BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239756943 PREDICTED: hypothetical protein [Homo sapiens] (783 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239756943 PREDICTED: hypothetical protein [Homo sapiens] 1647 0.0 gi|239751443 PREDICTED: hypothetical protein [Homo sapiens] 1647 0.0 gi|239745948 PREDICTED: hypothetical protein XP_002343622 [Homo ... 1640 0.0 gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo sap... 45 3e-04 gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo sap... 45 3e-04 gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo sapi... 45 3e-04 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 45 3e-04 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 42 0.002 gi|27894378 chloride intracellular channel 6 [Homo sapiens] 41 0.004 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 41 0.005 gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 40 0.008 gi|156616290 collagen type VI alpha 6 [Homo sapiens] 40 0.011 gi|91208420 bassoon protein [Homo sapiens] 40 0.011 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 40 0.011 gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 40 0.011 gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens] 39 0.014 gi|160707881 formin 2 [Homo sapiens] 39 0.019 gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like ... 39 0.024 gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 39 0.024 gi|169214011 PREDICTED: hypothetical protein [Homo sapiens] 38 0.032 gi|239756028 PREDICTED: hypothetical protein [Homo sapiens] 38 0.032 gi|113428768 PREDICTED: hypothetical protein [Homo sapiens] 38 0.032 gi|113428351 PREDICTED: hypothetical protein [Homo sapiens] 38 0.032 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 37 0.054 gi|122937233 discs, large (Drosophila) homolog-associated protei... 37 0.071 gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 37 0.071 gi|4502081 amphiphysin isoform 1 [Homo sapiens] 37 0.092 gi|154146231 DMRT-like family A2 [Homo sapiens] 37 0.092 gi|60097902 filaggrin [Homo sapiens] 36 0.12 gi|239751449 PREDICTED: hypothetical protein XP_002347867 [Homo ... 36 0.12 >gi|239756943 PREDICTED: hypothetical protein [Homo sapiens] Length = 783 Score = 1647 bits (4266), Expect = 0.0 Identities = 783/783 (100%), Positives = 783/783 (100%) Query: 1 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH 60 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH Sbjct: 1 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH 60 Query: 61 QGHLSGLVHTGQQLPIVPALRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDGQPPALPVT 120 QGHLSGLVHTGQQLPIVPALRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDGQPPALPVT Sbjct: 61 QGHLSGLVHTGQQLPIVPALRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDGQPPALPVT 120 Query: 121 TGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVALLWAGLGHL 180 TGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVALLWAGLGHL Sbjct: 121 TGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVALLWAGLGHL 180 Query: 181 GDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDP 240 GDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDP Sbjct: 181 GDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDP 240 Query: 241 MLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATA 300 MLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATA Sbjct: 241 MLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATA 300 Query: 301 PNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKE 360 PNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKE Sbjct: 301 PNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKE 360 Query: 361 EAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGD 420 EAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGD Sbjct: 361 EAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGD 420 Query: 421 NARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDG 480 NARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDG Sbjct: 421 NARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDG 480 Query: 481 HPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA 540 HPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA Sbjct: 481 HPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA 540 Query: 541 GTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGANRAPAALQ 600 GTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGANRAPAALQ Sbjct: 541 GTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGANRAPAALQ 600 Query: 601 VRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHAPACGRAHT 660 VRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHAPACGRAHT Sbjct: 601 VRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHAPACGRAHT 660 Query: 661 HAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPHTEVRLLHA 720 HAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPHTEVRLLHA Sbjct: 661 HAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPHTEVRLLHA 720 Query: 721 RSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGVGCAVLGAR 780 RSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGVGCAVLGAR Sbjct: 721 RSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGVGCAVLGAR 780 Query: 781 SEA 783 SEA Sbjct: 781 SEA 783 >gi|239751443 PREDICTED: hypothetical protein [Homo sapiens] Length = 783 Score = 1647 bits (4266), Expect = 0.0 Identities = 783/783 (100%), Positives = 783/783 (100%) Query: 1 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH 60 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH Sbjct: 1 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH 60 Query: 61 QGHLSGLVHTGQQLPIVPALRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDGQPPALPVT 120 QGHLSGLVHTGQQLPIVPALRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDGQPPALPVT Sbjct: 61 QGHLSGLVHTGQQLPIVPALRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDGQPPALPVT 120 Query: 121 TGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVALLWAGLGHL 180 TGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVALLWAGLGHL Sbjct: 121 TGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVALLWAGLGHL 180 Query: 181 GDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDP 240 GDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDP Sbjct: 181 GDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDP 240 Query: 241 MLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATA 300 MLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATA Sbjct: 241 MLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATA 300 Query: 301 PNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKE 360 PNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKE Sbjct: 301 PNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKE 360 Query: 361 EAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGD 420 EAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGD Sbjct: 361 EAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGD 420 Query: 421 NARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDG 480 NARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDG Sbjct: 421 NARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDG 480 Query: 481 HPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA 540 HPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA Sbjct: 481 HPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA 540 Query: 541 GTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGANRAPAALQ 600 GTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGANRAPAALQ Sbjct: 541 GTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGANRAPAALQ 600 Query: 601 VRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHAPACGRAHT 660 VRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHAPACGRAHT Sbjct: 601 VRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHAPACGRAHT 660 Query: 661 HAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPHTEVRLLHA 720 HAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPHTEVRLLHA Sbjct: 661 HAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPHTEVRLLHA 720 Query: 721 RSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGVGCAVLGAR 780 RSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGVGCAVLGAR Sbjct: 721 RSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGVGCAVLGAR 780 Query: 781 SEA 783 SEA Sbjct: 781 SEA 783 >gi|239745948 PREDICTED: hypothetical protein XP_002343622 [Homo sapiens] Length = 791 Score = 1640 bits (4247), Expect = 0.0 Identities = 783/791 (98%), Positives = 783/791 (98%), Gaps = 8/791 (1%) Query: 1 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH 60 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH Sbjct: 1 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH 60 Query: 61 QGHLSGLVHTGQQLPIVPA--------LRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDG 112 QGHLSGLVHTGQQLPIVPA LRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDG Sbjct: 61 QGHLSGLVHTGQQLPIVPATPQPLTQQLRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDG 120 Query: 113 QPPALPVTTGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVAL 172 QPPALPVTTGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVAL Sbjct: 121 QPPALPVTTGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVAL 180 Query: 173 LWAGLGHLGDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGG 232 LWAGLGHLGDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGG Sbjct: 181 LWAGLGHLGDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGG 240 Query: 233 CGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVA 292 CGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVA Sbjct: 241 CGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVA 300 Query: 293 LRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREA 352 LRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREA Sbjct: 301 LRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREA 360 Query: 353 DGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQD 412 DGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQD Sbjct: 361 DGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQD 420 Query: 413 DGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQA 472 DGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQA Sbjct: 421 DGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQA 480 Query: 473 HHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGP 532 HHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGP Sbjct: 481 HHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGP 540 Query: 533 GWDGGARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGA 592 GWDGGARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGA Sbjct: 541 GWDGGARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGA 600 Query: 593 NRAPAALQVRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHA 652 NRAPAALQVRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHA Sbjct: 601 NRAPAALQVRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHA 660 Query: 653 PACGRAHTHAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPH 712 PACGRAHTHAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPH Sbjct: 661 PACGRAHTHAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPH 720 Query: 713 TEVRLLHARSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGV 772 TEVRLLHARSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGV Sbjct: 721 TEVRLLHARSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGV 780 Query: 773 GCAVLGARSEA 783 GCAVLGARSEA Sbjct: 781 GCAVLGARSEA 791 >gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo sapiens] Length = 492 Score = 44.7 bits (104), Expect = 3e-04 Identities = 55/189 (29%), Positives = 73/189 (38%), Gaps = 31/189 (16%) Query: 459 GPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAG--GG 516 GP P Q+ Q+ H G + ++ + DSP P S W QL + Sbjct: 273 GPPPALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTPGSWWEQLTQASRVYAS 332 Query: 517 RGWEGRGAGRWARPGPGWDG-GARAGTQGLPLPGTEAEPGALGCSLSR------GPVPRQ 569 G EG RWA PG G A G Q PLP E PG G L R GP + Sbjct: 333 GGTEGFPLSRWA---PGRHGTAAEEGAQERPLPTDEMAPGR-GLWLGRLFGVPGGPAENE 388 Query: 570 GSLLSARVGWSLHHRYITSIQGANRAPAALQVRALRLHRNKACPALPAPTHLQAEPTR-- 627 L +R + ++ P + V L L + A P +P+P L+A R Sbjct: 389 NGALKSR-------------RPSSWLPPTVSV--LALVKRGAPPEMPSPQELEASAPRMV 433 Query: 628 -TFRLVREM 635 T R VR + Sbjct: 434 QTHRAVRAL 442 >gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo sapiens] Length = 902 Score = 44.7 bits (104), Expect = 3e-04 Identities = 55/189 (29%), Positives = 73/189 (38%), Gaps = 31/189 (16%) Query: 459 GPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAG--GG 516 GP P Q+ Q+ H G + ++ + DSP P S W QL + Sbjct: 683 GPPPALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTPGSWWEQLTQASRVYAS 742 Query: 517 RGWEGRGAGRWARPGPGWDG-GARAGTQGLPLPGTEAEPGALGCSLSR------GPVPRQ 569 G EG RWA PG G A G Q PLP E PG G L R GP + Sbjct: 743 GGTEGFPLSRWA---PGRHGTAAEEGAQERPLPTDEMAPGR-GLWLGRLFGVPGGPAENE 798 Query: 570 GSLLSARVGWSLHHRYITSIQGANRAPAALQVRALRLHRNKACPALPAPTHLQAEPTR-- 627 L +R + ++ P + V L L + A P +P+P L+A R Sbjct: 799 NGALKSR-------------RPSSWLPPTVSV--LALVKRGAPPEMPSPQELEASAPRMV 843 Query: 628 -TFRLVREM 635 T R VR + Sbjct: 844 QTHRAVRAL 852 >gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo sapiens] Length = 433 Score = 44.7 bits (104), Expect = 3e-04 Identities = 55/189 (29%), Positives = 73/189 (38%), Gaps = 31/189 (16%) Query: 459 GPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAG--GG 516 GP P Q+ Q+ H G + ++ + DSP P S W QL + Sbjct: 214 GPPPALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTPGSWWEQLTQASRVYAS 273 Query: 517 RGWEGRGAGRWARPGPGWDG-GARAGTQGLPLPGTEAEPGALGCSLSR------GPVPRQ 569 G EG RWA PG G A G Q PLP E PG G L R GP + Sbjct: 274 GGTEGFPLSRWA---PGRHGTAAEEGAQERPLPTDEMAPGR-GLWLGRLFGVPGGPAENE 329 Query: 570 GSLLSARVGWSLHHRYITSIQGANRAPAALQVRALRLHRNKACPALPAPTHLQAEPTR-- 627 L +R + ++ P + V L L + A P +P+P L+A R Sbjct: 330 NGALKSR-------------RPSSWLPPTVSV--LALVKRGAPPEMPSPQELEASAPRMV 374 Query: 628 -TFRLVREM 635 T R VR + Sbjct: 375 QTHRAVRAL 383 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 44.7 bits (104), Expect = 3e-04 Identities = 47/230 (20%), Positives = 83/230 (36%), Gaps = 32/230 (13%) Query: 314 DLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLH 373 ++ +G+ + E+ G +E EG++ + E +GE +EE G G E G Sbjct: 818 EVEEGKGEREEEEEEGEGEE----EEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873 Query: 374 HTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAP 433 G+ E EE +G +EE G G +GE +++GE + + G ++ Sbjct: 874 GEGEGEEEEGEGEGEEEGEGE------GEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEE 927 Query: 434 RPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALT 493 + +G + G E+EE + + +G +G G Sbjct: 928 GEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGE--------- 978 Query: 494 WDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARAGTQ 543 G+ + + G G G E G G G + G G + Sbjct: 979 -------------GEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEE 1015 Score = 38.1 bits (87), Expect = 0.032 Identities = 34/139 (24%), Positives = 54/139 (38%), Gaps = 2/139 (1%) Query: 339 EVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAP 398 E EG + E +G KEE GGEV G+ E EE +G +EE ++ Sbjct: 788 EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVE-EGKGEREEEEEEGEGEEEEGEGEEEE 846 Query: 399 FLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGV-EALAAAGWDMA 457 G +GE +++GE G+ + + + +G E G Sbjct: 847 GEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEE 906 Query: 458 LGPGPWEQEERQSQAHHQG 476 G G E+EE + + +G Sbjct: 907 EGEGEGEEEEGEGKGEEEG 925 Score = 37.4 bits (85), Expect = 0.054 Identities = 50/228 (21%), Positives = 81/228 (35%), Gaps = 52/228 (22%) Query: 188 EEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDPMLTPALV 247 EE+EG G EG+G+ ++ G G GEE + Sbjct: 829 EEEEGEGEEEEGEGE-----------------EEEGEGEEEEGEGKGEEEGEE------- 864 Query: 248 AATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQGDDQ 307 G G +EG + + E ++ G+G G G +G+++ Sbjct: 865 -----GEGEEEGEEGE----GEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915 Query: 308 PLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRGTG 367 +G+ + E G E EG+D + E +GE +EE G G Sbjct: 916 ---------EGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEG 966 Query: 368 GEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGE 415 E G+ E EE +G +EE + G +GE +++GE Sbjct: 967 EE-----EGEGEGEEGEGEGEEE-----EGEGEGEEEEGEEEGEEEGE 1004 Score = 33.9 bits (76), Expect = 0.60 Identities = 33/171 (19%), Positives = 69/171 (40%), Gaps = 12/171 (7%) Query: 316 YQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRG-------TGG 368 +Q +++ E G + PG+ + + ++ DGE+ ++E +G Sbjct: 669 WQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEME 728 Query: 369 EVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGL 428 E G G+ E EE ++EE G + G +GE +++GE K+ + A Sbjct: 729 EGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGER-EKEEGERKKEERAGKEEKG 787 Query: 429 QDDAPRPRAVTQVV----VQGVEALAAAGWDMALGPGPWEQEERQSQAHHQ 475 +++ + + + E G ++ G G E+EE + + + Sbjct: 788 EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE 838 Score = 32.0 bits (71), Expect = 2.3 Identities = 46/209 (22%), Positives = 78/209 (37%), Gaps = 40/209 (19%) Query: 188 EEDEGPGIG---GEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDPMLTP 244 EE+EG G G GEG+G+ G + G G G EE + Sbjct: 896 EEEEGEGEGEEEGEGEGEEEEGEG-----------KGEEEGEEGEGEGEEEEGEG----- 939 Query: 245 ALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQG 304 +G G EG +++ E + G+ G G G +G Sbjct: 940 ------EGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEG---EGEEEEGEGEG 990 Query: 305 DDQPLCIDDDLYQGQQQSHSEDH-PAPGPVVLPGQ---EVEGKDVSRQTREADGEQNPKE 360 +++ + +G+++ E+ G G+ EVEG++ + E +GE+ +E Sbjct: 991 EEE-----EGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEE 1045 Query: 361 EAPRGTGGEVGLHHTGKHEAEEAQGPQKE 389 G G E + + E EE +G +E Sbjct: 1046 REKEGEGEE---NRRNREEEEEEEGKYQE 1071 Score = 30.8 bits (68), Expect = 5.1 Identities = 52/250 (20%), Positives = 89/250 (35%), Gaps = 43/250 (17%) Query: 188 EEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDPMLTPALV 247 EE+EG G EG+G+ G + G G GEE + Sbjct: 836 EEEEGEGEEEEGEGEEEEGEG-----------KGEEEGEEGEGEEEGEEGE--------- 875 Query: 248 AATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQGDDQ 307 G G +E + + + E + G+G G G +G+++ Sbjct: 876 -----GEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEG------EGEEEEGEGKGEEE 924 Query: 308 PLCIDDDLYQGQQQSHSEDHPAPGPVV---LPGQEVEGKDVSRQTREADGEQNPKEEAPR 364 + + + + + ED G G+E EG+ + E +GE+ E Sbjct: 925 GEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEE 984 Query: 365 GTGGEVGLHHTGKHEAEE-AQGPQ------KEEYLGPQQAPFLGVLHKGEAGHQDDGEHK 417 GE G G+ E EE +G + +EE G + G +GE G +++GE + Sbjct: 985 EGEGE-GEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGE-GEEEEGEEE 1042 Query: 418 RGDNARPSHG 427 + + G Sbjct: 1043 GEEREKEGEG 1052 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 42.4 bits (98), Expect = 0.002 Identities = 123/469 (26%), Positives = 161/469 (34%), Gaps = 96/469 (20%) Query: 177 LGHLGDLGDDVEEDEGPGIGGEGD-GQRGVI-PGGTVVLLVAVSIHDDPHHPYGNGGGCG 234 +G GD GD E+ G G G RG P G LV G G G Sbjct: 1669 VGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTG---PGAREKGEPGDRG 1725 Query: 235 EEH-KDPMLTPALVAAT--------QGGPGPQEGTQQQQHDVDECHDKVHVG-DGTGGGH 284 +E + P P L A +G PGPQ G + E D+ G DG G Sbjct: 1726 QEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQ-GDPGVRGPAGEKGDRGPPGLDGRSGLD 1784 Query: 285 GPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKD 344 G AA + PN + D G + P+ GP LPG+ G+D Sbjct: 1785 GKPGAAGP------SGPNGAAGKAGDPGRDGLPGLRGEQGLPGPS-GPPGLPGKP--GED 1835 Query: 345 VSRQTREADGEQ-NPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEE----YLGPQQAPF 399 +GE +P E+ +G G+ +G E GP+ E LGPQ P Sbjct: 1836 GKPGLNGKNGEPGDPGEDGRKGEKGD-----SGASGREGRDGPKGERGAPGILGPQGPPG 1890 Query: 400 L----------------GVLHKGEAGHQDDGEHKRGDNARPSH-GLQDDAPRPRAVTQVV 442 L G KG+ G +G+ P GL+ + V +++ Sbjct: 1891 LPGPVGPPGQGFPGVPGGTGPKGDRGETGS----KGEQGLPGERGLRGEPGSVPNVDRLL 1946 Query: 443 -VQGVEALA----AAGWDMALGP---------GPWEQEERQSQAHHQGFVD--------- 479 G++A A WD + G GP Q +G + Sbjct: 1947 ETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKG 2006 Query: 480 --GHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGR--GAGRWARPGPGWD 535 G PG Q LAL PP P + +P G G GR G G RPG + Sbjct: 2007 DRGDPGPQGPPGLALGERGPPGPSGLAG----EPGKPGIPGLPGRAGGVGEAGRPGERGE 2062 Query: 536 GGARA-----GTQGLP-LPGTEAEPGALGCSLSRGPVPRQGSLLSARVG 578 G + G G P LPGT PG G +S V G LS G Sbjct: 2063 RGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVS---VDEPGPGLSGEQG 2108 Score = 41.6 bits (96), Expect = 0.003 Identities = 97/363 (26%), Positives = 129/363 (35%), Gaps = 63/363 (17%) Query: 226 PYGNGGGCGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGD----GTG 281 P G+ G GE+ DP G PGP G + + +V E D+ GD G Sbjct: 1605 PPGDSGPPGEKG-DP--------GRPGPPGPV-GPRGRDGEVGEKGDEGPPGDPGLPGKA 1654 Query: 282 GGHGPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSE--DHPAPGPVVLPGQE 339 G G A +R + +QGD +D G S D PGP PG+ Sbjct: 1655 GERGLR-GAPGVRGPVGEKGDQGDP-----GEDGRNGSPGSSGPKGDRGEPGPPGPPGRL 1708 Query: 340 VEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHT-GKHEAEEAQGPQKEEYLGPQQAP 398 V D RE + +E PRG G+ GL G+ E +GP GPQ P Sbjct: 1709 V---DTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPP-----GPQGDP 1760 Query: 399 FLGVLHKGEAGHQDDG-----EHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAG 453 GV +G AG + D + + G + +P G + A + G + L Sbjct: 1761 --GV--RGPAGEKGDRGPPGLDGRSGLDGKP--GAAGPSGPNGAAGKAGDPGRDGLPGLR 1814 Query: 454 WDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQA 513 + L PGP + G PG + L P P + G+ Sbjct: 1815 GEQGL-PGP----------SGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSG 1863 Query: 514 GGGRGWEGRGAGRWARPGPGWDGGARAGTQGLPLP------GTEAEPGALGCSLSRGPVP 567 GR EGR + R PG G G GLP P G PG G RG Sbjct: 1864 ASGR--EGRDGPKGERGAPGILG--PQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETG 1919 Query: 568 RQG 570 +G Sbjct: 1920 SKG 1922 Score = 41.2 bits (95), Expect = 0.004 Identities = 72/257 (28%), Positives = 89/257 (34%), Gaps = 29/257 (11%) Query: 328 PAP-GPVVLPGQEVEGKDVSRQTREADGEQ-NPKEEAPRGTGGEVGLHHTGKHEAEEAQG 385 P P GPV PG++ E D G+ +P E+ PRG G +G + Sbjct: 1432 PGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEA 1491 Query: 386 PQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSH-GLQDDAPRPRAVTQVVVQ 444 +K E P A G+ G AG +G P G Q + P V Sbjct: 1492 GEKGERGPPGPAGSRGL--PGVAGRPG----AKGPEGPPGPTGRQGEKGEPGRPGDPAVV 1545 Query: 445 GVEALAAAGWDMALGP-GPWEQEERQSQAHHQGFV-DGHPGSQARLWLALTWDSPPAPLQ 502 G G +GP GP Q + G V G PG + D P L Sbjct: 1546 GPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGD-----PGDRGPIGLT 1600 Query: 503 RSVWGQLQPQAGGGRGWEGRGAGRWARPGP----GWDGGA-RAGTQGLP----LPGTEAE 553 G+ P G E GR PGP G DG G +G P LPG E Sbjct: 1601 ----GRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGE 1656 Query: 554 PGALGCSLSRGPVPRQG 570 G G RGPV +G Sbjct: 1657 RGLRGAPGVRGPVGEKG 1673 Score = 37.4 bits (85), Expect = 0.054 Identities = 35/113 (30%), Positives = 44/113 (38%), Gaps = 11/113 (9%) Query: 460 PGPWEQEERQSQAHHQGF--VDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGR 517 PGP + +GF DG PGS R +P P + G P G R Sbjct: 1283 PGPQGPPGSATAKGERGFPGADGRPGSPGRA------GNPGTPGAPGLKGS--PGLPGPR 1334 Query: 518 GWEGRGAGRWARPGPGWDGGARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQG 570 G G R + PG G G +G LPG + +PG G RGP+ G Sbjct: 1335 GDPGERGPRGPKGEPGAPGQVIGG-EGPGLPGRKGDPGPSGPPGPRGPLGDPG 1386 Score = 35.0 bits (79), Expect = 0.27 Identities = 64/238 (26%), Positives = 82/238 (34%), Gaps = 61/238 (25%) Query: 336 PGQEVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQ 395 PGQ + G+ R+ D P P G G +G GP+ GP Sbjct: 1352 PGQVIGGEGPGLPGRKGD----PGPSGPPGPRGPLG-----------DPGPR-----GPP 1391 Query: 396 QAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAA-GW 454 P G KG+ G RG+ P G AP G+ L + G Sbjct: 1392 GLP--GTAMKGDKGD-------RGERGPPGPGEGGIAPGE--------PGLPGLPGSPGP 1434 Query: 455 DMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAG 514 +GP + E+ S+ G + G PGS P P G + P+ Sbjct: 1435 QGPVGPPGKKGEKGDSEDGAPG-LPGQPGSPGE-------QGPRGPP-----GAIGPK-- 1479 Query: 515 GGRGWEGR--GAGRWARPGPGWDGGARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQG 570 G RG+ G AG GP G+R LPG PGA G GP RQG Sbjct: 1480 GDRGFPGPLGEAGEKGERGPPGPAGSRG------LPGVAGRPGAKGPEGPPGPTGRQG 1531 Score = 34.7 bits (78), Expect = 0.35 Identities = 66/261 (25%), Positives = 86/261 (32%), Gaps = 43/261 (16%) Query: 327 HPAPGPVVLPGQE-VEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQG 385 H PGP PG G + GE P G G VGL Sbjct: 2182 HGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGP---------- 2231 Query: 386 PQKEEYLGPQQAPFL----GVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQV 441 P +GPQ +P L G K A +D K GD P P P V Sbjct: 2232 PGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGP-----V 2286 Query: 442 VVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPL 501 +G A +G P + E+ + G + G PG++ L P P Sbjct: 2287 GPKGEPGPTGAPGQAVVGL-PGAKGEKGAPGGLAGDLVGEPGAKGDRGL-------PGPR 2338 Query: 502 -QRSVWGQL----------QPQAGGGRGWEGR-GAGRWARPGPGWDGGARAGTQGLPLPG 549 ++ G+ Q A G +G++G G G PGP G + L LPG Sbjct: 2339 GEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGD---LGLPG 2395 Query: 550 TEAEPGALGCSLSRGPVPRQG 570 PG +G GP G Sbjct: 2396 LPGAPGVVGFPGQTGPRGEMG 2416 Score = 32.7 bits (73), Expect = 1.3 Identities = 88/333 (26%), Positives = 112/333 (33%), Gaps = 57/333 (17%) Query: 330 PGPVVLPGQEVEGKDVSRQTREAD-GEQNPK-EEAPRGTGGEVGLHHT-------GKHEA 380 PG +PG V R + GE+ K E +G G GL T G + Sbjct: 2036 PGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVS 2095 Query: 381 EEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHK--------RGDNARPSHGLQDDA 432 + GP GP KGE G D K +GD P QD Sbjct: 2096 VDEPGPGLSGEQGPPGLKGA----KGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGN 2151 Query: 433 PR-PRAVTQVVVQGVEALAAA-GWDMALG----PGPWEQEERQSQAHHQG--FVDGHPGS 484 P P +G L G +G PGP A QG + G PG Sbjct: 2152 PGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGE 2211 Query: 485 QARLWLALTWDS-------PPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPG-PGWDG 536 LT + PP P G + PQ G G G+ G +PG PG DG Sbjct: 2212 TGPPGRGLTGPTGAVGLPGPPGPS-----GLVGPQ--GSPGLPGQ-VGETGKPGAPGRDG 2263 Query: 537 GA-RAGTQGLP-LPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGANR 594 + + G +G P +PG+ PG +G GP G A VG + +G Sbjct: 2264 ASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPG---QAVVG-------LPGAKGEKG 2313 Query: 595 APAALQVRALRLHRNKACPALPAPTHLQAEPTR 627 AP L + K LP P + E R Sbjct: 2314 APGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGR 2346 >gi|27894378 chloride intracellular channel 6 [Homo sapiens] Length = 686 Score = 41.2 bits (95), Expect = 0.004 Identities = 97/386 (25%), Positives = 128/386 (33%), Gaps = 80/386 (20%) Query: 204 GVIPGGTVVLLVAVSIHDDPHHPYGNGGGC----GEEHKDPMLTPALVAATQGGPGPQEG 259 GV PG V + + P P GG G E + A GG GP G Sbjct: 9 GVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRG 68 Query: 260 TQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQ 319 + + H + +G G A P G++ G Sbjct: 69 PEAEARGTRGAHGETEAEEGAPEG--------------AEVPQGGEET---------SGA 105 Query: 320 QQSHSEDHPAPGPVVLPGQEV--EGKDVSRQTREADGEQNPKEEAPRGT-GGEVGLHHTG 376 QQ P G P E E +D + R+ + EQ P E P G+ GE G Sbjct: 106 QQVEGAS-PGRGAQGEPRGEAQREPEDSAAPERQEEAEQRP--EVPEGSASGEAG----- 157 Query: 377 KHEAEEAQGPQKE--EYLGP-----QQAPFLG--VLHKGEAGHQDDGEHKRGDNARPSHG 427 ++ +A+GP + E GP + +G V +G AG D E GDN + Sbjct: 158 --DSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGP 215 Query: 428 LQD------------DAPRPRAVTQVVVQG-----VEALAAAGWDMALGPGPWEQEERQS 470 D DA P A V +G VEA AG + G + E + Sbjct: 216 AGDSVDAEGRVGDSVDAEGP-AGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEG 274 Query: 471 QAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARP 530 A +G G R+ Q+S G L PQA G AGR P Sbjct: 275 PAGDSMDAEGPAGRARRV---------SGEPQQSGDGSLSPQAEAIEVAAGESAGR--SP 323 Query: 531 GP-GWDGGARAGTQGLPLPGTEAEPG 555 G WD A G+ EA PG Sbjct: 324 GELAWDAAEEAEVPGVK-GSEEAAPG 348 Score = 31.2 bits (69), Expect = 3.9 Identities = 57/234 (24%), Positives = 89/234 (38%), Gaps = 24/234 (10%) Query: 337 GQEVEGKDVSRQTREADGEQNPKEEA--PRGTGGEVGLHHTGKHEAE-------EAQGP- 386 G V+ + + + +A+G EA P G G E G+ EAE +A+GP Sbjct: 227 GDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPA 286 Query: 387 -QKEEYLG-PQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQ 444 + G PQQ+ + + EA GE + ++A P Sbjct: 287 GRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAA 346 Query: 445 GVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRS 504 +A A AG D +G GP +QE + + + +G +A + DS +P + Sbjct: 347 PGDARADAGEDR-VGDGP-QQEPGEDEERRERSPEGPREEEAAGGEEESPDS--SPHGEA 402 Query: 505 VWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARAGTQGLPLPGTEAEPGALG 558 G +P+A + + A GP G A G G +EP ALG Sbjct: 403 SRGAAEPEA--------QLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALG 448 Score = 30.8 bits (68), Expect = 5.1 Identities = 73/331 (22%), Positives = 107/331 (32%), Gaps = 65/331 (19%) Query: 155 DGLIAHAPGGVHVPLVALLWAGLGHLGDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLL 214 D + A P G V L + G GD V+ + G + +G G +V Sbjct: 188 DSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAG----DSVDAE 243 Query: 215 VAVSIHDDPHHPYGNGGGCGEEHKDPMLTPALVAATQGGPGPQ------EGTQQQQHD-- 266 V + P G+G G D + + GP G QQ D Sbjct: 244 GRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGS 303 Query: 267 VDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSED 326 + + + V G G P A +G ++ D G ED Sbjct: 304 LSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAG------ED 357 Query: 327 HPAPGPVVLPGQEVEGKDVS----RQTREADGEQNPKEEAPRG---TGGEVGLHHTGKHE 379 GP PG++ E ++ S R+ A GE+ + +P G G H Sbjct: 358 RVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHL 417 Query: 380 AEEAQGPQKEEYLGPQQAPFLGVLHKGEA----GHQDDGEHKRGDNARPSHGLQDDAPRP 435 AEE GP + GEA G ++DGE A P Sbjct: 418 AEE----------GPAEG-------SGEAARVNGRREDGE----------------ASEP 444 Query: 436 RAVTQVVVQGVEALAAAGWD-MALGPGPWEQ 465 RA+ Q + AG+D ++G P+ Q Sbjct: 445 RALGQ--EHDITLFVKAGYDGESIGNCPFSQ 473 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 40.8 bits (94), Expect = 0.005 Identities = 70/338 (20%), Positives = 118/338 (34%), Gaps = 48/338 (14%) Query: 254 PGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVAL--RAALATAPNQGDDQPLCI 311 P + Q + DV+ + V + G P A ++ +G+D+P Sbjct: 1877 PEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESE 1936 Query: 312 DDDLYQGQQQSH-SEDHPAPGPVVLPGQE-----------VEGKDVSRQTREADGEQNPK 359 + + ++ + +E P V+ QE VE +V +T+EA+GE P+ Sbjct: 1937 GAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPE 1996 Query: 360 E---EAPRGTG-----------GEVGLHHTGKHEAEEAQ----GPQKEEYLGPQQAPFLG 401 EAP G G+ K E EEAQ QK E ++ + Sbjct: 1997 SEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVE 2056 Query: 402 VLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPG 461 E + +GE + + DA Q +GVEA A G Sbjct: 2057 APEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGI 2116 Query: 462 PWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEG 521 + E ++Q +G +A+ + G+ QP++ G E Sbjct: 2117 EAPETEGEAQPESEGIEAPEAEGEAQ-------PESEGVEAQDAEGEAQPES---EGIEA 2166 Query: 522 RGAGRWARP------GPGWDGGARAGTQGLPLPGTEAE 553 + A A+P P +G A+ ++G+ P E E Sbjct: 2167 QEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGE 2204 Score = 31.6 bits (70), Expect = 3.0 Identities = 70/319 (21%), Positives = 103/319 (32%), Gaps = 78/319 (24%) Query: 161 APGGVHVPLVALLWAGLGHLGDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIH 220 APG H + G G LG + + G G +G+G + ++ Sbjct: 1709 APGKTHTDPTSTRTVQ-GAEGGLGPGLSQGPGVDEGEDGEGSQ------------RLNRD 1755 Query: 221 DDPHHPYGNGGGCGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGT 280 DP G +E + A ++ G QEG + ++ G G Sbjct: 1756 KDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEG--------EGISERGETG-GQ 1806 Query: 281 GGGHGPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEV 340 G GH A A P Q D I+ +G+ Q SE AP E Sbjct: 1807 GSGHEDNLQGEAA-AGGDQDPGQSDGAE-GIEAPEAEGEAQPESEGVEAP--------EA 1856 Query: 341 EGKDVSRQTREADGEQNPKE---EAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQA 397 EG +EA+GE P+ EAP G + E+E+ + P+ E + P+ Sbjct: 1857 EG-----DAQEAEGEAQPESEDVEAPEAEG-------EAQPESEDVETPEAEWEVQPE-- 1902 Query: 398 PFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMA 457 S G +AP Q + VEAL G D Sbjct: 1903 ---------------------------SEGA--EAPEAEKEAQPETESVEALETEGEDEP 1933 Query: 458 LGPGPWEQEERQSQAHHQG 476 G QE ++ +G Sbjct: 1934 ESEGAEAQEAEEAAQEAEG 1952 Score = 30.8 bits (68), Expect = 5.1 Identities = 25/109 (22%), Positives = 39/109 (35%), Gaps = 14/109 (12%) Query: 317 QGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTG 376 +G + +E+ P P + E EG+ E GE+ + G G Sbjct: 2210 EGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDG--------Q 2261 Query: 377 KHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPS 425 EA E+ P E+ P +P G+ HQ G ++R S Sbjct: 2262 SEEASESSSPVPEDRPTPPPSP------GGDTPHQRPGSQTGPSSSRAS 2304 >gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] Length = 1714 Score = 40.0 bits (92), Expect = 0.008 Identities = 71/267 (26%), Positives = 96/267 (35%), Gaps = 53/267 (19%) Query: 331 GPVVLPGQE-VEGKDVSRQTREADGEQNPKEE-------APRGTGGEVGL----HHTGKH 378 GPV LPG+ + G + R + G P+ E P G G +G H G Sbjct: 855 GPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGAR 914 Query: 379 EAEEAQGPQKEE-YLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRA 437 +QGP+ + GP G+L GE G Q K R HGL P Sbjct: 915 GPPGSQGPKGQRGSRGPD-----GLL--GEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGE 967 Query: 438 VTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFV--DGHPGSQARLWLALTWD 495 G++ L + D L PG Q G + +G PG++ L Sbjct: 968 RGFQGKPGLQGLPGSTGDRGL-PGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGL----- 1021 Query: 496 SPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPG-------PGWDG-GARAGTQGLP- 546 Q +P A G G G G PG PG +G + G +G+P Sbjct: 1022 ------------QGEPGAKGDVGTAG-SVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPG 1068 Query: 547 ---LPGTEAEPGALGCSLSRGPVPRQG 570 LPG + E G +G GP+ R G Sbjct: 1069 GRGLPGEDGEKGEMGLPGIIGPLGRSG 1095 Score = 35.8 bits (81), Expect = 0.16 Identities = 67/273 (24%), Positives = 91/273 (33%), Gaps = 42/273 (15%) Query: 303 QGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEA 362 QG++ P+ +L + PGP L G+ + ++ + E Sbjct: 806 QGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIG----------ETG 855 Query: 363 PRGTGGEVGLHHTGKHEAEEAQ----GPQKEE----YLGPQQAPF-LGVL----HKGEAG 409 P G GEVG+ + + E GPQ E+ Y GP P +G L H G G Sbjct: 856 PVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARG 915 Query: 410 HQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQ 469 K +R GL + QG++ D GP + Sbjct: 916 PPGSQGPKGQRGSRGPDGLLGE------------QGIQGAKGEKGDQGKR-GPHGLIGKT 962 Query: 470 SQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGR----GWEGRGAG 525 +GF G PG Q P P R + G + P G G EG +G Sbjct: 963 GNPGERGF-QGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGE-SG 1020 Query: 526 RWARPGPGWDGGARAGTQGLPLPGTEAEPGALG 558 PG D G G PG EPGA G Sbjct: 1021 LQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPG 1053 >gi|156616290 collagen type VI alpha 6 [Homo sapiens] Length = 2263 Score = 39.7 bits (91), Expect = 0.011 Identities = 76/292 (26%), Positives = 104/292 (35%), Gaps = 61/292 (20%) Query: 277 GDGTGGGHGPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLP 336 GDGT G GP R ++G Y G++ E APGPV Sbjct: 1393 GDGTMGDPGPP----GKRGPPGFKGSEG-----------YLGEEGIAGE-RGAPGPVGEQ 1436 Query: 337 GQEVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQ 396 G T+ G + PK RG G+ G G++ + G Q + L ++ Sbjct: 1437 G-----------TKGCYGTKGPKGN--RGLNGQEG--EVGENGIDGLNGEQGDNGLPGRK 1481 Query: 397 APFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAA---- 452 KG+ G Q + R + GL+ D P + + +G L Sbjct: 1482 G------EKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSI--EGPTGLKGERGRQ 1533 Query: 453 ---GWDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVW--G 507 GW GP R++ AH + GH G Q + P L+ S+ G Sbjct: 1534 GRRGWP---GPPGTPGSRRKTAAHGRR---GHTGPQGTAGIP-----GPDGLEGSLGLKG 1582 Query: 508 QLQPQAGGGRGWEGRGAGRWARPGPGWDGGARAGTQG-LPLPGTEAEPGALG 558 P+ G E G G GP GG AG QG L G + EPG LG Sbjct: 1583 PQGPRGEAGVKGEKGGVGSKGPQGPPGPGG-EAGNQGRLGSQGNKGEPGDLG 1633 >gi|91208420 bassoon protein [Homo sapiens] Length = 3926 Score = 39.7 bits (91), Expect = 0.011 Identities = 56/235 (23%), Positives = 76/235 (32%), Gaps = 38/235 (16%) Query: 361 EAPRGTGGEVGLHHTGKHEAEEAQ--GPQKEEYLGPQQAPFLGVLHKGEAG---HQDDGE 415 + PR + HH G + +Q GP + Y + P G+ E G H E Sbjct: 3585 DKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKE 3644 Query: 416 HKRGDNARPSHGLQDDAPRPRAV-------------TQVVVQGVEALAAAGWDMALGPGP 462 H+ GD+ R S + P RA A+ G Sbjct: 3645 HRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAE 3704 Query: 463 WEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGR 522 + Q R S A+H D GS+ S PA LQ Q QPQ Sbjct: 3705 YSQPSRASSAYHHA-SDSKKGSRQA-------HSGPAALQSKAEPQAQPQL--------- 3747 Query: 523 GAGRWARPGPGWDGGARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARV 577 GR A PGP ++ +P +P G P Q +L AR+ Sbjct: 3748 -QGRQAAPGP--QQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARL 3799 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 39.7 bits (91), Expect = 0.011 Identities = 68/248 (27%), Positives = 90/248 (36%), Gaps = 53/248 (21%) Query: 317 QGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQN-PKEEAPRGTGGEVGLHHT 375 +G++ ED A GP PG G R R G+ P +E +G G+ G Sbjct: 1326 KGEKGEQGEDGKAEGPPGPPGDR--GPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQ 1383 Query: 376 GKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRP 435 H P + GP+ + KG G + R GLQ P P Sbjct: 1384 PGH-------PGPRGWPGPKGS-------KGAEGPKGKQGKAGAPGRRGVQGLQG-LPGP 1428 Query: 436 RAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFV--DGHPGSQARLWLALT 493 R V V QG+E +A GP R QA QG DG PG Sbjct: 1429 RGV--VGRQGLEGIA----------GPDGLPGRDGQAGQQGEQGDDGDPGPMG------- 1469 Query: 494 WDSPPAPLQRSVWGQLQPQAGGGRGWEGRGA--GRWARPGPGWDGGARAGTQGLP-LPGT 550 PA + + P A G G++G G+ PG + GT+G LPG Sbjct: 1470 ----PAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPG-------KRGTEGRTGLPGN 1518 Query: 551 EAEPGALG 558 + EPG+ G Sbjct: 1519 QGEPGSKG 1526 Score = 32.3 bits (72), Expect = 1.7 Identities = 65/247 (26%), Positives = 87/247 (35%), Gaps = 56/247 (22%) Query: 358 PKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEY-LGPQQAPFLGVLHKGEAGHQDDGEH 416 P + P G G+ G G GP+ +E +GP AP L +G+ G Sbjct: 918 PGDNGPEGMKGKPGAR--GLPGPRGQLGPEGDEGPMGPPGAPGL----EGQPG------- 964 Query: 417 KRGDNARPS----HGLQDDAPRPRAVTQ------VVVQGVEALAAAGWDMALGPGPWEQE 466 ++G RP G D RP V + + + G + D + P Sbjct: 965 RKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPG 1024 Query: 467 ERQSQAHHQGF-----VDGHPGSQARLWLALTWDSPPA----PLQRSVWGQLQPQ----- 512 + S H G G PG Q PP P R G+ P+ Sbjct: 1025 PKGSMGH-PGMPGGMGTPGEPGPQG----------PPGSRGPPGMRGAKGRRGPRGPDGP 1073 Query: 513 AG--GGRGWEGRGA--GRWARPGPGWDGGARA--GTQGLP-LPGTEAEPGALGCSLSRGP 565 AG G RG +G GR RPG G R G++G P +PG PG G GP Sbjct: 1074 AGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGP 1133 Query: 566 VPRQGSL 572 QG + Sbjct: 1134 QGPQGPI 1140 Score = 32.0 bits (71), Expect = 2.3 Identities = 95/362 (26%), Positives = 124/362 (34%), Gaps = 70/362 (19%) Query: 228 GNGGGCGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGP- 286 G G GE+ M+ P V +G G H + G GT G GP Sbjct: 1003 GEPGIVGEKGDRGMMGPPGVPGPKGSMG---------------HPGMPGGMGTPGEPGPQ 1047 Query: 287 ----ACAAVALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPG----Q 338 + +R A +G D P G+Q S P PGP PG Q Sbjct: 1048 GPPGSRGPPGMRGAKGRRGPRGPDGPA--------GEQGSRGLKGP-PGPQGRPGRPGQQ 1098 Query: 339 EVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAP 398 V G+ +R G P P GT G G G + GP E +GP+ P Sbjct: 1099 GVAGERGHLGSRGFPGIPGPS--GPPGTKGLPG--EPGPQGPQGPIGPPGE--MGPKGPP 1152 Query: 399 FLGVLHK----GEAGHQDDGEHKRGDNARPSH-GLQDDAPRPRAVTQVVVQGVEALAAAG 453 G + + GEAG + D G P GL P G + L Sbjct: 1153 --GAVGEPGLPGEAGMKGD----LGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDR 1206 Query: 454 WDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQA 513 D PGP + + Q G DG PG +T P + + A Sbjct: 1207 GD----PGPDGEHGEKGQEGLMG-EDGPPGPPG-----VTGVRGPEGKSGKQGEKGRTGA 1256 Query: 514 GGGRGWEGRGAGRWARPG----PGWDG--GARA--GTQGLP-LPGTEAEPGALGCSLSRG 564 G +G++G+ G PG PG G G+R G G P G + EPG G +G Sbjct: 1257 KGAKGYQGQ-LGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKG 1315 Query: 565 PV 566 V Sbjct: 1316 IV 1317 Score = 30.8 bits (68), Expect = 5.1 Identities = 26/69 (37%), Positives = 31/69 (44%), Gaps = 7/69 (10%) Query: 508 QLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA--GTQGLP----LPGTEAEPGALGCSL 561 Q QP G G +G GR PGP D G + G GLP LPG++ E G G Sbjct: 723 QGQPGPEGSPGAKGY-PGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPG 781 Query: 562 SRGPVPRQG 570 RG + G Sbjct: 782 KRGKMGMPG 790 >gi|154759255 collagen, type XXVIII precursor [Homo sapiens] Length = 1125 Score = 39.7 bits (91), Expect = 0.011 Identities = 64/231 (27%), Positives = 85/231 (36%), Gaps = 69/231 (29%) Query: 357 NPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDG-- 414 +P + P GT G G+ +G + GP+ P G KGEAG + G Sbjct: 246 DPGDPGPPGTHGNPGI-----------KGER-----GPKGNP--GNAQKGEAGERGPGGI 287 Query: 415 ------EHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEER 468 + +RG+ +P G++ D P +G++ + D PGP Sbjct: 288 PGYKGDKGERGECGKP--GIKGDKGSPGPYGPKGPRGIQGITGPPGD----PGP------ 335 Query: 469 QSQAHHQGFVD--GHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGR---- 522 +GF G PG + SP AP G Q G RG EGR Sbjct: 336 ------KGFQGNKGEPGPPG------PYGSPGAP------GIGQQGIKGERGQEGRPGAP 377 Query: 523 ---GAGRWARPGPGWDGGARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQG 570 G G +PGP G G +GLP E PG G S GP QG Sbjct: 378 GPIGVGEPGQPGPRGPEGV-PGERGLP---GEGFPGPKGEKGSEGPTGPQG 424 >gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens] Length = 1597 Score = 39.3 bits (90), Expect = 0.014 Identities = 43/181 (23%), Positives = 64/181 (35%), Gaps = 20/181 (11%) Query: 296 ALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGE 355 +L Q +++ D+ Q + S E+HPA E + S GE Sbjct: 158 SLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPA---------ETNQNEGSESGTIRQGE 208 Query: 356 QNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGE 415 + P EE G L H + + E QG Q+ + G G L + GE Sbjct: 209 ELPPEELQESQG----LLHPQEVQVLEEQGQQEAGFRGE------GTLREDVCADGLLGE 258 Query: 416 HKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQ 475 + + G Q + QG E + G L G WEQE+ + +A Q Sbjct: 259 EQMIEQVNDEKGEQKQKQEQVQDVMLGRQG-ERMGLTGEPEGLNDGEWEQEDMERKAQGQ 317 Query: 476 G 476 G Sbjct: 318 G 318 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 38.9 bits (89), Expect = 0.019 Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 25/140 (17%) Query: 272 DKVHVGDGTGGGHGP-------ACAAVA-LRAALATAPNQGDDQP----LCIDDDLYQGQ 319 D+ +G G G P A +A++ L +LA P + P L + + Sbjct: 250 DRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPA 309 Query: 320 QQSHSEDHPA----PGPVVLPGQEVEGKDV-SRQTREADGEQNPKEEAPRGTGG-----E 369 Q ++D P+ P P PG+E G V + +GE++ E+APRG+ G E Sbjct: 310 AQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPE 369 Query: 370 VG---LHHTGKHEAEEAQGP 386 VG G+ EEAQGP Sbjct: 370 VGEDAPQRLGEEPEEEAQGP 389 >gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like [Homo sapiens] Length = 484 Score = 38.5 bits (88), Expect = 0.024 Identities = 42/181 (23%), Positives = 64/181 (35%), Gaps = 20/181 (11%) Query: 296 ALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGE 355 +L Q +++ D+ Q + S E+HPA E + + GE Sbjct: 158 SLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPA---------ETNQNEGAESGTIRQGE 208 Query: 356 QNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGE 415 + P EE G L H + + E QG Q+ + G G L + GE Sbjct: 209 ELPSEELQESQG----LLHPQEVQVLEEQGQQEAGFRGE------GTLREDVCADGLLGE 258 Query: 416 HKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQ 475 + + G Q + QG E + G L G WEQE+ + +A Q Sbjct: 259 EQMIEQVNDEKGEQKQKQEQVQDVMLGRQG-ERMGLTGEPEGLNDGEWEQEDMERKAQGQ 317 Query: 476 G 476 G Sbjct: 318 G 318 >gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] Length = 957 Score = 38.5 bits (88), Expect = 0.024 Identities = 77/291 (26%), Positives = 104/291 (35%), Gaps = 52/291 (17%) Query: 306 DQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGK----------DVSRQTREADGE 355 D L IDD QQ + HP G +++ GQ GK DV + D E Sbjct: 360 DVTLYIDD-----QQIENKPLHPVLG-ILINGQTQIGKYSGKEETVQFDVQKLRIYCDPE 413 Query: 356 QNPKEEAPR--GTGGEV--GLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQ 411 QN +E A G GE G G A P K GP+ P L G G+ Sbjct: 414 QNNRETACEIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGL----PGNPGYP 469 Query: 412 DDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQ 471 + G + +P G Q A P +QG L PG + R Sbjct: 470 G----QPGQDGKP--GYQGIAGTPGVPGSPGIQGARGL----------PGYKGEPGRDGD 513 Query: 472 AHHQGF-----VDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQ----PQAGGGRGWEGR 522 +G + G PGS+ + SP ++ G+ P G G GR Sbjct: 514 KGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGR 573 Query: 523 GAGRWARPGPGWDGGARAGTQGLP-LPGTEAEPGALGCSLSRGPVPRQGSL 572 PG+ G AG+ G P GT EPG G +RG + ++G + Sbjct: 574 HGKDGLMGSPGFKG--EAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEI 622 >gi|169214011 PREDICTED: hypothetical protein [Homo sapiens] Length = 186 Score = 38.1 bits (87), Expect = 0.032 Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 3/78 (3%) Query: 500 PLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARAG--TQGLPLPGTEAEPGAL 557 P R W +++ + G GRG RG GR +P G GG AG T + LP P Sbjct: 103 PRGRGGW-EVRHRPGWGRGLHRRGLGRAEQPERGRAGGPGAGPRTPPMTLPSPPTLPAQD 161 Query: 558 GCSLSRGPVPRQGSLLSA 575 G +RGP P + L+A Sbjct: 162 GKKEARGPEPPLETPLAA 179 >gi|239756028 PREDICTED: hypothetical protein [Homo sapiens] Length = 255 Score = 38.1 bits (87), Expect = 0.032 Identities = 33/109 (30%), Positives = 40/109 (36%), Gaps = 16/109 (14%) Query: 466 EERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAG 525 EER + G G +A +W PP P + +A GGR W GRGAG Sbjct: 12 EERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVL------KARGGRAWGGRGAG 65 Query: 526 RWARP----------GPGWDGGARAGTQGLPLPGTEAEPGALGCSLSRG 564 + P GP GG R LP A P G S+G Sbjct: 66 SQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG 114 >gi|113428768 PREDICTED: hypothetical protein [Homo sapiens] Length = 186 Score = 38.1 bits (87), Expect = 0.032 Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 3/78 (3%) Query: 500 PLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARAG--TQGLPLPGTEAEPGAL 557 P R W +++ + G GRG RG GR +P G GG AG T + LP P Sbjct: 103 PRGRGGW-EVRHRPGWGRGLHRRGLGRAEQPERGRAGGPGAGPRTPPMTLPSPPTLPAQD 161 Query: 558 GCSLSRGPVPRQGSLLSA 575 G +RGP P + L+A Sbjct: 162 GKKEARGPEPPLETPLAA 179 >gi|113428351 PREDICTED: hypothetical protein [Homo sapiens] Length = 186 Score = 38.1 bits (87), Expect = 0.032 Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 3/78 (3%) Query: 500 PLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARAG--TQGLPLPGTEAEPGAL 557 P R W +++ + G GRG RG GR +P G GG AG T + LP P Sbjct: 103 PRGRGGW-EVRHRPGWGRGLHRRGLGRAEQPERGRAGGPGAGPRTPPMTLPSPPTLPAQD 161 Query: 558 GCSLSRGPVPRQGSLLSA 575 G +RGP P + L+A Sbjct: 162 GKKEARGPEPPLETPLAA 179 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 37.4 bits (85), Expect = 0.054 Identities = 70/244 (28%), Positives = 84/244 (34%), Gaps = 29/244 (11%) Query: 330 PGPVVLPGQEVEGKDVSRQTREADGEQNPKE-EAPRGTGGEVGLHHT-GKHEAEEAQGPQ 387 PGP G+ G S+ A GE P + P G GE G G+ GP Sbjct: 427 PGPKGNSGEP--GAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPP 484 Query: 388 KEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVE 447 E GP F G G AG + + G +A RP +G+ Sbjct: 485 GERG-GPGSRGFPGA--DGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLT 541 Query: 448 ALAAA-GWDMALGP-GPWEQEERQSQ-----AHHQGFVDGHPGSQARLWLALTWDSPPAP 500 + G D GP GP Q+ R A Q V G PG + P Sbjct: 542 GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAA------GEPGKA 595 Query: 501 LQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA--GTQGLP----LPGTEAEP 554 +R V G P A G G +G AG PGP G R G G P LPG P Sbjct: 596 GERGVPGP--PGAVGPAGKDGE-AGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPP 652 Query: 555 GALG 558 G G Sbjct: 653 GEAG 656 Score = 33.1 bits (74), Expect = 1.0 Identities = 71/237 (29%), Positives = 86/237 (36%), Gaps = 44/237 (18%) Query: 358 PKEEAPRGTGGEVGLHHT-------GKHEAEEAQGPQKEEYLGPQQAP-FLGVLH-KGEA 408 P + PRG GE G G A A GP GP P F G + KGEA Sbjct: 298 PGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPT--GPAGPPGFPGAVGAKGEA 355 Query: 409 GHQ-----DDGEHKRGDNARPSH-GLQDDAPRPRAVTQVVVQGVEAL----AAAGWDMAL 458 G Q + + RG+ P G A P A Q +G A G+ A Sbjct: 356 GPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415 Query: 459 GP-GPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGR 517 GP GP + G G PGS+ P P+ G P G Sbjct: 416 GPSGPQGPGGPPGPKGNSG-EPGAPGSKGDTGAK----GEPGPV-----GVQGPP--GPA 463 Query: 518 GWEGRGAGRWARPGP-GWDG--GARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQGS 571 G EG+ R PGP G G G R G PG+ PGA G + +GP +GS Sbjct: 464 GEEGKRGAR-GEPGPTGLPGPPGERGG------PGSRGFPGADGVAGPKGPAGERGS 513 Score = 32.7 bits (73), Expect = 1.3 Identities = 91/364 (25%), Positives = 109/364 (29%), Gaps = 77/364 (21%) Query: 223 PHHPYGNGGGCGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGG 282 P P G G GE + P + +G PG + +D G G Sbjct: 282 PAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDG---------ATGAAG 332 Query: 283 GHGPACAA--VALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHP-----APGPVVL 335 GP A A+ G P + G Q E P A GP Sbjct: 333 PPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSE-----GPQGVRGEPGPPGPAGAAGPAGN 387 Query: 336 PGQE-------------VEGKDVSRQTREADGEQNPK-EEAPRGTGGEVGLHHT-GKHEA 380 PG + + G R G Q P P+G GE G + G A Sbjct: 388 PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA 447 Query: 381 EEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQ 440 + GP +G Q P G AG E KRG P P R Sbjct: 448 KGEPGP-----VGVQGPP-------GPAGE----EGKRGARGEPGPTGLPGPPGERG--- 488 Query: 441 VVVQGVEALAAAGWDMALGP-GPWEQEERQSQAHHQGFVD--GHPGSQARLWLALTWDSP 497 G + G D GP GP + A +G G PG SP Sbjct: 489 ----GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSP 544 Query: 498 PAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGAR--AGTQGLPLP-GTEAEP 554 +P G P AG+ RPGP GAR AG G P P G EP Sbjct: 545 GSPGPDGKTGPPGP------------AGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEP 592 Query: 555 GALG 558 G G Sbjct: 593 GKAG 596 Score = 31.2 bits (69), Expect = 3.9 Identities = 62/248 (25%), Positives = 78/248 (31%), Gaps = 20/248 (8%) Query: 330 PGPVVLPGQEVEGKDVSRQTREADGEQNPK----EEAPRGTGGEVGLHHTGKHEAEEAQG 385 PGP G GKD + G P E+ P G+ G GL E + Sbjct: 601 PGPPGAVGPA--GKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGK- 657 Query: 386 PQKEEYLGPQQAPFLGVLH-----KGEAGHQDDG--EHKRGDNARPSH-GLQDDAPRPRA 437 P ++ G AP GE G Q RG N P + G + DA P A Sbjct: 658 PGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGA 717 Query: 438 VTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSP 497 G++ + L PGP + + A +G DG PG L P Sbjct: 718 PGSQGAPGLQGMPGERGAAGL-PGP---KGDRGDAGPKG-ADGSPGKDGVRGLTGPIGPP 772 Query: 498 PAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARAGTQGLPLPGTEAEPGAL 557 G+ P G G PGP G PG + EPG Sbjct: 773 GPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDA 832 Query: 558 GCSLSRGP 565 G GP Sbjct: 833 GAKGDAGP 840 Score = 30.8 bits (68), Expect = 5.1 Identities = 72/267 (26%), Positives = 90/267 (33%), Gaps = 48/267 (17%) Query: 330 PGPVVLPGQEVEGKDVSRQTREADGEQNPK-EEAPRGTGGEVGLHHTGKHEAEEAQGPQK 388 PGP PG+ + + + R GE+ P + RG G GL H K Sbjct: 223 PGP---PGKNGDDGEAGKPGRP--GERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAK 277 Query: 389 EEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSH----GLQDDAPRPRAVTQVVVQ 444 + GP KGE G G+N P GL + RP A + Sbjct: 278 GD-AGPAGP-------KGEPGSP-------GENGAPGQMGPRGLPGERGRPGAPGPAGAR 322 Query: 445 GVE-ALAAAGWDMALGP-GP-------------WEQEERQSQAHHQGFVDGHPGSQARLW 489 G + A AAG GP GP Q R S+ QG V G PG Sbjct: 323 GNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGP-QG-VRGEPGPPGPAG 380 Query: 490 LALTWDSPPAPLQRSVWGQL-QPQAGGGRGWEG-RGA----GRWARPGPGWDGGARAGTQ 543 A +P A Q G P G G+ G RG G PGP + G Sbjct: 381 AAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPG 440 Query: 544 GLPLPGTEAEPGALGCSLSRGPVPRQG 570 G + EPG +G GP +G Sbjct: 441 SKGDTGAKGEPGPVGVQGPPGPAGEEG 467 Score = 30.4 bits (67), Expect = 6.6 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 13/78 (16%) Query: 497 PPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA--GTQGLP-------L 547 PP P + G PQ G++ + G + PGP G R G G P Sbjct: 149 PPGP--PGLGGNFAPQLS--YGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGP 204 Query: 548 PGTEAEPGALGCSLSRGP 565 PG EPGA G RGP Sbjct: 205 PGEPGEPGASGPMGPRGP 222 >gi|122937233 discs, large (Drosophila) homolog-associated protein 3 [Homo sapiens] Length = 979 Score = 37.0 bits (84), Expect = 0.071 Identities = 54/229 (23%), Positives = 79/229 (34%), Gaps = 41/229 (17%) Query: 175 AGLGHLGDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAV-------SIHDDPHHPY 227 AGLGH+ G + EGP +G EG + GG+ + D HP Sbjct: 52 AGLGHISPEGP-LSLSEGPSVGPEGGPAGAGVGGGSSTFPRMYPGQGPFDTCEDCVGHPQ 110 Query: 228 GNGGGCGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPA 287 G G P L P L+ + +Q D H + G G GPA Sbjct: 111 GKGA--------PRLPPTLL---------DQFEKQLPVQQDGFHTLPYQRGPAGAGPGPA 153 Query: 288 CAAVALRAALATAPNQGDDQPLCIDDDLYQGQQ---QSHSEDHPAPGPVVLPGQEVEGKD 344 TAP + P I ++ Q+ +SHS + APG G + EG+ Sbjct: 154 -------PGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLE--APGKRDYNGPKAEGRG 204 Query: 345 VSRQTREADGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLG 393 S D P P + HH H++ + + ++ G Sbjct: 205 GS----GGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKG 249 >gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] Length = 1336 Score = 37.0 bits (84), Expect = 0.071 Identities = 73/320 (22%), Positives = 102/320 (31%), Gaps = 57/320 (17%) Query: 251 QGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQGDDQPLC 310 +GGPGP H + GDG G GP A R P +D Sbjct: 1047 RGGPGPPFPPD---------HREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFR 1097 Query: 311 --IDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRGT-- 366 ++ +G H P G PG E G + + E RGT Sbjct: 1098 GRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPR 1157 Query: 367 GGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSH 426 GG GL T E +G +K + + P GH+ + R D+ P H Sbjct: 1158 GGRKGLLPT-PDEFPRFEGGRKPDSWDGNREP--------GPGHEHFRDTPRPDH--PPH 1206 Query: 427 GLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQA------HHQGFVDG 480 A R R+ + +QG++ + GP E R+ +A G G Sbjct: 1207 DGHSPASRERSSS---LQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRG 1263 Query: 481 HPGSQARLWLALTWDSPPAPLQRSVWGQLQ-----------PQAGGGRGWEGRGAGRWAR 529 PG R+ P + S+ G+ P G GR W R Sbjct: 1264 GPGPAQRV--------PKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGR 1315 Query: 530 -----PGPGWDGGARAGTQG 544 GP G +R G +G Sbjct: 1316 GSNMNSGPPRRGASRGGGRG 1335 Score = 30.4 bits (67), Expect = 6.6 Identities = 69/296 (23%), Positives = 98/296 (33%), Gaps = 46/296 (15%) Query: 191 EGPGIGGEGDGQRGVI-PGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDPM--LTPALV 247 +GP + G G +G + P G + D H P G + H P L P Sbjct: 638 QGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM-----QRHPGPHGPLGP--- 689 Query: 248 AATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQGDDQ 307 QG PGPQ + Q H + G G GP + + T QG Sbjct: 690 ---QGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQ-GHLGPQGPPGTQGMQGPPG 745 Query: 308 PLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRGTG 367 P + QG H PG + G +G + R G P+E Sbjct: 746 PRGM-----QGPPHPHG-IQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQ 799 Query: 368 GEV---------GLHHTG---KHEAEEAQGPQKEEYL--GPQQAPFLGVLH--KGEAGHQ 411 G + G H G H +E +GPQ+ + P Q LG +G G Q Sbjct: 800 GMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQ 859 Query: 412 DDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEE 467 +G P G P P+ + A G + GP P++Q++ Sbjct: 860 SQQGPPQGSLGPPPQGGMQGPPGPQG---------QQNPARGPHPSQGPIPFQQQK 906 Score = 30.4 bits (67), Expect = 6.6 Identities = 31/123 (25%), Positives = 46/123 (37%), Gaps = 20/123 (16%) Query: 317 QGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTG 376 QGQQ HP+ GP+ P Q+ + DG + P + + TG + G Sbjct: 884 QGQQNPARGPHPSQGPI--PFQQ------QKTPLLGDGPRAPFNQEGQSTGPPPLIPGLG 935 Query: 377 KHEAE---------EAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHG 427 + A+ + GP K + GP P + E H+ G + G P G Sbjct: 936 QQGAQGRIPPLNPGQGPGPNKGDSRGP---PNHHMGPMSERRHEQSGGPEHGPERGPFRG 992 Query: 428 LQD 430 QD Sbjct: 993 GQD 995 >gi|4502081 amphiphysin isoform 1 [Homo sapiens] Length = 695 Score = 36.6 bits (83), Expect = 0.092 Identities = 29/116 (25%), Positives = 49/116 (42%), Gaps = 8/116 (6%) Query: 326 DHPAPGPVVLPGQEVEGK--DVSRQTREADGEQNPKEEA--PRGTGGEVGLHHTGKHEAE 381 + P V++PG + + + A GE+ E+A P G G + G E Sbjct: 459 EEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTE 518 Query: 382 EAQGPQKE----EYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAP 433 A+ Q E E PQ+ V+ + + H+++GE++ A P +D AP Sbjct: 519 GAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAP 574 >gi|154146231 DMRT-like family A2 [Homo sapiens] Length = 542 Score = 36.6 bits (83), Expect = 0.092 Identities = 82/319 (25%), Positives = 106/319 (33%), Gaps = 92/319 (28%) Query: 279 GTGGGHGPACAAVA------------LRAALATAPNQGDDQPLCIDDDLYQGQQQSHSED 326 GTGGG A + A L+A +P +PL D G S E Sbjct: 175 GTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLS-PDGADSGPGTSSPEV 233 Query: 327 HPAPGPVVLPGQEVEGKDVSRQTREADG-------------EQNPKEEAPRGTGGEVGLH 373 P G G+ G ++R ++EA G E +P +P G+ E G Sbjct: 234 RPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGS--ESG-S 290 Query: 374 HTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAP 433 K E E A P GP+Q L +L + GH+ Sbjct: 291 EADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHR---------------------- 328 Query: 434 RPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALT 493 R V ++V+QG G D+ Q Q HH+G G A L Sbjct: 329 --RGVLELVLQG------CGGDVV-------QAIEQVLNHHRG------GLAAGL----- 362 Query: 494 WDSPPAPLQRSVWGQLQPQAGGGRGWEGR----GAGRWARPGPGWDGGARAGTQGLP--- 546 P AP ++ G A W R A A GPG +AG P Sbjct: 363 --GPAAPPDKAAVG---AAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHR 417 Query: 547 --LPGTEAEPGALGCSLSR 563 L G A PGALG SR Sbjct: 418 PLLAGAMA-PGALGSLSSR 435 Score = 30.8 bits (68), Expect = 5.1 Identities = 39/138 (28%), Positives = 51/138 (36%), Gaps = 14/138 (10%) Query: 182 DLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDPM 241 + G GPG GGE D P G+ A + G GGG G + P Sbjct: 258 EAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTP- 316 Query: 242 LTPALVAATQGGPGPQEGT-----QQQQHDVDECHDKV--HVGDGTGGGHGPACAAVALR 294 L T+ PG + G Q DV + ++V H G G GP AA + Sbjct: 317 ----LDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGP--AAPPDK 370 Query: 295 AALATAPNQGDDQPLCID 312 AA+ A D P +D Sbjct: 371 AAVGAAAAADDAWPSRVD 388 >gi|60097902 filaggrin [Homo sapiens] Length = 4061 Score = 36.2 bits (82), Expect = 0.12 Identities = 56/282 (19%), Positives = 90/282 (31%), Gaps = 65/282 (23%) Query: 178 GHLGDLGDDVEEDEG-------PGIGGEGD-------------GQRGVIPGGTVVLLVAV 217 GH G G + EG + G G G+ G G + L V Sbjct: 413 GHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQV 472 Query: 218 SIHDDPHHPYGNGGGCGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVG 277 S H+ P +G G G ++G+ +Q H G Sbjct: 473 STHEQPDSAHGRTGT--------------------STGGRQGSHHEQARDSSRHSASQEG 512 Query: 278 DGTGGGHGPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPG 337 T GH + + QG ++ + G SH+ G Sbjct: 513 QDTIRGHPGS----------SRGGRQGSHHEQSVNRSGHSGSHHSHTTSQ---GRSDASH 559 Query: 338 QEVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQ--KEEYLGPQ 395 + + SRQTR +E++ GT HH +A+ ++ Q + + GP+ Sbjct: 560 GQSGSRSASRQTRN-------EEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPR 612 Query: 396 QAPFLGVLHKGEA---GHQDDGEHKRGDNARPSHGLQDDAPR 434 + G ++ GH +D E G +R HG + R Sbjct: 613 TSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSR 654 Score = 33.5 bits (75), Expect = 0.78 Identities = 64/300 (21%), Positives = 92/300 (30%), Gaps = 76/300 (25%) Query: 201 GQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDPMLTPALVAATQGGPGPQEGT 260 GQ G G + L VS H+ +G A + GG ++G+ Sbjct: 2078 GQSGESSGRSGSFLYQVSTHEQSESTHGQS-----------------APSTGG---RQGS 2117 Query: 261 QQQQHDVDECHDKVHVGDGTGGGH-GPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQ 319 Q H G T GH GP+ QG Q +D + G Sbjct: 2118 HYDQAQDSSRHSASQEGQDTIRGHPGPSRGG-----------RQGSHQEQSVDRSGHSGS 2166 Query: 320 QQSHSEDHPAPGPVVLPGQEVEGKDVSRQ---TREADGEQNPKEEAPRGTGGEVGLHHTG 376 SH+ D SR +R A + KE++ G+ HH Sbjct: 2167 HHSHTTSQGR-------------SDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEA 2213 Query: 377 KHEAE----------EAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSH 426 A+ ++ GP+ G + GH +D E + G +R H Sbjct: 2214 SSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQ-----DSDSEGHSEDSERRSGSASRNHH 2268 Query: 427 GLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDGHPGSQA 486 G + R G + D A G G + RQS HH + G QA Sbjct: 2269 GSAQEQSR---------DGSRHPRSHHEDRA-GHGHSAESSRQSGTHH---AENSSGGQA 2315 Score = 30.8 bits (68), Expect = 5.1 Identities = 41/193 (21%), Positives = 68/193 (35%), Gaps = 30/193 (15%) Query: 255 GPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQGDDQPLCIDDD 314 G ++G+ +Q H G T GH + ++ QG +D Sbjct: 2436 GGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGS----------SSGGRQGSHYEQLVDRS 2485 Query: 315 LYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHH 374 + G SH+ G + SRQTR E++ G+ HH Sbjct: 2486 GHSGSHHSHTTSQ---GRSDASHGHSGSRSASRQTRN-------DEQSGDGSRHSGSRHH 2535 Query: 375 TGKHEAEEAQGPQ--KEEYLGPQQAPFLGVLHKGEA---GHQDDGEHKRGDNARPSHG-- 427 A+ + Q + + GP+ + G ++ GH +D E G +R HG Sbjct: 2536 EASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSA 2595 Query: 428 ---LQDDAPRPRA 437 L+D + PR+ Sbjct: 2596 QEQLRDGSRHPRS 2608 >gi|239751449 PREDICTED: hypothetical protein XP_002347867 [Homo sapiens] Length = 315 Score = 36.2 bits (82), Expect = 0.12 Identities = 56/209 (26%), Positives = 73/209 (34%), Gaps = 40/209 (19%) Query: 440 QVVVQGVEALAAAGWDMALGPGPWE-QEERQSQAHHQGFVDGHPGSQARLWLALTWDSPP 498 +V G LA G P P+ + ER S+ H G PGS+ R + D P Sbjct: 42 EVAPAGGSPLAVGGAFRVSSPRPFPPRPERPSRRHRAGCGAHGPGSRGRERRRGSRDPPA 101 Query: 499 APLQ------RSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGG-----------ARAG 541 P+ RS G QP +G G A A P P WD + Sbjct: 102 GPVARARARGRSAPGSAQPASGAA----GPAAAPEAAP-PAWDPATLPPSRKRNSLGSSP 156 Query: 542 TQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYIT----SIQGANRAPA 597 + L A G G S+ R V +L A+V W+ HR+ S+Q A P Sbjct: 157 LHPVRLGRVRAHAGPAGTSILR--VAPHPALPGAQVHWAGRHRWAARRGKSLQSAWWGPG 214 Query: 598 ALQVRALRLHRNKACP---ALPAPTHLQA 623 RN P PAP +A Sbjct: 215 G--------RRNSISPGRTTFPAPPTQEA 235 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.136 0.438 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 40,550,072 Number of Sequences: 37866 Number of extensions: 2500425 Number of successful extensions: 10342 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 23 Number of HSP's successfully gapped in prelim test: 290 Number of HSP's that attempted gapping in prelim test: 9414 Number of HSP's gapped (non-prelim): 1176 length of query: 783 length of database: 18,247,518 effective HSP length: 110 effective length of query: 673 effective length of database: 14,082,258 effective search space: 9477359634 effective search space used: 9477359634 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.