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Search of human proteins with 119395734
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|119395734 breast cancer 2, early onset [Homo sapiens]
(3418 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|119395734 breast cancer 2, early onset [Homo sapiens] 6811 0.0
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 51 2e-05
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 51 2e-05
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 47 3e-04
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 47 3e-04
gi|87299628 biorientation of chromosomes in cell division 1-like... 44 0.003
gi|71061468 centromere protein E [Homo sapiens] 44 0.003
gi|31657119 carboxypeptidase 2, cytosolic [Homo sapiens] 42 0.010
gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens] 42 0.014
gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens] 42 0.014
gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens] 42 0.014
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 41 0.023
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 41 0.023
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 40 0.040
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 40 0.052
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 39 0.068
gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens] 39 0.068
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 39 0.068
gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens] 39 0.12
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] 39 0.12
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 38 0.15
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 38 0.15
gi|62821787 COBL-like 1 [Homo sapiens] 38 0.15
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 37 0.26
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 37 0.26
gi|130980075 centromere protein J [Homo sapiens] 37 0.34
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 37 0.34
gi|22749197 motile sperm domain containing 2 [Homo sapiens] 37 0.34
gi|42415492 chromosome 14 open reading frame 106 [Homo sapiens] 37 0.44
gi|133778961 testis expressed 15 [Homo sapiens] 37 0.44
>gi|119395734 breast cancer 2, early onset [Homo sapiens]
Length = 3418
Score = 6811 bits (17670), Expect = 0.0
Identities = 3418/3418 (100%), Positives = 3418/3418 (100%)
Query: 1 MPIGSKERPTFFEIFKTRCNKADLGPISLNWFEELSSEAPPYNSEPAEESEHKNNNYEPN 60
MPIGSKERPTFFEIFKTRCNKADLGPISLNWFEELSSEAPPYNSEPAEESEHKNNNYEPN
Sbjct: 1 MPIGSKERPTFFEIFKTRCNKADLGPISLNWFEELSSEAPPYNSEPAEESEHKNNNYEPN 60
Query: 61 LFKTPQRKPSYNQLASTPIIFKEQGLTLPLYQSPVKELDKFKLDLGRNVPNSRHKSLRTV 120
LFKTPQRKPSYNQLASTPIIFKEQGLTLPLYQSPVKELDKFKLDLGRNVPNSRHKSLRTV
Sbjct: 61 LFKTPQRKPSYNQLASTPIIFKEQGLTLPLYQSPVKELDKFKLDLGRNVPNSRHKSLRTV 120
Query: 121 KTKMDQADDVSCPLLNSCLSESPVVLQCTHVTPQRDKSVVCGSLFHTPKFVKGRQTPKHI 180
KTKMDQADDVSCPLLNSCLSESPVVLQCTHVTPQRDKSVVCGSLFHTPKFVKGRQTPKHI
Sbjct: 121 KTKMDQADDVSCPLLNSCLSESPVVLQCTHVTPQRDKSVVCGSLFHTPKFVKGRQTPKHI 180
Query: 181 SESLGAEVDPDMSWSSSLATPPTLSSTVLIVRNEEASETVFPHDTTANVKSYFSNHDESL 240
SESLGAEVDPDMSWSSSLATPPTLSSTVLIVRNEEASETVFPHDTTANVKSYFSNHDESL
Sbjct: 181 SESLGAEVDPDMSWSSSLATPPTLSSTVLIVRNEEASETVFPHDTTANVKSYFSNHDESL 240
Query: 241 KKNDRFIASVTDSENTNQREAASHGFGKTSGNSFKVNSCKDHIGKSMPNVLEDEVYETVV 300
KKNDRFIASVTDSENTNQREAASHGFGKTSGNSFKVNSCKDHIGKSMPNVLEDEVYETVV
Sbjct: 241 KKNDRFIASVTDSENTNQREAASHGFGKTSGNSFKVNSCKDHIGKSMPNVLEDEVYETVV 300
Query: 301 DTSEEDSFSLCFSKCRTKNLQKVRTSKTRKKIFHEANADECEKSKNQVKEKYSFVSEVEP 360
DTSEEDSFSLCFSKCRTKNLQKVRTSKTRKKIFHEANADECEKSKNQVKEKYSFVSEVEP
Sbjct: 301 DTSEEDSFSLCFSKCRTKNLQKVRTSKTRKKIFHEANADECEKSKNQVKEKYSFVSEVEP 360
Query: 361 NDTDPLDSNVANQKPFESGSDKISKEVVPSLACEWSQLTLSGLNGAQMEKIPLLHISSCD 420
NDTDPLDSNVANQKPFESGSDKISKEVVPSLACEWSQLTLSGLNGAQMEKIPLLHISSCD
Sbjct: 361 NDTDPLDSNVANQKPFESGSDKISKEVVPSLACEWSQLTLSGLNGAQMEKIPLLHISSCD 420
Query: 421 QNISEKDLLDTENKRKKDFLTSENSLPRISSLPKSEKPLNEETVVNKRDEEQHLESHTDC 480
QNISEKDLLDTENKRKKDFLTSENSLPRISSLPKSEKPLNEETVVNKRDEEQHLESHTDC
Sbjct: 421 QNISEKDLLDTENKRKKDFLTSENSLPRISSLPKSEKPLNEETVVNKRDEEQHLESHTDC 480
Query: 481 ILAVKQAISGTSPVASSFQGIKKSIFRIRESPKETFNASFSGHMTDPNFKKETEASESGL 540
ILAVKQAISGTSPVASSFQGIKKSIFRIRESPKETFNASFSGHMTDPNFKKETEASESGL
Sbjct: 481 ILAVKQAISGTSPVASSFQGIKKSIFRIRESPKETFNASFSGHMTDPNFKKETEASESGL 540
Query: 541 EIHTVCSQKEDSLCPNLIDNGSWPATTTQNSVALKNAGLISTLKKKTNKFIYAIHDETSY 600
EIHTVCSQKEDSLCPNLIDNGSWPATTTQNSVALKNAGLISTLKKKTNKFIYAIHDETSY
Sbjct: 541 EIHTVCSQKEDSLCPNLIDNGSWPATTTQNSVALKNAGLISTLKKKTNKFIYAIHDETSY 600
Query: 601 KGKKIPKDQKSELINCSAQFEANAFEAPLTFANADSGLLHSSVKRSCSQNDSEEPTLSLT 660
KGKKIPKDQKSELINCSAQFEANAFEAPLTFANADSGLLHSSVKRSCSQNDSEEPTLSLT
Sbjct: 601 KGKKIPKDQKSELINCSAQFEANAFEAPLTFANADSGLLHSSVKRSCSQNDSEEPTLSLT 660
Query: 661 SSFGTILRKCSRNETCSNNTVISQDLDYKEAKCNKEKLQLFITPEADSLSCLQEGQCEND 720
SSFGTILRKCSRNETCSNNTVISQDLDYKEAKCNKEKLQLFITPEADSLSCLQEGQCEND
Sbjct: 661 SSFGTILRKCSRNETCSNNTVISQDLDYKEAKCNKEKLQLFITPEADSLSCLQEGQCEND 720
Query: 721 PKSKKVSDIKEEVLAAACHPVQHSKVEYSDTDFQSQKSLLYDHENASTLILTPTSKDVLS 780
PKSKKVSDIKEEVLAAACHPVQHSKVEYSDTDFQSQKSLLYDHENASTLILTPTSKDVLS
Sbjct: 721 PKSKKVSDIKEEVLAAACHPVQHSKVEYSDTDFQSQKSLLYDHENASTLILTPTSKDVLS 780
Query: 781 NLVMISRGKESYKMSDKLKGNNYESDVELTKNIPMEKNQDVCALNENYKNVELLPPEKYM 840
NLVMISRGKESYKMSDKLKGNNYESDVELTKNIPMEKNQDVCALNENYKNVELLPPEKYM
Sbjct: 781 NLVMISRGKESYKMSDKLKGNNYESDVELTKNIPMEKNQDVCALNENYKNVELLPPEKYM 840
Query: 841 RVASPSRKVQFNQNTNLRVIQKNQEETTSISKITVNPDSEELFSDNENNFVFQVANERNN 900
RVASPSRKVQFNQNTNLRVIQKNQEETTSISKITVNPDSEELFSDNENNFVFQVANERNN
Sbjct: 841 RVASPSRKVQFNQNTNLRVIQKNQEETTSISKITVNPDSEELFSDNENNFVFQVANERNN 900
Query: 901 LALGNTKELHETDLTCVNEPIFKNSTMVLYGDTGDKQATQVSIKKDLVYVLAEENKNSVK 960
LALGNTKELHETDLTCVNEPIFKNSTMVLYGDTGDKQATQVSIKKDLVYVLAEENKNSVK
Sbjct: 901 LALGNTKELHETDLTCVNEPIFKNSTMVLYGDTGDKQATQVSIKKDLVYVLAEENKNSVK 960
Query: 961 QHIKMTLGQDLKSDISLNIDKIPEKNNDYMNKWAGLLGPISNHSFGGSFRTASNKEIKLS 1020
QHIKMTLGQDLKSDISLNIDKIPEKNNDYMNKWAGLLGPISNHSFGGSFRTASNKEIKLS
Sbjct: 961 QHIKMTLGQDLKSDISLNIDKIPEKNNDYMNKWAGLLGPISNHSFGGSFRTASNKEIKLS 1020
Query: 1021 EHNIKKSKMFFKDIEEQYPTSLACVEIVNTLALDNQKKLSKPQSINTVSAHLQSSVVVSD 1080
EHNIKKSKMFFKDIEEQYPTSLACVEIVNTLALDNQKKLSKPQSINTVSAHLQSSVVVSD
Sbjct: 1021 EHNIKKSKMFFKDIEEQYPTSLACVEIVNTLALDNQKKLSKPQSINTVSAHLQSSVVVSD 1080
Query: 1081 CKNSHITPQMLFSKQDFNSNHNLTPSQKAEITELSTILEESGSQFEFTQFRKPSYILQKS 1140
CKNSHITPQMLFSKQDFNSNHNLTPSQKAEITELSTILEESGSQFEFTQFRKPSYILQKS
Sbjct: 1081 CKNSHITPQMLFSKQDFNSNHNLTPSQKAEITELSTILEESGSQFEFTQFRKPSYILQKS 1140
Query: 1141 TFEVPENQMTILKTTSEECRDADLHVIMNAPSIGQVDSSKQFEGTVEIKRKFAGLLKNDC 1200
TFEVPENQMTILKTTSEECRDADLHVIMNAPSIGQVDSSKQFEGTVEIKRKFAGLLKNDC
Sbjct: 1141 TFEVPENQMTILKTTSEECRDADLHVIMNAPSIGQVDSSKQFEGTVEIKRKFAGLLKNDC 1200
Query: 1201 NKSASGYLTDENEVGFRGFYSAHGTKLNVSTEALQKAVKLFSDIENISEETSAEVHPISL 1260
NKSASGYLTDENEVGFRGFYSAHGTKLNVSTEALQKAVKLFSDIENISEETSAEVHPISL
Sbjct: 1201 NKSASGYLTDENEVGFRGFYSAHGTKLNVSTEALQKAVKLFSDIENISEETSAEVHPISL 1260
Query: 1261 SSSKCHDSVVSMFKIENHNDKTVSEKNNKCQLILQNNIEMTTGTFVEEITENYKRNTENE 1320
SSSKCHDSVVSMFKIENHNDKTVSEKNNKCQLILQNNIEMTTGTFVEEITENYKRNTENE
Sbjct: 1261 SSSKCHDSVVSMFKIENHNDKTVSEKNNKCQLILQNNIEMTTGTFVEEITENYKRNTENE 1320
Query: 1321 DNKYTAASRNSHNLEFDGSDSSKNDTVCIHKDETDLLFTDQHNICLKLSGQFMKEGNTQI 1380
DNKYTAASRNSHNLEFDGSDSSKNDTVCIHKDETDLLFTDQHNICLKLSGQFMKEGNTQI
Sbjct: 1321 DNKYTAASRNSHNLEFDGSDSSKNDTVCIHKDETDLLFTDQHNICLKLSGQFMKEGNTQI 1380
Query: 1381 KEDLSDLTFLEVAKAQEACHGNTSNKEQLTATKTEQNIKDFETSDTFFQTASGKNISVAK 1440
KEDLSDLTFLEVAKAQEACHGNTSNKEQLTATKTEQNIKDFETSDTFFQTASGKNISVAK
Sbjct: 1381 KEDLSDLTFLEVAKAQEACHGNTSNKEQLTATKTEQNIKDFETSDTFFQTASGKNISVAK 1440
Query: 1441 ESFNKIVNFFDQKPEELHNFSLNSELHSDIRKNKMDILSYEETDIVKHKILKESVPVGTG 1500
ESFNKIVNFFDQKPEELHNFSLNSELHSDIRKNKMDILSYEETDIVKHKILKESVPVGTG
Sbjct: 1441 ESFNKIVNFFDQKPEELHNFSLNSELHSDIRKNKMDILSYEETDIVKHKILKESVPVGTG 1500
Query: 1501 NQLVTFQGQPERDEKIKEPTLLGFHTASGKKVKIAKESLDKVKNLFDEKEQGTSEITSFS 1560
NQLVTFQGQPERDEKIKEPTLLGFHTASGKKVKIAKESLDKVKNLFDEKEQGTSEITSFS
Sbjct: 1501 NQLVTFQGQPERDEKIKEPTLLGFHTASGKKVKIAKESLDKVKNLFDEKEQGTSEITSFS 1560
Query: 1561 HQWAKTLKYREACKDLELACETIEITAAPKCKEMQNSLNNDKNLVSIETVVPPKLLSDNL 1620
HQWAKTLKYREACKDLELACETIEITAAPKCKEMQNSLNNDKNLVSIETVVPPKLLSDNL
Sbjct: 1561 HQWAKTLKYREACKDLELACETIEITAAPKCKEMQNSLNNDKNLVSIETVVPPKLLSDNL 1620
Query: 1621 CRQTENLKTSKSIFLKVKVHENVEKETAKSPATCYTNQSPYSVIENSALAFYTSCSRKTS 1680
CRQTENLKTSKSIFLKVKVHENVEKETAKSPATCYTNQSPYSVIENSALAFYTSCSRKTS
Sbjct: 1621 CRQTENLKTSKSIFLKVKVHENVEKETAKSPATCYTNQSPYSVIENSALAFYTSCSRKTS 1680
Query: 1681 VSQTSLLEAKKWLREGIFDGQPERINTADYVGNYLYENNSNSTIAENDKNHLSEKQDTYL 1740
VSQTSLLEAKKWLREGIFDGQPERINTADYVGNYLYENNSNSTIAENDKNHLSEKQDTYL
Sbjct: 1681 VSQTSLLEAKKWLREGIFDGQPERINTADYVGNYLYENNSNSTIAENDKNHLSEKQDTYL 1740
Query: 1741 SNSSMSNSYSYHSDEVYNDSGYLSKNKLDSGIEPVLKNVEDQKNTSFSKVISNVKDANAY 1800
SNSSMSNSYSYHSDEVYNDSGYLSKNKLDSGIEPVLKNVEDQKNTSFSKVISNVKDANAY
Sbjct: 1741 SNSSMSNSYSYHSDEVYNDSGYLSKNKLDSGIEPVLKNVEDQKNTSFSKVISNVKDANAY 1800
Query: 1801 PQTVNEDICVEELVTSSSPCKNKNAAIKLSISNSNNFEVGPPAFRIASGKIVCVSHETIK 1860
PQTVNEDICVEELVTSSSPCKNKNAAIKLSISNSNNFEVGPPAFRIASGKIVCVSHETIK
Sbjct: 1801 PQTVNEDICVEELVTSSSPCKNKNAAIKLSISNSNNFEVGPPAFRIASGKIVCVSHETIK 1860
Query: 1861 KVKDIFTDSFSKVIKENNENKSKICQTKIMAGCYEALDDSEDILHNSLDNDECSTHSHKV 1920
KVKDIFTDSFSKVIKENNENKSKICQTKIMAGCYEALDDSEDILHNSLDNDECSTHSHKV
Sbjct: 1861 KVKDIFTDSFSKVIKENNENKSKICQTKIMAGCYEALDDSEDILHNSLDNDECSTHSHKV 1920
Query: 1921 FADIQSEEILQHNQNMSGLEKVSKISPCDVSLETSDICKCSIGKLHKSVSSANTCGIFST 1980
FADIQSEEILQHNQNMSGLEKVSKISPCDVSLETSDICKCSIGKLHKSVSSANTCGIFST
Sbjct: 1921 FADIQSEEILQHNQNMSGLEKVSKISPCDVSLETSDICKCSIGKLHKSVSSANTCGIFST 1980
Query: 1981 ASGKSVQVSDASLQNARQVFSEIEDSTKQVFSKVLFKSNEHSDQLTREENTAIRTPEHLI 2040
ASGKSVQVSDASLQNARQVFSEIEDSTKQVFSKVLFKSNEHSDQLTREENTAIRTPEHLI
Sbjct: 1981 ASGKSVQVSDASLQNARQVFSEIEDSTKQVFSKVLFKSNEHSDQLTREENTAIRTPEHLI 2040
Query: 2041 SQKGFSYNVVNSSAFSGFSTASGKQVSILESSLHKVKGVLEEFDLIRTEHSLHYSPTSRQ 2100
SQKGFSYNVVNSSAFSGFSTASGKQVSILESSLHKVKGVLEEFDLIRTEHSLHYSPTSRQ
Sbjct: 2041 SQKGFSYNVVNSSAFSGFSTASGKQVSILESSLHKVKGVLEEFDLIRTEHSLHYSPTSRQ 2100
Query: 2101 NVSKILPRVDKRNPEHCVNSEMEKTCSKEFKLSNNLNVEGGSSENNHSIKVSPYLSQFQQ 2160
NVSKILPRVDKRNPEHCVNSEMEKTCSKEFKLSNNLNVEGGSSENNHSIKVSPYLSQFQQ
Sbjct: 2101 NVSKILPRVDKRNPEHCVNSEMEKTCSKEFKLSNNLNVEGGSSENNHSIKVSPYLSQFQQ 2160
Query: 2161 DKQQLVLGTKVSLVENIHVLGKEQASPKNVKMEIGKTETFSDVPVKTNIEVCSTYSKDSE 2220
DKQQLVLGTKVSLVENIHVLGKEQASPKNVKMEIGKTETFSDVPVKTNIEVCSTYSKDSE
Sbjct: 2161 DKQQLVLGTKVSLVENIHVLGKEQASPKNVKMEIGKTETFSDVPVKTNIEVCSTYSKDSE 2220
Query: 2221 NYFETEAVEIAKAFMEDDELTDSKLPSHATHSLFTCPENEEMVLSNSRIGKRRGEPLILV 2280
NYFETEAVEIAKAFMEDDELTDSKLPSHATHSLFTCPENEEMVLSNSRIGKRRGEPLILV
Sbjct: 2221 NYFETEAVEIAKAFMEDDELTDSKLPSHATHSLFTCPENEEMVLSNSRIGKRRGEPLILV 2280
Query: 2281 GEPSIKRNLLNEFDRIIENQEKSLKASKSTPDGTIKDRRLFMHHVSLEPITCVPFRTTKE 2340
GEPSIKRNLLNEFDRIIENQEKSLKASKSTPDGTIKDRRLFMHHVSLEPITCVPFRTTKE
Sbjct: 2281 GEPSIKRNLLNEFDRIIENQEKSLKASKSTPDGTIKDRRLFMHHVSLEPITCVPFRTTKE 2340
Query: 2341 RQEIQNPNFTAPGQEFLSKSHLYEHLTLEKSSSNLAVSGHPFYQVSATRNEKMRHLITTG 2400
RQEIQNPNFTAPGQEFLSKSHLYEHLTLEKSSSNLAVSGHPFYQVSATRNEKMRHLITTG
Sbjct: 2341 RQEIQNPNFTAPGQEFLSKSHLYEHLTLEKSSSNLAVSGHPFYQVSATRNEKMRHLITTG 2400
Query: 2401 RPTKVFVPPFKTKSHFHRVEQCVRNINLEENRQKQNIDGHGSDDSKNKINDNEIHQFNKN 2460
RPTKVFVPPFKTKSHFHRVEQCVRNINLEENRQKQNIDGHGSDDSKNKINDNEIHQFNKN
Sbjct: 2401 RPTKVFVPPFKTKSHFHRVEQCVRNINLEENRQKQNIDGHGSDDSKNKINDNEIHQFNKN 2460
Query: 2461 NSNQAAAVTFTKCEEEPLDLITSLQNARDIQDMRIKKKQRQRVFPQPGSLYLAKTSTLPR 2520
NSNQAAAVTFTKCEEEPLDLITSLQNARDIQDMRIKKKQRQRVFPQPGSLYLAKTSTLPR
Sbjct: 2461 NSNQAAAVTFTKCEEEPLDLITSLQNARDIQDMRIKKKQRQRVFPQPGSLYLAKTSTLPR 2520
Query: 2521 ISLKAAVGGQVPSACSHKQLYTYGVSKHCIKINSKNAESFQFHTEDYFGKESLWTGKGIQ 2580
ISLKAAVGGQVPSACSHKQLYTYGVSKHCIKINSKNAESFQFHTEDYFGKESLWTGKGIQ
Sbjct: 2521 ISLKAAVGGQVPSACSHKQLYTYGVSKHCIKINSKNAESFQFHTEDYFGKESLWTGKGIQ 2580
Query: 2581 LADGGWLIPSNDGKAGKEEFYRALCDTPGVDPKLISRIWVYNHYRWIIWKLAAMECAFPK 2640
LADGGWLIPSNDGKAGKEEFYRALCDTPGVDPKLISRIWVYNHYRWIIWKLAAMECAFPK
Sbjct: 2581 LADGGWLIPSNDGKAGKEEFYRALCDTPGVDPKLISRIWVYNHYRWIIWKLAAMECAFPK 2640
Query: 2641 EFANRCLSPERVLLQLKYRYDTEIDRSRRSAIKKIMERDDTAAKTLVLCVSDIISLSANI 2700
EFANRCLSPERVLLQLKYRYDTEIDRSRRSAIKKIMERDDTAAKTLVLCVSDIISLSANI
Sbjct: 2641 EFANRCLSPERVLLQLKYRYDTEIDRSRRSAIKKIMERDDTAAKTLVLCVSDIISLSANI 2700
Query: 2701 SETSSNKTSSADTQKVAIIELTDGWYAVKAQLDPPLLAVLKNGRLTVGQKIILHGAELVG 2760
SETSSNKTSSADTQKVAIIELTDGWYAVKAQLDPPLLAVLKNGRLTVGQKIILHGAELVG
Sbjct: 2701 SETSSNKTSSADTQKVAIIELTDGWYAVKAQLDPPLLAVLKNGRLTVGQKIILHGAELVG 2760
Query: 2761 SPDACTPLEAPESLMLKISANSTRPARWYTKLGFFPDPRPFPLPLSSLFSDGGNVGCVDV 2820
SPDACTPLEAPESLMLKISANSTRPARWYTKLGFFPDPRPFPLPLSSLFSDGGNVGCVDV
Sbjct: 2761 SPDACTPLEAPESLMLKISANSTRPARWYTKLGFFPDPRPFPLPLSSLFSDGGNVGCVDV 2820
Query: 2821 IIQRAYPIQWMEKTSSGLYIFRNEREEEKEAAKYVEAQQKRLEALFTKIQEEFEEHEENT 2880
IIQRAYPIQWMEKTSSGLYIFRNEREEEKEAAKYVEAQQKRLEALFTKIQEEFEEHEENT
Sbjct: 2821 IIQRAYPIQWMEKTSSGLYIFRNEREEEKEAAKYVEAQQKRLEALFTKIQEEFEEHEENT 2880
Query: 2881 TKPYLPSRALTRQQVRALQDGAELYEAVKNAADPAYLEGYFSEEQLRALNNHRQMLNDKK 2940
TKPYLPSRALTRQQVRALQDGAELYEAVKNAADPAYLEGYFSEEQLRALNNHRQMLNDKK
Sbjct: 2881 TKPYLPSRALTRQQVRALQDGAELYEAVKNAADPAYLEGYFSEEQLRALNNHRQMLNDKK 2940
Query: 2941 QAQIQLEIRKAMESAEQKEQGLSRDVTTVWKLRIVSYSKKEKDSVILSIWRPSSDLYSLL 3000
QAQIQLEIRKAMESAEQKEQGLSRDVTTVWKLRIVSYSKKEKDSVILSIWRPSSDLYSLL
Sbjct: 2941 QAQIQLEIRKAMESAEQKEQGLSRDVTTVWKLRIVSYSKKEKDSVILSIWRPSSDLYSLL 3000
Query: 3001 TEGKRYRIYHLATSKSKSKSERANIQLAATKKTQYQQLPVSDEILFQIYQPREPLHFSKF 3060
TEGKRYRIYHLATSKSKSKSERANIQLAATKKTQYQQLPVSDEILFQIYQPREPLHFSKF
Sbjct: 3001 TEGKRYRIYHLATSKSKSKSERANIQLAATKKTQYQQLPVSDEILFQIYQPREPLHFSKF 3060
Query: 3061 LDPDFQPSCSEVDLIGFVVSVVKKTGLAPFVYLSDECYNLLAIKFWIDLNEDIIKPHMLI 3120
LDPDFQPSCSEVDLIGFVVSVVKKTGLAPFVYLSDECYNLLAIKFWIDLNEDIIKPHMLI
Sbjct: 3061 LDPDFQPSCSEVDLIGFVVSVVKKTGLAPFVYLSDECYNLLAIKFWIDLNEDIIKPHMLI 3120
Query: 3121 AASNLQWRPESKSGLLTLFAGDFSVFSASPKEGHFQETFNKMKNTVENIDILCNEAENKL 3180
AASNLQWRPESKSGLLTLFAGDFSVFSASPKEGHFQETFNKMKNTVENIDILCNEAENKL
Sbjct: 3121 AASNLQWRPESKSGLLTLFAGDFSVFSASPKEGHFQETFNKMKNTVENIDILCNEAENKL 3180
Query: 3181 MHILHANDPKWSTPTKDCTSGPYTAQIIPGTGNKLLMSSPNCEIYYQSPLSLCMAKRKSV 3240
MHILHANDPKWSTPTKDCTSGPYTAQIIPGTGNKLLMSSPNCEIYYQSPLSLCMAKRKSV
Sbjct: 3181 MHILHANDPKWSTPTKDCTSGPYTAQIIPGTGNKLLMSSPNCEIYYQSPLSLCMAKRKSV 3240
Query: 3241 STPVSAQMTSKSCKGEKEIDDQKNCKKRRALDFLSRLPLPPPVSPICTFVSPAAQKAFQP 3300
STPVSAQMTSKSCKGEKEIDDQKNCKKRRALDFLSRLPLPPPVSPICTFVSPAAQKAFQP
Sbjct: 3241 STPVSAQMTSKSCKGEKEIDDQKNCKKRRALDFLSRLPLPPPVSPICTFVSPAAQKAFQP 3300
Query: 3301 PRSCGTKYETPIKKKELNSPQMTPFKKFNEISLLESNSIADEELALINTQALLSGSTGEK 3360
PRSCGTKYETPIKKKELNSPQMTPFKKFNEISLLESNSIADEELALINTQALLSGSTGEK
Sbjct: 3301 PRSCGTKYETPIKKKELNSPQMTPFKKFNEISLLESNSIADEELALINTQALLSGSTGEK 3360
Query: 3361 QFISVSESTRTAPTSSEDYLRLKRRCTTSLIKEQESSQASTEECEKNKQDTITTKKYI 3418
QFISVSESTRTAPTSSEDYLRLKRRCTTSLIKEQESSQASTEECEKNKQDTITTKKYI
Sbjct: 3361 QFISVSESTRTAPTSSEDYLRLKRRCTTSLIKEQESSQASTEECEKNKQDTITTKKYI 3418
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 51.2 bits (121), Expect = 2e-05
Identities = 143/731 (19%), Positives = 265/731 (36%), Gaps = 108/731 (14%)
Query: 1855 SHETIKKVKDIFTDSFSKVIKENNENKSKICQTKIMAGC----------YEALDDSEDIL 1904
S+ ++ + + S + I E S IC++K + YE DD ++ +
Sbjct: 289 SYTDSEEAQSVNPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKDDDDEEI 348
Query: 1905 HNSLDN---------DECSTHSHKVFADIQSEEILQHNQNMSGLEKVSKISPCDVSLETS 1955
+ +D+ E + K + E+ S +K S++ S E+S
Sbjct: 349 NKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYS--STESS 406
Query: 1956 DICKCSIGKLHKSVSSANTCGIFSTASGKSVQVSDASLQNARQVFSEIEDSTKQVFSKVL 2015
D K+ S S + K VS Q + V ++++ K ++ L
Sbjct: 407 DEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGK-VKRKLKNQNKNKENQEL 465
Query: 2016 FKSNEHSDQLTREENTAIRT----PEHLISQKGF--SYNVVNSSAFSGFSTASGKQVSIL 2069
K + + TR N + T E + F S++ + ++ F ++GK
Sbjct: 466 -KQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFHISTGK----- 519
Query: 2070 ESSLHKVKGVLEEFDLIRTEHSLH-YSP-TSRQNVSKILPRVDKRNPEHCVNSEMEKTCS 2127
S H ++ ++ EH+ SP +S ++ L R D E S K+C
Sbjct: 520 -SPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCK 578
Query: 2128 --KEFKLSNNLNVEGGSSENNHSIKVSPYLSQFQQDKQQLVLGTKVSLVENIHVLGKEQA 2185
++ K + ++E G ++N IK + F+ L K H L ++
Sbjct: 579 HKEKSKHQKDFHLEFGE-KSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKER 637
Query: 2186 SPKNVKMEI-GKTETFSDVPVKTNIEVCSTYSKD--SENYFETEAVEIAKAFMEDDELTD 2242
+ K EI G+ E + ++ + ++ EN+F+++ E ME + LT
Sbjct: 638 EKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTL 697
Query: 2243 SKLPSHATHSLFTCPENEEMVLSNSRIGKRRGEPLILVGEPSIK----RNLLNEFDRI-- 2296
K S ++ +E +S R K + + E S + ++L E + I
Sbjct: 698 EK-KSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPT 756
Query: 2297 ----------------------------IENQEKSLKASKSTPDGTIKDRRLFMHHVSLE 2328
IE QEK +K SK P+ +R + +E
Sbjct: 757 DKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPE-----KRSQIKEKDIE 811
Query: 2329 PITCVPFRTTKE-----RQEIQNPNFTAPGQEFLSKSHLYEHLTL------EKSSSNLAV 2377
+ F K+ + E + + + K LY H T EKS + A+
Sbjct: 812 KMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAI 871
Query: 2378 SGHPFYQVSATRNEKMRHLITTGRPTKVFVPPFKTKSHFHRVEQCVRNINLEENRQKQNI 2437
+ S EKM +P K H E +++ ++N+Q N
Sbjct: 872 KKTDDREKS---REKMDRKHDKEKPEK----------ERHLAESKEKHLMEKKNKQSDNS 918
Query: 2438 DGHGSDDSKNKINDNEIHQFNKNNSNQAAAVTFTK-CEEEPLDLITSLQNARDIQDMRIK 2496
+ S+ KNK D E+ + K+ ++ +T +K +EE I A+ + + +K
Sbjct: 919 EYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLK 978
Query: 2497 KKQRQRVFPQP 2507
+K + P
Sbjct: 979 EKTKDEPLKTP 989
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 51.2 bits (121), Expect = 2e-05
Identities = 143/731 (19%), Positives = 265/731 (36%), Gaps = 108/731 (14%)
Query: 1855 SHETIKKVKDIFTDSFSKVIKENNENKSKICQTKIMAGC----------YEALDDSEDIL 1904
S+ ++ + + S + I E S IC++K + YE DD ++ +
Sbjct: 312 SYTDSEEAQSVNPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKDDDDEEI 371
Query: 1905 HNSLDN---------DECSTHSHKVFADIQSEEILQHNQNMSGLEKVSKISPCDVSLETS 1955
+ +D+ E + K + E+ S +K S++ S E+S
Sbjct: 372 NKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYS--STESS 429
Query: 1956 DICKCSIGKLHKSVSSANTCGIFSTASGKSVQVSDASLQNARQVFSEIEDSTKQVFSKVL 2015
D K+ S S + K VS Q + V ++++ K ++ L
Sbjct: 430 DEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGK-VKRKLKNQNKNKENQEL 488
Query: 2016 FKSNEHSDQLTREENTAIRT----PEHLISQKGF--SYNVVNSSAFSGFSTASGKQVSIL 2069
K + + TR N + T E + F S++ + ++ F ++GK
Sbjct: 489 -KQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFHISTGK----- 542
Query: 2070 ESSLHKVKGVLEEFDLIRTEHSLH-YSP-TSRQNVSKILPRVDKRNPEHCVNSEMEKTCS 2127
S H ++ ++ EH+ SP +S ++ L R D E S K+C
Sbjct: 543 -SPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCK 601
Query: 2128 --KEFKLSNNLNVEGGSSENNHSIKVSPYLSQFQQDKQQLVLGTKVSLVENIHVLGKEQA 2185
++ K + ++E G ++N IK + F+ L K H L ++
Sbjct: 602 HKEKSKHQKDFHLEFGE-KSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKER 660
Query: 2186 SPKNVKMEI-GKTETFSDVPVKTNIEVCSTYSKD--SENYFETEAVEIAKAFMEDDELTD 2242
+ K EI G+ E + ++ + ++ EN+F+++ E ME + LT
Sbjct: 661 EKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTL 720
Query: 2243 SKLPSHATHSLFTCPENEEMVLSNSRIGKRRGEPLILVGEPSIK----RNLLNEFDRI-- 2296
K S ++ +E +S R K + + E S + ++L E + I
Sbjct: 721 EK-KSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPT 779
Query: 2297 ----------------------------IENQEKSLKASKSTPDGTIKDRRLFMHHVSLE 2328
IE QEK +K SK P+ +R + +E
Sbjct: 780 DKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPE-----KRSQIKEKDIE 834
Query: 2329 PITCVPFRTTKE-----RQEIQNPNFTAPGQEFLSKSHLYEHLTL------EKSSSNLAV 2377
+ F K+ + E + + + K LY H T EKS + A+
Sbjct: 835 KMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAI 894
Query: 2378 SGHPFYQVSATRNEKMRHLITTGRPTKVFVPPFKTKSHFHRVEQCVRNINLEENRQKQNI 2437
+ S EKM +P K H E +++ ++N+Q N
Sbjct: 895 KKTDDREKS---REKMDRKHDKEKPEK----------ERHLAESKEKHLMEKKNKQSDNS 941
Query: 2438 DGHGSDDSKNKINDNEIHQFNKNNSNQAAAVTFTK-CEEEPLDLITSLQNARDIQDMRIK 2496
+ S+ KNK D E+ + K+ ++ +T +K +EE I A+ + + +K
Sbjct: 942 EYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLK 1001
Query: 2497 KKQRQRVFPQP 2507
+K + P
Sbjct: 1002 EKTKDEPLKTP 1012
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 47.0 bits (110), Expect = 3e-04
Identities = 104/551 (18%), Positives = 206/551 (37%), Gaps = 85/551 (15%)
Query: 1795 KDANAYPQTVNEDICVEELVTSSSPCKNKNAAIKLSISNSNNFEVGPPAFRIASGKIVCV 1854
+D++ QT+ ED+C C N+ ++ N E K+ C
Sbjct: 806 QDSHFSIQTIKEDLCHFRTFVQKEQCDFSNSLKCTAVEIRNIIE-----------KVKCS 854
Query: 1855 SHETIKK--------VKDIFTDSFSKVIKENNENKSKICQTKIMAGCYEALDDSEDILHN 1906
T+K+ +K+ + +IKE EN++KI + K C E++L N
Sbjct: 855 LEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCL------EEVLQN 908
Query: 1907 SLDNDECSTHSHKVFADIQSEEILQHNQNMSGLEKVSKISPCDVS--LETSDICKCSIGK 1964
+ H + +Q+E+ +Q + +E + C++ ++ +I + K
Sbjct: 909 KDNEFALVKHEKEAVICLQNEK----DQKLLEMENIMHSQNCEIKELKQSREIVLEDLKK 964
Query: 1965 LHKSVSSANTCGIFSTASGKSVQVSDASLQNARQV-FSEIEDSTK----QVFSKVLFKSN 2019
LH + + +Q+ A LQ+ Q E+ED+ + Q F KV+
Sbjct: 965 LH-------------VENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHR 1011
Query: 2020 EHSDQLTREENTAIRTPEHLIS------QKGFSYNVVNSSAFSGFSTASGKQVSILESSL 2073
++L +E I + + +K + S S ++++ E+
Sbjct: 1012 VSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAET 1071
Query: 2074 HKVKGVLEEFDLIRTE--HSLHYSPTS--RQNVSKILPRVDKRNPEHCVNSEMEKT---- 2125
++K +LEE + E SL T R +SK+ ++ N + V +T
Sbjct: 1072 DEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTI 1131
Query: 2126 ----CSKEFKLSNNLNVEGGSSENNHSIKVSPYLSQFQQDKQQLVLGTKVSLVENIHVLG 2181
C E + +E N + + +++ ++ ++ + L + L
Sbjct: 1132 EKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSAL- 1190
Query: 2182 KEQASPKNVKMEIGKTETFSDVPVKTNIEVCSTYSKDSE------NYFETEAVEIA-KAF 2234
E+ + + + K E K ++ S+ +D E N + EA++ A K F
Sbjct: 1191 -ERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEF 1249
Query: 2235 MEDDELTDSKLPSHATHSLFTCPENEEMVLSNSRIGKRRGEPLILVGEPSIKRNLLNEFD 2294
+ E+ + +L H E + + I RG+ LV E ++ L E
Sbjct: 1250 KLEREVVEKELLEKVKHL-------ENQIAKSPAIDSTRGDSSSLVAE--LQEKLQEEKA 1300
Query: 2295 RIIENQEKSLK 2305
+ +E E+ K
Sbjct: 1301 KFLEQLEEQEK 1311
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 47.0 bits (110), Expect = 3e-04
Identities = 104/551 (18%), Positives = 206/551 (37%), Gaps = 85/551 (15%)
Query: 1795 KDANAYPQTVNEDICVEELVTSSSPCKNKNAAIKLSISNSNNFEVGPPAFRIASGKIVCV 1854
+D++ QT+ ED+C C N+ ++ N E K+ C
Sbjct: 806 QDSHFSIQTIKEDLCHFRTFVQKEQCDFSNSLKCTAVEIRNIIE-----------KVKCS 854
Query: 1855 SHETIKK--------VKDIFTDSFSKVIKENNENKSKICQTKIMAGCYEALDDSEDILHN 1906
T+K+ +K+ + +IKE EN++KI + K C E++L N
Sbjct: 855 LEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCL------EEVLQN 908
Query: 1907 SLDNDECSTHSHKVFADIQSEEILQHNQNMSGLEKVSKISPCDVS--LETSDICKCSIGK 1964
+ H + +Q+E+ +Q + +E + C++ ++ +I + K
Sbjct: 909 KDNEFALVKHEKEAVICLQNEK----DQKLLEMENIMHSQNCEIKELKQSREIVLEDLKK 964
Query: 1965 LHKSVSSANTCGIFSTASGKSVQVSDASLQNARQV-FSEIEDSTK----QVFSKVLFKSN 2019
LH + + +Q+ A LQ+ Q E+ED+ + Q F KV+
Sbjct: 965 LH-------------VENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHR 1011
Query: 2020 EHSDQLTREENTAIRTPEHLIS------QKGFSYNVVNSSAFSGFSTASGKQVSILESSL 2073
++L +E I + + +K + S S ++++ E+
Sbjct: 1012 VSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAET 1071
Query: 2074 HKVKGVLEEFDLIRTE--HSLHYSPTS--RQNVSKILPRVDKRNPEHCVNSEMEKT---- 2125
++K +LEE + E SL T R +SK+ ++ N + V +T
Sbjct: 1072 DEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTI 1131
Query: 2126 ----CSKEFKLSNNLNVEGGSSENNHSIKVSPYLSQFQQDKQQLVLGTKVSLVENIHVLG 2181
C E + +E N + + +++ ++ ++ + L + L
Sbjct: 1132 EKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSAL- 1190
Query: 2182 KEQASPKNVKMEIGKTETFSDVPVKTNIEVCSTYSKDSE------NYFETEAVEIA-KAF 2234
E+ + + + K E K ++ S+ +D E N + EA++ A K F
Sbjct: 1191 -ERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEF 1249
Query: 2235 MEDDELTDSKLPSHATHSLFTCPENEEMVLSNSRIGKRRGEPLILVGEPSIKRNLLNEFD 2294
+ E+ + +L H E + + I RG+ LV E ++ L E
Sbjct: 1250 KLEREVVEKELLEKVKHL-------ENQIAKSPAIDSTRGDSSSLVAE--LQEKLQEEKA 1300
Query: 2295 RIIENQEKSLK 2305
+ +E E+ K
Sbjct: 1301 KFLEQLEEQEK 1311
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 43.9 bits (102), Expect = 0.003
Identities = 176/924 (19%), Positives = 340/924 (36%), Gaps = 144/924 (15%)
Query: 583 LKKKTNKFIYAIHDETSYKGKKIPKDQKSELI-----------NCSAQFEANAFEAPLTF 631
++K ++F+ ++ + G P D+K + + + +A + +T
Sbjct: 151 VEKAVHEFLATLNHKEEGSGNTAPDDEKPDTSLITQGVPTPGPSANVANDAMSILETITS 210
Query: 632 ANADSGLLHSSVKRSCSQNDSEEPTLSLTSSFGTILRKCSRNETCSNNTVISQDLDYKEA 691
N ++ +S + S ++ SE + L S T +T ++ S+D+ KE
Sbjct: 211 LNQEASAARASTETSNAKT-SERASKKLPSQPTT--------DTSTDKERTSEDMADKEK 261
Query: 692 KCNKEKLQLFITPEADSLSCLQEGQCENDPKSKKVSDIKEEVLAAACHPVQHSKVEYSDT 751
ADS EG E PKS++ SD+ V + +H+ + +
Sbjct: 262 ST------------ADSGG---EG-LETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNK 305
Query: 752 DFQSQKSLLYDHENASTLILTPTSKDVLSNLVMISRGKESYKMSDKLKGNNYESDVELTK 811
D Q + S + +N ST K SN + ++ K K + D + K
Sbjct: 306 DVQQESS---EQKNKST---DKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVK 359
Query: 812 NIPMEKNQDVCALNENYKNVELLPPEKYMRVAS--PSRKVQF----NQNTNLRVIQKNQE 865
+ K ++V +L LP EK A K F + L I +
Sbjct: 360 DEKQAKEKEVESLK--------LPSEKNSNKAKTVEGTKEDFSLIDSDVDGLTDITVSSV 411
Query: 866 ETTSISKITVNPDSEELFSDN-----------ENNFVFQVANERNNLALGNTKELHETDL 914
T+ +S + + E + SD+ E N + + ++ + G TK +
Sbjct: 412 HTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRH--- 468
Query: 915 TCVNEPIFKNSTMVLYGDTGDK---QATQVSIKKDLV------YVLAEENKNSVKQHIKM 965
V++P + Y D+ D+ + + SI K+ + E+ + KQ +
Sbjct: 469 AYVHKPYLYSK---YYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEK 525
Query: 966 TLGQDLKSDISLNIDKIPEKNNDYMNKWAGLLGPISNHSFGGSFRTASNKEIKLS----E 1021
T K ++D + E + + A + + + A +K+ K E
Sbjct: 526 TKSSKTKGQGRSSVD-LEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVE 584
Query: 1022 HNIKKSKMFFKDIEEQYPTSLACVEIVNTLALDNQKKLSKPQSINTVSAHLQSSVVVSDC 1081
N KK + + +D +E TS C ++K+S + + V A + S
Sbjct: 585 ENSKKKQQYEEDSKETLKTSEHC----------EKEKISSSKELKHVHAKSEPSKPARRL 634
Query: 1082 KNS-HITPQMLFSKQDFNSNHNLTPSQKAEITELSTILEESGSQFEFTQFRKPSYILQKS 1140
S H+ D N N + + T I+E G Q E T R +++S
Sbjct: 635 SESLHVV--------DENKNESKLEREHKRRTSTPVIME--GVQ-EETDTRDVKRQVERS 683
Query: 1141 TF--EVPENQMTILKTTSEECRDADLHVIMNAPSIGQVDSSKQ--------FEGTVEIKR 1190
E P+ Q + LK +D + + +V SSK+ E + +K
Sbjct: 684 EICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKH 743
Query: 1191 KFAGLLKNDCNKSASGYLTDENEVGFRGFYSAHGTKLNVSTEALQKAVKLFSDIENISEE 1250
K+ K DC DE E+ S G K+ + + + KL SD + +E
Sbjct: 744 KY----KGDCMHKTG----DETEL----HSSEKGLKVEENIQKQSQQTKLSSD--DKTER 789
Query: 1251 TSAEVHPISLSSSKCHDSVVSMFKIENHNDKTVSEKNNKCQLIL-------QNNIEMTTG 1303
S + LS VS + I+ D+ V ++NNK + L ++ ++
Sbjct: 790 KSKHRNERKLSVLGKDGKPVSEYIIK--TDENVRKENNKKERRLSAEKTKAEHKSRRSSD 847
Query: 1304 TFVEEITENYKRNTENEDNKYTAASRNSHNLEFDGSDSSKNDTVCIHKDETDLLFTDQHN 1363
+ +++ + K++ + + S + +++ DS+ +HK++ +
Sbjct: 848 SKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEK 907
Query: 1364 ICLKLSGQFMKEGNTQIKEDLSDLTFLEVAKAQEACHGNTSNKEQLTATKTEQNIKDFET 1423
+ LK + + ++ +L + + + NT + K++ K FE
Sbjct: 908 LVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEE 967
Query: 1424 S--DTFFQTASGKNISVAKESFNK 1445
+ + +TAS S K+S ++
Sbjct: 968 TGVEPVLETASSSAHSTQKDSSHR 991
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 43.9 bits (102), Expect = 0.003
Identities = 191/995 (19%), Positives = 390/995 (39%), Gaps = 154/995 (15%)
Query: 744 SKVEYSDTDFQSQKSLLYDHENASTLILTPTSKDVLSNLVMISRGKESYKM---SDKLKG 800
+++E +++ S L E TLI T + L + +++ K+ K S +++
Sbjct: 887 NEMEQLKEQLENRDSTLQTVEREKTLI-TEKLQQTLEEVKTLTQEKDDLKQLQESLQIER 945
Query: 801 NNYESDVELTKNIPMEKNQDVCALNENYK-NVELLPPEKYMRVASPSRKVQFNQNTN--- 856
+ +SD+ T N+ ++ + + E+ K + E + K SR + +NT
Sbjct: 946 DQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETK 1005
Query: 857 -------LRVIQKNQEETTSISKITVNPDSEELFSDNENNFVFQVANERNNL-----ALG 904
+ + +K E + +T + E+ +F + E+N L ++
Sbjct: 1006 DEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRK--IFSLIQEKNELQQMLESVI 1063
Query: 905 NTKELHETDLTCVNEPIFKNSTMV-LYGDTGDKQATQVSIKKDLVYVLAEENKNS----- 958
KE +TDL E +N + L GD KQ V+ +K+ + + +E + S
Sbjct: 1064 AEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKN--HAIKKEGELSRTCDR 1121
Query: 959 ---VKQHIKMTLGQ-DLKSDISLNIDKIPEKNNDYMNKWAGLLGPISNHSFGGSFRTASN 1014
V++ +K Q K LN+ + + +N+ L + N
Sbjct: 1122 LAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETER 1181
Query: 1015 KEI--KLSEH-----NIKKSKMFFKDIEEQYPTSL----ACVEIVNTLALDNQKKLS--- 1060
E+ KL+E+ +I K + K++++ + T + + L +++L
Sbjct: 1182 LELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAH 1241
Query: 1061 -----KPQSIN----TVSAHLQSSVVVSDCKNSHITPQ----MLFSKQDFNSNHNLTPSQ 1107
++I+ +VS + D + SH Q +L +Q+ N
Sbjct: 1242 IHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSET 1301
Query: 1108 KAEITELSTILEESGSQFEFTQFRKPSYILQ------------KSTFEVPENQMTILKTT 1155
+ + EL + E+S ++ T R L+ KS + +N TI +
Sbjct: 1302 QETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEAL 1361
Query: 1156 SEECRDADLHVIMNAPSIGQVDSSKQFEGTVEIKRKFAGLLK-----NDCNKSASGYLTD 1210
+ H+ I Q SKQ E ++ +K K K S L
Sbjct: 1362 EVKHDQLKEHIRETLAKI-QESQSKQ-EQSLNMKEKDNETTKIVSEMEQFKPKDSALLRI 1419
Query: 1211 ENEV-GF-RGFYSAHGTKLNVSTEA-----LQKAVKLFSDI--ENISE------ETSAEV 1255
E E+ G + +H +V+ E LQ+ ++ SD ENI E ET E+
Sbjct: 1420 EIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEEL 1479
Query: 1256 HPISLSSSKCHDSVVSMFKI---ENHNDKTVSEK-----NNKCQLILQNNIEMTTGTFVE 1307
++ K + ++ ++ E + + +K N+K Q +Q E ++
Sbjct: 1480 K-VAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIK 1538
Query: 1308 EITENYKRNTENEDNKYTAASRNSHNLEFDGSDSSKNDTVCIHKDETDLLFTDQHNICLK 1367
+I+E ++ E + K +++S + + + ++E ++ ++ +K
Sbjct: 1539 QISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEE--MK 1596
Query: 1368 LSGQFMKEGNTQIKEDLSDLTFLEVAKAQEACHGNTSNKEQLTATKTEQNIKDFETSDTF 1427
+ ++ Q+KE+ ++ VAK +E+ + +T++ + + E
Sbjct: 1597 RVQEALQIERDQLKENTKEI----VAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQ 1652
Query: 1428 FQTASGKNISVAKESFNKIVNFFDQKPEELHNFSLNSELHSDIRKNKMDILSYEETDIVK 1487
F+T ++ E+ ++ + EE+ + + K + D+ S EET V+
Sbjct: 1653 FETQKLNLENIETENI-RLTQILHENLEEMRS----------VTKERDDLRSVEETLKVE 1701
Query: 1488 HKILKESVPVGTGNQLVTFQGQPERDEKIKEPTLLGFHTASGKKVKIAKESLDKVKNLFD 1547
LKE N T E+ E++K ++ H +K +E++DK++ +
Sbjct: 1702 RDQLKE-------NLRETITRDLEKQEELK---IVHMH------LKEHQETIDKLRGIVS 1745
Query: 1548 EKEQGTSEITSFSHQWAKTLKY-REACKDLELACETIEITAAPKCKEMQNSLNNDKNLVS 1606
EK T+EI++ K L++ +A K +L + A KE Q +++ + +VS
Sbjct: 1746 EK---TNEISNMQ----KDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVS 1798
Query: 1607 IETVVPPKLLSDNLCRQTENLKTSKSIFLKVKVHE 1641
+T D L ++L+ S + L+ K+ E
Sbjct: 1799 EKT--------DKLSNMQKDLENSNA-KLQEKIQE 1824
Score = 37.4 bits (85), Expect = 0.26
Identities = 211/1152 (18%), Positives = 428/1152 (37%), Gaps = 186/1152 (16%)
Query: 285 KSMPNVLEDEVYETV---VDTSEEDSFSLCFSKCRTKNLQKVRTSKTRKKIFHEANADEC 341
+S + L++ + E V ++T EE + C K + + + ++R + + K+ +
Sbjct: 1455 QSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQL 1514
Query: 342 E----KSKNQVKEKYSFVSEVEPNDTDPLDSNVANQKPFESGSDKISKEVVPSLACEWSQ 397
E K +N+++E Y + + V K F+ K + S+ + +
Sbjct: 1515 EAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHR-KAKDSALQSIESKMLE 1573
Query: 398 LTLSGLNGAQMEKIPLLHISSCDQNISEKDLLDTENKRKKDFLTSENSLPRISSLPKSEK 457
LT + L +Q E+I ++ I EK+ E KR ++ L E + +
Sbjct: 1574 LT-NRLQESQ-EEIQIM--------IKEKE----EMKRVQEALQIE----------RDQL 1609
Query: 458 PLNEETVVNKRDEEQHLESHTDCILAVKQAISGTSPVASSFQGIKKSIFRIRESPKETFN 517
N + +V K E Q E + AV + + + + + E
Sbjct: 1610 KENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIR 1669
Query: 518 ASFSGHMTDPNFKKETEASESGLEIHTVCSQKEDSLCPNLIDNGSWPATTTQNSVALKNA 577
+ H + T+ + + + D L NL + T T++ +
Sbjct: 1670 LTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRE------TITRDLEKQEEL 1723
Query: 578 GLISTLKKKTNKFIYAIHDETSYKGKKIPKDQKSELINCSAQFEAN--AFEAPLTFANAD 635
++ K+ H ET K + I ++ +E+ N E + A +A +
Sbjct: 1724 KIVHMHLKE--------HQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEE 1775
Query: 636 SGLLHSSVKRSCSQNDSEEPTLSLTSSFGTILRKCSRNETCSNNTVISQDLDYKEAKCNK 695
+ H +K D +S + + SN + +DL+ AK +
Sbjct: 1776 LRIAHMHLKEQQETIDKLRGIVS------------EKTDKLSN---MQKDLENSNAKL-Q 1819
Query: 696 EKLQLFITPEADSLSCLQEGQCENDPKSKKVSDIKEEVLAAACHPVQHSKVEYSDTDFQS 755
EK+Q E L L++ E K ++ +K+++ + + SK+E + +
Sbjct: 1820 EKIQELKANE-HQLITLKKDVNETQKKVSEMEQLKKQIKDQS---LTLSKLEIENLNLAQ 1875
Query: 756 QKSLLYDHENASTLILTPTSKDVLSNLVMISRGKESYKMS-DKLKGNNYES--------- 805
+ HEN + K V+ + R +E+ K+ D+LK + E+
Sbjct: 1876 KL-----HENLEEM------KSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQ 1924
Query: 806 DVELTKNIPMEKNQDVCALNENY--KNVELLPPEKYMRVASPS--RKVQFNQNTNLRVIQ 861
+++ + + E + V L E K +++ +K + + +K+Q Q L++++
Sbjct: 1925 ELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLR 1984
Query: 862 KNQEETTSISKITVNPDSEELFSDNENNFVFQVANERNNLALGNTKELHET--------- 912
++ S KI + E+L E + + +N L TK+LHE+
Sbjct: 1985 VKEDVNMSHKKIN---EMEQLKKQFEAQNLSMQSVRMDNFQL--TKKLHESLEEIRIVAK 2039
Query: 913 ---DLTCVNEPIFKNSTMVLYG----DTGDKQATQVSIKKDLVY-----------VLAEE 954
+L + E + + D+Q QV +K L+
Sbjct: 2040 ERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSR 2099
Query: 955 NKNSVKQHIKMTLGQDLKSDISLNIDKIPEKNNDY-MNKWAGLLGPISNHSFGGSFRTAS 1013
K +K++ +M + + +SL+++K E + M A L P TA
Sbjct: 2100 IKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTA- 2158
Query: 1014 NKEIKLSEHNIKKSKMFF-----KDIEEQYPTSLACVEIVNTLALDNQKKLSKPQSINTV 1068
N+ + H I K + K EEQ+ E +N +D ++ K + +
Sbjct: 2159 NQRCSMEFHRIMKKLKYVLSYVTKIKEEQH-------ESINKFEMDFIDEVEKQKELLIK 2211
Query: 1069 SAHLQSSVVVSDCKNSHITPQMLFSKQDFNSNHNLTPSQKAEITELSTILEES-GSQFEF 1127
HLQ D + + L D + L ++E + T ++ ++ E
Sbjct: 2212 IQHLQQDC---DVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEM 2268
Query: 1128 TQFRKPSYILQKSTFEVPENQMTILKTTSEECRDADLHVIMNAPSIGQVDSSKQFEG-TV 1186
TQF + + F++ + + I K C+ ++ N I ++ S +FE +
Sbjct: 2269 TQFLEEWL---NTRFDIEKLKNGIQKENDRICQ---VNNFFNNRIIAIMNESTEFEERSA 2322
Query: 1187 EIKRKFAGLLKNDCNKSASGYLTDENEVGFRGFYS-----AHGTKLNVSTE--------- 1232
I +++ LK+ L ++NE F+ + + A G ++N +T+
Sbjct: 2323 TISKEWEQDLKS---------LKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTS 2373
Query: 1233 -ALQKAVKLFSDIEN-ISEETSAEVHPISL-----SSSKCHDSVVSMFKIENHNDKTVSE 1285
A Q + ++EN + E + +H S + + +++ + + H E
Sbjct: 2374 RATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLE 2433
Query: 1286 KNNKCQLILQNNIEMTTGTFVEEITENYKRNTENEDNKYTAASRNSHNLEFDGSDSSKND 1345
K + +LQ+ + + + EEI + + + + K A EF+ S+
Sbjct: 2434 KTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAK------EFEKEISATKA 2487
Query: 1346 TVCIHKDETDLL 1357
TV K+ LL
Sbjct: 2488 TVEYQKEVIRLL 2499
Score = 34.3 bits (77), Expect = 2.2
Identities = 45/167 (26%), Positives = 73/167 (43%), Gaps = 25/167 (14%)
Query: 2845 REEEKEAAKYVEAQQKRLEALFTKIQEEFEE-HEENTTKPYLPSRALTRQQVRALQDGAE 2903
R ++ A+ + Q LE TK+QEE HEE P + + T++ + L+ E
Sbjct: 1256 RSVSEKTAQIINTQD--LEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTE 1313
Query: 2904 LYEAVKNAADPAYLEG---------YFSEEQLRALNNHRQMLNDKKQA------QIQLEI 2948
K++ A +E S+E++++L R L K+A Q++ I
Sbjct: 1314 -QSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHI 1372
Query: 2949 R----KAMESAEQKEQGLSRDVTTVWKLRIVSYSK--KEKDSVILSI 2989
R K ES ++EQ L+ +IVS + K KDS +L I
Sbjct: 1373 RETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRI 1419
Score = 32.7 bits (73), Expect = 6.3
Identities = 46/205 (22%), Positives = 87/205 (42%), Gaps = 24/205 (11%)
Query: 2832 EKTSSGLYIFRNEREEEKEAAKYVEAQQKRLEALFTKIQEEFEEHEENTTKPYLPSRALT 2891
E+T + L + +E+E E + QK+LEA+ K+Q + +E E + + +
Sbjct: 1490 EETINELRVNLSEKETE------ISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEV 1543
Query: 2892 RQQVRALQDGAELYEAVKNAADPAYLEGYFSEEQLRALNNHRQMLNDKKQAQIQLEIRKA 2951
+++V L+ E +A +A E ++ L N Q +++ QI ++ ++
Sbjct: 1544 QEKVNELKQFKEHRKAKDSALQSI-------ESKMLELTNRLQ--ESQEEIQIMIKEKEE 1594
Query: 2952 MESAEQKEQGLSRDVTTVWKLRIVSYSK--KEKDSVILSIWRPSSDLYSLLTEGKRYRIY 3009
M+ ++ Q + RD IV+ K +EK+ L + + T+ K I
Sbjct: 1595 MKRVQEALQ-IERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNE------TQEKMCEIE 1647
Query: 3010 HLATSKSKSKSERANIQLAATKKTQ 3034
HL K NI+ + TQ
Sbjct: 1648 HLKEQFETQKLNLENIETENIRLTQ 1672
Score = 32.3 bits (72), Expect = 8.3
Identities = 63/306 (20%), Positives = 117/306 (38%), Gaps = 45/306 (14%)
Query: 1380 IKEDLSDLTFLEVAKAQEACHGNTSNKEQLTATKTEQ-NIK-DFETSDTFFQTASGKNIS 1437
I+E L D + E + SN++++T E N + D E Q + +
Sbjct: 2239 IEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQ 2298
Query: 1438 VAKESFNKIVNFFDQKPE-ELHNFSLNSELHSDIRKNKMDILSYEETDIVKHKILKESVP 1496
V N+I+ ++ E E + +++ E D++ K E ++ LK S+
Sbjct: 2299 VNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLK----EKNEKLFKNYQTLKTSLA 2354
Query: 1497 VGTG---------NQLVTFQGQPERDEKIKEPTLLGFHTAS-------GKKVKIAKESLD 1540
G N VT + EKI+E H A K +K+ KE L+
Sbjct: 2355 SGAQVNPTTQDNKNPHVTSRATQLTTEKIRELEN-SLHEAKESAMHKESKIIKMQKE-LE 2412
Query: 1541 KVKNLFDEKEQGTSEITSFSHQWAKTLK------------YREACKDLELACETIEITAA 1588
++ + + E + +T++ Y+E +DL++ I++
Sbjct: 2413 VTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKM 2472
Query: 1589 PKCKEMQNSLNNDKNLVSIETVVPPKLLSDNLCRQTENLKTSKSIFLKVKVHENVEKETA 1648
KE + ++ K V + V +LL +NL R + TS + E+ + + +
Sbjct: 2473 KNAKEFEKEISATKATVEYQKEV-IRLLRENLRRSQQAQDTS-------VISEHTDPQPS 2524
Query: 1649 KSPATC 1654
P TC
Sbjct: 2525 NKPLTC 2530
>gi|31657119 carboxypeptidase 2, cytosolic [Homo sapiens]
Length = 902
Score = 42.0 bits (97), Expect = 0.010
Identities = 65/262 (24%), Positives = 110/262 (41%), Gaps = 28/262 (10%)
Query: 263 SHGFGKTSGNSFKVNSCKDHIGKSMPNVLEDEVYETVVDTSEEDSFSLCFSKCRTKNLQK 322
S+ T G S N H L V +T++D + D F++C + L++
Sbjct: 626 SYTMESTFGGSTLGNKRDTHFTIEDLKSLGYHVCDTLLDFCDPDQMK--FTQCLAE-LKE 682
Query: 323 VRTSKTRKKIFHEANAD-ECEKSKNQVKEKYSFVSEVEPNDTDPLDSNVANQKPFESGS- 380
+ + KK FHE D + E S + + +S++E + T DS++++ P +
Sbjct: 683 LLRQEIHKK-FHELGQDVDLEGSWSDIS-----LSDIE-SSTSGSDSSLSDGLPVHLANI 735
Query: 381 -DKISKEVVPSLACEWSQLTLSGLNGAQMEKIPLLHISSCDQNISEK-DLLDTENKRKKD 438
D+++++ + L Q +K L+ ++ SEK T K+
Sbjct: 736 ADELTQKKKMFKKKKKKSLQTRKQRNEQYQKKNLMQKLKLTEDTSEKAGFASTLQKQPTF 795
Query: 439 FLTSENSLPRISSLP-KSEKPLNEETVVNKRDEEQHLESHTDCILAVKQAISGTSPVASS 497
F SENS S LP K+E P ET +N+RD++ L+ ++ P
Sbjct: 796 FKNSENS----SFLPMKNENPRLNETNLNRRDKDTPLDPSMATLIL---------PKNKG 842
Query: 498 FQGIKKSIFRIRESPKETFNAS 519
KK F + SPK T N+S
Sbjct: 843 RMQNKKPGFTVSCSPKRTINSS 864
>gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens]
Length = 1260
Score = 41.6 bits (96), Expect = 0.014
Identities = 139/750 (18%), Positives = 277/750 (36%), Gaps = 138/750 (18%)
Query: 1228 NVSTEALQKAVKLFSDIENISEETSAEV--------HPISLSSSKCHDSVVSMFKIENHN 1279
N+ ++ L S + +S + ++EV + L S+ S+V + E+H+
Sbjct: 179 NIKSKTLPDIPSSGSTTQPLSTQDNSEVLFLKENNQNVYGLDDSEHISSIVDVPPRESHS 238
Query: 1280 DKTVSEKNNKCQLILQNNIEMTTGTFVEE-----ITENYKRNTENEDNKYTAASRNSHNL 1334
S++++K L+ + + G E+ +TE KR + E N +A
Sbjct: 239 H---SDQSSKTSLMSEMRNAQSIGRRWEKPSPSNVTERKKRGSSWESNNLSA-------- 287
Query: 1335 EFDGSDSSKNDTVCIHKDETDLLFTDQHNICLKLSGQFMKEGNTQIKEDLSDLTFLEVAK 1394
DT C + + + + N +++G E NT+++ + DL L
Sbjct: 288 ----------DTPCATVLDKQHISSPELNCNNEINGH-TNETNTEMQRNKQDLPGLSSES 336
Query: 1395 AQEA---CHGNTSNKEQLTATKT---------EQNIKDFETSDTFFQTASGKNISV-AKE 1441
A+E C + + KT + T T + S K + +
Sbjct: 337 AREPNAECMNQIEDNDDFQLQKTVYDADMDLTASEVSKIVTVSTGIKKKSNKKTNEHGMK 396
Query: 1442 SFNKIVNFFDQKPEELHNFSLNSELHSDIRKNKMDILSYEETDIVKHKILKESVP-VGTG 1500
+F K+ + +K E + DI + + E +D++ K E +
Sbjct: 397 TFRKVKDSSSEKKRERSKRQFKNSSDVDIGEKIEN--RTERSDVLDGKRGAEDPGFIFNN 454
Query: 1501 NQLVTFQGQPERDEKIKEPTL-LGFHTASGKKVKIAKESLDKVKNLFDEKEQGTSEITSF 1559
QL Q + ++K+ TL GF + V K K K + +E+E+ T ++
Sbjct: 455 EQLAQMNEQLAQVNELKKMTLQTGFEQGDRENVLCNK----KEKRITNEQEE-TYSLSQS 509
Query: 1560 SHQWAKTLKYREACKDLELACETIEITAAPKCKEMQNSLNNDKNLVSIETVVPPKLLSDN 1619
S ++ + K+ + QNSL +K+ S +T V KL DN
Sbjct: 510 SGKFHQESKFDKG----------------------QNSLTCNKSKASRQTFVIHKLEKDN 547
Query: 1620 LCRQTENLKTSKSIFLKVKVHENVEKETAKSPATCYTNQSPYSVIENSALAFYTSCSRKT 1679
L ++ KV ++EN++ T + + S +N L Y
Sbjct: 548 LLPNQKD---------KVTIYENLD-------VTNEFHTANLSTKDNGNLCDY------- 584
Query: 1680 SVSQTSLLEAKKWLREGIFDGQPERINTADYVGNYLYENNSNSTIAENDKNHLSEKQDTY 1739
++L+ KK+ + D QP N ++ N L + + T + NH+ E D
Sbjct: 585 --GTHNILDLKKY----VTDIQPSEQNESNI--NKLRKKVNRKTEIISGMNHMYEDNDKD 636
Query: 1740 LSNSSMSNSYSYHSDEVYNDSGYLSKNKLDSGIEPVLKNVEDQKNTSFSKVISNVKDANA 1799
+ + ++ + + E EP+ +N+E K +S + N
Sbjct: 637 VVHGLKKGNFFFKTQE---------------DKEPISENIEVSKELQI-PALSTRDNENQ 680
Query: 1800 YPQTVNEDICVEELVTSSSPCKNKNAAI--KLSISNSNNFEVGPPAFRIASGKIVCVSHE 1857
+ +++ +T+ P + + + KL + E+ + + K +
Sbjct: 681 CDYRTQNVLGLQKQITNMYPVQQNESKVNKKLRQKVNRKTEIISEVNHLDNDKSI---EY 737
Query: 1858 TIKKVKDIFTDSFSKVIKENNENKSKICQTKIMAGCYEALDDSEDILHNSLDNDECSTHS 1917
T+K T ++I N E+ S+ +T + + DS ++ + + N H
Sbjct: 738 TVKSHSLFLTQKDKEIIPGNLEDPSEF-ETPAL-----STKDSGNLYDSEIQNVLGVKHG 791
Query: 1918 HKVFADIQSEEILQHNQNMSGLEKVSKISP 1947
H + Q++ + ++ +K S+I P
Sbjct: 792 HDMQPACQNDSKIGKKPRLNVCQK-SEIIP 820
Score = 37.4 bits (85), Expect = 0.26
Identities = 198/1050 (18%), Positives = 390/1050 (37%), Gaps = 191/1050 (18%)
Query: 419 CDQNISEKDLLDTENKRKKDFLTSENSLPRISSLPKSEKPLNEETVVNKR--DEEQHLES 476
CD NI K L D +S ++ +S+ SE +E N D+ +H+ S
Sbjct: 176 CDNNIKSKTL--------PDIPSSGSTTQPLSTQDNSEVLFLKENNQNVYGLDDSEHISS 227
Query: 477 HTDCILAVKQAISGTSPVASSFQGIK--KSIFRIRESPKETFNASFSGHMTDPNFKKETE 534
D + S S S ++ +SI R E P + ++T+ K+ +
Sbjct: 228 IVDVPPRESHSHSDQSSKTSLMSEMRNAQSIGRRWEKPSPS-------NVTERK-KRGSS 279
Query: 535 ASESGLEIHTVCS---QKEDSLCPNLIDNGSWPATTTQNSVALKN-----AGLISTLKKK 586
+ L T C+ K+ P L N T + + ++ GL S ++
Sbjct: 280 WESNNLSADTPCATVLDKQHISSPELNCNNEINGHTNETNTEMQRNKQDLPGLSSESARE 339
Query: 587 TN-KFIYAIHDETSYKGKKIPKD--------QKSELINCSAQFEANAFEAPLTFANADSG 637
N + + I D ++ +K D + S+++ S + + + N
Sbjct: 340 PNAECMNQIEDNDDFQLQKTVYDADMDLTASEVSKIVTVSTGIKKKSNKK----TNEHGM 395
Query: 638 LLHSSVKRSCSQNDSEEPTLSLTSSFGTILRKCSRNETCSNNTVISQDLDYKE------- 690
VK S S+ E +S + E N T S LD K
Sbjct: 396 KTFRKVKDSSSEKKRERSKRQFKNSSDVDI-----GEKIENRTERSDVLDGKRGAEDPGF 450
Query: 691 -------AKCNKEKLQLFITPEADSLSCLQEGQCEN---DPKSKKVSDIKEEVLAAACHP 740
A+ N++ Q+ + + ++G EN + K K++++ +EE + +
Sbjct: 451 IFNNEQLAQMNEQLAQVNELKKMTLQTGFEQGDRENVLCNKKEKRITNEQEETYSLS--- 507
Query: 741 VQHSKVEYSDTDF-QSQKSLLYDHENAS--TLILTPTSKDVLSNLVMISRGKESYKMSDK 797
Q S + ++ F + Q SL + AS T ++ KD L + K+ + +
Sbjct: 508 -QSSGKFHQESKFDKGQNSLTCNKSKASRQTFVIHKLEKDNL-----LPNQKDKVTIYEN 561
Query: 798 LKGNNYESDVELTKNIPMEKNQDVCALNENYKNVELLPPEKYMRVASPSRKVQFNQNTNL 857
L N T N+ + N ++C +Y +L +KY+ PS + + N N
Sbjct: 562 LDVTNEFH----TANLSTKDNGNLC----DYGTHNILDLKKYVTDIQPSEQNESNINKLR 613
Query: 858 RVIQKNQEETTSISKITVNPDSEELFSDNENNFVFQVANERNNLA--LGNTKELHETDL- 914
+ + + E + ++ + + D + + + NF F+ ++ ++ + +KEL L
Sbjct: 614 KKVNRKTEIISGMNHMYEDNDKDVVHGLKKGNFFFKTQEDKEPISENIEVSKELQIPALS 673
Query: 915 TCVNEPIFKNSTMVLYGDTGDKQATQVSIKKDLVYVLAEENKNSVKQHIKMTLGQDLKSD 974
T NE T + G KQ T + ++N++ V + ++ + + K++
Sbjct: 674 TRDNENQCDYRTQNVLG--LQKQITNM--------YPVQQNESKVNKKLRQKVNR--KTE 721
Query: 975 ISLNIDKIPEKNNDYMNKWAGLLGPISNHSFGGSFRTASNKEIKLSEHNIKKSKMFFKDI 1034
I I ++ +ND ++ + +HS F T +KEI + + S+ +
Sbjct: 722 I---ISEVNHLDNDKSIEYT-----VKSHSL---FLTQKDKEI-IPGNLEDPSEFETPAL 769
Query: 1035 EEQYPTSLACVEIVNTL----------ALDNQKKLSKPQSINTVSAHLQSSVVVSDCKNS 1084
+ +L EI N L A N K+ K +N Q S ++ +
Sbjct: 770 STKDSGNLYDSEIQNVLGVKHGHDMQPACQNDSKIGKKPRLNV----CQKSEIIPETNQI 825
Query: 1085 HITPQMLFSKQDFNSNHNLTPSQKAEITE----------LSTILEESGSQFEF-TQ--FR 1131
+ + ++ +LTP K I+E + +++++G+ ++ TQ
Sbjct: 826 YENDNKGVHDLEKDNFFSLTPKDKETISENLQVTNEFQTVDLLIKDNGNLCDYDTQNILE 885
Query: 1132 KPSYILQKSTFEVPENQMTILKTTSE-------------ECRDADLHV--IMNAPSIGQV 1176
Y+ + + E E+++ L+ E D D HV +V
Sbjct: 886 LKKYVTDRKSAEQNESKINKLRNKVNWKTEIISEMNQIYEDNDKDAHVQESYTKDLDFKV 945
Query: 1177 DSSKQ-FEGTVEIKRKFAGLLKND---CNKSASGYLT-----DENEVGFRGFYSAHGTKL 1227
+ SKQ E I + + + N+ C++ Y E+ + + KL
Sbjct: 946 NKSKQKLECQDIINKHYMEVNSNEKESCDQILDSYKVVKKRKKESSCKAKNILTKAKNKL 1005
Query: 1228 -NVSTEALQKAVKLFSDIENISEETSAEV-HPISL----------------------SSS 1263
+ TE+ Q ++ L SD+++I+ E ++ +P+ L
Sbjct: 1006 ASQLTESSQTSISLESDLKHITSEADSDPGNPVELCKTQKQSTTTLNKKDLPFVEEIKEG 1065
Query: 1264 KCHDSVVSMFKIENHNDKTVSEKNNKCQLILQNNIEMTTGTFVEEITENYKRNTENE--- 1320
+C V+ ++ KT + + + +++ ++ G + + N ENE
Sbjct: 1066 ECQVKKVNKMTSKSKKRKTSIDPSPESHEVMERILDSVQGKSTVSEQADKENNLENEKMV 1125
Query: 1321 DNK---YTAASRNSHNLEFDGSDSSKNDTV 1347
NK YT A R+ + S D+V
Sbjct: 1126 KNKPDFYTKAFRSLSEIHSPNIQDSSFDSV 1155
>gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens]
Length = 1265
Score = 41.6 bits (96), Expect = 0.014
Identities = 139/750 (18%), Positives = 277/750 (36%), Gaps = 138/750 (18%)
Query: 1228 NVSTEALQKAVKLFSDIENISEETSAEV--------HPISLSSSKCHDSVVSMFKIENHN 1279
N+ ++ L S + +S + ++EV + L S+ S+V + E+H+
Sbjct: 179 NIKSKTLPDIPSSGSTTQPLSTQDNSEVLFLKENNQNVYGLDDSEHISSIVDVPPRESHS 238
Query: 1280 DKTVSEKNNKCQLILQNNIEMTTGTFVEE-----ITENYKRNTENEDNKYTAASRNSHNL 1334
S++++K L+ + + G E+ +TE KR + E N +A
Sbjct: 239 H---SDQSSKTSLMSEMRNAQSIGRRWEKPSPSNVTERKKRGSSWESNNLSA-------- 287
Query: 1335 EFDGSDSSKNDTVCIHKDETDLLFTDQHNICLKLSGQFMKEGNTQIKEDLSDLTFLEVAK 1394
DT C + + + + N +++G E NT+++ + DL L
Sbjct: 288 ----------DTPCATVLDKQHISSPELNCNNEINGH-TNETNTEMQRNKQDLPGLSSES 336
Query: 1395 AQEA---CHGNTSNKEQLTATKT---------EQNIKDFETSDTFFQTASGKNISV-AKE 1441
A+E C + + KT + T T + S K + +
Sbjct: 337 AREPNAECMNQIEDNDDFQLQKTVYDADMDLTASEVSKIVTVSTGIKKKSNKKTNEHGMK 396
Query: 1442 SFNKIVNFFDQKPEELHNFSLNSELHSDIRKNKMDILSYEETDIVKHKILKESVP-VGTG 1500
+F K+ + +K E + DI + + E +D++ K E +
Sbjct: 397 TFRKVKDSSSEKKRERSKRQFKNSSDVDIGEKIEN--RTERSDVLDGKRGAEDPGFIFNN 454
Query: 1501 NQLVTFQGQPERDEKIKEPTL-LGFHTASGKKVKIAKESLDKVKNLFDEKEQGTSEITSF 1559
QL Q + ++K+ TL GF + V K K K + +E+E+ T ++
Sbjct: 455 EQLAQMNEQLAQVNELKKMTLQTGFEQGDRENVLCNK----KEKRITNEQEE-TYSLSQS 509
Query: 1560 SHQWAKTLKYREACKDLELACETIEITAAPKCKEMQNSLNNDKNLVSIETVVPPKLLSDN 1619
S ++ + K+ + QNSL +K+ S +T V KL DN
Sbjct: 510 SGKFHQESKFDKG----------------------QNSLTCNKSKASRQTFVIHKLEKDN 547
Query: 1620 LCRQTENLKTSKSIFLKVKVHENVEKETAKSPATCYTNQSPYSVIENSALAFYTSCSRKT 1679
L ++ KV ++EN++ T + + S +N L Y
Sbjct: 548 LLPNQKD---------KVTIYENLD-------VTNEFHTANLSTKDNGNLCDY------- 584
Query: 1680 SVSQTSLLEAKKWLREGIFDGQPERINTADYVGNYLYENNSNSTIAENDKNHLSEKQDTY 1739
++L+ KK+ + D QP N ++ N L + + T + NH+ E D
Sbjct: 585 --GTHNILDLKKY----VTDIQPSEQNESNI--NKLRKKVNRKTEIISGMNHMYEDNDKD 636
Query: 1740 LSNSSMSNSYSYHSDEVYNDSGYLSKNKLDSGIEPVLKNVEDQKNTSFSKVISNVKDANA 1799
+ + ++ + + E EP+ +N+E K +S + N
Sbjct: 637 VVHGLKKGNFFFKTQE---------------DKEPISENIEVSKELQI-PALSTRDNENQ 680
Query: 1800 YPQTVNEDICVEELVTSSSPCKNKNAAI--KLSISNSNNFEVGPPAFRIASGKIVCVSHE 1857
+ +++ +T+ P + + + KL + E+ + + K +
Sbjct: 681 CDYRTQNVLGLQKQITNMYPVQQNESKVNKKLRQKVNRKTEIISEVNHLDNDKSI---EY 737
Query: 1858 TIKKVKDIFTDSFSKVIKENNENKSKICQTKIMAGCYEALDDSEDILHNSLDNDECSTHS 1917
T+K T ++I N E+ S+ +T + + DS ++ + + N H
Sbjct: 738 TVKSHSLFLTQKDKEIIPGNLEDPSEF-ETPAL-----STKDSGNLYDSEIQNVLGVKHG 791
Query: 1918 HKVFADIQSEEILQHNQNMSGLEKVSKISP 1947
H + Q++ + ++ +K S+I P
Sbjct: 792 HDMQPACQNDSKIGKKPRLNVCQK-SEIIP 820
Score = 37.4 bits (85), Expect = 0.26
Identities = 198/1050 (18%), Positives = 390/1050 (37%), Gaps = 191/1050 (18%)
Query: 419 CDQNISEKDLLDTENKRKKDFLTSENSLPRISSLPKSEKPLNEETVVNKR--DEEQHLES 476
CD NI K L D +S ++ +S+ SE +E N D+ +H+ S
Sbjct: 176 CDNNIKSKTL--------PDIPSSGSTTQPLSTQDNSEVLFLKENNQNVYGLDDSEHISS 227
Query: 477 HTDCILAVKQAISGTSPVASSFQGIK--KSIFRIRESPKETFNASFSGHMTDPNFKKETE 534
D + S S S ++ +SI R E P + ++T+ K+ +
Sbjct: 228 IVDVPPRESHSHSDQSSKTSLMSEMRNAQSIGRRWEKPSPS-------NVTERK-KRGSS 279
Query: 535 ASESGLEIHTVCS---QKEDSLCPNLIDNGSWPATTTQNSVALKN-----AGLISTLKKK 586
+ L T C+ K+ P L N T + + ++ GL S ++
Sbjct: 280 WESNNLSADTPCATVLDKQHISSPELNCNNEINGHTNETNTEMQRNKQDLPGLSSESARE 339
Query: 587 TN-KFIYAIHDETSYKGKKIPKD--------QKSELINCSAQFEANAFEAPLTFANADSG 637
N + + I D ++ +K D + S+++ S + + + N
Sbjct: 340 PNAECMNQIEDNDDFQLQKTVYDADMDLTASEVSKIVTVSTGIKKKSNKK----TNEHGM 395
Query: 638 LLHSSVKRSCSQNDSEEPTLSLTSSFGTILRKCSRNETCSNNTVISQDLDYKE------- 690
VK S S+ E +S + E N T S LD K
Sbjct: 396 KTFRKVKDSSSEKKRERSKRQFKNSSDVDI-----GEKIENRTERSDVLDGKRGAEDPGF 450
Query: 691 -------AKCNKEKLQLFITPEADSLSCLQEGQCEN---DPKSKKVSDIKEEVLAAACHP 740
A+ N++ Q+ + + ++G EN + K K++++ +EE + +
Sbjct: 451 IFNNEQLAQMNEQLAQVNELKKMTLQTGFEQGDRENVLCNKKEKRITNEQEETYSLS--- 507
Query: 741 VQHSKVEYSDTDF-QSQKSLLYDHENAS--TLILTPTSKDVLSNLVMISRGKESYKMSDK 797
Q S + ++ F + Q SL + AS T ++ KD L + K+ + +
Sbjct: 508 -QSSGKFHQESKFDKGQNSLTCNKSKASRQTFVIHKLEKDNL-----LPNQKDKVTIYEN 561
Query: 798 LKGNNYESDVELTKNIPMEKNQDVCALNENYKNVELLPPEKYMRVASPSRKVQFNQNTNL 857
L N T N+ + N ++C +Y +L +KY+ PS + + N N
Sbjct: 562 LDVTNEFH----TANLSTKDNGNLC----DYGTHNILDLKKYVTDIQPSEQNESNINKLR 613
Query: 858 RVIQKNQEETTSISKITVNPDSEELFSDNENNFVFQVANERNNLA--LGNTKELHETDL- 914
+ + + E + ++ + + D + + + NF F+ ++ ++ + +KEL L
Sbjct: 614 KKVNRKTEIISGMNHMYEDNDKDVVHGLKKGNFFFKTQEDKEPISENIEVSKELQIPALS 673
Query: 915 TCVNEPIFKNSTMVLYGDTGDKQATQVSIKKDLVYVLAEENKNSVKQHIKMTLGQDLKSD 974
T NE T + G KQ T + ++N++ V + ++ + + K++
Sbjct: 674 TRDNENQCDYRTQNVLG--LQKQITNM--------YPVQQNESKVNKKLRQKVNR--KTE 721
Query: 975 ISLNIDKIPEKNNDYMNKWAGLLGPISNHSFGGSFRTASNKEIKLSEHNIKKSKMFFKDI 1034
I I ++ +ND ++ + +HS F T +KEI + + S+ +
Sbjct: 722 I---ISEVNHLDNDKSIEYT-----VKSHSL---FLTQKDKEI-IPGNLEDPSEFETPAL 769
Query: 1035 EEQYPTSLACVEIVNTL----------ALDNQKKLSKPQSINTVSAHLQSSVVVSDCKNS 1084
+ +L EI N L A N K+ K +N Q S ++ +
Sbjct: 770 STKDSGNLYDSEIQNVLGVKHGHDMQPACQNDSKIGKKPRLNV----CQKSEIIPETNQI 825
Query: 1085 HITPQMLFSKQDFNSNHNLTPSQKAEITE----------LSTILEESGSQFEF-TQ--FR 1131
+ + ++ +LTP K I+E + +++++G+ ++ TQ
Sbjct: 826 YENDNKGVHDLEKDNFFSLTPKDKETISENLQVTNEFQTVDLLIKDNGNLCDYDTQNILE 885
Query: 1132 KPSYILQKSTFEVPENQMTILKTTSE-------------ECRDADLHV--IMNAPSIGQV 1176
Y+ + + E E+++ L+ E D D HV +V
Sbjct: 886 LKKYVTDRKSAEQNESKINKLRNKVNWKTEIISEMNQIYEDNDKDAHVQESYTKDLDFKV 945
Query: 1177 DSSKQ-FEGTVEIKRKFAGLLKND---CNKSASGYLT-----DENEVGFRGFYSAHGTKL 1227
+ SKQ E I + + + N+ C++ Y E+ + + KL
Sbjct: 946 NKSKQKLECQDIINKHYMEVNSNEKESCDQILDSYKVVKKRKKESSCKAKNILTKAKNKL 1005
Query: 1228 -NVSTEALQKAVKLFSDIENISEETSAEV-HPISL----------------------SSS 1263
+ TE+ Q ++ L SD+++I+ E ++ +P+ L
Sbjct: 1006 ASQLTESSQTSISLESDLKHITSEADSDPGNPVELCKTQKQSTTTLNKKDLPFVEEIKEG 1065
Query: 1264 KCHDSVVSMFKIENHNDKTVSEKNNKCQLILQNNIEMTTGTFVEEITENYKRNTENE--- 1320
+C V+ ++ KT + + + +++ ++ G + + N ENE
Sbjct: 1066 ECQVKKVNKMTSKSKKRKTSIDPSPESHEVMERILDSVQGKSTVSEQADKENNLENEKMV 1125
Query: 1321 DNK---YTAASRNSHNLEFDGSDSSKNDTV 1347
NK YT A R+ + S D+V
Sbjct: 1126 KNKPDFYTKAFRSLSEIHSPNIQDSSFDSV 1155
>gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens]
Length = 1261
Score = 41.6 bits (96), Expect = 0.014
Identities = 139/750 (18%), Positives = 277/750 (36%), Gaps = 138/750 (18%)
Query: 1228 NVSTEALQKAVKLFSDIENISEETSAEV--------HPISLSSSKCHDSVVSMFKIENHN 1279
N+ ++ L S + +S + ++EV + L S+ S+V + E+H+
Sbjct: 179 NIKSKTLPDIPSSGSTTQPLSTQDNSEVLFLKENNQNVYGLDDSEHISSIVDVPPRESHS 238
Query: 1280 DKTVSEKNNKCQLILQNNIEMTTGTFVEE-----ITENYKRNTENEDNKYTAASRNSHNL 1334
S++++K L+ + + G E+ +TE KR + E N +A
Sbjct: 239 H---SDQSSKTSLMSEMRNAQSIGRRWEKPSPSNVTERKKRGSSWESNNLSA-------- 287
Query: 1335 EFDGSDSSKNDTVCIHKDETDLLFTDQHNICLKLSGQFMKEGNTQIKEDLSDLTFLEVAK 1394
DT C + + + + N +++G E NT+++ + DL L
Sbjct: 288 ----------DTPCATVLDKQHISSPELNCNNEINGH-TNETNTEMQRNKQDLPGLSSES 336
Query: 1395 AQEA---CHGNTSNKEQLTATKT---------EQNIKDFETSDTFFQTASGKNISV-AKE 1441
A+E C + + KT + T T + S K + +
Sbjct: 337 AREPNAECMNQIEDNDDFQLQKTVYDADMDLTASEVSKIVTVSTGIKKKSNKKTNEHGMK 396
Query: 1442 SFNKIVNFFDQKPEELHNFSLNSELHSDIRKNKMDILSYEETDIVKHKILKESVP-VGTG 1500
+F K+ + +K E + DI + + E +D++ K E +
Sbjct: 397 TFRKVKDSSSEKKRERSKRQFKNSSDVDIGEKIEN--RTERSDVLDGKRGAEDPGFIFNN 454
Query: 1501 NQLVTFQGQPERDEKIKEPTL-LGFHTASGKKVKIAKESLDKVKNLFDEKEQGTSEITSF 1559
QL Q + ++K+ TL GF + V K K K + +E+E+ T ++
Sbjct: 455 EQLAQMNEQLAQVNELKKMTLQTGFEQGDRENVLCNK----KEKRITNEQEE-TYSLSQS 509
Query: 1560 SHQWAKTLKYREACKDLELACETIEITAAPKCKEMQNSLNNDKNLVSIETVVPPKLLSDN 1619
S ++ + K+ + QNSL +K+ S +T V KL DN
Sbjct: 510 SGKFHQESKFDKG----------------------QNSLTCNKSKASRQTFVIHKLEKDN 547
Query: 1620 LCRQTENLKTSKSIFLKVKVHENVEKETAKSPATCYTNQSPYSVIENSALAFYTSCSRKT 1679
L ++ KV ++EN++ T + + S +N L Y
Sbjct: 548 LLPNQKD---------KVTIYENLD-------VTNEFHTANLSTKDNGNLCDY------- 584
Query: 1680 SVSQTSLLEAKKWLREGIFDGQPERINTADYVGNYLYENNSNSTIAENDKNHLSEKQDTY 1739
++L+ KK+ + D QP N ++ N L + + T + NH+ E D
Sbjct: 585 --GTHNILDLKKY----VTDIQPSEQNESNI--NKLRKKVNRKTEIISGMNHMYEDNDKD 636
Query: 1740 LSNSSMSNSYSYHSDEVYNDSGYLSKNKLDSGIEPVLKNVEDQKNTSFSKVISNVKDANA 1799
+ + ++ + + E EP+ +N+E K +S + N
Sbjct: 637 VVHGLKKGNFFFKTQE---------------DKEPISENIEVSKELQI-PALSTRDNENQ 680
Query: 1800 YPQTVNEDICVEELVTSSSPCKNKNAAI--KLSISNSNNFEVGPPAFRIASGKIVCVSHE 1857
+ +++ +T+ P + + + KL + E+ + + K +
Sbjct: 681 CDYRTQNVLGLQKQITNMYPVQQNESKVNKKLRQKVNRKTEIISEVNHLDNDKSI---EY 737
Query: 1858 TIKKVKDIFTDSFSKVIKENNENKSKICQTKIMAGCYEALDDSEDILHNSLDNDECSTHS 1917
T+K T ++I N E+ S+ +T + + DS ++ + + N H
Sbjct: 738 TVKSHSLFLTQKDKEIIPGNLEDPSEF-ETPAL-----STKDSGNLYDSEIQNVLGVKHG 791
Query: 1918 HKVFADIQSEEILQHNQNMSGLEKVSKISP 1947
H + Q++ + ++ +K S+I P
Sbjct: 792 HDMQPACQNDSKIGKKPRLNVCQK-SEIIP 820
Score = 37.4 bits (85), Expect = 0.26
Identities = 198/1050 (18%), Positives = 390/1050 (37%), Gaps = 191/1050 (18%)
Query: 419 CDQNISEKDLLDTENKRKKDFLTSENSLPRISSLPKSEKPLNEETVVNKR--DEEQHLES 476
CD NI K L D +S ++ +S+ SE +E N D+ +H+ S
Sbjct: 176 CDNNIKSKTL--------PDIPSSGSTTQPLSTQDNSEVLFLKENNQNVYGLDDSEHISS 227
Query: 477 HTDCILAVKQAISGTSPVASSFQGIK--KSIFRIRESPKETFNASFSGHMTDPNFKKETE 534
D + S S S ++ +SI R E P + ++T+ K+ +
Sbjct: 228 IVDVPPRESHSHSDQSSKTSLMSEMRNAQSIGRRWEKPSPS-------NVTERK-KRGSS 279
Query: 535 ASESGLEIHTVCS---QKEDSLCPNLIDNGSWPATTTQNSVALKN-----AGLISTLKKK 586
+ L T C+ K+ P L N T + + ++ GL S ++
Sbjct: 280 WESNNLSADTPCATVLDKQHISSPELNCNNEINGHTNETNTEMQRNKQDLPGLSSESARE 339
Query: 587 TN-KFIYAIHDETSYKGKKIPKD--------QKSELINCSAQFEANAFEAPLTFANADSG 637
N + + I D ++ +K D + S+++ S + + + N
Sbjct: 340 PNAECMNQIEDNDDFQLQKTVYDADMDLTASEVSKIVTVSTGIKKKSNKK----TNEHGM 395
Query: 638 LLHSSVKRSCSQNDSEEPTLSLTSSFGTILRKCSRNETCSNNTVISQDLDYKE------- 690
VK S S+ E +S + E N T S LD K
Sbjct: 396 KTFRKVKDSSSEKKRERSKRQFKNSSDVDI-----GEKIENRTERSDVLDGKRGAEDPGF 450
Query: 691 -------AKCNKEKLQLFITPEADSLSCLQEGQCEN---DPKSKKVSDIKEEVLAAACHP 740
A+ N++ Q+ + + ++G EN + K K++++ +EE + +
Sbjct: 451 IFNNEQLAQMNEQLAQVNELKKMTLQTGFEQGDRENVLCNKKEKRITNEQEETYSLS--- 507
Query: 741 VQHSKVEYSDTDF-QSQKSLLYDHENAS--TLILTPTSKDVLSNLVMISRGKESYKMSDK 797
Q S + ++ F + Q SL + AS T ++ KD L + K+ + +
Sbjct: 508 -QSSGKFHQESKFDKGQNSLTCNKSKASRQTFVIHKLEKDNL-----LPNQKDKVTIYEN 561
Query: 798 LKGNNYESDVELTKNIPMEKNQDVCALNENYKNVELLPPEKYMRVASPSRKVQFNQNTNL 857
L N T N+ + N ++C +Y +L +KY+ PS + + N N
Sbjct: 562 LDVTNEFH----TANLSTKDNGNLC----DYGTHNILDLKKYVTDIQPSEQNESNINKLR 613
Query: 858 RVIQKNQEETTSISKITVNPDSEELFSDNENNFVFQVANERNNLA--LGNTKELHETDL- 914
+ + + E + ++ + + D + + + NF F+ ++ ++ + +KEL L
Sbjct: 614 KKVNRKTEIISGMNHMYEDNDKDVVHGLKKGNFFFKTQEDKEPISENIEVSKELQIPALS 673
Query: 915 TCVNEPIFKNSTMVLYGDTGDKQATQVSIKKDLVYVLAEENKNSVKQHIKMTLGQDLKSD 974
T NE T + G KQ T + ++N++ V + ++ + + K++
Sbjct: 674 TRDNENQCDYRTQNVLG--LQKQITNM--------YPVQQNESKVNKKLRQKVNR--KTE 721
Query: 975 ISLNIDKIPEKNNDYMNKWAGLLGPISNHSFGGSFRTASNKEIKLSEHNIKKSKMFFKDI 1034
I I ++ +ND ++ + +HS F T +KEI + + S+ +
Sbjct: 722 I---ISEVNHLDNDKSIEYT-----VKSHSL---FLTQKDKEI-IPGNLEDPSEFETPAL 769
Query: 1035 EEQYPTSLACVEIVNTL----------ALDNQKKLSKPQSINTVSAHLQSSVVVSDCKNS 1084
+ +L EI N L A N K+ K +N Q S ++ +
Sbjct: 770 STKDSGNLYDSEIQNVLGVKHGHDMQPACQNDSKIGKKPRLNV----CQKSEIIPETNQI 825
Query: 1085 HITPQMLFSKQDFNSNHNLTPSQKAEITE----------LSTILEESGSQFEF-TQ--FR 1131
+ + ++ +LTP K I+E + +++++G+ ++ TQ
Sbjct: 826 YENDNKGVHDLEKDNFFSLTPKDKETISENLQVTNEFQTVDLLIKDNGNLCDYDTQNILE 885
Query: 1132 KPSYILQKSTFEVPENQMTILKTTSE-------------ECRDADLHV--IMNAPSIGQV 1176
Y+ + + E E+++ L+ E D D HV +V
Sbjct: 886 LKKYVTDRKSAEQNESKINKLRNKVNWKTEIISEMNQIYEDNDKDAHVQESYTKDLDFKV 945
Query: 1177 DSSKQ-FEGTVEIKRKFAGLLKND---CNKSASGYLT-----DENEVGFRGFYSAHGTKL 1227
+ SKQ E I + + + N+ C++ Y E+ + + KL
Sbjct: 946 NKSKQKLECQDIINKHYMEVNSNEKESCDQILDSYKVVKKRKKESSCKAKNILTKAKNKL 1005
Query: 1228 -NVSTEALQKAVKLFSDIENISEETSAEV-HPISL----------------------SSS 1263
+ TE+ Q ++ L SD+++I+ E ++ +P+ L
Sbjct: 1006 ASQLTESSQTSISLESDLKHITSEADSDPGNPVELCKTQKQSTTTLNKKDLPFVEEIKEG 1065
Query: 1264 KCHDSVVSMFKIENHNDKTVSEKNNKCQLILQNNIEMTTGTFVEEITENYKRNTENE--- 1320
+C V+ ++ KT + + + +++ ++ G + + N ENE
Sbjct: 1066 ECQVKKVNKMTSKSKKRKTSIDPSPESHEVMERILDSVQGKSTVSEQADKENNLENEKMV 1125
Query: 1321 DNK---YTAASRNSHNLEFDGSDSSKNDTV 1347
NK YT A R+ + S D+V
Sbjct: 1126 KNKPDFYTKAFRSLSEIHSPNIQDSSFDSV 1155
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 40.8 bits (94), Expect = 0.023
Identities = 76/355 (21%), Positives = 136/355 (38%), Gaps = 23/355 (6%)
Query: 1717 ENNSNSTIAENDKNHLSEKQDTYLSNSSMSNSYSYHSDEVYNDSGYLSKNKLDSGIEPVL 1776
++ S+S+ +E+D + K D+ SNSS S+ S SD + + S + DS
Sbjct: 621 DSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680
Query: 1777 KNVEDQKNTSFSKVISNVKDANAYPQTVNEDICVEELVTSSSPCKNKNAAIKLSISNSNN 1836
+ + ++S S SN +++ + + D + SS N N++ S ++S++
Sbjct: 681 SDSSNSSDSSDSSDSSNSSESSDSSDSSDSD------SSDSSDSSNSNSSDSDSSNSSDS 734
Query: 1837 FEVGPPAFRIASGKIVCVSHETIKKVKDIFTDSFSKVIKENNENKSKICQTKIMAGCYEA 1896
+ S S + +DS ++ + S + + ++
Sbjct: 735 SD---------SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785
Query: 1897 LDDSEDILHNSLDNDECSTHSHKVFADIQSEEILQHNQNMSGLEKVSKISPCDVSLETSD 1956
D S +S D+ S S+ + S+ + N S S S S ++SD
Sbjct: 786 NDSSNS--SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD 843
Query: 1957 ICKCSIG----KLHKSVSSANTCGIFSTASGKSVQVSDASLQNARQVFSEIEDSTKQVFS 2012
S G ++S SS ++ S+ S S SD+S N S+ DS+ S
Sbjct: 844 SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDS 903
Query: 2013 KVLFKSNEHSDQLTREENTAIRTPEHLISQKGFSYNVVNSSAFSGFSTASGKQVS 2067
SN S + N++ + S S + NSS S S +S S
Sbjct: 904 DSSDSSN--SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 956
Score = 36.2 bits (82), Expect = 0.57
Identities = 63/307 (20%), Positives = 121/307 (39%), Gaps = 14/307 (4%)
Query: 1717 ENNSNSTIAENDKNHLSEKQDTYLSNSSMSNSYSYHSDEVYNDSGYLSKNKLDSGIEPVL 1776
+++ +S +++D + S D+ S++S +S S +S + N S S N DS
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD--SSNSSDSSDSSDS 950
Query: 1777 KNVEDQKNTSFSKVISNVKDANAYPQTVNEDICVEELVTSSSPCKNKNAAIKLSISNSNN 1836
N D N+S S S+ D+N+ + + + +S S + ++ S +SN+
Sbjct: 951 SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN-------SSDSSDSSDSSDSSDSSDSSNS 1003
Query: 1837 FEVGPPAFRIASGKIVCVSHETIKKVKDIFTDSFSKVIKENNENKSKICQTKIMAGCYEA 1896
+ + S S+ + +DS ++ + S + + ++
Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063
Query: 1897 LDDSEDILHNSLDNDECSTHSHKVFADIQSEEILQHNQNMSGLEKVSKISPCDVSLETSD 1956
D S+ +S D+ + S S +D + + S S S S ++SD
Sbjct: 1064 SDSSDS--SDSSDSSDSSDSSES--SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1119
Query: 1957 ICKCSIGKLHKSVSSANTCGIFSTASGKSVQVSDASLQNARQVFSEIEDSTKQVFSKVLF 2016
S S SS ++ S+ S S + SD+S + S+ DS+ S
Sbjct: 1120 SSNSS-DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178
Query: 2017 KSNEHSD 2023
S++ SD
Sbjct: 1179 NSSDSSD 1185
Score = 35.4 bits (80), Expect = 0.98
Identities = 87/440 (19%), Positives = 162/440 (36%), Gaps = 25/440 (5%)
Query: 1718 NNSNST---IAENDKNHLSE----KQDTYLSNSSMSNSYSYHSDEVYNDSGYLSKNKLDS 1770
NNS+S ND N S+ K D+ S+SS S++ S SD +DS + +
Sbjct: 522 NNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSD 581
Query: 1771 GIEPVLKNVEDQKNTSFSKVISNVKDANAYPQTVNEDICVEELVTSSSPCKNKNAAIKLS 1830
+ + D ++ S + +++ + + D + +S S + ++ K
Sbjct: 582 SSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSD 641
Query: 1831 ISNSNNFEVGPPAFRIASGKIVCVSHETIKKVKDIFTDSFSKVIKENNENKSKICQTKIM 1890
S+SN+ + + S S+ + +DS ++ N S +
Sbjct: 642 SSDSNSSDSSDNSDSSDS------SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695
Query: 1891 AGCYEALDDSEDILHNSLDNDECSTHSHKVFADIQSEEILQHNQNMSGLEKVSKISPCDV 1950
+ E+ D S+ +S D+ + S++S+ +D + + N S S S
Sbjct: 696 SNSSESSDSSDSSDSDSSDSSD-SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSD 754
Query: 1951 SLETSDICKC--SIGKLHKSVSSANTCGIFSTASGKSVQVSDASLQNARQVFSEIEDSTK 2008
S ++SD S S SS ++ S S S SD+S + S+ DS+
Sbjct: 755 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSD 814
Query: 2009 QVFSKVLFKSNEHSDQLTREENTAIRTPEHLISQKGFSYNVVNSSAFSGFSTASGKQVSI 2068
S S+ + + + + + + + S G + N S S S +S S
Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSS 874
Query: 2069 LESSLHKVKGVLEEFDLIRTEHSLHYSPTSRQNVSKILPRVDKRNPEHCVNSEMEKTCSK 2128
S + D + S + S +S + S D N +S S+
Sbjct: 875 NSS---------DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSE 925
Query: 2129 EFKLSNNLNVEGGSSENNHS 2148
S+N N S+ ++ S
Sbjct: 926 SSNSSDNSNSSDSSNSSDSS 945
Score = 34.7 bits (78), Expect = 1.7
Identities = 64/320 (20%), Positives = 123/320 (38%), Gaps = 4/320 (1%)
Query: 1706 NTADYVGNYLYENNSNSTIAENDKNHLSEKQDTYLSNSSMSNSYSYHSDEVYNDSGYLSK 1765
N++D + +NSNS+ + N + S+ D+ S+ S ++S S +S + + + S
Sbjct: 919 NSSDSSESSNSSDNSNSSDSSNSSDS-SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977
Query: 1766 NKLDSGIEPVLKNVEDQKNTSFSKVISNVKDANAYPQTVNEDICVEELVTSSSPCKNKNA 1825
+ +S + D ++S S S+ D++ + N +S+S + ++
Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037
Query: 1826 AIKLSISNSNNFEVGPPAFRIASGKIVCVSHETIKKVKDIFTDSFSKVIKENNENKSKIC 1885
S +S++ + + S S + +DS ++ N S
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097
Query: 1886 QTKIMAGCYEALD--DSEDILHNSLDNDECSTHSHKVFADIQSEEILQHNQNMSGLEKVS 1943
+ + ++ D DS D +S +D + +D + + S S
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSS 1157
Query: 1944 KISPCDVSLETSDICKCSIGKLHKSVSSANTCGIFSTASGKSVQVSDASLQNARQVFSEI 2003
S S ++SD S + S SS ++ S+ S S SD+S + S+
Sbjct: 1158 DSSDSSDSSDSSDSSDSS-DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1216
Query: 2004 EDSTKQVFSKVLFKSNEHSD 2023
DS+ S SNE SD
Sbjct: 1217 SDSSDSSDSSDSSDSNESSD 1236
Score = 33.9 bits (76), Expect = 2.8
Identities = 65/313 (20%), Positives = 115/313 (36%), Gaps = 15/313 (4%)
Query: 1718 NNSNSTIAENDKNHLSEKQDTYLSNSSMSNSYSYHSDEVYNDSGYL--SKNKLDSGIEPV 1775
++S+S+ + N + SNSS S+ S SD +DS S + +S
Sbjct: 866 DSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSE 925
Query: 1776 LKNVEDQKNTSFSKVISNVKDANAYPQTVNEDICVEELVTSSSPCKNKNAAIKLSISNSN 1835
N D N+S S S+ D++ + + + +S S N + S +SN
Sbjct: 926 SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD----SSDSSN 981
Query: 1836 NFEVGPPAFRIASGKIVCVSHETIKKVKDIFTDSFSKVIKENNENKSKICQTKIMAGCYE 1895
+ + + S S+ + +DS + N+ + S + + +
Sbjct: 982 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041
Query: 1896 ALD-----DSEDILHNSLDNDECSTHSHKVFADIQSEEILQHNQNMSGLEKVSKISPCDV 1950
+ D DS D ++S +D + +D + + S S S
Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101
Query: 1951 SLETSDICKCSIGKLHKSVSSANTCGIFSTASGKSVQVSDASLQNARQVFSEIEDSTKQV 2010
S ++SD S S SS ++ S+ S S SD+S + SE DS+
Sbjct: 1102 SSDSSD----SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSS 1157
Query: 2011 FSKVLFKSNEHSD 2023
S S++ SD
Sbjct: 1158 DSSDSSDSSDSSD 1170
Score = 32.7 bits (73), Expect = 6.3
Identities = 85/441 (19%), Positives = 156/441 (35%), Gaps = 30/441 (6%)
Query: 1706 NTADYVGNYLYENNSNSTIAENDKNHLSEKQDTYLSNSSMSNSYSYHSDEVYNDSGYLSK 1765
+ +D +Y +++ S + +D N E +NS N+ S D YN S
Sbjct: 445 SNSDGYDSYDFDDKS---MQGDDPNSSDESNGNDDANSESDNNSSSRGDASYN-----SD 496
Query: 1766 NKLDSGIEPVLKNVEDQKNTSFSKVISNVKDANAYPQTVNEDICVEELVTSSSPCKNKNA 1825
D+G K ED + S S +N D+N N+D + S + ++
Sbjct: 497 ESKDNGNGSDSKGAEDDDSDSTSD--TNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDS 554
Query: 1826 AIKLSISNSNNFEVGPPAFRIASGKIVCVSHETIKKVKDIFTDSFSKVIKENNENKSKIC 1885
+ + S+S++ + +S ++ +DS + ++ + S
Sbjct: 555 SDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSN---SSDSSDSSDSS 611
Query: 1886 QTKIMAGCYEALDDSEDILHNSLDNDECSTHSHKVFADIQSEEILQHNQNMSGLEKVSKI 1945
+ + ++ DS +S D+D S S +D + N S S
Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDS 671
Query: 1946 SPCDVSLETSDICKCSIGKLHKSVSSANTCGIFSTASGKSVQVSDASLQNARQVFSEIED 2005
S S +SD S SS ++ S+ S +S SD+S ++ S+ D
Sbjct: 672 SDSSDSSSSSD----------SSNSSDSSDSSDSSNSSESSDSSDSSDSDS----SDSSD 717
Query: 2006 STKQVFSKVLFKSNEHSDQLTREENTAIRTPEHLISQKGFSYNVVNSSAFSGFSTASGKQ 2065
S+ S ++ S + +++ + S S + NSS S S +S
Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777
Query: 2066 VSILESSLHKVKGVLEEFDLIRTEHSLHYSPTSRQNVSKILPRVDKRNPEHCVNSEMEKT 2125
S S + + D + S + S +S + S D N NS
Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS---DSDSSNSSDSSNSSDSSD 834
Query: 2126 CSKEFKLSNNLNVEGGSSENN 2146
S S++ + GS ++
Sbjct: 835 SSNSSDSSDSSDSSDGSDSDS 855
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 40.8 bits (94), Expect = 0.023
Identities = 124/644 (19%), Positives = 252/644 (39%), Gaps = 97/644 (15%)
Query: 575 KNAGLISTLKKKTNKFIYAIHDETSYKGKKIPKDQKSELINCSAQFEANAFEAPLTFANA 634
KN L T+K+ I + Y G+ ++ ++N + E + E A
Sbjct: 952 KNEDLQKTIKQNEETLTQTI---SQYNGRLSVLTAENAMLNSKLENEKQSKER----LEA 1004
Query: 635 DSGLLHSSVKRSCSQND-SEEPTLSLTSSFGTILRKCSR---------NETCSNNTVISQ 684
+ HS + + D SE L +F +CSR + NN ++SQ
Sbjct: 1005 EVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQ 1064
Query: 685 DLDYKEAKCNKEKLQLFITPEADSLSCLQEGQCENDPKSKKVSDIKEEVLAAACHPVQHS 744
L E+K N +++ T +A L+E K+ + +++++ C ++
Sbjct: 1065 QLFKTESKLNSLEIEFHHTRDA-----LRE-------KTLGLERVQKDLSQTQCQ-MKEM 1111
Query: 745 KVEYSDTDFQSQKSLLYDHENASTLILTPTSKDVLSNLVMISRGKESYKMSDKLKGNNYE 804
+ +Y + + K + L + +L + + K K +K N +
Sbjct: 1112 EQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNK--EKTVINIQD 1169
Query: 805 SDVELTKNIPMEKNQDVCALNENYKNVELLPPEKYMRVASPSRKVQF-NQNTNLRVI--Q 861
+ + + E + L E +N EL+ +++ R+ Q+ N+ V+ Q
Sbjct: 1170 QFHAIVQKLQAESEKQSLLLEE--RNKELISECNHLK----ERQYQYENEKAEREVVVRQ 1223
Query: 862 KNQEETTSISKITVNPDSEELFSDNENNFVFQVANERNNLA-----LGNTKELHETDLTC 916
QE ++ K +++ S E+ S N + + + L L ++ H + C
Sbjct: 1224 LQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRC 1283
Query: 917 VNEPIFKNSTMVLYGD------TGDKQATQV-SIKKDLVYV-LAEENKN------SVKQH 962
+ ++ L D T KQ ++ ++K+L+ L+E+ K +KQ
Sbjct: 1284 AEK--MQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQS 1341
Query: 963 IKMTLGQDLKSDISL--------NIDKIPEKN-NDYMNKWAGLLGPISNHSFGGSFRTAS 1013
++ L Q++K ++ L N+ K+ K N+Y N SF G +T+
Sbjct: 1342 LECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN---------GEFSFHGDLKTSQ 1392
Query: 1014 NKEIKLSEHNIKKSKMFFKDIEEQYPTSLACVEIVNTLALDNQKKLSKPQSINTVSAHLQ 1073
+ + I K K D+ + T+ + ++T Q++L +++ LQ
Sbjct: 1393 FE----MDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQKKCEKLQ 1448
Query: 1074 SSVVVSDCK----NSHITPQMLFSKQDFNSNHNLTPSQKAEIT----ELSTILE-ESGSQ 1124
+ + + SHI M+ Q + + EI E++ L+ ++ SQ
Sbjct: 1449 KNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNLFLQAQAASQ 1508
Query: 1125 FEFTQFRKPSYILQKSTFEVP----ENQMTILKTTSEECRDADL 1164
QFR+ ++ KS E+ E++++ +KT+ E+ +L
Sbjct: 1509 ENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTEL 1552
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 40.0 bits (92), Expect = 0.040
Identities = 132/687 (19%), Positives = 265/687 (38%), Gaps = 71/687 (10%)
Query: 1013 SNKEIKLSEHNIKKSKMFFKDIEEQYPTSLACVEIVNTLALDNQK-KLSKPQSINTVSAH 1071
++K +K+ + N + SK + +E + ++ L+ D K K ++I T+ +
Sbjct: 490 ASKILKMEKENQRLSKKV-EILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN 548
Query: 1072 LQSSVVVSDCKNSHI--TPQMLFSKQDFNSNHNLTPSQKAEITELSTILEESGS----QF 1125
+ + + + +N H+ T L + ++ + +K +I E S +F
Sbjct: 549 SERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEF 608
Query: 1126 EFTQFRKP--SYILQKSTFEVPENQMTILKTTSEECRDADLHVIMNAPSIGQVDS-SKQF 1182
E Q +K Y + E EN++ L+ +E + ++ + I ++ + +
Sbjct: 609 EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL 668
Query: 1183 EGTVEIKRKFAGLLKN-----DCNKSASGYLTDENEVGFRGFYSAHGTKLNVSTEALQKA 1237
E +K KN + + + L +EN R S + ++ L+
Sbjct: 669 ERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLEN- 727
Query: 1238 VKLFSDIENISEETSAEVHPISLSSSKCHDSVVSM--FKIENHN-DKTVSEKNNKCQLIL 1294
++E+ E+ + + S K VS IEN KT+ N K Q +
Sbjct: 728 ----KELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLE 783
Query: 1295 QN--NIEMTTGTF---VEEITENYKRNTENEDNKYTAASRNSHNLEFDGSDSSKNDTVCI 1349
++EM T +EE+ + KR E + + + + + LE D K +
Sbjct: 784 SELQDLEMENQTLQKNLEELKISSKR-LEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842
Query: 1350 HKDETDLLFTDQHNICLKLSGQFMKEGNTQIKEDLSDLTFLEVAKAQEACHGNTSNKEQL 1409
+ E +++N+ + G KE T KE + +E+C KE
Sbjct: 843 QQAEIKDTTLEENNVKI---GNLEKENKTLSKE---------IGIYKESC---VRLKE-- 885
Query: 1410 TATKTEQNIKDFETSDTFFQTASGKNISVAKESFNKIVNFFDQKPEELHNFSLNSE--LH 1467
K + + T D +++ K ++ N ++ EL LN E LH
Sbjct: 886 -LEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLH 944
Query: 1468 SDIRKNKMDILSYEETDIVKHKILKESVPVGTGNQL-VTFQGQPERDEKIKEPTLLGFHT 1526
+ + TD ++K+L+ + L + + + +++E T ++
Sbjct: 945 DE-----------QSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEEST--NYNQ 991
Query: 1527 ASGKKVKIAKESLDKVKNLFDEKE--QGTSEITSFSHQWAKTLKY--REACKDLELACET 1582
+++K K++ + +K DE+ Q + I+ ++W + + RE K + E
Sbjct: 992 QLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIE- 1050
Query: 1583 IEITAAPKCKEMQNSLNNDKNLVSIETVVPPKLLSDNLCRQTENLKTSKSIFLKVKVHEN 1642
+E A E Q K L + + ++L+ L RQT +L+ +
Sbjct: 1051 VERNNATLQAEKQALKTQLKQLETQNNNLQAQILA--LQRQTVSLQEQNTTLQTQNAKLQ 1108
Query: 1643 VEKETAKSPATCYTNQSPYSVIENSAL 1669
VE T S +T NQ+ +I+ S+L
Sbjct: 1109 VENSTLNSQSTSLMNQNAQLLIQQSSL 1135
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 39.7 bits (91), Expect = 0.052
Identities = 113/582 (19%), Positives = 224/582 (38%), Gaps = 78/582 (13%)
Query: 338 ADECEKSKNQVKEKYSFVSEVEPNDTD---PLDSNVA----NQKPFESGSDKISKEVVPS 390
++ KS NQ +F ++ D PL S + +++ E G K + S
Sbjct: 21 SESSRKSWNQKHFALTFPKPLQRGTNDKSRPLKSQITVTRHDKRKLEEGQKPAHKWIRHS 80
Query: 391 LA--CEWSQLTLSGLNGAQMEKIPLLHISSCDQNISEKDLLDTENKR-----KKDFLTSE 443
+W + A E+ P H+ + ++ + + +++++ KKD S+
Sbjct: 81 FRKILQWPPIYT-----AAREQTPFRHLYTSKTHLKKAEYKKSKDEKGGTPLKKD---SK 132
Query: 444 NSLPRISSLPKSEKPLNEETV-VNKRDEEQHLESHTDCILAVKQAISGTSPVASSFQGIK 502
++ P+S++ + E+T N+ D+ SH + ++ S T+P + + + +
Sbjct: 133 KKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVS 192
Query: 503 KSIF-RIRESPKETFNASFSGHMTDPNFKKETEASESGLE-IHTVCSQKE---DSLC--- 554
K+ + ++ K + + T N KK+ + S++ + I +CS+ D L
Sbjct: 193 KNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVG 252
Query: 555 ---PNLIDNGSWPATTTQNSVALKNAGLISTLKKKTNKFIYAIHDETSYKGKKIPKDQKS 611
I+ +W +QN+ + KK T K D S K KD K
Sbjct: 253 QSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKK 312
Query: 612 ELINCSAQFEANAFEAPLTFANADSGLLHSSVK------RSCSQNDSEEPTLSLTSSFGT 665
N + + +A+SG K + ++D ++ T S T
Sbjct: 313 VKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDT 372
Query: 666 I-------------LRKCSRNETCSNN-------TVISQDLDYKEAKCNKEKLQLFI--- 702
L+K S+N+ + T +L+ KE++ +++K +
Sbjct: 373 ESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTD 432
Query: 703 ----------TPEADSLSCLQEGQCENDPKSKKVSDIKEEVLAAACHPVQHSKVEYSDTD 752
+ +ADS + + D K K K++ A + +++E SD +
Sbjct: 433 NKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEME-SDLE 491
Query: 753 FQSQKSLLYDHENASTLILTPTSKDVLSNLVMISRG-KESYKMSDKLKGNNYESDVELTK 811
+ K + + + I KD S K +K S K+KG++ ES+ L K
Sbjct: 492 LKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYK 551
Query: 812 NIPMEKNQDVCALNENYKNVELLPPEKYMRVASPSRKVQFNQ 853
+K + + N K +E L ++ R++ S+K FN+
Sbjct: 552 PGAKKKIDESDGTSANSK-MEGLESKRGFRMS--SKKTTFNE 590
Score = 36.2 bits (82), Expect = 0.57
Identities = 78/362 (21%), Positives = 140/362 (38%), Gaps = 49/362 (13%)
Query: 649 QNDSEEPTLSLTSSFGTILRKCSRNET---CSNNTVISQDL---DYKEAKCNKEKLQLFI 702
QN++++ L + + S +ET N+ +S++ D K++K +K+ F+
Sbjct: 155 QNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFL 214
Query: 703 TPEADSLSCLQEGQCENDPKSKKVSDIKEEVLAAACHPVQHSKVEYSDTDFQSQKSLLYD 762
+ + L+ + NDP S+ S+ V V S E + D + +
Sbjct: 215 HTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLML--VGQSDDESINFDAWLRNYSQNN 272
Query: 763 HENASTLILTPTSKDVLSNLVMISRG-----KESYKMSDKLKGN--------NYESDVEL 809
+N S T KD N S K++ K S K+K N + + D E
Sbjct: 273 SKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTES 332
Query: 810 T-------KNIPMEKNQDVCALNENYKNVELLPPEKYMRVASPSRKVQFNQNTNLRVIQK 862
T K+ + +D L ++ K + + S K N + NL+ K
Sbjct: 333 TDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASK 392
Query: 863 NQEETTSISKITVNPDSEELFSDNENNFVFQVANERNNLALGNTKELHETDLTCVNEPIF 922
N ++ KIT + DSE E+ +E+ + K+ +TD N+
Sbjct: 393 NDDKKKDAKKITFSTDSESELESKESQ-----KDEKKD------KKDSKTD----NKKSV 437
Query: 923 KNSTMVLYGDT---GDKQATQVSIKKDLVYVLAEENKNSVKQHIKMTLGQDLKSDISLNI 979
KN D+ GD + + KK ++ K K++ + T +++SD+ L
Sbjct: 438 KNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAEST---EMESDLELKK 494
Query: 980 DK 981
DK
Sbjct: 495 DK 496
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 39.3 bits (90), Expect = 0.068
Identities = 94/470 (20%), Positives = 180/470 (38%), Gaps = 53/470 (11%)
Query: 1210 DENEVGFRGFYSAHGTKLNVSTEALQKAVKLFSDIENISEETSAEVHPISLSSSKCHDSV 1269
D+ E G+ G +LN +T ++A++ SD++ I E+ ++ K V
Sbjct: 1428 DQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREV 1487
Query: 1270 VSMFKIENHNDKTVSEKNNKCQ-----------LILQNNIEMTTGTFV---EEITENYKR 1315
+ + +K + N++ I Q + F E++ +N K
Sbjct: 1488 DRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKA 1547
Query: 1316 NTENEDNKYTAASRNSHNLEFDGSDSSKNDTVCIHKDETDLLFTDQHNICLKLSGQFMKE 1375
EN D R + LE N+ + K + + L T Q+N + + E
Sbjct: 1548 EKENNDK----IQRLNEELE------KSNECAEMLKQKVEEL-TRQNNETKLMMQRIQAE 1596
Query: 1376 GNTQIKEDLSDLTFLEVAKAQEACHGNTSNKEQLTATKTEQNIKDFETSDTFFQTASGKN 1435
+ E + E K Q K+QL +T E K +T F +
Sbjct: 1597 SENIVLEKQTIQQRCEALKIQA-----DGFKDQLRST-NEHLHKQTKTEQDFQRKIKCLE 1650
Query: 1436 ISVAKESFNKIVNFFDQKPEELHNFSLNSELHSDIRKNKMDI-LSYEETDIVKHKI-LKE 1493
+AK +V+ F QK ++ + N++ ++R ++ S EE + K+ L++
Sbjct: 1651 EDLAKS--QNLVSEFKQKCDQQNIIIQNTK--KEVRNLNAELNASKEEKRRGEQKVQLQQ 1706
Query: 1494 SVPVGTGNQLVTFQGQ---PERDEKIKEPTLLGFHTASGKKVKIAKESLDKVKNLFDEKE 1550
+ N+L Q + +E++ ++ F SGK + A+E K++ L + K
Sbjct: 1707 AQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKV 1766
Query: 1551 QGTSEITSFSHQWAKTLKYREACKDLELACET----IEITAAPKCKEMQNSLNNDKNLVS 1606
++I+ + + ++ CET +E ++MQ + + N
Sbjct: 1767 ITENDISGIRLDFVSLQQENSRAQENAKLCETNIKELERQLQQYREQMQQGQHMEANHYQ 1826
Query: 1607 IETVVPPKLLSDNLCRQTENLKTSKSIFLKVKVHENV-------EKETAK 1649
+ +L++ R+ ENLK +K H+ V +K TAK
Sbjct: 1827 KCQKLEDELIAQK--REVENLKQKMDQQIKEHEHQLVLLQCEIQKKSTAK 1874
>gi|30089940 Golgi autoantigen, golgin subfamily a, 3 [Homo sapiens]
Length = 1498
Score = 39.3 bits (90), Expect = 0.068
Identities = 36/154 (23%), Positives = 70/154 (45%), Gaps = 7/154 (4%)
Query: 2841 FRNEREEEKEAAKYVEAQQKRLEALFTKIQEEFEE-HEENTTKPYLPSR-----ALTRQQ 2894
+R + + + ++A +KRL++ ++++E + H E T SR A RQ
Sbjct: 855 YRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQH 914
Query: 2895 VRALQDGAELYEAVKNAADPAYLEGYFSEEQLRALNNHRQMLNDKKQAQIQLEIRKAMES 2954
+ L+ + + ++ + F +EQ+ A+ + L K+ ++Q E RKA+
Sbjct: 915 MADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALK-KQIEELQQEARKAITE 973
Query: 2955 AEQKEQGLSRDVTTVWKLRIVSYSKKEKDSVILS 2988
+QK + L D+T+ K + E ILS
Sbjct: 974 QKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILS 1007
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 39.3 bits (90), Expect = 0.068
Identities = 73/322 (22%), Positives = 141/322 (43%), Gaps = 47/322 (14%)
Query: 677 SNNTVISQDLDYKEAKCNKEKLQLFITPEA---DSLSC------LQEGQCENDPKSKKVS 727
+ N ++S+ L E+K N ++QL T +A +SL L + QC+ +++++
Sbjct: 963 AKNEILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQK-KETEQMY 1021
Query: 728 DIKEEVLAAACHPVQHSKVEYSDTDFQSQKSLLYD-----HENASTLILTPTSKDVLSNL 782
I++ L + + VE + QS+ LL H+ A++ T ++ +
Sbjct: 1022 QIEQSKLKK--YIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHS 1079
Query: 783 VMISRGKESYKMSDKLKGNNYESDVELTKNIPMEKNQDVCALNENYKNVELLP-----PE 837
+ ES K L+ N E E +++ D C + + ++L P
Sbjct: 1080 AAKNLQAESEKQILSLQEKNKELMDEYNH---LKERMDQCEKEKAGRKIDLTEAQETVPS 1136
Query: 838 KYMRVASPSRKVQFNQNT-NLRVIQKNQEETTSISKITVNPDSEELFSDNENNFVFQVAN 896
+ + + + + +Q Q +++ IQK Q ET +K + + L S E N + +
Sbjct: 1137 RCLHLDAENEVLQLQQTLFSMKAIQK-QCETLQKNKKQLKQEVVNLKSYMERNMLERGKA 1195
Query: 897 ERNNLALGN--TKELHETDLTCVNEPIFKNSTMVLYGDTGDKQATQVSIKKDLVYVLAEE 954
E + L + KE+ E +NE I T KQA ++ + + L E+
Sbjct: 1196 EWHKLLIEERARKEIEEK----LNEAIL----------TLQKQA---AVSHEQLVQLRED 1238
Query: 955 NKNSVKQHIKMTLGQDLKSDIS 976
N S+K +++T+ +DL+S+IS
Sbjct: 1239 NTTSIKTQMELTI-KDLESEIS 1259
>gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]
Length = 1816
Score = 38.5 bits (88), Expect = 0.12
Identities = 84/418 (20%), Positives = 161/418 (38%), Gaps = 54/418 (12%)
Query: 485 KQAISGTSPVASSFQGIKKSIFRIRESPKETFNASFSGHMTDPNFKKETEASESGLEIHT 544
KQ++ G++ IKK + E +T N FS ++ N ++ +S +
Sbjct: 1048 KQSLPGSN---CKHPEIKKQEY---EEVVQTVNTDFSPYLISDNLEQPMGSSHAS----Q 1097
Query: 545 VCSQKEDSLCPNLIDNGSWPATTTQNSVALKNAGLISTLKKKTNKFIYA----IHDETSY 600
VCS+ D +L+D+G T+ +K + + + + + + H +
Sbjct: 1098 VCSETPD----DLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ 1153
Query: 601 KGKKIPKDQKSELINCSAQFEANAFEAPLTFANADS----GLLHSSVKRSCSQNDSEEPT 656
++ K +S N S++ E L F ++ HS+V C ++EE
Sbjct: 1154 GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL 1213
Query: 657 LSLTSSFGTILRKCSRNETCSNNTVISQDLDYKEAKCNKEKLQLFITPEADSLSCLQEGQ 716
LSL +S CSN ++ AK ++E ++ E + L Q
Sbjct: 1214 LSLKNSL----------NDCSNQVIL--------AKASQEH---HLSEETKCSASLFSSQ 1252
Query: 717 CENDPKSKKVSDIKEEVLAAACHPVQHSKVEYSDTDFQSQKSLLYDHENASTLILTPTSK 776
C ++ ++ L + ++H S S K L+ D E T + +
Sbjct: 1253 CSELEDLTANTNTQDPFLIGSSKQMRHQ--SESQGVGLSDKELVSDDEERGTGLEENNQE 1310
Query: 777 D--VLSNLVMISRGKES-YKMSDKLKGNNYESDVELT-KNIPMEKN-----QDVCALNEN 827
+ + SNL + G ES +S+ G + +SD+ T + M+ N Q++ L
Sbjct: 1311 EQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAV 1370
Query: 828 YKNVELLPPEKYMRVASPSRKVQFNQNTNLRVIQKNQEETTSISKITVNPDSEELFSD 885
+ P Y + S S ++ +N +K + S+ ++ + E L +D
Sbjct: 1371 LEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSAD 1428
Score = 35.4 bits (80), Expect = 0.98
Identities = 40/158 (25%), Positives = 68/158 (43%), Gaps = 14/158 (8%)
Query: 1054 DNQKKLSKPQSINTVSAHLQSSVVVS-DCKNSHITPQMLFSKQDFNSNHNLTPSQKAEIT 1112
+NQ++ S ++ ++ +S VS DC +L ++Q HNL Q+ E+
Sbjct: 1307 NNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQ-EMA 1365
Query: 1113 ELSTILEESGSQFEFTQFRKPSYILQKSTFEVPEN--QMTILKTTSEECRDADLHVIMNA 1170
EL +LE+ GSQ PS I S E N Q T K + ++ + N
Sbjct: 1366 ELEAVLEQHGSQ---PSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNP 1422
Query: 1171 PSIGQVDSSKQFEGTVE---IKRKFAGLLKNDCNKSAS 1205
+ S+ +FE + + K K G+ ++ +K S
Sbjct: 1423 EGL----SADKFEVSADSSTSKNKEPGVERSSPSKCPS 1456
>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
Length = 1863
Score = 38.5 bits (88), Expect = 0.12
Identities = 84/418 (20%), Positives = 161/418 (38%), Gaps = 54/418 (12%)
Query: 485 KQAISGTSPVASSFQGIKKSIFRIRESPKETFNASFSGHMTDPNFKKETEASESGLEIHT 544
KQ++ G++ IKK + E +T N FS ++ N ++ +S +
Sbjct: 1095 KQSLPGSN---CKHPEIKKQEY---EEVVQTVNTDFSPYLISDNLEQPMGSSHAS----Q 1144
Query: 545 VCSQKEDSLCPNLIDNGSWPATTTQNSVALKNAGLISTLKKKTNKFIYA----IHDETSY 600
VCS+ D +L+D+G T+ +K + + + + + + H +
Sbjct: 1145 VCSETPD----DLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ 1200
Query: 601 KGKKIPKDQKSELINCSAQFEANAFEAPLTFANADS----GLLHSSVKRSCSQNDSEEPT 656
++ K +S N S++ E L F ++ HS+V C ++EE
Sbjct: 1201 GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL 1260
Query: 657 LSLTSSFGTILRKCSRNETCSNNTVISQDLDYKEAKCNKEKLQLFITPEADSLSCLQEGQ 716
LSL +S CSN ++ AK ++E ++ E + L Q
Sbjct: 1261 LSLKNSL----------NDCSNQVIL--------AKASQEH---HLSEETKCSASLFSSQ 1299
Query: 717 CENDPKSKKVSDIKEEVLAAACHPVQHSKVEYSDTDFQSQKSLLYDHENASTLILTPTSK 776
C ++ ++ L + ++H S S K L+ D E T + +
Sbjct: 1300 CSELEDLTANTNTQDPFLIGSSKQMRHQ--SESQGVGLSDKELVSDDEERGTGLEENNQE 1357
Query: 777 D--VLSNLVMISRGKES-YKMSDKLKGNNYESDVELT-KNIPMEKN-----QDVCALNEN 827
+ + SNL + G ES +S+ G + +SD+ T + M+ N Q++ L
Sbjct: 1358 EQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAV 1417
Query: 828 YKNVELLPPEKYMRVASPSRKVQFNQNTNLRVIQKNQEETTSISKITVNPDSEELFSD 885
+ P Y + S S ++ +N +K + S+ ++ + E L +D
Sbjct: 1418 LEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSAD 1475
Score = 35.4 bits (80), Expect = 0.98
Identities = 40/158 (25%), Positives = 68/158 (43%), Gaps = 14/158 (8%)
Query: 1054 DNQKKLSKPQSINTVSAHLQSSVVVS-DCKNSHITPQMLFSKQDFNSNHNLTPSQKAEIT 1112
+NQ++ S ++ ++ +S VS DC +L ++Q HNL Q+ E+
Sbjct: 1354 NNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQ-EMA 1412
Query: 1113 ELSTILEESGSQFEFTQFRKPSYILQKSTFEVPEN--QMTILKTTSEECRDADLHVIMNA 1170
EL +LE+ GSQ PS I S E N Q T K + ++ + N
Sbjct: 1413 ELEAVLEQHGSQ---PSNSYPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNP 1469
Query: 1171 PSIGQVDSSKQFEGTVE---IKRKFAGLLKNDCNKSAS 1205
+ S+ +FE + + K K G+ ++ +K S
Sbjct: 1470 EGL----SADKFEVSADSSTSKNKEPGVERSSPSKCPS 1503
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 38.1 bits (87), Expect = 0.15
Identities = 43/185 (23%), Positives = 81/185 (43%), Gaps = 25/185 (13%)
Query: 2860 KRLEALFTKIQEEFEEHEENTTKPYLPSRALTRQQVRALQ---------DGAELYEAVKN 2910
+ L+A ++QE+FE + + K R L+ +++ AL+ A+ K
Sbjct: 1114 RELQAQIAELQEDFESEKASRNKAEKQKRDLS-EELEALKTELEDTLDTTAAQQELRTKR 1172
Query: 2911 AADPAYLEGYFSEEQLRALNNHRQMLNDKKQ--AQIQLEIRKAMESA-------EQKEQG 2961
+ A L+ EE NH + D +Q A E+ + +E A E+ +QG
Sbjct: 1173 EQEVAELKKALEEE----TKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQG 1228
Query: 2962 LSRD-VTTVWKLRIVSYSKKEKDSVILSIWRPSSDLYSLLTEGKRYRIYHLATSKSKSKS 3020
L D +++++ K E + + +L++ ++EG R R+ LA SK ++
Sbjct: 1229 LETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRV-ELAEKASKLQN 1287
Query: 3021 ERANI 3025
E N+
Sbjct: 1288 ELDNV 1292
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 38.1 bits (87), Expect = 0.15
Identities = 252/1367 (18%), Positives = 503/1367 (36%), Gaps = 279/1367 (20%)
Query: 862 KNQEETTSISKITVNPDSEEL-FSDNENNFVFQVANERNNLALGNTKELHETDLTC---- 916
K + E K ++ + EEL S + N ++V + ELH+ L
Sbjct: 421 KMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKE 480
Query: 917 --VNEPIFKNSTMVLYGDTGDKQATQVSIKKDLVYVLAEENKNSVKQHIKMTLGQDLKSD 974
+N+ I + T++ + D+Q + + K ++ + +++ S +Q+ ++ LK D
Sbjct: 481 QELNQSISEKETLIAEIEELDRQNQEAT--KHMILI---KDQLSKQQNEGDSIISKLKQD 535
Query: 975 ISLNIDKIPEKNNDYMNKWAGLLGPISNHSFGGSFRTASNKEIKLSEHNIKKSKMFFKDI 1034
++ ++ + +D M+ KE+ + + + +S++ D+
Sbjct: 536 LNDEKKRVHQLEDDKMD---------------------ITKELDVQKEKLIQSEVALNDL 574
Query: 1035 EEQYPTSLACVEIVNTLALDNQKKLSKPQSINTVSAHLQSSVVVSDCKNSHITPQMLFS- 1093
+ T + V L K SI + L+ + ++ + S I +++ S
Sbjct: 575 ---HLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSL 631
Query: 1094 KQDFNSNHN--LTPSQKAEITELSTILEESGSQFEFTQFRKPSYILQKSTFEVP-ENQMT 1150
QD NSN L ++AE+ L L E + + L+K F+V EN+
Sbjct: 632 NQDSNSNFKDTLLKEREAEVRNLKQNLSE---------LEQLNENLKKVAFDVKMENEKL 682
Query: 1151 ILKTTS-----EECRDADLHVIMNAPSIGQVDSSKQFEGTVEIKRKFAGLLKNDCNKSAS 1205
+L EEC + + + +I V++ K +G +E + +A K + A+
Sbjct: 683 VLACEDVRHQLEECLAGNNQLSLEKNTI--VETLKMEKGEIEAELCWA---KKRLLEEAN 737
Query: 1206 GYLTDENEVGFRGFYSAHGTKLNVSTEALQ----KAVKLFSDIENISEETSAEVHPISLS 1261
Y E+ N++T ALQ +KL + E + +
Sbjct: 738 KYEKTIEELS---------NARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTD 788
Query: 1262 SSKCHDSVVSMFKIENHNDKTVSEKNNKCQLILQNNIEMTTGTFVEEITENYKRNTENED 1321
+ D + S ++ E+ QLI + I F+E++ E + E D
Sbjct: 789 HKETKDVLSS----------SLEEQKQLTQLINKKEI------FIEKLKERSSKLQEELD 832
Query: 1322 NKYTAASRNSHNLEFDGSDSSKNDTVCIHKDETDLLFTDQHNICLKLSGQFMKEGNTQIK 1381
KY+ A R KN+ + +E D MKE N ++
Sbjct: 833 -KYSQALR-------------KNEILRQTIEEKDRSLGS------------MKEENNHLQ 866
Query: 1382 EDLSDLTFLEVAKAQEACHGNTSNKEQLTATKTEQNIKDFETSDTFFQTASG-KNISVAK 1440
E+L L +E+ + T + D +T D+ + AS ++ K
Sbjct: 867 EELERL------------------REEQSRTAP---VADPKTLDSVTELASEVSQLNTIK 905
Query: 1441 ESFNKIVNFFDQKPEELHNFSLNSELHSDIRKNKMDILSYEETDIVKHKILKESVPVGTG 1500
E + + + E+ + + +K +MD Y+ + T
Sbjct: 906 EHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMN-----------ATH 954
Query: 1501 NQLVTFQGQPERDEKIKEPTLLGFHTASGKKVKIAKESLDKVKNLFDEKEQG--TSEITS 1558
QL E+DE+IK +++++++K E+ Q T
Sbjct: 955 TQLFL-----EKDEEIKS----------------LQKTIEQIKTQLHEERQDIQTDNSDI 993
Query: 1559 FSHQWAKTLKYREACKDLELA-CETIEITAAPKCKEMQNSLNNDKNLVSIETVVPPKLLS 1617
F ++L + +L+ ET + K +E++ L N+KN+ + + +L
Sbjct: 994 FQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQI--DQLSK 1051
Query: 1618 DNLCRQTENLKTSKSIFLKVKVHENVEKETAKSPATCYTNQS--PYSVIENSALAFYTSC 1675
D + + T+ ++ L+++ T+ + Y Q Y++ A
Sbjct: 1052 DEVGKLTQIIQQKD---LEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEK 1108
Query: 1676 SRKTSVSQTS------LLEAKKWLREGIFDGQPERINTADYVGNYLYEN---NSNSTIAE 1726
+R+ S +T ++ AK+ + D + + G ++ N + I E
Sbjct: 1109 TRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLSTRFESSGQDMFRETIQNLSRIIRE 1168
Query: 1727 NDK--NHLSEKQDTYLSNSSMSNSYSYHSDEVYNDSGYLSKNKLDS------GIEPVLKN 1778
D + LS+K T L+ S++ N++G ++ N+ + ++ +K
Sbjct: 1169 KDIEIDALSQKCQTLLAVLQTSSTG--------NEAGGVNSNQFEELLQERDKLKQQVKK 1220
Query: 1779 VEDQKNTSFSKVISNVKDANAYPQTVNEDICVEELVTSSSPCKNKNAAIKLSISNSNNFE 1838
+E+ K + V N++ +A Q + + LV S + K + L S N
Sbjct: 1221 MEEWKQQVMTTV-QNMQHESAQLQEELHQLQAQVLVDSDNNSKLQVDYTGLIQSYEQN-- 1277
Query: 1839 VGPPAFRIASGKIVCVSHETIKKVKDIFTDSFSKVIKENNENKSKICQTKIMAGCYEALD 1898
ET K +F + + + + ++C TK
Sbjct: 1278 ------------------ETKLK-------NFGQELAQVQHSIGQLCNTK---------- 1302
Query: 1899 DSEDILHNSLDNDECSTHSHKVFADIQSEEILQHNQNMSGLEKVSKISPCDVSLETSDIC 1958
D+L LD S + QS E L + S +V E+S++
Sbjct: 1303 ---DLLLGKLDIISPQLSSASLLTP-QSAECL-------------RASKSEVLSESSELL 1345
Query: 1959 KCSIGKLHKSVSSANTCGIFSTASGKSVQVSDASLQNARQVFSEIEDSTKQVFSKVLFKS 2018
+ + +L KS+ + A+ +++Q ++ L ++ SE+E + + +
Sbjct: 1346 QQELEELRKSLQEKD-------ATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQL 1398
Query: 2019 NEHSD---QLTREENTAIR--TPEHLISQKGFSYNVVNSSAFSGFSTASGKQVSILESSL 2073
E D +L +E++ I+ + + L S + F+ V + T +++ ILE +
Sbjct: 1399 KEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERILILEMDI 1458
Query: 2074 HKVKGVLEEFDLIRTEHSLHYSPTSRQNVSKILPRVDKRNPEHCVNSEMEKTCSKEFKLS 2133
K+KG E+ Y N+ + +K H S EK + E L
Sbjct: 1459 GKLKGENEKIVETYRGKETEYQALQETNMKFSMMLREKEFECH---SMKEKALAFEQLLK 1515
Query: 2134 NNLNVEGGSSENNHSIKVSPYLSQ----FQQDKQQLVLGTKVSLVEN 2176
+G + E N + + + FQQ++ Q++L K +EN
Sbjct: 1516 EK--EQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMEN 1560
>gi|62821787 COBL-like 1 [Homo sapiens]
Length = 1166
Score = 38.1 bits (87), Expect = 0.15
Identities = 49/236 (20%), Positives = 89/236 (37%), Gaps = 38/236 (16%)
Query: 745 KVEYSDTDFQSQKSLLYDHENASTLI--------LTPTSKDVLSNLVMISRGKES----- 791
K E TD Q S++YD N ++ L P ++V + +++ E
Sbjct: 517 KQETKSTDGQEPHSVVYDTSNGKKVVDSIRNLKSLGPNQENVQNEIIVYPENTEDNMKNG 576
Query: 792 -----YKMSDKLKGNNYESDVELTKNIPMEKNQDVCALNENYKNVELLPPEKYMRVASPS 846
+ K NN + +VE N + + EN+ +P +K + ++
Sbjct: 577 VKKTEINVEGVAKNNNIDMEVERPSNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEK 636
Query: 847 RK---VQFNQNTNLRVIQKNQEETTSISKITVNPDSEELFSDNENNFVFQVANERNNLAL 903
K +Q + N K+Q+ S SK+ EE + NN Q + + ++
Sbjct: 637 TKDAAIQTTPSCN-SFDGKHQDHNLSDSKV------EECVQTSNNNISTQHSCLSSQDSV 689
Query: 904 GNTKE--------LHETDLTCVNEPI--FKNSTMVLYGDTGDKQATQVSIKKDLVY 949
++E +H D V +PI N ++ D DK +T +K +Y
Sbjct: 690 NTSREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLY 745
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 37.4 bits (85), Expect = 0.26
Identities = 130/685 (18%), Positives = 264/685 (38%), Gaps = 68/685 (9%)
Query: 1013 SNKEIKLSEHNIKKSKMFFKDIEEQYPTSLACVEIVNTLALDNQK-KLSKPQSINTVSAH 1071
++K +K+ + N + SK + +E + ++ L+ D K K ++I T+ +
Sbjct: 490 ASKILKMEKENQRLSKKV-EILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN 548
Query: 1072 LQSSVVVSDCKNSHI--TPQMLFSKQDFNSNHNLTPSQKAEITELSTILEESGS----QF 1125
+ + + + +N H+ T L + ++ + +K +I E S +F
Sbjct: 549 SERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEF 608
Query: 1126 EFTQFRKP--SYILQKSTFEVPENQMTILKTTSEECRDADLHVIMNAPSIGQVDS-SKQF 1182
E Q +K Y + E EN++ L+ +E + ++ + I ++ + +
Sbjct: 609 EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL 668
Query: 1183 EGTVEIKRKFAGLLKN-----DCNKSASGYLTDENEVGFRGFYSAHGTKLNVSTEALQKA 1237
E +K KN + + + L +EN R S + ++ L+
Sbjct: 669 ERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLEN- 727
Query: 1238 VKLFSDIENISEETSAEVHPISLSSSKCHDSVVSM--FKIENHN-DKTVSEKNNKCQLIL 1294
++E+ E+ + + S K VS IEN KT+ N K Q +
Sbjct: 728 ----KELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLE 783
Query: 1295 QN--NIEMTTGTF---VEEITENYKRNTENEDNKYTAASRNSHNLEFDGSDSSKNDTVCI 1349
++EM T +EE+ + KR E + + + + + LE D K +
Sbjct: 784 SELQDLEMENQTLQKNLEELKISSKR-LEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842
Query: 1350 HKDETDLLFTDQHNICLKLSGQFMKEGNTQIKEDLSDLTFLEVAKAQEACHGNTSNKEQL 1409
+ E +++N+ + G KE T KE + +E+C KE
Sbjct: 843 QQAEIKDTTLEENNVKI---GNLEKENKTLSKE---------IGIYKESC---VRLKE-- 885
Query: 1410 TATKTEQNIKDFETSDTFFQTASGKNISVAKESFNKIVNFFDQKPEELHNFSLNSELHSD 1469
K + + T D +++ K ++ N ++ EL LN E
Sbjct: 886 -LEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKER--- 941
Query: 1470 IRKNKMDILSYEETDIVKHKILKESVPVGTGNQL-VTFQGQPERDEKIKEPTLLGFHTAS 1528
+L E++ ++K+L+ + L + + + +++E T ++
Sbjct: 942 -------LLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEEST--NYNQQL 992
Query: 1529 GKKVKIAKESLDKVKNLFDEKE--QGTSEITSFSHQWAKTLKY--REACKDLELACETIE 1584
+++K K++ + +K DE+ Q + I+ ++W + + RE K + E +E
Sbjct: 993 RQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIE-VE 1051
Query: 1585 ITAAPKCKEMQNSLNNDKNLVSIETVVPPKLLSDNLCRQTENLKTSKSIFLKVKVHENVE 1644
A E Q K L + + ++L+ L RQT +L+ + VE
Sbjct: 1052 RNNATLQAEKQALKTQLKQLETQNNNLQAQILA--LQRQTVSLQEQNTTLQTQNAKLQVE 1109
Query: 1645 KETAKSPATCYTNQSPYSVIENSAL 1669
T S +T NQ+ +I+ S+L
Sbjct: 1110 NSTLNSQSTSLMNQNAQLLIQQSSL 1134
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 37.4 bits (85), Expect = 0.26
Identities = 115/568 (20%), Positives = 222/568 (39%), Gaps = 78/568 (13%)
Query: 1051 LALDNQKKLSKPQS--INTVSAHLQSSVVVSDCKNSHITPQMLFSKQDFNSNHNLTPSQK 1108
L ++N+ K K + +N H Q + +S+ KN ++ ++ Q SN+++
Sbjct: 852 LTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEV----QQIQSNYDIA---- 903
Query: 1109 AEITELSTILEESGSQFEFTQFRKPSYILQKSTFEVPEN--QMTILKTTSEECRDAD-LH 1165
I EL +++S +Q + + K S ++ +T + N Q+ ++ T +E R D +
Sbjct: 904 --IAELH--VQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVS 959
Query: 1166 VIMNAPSIGQVDSSKQFEGTVEIKRKFAGLLKNDCNKSASGYLTDENEVGFRGFYSAHGT 1225
I N + D S E + LL ND YL + +R
Sbjct: 960 QISNIDLLNLRDLSNGSEED-NLPNTQLDLLGND-------YLVSKQVKEYRIQEPNREN 1011
Query: 1226 KLNVSTEALQKAVKLFSDIENISEETSAEVHPISLSSSKCHDSVVSMFKIENHNDKTVSE 1285
+ S EA+ + K +I S + S ++ + K V +K EN+ K
Sbjct: 1012 SFHSSIEAIWEECK---EIVKASSKKSHQIEELEQQIEKLQAEVKG-YKDENNRLKEKEH 1067
Query: 1286 KNNKCQLILQNNIEMTTGTFVEEITENYKRNTENEDNKYTAASRNSHNLEFDGSDSSKND 1345
KN Q+++ T ++++ E E ++ T + H +E + S
Sbjct: 1068 KN-------QDDLLKEKETLIQQLKE------ELQEKNVTLDVQIQHVVEGKRALSELTQ 1114
Query: 1346 TVCIHKDETDLLFTDQHNICLKLSGQFMKEGNTQIKEDLSDLTFLEVAKAQEACHGNTSN 1405
V +K + L T ++ S E + KE + + + QE + N
Sbjct: 1115 GVTCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKN 1174
Query: 1406 KEQLTATKTEQNIKDFETSDTFFQTASG----KNISVAKESFNKIVNFFDQK-PEELHNF 1460
+ L N+K+ + + Q + K++ KE + +K EEL
Sbjct: 1175 TKDL-------NVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSAS 1227
Query: 1461 SLNSE-LHSDIRKNKMDILSYEE--TDIVKH-KILKESVPVGTGNQLVTFQGQPERDEKI 1516
S ++ L +D+++ + D +E TD K K +++ V V + D+ +
Sbjct: 1228 SARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSV-----------MRDEDKLL 1276
Query: 1517 KEPTLLGFHTASGKKVKIAKESLDKVKNLFDEKEQGTSEITSFSHQWAKTLKYREACKDL 1576
+ + + KK + ++E K + + KEQ ++ + Q +Y ACKDL
Sbjct: 1277 R----IKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQ-----QYERACKDL 1327
Query: 1577 ELACETIEITAAPKCKEMQNSLNNDKNL 1604
+ + IE ++ Q + D+ L
Sbjct: 1328 NVKEKIIEDMRMTLEEQEQTQVEQDQVL 1355
>gi|130980075 centromere protein J [Homo sapiens]
Length = 1338
Score = 37.0 bits (84), Expect = 0.34
Identities = 45/246 (18%), Positives = 98/246 (39%), Gaps = 13/246 (5%)
Query: 2840 IFRNEREEEKEAAKYVEAQQKRLE--ALFTKIQEEFEEHEENTTKPYLPSRALTRQQVRA 2897
I E E EK A+ + R+E + K+++E + E+ K ++++R
Sbjct: 910 IIELETEIEKFKAENASLAKLRIERESALEKLRKEIADFEQQKAKELARIEEFKKEEMRK 969
Query: 2898 LQDGAELYEAVKNAAD--PAYLEGYFSEEQLRALNNHRQMLNDK--KQAQIQLEIRKAME 2953
LQ +++E AA P E + + + + R+ L K K + +R ++
Sbjct: 970 LQKERKVFEKYTTAARTFPDKKEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQ 1029
Query: 2954 SAEQKEQGLSRDVTTVWKLRIVSYSKKEKDSVILSIWRPSSDLYSLLTEGKRYRIYHLAT 3013
++ L ++ + + R+ ++ + E L + + L R++ +++
Sbjct: 1030 MLVRENTDLREEIKVMERFRLDAWKRAEAIESSLEVEKKDK----LANTSVRFQNSQISS 1085
Query: 3014 SKSKSKSERANIQLAATKKTQYQQLPVSDEILF---QIYQPREPLHFSKFLDPDFQPSCS 3070
K ++ + + + + P D Q PREPL F DP+++
Sbjct: 1086 GTQVEKYKKNYLPMQGNPPRRSKSAPPRDLGNLDKGQAASPREPLEPLNFPDPEYKEEEE 1145
Query: 3071 EVDLIG 3076
+ D+ G
Sbjct: 1146 DQDIQG 1151
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 37.0 bits (84), Expect = 0.34
Identities = 77/353 (21%), Positives = 143/353 (40%), Gaps = 40/353 (11%)
Query: 1274 KIENHNDKTVSEKNNKCQLILQNNIEMTTGTFVEEITENYKRNTENEDNKYTAASRNSHN 1333
K+++ K S+KN+K IL+ I + ++E +R + E +R +
Sbjct: 68 KVKSSESKKESQKNDKDLKILEKEIRV----LLQERGAQDRRIQDLETELEKMEARLNAA 123
Query: 1334 LEFDGSDSSKNDTVCIHKDETDLLFTDQHNICLKLSGQFMKEGNTQIKEDLSDLTFLEVA 1393
L S S+ N T+ E L+ + N LK +F + GN + LS L +++
Sbjct: 124 LREKTSLSANNATL-----EKQLIELTRTNELLK--SKFSENGNQKNLRILS-LELMKLR 175
Query: 1394 KAQEACHGNTSNKEQLTATKTEQNIKDFETSDTFFQTASGKNISVAKESFNKIVNFFDQK 1453
+E K++ K + + E S GK +S+ KE ++ +
Sbjct: 176 NKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDE-----KSE 230
Query: 1454 PEELHNFSLNSELHSD-IRKNKMDILSYEETDIVKHKILKESVPVGTGNQLVTFQGQPER 1512
E+L + SD + K K+DI EE LKE +++++ + E
Sbjct: 231 TEKLLEYIEEISCASDQVEKYKLDIAQLEEN-------LKEK-----NDEILSLKQSLEE 278
Query: 1513 DEKIKEPTLLGFHTASGKKVKIAKESLDKVKNLFDEKEQGTSEITSFSHQWAKTLKYREA 1572
+ I + + K + KE D V + E +E+ + ++ + RE
Sbjct: 279 NIVILSKQVEDLNV---KCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREK 335
Query: 1573 CKDLELACETIEITAAPKCKEMQNSLNNDKNLVSI-ETVVPPKLLSDNLCRQT 1624
+ EL +++ + KE+ +SL+ + L S E +V K L + +QT
Sbjct: 336 LQQKELQIDSL----LQQEKELSSSLH--QKLCSFQEEMVKEKNLFEEELKQT 382
>gi|22749197 motile sperm domain containing 2 [Homo sapiens]
Length = 518
Score = 37.0 bits (84), Expect = 0.34
Identities = 31/134 (23%), Positives = 62/134 (46%), Gaps = 12/134 (8%)
Query: 1251 TSAEVHPISLSSSKCHDSVVSMFKIENHNDKTVSEKNNKCQLILQNNIEMTTGTFVEEIT 1310
T+ E + + S+S C + H TVS ++ LI+ +E ++GT E+T
Sbjct: 367 TAPEKYRVKPSNSSCDPGASVDIVVSPHGGLTVSAQDRF--LIMAAEMEQSSGTGPAELT 424
Query: 1311 ENYKRNTENEDNKYTAASRNSHNLEFDGSDSSKNDTVCIHKDETDLLFTDQHNICLKLSG 1370
+ +K N+ + H L +SSK +T+ + + ++ +ICL+LS
Sbjct: 425 QFWKEVPRNKVME--------HRLRCHTVESSKPNTLTLKDNAFNMSDKTSEDICLQLSR 476
Query: 1371 QFMKEGNTQIKEDL 1384
+ E N ++++ +
Sbjct: 477 --LLESNRKLEDQV 488
>gi|42415492 chromosome 14 open reading frame 106 [Homo sapiens]
Length = 1132
Score = 36.6 bits (83), Expect = 0.44
Identities = 59/306 (19%), Positives = 123/306 (40%), Gaps = 34/306 (11%)
Query: 826 ENYKNVELLPPEKYMRVASPSRKVQFNQNTNLRVIQKNQEETTSISKITVN--PDSEELF 883
++ N EL+ ++Y S+K++ + TN R+I+ ++ETT ++++ E+ F
Sbjct: 577 DDLSNQELIGKKEYKM---SSKKLKIGERTNERIIKSQKQETTEELDVSIDILTSREQFF 633
Query: 884 SDNENNFVFQVANERNNLALGNTKELHETDLTCVNEPIFKNSTMVLYGDTGDKQATQVSI 943
SD E ++ + ++ + + K + C+ + + +I
Sbjct: 634 SDEERKYM-AINQKKAYILVTPLKSRKVIEQRCMRYNL-----------------SAGTI 675
Query: 944 KKDLVYVLAEENKNSVKQHIKMTLGQDLKSDISLNIDKIPEKNNDYMNKWAGLLGPISNH 1003
K +V+ E K S TL + S N + E++ +N+ +
Sbjct: 676 KAVTDFVIPECQKKSPISKSMGTLENTFEGHKSKNKEDCDERDLLTVNRKIKISNLEKEQ 735
Query: 1004 SFGGSFRTASNKEIKLSEHNIKKSKMFFKDIEEQYPTSLACVEIVNTLALDNQKKLSKPQ 1063
F+ + KL + + + F+K Q L+ E + + ++ K +
Sbjct: 736 MLTSDFKKNTRLLPKLKKIENQVAMSFYK---HQSSPDLSSEESETEKEIKRKAEVKKTK 792
Query: 1064 SINTVSA--HLQSSVVVSDCKNSHITPQMLFSKQDFNSNHNLTPSQKAEITELSTILEES 1121
+ NT A HL+ S +N+ P +L + + + N +KA + T L++S
Sbjct: 793 AGNTKEAVVHLRKST-----RNTSNIPVILEPETEESENEFYIKQKKARPSVKET-LQKS 846
Query: 1122 GSQFEF 1127
G + EF
Sbjct: 847 GVRKEF 852
>gi|133778961 testis expressed 15 [Homo sapiens]
Length = 2789
Score = 36.6 bits (83), Expect = 0.44
Identities = 97/473 (20%), Positives = 176/473 (37%), Gaps = 63/473 (13%)
Query: 172 KGRQTPKHISESLGAEVDPDMSWSSSLATPPTLSSTVL--IVRNEEASETVFPHDTTANV 229
K T H+ E E P+ S + T S V N SE P
Sbjct: 1115 KSHPTTSHMGEFCNQE-HPESQLPVSSTSQSTSQSVYYNSSVSNPSLSEEHQPFSGKTAY 1173
Query: 230 KSYFSNHDESLKKNDRFIASVTDSENTNQREAASHGFGKTSGNSFKVNSCK-DHIGKSMP 288
+ DE L + + I + S + + H ++ K NSC + +
Sbjct: 1174 LFSPDHSDEKLIEKENQIDTAFLSSTSKYEKLEKHSANHNVKDATKENSCDANEVINESN 1233
Query: 289 NVLEDEVYETVVDTSEEDSFSLCF--SKCRTKNLQKVRTSKTR---KKIFHEANADECEK 343
+V + E + ++ D + C +K +T L V S + ++ + N +
Sbjct: 1234 SVSLSCIKENINSSTGNDCDATCIGHTKAKTDVLISVLDSNVKHFLNDLYQQGNLILSDC 1293
Query: 344 SKNQVKEKYSFVSEVEPNDTDPLDSNVANQKPFESGSDKISKEVVPSLACEWSQLTLSGL 403
+N +E TDP++ N ++ ++ S QL+ + +
Sbjct: 1294 KRN-----------LEVKWTDPIERPKQNIITGNFLMGPLNLTLIASKKYSIPQLSAAAV 1342
Query: 404 NGAQ-------MEKIPLLHISS---------CDQNISEKDLLDTENKRKKDFLTSENSLP 447
++ ++K +L + S C+Q+ EK+LL TE + L ++ +
Sbjct: 1343 TDSEGESSKSYLDKQRILTVDSFAASSTVPHCEQSCREKELLKTEQCSSGNCLHTDGNET 1402
Query: 448 RISSLPKSEKPLNEETVVNKRDEEQHLE-SHTDCILAVKQAISGTSPVASSFQGIKKSI- 505
++ E + T +K E +E S +D L +K + G+S S +KK
Sbjct: 1403 NVTE--NYELDVASGTEEDKSYGENIVELSSSDSSLLLKDNVKGSS---SETCIVKKDTE 1457
Query: 506 ----FRIRESPKETFNASFSGHMTDPNFKKETEASESGLEIHTVCSQKEDSLCPNLIDNG 561
++++++ K ++ + MT+ + TE +I E + NLID+
Sbjct: 1458 DRITWKVKQAEKAK-DSVYKRSMTEGS-TVNTEYKNQKNQISEESCLNEKIITTNLIDSH 1515
Query: 562 SWPATTTQNSVALKNAGLISTLKKKTNKFIYAIHDETSYKGK-KIPKDQKSEL 613
TT SV LKN T+ NK KG+ K+ KD +S+L
Sbjct: 1516 LSTKNTTTESVPLKN-----TVSNPLNK--------REKKGEIKVSKDSQSDL 1555
Score = 32.7 bits (73), Expect = 6.3
Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 6/67 (8%)
Query: 414 LHISSCDQNISEKDLLDTENKRKKDFLTSENSLPRISSLPK------SEKPLNEETVVNK 467
LHISS DQNI KDL + +K LTS++S SSL + S+ + ++V+N
Sbjct: 921 LHISSRDQNIPHKDLRRHKIYGRKRRLTSQDSSECFSSLSQGRIKTFSQSEKHIKSVLNI 980
Query: 468 RDEEQHL 474
+E L
Sbjct: 981 LSDEASL 987
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 127,730,590
Number of Sequences: 37866
Number of extensions: 5877185
Number of successful extensions: 15211
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 148
Number of HSP's that attempted gapping in prelim test: 14733
Number of HSP's gapped (non-prelim): 642
length of query: 3418
length of database: 18,247,518
effective HSP length: 121
effective length of query: 3297
effective length of database: 13,665,732
effective search space: 45055918404
effective search space used: 45055918404
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.