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Search of human proteins with 239756009
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239756009 PREDICTED: similar to transmembrane
phosphoinositide 3-phosphatase and tensin homolog 2, partial [Homo
sapiens]
(99 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239756009 PREDICTED: similar to transmembrane phosphoinositid... 206 4e-54
gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase... 109 5e-25
gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase... 109 5e-25
gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase... 109 5e-25
gi|40549435 transmembrane phosphatase with tensin homology isofo... 103 2e-23
gi|40549433 transmembrane phosphatase with tensin homology isofo... 103 2e-23
gi|109689707 transmembrane phosphatase with tensin homology isof... 103 2e-23
gi|73765544 phosphatase and tensin homolog [Homo sapiens] 53 6e-08
gi|157384971 cyclin G associated kinase [Homo sapiens] 45 9e-06
gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo sap... 42 8e-05
gi|169173235 PREDICTED: hypothetical protein [Homo sapiens] 41 2e-04
gi|65288071 tensin 3 [Homo sapiens] 39 0.001
gi|66529407 tensin [Homo sapiens] 35 0.010
gi|38787970 tensin like C1 domain containing phosphatase isoform... 35 0.017
gi|38787957 tensin like C1 domain containing phosphatase isoform... 35 0.017
gi|38787941 tensin like C1 domain containing phosphatase isoform... 35 0.017
gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I... 27 2.7
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 27 3.5
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 27 3.5
gi|33383239 protein kinase Myt1 isoform 2 [Homo sapiens] 27 3.5
gi|6005900 transcription factor Dp-1 [Homo sapiens] 27 4.6
gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens] 27 4.6
gi|110349719 titin isoform N2-A [Homo sapiens] 26 6.0
gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens] 26 6.0
gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens] 26 6.0
gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens] 26 6.0
gi|118343647 heat shock protein family B (small), member 11 [Hom... 26 6.0
gi|224586784 hypothetical protein LOC731220 [Homo sapiens] 26 7.8
>gi|239756009 PREDICTED: similar to transmembrane phosphoinositide
3-phosphatase and tensin homolog 2, partial [Homo
sapiens]
Length = 99
Score = 206 bits (523), Expect = 4e-54
Identities = 99/99 (100%), Positives = 99/99 (100%)
Query: 1 SLLPCSLISDCCASNQRDSVGVGPSKPGERAYDPKHFHNRVSRIMIDDHNVPTLREMVAF 60
SLLPCSLISDCCASNQRDSVGVGPSKPGERAYDPKHFHNRVSRIMIDDHNVPTLREMVAF
Sbjct: 1 SLLPCSLISDCCASNQRDSVGVGPSKPGERAYDPKHFHNRVSRIMIDDHNVPTLREMVAF 60
Query: 61 SKEVLEWMAQDSENIVVIHCKGGKVIFKVVLKLGENLLD 99
SKEVLEWMAQDSENIVVIHCKGGKVIFKVVLKLGENLLD
Sbjct: 61 SKEVLEWMAQDSENIVVIHCKGGKVIFKVVLKLGENLLD 99
>gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase
isoform delta [Homo sapiens]
Length = 411
Score = 109 bits (272), Expect = 5e-25
Identities = 50/56 (89%), Positives = 51/56 (91%)
Query: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGGK 84
ERAYDPKHFHNRVSRIMIDDHNVPTL EMV F+KEV EWMAQD ENIV IHCKGGK
Sbjct: 158 ERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGK 213
>gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase
isoform gamma [Homo sapiens]
Length = 522
Score = 109 bits (272), Expect = 5e-25
Identities = 50/56 (89%), Positives = 51/56 (91%)
Query: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGGK 84
ERAYDPKHFHNRVSRIMIDDHNVPTL EMV F+KEV EWMAQD ENIV IHCKGGK
Sbjct: 269 ERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGK 324
>gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase
isoform alpha [Homo sapiens]
Length = 445
Score = 109 bits (272), Expect = 5e-25
Identities = 50/56 (89%), Positives = 51/56 (91%)
Query: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGGK 84
ERAYDPKHFHNRVSRIMIDDHNVPTL EMV F+KEV EWMAQD ENIV IHCKGGK
Sbjct: 192 ERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGK 247
>gi|40549435 transmembrane phosphatase with tensin homology isoform
gamma [Homo sapiens]
Length = 513
Score = 103 bits (258), Expect = 2e-23
Identities = 47/55 (85%), Positives = 49/55 (89%)
Query: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGG 83
ERAYDPKHFHNRV RIMIDDHNVPTL +MV F+KEV EWMAQD ENIV IHCKGG
Sbjct: 249 ERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGG 303
>gi|40549433 transmembrane phosphatase with tensin homology isoform
beta [Homo sapiens]
Length = 533
Score = 103 bits (258), Expect = 2e-23
Identities = 47/55 (85%), Positives = 49/55 (89%)
Query: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGG 83
ERAYDPKHFHNRV RIMIDDHNVPTL +MV F+KEV EWMAQD ENIV IHCKGG
Sbjct: 269 ERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGG 323
>gi|109689707 transmembrane phosphatase with tensin homology isoform
alpha [Homo sapiens]
Length = 551
Score = 103 bits (258), Expect = 2e-23
Identities = 47/55 (85%), Positives = 49/55 (89%)
Query: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGG 83
ERAYDPKHFHNRV RIMIDDHNVPTL +MV F+KEV EWMAQD ENIV IHCKGG
Sbjct: 287 ERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGG 341
>gi|73765544 phosphatase and tensin homolog [Homo sapiens]
Length = 403
Score = 52.8 bits (125), Expect = 6e-08
Identities = 21/56 (37%), Positives = 35/56 (62%)
Query: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGGK 84
ER YD F+ RV++ +DHN P L + F +++ +W+++D ++ IHCK GK
Sbjct: 73 ERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGK 128
>gi|157384971 cyclin G associated kinase [Homo sapiens]
Length = 1311
Score = 45.4 bits (106), Expect = 9e-06
Identities = 20/62 (32%), Positives = 29/62 (46%)
Query: 30 RAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGGKVIFKV 89
R Y P FHNRVS P L + + + W+ QD +N+ V+HC G+ V
Sbjct: 458 RTYRPSRFHNRVSECGWAARRAPHLHTLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAV 517
Query: 90 VL 91
+
Sbjct: 518 AV 519
>gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo
sapiens]
Length = 913
Score = 42.4 bits (98), Expect = 8e-05
Identities = 16/62 (25%), Positives = 32/62 (51%)
Query: 30 RAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGGKVIFKV 89
++Y FH+RVS P+L + A + + W+ Q+ +N+ V+HC G+ +
Sbjct: 114 KSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSI 173
Query: 90 VL 91
++
Sbjct: 174 LV 175
>gi|169173235 PREDICTED: hypothetical protein [Homo sapiens]
Length = 331
Score = 41.2 bits (95), Expect = 2e-04
Identities = 19/27 (70%), Positives = 22/27 (81%)
Query: 1 SLLPCSLISDCCASNQRDSVGVGPSKP 27
SL P SLIS+CCASN+ SVG+ PSKP
Sbjct: 185 SLPPGSLISNCCASNEGGSVGIQPSKP 211
>gi|65288071 tensin 3 [Homo sapiens]
Length = 1445
Score = 38.5 bits (88), Expect = 0.001
Identities = 18/63 (28%), Positives = 33/63 (52%)
Query: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGGKVIFK 88
E+ YD + ++ + + + P L +M K W+ + +++VVIHC+GGK
Sbjct: 56 EKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIG 115
Query: 89 VVL 91
VV+
Sbjct: 116 VVI 118
>gi|66529407 tensin [Homo sapiens]
Length = 1735
Score = 35.4 bits (80), Expect = 0.010
Identities = 19/63 (30%), Positives = 30/63 (47%)
Query: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGGKVIFK 88
ER D H +V D + P L ++ + K + W+ D N+VV+H KG +
Sbjct: 62 ERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIG 121
Query: 89 VVL 91
VV+
Sbjct: 122 VVI 124
>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
[Homo sapiens]
Length = 1285
Score = 34.7 bits (78), Expect = 0.017
Identities = 14/56 (25%), Positives = 31/56 (55%)
Query: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGGK 84
E+ +D + +V + + P L ++ + K + W++ D +++VV++CKG K
Sbjct: 56 EKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNK 111
>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
[Homo sapiens]
Length = 1409
Score = 34.7 bits (78), Expect = 0.017
Identities = 14/56 (25%), Positives = 31/56 (55%)
Query: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGGK 84
E+ +D + +V + + P L ++ + K + W++ D +++VV++CKG K
Sbjct: 180 EKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNK 235
>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
[Homo sapiens]
Length = 1419
Score = 34.7 bits (78), Expect = 0.017
Identities = 14/56 (25%), Positives = 31/56 (55%)
Query: 29 ERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSENIVVIHCKGGK 84
E+ +D + +V + + P L ++ + K + W++ D +++VV++CKG K
Sbjct: 190 EKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNK 245
>gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I
subunit isoform a [Homo sapiens]
Length = 2223
Score = 27.3 bits (59), Expect = 2.7
Identities = 8/17 (47%), Positives = 13/17 (76%)
Query: 24 PSKPGERAYDPKHFHNR 40
P+KPG A +P+H+H +
Sbjct: 474 PAKPGPHAKEPRHYHGK 490
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 26.9 bits (58), Expect = 3.5
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Query: 1 SLLPCSLISDCCASNQRDS-VGVGPSKPGERAYDPKHFHNRVSRIMIDDHNVPTLREMV 58
+++P + +Q DS + V + G + + KH + + I DHN+PTL +V
Sbjct: 831 TIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTLEAVV 889
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 26.9 bits (58), Expect = 3.5
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Query: 1 SLLPCSLISDCCASNQRDS-VGVGPSKPGERAYDPKHFHNRVSRIMIDDHNVPTLREMV 58
+++P + +Q DS + V + G + + KH + + I DHN+PTL +V
Sbjct: 915 TIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTLEAVV 973
>gi|33383239 protein kinase Myt1 isoform 2 [Homo sapiens]
Length = 480
Score = 26.9 bits (58), Expect = 3.5
Identities = 13/36 (36%), Positives = 17/36 (47%)
Query: 4 PCSLISDCCASNQRDSVGVGPSKPGERAYDPKHFHN 39
PCSL+ D S+ D +GP P A P H+
Sbjct: 418 PCSLLLDSSLSSNWDDDSLGPGHPPCLACPPAGLHS 453
>gi|6005900 transcription factor Dp-1 [Homo sapiens]
Length = 410
Score = 26.6 bits (57), Expect = 4.6
Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 10/57 (17%)
Query: 27 PGERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWM------AQDSENIVV 77
P E AYD K+ RV D NV +++ K+ ++W+ AQ+ +N+ V
Sbjct: 155 PNESAYDQKNIRRRV----YDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEV 207
>gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens]
Length = 1007
Score = 26.6 bits (57), Expect = 4.6
Identities = 10/25 (40%), Positives = 15/25 (60%)
Query: 24 PSKPGERAYDPKHFHNRVSRIMIDD 48
PSK ++ D +H H RV+ + DD
Sbjct: 864 PSKEDDKEIDLEHLHRRVNSLCTDD 888
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 26.2 bits (56), Expect = 6.0
Identities = 10/41 (24%), Positives = 19/41 (46%)
Query: 33 DPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVLEWMAQDSE 73
+P F R+ I++ +H T V+F ++ W +E
Sbjct: 8832 EPIQFTKRIQNIVVSEHQSATFECEVSFDDAIVTWYKGPTE 8872
>gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens]
Length = 643
Score = 26.2 bits (56), Expect = 6.0
Identities = 12/49 (24%), Positives = 23/49 (46%)
Query: 17 RDSVGVGPSKPGERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVL 65
R SV +K Y+ + + + +D HN+ +RE + KE++
Sbjct: 322 RPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIV 370
>gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 26.2 bits (56), Expect = 6.0
Identities = 12/49 (24%), Positives = 23/49 (46%)
Query: 17 RDSVGVGPSKPGERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVL 65
R SV +K Y+ + + + +D HN+ +RE + KE++
Sbjct: 250 RPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIV 298
>gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 26.2 bits (56), Expect = 6.0
Identities = 12/49 (24%), Positives = 23/49 (46%)
Query: 17 RDSVGVGPSKPGERAYDPKHFHNRVSRIMIDDHNVPTLREMVAFSKEVL 65
R SV +K Y+ + + + +D HN+ +RE + KE++
Sbjct: 250 RPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIV 298
>gi|118343647 heat shock protein family B (small), member 11 [Homo
sapiens]
Length = 144
Score = 26.2 bits (56), Expect = 6.0
Identities = 15/50 (30%), Positives = 28/50 (56%), Gaps = 8/50 (16%)
Query: 36 HFHNRVSRIMIDDHNVPTLREMVAFSKEVL---EWMAQDSENIVVIHCKG 82
H H R+ R++I + V TL+ + SKE + +W+ +D ++H +G
Sbjct: 54 HKHVRIERLVIQSYFVQTLKIEKSTSKEPVDFEQWIEKD-----LVHTEG 98
>gi|224586784 hypothetical protein LOC731220 [Homo sapiens]
Length = 473
Score = 25.8 bits (55), Expect = 7.8
Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 6 SLISDCCASNQRDSVGVGPSKPGERAYDPKHFHNRVSRIM 45
S +S CAS + +GV P+ G+ Y P N V RI+
Sbjct: 366 SSLSQACASPSMEPLGVMPTHMGQGRY-PVGVSNMVLRIL 404
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,870,971
Number of Sequences: 37866
Number of extensions: 133452
Number of successful extensions: 381
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 356
Number of HSP's gapped (non-prelim): 28
length of query: 99
length of database: 18,247,518
effective HSP length: 70
effective length of query: 29
effective length of database: 15,596,898
effective search space: 452310042
effective search space used: 452310042
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.