Guide to the Human Genome
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Search of human proteins with 239754458

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239754458 PREDICTED: hypothetical protein [Homo sapiens]
         (180 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239754458 PREDICTED: hypothetical protein [Homo sapiens]           385   e-108
gi|239749008 PREDICTED: hypothetical protein XP_002346879 [Homo ...   385   e-108
gi|239743028 PREDICTED: hypothetical protein XP_002342721 [Homo ...   385   e-108
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    59   2e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    59   2e-09
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     59   2e-09
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       59   2e-09
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       59   2e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    57   1e-08
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                57   1e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni...    56   1e-08
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    55   2e-08
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...    55   4e-08
gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]            54   7e-08
gi|148727370 immediate early response 5-like [Homo sapiens]            53   1e-07
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 52   2e-07
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 52   2e-07
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    52   3e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     52   3e-07
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]           52   3e-07
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    52   3e-07
gi|169171345 PREDICTED: hypothetical protein [Homo sapiens]            52   4e-07
gi|169172205 PREDICTED: hypothetical protein [Homo sapiens]            52   4e-07
gi|169170949 PREDICTED: hypothetical protein [Homo sapiens]            52   4e-07
gi|11386183 WAS protein family, member 2 [Homo sapiens]                52   4e-07
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         52   4e-07
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               52   4e-07
gi|150170670 piccolo isoform 2 [Homo sapiens]                          51   5e-07
gi|150378539 piccolo isoform 1 [Homo sapiens]                          51   5e-07
gi|18959210 WIRE protein [Homo sapiens]                                51   5e-07

>gi|239754458 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 180

 Score =  385 bits (990), Expect = e-108
 Identities = 180/180 (100%), Positives = 180/180 (100%)

Query: 1   MVPTCGENAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPV 60
           MVPTCGENAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPV
Sbjct: 1   MVPTCGENAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPV 60

Query: 61  SRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVS 120
           SRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVS
Sbjct: 61  SRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVS 120

Query: 121 RVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRGP 180
           RVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRGP
Sbjct: 121 RVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRGP 180


>gi|239749008 PREDICTED: hypothetical protein XP_002346879 [Homo
           sapiens]
          Length = 180

 Score =  385 bits (990), Expect = e-108
 Identities = 180/180 (100%), Positives = 180/180 (100%)

Query: 1   MVPTCGENAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPV 60
           MVPTCGENAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPV
Sbjct: 1   MVPTCGENAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPV 60

Query: 61  SRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVS 120
           SRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVS
Sbjct: 61  SRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVS 120

Query: 121 RVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRGP 180
           RVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRGP
Sbjct: 121 RVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRGP 180


>gi|239743028 PREDICTED: hypothetical protein XP_002342721 [Homo
           sapiens]
          Length = 180

 Score =  385 bits (990), Expect = e-108
 Identities = 180/180 (100%), Positives = 180/180 (100%)

Query: 1   MVPTCGENAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPV 60
           MVPTCGENAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPV
Sbjct: 1   MVPTCGENAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPV 60

Query: 61  SRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVS 120
           SRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVS
Sbjct: 61  SRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVS 120

Query: 121 RVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRGP 180
           RVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRGP
Sbjct: 121 RVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRGP 180


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 54/171 (31%), Positives = 68/171 (39%), Gaps = 17/171 (9%)

Query: 3   PTCGENAASCRSGSHFPPAARGRLPGETLSP-------SPRAAALPPLQQ--RPPGAPGA 53
           P    + A+   GS    A    LP   LSP       +P A ALPPLQ    PP +P  
Sbjct: 358 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 417

Query: 54  LGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRR 113
                P  + P A      Q P+ P P        +P A  P S S    + APP  +  
Sbjct: 418 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 477

Query: 114 PPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPP-RTARPRPAFTP 163
           P      +V PSP     +  S  P PQ   PPP+  PP + A+P P   P
Sbjct: 478 P-----LQVPPSPPASPPMSPSATPPPQ--APPPLAAPPLQLAKPPPQAPP 521



 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 53/174 (30%), Positives = 63/174 (36%), Gaps = 27/174 (15%)

Query: 19  PPAARGRLPGETLSP-SPRAAALPPLQ--QRPPGAPGALGRPK-------PVS---RGPR 65
           PPA+    P  T  P +P   A PPLQ  + PP AP AL  P        P S   + P 
Sbjct: 485 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 544

Query: 66  AGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPS 125
           +     P  P    P  AP    AP   VP S   P A+P   +  RRPPT         
Sbjct: 545 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPS---PPASPT-LQAPRRPPTPGPDTSVSG 600

Query: 126 PGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRG 179
           P     L          G PPP    P +    P         +  P  E+LRG
Sbjct: 601 PRLTLAL--------APGPPPPPSRSPSSTLSGPDLAGHSSSATSTP--EELRG 644



 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 42/121 (34%), Positives = 48/121 (39%), Gaps = 18/121 (14%)

Query: 20  PAARGRLPGETLSPSPRAAALPPLQQRPP-----GAPGALGRPKPVSRGPRAGLREWPQQ 74
           PAAR   PG  L+P P  +  PP    P      GA GA+GR     R    G    P+ 
Sbjct: 17  PAARA--PG-LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73

Query: 75  PWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVS-RVAPSPGRPAGLH 133
             R GP       R+        ASRP   PA  R  R PP    S     SPGR +G  
Sbjct: 74  APRAGP------TRSAGTSSRNPASRP---PASGRGERAPPAKNTSPGPVSSPGRASGTT 124

Query: 134 R 134
           R
Sbjct: 125 R 125



 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 53/183 (28%), Positives = 64/183 (34%), Gaps = 58/183 (31%)

Query: 20  PAARGRLPGE-----TLSPSPRAAALP-PLQQRPPGAPGALGRP-------------KPV 60
           P+AR R P E       S S  +   P P  +R P A G L RP              P 
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253

Query: 61  SRGPRA-GLREWPQQPWRPGPLGA----------PLQDRAPSAHVPGSASRPTATPAPPR 109
             GP A G    P  P +P P G           P +D AP+  +   +S P ATP+P  
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA--LGPLSSSPLATPSPSA 311

Query: 110 C--SRRPPT---------------TTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPP 152
              S+ PPT               T +    PSP  P  L            P P  TPP
Sbjct: 312 ALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQT---------LPSPPATPP 362

Query: 153 RTA 155
             A
Sbjct: 363 SQA 365



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 48/179 (26%), Positives = 65/179 (36%), Gaps = 26/179 (14%)

Query: 13  RSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSR-GP--RAGLR 69
           R+G         R P      S R    PP +   PG   + GR    +R GP  + GLR
Sbjct: 76  RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135

Query: 70  EWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRP 129
              ++    G      +  A SA     A R T+ P P       P+  ++R + + G  
Sbjct: 136 ISAEETVARGKATEAPKRSALSA----GARRDTSGPTP-----GTPSPAMARRSRAAGTE 186

Query: 130 AGLHRSREPRPQDGTPPPVDTPPR---------TARPRPAFTPRPVVGS--ERPRQEQL 177
            GL R   P P     PP + P +         T  P PA   RP  G   +RP    L
Sbjct: 187 VGLPR---PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 42/132 (31%), Positives = 51/132 (38%), Gaps = 23/132 (17%)

Query: 32  SPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAP-LQDRAP 90
           +P+ RA  L  L  RPPG+P    RP P            P  P     LGA     R P
Sbjct: 16  TPAARAPGL--LTPRPPGSP----RPPP------------PVTPAALRVLGAAGAVGRKP 57

Query: 91  SAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDT 150
            A   G     T   + PR        T SR  P+   PA     R P  ++ +P PV +
Sbjct: 58  LAERAGGIGGATIPESAPRAGPTRSAGTSSR-NPASRPPASGRGERAPPAKNTSPGPVSS 116

Query: 151 PPR---TARPRP 159
           P R   T RP P
Sbjct: 117 PGRASGTTRPGP 128


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 54/171 (31%), Positives = 68/171 (39%), Gaps = 17/171 (9%)

Query: 3   PTCGENAASCRSGSHFPPAARGRLPGETLSP-------SPRAAALPPLQQ--RPPGAPGA 53
           P    + A+   GS    A    LP   LSP       +P A ALPPLQ    PP +P  
Sbjct: 319 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378

Query: 54  LGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRR 113
                P  + P A      Q P+ P P        +P A  P S S    + APP  +  
Sbjct: 379 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 438

Query: 114 PPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPP-RTARPRPAFTP 163
           P      +V PSP     +  S  P PQ   PPP+  PP + A+P P   P
Sbjct: 439 P-----LQVPPSPPASPPMSPSATPPPQ--APPPLAAPPLQLAKPPPQAPP 482



 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 53/174 (30%), Positives = 63/174 (36%), Gaps = 27/174 (15%)

Query: 19  PPAARGRLPGETLSP-SPRAAALPPLQ--QRPPGAPGALGRPK-------PVS---RGPR 65
           PPA+    P  T  P +P   A PPLQ  + PP AP AL  P        P S   + P 
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 505

Query: 66  AGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPS 125
           +     P  P    P  AP    AP   VP S   P A+P   +  RRPPT         
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPS---PPASPT-LQAPRRPPTPGPDTSVSG 561

Query: 126 PGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRG 179
           P     L          G PPP    P +    P         +  P  E+LRG
Sbjct: 562 PRLTLAL--------APGPPPPPSRSPSSTLSGPDLAGHSSSATSTP--EELRG 605



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 54/194 (27%), Positives = 67/194 (34%), Gaps = 52/194 (26%)

Query: 20  PAARGRLPGE-----TLSPSPRAAALP-PLQQRPPGAPGALGRP-------------KPV 60
           P+AR R P E       S S  +   P P  +R P A G L RP              P 
Sbjct: 185 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 244

Query: 61  SRGPRA-GLREWPQQPWRPGPLGA----------PLQDRAPSAHVPGSASRPTATPAPPR 109
             GP A G    P  P +P P G           P +D AP+     S+   T +P+ P 
Sbjct: 245 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP 304

Query: 110 CSRRPPT---------TTVSRVAPSPGRPA-----------GLHRSREPRPQDGTPPPVD 149
               PP+         T  S+   S G P             L     P PQ   PP + 
Sbjct: 305 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ--APPALA 362

Query: 150 TPPRTARPRPAFTP 163
            PP  A P P  +P
Sbjct: 363 LPPLQAPPSPPASP 376



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 57/185 (30%), Positives = 69/185 (37%), Gaps = 33/185 (17%)

Query: 20  PAARGRLPGETLSPSPRAAALPPLQQRPP-----GAPGALGRPKPVSRGPRAGLREWPQQ 74
           PAAR   PG  L+P P  +  PP    P      GA GA+GR     R    G    P+ 
Sbjct: 17  PAARA--PG-LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73

Query: 75  PWRPGPL------GAPLQDRAPSAH--VPGSASRP-----TATPAP--PRCSRRPPTTTV 119
             R GP        +   +RAP A    PG  S P     T  P P   +  R     TV
Sbjct: 74  APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133

Query: 120 SR----VAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTAR------PRPAFTPRPVVGS 169
           +R     AP     +   R     P  GTP P       A       PRPA + RP   +
Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193

Query: 170 ERPRQ 174
           E PR+
Sbjct: 194 EGPRK 198



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 49/183 (26%), Positives = 68/183 (37%), Gaps = 14/183 (7%)

Query: 6   GENAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPG-ALGRPKPVSRGP 64
           GE A   ++ S  P ++ GR  G T  P P       +      A G A   PK  +   
Sbjct: 91  GERAPPAKNTSPGPVSSPGRASGTT-RPGPLGQKGLRISAEETVARGKATEAPKRSALSA 149

Query: 65  RAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSR--- 121
            A        P  P P  A  + RA    V      P+A P PP    R   ++ S    
Sbjct: 150 GARRDTSGPTPGTPSPAMAR-RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHST 208

Query: 122 VAPSPG---RPA---GLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQE 175
             PSP    RP+   GL R    R    +  P+ +P R+  P    TPR      +P+ +
Sbjct: 209 TEPSPAARRRPSAGGGLQRPAS-RSLSSSATPLSSPARSG-PSARGTPRAPAHPSQPKPK 266

Query: 176 QLR 178
            L+
Sbjct: 267 GLQ 269



 Score = 28.1 bits (61), Expect = 4.3
 Identities = 27/108 (25%), Positives = 36/108 (33%), Gaps = 28/108 (25%)

Query: 88  RAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRV-----------APSPGRPAGLHRSR 136
           R P+A  PG       TP PP   R PP  T + +            P   R  G+  + 
Sbjct: 15  RTPAARAPG-----LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69

Query: 137 EPR------PQDGTPPPVD------TPPRTARPRPAFTPRPVVGSERP 172
            P       P   + PP         P +   P P  +P    G+ RP
Sbjct: 70  IPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 117


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 50/167 (29%), Positives = 62/167 (37%), Gaps = 12/167 (7%)

Query: 7   ENAASCRSGSHFPPAARGRLP-----GETLSPSPRAAALPPLQQRPPGAPGALGRPKPVS 61
           + + S R+ +   P  RG  P         +P+  AAA PP    PP  P  +    P +
Sbjct: 88  KGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAP-A 146

Query: 62  RGPRAGLREWPQQPWRPGPL--GAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTV 119
           R PRA        P  PGP   G   Q  AP A  P + + P A   P    R PP    
Sbjct: 147 RAPRAAAAAATAPP-SPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVA 205

Query: 120 SRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPV 166
           +R  P P  P        P+ Q   PP    PP     R     RPV
Sbjct: 206 AREPPLPPPP---QPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPV 249


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 58.9 bits (141), Expect = 2e-09
 Identities = 74/232 (31%), Positives = 92/232 (39%), Gaps = 64/232 (27%)

Query: 2   VPTCGENAASCRSGSHFPPAARGRLP-GETLSPSPRAAALPPLQQRPP--GAPGALGRPK 58
           +P   +  AS   GSH    + G LP G   S  P   A PP QQRPP  G P   G P 
Sbjct: 418 LPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQP---AGPPAQQRPPPQGGPPQPG-PG 473

Query: 59  PVSRGPRAGLREWPQ-QPWRPG---PLGAPLQDRAPS----------------------- 91
           P  +GP    R  PQ Q    G   P G+PL  R PS                       
Sbjct: 474 PQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQS 533

Query: 92  ---AHVPGS--ASRPTATPAPPRCSRRPP----TTTVSRVAP---SPGRPAGLHRSREPR 139
              A  PG+  A+RP A+P+P R    PP     T+VS  AP   S   P G  R   P+
Sbjct: 534 RPVAGGPGAPPAARPPASPSPQR-QAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592

Query: 140 PQDG----------------TPPPVDTPPRTARPRPAFTPRPVVGSERPRQE 175
              G                T PP    PR + P PA  P+P + +++P Q+
Sbjct: 593 KPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQL-AQKPSQD 643



 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 50/159 (31%), Positives = 60/159 (37%), Gaps = 14/159 (8%)

Query: 32  SPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAG---LREWPQQPWRPGPLGAP-LQD 87
           +PSP A  L     + P  P A  RP P    P+ G    R+ P    RP P G   L  
Sbjct: 436 TPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSG 495

Query: 88  RAPSA--HVPGSASRPTATPAPPRCSRRPPTTTVSR----VAPSPGRPAGLHRSREPRPQ 141
             P A   +P     PT+ P  P     PPT    R    VA  PG P        P PQ
Sbjct: 496 LGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQ 555

Query: 142 DGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRGP 180
               PP  T  +T+   PA    P      P  +Q +GP
Sbjct: 556 RQAGPPQAT-RQTSVSGPA---PPKASGAPPGGQQRQGP 590



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 57/157 (36%), Positives = 65/157 (41%), Gaps = 31/157 (19%)

Query: 19  PPAARG---RLPGETLSPS-PRAAALPPLQ-----QRP----PGAPGALGRPKPVSRGPR 65
           PPA      RLP  T +P  P + A PP Q      RP    PGAP A   P   S   +
Sbjct: 498 PPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQ 557

Query: 66  AGLREWPQQPWRPGPL-----GAP---LQDRAPSAHVPGSASRPT--ATPAPPRCSRRPP 115
           AG  +  +Q    GP      GAP    Q + P    PG A  PT  A+ A P     PP
Sbjct: 558 AGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAG-PTRQASQAGPVPRTGPP 616

Query: 116 TTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPP 152
           TT   R  PS   PAG      P+PQ    P  D PP
Sbjct: 617 TTQQPR--PSGPGPAG-----RPKPQLAQKPSQDVPP 646



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 52/194 (26%), Positives = 63/194 (32%), Gaps = 43/194 (22%)

Query: 3   PTCGENAAS--CRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPV 60
           PT G+   S     G   PPAAR        SPSP+  A PP   R     G    P   
Sbjct: 525 PTQGQGRQSRPVAGGPGAPPAAR-----PPASPSPQRQAGPPQATRQTSVSGPA--PPKA 577

Query: 61  SRGPRAGLREW--PQQPWRPGPLG--------------APLQDRAPSAHVPGSASRPTAT 104
           S  P  G +    PQ+P  PGP G               P   + P    PG A RP   
Sbjct: 578 SGAPPGGQQRQGPPQKP--PGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQ 635

Query: 105 PAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPR 164
            A       PP  T +   P             P PQ      +        P P   PR
Sbjct: 636 LAQKPSQDVPPPATAAAGGP-------------PHPQLNKSQSLTNAFNLPEPAP---PR 679

Query: 165 PVVGSERPRQEQLR 178
           P +  +  + E +R
Sbjct: 680 PSLSQDEVKAETIR 693



 Score = 30.4 bits (67), Expect = 0.86
 Identities = 31/114 (27%), Positives = 41/114 (35%), Gaps = 8/114 (7%)

Query: 72  PQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPG-RPA 130
           P+Q  R    G     + PS        + +  PA P   +RPP        P PG +  
Sbjct: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG-GPPQPGPGPQRQ 477

Query: 131 GLHRSREPRPQ-----DGTPPPVDTPPRTARPRPAFTP-RPVVGSERPRQEQLR 178
           G    + P PQ      G  PP  +P     P P   P +P   +  P Q Q R
Sbjct: 478 GPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGR 531


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 58.9 bits (141), Expect = 2e-09
 Identities = 74/232 (31%), Positives = 92/232 (39%), Gaps = 64/232 (27%)

Query: 2   VPTCGENAASCRSGSHFPPAARGRLP-GETLSPSPRAAALPPLQQRPP--GAPGALGRPK 58
           +P   +  AS   GSH    + G LP G   S  P   A PP QQRPP  G P   G P 
Sbjct: 418 LPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQP---AGPPAQQRPPPQGGPPQPG-PG 473

Query: 59  PVSRGPRAGLREWPQ-QPWRPG---PLGAPLQDRAPS----------------------- 91
           P  +GP    R  PQ Q    G   P G+PL  R PS                       
Sbjct: 474 PQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQS 533

Query: 92  ---AHVPGS--ASRPTATPAPPRCSRRPP----TTTVSRVAP---SPGRPAGLHRSREPR 139
              A  PG+  A+RP A+P+P R    PP     T+VS  AP   S   P G  R   P+
Sbjct: 534 RPVAGGPGAPPAARPPASPSPQR-QAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592

Query: 140 PQDG----------------TPPPVDTPPRTARPRPAFTPRPVVGSERPRQE 175
              G                T PP    PR + P PA  P+P + +++P Q+
Sbjct: 593 KPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQL-AQKPSQD 643



 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 50/159 (31%), Positives = 60/159 (37%), Gaps = 14/159 (8%)

Query: 32  SPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAG---LREWPQQPWRPGPLGAP-LQD 87
           +PSP A  L     + P  P A  RP P    P+ G    R+ P    RP P G   L  
Sbjct: 436 TPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSG 495

Query: 88  RAPSA--HVPGSASRPTATPAPPRCSRRPPTTTVSR----VAPSPGRPAGLHRSREPRPQ 141
             P A   +P     PT+ P  P     PPT    R    VA  PG P        P PQ
Sbjct: 496 LGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQ 555

Query: 142 DGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRGP 180
               PP  T  +T+   PA    P      P  +Q +GP
Sbjct: 556 RQAGPPQAT-RQTSVSGPA---PPKASGAPPGGQQRQGP 590



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 57/157 (36%), Positives = 65/157 (41%), Gaps = 31/157 (19%)

Query: 19  PPAARG---RLPGETLSPS-PRAAALPPLQ-----QRP----PGAPGALGRPKPVSRGPR 65
           PPA      RLP  T +P  P + A PP Q      RP    PGAP A   P   S   +
Sbjct: 498 PPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQ 557

Query: 66  AGLREWPQQPWRPGPL-----GAP---LQDRAPSAHVPGSASRPT--ATPAPPRCSRRPP 115
           AG  +  +Q    GP      GAP    Q + P    PG A  PT  A+ A P     PP
Sbjct: 558 AGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAG-PTRQASQAGPVPRTGPP 616

Query: 116 TTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPP 152
           TT   R  PS   PAG      P+PQ    P  D PP
Sbjct: 617 TTQQPR--PSGPGPAG-----RPKPQLAQKPSQDVPP 646



 Score = 38.1 bits (87), Expect = 0.004
 Identities = 42/140 (30%), Positives = 48/140 (34%), Gaps = 27/140 (19%)

Query: 3   PTCGENAAS--CRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPV 60
           PT G+   S     G   PPAAR        SPSP+  A PP   R     G    P   
Sbjct: 525 PTQGQGRQSRPVAGGPGAPPAAR-----PPASPSPQRQAGPPQATRQTSVSGPA--PPKA 577

Query: 61  SRGPRAGLREW--PQQPWRPGPLG--------------APLQDRAPSAHVPGSASRPTAT 104
           S  P  G +    PQ+P  PGP G               P   + P    PG A RP   
Sbjct: 578 SGAPPGGQQRQGPPQKP--PGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQ 635

Query: 105 PAPPRCSRRPPTTTVSRVAP 124
            A       PP  T +   P
Sbjct: 636 LAQKPSQDVPPPATAAAGGP 655



 Score = 30.4 bits (67), Expect = 0.86
 Identities = 31/114 (27%), Positives = 41/114 (35%), Gaps = 8/114 (7%)

Query: 72  PQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPG-RPA 130
           P+Q  R    G     + PS        + +  PA P   +RPP        P PG +  
Sbjct: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG-GPPQPGPGPQRQ 477

Query: 131 GLHRSREPRPQ-----DGTPPPVDTPPRTARPRPAFTP-RPVVGSERPRQEQLR 178
           G    + P PQ      G  PP  +P     P P   P +P   +  P Q Q R
Sbjct: 478 GPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGR 531


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 50/156 (32%), Positives = 62/156 (39%), Gaps = 17/156 (10%)

Query: 26  LPGETLSP-------SPRAAALPPLQQ--RPPGAPGALGRPKPVSRGPRAGLREWPQQPW 76
           LP   LSP       +P   ALPPLQ    PP +P       P  + P A      Q P+
Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 665

Query: 77  RPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSR 136
            P P        +P A  P S S    + APP  +  P      +V PSP     +  S 
Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP-----LQVPPSPPASPPMSPSA 720

Query: 137 EPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERP 172
            P PQ   PPP+  PP    P P  +P P+  S  P
Sbjct: 721 TPPPQ--APPPLAAPPLQVPPSPPASP-PMSPSATP 753



 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 49/142 (34%), Positives = 57/142 (40%), Gaps = 18/142 (12%)

Query: 19  PPAARGRLPGETL-SPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWR 77
           PPA+    P  T  S +P + A PPLQ  PP  P +   P   S  P          P  
Sbjct: 679 PPASPPVSPSATPPSQAPPSLAAPPLQV-PPSPPAS--PPMSPSATP---------PPQA 726

Query: 78  PGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSRE 137
           P PL AP     PS       S P+ATP P    R PP      +   P  PA L  S  
Sbjct: 727 PPPLAAPPLQVPPSPPASPPMS-PSATPPP----RVPPLLAAPPLQVPPSPPASLPMSPL 781

Query: 138 PRPQDGTPPPVDTPPRTARPRP 159
            +P    PP + TPP  A P P
Sbjct: 782 AKPPPQAPPALATPPLQALPSP 803



 Score = 43.9 bits (102), Expect = 7e-05
 Identities = 45/157 (28%), Positives = 53/157 (33%), Gaps = 4/157 (2%)

Query: 27  PGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQ 86
           P    SP    +A PP Q  PP A   L  P      P       P     P     PLQ
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ 767

Query: 87  -DRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTP 145
              +P A +P S        APP  +  P     S  A  PG+      +  P     TP
Sbjct: 768 VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 827

Query: 146 PPVDTPPRTARPRPAFTPRPVVGS--ERPRQEQLRGP 180
           PP   PP  A P     P P      + PR+    GP
Sbjct: 828 PP-QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 863



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 39/146 (26%), Positives = 48/146 (32%), Gaps = 12/146 (8%)

Query: 32  SPSPRAAALPPLQQRPPGAPGALGRPKP-----VSRGPRAGLREWPQQPWRPGPLGAPLQ 86
           +P P  A   PL   PP  P ++  P P     ++  P  GL   P  P    P  AP  
Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPX 624

Query: 87  DRAPSAHVPGSAS-----RPTATPAPPRCSRRPPTTTVSRVAPSPGRP--AGLHRSREPR 139
              P    P S        P ATP+P   +        +  +P P  P  A       P 
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684

Query: 140 PQDGTPPPVDTPPRTARPRPAFTPRP 165
                 PP   PP  A P     P P
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSP 710



 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 50/165 (30%), Positives = 59/165 (35%), Gaps = 24/165 (14%)

Query: 19  PPAARGRLPGETLSP----SPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQ 74
           PP+    LP   L+     +P A A PPLQ  P   P +     P S  P A L   P  
Sbjct: 769 PPSPPASLPMSPLAKPPPQAPPALATPPLQALP-SPPASFPGQAPFS--PSASL---PMS 822

Query: 75  PWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHR 134
           P    P  AP    AP   VP S   P A+P   +  RRPPT         P     L  
Sbjct: 823 PLATPPPQAPPVLAAPLLQVPPS---PPASPT-LQAPRRPPTPGPDTSVSGPRLTLAL-- 876

Query: 135 SREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRG 179
                   G PPP    P +    P         +  P  E+LRG
Sbjct: 877 ------APGPPPPPSRSPSSTLSGPDLAGHSSSATSTP--EELRG 913



 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 42/121 (34%), Positives = 48/121 (39%), Gaps = 18/121 (14%)

Query: 20  PAARGRLPGETLSPSPRAAALPPLQQRPP-----GAPGALGRPKPVSRGPRAGLREWPQQ 74
           PAAR   PG  L+P P  +  PP    P      GA GA+GR     R    G    P+ 
Sbjct: 17  PAARA--PG-LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73

Query: 75  PWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVS-RVAPSPGRPAGLH 133
             R GP       R+        ASRP   PA  R  R PP    S     SPGR +G  
Sbjct: 74  APRAGP------TRSAGTSSRNPASRP---PASGRGERAPPAKNTSPGPVSSPGRASGTT 124

Query: 134 R 134
           R
Sbjct: 125 R 125



 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 51/192 (26%), Positives = 60/192 (31%), Gaps = 40/192 (20%)

Query: 9   AASCRSGSHFPPAARG--RLPGETLSPSPR-----------------AAALPPLQQRPPG 49
           ++  RSG    P+ARG  R P     P P+                 A AL PL   P  
Sbjct: 250 SSPARSG----PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305

Query: 50  APGALG-RPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPP 108
            P   G + +PV     A        P  P PL  PL    PS   P S     + PA P
Sbjct: 306 TPSPSGTKARPVPPPDNAATPLPATLPPSP-PLATPLPLAPPSPSAPPSLQTLPSPPATP 364

Query: 109 RCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVG 168
                P  TT    AP               P   T PP+  P     P     P P+  
Sbjct: 365 PSQAPPSMTTPPMQAP---------------PSLQTIPPIQVPHSLTSPSLQAPPSPLAL 409

Query: 169 SERPRQEQLRGP 180
           S       L  P
Sbjct: 410 SSLQATTSLGSP 421



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 43/152 (28%), Positives = 54/152 (35%), Gaps = 21/152 (13%)

Query: 20  PAARGRLPGE-----TLSPSPRAAALP-PLQQRPPGAPGALGRPKPVSRGPRAGLREWPQ 73
           P+AR R P E       S S  +   P P  +R P A G L RP   S    A       
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT------ 247

Query: 74  QPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSR--VAPSPGRPAG 131
                 PL +P +    +   P + + P+        + RPP  T  R   AP+ G P  
Sbjct: 248 ------PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG-PLS 300

Query: 132 LHRSREPRPQDGTPPPVDTPPRTARPRPAFTP 163
                 P P      PV  P   A P PA  P
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLP 332



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 48/179 (26%), Positives = 65/179 (36%), Gaps = 26/179 (14%)

Query: 13  RSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSR-GP--RAGLR 69
           R+G         R P      S R    PP +   PG   + GR    +R GP  + GLR
Sbjct: 76  RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135

Query: 70  EWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRP 129
              ++    G      +  A SA     A R T+ P P       P+  ++R + + G  
Sbjct: 136 ISAEETVARGKATEAPKRSALSA----GARRDTSGPTP-----GTPSPAMARRSRAAGTE 186

Query: 130 AGLHRSREPRPQDGTPPPVDTPPR---------TARPRPAFTPRPVVGS--ERPRQEQL 177
            GL R   P P     PP + P +         T  P PA   RP  G   +RP    L
Sbjct: 187 VGLPR---PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 42/132 (31%), Positives = 51/132 (38%), Gaps = 23/132 (17%)

Query: 32  SPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAP-LQDRAP 90
           +P+ RA  L  L  RPPG+P    RP P            P  P     LGA     R P
Sbjct: 16  TPAARAPGL--LTPRPPGSP----RPPP------------PVTPAALRVLGAAGAVGRKP 57

Query: 91  SAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDT 150
            A   G     T   + PR        T SR  P+   PA     R P  ++ +P PV +
Sbjct: 58  LAERAGGIGGATIPESAPRAGPTRSAGTSSR-NPASRPPASGRGERAPPAKNTSPGPVSS 116

Query: 151 PPR---TARPRP 159
           P R   T RP P
Sbjct: 117 PGRASGTTRPGP 128



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 41/146 (28%), Positives = 47/146 (32%), Gaps = 20/146 (13%)

Query: 39  ALPPLQQRPPGAPGALGRPKPV----------SRGPRAGLREWPQQPWRPGPLGAP--LQ 86
           A PPLQ     A   L  P  +          S  P+A L      P       AP  LQ
Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524

Query: 87  DRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREP--RPQDGT 144
               S   P   + P+  P P + +  P TT      P P  P  L     P   P   T
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA-PCPLQAPPSPLTTPPPET 583

Query: 145 P-----PPVDTPPRTARPRPAFTPRP 165
           P     PP   PP  A P     P P
Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPSP 609


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 59/209 (28%), Positives = 67/209 (32%), Gaps = 35/209 (16%)

Query: 3   PTCGENAASCRSGSHFPPAAR---GRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKP 59
           P    N      GS  PP      G  P     P      +PP    PP  PGA G   P
Sbjct: 217 PPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPP 276

Query: 60  VSRGPRAGLREWPQQ---PWRPGPLGAPLQDRAPSAH------------VPGSASRPTAT 104
            +  P AG          P+ PG +  P   +   AH             PGS  +P   
Sbjct: 277 SAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPR 336

Query: 105 PAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPP---------PVDTPP--- 152
           P P      PP   +    P  G P G      P    G PP         P   PP   
Sbjct: 337 PPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGY 396

Query: 153 -RTARPRPAFTPRPVVGSERPRQEQLRGP 180
            R   P P  TPRP V    P +  LRGP
Sbjct: 397 QRGPLPPPRPTPRPPV----PPRGPLRGP 421



 Score = 29.6 bits (65), Expect = 1.5
 Identities = 32/131 (24%), Positives = 40/131 (30%), Gaps = 16/131 (12%)

Query: 54  LGRPKPVSRG--PRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAP---- 107
           L    P+S+   P     + P  P  P P+ + L    P   +P   S P   P P    
Sbjct: 195 LAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALP 254

Query: 108 ---PRCSRRPPTT-------TVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARP 157
              P     PP           S   P  G P   H    P P  G P P  +  + A  
Sbjct: 255 PGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHH 314

Query: 158 RPAFTPRPVVG 168
            P     P  G
Sbjct: 315 GPHGLGHPHAG 325


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 56.2 bits (134), Expect = 1e-08
 Identities = 56/160 (35%), Positives = 66/160 (41%), Gaps = 19/160 (11%)

Query: 9    AASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPV-SRGPRAG 67
            A S  S S     A     G   SPSP+ A  PP    PP   G    P P  +  P A 
Sbjct: 910  ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT-PPSPKGGPATPSPKWAPTPPAA 968

Query: 68   LREWPQQ-PWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSP 126
                P+  P  P P GAP     P A  P S     ATP+ P+ +  PP  T     PSP
Sbjct: 969  TPPSPKGGPATPSPKGAP----TPPAATPPSPKGGPATPS-PKGAPTPPAVT----PPSP 1019

Query: 127  -GRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRP 165
             G PA       P P+  + PP  TPP + +  PA TP P
Sbjct: 1020 KGSPAA-----TPFPKGASTPPAATPP-SPKGSPAATPLP 1053



 Score = 56.2 bits (134), Expect = 1e-08
 Identities = 58/192 (30%), Positives = 67/192 (34%), Gaps = 44/192 (22%)

Query: 6    GENAASCRSGSHFPPAARGRLP-GETLSPSPRAAALPPLQQRP-----PGAPGALGRPKP 59
            G  A+    G+  PPAA    P G   +PSP+ A  PP    P     P  P   G P P
Sbjct: 929  GIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP 988

Query: 60   VSR---GPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPT 116
             +     P+ G       P  P P GAP     P+   P     P ATP P   S  P  
Sbjct: 989  PAATPPSPKGG-------PATPSPKGAPTP---PAVTPPSPKGSPAATPFPKGASTPPAA 1038

Query: 117  T-------------------TVSRVAPSP-GRPAGLHRSREPRPQDGTPPPVDTPPRTAR 156
            T                   T +   PSP G PA       P P   TPP     P T  
Sbjct: 1039 TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPS 1098

Query: 157  PR-----PAFTP 163
            P+     PA TP
Sbjct: 1099 PKGAPMPPAATP 1110



 Score = 56.2 bits (134), Expect = 1e-08
 Identities = 55/167 (32%), Positives = 67/167 (40%), Gaps = 17/167 (10%)

Query: 6    GENAASCRSGSHFPPAARGRLP-GETLSPSPRAAALPP--LQQRPPGAPGALGRPKPVSR 62
            G  A     G+  PPAA    P G   +PSP+ A  PP      P G+P A   PK  S 
Sbjct: 975  GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034

Query: 63   GPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRV 122
             P A     P  P +  P   PL   AP+     +A+ P+    P   S +   T  +  
Sbjct: 1035 PPAA----TPPSP-KGSPAATPLPKGAPTT---PAATLPSPKGGPATPSLKGAPTPPAAT 1086

Query: 123  APSP-GRPAGLHRSREPRPQDGTPPP----VDTPPRTARP-RPAFTP 163
             PSP G PA       P P   TPP     + TPP    P  PA TP
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP 1133



 Score = 53.9 bits (128), Expect = 7e-08
 Identities = 48/167 (28%), Positives = 59/167 (35%), Gaps = 19/167 (11%)

Query: 6    GENAASCRSGSHFPPAARGRLP-GETLSPSPRAAALPPLQQRP--------PGAPGALGR 56
            G  A     G+  PPAA    P G   +PSP+ A +PP    P        P   GA   
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128

Query: 57   PKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPT 116
            P      P+ GL         P P GAP    A      G  + P    AP   +  PP+
Sbjct: 1129 PAATPPSPKGGLA-------TPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181

Query: 117  TTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTP 163
                   PSP        +  P P+ G   P    P+ A   PA TP
Sbjct: 1182 PKGGLATPSPKGAPTTPAATPPSPKGGLATP---SPKGAPTTPAATP 1225



 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 50/166 (30%), Positives = 58/166 (34%), Gaps = 15/166 (9%)

Query: 6    GENAASCRSGSHFPPAARGRLP--GETLSPSPRAAALPPLQQ--RPPGAPGALGRPKPVS 61
            G  A     G+  PPA     P      +P P+ A+ PP      P G+P A   PK   
Sbjct: 998  GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAP 1057

Query: 62   RGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSR 121
              P A L      P  P   GAP     P A  P S     ATP+P      P  T  S 
Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAP----TPPAATPPSPKGGPATPSPKGAPMPPAATPPS- 1112

Query: 122  VAPSPGRPAGLHRSREPRPQDGTPPP----VDTPPRTARPRPAFTP 163
              P  G     H+     P    P P       PP+ A   PA TP
Sbjct: 1113 --PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156



 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 44/154 (28%), Positives = 57/154 (37%), Gaps = 14/154 (9%)

Query: 19   PPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPW-- 76
            PP+ +G L     +P P+ A   P    PP   G L  P P  +G        P  P   
Sbjct: 1133 PPSPKGGLA----TPPPKGAPTTPAAT-PPSPKGGLATPPP--KGAPTTPAATPPSPKGG 1185

Query: 77   --RPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHR 134
               P P GAP    A      G  + P+   AP   +  PP+       PSP        
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1245

Query: 135  SREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVG 168
            +  P P+ G   P   PP+ A   PA TP  + G
Sbjct: 1246 ATPPSPKGG---PATPPPKGAPTPPAATPPSLKG 1276



 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 53/158 (33%), Positives = 61/158 (38%), Gaps = 18/158 (11%)

Query: 19   PPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKP--VSRGPRAGLREWPQQPW 76
            PP+ +G L     +PSP+ A   P    PP   G L  P P      P A        P 
Sbjct: 1202 PPSPKGGLA----TPSPKGAPTTPAAT-PPSPKGGLATPSPKGAPTTPAATPPSPKGGPA 1256

Query: 77   RPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSP-GRPAGLHRS 135
             P P GAP     P A  P S     ATP P + +  P   T     PSP G PA     
Sbjct: 1257 TPPPKGAP----TPPAATPPSLKGGLATP-PHKGAPNPAVVT----PPSPKGGPATSPPK 1307

Query: 136  REPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPR 173
              P P   TPP     P T  P+ A TP P V    P+
Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTP-PAVTPPSPK 1344



 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 44/159 (27%), Positives = 56/159 (35%), Gaps = 20/159 (12%)

Query: 15   GSHFPPAARGRLP--GETLSPSPRAAALPPLQQRP-----PGAPGALGRPKPVSR---GP 64
            G+  PPAA    P      +P P+ A   P    P     P  P   G P P +     P
Sbjct: 1031 GASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP 1090

Query: 65   RAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAP 124
            + G       P  P P GAP+   A      G  + P    AP   +  PP+       P
Sbjct: 1091 KGG-------PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATP 1143

Query: 125  SPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTP 163
             P        +  P P+ G   P   PP+ A   PA TP
Sbjct: 1144 PPKGAPTTPAATPPSPKGGLATP---PPKGAPTTPAATP 1179



 Score = 50.4 bits (119), Expect = 8e-07
 Identities = 42/142 (29%), Positives = 54/142 (38%), Gaps = 21/142 (14%)

Query: 32   SPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPS 91
            S SP+ A   P  +  P +P   G P P +  P             P P G P       
Sbjct: 915  SSSPKKARATPAPKGIPASPSPKGAPTPPAATP-------------PSPKGGPATPSPKW 961

Query: 92   AHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSP-GRPAGLHRSREPRPQDGTPPPVDT 150
            A  P +A+ P+    P   S +   T  +   PSP G PA       P P+    PP  T
Sbjct: 962  APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPA------TPSPKGAPTPPAVT 1015

Query: 151  PPRTARPRPAFTPRPVVGSERP 172
            PP + +  PA TP P   S  P
Sbjct: 1016 PP-SPKGSPAATPFPKGASTPP 1036



 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 52/197 (26%), Positives = 72/197 (36%), Gaps = 51/197 (25%)

Query: 14  SGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSR--GPRA----- 66
           SG+    +++G L     SPSP   ++ P  +RPP   G+ G   P+     P +     
Sbjct: 775 SGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEAS 834

Query: 67  ----------GLREWP---QQPWRPGPLGAPLQDRAPSAHVPGSASRPT----------- 102
                     G ++ P     P  P P GAP     PSA  P S    T           
Sbjct: 835 FLPENSLSFQGSKDSPATTHSPTPPSPKGAP----TPSAVTPLSPKGVTLPPKETPTPSV 890

Query: 103 ----------ATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPP 152
                     ATPAP +      T++  + A +   P G+  S  P P+    PP  TPP
Sbjct: 891 VNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS--PSPKGAPTPPAATPP 948

Query: 153 R----TARPRPAFTPRP 165
                 A P P + P P
Sbjct: 949 SPKGGPATPSPKWAPTP 965



 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 50/174 (28%), Positives = 63/174 (36%), Gaps = 20/174 (11%)

Query: 19   PPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRP 78
            PP+ +G L       +P  A + P    P G P A   PK     P A        P  P
Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTP--PSPKGGP-ATSPPKGAPTPPAATPPSPKGSPGTP 1327

Query: 79   GPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRS--- 135
             P GAP     P A  P S       PA    S+  PTT  S+  P+P      H+    
Sbjct: 1328 PPKGAP----TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383

Query: 136  -REPRPQDG--TPPPVDTP------PRTARPRPAFTPRPVVGSERPRQEQLRGP 180
               P P+ G   P P   P      P + +  PA TP    G+  P +  L  P
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA-TPVTREGAATPSKGDLTPP 1436



 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 51/197 (25%), Positives = 68/197 (34%), Gaps = 31/197 (15%)

Query: 6    GENAASCRSGSHFPPAARGRLP-GETLSPSPRAAALPPLQQRP----------------- 47
            G  A S   G+  PPAA    P G   +P P+ A  PP    P                 
Sbjct: 1299 GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG 1358

Query: 48   -PGAPGALGRPKPVSRGP--RAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTAT 104
             P  P +   P P +  P  + G    P  P R   + +P  D    A +P S  +  AT
Sbjct: 1359 GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418

Query: 105  P-------APPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARP 157
            P        P +    PP  T   +  +P   A       P  +     P  TPP    P
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP 1478

Query: 158  RPAFTPRPVVGSERPRQ 174
             PA  P+ V  S  P++
Sbjct: 1479 -PA--PKQVATSSSPKK 1492



 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 33/128 (25%), Positives = 47/128 (36%), Gaps = 6/128 (4%)

Query: 42  PLQQRPPGAPGALGRPKPVSRGPRA--GLREWPQQPWRPGPLGAPLQDRAPSAHVPGSAS 99
           P     P  P   G P P +  P +  G+   P++   P  +  P     P+   P  A 
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909

Query: 100 RPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDG--TPPP--VDTPPRTA 155
             + T + P+ +R  P       +PSP        +  P P+ G  TP P    TPP   
Sbjct: 910 ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT 969

Query: 156 RPRPAFTP 163
            P P   P
Sbjct: 970 PPSPKGGP 977



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 52/195 (26%), Positives = 72/195 (36%), Gaps = 24/195 (12%)

Query: 3    PTCGENAASCRSGSHFPPAARG-RLPGETLSPSPRAAALPPLQQRPPGAPGALG-RPKPV 60
            P   E AA+   G   PPA     L     + +P+     P  +  P  P      PK  
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP 1478

Query: 61   SRGPRAGLREWPQQ-PWRPGPLGAP-LQDRAPSA--HVPGSASR------PTAT------ 104
                +      P++ P  P P+GAP L    PS+   VP + S       PTAT      
Sbjct: 1479 PAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKT 1538

Query: 105  PAP--PRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPR---TARPRP 159
            PA   P+ +  PP  TV     +P  P        P  ++ + PP  TP        P+ 
Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598

Query: 160  AFTPRPVVGSERPRQ 174
               P P V S  P++
Sbjct: 1599 LLIP-PAVTSPSPKE 1612



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 45/159 (28%), Positives = 60/159 (37%), Gaps = 21/159 (13%)

Query: 20   PAARGRLPGETLSPSPRAAALPPLQQRPPGAPGA--LGRPKPVSRGPRAGLREWPQQPWR 77
            P     LP   +  SP+     P  +R P AP A  L +  P +  P+  L         
Sbjct: 1499 PMGAPTLPA-VIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALI-------- 1549

Query: 78   PGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTT-TVSRVAPSPGR----PAGL 132
            P  +  P   + P+   P  A    ATP+    S  P  T +  + APSP      PA  
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAP---ATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVT 1606

Query: 133  HRSRE--PRPQDGTPPPVDTPPRTARPRPAFTPRPVVGS 169
              S +  P P   TPP  +  P T  P+   T  PV  S
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPS 1645



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 48/176 (27%), Positives = 67/176 (38%), Gaps = 23/176 (13%)

Query: 9    AASCRSGSHFPPAARG--RLPGETLS-----PSPRAAALPPLQQRPPGAPGALGRPKPVS 61
            A S   G    P+++G   LP  T       P+P+  A     ++ P  P  +G P   +
Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA 1507

Query: 62   RGPRAGLREWPQQPWRP----GPLGAPLQDRAPSAHVPGSASRPTA--------TPAPPR 109
              P +  +E P  P        P    L  + P+   P  A  P A        TPA P 
Sbjct: 1508 VIPSSP-KEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPT 1566

Query: 110  CSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQD-GTPPPVDTP-PRTARPRPAFTP 163
              +  P T  S+ A SP           P P++   PP V +P P+ A   PA TP
Sbjct: 1567 -PKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 42/152 (27%), Positives = 52/152 (34%), Gaps = 14/152 (9%)

Query: 19   PPAARGRLPGETLS-PSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWR 77
            PPA     P +T + P+P+ A   P  +     P     P      P       P     
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT--PSTYKGAPSPKELLIPPAVTS 1607

Query: 78   PGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGL---HR 134
            P P  AP     P A  P S  +  ATPAP      PP T  S +  SP  PA +     
Sbjct: 1608 PSPKEAP----TPPAVTPPSPEKGPATPAPKGTPTSPPVTP-SSLKDSPTSPASVTCKMG 1662

Query: 135  SREPRPQDGTPP---PVDTPPRTARPRPAFTP 163
            +  P+   G P    P         P P  TP
Sbjct: 1663 ATVPQASKGLPAKKGPTALKEVLVAPAPESTP 1694



 Score = 33.9 bits (76), Expect = 0.077
 Identities = 39/169 (23%), Positives = 65/169 (38%), Gaps = 20/169 (11%)

Query: 9    AASCRSGSHFPPAARGRLPGET---------LSPSPRAAAL--PPLQQRPPGAPGALGRP 57
            + +C+ G+  P A++G LP +          ++P+P +  +   P ++ P     +   P
Sbjct: 1656 SVTCKMGATVPQASKG-LPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP 1714

Query: 58   KPVSRGPRA-GLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPT 116
             P+   P A    + P     P PL    +D + +A    ++  P    APP      P 
Sbjct: 1715 -PICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPL 1773

Query: 117  TTVS--RVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTP 163
            T  +  +V P P   +       P      P PV T P    P+  F P
Sbjct: 1774 TAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLP----PKQQFLP 1818



 Score = 33.1 bits (74), Expect = 0.13
 Identities = 25/76 (32%), Positives = 30/76 (39%), Gaps = 1/76 (1%)

Query: 31   LSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAP 90
            L+PSP    LPP QQ  P +PG +         P       P  P  P   G P Q    
Sbjct: 1802 LAPSP-VPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLV 1860

Query: 91   SAHVPGSASRPTATPA 106
            +   P SA  P  TP+
Sbjct: 1861 NMPTPKSAGIPVPTPS 1876



 Score = 29.3 bits (64), Expect = 1.9
 Identities = 23/89 (25%), Positives = 32/89 (35%), Gaps = 11/89 (12%)

Query: 95  PGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSRE---PRPQDGTPPPVDTP 151
           PG    P  +PAP +C    P +  ++ +P P          E   P+   GT  P+ T 
Sbjct: 41  PGPTLPPPCSPAPQQC----PLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTA 96

Query: 152 PRTARPRPAFTPRPVVGSERPRQEQLRGP 180
           P      P F P  +     P    L  P
Sbjct: 97  PEA----PTFLPNLIGPPISPAALALASP 121


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 55.5 bits (132), Expect = 2e-08
 Identities = 68/207 (32%), Positives = 74/207 (35%), Gaps = 42/207 (20%)

Query: 6   GENAASCRSGSH---FPPAARGR------LPGETLSPSPRAAALPP-------LQQRPP- 48
           GE  A    GS    FP   RGR      +PG    P P     PP          RPP 
Sbjct: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPL 241

Query: 49  GAPGALGRPKPVSRG----------PRAGLRE-----WPQQPWRPGPLGAPLQDRAPSAH 93
           G PG  G P P   G          P  G R      +P QP+   PLG PL    P   
Sbjct: 242 GPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG-PLPP-GPPPP 299

Query: 94  VPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPR 153
           VPG    P   P PP+    PP        P P  P G   +  P P    PPP   PP 
Sbjct: 300 VPGYG--PPPGPPPPQQGPPPPP---GPFPPRPPGPLGPPLTLAPPPHLPGPPP-GAPPP 353

Query: 154 TARPRPAFTPRPVVGSERPRQEQLRGP 180
                PAF P P   S  P  +  RGP
Sbjct: 354 APHVNPAFFP-PPTNSGMPTSDS-RGP 378



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 45/149 (30%), Positives = 52/149 (34%), Gaps = 38/149 (25%)

Query: 27  PGETLSPS----PRAAALPPLQQRPPGAP--------------------GALGRPKPVSR 62
           PG+ L P     P     PP     PG P                    G    P P  +
Sbjct: 255 PGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQ 314

Query: 63  GPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRR--PPTTTVS 120
           GP      +P +P  PGPLG PL   AP  H+PG    P A P  P  +    PP T   
Sbjct: 315 GPPPPPGPFPPRP--PGPLGPPL-TLAPPPHLPGPP--PGAPPPAPHVNPAFFPPPT--- 366

Query: 121 RVAPSPGRPAGLHRSREPRPQDGTPPPVD 149
               + G P    R   P    G PPP D
Sbjct: 367 ----NSGMPTSDSRGPPPTDPYGRPPPYD 391


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
           sapiens]
          Length = 406

 Score = 54.7 bits (130), Expect = 4e-08
 Identities = 49/166 (29%), Positives = 61/166 (36%), Gaps = 32/166 (19%)

Query: 20  PAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPR-AGLREWPQQ---- 74
           P    R P   + P P  A +PP+   PPG+     R  PV  GPR A +  WP      
Sbjct: 250 PPMPPRPPMVPMPPRPPIAPMPPMAPVPPGS-----RMAPVPPGPRMAPVPPWPPMAPVP 304

Query: 75  PWRP------GPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGR 128
           PW P      GP  AP+    P A VP         P PP  +  PP   ++ + P P  
Sbjct: 305 PWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPM-APLPPGPPMAPLPPGP-- 361

Query: 129 PAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTP-----RPVVGS 169
                      P    PP    PPR+  P     P      PV+ S
Sbjct: 362 --------PMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINS 399



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 32/110 (29%), Positives = 35/110 (31%), Gaps = 12/110 (10%)

Query: 72  PQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAG 131
           P+ P  P P   P     P    P  A  P   P PP  SR  P     R+AP P  P  
Sbjct: 242 PRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPG-SRMAPVPPGPRMAPVPPWP-- 298

Query: 132 LHRSREPRPQDGTPP-PVDTPPRTARPRPAFTPRPVVGSERPRQEQLRGP 180
                   P    PP P   P  T  P     P P +    P     R P
Sbjct: 299 --------PMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVP 340



 Score = 32.3 bits (72), Expect = 0.23
 Identities = 24/88 (27%), Positives = 29/88 (32%), Gaps = 5/88 (5%)

Query: 83  APLQDRAPSAHVPGSASRPTATPAPPRCSR-----RPPTTTVSRVAPSPGRPAGLHRSRE 137
           AP  D A   H+     RP   P PP   R      PP   ++ + P    P G   +  
Sbjct: 226 APALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPV 285

Query: 138 PRPQDGTPPPVDTPPRTARPRPAFTPRP 165
           P      P P   P     P P   P P
Sbjct: 286 PPGPRMAPVPPWPPMAPVPPWPPMAPVP 313


>gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 350

 Score = 53.9 bits (128), Expect = 7e-08
 Identities = 56/179 (31%), Positives = 67/179 (37%), Gaps = 40/179 (22%)

Query: 8   NAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRP---KPVSRGP 64
           ++A+  + S FPP      PG    PS RAA    L+  P  AP  L R     P   G 
Sbjct: 41  SSAAAAASSSFPP------PGFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGA 94

Query: 65  RAGLR-------------------EWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATP 105
            AG R                    W +   RPGP   PLQ R+   H     + P ATP
Sbjct: 95  LAGSRLRAAAAAAHDQEAAAPTGRRWRR---RPGP-SPPLQPRSRHPHTRYPRAVPEATP 150

Query: 106 APPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPR 164
                  RPP  T  R    PG  +    +R   P +  PP  D  PR   PRP   PR
Sbjct: 151 L------RPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRA--PRPGDHPR 201



 Score = 35.4 bits (80), Expect = 0.027
 Identities = 28/96 (29%), Positives = 34/96 (35%), Gaps = 6/96 (6%)

Query: 19  PPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRP 78
           PP  R R       P  R++  P   + P  A    G P+P  R PR G         R 
Sbjct: 154 PPGTRPRAKSR---PGCRSSPFPARSRTPGEAGPPRGDPRP--RAPRPGDHPRRSPALRE 208

Query: 79  GP-LGAPLQDRAPSAHVPGSASRPTATPAPPRCSRR 113
            P L  P   R       G  + P   P PP C+ R
Sbjct: 209 TPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCATR 244


>gi|148727370 immediate early response 5-like [Homo sapiens]
          Length = 404

 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 41/116 (35%), Positives = 49/116 (42%), Gaps = 8/116 (6%)

Query: 33  PSPRAAALPPLQQRPPGAPGALGR-PKPVSRGPRAGL--REWPQQPWRPGP--LGAPLQD 87
           P+PR  A       P G  GAL   P   +  P  G   R  P +P +PGP  L  PL  
Sbjct: 132 PAPRGCAAAAAAGAPAGGAGALSELPGCAALQPPHGAPHRGQPLEPLQPGPAPLPLPLPP 191

Query: 88  RAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVA-PSPGRPAGLHRSREPRPQD 142
            AP+A  P     P A  APP  +  PP    S  A P+P    G +R   P P D
Sbjct: 192 PAPAALCPRDPRAPAACSAPPGAA--PPAAAASPPASPAPASSPGFYRGAYPTPSD 245


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 38/125 (30%), Positives = 45/125 (36%), Gaps = 13/125 (10%)

Query: 41  PPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASR 100
           PP+   PP  P   G+P P   GP   L  W QQ  +P P   P    A S  +P   + 
Sbjct: 473 PPMGMMPPPPPPPSGQPPPPPSGP---LPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNT 529

Query: 101 PTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPA 160
            T T +    S  P     +  A SPG P             G P  V  PP    P P 
Sbjct: 530 TTTTTSAGTGSIPPWQQQQAAAAASPGAP----------QMQGNPTMVPLPPGVQPPLPP 579

Query: 161 FTPRP 165
             P P
Sbjct: 580 GAPPP 584



 Score = 34.3 bits (77), Expect = 0.059
 Identities = 44/185 (23%), Positives = 56/185 (30%), Gaps = 28/185 (15%)

Query: 14  SGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSR-------GPRA 66
           SG    P A    P    +  P  + +   Q RPP         +P          GP  
Sbjct: 333 SGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGG 392

Query: 67  GLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSP 126
           G   +P     P P         P  H P     P   P PP  ++ P         P P
Sbjct: 393 GPHSFPH----PLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPP--GHHGPPP 446

Query: 127 ------GRPAG-----LHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQE 175
                   P G     LH+ +   P    PPP+   P    P     P P  G   P Q+
Sbjct: 447 MDQYLGSTPVGSGVYRLHQGKGMMP----PPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQ 502

Query: 176 QLRGP 180
           Q + P
Sbjct: 503 QQQQP 507



 Score = 34.3 bits (77), Expect = 0.059
 Identities = 37/167 (22%), Positives = 52/167 (31%), Gaps = 7/167 (4%)

Query: 17  HFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPW 76
           H  P+  G   G  +  +P     PP   +PP  P   G   P   GP    +     P 
Sbjct: 399 HPLPSLTGGHGGHPMQHNPNGP--PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPV 456

Query: 77  RPGPL----GAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGL 132
             G      G  +    P   +P     P+  P PP     PP     +  P P  P+  
Sbjct: 457 GSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSS 516

Query: 133 HRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRG 179
             S  P P         T   T    P +  +    +  P   Q++G
Sbjct: 517 MASSTPLPWQQNTTTTTTSAGTG-SIPPWQQQQAAAAASPGAPQMQG 562



 Score = 29.6 bits (65), Expect = 1.5
 Identities = 38/139 (27%), Positives = 47/139 (33%), Gaps = 44/139 (31%)

Query: 30  TLSPSPRAAALPPLQQR------PPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGA 83
           T + S    ++PP QQ+       PGAP   G P  V   P         QP  P P GA
Sbjct: 531 TTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGV-------QP--PLPPGA 581

Query: 84  PLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDG 143
           P                    P PP     PP  +   + P  G     H S     +D 
Sbjct: 582 P-------------------PPPPP-----PPPGSAGMMIPPRGGDGPSHES-----EDF 612

Query: 144 TPPPVDTPPRTARPRPAFT 162
             P V  P R  + RP +T
Sbjct: 613 PRPLVTLPGRQPQQRPWWT 631


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 38/125 (30%), Positives = 45/125 (36%), Gaps = 13/125 (10%)

Query: 41  PPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASR 100
           PP+   PP  P   G+P P   GP   L  W QQ  +P P   P    A S  +P   + 
Sbjct: 473 PPMGMMPPPPPPPSGQPPPPPSGP---LPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNT 529

Query: 101 PTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPA 160
            T T +    S  P     +  A SPG P             G P  V  PP    P P 
Sbjct: 530 TTTTTSAGTGSIPPWQQQQAAAAASPGAP----------QMQGNPTMVPLPPGVQPPLPP 579

Query: 161 FTPRP 165
             P P
Sbjct: 580 GAPPP 584



 Score = 36.2 bits (82), Expect = 0.016
 Identities = 42/130 (32%), Positives = 47/130 (36%), Gaps = 31/130 (23%)

Query: 30  TLSPSPRAAALPPLQQR------PPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGA 83
           T + S    ++PP QQ+       PGAP   G P  V   P         QP  P P GA
Sbjct: 531 TTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGV-------QP--PLPPGA 581

Query: 84  PLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGR-PAGLHRSREPRPQD 142
           P     P    PGSA    A P PP     PP    S      G   AG+       P  
Sbjct: 582 P---PPPPPPPPGSAGMMYAPPPPP-----PPPMDPSNFVTMMGMGVAGM-------PPF 626

Query: 143 GTPPPVDTPP 152
           G PP    PP
Sbjct: 627 GMPPAPPPPP 636



 Score = 34.3 bits (77), Expect = 0.059
 Identities = 44/185 (23%), Positives = 56/185 (30%), Gaps = 28/185 (15%)

Query: 14  SGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSR-------GPRA 66
           SG    P A    P    +  P  + +   Q RPP         +P          GP  
Sbjct: 333 SGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGG 392

Query: 67  GLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSP 126
           G   +P     P P         P  H P     P   P PP  ++ P         P P
Sbjct: 393 GPHSFPH----PLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPP--GHHGPPP 446

Query: 127 ------GRPAG-----LHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQE 175
                   P G     LH+ +   P    PPP+   P    P     P P  G   P Q+
Sbjct: 447 MDQYLGSTPVGSGVYRLHQGKGMMP----PPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQ 502

Query: 176 QLRGP 180
           Q + P
Sbjct: 503 QQQQP 507



 Score = 34.3 bits (77), Expect = 0.059
 Identities = 37/167 (22%), Positives = 52/167 (31%), Gaps = 7/167 (4%)

Query: 17  HFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPW 76
           H  P+  G   G  +  +P     PP   +PP  P   G   P   GP    +     P 
Sbjct: 399 HPLPSLTGGHGGHPMQHNPNGP--PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPV 456

Query: 77  RPGPL----GAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGL 132
             G      G  +    P   +P     P+  P PP     PP     +  P P  P+  
Sbjct: 457 GSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSS 516

Query: 133 HRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQEQLRG 179
             S  P P         T   T    P +  +    +  P   Q++G
Sbjct: 517 MASSTPLPWQQNTTTTTTSAGTG-SIPPWQQQQAAAAASPGAPQMQG 562


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
            potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 60/189 (31%), Positives = 70/189 (37%), Gaps = 35/189 (18%)

Query: 3    PTCGENAASCRSGSHFPPAARGRLPGET------LSPSPRAAALPPLQQRPPGAPGALGR 56
            P+ G  A +     HF  A  G L          L P  R+         PPGA G LG 
Sbjct: 895  PSAGVAATTIAGFGHFHKALGGSLSSSDSPLLTPLQPGARSPQAAQPSPAPPGARGGLGL 954

Query: 57   PK------PVSRGPRAGLREWPQQPWR------PGPLGA----PLQDRAPS--AHVPGSA 98
            P+      P SR P +   +  Q P         GPL      P Q   PS  A   G A
Sbjct: 955  PEHFLPPPPSSRSPSSSPGQLGQPPGELSLGLATGPLSTPETPPRQPEPPSLVAGASGGA 1014

Query: 99   SRPTATP----APPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRT 154
            S    TP    +PP  S  PP T  S    +P R +G H S    P   +PPP   P R 
Sbjct: 1015 SPVGFTPRGGLSPPGHSPGPPRTFPS----APPRASGSHGSL-LLPPASSPPPPQVPQR- 1068

Query: 155  ARPRPAFTP 163
             R  P  TP
Sbjct: 1069 -RGTPPLTP 1076


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 47/153 (30%), Positives = 60/153 (39%), Gaps = 10/153 (6%)

Query: 27  PGETLSPSPRAAALP---PLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGA 83
           PG+   P P+    P   P   +P G P   G     SR P  G  + P       P G 
Sbjct: 260 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP-PGKPQGPPPQGGNQPQGP 318

Query: 84  PLQDRAPSAHVPGSASRPTATPAPPRCSRRPPT-TTVSRVAPS-PGRPAGLHRSREPRPQ 141
           P     P    P   ++P   P P +    PP   + SR A S PG+P G  +     PQ
Sbjct: 319 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQ 378

Query: 142 DGTPPPVDTPPRTARPRPAFTPRPVVGSERPRQ 174
            G PPP    P+  +  PA  P+   G  RP Q
Sbjct: 379 -GPPPPAGGNPQQPQAPPAGQPQ---GPPRPPQ 407



 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 49/170 (28%), Positives = 65/170 (38%), Gaps = 33/170 (19%)

Query: 27  PGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPG-PLGAPL 85
           PG+   P P+    P   Q PP  PG     KP    P+ G +  PQ P  PG P G P 
Sbjct: 54  PGKPQGPPPQGGNQP---QGPPPPPG-----KPQGPPPQGGNK--PQGPPPPGKPQGPPP 103

Query: 86  Q-DRA---------PSAHVPGSASRPTATPAPPRCSRRPPTTTVSRV--APSPGRPAG-- 131
           Q D++         P    P   ++P   P PP   + PP    ++    P PG+P G  
Sbjct: 104 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 163

Query: 132 ------LHRSREPRPQDGTPPPVDTPPRTARPRPAFTPR--PVVGSERPR 173
                    SR P  +   PPP         P P   P+  P  G  +P+
Sbjct: 164 PQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 213



 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 44/159 (27%), Positives = 56/159 (35%), Gaps = 12/159 (7%)

Query: 19  PPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPK------PVSRGPRA--GLRE 70
           PP   G  P     P  +    PP     P  P   G+P+        SR PR+  G  +
Sbjct: 60  PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ 119

Query: 71  WPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPT-TTVSRVAPS-PGR 128
            P       P G P     P    P   ++P   P P +    PP     SR + S PG+
Sbjct: 120 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGK 179

Query: 129 PAGLHRSREPRPQDGTPPP--VDTPPRTARPRPAFTPRP 165
           P G       +PQ   PPP     PP     +P   P P
Sbjct: 180 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 218



 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 43/149 (28%), Positives = 54/149 (36%), Gaps = 14/149 (9%)

Query: 27  PGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGA--- 83
           PG+   P P+    P   Q PP  PG    P P         R  P +P  P P G    
Sbjct: 198 PGKPQGPPPQGGNKP---QGPP-PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQP 253

Query: 84  ---PLQDRAPSAHVPGSASRPTATPAPPRCSRRPPT-TTVSRVAPS-PGRPAGLHRSREP 138
              P     P    P   ++P   P P +    PP   + SR + S PG+P G       
Sbjct: 254 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN 313

Query: 139 RPQDGTPPP--VDTPPRTARPRPAFTPRP 165
           +PQ   PPP     PP     +P   P P
Sbjct: 314 QPQGPPPPPGKPQGPPPQGGNKPQGPPPP 342



 Score = 43.9 bits (102), Expect = 7e-05
 Identities = 43/149 (28%), Positives = 53/149 (35%), Gaps = 14/149 (9%)

Query: 27  PGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGA--- 83
           PG+   P P+    P   Q PP  PG    P P         R  P +P  P P G    
Sbjct: 136 PGKPQGPPPQGGNKP---QGPP-PPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQP 191

Query: 84  ---PLQDRAPSAHVPGSASRPTATPAPPRCSRRPPT-TTVSRVAPS-PGRPAGLHRSREP 138
              P     P    P   ++P   P P +    PP     S+ A S PG+P G       
Sbjct: 192 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN 251

Query: 139 RPQDGTPPP--VDTPPRTARPRPAFTPRP 165
           +PQ   PPP     PP     +P   P P
Sbjct: 252 QPQGPPPPPGKPQGPPPQGGNKPQGPPPP 280



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 35/136 (25%), Positives = 48/136 (35%), Gaps = 9/136 (6%)

Query: 27  PGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGA--- 83
           PG+   P P+  +     + PPG P     P P       G    P +P  P P G    
Sbjct: 280 PGKPQGPPPQGGSKSRSSRSPPGKPQG---PPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 336

Query: 84  --PLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQ 141
             P     P    P   S+  +  +PP   + PP    +     P  PAG +  +   P 
Sbjct: 337 QGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNN-PQGPPPPAGGNPQQPQAPP 395

Query: 142 DGTPPPVDTPPRTARP 157
            G P     PP+  RP
Sbjct: 396 AGQPQGPPRPPQGGRP 411



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 40/138 (28%), Positives = 47/138 (34%), Gaps = 15/138 (10%)

Query: 34  SPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPG---PLGAPLQDRAP 90
           SP   A  P    P G     G P P  +         PQ P   G   P G P     P
Sbjct: 28  SPSLIAGNPQGAPPQGGNKPQGPPSPPGK---------PQGPPPQGGNQPQGPPPPPGKP 78

Query: 91  SAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPS-PGRPAGLHRSREPRPQDGTPPP-- 147
               P   ++P   P P +    PP    SR   S PG+P G       +PQ   PPP  
Sbjct: 79  QGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 138

Query: 148 VDTPPRTARPRPAFTPRP 165
              PP     +P   P P
Sbjct: 139 PQGPPPQGGNKPQGPPPP 156



 Score = 33.9 bits (76), Expect = 0.077
 Identities = 32/100 (32%), Positives = 40/100 (40%), Gaps = 17/100 (17%)

Query: 27  PGETLSPSPRAAALP---PLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQ----PWRPG 79
           PG+   P P+    P   P   +P G P   G     +R P    +  PQQ    P  P 
Sbjct: 322 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPP 381

Query: 80  PL--GAPLQDRAPSAHVPGSASRPTATPAPPRCSR--RPP 115
           P   G P Q +AP       A +P   P PP+  R  RPP
Sbjct: 382 PPAGGNPQQPQAP------PAGQPQGPPRPPQGGRPSRPP 415



 Score = 31.2 bits (69), Expect = 0.50
 Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 10/121 (8%)

Query: 3   PTCGENAASCRSGS---HFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKP 59
           P  G  + S RS       PP   G  P     P  +    PP     P  P   G  KP
Sbjct: 288 PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG--KP 345

Query: 60  VSRGPRAGLREWPQQPWRPGPLGAPLQD----RAPSAHVPGSASRPTATPA-PPRCSRRP 114
               P+ G +    +     P G P Q+    + P     G+  +P A PA  P+   RP
Sbjct: 346 QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 405

Query: 115 P 115
           P
Sbjct: 406 P 406


>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
          Length = 1006

 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 42/112 (37%), Positives = 49/112 (43%), Gaps = 20/112 (17%)

Query: 22  ARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPL 81
           A G L G  L+  P   A  P  + P  AP     P+P SRGPR GL   PQ+P  PGP 
Sbjct: 876 AHGLLLGAPLA-GPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEP-PPGP- 932

Query: 82  GAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRV-APSPGRPAGL 132
                        P  A+ P A P PP     PP+ +   V  PS G PA L
Sbjct: 933 ------------PPSPAAAPEAVPPPP----APPSYSDKGVQTPSKGTPAPL 968



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 44/162 (27%), Positives = 61/162 (37%), Gaps = 15/162 (9%)

Query: 19  PPAARGRLPGETLSP-SPRAAALPPLQQRPPGAP-----GALGRPKPVSRGPRAGLREWP 72
           PP      PG+   P +PR++  P  ++   G       GA GR    S+ P + + +  
Sbjct: 618 PPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAE 677

Query: 73  QQPWRPGPLGAPLQ-DRAPSAHVPGSASRPTATPAPPRCSRRP--PTTTVSRVAPSPGRP 129
             P R       ++  R  +  V       +    PPR    P  P    +  APSP  P
Sbjct: 678 DDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAP 737

Query: 130 AGLHRSRE--PRPQDGTPPPVDTPPRTARPRPAFTPRPVVGS 169
               R R+       G PPP   PP    P P  +PRP  GS
Sbjct: 738 VRTRRRRKLYELHAAGAPPP---PPPGHAPAPE-SPRPGSGS 775



 Score = 31.6 bits (70), Expect = 0.38
 Identities = 28/86 (32%), Positives = 30/86 (34%), Gaps = 23/86 (26%)

Query: 81  LGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRP 140
           LGAPL      A  P     P+  PAP               +P PG       SR PR 
Sbjct: 881 LGAPLAGPGVEARTPADRG-PSPAPAPA-------------ASPQPG-------SRGPR- 918

Query: 141 QDGTPPPVDTPPRTARPRPAFTPRPV 166
            DG  P    PP    P PA  P  V
Sbjct: 919 -DGLGPEPQEPPPGPPPSPAAAPEAV 943



 Score = 30.4 bits (67), Expect = 0.86
 Identities = 29/94 (30%), Positives = 36/94 (38%), Gaps = 25/94 (26%)

Query: 95  PGSASRPTATPAPPRCSRR-------------PPTTTVSRVAPSPGRPA-------GLHR 134
           PG A+ P  +PA P  +RR             PP       AP   RP        GL  
Sbjct: 724 PGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAP 783

Query: 135 SREPRP-QDGTPPPVDTPPRTARPRPAFTPRPVV 167
           +R P P  DG   P+D   +  RP P   P P +
Sbjct: 784 ARSPGPAADG---PIDLSKKPRRPLPG-APAPAL 813


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 55/188 (29%), Positives = 63/188 (33%), Gaps = 28/188 (14%)

Query: 19  PPAARGRLPGETLSPSPRAAALPPL----QQRPPGAPGALGRPKPVSRGPRAGLREWPQQ 74
           PP   G        P  +    PP      Q PP  PG   RP P       G    P +
Sbjct: 60  PPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGK 119

Query: 75  PWRPGPLGAPLQDRAPSAHVPGSASRPT---------ATPAPPRCSRRPPTT-TVSRVAP 124
           P RP P G     R P    PG   RP            P P +    PP     SR A 
Sbjct: 120 PERPPPQGGNQSHRPPPP--PGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSAR 177

Query: 125 S-PGRPAGLHRSREPRPQDGTPP--PVDTPPRTARP---------RPAFTPRPVVGSERP 172
           S PG+P G  +    +PQ   PP  P   PP    P         +P   P P  G   P
Sbjct: 178 SPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRPP 237

Query: 173 RQEQLRGP 180
           R  Q + P
Sbjct: 238 RPAQGQQP 245



 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 47/151 (31%), Positives = 56/151 (37%), Gaps = 28/151 (18%)

Query: 45  QRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRP--- 101
           QRPP  PG    P P       G    P +P    P G   Q + P  H PG   RP   
Sbjct: 48  QRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGN-QSQGPPPH-PGKPERPPPQ 105

Query: 102 -----TATPAPPRCSRRPPT---TTVSRVAPSPGR-----PAGLHRSREPRPQ----DGT 144
                  TP PP    RPP        R  P PG+     P G ++S+ P P     +G 
Sbjct: 106 GGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGP 165

Query: 145 PPPVDTPPRTARPRPAFTPRPVVGSERPRQE 175
           PP      R+AR  P     P      P+QE
Sbjct: 166 PPQEGNKSRSARSPPGKPQGP------PQQE 190



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 40/145 (27%), Positives = 48/145 (33%), Gaps = 17/145 (11%)

Query: 20  PAARGRLPGETLSPSPRAAALPPLQ-----QRPPGAPGALGRPKPVSRGPRAGLREWPQQ 74
           P  +G    +   P P     PP Q      RPP  PG   RP P       G    P +
Sbjct: 102 PPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGK 161

Query: 75  PWRPGPL--GAPLQDRAPSAHVPG----SASRPTATPAPPRCSRRPPT--TTVSRVAPSP 126
           P  P P         R+P     G      ++P   P P +    PP         AP  
Sbjct: 162 PEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPA 221

Query: 127 GRPAGL----HRSREPRPQDGTPPP 147
           G+P G        R PRP  G  PP
Sbjct: 222 GKPQGPPPPPQGGRPPRPAQGQQPP 246



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 42/159 (26%), Positives = 55/159 (34%), Gaps = 23/159 (14%)

Query: 15  GSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQ 74
           G+  PP    R P +  + S           RPP  PG   RP P       G    P +
Sbjct: 112 GTPPPPGKPERPPPQGGNQS----------HRPPPPPGKPERPPPQGGNQSQGPPPHPGK 161

Query: 75  PWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHR 134
           P  P P      +++ SA  P     P     PP+     P        P    PAG + 
Sbjct: 162 PEGPPPQEG---NKSRSARSP-----PGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNP 213

Query: 135 SREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERPR 173
            +   P  G P     PP+  RP     PRP  G + P+
Sbjct: 214 QQPQAPPAGKPQGPPPPPQGGRP-----PRPAQGQQPPQ 247



 Score = 36.2 bits (82), Expect = 0.016
 Identities = 43/140 (30%), Positives = 52/140 (37%), Gaps = 36/140 (25%)

Query: 58  KPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPP-RCSRRPPT 116
           KP  R P+ G      QP RP P         P    P   ++    P PP +   RPP 
Sbjct: 35  KPEGRRPQGG-----NQPQRPPP-----PPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQ 84

Query: 117 --TTVSRVAPSPGRPAGLHRSREPRPQ-----DGTPPPVDTPPRTARPRP-----AFTPR 164
                    P PG+P        P PQ      GTPPP   P +  RP P     +  P 
Sbjct: 85  GGNQSQGPPPHPGKP------ERPPPQGGNQSQGTPPP---PGKPERPPPQGGNQSHRPP 135

Query: 165 PVVGS-ERPRQE---QLRGP 180
           P  G  ERP  +   Q +GP
Sbjct: 136 PPPGKPERPPPQGGNQSQGP 155


>gi|169171345 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 249

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 54/163 (33%), Positives = 68/163 (41%), Gaps = 21/163 (12%)

Query: 19  PPAARGRLPGETLSPSPRAAALPPLQQRPPG--------APGALGRPKPVSRGPRAGLRE 70
           PPA R RL  +  SP+P A A PPL Q P G         PG  G  +  +RG R G R 
Sbjct: 11  PPAGRERLQNKAWSPAP-APARPPLNQPPGGKALSTRALQPG--GALEAGTRGGREGHRR 67

Query: 71  WPQQPWRPGPLGAPLQDR-APSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRP 129
             Q P    P G+PL +     A  P S +R        R + R     + +V P    P
Sbjct: 68  LRQPPTPSAPPGSPLHEGFLLIALFPSSQNR-------HRSAGRGLAGRLQQVRPGAAGP 120

Query: 130 AG-LHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSER 171
            G L     PRP  G+ P   +PP   RP        V G++R
Sbjct: 121 RGRLPWVTGPRPA-GSLPAAQSPPPAERPGRDAAGARVCGTQR 162


>gi|169172205 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 249

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 54/163 (33%), Positives = 68/163 (41%), Gaps = 21/163 (12%)

Query: 19  PPAARGRLPGETLSPSPRAAALPPLQQRPPG--------APGALGRPKPVSRGPRAGLRE 70
           PPA R RL  +  SP+P A A PPL Q P G         PG  G  +  +RG R G R 
Sbjct: 11  PPAGRERLQNKAWSPAP-APARPPLNQPPGGKALSTRALQPG--GALEAGTRGGREGHRR 67

Query: 71  WPQQPWRPGPLGAPLQDR-APSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRP 129
             Q P    P G+PL +     A  P S +R        R + R     + +V P    P
Sbjct: 68  LRQPPTPSAPPGSPLHEGFLLIALFPSSQNR-------HRSAGRGLAGRLQQVRPGAAGP 120

Query: 130 AG-LHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSER 171
            G L     PRP  G+ P   +PP   RP        V G++R
Sbjct: 121 RGRLPWVTGPRPA-GSLPAAQSPPPAERPGRDAAGARVCGTQR 162


>gi|169170949 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 249

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 54/163 (33%), Positives = 68/163 (41%), Gaps = 21/163 (12%)

Query: 19  PPAARGRLPGETLSPSPRAAALPPLQQRPPG--------APGALGRPKPVSRGPRAGLRE 70
           PPA R RL  +  SP+P A A PPL Q P G         PG  G  +  +RG R G R 
Sbjct: 11  PPAGRERLQNKAWSPAP-APARPPLNQPPGGKALSTRALQPG--GALEAGTRGGREGHRR 67

Query: 71  WPQQPWRPGPLGAPLQDR-APSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRP 129
             Q P    P G+PL +     A  P S +R        R + R     + +V P    P
Sbjct: 68  LRQPPTPSAPPGSPLHEGFLLIALFPSSQNR-------HRSAGRGLAGRLQQVRPGAAGP 120

Query: 130 AG-LHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSER 171
            G L     PRP  G+ P   +PP   RP        V G++R
Sbjct: 121 RGRLPWVTGPRPA-GSLPAAQSPPPAERPGRDAAGARVCGTQR 162


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 51/173 (29%), Positives = 65/173 (37%), Gaps = 32/173 (18%)

Query: 19  PPAARGRLP-----GETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQ 73
           PP A    P     G  L+   R++ + P    PP AP  LG P     GP+ G    P 
Sbjct: 269 PPPAEFSYPVDNQRGSGLAGPKRSSVVSP--SHPPPAP-PLGSPP----GPKPGFAPPPA 321

Query: 74  QPWRPGPL-GAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGL 132
            P  P P+ G P          PG       TP PP     PP    +   P P  PA  
Sbjct: 322 PPPPPPPMIGIPPPPPPVGFGSPG-------TPPPPSPPSFPPHPDFAAPPPPPPPPAAD 374

Query: 133 HRSREP----RPQDGTPPPVDTPPRTARPRPAFT--------PRPVVGSERPR 173
           + +  P    +P  G PPP   PP    P P FT        P P+  + +P+
Sbjct: 375 YPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPK 427


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 48/144 (33%), Positives = 51/144 (35%), Gaps = 8/144 (5%)

Query: 14   SGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVS--RGPRAGLREW 71
            SG   P  A GR P +   P P     PP    P GAPG  G P  V   RG   G    
Sbjct: 1238 SGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRG-EPGDCGL 1296

Query: 72   PQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGR--P 129
            P  P  PGP G P     P          P   P P      P       +   PGR  P
Sbjct: 1297 PGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGP 1356

Query: 130  AGLHRSREPRPQDGTPPPVDTPPR 153
             GL     PR + G P  VD  PR
Sbjct: 1357 TGL---PGPRGEPGPPADVDDCPR 1377



 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 50/157 (31%), Positives = 56/157 (35%), Gaps = 23/157 (14%)

Query: 19  PPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRP 78
           PP  RG L G      PR     P  + P G PG LG   P  R   AG       P  P
Sbjct: 769 PPGKRG-LSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGF------PGVP 821

Query: 79  GPLGAPLQDRAPSAHVPGSASRP--TATPAPPRCSRR-----PPTTTVSRVAPS-PGRPA 130
           GP G   +  AP   +PG    P    +P  P    +     PP     +  P  PGRP 
Sbjct: 822 GPPGHSCERGAPG--IPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPG 879

Query: 131 -----GLHRSREPRPQDGTP-PPVDTPPRTARPRPAF 161
                GL     P   DG P PP    PR     P F
Sbjct: 880 AHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGF 916



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 30/89 (33%), Positives = 37/89 (41%), Gaps = 7/89 (7%)

Query: 47  PPGAPGALGRPKPVSRG--PRAGLREWPQQPWRPGPLGAP-LQDRAPSAHVPGSASRPTA 103
           PPG PG LGRP     G     G + +P  P  PG  G P   D AP    PG    P  
Sbjct: 386 PPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGK--PGKPGSP-G 442

Query: 104 TPAPPRCSRRPPTTTVSRVAPSPGRPAGL 132
            P  P     P ++ +     +PG P G+
Sbjct: 443 LPGAPGLQGLPGSSVIYCSVGNPG-PQGI 470



 Score = 34.7 bits (78), Expect = 0.045
 Identities = 52/187 (27%), Positives = 62/187 (33%), Gaps = 29/187 (15%)

Query: 6    GENAASCRSGSHF--PPAARG--RLPGETLSP-SPRAAALPPLQQR-PPGAPGALGRPKP 59
            G+      SG H   PP   G   L GE   P SP  +   P  ++ PPG PG+ G P P
Sbjct: 1184 GQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGP 1243

Query: 60   VSRGPRAGLREWPQ--------QPWRPGPLGAP-----------LQDRAPSAHVPGSASR 100
                 RA  ++ P          P   GP GAP           L+       +PG    
Sbjct: 1244 AGATGRAP-KDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPG- 1301

Query: 101  PTATPAPPRCSRRPPTTTVSRVAPSPG--RPAGLHRSREPRPQDGTPPPVDTPPRTARPR 158
            P   P PP     P            G   P G H    P  + G P P      T  P 
Sbjct: 1302 PPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPG 1361

Query: 159  PAFTPRP 165
            P   P P
Sbjct: 1362 PRGEPGP 1368



 Score = 34.3 bits (77), Expect = 0.059
 Identities = 55/209 (26%), Positives = 66/209 (31%), Gaps = 59/209 (28%)

Query: 16   SHF-PPAARGRLPGETLSPSPRAAA----LPPLQ-----QRPPGAPGALGRPKPVSRGPR 65
            SHF PP  +G  PG    P    A+    LP +Q        PG PG+ G P        
Sbjct: 1079 SHFGPPGPKGE-PGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGM 1137

Query: 66   AGLREWPQQPWRPGPLG-------------------------------------APLQDR 88
             GLR  P +   PGP G                                     + L D 
Sbjct: 1138 PGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDV 1197

Query: 89   APSAHV--------PGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRP 140
             P   V         G    P  +P  PR  + PP    S   P P    G  R+ +  P
Sbjct: 1198 GPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATG--RAPKDIP 1255

Query: 141  QDGTPPPVDTPPRTARPRPAFTPRPVVGS 169
              G PP    PP    PR A  P  + GS
Sbjct: 1256 DPG-PPGDQGPPGPDGPRGAPGPPGLPGS 1283



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 28/82 (34%), Positives = 30/82 (36%), Gaps = 6/82 (7%)

Query: 15   GSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQ 74
            G   P  A G LPG      P     P L  R  G  G  G P P  R    G   +P  
Sbjct: 1386 GMRGPEGAMG-LPGMRGPSGPGCKGEPGLDGRR-GVDGVPGSPGPPGRKGDTGEDGYPGG 1443

Query: 75   PWRPGPLGAPLQDRAPSAHVPG 96
            P  PGP+G P     P    PG
Sbjct: 1444 PGPPGPIGDP----GPKGFGPG 1461



 Score = 32.7 bits (73), Expect = 0.17
 Identities = 51/192 (26%), Positives = 62/192 (32%), Gaps = 54/192 (28%)

Query: 15   GSHFPPAARGRLPGETLSPSPRAA-ALPPLQQRP--------PGAPGALGRP----KPVS 61
            GS   P  +G+ PG+   P P     LP L  RP        PG PG  G       P  
Sbjct: 846  GSPGAPGGKGQ-PGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGP 904

Query: 62   RGPRA--GLREWPQQPWRPGPLGAPLQDRAPS----AHVPG------------------- 96
            +GPR   G   +P +  +PG  G P     P     + +PG                   
Sbjct: 905  KGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGE 964

Query: 97   ----SASRPTATPAPP--------RCSRRPPTTTVSRVAPSPGRPAGLHRSREP--RPQD 142
                S       P PP        R  +  P     R  P    P G HR  EP  + Q 
Sbjct: 965  MAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRG-EPGEKGQP 1023

Query: 143  GTPPPVDTPPRT 154
            G P P   P  T
Sbjct: 1024 GPPGPPGPPGST 1035



 Score = 31.6 bits (70), Expect = 0.38
 Identities = 39/148 (26%), Positives = 46/148 (31%), Gaps = 12/148 (8%)

Query: 6    GENAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPR 65
            G++      G    P  +GR  GE     P     P   +  PG  G  G P P      
Sbjct: 981  GDDGFPGERGDKGTPGMQGRR-GE-----PGRYGPPGFHRGEPGEKGQPGPPGPPGPPGS 1034

Query: 66   AGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPS 125
             GLR +   P  PG  G P     P       A  P      P     PP       +P 
Sbjct: 1035 TGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPG 1094

Query: 126  -PGR-----PAGLHRSREPRPQDGTPPP 147
             PG        GL   + PR   G P P
Sbjct: 1095 CPGHFGASGEQGLPGIQGPRGSPGRPGP 1122



 Score = 30.8 bits (68), Expect = 0.66
 Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 7/93 (7%)

Query: 41  PPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPG--SA 98
           PP    P G  G LG P P+      G+R     P   G  G    D+ P+  VPG    
Sbjct: 66  PPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKG----DKGPTG-VPGFPGL 120

Query: 99  SRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAG 131
                 P PP    +P  +  +     PG P G
Sbjct: 121 DGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGG 153



 Score = 30.0 bits (66), Expect = 1.1
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 2/60 (3%)

Query: 27  PGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQ--PWRPGPLGAP 84
           PG TL   P    L   ++   G PG +G P P  R   +G+    ++  P  PGP G P
Sbjct: 254 PGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDP 313



 Score = 27.3 bits (59), Expect = 7.3
 Identities = 42/178 (23%), Positives = 51/178 (28%), Gaps = 30/178 (16%)

Query: 6   GENAASCRSGSHFPPAARGRLPGETLSPSPRAA----ALPPLQQRPPGAPGALGRPKPVS 61
           G +   C  G+  P   +G++ G      P+       L   +  P G PG  G P    
Sbjct: 454 GSSVIYCSVGNPGPQGIKGKV-GPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQG 512

Query: 62  RGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSR 121
                GL  W      PGP GA      P  H             PP          VSR
Sbjct: 513 SKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKH---------GASGPPGNKGAKGDMVVSR 563

Query: 122 VAPS------------PGRPAGLHRSREPRPQDGTPPPVD----TPPRTARPRPAFTP 163
           V               PG+P    R      +    PP D    TP     P P   P
Sbjct: 564 VKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPP 621



 Score = 26.9 bits (58), Expect = 9.5
 Identities = 27/94 (28%), Positives = 29/94 (30%), Gaps = 20/94 (21%)

Query: 15  GSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQ 74
           G H PP   G  PG    P P+            GAPG  G      R    G  E P  
Sbjct: 674 GRHGPPGFDGP-PGPKGFPGPQ------------GAPGLSGSDGHKGRPGTPGTAEIPGP 720

Query: 75  PWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPP 108
           P   G +G P              S P   P PP
Sbjct: 721 PGFRGDMGDP-------GFGGEKGSSPVGPPGPP 747


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 52/163 (31%), Positives = 57/163 (34%), Gaps = 24/163 (14%)

Query: 19  PPAARGRLPGETLSPSPRAAALPPL----QQRPPGAPGALGRPKPVSRGPRAGLREWPQQ 74
           PP+     PG    P P    LPP     +  PP  PG L  P     GP       P Q
Sbjct: 220 PPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQ 279

Query: 75  PWRPGPLGAPLQDRAPSAHVPGSASRPTA----TPA----PPRCSRRPPTTTVSRVAPSP 126
              P P    +   AP  H P S   P A     PA    PP     PPT+ V   AP  
Sbjct: 280 LPPPAP---GVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGV 336

Query: 127 GRPA-GLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPRPVVG 168
             PA G+H      P  G  PP    P    P P   P P  G
Sbjct: 337 HPPAPGVH-----PPAPGVHPPA---PGVHPPAPGVHPPPSAG 371



 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 50/157 (31%), Positives = 61/157 (38%), Gaps = 20/157 (12%)

Query: 19  PPAARGRLPGETLSPSPRAAALPP-LQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWR 77
           PP   G LP   + P+  A + PP   Q PP APG +  P PV   P +G+      P  
Sbjct: 252 PPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPG-VHPPAPVVHPPASGV-----HPPA 305

Query: 78  PGPLGAPLQDRAPSAHVPG-SASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPA-GLHRS 135
           PG     +   AP  H P      PT+   PP     PP   V   AP    PA G+H  
Sbjct: 306 PG-----VHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVH-- 358

Query: 136 REPRPQDGTPPPVDTPPRTARPRPAFTPRPVVGSERP 172
             P P    PP     P+     PA    P V  + P
Sbjct: 359 -PPAPGVHPPPSAGVHPQAPGVHPA---APAVHPQAP 391



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 50/197 (25%), Positives = 63/197 (31%), Gaps = 41/197 (20%)

Query: 2   VPTCGENAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVS 61
           +P  G   +        PP A G  P   +   P +   PP     P APG +  P P  
Sbjct: 264 MPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPG-VHPPAPGV 322

Query: 62  RGPRAGLREWPQQPWRPG--PLGAPLQDRAPSAHVPGSASRPTA--TPAPPRCSRRPPTT 117
             P +G+      P  PG  P    +   AP  H P     P A     PP     P   
Sbjct: 323 HPPTSGV-----HPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAP 377

Query: 118 TVSRVAP-----SPG-----------------RPAGLHRSR---EPRP------QDGTPP 146
            V   AP     +PG                 +P G+H S     P+P        G  P
Sbjct: 378 GVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHP 437

Query: 147 PVDTPPRTARPRPAFTP 163
           P   PP    P P+  P
Sbjct: 438 PTPMPPMLRPPLPSEGP 454



 Score = 35.4 bits (80), Expect = 0.027
 Identities = 32/116 (27%), Positives = 39/116 (33%), Gaps = 25/116 (21%)

Query: 45  QRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTAT 104
           ++PP  P     P  V R P   +   P +P  P  L  P                P   
Sbjct: 215 EKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPP---------------PPGGL 259

Query: 105 PAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPA 160
           P PP     PPT       P+P  P G  +   P P    P PV  PP +    PA
Sbjct: 260 PLPPM----PPT------GPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPA 305


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 42/149 (28%), Positives = 59/149 (39%), Gaps = 15/149 (10%)

Query: 28  GETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQD 87
           GE++ PS  + + PP+QQ  PG P A    +P     + G  + P QP     L  PL  
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPA---QQPGHEKSQPGPAKPPAQP---SGLTKPLAQ 344

Query: 88  RAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPP 147
           +  +   P      T  PA P    +PP        PS         S +P P+    PP
Sbjct: 345 QPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS---------SEQPGPKALAQPP 395

Query: 148 VDTPPRTARPRPAFTPRPVVGSERPRQEQ 176
                   +P PA  P   VG+ +P  +Q
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424



 Score = 47.8 bits (112), Expect = 5e-06
 Identities = 49/185 (26%), Positives = 66/185 (35%), Gaps = 45/185 (24%)

Query: 35  PRAAALPPLQQRPP------GAPG-----ALGRPKPVSRGPRAGLREWPQQPWRP--GPL 81
           P     PPLQQ+PP        PG       G PK +S      ++  P    +P  GP 
Sbjct: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPT 262

Query: 82  GAPLQDRAP-----------------------SAHVPGSASRPTATPAPPRCSRRPPTTT 118
             P  D A                           +P  +  P   P P +   + P   
Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHE 322

Query: 119 VSRVAPS--PGRPAGLHRSREPRPQDGTPPPVDTPPRTARP-----RPAFTPRPVVGSER 171
            S+  P+  P +P+GL +    +P  GT  P   PP T +P      PA  P    GSE+
Sbjct: 323 KSQPGPAKPPAQPSGLTKPLAQQP--GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380

Query: 172 PRQEQ 176
           P  EQ
Sbjct: 381 PSSEQ 385



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 48/164 (29%), Positives = 64/164 (39%), Gaps = 29/164 (17%)

Query: 25  RLPGETLSPSPRAA-ALPPLQQRPPGAPGA--LGRPKPVSRGPRAGLREWPQQPWRPGPL 81
           + PG T +P  +      P QQ  PG   A   G  KP S+ P  G  + P  P +PGP 
Sbjct: 432 KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP--GPAKPP--PQQPGPA 487

Query: 82  GAPLQDRA---PSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREP 138
             P Q      P +  PGS   P   P P +              PSP +P     ++ P
Sbjct: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAK--------------PSPQQPGS---TKPP 530

Query: 139 RPQDGTPPPVDTPPRTARPRPAFTPRPV--VGSERPRQEQLRGP 180
             Q G+  P    P  A+P    + +PV   GS +P Q     P
Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP 574



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 6/83 (7%)

Query: 82   GAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQ 141
            G       P++ +P  +   ++ PA PR   R  +  +S   P P  P        P P 
Sbjct: 2364 GETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP-----PPPPPPP 2418

Query: 142  DGTPPPVDTPPRTARPRPAFTPR 164
               PPP   PP T+ P+P   P+
Sbjct: 2419 PPPPPPPPLPPPTS-PKPTILPK 2440



 Score = 35.4 bits (80), Expect = 0.027
 Identities = 48/195 (24%), Positives = 74/195 (37%), Gaps = 54/195 (27%)

Query: 31   LSPSPRAAALPPLQQRPPGAPGALGR--------PKPVSRGPRAGLR-----EWPQ-QPW 76
            +SP P A  +P     PPG     G+        PKP  +  R  L      + P+ QP 
Sbjct: 862  MSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT 921

Query: 77   RP-----GPL---GAPLQDRA---------PSAHV---PGSASRPTATPAPPRCSRRPPT 116
             P     G L   GA +  +A         P  H    PG+  +    P+ P  S+ PP 
Sbjct: 922  TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981

Query: 117  TTVSRVAPSPGRPAGLHRSR--------EPRPQ----------DGTPPPV-DTPPRTARP 157
            +T  +  P+P +   + +          EP+ +          +  PPP+ D+   TA P
Sbjct: 982  ST-GQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040

Query: 158  RPAFTPRPVVGSERP 172
            + A  P  +  S +P
Sbjct: 1041 QKAVLPTKLEKSPKP 1055



 Score = 32.7 bits (73), Expect = 0.17
 Identities = 38/148 (25%), Positives = 50/148 (33%), Gaps = 25/148 (16%)

Query: 42   PLQQRPPGAPGALG---RPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSA 98
            P  Q P G+P       +P+P  R     +   P  P  P P   P     P   +P   
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431

Query: 99   S-RPTATPAPPRCSRRPPTTT-----------VSRVAPSPGRPAGLHRSREPRPQDGTPP 146
            S +PT  P        P TT             + V  S G P     +  P P    PP
Sbjct: 2432 SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPP---VPP 2488

Query: 147  PVDTPPR----TARP---RPAFTPRPVV 167
               + P     T RP   +P   P+PV+
Sbjct: 2489 KPSSIPSGLVFTHRPEPSKPPIAPKPVI 2516



 Score = 28.1 bits (61), Expect = 4.3
 Identities = 21/92 (22%), Positives = 35/92 (38%), Gaps = 4/92 (4%)

Query: 81   LGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRP 140
            +  P++++  + +     +     PA    S  P  +++    P+  RP     S +   
Sbjct: 2348 IALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSL----PAKPRPFFRSSSLDISA 2403

Query: 141  QDGTPPPVDTPPRTARPRPAFTPRPVVGSERP 172
            Q   PPP   PP    P P   P P   S +P
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP 2435


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 42/149 (28%), Positives = 59/149 (39%), Gaps = 15/149 (10%)

Query: 28  GETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRPGPLGAPLQD 87
           GE++ PS  + + PP+QQ  PG P A    +P     + G  + P QP     L  PL  
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPA---QQPGHEKSQPGPAKPPAQP---SGLTKPLAQ 344

Query: 88  RAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPP 147
           +  +   P      T  PA P    +PP        PS         S +P P+    PP
Sbjct: 345 QPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS---------SEQPGPKALAQPP 395

Query: 148 VDTPPRTARPRPAFTPRPVVGSERPRQEQ 176
                   +P PA  P   VG+ +P  +Q
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424



 Score = 47.8 bits (112), Expect = 5e-06
 Identities = 49/185 (26%), Positives = 66/185 (35%), Gaps = 45/185 (24%)

Query: 35  PRAAALPPLQQRPP------GAPG-----ALGRPKPVSRGPRAGLREWPQQPWRP--GPL 81
           P     PPLQQ+PP        PG       G PK +S      ++  P    +P  GP 
Sbjct: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPT 262

Query: 82  GAPLQDRAP-----------------------SAHVPGSASRPTATPAPPRCSRRPPTTT 118
             P  D A                           +P  +  P   P P +   + P   
Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHE 322

Query: 119 VSRVAPS--PGRPAGLHRSREPRPQDGTPPPVDTPPRTARP-----RPAFTPRPVVGSER 171
            S+  P+  P +P+GL +    +P  GT  P   PP T +P      PA  P    GSE+
Sbjct: 323 KSQPGPAKPPAQPSGLTKPLAQQP--GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380

Query: 172 PRQEQ 176
           P  EQ
Sbjct: 381 PSSEQ 385



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 48/164 (29%), Positives = 64/164 (39%), Gaps = 29/164 (17%)

Query: 25  RLPGETLSPSPRAA-ALPPLQQRPPGAPGA--LGRPKPVSRGPRAGLREWPQQPWRPGPL 81
           + PG T +P  +      P QQ  PG   A   G  KP S+ P  G  + P  P +PGP 
Sbjct: 432 KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP--GPAKPP--PQQPGPA 487

Query: 82  GAPLQDRA---PSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREP 138
             P Q      P +  PGS   P   P P +              PSP +P     ++ P
Sbjct: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAK--------------PSPQQPGS---TKPP 530

Query: 139 RPQDGTPPPVDTPPRTARPRPAFTPRPV--VGSERPRQEQLRGP 180
             Q G+  P    P  A+P    + +PV   GS +P Q     P
Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP 574



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 6/83 (7%)

Query: 82   GAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQ 141
            G       P++ +P  +   ++ PA PR   R  +  +S   P P  P        P P 
Sbjct: 2364 GETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP-----PPPPPPP 2418

Query: 142  DGTPPPVDTPPRTARPRPAFTPR 164
               PPP   PP T+ P+P   P+
Sbjct: 2419 PPPPPPPPLPPPTS-PKPTILPK 2440



 Score = 35.4 bits (80), Expect = 0.027
 Identities = 48/195 (24%), Positives = 74/195 (37%), Gaps = 54/195 (27%)

Query: 31   LSPSPRAAALPPLQQRPPGAPGALGR--------PKPVSRGPRAGLR-----EWPQ-QPW 76
            +SP P A  +P     PPG     G+        PKP  +  R  L      + P+ QP 
Sbjct: 862  MSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT 921

Query: 77   RP-----GPL---GAPLQDRA---------PSAHV---PGSASRPTATPAPPRCSRRPPT 116
             P     G L   GA +  +A         P  H    PG+  +    P+ P  S+ PP 
Sbjct: 922  TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981

Query: 117  TTVSRVAPSPGRPAGLHRSR--------EPRPQ----------DGTPPPV-DTPPRTARP 157
            +T  +  P+P +   + +          EP+ +          +  PPP+ D+   TA P
Sbjct: 982  ST-GQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040

Query: 158  RPAFTPRPVVGSERP 172
            + A  P  +  S +P
Sbjct: 1041 QKAVLPTKLEKSPKP 1055



 Score = 32.7 bits (73), Expect = 0.17
 Identities = 38/148 (25%), Positives = 50/148 (33%), Gaps = 25/148 (16%)

Query: 42   PLQQRPPGAPGALG---RPKPVSRGPRAGLREWPQQPWRPGPLGAPLQDRAPSAHVPGSA 98
            P  Q P G+P       +P+P  R     +   P  P  P P   P     P   +P   
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431

Query: 99   S-RPTATPAPPRCSRRPPTTT-----------VSRVAPSPGRPAGLHRSREPRPQDGTPP 146
            S +PT  P        P TT             + V  S G P     +  P P    PP
Sbjct: 2432 SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPP---VPP 2488

Query: 147  PVDTPPR----TARP---RPAFTPRPVV 167
               + P     T RP   +P   P+PV+
Sbjct: 2489 KPSSIPSGLVFTHRPEPSKPPIAPKPVI 2516



 Score = 28.1 bits (61), Expect = 4.3
 Identities = 21/92 (22%), Positives = 35/92 (38%), Gaps = 4/92 (4%)

Query: 81   LGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRP 140
            +  P++++  + +     +     PA    S  P  +++    P+  RP     S +   
Sbjct: 2348 IALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSL----PAKPRPFFRSSSLDISA 2403

Query: 141  QDGTPPPVDTPPRTARPRPAFTPRPVVGSERP 172
            Q   PPP   PP    P P   P P   S +P
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP 2435


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 47/166 (28%), Positives = 60/166 (36%), Gaps = 10/166 (6%)

Query: 3   PTCGENAASCRSGSHFPPAARGRLPGETLSPSPRAAAL---PPLQQRPPGAPGALGRPKP 59
           PT G+     R G   PP  +       +   P   +L   PP  ++PPG P     P  
Sbjct: 211 PTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTN 270

Query: 60  VSRGPRAGLREWPQQPWRPGPLG--APLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTT 117
            S  P    R        PGP+   AP    + S  +  +   P A   P R +  PP  
Sbjct: 271 ES-APELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPP 329

Query: 118 TV----SRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRP 159
            V    +R AP P  P  +H S  P      PPP  TP     P P
Sbjct: 330 PVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPP 375



 Score = 50.8 bits (120), Expect = 6e-07
 Identities = 49/148 (33%), Positives = 58/148 (39%), Gaps = 26/148 (17%)

Query: 33  PSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWP--QQPWRP--------GPLG 82
           PS RAAA      RPP    A GRP+  +   RA L E P  Q+P  P           G
Sbjct: 116 PSSRAAA-----PRPP-VSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTG 169

Query: 83  APLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQD 142
                 AP    PG  +    TP P   S+ P       + P+PG+   LH  RE  P  
Sbjct: 170 MKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQ--RLHPGREGPP-- 225

Query: 143 GTPPPVDTPP-----RTARPRPAFTPRP 165
             PPPV  PP     RT     +  P P
Sbjct: 226 -APPPVKPPPSPVNIRTGPSGQSLAPPP 252



 Score = 32.7 bits (73), Expect = 0.17
 Identities = 32/105 (30%), Positives = 38/105 (36%), Gaps = 7/105 (6%)

Query: 19  PPAARGRLPGETLSPSPRAAAL--PPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQP- 75
           P   RG  P    S SP   +   PP  + PP    A   P PV R    G R+ P  P 
Sbjct: 288 PGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRN---GARDAPPPPP 344

Query: 76  -WRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTV 119
            +R      P + + P       A  P   P P R   R   TTV
Sbjct: 345 PYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTV 389



 Score = 30.0 bits (66), Expect = 1.1
 Identities = 33/126 (26%), Positives = 42/126 (33%), Gaps = 15/126 (11%)

Query: 19  PPAARGRLPGETLSPS-PRAAALPPLQQR-------PPGAPGALGRPKPVSRGPRA---- 66
           PP    + PG    PS P   + P L QR        PG    L  P P S  P      
Sbjct: 251 PPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNR 310

Query: 67  ---GLREWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATPAPPRCSRRPPTTTVSRVA 123
                R+ P +   P P    +++ A  A  P    R   +  P R    PP +      
Sbjct: 311 PPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGP 370

Query: 124 PSPGRP 129
           P P  P
Sbjct: 371 PPPPPP 376


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.135    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,778,401
Number of Sequences: 37866
Number of extensions: 1099798
Number of successful extensions: 16197
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 650
Number of HSP's successfully gapped in prelim test: 1855
Number of HSP's that attempted gapping in prelim test: 6505
Number of HSP's gapped (non-prelim): 7454
length of query: 180
length of database: 18,247,518
effective HSP length: 96
effective length of query: 84
effective length of database: 14,612,382
effective search space: 1227440088
effective search space used: 1227440088
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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