Search of human proteins with 24234686

Search of human proteins with 24234686

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
         (493 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]       972   0.0  
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]        912   0.0  
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]                 838   0.0  
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]               831   0.0  
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]               831   0.0  
gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]           815   0.0  
gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]       787   0.0  
gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]                 632   0.0  
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]       479   e-135
gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]      296   2e-80
gi|48928056 heat shock protein 70kDa family member 13 precursor ...   276   2e-74
gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]                 270   3e-72
gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]            261   1e-69
gi|42544159 heat shock 105kD [Homo sapiens]                           259   4e-69
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]          222   7e-58
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]            222   7e-58
gi|123317881 germ cell associated 1 isoform 4 [Homo sapiens]           35   0.16 
gi|123317861 germ cell associated 1 isoform 2 [Homo sapiens]           35   0.16 
gi|194363768 homeobox D9 [Homo sapiens]                                33   0.45 
gi|19923193 heat shock 70kD protein binding protein [Homo sapiens]     33   0.45 
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]              32   1.0  
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]             32   1.0  
gi|13994190 frizzled 8 [Homo sapiens]                                  32   1.0  
gi|33620755 YEATS domain containing 2 [Homo sapiens]                   32   1.0  
gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]                 32   1.3  
gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]                 32   1.3  
gi|209915591 ribosomal protein S6 kinase, 52kDa, polypeptide 1 i...    32   1.3  
gi|19923723 ribosomal protein S6 kinase, 52kDa, polypeptide 1 is...    32   1.3  
gi|157388900 inositol monophosphatase domain containing 1 [Homo ...    31   2.3  
gi|5031703 Ras-GTPase-activating protein SH3-domain-binding prot...    31   2.3  

>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
          Length = 493

 Score =  972 bits (2512), Expect = 0.0
 Identities = 493/493 (100%), Positives = 493/493 (100%)

Query: 1   MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
           MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
Sbjct: 1   MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60

Query: 61  MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 120
           MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS
Sbjct: 61  MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 120

Query: 121 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 180
           SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA
Sbjct: 121 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 180

Query: 181 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
           IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH
Sbjct: 181 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240

Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 300
           FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA
Sbjct: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 300

Query: 301 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 360
           RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN
Sbjct: 301 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 360

Query: 361 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 420
           KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI
Sbjct: 361 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 420

Query: 421 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFPGGGAPPS 480
           PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFPGGGAPPS
Sbjct: 421 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFPGGGAPPS 480

Query: 481 GGASSGPTIEEVD 493
           GGASSGPTIEEVD
Sbjct: 481 GGASSGPTIEEVD 493


>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
          Length = 646

 Score =  912 bits (2356), Expect = 0.0
 Identities = 467/473 (98%), Positives = 468/473 (98%), Gaps = 1/473 (0%)

Query: 1   MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
           MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
Sbjct: 1   MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60

Query: 61  MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 120
           MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS
Sbjct: 61  MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 120

Query: 121 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 180
           SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA
Sbjct: 121 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 180

Query: 181 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
           IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH
Sbjct: 181 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240

Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 300
           FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA
Sbjct: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 300

Query: 301 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 360
           RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN
Sbjct: 301 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 360

Query: 361 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 420
           KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI
Sbjct: 361 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 420

Query: 421 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473
           PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTG+P   P G P
Sbjct: 421 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPA-PRGVP 472



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 31/31 (100%), Positives = 31/31 (100%)

Query: 463 GMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 493
           GMPGGMPGGFPGGGAPPSGGASSGPTIEEVD
Sbjct: 616 GMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 646


>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
          Length = 639

 Score =  838 bits (2166), Expect = 0.0
 Identities = 425/474 (89%), Positives = 447/474 (94%), Gaps = 3/474 (0%)

Query: 2   SKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 61
           ++GPA+GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM
Sbjct: 3   ARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 62

Query: 62  NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121
           NPTNT+FDAKRLIGR+F+DA VQSDMKHWPF VV++ G+PKVQVEYKGETK+F+PEE+SS
Sbjct: 63  NPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISS 122

Query: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181
           MVLTKMKEIAEAYLG  V +AV+TVPAYFNDSQRQATKDAGTI GLNVLRIINEPTAAAI
Sbjct: 123 MVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAI 182

Query: 182 AYGLDKK--VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVN 239
           AYGLDKK   G E+NVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMV+
Sbjct: 183 AYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVS 242

Query: 240 HFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITR 299
           H   EFKRKHKKDI  NKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEG+DFYTSITR
Sbjct: 243 HLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITR 302

Query: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359
           ARFEELNADLFRGTL+PVEKALRDAKLDK QI +IVLVGGSTRIPKIQKLLQDFFNGKEL
Sbjct: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362

Query: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTT 419
           NKSINPDEAVAYGAAVQAAIL GDKSENVQDLLLLDVTPLSLGIETAGGVMT LIKRNTT
Sbjct: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTT 422

Query: 420 IPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473
           IPTKQTQTFTTYSDNQ  VL+QVYEGERAMTKDNNLLGKF+LTG+P   P G P
Sbjct: 423 IPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPA-PRGVP 475



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 18/27 (66%), Positives = 18/27 (66%), Gaps = 3/27 (11%)

Query: 467 GMPGGFPGGGAPPSGGASSGPTIEEVD 493
           G PGG  GGG     GAS GPTIEEVD
Sbjct: 616 GGPGGGSGGGG---SGASGGPTIEEVD 639


>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
          Length = 641

 Score =  831 bits (2147), Expect = 0.0
 Identities = 416/473 (87%), Positives = 445/473 (94%), Gaps = 1/473 (0%)

Query: 1   MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
           M+K  A+GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
Sbjct: 1   MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60

Query: 61  MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 120
           +NP NTVFDAKRLIGR+F D VVQSDMKHWPF V+ND  +PKVQV YKGETK+FYPEE+S
Sbjct: 61  LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS 120

Query: 121 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 180
           SMVLTKMKEIAEAYLG  VTNAV+TVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAA
Sbjct: 121 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 180

Query: 181 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
           IAYGLD+    ERNVLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+VNH
Sbjct: 181 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH 240

Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 300
           F+ EFKRKHKKDIS+NKRAVRRLRTACERAKRTLSSSTQAS+EIDSL+EGIDFYTSITRA
Sbjct: 241 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA 300

Query: 301 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 360
           RFEEL +DLFR TL+PVEKALRDAKLDK+QIHD+VLVGGSTRIPK+QKLLQDFFNG++LN
Sbjct: 301 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN 360

Query: 361 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 420
           KSINPDEAVAYGAAVQAAIL GDKSENVQDLLLLDV PLSLG+ETAGGVMT LIKRN+TI
Sbjct: 361 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI 420

Query: 421 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473
           PTKQTQ FTTYSDNQPGVLIQVYEGERAMTKDNNLLG+FEL+G+P   P G P
Sbjct: 421 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPA-PRGVP 472



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 21/37 (56%), Positives = 24/37 (64%), Gaps = 4/37 (10%)

Query: 457 GKFELTGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 493
           G ++  G PG  PGGF  G   P GG+ SGPTIEEVD
Sbjct: 609 GLYQGAGGPG--PGGF--GAQGPKGGSGSGPTIEEVD 641


>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
          Length = 641

 Score =  831 bits (2147), Expect = 0.0
 Identities = 416/473 (87%), Positives = 445/473 (94%), Gaps = 1/473 (0%)

Query: 1   MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60
           M+K  A+GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
Sbjct: 1   MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA 60

Query: 61  MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS 120
           +NP NTVFDAKRLIGR+F D VVQSDMKHWPF V+ND  +PKVQV YKGETK+FYPEE+S
Sbjct: 61  LNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEIS 120

Query: 121 SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA 180
           SMVLTKMKEIAEAYLG  VTNAV+TVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAA
Sbjct: 121 SMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAA 180

Query: 181 IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
           IAYGLD+    ERNVLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+VNH
Sbjct: 181 IAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNH 240

Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA 300
           F+ EFKRKHKKDIS+NKRAVRRLRTACERAKRTLSSSTQAS+EIDSL+EGIDFYTSITRA
Sbjct: 241 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRA 300

Query: 301 RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN 360
           RFEEL +DLFR TL+PVEKALRDAKLDK+QIHD+VLVGGSTRIPK+QKLLQDFFNG++LN
Sbjct: 301 RFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLN 360

Query: 361 KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI 420
           KSINPDEAVAYGAAVQAAIL GDKSENVQDLLLLDV PLSLG+ETAGGVMT LIKRN+TI
Sbjct: 361 KSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTI 420

Query: 421 PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473
           PTKQTQ FTTYSDNQPGVLIQVYEGERAMTKDNNLLG+FEL+G+P   P G P
Sbjct: 421 PTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPA-PRGVP 472



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 21/37 (56%), Positives = 24/37 (64%), Gaps = 4/37 (10%)

Query: 457 GKFELTGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD 493
           G ++  G PG  PGGF  G   P GG+ SGPTIEEVD
Sbjct: 609 GLYQGAGGPG--PGGF--GAQGPKGGSGSGPTIEEVD 641


>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
          Length = 641

 Score =  815 bits (2104), Expect = 0.0
 Identities = 407/472 (86%), Positives = 443/472 (93%), Gaps = 1/472 (0%)

Query: 2   SKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 61
           +KG A+GIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM
Sbjct: 4   AKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAM 63

Query: 62  NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121
           NP NTVFDAKRLIGR+F+D VVQ+DMK WPF V+N+ G+PKV V YKGE K+FYPEE+SS
Sbjct: 64  NPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISS 123

Query: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181
           MVLTK+KE AEA+LG  VTNAV+TVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAAI
Sbjct: 124 MVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 183

Query: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
           AYGLDK    ER+VLIFDLGGGTFDVSILTI+DGIFEVK+TAGDTHLGGEDFDNR+V+HF
Sbjct: 184 AYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHF 243

Query: 242 IAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRAR 301
           + EFKRKHKKDIS+NKRAVRRLRTACERAKRTLSSSTQA++EIDSLYEGIDFYTSITRAR
Sbjct: 244 VEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRAR 303

Query: 302 FEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNK 361
           FEEL ADLFRGTL+PVEKALRDAK+DK++IHDIVLVGGSTRIPK+Q+LLQD+FNG++LNK
Sbjct: 304 FEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDLNK 363

Query: 362 SINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIP 421
           SINPDEAVAYGAAVQAAIL GDKSE VQDLLLLDV PLSLG+ETAGGVMT LIKRN+TIP
Sbjct: 364 SINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIP 423

Query: 422 TKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473
           TKQTQ FTTYSDNQPGVLIQVYEGERAMTKDNNLLG+F+LTG+P   P G P
Sbjct: 424 TKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPA-PRGVP 474


>gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
          Length = 643

 Score =  787 bits (2032), Expect = 0.0
 Identities = 389/468 (83%), Positives = 433/468 (92%), Gaps = 1/468 (0%)

Query: 6   AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
           AVGIDLGTTYSCVGVFQ G+VEI+ANDQGNRTTPSYVAFTDTERL+GDAAK+Q A+NP N
Sbjct: 8   AVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHN 67

Query: 66  TVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
           TVFDAKRLIGR+F D  VQSDMKHWPF VV++ G+PKV+V Y+GE K+FYPEE+SSMVL+
Sbjct: 68  TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLS 127

Query: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
           KMKE AEAYLG+ V +AV+TVPAYFNDSQRQATKDAG IAGLNVLRIINEPTAAAIAYGL
Sbjct: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187

Query: 186 DKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEF 245
           D++   ERNVLIFDLGGGTFDVS+L+I+ G+FEVK+TAGDTHLGGEDFDNR+VNHF+ EF
Sbjct: 188 DRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEF 247

Query: 246 KRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEEL 305
           +RKH KD+S NKRA+RRLRTACERAKRTLSSSTQA++EIDSL+EG+DFYTSITRARFEEL
Sbjct: 248 RRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEEL 307

Query: 306 NADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINP 365
            +DLFR TL+PVEKALRDAKLDK+QIHD+VLVGGSTRIPK+QKLLQDFFNGKELNKSINP
Sbjct: 308 CSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKELNKSINP 367

Query: 366 DEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQT 425
           DEAVAYGAAVQAA+L GDK E VQDLLLLDV PLSLG+ETAGGVMT LI+RN TIPTKQT
Sbjct: 368 DEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQT 427

Query: 426 QTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473
           QTFTTYSDNQPGV IQVYEGERAMTKDNNLLG+FEL+G+P   P G P
Sbjct: 428 QTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPA-PRGVP 474



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 14/27 (51%), Positives = 16/27 (59%)

Query: 467 GMPGGFPGGGAPPSGGASSGPTIEEVD 493
           G+PGG   G     G  S+GP IEEVD
Sbjct: 617 GVPGGSSCGTQARQGDPSTGPIIEEVD 643


>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
          Length = 654

 Score =  632 bits (1630), Expect = 0.0
 Identities = 326/472 (69%), Positives = 391/472 (82%), Gaps = 6/472 (1%)

Query: 4   GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMN 62
           G  VGIDLGTTYSCVGVF++G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  N
Sbjct: 28  GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSN 87

Query: 63  PTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKG-ETKSFYPEEVSS 121
           P NTVFDAKRLIGR ++D  VQ D+K  PF VV    +P +QV+  G +TK+F PEE+S+
Sbjct: 88  PENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISA 147

Query: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181
           MVLTKMKE AEAYLGK VT+AVVTVPAYFND+QRQATKDAGTIAGLNV+RIINEPTAAAI
Sbjct: 148 MVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAI 207

Query: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
           AYGLDK+ G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++ HF
Sbjct: 208 AYGLDKREG-EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHF 266

Query: 242 IAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRAR 301
           I  +K+K  KD+ ++ RAV++LR   E+AKR LSS  QA IEI+S YEG DF  ++TRA+
Sbjct: 267 IKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAK 326

Query: 302 FEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNK 361
           FEELN DLFR T+ PV+K L D+ L KS I +IVLVGGSTRIPKIQ+L+++FFNGKE ++
Sbjct: 327 FEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSR 386

Query: 362 SINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIP 421
            INPDEAVAYGAAVQA +LSGD  ++  DL+LLDV PL+LGIET GGVMT LI RNT +P
Sbjct: 387 GINPDEAVAYGAAVQAGVLSGD--QDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVP 444

Query: 422 TKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473
           TK++Q F+T SDNQP V I+VYEGER +TKDN+LLG F+LTG+P   P G P
Sbjct: 445 TKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPA-PRGVP 495


>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
          Length = 679

 Score =  479 bits (1234), Expect = e-135
 Identities = 261/476 (54%), Positives = 334/476 (70%), Gaps = 16/476 (3%)

Query: 3   KGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAM 61
           KG  VGIDLGTT SCV V +  + +++ N +G RTTPS VAFT D ERL+G  AK Q   
Sbjct: 52  KGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVT 111

Query: 62  NPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSS 121
           NP NT +  KRLIGRR+DD  VQ D+K+ PF +V  A      VE  G  K + P ++ +
Sbjct: 112 NPNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVR-ASNGDAWVEAHG--KLYSPSQIGA 168

Query: 122 MVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAI 181
            VL KMKE AE YLG T  NAV+TVPAYFNDSQRQATKDAG I+GLNVLR+INEPTAAA+
Sbjct: 169 FVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAAL 228

Query: 182 AYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHF 241
           AYGLDK    ++ + ++DLGGGTFD+SIL I+ G+FEVKST GDT LGGEDFD  ++ H 
Sbjct: 229 AYGLDK--SEDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHI 286

Query: 242 IAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGID----FYTSI 297
           + EFKR+   D++++  A++R+R A E+AK  LSSS Q  I +  L             +
Sbjct: 287 VKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHLNMKL 346

Query: 298 TRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGK 357
           TRA+FE +  DL R T+ P +KA++DA++ KS I +++LVGG TR+PK+Q+ +QD F G+
Sbjct: 347 TRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLF-GR 405

Query: 358 ELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRN 417
             +K++NPDEAVA GAA+Q  +L+GD    V D+LLLDVTPLSLGIET GGV T LI RN
Sbjct: 406 APSKAVNPDEAVAIGAAIQGGVLAGD----VTDVLLLDVTPLSLGIETLGGVFTKLINRN 461

Query: 418 TTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFP 473
           TTIPTK++Q F+T +D Q  V I+V +GER M  DN LLG+F L G+P   P G P
Sbjct: 462 TTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPA-PRGVP 516


>gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]
          Length = 509

 Score =  296 bits (759), Expect = 2e-80
 Identities = 162/447 (36%), Positives = 263/447 (58%), Gaps = 8/447 (1%)

Query: 6   AVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
           A+G+ LG T +CV V++ G+  ++AND G+R TP+ VA+++ E ++G AAK     N +N
Sbjct: 3   AIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNISN 62

Query: 66  TVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
           TV   K+++GR   D   Q  +     +V+   G+ + +++   ETK   PE+V+ ++ +
Sbjct: 63  TVMKVKQILGRSSSDPQAQKYIAESKCLVIEKNGKLRYEIDTGEETKFVNPEDVARLIFS 122

Query: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
           KMKE A + LG    + V+TVP  F + Q+ A  +A   AG NVLR+I+EP+AA +AYG+
Sbjct: 123 KMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLAYGI 182

Query: 186 --DKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIA 243
             D   G + N+L+F LGG +  +S++ +  GI+ V ST  D ++GG  F   +  +  +
Sbjct: 183 GQDSPTG-KSNILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETLAQYLAS 241

Query: 244 EFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFE 303
           EF+R  K D+  N RA+ +L  + E AK +LS+   A+  +DSLYEG DF  +++RARFE
Sbjct: 242 EFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFE 301

Query: 304 ELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSI 363
            L + LF   ++ +   L         I+ +VL GGS+RIPK+Q+L++D F   EL  SI
Sbjct: 302 LLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKDLFPAVELLNSI 361

Query: 364 NPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTP---LSLGIETAGGV-MTVLIKRNTT 419
            PDE +  GAA++A IL G ++  V+D L+++ +    L  G++ +G    TVL    T 
Sbjct: 362 PPDEVIPIGAAIEAGILIGKENLLVEDSLMIECSARDILVKGVDESGASRFTVLFPSGTP 421

Query: 420 IPTKQTQTFTTYSDNQPGVLIQVYEGE 446
           +P ++  T      +   V +++YE +
Sbjct: 422 LPARRQHTLQA-PGSISSVCLELYESD 447


>gi|48928056 heat shock protein 70kDa family member 13 precursor
           [Homo sapiens]
          Length = 471

 Score =  276 bits (707), Expect = 2e-74
 Identities = 167/421 (39%), Positives = 246/421 (58%), Gaps = 50/421 (11%)

Query: 7   VGIDLGTTYSCVGVF--QHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPT 64
           +GIDLGTTY  VGVF    GKV++I ++ G+ + PS V+FTD +  +G  +      NP 
Sbjct: 34  IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQ 93

Query: 65  NTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVL 124
           NT++DAKR IG+ F    +++++  +PF V+N  G  +  V    ET +  PE V S +L
Sbjct: 94  NTIYDAKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLL 152

Query: 125 TKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYG 184
            K+KE+AEAYLG  V NAV++VPA F+  QR +T +A  +AGL +LR+INEPTAAA+AYG
Sbjct: 153 LKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYG 212

Query: 185 LDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAE 244
           L K      +VL+ DLGGGT DVS+L  + G+F  ++ +G+  LGG+DF+ R++ +   +
Sbjct: 213 LHK--ADVFHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQ 270

Query: 245 FKRKHKKDISENKRAVRRLRTACERAK--RTLSSSTQASIEI------------------ 284
             + +   +   K  + RLR A E  K   TL  S Q S+ +                  
Sbjct: 271 IYQTY-GFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELP 329

Query: 285 -DSLYEGID----------------------FYTSITRARFEELNADLFRGTLDPVEKAL 321
            D L    D                      F T I+R  F+ LN DLF+  L P+++ L
Sbjct: 330 KDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVL 389

Query: 322 RDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILS 381
           ++  L+K++I ++VLVGGSTRIP+I++++Q+FF GK+ N S++PD AV  G A+QA I  
Sbjct: 390 KEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGIDG 448

Query: 382 G 382
           G
Sbjct: 449 G 449


>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
          Length = 840

 Score =  270 bits (689), Expect = 3e-72
 Identities = 161/434 (37%), Positives = 244/434 (56%), Gaps = 15/434 (3%)

Query: 7   VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 66
           VGIDLG     V V + G +E IAN+  +R TP+ ++F    R IG AAK+QV  N  NT
Sbjct: 4   VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63

Query: 67  VFDAKRLIGRRFDDAVVQSDMKHWPFMVVN-DAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
           V   KR  GR F D  V+++  +  + +V    G   ++V Y  E ++F  E+V++M+L+
Sbjct: 64  VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123

Query: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
           K+KE AE+ L K V + VV+VP ++ D++R++  DA  IAGLN LR++NE TA A+AYG+
Sbjct: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183

Query: 186 DKK-----VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
            K+         RNV+  D+G   + VS+     G  +V +TA DT LGG  FD  +VNH
Sbjct: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243

Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGIDFYTSITR 299
           F  EF +K+K DI    RA+ RL   CE+ K+ +S +++   + I+     +D   ++ R
Sbjct: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303

Query: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359
            +F E+  DL      P+   L   KL K  I+ + +VGG+TRIP +++ +  FF GKEL
Sbjct: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362

Query: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIE-----TAGGVMTVLI 414
           + ++N DEAV  G A+Q AILS   +  V++  + DV P  + +        G     + 
Sbjct: 363 STTLNADEAVTRGCALQCAILS--PAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420

Query: 415 KRNTTIPTKQTQTF 428
            +N   P  +  TF
Sbjct: 421 SKNHAAPFSKVLTF 434


>gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]
          Length = 839

 Score =  261 bits (666), Expect = 1e-69
 Identities = 154/435 (35%), Positives = 246/435 (56%), Gaps = 17/435 (3%)

Query: 7   VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 66
           VGIDLG     + V + G +E IAN+  +R TP+ ++     R IG+AAK+Q+  N  NT
Sbjct: 4   VGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNT 63

Query: 67  VFDAKRLIGRRFDDAVVQSDMKHWPFMVVN-DAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
           +   K+L GR FDD +VQ++    P+ +     G   V+V Y  E + F  E+V+ M+L 
Sbjct: 64  IHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGMLLA 123

Query: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
           K+KE +E  L K V + V+++P++F D++R++   A  +AGLN LR++NE TA A+AYG+
Sbjct: 124 KLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGI 183

Query: 186 DKK-----VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
            K+         RNV+  D+G   + V +     G  +V +T  D +LGG +FD  +V++
Sbjct: 184 YKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEALVDY 243

Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGIDFYTSITR 299
           F  EFK K+K ++ EN RA+ RL   CE+ K+ +S +++   + I+     +D  + + R
Sbjct: 244 FCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNR 303

Query: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359
           A+FE+L A L      P++  +  A L +  I  I +VGG+TRIP +++ +  FF  K++
Sbjct: 304 AQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFL-KDI 362

Query: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSL------GIETAGGVMTVL 413
           + ++N DEAVA G A+Q AILS   +  V++  + D+ P S+        E   G   V 
Sbjct: 363 STTLNADEAVARGCALQCAILS--PAFKVREFSITDLVPYSITLRWKTSFEDGSGECEVF 420

Query: 414 IKRNTTIPTKQTQTF 428
            K N   P  +  TF
Sbjct: 421 CK-NHPAPFSKVITF 434


>gi|42544159 heat shock 105kD [Homo sapiens]
          Length = 858

 Score =  259 bits (662), Expect = 4e-69
 Identities = 159/435 (36%), Positives = 246/435 (56%), Gaps = 17/435 (3%)

Query: 7   VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 66
           VG+D+G+    + V + G +E IAN+  +R TPS ++F    R IG AAKNQ   +  NT
Sbjct: 4   VGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNT 63

Query: 67  VFDAKRLIGRRFDDAVVQSDMKHWPF-MVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
           V + KR  GR F+D  +Q + ++  + +V    G   ++V Y GE   F  E++++M+LT
Sbjct: 64  VSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLT 123

Query: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
           K+KE AE  L K VT+ V++VP++F D++R++  DA  I GLN LR++N+ TA A+ YG+
Sbjct: 124 KLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGI 183

Query: 186 DKK----VGAERNVLIF-DLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
            K+    +  +  +++F D+G   F VS      G  +V  TA D  LGG++FD ++V H
Sbjct: 184 YKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEH 243

Query: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSS-STQASIEIDSLYEGIDFYTSITR 299
           F AEFK K+K D     RA+ RL   CE+ K+ +SS ST   + I+      D    + R
Sbjct: 244 FCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNR 303

Query: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359
           ++FEEL A+L +    P+   L    L    +  + +VGG+TRIP +++ +  FF GK++
Sbjct: 304 SQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF-GKDI 362

Query: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGI------ETAGGVMTVL 413
           + ++N DEAVA G A+Q AILS   +  V++  + D  P  + +      E   GV  V 
Sbjct: 363 STTLNADEAVARGCALQCAILS--PAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEV- 419

Query: 414 IKRNTTIPTKQTQTF 428
             RN   P  +  TF
Sbjct: 420 FSRNHAAPFSKVLTF 434


>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
          Length = 999

 Score =  222 bits (565), Expect = 7e-58
 Identities = 146/456 (32%), Positives = 239/456 (52%), Gaps = 33/456 (7%)

Query: 7   VGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
           + +DLG+    V + + G  +EI+ N +  R TP  V   + ER  GD+A +    NP  
Sbjct: 36  MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95

Query: 66  TVFDAKRLIGRRFDDAVVQSDMKHWP-FMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVL 124
           T+   + L+G++ D+  V      +P   +  D  R  V  +   + + F PEEV  MVL
Sbjct: 96  TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQ-FSPEEVLGMVL 154

Query: 125 TKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYG 184
              + +AE +  + + +AV+TVP +FN ++R+A   A  +AGL VL++IN+ TA A++YG
Sbjct: 155 NYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYG 214

Query: 185 LDKKVGAE---RNVLIFDLGGGTFDVSILTI------EDGI---FEVKSTAGDTHLGGED 232
           + ++       +N++ +D+G G+   +I+T       E G+    +++    D  LGG +
Sbjct: 215 VFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLE 274

Query: 233 FDNRMVNHFIAEFKRKHK----KDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLY 288
            + R+       F  + K    KD+ EN RA+ +L     R K  LS++     +I+ L 
Sbjct: 275 MELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLM 334

Query: 289 EGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQK 348
           + +DF   +TR  FEEL ADLF     PV++AL+ A++   +I  ++LVGG+TR+P++Q+
Sbjct: 335 DDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQE 394

Query: 349 LLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLD--VTPLSL----- 401
           +L      +EL K+IN DEA A GA  QAA LS  K+  V+  ++ D  V P+ +     
Sbjct: 395 VLLKAVGKEELGKNINADEAAAMGAVYQAAALS--KAFKVKPFVVRDAVVYPILVEFTRE 452

Query: 402 -----GIETAGGVMTVLIKRNTTIPTKQTQTFTTYS 432
                GI +      VL  R    P ++  TF  YS
Sbjct: 453 VEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYS 488


>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
          Length = 999

 Score =  222 bits (565), Expect = 7e-58
 Identities = 146/456 (32%), Positives = 239/456 (52%), Gaps = 33/456 (7%)

Query: 7   VGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
           + +DLG+    V + + G  +EI+ N +  R TP  V   + ER  GD+A +    NP  
Sbjct: 36  MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95

Query: 66  TVFDAKRLIGRRFDDAVVQSDMKHWP-FMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVL 124
           T+   + L+G++ D+  V      +P   +  D  R  V  +   + + F PEEV  MVL
Sbjct: 96  TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQ-FSPEEVLGMVL 154

Query: 125 TKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYG 184
              + +AE +  + + +AV+TVP +FN ++R+A   A  +AGL VL++IN+ TA A++YG
Sbjct: 155 NYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYG 214

Query: 185 LDKKVGAE---RNVLIFDLGGGTFDVSILTI------EDGI---FEVKSTAGDTHLGGED 232
           + ++       +N++ +D+G G+   +I+T       E G+    +++    D  LGG +
Sbjct: 215 VFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLE 274

Query: 233 FDNRMVNHFIAEFKRKHK----KDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLY 288
            + R+       F  + K    KD+ EN RA+ +L     R K  LS++     +I+ L 
Sbjct: 275 MELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLM 334

Query: 289 EGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQK 348
           + +DF   +TR  FEEL ADLF     PV++AL+ A++   +I  ++LVGG+TR+P++Q+
Sbjct: 335 DDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQE 394

Query: 349 LLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLD--VTPLSL----- 401
           +L      +EL K+IN DEA A GA  QAA LS  K+  V+  ++ D  V P+ +     
Sbjct: 395 VLLKAVGKEELGKNINADEAAAMGAVYQAAALS--KAFKVKPFVVRDAVVYPILVEFTRE 452

Query: 402 -----GIETAGGVMTVLIKRNTTIPTKQTQTFTTYS 432
                GI +      VL  R    P ++  TF  YS
Sbjct: 453 VEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYS 488


>gi|123317881 germ cell associated 1 isoform 4 [Homo sapiens]
          Length = 362

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 15/91 (16%)

Query: 242 IAEFKRKHKKDISENKRAV--------RRLRTACERAKRTLSSSTQASIEIDSLYEGIDF 293
           + EFK KH K   EN   +        RRL +A        S     +  I S+ EG+DF
Sbjct: 273 VLEFKCKHSKSFKENPNCLPHHHQCFPRRLSSAAPTVGPLTSYHQYHNQPIHSVSEGVDF 332

Query: 294 YTSITRARFEELNADLFRGTLDPVEKALRDA 324
           Y+ +    F+       RG    +++A+R +
Sbjct: 333 YSELRNKGFQ-------RGASQELKEAVRSS 356


>gi|123317861 germ cell associated 1 isoform 2 [Homo sapiens]
          Length = 326

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 15/91 (16%)

Query: 242 IAEFKRKHKKDISENKRAV--------RRLRTACERAKRTLSSSTQASIEIDSLYEGIDF 293
           + EFK KH K   EN   +        RRL +A        S     +  I S+ EG+DF
Sbjct: 237 VLEFKCKHSKSFKENPNCLPHHHQCFPRRLSSAAPTVGPLTSYHQYHNQPIHSVSEGVDF 296

Query: 294 YTSITRARFEELNADLFRGTLDPVEKALRDA 324
           Y+ +    F+       RG    +++A+R +
Sbjct: 297 YSELRNKGFQ-------RGASQELKEAVRSS 320


>gi|194363768 homeobox D9 [Homo sapiens]
          Length = 352

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 15/28 (53%), Positives = 16/28 (57%)

Query: 461 LTGMPGGMPGGFPGGGAPPSGGASSGPT 488
           L G PGG  GG  GGG  P  G S GP+
Sbjct: 123 LPGFPGGAGGGGGGGGGGPGRGPSPGPS 150


>gi|19923193 heat shock 70kD protein binding protein [Homo sapiens]
          Length = 369

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 15/24 (62%), Positives = 15/24 (62%), Gaps = 1/24 (4%)

Query: 463 GMPGGMPGGFPGGGAPPSGGASSG 486
           G PGGMPG FP GG P  GG   G
Sbjct: 284 GFPGGMPGNFP-GGMPGMGGGMPG 306



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 15/31 (48%), Positives = 18/31 (58%), Gaps = 3/31 (9%)

Query: 463 GMPGGMPGGFPG-GGAPPSGGASSGPTIEEV 492
           GMPG  PGG PG GG  P  G +  P + E+
Sbjct: 288 GMPGNFPGGMPGMGGGMP--GMAGMPGLNEI 316


>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
          Length = 284

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 9/123 (7%)

Query: 218 EVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKK-DISENK--RAVRRLRTACERAKRTL 274
           E K  A D+    E+   ++V     E +R  ++ +++E++  +    LRT  +  K  +
Sbjct: 150 EAKHIAEDSDRKYEEVARKLVI-LEGELERSEERAEVAESRARQLEEELRTMDQALKSLM 208

Query: 275 SSSTQASIEIDSLYEGIDFYT-----SITRARFEELNADLFRGTLDPVEKALRDAKLDKS 329
           +S  + S + D   E I         + TRA F E +      T+D +E+ L  AK +  
Sbjct: 209 ASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENV 268

Query: 330 QIH 332
           +IH
Sbjct: 269 EIH 271


>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
          Length = 231

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 9/123 (7%)

Query: 218 EVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKK-DISENK--RAVRRLRTACERAKRTL 274
           E K  A D+    E+   ++V     E +R  ++ +++E++  +    LRT  +  K  +
Sbjct: 97  EAKHIAEDSDRKYEEVARKLVI-LEGELERSEERAEVAESRARQLEEELRTMDQALKSLM 155

Query: 275 SSSTQASIEIDSLYEGIDFYT-----SITRARFEELNADLFRGTLDPVEKALRDAKLDKS 329
           +S  + S + D   E I         + TRA F E +      T+D +E+ L  AK +  
Sbjct: 156 ASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENV 215

Query: 330 QIH 332
           +IH
Sbjct: 216 EIH 218


>gi|13994190 frizzled 8 [Homo sapiens]
          Length = 694

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 14/23 (60%), Positives = 14/23 (60%)

Query: 463 GMPGGMPGGFPGGGAPPSGGASS 485
           G PGG  GG PGGG  P GG  S
Sbjct: 642 GGPGGGGGGGPGGGGGPGGGGGS 664


>gi|33620755 YEATS domain containing 2 [Homo sapiens]
          Length = 1422

 Score = 32.3 bits (72), Expect = 1.0
 Identities = 44/146 (30%), Positives = 60/146 (41%), Gaps = 22/146 (15%)

Query: 359 LNKSINPDEAVAYGAAVQAAILSGDK----SENVQDLLLLDVT---PLSLGIETAGGVMT 411
           ++K++ P + V  G A   AI+SG      ++ VQ L    VT   P   G +  G VM 
Sbjct: 683 VSKAVGPKQVVTQGVA--KAIVSGGGGTIVAQPVQTLTKAQVTAAGPQKSGSQ--GSVMA 738

Query: 412 VL------IKRNTTIPTKQTQTFTTYSDNQPGV--LIQVYEGE--RAMTKDNNLLGKFEL 461
            L      +     +P       TT S N  G   L+ + +G   RA    N   G    
Sbjct: 739 TLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAAS 798

Query: 462 TGM-PGGMPGGFPGGGAPPSGGASSG 486
            G   GG  GG  GGG+   GG S+G
Sbjct: 799 GGSGAGGGGGGGGGGGSGSGGGGSTG 824


>gi|160420317 filamin A, alpha isoform 2 [Homo sapiens]
          Length = 2647

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 24/82 (29%), Positives = 32/82 (39%)

Query: 162  GTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKS 221
            G  AG      I+   A     GL  +   E  +   D G GT  VS +  E G + +  
Sbjct: 1079 GGSAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINI 1138

Query: 222  TAGDTHLGGEDFDNRMVNHFIA 243
               DTH+ G  F   +V  F A
Sbjct: 1139 LFADTHIPGSPFKAHVVPCFDA 1160


>gi|116063573 filamin A, alpha isoform 1 [Homo sapiens]
          Length = 2639

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 24/82 (29%), Positives = 32/82 (39%)

Query: 162  GTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKS 221
            G  AG      I+   A     GL  +   E  +   D G GT  VS +  E G + +  
Sbjct: 1079 GGSAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINI 1138

Query: 222  TAGDTHLGGEDFDNRMVNHFIA 243
               DTH+ G  F   +V  F A
Sbjct: 1139 LFADTHIPGSPFKAHVVPCFDA 1160


>gi|209915591 ribosomal protein S6 kinase, 52kDa, polypeptide 1
           isoform b [Homo sapiens]
          Length = 1054

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 4/113 (3%)

Query: 52  GDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVN--DAGRPKVQVEYKG 109
           GD+A      + +   F A+  I R  DD+V     K   F  V+  D GRP + V   G
Sbjct: 626 GDSASRSFNTSESKVEFKAQDTISRGSDDSVPVISFKDAAFDDVSGTDEGRPDLLVNLPG 685

Query: 110 ETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAG 162
           E +S    E ++M  TK  +     +   +  A   +    +  Q QA ++ G
Sbjct: 686 ELES--TREAAAMGPTKFTQTNIGIIENKLLEAPDVLCLRLSTEQCQAHEEKG 736


>gi|19923723 ribosomal protein S6 kinase, 52kDa, polypeptide 1
           isoform a [Homo sapiens]
          Length = 1066

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 4/113 (3%)

Query: 52  GDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVN--DAGRPKVQVEYKG 109
           GD+A      + +   F A+  I R  DD+V     K   F  V+  D GRP + V   G
Sbjct: 638 GDSASRSFNTSESKVEFKAQDTISRGSDDSVPVISFKDAAFDDVSGTDEGRPDLLVNLPG 697

Query: 110 ETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAG 162
           E +S    E ++M  TK  +     +   +  A   +    +  Q QA ++ G
Sbjct: 698 ELES--TREAAAMGPTKFTQTNIGIIENKLLEAPDVLCLRLSTEQCQAHEEKG 748


>gi|157388900 inositol monophosphatase domain containing 1 [Homo
           sapiens]
          Length = 359

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 13/54 (24%)

Query: 437 GVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFPGGGAPPSGGASSGPTIE 490
           GVL  +Y G         L G+F L G+     GG PGGGA     A+ G T++
Sbjct: 22  GVLYHLYSGF--------LAGRFSLFGL-----GGEPGGGAAGPAAAADGGTVD 62


>gi|5031703 Ras-GTPase-activating protein SH3-domain-binding protein
           [Homo sapiens]
          Length = 466

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 27/131 (20%)

Query: 358 ELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRN 417
           E++KS   D   +YG  V+  I SG K  N   ++  D  P+   +     +    ++ N
Sbjct: 350 EVDKSELKDFFQSYGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLN 409

Query: 418 TTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGMPGGMPGGFPGG-G 476
             +  K+T+                 EG+R   +DN L G       PGG  GG  GG  
Sbjct: 410 --VEEKKTRA--------------AREGDR---RDNRLRG-------PGGPRGGLGGGMR 443

Query: 477 APPSGGASSGP 487
            PP GG    P
Sbjct: 444 GPPRGGMVQKP 454


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,436,425
Number of Sequences: 37866
Number of extensions: 773980
Number of successful extensions: 3944
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3757
Number of HSP's gapped (non-prelim): 164
length of query: 493
length of database: 18,247,518
effective HSP length: 106
effective length of query: 387
effective length of database: 14,233,722
effective search space: 5508450414
effective search space used: 5508450414
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.