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Search of human proteins with 239754777
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239754777 PREDICTED: hypothetical protein [Homo sapiens]
(242 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239754777 PREDICTED: hypothetical protein [Homo sapiens] 509 e-144
gi|239749305 PREDICTED: hypothetical protein XP_002346991 [Homo ... 509 e-144
gi|239743399 PREDICTED: hypothetical protein XP_002342839 [Homo ... 509 e-144
gi|239509098 PREDICTED: hypothetical protein [Homo sapiens] 509 e-144
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 49 5e-06
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 46 3e-05
gi|60097902 filaggrin [Homo sapiens] 46 3e-05
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 44 1e-04
gi|166795264 AE binding protein 2 isoform b [Homo sapiens] 43 3e-04
gi|166795262 AE binding protein 2 isoform a [Homo sapiens] 43 3e-04
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 41 8e-04
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 40 0.001
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 40 0.001
gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b ... 40 0.002
gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a ... 40 0.002
gi|15721939 metastatic lymph node 51 [Homo sapiens] 40 0.002
gi|190194423 SPARC-like 1 [Homo sapiens] 39 0.003
gi|190341024 SPARC-like 1 [Homo sapiens] 39 0.003
gi|57864582 hornerin [Homo sapiens] 38 0.009
gi|217330641 IWS1 homolog [Homo sapiens] 36 0.034
gi|239756943 PREDICTED: hypothetical protein [Homo sapiens] 35 0.045
gi|239751443 PREDICTED: hypothetical protein [Homo sapiens] 35 0.045
gi|239745948 PREDICTED: hypothetical protein XP_002343622 [Homo ... 35 0.045
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 35 0.059
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 35 0.059
gi|27894378 chloride intracellular channel 6 [Homo sapiens] 35 0.059
gi|221316599 chromogranin B precursor [Homo sapiens] 35 0.077
gi|194272200 actin binding LIM protein family, member 2 isoform ... 35 0.077
gi|194272198 actin binding LIM protein family, member 2 isoform ... 35 0.077
gi|54607124 RNA binding motif protein 15B [Homo sapiens] 34 0.13
>gi|239754777 PREDICTED: hypothetical protein [Homo sapiens]
Length = 242
Score = 509 bits (1310), Expect = e-144
Identities = 242/242 (100%), Positives = 242/242 (100%)
Query: 1 MGISLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFH 60
MGISLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFH
Sbjct: 1 MGISLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFH 60
Query: 61 LSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGD 120
LSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGD
Sbjct: 61 LSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGD 120
Query: 121 RCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDD 180
RCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDD
Sbjct: 121 RCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDD 180
Query: 181 EPESGRGAAEAQAGLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTWAPSPY 240
EPESGRGAAEAQAGLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTWAPSPY
Sbjct: 181 EPESGRGAAEAQAGLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTWAPSPY 240
Query: 241 RP 242
RP
Sbjct: 241 RP 242
>gi|239749305 PREDICTED: hypothetical protein XP_002346991 [Homo
sapiens]
Length = 242
Score = 509 bits (1310), Expect = e-144
Identities = 242/242 (100%), Positives = 242/242 (100%)
Query: 1 MGISLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFH 60
MGISLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFH
Sbjct: 1 MGISLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFH 60
Query: 61 LSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGD 120
LSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGD
Sbjct: 61 LSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGD 120
Query: 121 RCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDD 180
RCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDD
Sbjct: 121 RCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDD 180
Query: 181 EPESGRGAAEAQAGLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTWAPSPY 240
EPESGRGAAEAQAGLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTWAPSPY
Sbjct: 181 EPESGRGAAEAQAGLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTWAPSPY 240
Query: 241 RP 242
RP
Sbjct: 241 RP 242
>gi|239743399 PREDICTED: hypothetical protein XP_002342839 [Homo
sapiens]
Length = 242
Score = 509 bits (1310), Expect = e-144
Identities = 242/242 (100%), Positives = 242/242 (100%)
Query: 1 MGISLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFH 60
MGISLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFH
Sbjct: 1 MGISLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFH 60
Query: 61 LSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGD 120
LSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGD
Sbjct: 61 LSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGD 120
Query: 121 RCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDD 180
RCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDD
Sbjct: 121 RCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDD 180
Query: 181 EPESGRGAAEAQAGLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTWAPSPY 240
EPESGRGAAEAQAGLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTWAPSPY
Sbjct: 181 EPESGRGAAEAQAGLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTWAPSPY 240
Query: 241 RP 242
RP
Sbjct: 241 RP 242
>gi|239509098 PREDICTED: hypothetical protein [Homo sapiens]
Length = 242
Score = 509 bits (1310), Expect = e-144
Identities = 242/242 (100%), Positives = 242/242 (100%)
Query: 1 MGISLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFH 60
MGISLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFH
Sbjct: 1 MGISLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFH 60
Query: 61 LSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGD 120
LSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGD
Sbjct: 61 LSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGD 120
Query: 121 RCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDD 180
RCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDD
Sbjct: 121 RCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDD 180
Query: 181 EPESGRGAAEAQAGLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTWAPSPY 240
EPESGRGAAEAQAGLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTWAPSPY
Sbjct: 181 EPESGRGAAEAQAGLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTWAPSPY 240
Query: 241 RP 242
RP
Sbjct: 241 RP 242
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 48.5 bits (114), Expect = 5e-06
Identities = 49/201 (24%), Positives = 76/201 (37%), Gaps = 46/201 (22%)
Query: 28 GGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQ- 86
G G +EG+ G G +EE GE +G GE GE E E+E EGEG+
Sbjct: 865 GEGEEEGEEG---EGEGEEEE-GEGEGE------EEGEGEGEEEEGEGEGEEEGEGEGEE 914
Query: 87 ------GGSCGHDGPEQGQAEQLQG-------------------REQVHTEGPDLGGGDR 121
G G +G +G+ E+ +G E+ EG + G G+
Sbjct: 915 EEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEG 974
Query: 122 CHSLAHDSERVGVSDRADSGSSQPGQAK-EGTDAAHGHDEQQVQVEAGALLQHALLLGDD 180
E G + + + G+ + EG + G E++ + E + G+
Sbjct: 975 EEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGE---------VEGEV 1025
Query: 181 EPESGRGAAEAQAGLSSADHR 201
E E G G E + G + R
Sbjct: 1026 EGEEGEGEGEEEEGEEEGEER 1046
Score = 45.4 bits (106), Expect = 4e-05
Identities = 45/170 (26%), Positives = 68/170 (40%), Gaps = 31/170 (18%)
Query: 29 GGGQEGKWGGLSRSTG-RQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQG 87
GG EG G + G R+EE E +G E+ GE E E+E EGEG+G
Sbjct: 811 GGEVEG--GEVEEGKGEREEEEEEGEGE---------EEEGEGEEEEGEGEEE-EGEGKG 858
Query: 88 GSCGHDGPEQGQAEQLQG---REQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQ 144
G +G + + E+ +G E+ EG + G G+ + E G + G +
Sbjct: 859 EEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE---GEEEEGEGEGEEEGEGEGEEE 915
Query: 145 PGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEPESGRGAAEAQAG 194
G+ K + G E + + G+ E E G G E + G
Sbjct: 916 EGEGKGEEEGEEGEGEGEEEE------------GEGEGEDGEGEGEEEEG 953
Score = 42.7 bits (99), Expect = 3e-04
Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 5/154 (3%)
Query: 45 RQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQ 104
++ E G R E+ GE E E+E+E EG+G G +G+ E+ +
Sbjct: 713 KEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEE 772
Query: 105 G-REQVHTEGPDLGG---GDRCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDE 160
G R++ G + G GD+ ++E G ++ + G + G+ +EG +E
Sbjct: 773 GERKKEERAGKEEKGEEEGDQGEGEEEETEGRG-EEKEEGGEVEGGEVEEGKGEREEEEE 831
Query: 161 QQVQVEAGALLQHALLLGDDEPESGRGAAEAQAG 194
+ E + G++E G+G E + G
Sbjct: 832 EGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEG 865
Score = 39.7 bits (91), Expect = 0.002
Identities = 36/156 (23%), Positives = 64/156 (41%), Gaps = 12/156 (7%)
Query: 31 GQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQGGSC 90
G+EG+ G + E GE +G E+ GE E + +EGEG+
Sbjct: 925 GEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGE---- 980
Query: 91 GHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQPGQAKE 150
G + +G+ E+ +G E EG + G G+ + E G + G G+ +E
Sbjct: 981 GEEEEGEGEGEEEEGEE----EGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEE 1036
Query: 151 GTDAAHGHDEQQVQVEAGALLQHALLLGDDEPESGR 186
G +E + + + G ++ ++E E G+
Sbjct: 1037 ----EEGEEEGEEREKEGEGEENRRNREEEEEEEGK 1068
Score = 39.7 bits (91), Expect = 0.002
Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 4/107 (3%)
Query: 28 GGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGE-HHHAERHCEDEDEGEGQ 86
G G +EG+ G +EE GE +G GE+ GE E E+E+EGE +
Sbjct: 964 GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE-EEGEEEGEGEEEGEGEGEEEEEGEVE 1022
Query: 87 GGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVG 133
G G +G +G+ E+ +G E+ + G + + + E G
Sbjct: 1023 GEVEGEEG--EGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEG 1067
Score = 33.5 bits (75), Expect = 0.17
Identities = 36/169 (21%), Positives = 62/169 (36%), Gaps = 16/169 (9%)
Query: 38 GLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQGGSCGH----- 92
G ++S G E+ E G S G + + E+ +D+ GE + G
Sbjct: 639 GKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAE 698
Query: 93 -------DGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQP 145
DG EQ Q E+ QG ++ + + GG + H + E + G +
Sbjct: 699 KEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEE-HGEGEEEEGDREEEEEKEGEGKE 757
Query: 146 GQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEPESGRGAAEAQAG 194
E + +E + + E A + G++E + G G E G
Sbjct: 758 EGEGEEVEGEREKEEGERKKEERAGKEEK---GEEEGDQGEGEEEETEG 803
Score = 30.4 bits (67), Expect = 1.4
Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 17/87 (19%)
Query: 28 GGGGQEGKWGGLSRSTGRQE-----EPGEADGRAYTFHLSVGEDTGEHHHAE-------R 75
G G +EG+ G G E E GE +G GE+ GE E R
Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEE-----EEGEEEGEEREKEGEGEENRR 1057
Query: 76 HCEDEDEGEGQGGSCGHDGPEQGQAEQ 102
+ E+E+E EG+ G + E+ E+
Sbjct: 1058 NREEEEEEEGKYQETGEEENERQDGEE 1084
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 46.2 bits (108), Expect = 3e-05
Identities = 61/245 (24%), Positives = 86/245 (35%), Gaps = 53/245 (21%)
Query: 9 TPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEP--GEADGRA---------Y 57
T +R+ L G G EG+ G S+ R ++P GEA+G A +
Sbjct: 1718 TSTRTVQGAEGGLGPGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTH 1777
Query: 58 TFHLSVGEDTGEHHHAERHCEDEDEGEGQGGSCGH-------------------DGPEQG 98
S G + GE + E GQG GH DG E
Sbjct: 1778 NSETSAGSELGEAEQEGEGISERGETGGQGS--GHEDNLQGEAAAGGDQDPGQSDGAEGI 1835
Query: 99 QAEQLQGREQVHTEG---PDLGGGDRCHSLAHDSERVGVSDRADSGSSQPGQ-------- 147
+A + +G Q +EG P+ G + E V G +QP
Sbjct: 1836 EAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEA 1895
Query: 148 ------AKEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEPES-GRGAAEAQAGLSSADH 200
EG +A E Q + E+ L+ G+DEPES G A EA+ A+
Sbjct: 1896 EWEVQPESEGAEAPEAEKEAQPETESVEALETE---GEDEPESEGAEAQEAEEAAQEAEG 1952
Query: 201 RVFPE 205
+ PE
Sbjct: 1953 QTQPE 1957
Score = 33.9 bits (76), Expect = 0.13
Identities = 42/140 (30%), Positives = 58/140 (41%), Gaps = 10/140 (7%)
Query: 33 EGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQGGSCGH 92
EG+ S QE GEA + + E GE AE E EGE Q S G
Sbjct: 2075 EGEAHPESEDVDAQEAEGEAQPESEG--VEAPEAEGEAQKAEGIEAPETEGEAQPESEGI 2132
Query: 93 DGPE-QGQAE-QLQGREQVHTEG---PDLGGGDRCHSLAH-DSERVGVSDRADSGSSQPG 146
+ PE +G+A+ + +G E EG P+ G + + E GV G +QP
Sbjct: 2133 EAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQP- 2191
Query: 147 QAKEGTDAAHGHDEQQVQVE 166
EG +A E Q ++E
Sbjct: 2192 -ESEGIEAPEAEGEAQPELE 2210
Score = 28.5 bits (62), Expect = 5.5
Identities = 46/196 (23%), Positives = 76/196 (38%), Gaps = 25/196 (12%)
Query: 29 GGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCE--------DE 80
G G E G + G ++PG++DG + E GE E E
Sbjct: 1807 GSGHEDNLQG-EAAAGGDQDPGQSDGAE---GIEAPEAEGEAQPESEGVEAPEAEGDAQE 1862
Query: 81 DEGEGQGGSCGHDGPE-----QGQAEQLQGRE-----QVHTEGPDLGGGDRCHSLAHDSE 130
EGE Q S + PE Q ++E ++ E Q +EG + ++ +S
Sbjct: 1863 AEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESV 1922
Query: 131 RVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEPES-GRGAA 189
++ D S+ +A+E +AA E Q Q E+ +++ + +PES A
Sbjct: 1923 EALETEGEDEPESEGAEAQEAEEAAQ-EAEGQTQPES-EVIESQEAEEEAQPESEDVEAL 1980
Query: 190 EAQAGLSSADHRVFPE 205
E + A+ PE
Sbjct: 1981 EVEVETQEAEGEAQPE 1996
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 45.8 bits (107), Expect = 3e-05
Identities = 50/219 (22%), Positives = 75/219 (34%), Gaps = 29/219 (13%)
Query: 4 SLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSV 63
S + + +RS ++GS ++ G+ G S S + E DG ++
Sbjct: 530 SHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHS----- 584
Query: 64 GEDTGEHHHAERHCEDEDEGE-GQGGSCG-HDGPEQGQAEQLQGREQVHTEGPDLGGGDR 121
HH A + + GQG S G QG + Q H+E + G
Sbjct: 585 ---GSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSA 641
Query: 122 C---HSLAHDSERVGV-------SDRADSGSSQPGQAKEGT---------DAAHGHDEQQ 162
H A + R G DRA G S K GT AA H++ +
Sbjct: 642 SRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQAR 701
Query: 163 VQVEAGALLQHALLLGDDEPESGRGAAEAQAGLSSADHR 201
+H L D SG G +A + + + HR
Sbjct: 702 SSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHR 740
Score = 42.4 bits (98), Expect = 4e-04
Identities = 50/220 (22%), Positives = 79/220 (35%), Gaps = 16/220 (7%)
Query: 4 SLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSV 63
S+ SS S S ++ + S S V GQ G +SR T +++ G+ + + H
Sbjct: 1832 SVDSSGHSGSHHSHTTSQERSDV--SRGQSGS-RSVSRQTRNEKQSGDGSRHSGSRHHEA 1888
Query: 64 GEDTGEHHHAE---RHCEDEDEGEGQGGSCGHDGPEQGQAEQLQ------GREQVHTEGP 114
H++ QG S D QG +E + R + +
Sbjct: 1889 SSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWE 1948
Query: 115 DLGGGDRCHSLAHDSERVGVSDRADSGSSQPGQAKEGTD---AAHGHDEQQVQVEAGALL 171
G R H +H +R G ADS + E + AA H++ +
Sbjct: 1949 QSRDGSR-HPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGS 2007
Query: 172 QHALLLGDDEPESGRGAAEAQAGLSSADHRVFPECPASPS 211
H L D SG G +A + + + HR + AS S
Sbjct: 2008 HHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDS 2047
Score = 36.6 bits (83), Expect = 0.020
Identities = 32/118 (27%), Positives = 42/118 (35%), Gaps = 14/118 (11%)
Query: 30 GGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEG-EGQGG 88
G + G+ G E+P A GR T S G G HH R EGQ
Sbjct: 459 GERSGRSGSSLYQVSTHEQPDSAHGRTGT---STGGRQGSHHEQARDSSRHSASQEGQDT 515
Query: 89 SCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQPG 146
GH G +G + + V+ G HS +H S R+D+ Q G
Sbjct: 516 IRGHPGSSRGGRQGSHHEQSVNRSG---------HSGSHHSHTTS-QGRSDASHGQSG 563
Score = 35.8 bits (81), Expect = 0.034
Identities = 45/186 (24%), Positives = 65/186 (34%), Gaps = 11/186 (5%)
Query: 7 SSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGED 66
S+ SR S G ASS V G + S + G E+ +D ++ + H G
Sbjct: 2661 SADSSRHSGIGHGQ-ASSAVRDSGHRGYSGSQASDNEGHSED---SDTQSVSAHGQAGSH 2716
Query: 67 TGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLA 126
H + R E G GS + Q+E G T G G R H A
Sbjct: 2717 QQSHQESARGRSGETSGHS--GSFLYQVSTHEQSESSHGWTGPSTRGRQ---GSR-HEQA 2770
Query: 127 HDSERVGVS-DRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEPESG 185
DS R S D D+ PG ++ G H +G+ H G + G
Sbjct: 2771 QDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRG 2830
Query: 186 RGAAEA 191
+ + +
Sbjct: 2831 QSGSRS 2836
Score = 34.7 bits (78), Expect = 0.077
Identities = 32/146 (21%), Positives = 50/146 (34%), Gaps = 18/146 (12%)
Query: 40 SRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDE------GEGQGGSC--- 90
SR +G + + G+A + H GE H + + D G GQ S
Sbjct: 677 SRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRD 736
Query: 91 -GHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQPG--- 146
GH G QA +G + G G H S + DR+ S + G
Sbjct: 737 SGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHH--QQSHQESARDRSGERSRRSGSFL 794
Query: 147 ---QAKEGTDAAHGHDEQQVQVEAGA 169
+ ++++HG V G+
Sbjct: 795 YQVSTHKQSESSHGWTGPSTGVRQGS 820
Score = 33.5 bits (75), Expect = 0.17
Identities = 39/163 (23%), Positives = 53/163 (32%), Gaps = 16/163 (9%)
Query: 31 GQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEG-EGQGGS 89
G+ G+ G E+ A GRA S G G H R EGQ
Sbjct: 3702 GRSGRSGSFLYQVSTHEQSESAHGRAGP---STGGRQGSRHEQARDSSRHSASQEGQDTI 3758
Query: 90 CGHDGPEQGQAEQLQGRE-QVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQPGQA 148
GH G +G GR+ H + D G HS +H S R+D+ Q G
Sbjct: 3759 RGHPGSRRG------GRQGSYHEQSVDRSG----HSGSHHSHTTS-QGRSDASHGQSGSR 3807
Query: 149 KEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEPESGRGAAEA 191
+ + +G+ A D S G E+
Sbjct: 3808 SASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGES 3850
Score = 32.7 bits (73), Expect = 0.29
Identities = 38/135 (28%), Positives = 50/135 (37%), Gaps = 21/135 (15%)
Query: 40 SRSTGRQEEPGEADGRAYTFH----LSVGEDTGEHHH----AERHCEDEDEGEGQGGSC- 90
SR +G + G+A + H S GE G HH + RH G GQ S
Sbjct: 2299 SRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRH---SGIGHGQASSAV 2355
Query: 91 ---GHDGPEQGQAEQLQGR-EQVHTEGPDLGGGDRCHSLAHD----SERVGVSDRADSGS 142
GH G QA +G E T+ G H +H G S R+ S
Sbjct: 2356 RDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFL 2415
Query: 143 SQPGQAKEGTDAAHG 157
Q E +++AHG
Sbjct: 2416 YQV-STHEQSESAHG 2429
Score = 32.7 bits (73), Expect = 0.29
Identities = 39/153 (25%), Positives = 54/153 (35%), Gaps = 25/153 (16%)
Query: 7 SSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGED 66
S+ SR S G ASS V G + S S G E+ +D ++ + H G
Sbjct: 2337 SADSSRHSGIGHGQ-ASSAVRDSGHRGSSGSQASDSEGHSED---SDTQSVSAHGQAGPH 2392
Query: 67 TGEHHHAERHCEDEDEGE-GQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSL 125
H + R G G+ GS + Q+E GR T G
Sbjct: 2393 QQSHQESTR---GRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGG------------ 2437
Query: 126 AHDSERVGVSDRADSGSSQPGQAKEGTDAAHGH 158
R G + SS+ ++EG D HGH
Sbjct: 2438 -----RQGSHHKQARDSSRHSTSQEGQDTIHGH 2465
Score = 32.7 bits (73), Expect = 0.29
Identities = 38/135 (28%), Positives = 50/135 (37%), Gaps = 21/135 (15%)
Query: 40 SRSTGRQEEPGEADGRAYTFH----LSVGEDTGEHHH----AERHCEDEDEGEGQGGSC- 90
SR +G + G+A + H S GE G HH + RH G GQ S
Sbjct: 3595 SRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRH---SGIGHGQASSAV 3651
Query: 91 ---GHDGPEQGQAEQLQGR-EQVHTEGPDLGGGDRCHSLAHD----SERVGVSDRADSGS 142
GH G QA +G E T+ G H +H G S R+ S
Sbjct: 3652 RDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFL 3711
Query: 143 SQPGQAKEGTDAAHG 157
Q E +++AHG
Sbjct: 3712 YQV-STHEQSESAHG 3725
Score = 32.0 bits (71), Expect = 0.50
Identities = 32/145 (22%), Positives = 47/145 (32%), Gaps = 29/145 (20%)
Query: 40 SRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDE------GEGQGGSC--- 90
SR +G + + G+ + H GE H H + D G GQ S
Sbjct: 353 SRQSGTRHAETSSRGQTASSHEQARSSPGERH-GSGHQQSADSSRHSATGRGQASSAVSD 411
Query: 91 -GHDGPEQGQAEQLQG------------------REQVHTEGPDLGGGDRCHSLAHDSER 131
GH G QA +G R+Q H E G+R +
Sbjct: 412 RGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQ 471
Query: 132 VGVSDRADSGSSQPGQAKEGTDAAH 156
V ++ DS + G + G +H
Sbjct: 472 VSTHEQPDSAHGRTGTSTGGRQGSH 496
Score = 32.0 bits (71), Expect = 0.50
Identities = 35/134 (26%), Positives = 48/134 (35%), Gaps = 19/134 (14%)
Query: 40 SRSTGRQEEPGEADGRAYTFH----LSVGEDTGEHHH----AERHCEDEDEGEGQGGSC- 90
SR +G + + G+A + H S GE G HH + RH G GQ S
Sbjct: 2623 SRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRH---SGIGHGQASSAV 2679
Query: 91 ---GHDGPEQGQAEQLQGR-EQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQ-- 144
GH G QA +G E T+ G H +H G S S
Sbjct: 2680 RDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFL 2739
Query: 145 -PGQAKEGTDAAHG 157
E ++++HG
Sbjct: 2740 YQVSTHEQSESSHG 2753
Score = 32.0 bits (71), Expect = 0.50
Identities = 35/134 (26%), Positives = 48/134 (35%), Gaps = 19/134 (14%)
Query: 40 SRSTGRQEEPGEADGRAYTFH----LSVGEDTGEHHH----AERHCEDEDEGEGQGGSC- 90
SR +G + + G+A + H S GE G HH + RH G GQ S
Sbjct: 2947 SRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRH---SGIGHGQASSAV 3003
Query: 91 ---GHDGPEQGQAEQLQGR-EQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQ-- 144
GH G QA +G E T+ G H +H G S S
Sbjct: 3004 RDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFL 3063
Query: 145 -PGQAKEGTDAAHG 157
E ++++HG
Sbjct: 3064 YQVSTHEQSESSHG 3077
Score = 30.4 bits (67), Expect = 1.4
Identities = 28/124 (22%), Positives = 39/124 (31%), Gaps = 3/124 (2%)
Query: 50 GEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQV 109
G G Y + +G HH E D GQ GS Q + E+ G
Sbjct: 1822 GGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGS--RSVSRQTRNEKQSGDGSR 1879
Query: 110 HTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGA 169
H+ R S H G S + +Q + +D + GH E + A
Sbjct: 1880 HSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSD-SQGHSEDSERWSGSA 1938
Query: 170 LLQH 173
H
Sbjct: 1939 SRNH 1942
Score = 30.0 bits (66), Expect = 1.9
Identities = 33/115 (28%), Positives = 39/115 (33%), Gaps = 11/115 (9%)
Query: 30 GGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQGGS 89
G + G+ G E+ A GR T + G H A EGQ
Sbjct: 1756 GERSGRSGSFLYQVSTHEQSESAHGR--TGPSTGGRQRSRHEQARDSSRHSASQEGQDTI 1813
Query: 90 CGHDGPEQGQAEQLQGREQVHTEG--PDLGGGDRCHSLAHDSERVGVSDRADSGS 142
GH G +G GR+ H E G HS ER VS R SGS
Sbjct: 1814 RGHPGSSRG------GRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVS-RGQSGS 1861
Score = 29.6 bits (65), Expect = 2.5
Identities = 33/133 (24%), Positives = 47/133 (35%), Gaps = 17/133 (12%)
Query: 40 SRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDE------GEGQGGSC--- 90
SR +G + G+A + H GE H RH + D G Q S
Sbjct: 1326 SRQSGTHHTESSSHGQAVSSHEQARSSPGE-RHGSRHQQSADSSRHSGIGHRQASSAVRD 1384
Query: 91 -GHDGPEQGQAEQLQGR-EQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQ---- 144
GH G Q +G E T+ G H +H G S + SG S+
Sbjct: 1385 SGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGES-SGRSRSFLY 1443
Query: 145 PGQAKEGTDAAHG 157
+ E +++ HG
Sbjct: 1444 QVSSHEQSESTHG 1456
Score = 29.6 bits (65), Expect = 2.5
Identities = 42/173 (24%), Positives = 58/173 (33%), Gaps = 33/173 (19%)
Query: 30 GGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHH-HAERHCEDEDEGEGQGG 88
G G+ G E+ G++ S G G H+ A+ EGQ
Sbjct: 2081 GESSGRSGSFLYQVSTHEQSESTHGQSAP---STGGRQGSHYDQAQDSSRHSASQEGQDT 2137
Query: 89 SCGHDGPEQGQAEQLQGREQVHTE-GPDLGGGDRCHSLAHDSERVGVSDRADSGSSQPGQ 147
GH GP +G GR+ H E D G HS +H S R+D+ Q G
Sbjct: 2138 IRGHPGPSRG------GRQGSHQEQSVDRSG----HSGSHHSHTTS-QGRSDASRGQSGS 2186
Query: 148 AKEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEPESGRGAAEAQAGLSSADH 200
+D++Q GD SG EA + S+ H
Sbjct: 2187 RSASRKT---YDKEQ--------------SGDGSRHSGSHHHEASSWADSSRH 2222
Score = 29.6 bits (65), Expect = 2.5
Identities = 34/151 (22%), Positives = 54/151 (35%), Gaps = 23/151 (15%)
Query: 13 SSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHH 72
S ++GS ++ G+ G S S + E DG ++ HH
Sbjct: 2809 SGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHS--------GSRHHE 2860
Query: 73 AERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSER- 131
A H + H QGQ+E G + +G + + DSER
Sbjct: 2861 ASTHADISR----------HSQAVQGQSE---GSRRSRRQGSSVSQDSDSEGHSEDSERW 2907
Query: 132 VGVSDRADSGSSQPGQAKEGTDAAHGHDEQQ 162
G + R GS+Q Q ++G+ H E +
Sbjct: 2908 SGSASRNHHGSAQE-QLRDGSRHPRSHQEDR 2937
Score = 28.9 bits (63), Expect = 4.2
Identities = 40/169 (23%), Positives = 61/169 (36%), Gaps = 35/169 (20%)
Query: 31 GQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQGGSC 90
GQ G SR+T +E+ G++ + + HH A H +
Sbjct: 3154 GQSGSRSA-SRTTRNEEQSGDSSRHSVS----------RHHEASTHADISR--------- 3193
Query: 91 GHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSER-VGVSDRADSGSSQPGQAK 149
H QGQ+E G + +G + + DSER G + R GS Q Q++
Sbjct: 3194 -HSQAVQGQSE---GSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQE-QSR 3248
Query: 150 EGTDAAHGHDEQQVQVEAGALLQHALLLGDDEPESGRGAAEAQAGLSSA 198
G+ H E + A D +SG AE +G +A
Sbjct: 3249 HGSRHPRSHHEDRAGHGHSA---------DRSRQSGTRHAETSSGGQAA 3288
Score = 28.5 bits (62), Expect = 5.5
Identities = 38/147 (25%), Positives = 52/147 (35%), Gaps = 12/147 (8%)
Query: 2 GISLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEAD--GRAYTF 59
G S S T S S++ + S S G+ G+ G S S Q E +T
Sbjct: 2697 GHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTG 2756
Query: 60 HLSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGG 119
+ G H A+ +GQ GH G +G GR+ H E G
Sbjct: 2757 PSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRG------GRQGYHHEHSVDSSG 2810
Query: 120 DRCHSLAHDSERVGVSDRADSGSSQPG 146
HS +H S R+D+ Q G
Sbjct: 2811 ---HSGSHHSHTTS-QGRSDASRGQSG 2833
Score = 27.7 bits (60), Expect = 9.4
Identities = 40/165 (24%), Positives = 61/165 (36%), Gaps = 32/165 (19%)
Query: 4 SLYSSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSV 63
S + + RS ++GS ++ G+ G SRS RQ + G
Sbjct: 1179 SHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSG--SRSASRQTRKDKQSG--------- 1227
Query: 64 GEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCH 123
G H RH E + S + GQ EQ G +G +
Sbjct: 1228 ---DGSRHSGSRHHEAASWADSSRHS------QVGQ-EQSSGSRTSRHQGSSVSQDSDSE 1277
Query: 124 SLAHDSERV-GVSDRADSGSSQPGQAKEGT---------DAAHGH 158
+ DSER+ G + R GSS+ Q+++G+ A+HGH
Sbjct: 1278 RHSDDSERLSGSASRNHHGSSRE-QSRDGSRHPGFHQEDRASHGH 1321
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 43.9 bits (102), Expect = 1e-04
Identities = 47/163 (28%), Positives = 68/163 (41%), Gaps = 14/163 (8%)
Query: 30 GGQEGKWGGLSRSTGRQE-EPGEADGRAYTFHLSVGEDTGEHHHAER------HCEDEDE 82
GGQE + STG E GE G T S GE E CEDE+E
Sbjct: 742 GGQEDV--AEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENE 799
Query: 83 GEGQGGSCGHD-GPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSG 141
EG+G + G D G + +++G E TE +L + H A + E+ GV D S
Sbjct: 800 AEGKGDNEGEDEGEIHAEDGEMKGNEG-ETESQELSAEN--HGEAKNDEK-GVEDGGGSD 855
Query: 142 SSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEPES 184
+ +E + +E++ Q E + G++EP S
Sbjct: 856 GGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLS 898
>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
Length = 517
Score = 42.7 bits (99), Expect = 3e-04
Identities = 49/168 (29%), Positives = 60/168 (35%), Gaps = 33/168 (19%)
Query: 28 GGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQG 87
GGGG G GG T + P A GED E E E+EDE G
Sbjct: 66 GGGGGGGGVGGGEAETMSEPSPESAS--------QAGEDEDEEEDDE---EEEDESSSSG 114
Query: 88 GSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQPGQ 147
G G E+ AE L G GG + E +S A S SS G
Sbjct: 115 G-----GEEESSAESLVGSS----------GG------SSSDETRSLSPGAASSSSGDGD 153
Query: 148 AKEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEP-ESGRGAAEAQAG 194
KEG + G Q G+ + G DE +G G + A +G
Sbjct: 154 GKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSG 201
>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
Length = 503
Score = 42.7 bits (99), Expect = 3e-04
Identities = 49/168 (29%), Positives = 60/168 (35%), Gaps = 33/168 (19%)
Query: 28 GGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQG 87
GGGG G GG T + P A GED E E E+EDE G
Sbjct: 66 GGGGGGGGVGGGEAETMSEPSPESAS--------QAGEDEDEEEDDE---EEEDESSSSG 114
Query: 88 GSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQPGQ 147
G G E+ AE L G GG + E +S A S SS G
Sbjct: 115 G-----GEEESSAESLVGSS----------GG------SSSDETRSLSPGAASSSSGDGD 153
Query: 148 AKEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEP-ESGRGAAEAQAG 194
KEG + G Q G+ + G DE +G G + A +G
Sbjct: 154 GKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSG 201
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 41.2 bits (95), Expect = 8e-04
Identities = 33/118 (27%), Positives = 46/118 (38%), Gaps = 10/118 (8%)
Query: 42 STGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAE 101
S +E+ E DG + +D + E ED EG G + G+DG E AE
Sbjct: 1948 SDDEEEDDDENDGEHEDYEEDEEDDDDDEDDTGMGDEGEDSNEGTGSADGNDGYEADDAE 2007
Query: 102 QLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSS---------QPGQAKE 150
G + +GGG+ H A DS+ G + + SS QP A E
Sbjct: 2008 GGDGTDPGTETEESMGGGEGNHRAA-DSQNSGEGNTGAAESSFSQEVSREQQPSSASE 2064
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 40.4 bits (93), Expect = 0.001
Identities = 47/158 (29%), Positives = 57/158 (36%), Gaps = 29/158 (18%)
Query: 28 GGGGQ---EGKWGGLSRSTGRQ--EEPGEADGRAYTFHL----SVGEDTGEHHH------ 72
GGGG EG GG+ S+G + E PG G + H S+G G H
Sbjct: 747 GGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGG 806
Query: 73 ---AERHCEDEDEGEGQGGSCGHDGPEQGQAEQL--QGREQVHTEGPDLGG--GDRCHSL 125
H E G G G GH P +G + G + H EGP GG G R H +
Sbjct: 807 ISGGSGHRPHEGPGGGMGAGGGH-RPHEGPGGSMGGSGGHRPH-EGPGHGGPHGHRPHDV 864
Query: 126 ----AHDSERVGVSD-RADSGSSQPGQAKEGTDAAHGH 158
HD + R G G G D H H
Sbjct: 865 PGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSH 902
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 40.4 bits (93), Expect = 0.001
Identities = 33/139 (23%), Positives = 51/139 (36%), Gaps = 29/139 (20%)
Query: 31 GQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTG-----EHHHAERHCEDEDEGEG 85
G + + G S +G +D R+ S ED +H +E +DEDEG
Sbjct: 63 GDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHR 122
Query: 86 QGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQP 145
G H E G ++ HS D E+ G D++D +
Sbjct: 123 SDGGSHHSEAE---------------------GSEKAHS---DDEKWGREDKSDQSDDEK 158
Query: 146 GQAKEGTDAAHGHDEQQVQ 164
Q + + A G DE ++Q
Sbjct: 159 IQNSDDEERAQGSDEDKLQ 177
Score = 32.3 bits (72), Expect = 0.38
Identities = 26/124 (20%), Positives = 47/124 (37%), Gaps = 2/124 (1%)
Query: 79 DEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRA 138
D+ E EG G D + + + E+ E D D+ ++ R+
Sbjct: 64 DDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRS 123
Query: 139 DSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEPESGRGAAEAQAGLSSA 198
D GS EG++ AH DE+ + + + D+ E +G+ E + S
Sbjct: 124 DGGSHH--SEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDD 181
Query: 199 DHRV 202
D ++
Sbjct: 182 DEKM 185
>gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b
[Homo sapiens]
Length = 806
Score = 39.7 bits (91), Expect = 0.002
Identities = 37/133 (27%), Positives = 52/133 (39%), Gaps = 16/133 (12%)
Query: 78 EDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDR 137
E+E+E E + G DG +Q++ E+ G G A + E G
Sbjct: 85 EEEEEEEEEEGISALDG------DQMELGEENGAAGAADSGPMEEEEAASEDEN-GDDQG 137
Query: 138 ADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEPESGRGAAEAQAGLSS 197
G + G +EG +GH EQQ Q A +P+ RGAA+ AG SS
Sbjct: 138 FQEGEDELGDEEEGAGDENGHGEQQPQPPA---------TQQQQPQQQRGAAKEAAGKSS 188
Query: 198 ADHRVFPECPASP 210
+F A P
Sbjct: 189 GPTSLFAVTVAPP 201
>gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a
[Homo sapiens]
Length = 825
Score = 39.7 bits (91), Expect = 0.002
Identities = 37/133 (27%), Positives = 52/133 (39%), Gaps = 16/133 (12%)
Query: 78 EDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDR 137
E+E+E E + G DG +Q++ E+ G G A + E G
Sbjct: 85 EEEEEEEEEEGISALDG------DQMELGEENGAAGAADSGPMEEEEAASEDEN-GDDQG 137
Query: 138 ADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEPESGRGAAEAQAGLSS 197
G + G +EG +GH EQQ Q A +P+ RGAA+ AG SS
Sbjct: 138 FQEGEDELGDEEEGAGDENGHGEQQPQPPA---------TQQQQPQQQRGAAKEAAGKSS 188
Query: 198 ADHRVFPECPASP 210
+F A P
Sbjct: 189 GPTSLFAVTVAPP 201
>gi|15721939 metastatic lymph node 51 [Homo sapiens]
Length = 703
Score = 39.7 bits (91), Expect = 0.002
Identities = 34/154 (22%), Positives = 53/154 (34%), Gaps = 13/154 (8%)
Query: 9 TPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTG 68
T S + S + GGG G GG G P + GR HL E G
Sbjct: 13 TEDEESGASGSDSGGSPLRGGGSCSGSAGG----GGSGSLPSQRGGRTGALHLRRVESGG 68
Query: 69 EHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHD 128
E CE ED EG ++ E + E+ + E+ ++ + +
Sbjct: 69 AKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENS---------KVELKSEA 119
Query: 129 SERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQ 162
++ V S + + G +P T D Q+
Sbjct: 120 NDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQE 153
>gi|190194423 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 39.3 bits (90), Expect = 0.003
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 12/149 (8%)
Query: 32 QEGKWGGLSRSTGRQEEPGEADGRAYTFHLSV-GEDTGEHHHAERHCEDEDEGEGQGGSC 90
QE +W TG + + T ++ E T + + R+ +D+G+ G
Sbjct: 289 QETEWQSQEGKTGLEAISNHKETEEKTVSEALLMEPTDDGNTTPRNHGVDDDGDDDGDDG 348
Query: 91 GHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAH----DSERVGVSDRADSGSSQPG 146
G DGP ++ Q E +R S+A+ + +R V + + G+++PG
Sbjct: 349 GTDGPRHSASDDYFIPSQAFLE------AERAQSIAYHLKIEEQREKVHENENIGTTEPG 402
Query: 147 QAKEGTDAAHGHDEQQVQVEAGALLQHAL 175
+ +E A + +E++ E G + HA+
Sbjct: 403 EHQEAKKAENSSNEEETSSE-GNMRVHAV 430
>gi|190341024 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 39.3 bits (90), Expect = 0.003
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 12/149 (8%)
Query: 32 QEGKWGGLSRSTGRQEEPGEADGRAYTFHLSV-GEDTGEHHHAERHCEDEDEGEGQGGSC 90
QE +W TG + + T ++ E T + + R+ +D+G+ G
Sbjct: 289 QETEWQSQEGKTGLEAISNHKETEEKTVSEALLMEPTDDGNTTPRNHGVDDDGDDDGDDG 348
Query: 91 GHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAH----DSERVGVSDRADSGSSQPG 146
G DGP ++ Q E +R S+A+ + +R V + + G+++PG
Sbjct: 349 GTDGPRHSASDDYFIPSQAFLE------AERAQSIAYHLKIEEQREKVHENENIGTTEPG 402
Query: 147 QAKEGTDAAHGHDEQQVQVEAGALLQHAL 175
+ +E A + +E++ E G + HA+
Sbjct: 403 EHQEAKKAENSSNEEETSSE-GNMRVHAV 430
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 37.7 bits (86), Expect = 0.009
Identities = 44/200 (22%), Positives = 64/200 (32%), Gaps = 27/200 (13%)
Query: 7 SSTPSRSSN-TGSASLASSCVWGGG-GQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVG 64
S +PSR + +GS +S +G G G G +G G + R+ G
Sbjct: 2416 SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRS-------G 2468
Query: 65 EDTGEHHHAERHCEDEDEGE-----GQGGSCGHDGPEQGQAEQ--LQGREQVHTEGPDLG 117
+ +G H G+ GQ SCG G GQ+ G + G
Sbjct: 2469 QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 2528
Query: 118 GGDRCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLL 177
G S H G G G + + HG L +
Sbjct: 2529 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG-----------LGESSGF 2577
Query: 178 GDDEPESGRGAAEAQAGLSS 197
G E SG+ ++ +Q G S
Sbjct: 2578 GHHESSSGQSSSYSQHGSGS 2597
Score = 37.0 bits (84), Expect = 0.015
Identities = 46/199 (23%), Positives = 64/199 (32%), Gaps = 25/199 (12%)
Query: 7 SSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEE-PGEADGRAYTFHLSVGE 65
S +PSR + + +SS G G G S S G E G + G + S G+
Sbjct: 1946 SPSPSRGRHGSGSGQSSSY-----GPYGSGSGWSSSRGPYESGSGHSSGLGHRESRS-GQ 1999
Query: 66 DTGEHHHAERHCEDEDEGE-----GQGGSCGHDGPEQGQAEQ--LQGREQVHTEGPDLGG 118
+G H G+ GQ SCG G GQ+ G + G G
Sbjct: 2000 SSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQG 2059
Query: 119 GDRCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLG 178
S H G G G + + HG L + G
Sbjct: 2060 SGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPG-----------LGESSGFG 2108
Query: 179 DDEPESGRGAAEAQAGLSS 197
E SG+ ++ +Q G S
Sbjct: 2109 HHESSSGQSSSYSQHGSGS 2127
Score = 36.2 bits (82), Expect = 0.026
Identities = 40/164 (24%), Positives = 54/164 (32%), Gaps = 9/164 (5%)
Query: 7 SSTPSRSSNTGSAS-LASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGE 65
S SRS GS+S L+SS G G G + +G P + + H S
Sbjct: 733 SGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHG 792
Query: 66 DTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGG---GDRC 122
G C + G GQ G GQ G H G G
Sbjct: 793 QHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSS 852
Query: 123 HSLAHD-----SERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQ 161
S HD S G + A +S G+ G+ + GH ++
Sbjct: 853 SSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQR 896
Score = 35.8 bits (81), Expect = 0.034
Identities = 46/202 (22%), Positives = 68/202 (33%), Gaps = 31/202 (15%)
Query: 7 SSTPSRSSN-TGSASLASSCVWGGGG----QEGKW-GGLSRSTG---RQEEPGEADGRAY 57
S +PSR + +GS +S +G G G + G S S+G R+ G++ G
Sbjct: 1476 SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSG--- 1532
Query: 58 TFHLSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQ--LQGREQVHTEGPD 115
G+ H+ H + GQ SCG G GQ+ G + G
Sbjct: 1533 -----YGQHGSSSGHSSTHGQ-HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG 1586
Query: 116 LGGGDRCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHAL 175
G S H G G G + + HG L +
Sbjct: 1587 RQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG-----------LGESS 1635
Query: 176 LLGDDEPESGRGAAEAQAGLSS 197
G E SG+ ++ +Q G S
Sbjct: 1636 GFGHHESSSGQSSSYSQHGSGS 1657
Score = 35.4 bits (80), Expect = 0.045
Identities = 42/200 (21%), Positives = 61/200 (30%), Gaps = 27/200 (13%)
Query: 7 SSTPSRSSNTGSASLASSC--VWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVG 64
S +PSR + + +SS G G G +G G + R+ G
Sbjct: 1006 SPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRS-------G 1058
Query: 65 EDTGEHHHAERHCEDEDEGE-----GQGGSCGHDGPEQGQAEQ--LQGREQVHTEGPDLG 117
+ +G H G+ GQ SCG G GQ+ G + G
Sbjct: 1059 QSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 1118
Query: 118 GGDRCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLL 177
G S H G G G + + HG L +
Sbjct: 1119 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSG-----------LGESSGF 1167
Query: 178 GDDEPESGRGAAEAQAGLSS 197
G E SG+ ++ +Q G S
Sbjct: 1168 GHHESSSGQSSSYSQHGSGS 1187
Score = 32.7 bits (73), Expect = 0.29
Identities = 41/157 (26%), Positives = 56/157 (35%), Gaps = 32/157 (20%)
Query: 7 SSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEE-PGEADGRAYTFHLSVGE 65
S +PSR + + +SS G G G S S G E G + G + S G+
Sbjct: 540 SPSPSRGRHESGSRQSSSY-----GPHGYGSGRSSSRGPYESGSGHSSGLGHQESRS-GQ 593
Query: 66 DTGEHHHAERHCEDEDEGE-----GQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGD 120
+G H G+ GQ SCG G GQ+ H G
Sbjct: 594 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSS----HGQHGSG------- 642
Query: 121 RCHSLAHDSERVGVSDRADSGSSQ-PGQAKEGTDAAH 156
+ S R G + SGS Q P + + G+D H
Sbjct: 643 -----SSQSSRYG---QQGSGSGQSPSRGRHGSDFGH 671
Score = 32.7 bits (73), Expect = 0.29
Identities = 41/198 (20%), Positives = 67/198 (33%), Gaps = 22/198 (11%)
Query: 7 SSTPSRSSNTGSASLASSCVWGGGGQEG--KWGGLSRSTGRQEEPGEADGRAYTFHLSVG 64
SS S++G +S + G G + G S + R E+ G + G + ++
Sbjct: 929 SSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSY----- 983
Query: 65 EDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHS 124
G+H R + G GQ GS P + G Q + GP G S
Sbjct: 984 ---GQHGSGSR----QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSS 1036
Query: 125 L----AHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDD 180
+ G+ R G + G+ + H Q G+ + G
Sbjct: 1037 RGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQ----HGSTSGQSSSCGQH 1092
Query: 181 EPESGRGAAEAQAGLSSA 198
SG+ ++ Q G S+
Sbjct: 1093 GASSGQSSSHGQHGSGSS 1110
Score = 32.7 bits (73), Expect = 0.29
Identities = 41/167 (24%), Positives = 52/167 (31%), Gaps = 29/167 (17%)
Query: 7 SSTPSRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGR----------QEEPGEADGRA 56
S + SR GS S SS G G++G G S S GR + G GR+
Sbjct: 1683 SRSSSRYGQHGSGSRQSS----GHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRS 1738
Query: 57 -----YTFHLSVGEDTGEHHHAERHCED-EDEGEGQGGSCGHDGPEQGQAEQLQGREQVH 110
Y G+H H G G G C QGQ G+
Sbjct: 1739 SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFC-----SQGQHGSTSGQSSTF 1793
Query: 111 TEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHG 157
D G S +H G S + G G + + HG
Sbjct: 1794 ----DQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHG 1836
Score = 32.0 bits (71), Expect = 0.50
Identities = 39/179 (21%), Positives = 58/179 (32%), Gaps = 31/179 (17%)
Query: 28 GGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQG 87
G G+ G S + R E G + G + ++ G+H R + G +
Sbjct: 486 GHSSGHGQHGSRSGQSSRGERQGSSAGSSSSY--------GQHGSGSR----QSLGHSRH 533
Query: 88 GSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHS-------------LAHDSERVGV 134
GS P + G Q + GP G R S L H R G
Sbjct: 534 GSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQ 593
Query: 135 SDRADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEPESGRGAAEAQA 193
S SG Q G + G + HG ++ + QH G G+ +Q+
Sbjct: 594 S----SGYGQHG-SSSGHSSTHG-QHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQS 646
Score = 30.8 bits (68), Expect = 1.1
Identities = 35/167 (20%), Positives = 56/167 (33%), Gaps = 22/167 (13%)
Query: 37 GGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPE 96
G S + R E+ G + G + ++ G+H R + G GQ GS P
Sbjct: 1901 GSRSGQSSRGEQHGSSSGSSSSY--------GQHGSGSR----QSLGHGQHGSGSGQSPS 1948
Query: 97 QGQAEQLQGREQVHTEGPDLGGGDRCHSL-----AHDSERVGVSDRADSGSSQPGQAKEG 151
+ G Q + GP G G S + G+ R G + G
Sbjct: 1949 PSRGRHGSGSGQSSSYGP-YGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHG 2007
Query: 152 TDAAHGHDEQQVQVEAGALLQHALLLGDDEPESGRGAAEAQAGLSSA 198
+ + H Q G+ + G SG+ ++ Q G S+
Sbjct: 2008 SSSGHSSTHGQ----HGSASGQSSSCGQHGASSGQSSSHGQHGSGSS 2050
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 35.8 bits (81), Expect = 0.034
Identities = 33/136 (24%), Positives = 44/136 (32%), Gaps = 15/136 (11%)
Query: 45 RQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQGGSCGH-------DGPEQ 97
+ E +DG G DTG ERH E+E G GH D P
Sbjct: 20 QDERDSGSDGEDDVNEQHSGSDTGS---VERHSENETSDREDGLPKGHHVTDSENDEPLN 76
Query: 98 GQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQ-----PGQAKEGT 152
A + E + D +R A DSE V+ S+ PG E
Sbjct: 77 LNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENE 136
Query: 153 DAAHGHDEQQVQVEAG 168
+ +GH + G
Sbjct: 137 ELLNGHASDSENEDVG 152
Score = 28.1 bits (61), Expect = 7.2
Identities = 35/153 (22%), Positives = 58/153 (37%), Gaps = 29/153 (18%)
Query: 59 FHLSVGEDTGEHHHAERHCEDEDEGEGQGGSCG-------HDGPEQGQAEQLQGREQVHT 111
FH S E+ E H ++ DEDE EG+ D ++ +A + R
Sbjct: 360 FHSSDSEE--EEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDA 417
Query: 112 EGPDLG-----GGDRCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQVE 166
+ D G R ++A DSE + +D + + + G+D+ G++E+
Sbjct: 418 DDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEE--KDLFGSDSESGNEEEN---- 471
Query: 167 AGALLQHALLLGDDEPESGRGAAEAQAGLSSAD 199
L+ D ESG E G + D
Sbjct: 472 ---------LIADIFGESGDEEEEEFTGFNQED 495
>gi|239756943 PREDICTED: hypothetical protein [Homo sapiens]
Length = 783
Score = 35.4 bits (80), Expect = 0.045
Identities = 40/162 (24%), Positives = 59/162 (36%), Gaps = 21/162 (12%)
Query: 80 EDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRAD 139
E+ G GG G + +AE+ QG ++ GP + +GV + +
Sbjct: 360 EEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGP------------QQAPFLGVLHKGE 407
Query: 140 SGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQ------HALLLGDDEPESGRGAAEAQA 193
+G G+ K G +A H Q A+ Q AL + G G E +
Sbjct: 408 AGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEE 467
Query: 194 GLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTW 235
S A H+ F + LW LA+ S PLQ W
Sbjct: 468 RQSQAHHQGFVDGHPGSQARLW-LALTWDSP--PAPLQRSVW 506
>gi|239751443 PREDICTED: hypothetical protein [Homo sapiens]
Length = 783
Score = 35.4 bits (80), Expect = 0.045
Identities = 40/162 (24%), Positives = 59/162 (36%), Gaps = 21/162 (12%)
Query: 80 EDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRAD 139
E+ G GG G + +AE+ QG ++ GP + +GV + +
Sbjct: 360 EEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGP------------QQAPFLGVLHKGE 407
Query: 140 SGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQ------HALLLGDDEPESGRGAAEAQA 193
+G G+ K G +A H Q A+ Q AL + G G E +
Sbjct: 408 AGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEE 467
Query: 194 GLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTW 235
S A H+ F + LW LA+ S PLQ W
Sbjct: 468 RQSQAHHQGFVDGHPGSQARLW-LALTWDSP--PAPLQRSVW 506
>gi|239745948 PREDICTED: hypothetical protein XP_002343622 [Homo
sapiens]
Length = 791
Score = 35.4 bits (80), Expect = 0.045
Identities = 40/162 (24%), Positives = 59/162 (36%), Gaps = 21/162 (12%)
Query: 80 EDEGEGQGGSCGHDGPEQGQAEQLQGREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRAD 139
E+ G GG G + +AE+ QG ++ GP + +GV + +
Sbjct: 368 EEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGP------------QQAPFLGVLHKGE 415
Query: 140 SGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQ------HALLLGDDEPESGRGAAEAQA 193
+G G+ K G +A H Q A+ Q AL + G G E +
Sbjct: 416 AGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEE 475
Query: 194 GLSSADHRVFPECPASPSIWLWNLAVPVHSVRIQIPLQSKTW 235
S A H+ F + LW LA+ S PLQ W
Sbjct: 476 RQSQAHHQGFVDGHPGSQARLW-LALTWDSP--PAPLQRSVW 514
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 35.0 bits (79), Expect = 0.059
Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 10/96 (10%)
Query: 63 VGEDTGEHHHAERHCEDEDEGEG-------QGGSCGHDGPEQGQAEQLQGREQVHTEGPD 115
V E+ GE E E+E+E EG +GGS E+ + EQ +G + EG +
Sbjct: 520 VKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEE 579
Query: 116 LGGGDRCHSLAHDSERVGVSDR--ADSGSSQPGQAK 149
+ + SE V + AD+ +P +AK
Sbjct: 580 AEAKEE-KKVEEKSEEVATKEELVADAKVEKPEKAK 614
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 35.0 bits (79), Expect = 0.059
Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 10/96 (10%)
Query: 63 VGEDTGEHHHAERHCEDEDEGEG-------QGGSCGHDGPEQGQAEQLQGREQVHTEGPD 115
V E+ GE E E+E+E EG +GGS E+ + EQ +G + EG +
Sbjct: 144 VKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEE 203
Query: 116 LGGGDRCHSLAHDSERVGVSDR--ADSGSSQPGQAK 149
+ + SE V + AD+ +P +AK
Sbjct: 204 AEAKEE-KKVEEKSEEVATKEELVADAKVEKPEKAK 238
>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
Length = 686
Score = 35.0 bits (79), Expect = 0.059
Identities = 48/198 (24%), Positives = 76/198 (38%), Gaps = 38/198 (19%)
Query: 33 EGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQGG-SCG 91
EG+ G + G + +A+GR + G+ G+ A D E EG G S
Sbjct: 223 EGRVGDSVDAEGPAGDSVDAEGRVGD-SVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMD 281
Query: 92 HDGPEQGQAEQLQGREQVHTEG----------------PDLGGGDRCHSLAHDSERVGVS 135
+GP G+A ++ G Q +G G+ A ++E GV
Sbjct: 282 AEGP-AGRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVK 340
Query: 136 D---------RADSGSSQPGQAKEGTDAAHGHDEQQVQVEAGALLQHALLLGDDEP---- 182
RAD+G + G +G G DE++ + + G++E
Sbjct: 341 GSEEAAPGDARADAGEDRVG---DGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSS 397
Query: 183 ---ESGRGAAEAQAGLSS 197
E+ RGAAE +A LS+
Sbjct: 398 PHGEASRGAAEPEAQLSN 415
Score = 31.2 bits (69), Expect = 0.85
Identities = 32/150 (21%), Positives = 50/150 (33%), Gaps = 19/150 (12%)
Query: 45 RQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQ 104
R EPG A G A E E+ G G GP++G + +
Sbjct: 27 RPGEPGAAGGEA------------EGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEAR 74
Query: 105 GREQVHTEGPDLGGGDRCHSLAHDSERVGVSDRADSGSSQPGQAKEGTDAAHGHDEQQVQ 164
G H E G + E + + + S PG+ +G G +++ +
Sbjct: 75 GTRGAHGETEAEEGAPEGAEVPQGGEETSGAQQVEGAS--PGRGAQG--EPRGEAQREPE 130
Query: 165 VEAGALLQHALLLGDDEPESGRGAAEAQAG 194
A Q + PE G+A +AG
Sbjct: 131 DSAAPERQEE---AEQRPEVPEGSASGEAG 157
>gi|221316599 chromogranin B precursor [Homo sapiens]
Length = 677
Score = 34.7 bits (78), Expect = 0.077
Identities = 36/148 (24%), Positives = 54/148 (36%), Gaps = 17/148 (11%)
Query: 35 KWG-GLSRSTGRQEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEG---QGGSC 90
KW G S R +EP Y V E+ H + EDE+E EG Q G
Sbjct: 122 KWAEGGGHSRERADEP---QWSLYPSDSQVSEEVKTRHSEKSQREDEEEEEGENYQKGER 178
Query: 91 GHDGPEQGQAEQ--------LQGREQVHT-EGPDLGGGDRCHSLAHDSERVGVSDRADSG 141
G D E+ E+ L R+Q + +L H+ H E+ +++
Sbjct: 179 GEDSSEEKHLEEPGETQNAFLNERKQASAIKKEELVARSETHAAGHSQEKTHSREKSSQE 238
Query: 142 S-SQPGQAKEGTDAAHGHDEQQVQVEAG 168
S + G + + G Q + E G
Sbjct: 239 SGEETGSQENHPQESKGQPRSQEESEEG 266
>gi|194272200 actin binding LIM protein family, member 2 isoform 3
[Homo sapiens]
Length = 572
Score = 34.7 bits (78), Expect = 0.077
Identities = 38/144 (26%), Positives = 50/144 (34%), Gaps = 37/144 (25%)
Query: 11 SRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDT--- 67
S S+TGS SL G++ SRS PG GR+ T LSV D+
Sbjct: 363 SSPSSTGSVSL------------GRYTPTSRSPQHYSRPGSESGRS-TPSLSVLSDSKPP 409
Query: 68 -GEHHHAERHCEDEDEG--------------------EGQGGSCGHDGPEQGQAEQLQGR 106
+ A RH D G +G+ GS D ++ L+G
Sbjct: 410 PSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSDGEDGSLDQDNRKKSSWLMLKGD 469
Query: 107 EQVHTEGPDLGGGDRCHSLAHDSE 130
T PDL HS D +
Sbjct: 470 ADTRTNSPDLDTQSLSHSSGTDRD 493
>gi|194272198 actin binding LIM protein family, member 2 isoform 2
[Homo sapiens]
Length = 611
Score = 34.7 bits (78), Expect = 0.077
Identities = 38/144 (26%), Positives = 50/144 (34%), Gaps = 37/144 (25%)
Query: 11 SRSSNTGSASLASSCVWGGGGQEGKWGGLSRSTGRQEEPGEADGRAYTFHLSVGEDT--- 67
S S+TGS SL G++ SRS PG GR+ T LSV D+
Sbjct: 363 SSPSSTGSVSL------------GRYTPTSRSPQHYSRPGSESGRS-TPSLSVLSDSKPP 409
Query: 68 -GEHHHAERHCEDEDEG--------------------EGQGGSCGHDGPEQGQAEQLQGR 106
+ A RH D G +G+ GS D ++ L+G
Sbjct: 410 PSTYQQAPRHFHVPDTGVKDNIYRKPPIYRQHAARRSDGEDGSLDQDNRKKSSWLMLKGD 469
Query: 107 EQVHTEGPDLGGGDRCHSLAHDSE 130
T PDL HS D +
Sbjct: 470 ADTRTNSPDLDTQSLSHSSGTDRD 493
>gi|54607124 RNA binding motif protein 15B [Homo sapiens]
Length = 890
Score = 33.9 bits (76), Expect = 0.13
Identities = 28/93 (30%), Positives = 35/93 (37%), Gaps = 6/93 (6%)
Query: 46 QEEPGEADGRAYTFHLSVGEDTGEHHHAERHCEDEDEGEGQGGSCGHDGPEQGQAEQLQG 105
+E EA GR H + G G H D+ G G GG DG G A
Sbjct: 26 REREAEAGGRRAA-HKASG---GAKHPVPARARDKPRGSGSGGGGHRDGRGTGDANHRAS 81
Query: 106 REQVHTEGPDLGGGDRCHSLAHDSERVGVSDRA 138
+ + G GGG R + D G+S RA
Sbjct: 82 SGR--SSGSGAGGGGRGGKASGDPGASGMSPRA 112
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,571,030
Number of Sequences: 37866
Number of extensions: 631219
Number of successful extensions: 2207
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 132
Number of HSP's that attempted gapping in prelim test: 1957
Number of HSP's gapped (non-prelim): 306
length of query: 242
length of database: 18,247,518
effective HSP length: 99
effective length of query: 143
effective length of database: 14,498,784
effective search space: 2073326112
effective search space used: 2073326112
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.