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Search of human proteins with 239754909
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
(245 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 484 e-137
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 268 4e-72
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 163 1e-40
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 147 8e-36
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 146 1e-35
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 145 3e-35
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 144 9e-35
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 135 4e-32
gi|148746195 trichohyalin [Homo sapiens] 128 4e-30
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 127 9e-30
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 125 4e-29
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 125 4e-29
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 120 8e-28
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 117 7e-27
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 117 1e-26
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 115 3e-26
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 115 3e-26
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 114 8e-26
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 112 2e-25
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 112 3e-25
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 112 4e-25
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 110 9e-25
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 110 9e-25
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 110 1e-24
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 109 2e-24
gi|52426743 cisplatin resistance-associated overexpressed protei... 109 2e-24
gi|19923485 cisplatin resistance-associated overexpressed protei... 109 2e-24
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 106 2e-23
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 104 8e-23
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 104 8e-23
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 484 bits (1245), Expect = e-137
Identities = 245/245 (100%), Positives = 245/245 (100%)
Query: 1 MVKAISSRAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERK 60
MVKAISSRAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERK
Sbjct: 1 MVKAISSRAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERK 60
Query: 61 KERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEK 120
KERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEK
Sbjct: 61 KERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEK 120
Query: 121 KERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180
KERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE
Sbjct: 121 KERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180
Query: 181 KERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRER 240
KERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRER
Sbjct: 181 KERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRER 240
Query: 241 KERKK 245
KERKK
Sbjct: 241 KERKK 245
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 268 bits (684), Expect = 4e-72
Identities = 148/236 (62%), Positives = 184/236 (77%), Gaps = 31/236 (13%)
Query: 1 MVKAISSRAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERK 60
MVKAISSRAAVKLNTELQMVSCSHISKPCTQ RESERK
Sbjct: 1 MVKAISSRAAVKLNTELQMVSCSHISKPCTQ-----------------------RESERK 37
Query: 61 KERREREKRKREREKERKRERGKKEKKGERKKE---ERERKKRRREKENKEGEEKE--KR 115
KERREREKRKREREKERKRERGKKEKK +K+E ERERK++ REK+ KE EKE KR
Sbjct: 38 KERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKR 97
Query: 116 KKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRER-KQVGEK 174
K KEKK+R R + +ER++K+ERK ER+ ++R++ +R+K R++K RK+R+R K+ G++
Sbjct: 98 K-KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKR 156
Query: 175 EEERKEKERKER-KKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTN 229
E +RK+++++ER KKRERNRKERKKERERKERRERKKERKK+ +KKER+KDR+T+
Sbjct: 157 ERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTD 212
Score = 65.1 bits (157), Expect = 5e-11
Identities = 36/110 (32%), Positives = 67/110 (60%), Gaps = 13/110 (11%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKRERE----------KERKRERGKKEK-- 86
RER+R+ +K+ +KER+ E+++ +RER+++KR++E KERK+ER +KE+
Sbjct: 131 RERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRE 190
Query: 87 -KGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER 135
K ERKKE R++K+R+++++ + + + + R + G R R
Sbjct: 191 RKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYR 240
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 163 bits (412), Expect = 1e-40
Identities = 82/215 (38%), Positives = 154/215 (71%), Gaps = 12/215 (5%)
Query: 39 REREREIETRKEGKKERESERKKER-RERE-----KRKREREKERKRERGKKEKKGERKK 92
R+R+RE E ++ ++ERE+ER+ ER R+R+ +R+R+R+ E++RER + +++ +R+
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER-QTDRERQRQT 171
Query: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE-ERKERERKK 151
E +K+R REK +E E+E++++KE K R S+ G+ERER+ E + E ERK + ++
Sbjct: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
Query: 152 EEREKERERKERKKRERKQVGEKEEER-KEKERKERKKRERNRKERKKERERKERRERKK 210
+R+++ ER+ K+ ER++ E+E ER KE+ER+ + R+R+R+++++ER+ +R+R+
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291
Query: 211 ERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
ER ++ ERK+ERQ++R+ RE+ER ++ +ER++
Sbjct: 292 ERDRETERKRERQRERE---RERERNRKRERERER 323
Score = 160 bits (406), Expect = 7e-40
Identities = 86/235 (36%), Positives = 152/235 (64%), Gaps = 30/235 (12%)
Query: 39 REREREIETRKEGKK--------ERESERKKERREREKRKREREKERKRERGK-KEKKGE 89
R++ERE ET +EG++ +RE ER+++ + +R+ +RE++R+ ER + KE++ E
Sbjct: 123 RQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERERE 182
Query: 90 RKKEERERKKRRREKENK-------EGEEKEK---------RKKKEKKERGRTSKEGKER 133
+ ++ER ++R+REKENK G E+E+ RK++ +ER R K +ER
Sbjct: 183 KNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERER 242
Query: 134 ERKEERKREERKERERKKE---EREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190
E++ ER+R +E ER KE ER+++R+R R+K +Q K + R E++R+ +KRE
Sbjct: 243 EKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302
Query: 191 RNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
R R ER++ERER +RER++ER+++ ER++E ++DR+ RE++R ++ +R++
Sbjct: 303 RQR-ERERERERNRKRERERERERERERQRETERDREKE-RERKRKRQTEMDRER 355
Score = 156 bits (394), Expect = 2e-38
Identities = 87/233 (37%), Positives = 148/233 (63%), Gaps = 30/233 (12%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERER- 97
RERERE ET E +++R+++R+++R+ K +REREK+ +RER + + K+ ERER
Sbjct: 210 RERERERETETETERKRQTDRERDRQR--KTEREREKQAERERASERETERDKERERERD 267
Query: 98 KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE----- 152
+ R R++ KE E + RK++ + ER R ++ +ER+R+ ER+RE ++RER++E
Sbjct: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERER 327
Query: 153 --------EREKERERKERKK------------RERKQVGEKEEERKEKERKERKKRERN 192
+REKERERK +++ RE ++ E+E ER E+ER + RER
Sbjct: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERER-ERERDRQSARERE 386
Query: 193 RKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+ER ++R+R++ RER+ E+ + +R+ E+Q++R+ + RE ERG+ +ER+K
Sbjct: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKD-RESERGRERGREREK 438
Score = 152 bits (383), Expect = 3e-37
Identities = 89/219 (40%), Positives = 149/219 (68%), Gaps = 18/219 (8%)
Query: 39 REREREIETRKEGKK-ERESERKKERREREK---RKREREKERKRERGK-KEKKGERKKE 93
R R++E E R+E ++ ERE++RK+ERR REK RKR+R +ER+R+R K +E++ +R+++
Sbjct: 56 RNRQKERERRREKRQTERETDRKRERR-REKDRHRKRDRHRERQRDREKERERQTDRERD 114
Query: 94 ERERKKRRREKE-----NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE 148
+ K+R R+KE +EGE R+ ++ER R KERER+ +R+R+ + ER
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
Query: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR-KERKKERERKERRE 207
R+K ERE+E+ R+ER++RER ++E+E K ++R + RER R +E + E ERK + +
Sbjct: 175 RQK-EREREKNRQERRERER----QREKENKTEDRHSERGRERERERETETETERKRQTD 229
Query: 208 RKKERKKKEERKKERQKDRQ-TNWREKERGKRERKERKK 245
R+++R++K ER++E+Q +R+ + RE ER K +ER +
Sbjct: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDR 268
Score = 152 bits (383), Expect = 3e-37
Identities = 87/224 (38%), Positives = 143/224 (63%), Gaps = 17/224 (7%)
Query: 39 REREREIETRKEGKKERESERKKERREREK-----RKREREKERKRERGKKEKKGERKKE 93
RERE+ + R+E +++RE E K E R E+ R+RE E E +R+R ++ ++K
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238
Query: 94 ERERKKR-RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
ERER+K+ RE+ ++ E++K +++E+ + KERER+ +RKR+ R ER+R+ E
Sbjct: 239 EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298
Query: 153 -----EREKERERKERKKRERKQVGEKEEER-KEKERKERKKRERNRK---ERKKERERK 203
+RE+ERER+ +KRER++ E+E ER +E ER K+RER RK E +ER R+
Sbjct: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
Query: 204 ERRE--RKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
RE R+ ER+++ ER+++RQ R+ RE++R + +KER++
Sbjct: 359 TGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERER 402
Score = 148 bits (374), Expect = 4e-36
Identities = 89/248 (35%), Positives = 143/248 (57%), Gaps = 53/248 (21%)
Query: 39 REREREIETRKEGKKERESERKKER---REREK---------RKREREKERKRERGKKEK 86
RERERE ET E K++ + ER ++R REREK R+ ER+KER+RER +
Sbjct: 212 RERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRD 271
Query: 87 KGERKKE---ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143
+ R+KE + +RK++RR + ++E E K +R+++ ++ER R K +ERER+ ER+R+
Sbjct: 272 RDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR 331
Query: 144 RKERERKKEE-----------------------REKERERKERKKRERKQVGEKEEERKE 180
ER+R+KE R+ ERER+ ++R+R+ E+EE ++
Sbjct: 332 ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD 391
Query: 181 KERKERKKRERN-------------RKERKKERERKERRERKKERKKKE--ERKKERQKD 225
++R +K+RER ++ER+K+RE + RER +ER+K++ ER +ERQ D
Sbjct: 392 RDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTD 451
Query: 226 RQTNWREK 233
RQ + K
Sbjct: 452 RQAGRQRK 459
Score = 148 bits (374), Expect = 4e-36
Identities = 72/201 (35%), Positives = 144/201 (71%), Gaps = 11/201 (5%)
Query: 39 REREREIET---RKEGKKERESERKKERR-EREK---RKREREKERKRERGKKEKKGERK 91
RERER+ + R++ ++ER+++RK++RR ER++ RKRER++ER+RER + K+ +
Sbjct: 262 RERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERER 321
Query: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE--- 148
+ ERER+++R + ++E E + KRK++ + +R R + G+E R+ ER+RE +ER+
Sbjct: 322 ERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQS 381
Query: 149 -RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207
R++EERE++R+R +K+RER+ +++ +R+ ++++ER+K + + R++ RER++++
Sbjct: 382 AREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKG 441
Query: 208 RKKERKKKEERKKERQKDRQT 228
R+++R+++ +R+ RQ+ R T
Sbjct: 442 RERDRERQTDRQAGRQRKRST 462
Score = 147 bits (370), Expect = 1e-35
Identities = 75/215 (34%), Positives = 144/215 (66%), Gaps = 11/215 (5%)
Query: 39 REREREIETRKEGK-KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERER 97
RER+RE E + E + ER ER++ER + +R+R+ +R+R+R +K ++ K+ ERER
Sbjct: 191 RERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERER 250
Query: 98 KKRR-------REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
R RE+E ++++R+K+ +++ R + ER+R+ ERKRE ++ERER+
Sbjct: 251 ASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERE 310
Query: 151 KEE-REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERK 209
+E R++ERER+ ++RER++ E++ E KE+ERK +++ E +R ER ++ R+ RR+ +
Sbjct: 311 RERNRKRERERERERERERQRETERDRE-KERERKRKRQTEMDR-ERNRQTGREGRRQAE 368
Query: 210 KERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
+ER+++ ER ++ ++R+ R+++R +++ +ER+
Sbjct: 369 RERERERERDRQSAREREERERDRDRDRQKERERQ 403
Score = 143 bits (360), Expect = 2e-34
Identities = 84/220 (38%), Positives = 142/220 (64%), Gaps = 10/220 (4%)
Query: 31 QPGWQSEIREREREIETRKEGKKERESERKKER-REREKRKREREKERKRERGKKEKKGE 89
+PG Q R R + +RE R+KER R REKR+ ERE +RKRER ++EK
Sbjct: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRER-RREKDRH 88
Query: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
RK++ ++R REKE + ++E+ +++E KER R + +E ER+ ER R+ + + +R
Sbjct: 89 RKRDRHRERQRDREKERERQTDRERDRQRE-KERNRQKERERETEREGERGRDRQTDGQR 147
Query: 150 KKE---EREKERERKERKKRERKQVGEKEEER-KEKERKERKKRERNRKERKKERERKER 205
++E + EKERER+ ++R+R+ +++ER +EK R+ER++RER R++ K +R
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE 207
Query: 206 RERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
R R++ER+++ E + ER+ RQT+ RE++R ++ +ER+K
Sbjct: 208 RGRERERERETETETERK--RQTD-RERDRQRKTEREREK 244
Score = 134 bits (337), Expect = 7e-32
Identities = 65/202 (32%), Positives = 126/202 (62%), Gaps = 10/202 (4%)
Query: 44 EIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE 103
+ R+ G +E R + ++ +RE+ R++ER ++ +K + ++E +++RRRE
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
Query: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER-KKEEREKERERKE 162
K+ R +K + R R KERER+ +R+R+ ++E+ER +++ERE+E ER+
Sbjct: 85 KD---------RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135
Query: 163 RKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKER 222
+ R+R+ G++E ER+ KER+++ ++R+ ER R++ RER+K R+++ ER+++R
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQR 195
Query: 223 QKDRQTNWREKERGKRERKERK 244
+K+ +T R ERG+ +ER+
Sbjct: 196 EKENKTEDRHSERGRERERERE 217
Score = 93.2 bits (230), Expect = 2e-19
Identities = 43/133 (32%), Positives = 88/133 (66%), Gaps = 1/133 (0%)
Query: 114 KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGE 173
+R ++ R R + + ++R+R +KERER++E+R+ ERE +++R R++
Sbjct: 29 RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88
Query: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTN-WRE 232
++ +R + +++R+K + +R+++R+R++ R R+KER+++ ER+ ER +DRQT+ RE
Sbjct: 89 RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE 148
Query: 233 KERGKRERKERKK 245
+ER + KER++
Sbjct: 149 RERQRDAEKERER 161
Score = 90.9 bits (224), Expect = 9e-19
Identities = 65/216 (30%), Positives = 112/216 (51%), Gaps = 32/216 (14%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKK-----EKKGERKKE 93
RERERE E +E ++E E +R+KER + KR+ E ++ER R+ G++ E++ ER++E
Sbjct: 317 RERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERE 376
Query: 94 E-----RERKKRRREKENKEGEEKEKRKKKEK-------KERGRTSKEGKERERKEERKR 141
RER++R R+++ +E+E++ +K++ K+R R ER R+ R+R
Sbjct: 377 RDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRER 436
Query: 142 EERKERERKKEEREKERERKERKKRERKQVGEKEEE------RKEKERKERKKRERNRKE 195
E++K RER + ER+ +R+ ++KR V + + R R R ++ E
Sbjct: 437 EKQKGRERDR-ERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPE 495
Query: 196 RKKE--------RERKERRERKKERKKKEERKKERQ 223
K R K R R R++ E R E++
Sbjct: 496 DPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKR 531
Score = 56.2 bits (134), Expect = 2e-08
Identities = 49/166 (29%), Positives = 80/166 (48%), Gaps = 23/166 (13%)
Query: 35 QSEIREREREIETRKEGKKERESERKKER---REREKRKREREKERKRERGKKEKKGERK 91
QS ERE + ++ +KERE + +K+R RE EK +REREK+R+ ERG +E+ ER+
Sbjct: 380 QSAREREERERDRDRDRQKERERQTEKDRDGQRETEK-QREREKDRESERG-RERGRERE 437
Query: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
K++ + R R+ + + G ++ KR RT++ G + + R R R +
Sbjct: 438 KQKGRERDRERQTDRQAGRQR-KRSTLYVNPPPRTARSGVV---QSDPNRPTRGIRWKSS 493
Query: 152 EEREK--------------ERERKERKKRERKQVGEKEEERKEKER 183
E K R R ++R ++GEK + E R
Sbjct: 494 PEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRR 539
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 147 bits (371), Expect = 8e-36
Identities = 80/214 (37%), Positives = 146/214 (68%), Gaps = 15/214 (7%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
R+RER+ R++ +KER+ +RK R+RE+R++E+E R R+R EK+ E +++ K
Sbjct: 77 RQRERD-RVREKTEKERDRDRK---RDRERRRKEKETNRNRDR---EKQTEIERDREREK 129
Query: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE---ERE 155
++ RE+E G E+E+ + +EK ER R +++ ++ +R+ E +RE +ERE++KE ER+
Sbjct: 130 QKGRERERDRGRERERDRDREK-ERERQTEKDRDGQRETETERERDREREKQKERETERD 188
Query: 156 KERERKERKKRERKQVGEKEEERK-EKERKERKKRERNR---KERKKERERKERRERKKE 211
++R+R K+RER+ E++ +RK + ER+ RE R + R+++R+R +ER +E
Sbjct: 189 RDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRE 248
Query: 212 RKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
R +KEERKKER+K+R+ +EK++ ++ R+++K+
Sbjct: 249 RDRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
Score = 134 bits (336), Expect = 9e-32
Identities = 70/188 (37%), Positives = 130/188 (69%), Gaps = 8/188 (4%)
Query: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK-KEKKGERKKEER 95
E R +E+E ++ +K+ E ER +ER +++ R+RER++ R+RER + +EK+ ER+ E+
Sbjct: 101 ERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKD 160
Query: 96 ERKKRRREKENKEGEEKEKRKKKE-KKERGRTSKEGKERERKEERKRE-ERKERERKKEE 153
+R E E + E+EK+K++E +++R R KERER+ +R+R+ +RK + ++ E
Sbjct: 161 RDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRE 220
Query: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
++E ER+ ++RER +++ +R ++ +ER ++E +KERKKER +KER+E+KKE K
Sbjct: 221 TDREGERETDRRRER----QRDRDRGKERDRERDRKEERKKERKKER-KKERKEKKKEEK 275
Query: 214 KKEERKKE 221
++E++K++
Sbjct: 276 RREDKKRK 283
Score = 79.0 bits (193), Expect = 4e-15
Identities = 38/121 (31%), Positives = 80/121 (66%), Gaps = 6/121 (4%)
Query: 130 GKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKR 189
G + K+ + ++ER+R +E+ EKER+R ++ RER++ ++ +++E++ +R
Sbjct: 64 GLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIER 123
Query: 190 ERNRKERK-KERERKERRERKKERKKKEERKKERQKDRQ-----TNWREKERGKRERKER 243
+R R+++K +ERER RER+++R +++ER+++ +KDR RE++R + ++KER
Sbjct: 124 DREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKER 183
Query: 244 K 244
+
Sbjct: 184 E 184
Score = 68.2 bits (165), Expect = 6e-12
Identities = 33/101 (32%), Positives = 67/101 (66%), Gaps = 9/101 (8%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKRE------REKERKRERGKKEKKGERKK 92
R+R+R+ +T KE +++ + ER ++R+ + +R+RE RE +R+RER + +G+ +
Sbjct: 187 RDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERD 246
Query: 93 EERERK---KRRREKENKEGEEKEKRKKKEKKERGRTSKEG 130
ER+RK K+ R+KE K+ +++K+++K ++++ R EG
Sbjct: 247 RERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 287
Score = 48.9 bits (115), Expect = 4e-06
Identities = 23/76 (30%), Positives = 50/76 (65%), Gaps = 4/76 (5%)
Query: 171 VGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTN- 229
+G+ ++ +R+ + R R + E++++R+RK RER R+K++E + R +++QT
Sbjct: 65 LGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRER---RRKEKETNRNRDREKQTEI 121
Query: 230 WREKERGKRERKERKK 245
R++ER K++ +ER++
Sbjct: 122 ERDREREKQKGRERER 137
Score = 31.6 bits (70), Expect = 0.66
Identities = 14/37 (37%), Positives = 27/37 (72%), Gaps = 4/37 (10%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKR 71
+ E R++ER+ KE KKER+ ++K+E+R +K+++
Sbjct: 251 RKEERKKERK----KERKKERKEKKKEEKRREDKKRK 283
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 146 bits (369), Expect = 1e-35
Identities = 81/196 (41%), Positives = 131/196 (66%), Gaps = 10/196 (5%)
Query: 39 REREREIETRKEGKKERESERKKERREREK---RKREREKERKRERGKKEKKGERKKEER 95
+E+ER+ ++ ++ERE ER++ERRERE+ R+REREKE++RER ++ + + +ER
Sbjct: 298 KEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKER 357
Query: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE--- 152
+R + R +++ E R K + R ++ +ERER+ ER+RE +ERER++E
Sbjct: 358 DRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERER 417
Query: 153 EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE---RERKERRERK 209
ERE+ERER++ KKR+R++ E ER++ ERK R+K E +ER K RERK+ RE +
Sbjct: 418 EREREREREKDKKRDREEDEEDAYERRKLERKLREK-EAAYQERLKNWEIRERKKTREYE 476
Query: 210 KERKKKEERKKERQKD 225
KE +++EER++E K+
Sbjct: 477 KEAEREEERRREMAKE 492
Score = 143 bits (361), Expect = 1e-34
Identities = 85/230 (36%), Positives = 149/230 (64%), Gaps = 23/230 (10%)
Query: 37 EIREREREIETRKEGK--------KERESERKKERREREKRKREREKERKRERGKKEKKG 88
E+ E +R++ +R+ K +E + +++KER+E EK +RERE+ER+RER ++E++
Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERER 327
Query: 89 ERKKE-ERER-KKRRREKE-------NKEGEEKEKRKKKEKKERGRTSKEGKERERKEER 139
ER++E ERE+ K+R RE+E KE + R++ ++R R+S K+R R E+
Sbjct: 328 EREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREK 387
Query: 140 KREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK- 198
R+ +ERER++ ERE+ERER+ ++RER++ E+E ER++ ++++R++ E + ER+K
Sbjct: 388 SRDRERERERER-EREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKL 446
Query: 199 ERERKERRERKKERKKK---EERKKERQKDRQTNWREKERGKRERKERKK 245
ER+ +E+ +ER K ERKK R+ +++ RE+ER + KE K+
Sbjct: 447 ERKLREKEAAYQERLKNWEIRERKKTREYEKEAE-REEERRREMAKEAKR 495
Score = 134 bits (337), Expect = 7e-32
Identities = 71/198 (35%), Positives = 127/198 (64%), Gaps = 10/198 (5%)
Query: 53 KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK 112
KE + + E +R+ RE K R + +E+KG+++KE +E +K RRE+E + E+
Sbjct: 261 KEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERER 320
Query: 113 EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVG 172
E+R+++ ++ER R ++ KERER+ ER R+ R+R KE R+++R+R+ + R+R++
Sbjct: 321 ERREREREREREREREKEKERERERERDRD----RDRTKE-RDRDRDRERDRDRDRERSS 375
Query: 173 EKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWRE 232
++ ++R K R + +ER++ERER+ RER++ER+++ ER++ER+KD++ + E
Sbjct: 376 DRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREE 435
Query: 233 K-----ERGKRERKERKK 245
ER K ERK R+K
Sbjct: 436 DEEDAYERRKLERKLREK 453
Score = 132 bits (331), Expect = 4e-31
Identities = 77/231 (33%), Positives = 132/231 (57%), Gaps = 27/231 (11%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+ E RERERE E +E +KE+E ER++ER R +ER+++R RER + +
Sbjct: 319 ERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRN 378
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
++R + R + ++E E + +R+++ ++ER R + +ERER+ ER+RE+ K+R+R+++E
Sbjct: 379 KDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEE 438
Query: 155 EK-ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
+ ER + ERK RE++ +E K E +ERKK KE ++E ER RRE KE K
Sbjct: 439 DAYERRKLERKLREKE--AAYQERLKNWEIRERKKTREYEKEAEREEER--RREMAKEAK 494
Query: 214 KKEE----------------------RKKERQKDRQTNWREKERGKRERKE 242
+ +E R ++R+K+ + + R+++R K E +E
Sbjct: 495 RLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEE 545
Score = 129 bits (325), Expect = 2e-30
Identities = 76/230 (33%), Positives = 128/230 (55%), Gaps = 25/230 (10%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+S RE+ R+ E +E ++ERE ER++ER +R+RERE+ER+RE+ KK + E +++
Sbjct: 381 RSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDA 440
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE-- 152
ER+K R+ KE +E+ K E +ER +T + KE ER+EER+RE KE +R KE
Sbjct: 441 YERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFL 500
Query: 153 -----------------------EREKERERKERKKRERKQVGEKEEERKEKERKERKKR 189
+REKE E ER ++ K+ E+ +R E
Sbjct: 501 EDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDA 560
Query: 190 ERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRE 239
E R E++ ER R+ + +++ E +++EE K+E+++ R+ E+E +++
Sbjct: 561 ELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 83.2 bits (204), Expect = 2e-16
Identities = 57/208 (27%), Positives = 109/208 (52%), Gaps = 19/208 (9%)
Query: 50 EGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEG 109
E K ++++ R E E + + +R + KG + RE ++E
Sbjct: 171 EWKAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAP-SQES 229
Query: 110 EEKEKRKKKEKKER-------------GRTSKEGKERERKEERKREE-RKERERKKEERE 155
+ ++KKKEKKE +KE EE KR+ +E + ++ +
Sbjct: 230 DSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHK 289
Query: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215
K E K +K++ER+++ ++ ER+ + +ER++RER R ER++ERER++ +ER++ER++
Sbjct: 290 KLEEEKGKKEKERQEIEKERRERERERERERERRERER-EREREREREKEKERERERERD 348
Query: 216 EERKKERQKDRQTNWREKERGKRERKER 243
+R + +++DR R++ER + +ER
Sbjct: 349 RDRDRTKERDRD---RDRERDRDRDRER 373
Score = 48.1 bits (113), Expect = 7e-06
Identities = 41/195 (21%), Positives = 80/195 (41%), Gaps = 51/195 (26%)
Query: 98 KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKE 157
KK + + K + ++ K K+K G E + +E E ++ + K E
Sbjct: 155 KKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVL 214
Query: 158 RERKERKKRERKQVGEKEEERKEKERKE-------------------------------- 185
+ Q + +K+KE+KE
Sbjct: 215 IREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKR 274
Query: 186 ---------------RKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNW 230
+ + E+ +KE++++ KERRER++ER+++ ER +ER+++R+
Sbjct: 275 DLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERER-RERERERE--- 330
Query: 231 REKERGKRERKERKK 245
RE+ER K + +ER++
Sbjct: 331 REREREKEKERERER 345
Score = 35.4 bits (80), Expect = 0.045
Identities = 14/55 (25%), Positives = 35/55 (63%)
Query: 32 PGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEK 86
P +E++ E+E E R++ + ++E E ++E E+++++ +RE+ + E ++K
Sbjct: 556 PDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 145 bits (366), Expect = 3e-35
Identities = 73/198 (36%), Positives = 141/198 (71%), Gaps = 8/198 (4%)
Query: 39 REREREIETRKEGKKERESERKKERR-EREKRKREREKERKRERGKKEKKGERKKEERER 97
RER+RE + KE ++ER+ +R++E + ERE R R+R++ R+R+R +K +++ER+R
Sbjct: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64
Query: 98 KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE---ER 154
+ R+RE+E + E+++ ++++++ + +T +E ++++R ERKRE + RER ++ ER
Sbjct: 65 Q-RQRERETERETERQRERQRQRERKRQTDRE-RDKDRDRERKRETDRNRERNRKGGRER 122
Query: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
+K+ ER+ ++RER++ E+E +R ++ERK RER R ++ER+++ ++ERKKERK+
Sbjct: 123 DKQTERERDRERERQRQRERERQR-QRERKRETDRERQRWAEREERKKERKKERKKERKE 181
Query: 215 KEERKKERQKDRQTNWRE 232
K++ +K R++D++ W E
Sbjct: 182 KKKEEK-RREDKKRKWGE 198
Score = 138 bits (348), Expect = 4e-33
Identities = 73/188 (38%), Positives = 123/188 (65%), Gaps = 8/188 (4%)
Query: 58 ERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKK 117
ER++ER+ R +E E+ER R+R ++E + ER+ R+R R RE++ + EKE+ +
Sbjct: 2 ERQRERKRETDRGKETERERDRQR-ERENQTERENRHRQR-DRHRERDRQTDREKERER- 58
Query: 118 KEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEE 177
+KER R + +E ER+ ER+RE +++RERK R+ +RER + + RERK+ ++ E
Sbjct: 59 --QKERDRQRQRERETERETERQRERQRQRERK---RQTDRERDKDRDRERKRETDRNRE 113
Query: 178 RKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGK 237
R K +ER K+ ++R++ER+R+ RER+++R++K E +ERQ+ + R+KER K
Sbjct: 114 RNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKK 173
Query: 238 RERKERKK 245
+KERK+
Sbjct: 174 ERKKERKE 181
Score = 138 bits (347), Expect = 5e-33
Identities = 62/195 (31%), Positives = 137/195 (70%), Gaps = 5/195 (2%)
Query: 54 ERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKE 113
ER+ ERK+E ++ +RER+++R+RE + E++ ++ +R R++ R+ KE E ++
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERE-NQTERENRHRQRDRHRERDRQTDREKERERQK 60
Query: 114 KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGE 173
+R ++ ++ER + ++RER+ +R+R+ + +RER K +R++ER+R+ + RER + G
Sbjct: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDK-DRDRERKRETDRNRERNRKGG 119
Query: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK---KEERKKERQKDRQTNW 230
+E +++ + ++R++ + ++ER+++R+R+ +RE +ER++ +EERKKER+K+R+
Sbjct: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
Query: 231 REKERGKRERKERKK 245
+EK++ ++ R+++K+
Sbjct: 180 KEKKKEEKRREDKKR 194
Score = 134 bits (337), Expect = 7e-32
Identities = 73/207 (35%), Positives = 138/207 (66%), Gaps = 17/207 (8%)
Query: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR 101
ER+ E ++E + +E+ER+++R+ R+RE + ER+ ++++ ER ++ K+R
Sbjct: 2 ERQRERKRETDRGKETERERDRQ----RERENQTERENRHRQRDRHRERDRQTDREKERE 57
Query: 102 REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE-EREKERER 160
R+KE ++E+ ++E ER R + +ER+R+ +R+R++ ++RERK+E +R +ER R
Sbjct: 58 RQKERDRQRQRERETERE-TERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNR 116
Query: 161 KERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERK---ERRERKKERKKKEE 217
K ++R+++ E++ ER+ + ++ER+++ + ++R+ +RER+ ER ERKKERKK E
Sbjct: 117 KGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKK--E 174
Query: 218 RKKERQKDRQTNWREKERGKRERKERK 244
RKKER++ ++KE +RE K+RK
Sbjct: 175 RKKERKE------KKKEEKRREDKKRK 195
Score = 29.3 bits (64), Expect = 3.3
Identities = 17/36 (47%), Positives = 26/36 (72%), Gaps = 3/36 (8%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRK 70
+ E R++ER+ E +KE +KE++ E K RRE +KRK
Sbjct: 163 EREERKKERKKERKKE-RKEKKKEEK--RREDKKRK 195
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 144 bits (362), Expect = 9e-35
Identities = 69/207 (33%), Positives = 137/207 (66%), Gaps = 16/207 (7%)
Query: 55 RESERKKERR-EREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKE 113
R S +++R ER+ R + R+ +R G+++++ R++++R R + N E E E
Sbjct: 599 RSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDE 658
Query: 114 KRKKKE-------KKERGRTSKEGKERERKEERKREERKERERKKE-----EREKERERK 161
+R+++ + ER R +ER+R+ ER+RE ++RER+KE ER +ERER+
Sbjct: 659 RREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERERE 718
Query: 162 ERKKRERKQVGEKEEER---KEKERKERKKRERNRKERKKERERKERRERKKERKKKEER 218
K+R+R++ +++ +R +E+ER K+RER R+ER++ERER+ RER++ER+++ R
Sbjct: 719 REKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERAR 778
Query: 219 KKERQKDRQTNWREKERGKRERKERKK 245
+++++++RQ +W +K++G+ +R+E+++
Sbjct: 779 ERDKERERQRDWEDKDKGRDDRREKRE 805
Score = 132 bits (333), Expect = 2e-31
Identities = 73/216 (33%), Positives = 127/216 (58%), Gaps = 14/216 (6%)
Query: 26 SKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKE 85
S P G E+ ER E R + +R ER +ER +R RERE+ER+RER +
Sbjct: 642 SSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDR-- 699
Query: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
ER+KE ++R RE+E +R+K+ +ER R +ERER+ ER RE+ +
Sbjct: 700 ---EREKERELERERARERE-------REREKERDRERDRDRDHDRERERERERDREKER 749
Query: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER 205
ERER++ ERE+ERER+ ++RER++ +E +++ + +++ + +++ R +R+++RE E
Sbjct: 750 EREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKRE--EI 807
Query: 206 RERKKERKKKEERKKERQKDRQTNWREKERGKRERK 241
RE + R +ERK +++ + + ++ KR R+
Sbjct: 808 REDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRRE 843
Score = 130 bits (327), Expect = 1e-30
Identities = 77/230 (33%), Positives = 130/230 (56%), Gaps = 26/230 (11%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
RER+RE E +E ++ERE ER +ER + + +RER +ER+RER +KE+ ER ++ +
Sbjct: 677 RERDRERERDRERERERERERDREREKERELERERARERERER-EKERDRERDRDRDHDR 735
Query: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER 158
+R RE+E +E+E+ +++ ++ER R + +ERER+ ER RE KERER+++ +K++
Sbjct: 736 ERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDK 795
Query: 159 ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK----- 213
R +R+++ R+++ E R + ++ KKR RN + K RRE +
Sbjct: 796 GRDDRREK-REEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSG 854
Query: 214 --KKEERKKERQ----------------KDRQTNWREKERGKRERKERKK 245
K E+ + Q +DRQ W+E++R K ERKE +
Sbjct: 855 DDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDR-KPERKESSR 903
Score = 115 bits (289), Expect = 3e-26
Identities = 68/212 (32%), Positives = 116/212 (54%), Gaps = 17/212 (8%)
Query: 39 REREREIETRKEGKKERESERKKER-----------REREK-RKREREKERKRERGKKEK 86
RERE+E E +E +ERE ER+KER RERE+ R+R+REKER+RER ++E+
Sbjct: 699 REREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERER 758
Query: 87 KGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK----RE 142
+ ER++E ++R RE+ + +E+E+++ E K++GR + K E +E+R +
Sbjct: 759 ERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHD 818
Query: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
ERK ++R + E + +++RE + +K K R + R + +
Sbjct: 819 ERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSP 878
Query: 203 KERRERKKERKKKEERKKERQKDRQTNWREKE 234
E ++ R K+E+RK ER K+ + E+E
Sbjct: 879 SHLTEDRQGRWKEEDRKPER-KESSRRYEEQE 909
Score = 113 bits (282), Expect = 2e-25
Identities = 75/242 (30%), Positives = 132/242 (54%), Gaps = 36/242 (14%)
Query: 39 REREREIETRKEGKKERESERKKER-REREKRKREREKERKRERGKKEKKGERKKEERER 97
RER+R+ + +E ++ERE +R+KER RERE+R+RERE+ER+RER ++E++ ER +E +
Sbjct: 725 RERDRDRDHDRERERERERDREKEREREREERERERERERERER-ERERERERARERDKE 783
Query: 98 KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKE 157
++R+R+ E+K+ ++R+K+E+ R ++G + + ++R R E R+ +R +E
Sbjct: 784 RERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRRE 843
Query: 158 R----------ERKERKKRERKQVGEKEEERK------EKERKERKKRERNRKERKKERE 201
+ K K R QV +E R ++R+ R K E + ERK+
Sbjct: 844 HSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSR 903
Query: 202 RKERRERK-------KERKKKEERKKERQK-----------DRQTNWREKERGKRERKER 243
R E +E K K+R++ E + R + DR+T+ R + K++ K +
Sbjct: 904 RYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQ 963
Query: 244 KK 245
KK
Sbjct: 964 KK 965
Score = 102 bits (253), Expect = 4e-22
Identities = 68/230 (29%), Positives = 123/230 (53%), Gaps = 26/230 (11%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
++ +RE E R E + E SE R +R R R R E E+G + +G +
Sbjct: 531 RNHLREESSRTEIRNESRNESRSEI---RNDRMGRSRGRVPELP-EKGSRGSRGSQIDSH 586
Query: 95 RERKKRRREKENKEG-EEKEKRKKKEKKERGRTS---KEGKERERKEERKREERK----- 145
E + E+++ +++ +++ R S + ER+R++ R+R++R
Sbjct: 587 SSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIR 646
Query: 146 --------ERERKKEEREKER--ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195
ER+ ++EER +R +R++ + RER + E++ ER E+ER+ + RER KE
Sbjct: 647 HQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRER-ERERERERDRER-EKE 704
Query: 196 RKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
R+ ERER RER++E+++ ER ++R DR+ RE+ER + + +ER++
Sbjct: 705 RELERERAREREREREKERDRERDRDRDHDRERE-RERERDREKERERER 753
Score = 89.7 bits (221), Expect = 2e-18
Identities = 60/219 (27%), Positives = 103/219 (47%), Gaps = 13/219 (5%)
Query: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
+ R+RE RKE ES RE+ R + R + E + +R R
Sbjct: 506 DYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRG 565
Query: 97 RKKRRREKENK--EGEEKEKRKKKEK-KERGRTSKEGKERERKEERK-----REERKERE 148
R EK ++ G + + + T ER+R ER R+ ER
Sbjct: 566 RVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERR 625
Query: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERK--KRERNRKERKKERERKERR 206
+ +R RER +R + G +E +++ R+ER+ + + R ER +ER+R+ R
Sbjct: 626 HGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERER 685
Query: 207 ERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+R++ER+++ ER +ER+K+R+ E+ER + +ER+K
Sbjct: 686 DRERERERERERDREREKEREL---ERERAREREREREK 721
Score = 85.5 bits (210), Expect = 4e-17
Identities = 62/209 (29%), Positives = 104/209 (49%), Gaps = 30/209 (14%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRK-----REREKERKRERGKKEKKGERKKE 93
RERERE E +E +ER+ ER+++R +K K RE+ +E + +R ++ ERK +
Sbjct: 764 RERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSK 823
Query: 94 ERERK----------KRRREKE------NKEGEEKEKRKKKEKKERGRTSK--------E 129
+R R KRRRE N ++ EK + + R + S+ E
Sbjct: 824 KRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTE 883
Query: 130 GKERERKEERKREERKERERKKEERE-KERERKERKKRERKQVGEKEEERKEKERKERKK 188
++ KEE ++ ERKE R+ EE+E KE+ K+RE+ ++ E R + +
Sbjct: 884 DRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQS 943
Query: 189 RERNRKERKKERERKERRERKKERKKKEE 217
+R +R + +K+ + +KK KKK+E
Sbjct: 944 EDRETSDRAHDENKKKAKIQKKPIKKKKE 972
Score = 75.5 bits (184), Expect = 4e-14
Identities = 64/271 (23%), Positives = 111/271 (40%), Gaps = 68/271 (25%)
Query: 43 REIETRKEGKKERESERKKERREREKRKRE------------------------REKERK 78
R+ ++ ++ R+S ++ RE R+ R+ RK
Sbjct: 459 RDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRK 518
Query: 79 RERGKKEKKG---ERKKEERERKKRRREKENKEGEE-------KEKRKKKEKKERGRTSK 128
+ +E + +EE R + R E N+ E + + + E E+G
Sbjct: 519 EDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGS 578
Query: 129 EGK----------------------ERERKEER-----KREERKERERKKEEREKERERK 161
G ER+R ER R+ ER + +R RER
Sbjct: 579 RGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERD 638
Query: 162 ERKKRERKQVGEKEEERKEKERKERK------KRERNRKERKKERERKERRERKKERKKK 215
+R + G +E +++ R+ER+ +R+ +ER +ERER RER++ER++
Sbjct: 639 QRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERD 698
Query: 216 EERKKERQKDRQ-TNWREKERGKRERKERKK 245
ER+KER+ +R+ RE+ER K +ER +
Sbjct: 699 REREKERELERERAREREREREKERDRERDR 729
Score = 69.7 bits (169), Expect = 2e-12
Identities = 60/278 (21%), Positives = 115/278 (41%), Gaps = 68/278 (24%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
QS R ER +TR + +E++S ++E + + R+ +R+ G+ + ++
Sbjct: 408 QSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDR 467
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTS---------KEGKERERKEE------- 138
RE + R ++++E + + K+ + R S +EG++ RKE+
Sbjct: 468 RELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESR 527
Query: 139 -----RKREERKERERKKEEREKERE--RKERKKRERKQVGEKEEERKEKER-------- 183
REE E + E R + R R +R R R +V E E+ R
Sbjct: 528 SYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHS 587
Query: 184 ---------------------KERKKRERNR----KERKKERERKERRER---------- 208
ER R++ R + R ER+R++ RER
Sbjct: 588 SNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRH 647
Query: 209 --KKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
+ + +++ER++ER+ DR + R++ +R+R+ +
Sbjct: 648 QGRNDELERDERREERRVDRVDDRRDERARERDRERER 685
Score = 68.9 bits (167), Expect = 4e-12
Identities = 56/260 (21%), Positives = 116/260 (44%), Gaps = 37/260 (14%)
Query: 21 SCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRE 80
S S + + P +S +RE+ R R +R ER+++ R + R+++ +ER+ E
Sbjct: 378 SLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYE 437
Query: 81 RGKKEKKGER-KKEERERKKRRREKENKEGEE----KEKRKKKEKKERGRTSKEGKE-RE 134
+ + + R +E R+ + RR ++ ++ E ++ R +E ++ R +KE ++ R+
Sbjct: 438 QDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRD 497
Query: 135 RKEERKREERKERERKKEEREKERERKE---------RKKRERKQV-GEKEEERKEKERK 184
+ R + ++RE + R+++ +E R++ R ++ E E + + R
Sbjct: 498 SRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRN 557
Query: 185 ERKKRERNRKERKKERERK--------------------ERRERKKERKKKEER-KKERQ 223
+R R R R E+ + E R ER + ER +++
Sbjct: 558 DRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQA 617
Query: 224 KDRQTNWREKERGKRERKER 243
+D R ER +R+ +ER
Sbjct: 618 RDSSFERRHGERDRRDNRER 637
Score = 68.6 bits (166), Expect = 5e-12
Identities = 56/237 (23%), Positives = 106/237 (44%), Gaps = 23/237 (9%)
Query: 15 TELQMVSCSHIS-------KPCTQPGWQSEIREREREIETRKEGKKERESERKKERRERE 67
T ++ V H++ KP Q S R T + + ++
Sbjct: 1163 TRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQS 1222
Query: 68 KRKREREK-ERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRT 126
RKR R RE+ K + +K ++ KR + + ++ R ++ +
Sbjct: 1223 GRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPES 1282
Query: 127 SKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186
++ R + R+ +ER+R + +RE+ERER++ ++RE + +K+ R
Sbjct: 1283 DRQVHSRSGSFD-SRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPR-------- 1333
Query: 187 KKRERNR-KERKKERERKERRERKKERKK----KEERKKERQKDRQTNWREKERGKR 238
R+R+R +ER++ERER +RR+ +ER++ ER ++R +DR + E KR
Sbjct: 1334 -NRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKR 1389
Score = 66.6 bits (161), Expect = 2e-11
Identities = 56/243 (23%), Positives = 111/243 (45%), Gaps = 30/243 (12%)
Query: 31 QPGWQSEIREREREIETRKEGKKERE-----SERKKERRER-EKRKREREKERKRERGKK 84
Q W+ + + R+ E R+E +++R ERK ++R R E R+ ++R
Sbjct: 787 QRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSP 846
Query: 85 EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKER-GRTSKEGKERERKEERKREE 143
+ +++ K R + + E + ++R GR +E ++ ERKE +R E
Sbjct: 847 DSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYE 906
Query: 144 RKERERKKEEREKERERKERKKRERKQVGE-----KEEERKEKER---KERKKRERNRKE 195
+E + K +K+RE+ E + R + + + E+R+ +R + +KK + +K
Sbjct: 907 EQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKP 966
Query: 196 RKKERERKERRER---------------KKERKKKEERKKERQKDRQTNWREKERGKRER 240
KK++E ER KK +KKK KK ++ ++ ++E ++ +
Sbjct: 967 IKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSK 1026
Query: 241 KER 243
K+R
Sbjct: 1027 KKR 1029
Score = 63.2 bits (152), Expect = 2e-10
Identities = 39/187 (20%), Positives = 87/187 (46%), Gaps = 7/187 (3%)
Query: 64 REREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKER 123
R+REK K ++ R + K+GE + ++ R ++ + R+ +
Sbjct: 1233 RDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGS 1292
Query: 124 GRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKER 183
+ +ER+R E + ER+ R+ ++ E +++ ++ + R+R ++ E+E ER+ +R
Sbjct: 1293 FDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKR 1352
Query: 184 KERKKRERNRKERKKERERKERRERKKERKKKEERKK-------ERQKDRQTNWREKERG 236
++ + ER+R R+R E + E K+ E ++D ++ R+
Sbjct: 1353 RDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLAL 1412
Query: 237 KRERKER 243
+ER ++
Sbjct: 1413 DKERMDK 1419
Score = 61.2 bits (147), Expect = 8e-10
Identities = 57/242 (23%), Positives = 108/242 (44%), Gaps = 15/242 (6%)
Query: 5 ISSR---AAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKK 61
ISSR ++ + + +Q S S K P +Q + R R S
Sbjct: 327 ISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLR----RSASPYPSHSLSSP 382
Query: 62 ERREREKRKREREKERKR-ERGKKEKKGERKKEERE--RKKRRREKENKEGEEKEKRKKK 118
+R++ R R +E+ R + + + +R+ E RE R KR REK+++E E E+ +
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 442
Query: 119 EKKERG-RTSKEGKERERKEERKREERKERERKKEERE-KERERKERKKRERKQVGEKEE 176
+ R R ++G R+R++ R +R+E ++ R+ +E R +E + +
Sbjct: 443 SRDHRDDREPRDG--RDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRS 500
Query: 177 ERKEKERKERKKRERNRKE-RKKERERKERRERKKERKKKEERKKERQKDRQTNWREKER 235
R + ++R+ R+ +RKE E R R +E + E + E + + ++ R
Sbjct: 501 TRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRM 560
Query: 236 GK 237
G+
Sbjct: 561 GR 562
Score = 59.7 bits (143), Expect = 2e-09
Identities = 55/242 (22%), Positives = 102/242 (42%), Gaps = 20/242 (8%)
Query: 4 AISSRAAVKLNTELQMVSCSHISKPCTQPGWQSEI------REREREIETRK---EGKKE 54
A ++ AA +T +S S T + +E R R ++ET E +
Sbjct: 1121 ATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQH 1180
Query: 55 RESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE-KE 113
R+ +K + R R R R +++ +KR +++ E+ K
Sbjct: 1181 RKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKS 1240
Query: 114 KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERK----KRERK 169
E+K R K G E R R++ + ++ E +R+ R R+R
Sbjct: 1241 LEITGERKSRIDQLKRG-EPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRL 1299
Query: 170 QVGEKEEERKEKERKERKKRERN-----RKERKKERERKERRERKKERKKKEERKKERQK 224
Q ++ E +E+ER+ R R+R K+ + R+R RER++ER++ + R +R++
Sbjct: 1300 QERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRER 1359
Query: 225 DR 226
+R
Sbjct: 1360 ER 1361
Score = 56.6 bits (135), Expect = 2e-08
Identities = 45/209 (21%), Positives = 88/209 (42%), Gaps = 5/209 (2%)
Query: 36 SEIREREREIETRKEGKKERESERKKE--RREREKRKREREKERKRERGKKEKKGERKKE 93
S RE+ + +E E K + ++ E R R+ R +R + +++ +
Sbjct: 1232 SRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSG 1291
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
+ + R +E++ E + + +R++++ ++R K+ R +R R +ERER E
Sbjct: 1292 SFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERER---E 1348
Query: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
R+K R+ ++R E++ +R E + E ++ K ER R
Sbjct: 1349 RDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRD 1408
Query: 214 KKEERKKERQKDRQTNWREKERGKRERKE 242
K+ KD + +E K ER E
Sbjct: 1409 SLALDKERMDKDLGSVQGFEETNKSERTE 1437
Score = 55.8 bits (133), Expect = 3e-08
Identities = 37/186 (19%), Positives = 82/186 (44%), Gaps = 9/186 (4%)
Query: 67 EKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKK---KEKKER 123
E + + ++KR + R + + ++ G+++ RK+ ++R
Sbjct: 1176 EDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDR 1235
Query: 124 GRTSK---EGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180
+T G+ + R ++ KR E + + + +QV +
Sbjct: 1236 EKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDS 1295
Query: 181 KERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR-QTNWREKERGKRE 239
++R + + R + +ER ERER++ R+R+ +R ++ + R +DR + RE+ER KR
Sbjct: 1296 RDRLQERDRYEHDRER--ERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRR 1353
Query: 240 RKERKK 245
+R++
Sbjct: 1354 DLDRER 1359
Score = 53.5 bits (127), Expect = 2e-07
Identities = 45/176 (25%), Positives = 90/176 (51%), Gaps = 16/176 (9%)
Query: 16 ELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREK 75
E + +S SH+++ Q W+ E R+ ER KE + E + KE+ ++RE+ +
Sbjct: 872 ESRSLSPSHLTED-RQGRWKEEDRKPER-----KESSRRYEEQELKEKVSSVDKQREQTE 925
Query: 76 ERKRERGKKEKK-GERKKEERERKKRRREKENKEGEEKEKRKKKEKK-----ERGR---T 126
+ R + + G + E+RE R ++ K+ + ++K KK+K+ ERG T
Sbjct: 926 ILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETT 985
Query: 127 SKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKE 182
S++G+ K+ +K++ E++RKK + + + +E ++ +K+ G + KE
Sbjct: 986 SEDGQVFSPKKGQKKKS-IEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKE 1040
Score = 49.7 bits (117), Expect = 2e-06
Identities = 36/141 (25%), Positives = 69/141 (48%), Gaps = 4/141 (2%)
Query: 39 REREREIETRKEGKKERESERKKER-REREK-RKREREKERKRERGKKEKKGERKKEERE 96
RERERE ++ + +R++++ R R+R++ R+RERE+ER + R ++ + E
Sbjct: 1309 RERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVE 1368
Query: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
R + R E + E K+ E K G ++ + R +ER +++ + +
Sbjct: 1369 RDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFE 1428
Query: 157 ERERKERKKRERKQVGEKEEE 177
E + ER E + G+ E +
Sbjct: 1429 ETNKSER--TESLEAGDDESK 1447
Score = 48.5 bits (114), Expect = 5e-06
Identities = 46/248 (18%), Positives = 91/248 (36%), Gaps = 40/248 (16%)
Query: 35 QSEIREREREIETRKEGKKE------------RESERKKERREREKRKREREKERKRERG 82
+ E E+ EI +KE E R+S + +R+ K +K+RK
Sbjct: 181 EQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAV 240
Query: 83 KKEKKGERKKEERERKKRRREK---------ENKEGEEKEKRKKKEKKERGRTSKEGKER 133
+++ + + K++ + E+ +K K K K K +++GK+R
Sbjct: 241 SSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDR 300
Query: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKR---- 189
R ER+RE+R + + R Q G + R++R
Sbjct: 301 GRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQ 360
Query: 190 ---------------ERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234
+ ++++ R +E+ + + + + DR+ RE
Sbjct: 361 RTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDT 420
Query: 235 RGKRERKE 242
RGKR+R++
Sbjct: 421 RGKRDREK 428
Score = 47.8 bits (112), Expect = 9e-06
Identities = 49/203 (24%), Positives = 88/203 (43%), Gaps = 25/203 (12%)
Query: 57 SERKKERREREKRKREREKERKRERGKKEKKG---ERKKEERERKKRRREKENKEGEEKE 113
S R K +R ER RER K +++ E +K E KE+ G +E
Sbjct: 64 SPRGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHRE 123
Query: 114 KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE-------EREKERERKERKKR 166
K K KER + E +E + E R++ + + E ++++ ++E K
Sbjct: 124 KEDIKITKER---TPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKL 180
Query: 167 ERKQVGEKEEERKEKE---RKERKKRERNRKERKKERERKERRERKKERKKKEERKK--- 220
E++ + ++EE +KE R K + RK + K + K K++RK
Sbjct: 181 EQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAV 240
Query: 221 -----ERQKDRQTNWREKERGKR 238
++Q++ +TN + K++G R
Sbjct: 241 SSPLLDQQRNSKTN-QSKKKGPR 262
Score = 47.0 bits (110), Expect = 2e-05
Identities = 52/242 (21%), Positives = 98/242 (40%), Gaps = 40/242 (16%)
Query: 43 REIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR- 101
R R G + K++ + E +KR E+ R + + R+KE+ + K R
Sbjct: 75 RRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERT 134
Query: 102 --REKENKEGE-----------------EKEKRKKKEKKERGRTSKEGKERERKEE--RK 140
E+EN E E E K++K +R E + E++EE K
Sbjct: 135 PESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIK 194
Query: 141 REERKE-------------RERKKEEREKERERKERKKRERKQVGEK----EEERKEKER 183
+E E + K +R+ + K++RK +++R K
Sbjct: 195 KEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTN 254
Query: 184 KERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
+ +KK R E ++ KE+ K ++R +E+ +D + R+ ER +RE++++
Sbjct: 255 QSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFER-QREKRDK 313
Query: 244 KK 245
+
Sbjct: 314 PR 315
Score = 43.1 bits (100), Expect = 2e-04
Identities = 28/105 (26%), Positives = 54/105 (51%), Gaps = 6/105 (5%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+ +RERERE +E K R+ +R++ER + +R+R+++R R + + ++ E
Sbjct: 1337 RDRLRERERE----RERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEA 1392
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEER 139
+ + R+ E+ + K++ K+ G S +G E K ER
Sbjct: 1393 KLEGEHERDLESTSRDSLALDKERMDKDLG--SVQGFEETNKSER 1435
Score = 41.6 bits (96), Expect = 6e-04
Identities = 43/174 (24%), Positives = 74/174 (42%), Gaps = 16/174 (9%)
Query: 81 RGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK 140
RGK R+ ER R +NK + + +K+ +E +S KE R R+
Sbjct: 66 RGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEES--SSPVRKESSRGRHRE 123
Query: 141 REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER 200
+E+ K + + E E+E E R+ G+ + + E K+++ R+ K E+
Sbjct: 124 KEDIKITKERTPESEEENVEWETN-RDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQ 182
Query: 201 ERKERR---ERKKE------RKKKEE----RKKERQKDRQTNWREKERGKRERK 241
E E+R KKE R K RK + R+++ + K++RK
Sbjct: 183 ENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRK 236
Score = 40.0 bits (92), Expect = 0.002
Identities = 37/162 (22%), Positives = 71/162 (43%), Gaps = 23/162 (14%)
Query: 35 QSEIRERER----------EIETRKEGKKERESERKKERREREKRKREREKERKRERGKK 84
Q+EI E R + E R+ + + +KK + +++ K+++E + ERG
Sbjct: 923 QTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNI 982
Query: 85 E-----------KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
E KKG++KK KKR++ K + + ++E ++ +KK RT +
Sbjct: 983 ETTSEDGQVFSPKKGQKKKSIE--KKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKE 1040
Query: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKE 175
E E + + +K+E + + +R +V E E
Sbjct: 1041 ELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAE 1082
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 135 bits (339), Expect = 4e-32
Identities = 72/194 (37%), Positives = 128/194 (65%), Gaps = 8/194 (4%)
Query: 39 REREREIETRKEGKKERESERKKERREREK-RKREREKERKRERGKK-EKKGERKKEERE 96
RER RE + ++ KE ++E + R+R++ R+R RE++R RER K+ +++GER++E
Sbjct: 21 RERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERER 80
Query: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE-ERE 155
+ R+RE E + +E+E + E +R R ++ +E ER +R+RE++KE R+++ +RE
Sbjct: 81 DRDRQRETERERDKERETDRHTET-DRERQKQKEREMERVRDREREKQKEMGRERQTDRE 139
Query: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER----KERRERKKE 211
+RER+ + +RER+ E++ E + +ER+ +KRER RK KERER + R+R+ +
Sbjct: 140 TDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETD 199
Query: 212 RKKKEERKKERQKD 225
RK+ +R+ ER++D
Sbjct: 200 RKRDRQRESERERD 213
Score = 126 bits (316), Expect = 2e-29
Identities = 68/213 (31%), Positives = 133/213 (62%), Gaps = 13/213 (6%)
Query: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR 101
E + E R + +R++ERR R+R+R KE K E E+ +R +E + R
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
Query: 102 REKENKEGEEKEKRKKKEK-KERGRTSKEGKERERKEERKREERKERERKKE---EREKE 157
RE+E + E E+++++E+ ++R R ++ +++ER+ +R E +ER+++KE ER ++
Sbjct: 62 REREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRD 121
Query: 158 RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEE 217
RER+++K+ R++ ++E +R E+ER+ ++RE R+ + ++R R+ RERK+ER++K E
Sbjct: 122 REREKQKEMGRERQTDRETDR-ERERQAERERETGRERKTEDRHRERERERKRERERKRE 180
Query: 218 RKK-------ERQKDRQTNWREKERGKRERKER 243
K+ ER++ R+T+ R+++R + +ER
Sbjct: 181 TKERERHTDMERERQRETD-RKRDRQRESERER 212
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 128 bits (322), Expect = 4e-30
Identities = 60/222 (27%), Positives = 152/222 (68%), Gaps = 7/222 (3%)
Query: 31 QPGWQSEIREREREIET--RKEGKKERESERKKERREREKR--KREREKERKRERGKKEK 86
+P Q E++E E ++ R+E ++ER+ E ++++R R ++ +R++E+ER+ ++ ++ +
Sbjct: 264 EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE 323
Query: 87 KGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKE 146
+ ER++++ ER++++ +E +E E++ R+++E++ R + + +E ER+E++ R E++
Sbjct: 324 QQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL 383
Query: 147 RERKKEEREKERERKERKKRERKQVGEKEEERKEKERKE---RKKRERNRKERKKERERK 203
R ++ RE++ R+++ +RE++ E++ R+++ R+E R+++E R E+K E+ER+
Sbjct: 384 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443
Query: 204 ERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
E+R ++++ ++++ K+E + +R R K++ KR+++E ++
Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR 485
Score = 126 bits (316), Expect = 2e-29
Identities = 64/228 (28%), Positives = 154/228 (67%), Gaps = 19/228 (8%)
Query: 35 QSEIREREREIETRKEGKKERESERKK-------ERREREKRKRE---REKERKRERGKK 84
+ ++R RE +E R++G++E++ +R++ E E+E RKRE R++E K + +
Sbjct: 207 EEQLRRREL-LELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
Query: 85 EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER 144
+++ E ++EE + +K R++ +E +E+E+++++ ++E+ K+ +ER ++E +RE++
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 145 KERERKKEEREKERERKERKKRERKQVGEKEEERKE----KERKERKKRERNRKERKKER 200
+ RE+++E RE++ R++ ++RE++ E+EEER+E +E++E ++ ++ R+E++ R
Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
Query: 201 ERKERRE----RKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
E++ RRE R+++ +++++ ++E+Q R+ R +++ +RE++E +
Sbjct: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEER 433
Score = 126 bits (316), Expect = 2e-29
Identities = 66/221 (29%), Positives = 151/221 (68%), Gaps = 16/221 (7%)
Query: 41 REREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER-KKEERERKK 99
RE+++ ++ ++E++ R+++ R ++ +RE+E+ER ++ ++E++ +R K+E+ ER+
Sbjct: 397 REQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRD 456
Query: 100 RRREKENKEGEEKEKRK-------KKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
+ +E E E+E+RK ++E++ER +E + RE++E R+++ R+E+E ++E
Sbjct: 457 WLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERRE 516
Query: 153 E---REKERERKERKKRERKQVGEKEEERKEK--ERKERKKRERNRKERKKERERKERRE 207
+ R++E ER +++ R +Q+ ++EER+E+ +R+E K+ E+ R+E++ +RE++ERR+
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 208 R--KKERKKKEERKKERQKDRQTNWREKERGKR-ERKERKK 245
+ K+E +++++R K Q++R ++E +R E++ER++
Sbjct: 577 QLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRE 617
Score = 126 bits (316), Expect = 2e-29
Identities = 72/219 (32%), Positives = 142/219 (64%), Gaps = 9/219 (4%)
Query: 35 QSEIRER--EREIETRKEG-KKERESERKKERREREKRKREREKERKRERGKKEKKGERK 91
+ E RE+ +RE E R++ K+E E+ER ++ R +++ KR++E+ER+ K E++ R+
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498
Query: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
++ER ++ RRE+E + E++ KR+++E++ + R E + R +EER+ + K E K+
Sbjct: 499 QQERREQQLRREQEERR-EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKR 557
Query: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER-ERKERRERKK 210
E+E+ +R +R++ ER+ K EE + ++R +R++ ER + K+E ER E+ ER++
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRE 617
Query: 211 ERKKKEERKKERQ----KDRQTNWREKERGKRERKERKK 245
+R K+EE ++ER+ K + R +++ +RE++ER++
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656
Score = 126 bits (316), Expect = 2e-29
Identities = 72/242 (29%), Positives = 157/242 (64%), Gaps = 24/242 (9%)
Query: 26 SKPCTQPGWQSE---IREREREIETRKEGKKERESERKKERREREKRKREREKERKRERG 82
+KP Q + E ++E E E++ R+E +K R E++++ RE E+ ++E E+ + ER
Sbjct: 891 AKPALQEQLRKEQQLLQEEEEELQ-REEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKE------RERK 136
K+ ++ ER+++ R+ KK ++++E GEE EKR+++E++++ R +E ++ RE +
Sbjct: 950 KRRRQ-ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREER 1008
Query: 137 EERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE------ 190
E+R+R+E + + RKK+E ++E E+ R++RE++++ E+E + +E+E ++++ +
Sbjct: 1009 EKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEER 1068
Query: 191 --RNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRE-----RKER 243
R R+E +++ ++E ++++E+ +EE +K R+++R+ RE+E ++E R+ER
Sbjct: 1069 ETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREER 1128
Query: 244 KK 245
+K
Sbjct: 1129 EK 1130
Score = 125 bits (313), Expect = 4e-29
Identities = 60/209 (28%), Positives = 139/209 (66%), Gaps = 1/209 (0%)
Query: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERG-KKEKKGERKKEER 95
E E RE + R+E + RE + ++E++ R +++ RE++ +RE+ ++E++ R+++ R
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
++ R ++ E E +E+R K+E++ER K +E ER E+ +R+++ +R++++E RE
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
Query: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215
+ + +E ++RE+++ E++ R+++ER+E++ + + +ER ++R R E++ R+++ +++
Sbjct: 487 RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 216 EERKKERQKDRQTNWREKERGKRERKERK 244
E+ K ++ R R ++R KRE++ER+
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERR 575
Score = 124 bits (311), Expect = 7e-29
Identities = 60/220 (27%), Positives = 147/220 (66%), Gaps = 10/220 (4%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+ E + +E E + ++E ++E E RK ER+E + ++E E++++R R +++ + ++++E
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
RE+++ RRE++ + +++E+R+++ ++E+ ++ RE++EER RE++ RE+++E R
Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER-REQQLRREQEEERR 373
Query: 155 EKERERKERKKRERKQVGEKEEERKEKERKE---------RKKRERNRKERKKERERKER 205
E++ R+++ +RE++ E++ R+++ R+E R++++ R+++ + + +ER
Sbjct: 374 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEER 433
Query: 206 RERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
E+K E++++E+R K Q++R+ + +E +R +ER+K
Sbjct: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK 473
Score = 122 bits (307), Expect = 2e-28
Identities = 63/215 (29%), Positives = 149/215 (69%), Gaps = 7/215 (3%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+ E R+RE + +E +E E +R++E +E E++ R+ E++ R R ++E++ ++++
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELR-RERQEEEQQQQRLR 301
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
RE++ RR+++E + +++E+R+++E++E+ +E + R +EER RE++ RE+++E R
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEER-REQQLRREQEEERR 360
Query: 155 EKERERKERKKRERKQVGEKEEERKEKE--RKERKKRERN-RKERKKERERKERRER--K 209
E++ R++ ++R +Q+ +++ R+E++ R+++ +RE+ R+E++ RE++ RRE+ +
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 210 KERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
+E++ + E+++ER + + R ++R KRE++ER+
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
Score = 122 bits (306), Expect = 3e-28
Identities = 64/219 (29%), Positives = 149/219 (68%), Gaps = 14/219 (6%)
Query: 39 REREREIETRKEGKKERESERKKE--RREREKRKREREKERKRERGKKEKKGERKKEERE 96
RER+ E + ++ ++E++ RK+E RRE+++ +RE+++ R+++ ++E++ R++EER
Sbjct: 288 RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR 347
Query: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERE----RKEERKREERKERERKKE 152
++ RRE+E + E++ +R+++E++ + +E + R R+E++ R E++ R ++
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 407
Query: 153 EREKERERKERKKRERKQVGEKEEERKEKE-----RKERKKRERNRKERKKERERKERRE 207
RE++ R+++ +RE++ E+EEER E++ R++R KRE ++ER+ +R+E E
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE--QEERRDWLKREEETE 465
Query: 208 RKKERKKKEERKKERQKDRQTNW-REKERGKRERKERKK 245
R ++ ++K++ K++++++R+ W + +E +RE++ER++
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE 504
Score = 122 bits (305), Expect = 4e-28
Identities = 64/238 (26%), Positives = 148/238 (62%), Gaps = 27/238 (11%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Q E R ++E ++E ++E++ R++E R ++ +RE+E+ER+ ++ ++E++ ER++++
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ 376
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKE----------------RGRTSKEGKERERKEE 138
R+++ R ++ E++ +R+++ ++E R + + +E ER E+
Sbjct: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQ 436
Query: 139 RKREERKERERKKEE--------REKERERKERKKRERKQVGEKEEERKE---KERKERK 187
+ +ER+E+ K+E+ RE+E ER E+++R+++ ++EEER+E K +E +
Sbjct: 437 KHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEER 496
Query: 188 KRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+ ++ R+E++ RE++ERRE++ +R+++EER ++R + Q RE+E + + +R++
Sbjct: 497 REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE 554
Score = 122 bits (305), Expect = 4e-28
Identities = 69/217 (31%), Positives = 142/217 (65%), Gaps = 8/217 (3%)
Query: 35 QSEIRER--EREIETRKEGKKERESERKKERREREKR--KREREKERKRERGKKEKKGER 90
+ E RER + E E R+E ++ RE + ++E+ ER ++ KR+ E+ER ++R + E++ R
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR 540
Query: 91 KKEERERKKRRREKENK-EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
++EER + +RE+E + E E +E+R K+E++ER + +E R++ KRE+ + E+
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600
Query: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERK 209
+ + E ER +E ++ +R + E EEER+++ K ++ E R++++ RE++ERRE++
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE--RRQQQLRREQQERREQR 658
Query: 210 KERKKKEERKKER-QKDRQTNWREKERGKRERKERKK 245
+R+++EER ++R +++ + RE+E + E+++ ++
Sbjct: 659 LKREEEEERLEQRLKREHEEERREQELAEEEQEQARE 695
Score = 120 bits (300), Expect = 1e-27
Identities = 69/226 (30%), Positives = 137/226 (60%), Gaps = 16/226 (7%)
Query: 35 QSEIREREREIETRKEGKKERESERKKE---RREREKRKREREKERKRERGKKEKKGERK 91
Q E RE+ R E ++ ++E + ++++E R EREKR+R+ + + R+ K ++K E+
Sbjct: 914 QREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL 973
Query: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK- 150
E K+RR+E+E K EE+E ++++E+ R K ++ ++ RK++E ++ E +
Sbjct: 974 LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL 1033
Query: 151 -KEEREKER-ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE--------- 199
+EEREK R + +ER+ RE +++ ++EE+ +ER+ R+++E R+ RK+E
Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093
Query: 200 -RERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
RE E+R R++ ++ E ++ +Q++ Q E+E+ +R+ ER+
Sbjct: 1094 LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ 1139
Score = 119 bits (299), Expect = 2e-27
Identities = 69/228 (30%), Positives = 141/228 (61%), Gaps = 21/228 (9%)
Query: 39 REREREIETRKEGKKERESERKKERREREKR-KREREKER----KRERGKKEKKGERKKE 93
++ RE E R+E +RE E++ E+ RE+R KRE+E+ R KRE +++++ +R++E
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE 595
Query: 94 ER-ERKKRRREKENKEGEEKE----KRKKKEKKERGRTSKEGKERERKEERKREERKERE 148
ER E++ +R E E E EE+ KR++ E++ R + K ++ ER++++ R E++ER
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR---------KERKKE 199
++ +RE+E ER E++ + + +E+E E+E+++ ++R ++R E
Sbjct: 656 EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR 715
Query: 200 RERKERRERKKE--RKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+ + R RK+E R+++E+ +K R+++ + W+E+ER R+++E ++
Sbjct: 716 QSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763
Score = 119 bits (298), Expect = 2e-27
Identities = 66/216 (30%), Positives = 142/216 (65%), Gaps = 12/216 (5%)
Query: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE-RERK 98
+R++E E R+ K E ER++++ RE++ R ++ER+ +R K++++ ER ++ R +
Sbjct: 477 KRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ 536
Query: 99 KRRREKENKEGE----EKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
+ RRE+E + + E+EKR ++E++E+ R +E +ER + ++ EER+++ K+E+
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQ-RLKREQEERRDQLLKREEERRQQRLKREQE 595
Query: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRER-----NRKERKKERERKERRERK 209
E+ +R +R++ ER + E+ E+R ++E E ++R++ ++ER++++ R+E++ER+
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 210 KERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
++R K+EE ++ER + R E+ER ++E E ++
Sbjct: 656 EQRLKREE-EEERLEQRLKREHEEERREQELAEEEQ 690
Score = 118 bits (296), Expect = 4e-27
Identities = 52/213 (24%), Positives = 144/213 (67%), Gaps = 3/213 (1%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+ E RE++ E ++E ++++E R+++ R ++ +RE++ R++E ++E++ R++EE
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
R+++ R ++ E++ +R+++ ++E+ ++ RE++ R+++ R+E++ ++E+
Sbjct: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430
Query: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKER-- 212
E+ E+K ++R +++ ++EER++ ++E ++ ER+ +ER+K++ ++++ E ++ER
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKRE-EETERHEQERRKQQLKRDQEEERRERWL 489
Query: 213 KKKEERKKERQKDRQTNWREKERGKRERKERKK 245
K +EE ++E+Q+ R+ R ++ +RE++ +++
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQ 522
Score = 117 bits (292), Expect = 1e-26
Identities = 66/231 (28%), Positives = 146/231 (63%), Gaps = 27/231 (11%)
Query: 39 REREREIETRKEGKKERESER----KKERREREKRKREREKERKRERGKKEKKGE----R 90
R +E+E + R+E + ++E E+ ++E+R R++R+R+ K++K ++ +++ GE R
Sbjct: 922 RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKR 981
Query: 91 KKEERERKKRRREKENKE-----GEEKEKRKKKE-----------KKERGRTSKEGKERE 134
+++ERE+K R E+ +E EE+EKR+++E ++E + +E +E+
Sbjct: 982 RRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKR 1041
Query: 135 RKEERKREERKERERKKEERE---KERERKERKKRERKQVGEKEEERKEKERKERKKRER 191
R +ER+R+ R+E E ++EE + +ERE + R++ ER+ E+E +++E++ + +R
Sbjct: 1042 RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101
Query: 192 NRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
R+ER+++ +E ++++E+ +EER+K R+++ + +RE+E ++E ++
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQ 1152
Score = 116 bits (291), Expect = 2e-26
Identities = 64/223 (28%), Positives = 147/223 (65%), Gaps = 15/223 (6%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+ E+++ E ++ R+E +K R E +++ R++++ ++E E+ + ER K+ + ER+++
Sbjct: 993 EEELQQEEEQL-LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ-ERERQY 1050
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKE------RERKEERKREERKERE 148
RE ++ ++E+E GEE+E R+++E + + R +E ++ RE E+R+R+ER+ +
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC 1110
Query: 149 RKKEEREKERE---RKERKKRER----KQVGEKEEERKEKERKERKKRERNRKERKKERE 201
R++EE ++E E R+ER+KR R +Q E+EE ++E+E+ R++ E+ R++ + +
Sbjct: 1111 REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 202 RKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
R+E +++E + E +++R+++R+ +RE+E +R++++++
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213
Score = 116 bits (290), Expect = 2e-26
Identities = 65/219 (29%), Positives = 140/219 (63%), Gaps = 8/219 (3%)
Query: 35 QSEIREREREIETRKEGKKERESER--KKERREREKRKREREKERKRERGKKEKKGERKK 92
++E E+ER + K ++E ER K E ER +++ RE++ +RE+ ++ ++ +++
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQ 522
Query: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER-ERKK 151
EE ER ++R E + E+E+R+++ K E + RE++ +R++EER+++ +++
Sbjct: 523 EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKRE 582
Query: 152 EEREKERERKERKKRERKQVGEKEEERKEKE--RKERKKRERNRKERKKE---RERKERR 206
EER ++R ++E+++R +++ +E ER E+E R++R KRE +ER+++ E +E R
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
Query: 207 ERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+++ R++++ER+++R K + R ++R KRE +E ++
Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR 681
Score = 116 bits (290), Expect = 2e-26
Identities = 68/242 (28%), Positives = 146/242 (60%), Gaps = 31/242 (12%)
Query: 34 WQSEIR--EREREIETRKEGKKERESERKKERRE---------REKRKREREKERKRERG 82
WQ E R +++E E R++ + ++E K ER RE+R+R+ E +++R
Sbjct: 748 WQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQRE 807
Query: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142
++ E +KE+R R++R REKE + EE+E+ +++E+ ++ + ++G + +++ R +E
Sbjct: 808 QRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867
Query: 143 ERKERE-RKKEEREKERER---------KERKKRERKQVGEKEEERKEKERKERKKRERN 192
+R++++ R + E E++R R +E+ ++E++ + E+EEE + +ER++R+++E+
Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927
Query: 193 RKERKKE----------RERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
R+ R++E RE +E+R R++ ++ + KK +QK+ Q E E+ +R+ +E
Sbjct: 928 RQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
Query: 243 RK 244
+K
Sbjct: 988 KK 989
Score = 116 bits (290), Expect = 2e-26
Identities = 72/231 (31%), Positives = 149/231 (64%), Gaps = 27/231 (11%)
Query: 39 REREREIETRKEGKKERESER-------KKERREREKRKREREK-ERKRERGKKEKKGER 90
R +ERE + RK+ K +++ E+ K+ R+EREK+ RE E+ +++ E+ +E++ +R
Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011
Query: 91 KKEERERKKRRREKENKEGE-----EKEKRKKKEKKERGRTSKE---------GKERE-- 134
+++E ER+ R++++ +E E E+EKR+ +E++ + R +E G+ERE
Sbjct: 1012 RRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETR 1071
Query: 135 RKEERKREERKERERKKEEREKERERKERKKRE--RKQVGEKEEERKEKERKERKKRE-R 191
R++E +R+ RKE E ++EE + RE E+++R+ +Q E+EE ++E+E+ R++RE R
Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
Query: 192 NRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
R+E +++ +E ++++E+ +EE +K R+++ + +RE+E ++E ++
Sbjct: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182
Score = 115 bits (289), Expect = 3e-26
Identities = 65/229 (28%), Positives = 143/229 (62%), Gaps = 20/229 (8%)
Query: 35 QSEIRERE--REIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
+ E RE++ RE + R+E + RE + ++E++ R +++ RE++ +RE+ + ++ R++
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428
Query: 93 EERERKKRRREKENKEG----EEKEKR---KKKEKKERGRTSKEGKERERKEERKREER- 144
+E ER +++ E+E +E E++E+R K++E+ ER + ++ +R +E +R ER
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488
Query: 145 -----KERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER--- 196
+ER ++E RE++ R++ ++RE++ ++EEER ++ + ++ R ++ER
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548
Query: 197 --KKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
K+E E++ +ER+++R K+E+ ++ Q ++ R ++R KRE++ER
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Score = 115 bits (287), Expect = 5e-26
Identities = 68/224 (30%), Positives = 138/224 (61%), Gaps = 17/224 (7%)
Query: 36 SEIREREREIETRKEGKKERESERKKERR----------EREKRKREREKERKRERGKKE 85
S++R+R+ + + + +++E +R++ERR E E+ +RE +KE KR K +
Sbjct: 1256 SQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQ 1315
Query: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
++ + +EERE K+RR+E + K EE++ +++E++ R ++ K RE + + + RK
Sbjct: 1316 EEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRK 1375
Query: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER 205
E ++ R +ERERK K E +Q+ +E E++ ++ ++RK RE ++ ++ER+RK R
Sbjct: 1376 FLEEEQRLRRQERERKFLK--EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFR 1433
Query: 206 RERKKERKKKEERK-----KERQKDRQTNWREKERGKRERKERK 244
E ++ R+++ ERK ++ +++R +RE+E+ +ER+E++
Sbjct: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ 1477
Score = 114 bits (286), Expect = 6e-26
Identities = 60/224 (26%), Positives = 145/224 (64%), Gaps = 16/224 (7%)
Query: 35 QSEIREREREIETRKEGKKE-RESERKKERREREKRKREREKERKRERG---------KK 84
Q + RER ++++ ++G +E +E R +E+R +K + + E+ERKR R ++
Sbjct: 839 QLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQ 898
Query: 85 EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK---ERGRTSKEGKERERKEERKR 141
+K ++ +E E + +R E+E + +E+E++ ++E++ E + +E +E+ R++ER+R
Sbjct: 899 LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERER 958
Query: 142 EERKERERKKEERE---KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK 198
+ RK+++ +++E + +E E++ R++RE+K E+E +++E++ ++ +R R+E ++
Sbjct: 959 QYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER 1018
Query: 199 ERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
+ +K+ ++++E+ +EER+K R ++R+ +RE+E ++E ++
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ 1062
Score = 113 bits (282), Expect = 2e-25
Identities = 69/235 (29%), Positives = 148/235 (62%), Gaps = 29/235 (12%)
Query: 37 EIREREREIETRKEGKK--ERESERKKER-------------REREKRKREREKERKRER 81
E +ER R E R++ K + E ERK+ R R+ ++ +E E+E +RE
Sbjct: 858 EDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREE 917
Query: 82 GKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERK----- 136
+K ++ E++++ RE ++ ++E+E EE+EKR+++E++ + R K+ +++E +
Sbjct: 918 REKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977
Query: 137 -EERKREERKERERKKEEREKERE---RKERKKRER----KQVGEKEEERKEKERKERKK 188
E+R+R+ER+++ R++EE ++E E R+ER+KR R +Q +K+E ++E+E+ R++
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 189 RERNR-KERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
RE+ R +ER+++ +E ++++E+ EER+ R+++ + +R++E ++E ++
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQ 1092
Score = 112 bits (281), Expect = 2e-25
Identities = 67/243 (27%), Positives = 154/243 (63%), Gaps = 29/243 (11%)
Query: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90
+PG + + +E+E E EG+++ E + + E+R+R++R E ++R+ + ++E++ E
Sbjct: 132 EPGQRRRQKRQEQERELA-EGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEE 190
Query: 91 KKEER-----------ERKKRRRE-----KENKEGEEKEKRKKKEKKERGRTSKEGKERE 134
++ + E + RRRE ++ +E +++++R+++++ + KE ++RE
Sbjct: 191 EQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRE 250
Query: 135 ---RKEERK-REERKERERKKEEREKERERKERKK-RERKQVGEKEEERKEKERKERKKR 189
RKEE K +EE +R+R+ +E E++ + ER++ R +Q E++++R +E++ R+K+
Sbjct: 251 TVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310
Query: 190 ERNRKERKKER-ERKERRERKKERKKK------EERKKERQKDRQTNWREKERGKRERKE 242
E R+E+++ER E++ERRE+++ER+++ EER++++ + Q R +++ +RE++E
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
Query: 243 RKK 245
++
Sbjct: 371 ERR 373
Score = 112 bits (281), Expect = 2e-25
Identities = 62/225 (27%), Positives = 138/225 (61%), Gaps = 19/225 (8%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
RERE+E++ +E ++ + ER ++ +E E +E ++ R+ + ++++K + EE ERK
Sbjct: 825 REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEE-ERK 883
Query: 99 KRR-------------REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
+RR R+++ EE+E+ +++E+++R R +E + RE ++ ++ EE+
Sbjct: 884 RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQL 943
Query: 146 ERERKKEEREKERERKERK-----KRERKQVGEKEEERKEKERKERKKRERNRKERKKER 200
RE +++ R +ERER+ RK ++E + +GE+ E+R+ +ER+++ + E ++ +++
Sbjct: 944 LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL 1003
Query: 201 ERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
R+ER +R+++ +++ RKK+ + + +ER KR +ER++
Sbjct: 1004 LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERER 1048
Score = 112 bits (281), Expect = 2e-25
Identities = 75/245 (30%), Positives = 150/245 (61%), Gaps = 38/245 (15%)
Query: 37 EIREREREIETRKEGKKER---ESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
E +ER+RE E R+ +++R E E+ + ++E ++R+R+ + +++ ++E++ +R+++
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332
Query: 94 ERERKKRRREKENKEGEE----KEKRKKKEKKERGRTSKEGK------------ERERK- 136
E +RK R E+ +E EE +++R +K ++E R ++G+ ERERK
Sbjct: 1333 ETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKF 1392
Query: 137 ---------EERKREERKERERKKEEREKERERKERKKR---ERKQVGEKEEERKEKERK 184
+ER+++ R++R+RK E E++ R+ER ++ E +QV +E ERK E +
Sbjct: 1393 LKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452
Query: 185 ERKKRERNRKERKKE---RERKERRERKKERKKK--EERKKERQKDRQTNWREKERGKRE 239
++ ++ER+RK R++E +ER+E++ ++ER +K EE ++ R+++R +RE+E +E
Sbjct: 1453 QQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
Query: 240 RKERK 244
ERK
Sbjct: 1513 -PERK 1516
Score = 112 bits (281), Expect = 2e-25
Identities = 68/246 (27%), Positives = 153/246 (62%), Gaps = 14/246 (5%)
Query: 12 KLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKR 71
K E Q + C + Q + RE E+++ ++ +K RE E++ R+ERE++
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDR-DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFL 1449
Query: 72 EREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKE-- 129
E E++ ++ER +K ++ E+ +ERE ++ R++ +++ E+E++ ++++++R +E
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509
Query: 130 GKERERK--EERKREERKERERKKEEREKERERKERKKRER----KQVGEKEEERKEKER 183
+E ERK EE ++ R++R+RK + E++ R+ER ++ R ++ E+E+ R+E+E
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569
Query: 184 KERKKRERNRK----ERKKERERKERRERKKERK-KKEERKKERQKDRQTNWREKERGKR 238
++ ++ER+RK E+K R+ +ER+ + E++ +++E +++ +++R +RE E+ +
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Query: 239 ERKERK 244
ER+E++
Sbjct: 1630 EREEQQ 1635
Score = 112 bits (280), Expect = 3e-25
Identities = 68/226 (30%), Positives = 138/226 (61%), Gaps = 18/226 (7%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+ ++ ERE R+E +++ ++K +++E + E EK R++ER KK ++ E ++E
Sbjct: 940 EEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQE 999
Query: 95 RERKKRR-REKENKEGEEKEKRKKKE-KKERGRTSKEGKERERKEERKREERKERERKKE 152
E+ R REK ++ E++ RKK E ++E + +E +E+ R +ER+R+ R+E E ++E
Sbjct: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQE 1059
Query: 153 ERE--------KERERKERKKRERKQVGEKEEE--RKEKERKERKKRE---RNRKERKKE 199
E + + R+ ER+ R+ +++ ++EE+ R+E E++ R++RE R +E ++E
Sbjct: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119
Query: 200 RERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
E+ R ER+K R+++ ER+ +++ Q +E+E+ RE E+++
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEEVQ---QEEEQLLREEPEKRR 1162
Score = 112 bits (279), Expect = 4e-25
Identities = 67/228 (29%), Positives = 141/228 (61%), Gaps = 19/228 (8%)
Query: 37 EIREREREIETRKEGKKER---ESERKKERREREKRKRERE------KERKRERGKKEKK 87
E E+E+ R+E +KE E E + +RRER ++ +E E +ER+R + ++ +
Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872
Query: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKE--KKERGRTSKEGKERERKEERKREERK 145
R + E ERK+RR K +++ RK+++ ++E +E +E+ R++E++R+ R+
Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE 932
Query: 146 ERERKKEERE---KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
E + ++EE + +ERE++ R++RER+ +K+ ++KE++ + +R R+ER+K+
Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992
Query: 203 KERRERKKERKKKEERKKERQKDRQTNWREKERGKRE-----RKERKK 245
+E ++++E+ +EER+K R+++ + +R+K+ ++E R+ER+K
Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREK 1040
Score = 112 bits (279), Expect = 4e-25
Identities = 70/234 (29%), Positives = 141/234 (60%), Gaps = 29/234 (12%)
Query: 37 EIREREREIETRKEGKKERESERKKE---RREREKRK-REREKERKRERGKKEKKGERKK 92
E RE+ R E ++ +K+ E ++++E R EREKR+ +ERE++ + E ++++ +
Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG 1065
Query: 93 EERERKKR-------RREKENKEGEE---KEKRKKKEKKERGRTSKEGKE---------R 133
EERE ++R R+E+E ++ EE +E+ +K+ ++ER R +E +E R
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125
Query: 134 ERKEERKREERKERERKKEEREKERE---RKERKKRERKQVGEKEEERKEKERKERKKRE 190
E +E+R+R+E + + R++EE ++E E R+E +KR R+++ + E +E +++E +
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Query: 191 RNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWR---EKERGKRERK 241
+++R++ERER+ R E + +R+K+++R ++ + W+ EKE R+ K
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239
Score = 111 bits (278), Expect = 5e-25
Identities = 61/228 (26%), Positives = 136/228 (59%), Gaps = 19/228 (8%)
Query: 34 WQSEIREREREIETRKEGKKERESE----------------RKKERREREKRKREREKER 77
WQ RE R E + + K E+E R+K R E+++++RER+
Sbjct: 180 WQE--REERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV 237
Query: 78 KRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE 137
+E +KE + +E +K + E+ ++ E +E+ ++ K ER +E +E E+++
Sbjct: 238 FQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ 297
Query: 138 ERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERK 197
+R R E++ R +++EER +++E + ++ R+Q E+ E++ +E++ER++++ R++ +
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Query: 198 KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+ RE++ RRE+++ER++++ R +E+Q R+ R +++ +RE++ R++
Sbjct: 358 ERREQQLRREQEEERREQQLR-REQQLRREQQLRREQQLRREQQLRRE 404
Score = 111 bits (278), Expect = 5e-25
Identities = 70/226 (30%), Positives = 138/226 (61%), Gaps = 19/226 (8%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKK--EKKGERKKEERE 96
R +E + + R+E + +E E + RR+ RK E+ R +E+G+K E++ +++ERE
Sbjct: 1330 RRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERE 1389
Query: 97 RKKRRREKE----NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK-K 151
RK + E++ +E + ++ R +K ++E + S++ ++R+ +EE ++ R+ERERK
Sbjct: 1390 RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFL 1449
Query: 152 EEREKERERKERKKRERKQV-GEKEEERKEKERKERKKRERNRKERKKERERK----ERR 206
EE ++ R+ + RK RE +Q+ E+EE++ ++ ++RK E ++ R++ER+RK E R
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509
Query: 207 ERKKERKKKEERKKERQKDRQTNW-------REKERGKRERKERKK 245
++ ERK EE ++ ++ RQ + R +ERG++ R++R +
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR 1555
Score = 110 bits (276), Expect = 9e-25
Identities = 72/234 (30%), Positives = 144/234 (61%), Gaps = 30/234 (12%)
Query: 40 EREREIETRKEGKKERESERKKE---RREREKRKREREKE-RKRERGKKEKKGERKKEER 95
E+ R E ++ ++E E ++++E R E+EKR++ERE++ R+ E +++K+ +R ++E
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218
Query: 96 ER---------KKRRREKENK---EGEEKEK-RKKKEKKERGRTSK--------EGKERE 134
+R +K ++NK +G E E+ R+ ++ + R R S+ E +ER+
Sbjct: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD 1278
Query: 135 RKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRK 194
R++ER+R ++++R +EE+ + E+KE K+R+RK EK+ R+E+E K R+++E +RK
Sbjct: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEK-RRRQETDRK 1337
Query: 195 ERKKERERKERRERKKERKKKEERKKERQKDRQTNWR----EKERGKRERKERK 244
R++E+ +ER E+ R++++ + +E + Q R E++R +R+ +ERK
Sbjct: 1338 FREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERK 1391
Score = 110 bits (275), Expect = 1e-24
Identities = 69/241 (28%), Positives = 149/241 (61%), Gaps = 31/241 (12%)
Query: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
G +S +++R +E + R+ ++R+ E + +R R+KR+ E+ER+ G+++ + + +
Sbjct: 105 GKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQ---EQERELAEGEEQSEKQERL 161
Query: 93 EERERKKRRRE--KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE-----RK 145
E+R+R++R E ++ +E +E+E+R+ +E++ + E +E +E+ +R E RK
Sbjct: 162 EQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRK 221
Query: 146 ERERKKEEREKERER-----KERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER 200
RE K+++R + ++R +E++ R+R+ V KEEE+ ++E +R++ + +E+ ++
Sbjct: 222 GREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL 281
Query: 201 ERKE-RRERKKE-------------RKKKEERKKERQKDR--QTNWREKERGKRERKERK 244
ER+E RRER++E R+K+EE ++E+Q++R Q RE++ +RE++ R+
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 245 K 245
+
Sbjct: 342 E 342
Score = 110 bits (274), Expect = 1e-24
Identities = 68/267 (25%), Positives = 150/267 (56%), Gaps = 54/267 (20%)
Query: 33 GWQSEIREREREIETRKEGKKERESERKKERRERE------KRKREREKERKRERGKKEK 86
G E R R E+ + +++ E +R+ E R+R+ +R+R++ +E++RE + E+
Sbjct: 94 GLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEE 153
Query: 87 KGERKKEERERKKRRREKE----NKEGEEKEKRKKKEK---------------------- 120
+ E+++ +R ++RR++E +E +E+E+R+ +E+
Sbjct: 154 QSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRR 213
Query: 121 -----KERGRTSKEGKERER----------KEERKREE--RKERERKKEE-----REKER 158
+ +GR K+ + RER KE RKRE RKE E+ +EE RE +
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 159 ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEER 218
E ++ +K ER+++ + +E ++++++ R++++ RK+ ++ RE++E R ++ER++++E
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333
Query: 219 KKERQKDRQTNWREKERGKRERKERKK 245
++E+Q R+ R +++ +RE++E ++
Sbjct: 334 RREQQLRREQEERREQQLRREQEEERR 360
Score = 110 bits (274), Expect = 1e-24
Identities = 73/242 (30%), Positives = 133/242 (54%), Gaps = 39/242 (16%)
Query: 34 WQSEIREREREIET-----------RKEGKKERESERKKERREREKRKREREKERKRERG 82
WQ E ER+R T RKE + +E E + +R EREKR+R+ ++ + RE
Sbjct: 876 WQLE-EERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE-- 932
Query: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK--------------ERGRTSK 128
E + ++ E + R E+E + +E+E++ +K+KK +R R +
Sbjct: 933 ------EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986
Query: 129 EGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEK--EEERKEKERKER 186
E K RE +E ++ EE+ RE +++ R +E ER+ RKK E +Q E+ EER+++ +ER
Sbjct: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Query: 187 KKRERNRKERKKERER---KERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
+++ R +E ++E E+ +ER R+++ +++ RK+E + + +E KR R+ER
Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Query: 244 KK 245
++
Sbjct: 1107 ER 1108
Score = 109 bits (273), Expect = 2e-24
Identities = 68/239 (28%), Positives = 135/239 (56%), Gaps = 40/239 (16%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKRE---REKERKRERGK------------ 83
++ RE ++E ++ER +R K E E+R++E E+E+ RER K
Sbjct: 651 QQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLES 710
Query: 84 -------------KEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEG 130
++++G+R+++E+E K+RRRE E + EE+ ++++++E+ R
Sbjct: 711 EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQ 770
Query: 131 KERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190
+ E K ER R+ R +E+RE++ +ER++RE++ + EEE KE+ R++R++RE
Sbjct: 771 WQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFL--PEEEEKEQRRRQRRERE 828
Query: 191 RNRKERKKERERKERRERKKERKKKEE---------RKKERQKDRQTNWREKERGKRER 240
+ + +E E+ +RRER ++ +++E+ R +E+++D++ W+ +E KR R
Sbjct: 829 K-ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRR 886
Score = 109 bits (272), Expect = 2e-24
Identities = 60/215 (27%), Positives = 139/215 (64%), Gaps = 11/215 (5%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
+ER+R+ ++ + +E ERK E++ R++E +++ ++ER +K ++ E+ +ERE +
Sbjct: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634
Query: 99 K-RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE-----ERKREERKERERKKE 152
+ R+E++ K EE+ + +++E++++ R ++ K RE ++ E ++ R+ER+RK
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFR 1694
Query: 153 EREKERERKERKKR---ERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERK 209
E E++ R+ER+++ E +Q+ +E ERK +E ++ ++ + R++ER RK E +
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ 1754
Query: 210 KERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
+++E++ + +++DR+ +RE+E+ ++ER+E++
Sbjct: 1755 LRPEREEQQLRRQERDRK--FREEEQLRQEREEQQ 1787
Score = 108 bits (269), Expect = 6e-24
Identities = 66/234 (28%), Positives = 152/234 (64%), Gaps = 24/234 (10%)
Query: 35 QSEIREREREIETRKEGKKERESERKKE-RREREKRKREREKE---RKRERGKKEKKGER 90
+ +R +ERE + KE ++ R ER+++ R++R+++ RE E++ ++R+R +E++ +
Sbjct: 1380 EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQV 1439
Query: 91 KKEERERK------KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER 144
+++ERERK + R+E+ K EE++ +++E+++ R ++ K E +++ +R+ER
Sbjct: 1440 RRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQER 1499
Query: 145 KERERKKEEREKERERK--------ERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196
+ R++E R +E ERK R++R+RK + E+++ R++ ER ++++++R+RK R
Sbjct: 1500 DRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ-ERGQQRRQDRDRKFR 1558
Query: 197 KKERERKERRE-----RKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
++E+ R+ER E ++++RK + E +K R+++++ + E E+ R ++ +++
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
Score = 107 bits (268), Expect = 7e-24
Identities = 66/231 (28%), Positives = 135/231 (58%), Gaps = 21/231 (9%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+SE +E R+ + R+E ++ER +R K E E+ ++ ++E + ER ++E E +++
Sbjct: 635 KSEEQEERRQQQLRRE-QQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA 693
Query: 95 RERKKRRREK-----ENKEGEEKEK---RKKKEKKERGRTSKEGKERERKEERKREERKE 146
RER K R K E++ + K R +K++ +R R +E K R R+ E + +E +
Sbjct: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEER 753
Query: 147 RERKKEEREKERE------RKERKKRERKQVGEKEEERKEKERKERKKRERNRKER---- 196
R+++E E+ R+ +E+ +R R+++ + R+++ER+ R + + R++R
Sbjct: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE 813
Query: 197 --KKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+KE+ R++RRER+KE + EE ++ ++++R +E+E G +E +ER++
Sbjct: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864
Score = 107 bits (267), Expect = 9e-24
Identities = 59/213 (27%), Positives = 136/213 (63%), Gaps = 13/213 (6%)
Query: 41 REREIETRKEGKKERESERKKERREREK---------RKREREKERKRERGKKEKKGERK 91
RE E+ +++G+K E E++ R+ERE+ R +ERE++ +++R +K ++ E++
Sbjct: 1363 REEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ 1422
Query: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
+ER ++ RE+E + ++ +RK E++++ R + K RE EE+ +ER+E++ +
Sbjct: 1423 LSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFRE--EEQLLQEREEQQLHR 1480
Query: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKE 211
+ER+++ +E++ R +++ + E+ + ERK E ++ +++R+RK +E ++
Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQE--EQ 1538
Query: 212 RKKKEERKKERQKDRQTNWREKERGKRERKERK 244
+ +++ER ++R++DR +RE+E+ ++ER+E++
Sbjct: 1539 QLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
Score = 107 bits (267), Expect = 9e-24
Identities = 64/225 (28%), Positives = 146/225 (64%), Gaps = 20/225 (8%)
Query: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERK-RERGKKEKKGERKKEER 95
+ RE E+ ++ R+E + R+ ER ++ E E++ R +E++RK RE+ + ++ ERK E
Sbjct: 1462 KFREEEQLLQEREEQQLHRQ-ERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE 1520
Query: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
E++ R++++ K +E+++ +++E+ ++ R ++ K RE EE+ R+ER+E++ ++ER+
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFRE--EEQLRQEREEQQLSRQERD 1578
Query: 156 KE---RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER---ERKERRERK 209
++ E+K R++ + ++ E E++ + +E +++ ++ER+RK R+ E+ ER+E++ +
Sbjct: 1579 RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHR 1638
Query: 210 KERKKK----------EERKKERQKDRQTNWREKERGKRERKERK 244
+ER +K +ER+++ + DR +RE+E+ +E +E++
Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ 1683
Score = 107 bits (266), Expect = 1e-23
Identities = 66/224 (29%), Positives = 134/224 (59%), Gaps = 17/224 (7%)
Query: 35 QSEIRER--EREIETRKEGKKERESERKKER--REREKRKREREKERKRERGKKEKKGER 90
+ E RE+ +RE E R++ +RE ER+++R RE+E+R +R K + ER ++E++ E+
Sbjct: 559 EQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQ 618
Query: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEER-----KREERK 145
+ + E ++ RR++ K E++E+R+++ ++E+ ++ +RE +EER KRE +
Sbjct: 619 RLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEE 678
Query: 146 ER-ERKKEEREKERERKERKKRERKQVGEKEEERKEKE-------RKERKKRERNRKERK 197
ER E++ E E+E+ R+ K R K + E E ++ RK+ +R R +E K
Sbjct: 679 ERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEK 738
Query: 198 KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERK 241
+ R E + +++ER ++++++E+++D W+ +E+ +R R+
Sbjct: 739 RRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782
Score = 107 bits (266), Expect = 1e-23
Identities = 63/226 (27%), Positives = 147/226 (65%), Gaps = 18/226 (7%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKER--KRERGKK--EKKGER 90
+ ++R +ERE + +E ++ R+ ER ++ RE E+ +ERE+++ ++ER +K E++ +
Sbjct: 1436 EQQVRRQERERKFLEEEQQLRQ-ERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQL 1494
Query: 91 KKEERERKKRRREKENKEGEEK--EKRKKKEKKERGRTSKEGKERERKEERKREERKERE 148
+++ER+RK R +E ++E E K E+ ++ +++R R + +++ R++ER ++ R++R+
Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD 1554
Query: 149 RKKEEREKERERKE-----RKKRERK------QVGEKEEERKEKERKERKKRERNRKERK 197
RK E E+ R+ +E R++R+RK +V +E+ERK E +++ +R+ +++ +
Sbjct: 1555 RKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLR 1614
Query: 198 KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
+ER+RK R + + ++++E++ +++DR+ E + ++ER+++
Sbjct: 1615 QERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQ 1660
Score = 107 bits (266), Expect = 1e-23
Identities = 64/231 (27%), Positives = 140/231 (60%), Gaps = 19/231 (8%)
Query: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREK---------RKREREKERKRER 81
Q G Q +ER+R+ ++ +ERE E++ R+ER++ R++ERE++ + +R
Sbjct: 1607 QEGQQQLRQERDRKFREDEQLLQERE-EQQLHRQERDRKFLEEEPQLRRQEREQQLRHDR 1665
Query: 82 GKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK- 140
+K ++ E+ +E E ++ RR++ +++ E+E++ +++++ER +E + R ++ ERK
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF 1725
Query: 141 REERKERERKKEE--REKERERK------ERKKRERKQVGEKEEERKEKERKERKKRERN 192
REE + R+ ++E R +ER RK R +RE +Q+ +E +RK +E ++ ++
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE 1785
Query: 193 RKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
++ R +E +RK R E + ++++E++ + +Q+D + W E++ E+++R
Sbjct: 1786 QQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836
Score = 106 bits (265), Expect = 2e-23
Identities = 69/227 (30%), Positives = 139/227 (61%), Gaps = 20/227 (8%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
WQ E E+E + K K RE+E+ ++ + + R R+ +++ + G+++ ER +E
Sbjct: 1225 WQWE-PEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQ---ERDRE 1280
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKE--RERKEERKREERKERERKK 151
+ R+ ++R++ E E+ E+ ++KE K R R S+E K+ RE +EE++R + +R+ ++
Sbjct: 1281 QERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
Query: 152 EER---EKERERKERKKRERK----QVGEKEEERKEKERKERKKR-ERNRKERKKE---- 199
EE+ E+E + R++R+RK ++ +E+ RK E ++R +R ER RK K+E
Sbjct: 1341 EEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR 1400
Query: 200 -RERKERRERKKERKKKEERKKERQKDRQTNWREKERG-KRERKERK 244
+ER+++ + ++RK +EE ++ +++R +RE+E+ +R+ +ERK
Sbjct: 1401 CQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERK 1447
Score = 105 bits (263), Expect = 3e-23
Identities = 57/222 (25%), Positives = 148/222 (66%), Gaps = 16/222 (7%)
Query: 35 QSEIREREREIETRKEGKKERESERK--KERREREKRKREREKERKRERGKKEKKGERKK 92
+ ++R +ER+ + R++ + +E ERK +E ++ +++R+R+ ++ ++ +++++G++++
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRR 1550
Query: 93 EERERKKRRREKENKEGEEKE-KRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
++R+RK R E+ +E EE++ R+++++K R +E K R +++ERK E +++ R++
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQERDRKFR---LEEQKVRRQEQERKFMEDEQQLRRQ 1607
Query: 152 EEREKERERKERKKRERKQV-GEKEEERKEKERKERK--------KRERNRKERKKERER 202
E +++ R+ ++RK RE +Q+ E+EE++ ++ ++RK +R+ ++ + +R+R
Sbjct: 1608 EGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDR 1667
Query: 203 KERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
K R E + ++ +E++ + +++DR+ E+++ +R+ +ERK
Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKFR-EEEQQLRRQERERK 1708
Score = 105 bits (263), Expect = 3e-23
Identities = 57/220 (25%), Positives = 147/220 (66%), Gaps = 8/220 (3%)
Query: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90
Q G + ++R +ER+ + R+E ++ R ER+++ + E++ R +E ERK R +++ + E
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF-REEEQLRQET 1735
Query: 91 KKEERERKKRRR---EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147
++E+ R++R R E+E E +E++ ++++++R +E +ER+E++ R + +R
Sbjct: 1736 EQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDR 1795
Query: 148 ERKKEEREKERERKERKKRERKQVGE---KEEERKEKERKERKKRERNRKERKKERERKE 204
+ ++EE+ ++ ER+E++ R +++ G+ +EE+ + +E+++R ++ER+R+ R +E+ +
Sbjct: 1796 KFREEEQLRQ-EREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQ 1854
Query: 205 RRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
+ R++E++ +E +++R+++R+ RE+ +++++E++
Sbjct: 1855 EKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQR 1894
Score = 105 bits (262), Expect = 4e-23
Identities = 61/227 (26%), Positives = 137/227 (60%), Gaps = 23/227 (10%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKE-RKRERGKKEKKGERKKEERER 97
+ERE+++ ++ K E + +E E++ R++ER+++ R+ E+ + ++ ERK + E+
Sbjct: 1655 QEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ 1714
Query: 98 KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKE 157
+ RR+E E K EE++ R++ E+++ R + K E EE+ R ER+E++ +++ER+++
Sbjct: 1715 QLRRQELERKFREEEQLRQETEQEQLRRQERYRKILE--EEQLRPEREEQQLRRQERDRK 1772
Query: 158 --RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215
E + R++RE +Q+ +E +RK +E ++ ++ ++ R ++R+ K R E ++ + ++
Sbjct: 1773 FREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEE 1832
Query: 216 EERKKERQKDRQTN------------------WREKERGKRERKERK 244
+E++ +++DRQ W+E+E+ +R+ +ERK
Sbjct: 1833 QEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERK 1879
Score = 105 bits (261), Expect = 5e-23
Identities = 74/251 (29%), Positives = 142/251 (56%), Gaps = 47/251 (18%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
R +ERE + R+E + ++E E+ R EREKR+R+ + + RE + +++ E+ E K
Sbjct: 1102 RRQERERQCREEEELQQEEEQLL-REEREKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160
Query: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERK----EERKREERKERERKKEER 154
+RR+E E + EE+E ++++E+ R K +ERER+ EE +R++RK+R R +++R
Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQR 1220
Query: 155 -------EKERERKER------KKRERKQ---------------------VGEKEEERKE 180
E E+E R K RE +Q +GE++E +E
Sbjct: 1221 SDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDRE 1280
Query: 181 KERKERKKRERN-------RKERKKERERKERRERKKERKKKEER-KKERQKDRQTNWRE 232
+ER+ ++R+R+ +E +KE +R++R+ +++++ +EER +K R+++ +RE
Sbjct: 1281 QERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
Query: 233 KERGKRERKER 243
+E+ +ER+E+
Sbjct: 1341 EEQLLQEREEQ 1351
Score = 105 bits (261), Expect = 5e-23
Identities = 67/223 (30%), Positives = 149/223 (66%), Gaps = 18/223 (8%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKER--KRERGKK--EKKGER 90
+ + E E+++ R+EG+++ ER ++ RE E+ +ERE+++ ++ER +K E++ +
Sbjct: 1594 ERKFMEDEQQLR-RQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQL 1652
Query: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
+++ERE++ R +++ K EE++ ++ E+++ R ++ K RE +++ +R+ER ER+
Sbjct: 1653 RRQEREQQLRH-DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER-ERKFL 1710
Query: 151 KEEREKERERKERKKRERKQVGEKEEE----RKEKERK----ERKKRERNRKE-RKKERE 201
+EE++ R+ ERK RE +Q+ ++ E+ R+E+ RK E+ + ER ++ R++ER+
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Query: 202 RKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
RK R E + ++++E++ + ++ DR+ +RE+E+ ++ER+E++
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRK--FREEEQLRQEREEQQ 1811
Score = 104 bits (259), Expect = 8e-23
Identities = 67/228 (29%), Positives = 140/228 (61%), Gaps = 21/228 (9%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKE---KKGERK 91
+ ++ ++R+ + +E ++ R ER ++RR+ RK E++ ++ER +++ ++ +RK
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1580
Query: 92 KEERERKKRRREKENKEGEEKEKRKKKE-----KKERGRTSKEGKERERKEERKREERKE 146
E+K RR+E+E K E++++ +++E ++ER R +E ++ ++ E ++ R+E
Sbjct: 1581 FRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE 1640
Query: 147 RERK---------KEEREKE-RERKERKKRERKQV-GEKEEERKEKERKERKKRERNRKE 195
R+RK ++ERE++ R ++RK RE +Q+ E EE++ ++ ++RK RE ++
Sbjct: 1641 RDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700
Query: 196 RKKERERKERRERKKERKKKEERK--KERQKDRQTNWREKERGKRERK 241
R++ERERK +E ++ R+++ ERK +E Q ++T + R +R RK
Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRK 1748
Score = 103 bits (256), Expect = 2e-22
Identities = 68/225 (30%), Positives = 134/225 (59%), Gaps = 22/225 (9%)
Query: 37 EIREREREIETRKEGKKERESERKKE---RREREKRKR-EREKERKRERGKKEKKGERKK 92
E RE R E ++ +KE E ++++E R E EKR+R ERE++ + E ++++ + +
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125
Query: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
EERE K+RR+E E + EE+E ++++E+ R E E+ R++E +R+ R+E E ++E
Sbjct: 1126 EERE-KRRRQELERQYREEEEVQQEEEQLLR-----EEPEKRRRQELERQYREEEELQQE 1179
Query: 153 EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERK----KERERKER--- 205
E + RE +E++++ER++ +EEE + ++RK+R + E R + K E+E R
Sbjct: 1180 EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239
Query: 206 -----RERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
RE ++ R+ ++ + ++RQ + E+ +R+R++ ++
Sbjct: 1240 VYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERR 1284
Score = 101 bits (252), Expect = 5e-22
Identities = 68/239 (28%), Positives = 135/239 (56%), Gaps = 33/239 (13%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE-RER 97
RE+E +E R + ++E E ++ERRE+ ++ E E+ER+++ K E++ ER++++ R
Sbjct: 592 REQEERLEQRLK-REEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE 650
Query: 98 KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK------- 150
++ RRE+ K EE+E+ +++ K+E +E + E ++E+ RE K R K
Sbjct: 651 QQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLES 710
Query: 151 --------------KEEREKERERKERKKRERK-QVGEKEEERKEKERKERKKRE----R 191
K+E ++ R+ +E K+R R+ ++ +EEER ++++E ++R +
Sbjct: 711 EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQ 770
Query: 192 NRKERKKERERKERRER-----KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+ E K ER R+ R ++ER+ + E +++R++ EKE+ +R+R+ER+K
Sbjct: 771 WQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREK 829
Score = 101 bits (251), Expect = 7e-22
Identities = 68/257 (26%), Positives = 143/257 (55%), Gaps = 24/257 (9%)
Query: 12 KLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKE---RESERKKERREREK 68
K +L+ + + SK ++P Q R R+ + E R+ + E +E ER +++ E+
Sbjct: 703 KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE 762
Query: 69 RKRER----EKERKRERGKKEKKGERK-KEERERKKRRREKENKEGEEKEKRKKKEKKER 123
++R+ + E K ERG++ +E+RER+ R E++ +E + ++KE++ R
Sbjct: 763 QRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR 822
Query: 124 GRTSKEGKERERKEERKREERKERERKKEERE------KERERKERKKRERKQVGEKEEE 177
R +E KE + EE ++ +R+ER ++ +E E +ER R + ++R++K + EEE
Sbjct: 823 QRRERE-KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEE 881
Query: 178 RKEKER--------KERKKRERNRKERKKERERKERRE-RKKERKKKEERKKERQKDRQT 228
RK + +E+ ++E+ + ++E ++E RE R+++ ++++ R++E+ + +
Sbjct: 882 RKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEE 941
Query: 229 NWREKERGKRERKERKK 245
+ER KR R+ER++
Sbjct: 942 QLLREEREKRRRQERER 958
Score = 101 bits (251), Expect = 7e-22
Identities = 55/214 (25%), Positives = 136/214 (63%), Gaps = 6/214 (2%)
Query: 35 QSEIREREREIETRKEGKKERESERKKE-RREREKRKREREK--ERKRERGKKEKKGERK 91
+ ++ +ER+ + +E + R ER+++ R +R+++ RE E+ + E+ + ++ +RK
Sbjct: 1633 EQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRK 1692
Query: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
E E++ RR+E+E K +E+++ +++E + + R ++ ++ +E+ +R+ER + ++
Sbjct: 1693 FREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEE 1752
Query: 152 EEREKERERKERKKRER-KQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210
E+ ERE ++ +++ER ++ E+E+ R+E+E ++ + +E +RK R++E+ R+ER E++
Sbjct: 1753 EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQL 1812
Query: 211 ERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
++++ K R ++ Q E+E+ R+ ++R+
Sbjct: 1813 RPQQRD--GKYRWEEEQLQLEEQEQRLRQERDRQ 1844
Score = 100 bits (248), Expect = 2e-21
Identities = 64/253 (25%), Positives = 145/253 (57%), Gaps = 42/253 (16%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER-KKE 93
+S I + + ++E+ + ++ + R +++ + +R+ + EK R+RE + ++ ER ++
Sbjct: 698 KSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQ 757
Query: 94 ERERKKRRREKENKEGEEKEKRKK---------KEKKERGRTSKEGKERERKEERKREER 144
++E ++RR + EEK +R + +E++ER ++E ++RE++ + EE+
Sbjct: 758 QQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEK 817
Query: 145 KERERKKEEREKE----RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER---K 197
++R R++ EREKE E ++ ++RER Q ++EE+ +++++ R+ +E+ R ++ +
Sbjct: 818 EQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQ 877
Query: 198 KERERKERR--------------------ERKKERKKKEERKKERQKDRQTNWREKERGK 237
E ERK RR + ++E ++EER+K R+++++ +RE+E+ +
Sbjct: 878 LEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ 937
Query: 238 RE-----RKERKK 245
+E R+ER+K
Sbjct: 938 QEEEQLLREEREK 950
Score = 99.0 bits (245), Expect = 3e-21
Identities = 60/207 (28%), Positives = 124/207 (59%), Gaps = 9/207 (4%)
Query: 38 IREREREIETRKEGKKERES----ERKKERREREKRKREREKERKRERGK--KEKKGERK 91
++ERER+ +E ++E E ER+ RR+ +R+ +E+E ++E + +E+ +R+
Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102
Query: 92 KEERERKKRRREKENKEGEE--KEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
++ERER+ R E+ +E E+ +E+R+K+ ++E R +E +E +++EE+ E E+ R
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
Query: 150 KKEEREKERERKERKKRERKQVGEKEEER-KEKERKERKKRERNRKERKKERERKERRER 208
++E + RE +E ++ E + + E++E+R +E+ER+ R++ E R++RK+ +++R
Sbjct: 1163 RQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD 1222
Query: 209 KKERKKKEERKKERQKDRQTNWREKER 235
K + + E+ R RE E+
Sbjct: 1223 LKWQWEPEKENAVRDNKVYCKGRENEQ 1249
Score = 99.0 bits (245), Expect = 3e-21
Identities = 54/202 (26%), Positives = 124/202 (61%), Gaps = 15/202 (7%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRK----------REREKERKRERGKK 84
+ ++R +E E + R+E + +E+E+++ RR+ RK RE ++ R++ER +K
Sbjct: 1713 EQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Query: 85 EKKGERKKEERERKK-RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143
++ E+ ++ERE ++ R +E + K EE++ R+++E+++ ++GK R +E+ + EE
Sbjct: 1773 FREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEE 1832
Query: 144 RKERERKKEEREKERER----KERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE 199
+++R R++ +R+ E +E+ +RE +++ ++EE+++ +ER+ + + E R+++K+E
Sbjct: 1833 QEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEE 1892
Query: 200 RERKERRERKKERKKKEERKKE 221
+ ++ E K + K R E
Sbjct: 1893 QRHRQVGEIKSQEGKGHGRLLE 1914
Score = 98.6 bits (244), Expect = 4e-21
Identities = 64/223 (28%), Positives = 139/223 (62%), Gaps = 25/223 (11%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKE--RKRERGKKEKKGERKK 92
+ ++R +ERE + +E ++ R E +++ RE E+ ++E E+E R++ER +K + E+ +
Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR 1756
Query: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
ERE ++ RR++ +++ E+E+ ++ E++E+ S+E + R+EE+ R+ER+E++
Sbjct: 1757 PEREEQQLRRQERDRKFREEEQLRQ-EREEQQLRSQESDRKFREEEQLRQEREEQQL--- 1812
Query: 153 EREKERERKERKKRERKQVGEKEEERKEKERKERKKRER-----------NRKERKKERE 201
R ++R+ K R + E+ Q+ EE++++ R+ER ++ R R+E++ +E
Sbjct: 1813 -RPQQRDGKYRWEEEQLQL----EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQE 1867
Query: 202 RKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
+++R +++ERK +EE + +QK+ Q R ++ G+ + +E K
Sbjct: 1868 EEQKRRQERERKLREEHIRRQQKEEQ---RHRQVGEIKSQEGK 1907
Score = 70.5 bits (171), Expect = 1e-12
Identities = 45/172 (26%), Positives = 99/172 (57%), Gaps = 18/172 (10%)
Query: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK-- 145
G+ + E++ R KE+ + +++ ++ + R R +E + R+++R+ +ER+
Sbjct: 90 GQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELA 149
Query: 146 --ERERKKEEREKERERKERKK---RERKQVGEKEEERKEKERKERKKRERNRKERKKER 200
E + +K+ER ++R+R+ R + R+R++ E+EE R E+E+ + K + E +
Sbjct: 150 EGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCK--GHETEEFPDE 207
Query: 201 ERKERRE----RKKERKKKEERKKER-----QKDRQTNWREKERGKRERKER 243
E+ RRE R+K R++K+++++ER Q++ + WR++E R+ +E+
Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
Score = 47.0 bits (110), Expect = 2e-05
Identities = 29/108 (26%), Positives = 62/108 (57%), Gaps = 12/108 (11%)
Query: 35 QSEIREREREIETRKEGKK---ERESERKKERREREKRKRER----EKERKRERGKKEKK 87
+ ++R ++R+ + R E ++ E + +R ++ R+R+ R E+ EK R+ E+ +++
Sbjct: 1809 EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEE 1868
Query: 88 GERKKEERERKKR-----RREKENKEGEEKEKRKKKEKKERGRTSKEG 130
+++++ERERK R R++KE + + + K +E K GR + G
Sbjct: 1869 EQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPG 1916
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 127 bits (319), Expect = 9e-30
Identities = 65/190 (34%), Positives = 125/190 (65%), Gaps = 5/190 (2%)
Query: 38 IREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERER 97
IRERER+ E ++ K+ +E R+K+R + R R+R+++R+R+R + +RK+E
Sbjct: 57 IRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDR---DRKRERWGD 113
Query: 98 KKRRREKENKEGEEKEKRKKKEK-KERGRTSKEGKERERKEERKREERKERERKKEEREK 156
+ R E E +E E+++ +K+EK +ER R + G +++R+ E +++ +ERE + ER +
Sbjct: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
Query: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216
+RER+ +K+RE ++ ++E +R EKE +ER + + +E+ + RER+ R+R KER ++
Sbjct: 174 DRERERQKQRETRRDRDRERQR-EKEDRERDRDRQKEREKDRYRERETGRDRDKERDRER 232
Query: 217 ERKKERQKDR 226
+R+K+R + +
Sbjct: 233 QREKDRDRQK 242
Score = 119 bits (299), Expect = 2e-27
Identities = 62/184 (33%), Positives = 128/184 (69%), Gaps = 5/184 (2%)
Query: 64 REREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKER 123
RERE R+RERE++RKR + + +K +++R+R+++R + + + KR++ ++R
Sbjct: 58 RERE-RQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
Query: 124 GRTSKEGKERERKEERKREERKERERKKE-EREKERERKERKKRERKQVGEKEEERKEKE 182
++ +ERER+ +RKRE+ +ER+R++E +K+RE + K R+R++ + E +++E
Sbjct: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
Query: 183 RKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNW-REKERGKRERK 241
R+ +K+RE R++R +ER+R E+ +R+++R +++ER+K+R ++R+T R+KER + ++
Sbjct: 177 RERQKQRE-TRRDRDRERQR-EKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQR 234
Query: 242 ERKK 245
E+ +
Sbjct: 235 EKDR 238
Score = 116 bits (291), Expect = 2e-26
Identities = 65/191 (34%), Positives = 121/191 (63%), Gaps = 6/191 (3%)
Query: 55 RESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEK 114
RE ER++ER + KR +ER +E+ RE K + ++ ER+R + R K + G+ +
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
Query: 115 RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEK 174
+ + ++ER R +E++R+ +R+RE +++R + E EK+R+R ER+ E ++ ++
Sbjct: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDR-EIETEKDRDR-EREMGETERYRDR 175
Query: 175 EEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234
E ER +K+R+ R+ R+R R+ K++RER R+R+KER+K R++E +DR R++E
Sbjct: 176 ERER-QKQRETRRDRDRERQREKEDRERD--RDRQKEREKDRYRERETGRDRDKE-RDRE 231
Query: 235 RGKRERKERKK 245
R + + ++R+K
Sbjct: 232 RQREKDRDRQK 242
Score = 89.7 bits (221), Expect = 2e-18
Identities = 55/165 (33%), Positives = 99/165 (60%), Gaps = 24/165 (14%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ R+RER + +E + ER+ ER+++R RKRE+++ER+R+R E ++ +E
Sbjct: 101 WRDRDRKRERWGDRDRETETERQEERERQR----DRKREKDRERQRQR---EIGIDKDRE 153
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
K R RE+E E E R+ +ER+++ E +R+ +ER+R+KE+
Sbjct: 154 IETEKDRDREREMGETERYRDRE--------------RERQKQRETRRDRDRERQREKED 199
Query: 154 REKERERKERKKRERKQVGEKEEER-KEKERKERKKRERNRKERK 197
RE++R+R +K+RE+ + E+E R ++KER ++RE++R +K
Sbjct: 200 RERDRDR--QKEREKDRYRERETGRDRDKERDRERQREKDRDRQK 242
Score = 60.1 bits (144), Expect = 2e-09
Identities = 25/76 (32%), Positives = 55/76 (72%), Gaps = 1/76 (1%)
Query: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
G R+RERE + ++E +++R+ ER++E+ +RE R R+R+KER+++R ++ + G +
Sbjct: 167 GETERYRDRERERQKQRETRRDRDRERQREKEDRE-RDRDRQKEREKDRYRERETGRDRD 225
Query: 93 EERERKKRRREKENKE 108
+ER+R+++R + +++
Sbjct: 226 KERDRERQREKDRDRQ 241
Score = 52.4 bits (124), Expect = 4e-07
Identities = 29/86 (33%), Positives = 55/86 (63%), Gaps = 6/86 (6%)
Query: 163 RKKRERKQVGEKEEERKEKERKERKKRERNR-KERKKERERKERRERKKERK--KKEERK 219
R R + + E ++E+ER+ ++ +ER+R K+R+ E++R +R+R +ER+ + +RK
Sbjct: 48 RGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRK 107
Query: 220 KERQKDRQTNWREKERGKRERKERKK 245
+ER DR RE E ++E +ER++
Sbjct: 108 RERWGDRD---RETETERQEERERQR 130
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 125 bits (313), Expect = 4e-29
Identities = 71/231 (30%), Positives = 129/231 (55%), Gaps = 30/231 (12%)
Query: 41 REREIETRKEGKKERESERKKERREREK--RKREREKERKRERGKKEKKGERKKEERERK 98
R+R + R R+K+RR + +KR + +ER++ R + + +RK + K
Sbjct: 326 RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK 385
Query: 99 KRRREKENKEGEEKEKRKKKEK-KERGRTSKEGKERERKEERKREERKERERKKE---ER 154
++ R KE +E+E+ K++EK KERG+ KERE+ E+ +E+ +ERER+KE +R
Sbjct: 386 EKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDR 445
Query: 155 EKERERKERKKRERKQVGEKE-EERKEKERKER---KKRERNRKERKKERERKERRERKK 210
+KE+E+++ K++ER++ KE +E+++K++K R + +R+ R RER+ RR R
Sbjct: 446 DKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSS 505
Query: 211 ER--------------------KKKEERKKERQKDRQTNWREKERGKRERK 241
R + K+++K+E+++D + RE+ER RK
Sbjct: 506 SRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRK 556
Score = 123 bits (309), Expect = 1e-28
Identities = 72/214 (33%), Positives = 128/214 (59%), Gaps = 15/214 (7%)
Query: 39 REREREIETRKEGKKE-RESERKKERREREKRKREREKERKRERGK-----KEKKGERKK 92
R R + RK+ +++ +E ER KE+ ++R+RE+E+E+++ERGK KE++ +R+K
Sbjct: 368 RSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREK 427
Query: 93 EERERKKRRREKENKEGEEKEKRKKKEK-KERGRT-SKEGKERERKEERKREERKERERK 150
++ + ++R REKE+++ +KEK K+++K KER + SKE E+ +K+++ R +
Sbjct: 428 DKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 487
Query: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER---KERRE 207
+ R RER+ R+ R + + K K + R RN+K++K+E+ER ERRE
Sbjct: 488 RRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRE 547
Query: 208 RKKE---RKKKEERK-KERQKDRQTNWREKERGK 237
R++ RK +R KE+ + T+ +EKE K
Sbjct: 548 RERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNK 581
Score = 119 bits (299), Expect = 2e-27
Identities = 67/208 (32%), Positives = 114/208 (54%), Gaps = 7/208 (3%)
Query: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
E+ +R RE ++ E ES + ER+ R R K R + +K + K
Sbjct: 277 EVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSR 336
Query: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE-ERE 155
R R ++ K KK+ K R S+ K + RE+ KE+ER KE +RE
Sbjct: 337 SHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDRE 396
Query: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215
KERER++ +++E K+ G+ ++ KE+E+ K +E K+R++ERE++ ++R KE++K+
Sbjct: 397 KEREREKEREKE-KERGKNKDRDKEREKDREKDKE---KDREREREKEHEKDRDKEKEKE 452
Query: 216 EERKKERQKDRQTNWREKERGKRERKER 243
++++KER+KDR EK K+++K R
Sbjct: 453 QDKEKEREKDRSKEIDEKR--KKDKKSR 478
Score = 117 bits (293), Expect = 9e-27
Identities = 60/213 (28%), Positives = 117/213 (54%), Gaps = 5/213 (2%)
Query: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90
+ G +E + TR + + +S +++R + + R R + R R++ ++ K
Sbjct: 296 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 355
Query: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
KK + R+ RR+ + +K K +++ KE+ R ++ +E+ER+ E++RE+ KER +
Sbjct: 356 KKRSKSRE-RRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 414
Query: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210
K +R+KERE+ K +E+ + E+E+E ++ KE++K + KER+K+R ++ +RKK
Sbjct: 415 K-DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 473
Query: 211 ERKKKEERKKERQKDRQTNWREKERGKRERKER 243
++K R R + R R +R R+ R
Sbjct: 474 DKK---SRTPPRSYNASRRSRSSSRERRRRRSR 503
Score = 115 bits (287), Expect = 5e-26
Identities = 55/207 (26%), Positives = 120/207 (57%), Gaps = 5/207 (2%)
Query: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKK 99
E E ++G + R R K R + R R++ + + R + + ++++R R K
Sbjct: 294 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQSKHRSRSHNRSRSRQKDRRRSK 352
Query: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEG-KERERKEERKREERKERERKKEEREKER 158
+K +K E ++ R + +++ + ++E KE+ER +E+ RE+ +ERE+ EREKE+
Sbjct: 353 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK---EREKEK 409
Query: 159 ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEER 218
ER + K R++++ ++E+++++ +ER+K ++++KE+E+ + +ER+K+R K+ +
Sbjct: 410 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 469
Query: 219 KKERQKDRQTNWREKERGKRERKERKK 245
K+++ K +T R +R R ++
Sbjct: 470 KRKKDKKSRTPPRSYNASRRSRSSSRE 496
Score = 114 bits (285), Expect = 8e-26
Identities = 67/223 (30%), Positives = 122/223 (54%), Gaps = 15/223 (6%)
Query: 35 QSEIREREREIETRKEGKKERESERKKER---------REREK-RKREREKERKRERGKK 84
+ +I+E+ER E +E ++ERE ER+KE+ +EREK R++++EK+R+RER K+
Sbjct: 381 REKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKE 440
Query: 85 EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER 144
+K K++E+E+ K + ++++ E EKRKK +K S R R R+R R
Sbjct: 441 HEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 500
Query: 145 KERERKKEEREKERERKERKKRERKQVGEKEEERKEKER---KERKKRERNRKERK--KE 199
+ R + R + +++ + + K+++++EKER ER++RER+ RK +
Sbjct: 501 RSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 560
Query: 200 RERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
R+ KE+ E+ K++E KE +K+ + E +
Sbjct: 561 RDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 603
Score = 102 bits (253), Expect = 4e-22
Identities = 65/191 (34%), Positives = 103/191 (53%), Gaps = 18/191 (9%)
Query: 61 KERREREKRKREREK----ERKRERGKK-EKKGERKKEERERKKRRREKENKEGEEKEKR 115
KE E KR RE + + E GK E+KG R + K R K + +R
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHS------RR 326
Query: 116 KKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKE 175
K+ + K R R+ + R++ R + K+R + +E R+ R KR+ + KE
Sbjct: 327 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 386
Query: 176 EER-KEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234
+ER KEK+R++ ++RE KER+KE+ER + ++R KER+K E+ KE+ ++R+ REKE
Sbjct: 387 KERVKEKDREKERERE---KEREKEKERGKNKDRDKEREKDREKDKEKDRERE---REKE 440
Query: 235 RGKRERKERKK 245
K KE++K
Sbjct: 441 HEKDRDKEKEK 451
Score = 92.0 bits (227), Expect = 4e-19
Identities = 61/198 (30%), Positives = 109/198 (55%), Gaps = 8/198 (4%)
Query: 39 REREREIETRKEGKKERESERKKER-REREKRK-REREKERKRERGK-KEKKGERKKEER 95
R++ERE + K+ +K+RE ER+KE ++R+K K +E++KE++RE+ + KE +RKK+++
Sbjct: 417 RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK 476
Query: 96 ERKKRRREKENKEGEEKEK-RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
R R ++ + R+++ + R+ + K +RK R R R +K ++R
Sbjct: 477 SRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPR-SRNKKDKKR 535
Query: 155 EKERER-KERKKRERK-QVGEKEEERKEKERKERKKRERNRKERKKERERKERRE-RKKE 211
EKER+ ER++RER + + +R KE+ E+ KE KE + +E K+
Sbjct: 536 EKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKD 595
Query: 212 RKKKEERKKERQKDRQTN 229
+ EE K + + Q N
Sbjct: 596 APRTEENKIQHNGNCQLN 613
Score = 74.7 bits (182), Expect = 7e-14
Identities = 53/200 (26%), Positives = 90/200 (45%), Gaps = 33/200 (16%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK------ 92
RE+++E + +E +KE E +R KE+ + + +++EREK+R +E +K KK ++ +
Sbjct: 425 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 484
Query: 93 --------EERERKKRRREKENKEGE----------------EKEKRKKKEKKERGRTSK 128
RER++RR ++ + K+ KK +KER S
Sbjct: 485 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHIS- 543
Query: 129 EGKERERKEE-RKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERK 187
E +ERER RK ++ + K E+ + KE K V KE + K+ R E
Sbjct: 544 ERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSV-SKEVDDKDAPRTEEN 602
Query: 188 KRERNRKERKKERERKERRE 207
K + N + E + E
Sbjct: 603 KIQHNGNCQLNEENLSTKTE 622
Score = 45.4 bits (106), Expect = 4e-05
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 8/135 (5%)
Query: 12 KLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKR 71
K T + + S S+ ++ + R R T K K++ R ++ +KR
Sbjct: 476 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 535
Query: 72 EREKERKRERGKKEKKGERKKEERERK-KRRREKENKEGEEKEKRKKKEKKERGRTSKEG 130
E+E++ ER ++E+ +K +R K + EK + +EKE K+ + S
Sbjct: 536 EKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPD-------SSVS 588
Query: 131 KERERKEERKREERK 145
KE + K+ + EE K
Sbjct: 589 KEVDDKDAPRTEENK 603
Score = 43.1 bits (100), Expect = 2e-04
Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 5/105 (4%)
Query: 145 KERERKKEEREKERERKERKKRERKQ---VGEKEEERKEKERKERKKRERNRKERKKERE 201
K E + KE E ++ RE + + E K ERK + R R + + +
Sbjct: 262 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSK 321
Query: 202 RKERRERK--KERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
RR+R K R + R + RQKDR+ + ++ + R+ RK
Sbjct: 322 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRK 366
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 125 bits (313), Expect = 4e-29
Identities = 71/231 (30%), Positives = 129/231 (55%), Gaps = 30/231 (12%)
Query: 41 REREIETRKEGKKERESERKKERREREK--RKREREKERKRERGKKEKKGERKKEERERK 98
R+R + R R+K+RR + +KR + +ER++ R + + +RK + K
Sbjct: 210 RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK 269
Query: 99 KRRREKENKEGEEKEKRKKKEK-KERGRTSKEGKERERKEERKREERKERERKKE---ER 154
++ R KE +E+E+ K++EK KERG+ KERE+ E+ +E+ +ERER+KE +R
Sbjct: 270 EKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDR 329
Query: 155 EKERERKERKKRERKQVGEKE-EERKEKERKER---KKRERNRKERKKERERKERRERKK 210
+KE+E+++ K++ER++ KE +E+++K++K R + +R+ R RER+ RR R
Sbjct: 330 DKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSS 389
Query: 211 ER--------------------KKKEERKKERQKDRQTNWREKERGKRERK 241
R + K+++K+E+++D + RE+ER RK
Sbjct: 390 SRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRK 440
Score = 123 bits (309), Expect = 1e-28
Identities = 72/214 (33%), Positives = 128/214 (59%), Gaps = 15/214 (7%)
Query: 39 REREREIETRKEGKKE-RESERKKERREREKRKREREKERKRERGK-----KEKKGERKK 92
R R + RK+ +++ +E ER KE+ ++R+RE+E+E+++ERGK KE++ +R+K
Sbjct: 252 RSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREK 311
Query: 93 EERERKKRRREKENKEGEEKEKRKKKEK-KERGRT-SKEGKERERKEERKREERKERERK 150
++ + ++R REKE+++ +KEK K+++K KER + SKE E+ +K+++ R +
Sbjct: 312 DKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 371
Query: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER---KERRE 207
+ R RER+ R+ R + + K K + R RN+K++K+E+ER ERRE
Sbjct: 372 RRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRE 431
Query: 208 RKKE---RKKKEERK-KERQKDRQTNWREKERGK 237
R++ RK +R KE+ + T+ +EKE K
Sbjct: 432 RERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNK 465
Score = 119 bits (299), Expect = 2e-27
Identities = 67/208 (32%), Positives = 114/208 (54%), Gaps = 7/208 (3%)
Query: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
E+ +R RE ++ E ES + ER+ R R K R + +K + K
Sbjct: 161 EVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSR 220
Query: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE-ERE 155
R R ++ K KK+ K R S+ K + RE+ KE+ER KE +RE
Sbjct: 221 SHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDRE 280
Query: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215
KERER++ +++E K+ G+ ++ KE+E+ K +E K+R++ERE++ ++R KE++K+
Sbjct: 281 KEREREKEREKE-KERGKNKDRDKEREKDREKDKE---KDREREREKEHEKDRDKEKEKE 336
Query: 216 EERKKERQKDRQTNWREKERGKRERKER 243
++++KER+KDR EK K+++K R
Sbjct: 337 QDKEKEREKDRSKEIDEKR--KKDKKSR 362
Score = 117 bits (293), Expect = 9e-27
Identities = 60/213 (28%), Positives = 117/213 (54%), Gaps = 5/213 (2%)
Query: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90
+ G +E + TR + + +S +++R + + R R + R R++ ++ K
Sbjct: 180 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 239
Query: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
KK + R+ RR+ + +K K +++ KE+ R ++ +E+ER+ E++RE+ KER +
Sbjct: 240 KKRSKSRE-RRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 298
Query: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210
K +R+KERE+ K +E+ + E+E+E ++ KE++K + KER+K+R ++ +RKK
Sbjct: 299 K-DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 357
Query: 211 ERKKKEERKKERQKDRQTNWREKERGKRERKER 243
++K R R + R R +R R+ R
Sbjct: 358 DKK---SRTPPRSYNASRRSRSSSRERRRRRSR 387
Score = 115 bits (287), Expect = 5e-26
Identities = 55/207 (26%), Positives = 120/207 (57%), Gaps = 5/207 (2%)
Query: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKK 99
E E ++G + R R K R + R R++ + + R + + ++++R R K
Sbjct: 178 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQSKHRSRSHNRSRSRQKDRRRSK 236
Query: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEG-KERERKEERKREERKERERKKEEREKER 158
+K +K E ++ R + +++ + ++E KE+ER +E+ RE+ +ERE+ EREKE+
Sbjct: 237 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREK---EREKEK 293
Query: 159 ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEER 218
ER + K R++++ ++E+++++ +ER+K ++++KE+E+ + +ER+K+R K+ +
Sbjct: 294 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 353
Query: 219 KKERQKDRQTNWREKERGKRERKERKK 245
K+++ K +T R +R R ++
Sbjct: 354 KRKKDKKSRTPPRSYNASRRSRSSSRE 380
Score = 114 bits (285), Expect = 8e-26
Identities = 67/223 (30%), Positives = 122/223 (54%), Gaps = 15/223 (6%)
Query: 35 QSEIREREREIETRKEGKKERESERKKER---------REREK-RKREREKERKRERGKK 84
+ +I+E+ER E +E ++ERE ER+KE+ +EREK R++++EK+R+RER K+
Sbjct: 265 REKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKE 324
Query: 85 EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER 144
+K K++E+E+ K + ++++ E EKRKK +K S R R R+R R
Sbjct: 325 HEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 384
Query: 145 KERERKKEEREKERERKERKKRERKQVGEKEEERKEKER---KERKKRERNRKERK--KE 199
+ R + R + +++ + + K+++++EKER ER++RER+ RK +
Sbjct: 385 RSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 444
Query: 200 RERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
R+ KE+ E+ K++E KE +K+ + E +
Sbjct: 445 RDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 487
Score = 102 bits (253), Expect = 4e-22
Identities = 65/191 (34%), Positives = 103/191 (53%), Gaps = 18/191 (9%)
Query: 61 KERREREKRKREREK----ERKRERGKK-EKKGERKKEERERKKRRREKENKEGEEKEKR 115
KE E KR RE + + E GK E+KG R + K R K + +R
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHS------RR 210
Query: 116 KKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKE 175
K+ + K R R+ + R++ R + K+R + +E R+ R KR+ + KE
Sbjct: 211 KRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 270
Query: 176 EER-KEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234
+ER KEK+R++ ++RE KER+KE+ER + ++R KER+K E+ KE+ ++R+ REKE
Sbjct: 271 KERVKEKDREKERERE---KEREKEKERGKNKDRDKEREKDREKDKEKDRERE---REKE 324
Query: 235 RGKRERKERKK 245
K KE++K
Sbjct: 325 HEKDRDKEKEK 335
Score = 92.0 bits (227), Expect = 4e-19
Identities = 61/198 (30%), Positives = 109/198 (55%), Gaps = 8/198 (4%)
Query: 39 REREREIETRKEGKKERESERKKER-REREKRK-REREKERKRERGK-KEKKGERKKEER 95
R++ERE + K+ +K+RE ER+KE ++R+K K +E++KE++RE+ + KE +RKK+++
Sbjct: 301 RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK 360
Query: 96 ERKKRRREKENKEGEEKEK-RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
R R ++ + R+++ + R+ + K +RK R R R +K ++R
Sbjct: 361 SRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPR-SRNKKDKKR 419
Query: 155 EKERER-KERKKRERK-QVGEKEEERKEKERKERKKRERNRKERKKERERKERRE-RKKE 211
EKER+ ER++RER + + +R KE+ E+ KE KE + +E K+
Sbjct: 420 EKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKD 479
Query: 212 RKKKEERKKERQKDRQTN 229
+ EE K + + Q N
Sbjct: 480 APRTEENKIQHNGNCQLN 497
Score = 74.7 bits (182), Expect = 7e-14
Identities = 53/200 (26%), Positives = 90/200 (45%), Gaps = 33/200 (16%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK------ 92
RE+++E + +E +KE E +R KE+ + + +++EREK+R +E +K KK ++ +
Sbjct: 309 REKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY 368
Query: 93 --------EERERKKRRREKENKEGE----------------EKEKRKKKEKKERGRTSK 128
RER++RR ++ + K+ KK +KER S
Sbjct: 369 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHIS- 427
Query: 129 EGKERERKEE-RKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERK 187
E +ERER RK ++ + K E+ + KE K V KE + K+ R E
Sbjct: 428 ERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSV-SKEVDDKDAPRTEEN 486
Query: 188 KRERNRKERKKERERKERRE 207
K + N + E + E
Sbjct: 487 KIQHNGNCQLNEENLSTKTE 506
Score = 45.4 bits (106), Expect = 4e-05
Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 8/135 (5%)
Query: 12 KLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKR 71
K T + + S S+ ++ + R R T K K++ R ++ +KR
Sbjct: 360 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKR 419
Query: 72 EREKERKRERGKKEKKGERKKEERERK-KRRREKENKEGEEKEKRKKKEKKERGRTSKEG 130
E+E++ ER ++E+ +K +R K + EK + +EKE K+ + S
Sbjct: 420 EKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPD-------SSVS 472
Query: 131 KERERKEERKREERK 145
KE + K+ + EE K
Sbjct: 473 KEVDDKDAPRTEENK 487
Score = 43.1 bits (100), Expect = 2e-04
Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 5/105 (4%)
Query: 145 KERERKKEEREKERERKERKKRERKQ---VGEKEEERKEKERKERKKRERNRKERKKERE 201
K E + KE E ++ RE + + E K ERK + R R + + +
Sbjct: 146 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSK 205
Query: 202 RKERRERK--KERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
RR+R K R + R + RQKDR+ + ++ + R+ RK
Sbjct: 206 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRK 250
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 120 bits (302), Expect = 8e-28
Identities = 63/210 (30%), Positives = 113/210 (53%), Gaps = 3/210 (1%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
R R E +RE ER+KER+ E+ +EREKER+R R R+ RER
Sbjct: 277 RSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERH 336
Query: 99 KRRREKENKEGEEKEKRKKKEKK-ERGRTSKEGKERERKEERKREERKERERKKEEREKE 157
+ R +++G+ +++ +++EK+ ERGR ++ER ER++E + RER KE+R +
Sbjct: 337 RSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRG 396
Query: 158 RERKERKKRERKQVGEKEEER-KEKERKERKKRERNRKERKKERERKE-RRERKKERKKK 215
+++ K ++ ++++R +KE+K + R R RK R + R R +R R + ++K
Sbjct: 397 EVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKS 456
Query: 216 EERKKERQKDRQTNWREKERGKRERKERKK 245
+ K E ++ R +G+ + E+ K
Sbjct: 457 SKHKNESKEKSNKRSRSGSQGRTDSVEKSK 486
Score = 115 bits (289), Expect = 3e-26
Identities = 71/223 (31%), Positives = 124/223 (55%), Gaps = 20/223 (8%)
Query: 40 EREREIETRKEGKKERESERKKERRERE--KRKREREKERKRERGK-KEKKGERKKEERE 96
ERE+E + + KERE ER++ R +R+R R +ER R R + +++KG+R+ +RE
Sbjct: 296 EREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRE 355
Query: 97 RKK-----RRREKE------NKEGEEKEKRKKKEKKERGRTS-KEGKERERKEERKR--E 142
R+K RRR+++ N+ +E+E+ +++ K++R R +E K +E K++R+ +
Sbjct: 356 REKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDD 415
Query: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
+R ++ KK R + RERK R + + G++ R KE+ + K E K K+ R
Sbjct: 416 KRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSR-SKEKSSKHKNESKEKSNKRSRSG 474
Query: 203 KERRERKKERKKKEERKKERQKDRQTNWREKERG-KRERKERK 244
+ R E+ KK E ++K R+ + R KER KR+ + K
Sbjct: 475 SQGRTDSVEKSKKREHSPSKEKSRKRS-RSKERSHKRDHSDSK 516
Score = 114 bits (285), Expect = 8e-26
Identities = 61/210 (29%), Positives = 115/210 (54%), Gaps = 8/210 (3%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
R R + R+ ++ R +E RE E+E++R+R ++E K ER+KE R +
Sbjct: 261 RSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAK-EREKERRRSR 319
Query: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE---ERE 155
R E + +E+ + + + + + ++RER++E +R R++R+ KE ERE
Sbjct: 320 SIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNERE 379
Query: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215
KERER + +E++ GE EE++ ++++ +R+ R+ R +K E+K R R +ERK +
Sbjct: 380 KERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKK---EKKHSRSRSRERKHR 436
Query: 216 EERKKERQKDRQTNWREKERGKRERKERKK 245
R + R +++ R KE+ + + E K+
Sbjct: 437 -SRSRSRNAGKRSRSRSKEKSSKHKNESKE 465
Score = 113 bits (282), Expect = 2e-25
Identities = 73/229 (31%), Positives = 119/229 (51%), Gaps = 14/229 (6%)
Query: 31 QPGWQSEIREREREIETR-KEGKKE--RESERKKERREREKRKREREKERKRERGK-KEK 86
Q +I+ R R+I+ KEG +E R ER++ R R R R R R +E
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREG 285
Query: 87 KGER---KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143
G ++ ERE++++R E+E KE E++ +R + + R +ER R R R+
Sbjct: 286 HGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDR 345
Query: 144 RKERERKKEEREKERERKERKKR--ERKQVGEKEEERKEKERKERKKRERNRKERKKERE 201
+ +R + EREKE ER R+ R ++++ E+E+ER+ + +++R R E KK +E
Sbjct: 346 KGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKE 405
Query: 202 RK-ERRERKKERKKKEERKKERQKDRQTNWREKER----GKRERKERKK 245
K +RR R +R K+E+K R + R+ R + R GKR R K+
Sbjct: 406 DKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKE 454
Score = 106 bits (264), Expect = 2e-23
Identities = 64/213 (30%), Positives = 110/213 (51%), Gaps = 18/213 (8%)
Query: 35 QSEIRERERE---IETRKEGKKERESERKKERREREKRKREREKERKRERGK-KEKKGER 90
+S RER R RK +++R+ ER+KE +R R+ +KER ER K +E+ ER
Sbjct: 329 RSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRER 388
Query: 91 KKEER-----ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER-------KEE 138
KE+R E KK + +K+++ + ++ KKEKK S+E K R R K
Sbjct: 389 SKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRS 448
Query: 139 RKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK 198
R R + K + K E +EK +R + R EK ++R+ KE+ ++ KER
Sbjct: 449 RSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSH 508
Query: 199 ERERKERRER--KKERKKKEERKKERQKDRQTN 229
+R+ + +++ K +R++ + ++E Q+ + N
Sbjct: 509 KRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKN 541
Score = 86.3 bits (212), Expect = 2e-17
Identities = 47/178 (26%), Positives = 90/178 (50%), Gaps = 7/178 (3%)
Query: 39 REREREIETRKEGKKERESERKKERRER---EKRKREREKERKRERGKKEKKGERKKEER 95
R+ ++E +E ++ER ER KE+R R E++K + +K+ +R R K + KK R
Sbjct: 368 RDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSR 427
Query: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSK-EGKERERKEERKREE-RKERERKKEE 153
R + R+ + KR + KE+ K E KE+ K R + R + K ++
Sbjct: 428 SRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKK 487
Query: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKE 211
RE +++ +KR R + E+ +R + K++ + R+ + E+E +E++ + K+
Sbjct: 488 REHSPSKEKSRKRSRSK--ERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543
Score = 79.7 bits (195), Expect = 2e-15
Identities = 49/174 (28%), Positives = 91/174 (52%), Gaps = 14/174 (8%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRK-REREKERKRERGKKEKKGERKKEERER 97
+ERER E KE + E E KK + +++ R+ R+ +++ KKEKK R + RER
Sbjct: 380 KERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRD-----SKKEKKHSRSR-SRER 433
Query: 98 KKRRREKENKEGEEKEKR-KKKEKKERGRTSKEGKERERKEERKREERKERERKKE---E 153
K R R + G+ R K+K K + + ++ +R R + R + E+ +K+E
Sbjct: 434 KHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPS 493
Query: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207
+EK R+R K+R K+ + K++ K ++R ++ ++ +E++ K + E
Sbjct: 494 KEKSRKRSRSKERSHKR---DHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDE 544
Score = 42.7 bits (99), Expect = 3e-04
Identities = 22/100 (22%), Positives = 46/100 (46%), Gaps = 13/100 (13%)
Query: 33 GWQSEIREREREIETRKEGKKERES-------------ERKKERREREKRKREREKERKR 79
G +S R +E+ + + E K++ E+ K+R +++ R++ R +
Sbjct: 445 GKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSK 504
Query: 80 ERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKE 119
ER K + K + + +RR + +E +EK+ + K E
Sbjct: 505 ERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDE 544
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 117 bits (294), Expect = 7e-27
Identities = 63/215 (29%), Positives = 140/215 (65%), Gaps = 8/215 (3%)
Query: 34 WQSE--IREREREIETRKEGKKERESE-RKKERREREKRKREREKERKRERGK---KEKK 87
W+ E +R++E+++ ++E E++ R+KE R RE++K +++E+ RE K +EKK
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548
Query: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKEKK--ERGRTSKEGKERERKEERKREERK 145
++E+ ++R RE+E K EE+E +++E+K E+ +E +E+ ++E K +E++
Sbjct: 549 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 608
Query: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER 205
E+ ++EE+ E+E +++ + + + + E+EE+ +E+E K ++ E+ R++ +K RE++E+
Sbjct: 609 EKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
Query: 206 RERKKERKKKEERKKERQKDRQTNWREKERGKRER 240
+ ++E+ +++E K + Q+++ EK RG+ E+
Sbjct: 669 MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEK 703
Score = 116 bits (290), Expect = 2e-26
Identities = 71/219 (32%), Positives = 136/219 (62%), Gaps = 9/219 (4%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E RE+E + RK+ +K E + +E + R++E EK R++E+ +E++ E +++
Sbjct: 237 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE-EKMRRQEKRLREQEKELREQ 295
Query: 94 ERE--RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER--KEERKREERKERER 149
E+E +K+ RE+E + E++EK ++E+K R + K ++ ER ++E++ E++++ R
Sbjct: 296 EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355
Query: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER- 208
+EER E++ + R+K ER + EK E++EK ++E + RER +K R++E +E+ E+
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKM 415
Query: 209 -KKERKKKEERKKERQKDRQTNWREK--ERGKRERKERK 244
K+E E+ +KE Q+ R +EK E+ K + +E K
Sbjct: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454
Score = 115 bits (289), Expect = 3e-26
Identities = 59/210 (28%), Positives = 135/210 (64%), Gaps = 5/210 (2%)
Query: 34 WQSEIREREREIETRKEGKK-ERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
W+ + R RE+E R++ K ++E + ++E++ +E+ K+ ++E K ++E+ ER+K
Sbjct: 510 WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMR--EEERMREREK 567
Query: 93 EERERKKRRREKENKEGEEKEKRKKKEKK--ERGRTSKEGKERERKEERKREERKERERK 150
+ RE ++ RE+E K E++EK +++E+K E+ +E +E+ ++E K E++E ++
Sbjct: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627
Query: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210
+E+ E E++E+ + + +++ E+EE+ +E+E K R++ E+ + + +K RE++E+ + ++
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687
Query: 211 ERKKKEERKKERQKDRQTNWREKERGKRER 240
E+ +++E K Q+++ EK G+ E+
Sbjct: 688 EKMREQEEKMRGQEEKMWGQEEKMWGQEEK 717
Score = 114 bits (285), Expect = 8e-26
Identities = 64/227 (28%), Positives = 144/227 (63%), Gaps = 15/227 (6%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKRERE-KERKRERGKKEKKGERKK 92
W+ E R RE+E + R++ +K R E++ +E+E R++E+E +E+K+ R ++E+ E+++
Sbjct: 258 WRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEE 317
Query: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER----------KEERKRE 142
+ E++++ RE+E K ++E+ ++EK+ R + K + ER KEER RE
Sbjct: 318 KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE 377
Query: 143 ERK--ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERK--ERKKRERNRKERKK 198
+ K E+E K +E E+ RER+++ + E + + E+EE+ +++E E++++E ++ +
Sbjct: 378 QEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 437
Query: 199 ERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
++E+ +E+ +E+++K ++E+ +D++ W ++++ R+ K R++
Sbjct: 438 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
Score = 110 bits (276), Expect = 9e-25
Identities = 63/221 (28%), Positives = 137/221 (61%), Gaps = 11/221 (4%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKER---REREKRKREREKERKRERGKKEKKGER 90
W+ + R RE+E R++ K + E+ +E REREK+ RE E+ + + K +K+ E
Sbjct: 362 WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 421
Query: 91 --KKEERERKKRRREKENKEGEEKEKRKKKEKK-----ERGRTSKEGKERERKEERKREE 143
++EE+E +++R ++ ++ E+EK +++E+K E+ R +E +E+K R+ +
Sbjct: 422 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 481
Query: 144 RKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERK 203
R++ ++ E+ EK R+++++ + +++ E++E +EKE + R++++ ++E K E+K
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKK 541
Query: 204 ERRERKKERKKKEE-RKKERQKDRQTNWREKERGKRERKER 243
+ + KK ++E+ R++ER ++R+ RE+E RE++E+
Sbjct: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 582
Score = 110 bits (274), Expect = 1e-24
Identities = 61/214 (28%), Positives = 138/214 (64%), Gaps = 9/214 (4%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+ E+RE+E+E+ +K+ +++ E +++E + E+ ++ RE+E K R ++E+ E++K+
Sbjct: 289 EKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWR-QEERLWEQEKQM 347
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
RE++++ R++E + E+ E+ ++KE++ R E ++ +EE+ +EE + RER+K+ R
Sbjct: 348 REQEQKMRDQEERMWEQDERLREKEERMR-----EQEKMWEQEEKMQEEERIREREKKMR 402
Query: 155 EKE---RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKE 211
E+E RE++E+ +++ + + E+EE+ +++R +K + +E+ +E+E K + +K
Sbjct: 403 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 462
Query: 212 RKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
R ++E +E++ RQ RE+E E++E+ +
Sbjct: 463 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496
Score = 110 bits (274), Expect = 1e-24
Identities = 75/237 (31%), Positives = 140/237 (59%), Gaps = 28/237 (11%)
Query: 34 WQSEIREREREIETRKEGKKERESERK---KERREREKRKREREKERKRERGKKEKKGER 90
W+ E R E+E + R++ +K R+ E + ++ R REK +R RE+E+ E+ +K ++ ER
Sbjct: 334 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEER 393
Query: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKE--------------GKERERK 136
RER+K+ RE+E E++EK +K+E+ + KE +E+ ++
Sbjct: 394 I---REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 450
Query: 137 EERKREERKERERKKEE---REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR 193
+E K E++E+ R +EE +EK+ R+E+ + + Q+ E+EE+ +++E+K + ER
Sbjct: 451 QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMW 510
Query: 194 KERKKERERKER-RERKK----ERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
++ ++ RE++ER RE+KK E K +EE+K + Q+ + + EK R + +ER+K
Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREK 567
Score = 110 bits (274), Expect = 1e-24
Identities = 75/234 (32%), Positives = 144/234 (61%), Gaps = 24/234 (10%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREK-----------ERKRERG 82
W+ E + RE+E + R + +ER E+ + RE+E+R RE+EK ER RER
Sbjct: 341 WEQEKQMREQEQKMRDQ--EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRERE 398
Query: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142
KK ++ E E+E K +++E+ E EEKE ++++ +++ + ++ K +E++E+ +
Sbjct: 399 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 458
Query: 143 ERKERERKKE-EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERE 201
E K R++++ +EK+ R+E+ + + Q+ E+EE+ +++E+K + ER ++ ++ RE
Sbjct: 459 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE 518
Query: 202 RKER-RERKK----ERKKKEERKKERQK----DRQTNWREKER-GKRERKERKK 245
++ER RE+KK E K +EE+K + Q+ D++ RE+ER +RE+K R++
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572
Score = 110 bits (274), Expect = 1e-24
Identities = 71/229 (31%), Positives = 143/229 (62%), Gaps = 20/229 (8%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERRER---EKRKREREKERKRERGKK----EKK 87
Q E R RERE + R+E + RE E K +++E E+ ++E +++R E+ +K EK
Sbjct: 389 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 448
Query: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK---REER 144
E++++ E++++ R++E G+EK+ ++++ +E+ E +E+ R +E+K +EER
Sbjct: 449 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 508
Query: 145 ----KERERKKEEREKERER---KERKKRERKQVGEKEE---ERKEKERKERKKRERNRK 194
ER R+KEER +E+++ +E K RE K+ E+E+ +++EK R+E + RER +K
Sbjct: 509 MWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568
Query: 195 ERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
R++E +E+ E+ +E+++K ++E+ +++ +E+E E++E+
Sbjct: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617
Score = 107 bits (268), Expect = 7e-24
Identities = 69/220 (31%), Positives = 129/220 (58%), Gaps = 22/220 (10%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
WQ E + RE E +T+++ KK + E K RE+ER RER KK ++ E
Sbjct: 530 WQQEEKMRE-EKKTQEQEKKTWDQEEKM-----------REEERMREREKKMREEEEMMR 577
Query: 94 ERERKKRRREKENKEGEEK--EKRKKKEKKERGRTSKEGKERERKEERKREERKE----- 146
E+E K + +E++ +E EEK E+ +K +++E +E K E++EE K +E++E
Sbjct: 578 EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQ 637
Query: 147 RERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERR 206
E+ +E+ EK E++E+ + + +++ E+EE+ + +E K R++ E+ + + +K RE++E+
Sbjct: 638 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKM 697
Query: 207 ERKKERKKKEERKKERQKDR---QTNWREKERGKRERKER 243
++E+ +E K Q+++ Q REKE R++KE+
Sbjct: 698 RGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEK 737
Score = 107 bits (267), Expect = 9e-24
Identities = 67/226 (29%), Positives = 139/226 (61%), Gaps = 19/226 (8%)
Query: 36 SEIREREREIETRKEGKK--ERESERKKERRE---------REKRKREREKERKRERGKK 84
+E++E+ R E+ K + +E +RK ER + + + R++E RE+ KK
Sbjct: 190 AELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK 249
Query: 85 EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER 144
+K E K +E + R +E + +E EEK +R++K +E+ + +E +E+E +E++K E+
Sbjct: 250 IRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELRE-QEKELREQKKLREQ 308
Query: 145 KERERKKEER-----EKERERKERKKRERKQVGEKEEERKEKERKERKKRER--NRKERK 197
+E+ +++EE+ EK RE++E+ R+ +++ E+E++ +E+E+K R + ER + ER
Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 368
Query: 198 KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
+E+E + R + K ++++ +++ER ++R+ RE+E RE++E+
Sbjct: 369 REKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEK 414
Score = 103 bits (258), Expect = 1e-22
Identities = 63/203 (31%), Positives = 125/203 (61%), Gaps = 11/203 (5%)
Query: 52 KKERESERKKERREREKRKREREKERKRE---RGKKEKKGERKKEERERKKRRREKENKE 108
++E + KK R++ EK R+ E+ R++E R ++EK ++K RE++K RE+E +
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
Query: 109 GEEKEKRKKKE---KKERGRTSKEGKERERKEERKREERKERERKKEEREKE---RERKE 162
E+K+ R+++E ++E +E K RE++E+ R+E + E++K+ RE+E R+++E
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Query: 163 RKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKER 222
R + +++ EKEE +E+E+ ++ + +ER +ERE+K R E +E +++E K ++
Sbjct: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE--EETMREQEEKMQK 417
Query: 223 QKDRQTNWREKERGKRERKERKK 245
Q++ EKE ++ E+K+
Sbjct: 418 QEENMWEQEEKEWQQQRLPEQKE 440
Score = 103 bits (257), Expect = 1e-22
Identities = 70/229 (30%), Positives = 140/229 (61%), Gaps = 23/229 (10%)
Query: 35 QSEIREREREIETRKEG-----KKERESERKKERRER---EKRKREREKERKRERGKKEK 86
Q ++RE+E +++ ++E +K RE E K R+E E+ K+ RE+E+K R ++E+
Sbjct: 302 QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM-RDQEER 360
Query: 87 KGERKKEERERKKRRREKENKEGEEKEKRKKKEK-KERGRTSKEGKERERKEERKREERK 145
E+ + RE+++R RE+E K E++EK +++E+ +ER + +E +E R++E K ++++
Sbjct: 361 MWEQDERLREKEERMREQE-KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 419
Query: 146 ERERKKEEREKERERKERKKR---ERKQVGEKEEERKEKERK---------ERKKRERNR 193
E ++EE+E +++R +K E++++ E+EE+ E+E K + KK R
Sbjct: 420 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 479
Query: 194 KERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
K R++E + E+ E+ +++++K ++ER ++ REKE RE+K+
Sbjct: 480 KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKK 528
Score = 102 bits (255), Expect = 2e-22
Identities = 66/217 (30%), Positives = 134/217 (61%), Gaps = 20/217 (9%)
Query: 46 ETRKEGKKERESERKKERREREKRKREREKERKRERGK----KEKKGERKKEERERKKRR 101
E +K+ + +E R E + E + +E +RK ER K + + ++E +++
Sbjct: 184 ELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL 243
Query: 102 REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERK 161
RE+E K +++EK ++E++ R +EGK RE++E+ +R+E++ RE++KE RE+E+E +
Sbjct: 244 REQEKKIRKQEEKMWRQEERLR---EQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
Query: 162 ERKK-RER-KQVGEKEEERKEKERKERKKRERN-RKERKKERERKERRERKKERKKKEER 218
E+KK RE+ +Q+ E+EE+ E+E K R++ E+ R+E + + K+ RE++++ + +EER
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Query: 219 ----------KKERQKDRQTNWREKERGKRERKERKK 245
K+ER ++++ W ++E+ + E + R++
Sbjct: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER 397
Score = 101 bits (251), Expect = 7e-22
Identities = 57/225 (25%), Positives = 137/225 (60%), Gaps = 16/225 (7%)
Query: 34 WQSEIRE-REREIETRKEGKKERESERKKERR--EREKRKREREK----ERKRERGKKEK 86
W+ E +E +++ + +KE E+E +++E + E+E++ R++E+ E+K R +K +
Sbjct: 423 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 482
Query: 87 KGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKE 146
+ E + E+E K R +E++ + EE+ + + +E+ +E K+ ++EE+ REE+K
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT 542
Query: 147 RERKKE---------EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERK 197
+E++K+ E E+ RER+++ + E + + E+EE+ +E+E K R++ E+ ++ +
Sbjct: 543 QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEE 602
Query: 198 KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
K +E++E+ ++E+ ++E + + Q+ + W ++E+ + + ++
Sbjct: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647
Score = 99.0 bits (245), Expect = 3e-21
Identities = 65/220 (29%), Positives = 139/220 (63%), Gaps = 14/220 (6%)
Query: 35 QSEIREREREIETRKE-GKKERESERKKERREREKRKREREKERKRERGKKEKKGER--K 91
+ +I E+E +I ++E +E++ R+++ RE+E + E+E++ + + K + ER +
Sbjct: 452 EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWE 511
Query: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER-KERERK 150
++ER R+K R +E K+ ++E++ ++EKK + +E K +++E+ + EER +ERE+K
Sbjct: 512 QDERLREKEERMREQKKMWQQEEKMREEKKTQ---EQEKKTWDQEEKMREEERMREREKK 568
Query: 151 -KEEREKERERKERKKRERKQVGEKEEERKEKERK----ERKKRERNRK--ERKKERERK 203
+EE E RE++E+ + + +++ E+EE+ E+E K E K E+ K E+++E + +
Sbjct: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Query: 204 ERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
E+ E E+++K + ++E+ +++ RE+E RE++E+
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
Score = 97.8 bits (242), Expect = 7e-21
Identities = 53/199 (26%), Positives = 121/199 (60%), Gaps = 1/199 (0%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKR-ERGKKEKKGERKKE 93
+ ++RE ER E K+ ++E E R++E + +E+ ++ RE+E K E+ +K ++ E K
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 612
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
E+E K +E+E+K E++E ++E+K + + K ++ E+ E++ + R++ E+ + +
Sbjct: 613 EQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 672
Query: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
EK RE++E+ + + +++ E+EE+ + +E K + E+ + +K ++E RE+++ +
Sbjct: 673 EEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIR 732
Query: 214 KKEERKKERQKDRQTNWRE 232
++E+ +ER + + E
Sbjct: 733 DQKEKMQERLPEHEERCSE 751
Score = 83.2 bits (204), Expect = 2e-16
Identities = 51/206 (24%), Positives = 117/206 (56%), Gaps = 1/206 (0%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
++ +R IE + + E + E+ K++ + +++ R + +K E + +E K
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
Query: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER 158
++ + + + ++E + +E +++ RK+E K ++ER R++E + +E+
Sbjct: 215 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 274
Query: 159 ERKERKKRERKQVGEKEEERKEKERKERKK-RERNRKERKKERERKERRERKKERKKKEE 217
E K R++ +R + EKE +EKE +E+KK RE+ + +++E + E+ E+ +E+++K
Sbjct: 275 EEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMW 334
Query: 218 RKKERQKDRQTNWREKERGKRERKER 243
R++ER +++ RE+E+ R+++ER
Sbjct: 335 RQEERLWEQEKQMREQEQKMRDQEER 360
Score = 67.4 bits (163), Expect = 1e-11
Identities = 43/147 (29%), Positives = 90/147 (61%), Gaps = 7/147 (4%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E + E+E E + + ++E E++++ +E+E++ E+E E+ RE+ +K ++ E K +
Sbjct: 612 WEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE-EKMREQEEKMREQEEKMQ 670
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
+E K R +E E +G+E EK +++E+K RG+ K + EE+ + ++ ++E
Sbjct: 671 GQEEKMREQE-EKMQGQE-EKMREQEEKMRGQEEKMWGQ----EEKMWGQEEKMWGQEEM 724
Query: 154 REKERERKERKKRERKQVGEKEEERKE 180
REKE +++K++ ++++ E EE E
Sbjct: 725 REKEERIRDQKEKMQERLPEHEERCSE 751
Score = 62.8 bits (151), Expect = 3e-10
Identities = 43/175 (24%), Positives = 92/175 (52%), Gaps = 6/175 (3%)
Query: 77 RKRERGKKEKKGERKKEERE--RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERE 134
+K +R +E ER E R E+ K+ E +++ + + E+ KE +
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
Query: 135 RKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRK 194
RK ER + + + + E R+ +E +++E+K ++E+ +++ER ++ + +
Sbjct: 215 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 274
Query: 195 ERKKERERKERRERKKERKKKE----ERKKERQKDRQTNWREKERGKRERKERKK 245
E K R+ K RE++KE +++E E+KK R+++ Q +E++ ++E K R++
Sbjct: 275 EEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQ 329
Score = 35.8 bits (81), Expect = 0.035
Identities = 24/81 (29%), Positives = 47/81 (58%), Gaps = 4/81 (4%)
Query: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
G + ++RE+E +++ ++E +E+E +K R + EK + EK +E ++ R+K
Sbjct: 671 GQEEKMREQEEKMQGQEEKMREQE---EKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREK 727
Query: 93 EERERKKRRREKEN-KEGEEK 112
EER R ++ + +E E EE+
Sbjct: 728 EERIRDQKEKMQERLPEHEER 748
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 117 bits (292), Expect = 1e-26
Identities = 61/215 (28%), Positives = 142/215 (66%), Gaps = 8/215 (3%)
Query: 35 QSEIREREREIETRKEG---KKERESERKKERREREK---RKREREKERKRERGKKEKKG 88
+ E+RE+E++I ++E ++ER E++ + RE+E+ R+ +R +E+++E ++EK+
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL 337
Query: 89 ERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE 148
+KE RE++++ +E+E K E++EK +++E+K + + ++ ++ E++++ R + E
Sbjct: 338 REQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 397
Query: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
R E+ E+ RE++ER + + K + E+ R+EK+ +E++K+ R+++E+ +E ER RE+
Sbjct: 398 RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREK 457
Query: 209 K--KERKKKEERKKERQKDRQTNWREKERGKRERK 241
K +E + E++++ QK + W ++E+ ++++
Sbjct: 458 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 492
Score = 115 bits (287), Expect = 5e-26
Identities = 73/221 (33%), Positives = 136/221 (61%), Gaps = 14/221 (6%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E R RE+E + R++ +E+ ++K RE+EK RE+EKE + ++ +E+ E + +
Sbjct: 296 WRQEERLREQEGKMREQ--EEKMWRQEKRLREQEKELREQEKELREQKELREQ--EEQMQ 351
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
E+E K +E++ +E EEK R+++ E+ + +E +++ R +E + E+ ER R+KEE
Sbjct: 352 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 411
Query: 154 REKERER---KERKKRERKQVGEKEEERKEKERK---ERKKRERNRKERKKERERKERRE 207
R +E+E+ + K RE K++ E+E++ +++E K E + RER +K R++E +E+ E
Sbjct: 412 RMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEE 471
Query: 208 R--KKERKKKEERKKERQKDRQTNWREK--ERGKRERKERK 244
+ K+E E+ +KE Q+ R +EK E+ K + +E K
Sbjct: 472 KMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Score = 114 bits (286), Expect = 6e-26
Identities = 57/217 (26%), Positives = 143/217 (65%), Gaps = 7/217 (3%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+ E+RE+E+E+ +KE +++ E +++E + E+ ++ RE+E K R ++E+ E++K+
Sbjct: 327 EKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWR-QEERLWEQEKQM 385
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
RE++++ R++E + E+ E+ ++KE++ R + + + +EE+K +E++++ R +EE+
Sbjct: 386 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445
Query: 155 EKERER---KERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER---RER 208
+E ER +E+K RE ++ ++EE+ +K+ + ++E ++++ E+KE+ +E+
Sbjct: 446 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 505
Query: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+E+++K ++E+ +D++ W ++++ R+ K R++
Sbjct: 506 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Score = 109 bits (272), Expect = 2e-24
Identities = 71/231 (30%), Positives = 141/231 (61%), Gaps = 25/231 (10%)
Query: 35 QSEIREREREIETRK--------EGKKERESERKKERREREKRKRE------REKERKRE 80
Q ++E +R++E K +E +++E RE+EK+ R+ R++ER RE
Sbjct: 245 QLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLRE 304
Query: 81 RGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK 140
+ K ++ E K +E++ R +EKE +E +EKE R++KE +E+ +E +E+ ++E K
Sbjct: 305 QEGKMREQEEKMWRQEKRLREQEKELRE-QEKELREQKELREQEEQMQEQEEKMWEQEEK 363
Query: 141 REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERK--- 197
E++E+ ++EER E+E++ R++ ++ + ++EE E++ + R+K ER R++ K
Sbjct: 364 MREQEEKMWRQEERLWEQEKQMREQEQKMR--DQEERMWEQDERLREKEERMREQEKMWE 421
Query: 198 ---KERERKERRERKKERKKKEER--KKERQKDRQTNWREKERGKRERKER 243
K RE K+ +E++K+ + +EE+ ++ER ++R+ RE+E RE++E+
Sbjct: 422 QVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK 472
Score = 108 bits (271), Expect = 3e-24
Identities = 64/240 (26%), Positives = 138/240 (57%), Gaps = 30/240 (12%)
Query: 34 WQSEIREREREIETRKEGK--------KERESERKKERREREKRKREREKERKRERGKKE 85
W+ + R RE+E R++ K +E + +++E++ R++ ++ +E+ER RER KK
Sbjct: 400 WEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKM 459
Query: 86 KKGERKKEERERKKRRREKENKEGEEKE--------------KRKKKEKKERGRTSKEGK 131
++ E E+E K +++E+ E EEKE +++K +++E +E K
Sbjct: 460 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 519
Query: 132 ERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRER 191
R+++E +E++ R+ K E+E + +E K R+++Q +EER EK+ +E++K+
Sbjct: 520 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTW 579
Query: 192 NRKERKKERERKERRERK--------KERKKKEERKKERQKDRQTNWREKERGKRERKER 243
+++E+ +E ER RE+K +E+++K + ++E+ ++++ E+E +E++E+
Sbjct: 580 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK 639
Score = 108 bits (270), Expect = 4e-24
Identities = 69/222 (31%), Positives = 135/222 (60%), Gaps = 19/222 (8%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Q E+ +E E+ R++ KK R+ E K R+E R++E + RE+ +K + E++ E
Sbjct: 271 QEEMWRQEEEL--REQEKKIRKQEEKMWRQEERLREQEG---KMREQEEKMWRQEKRLRE 325
Query: 95 RERKKRRREKENKE-----------GEEKEKRKKKEKKERGRTSKEGKERER--KEERKR 141
+E++ R +EKE +E E++EK ++E+K R + K ++ ER ++E++
Sbjct: 326 QEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQM 385
Query: 142 EERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER-KKER 200
E++++ R +EER E++ + R+K ER + EK E+ EK R+E+K +E+ +K R ++E+
Sbjct: 386 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445
Query: 201 ERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
++E R R++E+K +EE + R+++ + +E+ ++E KE
Sbjct: 446 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 487
Score = 108 bits (269), Expect = 6e-24
Identities = 58/223 (26%), Positives = 133/223 (59%), Gaps = 11/223 (4%)
Query: 34 WQSEIREREREIETRKEGKKERESERKK-ERREREKRKREREKERKRERGKKEKKGERKK 92
W+ E R E+E + R++ +K R+ E + E+ ER + K ER +E+++ + EK E KK
Sbjct: 372 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKK 431
Query: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
+ + KK R ++E + EE+ + ++K+ +E T +E +E+ +K+E E++E+E +++
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ 491
Query: 153 ----------EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
E+EK +E++E+ + +++ ++EE ++++ R+++ R ++++ E+E
Sbjct: 492 RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEE 551
Query: 203 KERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
K R + +K ++E +K+ Q+ + W ++E+ + E + R++
Sbjct: 552 KMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER 594
Score = 107 bits (267), Expect = 9e-24
Identities = 65/218 (29%), Positives = 134/218 (61%), Gaps = 12/218 (5%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E + RE+E + ++ +K R+ E+K +E K+ +E+E+K +++ + E +
Sbjct: 534 WRQE-KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMR 592
Query: 94 ERERKKRRREKENKEGEEK--EKRKKKEKKERGRTSKEGKERERKEERKREERK--ERER 149
ERE+K R E+ +E EEK E+ +K +++E +E K +E++E+ +E K E+E
Sbjct: 593 EREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 652
Query: 150 KKEEREKERERKER-----KKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKE 204
K E+++ E+KE+ K +E++++ E+EE+ E+E+ E+K +E+ +K +E+ R+E
Sbjct: 653 KMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREE 712
Query: 205 RRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
R++E+K +EE +E ++++ +E+E +E++E
Sbjct: 713 ESMREREKKMREE--EEMMREQEEKMQEQEEKMQEQEE 748
Score = 105 bits (263), Expect = 3e-23
Identities = 66/235 (28%), Positives = 140/235 (59%), Gaps = 27/235 (11%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREK----------ERKRERGK 83
W+ E + RE+E + R + +ER E+ + RE+E+R RE+EK E+K + +
Sbjct: 379 WEQEKQMREQEQKMRDQ--EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQE 436
Query: 84 KEKKGERKKEERERKKRRREKENKEGEE--KEKRKKKEKKERGRTSKEGKE-RERKEERK 140
K+ + + +K + E + R REK+ +E EE +E+ +K +K+E +E KE ++++ +
Sbjct: 437 KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496
Query: 141 REERKERERKKEEREKERERKERKKRERKQVGE-----KEEERKEKERKERKKRERNRKE 195
+E+ E+E+ +E+ EK E++E+ + + + G+ ++E+ +E+E + ++ E+ R +
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 556
Query: 196 RKKERERKERRERKKERKKKEE-------RKKERQKDRQTNWREKERGKRERKER 243
+K +++ER E+K + ++K+ R++ER ++R+ RE+E RE++E+
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 611
Score = 105 bits (262), Expect = 4e-23
Identities = 62/222 (27%), Positives = 139/222 (62%), Gaps = 15/222 (6%)
Query: 37 EIREREREIETRKEGKKERESERKKER-REREKRKREREKERKRERGKKEKKGER--KKE 93
++RE ++ E K+ + + E +++ER REREK+ RE E+ + + K +K+ E ++E
Sbjct: 425 KMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKK-----ERGRTSKE--GKERERKEERKREERKE 146
E+E +++R ++ ++ E+EK +++E+K E+ R +E G+E++ + K E+++
Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 544
Query: 147 RERKKEEREKERERKERKKRERKQVGEKEEERK-----EKERKERKKRERNRKERKKERE 201
+ ++EE+ +++E+K + ER + +E+E+K EK R+E + RER +K R++E
Sbjct: 545 QMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 604
Query: 202 RKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
+E+ E+ +E+++K + ++E+ +++ +E+E E++E+
Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEK 646
Score = 104 bits (260), Expect = 6e-23
Identities = 70/231 (30%), Positives = 135/231 (58%), Gaps = 25/231 (10%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERRER-----------EKRKREREKERKRERGK 83
+ E R RERE + R+E + RE E K + +E ++ K + ++E+ E+ +
Sbjct: 586 REEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645
Query: 84 KEKKGERKKEERERKKRRREK--ENKEGEEKEKRKKKEKK--ERGRTSKEGKERERK--- 136
K + E K E++R ++EK E+++ +E+EK +++E+K E+ + K+ +E+E+K
Sbjct: 646 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWD 705
Query: 137 EERKREERKERERKKEEREKE---RERKERKKRERKQVGEKEEERKEKERK----ERKKR 189
+E+ REE RER+K+ RE+E RE++E+ + + +++ E+EEE E+E K E K
Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMW 765
Query: 190 ERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRER 240
E+ R +KE+ + + +++E+ ++E K Q+++ EK RG+ E+
Sbjct: 766 EQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEK 816
Score = 103 bits (257), Expect = 1e-22
Identities = 72/257 (28%), Positives = 149/257 (57%), Gaps = 47/257 (18%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERRER---EKRKREREKERKRERGKKEKKGERK 91
Q E R RERE + R+E + RE E K +++E E+ ++E +++R E+ +K + E+
Sbjct: 447 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 506
Query: 92 KEERE-----------------------RKKRRREKENKEGEEKEKRKKKEKK---ERGR 125
+E+ E R+++ RE+E++ E++EK + +E+K + R
Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 566
Query: 126 TSKEGKERERK----EERKREERKERERKKEEREKE---RERKERKKRERKQVGEKEEER 178
K+ +E+E+K EE+ REE + RER+K+ RE+E RE++E+ + + +++ E+EE+
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM 626
Query: 179 KEKERKERKKRER--NRKERKKERERK--------ERRERKKERKKKEERKKERQKDRQT 228
E+E K +++ E+ ++E+ E+E K E++E+ E +K +E++K ++++ +
Sbjct: 627 WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKI 686
Query: 229 NWREKERGKRERKERKK 245
W +++ K+ +++ KK
Sbjct: 687 -WEQEKMEKKTQEQEKK 702
Score = 102 bits (254), Expect = 3e-22
Identities = 64/222 (28%), Positives = 143/222 (64%), Gaps = 13/222 (5%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREK----ERKRERGKKEKKGE 89
W+ E E+ RE E + ++ER E++K+ RE+E++ R++E+ + +R R K+E+ E
Sbjct: 358 WEQE--EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE 415
Query: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
++K + +K R EK+ +E +EK+ R ++EK + +E +++ R+EE E++E+ +
Sbjct: 416 QEKMWEQVEKMREEKKMQE-QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQ 474
Query: 150 KKEEREKERERKERKKR---ERKQVGEKEEERKEKERK--ERKKRERNRKERKKERERKE 204
K+EE E+E KE +++ E+K+ ++E+ +E+E K E++++ R+++E + ++
Sbjct: 475 KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 534
Query: 205 RRERKKERKKKEERKKERQKDR-QTNWREKERGKRERKERKK 245
R+E+ +E++ + ++E+ +D+ Q W ++ER +++ +E++K
Sbjct: 535 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEK 576
Score = 100 bits (250), Expect = 9e-22
Identities = 55/224 (24%), Positives = 141/224 (62%), Gaps = 16/224 (7%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E + R++E E + KK E+ +E+ ++ + E+ ++++++ +E++ E+K +
Sbjct: 514 WEQEEKIRDQE-EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQ 572
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
E+E+K +E++ +E EE+ + ++K+ +E +E +E+ +++E K +E++E+ ++EE
Sbjct: 573 EQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEE 631
Query: 154 REKERERK-----------ERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
+ +E+E K E K E++++ E++E+ E E+ + +++ + ++E+ E+E+
Sbjct: 632 KMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEK 691
Query: 203 KERRERKKERK---KKEERKKERQKDRQTNWREKERGKRERKER 243
E++ +++E+K +++ R++E ++R+ RE+E RE++E+
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEK 735
Score = 100 bits (249), Expect = 1e-21
Identities = 55/202 (27%), Positives = 130/202 (64%), Gaps = 7/202 (3%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+ + +E+E++ ++E +E E R++E++ RE+ + RE+E K + ++EK E++++
Sbjct: 568 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE-QEEKMQEQEEKM 626
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
E++++ +E+E K E++EK ++E+K + +++E+ E ++ + +E+ +++EE+
Sbjct: 627 WEQEEKMQEQEEKMWEQEEKMWEQEEK-MWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK 685
Query: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
E+E+ E+K +E+ EK+ +EK R+E RER +K R++E +E+ E+ +E+++
Sbjct: 686 IWEQEKMEKKTQEQ----EKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741
Query: 215 K-EERKKERQKDRQTNWREKER 235
K +E+++E + + W ++E+
Sbjct: 742 KMQEQEEEMWEQEEKMWEQEEK 763
Score = 99.8 bits (247), Expect = 2e-21
Identities = 53/211 (25%), Positives = 129/211 (61%), Gaps = 4/211 (1%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKRER--EKERKRERGKKEKKGERK 91
W+ E + +E+E + ++ +K E E K ++R ++E+ E E+ +E+ K +++ E+
Sbjct: 627 WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKI 686
Query: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
E+ + +K+ +E+E K ++++ R+++ +ER + +E +E R++E K +E++E+ +++
Sbjct: 687 WEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 746
Query: 152 EEREKERERKERKKRERKQVGEKEEERKEK--ERKERKKRERNRKERKKERERKERRERK 209
EE E+E K ++ E+ ++ E+KEK E ++ +++E+ ++ +K R+++E+ +
Sbjct: 747 EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ 806
Query: 210 KERKKKEERKKERQKDRQTNWREKERGKRER 240
+E+ + +E K Q+++ EK G+ E+
Sbjct: 807 EEKMRGQEEKMRGQEEKMWGQEEKMWGQEEK 837
Score = 98.6 bits (244), Expect = 4e-21
Identities = 60/219 (27%), Positives = 137/219 (62%), Gaps = 16/219 (7%)
Query: 38 IREREREIETRKEGKKERES---ERKKERREREKRKREREK---ERKRERGKKEKKGERK 91
+RE+E +++ ++E +E+E E++++ +E+E++ E+E+ E++ + ++++ E+K
Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK 664
Query: 92 KEERERKKRRREKENKEGEEK----EKRKKKEKKERGRTSKEGKERERKEERKREE--RK 145
++ E +K + +++ +E EEK EK +KK +++ +T + K RE + R+RE+ R+
Sbjct: 665 EKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMRE 724
Query: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKE-RKKRERNRKERKKERERKE 204
E E +E+ EK +E++E+ + + +++ E+EE+ E+E K ++R +KE+ E E+ +
Sbjct: 725 EEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 784
Query: 205 RRER---KKERKKKEERKKERQKDRQTNWREKERGKRER 240
+E+ ++E+ + +E K Q+++ EK RG+ E+
Sbjct: 785 EQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEK 823
Score = 97.8 bits (242), Expect = 7e-21
Identities = 73/249 (29%), Positives = 146/249 (58%), Gaps = 36/249 (14%)
Query: 31 QPGWQSEIREREREIETRKEGKKERESERKKER-REREKRKREREKERKRERGKKEKKGE 89
Q W E R ++ E K+ + E R++ER REREK+ RE E+E RE+ +K ++ E
Sbjct: 558 QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE-EEEMMREQEEKMQEQE 616
Query: 90 RKKEERERKKRRREKENKEGEEK----------------EKRKKKEKKERGRTSKEGKER 133
K +E+E K +E++ +E EEK E+++ E+KE+ ++ +E+
Sbjct: 617 EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 676
Query: 134 ERKEERKRE--ERKERERKKEEREK-----ERERKERKKRER-KQVGEKEEERKEKERK- 184
E+ +E++ + E+++ E+K +E+EK E+ R+E RER K++ E+EE +E+E K
Sbjct: 677 EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKM 736
Query: 185 -ERKKRERNRKERKKERERK--ERRERKKERKKKEERKK-----ERQKDRQTNWREKERG 236
E++++ + ++E E+E K E+ E+ E+++ E+K+ E+ ++++ W ++E+
Sbjct: 737 QEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEK- 795
Query: 237 KRERKERKK 245
R+++E+ +
Sbjct: 796 MRDQEEKMR 804
Score = 96.7 bits (239), Expect = 2e-20
Identities = 71/258 (27%), Positives = 141/258 (54%), Gaps = 47/258 (18%)
Query: 35 QSEIREREREIETRKEGKKERES---------ERKKERREREKRKREREK---ERKRERG 82
+ +RE+E +++ ++E E+E E+K++ E+EK + + EK + ++ R
Sbjct: 463 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 522
Query: 83 KKEKKGERKKEERERKKRRREKENKEGEEK-----------EKRKKKEKKERGRTSKEGK 131
++E G+ KK R+ K R +E + E EEK E+R +K+ +E+ + + + +
Sbjct: 523 QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQE 582
Query: 132 ERERKEERKREE-----------RKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180
E+ R+EER RE R++ E+ +E+ EK +E++E+ + +++ E+EE+ E
Sbjct: 583 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWE 642
Query: 181 KERK----ERKKRERNR----KERKKERERKERRERKKERKKK----EERKKERQKDRQT 228
+E K E K E+ R KE+ E E+ + +E+ +E+++K E+ +K+ Q+ +
Sbjct: 643 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Query: 229 NW-REKERGKRERKERKK 245
W +EK R + +ER+K
Sbjct: 703 TWDQEKMREEESMREREK 720
Score = 95.5 bits (236), Expect = 4e-20
Identities = 59/225 (26%), Positives = 127/225 (56%), Gaps = 17/225 (7%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E + E+E K +++R E+K++ E EK + + + + + E+ +++K E+K +
Sbjct: 641 WEQEEKMWEQE---EKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQ 697
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK-------- 145
E+E+K +EK +E +E+ KK ++E +E K +E++E+ + +E +
Sbjct: 698 EQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKM 757
Query: 146 -ERERKKEEREKERERKER-----KKRERKQVGEKEEERKEKERKERKKRERNRKERKKE 199
E+E K E+++ E+KE+ K +E++++ E+EE+ +++E K R + E+ R + +K
Sbjct: 758 WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKM 817
Query: 200 RERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
R ++E+ ++E+ +E K Q+++ EK K + +E K
Sbjct: 818 RGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEK 862
Score = 94.0 bits (232), Expect = 1e-19
Identities = 61/252 (24%), Positives = 138/252 (54%), Gaps = 13/252 (5%)
Query: 6 SSRAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERRE 65
+ R +L E +S T + + E + ++ + K E + K+ +R+
Sbjct: 195 ADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRK 254
Query: 66 REKRK----------REREKERKRERGKKEKKGERKKEER--ERKKRRREKENKEGEEKE 113
E+ K + E R+ E ++++K RK+EE+ +++R RE+E K E++E
Sbjct: 255 LERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEE 314
Query: 114 KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGE 173
K ++EK+ R + KE +E+E++ ++E R++ E+ +E+ EK E++E+ + + +++
Sbjct: 315 KMWRQEKRLREQ-EKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWR 373
Query: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREK 233
+EE E+E++ R++ ++ R + ++ E+ ER K+ER +++E+ E+ + + + +
Sbjct: 374 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQ 433
Query: 234 ERGKRERKERKK 245
E+ K+ R + +K
Sbjct: 434 EQEKKTRDQEEK 445
Score = 91.7 bits (226), Expect = 5e-19
Identities = 65/217 (29%), Positives = 124/217 (57%), Gaps = 13/217 (5%)
Query: 35 QSEIREREREI-ETRKEGKKERESERK---KERREREKRKREREKERKRERGKKEKKGER 90
Q +++E+E +I E K KK +E E+K +E+ E+ REREK + RE + ++ E
Sbjct: 676 QEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREK-KMREEEEMMREQEE 734
Query: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK--ERE 148
K +E+E K + +E+E E EEK ++++ E+ R E KE+ + E+ +E+ K E+E
Sbjct: 735 KMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRL-PEQKEKLWEHEKMQEQEKIWEQE 793
Query: 149 RKKEEREKERERKERKKR--ERKQVGEKEEERKEKER---KERKKRERNRKERKKERERK 203
K ++E++ +E K R E K G++E+ ++E+ +E K + K +E + +
Sbjct: 794 EKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKME 853
Query: 204 ERRERKKERKKKEERKKERQKDRQTNWREKERGKRER 240
E+ + ++E+ +++E K Q+++ EK RG+ E+
Sbjct: 854 EKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 79.7 bits (195), Expect = 2e-15
Identities = 62/221 (28%), Positives = 122/221 (55%), Gaps = 16/221 (7%)
Query: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
E++ + TR + K +R E + R+ + R E KK + + K E
Sbjct: 180 ELQRALSAVSTRHK-KADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAE 238
Query: 97 RKKRRREKENKEGEEKEKRKK---------KEKKERGRTSKEGKERERKEERKREER--K 145
+K + KE + K +R K ++E R +E +E+E+K RK+EE+ +
Sbjct: 239 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKI-RKQEEKMWR 297
Query: 146 ERERKKEEREKERERKERKKRERKQVGEKEEE--RKEKERKERKK-RERNRKERKKERER 202
+ ER +E+ K RE++E+ R+ K++ E+E+E +EKE +E+K+ RE+ + +++E +
Sbjct: 298 QEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKM 357
Query: 203 KERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
E+ E+ +E+++K R++ER +++ RE+E+ R+++ER
Sbjct: 358 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398
Score = 60.1 bits (144), Expect = 2e-09
Identities = 41/177 (23%), Positives = 91/177 (51%), Gaps = 4/177 (2%)
Query: 73 REKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKE 132
R K+ R + K+ + E R E+ K+ E +++ + E+ KE
Sbjct: 191 RHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKE 250
Query: 133 RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERN 192
+RK ER + + + + E R+ +E +++E+K ++E+ +++ER ++ +
Sbjct: 251 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMR 310
Query: 193 RKERKKERERKERRERKKERKKKE----ERKKERQKDRQTNWREKERGKRERKERKK 245
+E K R+ K RE++KE +++E E+K+ R+++ Q +E++ ++E K R++
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQ 367
Score = 57.4 bits (137), Expect = 1e-08
Identities = 39/141 (27%), Positives = 82/141 (58%), Gaps = 7/141 (4%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKER---REREKRKREREKERKRE---RGKKEKK 87
W+ E + E+E + ++ + + E+ E +E+EK + EK R +E RG++EK
Sbjct: 751 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKM 810
Query: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147
++++ R ++++ +E K ++EK +E+K G+ K ++ + +EE+ RE+ +E+
Sbjct: 811 RGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQ-EEK 869
Query: 148 ERKKEEREKERERKERKKRER 168
R +EE+ +E+E K R + E+
Sbjct: 870 MRGQEEKMREQEEKMRGQEEK 890
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 115 bits (289), Expect = 3e-26
Identities = 83/263 (31%), Positives = 145/263 (55%), Gaps = 26/263 (9%)
Query: 8 RAAVKLNTELQM-VSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERRER 66
++ +K NT L+M CS + K + E E+ + E K R E K +RE
Sbjct: 517 KSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 576
Query: 67 EKRK----REREKERKRERGKK--------EKKGERKKEER--ERKKRRREKENKEGEEK 112
RK RER ++ K E+ K+ ++K E+ KEER E K +++ K E +
Sbjct: 577 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 636
Query: 113 EKRKKKEKKERGRTSKEGKERERKEE---RKREERKERERKK-------EEREKERERKE 162
+RK++E+ R R ++ +E R +E +K+EE +ER RK E+RE+ER +E
Sbjct: 637 ARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE 696
Query: 163 RKKRERKQVGEKEEERKEKERKERKKRERNRKER-KKERERKERRERKKERKKKEERKKE 221
R+++ER++ +E+ER+E+ER+ ++ R +ER + ERE +ER + + +K++ +R+ E
Sbjct: 697 RREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELE 756
Query: 222 RQKDRQTNWREKERGKRERKERK 244
+K ++ R ER +E +E+K
Sbjct: 757 EKKKKEEQQRLAERQLQEEQEKK 779
Score = 110 bits (276), Expect = 9e-25
Identities = 70/206 (33%), Positives = 127/206 (61%), Gaps = 12/206 (5%)
Query: 38 IREREREIETRKEGKKERESERKKERREREKRKRER---EKERKRERGKK--EKKGERKK 92
++ RER + ++E KK+ E + + + EK K ER EK +K+ KK E + RK+
Sbjct: 582 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 641
Query: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
EE R+ R ++E +E +E +KK+++E+ R K + + E+R++E R++ R++E
Sbjct: 642 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 701
Query: 153 EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE-RERKERRERKKE 211
RE+ER +ER+++ER Q+ E+E R++ ER + ER +ER+K R +KE+ +R+ E
Sbjct: 702 RREQERREQERREQER-QLAEQERRREQ----ERLQAERELQEREKALRLQKEQLQRELE 756
Query: 212 RKKKEERKKERQKDRQTNWREKERGK 237
KKK+E +++R +RQ ++++ K
Sbjct: 757 EKKKKE-EQQRLAERQLQEEQEKKAK 781
Score = 108 bits (271), Expect = 3e-24
Identities = 70/207 (33%), Positives = 132/207 (63%), Gaps = 22/207 (10%)
Query: 40 EREREIETRKEGKKERESERKKERRER--------EKRKRER---EKERKRERGKK--EK 86
ER R++ +E ++ + E+KK+ ++ EK K ER EK +K+ KK E
Sbjct: 576 ERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV 635
Query: 87 KGERKKEERERKKR--RREKENKEGEEKEKRKKKEKKERGRTSKEGKE--RERKEERKRE 142
+ RK+EE R+ R ++E+E + +E ++KK+E++ER R + E K +R++ER+ +
Sbjct: 636 EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 695
Query: 143 ERKERERKKEE-REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER----K 197
ER+E+ER+++E RE+ER +ER+ E+++ E+E + E+E +ER+K R +KE+
Sbjct: 696 ERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQREL 755
Query: 198 KERERKERRERKKERKKKEERKKERQK 224
+E+++KE ++R ER+ +EE++K+ ++
Sbjct: 756 EEKKKKEEQQRLAERQLQEEQEKKAKE 782
Score = 87.0 bits (214), Expect = 1e-17
Identities = 59/220 (26%), Positives = 126/220 (57%), Gaps = 19/220 (8%)
Query: 35 QSEIREREREIETRKE-GKKERESERKKERREREKR------KREREKERKRERGKKEKK 87
+ +I ++ +I+ + E K+ER +E K +++ K+ +R++E+E +R R ++++
Sbjct: 596 KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE 655
Query: 88 GERKKEERERKKRRREKENKEGEEKEKR----KKKEKKERGRTSKEGKERERKE--ERKR 141
ER+ +E +KK+ E+E + KR +++E++E+ R +E +E+ER+E R++
Sbjct: 656 EERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQ 715
Query: 142 EER---KERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK 198
E + +ER R++E + ERE +ER+K R Q KE+ ++E E K++K+ ++ ER+
Sbjct: 716 ERQLAEQERRREQERLQAERELQEREKALRLQ---KEQLQRELEEKKKKEEQQRLAERQL 772
Query: 199 ERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKR 238
+ E++++ + K + Q T+++ +G R
Sbjct: 773 QEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHR 812
Score = 29.3 bits (64), Expect = 3.3
Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 4/74 (5%)
Query: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEE----ERKEKERKERKKR 189
E +EE +R +E ++ E K +K R+K+ R + E R+ RK R +
Sbjct: 36 EIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQ 95
Query: 190 ERNRKERKKERERK 203
+R+ R K+ K
Sbjct: 96 LSSRRLRSKDSVEK 109
Score = 28.1 bits (61), Expect = 7.3
Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 34 WQSEIREREREIETRKEGKKERESERK--KERREREKRKREREKERKRERGKKEKKGERK 91
W EI+E + TR E KE E K ++ R+KR+ ++ R+ ++ +
Sbjct: 33 WLEEIQEEAERMFTR-EFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKS 91
Query: 92 KEERERKKRRREKENKE 108
+ + +R R K++ E
Sbjct: 92 RSSQLSSRRLRSKDSVE 108
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 115 bits (288), Expect = 3e-26
Identities = 56/130 (43%), Positives = 94/130 (72%), Gaps = 8/130 (6%)
Query: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEK-KERGRTSKEGKERERKEERKR 141
KK+KK +++ EE E + E+E KEG+ KEKRK+K K KE+ + +KE ++R+ KEE ++
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 142 EERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERE 201
+ +++R++KKEE E+E E +E ++ EKEEE KE+ R+ +KK++R RKE ++E++
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEE-------EKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113
Query: 202 RKERRERKKE 211
+K RR+ KK+
Sbjct: 114 KKRRRKTKKK 123
Score = 114 bits (284), Expect = 1e-25
Identities = 49/123 (39%), Positives = 92/123 (74%)
Query: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
+KK++++KE +E EE E+ +++E+KE R K ++R+ KE++K+ + E+ ++KEE EK
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216
+R+RK +KK+E ++ E+EEE +E++ +E K+ R RK++KK R ++E E+KK+R++K
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
Query: 217 ERK 219
++K
Sbjct: 121 KKK 123
Score = 105 bits (263), Expect = 3e-23
Identities = 51/134 (38%), Positives = 93/134 (69%), Gaps = 11/134 (8%)
Query: 112 KEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQV 171
K+K+KKK++ E ++E +E E KE +++E+RKE K++E+EK+++ KE +KR+ K+
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKE---KRKEKEKKKKTKETEKRKEKEE 57
Query: 172 GEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWR 231
EK+ +RK K++KE ++RE +E ++E+E +E+ E ++ +KKK+ R+KE +
Sbjct: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE-------- 109
Query: 232 EKERGKRERKERKK 245
E+++ KR RK +KK
Sbjct: 110 EEKKKKRRRKTKKK 123
Score = 105 bits (262), Expect = 4e-23
Identities = 60/142 (42%), Positives = 98/142 (69%), Gaps = 19/142 (13%)
Query: 48 RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENK 107
+K+ KK++E+E +E E E+ E EKE KR+ +KEK RK++E+++K + EK +
Sbjct: 1 KKKKKKKKETEETEETEETEE---EEEKEGKRKEKRKEK---RKEKEKKKKTKETEKRKE 54
Query: 108 EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRE 167
+ EE++KRK+K KK++ +E ER+EE EE +E E+++EE+E+ R RK++KKR
Sbjct: 55 KEEEEKKRKRKRKKKK-------EEEEREEE---EEEEEEEKEEEEKEEGRRRKKKKKRR 104
Query: 168 RKQVGEKEEERKEKERKERKKR 189
RK E+EEE+K+K R++ KK+
Sbjct: 105 RK---EEEEEKKKKRRRKTKKK 123
Score = 103 bits (258), Expect = 1e-22
Identities = 47/128 (36%), Positives = 92/128 (71%), Gaps = 6/128 (4%)
Query: 64 REREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKER 123
++++K+K+E E+ + E ++E++ E K++E+ ++KR+ +++ K+ +E EKRK+KE++E+
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 124 GRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKER 183
R K K++E +E + EE +E E+++EE+E+ R RK++KKR RK EE +EK++
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK------EEEEEKKK 114
Query: 184 KERKKRER 191
K R+K ++
Sbjct: 115 KRRRKTKK 122
Score = 97.8 bits (242), Expect = 7e-21
Identities = 44/130 (33%), Positives = 94/130 (72%), Gaps = 11/130 (8%)
Query: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGE----RKKEERER 97
+++ + +KE ++ E+E +E E+E +++E+ KE+++E+ KK+K E ++KEE E+
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 98 KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKE 157
K++R+ K+ KE EE+E+ +++E++E+ +E E++E R+R+++K+R RK+EE EK+
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEK-------EEEEKEEGRRRKKKKKRRRKEEEEEKK 113
Query: 158 RERKERKKRE 167
++R+ + K++
Sbjct: 114 KKRRRKTKKK 123
Score = 96.7 bits (239), Expect = 2e-20
Identities = 47/121 (38%), Positives = 85/121 (70%), Gaps = 6/121 (4%)
Query: 35 QSEIREREREIETRKEGKKE--RESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
+ E E E ET +E +KE R+ +RK++R+E+EK+K+ +E E+++E+ ++EKK +RK+
Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66
Query: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
+KK+ E+ +E EE+E+ K++E+KE GR K+ K+R RKEE + +++K R + K+
Sbjct: 67 ----KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Query: 153 E 153
+
Sbjct: 123 K 123
Score = 80.1 bits (196), Expect = 2e-15
Identities = 43/115 (37%), Positives = 78/115 (67%), Gaps = 11/115 (9%)
Query: 30 TQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGE 89
T+ + E +E +R+ E RKE +KE+E ++K + E+ K K E EK+RKR+R KK+++ E
Sbjct: 16 TEETEEEEEKEGKRK-EKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEE 74
Query: 90 RKKEERERKKRRREKENKEG----EEKEKRKKKEKKERGRTSKEGKERERKEERK 140
R++EE E ++ + E+E +EG ++K++R+K+E++E+ K+R RK ++K
Sbjct: 75 REEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK------KKKRRRKTKKK 123
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 114 bits (285), Expect = 8e-26
Identities = 57/212 (26%), Positives = 133/212 (62%), Gaps = 1/212 (0%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E + RE E E E +K RE E K++ E+ + + +R+++ + ++EK E++++
Sbjct: 340 WEKEEKIRELE-EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 398
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
RE+++ +E+E K GE++EK ++E++ + + K ++ E+ E++++ R++ E+ +E+
Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 458
Query: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
E +E++E+ + ++ E+E + +E+E K R++ E+ R++ KK RE++E+ ++E
Sbjct: 459 EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518
Query: 214 KKEERKKERQKDRQTNWREKERGKRERKERKK 245
+++E K Q+++ EK + + E+ R++
Sbjct: 519 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 550
Score = 109 bits (273), Expect = 2e-24
Identities = 65/219 (29%), Positives = 141/219 (64%), Gaps = 18/219 (8%)
Query: 35 QSEIREREREIETRKEGKKERESERKKER-----REREKRKREREKERKRERGKKEKKGE 89
Q +IRE+E E R+E +K RE E+++E+ R+ EK + + EK R++E +E+ E
Sbjct: 356 QEKIREQE---EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQ--E 410
Query: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
K E+E K +E+E +E EEK +R++++ +E+ + +E +E+ R++E +E++E+
Sbjct: 411 EKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMG 470
Query: 150 KK-----EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKE 204
++ E+ K +E++E+ +R+ +++ E+E++ +E+E K R++ E +++ +K E++E
Sbjct: 471 EQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 530
Query: 205 RRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
+ ++E+ +++E K RQ+++ RE+E R+++E+
Sbjct: 531 KMCEQEEKMQEQEEKMRRQEEKM---REQEVRLRQQEEK 566
Score = 108 bits (269), Expect = 6e-24
Identities = 63/256 (24%), Positives = 143/256 (55%), Gaps = 20/256 (7%)
Query: 8 RAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERRERE 67
RA + L + H+ K + + + E E+ R ++E + R++E+ +
Sbjct: 241 RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQER 300
Query: 68 KRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK---------EKRKKK 118
+ K + ++E+ RE+ +K ++ E E+E K RR+E+ E EEK E+ K +
Sbjct: 301 EEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 360
Query: 119 EKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEER 178
E++E+ + ++ +E+E+++E++ + ++ E+ +E+ EK RE++E + + +++GE+EE+
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Query: 179 KEKE-----------RKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQ 227
E+E R+E K RE+ +K R++E + +E+ E +E+++K ++ + +++
Sbjct: 421 WEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQE 480
Query: 228 TNWREKERGKRERKER 243
+E+E R ++E+
Sbjct: 481 AKMQEQEEKMRRQEEK 496
Score = 108 bits (269), Expect = 6e-24
Identities = 67/238 (28%), Positives = 143/238 (60%), Gaps = 6/238 (2%)
Query: 13 LNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERES---ERKKERREREKR 69
L ELQ VS ++ W +++E ++ ++E +ERE E++++ RE+E++
Sbjct: 258 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEK 317
Query: 70 KREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE-KEKRKKKEKKERGRTSK 128
R R++E E+ +K ++ E E+E K R E++ E E+ +E+ +K++++E+ R +
Sbjct: 318 MR-RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376
Query: 129 EGKERERKEERKREERKERERK-KEEREKERERKERKKRERKQVGEKEEERKEKERKERK 187
+ +E+E K R+ E+ +E+E K +E+ E +E++E+ + +++ E+EEE +E+E K R+
Sbjct: 377 KRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR 436
Query: 188 KRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+ E+ R++ KK RE++E+ ++E +++E K Q+ + K + + E+ R++
Sbjct: 437 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQE 494
Score = 102 bits (253), Expect = 4e-22
Identities = 59/188 (31%), Positives = 124/188 (65%), Gaps = 9/188 (4%)
Query: 34 WQSE--IREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERK 91
W+ E IRE+E +I ++E +E+E + ++ + +++ E +++ ++ R ++EK E++
Sbjct: 386 WRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQE 445
Query: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
K+ RE++++ RE+E E++EK ++E K +E K +E++E+ +R+E K RE++K
Sbjct: 446 KKIREQEEKIREQEEMMQEQEEKMGEQEGK---MCEQEAKMQEQEEKMRRQEEKIREQEK 502
Query: 152 EEREKE---RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
+ RE+E RE++E + + +++ E+EE+ E+E K +++ E+ R++ +K RE +E R R
Sbjct: 503 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE-QEVRLR 561
Query: 209 KKERKKKE 216
++E K +E
Sbjct: 562 QQEEKMQE 569
Score = 90.9 bits (224), Expect = 9e-19
Identities = 57/219 (26%), Positives = 121/219 (55%), Gaps = 8/219 (3%)
Query: 35 QSEIREREREIETRK----EGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90
Q ++E +R++E K + + + E++ + + K + + E + ++ E
Sbjct: 229 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 288
Query: 91 KKEERERKKRRREKENKEGEEK--EKRKKKEKKERGRTSKEGKERERKEERKREERKERE 148
K +E K + RE++ +E EEK E+ +K ++E KE K R ++E +E K RE
Sbjct: 289 KMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 348
Query: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
+++ E+E+ R++ +KR+ ++ ++E+R+E+E K ++ E+ R++ +K RE++E +
Sbjct: 349 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQE 408
Query: 209 KKERKKKEERKKERQKDRQTNWREKERGKRE--RKERKK 245
++E+ ++E K Q++ EK R + E R++ KK
Sbjct: 409 QEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKK 447
Score = 82.8 bits (203), Expect = 2e-16
Identities = 58/231 (25%), Positives = 130/231 (56%), Gaps = 23/231 (9%)
Query: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREK-------------ERKRERGK 83
E++E+ +++ + + + +SE + +E KRK ER K +E
Sbjct: 206 ELKEKNAKLQEKLQLVESEKSEIQLNVKEL-KRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 84 KEKKGERKKEERERKKR-RREKENKEGEEKEKRKKKEKK--ERGRTSKEGKERERKEERK 140
K + + EE E R +++E K ++EK +++E+K E+ +E +E+ R++E
Sbjct: 265 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEM 324
Query: 141 REERKERERKKEEREKERERK----ERKKRERKQVGEKEEERKEKE--RKERKKRERNRK 194
E++E+ R++EE E+E K E K E++++ E+EE+R+E+E R++ K++E+ K
Sbjct: 325 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384
Query: 195 ERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
++E + +E+ E+ +E+++ + ++E+ +++ E+E +E++E+ +
Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMR 435
Score = 67.8 bits (164), Expect = 8e-12
Identities = 54/229 (23%), Positives = 112/229 (48%), Gaps = 22/229 (9%)
Query: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
E+ + + T+K+ K +R E + R+ + R E +K K + K + E
Sbjct: 164 ELEQALSAVATQKK-KADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVE 222
Query: 97 RKKRRREKENKEGEEKEKRKK---KEKKERGRTSKEGKER-----------ERKEERKRE 142
+K + KE + K +R K +++ + GKE E E R
Sbjct: 223 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRL 282
Query: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERK-------EKERKERKKRERNRKE 195
+++ E+ + EK +ER+E+ + + +++ E+EE+ + EKE K R++ E ++
Sbjct: 283 NQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 342
Query: 196 RKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
+K RE +E+ +++ +++EE+++E +K R+ R+++ K R+E K
Sbjct: 343 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 391
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 112 bits (281), Expect = 2e-25
Identities = 60/217 (27%), Positives = 135/217 (62%), Gaps = 5/217 (2%)
Query: 34 WQSEIREREREIETRKEGKKERESERK----KERREREKRKREREKERKRERGKKEKKGE 89
W+ E + RE+E + R++ +K E K ++ RE EKR+ + E R+ E+ +++++
Sbjct: 480 WRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539
Query: 90 RKKEE-RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE 148
R+KE+ E++++ R++E K ++EK +E+K R + K ++ E+ E++ + R++ E
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599
Query: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
+ +E+ E +E++E+ + +++ E+EE+ +E+E K R++ E+ R++ KK RE++E+
Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 659
Query: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
++E +++E K Q+++ EK + + E+ R++
Sbjct: 660 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 696
Score = 111 bits (277), Expect = 7e-25
Identities = 68/229 (29%), Positives = 146/229 (63%), Gaps = 20/229 (8%)
Query: 34 WQSEIREREREIETRKEGK-KERESERKKERREREKRKR-EREKERKRERGKKEKKGERK 91
W+ E + RE E + ++ K +E+E +R++E + RE+ KR E+E + R+ K ++ E+
Sbjct: 434 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 493
Query: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER--KEERKREERKERER 149
+E+ E+ R+ EK +++ + +E+ K++E++E R ++ +E+E +++ K E++E+ R
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIR 553
Query: 150 KKEER------------EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERK 197
K+EE+ EK RE++E+ R+ +++ E+EE+ +E+E K R++ E +++ +
Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613
Query: 198 K--ERERK--ERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
K E+E K E+ E+ +E+++K R++E+ ++++ RE+E RE++E
Sbjct: 614 KMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Score = 109 bits (273), Expect = 2e-24
Identities = 61/218 (27%), Positives = 137/218 (62%), Gaps = 9/218 (4%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E + E+E +E ++E+E ++E + RE+ + R+KE+ E+ +K +K E K
Sbjct: 501 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW 560
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER-----E 148
+E K +E++ +E EEK R++++ +E+ +E +E+ R++E +E++E+ E
Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620
Query: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK--ERERK--E 204
+ E+ EK +E++E+ +R+ +++ E+E++ +E+E K R++ E +++ +K E+E K E
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 680
Query: 205 RRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
+ E+ +E+++K R++E+ +++ R++E +E +E
Sbjct: 681 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 108 bits (271), Expect = 3e-24
Identities = 71/248 (28%), Positives = 144/248 (58%), Gaps = 16/248 (6%)
Query: 8 RAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKER---- 63
RA + L + H+ K + + + E E+ R ++E + R++E+
Sbjct: 314 RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW 373
Query: 64 ----REREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKE 119
+E+E++ RE+E E+ RE+ +K ++ E E+E K RR+E+ E EEK +R+++
Sbjct: 374 EEKIQEQEEKIREQE-EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 432
Query: 120 KKERGRTSKEGKERERKEERKREER-KERERKKEEREKERERKERKKRERKQVGEKEEER 178
E KE K RE +E+ +E+ +E+E K++E EK RE+++R+++E K ++E+ R
Sbjct: 433 MWE-----KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 487
Query: 179 KEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKER-GK 237
+++E+ ++ + R+E K + K R E K++ +++ R++E+ ++++ WR+KE+ +
Sbjct: 488 EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHE 547
Query: 238 RERKERKK 245
+E K RK+
Sbjct: 548 QEEKIRKQ 555
Score = 108 bits (271), Expect = 3e-24
Identities = 60/218 (27%), Positives = 142/218 (65%), Gaps = 12/218 (5%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ +I+E+E +I ++E +E+E +K RR+ E + EK R++E EK+ + +++
Sbjct: 373 WEEKIQEQEEKIREQEEKIREQE---EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 429
Query: 94 ER---ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
E E++++ RE E K E+++ R+++EK++ ++ +E+E+++E++ + ++ E+
Sbjct: 430 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE---EEKIREQEKRQEQEAKMWRQEEKI 486
Query: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERE---RKERRE 207
+E+ EK RE++E+ R+ +++ E+E+ R+E++R+E+++ R ++ +++ E +KE+
Sbjct: 487 REQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIH 546
Query: 208 RKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
++E+ +K+E K RQ+++ + EK R + E+ R++
Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQE 584
Score = 108 bits (271), Expect = 3e-24
Identities = 62/221 (28%), Positives = 136/221 (61%), Gaps = 9/221 (4%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKER----REREKRKREREKERKRERGKKEKKGE 89
W+ E + R +E ++ +K RE E K RE+E++++E EK R++E+ ++++
Sbjct: 420 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 479
Query: 90 RKKEE--RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER--- 144
++EE RE++++ RE+E K ++EK ++EK +E +E R+EE+ RE+
Sbjct: 480 WRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539
Query: 145 KERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKE 204
+++E+ E+ EK R+++E+ R+ +++ ++EE+ +E+E K ++ E+ R++ +K RE++E
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599
Query: 205 RRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+ ++E +++E K Q+++ EK + + E+ R++
Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQE 640
Score = 107 bits (268), Expect = 7e-24
Identities = 69/232 (29%), Positives = 133/232 (57%), Gaps = 29/232 (12%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKRE---------REKERKRERGKKE 85
Q E R+ E+ KE K R+ E E+ E+ +R+ E RE E K +K
Sbjct: 394 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 453
Query: 86 KKGERKKEERER---KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142
++ E K++E E+ +++R+E+E K ++EK +++E+K R + K R+EE+ E
Sbjct: 454 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW----RQEEKIHE 509
Query: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRER---------NR 193
+ K RE +K + ++E R+E K RE++++ ++E+ E+E K RK+ E+ ++
Sbjct: 510 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQ 569
Query: 194 KERKKERE----RKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERK 241
+E+ +E+E R+E + R++E K +E+ +K R+++ T +E++ G++E K
Sbjct: 570 EEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 621
Score = 86.7 bits (213), Expect = 2e-17
Identities = 54/220 (24%), Positives = 129/220 (58%), Gaps = 14/220 (6%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Q ++E +R++E K +++ + + + +E + + + + E + + R ++
Sbjct: 302 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE---ENELWNRLNQQ 358
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
+E K R+E++ +E EEK + ++++ +E+ +E +E+ R++E E++E+ R++EE
Sbjct: 359 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 418
Query: 155 EKERERKERKKRERKQVGEKEE-----ERKEKERKERKKRERNRKERKKERERKERRERK 209
E+E K R++ E + EKEE E K E+++ +++E R+E +K RE+++R+E++
Sbjct: 419 MWEKEEKMRRQEE--MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 476
Query: 210 KERKKKEERKKERQ----KDRQTNWREKERGKRERKERKK 245
+ ++EE+ +E++ + + WR++E+ + K R++
Sbjct: 477 AKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREE 516
Score = 78.2 bits (191), Expect = 6e-15
Identities = 53/211 (25%), Positives = 117/211 (55%), Gaps = 16/211 (7%)
Query: 46 ETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKE 105
E +++ K +E + E + E + +E +RK ER K ++ + E + KE
Sbjct: 279 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG----KE 334
Query: 106 NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKE-----RER 160
+ K + + +E + R +++ +E+ ++E K +E +E+ +++EE+ +E RE+
Sbjct: 335 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 394
Query: 161 KERKKRERKQVGEKEEERK-------EKERKERKKRERNRKERKKERERKERRERKKERK 213
+E+ +R+ + + EKEE+ + EKE K R++ E ++ +K RE +E+ +++ +
Sbjct: 395 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 454
Query: 214 KKEERKKERQKDRQTNWREKERGKRERKERK 244
++EE+++E +K R+ R+++ K R+E K
Sbjct: 455 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 485
Score = 60.5 bits (145), Expect = 1e-09
Identities = 49/227 (21%), Positives = 111/227 (48%), Gaps = 19/227 (8%)
Query: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
E+ + + T+K+ K +R E + R+ + R E +K K + K + E
Sbjct: 237 ELEQALSAVATQKK-KADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVE 295
Query: 97 RKKRRREKENKEGEEKEKRKK---KEKKERGRTSKEGKER-----------ERKEERKRE 142
+K + KE + K +R K +++ + GKE E E R
Sbjct: 296 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRL 355
Query: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
+++ E+ + EK +E +E+ + + +++ E+EE+ +E+E K R++ E ++ +K R +
Sbjct: 356 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 415
Query: 203 KERRERKKERKKKEE----RKKERQKDRQTNWREKERGKRERKERKK 245
+E K+E+ +++E K+E+ ++ + E+E+ + + ++R++
Sbjct: 416 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 462
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 112 bits (280), Expect = 3e-25
Identities = 82/266 (30%), Positives = 146/266 (54%), Gaps = 36/266 (13%)
Query: 8 RAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKE----R 63
++ +K NT L+M P + + E R+ E E + K E + R+ E +
Sbjct: 517 KSFIKRNTPLRM-------DPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLK 569
Query: 64 REREKRK----REREKERKRERGKK--------EKKGERKKEER--ERKKRRREKENKEG 109
RE RK RER ++ K E+ K+ ++K E+ KEER E K +++ K
Sbjct: 570 REERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME 629
Query: 110 EEKEKRKKKEKKERGRTSKEGKERERKEE---RKREERKERERK-------KEEREKERE 159
E + +RK++E+ R R ++ +E R +E +K+EE +ER RK E+RE+ER
Sbjct: 630 EVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 689
Query: 160 RKERKKRERKQVGEKEEERKEKERKERKKRERNRKER-KKERERKERRERKKERKKKEER 218
+ER+++ER++ +E+ER+E+ER+ ++ R +ER + ERE +ER + + +K++ +R
Sbjct: 690 EQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQR 749
Query: 219 KKERQKDRQTNWREKERGKRERKERK 244
+ E +K ++ R ER +E +E+K
Sbjct: 750 ELEEKKKKEEQQRLAERQLQEEQEKK 775
Score = 111 bits (277), Expect = 7e-25
Identities = 71/228 (31%), Positives = 136/228 (59%), Gaps = 23/228 (10%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKK--------EKKGER 90
+E+ER+ K+E E R+++ E ++R+ E K ++ ER +K E+ E
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
Query: 91 KKEERERK------KRRREKENKEGEEKEKRK----KKEKKERGRTSKEGKERERKEERK 140
KK++ E+K K + KE + EEK K+K K E+ E R +E R R +++
Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 650
Query: 141 REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER 200
EER+ +E ++++E+E+ER + ++ ++E+ER+E+ER+E+++RE+ R+E +ER
Sbjct: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERRE--QER 708
Query: 201 ERKERRERKKERKKKEER---KKERQKDRQTNWREKERGKRERKERKK 245
+ER+ ++ER++++ER ++E Q+ + +KE+ +RE +E+KK
Sbjct: 709 REQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKK 756
Score = 110 bits (276), Expect = 9e-25
Identities = 70/206 (33%), Positives = 127/206 (61%), Gaps = 12/206 (5%)
Query: 38 IREREREIETRKEGKKERESERKKERREREKRKRER---EKERKRERGKK--EKKGERKK 92
++ RER + ++E KK+ E + + + EK K ER EK +K+ KK E + RK+
Sbjct: 578 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 637
Query: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
EE R+ R ++E +E +E +KK+++E+ R K + + E+R++E R++ R++E
Sbjct: 638 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE 697
Query: 153 EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE-RERKERRERKKE 211
RE+ER +ER+++ER Q+ E+E R++ ER + ER +ER+K R +KE+ +R+ E
Sbjct: 698 RREQERREQERREQER-QLAEQERRREQ----ERLQAERELQEREKALRLQKEQLQRELE 752
Query: 212 RKKKEERKKERQKDRQTNWREKERGK 237
KKK+E +++R +RQ ++++ K
Sbjct: 753 EKKKKE-EQQRLAERQLQEEQEKKAK 777
Score = 108 bits (271), Expect = 3e-24
Identities = 70/207 (33%), Positives = 132/207 (63%), Gaps = 22/207 (10%)
Query: 40 EREREIETRKEGKKERESERKKERRER--------EKRKRER---EKERKRERGKK--EK 86
ER R++ +E ++ + E+KK+ ++ EK K ER EK +K+ KK E
Sbjct: 572 ERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEV 631
Query: 87 KGERKKEERERKKR--RREKENKEGEEKEKRKKKEKKERGRTSKEGKE--RERKEERKRE 142
+ RK+EE R+ R ++E+E + +E ++KK+E++ER R + E K +R++ER+ +
Sbjct: 632 EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 691
Query: 143 ERKERERKKEE-REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER----K 197
ER+E+ER+++E RE+ER +ER+ E+++ E+E + E+E +ER+K R +KE+
Sbjct: 692 ERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQREL 751
Query: 198 KERERKERRERKKERKKKEERKKERQK 224
+E+++KE ++R ER+ +EE++K+ ++
Sbjct: 752 EEKKKKEEQQRLAERQLQEEQEKKAKE 778
Score = 99.4 bits (246), Expect = 3e-21
Identities = 64/218 (29%), Positives = 126/218 (57%), Gaps = 26/218 (11%)
Query: 54 ERESERKKERREREKRK----REREKERKRERGKKEKKGERKKEERERKKRRREKENKEG 109
+R + + + +E+E+++ R +E+ + R K E+ R+ EE + K+ R ++ +
Sbjct: 521 KRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQA 580
Query: 110 EEKEKRKKKEKK-----------ERGRTSKEGKERERKEERKREERKERE---RKKEERE 155
E+ ++ K+EKK E+ +KE + E K ++K +K E R+K+E E
Sbjct: 581 RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 640
Query: 156 KER----ERKERKKRERKQVGEKEEERKEKERK--ERKKRERNRKERKKERERKERRERK 209
R +++E ++R ++ + +K+EE +E+ RK E K+ R++ ++E+ER+E+ R+
Sbjct: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
Query: 210 KERKKKEERKKERQKDRQTNWREKER--GKRERKERKK 245
+ER+++E R++ERQ Q RE+ER +RE +ER+K
Sbjct: 701 QERREQERREQERQLAEQERRREQERLQAERELQEREK 738
Score = 87.0 bits (214), Expect = 1e-17
Identities = 59/220 (26%), Positives = 126/220 (57%), Gaps = 19/220 (8%)
Query: 35 QSEIREREREIETRKE-GKKERESERKKERREREKR------KREREKERKRERGKKEKK 87
+ +I ++ +I+ + E K+ER +E K +++ K+ +R++E+E +R R ++++
Sbjct: 592 KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE 651
Query: 88 GERKKEERERKKRRREKENKEGEEKEKR----KKKEKKERGRTSKEGKERERKE--ERKR 141
ER+ +E +KK+ E+E + KR +++E++E+ R +E +E+ER+E R++
Sbjct: 652 EERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQ 711
Query: 142 EER---KERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK 198
E + +ER R++E + ERE +ER+K R Q KE+ ++E E K++K+ ++ ER+
Sbjct: 712 ERQLAEQERRREQERLQAERELQEREKALRLQ---KEQLQRELEEKKKKEEQQRLAERQL 768
Query: 199 ERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKR 238
+ E++++ + K + Q T+++ +G R
Sbjct: 769 QEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHR 808
Score = 29.3 bits (64), Expect = 3.3
Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 4/74 (5%)
Query: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEE----ERKEKERKERKKR 189
E +EE +R +E ++ E K +K R+K+ R + E R+ RK R +
Sbjct: 36 EIQEEAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQ 95
Query: 190 ERNRKERKKERERK 203
+R+ R K+ K
Sbjct: 96 LSSRRLRSKDSVEK 109
Score = 28.1 bits (61), Expect = 7.3
Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 34 WQSEIREREREIETRKEGKKERESERK--KERREREKRKREREKERKRERGKKEKKGERK 91
W EI+E + TR E KE E K ++ R+KR+ ++ R+ ++ +
Sbjct: 33 WLEEIQEEAERMFTR-EFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKS 91
Query: 92 KEERERKKRRREKENKE 108
+ + +R R K++ E
Sbjct: 92 RSSQLSSRRLRSKDSVE 108
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 112 bits (279), Expect = 4e-25
Identities = 63/221 (28%), Positives = 122/221 (55%), Gaps = 21/221 (9%)
Query: 28 PCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKK 87
P QP +RE+E R++ ERE E ++ R R +R+ +R+K R+ R + +
Sbjct: 1123 PPVQPPQHPRAEQREQERAVREQWA-EREREMERRERTRSEREWDRDKVREGPRSRSRSR 1181
Query: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTS---------------KEGKE 132
R+KE + K+++ EK+ K EE + + + + + KE +
Sbjct: 1182 DRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAER 1241
Query: 133 RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERN 192
ER +ER++ +++ E +++EREKE ER+ ++ ER+ ++ E +E++R+ ++RER+
Sbjct: 1242 AERAKEREKRRKEQEEEEQKEREKEAERERNRQLERE---KRREHSRERDRERERERERD 1298
Query: 193 RKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREK 233
R +R ++RER RER +ER +++ ++ R + R T R++
Sbjct: 1299 RGDRDRDRERD--RERGRERDRRDTKRHSRSRSRSTPVRDR 1337
Score = 73.6 bits (179), Expect = 2e-13
Identities = 56/214 (26%), Positives = 92/214 (42%), Gaps = 12/214 (5%)
Query: 32 PGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRE-RGKKEKKGER 90
P +QS + E E+ K SE K + + + RK ER R R+ R K +G +
Sbjct: 185 PDFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQ 244
Query: 91 KKEERE-----------RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEER 139
EE E R R + E +E EE+E+ + E++E ++ +E +E
Sbjct: 245 PAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEF 304
Query: 140 KREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE 199
K E + K EE ER + +++E + G + +E+ RK R++ KE K
Sbjct: 305 KEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTT 364
Query: 200 RERKERRERKKERKKKEERKKERQKDRQTNWREK 233
+E K + +E+ K R T R+K
Sbjct: 365 SPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKK 398
Score = 58.5 bits (140), Expect = 5e-09
Identities = 54/216 (25%), Positives = 91/216 (42%), Gaps = 25/216 (11%)
Query: 45 IETRKEGKKERESERKKERREREKRKREREKERKRERG-----KKEKKGERKKEERERKK 99
+E ++E ++R +E E E+ E E E G + + ++ E E +
Sbjct: 141 LEKQQELLRQRLEREAREAAELEEASAESEDEMIHPEGVASLLPPDFQSSLERPELELSR 200
Query: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER-----ERKKEER 154
K + EEK EK +G ER+ R R+ R + + +EE
Sbjct: 201 HSPRKSSSISEEKGD-SDDEKPRKG---------ERRSSRVRQARAAKLSEGSQPAEEEE 250
Query: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKE--- 211
++E + + R + + +EEE +E+E +E + E E +K RE +E K+E
Sbjct: 251 DQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEE 310
Query: 212 --RKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
R K EE ER K R ERG R + +++
Sbjct: 311 IPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEE 346
Score = 52.0 bits (123), Expect = 5e-07
Identities = 38/167 (22%), Positives = 71/167 (42%), Gaps = 42/167 (25%)
Query: 119 EKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEER 178
++ +T ++G R + + + E+RE+ER +E+ +++ +E R
Sbjct: 1101 DRPSETKTEEQGIPRPLHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERTR 1160
Query: 179 KEKE----------RKERKKRERNRKERKKERERKERRERKKERK--------------- 213
E+E R + R+R RKER K +E+K ++ K + +
Sbjct: 1161 SEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKA 1220
Query: 214 ---------------KKEERKKERQKDRQTNWREKERGKRERKERKK 245
+KE + ER K+R+ R KE+ + E+KER+K
Sbjct: 1221 APCIYWLPLTDSQIVQKEAERAERAKEREK--RRKEQEEEEQKEREK 1265
Score = 47.8 bits (112), Expect = 9e-06
Identities = 38/157 (24%), Positives = 70/157 (44%), Gaps = 3/157 (1%)
Query: 30 TQPGWQSEIRER-EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKG 88
+QP + E +E R + R + + E E ++E E E+ E E + + ++ ++
Sbjct: 243 SQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEE-EEEEEDDEEEEGDDEGQKSREAPIL 301
Query: 89 ERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER-KER 147
+ KEE E R + +E + K + +++E ERG +E RK R+++ KE
Sbjct: 302 KEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEM 361
Query: 148 ERKKEEREKERERKERKKRERKQVGEKEEERKEKERK 184
+ E+ERE K + + K E +K
Sbjct: 362 KTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKK 398
Score = 42.7 bits (99), Expect = 3e-04
Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 19/167 (11%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERRER---------EKRKREREKERKRERGKKE 85
+ E E + E E EG+K RE+ KE +E E+ ER K R +E+ E
Sbjct: 276 EEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLE 335
Query: 86 KKGERKKEERERKK-----RRREKENK-----EGEEKEKRKKKEKKERGRTSKEGKERER 135
+ G + + E +K +++EKE K E EE+E + + KE+ ++ + E
Sbjct: 336 RGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTED 395
Query: 136 KEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKE 182
+++ E+ +EE KE EEE + E
Sbjct: 396 RKKASLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPME 442
Score = 41.6 bits (96), Expect = 6e-04
Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 4/66 (6%)
Query: 40 EREREIETRKEGKKERESERKKERREREK---RKREREKERKRERGKKEKKG-ERKKEER 95
ERE+ E +E +ERE ER+++R +R++ R RER +ER R K+ + R R
Sbjct: 1276 EREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVR 1335
Query: 96 ERKKRR 101
+R RR
Sbjct: 1336 DRGGRR 1341
Score = 41.2 bits (95), Expect = 8e-04
Identities = 33/148 (22%), Positives = 67/148 (45%), Gaps = 2/148 (1%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
++E E E E E + ++E + E +K RE K +E+ + R K E+ + + +
Sbjct: 268 KTEEEEEEEEEEEEDDEEEEGDDEGQKS-REAPILKEFKEEGEEIPRVKPEEMMDERPKT 326
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
R +++ E+ + +E+ +K R + KE K EE +RE + + K++ +
Sbjct: 327 RSQEQEVLERGGRFTRSQEEARKSH-LARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSK 385
Query: 155 EKERERKERKKRERKQVGEKEEERKEKE 182
R +++ V E+ E+E
Sbjct: 386 SPSPPRLTEDRKKASLVALPEQTASEEE 413
Score = 37.7 bits (86), Expect = 0.009
Identities = 23/54 (42%), Positives = 34/54 (62%), Gaps = 3/54 (5%)
Query: 39 REREREIETRKEGKKERESERKKER-REREKRKRER-EKERKRERGKKEKKGER 90
RERERE E R G ++R+ ER +ER RER++R +R + R R +++ G R
Sbjct: 1289 RERERERE-RDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 110 bits (276), Expect = 9e-25
Identities = 73/257 (28%), Positives = 145/257 (56%), Gaps = 20/257 (7%)
Query: 8 RAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKER---- 63
RA + L + H+ K + + + E E+ R ++E + R++E+
Sbjct: 253 RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW 312
Query: 64 ----REREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK------- 112
+E+E++ RE+E E+ RE+ +K ++ E E+E K RR+E+ E EEK
Sbjct: 313 EEKIQEQEEKIREQE-EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 371
Query: 113 --EKRKKKEKKERGRTSKEGKERERKEERKREER-KERERKKEEREKERERKERKKRERK 169
EK +K ++E KE K RE +E+ +E+ +E+E K++E EK RE+++R+++E K
Sbjct: 372 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 431
Query: 170 QVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTN 229
++E+ R+++E+ ++++ R+E K + K R E K++ +++ R++E+ +++
Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491
Query: 230 WREKER-GKRERKERKK 245
WR+KE+ ++E K RK+
Sbjct: 492 WRQKEKMHEQEEKIRKQ 508
Score = 109 bits (272), Expect = 2e-24
Identities = 66/228 (28%), Positives = 142/228 (62%), Gaps = 18/228 (7%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRER-GKKEKKGERKK 92
W+ +I+E+E +I R++ +K RE E K R+E ++E + R+ E +KE+K R++
Sbjct: 312 WEEKIQEQEEKI--REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 369
Query: 93 E---ERERKKRRREKENKEGEEK---------EKRKKKEKKERGRTSKEGKERERKEERK 140
E E+E K RR+E+ E EEK E+ K +E++E+ + ++ +E+E+++E++
Sbjct: 370 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 429
Query: 141 REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER 200
+ ++ E+ +E+ EK RE++++ R+ +++ E+E+ R+E++R+E+++ R ++ ++
Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE 489
Query: 201 E---RKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
E +KE+ ++E+ +K+E K RQ+++ EK R + E+ R++
Sbjct: 490 EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQE 537
Score = 108 bits (271), Expect = 3e-24
Identities = 76/236 (32%), Positives = 150/236 (63%), Gaps = 31/236 (13%)
Query: 35 QSEIREREREIETRKEGKKERESERKKER-----------REREKRKREREKERKRERGK 83
Q +IRE+E E R+E +K RE E+++E+ RE+E++ RE+EK+ R+ K
Sbjct: 403 QEKIREQE---EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 459
Query: 84 ---KEK-KGERKKEERERKKRRREKENKEGE---EKEKRKKKEKKERGRTSKEGKERE-- 134
+EK + E K++E+E R+ EK +++ E +KEK ++E+K R + K ++ E
Sbjct: 460 IHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKI 519
Query: 135 RKEERKREERKERERKKEEREKERE---RKERKKRERKQVGEKEEERKEKE----RKERK 187
R++E K E++E+ ++EE+ +E+E R+E K E++++ E EE+R+E+E R+E K
Sbjct: 520 REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE-EEKRQEQEDKMWRQEEK 578
Query: 188 KRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
RE+ K ++E + +E+ E+++E+++K +++E+ ++++ +E+E RE++E+
Sbjct: 579 IREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
Score = 108 bits (271), Expect = 3e-24
Identities = 68/232 (29%), Positives = 140/232 (60%), Gaps = 25/232 (10%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E + E+E +E ++E+E ++E + E+ + R+KE+ E+ +K +K E K
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW 513
Query: 94 ERERKKRRREKENKEGEEK---EKRKKKEKKERGRTSKEGKERERK-EERKREERKERER 149
+E K R +E++ +E EEK ++ K +E++E R ++ E+E+ EE KR+E++++
Sbjct: 514 RQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW 573
Query: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKK--ERERKERRE 207
++EE K RE++E+ R+ +++ E+EE+R+E+E K K+ E+ R++ +K E+E K R +
Sbjct: 574 RQEE--KIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ 631
Query: 208 RKKERKKKE-----------------ERKKERQKDRQTNWREKERGKRERKE 242
+K R+++E E++++ Q+ +T WR++E+ + + K+
Sbjct: 632 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKK 683
Score = 108 bits (271), Expect = 3e-24
Identities = 62/222 (27%), Positives = 137/222 (61%), Gaps = 14/222 (6%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E + RE+E + R++ +K E K RE+E+ RE EK ++E+ +E+K + +++
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKI--REQEEMWREEEKMHEQEKIWEEEKRQEQED 570
Query: 94 ERERKKRR-REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
+ R++ + RE+E K ++EK +++E+K + + K K+ E+ E++ + +++ E+ +E
Sbjct: 571 KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIRE 630
Query: 153 EREKERERKERKKRERKQVGEKEEERKEKE-----------RKERKKRERNRKERKKERE 201
+ EK RE++E + + +++GE+EE+ E+E R+E K RE+ +K R++E +
Sbjct: 631 QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK 690
Query: 202 RKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
+E+ E +E+++K ++E+ +++ +E+E R ++E+
Sbjct: 691 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732
Score = 108 bits (270), Expect = 4e-24
Identities = 65/221 (29%), Positives = 132/221 (59%), Gaps = 20/221 (9%)
Query: 34 WQSEIR-EREREIETRKEGKKERESERKKERREREKRKRE---------REKERKRERGK 83
W+ E + R+ E+ KE K R+ E E+ E+ +R+ E RE E K +
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 404
Query: 84 KEKKGERKKEERER---KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK 140
K ++ E K++E E+ +++R+E+E K ++EK +++E+K R ++ K+ R+EE+
Sbjct: 405 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR----EQEKKMWRQEEKI 460
Query: 141 REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER 200
E+ K RE +K + ++E R+E K E++++ ++E+ E+E K RK+ E+ ++ +K R
Sbjct: 461 HEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIR 520
Query: 201 ERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERK 241
E++ E+ +E+++K R++E+ ++++ WRE+E+ + K
Sbjct: 521 EQE---EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
Score = 108 bits (270), Expect = 4e-24
Identities = 70/230 (30%), Positives = 144/230 (62%), Gaps = 23/230 (10%)
Query: 34 WQSEIR-EREREIETRKEGKKERES----ERKKERREREKRKREREKERKRERGKKEKKG 88
W+ E + R+ E+ KE K R+ E++++ RE E++ E+EK R++E ++E++
Sbjct: 359 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 418
Query: 89 ERKKEER-ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147
R++E+R E++ + +E K E++EK +++EKK + K ++ + +EE KR+E++E
Sbjct: 419 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEM 478
Query: 148 ERKKE----------EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERK 197
R++E ++EK E++E+ +++ ++V +EE+ +E+E K R++ E+ ++ +
Sbjct: 479 WRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEE 538
Query: 198 KERERKE--RRERKKERKKK--EERKKERQKDRQTNWREKERGKRERKER 243
K RE++E R E K ++K EE K++ Q+D+ WR++E+ RE++E+
Sbjct: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM--WRQEEK-IREQEEK 585
Score = 108 bits (269), Expect = 6e-24
Identities = 71/224 (31%), Positives = 142/224 (63%), Gaps = 17/224 (7%)
Query: 34 WQSEIREREREIETRKEGKKERESERK----KERREREKRKREREKERKRERGKKEKKGE 89
W+ E + RE+E + R++ KK E K ++ RE EKR+ + E R+ E+ ++++
Sbjct: 433 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIW 492
Query: 90 RKKEE-RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER---KEERKREERK 145
R+KE+ E++++ R++E K ++EK +++E+K R + K ++ E+ +EE REE K
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Query: 146 ERERKK---EEREKERE----RKERKKRERKQ-VGEKEEERKEKERKERKKRERNRKERK 197
E++K EE+ +E+E R+E K RE+++ V +EE+ +E+E K +++ E+ K+ +
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612
Query: 198 KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERK 241
K RE++E+ + ++E K +E+ +K R+++ T +E++ G++E K
Sbjct: 613 KIREQEEKIQ-EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Score = 105 bits (263), Expect = 3e-23
Identities = 63/230 (27%), Positives = 142/230 (61%), Gaps = 18/230 (7%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKER----REREKRKREREKERKRERGKKEKKGE 89
W+ E + R +E ++ +K RE E K RE+E++++E EK R++E+ ++++
Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 432
Query: 90 RKKEE--RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER--- 144
++EE RE++++ RE+E K ++EK ++EK +E +E R+EE+ E+
Sbjct: 433 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIW 492
Query: 145 KERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKE 204
+++E+ E+ EK R+++E+ R+ +++ E+EE+ +E+E K ++ E+ R++ + RE ++
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Query: 205 RRERKK----ERKKKEERKKERQKDR-----QTNWREKERGKRERKERKK 245
E++K E+++++E K RQ+++ + WR++E+ + + ++R++
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQE 602
Score = 105 bits (263), Expect = 3e-23
Identities = 73/239 (30%), Positives = 150/239 (62%), Gaps = 27/239 (11%)
Query: 34 WQSEIRERERE--------IETRKEGKKERESERKKERREREKRKREREKERKRERGKKE 85
W+ E + RE E I ++E ++E E R++E+R+ ++ K R++E+ RE+ +K
Sbjct: 387 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 446
Query: 86 KKGERK---KEER--ERKKRRREKENKEGEE--KEKRKKKEKKERGRTSK---EGKERER 135
++ E+K +EE+ E++K R E++ +E EE +++ K E++E R + E +E+ R
Sbjct: 447 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIR 506
Query: 136 KEERK--REERKERERKKEEREKERE--RKERKKRERKQVGEKEEERKEKER--KERKKR 189
K+E K R+E K RE++++ RE+E + R+E K RE++++ +EE+ E+E+ +E K++
Sbjct: 507 KQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ 566
Query: 190 ERNRK---ERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
E+ K + +K RE++E+ R++E+ +++E K++ Q+++ EK R + E+ + ++
Sbjct: 567 EQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE 625
Score = 105 bits (262), Expect = 4e-23
Identities = 59/218 (27%), Positives = 137/218 (62%), Gaps = 8/218 (3%)
Query: 34 WQSEIREREREIETRKEGKK-ERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
W+ E + RE+E R+E K E+E ++E+R+ ++ K R++E+ RE+ +K + E K
Sbjct: 534 WRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKI 593
Query: 93 EERERKKRRRE-----KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147
E+E K++ +E +E K E++EK +++E+K R + K ++ E +E++ + ++
Sbjct: 594 REQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE 653
Query: 148 ERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207
E+ E+ EK +E++E R+ +++ E+E++ +E+E K R++ E +++ +K E++E+
Sbjct: 654 EKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 713
Query: 208 RKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
++E+ +++E K RQ+++ W ++ R +++ ++ ++
Sbjct: 714 EQEEKMQEQEEKMRRQEEKM--WEQEVRLRQQEEKMQE 749
Score = 104 bits (259), Expect = 8e-23
Identities = 59/218 (27%), Positives = 143/218 (65%), Gaps = 9/218 (4%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E + E+E R++ K + E+ +++ E+ R+ E+ +E++ + ++E+K R++E
Sbjct: 479 WRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEE 538
Query: 94 E-RERKKRRREKENKEGEEK---EKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
+ RE+++ RE+E +EK E+++++++ + R ++ +E+E K R+ E+ +E+E
Sbjct: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598
Query: 150 KKEEREKERERKERKKRERKQ-VGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
K++E+E++ ++E K RE+++ + E+EE+ +E+E K R++ E +++ +K E++E+
Sbjct: 599 KRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 658
Query: 209 KKERKKKEE----RKKERQKDRQTNWREKERGKRERKE 242
++E+ +++E R++E+ ++++ RE+E RE++E
Sbjct: 659 QEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Score = 103 bits (258), Expect = 1e-22
Identities = 57/216 (26%), Positives = 135/216 (62%), Gaps = 9/216 (4%)
Query: 34 WQSEIREREREIETRKEGKKERESERK------KERREREKRKREREKERKRERGKKEKK 87
W+ + + E+E + RK+ +K E K K R + EK R+ EK R++E +E++
Sbjct: 492 WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
Query: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147
++E+ +++R+E+E+K ++EK +++E+K + K ++ E+++E++ + K+
Sbjct: 552 KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE 611
Query: 148 ERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207
E+ +E+ EK +E++E+ + + +++ E+EE +E+E K ++ E+ ++ +K +E++E
Sbjct: 612 EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW 671
Query: 208 RKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
R++E+ +++E+K Q+++ RE+E +E++E+
Sbjct: 672 RQEEKIREQEKKIREQEEK---IREQEEMMQEQEEK 704
Score = 85.1 bits (209), Expect = 5e-17
Identities = 52/210 (24%), Positives = 119/210 (56%), Gaps = 12/210 (5%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Q ++E +R++E K +++ + + + +E + + + + E + + R ++
Sbjct: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE---ENELWNRLNQQ 297
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
+E K R+E++ +E EEK + ++++ +E+ +E +E+ R++E E++E+ R++EE
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 357
Query: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
E+E K R++ EE EKE K R++ E ++ +K RE +E+ +++ ++
Sbjct: 358 MWEKEEKMRRQ---------EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 408
Query: 215 KEERKKERQKDRQTNWREKERGKRERKERK 244
+EE+++E +K R+ R+++ K R+E K
Sbjct: 409 QEEKRQEEEKIREQEKRQEQEAKMWRQEEK 438
Score = 60.8 bits (146), Expect = 1e-09
Identities = 52/225 (23%), Positives = 108/225 (48%), Gaps = 19/225 (8%)
Query: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
E+ + + T+K+ K +R E + R+ + R E +K K + K + E
Sbjct: 176 ELEQALSAVATQKK-KADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVE 234
Query: 97 RKKRRREKENKEGEEKEKRKK---KEKKERGRTSKEGKER-----------ERKEERKRE 142
+K + KE + K +R K +++ + GKE E E R
Sbjct: 235 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRL 294
Query: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
+++ E+ + EK +E +E+ + + +++ E+EE+ +E+E K R++ E ++ +K R +
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
Query: 203 KERRERKKERKKKEE----RKKERQKDRQTNWREKERGKRERKER 243
+E K+E+ +++E K+E+ + ++ EKE RE +E+
Sbjct: 355 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 399
Score = 43.5 bits (101), Expect = 2e-04
Identities = 32/98 (32%), Positives = 57/98 (58%), Gaps = 5/98 (5%)
Query: 27 KPCTQPGWQSEIRER--EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKK 84
K C Q E E +E + R++ KK RE E K RE+E+ +E+E E+ E+ +K
Sbjct: 655 KMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI--REQEEMMQEQE-EKMWEQEEK 711
Query: 85 EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKE 122
+ E K +E+E K RR+E++ E E + ++++++ +E
Sbjct: 712 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 37.4 bits (85), Expect = 0.012
Identities = 31/152 (20%), Positives = 75/152 (49%), Gaps = 7/152 (4%)
Query: 101 RREKENKEGEEKEKRKKKEKKERGR---TSKEGKERERKEERKRE----ERKERERKKEE 153
+++K ++ EE K + E R T +E KE+ K + K + E+ E + +E
Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246
Query: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
+++ ER + +++ E + KE + K + + + R +++ E+ ++
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 306
Query: 214 KKEERKKERQKDRQTNWREKERGKRERKERKK 245
+K + +E+ ++++ RE+E RE++E+ +
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMR 338
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 110 bits (276), Expect = 9e-25
Identities = 64/222 (28%), Positives = 136/222 (61%), Gaps = 10/222 (4%)
Query: 34 WQSEIREREREIETRKEGKKERESERK----KERREREKRKREREKERKRERGKKEKKGE 89
W+ E + RE+E + R++ KK E K ++ RE EKR+ + E R+ E+ +++++
Sbjct: 419 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 478
Query: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERE--RKEERKREERKER 147
R+KE+ +++ R++E K ++EK +E+K R + K ++ E R++E K E++E+
Sbjct: 479 RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEK 538
Query: 148 ERKKEEREKERERK----ERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERK 203
R++EE +E+E K E K +E++++ +EE+ +E+E K R+++E+ R++ +K E++
Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598
Query: 204 ERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
E+ ++E +++E K Q+++ EK + + E+ R++
Sbjct: 599 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 640
Score = 110 bits (275), Expect = 1e-24
Identities = 70/247 (28%), Positives = 142/247 (57%), Gaps = 15/247 (6%)
Query: 8 RAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKER---- 63
RA + L + H+ K + + + E E+ R ++E + R++E+
Sbjct: 253 RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW 312
Query: 64 ----REREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKE 119
+E+E++ RE+E E+ RE+ +K ++ E E+E K RR+E+ E EEK +R ++
Sbjct: 313 EEKIQEQEEKIREQE-EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEM 371
Query: 120 KKERGRTSKEGKERERKEERKREER-KERERKKEEREKERERKERKKRERKQVGEKEEER 178
E KE K RE +E+ +E+ +E+E K++E EK RE+++R+++E K ++E+ R
Sbjct: 372 MWE-----KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 426
Query: 179 KEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKR 238
+++E+ ++++ R+E K + K R E K++ +++ R++E+ ++++ WR+KE+
Sbjct: 427 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHE 486
Query: 239 ERKERKK 245
+ K RK+
Sbjct: 487 QEKIRKQ 493
Score = 109 bits (273), Expect = 2e-24
Identities = 65/219 (29%), Positives = 135/219 (61%), Gaps = 9/219 (4%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERRER----EKRKREREKERKRERGKKEKKGE 89
W+ +I+E+E +I R++ +K RE E K R+E ++ K R++E E+ +K ++ E
Sbjct: 312 WEEKIQEQEEKI--REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLE 369
Query: 90 RKKEERERKKRRREKENKEGEE-KEKRKKKEKKERGRTSKEGKERERKEERKREERKERE 148
E+E K R E++ E E+ +E+ +K++++E+ R ++ +E+E K R+ E+ +E+E
Sbjct: 370 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 429
Query: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKE--RKERKKRERNRKERKKERERKERR 206
K E+EK+ R+E K E++++ E+E+ ++++E R+E K RE+ R+KE+ ++ +
Sbjct: 430 EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEK 489
Query: 207 ERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
RK+E K + +K ++ + +E++ ++E K R++
Sbjct: 490 IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQ 528
Score = 108 bits (270), Expect = 4e-24
Identities = 74/228 (32%), Positives = 137/228 (60%), Gaps = 18/228 (7%)
Query: 34 WQSEIRERE-REIETRKEGK----KERESERKKERREREKRKRE---REKERKRERGKKE 85
W+ E + R E+ KE K +E+ E++K R + EKR+ E RE+E+++E+ K
Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 418
Query: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
+ E K E+E K R +EK+ EEK ++K ++E R +E R+ ++ R++EE
Sbjct: 419 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 478
Query: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKE----RKERKKRERNRKERKKERE 201
++ K E+EK R+++E+ R+ +++ ++EE+ +E+E R+E K RE+ K R++E +
Sbjct: 479 RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEK 538
Query: 202 RKERRERKKERKKK----EERKKERQKDR--QTNWREKERGKRERKER 243
+E+ E +E+++K EE+ +E++K R + RE+E RE+KE+
Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEK 586
Score = 107 bits (267), Expect = 9e-24
Identities = 79/238 (33%), Positives = 145/238 (60%), Gaps = 36/238 (15%)
Query: 35 QSEIREREREIETRKEGKKERESERKKER-----------REREKRKREREKERKRERGK 83
Q +IRE+E E R+E +K RE E+++E+ RE+E++ RE+EK+ R+ K
Sbjct: 389 QEKIREQE---EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 445
Query: 84 ---KEK-KGERKKEERERKKRRREKENKEGE---------EKEKRKKKEKK----ERGRT 126
+EK + E K++E+E R+ EK ++ E E+EK +K+E+K E
Sbjct: 446 IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMH 505
Query: 127 SKEGKERERKEERKREERKERERK---KEEREKERERKERKKRERKQVGEKEEERKEKER 183
+E K RE++E+ R+E K RE++ +E+ EK RE++E + + +++GE+EE+ +E+E
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE- 564
Query: 184 KERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERK 241
K R++ E+ R++ +K RE+KE + R++E K E+ +K R+++ +E++ ++E K
Sbjct: 565 KMRRQEEKIREQEEKIREQKE-KIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621
Score = 104 bits (260), Expect = 6e-23
Identities = 63/226 (27%), Positives = 140/226 (61%), Gaps = 19/226 (8%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKRER--EKERKRER------GKKEK 86
+ +IRE+E +I ++E K R+ E E+ E+ +R+ E EKE K R K+EK
Sbjct: 320 EEKIREQEEKIREQEE-KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378
Query: 87 KGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKE 146
E +++ E++K R ++E ++ EEK + ++K +++ + ++ ++ +EE+ RE+ K+
Sbjct: 379 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 438
Query: 147 RERKKEE-REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERK-- 203
R++E+ E+E+ R+E K++E++++ +EE+ +E+E R+K + + +E+ +++E K
Sbjct: 439 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVW 498
Query: 204 -------ERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
++ E+ +E+++K R++E+ ++++ RE+E RE++E
Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEE 544
Score = 104 bits (259), Expect = 8e-23
Identities = 64/226 (28%), Positives = 141/226 (62%), Gaps = 20/226 (8%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER--K 91
W+ E + E+E +E ++E+E ++E + RE+ + R+KE+ E+ K K+ E+ +
Sbjct: 440 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWR 499
Query: 92 KEER--ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK--ER 147
+EE+ +++++ RE+E K ++EK +++E+K R +E K RE++E + +E K E+
Sbjct: 500 QEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIR---EQEEKIREQEEMMQEQEEKMGEQ 556
Query: 148 ERKKEEREKERERKERKKRERKQVGEKEEERKEKERK--ERKKRERNRKERKKERERK-- 203
E K +E+EK R ++E+ + + +++ E++E+ +E+E K E++++ R ++E +E+E K
Sbjct: 557 EEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW 616
Query: 204 -------ERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
E+ E+ +E+++K R++E+ +++ R++E +E +E
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 103 bits (258), Expect = 1e-22
Identities = 69/232 (29%), Positives = 137/232 (59%), Gaps = 22/232 (9%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERRER---------EKRKREREKERKRERGKKE 85
Q E R+ E+ KE K R+ E E+ E+ EK ++ RE E K +K
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKI 392
Query: 86 KKGERKKEERER---KKRRREKENKEGEEKEKRKKKEKKERGRTSK----EGKERERKEE 138
++ E K++E E+ +++R+E+E K ++EK +++E+K R + K E K E+++
Sbjct: 393 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI 452
Query: 139 RKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKE---RKERKKRERNRKE 195
R+ E+R+E+E + EK RE++E R+++++ E+E+ RK++E R+E K ++ K
Sbjct: 453 REEEKRQEQEEMWRQEEKIREQEE-IWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKI 511
Query: 196 RKKERE--RKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
R++E + R+E + R++E K +E+ +K R+++ +E++ G++E K +++
Sbjct: 512 REQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563
Score = 103 bits (256), Expect = 2e-22
Identities = 60/209 (28%), Positives = 130/209 (62%), Gaps = 8/209 (3%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E + RE+E R +KE+ E++K R++ EK R+ EK +E EK E++++
Sbjct: 465 WRQEEKIREQEEIWR---QKEKMHEQEKIRKQEEKVWRQEEKMHDQE----EKIREQEEK 517
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
++++ RE+E K E++EK +++E+ + + K G++ E+ +E+++ R+E E+ +E+
Sbjct: 518 MWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQE-EKIREQ 576
Query: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
EK RE+KE+ + + +++ E+EE+ +E+E +++ E+ ++ +K E++E+ + ++E+
Sbjct: 577 EEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 636
Query: 214 KKEERKKERQKDRQTNWREKERGKRERKE 242
+++E K Q+ R EK + +E E
Sbjct: 637 RRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 101 bits (251), Expect = 7e-22
Identities = 73/254 (28%), Positives = 150/254 (59%), Gaps = 22/254 (8%)
Query: 13 LNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGK----KERESERKKERREREK 68
L ELQ VS ++ W + + +++ E R+E K +E+ E++++ RE+E+
Sbjct: 270 LGKELQSVSAKLQAQVEENELW-NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
Query: 69 RKREREKERKRERG---KKEKKGERKKE---ERERKKRRREKENKEGEEK----EKRKKK 118
+ RE+E++ +R+ +KE+K R++E E+E K RR E+ E EEK E++ +
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHE 388
Query: 119 EKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEER 178
++K R + K +E + +E+ KR+E++ + ++EE+ +E+E K R++ ++ E++
Sbjct: 389 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE 448
Query: 179 KEKERKERKKRERNRKERKKERERKER---RERKK----ERKKKEERKKERQKDRQTNWR 231
+EK R+E K++E+ R++E+ R++ R+++K E+ +K+E K RQ+++ +
Sbjct: 449 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQE 508
Query: 232 EKERGKRERKERKK 245
EK R + E+ R++
Sbjct: 509 EKIREQEEKMWRQE 522
Score = 86.3 bits (212), Expect = 2e-17
Identities = 56/221 (25%), Positives = 130/221 (58%), Gaps = 16/221 (7%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Q ++E +R++E K +++ + + + +E + + + + E + + R ++
Sbjct: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE---ENELWNRLNQQ 297
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
+E K R+E++ +E EEK + ++++ +E+ +E +E+ R++E E++E+ R++EE
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 357
Query: 155 EKERERKERKKRERKQVGEKEE-----ERKEKERKERKKRERNRKERKKERERKERRER- 208
E+E K R+ E + EKEE E K E+++ +++E R+E +K RE+++R+E+
Sbjct: 358 MWEKEEKMRRLEE--MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 415
Query: 209 ----KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
++E K +E+ +K R+++++ WR++E+ + K R++
Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKM-WRQEEKIHEQEKIREE 455
Score = 77.0 bits (188), Expect = 1e-14
Identities = 53/211 (25%), Positives = 116/211 (54%), Gaps = 16/211 (7%)
Query: 46 ETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKE 105
E +++ K +E + E + E + +E +RK ER K ++ + E + KE
Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG----KE 273
Query: 106 NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKE-----RER 160
+ K + + +E + R +++ +E+ ++E K +E +E+ +++EE+ +E RE+
Sbjct: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
Query: 161 KERKKRERKQVGEKEEERK-------EKERKERKKRERNRKERKKERERKERRERKKERK 213
+E+ +R+ + + EKEE+ + EKE K R+ E ++ +K RE +E+ +++ +
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIR 393
Query: 214 KKEERKKERQKDRQTNWREKERGKRERKERK 244
++EE+++E +K R+ R+++ K R+E K
Sbjct: 394 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 424
Score = 58.9 bits (141), Expect = 4e-09
Identities = 50/229 (21%), Positives = 111/229 (48%), Gaps = 21/229 (9%)
Query: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
E+ + + T+K+ K +R E + R+ + R E +K K + K + E
Sbjct: 176 ELEQALSAVATQKK-KADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVE 234
Query: 97 RKKRRREKENKEGEEKEKRKK---KEKKERGRTSKEGKER-----------ERKEERKRE 142
+K + KE + K +R K +++ + GKE E E R
Sbjct: 235 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRL 294
Query: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
+++ E+ + EK +E +E+ + + +++ E+EE+ +E+E K R++ E ++ +K R +
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
Query: 203 KERRERKKERKKK------EERKKERQKDRQTNWREKERGKRERKERKK 245
+E K+E+ ++ E+ +K R+ + + + +EK R + E+++ ++
Sbjct: 355 EEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE 403
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 110 bits (274), Expect = 1e-24
Identities = 53/205 (25%), Positives = 138/205 (67%), Gaps = 2/205 (0%)
Query: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK-KR 100
E+E + RK+ ++ E E + +++E + +K+E + ++ E+ +++++ R++EE+ K K
Sbjct: 224 EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE 283
Query: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERER 160
+ E+E + GE++E+ +++E++ R + + ++ E+ E++ + K+ E+ E++E+ E+
Sbjct: 284 QTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQ 343
Query: 161 KERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKK 220
KE+ ++ +Q+GE+EE+ +++E + RK+ E+ RK+ ++ R+++E+ RK+E + E++++
Sbjct: 344 KEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQM-RKQEEQMGEQKEQ 402
Query: 221 ERQKDRQTNWREKERGKRERKERKK 245
++ Q +E++ G+++ + RK+
Sbjct: 403 MGEQKEQMREQEEQMGEQKEQMRKQ 427
Score = 108 bits (270), Expect = 4e-24
Identities = 55/209 (26%), Positives = 139/209 (66%), Gaps = 6/209 (2%)
Query: 35 QSEIREREREIETRKEG-KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
+ ++ E+E +++ ++E +K+ E RK+E + RE+ ++ RE+E + + K++ E++++
Sbjct: 233 EEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT--EQEEQ 290
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
E++++ RE+E + E++E+ +++E++ R + + GK+ E+ E+K + +++E+ ++
Sbjct: 291 TGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQ 350
Query: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
E+ E++E+ +++ +QV ++EE+ +++E + RK+ E+ RK+ ++ E+KE+ +KE+
Sbjct: 351 EEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQM 410
Query: 214 KKEERKKERQKDRQTNWREKERGKRERKE 242
+++E + QK++ R++E E+KE
Sbjct: 411 REQEEQMGEQKEQM---RKQEEHMGEQKE 436
Score = 107 bits (267), Expect = 9e-24
Identities = 53/225 (23%), Positives = 140/225 (62%), Gaps = 10/225 (4%)
Query: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90
Q G E E+ E E + + ++E+ E++++ R++E++ E+E++ +++ + +K+ E+
Sbjct: 197 QEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQ 256
Query: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
+++ E+ + + E+ ++ E+ K+K++ ++E +E + RE++E+ + +E + RE++
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE 316
Query: 151 KEEREKER----------ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER 200
++ RE+E E+KE+ +++Q+ ++EE+ E+E + +K+ E+ RK+ ++ R
Sbjct: 317 EQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR 376
Query: 201 ERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+++E+ +++E+ +K+E + QK++ +E+ R + E+ +K
Sbjct: 377 KQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421
Score = 105 bits (262), Expect = 4e-23
Identities = 55/224 (24%), Positives = 150/224 (66%), Gaps = 14/224 (6%)
Query: 35 QSEIREREREIETRKEGKKERESERKKER---REREKRKRERE---KERKRERGKKE-KK 87
+ ++RE+E ++ ++ +E+E + +++ RE+E + RE+E +E++ + G++E +
Sbjct: 142 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQM 201
Query: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147
GE++++ E++++ +++E + GE++E+ +K+E++ + + K+ E+ ++++ + RK+
Sbjct: 202 GEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261
Query: 148 ERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207
E+ +E+ E+ RE++E+ ++++Q E+EE+ E+E + R++ E+ R++ ++ RE++E+
Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQT-EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMR 320
Query: 208 RKKERKKKEERKKERQKD-----RQTNWREKER-GKRERKERKK 245
++E+ K+E + QK+ ++ W+++E+ G++E + +K+
Sbjct: 321 EQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQ 364
Score = 104 bits (259), Expect = 8e-23
Identities = 54/221 (24%), Positives = 147/221 (66%), Gaps = 10/221 (4%)
Query: 35 QSEIREREREIETRKEGKKERESERKKER---REREKRKREREKERKRERGK-KEKKGER 90
+ ++RE+E ++ ++ +E+E + +++ RE+E + RE+E + + + G+ +E++G+
Sbjct: 100 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 159
Query: 91 KKEE---RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147
+++E RE++ + RE+E + E++ + +++E + + + G++ E+ E++ + +K+
Sbjct: 160 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQE 219
Query: 148 ERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207
E+ E+ E+ R+++E+ + +QV ++EE+ +++E + RK+ E+ R++ ++ RE++E+
Sbjct: 220 EQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQML 279
Query: 208 RKKERKKKEER---KKERQKDRQTNWREKERGKRERKERKK 245
++KE+ ++EE+ ++E+ ++++ RE+E RE++E+ +
Sbjct: 280 KQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMR 320
Score = 103 bits (258), Expect = 1e-22
Identities = 56/216 (25%), Positives = 145/216 (67%), Gaps = 13/216 (6%)
Query: 35 QSEIREREREIETRKEGKKERESERKKER---REREKRKREREKERKRERGK-KEKKGER 90
+ ++RE+E ++ ++ +E+E + +++ RE+E + RE+E + + + G+ +E++G+
Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180
Query: 91 KKEE---RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERE--RKEERKREERK 145
+++E RE++ + E+E + GE++E+ ++E++ + + + G++ E RK+E + E++
Sbjct: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
Query: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER 205
E+ +K+EE+ +++E + RK+ E Q+ E+EE+ +E+E + K++E+ +E + + ++
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEE--QMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM 298
Query: 206 RERKKERKKKEERKKERQKDRQTNWREKERGKRERK 241
RE++++ +++EE+ +E+++ Q +E++ GK+E +
Sbjct: 299 REQEEQMREQEEQMREQEE--QMREQEEQMGKQEEQ 332
Score = 102 bits (255), Expect = 2e-22
Identities = 54/221 (24%), Positives = 147/221 (66%), Gaps = 10/221 (4%)
Query: 35 QSEIREREREIETRKEGKKERESERKKER---REREKRKREREKERKRERGK-KEKKGER 90
+ ++RE+E ++ ++ +E+E + +++ RE+E + RE+E + + + G+ +E++G+
Sbjct: 93 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 152
Query: 91 KKEE---RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147
+++E RE++ + RE+E + E++ + +++E + R + + G++ + E++ + ++
Sbjct: 153 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE 212
Query: 148 ERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207
E+ +++ E+ E++E+ +++ +Q+GE+EE+ +++E + +K+ E+ RK+ ++ RE++E+
Sbjct: 213 EQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMR 272
Query: 208 RKKER--KKKEERKKERQK-DRQTNWREKERGKRERKERKK 245
++E+ K+KE+ ++E Q +++ RE+E RE++E+ +
Sbjct: 273 EQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMR 313
Score = 100 bits (250), Expect = 9e-22
Identities = 52/217 (23%), Positives = 135/217 (62%), Gaps = 7/217 (3%)
Query: 35 QSEIREREREIETRKEGKKERES---ERKKERREREKRKREREKERKRERGKKEKKGERK 91
+ ++RE+E ++ ++ +E+E E++ + E+E + E+E++ + + +K+ E+
Sbjct: 163 EGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQM 222
Query: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
E+ E+ +++ E+ ++ E+ +K++++ +K+ + K+ ++ +EE+ RE+ ++ ++K
Sbjct: 223 GEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
Query: 152 EEREKER---ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
E+ E+E E++E+ + + +Q+ E+EE+ +E+E + R++ E+ K+ ++ E+KE+
Sbjct: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
Query: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+KE+ K+E + Q+++ E+ R K+E + RK+
Sbjct: 343 QKEQMWKQEEQMGEQEEQMQKQEEQVR-KQEEQMRKQ 378
Score = 98.2 bits (243), Expect = 6e-21
Identities = 51/216 (23%), Positives = 141/216 (65%), Gaps = 10/216 (4%)
Query: 35 QSEIREREREIETRKEGKKERESERKKER---REREKRKREREKERKRERGK-KEKKGER 90
+ ++RE+E ++ ++ +E+E + +++ RE+E + RE+E + + + G+ +E++G+
Sbjct: 65 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 124
Query: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
+++E + +++ + +EG+ +E+ + ++E +EG+ RE++ + + +E + RE++
Sbjct: 125 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 184
Query: 151 KEEREKERERKERKKR---ERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207
+ RE+E + E++ + + +Q+GE+EE+ +++E + ++ E+ RK+ ++ E++E+ +
Sbjct: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ 244
Query: 208 RKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
+++E+ +K+E + +Q+++ RE+E RE++E+
Sbjct: 245 KQEEQVQKQEEQMRKQEEQM---REQEEQMREQEEQ 277
Score = 97.8 bits (242), Expect = 7e-21
Identities = 45/217 (20%), Positives = 144/217 (66%), Gaps = 7/217 (3%)
Query: 35 QSEIREREREIETRKEGKKERES---ERKKERREREKRKREREKERKRER---GKKEKKG 88
+ ++RE+E ++ ++ +E+E E++ + E+E++ E+E++ +++ G++E++
Sbjct: 170 EGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQM 229
Query: 89 ERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE 148
+++E+ ++ + +K+ ++ +++E++ +K++++ ++ +E+E + +++E+ ++ E
Sbjct: 230 RKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEE 289
Query: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
+ E+ E+ RE++E+ + + +Q+ E+EE+ +E+E + K+ E+ +++++ E+KE+ +
Sbjct: 290 QTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWK 349
Query: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
++E+ ++E + ++Q++ Q +E++ K+E + RK+
Sbjct: 350 QEEQMGEQEEQMQKQEE-QVRKQEEQMRKQEEQMRKQ 385
Score = 96.7 bits (239), Expect = 2e-20
Identities = 43/217 (19%), Positives = 140/217 (64%), Gaps = 6/217 (2%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE- 93
+ ++RE+E ++ ++ E+E + ++ + +K++ + ++ ++ R ++E+ GE++++
Sbjct: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
Query: 94 --ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
+ E+ +++ E+ K+ E+ +++++ +++ + K+ ++ E++E+ +E + RE+++
Sbjct: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEE 303
Query: 152 EEREKE---RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
+ RE+E RE++E+ + + +Q+G++EE+ E++ + +++E+ K+ ++ E++E+ ++
Sbjct: 304 QMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQK 363
Query: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
++E+ +K+E + +Q+++ E+ R + E+ +K
Sbjct: 364 QEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQK 400
Score = 90.9 bits (224), Expect = 9e-19
Identities = 51/216 (23%), Positives = 133/216 (61%), Gaps = 5/216 (2%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKE---RKRERGKKEKKGERK 91
Q I+E +R++ET K + R++E + RE+ + RE+E R++E +E++G+ +
Sbjct: 31 QLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 90
Query: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
++E + +++ + +EG+ +E+ + ++E +EG+ RE++ + + +E + RE++
Sbjct: 91 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 150
Query: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKE 211
+ RE+E + +E++ + R+Q G+ E+ + +E + RE+ + ++E + E+ E+ E
Sbjct: 151 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGE 210
Query: 212 RKKKEERKKER--QKDRQTNWREKERGKRERKERKK 245
++++ ++++E+ +++ Q +E++ G++E + +K+
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ 246
Score = 82.0 bits (201), Expect = 4e-16
Identities = 55/229 (24%), Positives = 137/229 (59%), Gaps = 21/229 (9%)
Query: 36 SEIREREREIETRK--------EGKKERESER---KKERREREKRKREREKE---RKRER 81
+E++E + +ET K E K++ E+++ +E + RE+ + RE+E R++E
Sbjct: 14 AELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEG 73
Query: 82 GKKEKKGERKKEE---RERKKRRREKE----NKEGEEKEKRKKKEKKERGRTSKEGKERE 134
+E++G+ +++E RE++ + RE+E +EG+ +E+ + ++E +EG+ RE
Sbjct: 74 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 133
Query: 135 RKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRK 194
++ + + +E + RE++ + RE+E + +E++ + R+Q G+ E+ + +E + RE+ +
Sbjct: 134 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 193
Query: 195 ERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
++E + E+ E+ E++++ ++++E+ +++ R++E E++E+
Sbjct: 194 MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQ 242
Score = 80.5 bits (197), Expect = 1e-15
Identities = 48/212 (22%), Positives = 128/212 (60%), Gaps = 4/212 (1%)
Query: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK-KEKKGERKKEER 95
E++E+ E++ + + +SE + +E KRK E +K + G+ +E++G+ +++E
Sbjct: 8 ELKEKNAELQEELQLVETEKSEIQLHIKEL-KRKLETDKIPLPQEGQVREQEGQVREQEG 66
Query: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
+ +++ + +EG+ +E+ + ++E +EG+ RE++ + + +E + RE++ + RE
Sbjct: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
Query: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER--RERKKERK 213
+E + +E++ + R+Q G+ E+ + +E + RE+ + R++E + +E+ + R++E +
Sbjct: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
Query: 214 KKEERKKERQKDRQTNWREKERGKRERKERKK 245
+E+ + +++ Q +E++ G++E + +K+
Sbjct: 187 VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQ 218
Score = 75.5 bits (184), Expect = 4e-14
Identities = 48/201 (23%), Positives = 118/201 (58%), Gaps = 9/201 (4%)
Query: 50 EGKKERESERKKERREREKRKRE-----REKERKRERGK--KEKKGERKKEERERKKRRR 102
E KE+ +E ++E + E K E +E +RK E K ++G+ +++E + +++
Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
Query: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKE 162
+ +EG+ +E+ + ++E +EG+ RE++ + + +E + RE++ + RE+E + +E
Sbjct: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
Query: 163 RKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER--RERKKERKKKEERKK 220
++ + R+Q G+ E+ + +E + RE+ + R++E + +E+ + R++E + +E+ +
Sbjct: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
Query: 221 ERQKDRQTNWREKERGKRERK 241
R+++ Q +E + G++E +
Sbjct: 187 VREQEGQMGEQEGQMGEQEEQ 207
Score = 58.5 bits (140), Expect = 5e-09
Identities = 30/87 (34%), Positives = 60/87 (68%), Gaps = 5/87 (5%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E + E+E + +K+ ++ R+ E + ++E + RK+E E+ RK+E E+ GE+K++
Sbjct: 348 WKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQE-EQMRKQE----EQMGEQKEQ 402
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEK 120
E+K++ RE+E + GE+KE+ +K+E+
Sbjct: 403 MGEQKEQMREQEEQMGEQKEQMRKQEE 429
Score = 33.1 bits (74), Expect = 0.23
Identities = 27/101 (26%), Positives = 55/101 (54%), Gaps = 3/101 (2%)
Query: 141 REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER 200
R +E + K E ++E + E +K E Q+ KE +RK + K +E +E++ +
Sbjct: 3 RITNEELKEKNAELQEELQLVETEKSEI-QLHIKELKRKLETDKIPLPQEGQVREQEGQV 61
Query: 201 ERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERK 241
+E + R++E + +E+ + R+++ Q RE+E RE++
Sbjct: 62 REQEGQVREQEGQVREQEGQVREQEGQV--REQEGQVREQE 100
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 109 bits (273), Expect = 2e-24
Identities = 59/213 (27%), Positives = 120/213 (56%), Gaps = 3/213 (1%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+ I E + E+ ++ + +E + + E ++E +RE+G E K EE
Sbjct: 200 RGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEE 259
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERG--RTSKEGKERERKEERKREERKERERKKE 152
++++ E+ E EE+E+ K ++ K+ R E +E+ +ER+R E +ERER +E
Sbjct: 260 EDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMRE 319
Query: 153 EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER-RERKKE 211
E ++ E ++R K E K+ E+ + KE+E++ ++R+R ++E K+ E ++R R ++E
Sbjct: 320 EEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEE 379
Query: 212 RKKKEERKKERQKDRQTNWREKERGKRERKERK 244
+ K EE+K+ +Q + + + ++ + K E+ E+K
Sbjct: 380 KAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQK 412
Score = 103 bits (256), Expect = 2e-22
Identities = 64/212 (30%), Positives = 122/212 (57%), Gaps = 6/212 (2%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKK--GERKKEERE 96
+E ERE + + E+ E KER E E+ + E E ER+R + +++KK ER + E E
Sbjct: 240 QEEEREQGSDEISHHEKMEEEDKERAEAERARLEAE-ERERIKAEQDKKIADERARIEAE 298
Query: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
K +E+E +E EE+E+ +++EK+ + +E +R E ++ ++E +R EER++
Sbjct: 299 EKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQR 358
Query: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERK-ERRERKKERKKK 215
+E ++R ER++ +EEE+ + E ++R K+ +K +E + K E+ E+K E K
Sbjct: 359 IKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWV 418
Query: 216 EERKKERQKDRQTNWRE--KERGKRERKERKK 245
E+K + K + ++ +E+G + + +R+K
Sbjct: 419 NEKKAQEDKLQTAVLKKQGEEKGTKVQAKREK 450
Score = 99.0 bits (245), Expect = 3e-21
Identities = 72/261 (27%), Positives = 122/261 (46%), Gaps = 54/261 (20%)
Query: 35 QSEIREREREIETRKEGKKERESE-----------RKKERREREKRKREREKERKRERGK 83
++E E+E + E+R+E + E+E R E ++E +++E E+E K +RG
Sbjct: 143 ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS 202
Query: 84 ----------KEKKGERKKE-----------ERERKKRRREKENKEGE----EKEKRKKK 118
+EK E ++E E K+ E+E E EK + + K
Sbjct: 203 IGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDK 262
Query: 119 EKKERGRTSKEGKERER---------KEERKREERKERERKKEEREKERERKERKKRERK 169
E+ E R E +ERER +ER R E +E+ +E +E E +ER + E K
Sbjct: 263 ERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEK 322
Query: 170 QVGEKEEERKEKER---------KERKKRERNRKERKKERERKERRERKKERKKKEERKK 220
+ E+ + KE+E+ KE +KR ++R KE E++ ER++ R ++EE+ K
Sbjct: 323 RAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAK 382
Query: 221 ERQKDRQTNWREKERGKRERK 241
++ R EK+ +E K
Sbjct: 383 VEEQKRNKQLEEKKHAMQETK 403
Score = 96.7 bits (239), Expect = 2e-20
Identities = 65/229 (28%), Positives = 119/229 (51%), Gaps = 18/229 (7%)
Query: 35 QSEIREREREIETRKEG------KKERESERKKERREREKRKREREKERKRERGKKEK-K 87
Q E+ E+ E+++E + SE K+ ERE+ E K E KE+ +
Sbjct: 207 QVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAE 266
Query: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERG--RTSKEGKERERKEERKREERK 145
ER + E E ++R + +++K+ ++ R + E+K R +E +ERER E ++ +
Sbjct: 267 AERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAE 326
Query: 146 ERERKKEEREKERERKERKKRERKQVGE-----KEEERKEKERKERKKRERNRKERKKER 200
ER+R KEE ++ E ++R K E K+ E KEEE++ E ++R + E K + +E+
Sbjct: 327 ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQ 386
Query: 201 ERKERRERKK----ERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+R ++ E KK E K K E+ +++ + + N ++ + K + KK
Sbjct: 387 KRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKK 435
Score = 95.5 bits (236), Expect = 4e-20
Identities = 58/213 (27%), Positives = 119/213 (55%), Gaps = 11/213 (5%)
Query: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKG---ERKKE 93
EI E+ E KE + + + E RER K +++++ +R R + E+K ER++
Sbjct: 250 EISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERR 309
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
E E ++R RE+E + EE+++ K++EK + +ER+R +E ++ +ER+R KEE
Sbjct: 310 EAEERERMREEEKRAAEERQRIKEEEK-------RAAEERQRIKEEEKRAAEERQRIKEE 362
Query: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
++ E ++R + E ++ + EE+++ K+ +E+K + K + ++ E+K + E+K
Sbjct: 363 EKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK 422
Query: 214 KKEERKKERQKDRQTNWR-EKERGKRERKERKK 245
+E++ + +Q + K + KRE+ + K
Sbjct: 423 AQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDK 455
Score = 94.4 bits (233), Expect = 8e-20
Identities = 69/222 (31%), Positives = 129/222 (58%), Gaps = 15/222 (6%)
Query: 37 EIRERER-EIETRKEGKKER---ESERKKERREREKRK-REREKERKRERGKKEKKGERK 91
E ERER + E K+ ER E+E K +ERE+R+ ERE+ R+ E+ E++ K
Sbjct: 273 EAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIK 332
Query: 92 KEER---ERKKRRREKENKEGEEKEKRKKKEKK---ERGRTSKEGKERERKEERKREERK 145
+EE+ E ++R +E+E + EE+++ K++EK+ ER R E +E+ + EE+KR ++
Sbjct: 333 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQL 392
Query: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKR--ERNRK-ERKKERER 202
E ++ + K + K +K E K V EK+ + + + KK+ E+ K + K+E+ +
Sbjct: 393 EEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQ 452
Query: 203 KERRERKKERKKKEERKKERQ-KDRQTNWREKERGKRERKER 243
+++ KKE K E+ KK+++ K+ ++ ++++G E K +
Sbjct: 453 EDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQ 494
Score = 89.4 bits (220), Expect = 3e-18
Identities = 56/203 (27%), Positives = 108/203 (53%), Gaps = 1/203 (0%)
Query: 27 KPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEK 86
K Q + E ERER E K +ER+ +++E+R E+R+R +E+E++ ++
Sbjct: 300 KAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI 359
Query: 87 KGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKE 146
K E K+ ER++ R E+E K E++KR K+ +E+ +E K + K E+K E +
Sbjct: 360 KEEEKRAAEERQRARAEEEEKAKVEEQKR-NKQLEEKKHAMQETKIKGEKVEQKIEGKWV 418
Query: 147 RERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERR 206
E+K +E + + +++ E+ + + E+ ++++ KK E ++ KK++E KE
Sbjct: 419 NEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEV 478
Query: 207 ERKKERKKKEERKKERQKDRQTN 229
+ +RKK K + + T+
Sbjct: 479 KSFMDRKKGFTEVKSQNGEFMTH 501
Score = 86.3 bits (212), Expect = 2e-17
Identities = 70/272 (25%), Positives = 130/272 (47%), Gaps = 66/272 (24%)
Query: 40 EREREIETRKEGKKERESERKKERR---EREKRKREREKERKRERGKKEKKGERKKEERE 96
ER+R E K +ER+ +++E+R ER++ + E E++ K E K+ K+ E KK +
Sbjct: 341 ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQ 400
Query: 97 RKKRRREKENKEGEEK---EKRKKKEKKERGRTSKEGKERERKEERKREERKERER--KK 151
K + EK ++ E K EK+ +++K + K+G+E+ K + KRE+ +E + KK
Sbjct: 401 ETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKK 460
Query: 152 EEREKERERKERKKRE---------------------------------------RKQVG 172
EE + E+ +K+++ +E R V
Sbjct: 461 EEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVD 520
Query: 173 EKEEE---------RKEKERKERKKRERNRKERKKERE----------RKERRERKKERK 213
KE E R E+ R+ R + E E+ K+++ +K+R ER+K +
Sbjct: 521 TKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLE 580
Query: 214 KKEERKKERQKDRQTNWREKERGKRERKERKK 245
++E+R+K+ + DR+ E++R +E ER++
Sbjct: 581 EEEQRRKQEEADRKLREEEEKRRLKEEIERRR 612
Score = 85.5 bits (210), Expect = 4e-17
Identities = 59/208 (28%), Positives = 111/208 (53%), Gaps = 24/208 (11%)
Query: 34 WQSEIREREREIET---RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKG-E 89
W +E + +E +++T +K+G+++ + K + +E + +++E K E+ KK+K+ E
Sbjct: 417 WVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKE 476
Query: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEK----KERGRTSKEGKE------------- 132
K +RKK E +++ GE + K + + GR S + KE
Sbjct: 477 EVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRL 536
Query: 133 ---RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKR 189
R R+ E + EE ++ ++K++E E E ++K+ ER++V E+EE+R+++E +RK R
Sbjct: 537 EELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLR 596
Query: 190 ERNRKERKKERERKERRERKKERKKKEE 217
E K R KE + R E ++R+K E
Sbjct: 597 EEEEKRRLKEEIERRRAEAAEKRQKMPE 624
Score = 80.9 bits (198), Expect = 9e-16
Identities = 65/249 (26%), Positives = 119/249 (47%), Gaps = 55/249 (22%)
Query: 52 KKERESERKKERREREKR--------------KREREKERKRERGKKEKKGERKKEERE- 96
++ER +R +E ER+K +R + + E +KE+K E ++E E
Sbjct: 103 REERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEI 162
Query: 97 ----------RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK- 145
+K R+ E + E+KEK +++E+K + + E + EE+ E ++
Sbjct: 163 EETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEE 222
Query: 146 -------------ERERKKEEREK-----------ERERKERKKRERKQVGEKEEER--K 179
E +++EERE+ E E KER + ER ++ +E ER
Sbjct: 223 TVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKA 282
Query: 180 EKERK---ERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERG 236
E+++K ER + E K +ERER+E ER++ R++++ +ERQ+ ++ R E
Sbjct: 283 EQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEER 342
Query: 237 KRERKERKK 245
+R ++E K+
Sbjct: 343 QRIKEEEKR 351
Score = 70.5 bits (171), Expect = 1e-12
Identities = 64/280 (22%), Positives = 115/280 (41%), Gaps = 72/280 (25%)
Query: 37 EIRERERE---IETRKEGKKERESERKKERREREKRKREREKERKRER------------ 81
E+R ++RE +E + + + + ++ RER +R R+ +K+E
Sbjct: 9 ELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEV 68
Query: 82 ---------------------------------GKKEKKGERKKEERERKK--------- 99
++E++ +R +E ER+K
Sbjct: 69 NAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDA 128
Query: 100 ------RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
RR + + E E EK +K E ++ R E E K +K + R E KKE+
Sbjct: 129 SLSLPSRRMQNDTAENETTEKEEKSESRQE-RYEIEETETVTKSYQKNDWRDAEENKKED 187
Query: 154 REKERERKERKKR---ERKQVGEKEEERKEKERKER-----KKRERNRKERKKERERKER 205
+EKE E +E+ KR QV EE+ + ++E K + + +E K+E ER++
Sbjct: 188 KEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQG 247
Query: 206 RERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+ +K EE KER + + +ER + + ++ KK
Sbjct: 248 SDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKK 287
Score = 68.9 bits (167), Expect = 4e-12
Identities = 77/313 (24%), Positives = 126/313 (40%), Gaps = 106/313 (33%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKER----------------- 77
+ E+R I ++ E E+ R++ RR R++R R++++E
Sbjct: 15 REEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSV 74
Query: 78 -----------------------KRERGKKEKKGERKKEERERKK--------------- 99
+R ++E++ +R +E ER+K
Sbjct: 75 PDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPS 134
Query: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERE 159
RR + + E E EK +K E ++ R E E K +K + R E KKE++EKE E
Sbjct: 135 RRMQNDTAENETTEKEEKSESRQE-RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEE 193
Query: 160 RKERKKR------------ERK--------------------QVGEKEEERK-------- 179
+E+ KR E K + ++EEER+
Sbjct: 194 EEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISH 253
Query: 180 ----EKERKERKKRERNRKERKKERERKERRERKK---ERKKKEERKKERQKDRQTNWRE 232
E+E KER + ER R E +ERER + + KK ER + E +K ++R+ RE
Sbjct: 254 HEKMEEEDKERAEAERARLE-AEERERIKAEQDKKIADERARIEAEEKAAAQERER--RE 310
Query: 233 KERGKRERKERKK 245
E +R R+E K+
Sbjct: 311 AEERERMREEEKR 323
Score = 62.8 bits (151), Expect = 3e-10
Identities = 41/200 (20%), Positives = 97/200 (48%), Gaps = 20/200 (10%)
Query: 54 ERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKE 113
ER E ++++RE + + ER ++ + ++E ER++ R+ + R++++E G+ +
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64
Query: 114 KRKKKEKK----ERGRTSKEGKERERKEE----RKREERKERERKKEEREKERERKERKK 165
+ + + E +T+ + E +E + R+ER +K+ + ER++
Sbjct: 65 QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQK----- 119
Query: 166 RERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKD 225
E + + +R +N + E++E+ E ++ER + EE + +
Sbjct: 120 -------EFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSY 172
Query: 226 RQTNWREKERGKRERKERKK 245
++ +WR+ E K+E KE+++
Sbjct: 173 QKNDWRDAEENKKEDKEKEE 192
Score = 62.4 bits (150), Expect = 3e-10
Identities = 48/175 (27%), Positives = 77/175 (44%), Gaps = 10/175 (5%)
Query: 14 NTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKRER 73
N E H ++PG ++ + +E E + E K E E R+R
Sbjct: 495 NGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLE----------ELRRRRG 544
Query: 74 EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
E E + K+K+ E E E KK+R E+ EE+++RK++E + R +E +
Sbjct: 545 ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRL 604
Query: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKK 188
+ + ER+R E E+ +K E ++K K K K EER E K +K
Sbjct: 605 KEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQK 659
Score = 57.4 bits (137), Expect = 1e-08
Identities = 39/153 (25%), Positives = 74/153 (48%), Gaps = 9/153 (5%)
Query: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95
+E++ + E T K E R R + ++ E + + + +E + R + E
Sbjct: 489 TEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETES 548
Query: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
E ++ ++K+ + E E+ KKK ++ R K E +E+R+++E E +RK E E
Sbjct: 549 EEFEKLKQKQQEAALELEELKKKREERR-------KVLEEEEQRRKQE--EADRKLREEE 599
Query: 156 KERERKERKKRERKQVGEKEEERKEKERKERKK 188
++R KE +R R + EK ++ E + KK
Sbjct: 600 EKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 632
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 109 bits (272), Expect = 2e-24
Identities = 65/186 (34%), Positives = 100/186 (53%), Gaps = 12/186 (6%)
Query: 56 ESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR----REKENKEGEE 111
E + K +R E + ER K+ K+ER ++EK+ ER++EERERK+RR REKE E
Sbjct: 229 ELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE 288
Query: 112 KEKRKKKEKKERGRTSKE--GKERERKEERKREERKERERKKEEREKERERKERKKRERK 169
+ KR + + RTS + R+ K R RE R+ R R + R + +R ERK R R
Sbjct: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDR-RRSRSHDRSERKHRSRS 347
Query: 170 QVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQ-T 228
+ + + R K K R K ++R+++R+ KE+ +R + KK + R+K + T
Sbjct: 348 RDRRRSKSRDRKSYKHRSK----SRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDT 403
Query: 229 NWREKE 234
N KE
Sbjct: 404 NTESKE 409
Score = 107 bits (267), Expect = 9e-24
Identities = 57/197 (28%), Positives = 108/197 (54%), Gaps = 11/197 (5%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
++ + E + ++ R E + +R+ KKE++ERE EREKER+RER ++E+K R++EE
Sbjct: 224 KATVEELKEKLRKRTE-EPDRDERLKKEKQERE----EREKEREREREERERKRRREEEE 278
Query: 95 RERKK---RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
RE+++ R R K ++ R + R R K + RER+ R R+ R+ R +
Sbjct: 279 REKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR 338
Query: 152 EERE---KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
ER+ + R+R+ K R+RK + + R ++ ++ K++E+ + KK + RE+
Sbjct: 339 SERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREK 398
Query: 209 KKERKKKEERKKERQKD 225
+ E E ++ + + +
Sbjct: 399 QSEDTNTESKESDTKNE 415
Score = 100 bits (248), Expect = 2e-21
Identities = 61/208 (29%), Positives = 114/208 (54%), Gaps = 13/208 (6%)
Query: 38 IREREREIETRKEGKKERESERKKERREREKRK-REREKERKRERGKKEKKGERKKEERE 96
+ + + ++ GK+ + K E K K R+R +E R+ K++K ER++ E+E
Sbjct: 201 VGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKE 260
Query: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
R++ R E+E K E+E+R+K+ ++R R K + R R R + R R R +R +
Sbjct: 261 REREREERERKRRREEEEREKERARDRER-RKRSRSRSRHSSRTSDRRCSRSR-DHKRSR 318
Query: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNR-KERKKERERKERRERKKERKKK 215
RER+ + R+R++ + +R ERK R R+R + R K R+RK + R K R ++
Sbjct: 319 SRERRRSRSRDRRR-------SRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDRE 371
Query: 216 EERKKERQKDRQTNWREK--ERGKRERK 241
++RK + ++ R ++ ++ + G RE++
Sbjct: 372 QDRKSKEKEKRGSDDKKSSVKSGSREKQ 399
Score = 96.7 bits (239), Expect = 2e-20
Identities = 58/177 (32%), Positives = 98/177 (55%), Gaps = 15/177 (8%)
Query: 72 EREKERKRERGKKEKKGER-KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEG 130
E KE+ R+R ++ + ER KKE++ER++R +E+E +E EE+E+++++E++ER
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKERE-REREERERKRRREEEER------E 280
Query: 131 KERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190
KER R ER++ R ++ R KR R + E R+ + R R+ R
Sbjct: 281 KERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSR-----ERRRSRSRDRRRSRS 335
Query: 191 RNRKERK-KERERKERRERKKERKKKEERKKERQKDRQTNWREKE-RGKRERKERKK 245
+R ERK + R R RR + ++RK + R K R +++ +EKE RG ++K K
Sbjct: 336 HDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVK 392
Score = 85.1 bits (209), Expect = 5e-17
Identities = 62/217 (28%), Positives = 112/217 (51%), Gaps = 21/217 (9%)
Query: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
G + ++ E + ++ ++ K+ERE R +E++ E G G+ +
Sbjct: 147 GSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQS 206
Query: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
+ ++ G K K +E KE+ R E +R+ + +++++ER+ERE+
Sbjct: 207 RVDDHLMGKQHM----GYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREK--- 259
Query: 153 EREKERERKERKKRERKQVGEKEEERKEKER---KERKKRERNR-KERKKERERKERRER 208
ERE+ERE +ERK+R +EEE +EKER +ER+KR R+R + + +R+ R R
Sbjct: 260 EREREREERERKRR-------REEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSR 312
Query: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+R + ER++ R +DR+ R + + ERK R +
Sbjct: 313 DHKRSRSRERRRSRSRDRR---RSRSHDRSERKHRSR 346
Score = 81.3 bits (199), Expect = 7e-16
Identities = 46/170 (27%), Positives = 84/170 (49%), Gaps = 8/170 (4%)
Query: 39 REREREIETRK----EGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
RERERE RK E ++E+E R +ERR KR R R + R ++ + K
Sbjct: 261 REREREERERKRRREEEEREKERARDRERR---KRSRSRSRHSSRTSDRRCSRSRDHKRS 317
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
R R++RR ++ R +++ + R R + K R+RK + R + ++RE+ ++ +
Sbjct: 318 RSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377
Query: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKE 204
EKE+ + KK K G +E++ ++ + ++ +N E + E
Sbjct: 378 EKEKRGSDDKKSSVKS-GSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
Score = 64.7 bits (156), Expect = 7e-11
Identities = 34/117 (29%), Positives = 60/117 (51%), Gaps = 2/117 (1%)
Query: 24 HISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK 83
H S+ + +S +R R E R+ ++R R +R ER+ R R R++ R + R +
Sbjct: 299 HSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR 358
Query: 84 KEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGR--TSKEGKERERKEE 138
K K K +RE+ ++ +EKE + ++K+ K +E+ T+ E KE + K E
Sbjct: 359 KSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNE 415
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 109 bits (272), Expect = 2e-24
Identities = 65/186 (34%), Positives = 100/186 (53%), Gaps = 12/186 (6%)
Query: 56 ESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR----REKENKEGEE 111
E + K +R E + ER K+ K+ER ++EK+ ER++EERERK+RR REKE E
Sbjct: 229 ELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRE 288
Query: 112 KEKRKKKEKKERGRTSKE--GKERERKEERKREERKERERKKEEREKERERKERKKRERK 169
+ KR + + RTS + R+ K R RE R+ R R + R + +R ERK R R
Sbjct: 289 RRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDR-RRSRSHDRSERKHRSRS 347
Query: 170 QVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQ-T 228
+ + + R K K R K ++R+++R+ KE+ +R + KK + R+K + T
Sbjct: 348 RDRRRSKSRDRKSYKHRSK----SRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDT 403
Query: 229 NWREKE 234
N KE
Sbjct: 404 NTESKE 409
Score = 107 bits (267), Expect = 9e-24
Identities = 57/197 (28%), Positives = 108/197 (54%), Gaps = 11/197 (5%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
++ + E + ++ R E + +R+ KKE++ERE EREKER+RER ++E+K R++EE
Sbjct: 224 KATVEELKEKLRKRTE-EPDRDERLKKEKQERE----EREKEREREREERERKRRREEEE 278
Query: 95 RERKK---RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
RE+++ R R K ++ R + R R K + RER+ R R+ R+ R +
Sbjct: 279 REKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDR 338
Query: 152 EERE---KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
ER+ + R+R+ K R+RK + + R ++ ++ K++E+ + KK + RE+
Sbjct: 339 SERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREK 398
Query: 209 KKERKKKEERKKERQKD 225
+ E E ++ + + +
Sbjct: 399 QSEDTNTESKESDTKNE 415
Score = 100 bits (248), Expect = 2e-21
Identities = 61/208 (29%), Positives = 114/208 (54%), Gaps = 13/208 (6%)
Query: 38 IREREREIETRKEGKKERESERKKERREREKRK-REREKERKRERGKKEKKGERKKEERE 96
+ + + ++ GK+ + K E K K R+R +E R+ K++K ER++ E+E
Sbjct: 201 VGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKE 260
Query: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
R++ R E+E K E+E+R+K+ ++R R K + R R R + R R R +R +
Sbjct: 261 REREREERERKRRREEEEREKERARDRER-RKRSRSRSRHSSRTSDRRCSRSR-DHKRSR 318
Query: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNR-KERKKERERKERRERKKERKKK 215
RER+ + R+R++ + +R ERK R R+R + R K R+RK + R K R ++
Sbjct: 319 SRERRRSRSRDRRR-------SRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDRE 371
Query: 216 EERKKERQKDRQTNWREK--ERGKRERK 241
++RK + ++ R ++ ++ + G RE++
Sbjct: 372 QDRKSKEKEKRGSDDKKSSVKSGSREKQ 399
Score = 96.7 bits (239), Expect = 2e-20
Identities = 58/177 (32%), Positives = 98/177 (55%), Gaps = 15/177 (8%)
Query: 72 EREKERKRERGKKEKKGER-KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEG 130
E KE+ R+R ++ + ER KKE++ER++R +E+E +E EE+E+++++E++ER
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKERE-REREERERKRRREEEER------E 280
Query: 131 KERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190
KER R ER++ R ++ R KR R + E R+ + R R+ R
Sbjct: 281 KERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSR-----ERRRSRSRDRRRSRS 335
Query: 191 RNRKERK-KERERKERRERKKERKKKEERKKERQKDRQTNWREKE-RGKRERKERKK 245
+R ERK + R R RR + ++RK + R K R +++ +EKE RG ++K K
Sbjct: 336 HDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVK 392
Score = 85.1 bits (209), Expect = 5e-17
Identities = 62/217 (28%), Positives = 112/217 (51%), Gaps = 21/217 (9%)
Query: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
G + ++ E + ++ ++ K+ERE R +E++ E G G+ +
Sbjct: 147 GSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQS 206
Query: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
+ ++ G K K +E KE+ R E +R+ + +++++ER+ERE+
Sbjct: 207 RVDDHLMGKQHM----GYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREK--- 259
Query: 153 EREKERERKERKKRERKQVGEKEEERKEKER---KERKKRERNR-KERKKERERKERRER 208
ERE+ERE +ERK+R +EEE +EKER +ER+KR R+R + + +R+ R R
Sbjct: 260 EREREREERERKRR-------REEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSR 312
Query: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
+R + ER++ R +DR+ R + + ERK R +
Sbjct: 313 DHKRSRSRERRRSRSRDRR---RSRSHDRSERKHRSR 346
Score = 81.3 bits (199), Expect = 7e-16
Identities = 46/170 (27%), Positives = 84/170 (49%), Gaps = 8/170 (4%)
Query: 39 REREREIETRK----EGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
RERERE RK E ++E+E R +ERR KR R R + R ++ + K
Sbjct: 261 REREREERERKRRREEEEREKERARDRERR---KRSRSRSRHSSRTSDRRCSRSRDHKRS 317
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
R R++RR ++ R +++ + R R + K R+RK + R + ++RE+ ++ +
Sbjct: 318 RSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377
Query: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKE 204
EKE+ + KK K G +E++ ++ + ++ +N E + E
Sbjct: 378 EKEKRGSDDKKSSVKS-GSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
Score = 64.7 bits (156), Expect = 7e-11
Identities = 34/117 (29%), Positives = 60/117 (51%), Gaps = 2/117 (1%)
Query: 24 HISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK 83
H S+ + +S +R R E R+ ++R R +R ER+ R R R++ R + R +
Sbjct: 299 HSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR 358
Query: 84 KEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGR--TSKEGKERERKEE 138
K K K +RE+ ++ +EKE + ++K+ K +E+ T+ E KE + K E
Sbjct: 359 KSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNE 415
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 106 bits (264), Expect = 2e-23
Identities = 61/217 (28%), Positives = 121/217 (55%), Gaps = 14/217 (6%)
Query: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
RER+R+ + + K+R+ R ++RR R R R + + ER ++ K+ ER KE R+R
Sbjct: 28 RERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERERDKE-RDRN 86
Query: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER 158
K+ R+++ K+G ++K +K+ GR K+ K R+ ++ +K EE + ++K + +
Sbjct: 87 KKDRDRD-KDGHRRDKDRKRSSLSPGR-GKDFKSRKDRDSKKDEEDEHGDKKPKAQPLSL 144
Query: 159 ERKERKKRERKQVGEK----EEERKEKERKERKKRERNRKERKKERERKER-------RE 207
E KK+ ++ K + +E E +R+++E ++R E ERK+R R+
Sbjct: 145 EELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRK 204
Query: 208 RKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
++ +++E R++ + +R+TN E E G+++ +E K
Sbjct: 205 MLEDPQERERRERRERMERETNGNEDEEGRQKIREEK 241
Score = 104 bits (260), Expect = 6e-23
Identities = 71/232 (30%), Positives = 128/232 (55%), Gaps = 36/232 (15%)
Query: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKE----KKGERK 91
S+ R+R R + R+ G + R R K ERE+R +ERE++++R+R KK+ K G R+
Sbjct: 41 SKDRKRHRSRDRRRGGSRSRSRSRSKSA-ERERRHKERERDKERDRNKKDRDRDKDGHRR 99
Query: 92 KEERERK----------KRRREKENKEGEEKEKRKKKEK-----------KERGRTSKEG 130
++R+R K R+++++K+ EE E KK K K++ E
Sbjct: 100 DKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEA 159
Query: 131 KERE-RKEERKREERKERERKKEEREKERERKERKKRERKQVGEK----EEERKEKERKE 185
K + K ER+ E K R+++ EER++ E + +K+++ + +G K +ER+ +ER+E
Sbjct: 160 KPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRE 219
Query: 186 RKKRERNRKERKKERER-KERRERKKERKKKEERK----KERQKDRQTNWRE 232
R +RE N E ++ R++ +E +++ KE +ER K+R++ R N R+
Sbjct: 220 RMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRK 271
Score = 78.2 bits (191), Expect = 6e-15
Identities = 54/190 (28%), Positives = 95/190 (50%), Gaps = 22/190 (11%)
Query: 78 KRERGKKEKKGERKKEERERKKRRREKENKEGEEKE-KRKKKEKKERGRTSKEGKERERK 136
K++R K ERK+ ++R R+++ K K+ KR + + RG + + R +
Sbjct: 8 KKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKS 67
Query: 137 EER-----KREERKERERKKEEREKE----RERKERKK-----------RERKQVGEKEE 176
ER +RE KER+R K++R+++ R K+RK+ + RK K++
Sbjct: 68 AERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKD 127
Query: 177 ERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERG 236
E E K+ K + + +E +++ +E E K + K ER+ E K RQ E++R
Sbjct: 128 EEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRM 187
Query: 237 -KRERKERKK 245
+ ERK+RK+
Sbjct: 188 LEEERKKRKQ 197
Score = 70.9 bits (172), Expect = 1e-12
Identities = 41/135 (30%), Positives = 73/135 (54%), Gaps = 6/135 (4%)
Query: 110 EEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERK 169
++K++ K+ER R+ +ER+R +RK K+R+R R ++R R + R R
Sbjct: 7 DKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKR---HRSRDRRRGGSRSRSRS 63
Query: 170 QVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKE--RQKDRQ 227
+ E ER+ KER+ K+R+RN+K+R ++++ R + +K R K+ +KDR
Sbjct: 64 RSKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRD 123
Query: 228 TNW-REKERGKRERK 241
+ E E G ++ K
Sbjct: 124 SKKDEEDEHGDKKPK 138
Score = 69.7 bits (169), Expect = 2e-12
Identities = 64/236 (27%), Positives = 113/236 (47%), Gaps = 43/236 (18%)
Query: 27 KPCTQPGWQSEI-----REREREIETRKEGKKERESERKKERRER-EKRKREREKERKRE 80
KP QP E+ E E E + + K ERE+E K R++ E+R+R E+ERK+
Sbjct: 136 KPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKR 195
Query: 81 R-----GKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER 135
+ G+K + +++E RER++R + N +E+ ++K +E+K++ + KER
Sbjct: 196 KQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYL 255
Query: 136 KEERKREERKERERKKEERE---------------KERER--------------KERKKR 166
+KR + +K E KER + K++K+
Sbjct: 256 GGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKRE 315
Query: 167 ERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKER 222
+ + G+ E+R+ E KE+++ R RK RKK E K+R + + +KK + +R
Sbjct: 316 QSRFYGDLMEKRRTLEEKEQEEA-RLRKLRKK--EAKQRWDDRHWSQKKLDEMTDR 368
Score = 67.0 bits (162), Expect = 1e-11
Identities = 54/222 (24%), Positives = 119/222 (53%), Gaps = 26/222 (11%)
Query: 44 EIETRKEGKKERESERK---KERREREKRKREREKERKRERGKKEKKGERKKEERERKKR 100
E+ +K+ ++E E++ K K RE E KR +++ +R+R +E++ +K+++ + R
Sbjct: 146 ELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEER--KKRKQFQDLGR 203
Query: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERER 160
+ ++ +E E +E+R++ E++ G +EG+++ R+E+ K +E + + K+R R
Sbjct: 204 KMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKR-R 262
Query: 161 KERKKRERKQVGEKEEERKE--------KERKERKKRER------NRKERKKERER---- 202
+ R +RK V E + KER + + R + K++K+E+ R
Sbjct: 263 RTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKREQSRFYGD 322
Query: 203 -KERRERKKERKKKEER-KKERQKDRQTNWREKERGKRERKE 242
E+R +E++++E R +K R+K+ + W ++ +++ E
Sbjct: 323 LMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDE 364
Score = 58.2 bits (139), Expect = 7e-09
Identities = 31/103 (30%), Positives = 59/103 (57%), Gaps = 4/103 (3%)
Query: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR 193
E +++ R+ +E +K R +RER + R+RK K+ +R + R R+ R+R
Sbjct: 4 ELADKKDRDASPSKEERKRSRTPDRERD--RDRDRKSSPSKDRKR-HRSRDRRRGGSRSR 60
Query: 194 KERKKERERKERRERKKERKKKEER-KKERQKDRQTNWREKER 235
+ + +ERR +++ER K+ +R KK+R +D+ + R+K+R
Sbjct: 61 SRSRSKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDR 103
Score = 57.4 bits (137), Expect = 1e-08
Identities = 29/103 (28%), Positives = 56/103 (54%), Gaps = 4/103 (3%)
Query: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
++K+R+ + E++R R ++R+R + + + K + R +R + R + R +
Sbjct: 7 DKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSK 66
Query: 203 KERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
RER R K+ ER KER ++++ R+K+ G R K+RK+
Sbjct: 67 SAERER---RHKERERDKERDRNKKDRDRDKD-GHRRDKDRKR 105
Score = 40.0 bits (92), Expect = 0.002
Identities = 44/209 (21%), Positives = 81/209 (38%), Gaps = 73/209 (34%)
Query: 35 QSEIREREREIETRKEGKK--------------ERESERKKERREREKRKREREKERKRE 80
Q E+ ER+R +E ++ +K ERE ++ER ERE E E+ R++
Sbjct: 178 QQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKI 237
Query: 81 RGKKEKKGER-----------KKEERER-------------------------------- 97
R +K+K E KK R R
Sbjct: 238 REEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQ 297
Query: 98 ------------KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
K+++RE+ G+ EKR+ E+KE+ +E + R+ +++ ++
Sbjct: 298 LLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQ----EEARLRKLRKKEAKQRWD 353
Query: 146 ERERKKEEREKERERKERKKRERKQVGEK 174
+R +++ ++ +R R RE + K
Sbjct: 354 DRHWSQKKLDEMTDRDWRIFREDYSITTK 382
Score = 29.6 bits (65), Expect = 2.5
Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 12/80 (15%)
Query: 60 KKERRER--------EKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE 111
K+++RE+ EKR+ EKE++ R +K RKKE ++R R + K E
Sbjct: 310 KQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKL----RKKEAKQRWDDRHWSQKKLDEM 365
Query: 112 KEKRKKKEKKERGRTSKEGK 131
++ + +++ T+K GK
Sbjct: 366 TDRDWRIFREDYSITTKGGK 385
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 104 bits (259), Expect = 8e-23
Identities = 65/217 (29%), Positives = 134/217 (61%), Gaps = 13/217 (5%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E + +E+E + ++ K RE E K R+E EK + EK R++E +K ++++
Sbjct: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMWRQE-EKMHEQEEKIREQE----DKMWRQEEK 354
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKK--ERGRTSKEGKERERKEERKREERKERERKK 151
RE++++ RE+E K ++EK +++++K E+ +E+ R++E KR+E+ R+ KK
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK 414
Query: 152 --EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERK 209
E+ EK RE++E R+ +++ E EE +++E K R+ E+ ++E +K +E++E+ +R+
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 210 KERKKKEERKKERQ----KDRQTNWREKERGKRERKE 242
+E+ +++E K RQ K + W ++E+ R+ ++
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEK 511
Score = 100 bits (249), Expect = 1e-21
Identities = 74/246 (30%), Positives = 144/246 (58%), Gaps = 26/246 (10%)
Query: 10 AVKLNTELQMVSCSHISKPCTQPGWQSEIRERE--REIETRKEGKKERESERKKERRER- 66
A +L ELQ VS Q+++ E E + ++E K R+ E+ +E+ E+
Sbjct: 264 ADRLGKELQSVSAK----------LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKM 313
Query: 67 ---EKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK--EKRKKKEKK 121
E + RE+E++ R+ K ++ E K E+E K R+E++ +E EEK E+ +K ++
Sbjct: 314 CEQELKIREQEEKMWRQEEKMHEQ-EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQ 372
Query: 122 ERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRER-KQVGEKEEERKE 180
E ++ K +E++EE R+E K RE ++E+R+++ R+E+K RE+ +++ E+EEE
Sbjct: 373 EEKIREQDEKIQEQEEEMWRQEEKIRE-QEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 181 KERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR-----QTNWREKER 235
+E K R+ E + + +K RE +E+ + ++E+ +++E K +RQ+++ + WR+++
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 236 GKRERK 241
K+E K
Sbjct: 492 LKQEEK 497
Score = 98.6 bits (244), Expect = 4e-21
Identities = 61/226 (26%), Positives = 138/226 (61%), Gaps = 16/226 (7%)
Query: 34 WQSEIREREREIETRK-EGKKERESERKKERREREKRKRE---REKERKRERGKKEKKGE 89
W+ E + E+E + R+ E K R+ E+ +E+ E+ + + E R++E+ RE+ +K ++ E
Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
Query: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE------ 143
+ +E K R +E++ +E ++++K +E+ E+ R +E R+ ++ R+ EE
Sbjct: 388 EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE 447
Query: 144 ---RKERERKKEEREKERERKERKKRERKQVGEKEEE--RKEKERKERKK-RERNRKERK 197
R+ E+ +EE EK +E++E+ +R+ +++ E+EE+ R+EK K+ +K E+ K +
Sbjct: 448 EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507
Query: 198 KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
+E + E+ E+ +E+++K +R++E+ ++++ ++E +E++ R
Sbjct: 508 QEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Score = 94.7 bits (234), Expect = 6e-20
Identities = 59/218 (27%), Positives = 141/218 (64%), Gaps = 14/218 (6%)
Query: 34 WQSEIREREREIETRKEGKKE-RESERKKERRER-----EKRKREREKERKRERGKKEKK 87
W+ E + RE+E + R++ +K R+ E+ +E+ E+ E+ R+ EK R++E ++EK
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKM 408
Query: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSK--EGKERERKEERKREERK 145
++K+ RE+ ++ RE+E + ++EK ++ E+ + + K E +E+ ++EE K +E++
Sbjct: 409 WRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468
Query: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER 205
E+ +++EE+ +E+E K + ++++ ++EE+ E+E K ++ E+ ++ +K +E++E+
Sbjct: 469 EKIQRQEEKIQEQEEKTWR---QEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEK 525
Query: 206 RERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
+R++E+ +++E + +Q+++ +E+E +E +ER
Sbjct: 526 MQRQEEKMREQEVRLWQQEEKM---QEQEVRLQELEER 560
Score = 94.0 bits (232), Expect = 1e-19
Identities = 57/217 (26%), Positives = 131/217 (60%), Gaps = 7/217 (3%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERRE-----REKRKREREKERKRERGKKEKKGE 89
+ E++ RE+E + ++ +K E E K +E +E++ RE+E E+ RE+ +K + E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEEKMWRQE 373
Query: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKER-GRTSKEGKERERKEERKREERKERE 148
K E++ K + +E+E EEK + ++++++E+ R K+ +E++ K + EE +E
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
K E E+ + +E K RE ++ ++EEE+ +++ ++ +++E +E++++ R+E+ +
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
++E+ ++E K RQ+++ EK + + E+ +R++
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQE 530
Score = 91.7 bits (226), Expect = 5e-19
Identities = 65/243 (26%), Positives = 140/243 (57%), Gaps = 9/243 (3%)
Query: 6 SSRAAVKLNTE--LQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKER 63
S ++ ++LN + + + + + P Q +++ +E + + K + E+E
Sbjct: 232 SEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLL 291
Query: 64 REREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK--EKRKKKEKK 121
++++ K R++E+ +E+ +K + E K E+E K R+E++ E EEK E+ K ++
Sbjct: 292 NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQ 351
Query: 122 ERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEK 181
E +E K RE++E+ R+E K R E+ EK +E++E R+ +++ E+EE+R+EK
Sbjct: 352 EEKIREQEEKIREQEEKMWRQEEKIR----EQDEKIQEQEEEMWRQEEKIREQEEKRQEK 407
Query: 182 E-RKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRER 240
R+E+K RE++ K R++E E + E+ +E ++ + ++E+ ++ + +E+E +E+
Sbjct: 408 MWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQ 467
Query: 241 KER 243
+E+
Sbjct: 468 EEK 470
Score = 85.9 bits (211), Expect = 3e-17
Identities = 52/187 (27%), Positives = 117/187 (62%), Gaps = 4/187 (2%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+ E+ +E +I ++E ++E+ ++K+ RE++++ RE+E+E R+ +EK E ++
Sbjct: 387 EEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQ---EEKIRELEEMM 443
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
++++++ RE E K EE+EK +++E+K + R ++ +E+E K R+ + K+ E+ E+
Sbjct: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQ-RQEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502
Query: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
EK ++E+ + +++ E+EE+ + +E K R++ R ++ +K +E++ R + +ER
Sbjct: 503 EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLG 562
Query: 215 KEERKKE 221
K +K E
Sbjct: 563 KLGQKAE 569
Score = 80.9 bits (198), Expect = 9e-16
Identities = 62/223 (27%), Positives = 129/223 (57%), Gaps = 19/223 (8%)
Query: 36 SEIREREREIETRKEGKK--ERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
+E++E+ R +E+ K + ++ +RK ER + +++ + E R GK+ + K +
Sbjct: 221 AELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADR-LGKELQSVSAKLQ 279
Query: 94 ERERKKRRREKENKEGEEK--EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
+ + N++ EEK + +K +++E +E K RE++E+ R+E E+
Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE----EKMH 335
Query: 152 EEREKERERKERKKRERKQVGEKEEERKEKE----RKERKKRERNRKERKKERE--RKER 205
E+ EK RE++++ R+ +++ E+EE+ +E+E R+E K RE++ K +++E E R+E
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEE 395
Query: 206 RERKKERKKKE----ERKKERQKDRQTNWREKERGKRERKERK 244
+ R++E K++E + KK R++D + +E+E ++E K R+
Sbjct: 396 KIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRE 438
Score = 65.1 bits (157), Expect = 5e-11
Identities = 46/191 (24%), Positives = 100/191 (52%), Gaps = 12/191 (6%)
Query: 66 REKRKREREKERKRERGKKE----KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK 121
+EK +EK R E K E K ++K ER + +++ E + K +
Sbjct: 217 KEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSA 276
Query: 122 ERGRTSKEGKERERKEERKREERKERERKKEERE--------KERERKERKKRERKQVGE 173
+ +E + +++ E+ +E K +E+E K RE++E+ R+ +++ E
Sbjct: 277 KLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHE 336
Query: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREK 233
+EE+ +E+E K ++ E+ R++ +K RE++E+ R++E+ ++++ K + Q++ EK
Sbjct: 337 QEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396
Query: 234 ERGKRERKERK 244
R + E+++ K
Sbjct: 397 IREQEEKRQEK 407
Score = 54.3 bits (129), Expect = 9e-08
Identities = 51/209 (24%), Positives = 105/209 (50%), Gaps = 35/209 (16%)
Query: 50 EGKKERESERKKERREREKRKRE-----REKERKRERGKKEKKGERKKEERERKKRRREK 104
E KE+ +E +++ R E K E ++ +RK ER + ++ + E +R
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRL------ 267
Query: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE-KERERKER 163
KE + + + + +E + +++E K R+ E+ +E+E K E+E K RE++E+
Sbjct: 268 -GKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEK 326
Query: 164 KKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKE-- 221
R+ +++ E+EE+ +E+E K R+E + R++E K +E+ +K
Sbjct: 327 MWRQEEKMHEQEEKIREQEDK---------------MWRQEEKIREQEEKIREQEEKMWR 371
Query: 222 -----RQKDRQTNWREKERGKRERKERKK 245
R++D + +E+E ++E K R++
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQ 400
Score = 33.5 bits (75), Expect = 0.17
Identities = 41/189 (21%), Positives = 77/189 (40%), Gaps = 4/189 (2%)
Query: 60 KKERREREKRK---REREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRK 116
K E++ + + K + REK E+ + + E E R+R+ +R E+ + EE E K
Sbjct: 38 KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSK 97
Query: 117 K-KEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKE 175
+ KE +R + E ++ E K ++++ + E+ RK+V K+
Sbjct: 98 QCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKK 157
Query: 176 EERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKER 235
+ E +K+ E + E + R E+ KE + R T E+ +
Sbjct: 158 PWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELK 217
Query: 236 GKRERKERK 244
K + K
Sbjct: 218 EKNAELQEK 226
Score = 30.8 bits (68), Expect = 1.1
Identities = 24/108 (22%), Positives = 55/108 (50%), Gaps = 9/108 (8%)
Query: 35 QSEIRERE----REIETRKEGKKERESERKKERRE-----REKRKREREKERKRERGKKE 85
+ +I+E+E R+ + K+ +K E E K R+E +E++ +E+E++ +R+ K
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMR 534
Query: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
++ R ++ E+ + + + + E K +K + G + G +R
Sbjct: 535 EQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQR 582
Score = 30.4 bits (67), Expect = 1.5
Identities = 28/121 (23%), Positives = 52/121 (42%), Gaps = 1/121 (0%)
Query: 125 RTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERK 184
+ ++ K R + + RE+ E+ + E E + RK+R K+ E ++ + ++ K
Sbjct: 38 KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSK 97
Query: 185 ERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
+ K+ + + E E +K +E K +K RQ EK R+R K
Sbjct: 98 QCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKK-RQEKMNEKNYTFRKRVVIK 156
Query: 245 K 245
K
Sbjct: 157 K 157
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 104 bits (259), Expect = 8e-23
Identities = 65/217 (29%), Positives = 134/217 (61%), Gaps = 13/217 (5%)
Query: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
W+ E + +E+E + ++ K RE E K R+E EK + EK R++E +K ++++
Sbjct: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMWRQE-EKMHEQEEKIREQE----DKMWRQEEK 354
Query: 94 ERERKKRRREKENKEGEEKEKRKKKEKK--ERGRTSKEGKERERKEERKREERKERERKK 151
RE++++ RE+E K ++EK +++++K E+ +E+ R++E KR+E+ R+ KK
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK 414
Query: 152 --EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERK 209
E+ EK RE++E R+ +++ E EE +++E K R+ E+ ++E +K +E++E+ +R+
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 210 KERKKKEERKKERQ----KDRQTNWREKERGKRERKE 242
+E+ +++E K RQ K + W ++E+ R+ ++
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEK 511
Score = 100 bits (249), Expect = 1e-21
Identities = 74/246 (30%), Positives = 144/246 (58%), Gaps = 26/246 (10%)
Query: 10 AVKLNTELQMVSCSHISKPCTQPGWQSEIRERE--REIETRKEGKKERESERKKERRER- 66
A +L ELQ VS Q+++ E E + ++E K R+ E+ +E+ E+
Sbjct: 264 ADRLGKELQSVSAK----------LQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKM 313
Query: 67 ---EKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK--EKRKKKEKK 121
E + RE+E++ R+ K ++ E K E+E K R+E++ +E EEK E+ +K ++
Sbjct: 314 CEQELKIREQEEKMWRQEEKMHEQ-EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQ 372
Query: 122 ERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRER-KQVGEKEEERKE 180
E ++ K +E++EE R+E K RE ++E+R+++ R+E+K RE+ +++ E+EEE
Sbjct: 373 EEKIREQDEKIQEQEEEMWRQEEKIRE-QEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 181 KERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR-----QTNWREKER 235
+E K R+ E + + +K RE +E+ + ++E+ +++E K +RQ+++ + WR+++
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491
Query: 236 GKRERK 241
K+E K
Sbjct: 492 LKQEEK 497
Score = 98.6 bits (244), Expect = 4e-21
Identities = 61/226 (26%), Positives = 138/226 (61%), Gaps = 16/226 (7%)
Query: 34 WQSEIREREREIETRK-EGKKERESERKKERREREKRKRE---REKERKRERGKKEKKGE 89
W+ E + E+E + R+ E K R+ E+ +E+ E+ + + E R++E+ RE+ +K ++ E
Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
Query: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE------ 143
+ +E K R +E++ +E ++++K +E+ E+ R +E R+ ++ R+ EE
Sbjct: 388 EEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE 447
Query: 144 ---RKERERKKEEREKERERKERKKRERKQVGEKEEE--RKEKERKERKK-RERNRKERK 197
R+ E+ +EE EK +E++E+ +R+ +++ E+EE+ R+EK K+ +K E+ K +
Sbjct: 448 EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507
Query: 198 KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
+E + E+ E+ +E+++K +R++E+ ++++ ++E +E++ R
Sbjct: 508 QEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Score = 94.7 bits (234), Expect = 6e-20
Identities = 59/218 (27%), Positives = 141/218 (64%), Gaps = 14/218 (6%)
Query: 34 WQSEIREREREIETRKEGKKE-RESERKKERRER-----EKRKREREKERKRERGKKEKK 87
W+ E + RE+E + R++ +K R+ E+ +E+ E+ E+ R+ EK R++E ++EK
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKM 408
Query: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSK--EGKERERKEERKREERK 145
++K+ RE+ ++ RE+E + ++EK ++ E+ + + K E +E+ ++EE K +E++
Sbjct: 409 WRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468
Query: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER 205
E+ +++EE+ +E+E K + ++++ ++EE+ E+E K ++ E+ ++ +K +E++E+
Sbjct: 469 EKIQRQEEKIQEQEEKTWR---QEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEK 525
Query: 206 RERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243
+R++E+ +++E + +Q+++ +E+E +E +ER
Sbjct: 526 MQRQEEKMREQEVRLWQQEEKM---QEQEVRLQELEER 560
Score = 94.0 bits (232), Expect = 1e-19
Identities = 57/217 (26%), Positives = 131/217 (60%), Gaps = 7/217 (3%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERRE-----REKRKREREKERKRERGKKEKKGE 89
+ E++ RE+E + ++ +K E E K +E +E++ RE+E E+ RE+ +K + E
Sbjct: 315 EQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEEKMWRQE 373
Query: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKER-GRTSKEGKERERKEERKREERKERE 148
K E++ K + +E+E EEK + ++++++E+ R K+ +E++ K + EE +E
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
K E E+ + +E K RE ++ ++EEE+ +++ ++ +++E +E++++ R+E+ +
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
++E+ ++E K RQ+++ EK + + E+ +R++
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQE 530
Score = 91.7 bits (226), Expect = 5e-19
Identities = 65/243 (26%), Positives = 140/243 (57%), Gaps = 9/243 (3%)
Query: 6 SSRAAVKLNTE--LQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKER 63
S ++ ++LN + + + + + P Q +++ +E + + K + E+E
Sbjct: 232 SEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLL 291
Query: 64 REREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK--EKRKKKEKK 121
++++ K R++E+ +E+ +K + E K E+E K R+E++ E EEK E+ K ++
Sbjct: 292 NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQ 351
Query: 122 ERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEK 181
E +E K RE++E+ R+E K R E+ EK +E++E R+ +++ E+EE+R+EK
Sbjct: 352 EEKIREQEEKIREQEEKMWRQEEKIR----EQDEKIQEQEEEMWRQEEKIREQEEKRQEK 407
Query: 182 E-RKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRER 240
R+E+K RE++ K R++E E + E+ +E ++ + ++E+ ++ + +E+E +E+
Sbjct: 408 MWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQ 467
Query: 241 KER 243
+E+
Sbjct: 468 EEK 470
Score = 85.9 bits (211), Expect = 3e-17
Identities = 52/187 (27%), Positives = 117/187 (62%), Gaps = 4/187 (2%)
Query: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
+ E+ +E +I ++E ++E+ ++K+ RE++++ RE+E+E R+ +EK E ++
Sbjct: 387 EEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQ---EEKIRELEEMM 443
Query: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
++++++ RE E K EE+EK +++E+K + R ++ +E+E K R+ + K+ E+ E+
Sbjct: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQ-RQEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502
Query: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
EK ++E+ + +++ E+EE+ + +E K R++ R ++ +K +E++ R + +ER
Sbjct: 503 EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLG 562
Query: 215 KEERKKE 221
K +K E
Sbjct: 563 KLGQKAE 569
Score = 80.9 bits (198), Expect = 9e-16
Identities = 62/223 (27%), Positives = 129/223 (57%), Gaps = 19/223 (8%)
Query: 36 SEIREREREIETRKEGKK--ERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93
+E++E+ R +E+ K + ++ +RK ER + +++ + E R GK+ + K +
Sbjct: 221 AELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADR-LGKELQSVSAKLQ 279
Query: 94 ERERKKRRREKENKEGEEK--EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
+ + N++ EEK + +K +++E +E K RE++E+ R+E E+
Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE----EKMH 335
Query: 152 EEREKERERKERKKRERKQVGEKEEERKEKE----RKERKKRERNRKERKKERE--RKER 205
E+ EK RE++++ R+ +++ E+EE+ +E+E R+E K RE++ K +++E E R+E
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEE 395
Query: 206 RERKKERKKKE----ERKKERQKDRQTNWREKERGKRERKERK 244
+ R++E K++E + KK R++D + +E+E ++E K R+
Sbjct: 396 KIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRE 438
Score = 65.1 bits (157), Expect = 5e-11
Identities = 46/191 (24%), Positives = 100/191 (52%), Gaps = 12/191 (6%)
Query: 66 REKRKREREKERKRERGKKE----KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK 121
+EK +EK R E K E K ++K ER + +++ E + K +
Sbjct: 217 KEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSA 276
Query: 122 ERGRTSKEGKERERKEERKREERKERERKKEERE--------KERERKERKKRERKQVGE 173
+ +E + +++ E+ +E K +E+E K RE++E+ R+ +++ E
Sbjct: 277 KLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHE 336
Query: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREK 233
+EE+ +E+E K ++ E+ R++ +K RE++E+ R++E+ ++++ K + Q++ EK
Sbjct: 337 QEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396
Query: 234 ERGKRERKERK 244
R + E+++ K
Sbjct: 397 IREQEEKRQEK 407
Score = 54.3 bits (129), Expect = 9e-08
Identities = 51/209 (24%), Positives = 105/209 (50%), Gaps = 35/209 (16%)
Query: 50 EGKKERESERKKERREREKRKRE-----REKERKRERGKKEKKGERKKEERERKKRRREK 104
E KE+ +E +++ R E K E ++ +RK ER + ++ + E +R
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRL------ 267
Query: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE-KERERKER 163
KE + + + + +E + +++E K R+ E+ +E+E K E+E K RE++E+
Sbjct: 268 -GKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEK 326
Query: 164 KKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKE-- 221
R+ +++ E+EE+ +E+E K R+E + R++E K +E+ +K
Sbjct: 327 MWRQEEKMHEQEEKIREQEDK---------------MWRQEEKIREQEEKIREQEEKMWR 371
Query: 222 -----RQKDRQTNWREKERGKRERKERKK 245
R++D + +E+E ++E K R++
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQ 400
Score = 33.1 bits (74), Expect = 0.23
Identities = 41/189 (21%), Positives = 77/189 (40%), Gaps = 4/189 (2%)
Query: 60 KKERREREKRK---REREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRK 116
K E++ + + K + REK E+ + + E E R+R+ +R E+ + EE E K
Sbjct: 38 KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSK 97
Query: 117 K-KEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKE 175
+ KE +R + E ++ E K ++++ + E+ RK+V K+
Sbjct: 98 QCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKK 157
Query: 176 EERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKER 235
+ E +K+ E + E + R E+ KE + R T E+ +
Sbjct: 158 PWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELK 217
Query: 236 GKRERKERK 244
K + K
Sbjct: 218 EKNAELQEK 226
Score = 30.8 bits (68), Expect = 1.1
Identities = 24/108 (22%), Positives = 55/108 (50%), Gaps = 9/108 (8%)
Query: 35 QSEIRERE----REIETRKEGKKERESERKKERRE-----REKRKREREKERKRERGKKE 85
+ +I+E+E R+ + K+ +K E E K R+E +E++ +E+E++ +R+ K
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMR 534
Query: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
++ R ++ E+ + + + + E K +K + G + G +R
Sbjct: 535 EQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQR 582
Score = 30.4 bits (67), Expect = 1.5
Identities = 28/121 (23%), Positives = 52/121 (42%), Gaps = 1/121 (0%)
Query: 125 RTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERK 184
+ ++ K R + + RE+ E+ + E E + RK+R K+ E ++ + ++ K
Sbjct: 38 KLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSK 97
Query: 185 ERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
+ K+ + + E E +K +E K +K RQ EK R+R K
Sbjct: 98 QCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKK-RQEKMNEKNYTFRKRVVIK 156
Query: 245 K 245
K
Sbjct: 157 K 157
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.300 0.120 0.304
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,964,753
Number of Sequences: 37866
Number of extensions: 812633
Number of successful extensions: 175819
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2657
Number of HSP's successfully gapped in prelim test: 780
Number of HSP's that attempted gapping in prelim test: 9388
Number of HSP's gapped (non-prelim): 52753
length of query: 245
length of database: 18,247,518
effective HSP length: 100
effective length of query: 145
effective length of database: 14,460,918
effective search space: 2096833110
effective search space used: 2096833110
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.