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Search of human proteins with 239756473
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239756473 PREDICTED: transmembrane protein 114 [Homo
sapiens]
(223 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens] 433 e-122
gi|226437592 transmembrane protein 114 [Homo sapiens] 433 e-122
gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo... 419 e-117
gi|239745400 PREDICTED: transmembrane protein 114 [Homo sapiens] 233 1e-61
gi|93588650 claudin domain containing 1 protein isoform a [Homo ... 57 1e-08
gi|93588620 claudin domain containing 1 protein isoform b [Homo ... 57 1e-08
gi|93588614 claudin domain containing 1 protein isoform a [Homo ... 57 1e-08
gi|93588624 claudin domain containing 1 protein isoform a [Homo ... 57 1e-08
gi|11096340 claudin domain containing 1 protein isoform a [Homo ... 57 1e-08
gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H... 57 1e-08
gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Ho... 57 2e-08
gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Ho... 56 2e-08
gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Ho... 55 5e-08
gi|93588657 claudin domain containing 1 protein isoform d [Homo ... 51 7e-07
gi|22027551 voltage-dependent calcium channel gamma-5 subunit is... 49 3e-06
gi|7656950 voltage-dependent calcium channel gamma-5 subunit iso... 49 3e-06
gi|21361975 voltage-dependent calcium channel gamma-7 subunit [H... 41 0.001
gi|22748835 transmembrane protein 178 [Homo sapiens] 39 0.005
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 36 0.023
gi|5031949 natural killer cell group 7 sequence [Homo sapiens] 35 0.039
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 35 0.051
gi|71999143 opsin 4 isoform 2 [Homo sapiens] 34 0.088
gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ... 34 0.11
gi|4503561 epithelial membrane protein 2 [Homo sapiens] 34 0.11
gi|169171558 PREDICTED: hypothetical protein [Homo sapiens] 32 0.33
gi|169171977 PREDICTED: hypothetical protein [Homo sapiens] 32 0.33
gi|169171016 PREDICTED: hypothetical protein [Homo sapiens] 32 0.33
gi|239509059 PREDICTED: hypothetical protein [Homo sapiens] 32 0.33
gi|4503563 epithelial membrane protein 3 [Homo sapiens] 32 0.57
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 31 0.74
>gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]
Length = 223
Score = 433 bits (1113), Expect = e-122
Identities = 223/223 (100%), Positives = 223/223 (100%)
Query: 1 MRVHLGGLAGAAALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPE 60
MRVHLGGLAGAAALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPE
Sbjct: 1 MRVHLGGLAGAAALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPE 60
Query: 61 PLSSHSGLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFG 120
PLSSHSGLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFG
Sbjct: 61 PLSSHSGLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFG 120
Query: 121 GMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQ 180
GMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQ
Sbjct: 121 GMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQ 180
Query: 181 VDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI 223
VDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI
Sbjct: 181 VDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI 223
>gi|226437592 transmembrane protein 114 [Homo sapiens]
Length = 223
Score = 433 bits (1113), Expect = e-122
Identities = 223/223 (100%), Positives = 223/223 (100%)
Query: 1 MRVHLGGLAGAAALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPE 60
MRVHLGGLAGAAALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPE
Sbjct: 1 MRVHLGGLAGAAALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPE 60
Query: 61 PLSSHSGLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFG 120
PLSSHSGLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFG
Sbjct: 61 PLSSHSGLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFG 120
Query: 121 GMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQ 180
GMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQ
Sbjct: 121 GMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQ 180
Query: 181 VDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI 223
VDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI
Sbjct: 181 VDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI 223
>gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo
sapiens]
Length = 217
Score = 419 bits (1077), Expect = e-117
Identities = 216/217 (99%), Positives = 217/217 (100%)
Query: 7 GLAGAAALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHS 66
GLAGAAALTGALSFVLLAAAIGT+FWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHS
Sbjct: 1 GLAGAAALTGALSFVLLAAAIGTEFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHS 60
Query: 67 GLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFL 126
GLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFL
Sbjct: 61 GLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFL 120
Query: 127 SFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFG 186
SFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFG
Sbjct: 121 SFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFG 180
Query: 187 WSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI 223
WSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI
Sbjct: 181 WSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI 217
>gi|239745400 PREDICTED: transmembrane protein 114 [Homo sapiens]
Length = 122
Score = 233 bits (593), Expect = 1e-61
Identities = 122/122 (100%), Positives = 122/122 (100%)
Query: 102 MHGTFVILLPLSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYS 161
MHGTFVILLPLSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYS
Sbjct: 1 MHGTFVILLPLSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYS 60
Query: 162 AAAFREALCLLEEKALLDQVDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQ 221
AAAFREALCLLEEKALLDQVDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQ
Sbjct: 61 AAAFREALCLLEEKALLDQVDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQ 120
Query: 222 AI 223
AI
Sbjct: 121 AI 122
>gi|93588650 claudin domain containing 1 protein isoform a [Homo
sapiens]
Length = 253
Score = 57.4 bits (137), Expect = 1e-08
Identities = 65/238 (27%), Positives = 99/238 (41%), Gaps = 51/238 (21%)
Query: 12 AALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSI----------NRSQPEP 61
A + +S + +AA+IGTDFWY E + DL SI ++ +
Sbjct: 12 ACVLSLISTIYMAASIGTDFWY----EYRSPVQENSSDLNKSIWDEFISDEADEKTYNDA 67
Query: 62 LSSHSG---LWRTC-RVQSPCTPLMNPFRLENV---------TVSESSRQLLTMHG---- 104
L ++G LWR C + P R E+ T++E + G
Sbjct: 68 LFRYNGTVGLWRRCITIPKNMHWYSPPERTESFDVVTKCVSFTLTEQFMEKFVDPGNHNS 127
Query: 105 ------TFV----ILLP-LSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAG 153
T++ LLP +SL LM FG + G + + ++ + TGIL L + TL
Sbjct: 128 GIDLLRTYLWRCQFLLPFVSLGLMCFGALIGLCACICRSLYPTIATGILHLLAGLCTLGS 187
Query: 154 ISVYIAYSAAAFREALCLLEEK-ALLDQVDISFGWSLALGWISFIAELLTGAAFLAAA 210
+S Y+A + LL +K L D V FGWS L +S + + A F+ AA
Sbjct: 188 VSCYVA--------GIELLHQKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAA 237
>gi|93588620 claudin domain containing 1 protein isoform b [Homo
sapiens]
Length = 276
Score = 57.4 bits (137), Expect = 1e-08
Identities = 65/238 (27%), Positives = 99/238 (41%), Gaps = 51/238 (21%)
Query: 12 AALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSI----------NRSQPEP 61
A + +S + +AA+IGTDFWY E + DL SI ++ +
Sbjct: 35 ACVLSLISTIYMAASIGTDFWY----EYRSPVQENSSDLNKSIWDEFISDEADEKTYNDA 90
Query: 62 LSSHSG---LWRTC-RVQSPCTPLMNPFRLENV---------TVSESSRQLLTMHG---- 104
L ++G LWR C + P R E+ T++E + G
Sbjct: 91 LFRYNGTVGLWRRCITIPKNMHWYSPPERTESFDVVTKCVSFTLTEQFMEKFVDPGNHNS 150
Query: 105 ------TFV----ILLP-LSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAG 153
T++ LLP +SL LM FG + G + + ++ + TGIL L + TL
Sbjct: 151 GIDLLRTYLWRCQFLLPFVSLGLMCFGALIGLCACICRSLYPTIATGILHLLAGLCTLGS 210
Query: 154 ISVYIAYSAAAFREALCLLEEK-ALLDQVDISFGWSLALGWISFIAELLTGAAFLAAA 210
+S Y+A + LL +K L D V FGWS L +S + + A F+ AA
Sbjct: 211 VSCYVA--------GIELLHQKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAA 260
>gi|93588614 claudin domain containing 1 protein isoform a [Homo
sapiens]
Length = 253
Score = 57.4 bits (137), Expect = 1e-08
Identities = 65/238 (27%), Positives = 99/238 (41%), Gaps = 51/238 (21%)
Query: 12 AALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSI----------NRSQPEP 61
A + +S + +AA+IGTDFWY E + DL SI ++ +
Sbjct: 12 ACVLSLISTIYMAASIGTDFWY----EYRSPVQENSSDLNKSIWDEFISDEADEKTYNDA 67
Query: 62 LSSHSG---LWRTC-RVQSPCTPLMNPFRLENV---------TVSESSRQLLTMHG---- 104
L ++G LWR C + P R E+ T++E + G
Sbjct: 68 LFRYNGTVGLWRRCITIPKNMHWYSPPERTESFDVVTKCVSFTLTEQFMEKFVDPGNHNS 127
Query: 105 ------TFV----ILLP-LSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAG 153
T++ LLP +SL LM FG + G + + ++ + TGIL L + TL
Sbjct: 128 GIDLLRTYLWRCQFLLPFVSLGLMCFGALIGLCACICRSLYPTIATGILHLLAGLCTLGS 187
Query: 154 ISVYIAYSAAAFREALCLLEEK-ALLDQVDISFGWSLALGWISFIAELLTGAAFLAAA 210
+S Y+A + LL +K L D V FGWS L +S + + A F+ AA
Sbjct: 188 VSCYVA--------GIELLHQKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAA 237
>gi|93588624 claudin domain containing 1 protein isoform a [Homo
sapiens]
Length = 253
Score = 57.4 bits (137), Expect = 1e-08
Identities = 65/238 (27%), Positives = 99/238 (41%), Gaps = 51/238 (21%)
Query: 12 AALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSI----------NRSQPEP 61
A + +S + +AA+IGTDFWY E + DL SI ++ +
Sbjct: 12 ACVLSLISTIYMAASIGTDFWY----EYRSPVQENSSDLNKSIWDEFISDEADEKTYNDA 67
Query: 62 LSSHSG---LWRTC-RVQSPCTPLMNPFRLENV---------TVSESSRQLLTMHG---- 104
L ++G LWR C + P R E+ T++E + G
Sbjct: 68 LFRYNGTVGLWRRCITIPKNMHWYSPPERTESFDVVTKCVSFTLTEQFMEKFVDPGNHNS 127
Query: 105 ------TFV----ILLP-LSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAG 153
T++ LLP +SL LM FG + G + + ++ + TGIL L + TL
Sbjct: 128 GIDLLRTYLWRCQFLLPFVSLGLMCFGALIGLCACICRSLYPTIATGILHLLAGLCTLGS 187
Query: 154 ISVYIAYSAAAFREALCLLEEK-ALLDQVDISFGWSLALGWISFIAELLTGAAFLAAA 210
+S Y+A + LL +K L D V FGWS L +S + + A F+ AA
Sbjct: 188 VSCYVA--------GIELLHQKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAA 237
>gi|11096340 claudin domain containing 1 protein isoform a [Homo
sapiens]
Length = 253
Score = 57.4 bits (137), Expect = 1e-08
Identities = 65/238 (27%), Positives = 99/238 (41%), Gaps = 51/238 (21%)
Query: 12 AALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSI----------NRSQPEP 61
A + +S + +AA+IGTDFWY E + DL SI ++ +
Sbjct: 12 ACVLSLISTIYMAASIGTDFWY----EYRSPVQENSSDLNKSIWDEFISDEADEKTYNDA 67
Query: 62 LSSHSG---LWRTC-RVQSPCTPLMNPFRLENV---------TVSESSRQLLTMHG---- 104
L ++G LWR C + P R E+ T++E + G
Sbjct: 68 LFRYNGTVGLWRRCITIPKNMHWYSPPERTESFDVVTKCVSFTLTEQFMEKFVDPGNHNS 127
Query: 105 ------TFV----ILLP-LSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAG 153
T++ LLP +SL LM FG + G + + ++ + TGIL L + TL
Sbjct: 128 GIDLLRTYLWRCQFLLPFVSLGLMCFGALIGLCACICRSLYPTIATGILHLLAGLCTLGS 187
Query: 154 ISVYIAYSAAAFREALCLLEEK-ALLDQVDISFGWSLALGWISFIAELLTGAAFLAAA 210
+S Y+A + LL +K L D V FGWS L +S + + A F+ AA
Sbjct: 188 VSCYVA--------GIELLHQKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAA 237
>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
sapiens]
Length = 425
Score = 57.4 bits (137), Expect = 1e-08
Identities = 62/218 (28%), Positives = 96/218 (44%), Gaps = 23/218 (10%)
Query: 19 SFVLLAAAIGTDFWY-----IIDTERLERTGPGAQDLLGSINRSQPEPLS--SHSGLWRT 71
+F L+ AI TD+W I +T L G G S+ + +HSGLWR
Sbjct: 31 AFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGASEKKDPGGLTHSGLWRI 90
Query: 72 CRVQS----PCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 127
C ++ C + N F + +S+ LL + I LS IL++ GG+ S
Sbjct: 91 CCLEGLKRGVCVKI-NHFPEDTDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAAS 149
Query: 128 FLLQAYLLLLL-TGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFG 186
+ ++ ++L GILF+ + + G+ VYI SA A EEK + S+G
Sbjct: 150 RVYKSKRNIILGAGILFVAAGLSNIIGVIVYI--SANAGEPGPKRDEEK----KNHYSYG 203
Query: 187 WSLALGWISFIAELLTGA----AFLAAARELSLRRRQD 220
WS G +SFI + G ++ +RE + R D
Sbjct: 204 WSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSD 241
>gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Homo
sapiens]
Length = 323
Score = 56.6 bits (135), Expect = 2e-08
Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 18/189 (9%)
Query: 19 SFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTCRVQSPC 78
+F L+ A+GTD+W + + + +T +++ N E + +HSGLWRTC ++
Sbjct: 20 AFSLMTIAVGTDYW--LYSRGVCKTKSVSENETSKKN----EEVMTHSGLWRTCCLEGNF 73
Query: 79 TPL---MNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS-FLLQAYL 134
L ++ F + ++++ L I LS+IL+ GG+ S F +
Sbjct: 74 KGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHN 133
Query: 135 LLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWI 194
++L GI F+ + + GI VYI+ +A K+ + S+GWS G +
Sbjct: 134 IILSAGIFFVSAGLSNIIGIIVYISANAGD--------PSKSDSKKNSYSYGWSFYFGAL 185
Query: 195 SFIAELLTG 203
SFI + G
Sbjct: 186 SFIIAEMVG 194
>gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Homo
sapiens]
Length = 327
Score = 56.2 bits (134), Expect = 2e-08
Identities = 61/230 (26%), Positives = 98/230 (42%), Gaps = 32/230 (13%)
Query: 7 GLAGAAALTGALS-FVLLAAAIGTDFWYIIDTERLERT------GPGAQDLLGSINRSQP 59
GL GA + F L+A AIGTD+W T GP + G +
Sbjct: 7 GLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDL----- 61
Query: 60 EPLSSHSGLWRTCRVQ----SPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLI 115
+HSGLWR C ++ C + N F +N +SS LL + + LS I
Sbjct: 62 ----THSGLWRVCCIEGIYKGHCFRI-NHFPEDNDYDHDSSEYLLRIVRASSVFPILSTI 116
Query: 116 LMVFGGM-TGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEE 174
L++ GG+ G + ++L GILF+ + + GI VYI+ + + E+
Sbjct: 117 LLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRD--ED 174
Query: 175 KALLDQVDISFGWSLALGWISFIAELLTGA----AFLAAARELSLRRRQD 220
K + ++GWS G +SFI G ++ +EL + +++
Sbjct: 175 K----KNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKRE 220
>gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Homo
sapiens]
Length = 315
Score = 55.1 bits (131), Expect = 5e-08
Identities = 54/208 (25%), Positives = 92/208 (44%), Gaps = 20/208 (9%)
Query: 1 MRVHLGGLAGAAALTGALS-FVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQP 59
MR+ G+ GA + F L+ A+GTD+W + + + RT + + N
Sbjct: 1 MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYW--LYSRGVCRTKSTSDNETSRKN---- 54
Query: 60 EPLSSHSGLWRTCRVQSPCTPL---MNPFRLENVTVSESSRQLLTMHGTFVILLPLSLIL 116
E + +HSGLWRTC ++ + ++ F + +++ LL + LS+ L
Sbjct: 55 EEVMTHSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTL 114
Query: 117 MVFGGMTGFLS-FLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEK 175
+ FGG+ S F + ++L GI F+ + + GI VYI+ +A +
Sbjct: 115 LFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAG---------DPG 165
Query: 176 ALLDQVDISFGWSLALGWISFIAELLTG 203
+ S+GWS G SFI + G
Sbjct: 166 QRDSKKSYSYGWSFYFGAFSFIIAEIVG 193
>gi|93588657 claudin domain containing 1 protein isoform d [Homo
sapiens]
Length = 158
Score = 51.2 bits (121), Expect = 7e-07
Identities = 36/104 (34%), Positives = 52/104 (50%), Gaps = 10/104 (9%)
Query: 109 LLP-LSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFRE 167
LLP +SL LM FG + G + + ++ + TGIL L + TL +S Y+A
Sbjct: 47 LLPFVSLGLMCFGALIGLCACICRSLYPTIATGILHLLAGLCTLGSVSCYVA-------- 98
Query: 168 ALCLLEEK-ALLDQVDISFGWSLALGWISFIAELLTGAAFLAAA 210
+ LL +K L D V FGWS L +S + + A F+ AA
Sbjct: 99 GIELLHQKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAA 142
>gi|22027551 voltage-dependent calcium channel gamma-5 subunit
isoform a [Homo sapiens]
Length = 275
Score = 48.9 bits (115), Expect = 3e-06
Identities = 42/181 (23%), Positives = 76/181 (41%), Gaps = 21/181 (11%)
Query: 22 LLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTC----RVQSP 77
LL A+ TD+W ++ + ++ N+S +S HSGLWR C +
Sbjct: 23 LLGIAVSTDYWLYLE-----------EGVIVPQNQSTEIKMSLHSGLWRVCFLAGEERGR 71
Query: 78 CTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLL-QAYLLL 136
C + + SES+ +L M + +SL M G + + + +L
Sbjct: 72 CFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILA 131
Query: 137 LLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWISF 196
++GI F+ + + G+ +YI ++ + + L K + +GWS A ISF
Sbjct: 132 FVSGIFFILSGLSLVVGLVLYI----SSINDEM-LNRTKDAETYFNYKYGWSFAFAAISF 186
Query: 197 I 197
+
Sbjct: 187 L 187
>gi|7656950 voltage-dependent calcium channel gamma-5 subunit
isoform b [Homo sapiens]
Length = 296
Score = 48.9 bits (115), Expect = 3e-06
Identities = 42/181 (23%), Positives = 76/181 (41%), Gaps = 21/181 (11%)
Query: 22 LLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTC----RVQSP 77
LL A+ TD+W ++ + ++ N+S +S HSGLWR C +
Sbjct: 23 LLGIAVSTDYWLYLE-----------EGVIVPQNQSTEIKMSLHSGLWRVCFLAGEERGR 71
Query: 78 CTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLL-QAYLLL 136
C + + SES+ +L M + +SL M G + + + +L
Sbjct: 72 CFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILA 131
Query: 137 LLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWISF 196
++GI F+ + + G+ +YI ++ + + L K + +GWS A ISF
Sbjct: 132 FVSGIFFILSGLSLVVGLVLYI----SSINDEM-LNRTKDAETYFNYKYGWSFAFAAISF 186
Query: 197 I 197
+
Sbjct: 187 L 187
>gi|21361975 voltage-dependent calcium channel gamma-7 subunit [Homo
sapiens]
Length = 275
Score = 40.8 bits (94), Expect = 0.001
Identities = 39/191 (20%), Positives = 77/191 (40%), Gaps = 21/191 (10%)
Query: 12 AALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRT 71
+++ GA +L+ A+ TD+W ++ + + N++ ++ H+GLWR
Sbjct: 13 SSVFGACGLLLVGIAVSTDYWLYME-----------EGTVLPQNQTTEVKMALHAGLWRV 61
Query: 72 C----RVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 127
C R + C E V+E++ +L T +SL L+ + +
Sbjct: 62 CFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIG 121
Query: 128 FLL-QAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFG 186
+ Q +L ++GI F+ + + G+ +YI+ E+ +G
Sbjct: 122 HIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQ-----YFHYRYG 176
Query: 187 WSLALGWISFI 197
WS A SF+
Sbjct: 177 WSFAFAASSFL 187
>gi|22748835 transmembrane protein 178 [Homo sapiens]
Length = 297
Score = 38.5 bits (88), Expect = 0.005
Identities = 42/191 (21%), Positives = 73/191 (38%), Gaps = 36/191 (18%)
Query: 39 RLERTGPGAQDL--------LGSINRSQPEPL-SSHSGLWRTCR---------------V 74
RL GPG D LG ++ P+ +++SGLWR C +
Sbjct: 76 RLLPGGPGRADPESWRSLLGLGGLDAECGRPVFATYSGLWRKCYFLGIDRDIDTLILKGI 135
Query: 75 QSPCTPLM----NPFRLENV------TVSESSRQLLTMHGTFVILLPLSLILMVFGGMTG 124
CT + P RL N+ T+ + LL + L +++ +++ G +
Sbjct: 136 AQRCTAIKYHFSQPIRLRNIPFNLTKTIQQDEWHLLHLRRITAGFLGMAVAVLLCGCIVA 195
Query: 125 FLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDIS 184
+SF + L + G+LFL + + Y A + L+ +L V+
Sbjct: 196 TVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASISYDLNRLPKLI--YSLPADVEHG 253
Query: 185 FGWSLALGWIS 195
+ WS+ W S
Sbjct: 254 YSWSIFCAWCS 264
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 36.2 bits (82), Expect = 0.023
Identities = 38/168 (22%), Positives = 72/168 (42%), Gaps = 11/168 (6%)
Query: 64 SHSGLWRTC-RVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGM 122
++ GLWR+C R S T F L + + + L + G ++L + L++ +F
Sbjct: 45 NYQGLWRSCVRESSGFTECRGYFTLLGLPAMLQAVRALMIVG--IVLGAIGLLVSIFALK 102
Query: 123 T---GFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEE----K 175
G + +A + L +GI+F+ + +AG+SV+ F + +
Sbjct: 103 CIRIGSMEDSAKANMTLT-SGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGM 161
Query: 176 ALLDQVDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI 223
Q +FG +L +GW++ L+ G A R L+ +A+
Sbjct: 162 VQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLAPEETNYKAV 209
>gi|5031949 natural killer cell group 7 sequence [Homo sapiens]
Length = 165
Score = 35.4 bits (80), Expect = 0.039
Identities = 49/199 (24%), Positives = 72/199 (36%), Gaps = 54/199 (27%)
Query: 12 AALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRT 71
A L G+L + A+ TDFW+ E GP S+HSGLW T
Sbjct: 8 ALLGGSLGLMFCLIALSTDFWF-------EAVGPTH---------------SAHSGLWPT 45
Query: 72 CRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPL-SLILMVFGGMTGFLSFLL 130
+ + + TF I+ L +L+ + F ++ F S
Sbjct: 46 GH-------------------GDIISGYIHVTQTFSIMAVLWALVSVSFLVLSCFPSLFP 86
Query: 131 QAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLA 190
+ L+ T F A IS+ +A + ++ Q+ F WS
Sbjct: 87 PGHGPLVSTTAAFA-------AAISMVVAMAVYTSERW-----DQPPHPQIQTFFSWSFY 134
Query: 191 LGWISFIAELLTGAAFLAA 209
LGW+S I L TGA L A
Sbjct: 135 LGWVSAILLLCTGALSLGA 153
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 35.0 bits (79), Expect = 0.051
Identities = 50/223 (22%), Positives = 86/223 (38%), Gaps = 34/223 (15%)
Query: 12 AALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRT 71
A L L AA G D W QDL + S + + GLWR+
Sbjct: 10 AFLLSILGLAGCIAATGMDMW-------------STQDLYDNPVTS----VFQYEGLWRS 52
Query: 72 CRVQSP----CTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMT---G 124
C QS C P L + ++ R L+ + ++L + L++ +F G
Sbjct: 53 CVRQSSGFTECRPYFTILGLP--AMLQAVRALMIVG---IVLGAIGLLVSIFALKCIRIG 107
Query: 125 FLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEE----KALLDQ 180
+ +A + L +GI+F+ + +AG+SV+ F + + Q
Sbjct: 108 SMEDSAKANMTLT-SGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQ 166
Query: 181 VDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI 223
+FG +L +GW++ L+ G A R L+ +A+
Sbjct: 167 TRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLAPEETNYKAV 209
>gi|71999143 opsin 4 isoform 2 [Homo sapiens]
Length = 489
Score = 34.3 bits (77), Expect = 0.088
Identities = 43/135 (31%), Positives = 56/135 (41%), Gaps = 15/135 (11%)
Query: 87 LENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLLQAYLLLLLTGILF--- 143
L VTV SR L T F+I L +S LM F F + L L TG F
Sbjct: 100 LRGVTVMMQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAF 159
Query: 144 ---LFG--AMVTLAGIS----VYIAYSAAAFREALCLLEEKALLDQVDISFGWSLA--LG 192
LFG +M+TL I+ + I A F A LL + WSL G
Sbjct: 160 CGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFG 219
Query: 193 WISFIAE-LLTGAAF 206
W +++ E LLT ++
Sbjct: 220 WSAYVPEGLLTSCSW 234
>gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2
[Homo sapiens]
Length = 173
Score = 33.9 bits (76), Expect = 0.11
Identities = 33/158 (20%), Positives = 58/158 (36%), Gaps = 31/158 (19%)
Query: 64 SHSGLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMT 123
+H GLWR C + + C + N T + F+IL S + + G +
Sbjct: 38 AHQGLWRYC-LGNKCYLQTDSIAYWNATRA------------FMIL---SALCAISGIIM 81
Query: 124 GFLSFLLQAYLLLLL----TGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLD 179
G ++F Q + GI+F + + +++Y + +
Sbjct: 82 GIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYTGVTVSFLGRRFG--------- 132
Query: 180 QVDISFGWSLALGWISFIAELLTGAAFLAAARELSLRR 217
D F WS LGW++ + G ++ A R RR
Sbjct: 133 --DWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRR 168
>gi|4503561 epithelial membrane protein 2 [Homo sapiens]
Length = 167
Score = 33.9 bits (76), Expect = 0.11
Identities = 33/145 (22%), Positives = 59/145 (40%), Gaps = 26/145 (17%)
Query: 68 LWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLS 127
+WR C + CT +++S ++ T+ ++ LS IL F
Sbjct: 38 VWRICTNNTNCT-----------VINDSFQEYSTLQAVQATMI-LSTILCCIA----FFI 81
Query: 128 FLLQAYLL-----LLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVD 182
F+LQ + L +LT I+ L + + S+Y RE + K +
Sbjct: 82 FVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYTDR-----REDIHDKNAKFYPVTRE 136
Query: 183 ISFGWSLALGWISFIAELLTGAAFL 207
S+G+S L W++F ++G +L
Sbjct: 137 GSYGYSYILAWVAFACTFISGMMYL 161
>gi|169171558 PREDICTED: hypothetical protein [Homo sapiens]
Length = 303
Score = 32.3 bits (72), Expect = 0.33
Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Query: 112 LSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCL 171
+++ +++FG + G L L+ + G+LFL G T IS+ + F +
Sbjct: 186 MAVAIILFGWIIGVLGCCWDRGLMQYVAGLLFLMGG--TFCIISLCTCVAGINFELSRYP 243
Query: 172 LEEKALLDQVDISFGWSLALGWISFIAELLTG 203
L D + +GWS+ W L++G
Sbjct: 244 RYLYGLPDDISHGYGWSMFCAWGGLGLTLISG 275
>gi|169171977 PREDICTED: hypothetical protein [Homo sapiens]
Length = 195
Score = 32.3 bits (72), Expect = 0.33
Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Query: 112 LSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCL 171
+++ +++FG + G L L+ + G+LFL G T IS+ + F +
Sbjct: 78 MAVAIILFGWIIGVLGCCWDRGLMQYVAGLLFLMGG--TFCIISLCTCVAGINFELSRYP 135
Query: 172 LEEKALLDQVDISFGWSLALGWISFIAELLTG 203
L D + +GWS+ W L++G
Sbjct: 136 RYLYGLPDDISHGYGWSMFCAWGGLGLTLISG 167
>gi|169171016 PREDICTED: hypothetical protein [Homo sapiens]
Length = 195
Score = 32.3 bits (72), Expect = 0.33
Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Query: 112 LSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCL 171
+++ +++FG + G L L+ + G+LFL G T IS+ + F +
Sbjct: 78 MAVAIILFGWIIGVLGCCWDRGLMQYVAGLLFLMGG--TFCIISLCTCVAGINFELSRYP 135
Query: 172 LEEKALLDQVDISFGWSLALGWISFIAELLTG 203
L D + +GWS+ W L++G
Sbjct: 136 RYLYGLPDDISHGYGWSMFCAWGGLGLTLISG 167
>gi|239509059 PREDICTED: hypothetical protein [Homo sapiens]
Length = 195
Score = 32.3 bits (72), Expect = 0.33
Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Query: 112 LSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCL 171
+++ +++FG + G L L+ + G+LFL G T IS+ + F +
Sbjct: 78 MAVAIILFGWIIGVLGCCWDRGLMQYVAGLLFLMGG--TFCIISLCTCVAGINFELSRYP 135
Query: 172 LEEKALLDQVDISFGWSLALGWISFIAELLTG 203
L D + +GWS+ W L++G
Sbjct: 136 RYLYGLPDDISHGYGWSMFCAWGGLGLTLISG 167
>gi|4503563 epithelial membrane protein 3 [Homo sapiens]
Length = 163
Score = 31.6 bits (70), Expect = 0.57
Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 20/105 (19%)
Query: 108 ILLPLSLILMVFGGMTGFLSFLLQAYL-----LLLLTGILFLFGAMVTLAGISVYIAYSA 162
+L+ LSLIL F+ F+ Q Y L TG+ L ++ G +Y ++
Sbjct: 68 VLMVLSLILCCLS----FILFMFQLYTMRRGGLFYATGLCQLCTSVAVFTGALIYAIHA- 122
Query: 163 AAFREALCLLEEKALLDQVDISFGWSLALGWISFIAELLTGAAFL 207
EE SFG+ AL W++F L++G ++
Sbjct: 123 ----------EEILEKHPRGGSFGYCFALAWVAFPLALVSGIIYI 157
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 31.2 bits (69), Expect = 0.74
Identities = 38/154 (24%), Positives = 55/154 (35%), Gaps = 25/154 (16%)
Query: 67 GLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFL 126
GLW+TC +Q F +E L +S ILM GFL
Sbjct: 49 GLWQTCVIQEEVGMQCKDFDSFLALPAE---------------LRVSRILMFLSNGLGFL 93
Query: 127 SFLLQAYLLLLLT----------GILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKA 176
L+ + L L +L L G + +GI+ + S A + +E
Sbjct: 94 GLLVSGFGLDCLRIGESQRDLKRRLLILGGILSWASGITALVPVSWVAHKTVQEFWDENV 153
Query: 177 LLDQVDISFGWSLALGWISFIAELLTGAAFLAAA 210
FG +L LGW + ++ LL G AA
Sbjct: 154 PDFVPRWEFGEALFLGWFAGLSLLLGGCLLNCAA 187
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.140 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,307,919
Number of Sequences: 37866
Number of extensions: 293662
Number of successful extensions: 1140
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 1076
Number of HSP's gapped (non-prelim): 62
length of query: 223
length of database: 18,247,518
effective HSP length: 98
effective length of query: 125
effective length of database: 14,536,650
effective search space: 1817081250
effective search space used: 1817081250
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.