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Search of human proteins with 242247025
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|242247025 cyclin N-terminal domain containing 2 isoform 2
[Homo sapiens]
(307 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 612 e-175
gi|14327896 cyclin B1 [Homo sapiens] 101 7e-22
gi|4757930 cyclin B2 [Homo sapiens] 95 7e-20
gi|161377472 cyclin A1 isoform c [Homo sapiens] 91 1e-18
gi|161377470 cyclin A1 isoform c [Homo sapiens] 91 1e-18
gi|161377468 cyclin A1 isoform b [Homo sapiens] 91 1e-18
gi|4502611 cyclin A1 isoform a [Homo sapiens] 91 1e-18
gi|153791755 cyclin domain containing [Homo sapiens] 87 1e-17
gi|4502613 cyclin A [Homo sapiens] 82 5e-16
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 81 1e-15
gi|118572588 cyclin F [Homo sapiens] 71 1e-12
gi|16950655 cyclin D1 [Homo sapiens] 68 9e-12
gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 62 5e-10
gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 62 5e-10
gi|5802992 cyclin I [Homo sapiens] 62 6e-10
gi|17318565 cyclin E2 [Homo sapiens] 61 1e-09
gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 60 2e-09
gi|4502617 cyclin D2 [Homo sapiens] 56 4e-08
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 54 2e-07
gi|40805832 cyclin G1 [Homo sapiens] 49 6e-06
gi|4757934 cyclin G1 [Homo sapiens] 49 6e-06
gi|4757936 cyclin G2 [Homo sapiens] 43 3e-04
gi|89886237 cyclin I family, member 2 [Homo sapiens] 40 0.003
gi|197276674 cyclin J isoform 1 [Homo sapiens] 39 0.008
gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 37 0.022
gi|197276676 cyclin J isoform 3 [Homo sapiens] 36 0.037
gi|40254889 cyclin J isoform 2 [Homo sapiens] 36 0.037
gi|150417989 cyclin K isoform 1 [Homo sapiens] 35 0.084
gi|38176158 cyclin K isoform 2 [Homo sapiens] 35 0.084
gi|9945320 cyclin L1 [Homo sapiens] 33 0.41
>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
sapiens]
Length = 307
Score = 612 bits (1577), Expect = e-175
Identities = 307/307 (100%), Positives = 307/307 (100%)
Query: 1 MLVRGRDQGSGSRLGPIVRRWAPRPSPLQSLAASLDAEPSSAAVPDGFPAGPTVSPRRLA 60
MLVRGRDQGSGSRLGPIVRRWAPRPSPLQSLAASLDAEPSSAAVPDGFPAGPTVSPRRLA
Sbjct: 1 MLVRGRDQGSGSRLGPIVRRWAPRPSPLQSLAASLDAEPSSAAVPDGFPAGPTVSPRRLA 60
Query: 61 RPPGLEEALSALGLQGEREYAGDIFAEVMVCRVLPLRALPRAVTPEMRALVVDWLVQVHE 120
RPPGLEEALSALGLQGEREYAGDIFAEVMVCRVLPLRALPRAVTPEMRALVVDWLVQVHE
Sbjct: 61 RPPGLEEALSALGLQGEREYAGDIFAEVMVCRVLPLRALPRAVTPEMRALVVDWLVQVHE 120
Query: 121 YLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLCLLSA 180
YLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLCLLSA
Sbjct: 121 YLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLCLLSA 180
Query: 181 DSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELSLLEA 240
DSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELSLLEA
Sbjct: 181 DSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELSLLEA 240
Query: 241 EAAGWEPGRRAAAALSLAHRLLDGAGSRLQPELYRCSLGGGSVWGHRSFRDLPSWSFLRS 300
EAAGWEPGRRAAAALSLAHRLLDGAGSRLQPELYRCSLGGGSVWGHRSFRDLPSWSFLRS
Sbjct: 241 EAAGWEPGRRAAAALSLAHRLLDGAGSRLQPELYRCSLGGGSVWGHRSFRDLPSWSFLRS 300
Query: 301 RRMRDNY 307
RRMRDNY
Sbjct: 301 RRMRDNY 307
>gi|14327896 cyclin B1 [Homo sapiens]
Length = 433
Score = 101 bits (252), Expect = 7e-22
Identities = 62/189 (32%), Positives = 101/189 (53%), Gaps = 4/189 (2%)
Query: 79 EYAGDIFAEVMVCR----VLPLRALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVH 134
EY DI+A + V P L R VT MRA+++DWLVQV L +T+Y+ V
Sbjct: 169 EYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVS 228
Query: 135 LLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERR 194
++D ++ V LQL+GV +F+A K EE PE ++ +++++ ++ + E +
Sbjct: 229 IIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMK 288
Query: 195 ILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELSLLEAEAAGWEPGRRAAAA 254
IL L+F L P PL L + + + LA Y +EL++L+ + + P + AA A
Sbjct: 289 ILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGA 348
Query: 255 LSLAHRLLD 263
LA ++LD
Sbjct: 349 FCLALKILD 357
>gi|4757930 cyclin B2 [Homo sapiens]
Length = 398
Score = 95.1 bits (235), Expect = 7e-20
Identities = 61/200 (30%), Positives = 99/200 (49%), Gaps = 4/200 (2%)
Query: 79 EYAGDIFAEVMVCRVL----PLRALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVH 134
+Y DI+ + VL P R + MRA++VDWLVQVH L +TLY+ V
Sbjct: 133 DYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCVG 192
Query: 135 LLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERR 194
++D +L V +LQL+G+ L +A K EE P ++ ++++ +++ E
Sbjct: 193 IMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETL 252
Query: 195 ILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELSLLEAEAAGWEPGRRAAAA 254
IL L F L P PL L + + LA Y +EL+L++ + + P + AAAA
Sbjct: 253 ILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYDMVHYHPSKVAAAA 312
Query: 255 LSLAHRLLDGAGSRLQPELY 274
L+ ++L L+ + Y
Sbjct: 313 SCLSQKVLGQGKWNLKQQYY 332
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 91.3 bits (225), Expect = 1e-18
Identities = 73/204 (35%), Positives = 104/204 (50%), Gaps = 14/204 (6%)
Query: 67 EALSALGLQ--GEREYAGDIFAEVMVCRVLPLRALPRA--------VTPEMRALVVDWLV 116
E +S+LG EYA +I+ + R +R P+A +T MR ++VDWLV
Sbjct: 152 EDISSLGTDVINVTEYAEEIYQYL---REAEIRHRPKAHYMKKQPDITEGMRTILVDWLV 208
Query: 117 QVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLC 176
+V E L +TLYLAV+ LD +LS V +LQL+G A + +A K EE PE
Sbjct: 209 EVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFV 268
Query: 177 LLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELS 236
++ D++++ +LL+ E +L L F L P L G + LA Y ELS
Sbjct: 269 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELS 328
Query: 237 LLEAEA-AGWEPGRRAAAALSLAH 259
LLEA+ + P AAAA LA+
Sbjct: 329 LLEADPFLKYLPSLIAAAAFCLAN 352
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 91.3 bits (225), Expect = 1e-18
Identities = 73/204 (35%), Positives = 104/204 (50%), Gaps = 14/204 (6%)
Query: 67 EALSALGLQ--GEREYAGDIFAEVMVCRVLPLRALPRA--------VTPEMRALVVDWLV 116
E +S+LG EYA +I+ + R +R P+A +T MR ++VDWLV
Sbjct: 152 EDISSLGTDVINVTEYAEEIYQYL---REAEIRHRPKAHYMKKQPDITEGMRTILVDWLV 208
Query: 117 QVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLC 176
+V E L +TLYLAV+ LD +LS V +LQL+G A + +A K EE PE
Sbjct: 209 EVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFV 268
Query: 177 LLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELS 236
++ D++++ +LL+ E +L L F L P L G + LA Y ELS
Sbjct: 269 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELS 328
Query: 237 LLEAEA-AGWEPGRRAAAALSLAH 259
LLEA+ + P AAAA LA+
Sbjct: 329 LLEADPFLKYLPSLIAAAAFCLAN 352
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 91.3 bits (225), Expect = 1e-18
Identities = 73/204 (35%), Positives = 104/204 (50%), Gaps = 14/204 (6%)
Query: 67 EALSALGLQ--GEREYAGDIFAEVMVCRVLPLRALPRA--------VTPEMRALVVDWLV 116
E +S+LG EYA +I+ + R +R P+A +T MR ++VDWLV
Sbjct: 195 EDISSLGTDVINVTEYAEEIYQYL---REAEIRHRPKAHYMKKQPDITEGMRTILVDWLV 251
Query: 117 QVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLC 176
+V E L +TLYLAV+ LD +LS V +LQL+G A + +A K EE PE
Sbjct: 252 EVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFV 311
Query: 177 LLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELS 236
++ D++++ +LL+ E +L L F L P L G + LA Y ELS
Sbjct: 312 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELS 371
Query: 237 LLEAEA-AGWEPGRRAAAALSLAH 259
LLEA+ + P AAAA LA+
Sbjct: 372 LLEADPFLKYLPSLIAAAAFCLAN 395
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 91.3 bits (225), Expect = 1e-18
Identities = 73/204 (35%), Positives = 104/204 (50%), Gaps = 14/204 (6%)
Query: 67 EALSALGLQ--GEREYAGDIFAEVMVCRVLPLRALPRA--------VTPEMRALVVDWLV 116
E +S+LG EYA +I+ + R +R P+A +T MR ++VDWLV
Sbjct: 196 EDISSLGTDVINVTEYAEEIYQYL---REAEIRHRPKAHYMKKQPDITEGMRTILVDWLV 252
Query: 117 QVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLC 176
+V E L +TLYLAV+ LD +LS V +LQL+G A + +A K EE PE
Sbjct: 253 EVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFV 312
Query: 177 LLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELS 236
++ D++++ +LL+ E +L L F L P L G + LA Y ELS
Sbjct: 313 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELS 372
Query: 237 LLEAEA-AGWEPGRRAAAALSLAH 259
LLEA+ + P AAAA LA+
Sbjct: 373 LLEADPFLKYLPSLIAAAAFCLAN 396
>gi|153791755 cyclin domain containing [Homo sapiens]
Length = 350
Score = 87.4 bits (215), Expect = 1e-17
Identities = 80/253 (31%), Positives = 107/253 (42%), Gaps = 18/253 (7%)
Query: 23 PRPSPLQSLAASLDAEPSSAAVPDGFPAGPTVSPRRLARP-PGLEEALSALGLQGEREYA 81
P P P S L PSS G + S R P PG + ++ L LQ R+Y
Sbjct: 48 PCPLPGDSGICDLFESPSS-----GSDGAESPSAARGGSPLPGPAQPVAQLDLQTFRDYG 102
Query: 82 GDIFA--EVMVCRVLPLRALPRA--VTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLD 137
+A + P AL R VT E R ++ WL+ VH GL+ ++L L V+ LD
Sbjct: 103 QSCYAFRKAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLD 162
Query: 138 SYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERRILS 197
+L+ V QLLGV L +ACK E P L L +FSR +L E +L
Sbjct: 163 RFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLH 222
Query: 198 RLDFRLHHPGPLLCLGLLA--------ALAGSSPQVMLLATYFLELSLLEAEAAGWEPGR 249
+L F L P L A A + + LA ELSL + + P
Sbjct: 223 KLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSL 282
Query: 250 RAAAALSLAHRLL 262
A L+LA R+L
Sbjct: 283 LAICCLALADRML 295
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 82.4 bits (202), Expect = 5e-16
Identities = 58/160 (36%), Positives = 88/160 (55%), Gaps = 6/160 (3%)
Query: 103 VTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVAC 162
+T MRA++VDWLV+V E L +TL+LAV+ +D +LS+ V +LQL+G A + +A
Sbjct: 206 ITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLAS 265
Query: 163 KMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSS 222
K EE PE A ++ D++++ ++LR E +L L F L P + L
Sbjct: 266 KFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDL--AAPTVNQFLTQYFLHQQ 323
Query: 223 P---QVMLLATYFLELSLLEAEA-AGWEPGRRAAAALSLA 258
P +V LA + ELSL++A+ + P A AA LA
Sbjct: 324 PANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLA 363
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 81.3 bits (199), Expect = 1e-15
Identities = 52/156 (33%), Positives = 81/156 (51%)
Query: 103 VTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVAC 162
+T +MRA++VDWLV+V + +TLYLAV L+D YL + +LQLLG +A
Sbjct: 1156 ITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAA 1215
Query: 163 KMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSS 222
K EE P + D++ R+E+L E IL+ L ++ P L A ++
Sbjct: 1216 KFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTN 1275
Query: 223 PQVMLLATYFLELSLLEAEAAGWEPGRRAAAALSLA 258
+ + L+ Y E++L E + + AAA+L LA
Sbjct: 1276 MKTLTLSRYICEMTLQEYHYVQEKASKLAAASLLLA 1311
>gi|118572588 cyclin F [Homo sapiens]
Length = 786
Score = 70.9 bits (172), Expect = 1e-12
Identities = 49/167 (29%), Positives = 82/167 (49%), Gaps = 1/167 (0%)
Query: 98 ALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVAC 157
++ + + MR +++DWLV+V L+L V +D YL V +RLQLLG+AC
Sbjct: 300 SVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIAC 359
Query: 158 LFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAA 217
+ + + + L+ +++ +L+R I+S L+ ++ P + +L
Sbjct: 360 MVICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLT 419
Query: 218 LAGSSPQVMLLATYFLELSLLEAEAAGWEPGRRAAAALSLAHRLLDG 264
L + L ++ ELSLL + + P R AAAAL LA RL G
Sbjct: 420 LVPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLA-RLTHG 465
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 68.2 bits (165), Expect = 9e-12
Identities = 37/107 (34%), Positives = 61/107 (57%)
Query: 97 RALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVA 156
+ + + V P MR +V W+++V E + LA++ LD +LS V+ RLQLLG
Sbjct: 46 KCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGAT 105
Query: 157 CLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRL 203
C+FVA KM+E + LC+ + +S ELL+ E ++++L + L
Sbjct: 106 CMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNL 152
>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
Length = 410
Score = 62.4 bits (150), Expect = 5e-10
Identities = 49/166 (29%), Positives = 79/166 (47%), Gaps = 18/166 (10%)
Query: 105 PEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSA-GRVRLHRLQLLGVACLFVACK 163
P+MRA+++DWL++V E L +T YLA D Y++ V LQL+G++ LF+A K
Sbjct: 142 PKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAK 201
Query: 164 MEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLL-------- 215
+EE P+ ++ + S E+L E I+ L +RL PL + L
Sbjct: 202 LEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRL---SPLTIVSWLNVYMQVAY 258
Query: 216 ------AALAGSSPQVMLLATYFLELSLLEAEAAGWEPGRRAAAAL 255
L Q+ + L+L +L+ + + G AA+AL
Sbjct: 259 LNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASAL 304
>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
Length = 395
Score = 62.4 bits (150), Expect = 5e-10
Identities = 49/166 (29%), Positives = 79/166 (47%), Gaps = 18/166 (10%)
Query: 105 PEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSA-GRVRLHRLQLLGVACLFVACK 163
P+MRA+++DWL++V E L +T YLA D Y++ V LQL+G++ LF+A K
Sbjct: 127 PKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAK 186
Query: 164 MEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLL-------- 215
+EE P+ ++ + S E+L E I+ L +RL PL + L
Sbjct: 187 LEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRL---SPLTIVSWLNVYMQVAY 243
Query: 216 ------AALAGSSPQVMLLATYFLELSLLEAEAAGWEPGRRAAAAL 255
L Q+ + L+L +L+ + + G AA+AL
Sbjct: 244 LNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASAL 289
>gi|5802992 cyclin I [Homo sapiens]
Length = 377
Score = 62.0 bits (149), Expect = 6e-10
Identities = 45/128 (35%), Positives = 69/128 (53%), Gaps = 5/128 (3%)
Query: 103 VTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVAC 162
V+P R V+ WL ++ L +T LA LLD +L+ + L + ++C F+A
Sbjct: 40 VSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAA 99
Query: 163 KMEECVLPEPAFLCLLSADSF---SRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALA 219
K E P L +L+ DSF S +E+LR ER IL +L++ LH PL L + A+A
Sbjct: 100 KTVEEDERIPV-LKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIA 158
Query: 220 GSS-PQVM 226
S+ PQ++
Sbjct: 159 VSTRPQLL 166
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 61.2 bits (147), Expect = 1e-09
Identities = 33/100 (33%), Positives = 57/100 (57%), Gaps = 1/100 (1%)
Query: 105 PEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGR-VRLHRLQLLGVACLFVACK 163
P+MR++++DWL++V E L +T YLA D ++ + + + LQL+G+ LF+A K
Sbjct: 139 PQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASK 198
Query: 164 MEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRL 203
+EE P+ ++ + S ++LR E IL L + L
Sbjct: 199 LEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWEL 238
>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
Length = 291
Score = 60.1 bits (144), Expect = 2e-09
Identities = 42/132 (31%), Positives = 65/132 (49%)
Query: 127 DTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLCLLSADSFSRA 186
+TLYLAV L+D YL + +LQLLG +A K EE P + D++ R+
Sbjct: 76 ETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRS 135
Query: 187 ELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELSLLEAEAAGWE 246
E+L E IL+ L ++ P L A ++ + + L+ Y E++L E +
Sbjct: 136 EVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYHYVQEK 195
Query: 247 PGRRAAAALSLA 258
+ AAA+L LA
Sbjct: 196 ASKLAAASLLLA 207
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 56.2 bits (134), Expect = 4e-08
Identities = 32/107 (29%), Positives = 55/107 (51%)
Query: 97 RALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVA 156
+ + + + P MR +V W+++V E + LA++ LD +L+ LQLLG
Sbjct: 45 KCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAV 104
Query: 157 CLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRL 203
C+F+A K++E LC+ + +S ELL E +L +L + L
Sbjct: 105 CMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNL 151
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 53.9 bits (128), Expect = 2e-07
Identities = 35/117 (29%), Positives = 57/117 (48%)
Query: 87 EVMVCRVLPLRALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVR 146
E V R + + R + P MR ++ W+++V E + LA++ LD YLS R
Sbjct: 36 ERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTR 95
Query: 147 LHRLQLLGVACLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRL 203
+LQLLG C+ +A K+ E LC+ + + S +L E +L +L + L
Sbjct: 96 KAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDL 152
>gi|40805832 cyclin G1 [Homo sapiens]
Length = 295
Score = 48.9 bits (115), Expect = 6e-06
Identities = 30/103 (29%), Positives = 59/103 (57%), Gaps = 2/103 (1%)
Query: 103 VTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVAC 162
+T +R V L+ + ++ G +T LAV+LLD +LS +V+ L +G++C ++A
Sbjct: 47 MTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAV 106
Query: 163 KM--EECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRL 203
K EE +P L +S F+ ++L+R E+ +L ++ +++
Sbjct: 107 KSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKV 149
>gi|4757934 cyclin G1 [Homo sapiens]
Length = 295
Score = 48.9 bits (115), Expect = 6e-06
Identities = 30/103 (29%), Positives = 59/103 (57%), Gaps = 2/103 (1%)
Query: 103 VTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVAC 162
+T +R V L+ + ++ G +T LAV+LLD +LS +V+ L +G++C ++A
Sbjct: 47 MTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAV 106
Query: 163 KM--EECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRL 203
K EE +P L +S F+ ++L+R E+ +L ++ +++
Sbjct: 107 KSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKV 149
>gi|4757936 cyclin G2 [Homo sapiens]
Length = 344
Score = 43.1 bits (100), Expect = 3e-04
Identities = 26/101 (25%), Positives = 52/101 (51%), Gaps = 2/101 (1%)
Query: 105 PEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKM 164
P +R V+ L + + G +T LAV++LD +L+ +V+ L +GV +A ++
Sbjct: 53 PGLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARI 112
Query: 165 --EECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRL 203
E+C +P + +S + +++ R E+ I +L + L
Sbjct: 113 VEEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYEL 153
>gi|89886237 cyclin I family, member 2 [Homo sapiens]
Length = 369
Score = 39.7 bits (91), Expect = 0.003
Identities = 55/220 (25%), Positives = 88/220 (40%), Gaps = 22/220 (10%)
Query: 23 PRPSPLQSLAASLDAEPSSAAVPDGFPAG--PTVSPRRLARPPGLEEALSALGLQGEREY 80
P + L + +A++ P P G A P +P + RP A + R
Sbjct: 62 PGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAPRP--------APQSRKPRNL 113
Query: 81 AGDIFAEVMVCRVLPLR----ALPRAVTPEMRAL-----VVDWLVQVHEYLGLAGDTLYL 131
GD+ ++C + + L R P+ VV WL+++ + T L
Sbjct: 114 EGDLDERRLLCHLQLAQDREARLWRGGKPQDEICDAFEEVVLWLLRLQNTFYFSQSTFNL 173
Query: 132 AVHLLDSYLSAGRVRLHRLQLLGVACLFVACKM--EECVLPEPAFLCLLSADSFSRAELL 189
A+ + L + +V+ L + L +A K+ EE +P+ +S ELL
Sbjct: 174 ALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELL 233
Query: 190 RAERRILSRLDFRLHHPGPLLCLGLLAALAGSS-PQVMLL 228
R E IL RL + L+ PL L + AL S P V+ L
Sbjct: 234 RMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLEL 273
>gi|197276674 cyclin J isoform 1 [Homo sapiens]
Length = 383
Score = 38.5 bits (88), Expect = 0.008
Identities = 41/185 (22%), Positives = 73/185 (39%), Gaps = 35/185 (18%)
Query: 107 MRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEE 166
+R D + V L +LAV+LLD ++ + + +L L+ ++CL +A K EE
Sbjct: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEE 98
Query: 167 CVLPEP------AFLCLLSAD-SFSRAELLRAERRILSRLDFR----------------- 202
P + C+ + + ++ LL E +L +
Sbjct: 99 KEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEA 158
Query: 203 -----LHHPGPLLCLGLLAALAGSSPQVMLLATYFLELSLLEAEAAGWEPGRRAAAALSL 257
LH P++C L + + A YFLE+SL + + P AAA ++
Sbjct: 159 VHETDLHDGWPMIC------LEKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVAS 212
Query: 258 AHRLL 262
+ +L
Sbjct: 213 SRIIL 217
>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
Length = 211
Score = 37.0 bits (84), Expect = 0.022
Identities = 23/71 (32%), Positives = 36/71 (50%)
Query: 133 VHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAE 192
++ LD YLS R +LQLLG C+ +A K+ E LC+ + + S +L E
Sbjct: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
Query: 193 RRILSRLDFRL 203
+L +L + L
Sbjct: 61 VLVLGKLKWDL 71
>gi|197276676 cyclin J isoform 3 [Homo sapiens]
Length = 371
Score = 36.2 bits (82), Expect = 0.037
Identities = 23/90 (25%), Positives = 41/90 (45%)
Query: 107 MRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEE 166
+R D + V L +LAV+LLD ++ + + +L L+ ++CL +A K EE
Sbjct: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEE 98
Query: 167 CVLPEPAFLCLLSADSFSRAELLRAERRIL 196
P L S + L+ ++ +L
Sbjct: 99 KEDSVPKLEQLNSLGCMTNMNLVLTKQNLL 128
>gi|40254889 cyclin J isoform 2 [Homo sapiens]
Length = 372
Score = 36.2 bits (82), Expect = 0.037
Identities = 23/90 (25%), Positives = 41/90 (45%)
Query: 107 MRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEE 166
+R D + V L +LAV+LLD ++ + + +L L+ ++CL +A K EE
Sbjct: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEE 98
Query: 167 CVLPEPAFLCLLSADSFSRAELLRAERRIL 196
P L S + L+ ++ +L
Sbjct: 99 KEDSVPKLEQLNSLGCMTNMNLVLTKQNLL 128
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 35.0 bits (79), Expect = 0.084
Identities = 48/181 (26%), Positives = 69/181 (38%), Gaps = 16/181 (8%)
Query: 96 LRALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGV 155
L L A R ++ V LGL DTL + + + + G
Sbjct: 38 LEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGA 97
Query: 156 ACLFVACKMEE----CVLPEPAFLCLLSADSFS------RAELLRAERRILS--RLDFRL 203
CLF+A K+EE C LL+ F + E++ ER +L + D ++
Sbjct: 98 CCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQV 157
Query: 204 HHPGPLLCLGLLAALAGSSPQVMLL---ATYFLELSLLEAEAAGWEPGRRAAAALSLAHR 260
HP L L L G ++ L A F+ SL + WEP A A + LA R
Sbjct: 158 EHPYQFL-LKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGR 216
Query: 261 L 261
L
Sbjct: 217 L 217
>gi|38176158 cyclin K isoform 2 [Homo sapiens]
Length = 354
Score = 35.0 bits (79), Expect = 0.084
Identities = 48/181 (26%), Positives = 69/181 (38%), Gaps = 16/181 (8%)
Query: 96 LRALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGV 155
L L A R ++ V LGL DTL + + + + G
Sbjct: 38 LEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGA 97
Query: 156 ACLFVACKMEE----CVLPEPAFLCLLSADSFS------RAELLRAERRILS--RLDFRL 203
CLF+A K+EE C LL+ F + E++ ER +L + D ++
Sbjct: 98 CCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQV 157
Query: 204 HHPGPLLCLGLLAALAGSSPQVMLL---ATYFLELSLLEAEAAGWEPGRRAAAALSLAHR 260
HP L L L G ++ L A F+ SL + WEP A A + LA R
Sbjct: 158 EHPYQFL-LKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGR 216
Query: 261 L 261
L
Sbjct: 217 L 217
>gi|9945320 cyclin L1 [Homo sapiens]
Length = 526
Score = 32.7 bits (73), Expect = 0.41
Identities = 31/135 (22%), Positives = 58/135 (42%), Gaps = 20/135 (14%)
Query: 148 HRLQLLGVACLFVACKMEECVLP------------------EPAFLCLLSADSFSRAELL 189
H +++ +AC+ +A K+EE P+ L L ++ +++
Sbjct: 123 HSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVI 182
Query: 190 RAERRILSRLDFRLH--HPGPLLCLGLLAALAGSSPQVMLLATYFLELSLLEAEAAGWEP 247
+AERR+L L F +H HP ++ + L + ++ A ++ SL ++P
Sbjct: 183 KAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQP 242
Query: 248 GRRAAAALSLAHRLL 262
A A + LA R L
Sbjct: 243 ETIACACIYLAARAL 257
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.139 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,269,889
Number of Sequences: 37866
Number of extensions: 657849
Number of successful extensions: 3210
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 3138
Number of HSP's gapped (non-prelim): 109
length of query: 307
length of database: 18,247,518
effective HSP length: 102
effective length of query: 205
effective length of database: 14,385,186
effective search space: 2948963130
effective search space used: 2948963130
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.