Guide to the Human Genome
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Search of human proteins with 239756689

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens]
         (1941 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens]           3922   0.0  
gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]           3922   0.0  
gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens]           3922   0.0  
gi|149944548 neurobeachin-like 2 [Homo sapiens]                       107   1e-22
gi|148233596 LPS-responsive vesicle trafficking, beach and ancho...   105   4e-22
gi|31543297 neutral sphingomyelinase (N-SMase) activation associ...   104   7e-22
gi|221625547 neutral sphingomyelinase (N-SMase) activation assoc...   104   7e-22
gi|62422577 neurobeachin [Homo sapiens]                               103   1e-21
gi|224451124 neurobeachin-like 1 isoform 3 [Homo sapiens]             102   4e-21
gi|149944613 neurobeachin-like 1 isoform 1 [Homo sapiens]             102   4e-21
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho...   100   1e-20
gi|154240744 neurobeachin-like 1 isoform 2 [Homo sapiens]              96   3e-19
gi|191252801 WDFY family member 4 [Homo sapiens]                       90   2e-17
gi|54292123 lysosomal trafficking regulator [Homo sapiens]             69   4e-11
gi|89886480 zinedin isoform 2 [Homo sapiens]                           62   4e-09
gi|89886477 zinedin isoform 1 [Homo sapiens]                           62   4e-09
gi|26665869 WD repeat domain 51B [Homo sapiens]                        61   1e-08
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]             59   5e-08
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]             59   5e-08
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]             59   5e-08
gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens]              56   4e-07
gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens]              56   4e-07
gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens]              56   4e-07
gi|21071067 TBP-associated factor 5 [Homo sapiens]                     52   6e-06
gi|38569484 kinesin family member 21A [Homo sapiens]                   51   1e-05
gi|83779014 katanin p80 subunit B 1 [Homo sapiens]                     49   4e-05
gi|16554629 WD repeat domain 5 [Homo sapiens]                          49   6e-05
gi|16554627 WD repeat domain 5 [Homo sapiens]                          49   6e-05
gi|166795264 AE binding protein 2 isoform b [Homo sapiens]             49   6e-05
gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]            49   6e-05

>gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens]
          Length = 1941

 Score = 3922 bits (10170), Expect = 0.0
 Identities = 1941/1941 (100%), Positives = 1941/1941 (100%)

Query: 1    MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60
            MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA
Sbjct: 1    MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60

Query: 61   RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120
            RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG
Sbjct: 61   RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120

Query: 121  GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180
            GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA
Sbjct: 121  GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180

Query: 181  LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240
            LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF
Sbjct: 181  LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240

Query: 241  SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300
            SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR
Sbjct: 241  SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300

Query: 301  LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360
            LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF
Sbjct: 301  LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360

Query: 361  HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420
            HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT
Sbjct: 361  HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420

Query: 421  RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480
            RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM
Sbjct: 421  RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480

Query: 481  ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540
            ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD
Sbjct: 481  ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540

Query: 541  LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600
            LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP
Sbjct: 541  LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600

Query: 601  EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660
            EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE
Sbjct: 601  EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660

Query: 661  QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720
            QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL
Sbjct: 661  QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720

Query: 721  LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780
            LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE
Sbjct: 721  LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780

Query: 781  MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840
            MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG
Sbjct: 781  MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840

Query: 841  KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900
            KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE
Sbjct: 841  KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900

Query: 901  LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960
            LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK
Sbjct: 901  LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960

Query: 961  YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020
            YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE
Sbjct: 961  YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020

Query: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080
            ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP
Sbjct: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080

Query: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140
            ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG
Sbjct: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140

Query: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200
            DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG
Sbjct: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200

Query: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260
            DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP
Sbjct: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260

Query: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320
            TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS
Sbjct: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320

Query: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380
            YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL
Sbjct: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380

Query: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440
            TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ
Sbjct: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440

Query: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500
            QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII
Sbjct: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500

Query: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560
            RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG
Sbjct: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560

Query: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620
            SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY
Sbjct: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620

Query: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680
            WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY
Sbjct: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680

Query: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740
            GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV
Sbjct: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740

Query: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800
            PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS
Sbjct: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800

Query: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
            VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK
Sbjct: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860

Query: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920
            PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA
Sbjct: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920

Query: 1921 LLPTKRHLLLGSDNGVIRLLA 1941
            LLPTKRHLLLGSDNGVIRLLA
Sbjct: 1921 LLPTKRHLLLGSDNGVIRLLA 1941


>gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]
          Length = 2240

 Score = 3922 bits (10170), Expect = 0.0
 Identities = 1941/1941 (100%), Positives = 1941/1941 (100%)

Query: 1    MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60
            MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA
Sbjct: 300  MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 359

Query: 61   RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120
            RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG
Sbjct: 360  RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 419

Query: 121  GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180
            GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA
Sbjct: 420  GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 479

Query: 181  LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240
            LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF
Sbjct: 480  LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 539

Query: 241  SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300
            SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR
Sbjct: 540  SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 599

Query: 301  LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360
            LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF
Sbjct: 600  LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 659

Query: 361  HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420
            HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT
Sbjct: 660  HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 719

Query: 421  RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480
            RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM
Sbjct: 720  RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 779

Query: 481  ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540
            ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD
Sbjct: 780  ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 839

Query: 541  LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600
            LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP
Sbjct: 840  LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 899

Query: 601  EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660
            EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE
Sbjct: 900  EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 959

Query: 661  QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720
            QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL
Sbjct: 960  QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 1019

Query: 721  LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780
            LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE
Sbjct: 1020 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 1079

Query: 781  MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840
            MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG
Sbjct: 1080 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 1139

Query: 841  KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900
            KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE
Sbjct: 1140 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 1199

Query: 901  LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960
            LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK
Sbjct: 1200 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 1259

Query: 961  YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020
            YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE
Sbjct: 1260 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1319

Query: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080
            ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP
Sbjct: 1320 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1379

Query: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140
            ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG
Sbjct: 1380 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1439

Query: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200
            DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG
Sbjct: 1440 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1499

Query: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260
            DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP
Sbjct: 1500 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1559

Query: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320
            TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS
Sbjct: 1560 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1619

Query: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380
            YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL
Sbjct: 1620 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1679

Query: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440
            TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ
Sbjct: 1680 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1739

Query: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500
            QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII
Sbjct: 1740 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1799

Query: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560
            RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG
Sbjct: 1800 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1859

Query: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620
            SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY
Sbjct: 1860 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1919

Query: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680
            WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY
Sbjct: 1920 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1979

Query: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740
            GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV
Sbjct: 1980 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 2039

Query: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800
            PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS
Sbjct: 2040 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 2099

Query: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
            VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK
Sbjct: 2100 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 2159

Query: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920
            PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA
Sbjct: 2160 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 2219

Query: 1921 LLPTKRHLLLGSDNGVIRLLA 1941
            LLPTKRHLLLGSDNGVIRLLA
Sbjct: 2220 LLPTKRHLLLGSDNGVIRLLA 2240


>gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens]
          Length = 1941

 Score = 3922 bits (10170), Expect = 0.0
 Identities = 1941/1941 (100%), Positives = 1941/1941 (100%)

Query: 1    MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60
            MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA
Sbjct: 1    MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60

Query: 61   RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120
            RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG
Sbjct: 61   RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120

Query: 121  GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180
            GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA
Sbjct: 121  GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180

Query: 181  LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240
            LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF
Sbjct: 181  LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240

Query: 241  SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300
            SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR
Sbjct: 241  SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300

Query: 301  LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360
            LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF
Sbjct: 301  LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360

Query: 361  HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420
            HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT
Sbjct: 361  HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420

Query: 421  RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480
            RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM
Sbjct: 421  RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480

Query: 481  ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540
            ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD
Sbjct: 481  ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540

Query: 541  LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600
            LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP
Sbjct: 541  LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600

Query: 601  EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660
            EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE
Sbjct: 601  EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660

Query: 661  QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720
            QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL
Sbjct: 661  QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720

Query: 721  LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780
            LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE
Sbjct: 721  LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780

Query: 781  MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840
            MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG
Sbjct: 781  MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840

Query: 841  KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900
            KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE
Sbjct: 841  KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900

Query: 901  LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960
            LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK
Sbjct: 901  LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960

Query: 961  YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020
            YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE
Sbjct: 961  YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020

Query: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080
            ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP
Sbjct: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080

Query: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140
            ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG
Sbjct: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140

Query: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200
            DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG
Sbjct: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200

Query: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260
            DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP
Sbjct: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260

Query: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320
            TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS
Sbjct: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320

Query: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380
            YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL
Sbjct: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380

Query: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440
            TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ
Sbjct: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440

Query: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500
            QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII
Sbjct: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500

Query: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560
            RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG
Sbjct: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560

Query: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620
            SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY
Sbjct: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620

Query: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680
            WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY
Sbjct: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680

Query: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740
            GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV
Sbjct: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740

Query: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800
            PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS
Sbjct: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800

Query: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
            VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK
Sbjct: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860

Query: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920
            PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA
Sbjct: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920

Query: 1921 LLPTKRHLLLGSDNGVIRLLA 1941
            LLPTKRHLLLGSDNGVIRLLA
Sbjct: 1921 LLPTKRHLLLGSDNGVIRLLA 1941


>gi|149944548 neurobeachin-like 2 [Homo sapiens]
          Length = 2754

 Score =  107 bits (267), Expect = 1e-22
 Identities = 97/310 (31%), Positives = 131/310 (42%), Gaps = 68/310 (21%)

Query: 342  QEELRS--LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH----- 393
            QE LR+  L   WV   ISNF YLMQLN +AGR   D + +PV PWV+ D+ +P      
Sbjct: 2056 QEMLRASGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPTLDLSN 2115

Query: 394  -GRFRDLRKSKFRLNKGDKQLDFTYEMTRQAFVA--GGAGGGEPPHVPHHISDVLSDITY 450
               FRDL K    +N    QL       R+ + +    AG  +  H   H S+    + Y
Sbjct: 2116 PAVFRDLSKPIGVVNPKHAQL------VREKYESFEDPAGTIDKFHYGTHYSNAAGVMHY 2169

Query: 451  YVYKARRTPRSVL-------CGH-----VRAQWEPH-EYPASMERMQNWTPDECIPEFYT 497
             +     T   V        C       V A W+   E PA ++        E IPEF+ 
Sbjct: 2170 LIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQARLESPADVK--------ELIPEFFY 2221

Query: 498  DPSIFRS-----------IHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWID 546
             P    +            +  + D+ +P W SS ++F+  HR  LES  VS  LH WID
Sbjct: 2222 FPDFLENQNGFDLGCLQLTNEKVGDVVLPPWASSPEDFIQQHRQALESEYVSAHLHEWID 2281

Query: 547  LTFGYKLQGKEAVKEKNVCL-----------HLVDAHTHLASYGVV--------QLFDQP 587
            L FGYK +G  A +  NV             H+ D     A  G++        QL  +P
Sbjct: 2282 LIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVTDERERKALEGIISNFGQTPCQLLKEP 2341

Query: 588  HPQRLAGAPA 597
            HP RL+   A
Sbjct: 2342 HPTRLSAEEA 2351



 Score = 32.7 bits (73), Expect = 3.5
 Identities = 57/236 (24%), Positives = 84/236 (35%), Gaps = 38/236 (16%)

Query: 1580 GPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAYWQYEIGVSQQDAHFHFHQI 1639
            GP  P SGV G  L    D   L           SG    +W   + V+         Q+
Sbjct: 2452 GPWVPGSGVSGQALAVAPDGKLL----------FSGG---HWDGSLRVTALPRGKLLSQL 2498

Query: 1640 RLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYT--QHR 1697
                   H   V C+A  +   + +SGS+D T  +W L + G  +   AP+ V     H 
Sbjct: 2499 SC-----HLDVVTCLALDTCGIYLISGSRDTTCMVWRLLHQGGLSVGLAPKPVQVLYGHG 2553

Query: 1698 KSVFFVGQLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755
             +V  V         VS   DG V +     G+ +  + PL         A  P P   +
Sbjct: 2554 AAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPLG--------ATFPGPIFHL 2605

Query: 1756 TMASSDS-TLRFVDCRKPGLQ-----HEFRLGGGLNPGLVRALAISPSGRSVVAGF 1805
             + S     ++     +PG Q     H + + G L   L   LA  P+  +V   F
Sbjct: 2606 ALGSEGQIVVQSSAWERPGAQVTYSLHLYSVNGKLRASL--PLAEQPTALTVTEDF 2659


>gi|148233596 LPS-responsive vesicle trafficking, beach and anchor
            containing [Homo sapiens]
          Length = 2863

 Score =  105 bits (262), Expect = 4e-22
 Identities = 93/287 (32%), Positives = 120/287 (41%), Gaps = 59/287 (20%)

Query: 352  WVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRDLRKSK 403
            W H  ISNF YLM LN +AGR   D N +PV PWV+        D T P   FRDL K  
Sbjct: 2215 WQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPTN-FRDLSKPI 2273

Query: 404  FRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPH-HISDVLSDITYYV-YKARRTPRS 461
              LN             R AF A      E   VP  H     S  ++ + +  R  P +
Sbjct: 2274 GALNP-----------KRAAFFAERYESWEDDQVPKFHYGTHYSTASFVLAWLLRIEPFT 2322

Query: 462  VLCGHVRAQWEPHEYPASMERMQNW------TPD--ECIPEFYTDPSIFRSIH------- 506
                +++     H         + W      T D  E IPEFY  P +F + +       
Sbjct: 2323 TYFLNLQGGKFDHADRTFSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVM 2382

Query: 507  ---PDMPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563
                 + D+++P W  +S+EFV  +R  LES  VS  LH WIDL FGYK QG EAV+  N
Sbjct: 2383 DDGTVVSDVELPPWAKTSEEFVHINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALN 2442

Query: 564  VCLHLV-----------------DAHTHLASYGVV--QLFDQPHPQR 591
            V  +L                       + S+G    QL  +PHP R
Sbjct: 2443 VFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPR 2489


>gi|31543297 neutral sphingomyelinase (N-SMase) activation
           associated factor isoform 1 [Homo sapiens]
          Length = 917

 Score =  104 bits (260), Expect = 7e-22
 Identities = 87/286 (30%), Positives = 127/286 (44%), Gaps = 49/286 (17%)

Query: 347 SLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRD 398
           S +L W  G +SN+ YL+ LN LA R   D + +PV PW++        D + P G FRD
Sbjct: 300 SYMLQWQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWIIHDYSSSELDLSNP-GTFRD 358

Query: 399 LRKSKFRLNKG--DKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKAR 456
           L K    LNK   ++ L    EM    F+ G +    P +V  ++  +  +    +   R
Sbjct: 359 LSKPVGALNKERLERLLTRYQEMPEPKFMYG-SHYSSPGYVLFYLVRIAPEYMLCLQNGR 417

Query: 457 RTPRSVLCGHVRAQWEPHEYPASMERMQNWTPDECIPEFYTDPSIF--RSIHPDM----- 509
                 +   +   W+     A+  +       E IPEFY D   F   S+  D+     
Sbjct: 418 FDNADRMFNSIAETWKNCLDGATDFK-------ELIPEFYGDDVSFLVNSLKLDLGKRQG 470

Query: 510 ----PDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKNVC 565
                D+++P W SS ++F+   +  LES  VS  LH WIDL FGYK +G +AV   NV 
Sbjct: 471 GQMVDDVELPPWASSPEDFLQKSKDALESNYVSEHLHEWIDLIFGYKQKGSDAVGAHNVF 530

Query: 566 LHL-----VDAH------------THLASYGVV--QLFDQPHPQRL 592
             L     VD +            T +  +G    QLF  PHP+R+
Sbjct: 531 HPLTYEGGVDLNSIQDPDEKVAMLTQILEFGQTPKQLFVTPHPRRI 576



 Score = 35.8 bits (81), Expect = 0.42
 Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 14/154 (9%)

Query: 1714 SCDGAVHVWDPFTGKTLRT-------VEPLDSRVPLTAVAVMPAPHTSITMASSDSTLRF 1766
            S D  V VW     +   T       +  L+  V +  ++ + A  T +   + + T+  
Sbjct: 731  SWDSTVKVWSGVPAEMPGTKRHHFDLLAELEHDVSVDTIS-LNAASTLLVSGTKEGTVNI 789

Query: 1767 VDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPA 1826
             D     L H+       + G+V   A SP  R V++  + G + ++D +TG+++    +
Sbjct: 790  WDLTTATLMHQIPC----HSGIVCDTAFSPDSRHVLSTGTDGCLNVIDVQTGMLISSMTS 845

Query: 1827 HEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
             E    +    +G+ ++S S    L VW  L  K
Sbjct: 846  DEPQ--RCFVWDGNSVLSGSQSGELLVWDLLGAK 877


>gi|221625547 neutral sphingomyelinase (N-SMase) activation
           associated factor isoform 2 [Homo sapiens]
          Length = 948

 Score =  104 bits (260), Expect = 7e-22
 Identities = 87/286 (30%), Positives = 127/286 (44%), Gaps = 49/286 (17%)

Query: 347 SLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRD 398
           S +L W  G +SN+ YL+ LN LA R   D + +PV PW++        D + P G FRD
Sbjct: 331 SYMLQWQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWIIHDYSSSELDLSNP-GTFRD 389

Query: 399 LRKSKFRLNKG--DKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKAR 456
           L K    LNK   ++ L    EM    F+ G +    P +V  ++  +  +    +   R
Sbjct: 390 LSKPVGALNKERLERLLTRYQEMPEPKFMYG-SHYSSPGYVLFYLVRIAPEYMLCLQNGR 448

Query: 457 RTPRSVLCGHVRAQWEPHEYPASMERMQNWTPDECIPEFYTDPSIF--RSIHPDM----- 509
                 +   +   W+     A+  +       E IPEFY D   F   S+  D+     
Sbjct: 449 FDNADRMFNSIAETWKNCLDGATDFK-------ELIPEFYGDDVSFLVNSLKLDLGKRQG 501

Query: 510 ----PDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKNVC 565
                D+++P W SS ++F+   +  LES  VS  LH WIDL FGYK +G +AV   NV 
Sbjct: 502 GQMVDDVELPPWASSPEDFLQKSKDALESNYVSEHLHEWIDLIFGYKQKGSDAVGAHNVF 561

Query: 566 LHL-----VDAH------------THLASYGVV--QLFDQPHPQRL 592
             L     VD +            T +  +G    QLF  PHP+R+
Sbjct: 562 HPLTYEGGVDLNSIQDPDEKVAMLTQILEFGQTPKQLFVTPHPRRI 607



 Score = 35.8 bits (81), Expect = 0.42
 Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 14/154 (9%)

Query: 1714 SCDGAVHVWDPFTGKTLRT-------VEPLDSRVPLTAVAVMPAPHTSITMASSDSTLRF 1766
            S D  V VW     +   T       +  L+  V +  ++ + A  T +   + + T+  
Sbjct: 762  SWDSTVKVWSGVPAEMPGTKRHHFDLLAELEHDVSVDTIS-LNAASTLLVSGTKEGTVNI 820

Query: 1767 VDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPA 1826
             D     L H+       + G+V   A SP  R V++  + G + ++D +TG+++    +
Sbjct: 821  WDLTTATLMHQIPC----HSGIVCDTAFSPDSRHVLSTGTDGCLNVIDVQTGMLISSMTS 876

Query: 1827 HEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
             E    +    +G+ ++S S    L VW  L  K
Sbjct: 877  DEPQ--RCFVWDGNSVLSGSQSGELLVWDLLGAK 908


>gi|62422577 neurobeachin [Homo sapiens]
          Length = 2946

 Score =  103 bits (258), Expect = 1e-21
 Identities = 96/299 (32%), Positives = 127/299 (42%), Gaps = 50/299 (16%)

Query: 352  WVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRDLRKSK 403
            W    ISNF YLM LN +AGR   D N +PV PWV+        D T P G FRDL K  
Sbjct: 2289 WQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLP-GNFRDLSKPI 2347

Query: 404  FRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVL 463
              LN   K+  F  E     +         P H   H S   S +++ V     T   + 
Sbjct: 2348 GALNP--KRAVFYAER----YETWEDDQSPPYHYNTHYSTATSTLSWLVRIEPFTTFFLN 2401

Query: 464  CGHVRAQWEPHEYPA---SMERMQNWTPD--ECIPEFYTDPSIF----------RSIHPD 508
                +       + +   S    Q  T D  E IPEFY  P +F          R     
Sbjct: 2402 ANDGKFDHPDRTFSSVARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNLGVREDEVV 2461

Query: 509  MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKNVCLHL 568
            + D+D+P W    ++FV  +R  LES  VS  LH WIDL FGYK +G EAV+  NV  +L
Sbjct: 2462 VNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYL 2521

Query: 569  -------VDAHT----------HLASYGVV--QLFDQPHPQRLAGAP-ALAPEPPLIPK 607
                   +D+ T           + ++G    QL  +PHP R +       P+ PL+ K
Sbjct: 2522 TYEGSVNLDSITDPVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFK 2580


>gi|224451124 neurobeachin-like 1 isoform 3 [Homo sapiens]
          Length = 2694

 Score =  102 bits (254), Expect = 4e-21
 Identities = 88/294 (29%), Positives = 127/294 (43%), Gaps = 48/294 (16%)

Query: 348  LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 400
            L   WV+  ISNF YL+Q+N +AGR   D   +PV PW++ D+T+          FRDL 
Sbjct: 2003 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 2062

Query: 401  KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 459
            K    +N K  K +   YE           G  +  H   H S+    + Y +     T 
Sbjct: 2063 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 2117

Query: 460  RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 508
              +     R   A  + H  PA+ + + +   D  E IPEF+  P    + +        
Sbjct: 2118 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 2177

Query: 509  -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563
                 + D+ +P W  S+++F+  HR  LES  VS  LH WIDL FGYK +G  AV+  N
Sbjct: 2178 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 2237

Query: 564  VCLH-----------LVDAHTHLASYGVV--------QLFDQPHPQRLAGAPAL 598
            V  +           L D     A  G++        QL  +PHP RL+   A+
Sbjct: 2238 VFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAV 2291


>gi|149944613 neurobeachin-like 1 isoform 1 [Homo sapiens]
          Length = 1404

 Score =  102 bits (254), Expect = 4e-21
 Identities = 88/294 (29%), Positives = 127/294 (43%), Gaps = 48/294 (16%)

Query: 348  LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 400
            L   WV+  ISNF YL+Q+N +AGR   D   +PV PW++ D+T+          FRDL 
Sbjct: 713  LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 772

Query: 401  KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 459
            K    +N K  K +   YE           G  +  H   H S+    + Y +     T 
Sbjct: 773  KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 827

Query: 460  RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 508
              +     R   A  + H  PA+ + + +   D  E IPEF+  P    + +        
Sbjct: 828  LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 887

Query: 509  -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563
                 + D+ +P W  S+++F+  HR  LES  VS  LH WIDL FGYK +G  AV+  N
Sbjct: 888  ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 947

Query: 564  VCLH-----------LVDAHTHLASYGVV--------QLFDQPHPQRLAGAPAL 598
            V  +           L D     A  G++        QL  +PHP RL+   A+
Sbjct: 948  VFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAV 1001


>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
            sapiens]
          Length = 3526

 Score =  100 bits (249), Expect = 1e-20
 Identities = 97/301 (32%), Positives = 123/301 (40%), Gaps = 71/301 (23%)

Query: 346  RSLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWV--------VDFTTPHGRFR 397
            +S+   W  G ISNF YLM LN LAGR   D   +PV PW+        VD T P   FR
Sbjct: 2692 KSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPK-TFR 2750

Query: 398  DLRKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPP--HVPHHISDVLSDITYYVYKA 455
            +L K          Q D      ++ +       GE P  H   H S  +   +Y V   
Sbjct: 2751 NLAKPM------GAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLV--- 2801

Query: 456  RRTPRSVLC-----GH----------VRAQWEPHEYPASMERMQNWTPDECIPEFYTDPS 500
            R  P + +      GH          VR  W    Y AS   M +    E IPEF+  P 
Sbjct: 2802 RMEPFTQIFLRLQGGHFDLADRMFHSVREAW----YSASKHNMAD--VKELIPEFFYLPE 2855

Query: 501  -IFRSIHPDMP---------DLDVPAWCSSS-QEFVAAHRALLESREVSRDLHHWIDLTF 549
             +F S + D+          D+ +P W     +EF+  HR  LE   VS  LH WIDL F
Sbjct: 2856 FLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIF 2915

Query: 550  GYKLQGKEAVKEKNVCLHLV-----------DAHTHLASYGVV--------QLFDQPHPQ 590
            GYK QG  AV+  NV  HL            D     A+ G +        QLF +PHP 
Sbjct: 2916 GYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPP 2975

Query: 591  R 591
            +
Sbjct: 2976 K 2976



 Score = 36.2 bits (82), Expect = 0.32
 Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 13/102 (12%)

Query: 1623 YEIGVSQQDAHFHFHQIRL-QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG 1681
            +E+G S++ A      + L Q+  GH+  V C     +    +SGS+DRT  +W L    
Sbjct: 3105 WEMGTSKEKAK----TVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLS 3160

Query: 1682 DGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGA-VHVW 1722
              T           HR  V  +   E    +VSC G  +HVW
Sbjct: 3161 FLTQ-------LRGHRAPVSALCINELTGDIVSCAGTYIHVW 3195


>gi|154240744 neurobeachin-like 1 isoform 2 [Homo sapiens]
          Length = 1335

 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 76/241 (31%), Positives = 109/241 (45%), Gaps = 29/241 (12%)

Query: 348 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 400
           L   WV+  ISNF YL+Q+N +AGR   D   +PV PW++ D+T+          FRDL 
Sbjct: 713 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 772

Query: 401 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 459
           K    +N K  K +   YE           G  +  H   H S+    + Y +     T 
Sbjct: 773 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 827

Query: 460 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 508
             +     R   A  + H  PA+ + + +   D  E IPEF+  P    + +        
Sbjct: 828 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 887

Query: 509 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563
                + D+ +P W  S+++F+  HR  LES  VS  LH WIDL FGYK +G  AV+  N
Sbjct: 888 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 947

Query: 564 V 564
           V
Sbjct: 948 V 948


>gi|191252801 WDFY family member 4 [Homo sapiens]
          Length = 3184

 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 91/305 (29%), Positives = 120/305 (39%), Gaps = 64/305 (20%)

Query: 346  RSLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPHGR------FRD 398
            R ++  W    ISNF YLM LN  AGR   D   +PV PWV+ D+T+          FRD
Sbjct: 2536 RIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLADYTSETLNLANPKIFRD 2595

Query: 399  LRKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRT 458
            L K      K +++L F      Q F       G+     H+ +   S I    Y  R  
Sbjct: 2596 LSKPMGAQTK-ERKLKFI-----QRFKEVEKTEGDMTVQCHYYTHYSSAIIVASYLVRMP 2649

Query: 459  P-RSVLCG--------------HVRAQWEPHEYPASMERMQNWTPDECIPEFYTDPSIFR 503
            P     C                V++ WE     AS E M +    E  PEF+  P    
Sbjct: 2650 PFTQAFCALQGGSFDVADRMFHSVKSTWES----ASRENMSDVR--ELTPEFFYLPEFLT 2703

Query: 504  SIH----------PDMPDLDVPAWCSSS-QEFVAAHRALLESREVSRDLHHWIDLTFGYK 552
            + +            + D+ +P W     ++F++ HR  LES  VS +LHHWIDL FGYK
Sbjct: 2704 NCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDLIFGYK 2763

Query: 553  LQGKEAVKEKNV-----------CLHLVDAHTHLASYGVV--------QLFDQPHPQRLA 593
             QG  AV   N+              + D        G V        QLF +PHP R A
Sbjct: 2764 QQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPHPARTA 2823

Query: 594  GAPAL 598
                L
Sbjct: 2824 AGKPL 2828



 Score = 35.4 bits (80), Expect = 0.55
 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 8/83 (9%)

Query: 1642 QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVF 1701
            Q+  GH+ AV C+A   +    +SGS+D T  LW L +    T   A       HR+ + 
Sbjct: 2976 QALYGHTQAVTCLAASVTFSLLVSGSQDCTCILWDLDHLTHVTRLPA-------HREGIS 3028

Query: 1702 FVGQLEAPQHVVSCDGA-VHVWD 1723
             +   +    +VSC GA + +W+
Sbjct: 3029 AITISDVSGTIVSCAGAHLSLWN 3051


>gi|54292123 lysosomal trafficking regulator [Homo sapiens]
          Length = 3801

 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 83/311 (26%), Positives = 122/311 (39%), Gaps = 54/311 (17%)

Query: 352  WVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPHGRFRDL----RKSK--- 403
            W  G+I+NF YL  LN+ AGR   D   +PV P+++ D+ +      DL      SK   
Sbjct: 3135 WYTGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILADYVSETLDLNDLLIYRNLSKPIA 3194

Query: 404  -FRLNKGDKQLDFTYEMTRQAFVAGGAGGGE-PPHVPHHISDVLSDI-TYYVYKARRTPR 460
                 K D+ +D TY+   + +  G       PP  P+H     S+  T   +  R  P 
Sbjct: 3195 VQYKEKEDRYVD-TYKYLEEEYRKGAREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPF 3253

Query: 461  SVLCGHVRAQWEPHEYPASMERMQNWT-----------PDECIPEFYTDPSIF------- 502
            + +   +  Q +  + P       N T             E IPEF+  P          
Sbjct: 3254 TKM--FLAYQDQSFDIPDRTFHSTNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFD 3311

Query: 503  ---RSIHPDMPDLDVPAWCSSSQE-FVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEA 558
               R     +  +++P W  +    F+  HR  LES  VS+++  WIDL FGYK +GK +
Sbjct: 3312 FGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESDYVSQNICQWIDLVFGYKQKGKAS 3371

Query: 559  VKEKNVC----------------LHLVDAHTHLASYGVV--QLFDQPHPQRLAGAPALAP 600
            V+  NV                 +      T + +YG    QLF   H  R      +  
Sbjct: 3372 VQAINVFHPATYFGMDVSAVEDPVQRRALETMIKTYGQTPRQLFHMAHVSRPGAKLNIEG 3431

Query: 601  EPPLIPKLLVQ 611
            E P    LLVQ
Sbjct: 3432 ELPAAVGLLVQ 3442


>gi|89886480 zinedin isoform 2 [Homo sapiens]
          Length = 760

 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 65/260 (25%), Positives = 102/260 (39%), Gaps = 21/260 (8%)

Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG----DGTSETAPRLVYTQH 1696
            + +F  H G V  VA  S+ ++  SG  D  +  W + +      DG   +    V   H
Sbjct: 491  IHAFRAHRGPVLAVAMGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGH 550

Query: 1697 RKSVFFVGQLEAPQHVVSC--DGAVHVWDPFTGK-----TLRTVEPLDSRVPLTAVAVMP 1749
              +V+ +      Q + SC  DG V +WDP +       T  T         +   +  P
Sbjct: 551  GDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAFTSTEP 610

Query: 1750 APHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGF 1809
            A H   +  S D+ L  ++     L  E R  G   P  +  +   P+    +       
Sbjct: 611  A-HIVASFRSGDTVLYDMEVGSALLTLESR--GSSGPTQINQVVSHPNQPLTITAHDDRG 667

Query: 1810 MVLLDTRTGLVLRGWPAHEGDILQIKAVE--GSVLVSSSSDHSLTVW----KELEQKPTH 1863
            +  LD RTG  +    AH  D +   AV+  G+ L+S S D SL +W    K   Q+ T 
Sbjct: 668  IRFLDNRTGKPVHSMVAHL-DAVTCLAVDPNGAFLMSGSHDCSLRLWSLDNKTCVQEITA 726

Query: 1864 HYKSASDPIHTFDLYGSEVV 1883
            H K   + IH    + S+ +
Sbjct: 727  HRKKHEEAIHAVACHPSKAL 746


>gi|89886477 zinedin isoform 1 [Homo sapiens]
          Length = 753

 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 65/260 (25%), Positives = 102/260 (39%), Gaps = 21/260 (8%)

Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG----DGTSETAPRLVYTQH 1696
            + +F  H G V  VA  S+ ++  SG  D  +  W + +      DG   +    V   H
Sbjct: 484  IHAFRAHRGPVLAVAMGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGH 543

Query: 1697 RKSVFFVGQLEAPQHVVSC--DGAVHVWDPFTGK-----TLRTVEPLDSRVPLTAVAVMP 1749
              +V+ +      Q + SC  DG V +WDP +       T  T         +   +  P
Sbjct: 544  GDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAFTSTEP 603

Query: 1750 APHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGF 1809
            A H   +  S D+ L  ++     L  E R  G   P  +  +   P+    +       
Sbjct: 604  A-HIVASFRSGDTVLYDMEVGSALLTLESR--GSSGPTQINQVVSHPNQPLTITAHDDRG 660

Query: 1810 MVLLDTRTGLVLRGWPAHEGDILQIKAVE--GSVLVSSSSDHSLTVW----KELEQKPTH 1863
            +  LD RTG  +    AH  D +   AV+  G+ L+S S D SL +W    K   Q+ T 
Sbjct: 661  IRFLDNRTGKPVHSMVAHL-DAVTCLAVDPNGAFLMSGSHDCSLRLWSLDNKTCVQEITA 719

Query: 1864 HYKSASDPIHTFDLYGSEVV 1883
            H K   + IH    + S+ +
Sbjct: 720  HRKKHEEAIHAVACHPSKAL 739


>gi|26665869 WD repeat domain 51B [Homo sapiens]
          Length = 478

 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 71/309 (22%), Positives = 122/309 (39%), Gaps = 42/309 (13%)

Query: 1640 RLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKS 1699
            +   F  H+  V+ V   +   F  + S+D+++++W +Y           R +Y+ +R +
Sbjct: 94   KFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQ---------RFLYSLYRHT 144

Query: 1700 VFFVGQLEAPQH--VVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755
             +      +P    +VSC  D  + +WD  T K  + V      V            T I
Sbjct: 145  HWVRCAKFSPDGRLIVSCSEDKTIKIWDT-TNK--QCVNNFSDSVGFANFVDFNPSGTCI 201

Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815
              A SD T++  D R   L   +++    + G V  ++  PSG  ++   S G + +LD 
Sbjct: 202  ASAGSDQTVKVWDVRVNKLLQHYQV----HSGGVNCISFHPSGNYLITASSDGTLKILDL 257

Query: 1816 RTGLVLRGWPAHEGDILQIKAVEGSVL-VSSSSDHSLTVWK----ELEQK-------PTH 1863
              G ++     H G +  +   +G  L  S  +D  + +W+    EL  K          
Sbjct: 258  LEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDELHCKGLTKRNLKRL 317

Query: 1864 HYKSASDPIHTFDLY-------GSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTL 1916
            H+ S   P H  D+Y         +V T  ++ K+ V  L          LS ++   T 
Sbjct: 318  HFDS---PPHLLDIYPRTPHPHEEKVETVEINPKLEVIDLQISTPPVMDILSFDSTTTTE 374

Query: 1917 TSLALLPTK 1925
            TS   LP K
Sbjct: 375  TSGRTLPDK 383


>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
          Length = 369

 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 61/224 (27%), Positives = 88/224 (39%), Gaps = 17/224 (7%)

Query: 1638 QIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHR 1697
            Q R   F GH  AV CV    S     SGS+D+TVR+W     G+ T       V+  H 
Sbjct: 13   QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST-------VFRAHT 65

Query: 1698 KSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755
             +V  V      Q  V  S D  V VW     K L +   L   +     A        I
Sbjct: 66   ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFS---LSQHINWVRCAKFSPDGRLI 122

Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815
              AS D T++  D       H +   G    G V  +   PSG  + A      + + D 
Sbjct: 123  VSASDDKTVKLWDKSSRECVHSYCEHG----GFVTYVDFHPSGTCIAAAGMDNTVKVWDV 178

Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELE 1858
            RT  +L+ +  H   +  +     G+ L+++SSD +L +   +E
Sbjct: 179  RTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLME 222


>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
          Length = 359

 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 61/224 (27%), Positives = 88/224 (39%), Gaps = 17/224 (7%)

Query: 1638 QIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHR 1697
            Q R   F GH  AV CV    S     SGS+D+TVR+W     G+ T       V+  H 
Sbjct: 51   QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST-------VFRAHT 103

Query: 1698 KSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755
             +V  V      Q  V  S D  V VW     K L +   L   +     A        I
Sbjct: 104  ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFS---LSQHINWVRCAKFSPDGRLI 160

Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815
              AS D T++  D       H +   G    G V  +   PSG  + A      + + D 
Sbjct: 161  VSASDDKTVKLWDKSSRECVHSYCEHG----GFVTYVDFHPSGTCIAAAGMDNTVKVWDV 216

Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELE 1858
            RT  +L+ +  H   +  +     G+ L+++SSD +L +   +E
Sbjct: 217  RTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLME 260



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 57/266 (21%), Positives = 104/266 (39%), Gaps = 31/266 (11%)

Query: 1644 FPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVFFV 1703
            F GH  AV CV    +     SGS D  + +W +          +    +T H+ +V  V
Sbjct: 15   FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHM-------KPQSRAYRFTGHKDAVTCV 67

Query: 1704 GQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPH-----TSI 1755
                   H++   S D  V +W P            +S V     A + + H      S 
Sbjct: 68   -NFSPSGHLLASGSRDKTVRIWVPNVKG--------ESTVFRAHTATVRSVHFCSDGQSF 118

Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815
              AS D T++     +   +  F L   +N   VR    SP GR +V+      + L D 
Sbjct: 119  VTASDDKTVKVWATHRQ--KFLFSLSQHIN--WVRCAKFSPDGRLIVSASDDKTVKLWDK 174

Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELEQKPTHHYKSASDPIH- 1873
             +   +  +  H G +  +     G+ + ++  D+++ VW     +   HY+  S  ++ 
Sbjct: 175  SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 234

Query: 1874 -TFDLYGSEVVTGTVSNKIGVCSLLE 1898
             +F   G+ ++T +  + + +  L+E
Sbjct: 235  LSFHPSGNYLITASSDSTLKILDLME 260


>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
          Length = 407

 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 61/224 (27%), Positives = 88/224 (39%), Gaps = 17/224 (7%)

Query: 1638 QIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHR 1697
            Q R   F GH  AV CV    S     SGS+D+TVR+W     G+ T       V+  H 
Sbjct: 51   QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST-------VFRAHT 103

Query: 1698 KSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755
             +V  V      Q  V  S D  V VW     K L +   L   +     A        I
Sbjct: 104  ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFS---LSQHINWVRCAKFSPDGRLI 160

Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815
              AS D T++  D       H +   G    G V  +   PSG  + A      + + D 
Sbjct: 161  VSASDDKTVKLWDKSSRECVHSYCEHG----GFVTYVDFHPSGTCIAAAGMDNTVKVWDV 216

Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELE 1858
            RT  +L+ +  H   +  +     G+ L+++SSD +L +   +E
Sbjct: 217  RTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLME 260



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 57/266 (21%), Positives = 104/266 (39%), Gaps = 31/266 (11%)

Query: 1644 FPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVFFV 1703
            F GH  AV CV    +     SGS D  + +W +          +    +T H+ +V  V
Sbjct: 15   FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHM-------KPQSRAYRFTGHKDAVTCV 67

Query: 1704 GQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPH-----TSI 1755
                   H++   S D  V +W P            +S V     A + + H      S 
Sbjct: 68   -NFSPSGHLLASGSRDKTVRIWVPNVKG--------ESTVFRAHTATVRSVHFCSDGQSF 118

Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815
              AS D T++     +   +  F L   +N   VR    SP GR +V+      + L D 
Sbjct: 119  VTASDDKTVKVWATHRQ--KFLFSLSQHIN--WVRCAKFSPDGRLIVSASDDKTVKLWDK 174

Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELEQKPTHHYKSASDPIH- 1873
             +   +  +  H G +  +     G+ + ++  D+++ VW     +   HY+  S  ++ 
Sbjct: 175  SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 234

Query: 1874 -TFDLYGSEVVTGTVSNKIGVCSLLE 1898
             +F   G+ ++T +  + + +  L+E
Sbjct: 235  LSFHPSGNYLITASSDSTLKILDLME 260


>gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens]
          Length = 919

 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 14/223 (6%)

Query: 1639 IRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1698
            +R +    H G++ CVA         +GS D+ V++ P     +  + T P L ++ H  
Sbjct: 652  VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPF--NAETCNATGPDLEFSMHDG 709

Query: 1699 SVFFVGQLEAPQH----VVSC---DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAP 1751
            ++  +  +E P+     ++S    D  ++  D   G+ L  +      +    +A+    
Sbjct: 710  TIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI----LALYTWS 765

Query: 1752 HTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMV 1811
               I   S D T+RF D R P                V ++A+ PSGR +  G      +
Sbjct: 766  GWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCM 825

Query: 1812 LLDTRTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTV 1853
            L D R G +++ +  H  D+  ++   G+  L++ S D  + V
Sbjct: 826  LYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 868


>gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens]
          Length = 927

 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 14/223 (6%)

Query: 1639 IRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1698
            +R +    H G++ CVA         +GS D+ V++ P     +  + T P L ++ H  
Sbjct: 660  VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPF--NAETCNATGPDLEFSMHDG 717

Query: 1699 SVFFVGQLEAPQH----VVSC---DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAP 1751
            ++  +  +E P+     ++S    D  ++  D   G+ L  +      +    +A+    
Sbjct: 718  TIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI----LALYTWS 773

Query: 1752 HTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMV 1811
               I   S D T+RF D R P                V ++A+ PSGR +  G      +
Sbjct: 774  GWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCM 833

Query: 1812 LLDTRTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTV 1853
            L D R G +++ +  H  D+  ++   G+  L++ S D  + V
Sbjct: 834  LYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 876


>gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens]
          Length = 920

 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 14/223 (6%)

Query: 1639 IRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1698
            +R +    H G++ CVA         +GS D+ V++ P     +  + T P L ++ H  
Sbjct: 653  VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPF--NAETCNATGPDLEFSMHDG 710

Query: 1699 SVFFVGQLEAPQH----VVSC---DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAP 1751
            ++  +  +E P+     ++S    D  ++  D   G+ L  +      +    +A+    
Sbjct: 711  TIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI----LALYTWS 766

Query: 1752 HTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMV 1811
               I   S D T+RF D R P                V ++A+ PSGR +  G      +
Sbjct: 767  GWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCM 826

Query: 1812 LLDTRTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTV 1853
            L D R G +++ +  H  D+  ++   G+  L++ S D  + V
Sbjct: 827  LYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 869


>gi|21071067 TBP-associated factor 5 [Homo sapiens]
          Length = 800

 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 64/253 (25%), Positives = 107/253 (42%), Gaps = 25/253 (9%)

Query: 1646 GHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLV-YTQHRKSVFFVG 1704
            GHSG V   +     ++ LS S+D TVRLW L        +T   LV Y  H   V+   
Sbjct: 541  GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL--------QTFTCLVGYKGHNYPVWDTQ 592

Query: 1705 QLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTS-ITMASSD 1761
                  + VS   D    +W     + LR      + V  T       P+++ +   S+D
Sbjct: 593  FSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFH----PNSNYVATGSAD 648

Query: 1762 STLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTGLVL 1821
             T+R  D         F      + G + +L  SP+GR +  G + G ++L D   GL++
Sbjct: 649  RTVRLWDVLNGNCVRIFTG----HKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMV 704

Query: 1822 RGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVW---KELEQKPTHHYKSASDPIHTFDL 1877
                 H   +  ++ + +G +L S S D+++ +W   K  E   T  + +A+  I+  + 
Sbjct: 705  GELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPE- 763

Query: 1878 YGSEVVTGTVSNK 1890
               E++ GT   K
Sbjct: 764  NSQELLLGTYMTK 776



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 17/45 (37%), Positives = 25/45 (55%), Gaps = 2/45 (4%)

Query: 1635 HFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYN 1679
            H+  +R+  F GH   V C     + ++  +GS DRTVRLW + N
Sbjct: 616  HYQPLRI--FAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658


>gi|38569484 kinesin family member 21A [Homo sapiens]
          Length = 1661

 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 56/236 (23%), Positives = 95/236 (40%), Gaps = 28/236 (11%)

Query: 1646 GHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGD-----GTSETAPRLVYTQHRKSV 1700
            GH+ AV CV   S++D   +GSKDRT ++W L    +     G       + Y  +   V
Sbjct: 1332 GHTKAVLCVD--STDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLV 1389

Query: 1701 FFVGQLEAPQ----------HVVSCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPA 1750
            F V                   ++  G V + D  +  T RTV        +  +A+ P 
Sbjct: 1390 FTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQINQIALNPT 1449

Query: 1751 PHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS-VVAGFSSGF 1809
               +   A+S + +R  D ++   Q   +L G L P +   +    SG+  ++ G    +
Sbjct: 1450 --GTFLYAASGNAVRMWDLKR--FQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDHY 1505

Query: 1810 MVLLDTRTGLVLRGWPAH-----EGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
            + + D   G +    P H       D ++   ++G  L S S D+ +  W +L QK
Sbjct: 1506 IKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKW-DLTQK 1560


>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
          Length = 655

 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 52/220 (23%), Positives = 91/220 (41%), Gaps = 20/220 (9%)

Query: 1640 RLQSFPGHSGAVKC-VAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1698
            +LQ    H+  V   V   +S     +G  D  V LW +       S T     +T   +
Sbjct: 12   KLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTG----HTSPVE 67

Query: 1699 SVFFVGQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755
            SV    +L  P+ ++   S  G++ VWD    K LRT+  +  +  + ++   P     +
Sbjct: 68   SV----RLNTPEELIVAGSQSGSIRVWDLEAAKILRTL--MGHKANICSLDFHPYGEF-V 120

Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815
               S D+ ++  D R+ G    +R     +   VR L  SP G+ + +      + L D 
Sbjct: 121  ASGSQDTNIKLWDIRRKGCVFRYRG----HSQAVRCLRFSPDGKWLASAADDHTVKLWDL 176

Query: 1816 RTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTVW 1854
              G ++  +P H G +  ++      +L S SSD ++  W
Sbjct: 177  TAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFW 216



 Score = 38.5 bits (88), Expect = 0.065
 Identities = 17/40 (42%), Positives = 22/40 (55%)

Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680
            +  FPGH+G V  V    +E    SGS DRT+R W L  +
Sbjct: 182  MSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKF 221


>gi|16554629 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 57/239 (23%), Positives = 98/239 (41%), Gaps = 35/239 (14%)

Query: 1642 QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVF 1701
            ++  GH   +  VA  S  +  +S S D+T+++W +         +   L   +   +  
Sbjct: 81   KTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV--------SSGKCLKTLKGHSNYV 132

Query: 1702 FVGQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 1758
            F        +++   S D +V +WD  TGK L+T+ P  S  P++AV       + I  +
Sbjct: 133  FCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL-PAHSD-PVSAVH-FNRDGSLIVSS 189

Query: 1759 SSDSTLRFVD-----CRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLL 1813
            S D   R  D     C K  +  +       NP  V  +  SP+G+ ++A      + L 
Sbjct: 190  SYDGLCRIWDTASGQCLKTLIDDD-------NPP-VSFVKFSPNGKYILAATLDNTLKLW 241

Query: 1814 DTRTGLVLRGWPAHEGD----ILQIKAVEGSVLVSSSSDHSLTVW----KELEQKPTHH 1864
            D   G  L+ +  H+ +            G  +VS S D+ + +W    KE+ QK   H
Sbjct: 242  DYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH 300



 Score = 40.0 bits (92), Expect = 0.022
 Identities = 50/220 (22%), Positives = 91/220 (41%), Gaps = 15/220 (6%)

Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSV 1700
            L++  GHS  V C       +  +SGS D +VR+W +        +T P      H   V
Sbjct: 122  LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT--GKCLKTLP-----AHSDPV 174

Query: 1701 FFVGQLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 1758
              V        +VS   DG   +WD  +G+ L+T+   D   P++ V   P     I  A
Sbjct: 175  SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID-DDNPPVSFVKFSP-NGKYILAA 232

Query: 1759 SSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTG 1818
            + D+TL+  D  K G   +   G       + A      G+ +V+G     + + + +T 
Sbjct: 233  TLDNTLKLWDYSK-GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTK 291

Query: 1819 LVLRGWPAHEGDILQIKAVEGSVLVSSS---SDHSLTVWK 1855
             +++    H   ++         +++S+   +D ++ +WK
Sbjct: 292  EIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331


>gi|16554627 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 57/239 (23%), Positives = 98/239 (41%), Gaps = 35/239 (14%)

Query: 1642 QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVF 1701
            ++  GH   +  VA  S  +  +S S D+T+++W +         +   L   +   +  
Sbjct: 81   KTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV--------SSGKCLKTLKGHSNYV 132

Query: 1702 FVGQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 1758
            F        +++   S D +V +WD  TGK L+T+ P  S  P++AV       + I  +
Sbjct: 133  FCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL-PAHSD-PVSAVH-FNRDGSLIVSS 189

Query: 1759 SSDSTLRFVD-----CRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLL 1813
            S D   R  D     C K  +  +       NP  V  +  SP+G+ ++A      + L 
Sbjct: 190  SYDGLCRIWDTASGQCLKTLIDDD-------NPP-VSFVKFSPNGKYILAATLDNTLKLW 241

Query: 1814 DTRTGLVLRGWPAHEGD----ILQIKAVEGSVLVSSSSDHSLTVW----KELEQKPTHH 1864
            D   G  L+ +  H+ +            G  +VS S D+ + +W    KE+ QK   H
Sbjct: 242  DYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH 300



 Score = 40.0 bits (92), Expect = 0.022
 Identities = 50/220 (22%), Positives = 91/220 (41%), Gaps = 15/220 (6%)

Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSV 1700
            L++  GHS  V C       +  +SGS D +VR+W +        +T P      H   V
Sbjct: 122  LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT--GKCLKTLP-----AHSDPV 174

Query: 1701 FFVGQLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 1758
              V        +VS   DG   +WD  +G+ L+T+   D   P++ V   P     I  A
Sbjct: 175  SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID-DDNPPVSFVKFSP-NGKYILAA 232

Query: 1759 SSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTG 1818
            + D+TL+  D  K G   +   G       + A      G+ +V+G     + + + +T 
Sbjct: 233  TLDNTLKLWDYSK-GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTK 291

Query: 1819 LVLRGWPAHEGDILQIKAVEGSVLVSSS---SDHSLTVWK 1855
             +++    H   ++         +++S+   +D ++ +WK
Sbjct: 292  EIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331


>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
          Length = 517

 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 44/146 (30%), Positives = 64/146 (43%), Gaps = 12/146 (8%)

Query: 1064 LPDYTSGVSFHDQADLPETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEER 1123
            LP  + G +   +A+ PE E+ +      E  +  EAEAV+   L+  S       G   
Sbjct: 20   LPPGSPGSAARGRAEPPEEEEEEE-----EEEEEAEAEAVAALLLNGGSGGG----GGGG 70

Query: 1124 APDEGGAPVDKSSLRSGDSSQDLKQSEGSEE---EEEEEDSCVVLEEEEGEQEEVTGASE 1180
                GG   +  S  S +S+    + E  EE   EEE+E S     EEE   E + G+S 
Sbjct: 71   GGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSG 130

Query: 1181 LTLSDTVLSMETVVAGGSGGDGEEEE 1206
             + SD   S+    A  S GDG+ +E
Sbjct: 131  GSSSDETRSLSPGAASSSSGDGDGKE 156


>gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]
          Length = 234

 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 31/81 (38%), Positives = 43/81 (53%), Gaps = 6/81 (7%)

Query: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200
            D  + L   E  E EEE ++   V+E+EEGE+EE  G  E    D     E    G + G
Sbjct: 158  DHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEE----DVSGGDEEDEEGYNDG 213

Query: 1201 --DGEEEEEALPEQSEGKEQK 1219
              DGEE+EE L E+  G+++K
Sbjct: 214  EVDGEEDEEELGEEERGQKRK 234


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,716,414
Number of Sequences: 37866
Number of extensions: 4590288
Number of successful extensions: 26994
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 151
Number of HSP's successfully gapped in prelim test: 369
Number of HSP's that attempted gapping in prelim test: 21144
Number of HSP's gapped (non-prelim): 3345
length of query: 1941
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1824
effective length of database: 13,817,196
effective search space: 25202565504
effective search space used: 25202565504
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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