BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens] (1941 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens] 3922 0.0 gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens] 3922 0.0 gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens] 3922 0.0 gi|149944548 neurobeachin-like 2 [Homo sapiens] 107 1e-22 gi|148233596 LPS-responsive vesicle trafficking, beach and ancho... 105 4e-22 gi|31543297 neutral sphingomyelinase (N-SMase) activation associ... 104 7e-22 gi|221625547 neutral sphingomyelinase (N-SMase) activation assoc... 104 7e-22 gi|62422577 neurobeachin [Homo sapiens] 103 1e-21 gi|224451124 neurobeachin-like 1 isoform 3 [Homo sapiens] 102 4e-21 gi|149944613 neurobeachin-like 1 isoform 1 [Homo sapiens] 102 4e-21 gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 100 1e-20 gi|154240744 neurobeachin-like 1 isoform 2 [Homo sapiens] 96 3e-19 gi|191252801 WDFY family member 4 [Homo sapiens] 90 2e-17 gi|54292123 lysosomal trafficking regulator [Homo sapiens] 69 4e-11 gi|89886480 zinedin isoform 2 [Homo sapiens] 62 4e-09 gi|89886477 zinedin isoform 1 [Homo sapiens] 62 4e-09 gi|26665869 WD repeat domain 51B [Homo sapiens] 61 1e-08 gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 59 5e-08 gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 59 5e-08 gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 59 5e-08 gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens] 56 4e-07 gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens] 56 4e-07 gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens] 56 4e-07 gi|21071067 TBP-associated factor 5 [Homo sapiens] 52 6e-06 gi|38569484 kinesin family member 21A [Homo sapiens] 51 1e-05 gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 49 4e-05 gi|16554629 WD repeat domain 5 [Homo sapiens] 49 6e-05 gi|16554627 WD repeat domain 5 [Homo sapiens] 49 6e-05 gi|166795264 AE binding protein 2 isoform b [Homo sapiens] 49 6e-05 gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens] 49 6e-05 >gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens] Length = 1941 Score = 3922 bits (10170), Expect = 0.0 Identities = 1941/1941 (100%), Positives = 1941/1941 (100%) Query: 1 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA Sbjct: 1 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60 Query: 61 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG Sbjct: 61 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120 Query: 121 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA Sbjct: 121 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180 Query: 181 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF Sbjct: 181 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240 Query: 241 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR Sbjct: 241 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300 Query: 301 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF Sbjct: 301 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360 Query: 361 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT Sbjct: 361 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420 Query: 421 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM Sbjct: 421 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480 Query: 481 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD Sbjct: 481 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540 Query: 541 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP Sbjct: 541 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600 Query: 601 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE Sbjct: 601 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660 Query: 661 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL Sbjct: 661 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720 Query: 721 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE Sbjct: 721 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780 Query: 781 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG Sbjct: 781 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840 Query: 841 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE Sbjct: 841 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900 Query: 901 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK Sbjct: 901 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960 Query: 961 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE Sbjct: 961 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020 Query: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP Sbjct: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080 Query: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG Sbjct: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140 Query: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG Sbjct: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200 Query: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP Sbjct: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260 Query: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS Sbjct: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320 Query: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL Sbjct: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380 Query: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ Sbjct: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440 Query: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII Sbjct: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500 Query: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG Sbjct: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560 Query: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY Sbjct: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620 Query: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY Sbjct: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680 Query: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV Sbjct: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740 Query: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS Sbjct: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800 Query: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK Sbjct: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860 Query: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA Sbjct: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920 Query: 1921 LLPTKRHLLLGSDNGVIRLLA 1941 LLPTKRHLLLGSDNGVIRLLA Sbjct: 1921 LLPTKRHLLLGSDNGVIRLLA 1941 >gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens] Length = 2240 Score = 3922 bits (10170), Expect = 0.0 Identities = 1941/1941 (100%), Positives = 1941/1941 (100%) Query: 1 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA Sbjct: 300 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 359 Query: 61 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG Sbjct: 360 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 419 Query: 121 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA Sbjct: 420 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 479 Query: 181 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF Sbjct: 480 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 539 Query: 241 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR Sbjct: 540 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 599 Query: 301 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF Sbjct: 600 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 659 Query: 361 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT Sbjct: 660 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 719 Query: 421 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM Sbjct: 720 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 779 Query: 481 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD Sbjct: 780 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 839 Query: 541 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP Sbjct: 840 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 899 Query: 601 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE Sbjct: 900 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 959 Query: 661 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL Sbjct: 960 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 1019 Query: 721 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE Sbjct: 1020 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 1079 Query: 781 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG Sbjct: 1080 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 1139 Query: 841 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE Sbjct: 1140 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 1199 Query: 901 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK Sbjct: 1200 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 1259 Query: 961 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE Sbjct: 1260 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1319 Query: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP Sbjct: 1320 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1379 Query: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG Sbjct: 1380 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1439 Query: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG Sbjct: 1440 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1499 Query: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP Sbjct: 1500 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1559 Query: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS Sbjct: 1560 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1619 Query: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL Sbjct: 1620 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1679 Query: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ Sbjct: 1680 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1739 Query: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII Sbjct: 1740 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1799 Query: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG Sbjct: 1800 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1859 Query: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY Sbjct: 1860 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1919 Query: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY Sbjct: 1920 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1979 Query: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV Sbjct: 1980 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 2039 Query: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS Sbjct: 2040 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 2099 Query: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK Sbjct: 2100 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 2159 Query: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA Sbjct: 2160 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 2219 Query: 1921 LLPTKRHLLLGSDNGVIRLLA 1941 LLPTKRHLLLGSDNGVIRLLA Sbjct: 2220 LLPTKRHLLLGSDNGVIRLLA 2240 >gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens] Length = 1941 Score = 3922 bits (10170), Expect = 0.0 Identities = 1941/1941 (100%), Positives = 1941/1941 (100%) Query: 1 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA Sbjct: 1 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60 Query: 61 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG Sbjct: 61 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120 Query: 121 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA Sbjct: 121 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180 Query: 181 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF Sbjct: 181 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240 Query: 241 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR Sbjct: 241 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300 Query: 301 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF Sbjct: 301 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360 Query: 361 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT Sbjct: 361 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420 Query: 421 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM Sbjct: 421 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480 Query: 481 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD Sbjct: 481 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540 Query: 541 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP Sbjct: 541 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600 Query: 601 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE Sbjct: 601 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660 Query: 661 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL Sbjct: 661 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720 Query: 721 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE Sbjct: 721 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780 Query: 781 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG Sbjct: 781 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840 Query: 841 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE Sbjct: 841 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900 Query: 901 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK Sbjct: 901 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960 Query: 961 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE Sbjct: 961 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020 Query: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP Sbjct: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080 Query: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG Sbjct: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140 Query: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG Sbjct: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200 Query: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP Sbjct: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260 Query: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS Sbjct: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320 Query: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL Sbjct: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380 Query: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ Sbjct: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440 Query: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII Sbjct: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500 Query: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG Sbjct: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560 Query: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY Sbjct: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620 Query: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY Sbjct: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680 Query: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV Sbjct: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740 Query: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS Sbjct: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800 Query: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK Sbjct: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860 Query: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA Sbjct: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920 Query: 1921 LLPTKRHLLLGSDNGVIRLLA 1941 LLPTKRHLLLGSDNGVIRLLA Sbjct: 1921 LLPTKRHLLLGSDNGVIRLLA 1941 >gi|149944548 neurobeachin-like 2 [Homo sapiens] Length = 2754 Score = 107 bits (267), Expect = 1e-22 Identities = 97/310 (31%), Positives = 131/310 (42%), Gaps = 68/310 (21%) Query: 342 QEELRS--LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH----- 393 QE LR+ L WV ISNF YLMQLN +AGR D + +PV PWV+ D+ +P Sbjct: 2056 QEMLRASGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPTLDLSN 2115 Query: 394 -GRFRDLRKSKFRLNKGDKQLDFTYEMTRQAFVA--GGAGGGEPPHVPHHISDVLSDITY 450 FRDL K +N QL R+ + + AG + H H S+ + Y Sbjct: 2116 PAVFRDLSKPIGVVNPKHAQL------VREKYESFEDPAGTIDKFHYGTHYSNAAGVMHY 2169 Query: 451 YVYKARRTPRSVL-------CGH-----VRAQWEPH-EYPASMERMQNWTPDECIPEFYT 497 + T V C V A W+ E PA ++ E IPEF+ Sbjct: 2170 LIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQARLESPADVK--------ELIPEFFY 2221 Query: 498 DPSIFRS-----------IHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWID 546 P + + + D+ +P W SS ++F+ HR LES VS LH WID Sbjct: 2222 FPDFLENQNGFDLGCLQLTNEKVGDVVLPPWASSPEDFIQQHRQALESEYVSAHLHEWID 2281 Query: 547 LTFGYKLQGKEAVKEKNVCL-----------HLVDAHTHLASYGVV--------QLFDQP 587 L FGYK +G A + NV H+ D A G++ QL +P Sbjct: 2282 LIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVTDERERKALEGIISNFGQTPCQLLKEP 2341 Query: 588 HPQRLAGAPA 597 HP RL+ A Sbjct: 2342 HPTRLSAEEA 2351 Score = 32.7 bits (73), Expect = 3.5 Identities = 57/236 (24%), Positives = 84/236 (35%), Gaps = 38/236 (16%) Query: 1580 GPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAYWQYEIGVSQQDAHFHFHQI 1639 GP P SGV G L D L SG +W + V+ Q+ Sbjct: 2452 GPWVPGSGVSGQALAVAPDGKLL----------FSGG---HWDGSLRVTALPRGKLLSQL 2498 Query: 1640 RLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYT--QHR 1697 H V C+A + + +SGS+D T +W L + G + AP+ V H Sbjct: 2499 SC-----HLDVVTCLALDTCGIYLISGSRDTTCMVWRLLHQGGLSVGLAPKPVQVLYGHG 2553 Query: 1698 KSVFFVGQLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755 +V V VS DG V + G+ + + PL A P P + Sbjct: 2554 AAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPLG--------ATFPGPIFHL 2605 Query: 1756 TMASSDS-TLRFVDCRKPGLQ-----HEFRLGGGLNPGLVRALAISPSGRSVVAGF 1805 + S ++ +PG Q H + + G L L LA P+ +V F Sbjct: 2606 ALGSEGQIVVQSSAWERPGAQVTYSLHLYSVNGKLRASL--PLAEQPTALTVTEDF 2659 >gi|148233596 LPS-responsive vesicle trafficking, beach and anchor containing [Homo sapiens] Length = 2863 Score = 105 bits (262), Expect = 4e-22 Identities = 93/287 (32%), Positives = 120/287 (41%), Gaps = 59/287 (20%) Query: 352 WVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRDLRKSK 403 W H ISNF YLM LN +AGR D N +PV PWV+ D T P FRDL K Sbjct: 2215 WQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPTN-FRDLSKPI 2273 Query: 404 FRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPH-HISDVLSDITYYV-YKARRTPRS 461 LN R AF A E VP H S ++ + + R P + Sbjct: 2274 GALNP-----------KRAAFFAERYESWEDDQVPKFHYGTHYSTASFVLAWLLRIEPFT 2322 Query: 462 VLCGHVRAQWEPHEYPASMERMQNW------TPD--ECIPEFYTDPSIFRSIH------- 506 +++ H + W T D E IPEFY P +F + + Sbjct: 2323 TYFLNLQGGKFDHADRTFSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVM 2382 Query: 507 ---PDMPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563 + D+++P W +S+EFV +R LES VS LH WIDL FGYK QG EAV+ N Sbjct: 2383 DDGTVVSDVELPPWAKTSEEFVHINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALN 2442 Query: 564 VCLHLV-----------------DAHTHLASYGVV--QLFDQPHPQR 591 V +L + S+G QL +PHP R Sbjct: 2443 VFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPR 2489 >gi|31543297 neutral sphingomyelinase (N-SMase) activation associated factor isoform 1 [Homo sapiens] Length = 917 Score = 104 bits (260), Expect = 7e-22 Identities = 87/286 (30%), Positives = 127/286 (44%), Gaps = 49/286 (17%) Query: 347 SLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRD 398 S +L W G +SN+ YL+ LN LA R D + +PV PW++ D + P G FRD Sbjct: 300 SYMLQWQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWIIHDYSSSELDLSNP-GTFRD 358 Query: 399 LRKSKFRLNKG--DKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKAR 456 L K LNK ++ L EM F+ G + P +V ++ + + + R Sbjct: 359 LSKPVGALNKERLERLLTRYQEMPEPKFMYG-SHYSSPGYVLFYLVRIAPEYMLCLQNGR 417 Query: 457 RTPRSVLCGHVRAQWEPHEYPASMERMQNWTPDECIPEFYTDPSIF--RSIHPDM----- 509 + + W+ A+ + E IPEFY D F S+ D+ Sbjct: 418 FDNADRMFNSIAETWKNCLDGATDFK-------ELIPEFYGDDVSFLVNSLKLDLGKRQG 470 Query: 510 ----PDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKNVC 565 D+++P W SS ++F+ + LES VS LH WIDL FGYK +G +AV NV Sbjct: 471 GQMVDDVELPPWASSPEDFLQKSKDALESNYVSEHLHEWIDLIFGYKQKGSDAVGAHNVF 530 Query: 566 LHL-----VDAH------------THLASYGVV--QLFDQPHPQRL 592 L VD + T + +G QLF PHP+R+ Sbjct: 531 HPLTYEGGVDLNSIQDPDEKVAMLTQILEFGQTPKQLFVTPHPRRI 576 Score = 35.8 bits (81), Expect = 0.42 Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 14/154 (9%) Query: 1714 SCDGAVHVWDPFTGKTLRT-------VEPLDSRVPLTAVAVMPAPHTSITMASSDSTLRF 1766 S D V VW + T + L+ V + ++ + A T + + + T+ Sbjct: 731 SWDSTVKVWSGVPAEMPGTKRHHFDLLAELEHDVSVDTIS-LNAASTLLVSGTKEGTVNI 789 Query: 1767 VDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPA 1826 D L H+ + G+V A SP R V++ + G + ++D +TG+++ + Sbjct: 790 WDLTTATLMHQIPC----HSGIVCDTAFSPDSRHVLSTGTDGCLNVIDVQTGMLISSMTS 845 Query: 1827 HEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860 E + +G+ ++S S L VW L K Sbjct: 846 DEPQ--RCFVWDGNSVLSGSQSGELLVWDLLGAK 877 >gi|221625547 neutral sphingomyelinase (N-SMase) activation associated factor isoform 2 [Homo sapiens] Length = 948 Score = 104 bits (260), Expect = 7e-22 Identities = 87/286 (30%), Positives = 127/286 (44%), Gaps = 49/286 (17%) Query: 347 SLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRD 398 S +L W G +SN+ YL+ LN LA R D + +PV PW++ D + P G FRD Sbjct: 331 SYMLQWQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWIIHDYSSSELDLSNP-GTFRD 389 Query: 399 LRKSKFRLNKG--DKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKAR 456 L K LNK ++ L EM F+ G + P +V ++ + + + R Sbjct: 390 LSKPVGALNKERLERLLTRYQEMPEPKFMYG-SHYSSPGYVLFYLVRIAPEYMLCLQNGR 448 Query: 457 RTPRSVLCGHVRAQWEPHEYPASMERMQNWTPDECIPEFYTDPSIF--RSIHPDM----- 509 + + W+ A+ + E IPEFY D F S+ D+ Sbjct: 449 FDNADRMFNSIAETWKNCLDGATDFK-------ELIPEFYGDDVSFLVNSLKLDLGKRQG 501 Query: 510 ----PDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKNVC 565 D+++P W SS ++F+ + LES VS LH WIDL FGYK +G +AV NV Sbjct: 502 GQMVDDVELPPWASSPEDFLQKSKDALESNYVSEHLHEWIDLIFGYKQKGSDAVGAHNVF 561 Query: 566 LHL-----VDAH------------THLASYGVV--QLFDQPHPQRL 592 L VD + T + +G QLF PHP+R+ Sbjct: 562 HPLTYEGGVDLNSIQDPDEKVAMLTQILEFGQTPKQLFVTPHPRRI 607 Score = 35.8 bits (81), Expect = 0.42 Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 14/154 (9%) Query: 1714 SCDGAVHVWDPFTGKTLRT-------VEPLDSRVPLTAVAVMPAPHTSITMASSDSTLRF 1766 S D V VW + T + L+ V + ++ + A T + + + T+ Sbjct: 762 SWDSTVKVWSGVPAEMPGTKRHHFDLLAELEHDVSVDTIS-LNAASTLLVSGTKEGTVNI 820 Query: 1767 VDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPA 1826 D L H+ + G+V A SP R V++ + G + ++D +TG+++ + Sbjct: 821 WDLTTATLMHQIPC----HSGIVCDTAFSPDSRHVLSTGTDGCLNVIDVQTGMLISSMTS 876 Query: 1827 HEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860 E + +G+ ++S S L VW L K Sbjct: 877 DEPQ--RCFVWDGNSVLSGSQSGELLVWDLLGAK 908 >gi|62422577 neurobeachin [Homo sapiens] Length = 2946 Score = 103 bits (258), Expect = 1e-21 Identities = 96/299 (32%), Positives = 127/299 (42%), Gaps = 50/299 (16%) Query: 352 WVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRDLRKSK 403 W ISNF YLM LN +AGR D N +PV PWV+ D T P G FRDL K Sbjct: 2289 WQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLP-GNFRDLSKPI 2347 Query: 404 FRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVL 463 LN K+ F E + P H H S S +++ V T + Sbjct: 2348 GALNP--KRAVFYAER----YETWEDDQSPPYHYNTHYSTATSTLSWLVRIEPFTTFFLN 2401 Query: 464 CGHVRAQWEPHEYPA---SMERMQNWTPD--ECIPEFYTDPSIF----------RSIHPD 508 + + + S Q T D E IPEFY P +F R Sbjct: 2402 ANDGKFDHPDRTFSSVARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNLGVREDEVV 2461 Query: 509 MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKNVCLHL 568 + D+D+P W ++FV +R LES VS LH WIDL FGYK +G EAV+ NV +L Sbjct: 2462 VNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYL 2521 Query: 569 -------VDAHT----------HLASYGVV--QLFDQPHPQRLAGAP-ALAPEPPLIPK 607 +D+ T + ++G QL +PHP R + P+ PL+ K Sbjct: 2522 TYEGSVNLDSITDPVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFK 2580 >gi|224451124 neurobeachin-like 1 isoform 3 [Homo sapiens] Length = 2694 Score = 102 bits (254), Expect = 4e-21 Identities = 88/294 (29%), Positives = 127/294 (43%), Gaps = 48/294 (16%) Query: 348 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 400 L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL Sbjct: 2003 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 2062 Query: 401 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 459 K +N K K + YE G + H H S+ + Y + T Sbjct: 2063 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 2117 Query: 460 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 508 + R A + H PA+ + + + D E IPEF+ P + + Sbjct: 2118 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 2177 Query: 509 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563 + D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N Sbjct: 2178 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 2237 Query: 564 VCLH-----------LVDAHTHLASYGVV--------QLFDQPHPQRLAGAPAL 598 V + L D A G++ QL +PHP RL+ A+ Sbjct: 2238 VFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAV 2291 >gi|149944613 neurobeachin-like 1 isoform 1 [Homo sapiens] Length = 1404 Score = 102 bits (254), Expect = 4e-21 Identities = 88/294 (29%), Positives = 127/294 (43%), Gaps = 48/294 (16%) Query: 348 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 400 L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL Sbjct: 713 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 772 Query: 401 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 459 K +N K K + YE G + H H S+ + Y + T Sbjct: 773 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 827 Query: 460 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 508 + R A + H PA+ + + + D E IPEF+ P + + Sbjct: 828 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 887 Query: 509 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563 + D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N Sbjct: 888 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 947 Query: 564 VCLH-----------LVDAHTHLASYGVV--------QLFDQPHPQRLAGAPAL 598 V + L D A G++ QL +PHP RL+ A+ Sbjct: 948 VFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAV 1001 >gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo sapiens] Length = 3526 Score = 100 bits (249), Expect = 1e-20 Identities = 97/301 (32%), Positives = 123/301 (40%), Gaps = 71/301 (23%) Query: 346 RSLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWV--------VDFTTPHGRFR 397 +S+ W G ISNF YLM LN LAGR D +PV PW+ VD T P FR Sbjct: 2692 KSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPK-TFR 2750 Query: 398 DLRKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPP--HVPHHISDVLSDITYYVYKA 455 +L K Q D ++ + GE P H H S + +Y V Sbjct: 2751 NLAKPM------GAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLV--- 2801 Query: 456 RRTPRSVLC-----GH----------VRAQWEPHEYPASMERMQNWTPDECIPEFYTDPS 500 R P + + GH VR W Y AS M + E IPEF+ P Sbjct: 2802 RMEPFTQIFLRLQGGHFDLADRMFHSVREAW----YSASKHNMAD--VKELIPEFFYLPE 2855 Query: 501 -IFRSIHPDMP---------DLDVPAWCSSS-QEFVAAHRALLESREVSRDLHHWIDLTF 549 +F S + D+ D+ +P W +EF+ HR LE VS LH WIDL F Sbjct: 2856 FLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIF 2915 Query: 550 GYKLQGKEAVKEKNVCLHLV-----------DAHTHLASYGVV--------QLFDQPHPQ 590 GYK QG AV+ NV HL D A+ G + QLF +PHP Sbjct: 2916 GYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPP 2975 Query: 591 R 591 + Sbjct: 2976 K 2976 Score = 36.2 bits (82), Expect = 0.32 Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 13/102 (12%) Query: 1623 YEIGVSQQDAHFHFHQIRL-QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG 1681 +E+G S++ A + L Q+ GH+ V C + +SGS+DRT +W L Sbjct: 3105 WEMGTSKEKAK----TVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLS 3160 Query: 1682 DGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGA-VHVW 1722 T HR V + E +VSC G +HVW Sbjct: 3161 FLTQ-------LRGHRAPVSALCINELTGDIVSCAGTYIHVW 3195 >gi|154240744 neurobeachin-like 1 isoform 2 [Homo sapiens] Length = 1335 Score = 95.9 bits (237), Expect = 3e-19 Identities = 76/241 (31%), Positives = 109/241 (45%), Gaps = 29/241 (12%) Query: 348 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 400 L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL Sbjct: 713 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 772 Query: 401 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 459 K +N K K + YE G + H H S+ + Y + T Sbjct: 773 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 827 Query: 460 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 508 + R A + H PA+ + + + D E IPEF+ P + + Sbjct: 828 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 887 Query: 509 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563 + D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N Sbjct: 888 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 947 Query: 564 V 564 V Sbjct: 948 V 948 >gi|191252801 WDFY family member 4 [Homo sapiens] Length = 3184 Score = 89.7 bits (221), Expect = 2e-17 Identities = 91/305 (29%), Positives = 120/305 (39%), Gaps = 64/305 (20%) Query: 346 RSLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPHGR------FRD 398 R ++ W ISNF YLM LN AGR D +PV PWV+ D+T+ FRD Sbjct: 2536 RIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLADYTSETLNLANPKIFRD 2595 Query: 399 LRKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRT 458 L K K +++L F Q F G+ H+ + S I Y R Sbjct: 2596 LSKPMGAQTK-ERKLKFI-----QRFKEVEKTEGDMTVQCHYYTHYSSAIIVASYLVRMP 2649 Query: 459 P-RSVLCG--------------HVRAQWEPHEYPASMERMQNWTPDECIPEFYTDPSIFR 503 P C V++ WE AS E M + E PEF+ P Sbjct: 2650 PFTQAFCALQGGSFDVADRMFHSVKSTWES----ASRENMSDVR--ELTPEFFYLPEFLT 2703 Query: 504 SIH----------PDMPDLDVPAWCSSS-QEFVAAHRALLESREVSRDLHHWIDLTFGYK 552 + + + D+ +P W ++F++ HR LES VS +LHHWIDL FGYK Sbjct: 2704 NCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDLIFGYK 2763 Query: 553 LQGKEAVKEKNV-----------CLHLVDAHTHLASYGVV--------QLFDQPHPQRLA 593 QG AV N+ + D G V QLF +PHP R A Sbjct: 2764 QQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPHPARTA 2823 Query: 594 GAPAL 598 L Sbjct: 2824 AGKPL 2828 Score = 35.4 bits (80), Expect = 0.55 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 8/83 (9%) Query: 1642 QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVF 1701 Q+ GH+ AV C+A + +SGS+D T LW L + T A HR+ + Sbjct: 2976 QALYGHTQAVTCLAASVTFSLLVSGSQDCTCILWDLDHLTHVTRLPA-------HREGIS 3028 Query: 1702 FVGQLEAPQHVVSCDGA-VHVWD 1723 + + +VSC GA + +W+ Sbjct: 3029 AITISDVSGTIVSCAGAHLSLWN 3051 >gi|54292123 lysosomal trafficking regulator [Homo sapiens] Length = 3801 Score = 68.9 bits (167), Expect = 4e-11 Identities = 83/311 (26%), Positives = 122/311 (39%), Gaps = 54/311 (17%) Query: 352 WVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPHGRFRDL----RKSK--- 403 W G+I+NF YL LN+ AGR D +PV P+++ D+ + DL SK Sbjct: 3135 WYTGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILADYVSETLDLNDLLIYRNLSKPIA 3194 Query: 404 -FRLNKGDKQLDFTYEMTRQAFVAGGAGGGE-PPHVPHHISDVLSDI-TYYVYKARRTPR 460 K D+ +D TY+ + + G PP P+H S+ T + R P Sbjct: 3195 VQYKEKEDRYVD-TYKYLEEEYRKGAREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPF 3253 Query: 461 SVLCGHVRAQWEPHEYPASMERMQNWT-----------PDECIPEFYTDPSIF------- 502 + + + Q + + P N T E IPEF+ P Sbjct: 3254 TKM--FLAYQDQSFDIPDRTFHSTNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFD 3311 Query: 503 ---RSIHPDMPDLDVPAWCSSSQE-FVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEA 558 R + +++P W + F+ HR LES VS+++ WIDL FGYK +GK + Sbjct: 3312 FGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESDYVSQNICQWIDLVFGYKQKGKAS 3371 Query: 559 VKEKNVC----------------LHLVDAHTHLASYGVV--QLFDQPHPQRLAGAPALAP 600 V+ NV + T + +YG QLF H R + Sbjct: 3372 VQAINVFHPATYFGMDVSAVEDPVQRRALETMIKTYGQTPRQLFHMAHVSRPGAKLNIEG 3431 Query: 601 EPPLIPKLLVQ 611 E P LLVQ Sbjct: 3432 ELPAAVGLLVQ 3442 >gi|89886480 zinedin isoform 2 [Homo sapiens] Length = 760 Score = 62.4 bits (150), Expect = 4e-09 Identities = 65/260 (25%), Positives = 102/260 (39%), Gaps = 21/260 (8%) Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG----DGTSETAPRLVYTQH 1696 + +F H G V VA S+ ++ SG D + W + + DG + V H Sbjct: 491 IHAFRAHRGPVLAVAMGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGH 550 Query: 1697 RKSVFFVGQLEAPQHVVSC--DGAVHVWDPFTGK-----TLRTVEPLDSRVPLTAVAVMP 1749 +V+ + Q + SC DG V +WDP + T T + + P Sbjct: 551 GDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAFTSTEP 610 Query: 1750 APHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGF 1809 A H + S D+ L ++ L E R G P + + P+ + Sbjct: 611 A-HIVASFRSGDTVLYDMEVGSALLTLESR--GSSGPTQINQVVSHPNQPLTITAHDDRG 667 Query: 1810 MVLLDTRTGLVLRGWPAHEGDILQIKAVE--GSVLVSSSSDHSLTVW----KELEQKPTH 1863 + LD RTG + AH D + AV+ G+ L+S S D SL +W K Q+ T Sbjct: 668 IRFLDNRTGKPVHSMVAHL-DAVTCLAVDPNGAFLMSGSHDCSLRLWSLDNKTCVQEITA 726 Query: 1864 HYKSASDPIHTFDLYGSEVV 1883 H K + IH + S+ + Sbjct: 727 HRKKHEEAIHAVACHPSKAL 746 >gi|89886477 zinedin isoform 1 [Homo sapiens] Length = 753 Score = 62.4 bits (150), Expect = 4e-09 Identities = 65/260 (25%), Positives = 102/260 (39%), Gaps = 21/260 (8%) Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG----DGTSETAPRLVYTQH 1696 + +F H G V VA S+ ++ SG D + W + + DG + V H Sbjct: 484 IHAFRAHRGPVLAVAMGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGH 543 Query: 1697 RKSVFFVGQLEAPQHVVSC--DGAVHVWDPFTGK-----TLRTVEPLDSRVPLTAVAVMP 1749 +V+ + Q + SC DG V +WDP + T T + + P Sbjct: 544 GDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAFTSTEP 603 Query: 1750 APHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGF 1809 A H + S D+ L ++ L E R G P + + P+ + Sbjct: 604 A-HIVASFRSGDTVLYDMEVGSALLTLESR--GSSGPTQINQVVSHPNQPLTITAHDDRG 660 Query: 1810 MVLLDTRTGLVLRGWPAHEGDILQIKAVE--GSVLVSSSSDHSLTVW----KELEQKPTH 1863 + LD RTG + AH D + AV+ G+ L+S S D SL +W K Q+ T Sbjct: 661 IRFLDNRTGKPVHSMVAHL-DAVTCLAVDPNGAFLMSGSHDCSLRLWSLDNKTCVQEITA 719 Query: 1864 HYKSASDPIHTFDLYGSEVV 1883 H K + IH + S+ + Sbjct: 720 HRKKHEEAIHAVACHPSKAL 739 >gi|26665869 WD repeat domain 51B [Homo sapiens] Length = 478 Score = 60.8 bits (146), Expect = 1e-08 Identities = 71/309 (22%), Positives = 122/309 (39%), Gaps = 42/309 (13%) Query: 1640 RLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKS 1699 + F H+ V+ V + F + S+D+++++W +Y R +Y+ +R + Sbjct: 94 KFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQ---------RFLYSLYRHT 144 Query: 1700 VFFVGQLEAPQH--VVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755 + +P +VSC D + +WD T K + V V T I Sbjct: 145 HWVRCAKFSPDGRLIVSCSEDKTIKIWDT-TNK--QCVNNFSDSVGFANFVDFNPSGTCI 201 Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815 A SD T++ D R L +++ + G V ++ PSG ++ S G + +LD Sbjct: 202 ASAGSDQTVKVWDVRVNKLLQHYQV----HSGGVNCISFHPSGNYLITASSDGTLKILDL 257 Query: 1816 RTGLVLRGWPAHEGDILQIKAVEGSVL-VSSSSDHSLTVWK----ELEQK-------PTH 1863 G ++ H G + + +G L S +D + +W+ EL K Sbjct: 258 LEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDELHCKGLTKRNLKRL 317 Query: 1864 HYKSASDPIHTFDLY-------GSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTL 1916 H+ S P H D+Y +V T ++ K+ V L LS ++ T Sbjct: 318 HFDS---PPHLLDIYPRTPHPHEEKVETVEINPKLEVIDLQISTPPVMDILSFDSTTTTE 374 Query: 1917 TSLALLPTK 1925 TS LP K Sbjct: 375 TSGRTLPDK 383 >gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] Length = 369 Score = 58.9 bits (141), Expect = 5e-08 Identities = 61/224 (27%), Positives = 88/224 (39%), Gaps = 17/224 (7%) Query: 1638 QIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHR 1697 Q R F GH AV CV S SGS+D+TVR+W G+ T V+ H Sbjct: 13 QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST-------VFRAHT 65 Query: 1698 KSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755 +V V Q V S D V VW K L + L + A I Sbjct: 66 ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFS---LSQHINWVRCAKFSPDGRLI 122 Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815 AS D T++ D H + G G V + PSG + A + + D Sbjct: 123 VSASDDKTVKLWDKSSRECVHSYCEHG----GFVTYVDFHPSGTCIAAAGMDNTVKVWDV 178 Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELE 1858 RT +L+ + H + + G+ L+++SSD +L + +E Sbjct: 179 RTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLME 222 >gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] Length = 359 Score = 58.9 bits (141), Expect = 5e-08 Identities = 61/224 (27%), Positives = 88/224 (39%), Gaps = 17/224 (7%) Query: 1638 QIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHR 1697 Q R F GH AV CV S SGS+D+TVR+W G+ T V+ H Sbjct: 51 QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST-------VFRAHT 103 Query: 1698 KSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755 +V V Q V S D V VW K L + L + A I Sbjct: 104 ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFS---LSQHINWVRCAKFSPDGRLI 160 Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815 AS D T++ D H + G G V + PSG + A + + D Sbjct: 161 VSASDDKTVKLWDKSSRECVHSYCEHG----GFVTYVDFHPSGTCIAAAGMDNTVKVWDV 216 Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELE 1858 RT +L+ + H + + G+ L+++SSD +L + +E Sbjct: 217 RTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLME 260 Score = 43.1 bits (100), Expect = 0.003 Identities = 57/266 (21%), Positives = 104/266 (39%), Gaps = 31/266 (11%) Query: 1644 FPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVFFV 1703 F GH AV CV + SGS D + +W + + +T H+ +V V Sbjct: 15 FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHM-------KPQSRAYRFTGHKDAVTCV 67 Query: 1704 GQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPH-----TSI 1755 H++ S D V +W P +S V A + + H S Sbjct: 68 -NFSPSGHLLASGSRDKTVRIWVPNVKG--------ESTVFRAHTATVRSVHFCSDGQSF 118 Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815 AS D T++ + + F L +N VR SP GR +V+ + L D Sbjct: 119 VTASDDKTVKVWATHRQ--KFLFSLSQHIN--WVRCAKFSPDGRLIVSASDDKTVKLWDK 174 Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELEQKPTHHYKSASDPIH- 1873 + + + H G + + G+ + ++ D+++ VW + HY+ S ++ Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 234 Query: 1874 -TFDLYGSEVVTGTVSNKIGVCSLLE 1898 +F G+ ++T + + + + L+E Sbjct: 235 LSFHPSGNYLITASSDSTLKILDLME 260 >gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] Length = 407 Score = 58.9 bits (141), Expect = 5e-08 Identities = 61/224 (27%), Positives = 88/224 (39%), Gaps = 17/224 (7%) Query: 1638 QIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHR 1697 Q R F GH AV CV S SGS+D+TVR+W G+ T V+ H Sbjct: 51 QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST-------VFRAHT 103 Query: 1698 KSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755 +V V Q V S D V VW K L + L + A I Sbjct: 104 ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFS---LSQHINWVRCAKFSPDGRLI 160 Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815 AS D T++ D H + G G V + PSG + A + + D Sbjct: 161 VSASDDKTVKLWDKSSRECVHSYCEHG----GFVTYVDFHPSGTCIAAAGMDNTVKVWDV 216 Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELE 1858 RT +L+ + H + + G+ L+++SSD +L + +E Sbjct: 217 RTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLME 260 Score = 43.1 bits (100), Expect = 0.003 Identities = 57/266 (21%), Positives = 104/266 (39%), Gaps = 31/266 (11%) Query: 1644 FPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVFFV 1703 F GH AV CV + SGS D + +W + + +T H+ +V V Sbjct: 15 FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHM-------KPQSRAYRFTGHKDAVTCV 67 Query: 1704 GQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPH-----TSI 1755 H++ S D V +W P +S V A + + H S Sbjct: 68 -NFSPSGHLLASGSRDKTVRIWVPNVKG--------ESTVFRAHTATVRSVHFCSDGQSF 118 Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815 AS D T++ + + F L +N VR SP GR +V+ + L D Sbjct: 119 VTASDDKTVKVWATHRQ--KFLFSLSQHIN--WVRCAKFSPDGRLIVSASDDKTVKLWDK 174 Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELEQKPTHHYKSASDPIH- 1873 + + + H G + + G+ + ++ D+++ VW + HY+ S ++ Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 234 Query: 1874 -TFDLYGSEVVTGTVSNKIGVCSLLE 1898 +F G+ ++T + + + + L+E Sbjct: 235 LSFHPSGNYLITASSDSTLKILDLME 260 >gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens] Length = 919 Score = 55.8 bits (133), Expect = 4e-07 Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 14/223 (6%) Query: 1639 IRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1698 +R + H G++ CVA +GS D+ V++ P + + T P L ++ H Sbjct: 652 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPF--NAETCNATGPDLEFSMHDG 709 Query: 1699 SVFFVGQLEAPQH----VVSC---DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAP 1751 ++ + +E P+ ++S D ++ D G+ L + + +A+ Sbjct: 710 TIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI----LALYTWS 765 Query: 1752 HTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMV 1811 I S D T+RF D R P V ++A+ PSGR + G + Sbjct: 766 GWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCM 825 Query: 1812 LLDTRTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTV 1853 L D R G +++ + H D+ ++ G+ L++ S D + V Sbjct: 826 LYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 868 >gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens] Length = 927 Score = 55.8 bits (133), Expect = 4e-07 Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 14/223 (6%) Query: 1639 IRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1698 +R + H G++ CVA +GS D+ V++ P + + T P L ++ H Sbjct: 660 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPF--NAETCNATGPDLEFSMHDG 717 Query: 1699 SVFFVGQLEAPQH----VVSC---DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAP 1751 ++ + +E P+ ++S D ++ D G+ L + + +A+ Sbjct: 718 TIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI----LALYTWS 773 Query: 1752 HTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMV 1811 I S D T+RF D R P V ++A+ PSGR + G + Sbjct: 774 GWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCM 833 Query: 1812 LLDTRTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTV 1853 L D R G +++ + H D+ ++ G+ L++ S D + V Sbjct: 834 LYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 876 >gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens] Length = 920 Score = 55.8 bits (133), Expect = 4e-07 Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 14/223 (6%) Query: 1639 IRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1698 +R + H G++ CVA +GS D+ V++ P + + T P L ++ H Sbjct: 653 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPF--NAETCNATGPDLEFSMHDG 710 Query: 1699 SVFFVGQLEAPQH----VVSC---DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAP 1751 ++ + +E P+ ++S D ++ D G+ L + + +A+ Sbjct: 711 TIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI----LALYTWS 766 Query: 1752 HTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMV 1811 I S D T+RF D R P V ++A+ PSGR + G + Sbjct: 767 GWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCM 826 Query: 1812 LLDTRTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTV 1853 L D R G +++ + H D+ ++ G+ L++ S D + V Sbjct: 827 LYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 869 >gi|21071067 TBP-associated factor 5 [Homo sapiens] Length = 800 Score = 52.0 bits (123), Expect = 6e-06 Identities = 64/253 (25%), Positives = 107/253 (42%), Gaps = 25/253 (9%) Query: 1646 GHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLV-YTQHRKSVFFVG 1704 GHSG V + ++ LS S+D TVRLW L +T LV Y H V+ Sbjct: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL--------QTFTCLVGYKGHNYPVWDTQ 592 Query: 1705 QLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTS-ITMASSD 1761 + VS D +W + LR + V T P+++ + S+D Sbjct: 593 FSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFH----PNSNYVATGSAD 648 Query: 1762 STLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTGLVL 1821 T+R D F + G + +L SP+GR + G + G ++L D GL++ Sbjct: 649 RTVRLWDVLNGNCVRIFTG----HKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMV 704 Query: 1822 RGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVW---KELEQKPTHHYKSASDPIHTFDL 1877 H + ++ + +G +L S S D+++ +W K E T + +A+ I+ + Sbjct: 705 GELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPE- 763 Query: 1878 YGSEVVTGTVSNK 1890 E++ GT K Sbjct: 764 NSQELLLGTYMTK 776 Score = 36.6 bits (83), Expect = 0.25 Identities = 17/45 (37%), Positives = 25/45 (55%), Gaps = 2/45 (4%) Query: 1635 HFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYN 1679 H+ +R+ F GH V C + ++ +GS DRTVRLW + N Sbjct: 616 HYQPLRI--FAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658 >gi|38569484 kinesin family member 21A [Homo sapiens] Length = 1661 Score = 51.2 bits (121), Expect = 1e-05 Identities = 56/236 (23%), Positives = 95/236 (40%), Gaps = 28/236 (11%) Query: 1646 GHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGD-----GTSETAPRLVYTQHRKSV 1700 GH+ AV CV S++D +GSKDRT ++W L + G + Y + V Sbjct: 1332 GHTKAVLCVD--STDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLV 1389 Query: 1701 FFVGQLEAPQ----------HVVSCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPA 1750 F V ++ G V + D + T RTV + +A+ P Sbjct: 1390 FTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQINQIALNPT 1449 Query: 1751 PHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS-VVAGFSSGF 1809 + A+S + +R D ++ Q +L G L P + + SG+ ++ G + Sbjct: 1450 --GTFLYAASGNAVRMWDLKR--FQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDHY 1505 Query: 1810 MVLLDTRTGLVLRGWPAH-----EGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860 + + D G + P H D ++ ++G L S S D+ + W +L QK Sbjct: 1506 IKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKW-DLTQK 1560 >gi|83779014 katanin p80 subunit B 1 [Homo sapiens] Length = 655 Score = 49.3 bits (116), Expect = 4e-05 Identities = 52/220 (23%), Positives = 91/220 (41%), Gaps = 20/220 (9%) Query: 1640 RLQSFPGHSGAVKC-VAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1698 +LQ H+ V V +S +G D V LW + S T +T + Sbjct: 12 KLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTG----HTSPVE 67 Query: 1699 SVFFVGQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755 SV +L P+ ++ S G++ VWD K LRT+ + + + ++ P + Sbjct: 68 SV----RLNTPEELIVAGSQSGSIRVWDLEAAKILRTL--MGHKANICSLDFHPYGEF-V 120 Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815 S D+ ++ D R+ G +R + VR L SP G+ + + + L D Sbjct: 121 ASGSQDTNIKLWDIRRKGCVFRYRG----HSQAVRCLRFSPDGKWLASAADDHTVKLWDL 176 Query: 1816 RTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTVW 1854 G ++ +P H G + ++ +L S SSD ++ W Sbjct: 177 TAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFW 216 Score = 38.5 bits (88), Expect = 0.065 Identities = 17/40 (42%), Positives = 22/40 (55%) Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680 + FPGH+G V V +E SGS DRT+R W L + Sbjct: 182 MSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKF 221 >gi|16554629 WD repeat domain 5 [Homo sapiens] Length = 334 Score = 48.5 bits (114), Expect = 6e-05 Identities = 57/239 (23%), Positives = 98/239 (41%), Gaps = 35/239 (14%) Query: 1642 QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVF 1701 ++ GH + VA S + +S S D+T+++W + + L + + Sbjct: 81 KTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV--------SSGKCLKTLKGHSNYV 132 Query: 1702 FVGQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 1758 F +++ S D +V +WD TGK L+T+ P S P++AV + I + Sbjct: 133 FCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL-PAHSD-PVSAVH-FNRDGSLIVSS 189 Query: 1759 SSDSTLRFVD-----CRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLL 1813 S D R D C K + + NP V + SP+G+ ++A + L Sbjct: 190 SYDGLCRIWDTASGQCLKTLIDDD-------NPP-VSFVKFSPNGKYILAATLDNTLKLW 241 Query: 1814 DTRTGLVLRGWPAHEGD----ILQIKAVEGSVLVSSSSDHSLTVW----KELEQKPTHH 1864 D G L+ + H+ + G +VS S D+ + +W KE+ QK H Sbjct: 242 DYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH 300 Score = 40.0 bits (92), Expect = 0.022 Identities = 50/220 (22%), Positives = 91/220 (41%), Gaps = 15/220 (6%) Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSV 1700 L++ GHS V C + +SGS D +VR+W + +T P H V Sbjct: 122 LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT--GKCLKTLP-----AHSDPV 174 Query: 1701 FFVGQLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 1758 V +VS DG +WD +G+ L+T+ D P++ V P I A Sbjct: 175 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID-DDNPPVSFVKFSP-NGKYILAA 232 Query: 1759 SSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTG 1818 + D+TL+ D K G + G + A G+ +V+G + + + +T Sbjct: 233 TLDNTLKLWDYSK-GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTK 291 Query: 1819 LVLRGWPAHEGDILQIKAVEGSVLVSSS---SDHSLTVWK 1855 +++ H ++ +++S+ +D ++ +WK Sbjct: 292 EIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331 >gi|16554627 WD repeat domain 5 [Homo sapiens] Length = 334 Score = 48.5 bits (114), Expect = 6e-05 Identities = 57/239 (23%), Positives = 98/239 (41%), Gaps = 35/239 (14%) Query: 1642 QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVF 1701 ++ GH + VA S + +S S D+T+++W + + L + + Sbjct: 81 KTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV--------SSGKCLKTLKGHSNYV 132 Query: 1702 FVGQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 1758 F +++ S D +V +WD TGK L+T+ P S P++AV + I + Sbjct: 133 FCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL-PAHSD-PVSAVH-FNRDGSLIVSS 189 Query: 1759 SSDSTLRFVD-----CRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLL 1813 S D R D C K + + NP V + SP+G+ ++A + L Sbjct: 190 SYDGLCRIWDTASGQCLKTLIDDD-------NPP-VSFVKFSPNGKYILAATLDNTLKLW 241 Query: 1814 DTRTGLVLRGWPAHEGD----ILQIKAVEGSVLVSSSSDHSLTVW----KELEQKPTHH 1864 D G L+ + H+ + G +VS S D+ + +W KE+ QK H Sbjct: 242 DYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH 300 Score = 40.0 bits (92), Expect = 0.022 Identities = 50/220 (22%), Positives = 91/220 (41%), Gaps = 15/220 (6%) Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSV 1700 L++ GHS V C + +SGS D +VR+W + +T P H V Sbjct: 122 LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT--GKCLKTLP-----AHSDPV 174 Query: 1701 FFVGQLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 1758 V +VS DG +WD +G+ L+T+ D P++ V P I A Sbjct: 175 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID-DDNPPVSFVKFSP-NGKYILAA 232 Query: 1759 SSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTG 1818 + D+TL+ D K G + G + A G+ +V+G + + + +T Sbjct: 233 TLDNTLKLWDYSK-GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTK 291 Query: 1819 LVLRGWPAHEGDILQIKAVEGSVLVSSS---SDHSLTVWK 1855 +++ H ++ +++S+ +D ++ +WK Sbjct: 292 EIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331 >gi|166795264 AE binding protein 2 isoform b [Homo sapiens] Length = 517 Score = 48.5 bits (114), Expect = 6e-05 Identities = 44/146 (30%), Positives = 64/146 (43%), Gaps = 12/146 (8%) Query: 1064 LPDYTSGVSFHDQADLPETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEER 1123 LP + G + +A+ PE E+ + E + EAEAV+ L+ S G Sbjct: 20 LPPGSPGSAARGRAEPPEEEEEEE-----EEEEEAEAEAVAALLLNGGSGGG----GGGG 70 Query: 1124 APDEGGAPVDKSSLRSGDSSQDLKQSEGSEE---EEEEEDSCVVLEEEEGEQEEVTGASE 1180 GG + S S +S+ + E EE EEE+E S EEE E + G+S Sbjct: 71 GGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSG 130 Query: 1181 LTLSDTVLSMETVVAGGSGGDGEEEE 1206 + SD S+ A S GDG+ +E Sbjct: 131 GSSSDETRSLSPGAASSSSGDGDGKE 156 >gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens] Length = 234 Score = 48.5 bits (114), Expect = 6e-05 Identities = 31/81 (38%), Positives = 43/81 (53%), Gaps = 6/81 (7%) Query: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200 D + L E E EEE ++ V+E+EEGE+EE G E D E G + G Sbjct: 158 DHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEE----DVSGGDEEDEEGYNDG 213 Query: 1201 --DGEEEEEALPEQSEGKEQK 1219 DGEE+EE L E+ G+++K Sbjct: 214 EVDGEEDEEELGEEERGQKRK 234 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.135 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 85,716,414 Number of Sequences: 37866 Number of extensions: 4590288 Number of successful extensions: 26994 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 151 Number of HSP's successfully gapped in prelim test: 369 Number of HSP's that attempted gapping in prelim test: 21144 Number of HSP's gapped (non-prelim): 3345 length of query: 1941 length of database: 18,247,518 effective HSP length: 117 effective length of query: 1824 effective length of database: 13,817,196 effective search space: 25202565504 effective search space used: 25202565504 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.