Guide to the Human Genome
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Name: GAA Sequence: fasta or formatted (952aa) NCBI GI: 119393893
Description:

acid alpha-glucosidase preproprotein

Referenced in:

Hexokinases and Initial Sugar Metabolism
Lysosomes and Related Organelles

Other entries for this name:
alt mRNA [952aa] acid alpha-glucosidase preproprotein
alt mRNA [952aa] acid alpha-glucosidase preproprotein
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.7         73           2
 C cysteine            1.6         15           2
 D aspartate           4.2         40           2
 E glutamate           5.3         50           2
 F phenylalanine       4.6         44           2
 G glycine             7.7         73           2
 H histidine           3.2         30           1
 I isoleucine          3.0         29           2
 K lysine              1.6         15           1
 L leucine            11.3        108           2
 M methionine          2.1         20           2
 N asparagine          3.3         31           2
 P proline             8.5         81           4
 Q glutamine           4.7         45           2
 R arginine            5.3         50           2
 S serine              6.9         66           3
 T threonine           6.6         63           3
 V valine              7.0         67           2
 W tryptophan          2.2         21           2
 Y tyrosine            3.3         31           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   acid alpha-glucosidase preproprotein 
GAA                   1.000   acid alpha-glucosidase preproprotein 
GAA                   1.000   acid alpha-glucosidase preproprotein 
MGAM                  0.358   maltase-glucoamylase 
SI                    0.354   sucrase-isomaltase 
LOC642103             0.308   PREDICTED: similar to sucrase-isomaltase 
GANC                  0.158   glucosidase, alpha; neutral C 
GANAB                 0.156   neutral alpha-glucosidase AB isoform 3 
GANAB                 0.156   neutral alpha-glucosidase AB isoform 2 
KIAA1161              0.029   hypothetical protein LOC57462 
TFF2                  0.008   trefoil factor 2 precursor 
TFF3                  0.007   trefoil factor 3 precursor 
TFF1                  0.007   trefoil factor 1 precursor 
DDX11                 0.006   DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 iso...
LOXL1                 0.005   lysyl oxidase-like 1 preproprotein 
CRIM1                 0.004   cysteine-rich motor neuron 1 
LOC123855             0.004   PREDICTED: similar to hCG2042536 
LOC123855             0.004   PREDICTED: similar to hCG2042536 
C19orf61              0.004   hypothetical protein LOC56006 
ZP4                   0.004   zona pellucida glycoprotein 4 preproprotein 
FAM186A               0.003   family with sequence similarity 186, member A [Homo...
SMARCA2               0.003   SWI/SNF-related matrix-associated actin-dependent re...
SMARCA2               0.003   SWI/SNF-related matrix-associated actin-dependent re...
CHPF2                 0.003   chondroitin polymerizing factor 2 
HOXD4                 0.003   homeobox D4 
LOC100293375          0.003   PREDICTED: hypothetical protein 
LOC100288697          0.003   PREDICTED: hypothetical protein 
LOC100288697          0.003   PREDICTED: hypothetical protein XP_002342494 
FBLN2                 0.003   fibulin 2 isoform b precursor 
FBLN2                 0.003   fibulin 2 isoform a precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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