGLDKSE-------DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQAL 282 YG+ K + + + D+G + + + KG +V +T D +LGG +FD+AL Sbjct: 181 YGIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEAL 240 Query: 283 LRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHL 342 + + EFK + +++ +++ AL R+ + EK K +S++ +LP + Sbjct: 241 VDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANAS---DLPLNIECFMNDLDV 297 Query: 343 NMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDL 402 + K+ RAQFE + L+ R P + M+ A + + DI + +VGG TR+P V++ + Sbjct: 298 SSKMNRAQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKF 357 Query: 403 FGRAPSKAVNPDEAVAIGAAIQGGVL--AGDVTDVLLLDVTPLSLGIETL-----GGVFT 455 F + S +N DEAVA G A+Q +L A V + + D+ P S+ + G Sbjct: 358 FLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEDGSGEC 417 Query: 456 KLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRG- 514 ++ +N P K F + + E+ + +G FT+ + P G Sbjct: 418 EVFCKNHPAPFSKVITFHKKEPFELEA---FYTNLHEVPYPDARIGSFTIQNVFPQSDGD 474 Query: 515 VPQIEVTFDIDANGIVHVSA-----KDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYA 569 +++V ++ +GI V++ K G +++ ++ +NM +K Sbjct: 475 SSKVKVKVRVNIHGIFSVASASVIEKQNLEGDHSDAPMETETSFKNENKDNM----DKMQ 530 Query: 570 EEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISK 617 + ++ A + E I T K + +D+ ++L + + K Sbjct: 531 VDQEEGHQKCHAEHTPEEEIDHTGAKTK----SAVSDKQDRLNQTLKK 574 Score = 31.2 bits (69), Expect = 3.3 Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 13/102 (12%) Query: 537 KGTGREQQIVIQSS--GGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTET 594 KG + + IQSS L +D + + ++N K +D+ +KER +A N E ++D Sbjct: 574 KGKVKSIDLPIQSSLCRQLGQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYD--- 630 Query: 595 KMEEFKDQL-PADECNKLKEEISKMRELLARKDS---ETGEN 632 F+D+L E E++SK+ +L ++ E GE+ Sbjct: 631 ----FRDRLGTVYEKFITPEDLSKLSAVLEDTENWLYEDGED 668 >gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] Length = 840 Score = 219 bits (558), Expect = 7e-57 Identities = 158/573 (27%), Positives = 277/573 (48%), Gaps = 39/573 (6%) Query: 54 AVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNP 113 +VVGIDLG + VAV + + N R TP+ ++F R +G AK Q ++N Sbjct: 2 SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISF-GPKNRSIGAAAKSQVISNA 60 Query: 114 NNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEA----HGKLYSPSQIGAF 169 NT KR GR + DP V+ + N+ + IV+ G ++ + ++ Q+ A Sbjct: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120 Query: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229 +L K+KETAE+ L + V++VP ++ D++R++ DA QI+GLN LR++NE TA ALA Sbjct: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180 Query: 230 YGLDKSE-------DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQAL 282 YG+ K + + + D+G + +S+ +G +V +T DT LGG FD+ L Sbjct: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240 Query: 283 LRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHL 342 + H +EF ++ +D+ AL R+ + EK K +S++ +LP + Sbjct: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANAS---DLPLSIECFMNDVDV 297 Query: 343 NMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDL 402 + + R +F + DL+ R P + ++ ++ K DI V +VGG TR+P V++ + Sbjct: 298 SGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKF 357 Query: 403 FGRAPSKAVNPDEAVAIGAAIQGGVL--AGDVTDVLLLDVTPLSLGIE-----TLGGVFT 455 FG+ S +N DEAV G A+Q +L A V + + DV P + + G Sbjct: 358 FGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDC 417 Query: 456 KLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRG- 514 ++ ++N P K F + +++ + + QF++ + P G Sbjct: 418 EVFSKNHAAPFSKVLTFYRKEPFTLEA---YYSSPQDLPYPDPAIAQFSVQKVTPQSDGS 474 Query: 515 VPQIEVTFDIDANGIVHVSAKD-----KGTGREQQIVIQSSGGLSKDDIENMVKNAEKYA 569 +++V ++ +GI VS+ K E+ + + +K++ + V E + Sbjct: 475 SSKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN---AKEEEKMQVDQEEPHV 531 Query: 570 EEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQ 602 EE ++++ A N AE + ET KD+ Sbjct: 532 EE---QQQQTPAENKAES--EEMETSQAGSKDK 559 >gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens] Length = 999 Score = 168 bits (425), Expect = 2e-41 Identities = 120/401 (29%), Positives = 202/401 (50%), Gaps = 32/401 (7%) Query: 54 AVVGIDLGTTNSCVAVME-GKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTN 112 AV+ +DLG+ + VA+++ G +++ N E R TP +V + ER G A A+ N Sbjct: 34 AVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLK-ENERFFGDSAASMAIKN 92 Query: 113 PNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKL-----YSPSQIG 167 P T + L+G++ D+P V + F + H ++ +SP ++ Sbjct: 93 PKATLRYFQHLLGKQADNPHVA--LYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVL 150 Query: 168 AFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAA 227 VL + AE++ K+AVITVP +FN ++R+A A +++GL VL++IN+ TA A Sbjct: 151 GMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATA 210 Query: 228 LAYGLDKSED-----KVIAVYDLGGGTFDISILEIQ---------KGVFEVKSTNGDTFL 273 L+YG+ + +D + I YD+G G+ +I+ Q + +++ D L Sbjct: 211 LSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTL 270 Query: 274 GGEDFDQALLRHIVKEF----KRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINL 329 GG + + L + F K + D+ ++ A+ ++ A + K LS++ + Sbjct: 271 GGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQI 330 Query: 330 PYLTMDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGM 389 L D K+TR +FE + DL R P Q+A+Q AE+S +I +VILVGG Sbjct: 331 EGLMDDVD----FKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGA 386 Query: 390 TRMPKVQQTVQDLFGRAP-SKAVNPDEAVAIGAAIQGGVLA 429 TR+P+VQ+ + G+ K +N DEA A+GA Q L+ Sbjct: 387 TRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALS 427 >gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens] Length = 999 Score = 168 bits (425), Expect = 2e-41 Identities = 120/401 (29%), Positives = 202/401 (50%), Gaps = 32/401 (7%) Query: 54 AVVGIDLGTTNSCVAVME-GKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTN 112 AV+ +DLG+ + VA+++ G +++ N E R TP +V + ER G A A+ N Sbjct: 34 AVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLK-ENERFFGDSAASMAIKN 92 Query: 113 PNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKL-----YSPSQIG 167 P T + L+G++ D+P V + F + H ++ +SP ++ Sbjct: 93 PKATLRYFQHLLGKQADNPHVA--LYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVL 150 Query: 168 AFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAA 227 VL + AE++ K+AVITVP +FN ++R+A A +++GL VL++IN+ TA A Sbjct: 151 GMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATA 210 Query: 228 LAYGLDKSED-----KVIAVYDLGGGTFDISILEIQ---------KGVFEVKSTNGDTFL 273 L+YG+ + +D + I YD+G G+ +I+ Q + +++ D L Sbjct: 211 LSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTL 270 Query: 274 GGEDFDQALLRHIVKEF----KRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINL 329 GG + + L + F K + D+ ++ A+ ++ A + K LS++ + Sbjct: 271 GGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQI 330 Query: 330 PYLTMDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGM 389 L D K+TR +FE + DL R P Q+A+Q AE+S +I +VILVGG Sbjct: 331 EGLMDDVD----FKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGA 386 Query: 390 TRMPKVQQTVQDLFGRAP-SKAVNPDEAVAIGAAIQGGVLA 429 TR+P+VQ+ + G+ K +N DEA A+GA Q L+ Sbjct: 387 TRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALS 427 >gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] Length = 709 Score = 41.6 bits (96), Expect = 0.002 Identities = 42/170 (24%), Positives = 75/170 (44%), Gaps = 12/170 (7%) Query: 510 PAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYA 569 P P G +I + D A+ S+K++ E ++ S D+ N +N E+ Sbjct: 147 PTPDGSERIGLEVDRRASRSSQ-SSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGV 205 Query: 570 EEDRRKKERVEA-VNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSE 628 EED + E VE E + D E + EE +++ +E +EE ++ +K+ Sbjct: 206 EEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE----EEEEEYEQDERDQKEEG 261 Query: 629 TGENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEK 678 + R AS S+ + S R GSG+ G+ E+K+++K + Sbjct: 262 NDYDTRSEASDSGSESVSFTD------GSVRSGSGTDGSDEKKKERKRAR 305 >gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] Length = 727 Score = 41.6 bits (96), Expect = 0.002 Identities = 42/170 (24%), Positives = 75/170 (44%), Gaps = 12/170 (7%) Query: 510 PAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYA 569 P P G +I + D A+ S+K++ E ++ S D+ N +N E+ Sbjct: 147 PTPDGSERIGLEVDRRASRSSQ-SSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGV 205 Query: 570 EEDRRKKERVEA-VNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSE 628 EED + E VE E + D E + EE +++ +E +EE ++ +K+ Sbjct: 206 EEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE----EEEEEYEQDERDQKEEG 261 Query: 629 TGENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEK 678 + R AS S+ + S R GSG+ G+ E+K+++K + Sbjct: 262 NDYDTRSEASDSGSESVSFTD------GSVRSGSGTDGSDEKKKERKRAR 305 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/121 (26%), Positives = 58/121 (47%), Gaps = 10/121 (8%) Query: 559 ENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKM 618 E + + EK E+++ +K+ E V E +HD E K+ E ++++ E K++E+ K+ Sbjct: 475 EEIWRQKEKMHEQEKIRKQE-EKVWRQEEKMHDQEEKIREQEEKMWRQE-EKIREQEEKI 532 Query: 619 RELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEK 678 RE E IR+ +Q+ K+ E K E+ EQ+E +E+K Sbjct: 533 RE--------QEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK 584 Query: 679 Q 679 + Sbjct: 585 E 585 Score = 37.7 bits (86), Expect = 0.035 Identities = 33/126 (26%), Positives = 61/126 (48%), Gaps = 12/126 (9%) Query: 559 ENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKM 618 E + + EK E++ + +E+ E + E + + E KM+E + +E K++E+ K+ Sbjct: 523 EKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEE--KIREQEEKI 580 Query: 619 RELLAR------KDSETGENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKE 672 RE + K E E IR+ +Q+ K++E +KM + E E+K Sbjct: 581 REQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE-EKMCEQEEKMQEQ---EEKM 636 Query: 673 DQKEEK 678 ++EEK Sbjct: 637 RRQEEK 642 >gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo sapiens] Length = 2168 Score = 38.9 bits (89), Expect = 0.016 Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 9/132 (6%) Query: 553 LSKDDIENMVKNAEKY-----AEEDRRKKERVEAVNMAEGIIHDTETKME-EFKDQLPAD 606 L K + + K A+K AEE R++KE+++ + E I + +ME E + Q + Sbjct: 907 LQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILE 966 Query: 607 ECNKLKEEISKMRELLARKDSETGENIRQAASSL---QQASLKLFEMAYKKMASEREGSG 663 K KEE + + L A K + E RQ A L ++ + M K M + ++ Sbjct: 967 AKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEE 1026 Query: 664 SSGTGEQKEDQK 675 ++K D+K Sbjct: 1027 KERLKQEKRDEK 1038 >gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo sapiens] Length = 529 Score = 38.9 bits (89), Expect = 0.016 Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 21/156 (13%) Query: 523 DIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAV 582 D D V V K KG + V++ G ++D+++ K +K+ + RKKE ++ Sbjct: 252 DYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQ-- 309 Query: 583 NMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQ 642 + + K Q +E KLKE+ L K + Q Q+ Sbjct: 310 -------------IWKTKKQQKREEIFKLKEKADNTPVLFHNKQED-----NQKQKEEQR 351 Query: 643 ASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEK 678 KL A+KK S E S + ++E++KE+K Sbjct: 352 KKQKLAVEAWKKQKS-IEMSMKCASQLKEEEEKEKK 386 >gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo sapiens] Length = 446 Score = 38.9 bits (89), Expect = 0.016 Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 21/156 (13%) Query: 523 DIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAV 582 D D V V K KG + V++ G ++D+++ K +K+ + RKKE ++ Sbjct: 169 DYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQ-- 226 Query: 583 NMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQ 642 + + K Q +E KLKE+ L K + Q Q+ Sbjct: 227 -------------IWKTKKQQKREEIFKLKEKADNTPVLFHNKQED-----NQKQKEEQR 268 Query: 643 ASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEK 678 KL A+KK S E S + ++E++KE+K Sbjct: 269 KKQKLAVEAWKKQKS-IEMSMKCASQLKEEEEKEKK 303 >gi|34577114 cytomatrix protein p110 [Homo sapiens] Length = 957 Score = 37.7 bits (86), Expect = 0.035 Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 13/118 (11%) Query: 549 SSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPA--- 605 +S GL +D + +K+ E E+ + + ++EA I D EF DQ+ Sbjct: 654 ASAGLKRD---SKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDK 710 Query: 606 ------DECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMAS 657 DEC K + E+ ++ E+L ++E + ++ A L+ +L+ + KK+A+ Sbjct: 711 EASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIA-ELESLTLRHMKDQNKKVAN 767 >gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sapiens] Length = 1116 Score = 37.0 bits (84), Expect = 0.060 Identities = 26/99 (26%), Positives = 51/99 (51%), Gaps = 10/99 (10%) Query: 532 VSAKDKGTG--REQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGII 589 +S+ ++G E+ +++S+G LS ++ E +K E Y + K +VE + + Sbjct: 391 ISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEE---L 447 Query: 590 HDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSE 628 E + EE K + L+ EI ++++ L+RKD+E Sbjct: 448 SSKEAQWEELKKKAAG-----LQAEIGQVKQELSRKDTE 481 >gi|118498362 kinectin 1 isoform b [Homo sapiens] Length = 1306 Score = 36.6 bits (83), Expect = 0.078 Identities = 30/124 (24%), Positives = 63/124 (50%), Gaps = 13/124 (10%) Query: 533 SAKDKGTGREQQIV-IQSSGGLSKDDIENM--VKNAEKYAEEDRRKKERVEAVN------ 583 S +D+ T +E+++ IQ+ L K +++ + + N + A + K ++ V Sbjct: 625 SERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRL 684 Query: 584 MAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQA 643 + E + H+ KMEEFK + D+ LK E+ K++ L++ + ++ + + Q +Q+ Sbjct: 685 LEEQLQHEISNKMEEFK--ILNDQNKALKSEVQKLQTLVSEQPNK--DVVEQMEKCIQEK 740 Query: 644 SLKL 647 KL Sbjct: 741 DEKL 744 >gi|118498356 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 36.6 bits (83), Expect = 0.078 Identities = 30/124 (24%), Positives = 63/124 (50%), Gaps = 13/124 (10%) Query: 533 SAKDKGTGREQQIV-IQSSGGLSKDDIENM--VKNAEKYAEEDRRKKERVEAVN------ 583 S +D+ T +E+++ IQ+ L K +++ + + N + A + K ++ V Sbjct: 625 SERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRL 684 Query: 584 MAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQA 643 + E + H+ KMEEFK + D+ LK E+ K++ L++ + ++ + + Q +Q+ Sbjct: 685 LEEQLQHEISNKMEEFK--ILNDQNKALKSEVQKLQTLVSEQPNK--DVVEQMEKCIQEK 740 Query: 644 SLKL 647 KL Sbjct: 741 DEKL 744 >gi|118498368 kinectin 1 isoform c [Homo sapiens] Length = 1300 Score = 36.6 bits (83), Expect = 0.078 Identities = 30/124 (24%), Positives = 63/124 (50%), Gaps = 13/124 (10%) Query: 533 SAKDKGTGREQQIV-IQSSGGLSKDDIENM--VKNAEKYAEEDRRKKERVEAVN------ 583 S +D+ T +E+++ IQ+ L K +++ + + N + A + K ++ V Sbjct: 625 SERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRL 684 Query: 584 MAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQA 643 + E + H+ KMEEFK + D+ LK E+ K++ L++ + ++ + + Q +Q+ Sbjct: 685 LEEQLQHEISNKMEEFK--ILNDQNKALKSEVQKLQTLVSEQPNK--DVVEQMEKCIQEK 740 Query: 644 SLKL 647 KL Sbjct: 741 DEKL 744 >gi|33620775 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 36.6 bits (83), Expect = 0.078 Identities = 30/124 (24%), Positives = 63/124 (50%), Gaps = 13/124 (10%) Query: 533 SAKDKGTGREQQIV-IQSSGGLSKDDIENM--VKNAEKYAEEDRRKKERVEAVN------ 583 S +D+ T +E+++ IQ+ L K +++ + + N + A + K ++ V Sbjct: 625 SERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRL 684 Query: 584 MAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQA 643 + E + H+ KMEEFK + D+ LK E+ K++ L++ + ++ + + Q +Q+ Sbjct: 685 LEEQLQHEISNKMEEFK--ILNDQNKALKSEVQKLQTLVSEQPNK--DVVEQMEKCIQEK 740 Query: 644 SLKL 647 KL Sbjct: 741 DEKL 744 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 36.6 bits (83), Expect = 0.078 Identities = 37/142 (26%), Positives = 62/142 (43%), Gaps = 10/142 (7%) Query: 541 REQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFK 600 REQ+ + +D + M E+ E+D R +E+ E + + + E EE K Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKK 541 Query: 601 DQLPA----DECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMA 656 Q D+ K++EE +MRE +K E E +R+ +Q+ K+ E K Sbjct: 542 TQEQEKKTWDQEEKMREE-ERMRE-REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599 Query: 657 SEREGSGSSGTGEQKEDQKEEK 678 E + E+K ++EEK Sbjct: 600 QEEKMQEQ----EEKMWEQEEK 617 Score = 33.5 bits (75), Expect = 0.66 Identities = 32/138 (23%), Positives = 59/138 (42%), Gaps = 19/138 (13%) Query: 559 ENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKM 618 E + E+ E+ R +ER + + E ++ + E KM+E ++++ E K+ E+ KM Sbjct: 546 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKM 604 Query: 619 RELLAR---------------KDSETGENIRQAASSLQQASLKLFEMAYKKMASE---RE 660 +E + K E E + + +Q+ K++E K E RE Sbjct: 605 QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 664 Query: 661 GSGSSGTGEQKEDQKEEK 678 E+K ++EEK Sbjct: 665 QEEKMQGQEEKMREQEEK 682 >gi|32171186 B-cell receptor-associated protein 31 isoform b [Homo sapiens] Length = 246 Score = 36.6 bits (83), Expect = 0.078 Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 2/86 (2%) Query: 543 QQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQ 602 QQ + +S K E+ + A+KY EE+ + K+ AV+ + + + E K+EE Sbjct: 125 QQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGA-AVDGGKLDVGNAEVKLEEENRS 183 Query: 603 LPADECNKLKEEISKMRELLARKDSE 628 L AD KLK+E++ ++ L + +++ Sbjct: 184 LKAD-LQKLKDELASTKQKLEKAENQ 208 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.130 0.355 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,863,775 Number of Sequences: 37866 Number of extensions: 973630 Number of successful extensions: 3332 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 29 Number of HSP's successfully gapped in prelim test: 149 Number of HSP's that attempted gapping in prelim test: 3046 Number of HSP's gapped (non-prelim): 350 length of query: 679 length of database: 18,247,518 effective HSP length: 109 effective length of query: 570 effective length of database: 14,120,124 effective search space: 8048470680 effective search space used: 8048470680 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.