Guide to the Human Genome
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Search of human proteins with 119226260

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|119226260 calcium homeostasis endoplasmic reticulum protein
[Homo sapiens]
         (916 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|119226260 calcium homeostasis endoplasmic reticulum protein [...  1951   0.0  
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]      105   1e-22
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               91   6e-18
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]           87   5e-17
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     87   9e-17
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]      86   1e-16
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           86   1e-16
gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]        86   2e-16
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          86   2e-16
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          86   2e-16
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          86   2e-16
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]     85   3e-16
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     85   4e-16
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ...    84   6e-16
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    82   2e-15
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    82   2e-15
gi|9558733 transformer-2 alpha [Homo sapiens]                          81   5e-15
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s...    80   9e-15
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    80   9e-15
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap...    79   2e-14
gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]     79   2e-14
gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]     79   2e-14
gi|50083281 KIAA1853 protein [Homo sapiens]                            79   2e-14
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        77   7e-14
gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]        76   2e-13
gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]     75   2e-13
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          75   3e-13
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    75   4e-13
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ...    74   5e-13
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         74   5e-13

>gi|119226260 calcium homeostasis endoplasmic reticulum protein
           [Homo sapiens]
          Length = 916

 Score = 1951 bits (5055), Expect = 0.0
 Identities = 916/916 (100%), Positives = 916/916 (100%)

Query: 1   MEMPLPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKDNPKFSFLFGGEFYSYYKCKL 60
           MEMPLPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKDNPKFSFLFGGEFYSYYKCKL
Sbjct: 1   MEMPLPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKDNPKFSFLFGGEFYSYYKCKL 60

Query: 61  ALEQQQLICKQQTPELEPAATMPPLPQPPLAPAAPIPPAQGAPSMDELIQQSQWNLQQQE 120
           ALEQQQLICKQQTPELEPAATMPPLPQPPLAPAAPIPPAQGAPSMDELIQQSQWNLQQQE
Sbjct: 61  ALEQQQLICKQQTPELEPAATMPPLPQPPLAPAAPIPPAQGAPSMDELIQQSQWNLQQQE 120

Query: 121 QHLLALRQEQVTAAVAHAVEQQMQKLLEETQLDMNEFDNLLQPIIDTCTKDAISAGKNWM 180
           QHLLALRQEQVTAAVAHAVEQQMQKLLEETQLDMNEFDNLLQPIIDTCTKDAISAGKNWM
Sbjct: 121 QHLLALRQEQVTAAVAHAVEQQMQKLLEETQLDMNEFDNLLQPIIDTCTKDAISAGKNWM 180

Query: 181 FSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHCQRKQARELLAALQKV 240
           FSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHCQRKQARELLAALQKV
Sbjct: 181 FSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHCQRKQARELLAALQKV 240

Query: 241 VVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYS 300
           VVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYS
Sbjct: 241 VVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYS 300

Query: 301 SVVQPVQLAFQQQIQTLKTQHEEFVTSLAQQQQQQQQQQQQLQMPQMEAEVKATPPPPAP 360
           SVVQPVQLAFQQQIQTLKTQHEEFVTSLAQQQQQQQQQQQQLQMPQMEAEVKATPPPPAP
Sbjct: 301 SVVQPVQLAFQQQIQTLKTQHEEFVTSLAQQQQQQQQQQQQLQMPQMEAEVKATPPPPAP 360

Query: 361 PPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPPNKPP 420
           PPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPPNKPP
Sbjct: 361 PPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPPNKPP 420

Query: 421 WFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPW 480
           WFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPW
Sbjct: 421 WFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPW 480

Query: 481 NNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPH 540
           NNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPH
Sbjct: 481 NNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPH 540

Query: 541 PHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPHHHPGHRMPHPGINE 600
           PHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPHHHPGHRMPHPGINE
Sbjct: 541 PHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPHHHPGHRMPHPGINE 600

Query: 601 HPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVK 660
           HPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVK
Sbjct: 601 HPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVK 660

Query: 661 LEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAK 720
           LEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAK
Sbjct: 661 LEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAK 720

Query: 721 MRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSR 780
           MRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSR
Sbjct: 721 MRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSR 780

Query: 781 SRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLG 840
           SRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLG
Sbjct: 781 SRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLG 840

Query: 841 EENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQYKGVGVALDDPYENYRRN 900
           EENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQYKGVGVALDDPYENYRRN
Sbjct: 841 EENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQYKGVGVALDDPYENYRRN 900

Query: 901 KSYSFIARMKARDECK 916
           KSYSFIARMKARDECK
Sbjct: 901 KSYSFIARMKARDECK 916


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score =  105 bits (263), Expect = 1e-22
 Identities = 146/545 (26%), Positives = 206/545 (37%), Gaps = 103/545 (18%)

Query: 358  PAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPG--GVQDPAAAGPRGPGP---HD 412
            P   P    AP  PP  +   S+PP Q        A G  G+  P   GPRGP P    +
Sbjct: 1725 PQARPGEGTAPLPPPGQKVGGSQPPFQGQREPGPHALGMSGLHGPNFPGPRGPAPPFPEE 1784

Query: 413  QIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWG-------- 464
             I  N  P   +  P A +G Q+ P    +    G PP+      S   + G        
Sbjct: 1785 NIASNDGP---RGPPPARFGAQKGPIPSLFSGQHGPPPYGDSRGPSPSYLGGPRGVAPSQ 1841

Query: 465  -EQRGDPGWNGQ--RDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPH 521
             E+R DP    +  +DAP+N    A   +QFEG      EQ P+ G +   PF+      
Sbjct: 1842 FEERKDPHGEKREFQDAPYNEVTGAP--AQFEGT-----EQAPFLGSRGGAPFQFGGQ-- 1892

Query: 522  FRGPFPPHQQHPQFNQPPHPHNFNRFPP--RFMQDDFPPRHPFE--RPPYPHRFDYPQGD 577
             R P     + P+   PP      R PP   F+    P    FE  R P+P++F+ P+G 
Sbjct: 1893 -RRPLLSQLKGPRGGPPPSQFGGQRGPPPGHFVGPRGPHPSQFETARGPHPNQFEGPRGQ 1951

Query: 578  FPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHP---DFGPPPHGFNGQPPHMRR--QGPP 632
             P  M  P      +     ++  P +   + P    FG    G  G  P   +  Q P 
Sbjct: 1952 APNFMPGPRGIQPQQFEDQRVHSPPRFTNQRAPAPLQFG----GLRGSAPFSEKNEQTPS 2007

Query: 633  --HINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAV 690
              H     P ++   P          PL++L  H   P   KD R     PPS    +A 
Sbjct: 2008 RFHFQGQAPQVMKPGP---------RPLLELPSHP--PQHRKD-RWEEAGPPSALSSSAP 2055

Query: 691  EAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKG-----QEKRNSGP------SRS 739
                  P  D    S  + +   +E+       R+R+      +EK    P      S  
Sbjct: 2056 G---QGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASED 2112

Query: 740  RSRSKSRGRSSSRSNS----------RSSKSSGSYSRSRSRSCSRS----------YSRS 779
            R R + RGR+ SR             R   SS  + R+R RS +R           + RS
Sbjct: 2113 RRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRS 2172

Query: 780  RSRSRSRSRS-------SRSRSRSQSRSRSKSYSPGRRRRSRSRS------PTPPSSAGL 826
            R RSR+R R         RSRSR + R +++    GR R+ RS+S      P P +S   
Sbjct: 2173 RERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRAS 2232

Query: 827  GSNSA 831
             + +A
Sbjct: 2233 DAGTA 2237



 Score = 33.5 bits (75), Expect = 0.93
 Identities = 41/191 (21%), Positives = 68/191 (35%), Gaps = 17/191 (8%)

Query: 334  QQQQQQQQLQMPQMEAEVKATPPPPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEA 393
            Q +++  +  +   +A V  TPP   PPP P P P  P        KP    P ++   A
Sbjct: 1236 QSEKKPSKYPLCSADAAVSTTPPGSPPPPPPLPEP--PVLKVLSSLKPAAPSPATAATTA 1293

Query: 394  PG---GVQDPAAAGPRGPGPHDQIPP---NKPPWFDQPHPVAPWGQQQPPEQPPYPHHQG 447
                      A++  +   P + I      K   FD      P      P++P      G
Sbjct: 1294 AAASTAASSTASSASKTASPLEHILQTLFGKKKSFDPSAREPPGSTAGLPQEPKTTAEDG 1353

Query: 448  GPPHCPPWNNSHEGMWGEQRGDPGWNGQR-DAPWNNQ----PDAAWNSQF--EGPWNSQH 500
             P   PP  +     +G+   D     +  D P++ +    P+ A+++Q    G  +   
Sbjct: 1354 VP--APPLLDPIVQQFGQFSKDKALEEEEDDRPYDPEEEYDPERAFDTQLVERGRRHEVE 1411

Query: 501  EQPPWGGGQRE 511
              P     +RE
Sbjct: 1412 RAPEAAAAERE 1422


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 90.5 bits (223), Expect = 6e-18
 Identities = 97/362 (26%), Positives = 126/362 (34%), Gaps = 69/362 (19%)

Query: 344 MPQMEAEVKATPPPPAPPPA---------PAPAPAIPPTTQPDDSKPPIQMPGSSEYEAP 394
           +P     V   PPPP PPP          P P   + P   P    PP  M    + E P
Sbjct: 309 LPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETP 368

Query: 395 GGVQDPAAAGPRGP-----GPHDQ---IPPNKPPWF---DQPHPVAPWGQQQPPEQPPYP 443
             +  P    P+ P      PH +   + P + P      QP P    G Q+ P  P +P
Sbjct: 369 RMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAV--GPQRFPGPPEFP 426

Query: 444 HHQGGPP----------------HCPPWNNSHEGMWGEQRGDPGWNG-----QRDAPWNN 482
            H  GP                   PP     +  +    G+P +       QR  P   
Sbjct: 427 QHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPP 486

Query: 483 QPDAAWNSQFEGPWNSQ----HEQPPWGGGQREPPFRMQRP--PHFRGPFPPHQQHPQFN 536
            P    NS    P  S        P +    ++P F  +RP  P  + P P    H  F+
Sbjct: 487 PPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILH--FS 544

Query: 537 QPPHPHNFNRFPPR--FMQ---DDFPPRH-------PFERP-PYPHRFDYPQGDFPAEMG 583
           QP         PPR  F+      F P H       P   P P PH+   PQ   P +  
Sbjct: 545 QPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQ---PQPQQPQQQP 601

Query: 584 PPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVP 643
           PP H P H+ PH    +H P   PQHP   PP H  +    H+    PP +    P   P
Sbjct: 602 PPQHQPPHQPPHQPPPQHQP--PPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRP 659

Query: 644 NV 645
           +V
Sbjct: 660 HV 661



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 101/393 (25%), Positives = 127/393 (32%), Gaps = 111/393 (28%)

Query: 304 QPVQLAFQQQI--QTLKTQHEEFVTSLAQQQQQQQQQQQQLQMPQMEAEVKATPPPPAPP 361
           QP++  FQ Q     L  QH    +       Q      QL+ P+M      TPPP  P 
Sbjct: 330 QPIRSLFQPQPLQPLLPVQHPHHPSP-----PQGMHMPPQLETPRM----MMTPPPVTPQ 380

Query: 362 P---------------APAPAPAIPPTTQPDDSKPPIQMPGSSEY--EAPGGVQDPAAAG 404
                            P   P +P  +QP  +  P + PG  E+    PG V +  +  
Sbjct: 381 QPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQP 440

Query: 405 PRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHH----QGGPPHCPP----WN 456
           PR P   DQ     PP    P  +   G+      P +P H    Q  PP  PP     N
Sbjct: 441 PRLP-LQDQWRAPPPPQDRDPFFLGVSGE------PRFPSHLFLEQRSPPPPPPPPTLLN 493

Query: 457 NSH----EGMWGEQRGDPGWNGQRDAP---------------------WNNQPDAAWNSQ 491
           +SH    +      +  P +N Q   P                       +QP +A    
Sbjct: 494 SSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRP 553

Query: 492 F-----------EGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPH 540
           F             P+   H QP   G    P      PPH   P  P QQ P  +QPPH
Sbjct: 554 FIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPP----LPPPHQPQPQQPQQQPPPQHQPPH 609

Query: 541 --PHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPHHHPGHRMPHPGI 598
             PH     PP   Q   PP+HP + PP                   HHH  H +  P  
Sbjct: 610 QPPHQ----PP--PQHQPPPQHPPQHPPQHQ----------------HHHHHHHLSVP-- 645

Query: 599 NEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGP 631
              PP      P F P       Q    R Q P
Sbjct: 646 --PPPLMPMSQPQFRPHVQTAQPQASSSRMQCP 676



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 52/196 (26%), Positives = 72/196 (36%), Gaps = 34/196 (17%)

Query: 314  IQTLKTQHEEFVTSLAQQQQQQQQQQ--QQLQMPQMEAEVKATPPPPAPP--PAPAPAPA 369
            I  ++ +   FV S A  Q Q QQ +  + L+  +   + +  P     P  PA    PA
Sbjct: 883  ISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPADVEEPA 942

Query: 370  IPPTTQ-------PDDSKPPIQMPGSSEYEAPGGVQDPAAAGPR------GPGPHDQI-- 414
            +P T +       P D+KP ++   +    + GG     ++  R      G G  D    
Sbjct: 943  VPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFH 1002

Query: 415  PPNKPPWFDQPHPVAPW----------GQQQPPEQPPYPH-HQGGPPHCPPWNNSHEG-- 461
            P  +P    QP  V P           G QQPP  P  PH H   PP        H    
Sbjct: 1003 PEGQPQRLPQPPEVGPQPARKVTLTRGGLQQPPHLPAGPHAHSPVPPGIKSIQGIHPAKK 1062

Query: 462  --MWGEQRGDPGWNGQ 475
              M G  RG  G  G+
Sbjct: 1063 AIMHGRGRGVAGPMGR 1078



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 26/95 (27%), Positives = 30/95 (31%), Gaps = 19/95 (20%)

Query: 330 QQQQQQQQQQQQLQMPQMEAEVKATPPPPAPPPAPAPAPAIPPTTQPDDS---------- 379
           Q QQ QQQ   Q Q P          PP  PPP   P P  PP   P             
Sbjct: 593 QPQQPQQQPPPQHQPPHQ--------PPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSV 644

Query: 380 -KPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQ 413
             PP+      ++        P A+  R   P  Q
Sbjct: 645 PPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQ 679



 Score = 30.4 bits (67), Expect = 7.9
 Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 8/81 (9%)

Query: 310 FQQQIQTLKTQHEEFVTS--LAQQQQQQQQQQQQLQMPQMEAEVKATPPPPAPPPAPAPA 367
           ++ +I+  K   EE +    L +QQQ   ++++ L+    + +    PPPPA     A +
Sbjct: 790 YRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALS 849

Query: 368 PAIPPTTQPDDSKPPIQMPGS 388
           P+      P +  P +  PG+
Sbjct: 850 PS------PTNGNPLLPFPGA 864


>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
          Length = 320

 Score = 87.4 bits (215), Expect = 5e-17
 Identities = 61/122 (50%), Positives = 74/122 (60%), Gaps = 10/122 (8%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSR---SRSCSR 774
           R+K R+   +    R+S PS SRSRS+SR RSSS S SRS  SS   SRSR   SRS SR
Sbjct: 203 RSKSRSSHSRSSS-RSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSR 261

Query: 775 SY---SRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSA 831
           S+   S  R RS S S SS  R+R +SRSRS S    ++RR+RSRS   P S  +G N+ 
Sbjct: 262 SHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRS---PESQVIGENTK 318

Query: 832 PP 833
            P
Sbjct: 319 QP 320



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 54/105 (51%), Positives = 62/105 (59%), Gaps = 14/105 (13%)

Query: 729 QEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSR 788
           +E  N   S  RSRSKSR  S SRS+SRSS  S S SRSRSRS      RS S S+SRSR
Sbjct: 190 EEDSNKKKSNRRSRSKSRS-SHSRSSSRSSSPSSSRSRSRSRS------RSSSSSQSRSR 242

Query: 789 SSRSRSRSQSRSR-SKSYSPGRRRRSRSRSPTPPSSAGLGSNSAP 832
           SS   SR +SRSR SKS S  R  R    S +P   +   S+S+P
Sbjct: 243 SS---SRERSRSRGSKSRSSSRSHRG---SSSPRKRSYSSSSSSP 281



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 44/86 (51%), Positives = 51/86 (59%), Gaps = 5/86 (5%)

Query: 750 SSRSNSRSSKSSGSYSRSRSRSC-SRSYSRSRSRSRSRSRS-SRSRSRSQSRSRSKSYSP 807
           +S     + K S   SRS+SRS  SRS SRS S S SRSRS SRSRS S S+SRS+S S 
Sbjct: 187 ASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSS- 245

Query: 808 GRRRRSRSRSPTPPSSAGLGSNSAPP 833
             R RSRSR     SS+     S+ P
Sbjct: 246 --RERSRSRGSKSRSSSRSHRGSSSP 269


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 86.7 bits (213), Expect = 9e-17
 Identities = 70/164 (42%), Positives = 88/164 (53%), Gaps = 33/164 (20%)

Query: 706 EGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRS----SSRSNSRSSKSS 761
           +G E NG       K+R    K   +R    SRSRS S+SR RS     SRS S SSKSS
Sbjct: 161 DGTEVNG------RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSS 214

Query: 762 GSYSRSRSRSCSRSYSRSRSR--SRSRSRSSRSRSRSQSRSRSKSYSPGRRR-------- 811
            S SRSRSRS SRS S+SRSR  SRSRS+  +SRS S+ +SRS+S+S G+ R        
Sbjct: 215 HSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAE 274

Query: 812 ----------RSRSRSPTPPSSAGLGSNSAPPIPDSRLGEENKG 845
                     + +SRSP+   S    S S     + R+ EE +G
Sbjct: 275 EKIQNNDNVGKPKSRSPSRHKSK---SKSRSRSQERRVEEEKRG 315



 Score = 73.6 bits (179), Expect = 8e-13
 Identities = 59/143 (41%), Positives = 76/143 (53%), Gaps = 17/143 (11%)

Query: 697 PSHDRPRN---SEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSR- 752
           PS ++ R+   S G  ++   +    K++     G+ K  S PSR +S+SKSR RS  R 
Sbjct: 250 PSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS-PSRHKSKSKSRSRSQERR 308

Query: 753 ---------SNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSR-SRSSRSRSRSQSRSRS 802
                    S  RS + S   SRSRSRS   S SRSRSRS+S+  R  R RSR +SRSRS
Sbjct: 309 VEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRS 368

Query: 803 KSYSPGRRRRSRSRSPTPPSSAG 825
           +S S  +  RSR R     S AG
Sbjct: 369 RSRS--KSERSRKRGSKRDSKAG 389



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 55/130 (42%), Positives = 75/130 (57%), Gaps = 11/130 (8%)

Query: 698 SHDRPRN-SEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSR 756
           S  R R+ SE   + G     +A    +++K    R+   S SRS SK R  + S S+ R
Sbjct: 366 SRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQR 425

Query: 757 S----SKSSGSYSRSRSRSCSRSYSR----SRSRSRSRSRSSRSRSRSQSRSRSKSYSPG 808
                S+++G+   +RSRS S S S+    S SRSRS+S +S++RSRS+SRSRS S SP 
Sbjct: 426 EGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKS-ASKTRSRSKSRSRSASRSPS 484

Query: 809 R-RRRSRSRS 817
           R R RS SRS
Sbjct: 485 RSRSRSHSRS 494



 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 77/268 (28%), Positives = 119/268 (44%), Gaps = 30/268 (11%)

Query: 633 HINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEA 692
           H    +  ++  V Y D+   L     KL+  E   ++ + IRL    P S R  +   +
Sbjct: 136 HKGRKNEGVIEFVSYSDMKRALE----KLDGTE---VNGRKIRLVEDKPGSRRRRSYSRS 188

Query: 693 FYSPPSHDRPRNS-EGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSR---GR 748
                S  R R+S +   ++G  +   +K R+R R G   R+   SRS+SRS+S+    R
Sbjct: 189 RSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSR 248

Query: 749 SSSRSNSRSSKSSGSYSRSRSR-----------SCSRSYSRSRSRSRSRSRS-SRSRSRS 796
           S S+  SRS   S   SRS+S+           +  +  SRS SR +S+S+S SRS+ R 
Sbjct: 249 SPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERR 308

Query: 797 QSRSRSKSYSPGRR-----RRSRSRSPTPPSSAGLGSNSAPPIPDSRLGEENKGHQMLVK 851
               +  S S GR      R+SRSRS +   S    S S     D R G +    +   +
Sbjct: 309 VEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS-RSRSRSKSKDKRKGRKRSREESRSR 367

Query: 852 MGWSGSGGLGAKEQGIQDPIKGGDVRDK 879
              S S    ++++G +   K G  + K
Sbjct: 368 -SRSRSKSERSRKRGSKRDSKAGSSKKK 394



 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 45/110 (40%), Positives = 61/110 (55%), Gaps = 8/110 (7%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRS------RS 771
           +++ R++ R+ +E++    SR RS+ KS  +S SRS S+    S S SRS+S      R 
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK 358

Query: 772 CSRSYSRSRSRSRSRSRSSRSR--SRSQSRSRSKSYSPGRRRRSRSRSPT 819
            SR  SRSRSRSRS+S  SR R   R      SK        RS+SRSP+
Sbjct: 359 RSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPS 408



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 43/138 (31%), Positives = 65/138 (47%), Gaps = 7/138 (5%)

Query: 701 RPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKS 760
           R   S    + G     R++ +++ ++   KR+   SRSRSRS+S+   S +  S+    
Sbjct: 328 RQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSK 387

Query: 761 SGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRS--- 817
           +GS  + +     RS SRS SRS S+ R       SQ   R +S + G  + +RSRS   
Sbjct: 388 AGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSN 447

Query: 818 ----PTPPSSAGLGSNSA 831
               P  PS +   S SA
Sbjct: 448 SKSKPNLPSESRSRSKSA 465



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 55/141 (39%), Positives = 70/141 (49%), Gaps = 36/141 (25%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYS-------RSRSR 770
           R+K + +R+  +  R    SRSRSRSKS  RS  R + R SK+  S         RS+SR
Sbjct: 347 RSKSKDKRKGRKRSREESRSRSRSRSKSE-RSRKRGSKRDSKAGSSKKKKKEDTDRSQSR 405

Query: 771 SCSRSYSRSRSRSRSRS---------------RSSRSRSRS----------QSRSRSKSY 805
           S SRS S+ R  ++S S               + +RSRSRS          +SRSRSKS 
Sbjct: 406 SPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSA 465

Query: 806 SPGRRR---RSRSRSPTPPSS 823
           S  R R   RSRS S +P  S
Sbjct: 466 SKTRSRSKSRSRSASRSPSRS 486


>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
          Length = 344

 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 65/148 (43%), Positives = 81/148 (54%), Gaps = 23/148 (15%)

Query: 700 DRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRS-S 758
           D+PR S     +G     R++ R+RRR     R S  SRSRS SKSR RS SRS  RS S
Sbjct: 181 DKPRTSHRRSYSGS----RSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRS 236

Query: 759 KSSGSYSRSRSRSC------SRSYSRSR-------SRSRSRSRSSRSRSRSQSRSRSKSY 805
           +S G  SRS+S+S       S S+SRSR       SRSRSRSRS +   +   +S+S+S 
Sbjct: 237 RSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRS- 295

Query: 806 SPGRRRRSRSRSPTPPSSAGLGSNSAPP 833
               R +SRS SP P   +   S S PP
Sbjct: 296 ----RSQSRSNSPLPVPPSKARSVSPPP 319



 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 58/132 (43%), Positives = 72/132 (54%), Gaps = 22/132 (16%)

Query: 729 QEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSR 788
           ++K  +   RS S S+SR RS  RS SRS +SS S SRS S+S SRS SRS+ RSRSRS+
Sbjct: 180 EDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSK 239

Query: 789 SSRSRSRSQ------------SRSRSKSYSPGRRRRSRSRSPTPPSSAGL---------- 826
             +SRS+S+            SRSRSK      R RSRSRSP       +          
Sbjct: 240 GRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQS 299

Query: 827 GSNSAPPIPDSR 838
            SNS  P+P S+
Sbjct: 300 RSNSPLPVPPSK 311



 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 49/120 (40%), Positives = 62/120 (51%), Gaps = 12/120 (10%)

Query: 722 RARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRS 781
           + R  +G  +  S     R+  K  G   +  N R  +     S  RS S SRS SRSR 
Sbjct: 143 KERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRR 202

Query: 782 RSRSRSR-----------SSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNS 830
           RSRSRSR            SRSRSRS+S+ RS+S S GR+ RS+S+S  P S  G  S+S
Sbjct: 203 RSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKS-KPKSDRGSHSHS 261



 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 50/122 (40%), Positives = 66/122 (54%), Gaps = 31/122 (25%)

Query: 718 RAKMRARRRKGQEKRNSG-PSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRS- 775
           R++ R+R +     R+ G  SRS+S+SK +    S S+SR S+S   Y +SRSRS SRS 
Sbjct: 223 RSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSR-SRSKDEYEKSRSRSRSRSP 281

Query: 776 --------YSRSRSRSRSRSRS--------------------SRSRSRSQSRSRSKSYSP 807
                    S+SRSRS+SRS S                    SRSRSRS+S+SRS+S S 
Sbjct: 282 KENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSS 341

Query: 808 GR 809
            R
Sbjct: 342 SR 343


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 59/118 (50%), Positives = 72/118 (61%), Gaps = 7/118 (5%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSR---SRSCSR 774
           R+K R+   +    R+S PS SRSRS+SR RSSS S SRS  SS   SRSR   SRS SR
Sbjct: 203 RSKSRSSHSRSSS-RSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSR 261

Query: 775 SY---SRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSN 829
           S+   S  R RS S S SS  R+R +SRSRS S    ++RR+RSRSP     +  GS+
Sbjct: 262 SHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSS 319



 Score = 80.9 bits (198), Expect = 5e-15
 Identities = 57/107 (53%), Positives = 65/107 (60%), Gaps = 10/107 (9%)

Query: 729 QEKRNSGPSRSRSRSKSRG---RSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRS 785
           +E  N   S  RSRSKSR    RSSSRS+S SS  S S SRSRS S S+S SRS SR RS
Sbjct: 190 EEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERS 249

Query: 786 RSRSSRSRSRSQS-------RSRSKSYSPGRRRRSRSRSPTPPSSAG 825
           RSR S+SRS S+S       R RS S S     R+R RS +  SS+G
Sbjct: 250 RSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSG 296



 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 50/104 (48%), Positives = 57/104 (54%), Gaps = 5/104 (4%)

Query: 731 KRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSS 790
           K N   S     +K +    SRS SRSS S  S   SRS S S S SRSRSRSRS S SS
Sbjct: 182 KYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSS---SRSSSPSSSRSRSRSRSRS-SSSS 237

Query: 791 RSRSRSQSRSRSKSYSPGRRRRSRS-RSPTPPSSAGLGSNSAPP 833
           +SRSRS SR RS+S     R  SRS R  + P      S+S+ P
Sbjct: 238 QSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSP 281



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 50/126 (39%), Positives = 63/126 (50%), Gaps = 21/126 (16%)

Query: 698 SHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRS 757
           S  R  +S    ++      R++ R+R R     ++   S SR RS+SRG S SRS+SRS
Sbjct: 204 SKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRG-SKSRSSSRS 262

Query: 758 ------------SKSSGSYSRSRSRSCSRSYS---RSRSRSRSRS-----RSSRSRSRSQ 797
                       S SS S  R+R RS SRS S   R + R+RSRS     RSS   S S 
Sbjct: 263 HRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSG 322

Query: 798 SRSRSK 803
           SRS SK
Sbjct: 323 SRSSSK 328


>gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
          Length = 1337

 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 88/314 (28%), Positives = 114/314 (36%), Gaps = 41/314 (13%)

Query: 513 PFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFD 572
           PF    PP  +GP PP    P F      H F   PP F     PP  P    P      
Sbjct: 80  PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFP-VPPCF--PPMPPPMPCPNNPPVPGAP 136

Query: 573 YPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPP 632
             QG FP  M PP       MPHP     PP   PQ  ++  PP             G  
Sbjct: 137 PGQGTFPFMMPPPS------MPHPP----PPPVMPQQVNYQYPP-------------GYS 173

Query: 633 HINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEA 692
           H N   PS      + + P+  +          ++ L P     P P  PSER       
Sbjct: 174 HHNFPPPSFNS---FQNNPSSFLPSANNSSSPHFRHLPP----YPLPKAPSERRSPERLK 226

Query: 693 FYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNS-----GPSRSRSRSKSRG 747
            Y    H    +  G     L    R +   RRR+    R+       PSR RS  +SR 
Sbjct: 227 HYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRE 286

Query: 748 RSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSR---SQSRSRSKS 804
           R   R   R ++ S S  RS  +   RS SRS SR + R+R    + R   +QS  + K+
Sbjct: 287 RERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKN 346

Query: 805 YSPGRRRRSRSRSP 818
           Y+  + +      P
Sbjct: 347 YTSIKEKEPEETMP 360



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 71/292 (24%), Positives = 91/292 (31%), Gaps = 63/292 (21%)

Query: 357 PPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPP 416
           P  PP      P   P+T   +S  P  +P   ++        P+A GP  P P    PP
Sbjct: 44  PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIR--PP 101

Query: 417 NKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGP-PHCPPWNNSHEGMWGEQRGDPGWNGQ 475
                   P PV P     PP  PP P     P P  PP                   GQ
Sbjct: 102 FPNHQMRHPFPVPPC---FPPMPPPMPCPNNPPVPGAPP-------------------GQ 139

Query: 476 RDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQF 535
              P            F  P  S    PP       PP     P      +PP   H  F
Sbjct: 140 GTFP------------FMMPPPSMPHPPP-------PPV---MPQQVNYQYPPGYSHHNF 177

Query: 536 NQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPH---HHPGHR 592
             PP  ++F   P  F+    P  +    P + H   YP    P+E   P    H+  HR
Sbjct: 178 -PPPSFNSFQNNPSSFL----PSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHR 232

Query: 593 MPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPN 644
                  +H    G +H           G+ P  RRQ   + +  D    P+
Sbjct: 233 H-----RDHSHGRGERHRSL---DRRERGRSPDRRRQDSRYRSDYDRGRTPS 276



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 36/111 (32%), Positives = 41/111 (36%), Gaps = 12/111 (10%)

Query: 356 PPPAPPPAPAPAPAIP-----PTTQPDD--SKPPIQMPGSSEYEAPGGVQDPAAAGPRGP 408
           PPP PP A  P P  P     P  Q       PP   P       P     P A   +G 
Sbjct: 82  PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGT 141

Query: 409 GPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPP-YPHHQGGPPHCPPWNNS 458
            P    PP+ P     P PV P  QQ   + PP Y HH   PP    + N+
Sbjct: 142 FPFMMPPPSMP--HPPPPPVMP--QQVNYQYPPGYSHHNFPPPSFNSFQNN 188



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 28/98 (28%), Positives = 32/98 (32%), Gaps = 9/98 (9%)

Query: 355 PP--PPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAG---PRGPG 409
           PP  PP PPP P P     P   P     P  MP  S    P     P       P G  
Sbjct: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYS 173

Query: 410 PHDQIPPNKPPWFDQPHPVAPWGQQQPPEQ----PPYP 443
            H+  PP+   + + P    P             PPYP
Sbjct: 174 HHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYP 211


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 142/578 (24%), Positives = 197/578 (34%), Gaps = 80/578 (13%)

Query: 320 QHEEFVTSLAQQQQQQQQQQQQLQMPQMEAEVKATPPPPAPP-PAPAPAP---AIPPTTQ 375
           Q  E  +  + QQQ  Q Q   LQ P       ++ PP  P  P P P P   A+PP   
Sbjct: 165 QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS 224

Query: 376 PDDSKPPIQ-------MPGSSEYEAPG--GVQDPAAAGPRGPGPHDQIPPNKPPWFDQPH 426
           P  S+ P Q       +P +   +AP     + P+   P  P PH   PP +P       
Sbjct: 225 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH---PPLQPLTGSAGQ 281

Query: 427 PVAPWGQQQPP---EQPPYPHH-QGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNN 482
           P AP    QPP   + PP PH  Q GP    P      G+       P    Q  AP   
Sbjct: 282 PSAP-SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL-------PPQASQGQAPLGT 333

Query: 483 QPDAAW-NSQFEGPWNS---QHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQP 538
            P AA+ ++  + P +    Q +QPP    Q  PP  +  P     P  P  Q P     
Sbjct: 334 SPAAAYPHTSLQLPASQSALQSQQPP--REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAH 391

Query: 539 PHPHNFNRFPPRFMQDDFPP------------RHPFERPPYPHRF---DYPQGDFPAEMG 583
            HP + +   P  M  + PP             HP    P P +      P    PA+  
Sbjct: 392 KHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ-- 449

Query: 584 PPHHHPGHRMP-----HPGINEH-----PPWAGPQHP--DFGPPPHGFNGQPPHMRRQGP 631
           PP       +P     HP    H     PP+A  QHP    GPPP      P        
Sbjct: 450 PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFA--QHPFVPGGPPPITPPTCPSTSTPPAG 507

Query: 632 PHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVE 691
           P  +   P          +  G   PL  ++  E    D ++   PPP P S    +   
Sbjct: 508 PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSP---SPEP 564

Query: 692 AFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSS 751
                PSH           +    F++   R      +      P      +K R  +  
Sbjct: 565 TVVDTPSH----------ASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIE 614

Query: 752 RSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRR 811
           ++  R ++      R R +   +   R R R R   R++++ S +     S     G   
Sbjct: 615 KA-KREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGH 673

Query: 812 RSRSRSPTPPSSAGLGSNSAPPIPDSR-LGEENKGHQM 848
              S  P P + A +     P  P  R L E  + H M
Sbjct: 674 MRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVM 711



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 33/128 (25%), Positives = 53/128 (41%), Gaps = 24/128 (18%)

Query: 721 MRARR--------RKGQEKRNSGPS----------RSRSRSKSRGRSSSRSNSRSSKSSG 762
           MR RR        R G++K+ + P           RS  R+     S+S ++S++     
Sbjct: 18  MRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKK 77

Query: 763 SYSRSRSRSCSRSYSRSRSRSRSRS------RSSRSRSRSQSRSRSKSYSPGRRRRSRSR 816
           S  + +  + S   S  R R +  S      R+S  ++++Q  SR  S S G    S SR
Sbjct: 78  SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSR 137

Query: 817 SPTPPSSA 824
           S     S+
Sbjct: 138 SVNDEGSS 145



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 30/99 (30%), Positives = 35/99 (35%), Gaps = 21/99 (21%)

Query: 527 PPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERP----PYPHRFDYPQGDFPAEM 582
           P H QH   +   H H  +       Q    P HP   P    P+  RF YP G  P  +
Sbjct: 870 PHHHQHSHIHSHLHLHQQDPLH----QGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPL 925

Query: 583 --GPPHHHPGHRMPHPGINEHPPWAGPQHPDFG---PPP 616
              PPH H   R        HP +  P   D     PPP
Sbjct: 926 LGQPPHEHEMLR--------HPVFGTPYPRDLPGAIPPP 956



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 52/210 (24%), Positives = 70/210 (33%), Gaps = 36/210 (17%)

Query: 510 REPPFRMQRPPHFRGPFPPHQQ--HPQFNQPPH--PHNFNRFPPRFMQDDFPPRHPFERP 565
           RE   R +  P F    PP     HP  N   H   H+    PP      F   HP   P
Sbjct: 761 RERELRERMKPGFEVK-PPELDPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNP 819

Query: 566 PYPHRFDY------PQGDFPAEMGPPHHH----------PGHRMPHPGINEHPPWAGPQH 609
               R         P+  +P  +     H          P  R+    +  H      QH
Sbjct: 820 LERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHH----QH 875

Query: 610 PDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAG-LMAPLVKLEDHEYKP 668
                  H     P H    GP H   D  +  P++  F  P G L  PL+    HE++ 
Sbjct: 876 SHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEM 935

Query: 669 LD--------PKDI--RLPPPMPPSERLLA 688
           L         P+D+   +PPPM  + +L A
Sbjct: 936 LRHPVFGTPYPRDLPGAIPPPMSAAHQLQA 965


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 142/578 (24%), Positives = 197/578 (34%), Gaps = 80/578 (13%)

Query: 320  QHEEFVTSLAQQQQQQQQQQQQLQMPQMEAEVKATPPPPAPP-PAPAPAP---AIPPTTQ 375
            Q  E  +  + QQQ  Q Q   LQ P       ++ PP  P  P P P P   A+PP   
Sbjct: 719  QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS 778

Query: 376  PDDSKPPIQ-------MPGSSEYEAPG--GVQDPAAAGPRGPGPHDQIPPNKPPWFDQPH 426
            P  S+ P Q       +P +   +AP     + P+   P  P PH   PP +P       
Sbjct: 779  PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH---PPLQPLTGSAGQ 835

Query: 427  PVAPWGQQQPP---EQPPYPHH-QGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNN 482
            P AP    QPP   + PP PH  Q GP    P      G+       P    Q  AP   
Sbjct: 836  PSAP-SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL-------PPQASQGQAPLGT 887

Query: 483  QPDAAW-NSQFEGPWNS---QHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQP 538
             P AA+ ++  + P +    Q +QPP    Q  PP  +  P     P  P  Q P     
Sbjct: 888  SPAAAYPHTSLQLPASQSALQSQQPP--REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAH 945

Query: 539  PHPHNFNRFPPRFMQDDFPP------------RHPFERPPYPHRF---DYPQGDFPAEMG 583
             HP + +   P  M  + PP             HP    P P +      P    PA+  
Sbjct: 946  KHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ-- 1003

Query: 584  PPHHHPGHRMP-----HPGINEH-----PPWAGPQHP--DFGPPPHGFNGQPPHMRRQGP 631
            PP       +P     HP    H     PP+A  QHP    GPPP      P        
Sbjct: 1004 PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFA--QHPFVPGGPPPITPPTCPSTSTPPAG 1061

Query: 632  PHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVE 691
            P  +   P          +  G   PL  ++  E    D ++   PPP P S    +   
Sbjct: 1062 PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSP---SPEP 1118

Query: 692  AFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSS 751
                 PSH           +    F++   R      +      P      +K R  +  
Sbjct: 1119 TVVDTPSH----------ASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIE 1168

Query: 752  RSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRR 811
            ++  R ++      R R +   +   R R R R   R++++ S +     S     G   
Sbjct: 1169 KA-KREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGH 1227

Query: 812  RSRSRSPTPPSSAGLGSNSAPPIPDSR-LGEENKGHQM 848
               S  P P + A +     P  P  R L E  + H M
Sbjct: 1228 MRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVM 1265



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 33/128 (25%), Positives = 53/128 (41%), Gaps = 24/128 (18%)

Query: 721 MRARR--------RKGQEKRNSGPS----------RSRSRSKSRGRSSSRSNSRSSKSSG 762
           MR RR        R G++K+ + P           RS  R+     S+S ++S++     
Sbjct: 572 MRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKK 631

Query: 763 SYSRSRSRSCSRSYSRSRSRSRSRS------RSSRSRSRSQSRSRSKSYSPGRRRRSRSR 816
           S  + +  + S   S  R R +  S      R+S  ++++Q  SR  S S G    S SR
Sbjct: 632 SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSR 691

Query: 817 SPTPPSSA 824
           S     S+
Sbjct: 692 SVNDEGSS 699



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 30/99 (30%), Positives = 35/99 (35%), Gaps = 21/99 (21%)

Query: 527  PPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERP----PYPHRFDYPQGDFPAEM 582
            P H QH   +   H H  +       Q    P HP   P    P+  RF YP G  P  +
Sbjct: 1424 PHHHQHSHIHSHLHLHQQDPLH----QGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPL 1479

Query: 583  --GPPHHHPGHRMPHPGINEHPPWAGPQHPDFG---PPP 616
               PPH H   R        HP +  P   D     PPP
Sbjct: 1480 LGQPPHEHEMLR--------HPVFGTPYPRDLPGAIPPP 1510



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 52/210 (24%), Positives = 70/210 (33%), Gaps = 36/210 (17%)

Query: 510  REPPFRMQRPPHFRGPFPPHQQ--HPQFNQPPH--PHNFNRFPPRFMQDDFPPRHPFERP 565
            RE   R +  P F    PP     HP  N   H   H+    PP      F   HP   P
Sbjct: 1315 RERELRERMKPGFEVK-PPELDPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNP 1373

Query: 566  PYPHRFDY------PQGDFPAEMGPPHHH----------PGHRMPHPGINEHPPWAGPQH 609
                R         P+  +P  +     H          P  R+    +  H      QH
Sbjct: 1374 LERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHH----QH 1429

Query: 610  PDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAG-LMAPLVKLEDHEYKP 668
                   H     P H    GP H   D  +  P++  F  P G L  PL+    HE++ 
Sbjct: 1430 SHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEM 1489

Query: 669  LD--------PKDI--RLPPPMPPSERLLA 688
            L         P+D+   +PPPM  + +L A
Sbjct: 1490 LRHPVFGTPYPRDLPGAIPPPMSAAHQLQA 1519


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 142/578 (24%), Positives = 197/578 (34%), Gaps = 80/578 (13%)

Query: 320  QHEEFVTSLAQQQQQQQQQQQQLQMPQMEAEVKATPPPPAPP-PAPAPAP---AIPPTTQ 375
            Q  E  +  + QQQ  Q Q   LQ P       ++ PP  P  P P P P   A+PP   
Sbjct: 719  QDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGS 778

Query: 376  PDDSKPPIQ-------MPGSSEYEAPG--GVQDPAAAGPRGPGPHDQIPPNKPPWFDQPH 426
            P  S+ P Q       +P +   +AP     + P+   P  P PH   PP +P       
Sbjct: 779  PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH---PPLQPLTGSAGQ 835

Query: 427  PVAPWGQQQPP---EQPPYPHH-QGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNN 482
            P AP    QPP   + PP PH  Q GP    P      G+       P    Q  AP   
Sbjct: 836  PSAP-SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL-------PPQASQGQAPLGT 887

Query: 483  QPDAAW-NSQFEGPWNS---QHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQP 538
             P AA+ ++  + P +    Q +QPP    Q  PP  +  P     P  P  Q P     
Sbjct: 888  SPAAAYPHTSLQLPASQSALQSQQPP--REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAH 945

Query: 539  PHPHNFNRFPPRFMQDDFPP------------RHPFERPPYPHRF---DYPQGDFPAEMG 583
             HP + +   P  M  + PP             HP    P P +      P    PA+  
Sbjct: 946  KHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ-- 1003

Query: 584  PPHHHPGHRMP-----HPGINEH-----PPWAGPQHP--DFGPPPHGFNGQPPHMRRQGP 631
            PP       +P     HP    H     PP+A  QHP    GPPP      P        
Sbjct: 1004 PPGLTQSQNLPPPPASHPPTGLHQVAPQPPFA--QHPFVPGGPPPITPPTCPSTSTPPAG 1061

Query: 632  PHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVE 691
            P  +   P          +  G   PL  ++  E    D ++   PPP P S    +   
Sbjct: 1062 PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSP---SPEP 1118

Query: 692  AFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSS 751
                 PSH           +    F++   R      +      P      +K R  +  
Sbjct: 1119 TVVDTPSH----------ASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIE 1168

Query: 752  RSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRR 811
            ++  R ++      R R +   +   R R R R   R++++ S +     S     G   
Sbjct: 1169 KA-KREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGH 1227

Query: 812  RSRSRSPTPPSSAGLGSNSAPPIPDSR-LGEENKGHQM 848
               S  P P + A +     P  P  R L E  + H M
Sbjct: 1228 MRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVM 1265



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 33/128 (25%), Positives = 53/128 (41%), Gaps = 24/128 (18%)

Query: 721 MRARR--------RKGQEKRNSGPS----------RSRSRSKSRGRSSSRSNSRSSKSSG 762
           MR RR        R G++K+ + P           RS  R+     S+S ++S++     
Sbjct: 572 MRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKK 631

Query: 763 SYSRSRSRSCSRSYSRSRSRSRSRS------RSSRSRSRSQSRSRSKSYSPGRRRRSRSR 816
           S  + +  + S   S  R R +  S      R+S  ++++Q  SR  S S G    S SR
Sbjct: 632 SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSR 691

Query: 817 SPTPPSSA 824
           S     S+
Sbjct: 692 SVNDEGSS 699



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 30/99 (30%), Positives = 35/99 (35%), Gaps = 21/99 (21%)

Query: 527  PPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERP----PYPHRFDYPQGDFPAEM 582
            P H QH   +   H H  +       Q    P HP   P    P+  RF YP G  P  +
Sbjct: 1424 PHHHQHSHIHSHLHLHQQDPLH----QGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPL 1479

Query: 583  --GPPHHHPGHRMPHPGINEHPPWAGPQHPDFG---PPP 616
               PPH H   R        HP +  P   D     PPP
Sbjct: 1480 LGQPPHEHEMLR--------HPVFGTPYPRDLPGAIPPP 1510



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 52/210 (24%), Positives = 70/210 (33%), Gaps = 36/210 (17%)

Query: 510  REPPFRMQRPPHFRGPFPPHQQ--HPQFNQPPH--PHNFNRFPPRFMQDDFPPRHPFERP 565
            RE   R +  P F    PP     HP  N   H   H+    PP      F   HP   P
Sbjct: 1315 RERELRERMKPGFEVK-PPELDPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNP 1373

Query: 566  PYPHRFDY------PQGDFPAEMGPPHHH----------PGHRMPHPGINEHPPWAGPQH 609
                R         P+  +P  +     H          P  R+    +  H      QH
Sbjct: 1374 LERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHH----QH 1429

Query: 610  PDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAG-LMAPLVKLEDHEYKP 668
                   H     P H    GP H   D  +  P++  F  P G L  PL+    HE++ 
Sbjct: 1430 SHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEM 1489

Query: 669  LD--------PKDI--RLPPPMPPSERLLA 688
            L         P+D+   +PPPM  + +L A
Sbjct: 1490 LRHPVFGTPYPRDLPGAIPPPMSAAHQLQA 1519


>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
          Length = 221

 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 57/102 (55%), Positives = 68/102 (66%), Gaps = 9/102 (8%)

Query: 728 GQEKRNSGPSRSR-SRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSR 786
           G  +R+  P R R SRS+SR RS SRS SR S+S    SRSR+RS SRS S+SRS  RS+
Sbjct: 114 GYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSK---SRSRTRSRSRSTSKSRSARRSK 170

Query: 787 SRSS-----RSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSS 823
           S+SS     RSRSRS+SRSRS      R  +SRSRS +PP S
Sbjct: 171 SKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKS 212



 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 53/115 (46%), Positives = 67/115 (58%), Gaps = 3/115 (2%)

Query: 696 PPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSK---SRGRSSSR 752
           PP     R      + G   + R     RRR+    R+   SRSRSRS+   S+ RS +R
Sbjct: 95  PPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTR 154

Query: 753 SNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSP 807
           S SRS+  S S  RS+S+S S S SRSRSRSRSRSRS    S+ +S+SRS+S SP
Sbjct: 155 SRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSP 209



 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 58/111 (52%), Positives = 66/111 (59%), Gaps = 11/111 (9%)

Query: 732 RNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSR 791
           R S   R R RS+SR RS SRS SRS      YSRS+SRS +RS SRS S+SRS +R S+
Sbjct: 117 RRSRSPRRRRRSRSRSRSRSRSRSRSR-----YSRSKSRSRTRSRSRSTSKSRS-ARRSK 170

Query: 792 SRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLGEE 842
           S+S S SRSRS+S     R RSRSRSP P S     S S    P     EE
Sbjct: 171 SKSSSVSRSRSRS-----RSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEE 216



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 27/53 (50%), Positives = 30/53 (56%)

Query: 767 SRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPT 819
           SR     R Y       RSRS   R RSRS+SRSRS+S S  R  RS+SRS T
Sbjct: 101 SRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRT 153


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 84.7 bits (208), Expect = 4e-16
 Identities = 97/339 (28%), Positives = 115/339 (33%), Gaps = 59/339 (17%)

Query: 345 PQMEAEVKATPPPPAPPPAPAP----APAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDP 400
           PQ   + +  PPPP  P  P P     P  PP        PP      S    PG  Q P
Sbjct: 62  PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 121

Query: 401 AAAG---PRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNN 457
              G   P+GP P    PP KP    Q  P  P G  +P   PP    QG PP     + 
Sbjct: 122 PPQGGNQPQGPPP----PPGKP----QGPP--PQGGNKPQGPPPPGKPQGPPPQGDNKSR 171

Query: 458 SHEGMWGEQRGDPGWNGQR--------DAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQ 509
           S     G+ +G P   G +          P    P      Q   P       PP G  +
Sbjct: 172 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK 231

Query: 510 ----REPPFRMQRPP-----HFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRH 560
               R PP + Q PP       +GP PP    PQ   PP   N  + PP       PP  
Sbjct: 232 SQSARSPPGKPQGPPPQGGNQPQGP-PPPPGKPQ-GPPPQGGNKPQGPP-------PPGK 282

Query: 561 PFERPPYPHRFDYPQGDFPAE-MGPP---HHHPGHRMPHPGINEHPPWAGPQHPDFGPPP 616
           P   PP            P +  GPP    + P    P PG  + PP  G   P   PPP
Sbjct: 283 PQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 342

Query: 617 HGFNGQPPH------------MRRQGPPHINHDDPSLVP 643
               G PP              + QGPP    ++P   P
Sbjct: 343 GKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPP 381



 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 96/317 (30%), Positives = 113/317 (35%), Gaps = 65/317 (20%)

Query: 345 PQMEAEVKATPPPPAPPPAPAPAPAIPPTTQPDDSKPPIQMP-----GSSEYEAPGGVQD 399
           PQ   + +  PPPP  P  P P     P   P   KP    P       S    PG  Q 
Sbjct: 123 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG 182

Query: 400 PAAAG---PRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWN 456
           P   G   P+GP P    PP KP    Q  P  P G  +P   PP    QG PP     +
Sbjct: 183 PPPQGGNQPQGPPP----PPGKP----QGPP--PQGGNKPQGPPPPGKPQGPPPQGDNKS 232

Query: 457 NSHEGMWGEQRGDPGWNGQRDA--------PWNNQPDAAWNSQFEGPWNSQHEQPPWGGG 508
            S     G+ +G P   G +          P    P      Q   P       PP GG 
Sbjct: 233 QSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS 292

Query: 509 Q----REPPFRMQRPP-----HFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPR 559
           +    R PP + Q PP       +GP PP    PQ   PP   N  + PP       PP 
Sbjct: 293 KSRSSRSPPGKPQGPPPQGGNQPQGP-PPPPGKPQ-GPPPQGGNKPQGPP-------PPG 343

Query: 560 HPFERPPYPHRFDYPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGF 619
            P + PP       PQG   +           R P PG  + PP     +P   PPP G 
Sbjct: 344 KP-QGPP-------PQGGSKSRSA--------RSP-PGKPQGPPQQEGNNPQGPPPPAGG 386

Query: 620 NGQ----PPHMRRQGPP 632
           N Q    PP  + QGPP
Sbjct: 387 NPQQPQAPPAGQPQGPP 403



 Score = 80.1 bits (196), Expect = 9e-15
 Identities = 88/313 (28%), Positives = 109/313 (34%), Gaps = 27/313 (8%)

Query: 345 PQMEAEVKATPPPPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAG 404
           PQ   + +  P PP  P  P P        QP    PP   P     +     Q P   G
Sbjct: 41  PQGGNKPQGPPSPPGKPQGPPPQGG----NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 96

Query: 405 -PRGPGPH--DQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEG 461
            P+GP P       P  PP   +P    P G  QP   PP P    GPP  P   N  +G
Sbjct: 97  KPQGPPPQGDKSRSPRSPP--GKPQGPPPQGGNQPQGPPPPPGKPQGPP--PQGGNKPQG 152

Query: 462 --MWGEQRGDPGWNGQRDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRP 519
               G+ +G P     +     + P        +G    Q   PP G  Q  PP    +P
Sbjct: 153 PPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 212

Query: 520 PHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFP-----PRHPFERPPYPHRFDYP 574
              +GP PP +      Q  +     R PP   Q   P     P+ P   PP   +   P
Sbjct: 213 ---QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP-PPPPGKPQGPPP 268

Query: 575 QGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFN----GQPPHMRRQG 630
           QG    +  PP   P    P  G       + P  P  GPPP G N      PP  + QG
Sbjct: 269 QGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQ-GPPPQGGNQPQGPPPPPGKPQG 327

Query: 631 PPHINHDDPSLVP 643
           PP    + P   P
Sbjct: 328 PPPQGGNKPQGPP 340



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 79/268 (29%), Positives = 102/268 (38%), Gaps = 26/268 (9%)

Query: 389 SEYEAPGGVQ-DPAAAGPRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQG 447
           S+ E+P  +  +P  A P+G G   Q PP+ P    +P    P G  QP   PP P    
Sbjct: 24  SQEESPSLIAGNPQGAPPQG-GNKPQGPPSPP---GKPQGPPPQGGNQPQGPPPPPGKPQ 79

Query: 448 GPPHCPPWNNSHEG--MWGEQRGDPGWNGQRDAPWNNQPDAAWNSQFEGPWNSQHEQPPW 505
           GPP  P   N  +G    G+ +G P    +  +P  + P        +G    Q   PP 
Sbjct: 80  GPP--PQGGNKPQGPPPPGKPQGPPPQGDKSRSP-RSPPGKPQGPPPQGGNQPQGPPPPP 136

Query: 506 GGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPP--RHPFE 563
           G  Q  PP    +P   +GP PP +      Q  +    +R PP   Q   P     P  
Sbjct: 137 GKPQGPPPQGGNKP---QGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQG 193

Query: 564 RPPYPHRFDYPQGDFP----AEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGF 619
            PP P +   PQG  P       GPP        P  G N+      P     GPPP G 
Sbjct: 194 PPPPPGK---PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGG 250

Query: 620 N----GQPPHMRRQGPPHINHDDPSLVP 643
           N      PP  + QGPP    + P   P
Sbjct: 251 NQPQGPPPPPGKPQGPPPQGGNKPQGPP 278



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 40/133 (30%), Positives = 49/133 (36%), Gaps = 28/133 (21%)

Query: 345 PQMEAEVKATPPPPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAG 404
           PQ  ++ +++  PP  P  P P        QP    PP   P     +     Q P   G
Sbjct: 288 PQGGSKSRSSRSPPGKPQGPPPQGG----NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 343

Query: 405 -PRGPGPHD-------QIPPNKPPWFDQ--------PHPVAPWGQQQP-------PEQPP 441
            P+GP P         + PP KP    Q        P P A    QQP       P+ PP
Sbjct: 344 KPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP 403

Query: 442 YPHHQGGPPHCPP 454
            P  QGG P  PP
Sbjct: 404 RP-PQGGRPSRPP 415


>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
           [Homo sapiens]
          Length = 1125

 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 101/336 (30%), Positives = 117/336 (34%), Gaps = 63/336 (18%)

Query: 349 AEVKATPP-PPAPPPAPAPAPAIP---PTTQPDDSKPPIQMPGSSEYEA--PGGVQDPAA 402
           AE   T P  P P P P P P IP   P T P    PP Q PG     A  P     P  
Sbjct: 647 AETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQ-PGPPVVGALQPPAFTPPLG 705

Query: 403 AGPRGPGPHDQIPPNKPPWFD---QPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWN--N 457
             P G GP    PP  PP+      P  + P      P  P  P     PPH PP +  N
Sbjct: 706 IPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPN 765

Query: 458 SHEGMWGE-QRGD----------PGWNGQRDAPWNNQPDAAWNSQFEGPWNSQHEQPPWG 506
              G  G  + GD          P        P   QP +   +Q   P      Q P  
Sbjct: 766 LVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPST 825

Query: 507 G--GQREPPFRMQR-----PPHFR-------GPFPPHQQHPQFNQPPHPHNFNRFPPRFM 552
           G  G R     +QR     PPH +        P PPH  H     PP P  F   PP  M
Sbjct: 826 GLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHR--GPPPGPGGFAMPPPHGM 883

Query: 553 QDDFPPRHPFERPPYPHRFDYPQGDFPAEMGP------PHHHPGHRMPHPGINEHPPWAG 606
           +  FPP  PF RP          G  P   GP      P    G + P     + P    
Sbjct: 884 KGPFPPHGPFVRP----------GGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQA 933

Query: 607 PQHP----DFGPPPHGFNGQPPHMRRQGPPHINHDD 638
           PQ P       PPP   + QPP  ++Q P    +D+
Sbjct: 934 PQQPQQQQQQQPPP---SQQPPPTQQQ-PQQFRNDN 965



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 92/352 (26%), Positives = 116/352 (32%), Gaps = 93/352 (26%)

Query: 249 FLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQ---YQATLINEYSSVVQP 305
           +L   EDK  KI R+L LW+KNG F   IIQ L   A G          + N   S   P
Sbjct: 100 YLCPSEDKS-KIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEGSPPPP 158

Query: 306 VQLAFQQQIQTLKTQ----------------HEEFVTSLAQQQQQQQQQQQQLQMPQ--- 346
           V+++ +   Q                      + F T+  QQ QQ  Q  QQ   PQ   
Sbjct: 159 VKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKPQSPA 218

Query: 347 -----------MEAEVKATPPPPAPPPAPAPAPAIPPTTQPD--DSKPPIQMPGSSEYEA 393
                      + A++K TP  P+   A     A PP  Q    D K   +     E EA
Sbjct: 219 LDNAVMAQVQAITAQLKTTPTQPSEQKA-----AFPPPEQKTAFDKKLLDRFDYDDEPEA 273

Query: 394 PGGVQDPAAAGPRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCP 453
               +           P   +PP   P    P   AP     PP Q P+           
Sbjct: 274 VEESKKEDTTAVTTTAPAAAVPP--APTATVPAAAAPAAASPPPPQAPF----------- 320

Query: 454 PWNNSHEGMWGEQRGDPGWNGQRDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPP 513
                         G PG   Q+ A   +Q             N    QP   G Q    
Sbjct: 321 --------------GFPGDGMQQPAYTQHQ-------------NMDQFQPRMMGIQ---- 349

Query: 514 FRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERP 565
              Q P H + P PP+ Q P F   P P     FPP   Q   PP  P ++P
Sbjct: 350 ---QDPMHHQVPLPPNGQMPGFGLLPTP----PFPP-MAQPVIPPTPPVQQP 393



 Score = 60.5 bits (145), Expect = 7e-09
 Identities = 79/308 (25%), Positives = 107/308 (34%), Gaps = 69/308 (22%)

Query: 518 RPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFER------------- 564
           +P   +  FPP +Q   F++        +   RF  DD P      +             
Sbjct: 240 QPSEQKAAFPPPEQKTAFDK--------KLLDRFDYDDEPEAVEESKKEDTTAVTTTAPA 291

Query: 565 ---PPYPHRFDYPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPD-FGPPPHGFN 620
              PP P     P    PA   PP        P  G+ + P +   Q+ D F P   G  
Sbjct: 292 AAVPPAPTA-TVPAAAAPAAASPPPPQAPFGFPGDGMQQ-PAYTQHQNMDQFQPRMMGIQ 349

Query: 621 GQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPM 680
             P H +   PP+       L+P  P+      +  P++                  PP 
Sbjct: 350 QDPMHHQVPLPPNGQMPGFGLLPTPPF----PPMAQPVI------------------PPT 387

Query: 681 PPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQE-KRNSGPSRS 739
           PP ++   A     + P   +P   E              M   +   QE KR+   +R 
Sbjct: 388 PPVQQPFQASFQAQNEPLTQKPHQQE--------------MEVEQPCIQEVKRHMSDNR- 432

Query: 740 RSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSR 799
               KSR RS+SRS  R    SGS SR      SRS SR R R   RSRS   R R + R
Sbjct: 433 ----KSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKER 488

Query: 800 SRSKSYSP 807
            R +   P
Sbjct: 489 ERRQKGLP 496



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 76/269 (28%), Positives = 100/269 (37%), Gaps = 63/269 (23%)

Query: 355 PPPPAPPPAPAPAPAIPPTTQPD------------DS-----------------KPPIQM 385
           PPPP  PP   P P  PP + P+            DS                  PP+  
Sbjct: 743 PPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQ 802

Query: 386 PGS---SEYEAPG---GVQDPAAAGPRGPGPHDQIPPNKPPWFDQPH----PVAPWGQQQ 435
           P S   ++  APG   G+Q P+  G  G  P   IP  +PP    PH    P+ P     
Sbjct: 803 PVSLLGTQGVAPGPVIGLQAPST-GLLGARP-GLIPLQRPPGMPPPHLQRFPLMP----- 855

Query: 436 PPEQPPYPHHQGGPPH-----CPPWNNSH-----EGMWGEQRGDPGWNGQRDAPWNNQPD 485
           P   PP+  H+G PP       PP +         G +    G PG  G    P   + D
Sbjct: 856 PRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPE-D 914

Query: 486 AAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFN 545
                Q   P     +QP     Q+    + Q+PP  + P PP QQ PQ  +  +   FN
Sbjct: 915 RDGRQQ---PPQQPQQQPQPQAPQQPQQQQQQQPPPSQQP-PPTQQQPQQFRNDNRQQFN 970

Query: 546 --RFPPRFMQDDFPPRHPFERPPYPHRFD 572
             R   RF +  F  R   +R  Y +R D
Sbjct: 971 SGRDQERFGRRSFGNRVENDRERYGNRND 999



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 16/35 (45%), Positives = 19/35 (54%)

Query: 330 QQQQQQQQQQQQLQMPQMEAEVKATPPPPAPPPAP 364
           QQ  QQ QQQ Q Q PQ   + +   PPP+  P P
Sbjct: 919 QQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 953



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 14/41 (34%), Positives = 21/41 (51%), Gaps = 1/41 (2%)

Query: 78  PAATMPPLPQPPLAPAAPIPPAQGAP-SMDELIQQSQWNLQ 117
           P   +PP P PP+ P   IPP    P S+  L+  ++ N +
Sbjct: 735 PPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAE 775



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 331 QQQQQQQQQQQLQMPQMEAEVKATPPPPAPPPAPAPAP 368
           QQ QQQ Q Q  Q PQ + + +  PPP   PP     P
Sbjct: 923 QQPQQQPQPQAPQQPQQQQQQQ--PPPSQQPPPTQQQP 958


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 95/306 (31%), Positives = 115/306 (37%), Gaps = 46/306 (15%)

Query: 345 PQMEAEVKATPPPPAPPPAPAP----APAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDP 400
           PQ   + +  PPPP  P  P P     P  PP        PP      S    PG  Q P
Sbjct: 41  PQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 100

Query: 401 AAAG---PRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNN 457
              G   P+GP P    PP KP    Q  P  P G  + P+ PP P    GPP     + 
Sbjct: 101 PPQGGNQPQGPPP----PPGKP----QGPP--PQGGNR-PQGPPPPGKPQGPPPQGDKSR 149

Query: 458 SHEGMWGEQRGDPGWNGQRDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQR----EPP 513
           S     G+ +G P   G       NQP      Q   P   + + PP  GG++     PP
Sbjct: 150 SPRSPPGKPQGPPPQGG-------NQP------QGPPPPPGKPQGPPPQGGKKPQGPPPP 196

Query: 514 FRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNR---FPPRFMQDDFPPRHPFERPPYPHR 570
            + Q PP         Q  P   Q P P   N+    PP   +   PP     +P  P  
Sbjct: 197 GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 256

Query: 571 FDYPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQ----PPHM 626
              PQG  PA+ G        R P PG  + PP     +P   PPP G N Q    PP  
Sbjct: 257 PGKPQGP-PAQGGSKSQ--SARSP-PGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAG 312

Query: 627 RRQGPP 632
           + QGPP
Sbjct: 313 QPQGPP 318



 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 75/241 (31%), Positives = 93/241 (38%), Gaps = 36/241 (14%)

Query: 345 PQMEAEVKATPPPPAPPPAPAP----APAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDP 400
           PQ   + +  PPPP  P  P P     P  PP        PP      S    PG  Q P
Sbjct: 102 PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 161

Query: 401 AAAG---PRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNN 457
              G   P+GP P    PP KP    Q  P  P G ++ P+ PP P    GPP     + 
Sbjct: 162 PPQGGNQPQGPPP----PPGKP----QGPP--PQGGKK-PQGPPPPGKPQGPPPQGDKSR 210

Query: 458 SHEGMWGEQRGDPGWNGQR-----DAPWNNQ--PDAAWNSQFEGPWNSQHEQPPWGGGQ- 509
           S +   G+ +G P   G +       P   Q  P    N     P   + + PP  GG  
Sbjct: 211 SSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK 270

Query: 510 ----REPPFRMQRPP-----HFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRH 560
               R PP + Q PP     + +GP PP   +PQ  Q P P    + PPR  Q   P R 
Sbjct: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP-PAGQPQGPPRPPQGGRPSRP 329

Query: 561 P 561
           P
Sbjct: 330 P 330



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 41/134 (30%), Positives = 46/134 (34%), Gaps = 18/134 (13%)

Query: 331 QQQQQQQQQQQLQMPQMEAEVKATPPPPAPPP-----APAPAPAIPPTTQPDDSKP--PI 383
           Q  + +  Q     PQ         P   PPP      P P     P   P   KP  P 
Sbjct: 205 QGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 264

Query: 384 QMPGSSEYEA---PGGVQDPAAAGPRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQP 440
              GS    A   PG  Q P    P+  G + Q PP       Q     P GQ Q P +P
Sbjct: 265 AQGGSKSQSARSPPGKPQGP----PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 320

Query: 441 PYPHHQGGPPHCPP 454
           P    QGG P  PP
Sbjct: 321 P----QGGRPSRPP 330


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 95/307 (30%), Positives = 115/307 (37%), Gaps = 65/307 (21%)

Query: 345 PQMEAEVKATPPPPAPP-------------PAPAPA-PAIPPTTQPDDSKPPIQMPGSSE 390
           PQ   + + TPPPP  P             P P P  P  PP    + S+ P   PG  E
Sbjct: 41  PQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE 100

Query: 391 YEAPGGVQDPAAAGPRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPP 450
            + P G            G   Q PP +P    +P    P G  Q    PP P    GPP
Sbjct: 101 GQPPQG------------GNQSQGPPPRP---GKPEGPPPQGGNQSQGPPPRPGKPEGPP 145

Query: 451 HCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQR 510
             P   N       + +G P   G+ + P    P     SQ   P   + E PP  GG +
Sbjct: 146 --PQGGN-------QSQGPPPRPGKPEGP---PPQGGNQSQGPPPHPGKPEGPPPQGGNQ 193

Query: 511 E--PPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYP 568
              PP R  +P    GP PP   +     PP P      PP   Q    P+ P   PP+P
Sbjct: 194 SQGPPPRPGKP---EGP-PPQGGNQSQGPPPRPGK-PEGPPS--QGGNKPQGP---PPHP 243

Query: 569 HRFDYPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAG--PQHPDFGPPPHGFNGQPPHM 626
            +   PQG  P E   P      R P PG  + PP  G  PQ P   PPP G    PP  
Sbjct: 244 GK---PQGPPPQEGNKPQ-----RPPPPGRPQGPPPPGGNPQQPL--PPPAGKPQGPPPP 293

Query: 627 RRQGPPH 633
            + G PH
Sbjct: 294 PQGGRPH 300



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 41/123 (33%), Positives = 47/123 (38%), Gaps = 21/123 (17%)

Query: 352 KATPPPP-------APPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAA-- 402
           K   PPP        PPP P   P  PP    + S+ P   PG  E     G   P    
Sbjct: 182 KPEGPPPQGGNQSQGPPPRPGK-PEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPP 240

Query: 403 ---AGPRGPGPHDQIPPNKPPWFDQPH-PVAPWGQQQPPEQPPY-------PHHQGGPPH 451
                P+GP P +   P +PP   +P  P  P G  Q P  PP        P  QGG PH
Sbjct: 241 PHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPH 300

Query: 452 CPP 454
            PP
Sbjct: 301 RPP 303


>gi|9558733 transformer-2 alpha [Homo sapiens]
          Length = 282

 Score = 80.9 bits (198), Expect = 5e-15
 Identities = 60/120 (50%), Positives = 73/120 (60%), Gaps = 13/120 (10%)

Query: 727 KGQEKRNSG--PSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSR 784
           +G+E R+    P+ + +R KS  RS SRS SR SK S S+SRSRS+S      RSRSR  
Sbjct: 10  EGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKS------RSRSRRH 63

Query: 785 SRSRSSRSRSRSQS---RSRSKSYSPG-RRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLG 840
           S  R +RSRS S S   RSRS+SY+P  RRRRSRS SP        GS  A P P++ LG
Sbjct: 64  SHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSR-ANPDPNTCLG 122



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 36/102 (35%), Positives = 47/102 (46%)

Query: 701 RPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKS 760
           R   S+     G     +++ R+  R          S SRSRSKSR RS   S+ R ++S
Sbjct: 12  RESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRS 71

Query: 761 SGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRS 802
                  R RS SRSY+    R RSRS S  S  R  + SR+
Sbjct: 72  RSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRA 113



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 39/88 (44%), Positives = 49/88 (55%), Gaps = 16/88 (18%)

Query: 749 SSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSR-------SSRSRSRSQSRS- 800
           S    N+   + S S S+S + + +R  S SRS SRS SR        SRSRS+S+SRS 
Sbjct: 2   SDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSR 61

Query: 801 --------RSKSYSPGRRRRSRSRSPTP 820
                   RS+S+S   RRRSRSRS TP
Sbjct: 62  RHSHRRYTRSRSHSHSHRRRSRSRSYTP 89



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 18/26 (69%), Positives = 18/26 (69%)

Query: 766 RSRSRSCSRSYSRSRSRSRSRSRSSR 791
           R R RS S  YSR RSRSRSRS S R
Sbjct: 255 RYRRRSPSPYYSRYRSRSRSRSYSPR 280



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 24/54 (44%), Positives = 26/54 (48%), Gaps = 6/54 (11%)

Query: 762 GSYSRSRSRSCSRSYSRSRSRS-----RSRSRS-SRSRSRSQSRSRSKSYSPGR 809
           G   R R     R Y R   R      R R RS S   SR +SRSRS+SYSP R
Sbjct: 228 GGGGRRRDSYYDRGYDRGYDRYEDYDYRYRRRSPSPYYSRYRSRSRSRSYSPRR 281


>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
           sapiens]
          Length = 375

 Score = 80.1 bits (196), Expect = 9e-15
 Identities = 62/142 (43%), Positives = 77/142 (54%), Gaps = 21/142 (14%)

Query: 698 SHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSR-----SKSRGRSSSR 752
           S D+ R      +NG       + R +R++ +  R    SRSRSR     S+SR R  SR
Sbjct: 35  SSDKGRERLNSSENG-------EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSR 87

Query: 753 SNSRSSKSSGSYSRSRSRSCSRSYSRSRS-RSRSRSRS-----SRSRSRSQSRSRSKS-- 804
           S SR  K S S SR R +S SRS  R R  RSRSRSRS     +RSRSR++SRSR +   
Sbjct: 88  SRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR 147

Query: 805 -YSPGRRRRSRSRSPTPPSSAG 825
              P R  RS SR+P+PP   G
Sbjct: 148 IEKPRRFSRSLSRTPSPPPFRG 169



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 44/104 (42%), Positives = 54/104 (51%), Gaps = 6/104 (5%)

Query: 719 AKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSR 778
           +K         ++ +S   R R  S   G    +   R S    S+SRSRSR   R  SR
Sbjct: 21  SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE-RRHRSR 79

Query: 779 SRSRSRSRSRS-----SRSRSRSQSRSRSKSYSPGRRRRSRSRS 817
           SR R +SRSRS     SRSRSR + +SRS+S    RR RSRSRS
Sbjct: 80  SRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS 123



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 35/101 (34%), Positives = 48/101 (47%), Gaps = 5/101 (4%)

Query: 722 RARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRS 781
           + RR + ++K +          K       R    SS++     + + R  SR  S SRS
Sbjct: 10  QGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS 69

Query: 782 RSRSRSRSSRSRSRSQSRSRSKSYSPGR-----RRRSRSRS 817
           RSR R   SRSR R +SRSRS+     R     R++SRSRS
Sbjct: 70  RSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRS 110



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 15/108 (13%)

Query: 698 SHDRPRNSEGWEQNGLYEFFRAKMRARRRK---------------GQEKRNSGPSRSRSR 742
           SH R R+ E   ++   E  +++ R+R RK                +E++    SRSRSR
Sbjct: 65  SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 124

Query: 743 SKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSS 790
           S+ R R+ SRS +RS          + R  SRS SR+ S    R R++
Sbjct: 125 SRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 172



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 28/75 (37%), Positives = 41/75 (54%), Gaps = 1/75 (1%)

Query: 718 RAKMRARRRKGQEK-RNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSY 776
           R K R+R R+ + + R+   SRSR R ++R RS +RS SR  K      R  SRS SR+ 
Sbjct: 103 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTP 162

Query: 777 SRSRSRSRSRSRSSR 791
           S    R R+ +  ++
Sbjct: 163 SPPPFRGRNTAMDAQ 177



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 6/90 (6%)

Query: 720 KMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRS------RSRSCS 773
           K R R R     R+   +RSRSR++SR R   +   +  + S S SR+      R R+ +
Sbjct: 114 KRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTA 173

Query: 774 RSYSRSRSRSRSRSRSSRSRSRSQSRSRSK 803
                + +R   R++  + +   +   + K
Sbjct: 174 MDAQEALARRLERAKKLQEQREKEMVEKQK 203


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 80.1 bits (196), Expect = 9e-15
 Identities = 62/142 (43%), Positives = 77/142 (54%), Gaps = 21/142 (14%)

Query: 698 SHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSR-----SKSRGRSSSR 752
           S D+ R      +NG       + R +R++ +  R    SRSRSR     S+SR R  SR
Sbjct: 94  SSDKGRERLNSSENG-------EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSR 146

Query: 753 SNSRSSKSSGSYSRSRSRSCSRSYSRSRS-RSRSRSRS-----SRSRSRSQSRSRSKS-- 804
           S SR  K S S SR R +S SRS  R R  RSRSRSRS     +RSRSR++SRSR +   
Sbjct: 147 SRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR 206

Query: 805 -YSPGRRRRSRSRSPTPPSSAG 825
              P R  RS SR+P+PP   G
Sbjct: 207 IEKPRRFSRSLSRTPSPPPFRG 228



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 44/104 (42%), Positives = 54/104 (51%), Gaps = 6/104 (5%)

Query: 719 AKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSR 778
           +K         ++ +S   R R  S   G    +   R S    S+SRSRSR   R  SR
Sbjct: 80  SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE-RRHRSR 138

Query: 779 SRSRSRSRSRS-----SRSRSRSQSRSRSKSYSPGRRRRSRSRS 817
           SR R +SRSRS     SRSRSR + +SRS+S    RR RSRSRS
Sbjct: 139 SRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS 182



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 45/132 (34%), Positives = 60/132 (45%), Gaps = 28/132 (21%)

Query: 714 YEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNS------------------ 755
           + + R++ R+R RK +        RSRSRSK   R  S+  S                  
Sbjct: 38  HHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDK 97

Query: 756 -----RSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGR- 809
                 SS++     + + R  SR  S SRSRSR R   SRSR R +SRSRS+     R 
Sbjct: 98  GRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRS 157

Query: 810 ----RRRSRSRS 817
               R++SRSRS
Sbjct: 158 RSRERKKSRSRS 169



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 45/141 (31%), Positives = 55/141 (39%), Gaps = 48/141 (34%)

Query: 724 RRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRS------------ 771
           R +K ++   S   R+     SR RS SR   R S + G   RSRSRS            
Sbjct: 20  RDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKS 79

Query: 772 -----------------------------------CSRSYSRSRSRSRSRSRSSRSRSRS 796
                                                R  SR RS SRSRSR  R RSRS
Sbjct: 80  SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRS 139

Query: 797 QSRSRSKSYSPGRRRRSRSRS 817
           + R +S+S S   R++SRSRS
Sbjct: 140 RERKKSRSRS-RERKKSRSRS 159



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 15/108 (13%)

Query: 698 SHDRPRNSEGWEQNGLYEFFRAKMRARRRK---------------GQEKRNSGPSRSRSR 742
           SH R R+ E   ++   E  +++ R+R RK                +E++    SRSRSR
Sbjct: 124 SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSR 183

Query: 743 SKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSS 790
           S+ R R+ SRS +RS          + R  SRS SR+ S    R R++
Sbjct: 184 SRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 231



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 28/75 (37%), Positives = 41/75 (54%), Gaps = 1/75 (1%)

Query: 718 RAKMRARRRKGQEK-RNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSY 776
           R K R+R R+ + + R+   SRSR R ++R RS +RS SR  K      R  SRS SR+ 
Sbjct: 162 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTP 221

Query: 777 SRSRSRSRSRSRSSR 791
           S    R R+ +  ++
Sbjct: 222 SPPPFRGRNTAMDAQ 236



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 9/100 (9%)

Query: 726 RKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRS 785
           R G     + P R + + +S    S R+      S   YSRSRSRS  R   + +S +  
Sbjct: 8   RDGLAPEKTSPDRDKKKEQSEVSVSPRA------SKHHYSRSRSRSRER---KRKSDNEG 58

Query: 786 RSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAG 825
           R   SRSRS+   R  SK  S  + +          S  G
Sbjct: 59  RKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKG 98



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 6/90 (6%)

Query: 720 KMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRS------RSRSCS 773
           K R R R     R+   +RSRSR++SR R   +   +  + S S SR+      R R+ +
Sbjct: 173 KRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTA 232

Query: 774 RSYSRSRSRSRSRSRSSRSRSRSQSRSRSK 803
                + +R   R++  + +   +   + K
Sbjct: 233 MDAQEALARRLERAKKLQEQREKEMVEKQK 262


>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo
           sapiens]
          Length = 1792

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 92/256 (35%), Positives = 112/256 (43%), Gaps = 59/256 (23%)

Query: 579 PAEMGPPHHHPGHRMP-HPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHD 637
           P  + PP   P H +P  PG+   PP   PQ P   PPP G++  PP      PP     
Sbjct: 561 PPPLYPP---PPHTLPLPPGVP--PPQFSPQFPPGQPPPAGYSVPPPGF----PP----- 606

Query: 638 DPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPP 697
                        PA L  P V               + PP          + E FY   
Sbjct: 607 ------------APANLSTPWVSSGVQTAHSNTIPTTQAPP---------LSREEFYR-- 643

Query: 698 SHDRPRNSEGWEQNGLYEFFR--AKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNS 755
              R    E  +++ L EF    AK     +K Q++R    S SRS+S   G S SRS+ 
Sbjct: 644 -EQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRR--SFSRSKSPYSGSSYSRSSY 700

Query: 756 RSSKS-SGSYSRSRSRSCSRSYSRSRSRS-----------RSRSRSSRSRSRSQSRSRSK 803
             SKS SGS   +RSRS SRS+SRS SRS           R +SR+ RSRSRS    RS+
Sbjct: 701 TYSKSRSGS---TRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSR 757

Query: 804 SYSPG-RRRRSRSRSP 818
           S SP  RR  SRSRSP
Sbjct: 758 SRSPPYRRYHSRSRSP 773



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 71/249 (28%), Positives = 98/249 (39%), Gaps = 61/249 (24%)

Query: 583 GPPHHHPGHRMPHPGINEHPPWAG-PQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSL 641
           G  H     R   P +   P +   P  P + PPPH     PP +    PP  +   P  
Sbjct: 535 GRHHSERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLP-LPPGVP---PPQFS---PQF 587

Query: 642 VPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAA------VEAFYS 695
            P  P    PAG   P                   PP  PP+   L+       V+  +S
Sbjct: 588 PPGQPP---PAGYSVP-------------------PPGFPPAPANLSTPWVSSGVQTAHS 625

Query: 696 ---PPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSR 752
              P +   P + E        EF+R +   RR K +EK+ S   +    +    +    
Sbjct: 626 NTIPTTQAPPLSRE--------EFYREQ---RRLKEEEKKKS---KLDEFTNDFAKELME 671

Query: 753 SNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRR 812
                 +   S+SRS+S     SYSRS S + S+SRS  +RSRS SRS S+S+S      
Sbjct: 672 YKKIQKERRRSFSRSKSPYSGSSYSRS-SYTYSKSRSGSTRSRSYSRSFSRSHS------ 724

Query: 813 SRSRSPTPP 821
            RS S +PP
Sbjct: 725 -RSYSRSPP 732



 Score = 33.5 bits (75), Expect = 0.93
 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 5/69 (7%)

Query: 735  GPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRS 794
            G SR++S S     S S S SRS   SGS +RS S S S + S+   + + +    + + 
Sbjct: 1686 GISRNQSHS-----SPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKK 1740

Query: 795  RSQSRSRSK 803
              + +   K
Sbjct: 1741 HKKHKKHKK 1749



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 24/81 (29%), Positives = 31/81 (38%), Gaps = 4/81 (4%)

Query: 330 QQQQQQQQQQQQLQMPQMEAEVKATPPPPAPPPAPAPAPAIPPTTQPDDSKP--PIQMPG 387
           +   ++ Q+ Q   +P     V   PPP  PPP P   P +PP   P    P  P   P 
Sbjct: 536 RHHSERSQRTQGPSLPATPVFVPVPPPPLYPPP-PHTLP-LPPGVPPPQFSPQFPPGQPP 593

Query: 388 SSEYEAPGGVQDPAAAGPRGP 408
            + Y  P     PA A    P
Sbjct: 594 PAGYSVPPPGFPPAPANLSTP 614



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 18/46 (39%), Positives = 21/46 (45%), Gaps = 8/46 (17%)

Query: 357 PPAPPPAPAPAPAIPPTTQPDDSKP------PIQMP--GSSEYEAP 394
           PP PPP P P P I    QP    P      P+ +P   SS + AP
Sbjct: 337 PPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAP 382



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 16/88 (18%), Positives = 38/88 (43%)

Query: 729  QEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSR 788
            + + +S PS S SRS S   S +RS+S S+ S+ S    + +         + +   + +
Sbjct: 1689 RNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHK 1748

Query: 789  SSRSRSRSQSRSRSKSYSPGRRRRSRSR 816
                      +S+   +   + ++++ +
Sbjct: 1749 KHAGTEVELEKSQKHKHKKKKSKKNKDK 1776


>gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]
          Length = 272

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 51/82 (62%), Positives = 58/82 (70%), Gaps = 1/82 (1%)

Query: 737 SRSRSRSKSRGRSSSRSNSRS-SKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSR 795
           SRSRSRS+SR RSSSRS SRS S+S  SYSRSRSRS SRS S+SRS SRS       +  
Sbjct: 184 SRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG 243

Query: 796 SQSRSRSKSYSPGRRRRSRSRS 817
           S SRS+S +    +R RSRSRS
Sbjct: 244 SSSRSKSPASVDRQRSRSRSRS 265



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 48/94 (51%), Positives = 59/94 (62%), Gaps = 3/94 (3%)

Query: 744 KSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSK 803
           K  G+  +    +  + S  +SRSRSRS SR+ S SRSRSRSRSRS +S SRS+SRSRS+
Sbjct: 163 KLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSR 222

Query: 804 SYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDS 837
           S S   + RS SRSP P  S   GS+S    P S
Sbjct: 223 SRS---KSRSVSRSPVPEKSQKRGSSSRSKSPAS 253



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 36/74 (48%), Positives = 40/74 (54%), Gaps = 17/74 (22%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRS-----SKSSGSYSRS----- 767
           R+  R+R R     R S  SRSRSRS+SR RS SRS SRS     S+  GS SRS     
Sbjct: 195 RSSSRSRSRSRSRSRKSY-SRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPAS 253

Query: 768 ------RSRSCSRS 775
                 RSRS SRS
Sbjct: 254 VDRQRSRSRSRSRS 267


>gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]
          Length = 272

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 51/82 (62%), Positives = 58/82 (70%), Gaps = 1/82 (1%)

Query: 737 SRSRSRSKSRGRSSSRSNSRS-SKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSR 795
           SRSRSRS+SR RSSSRS SRS S+S  SYSRSRSRS SRS S+SRS SRS       +  
Sbjct: 184 SRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG 243

Query: 796 SQSRSRSKSYSPGRRRRSRSRS 817
           S SRS+S +    +R RSRSRS
Sbjct: 244 SSSRSKSPASVDRQRSRSRSRS 265



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 48/94 (51%), Positives = 59/94 (62%), Gaps = 3/94 (3%)

Query: 744 KSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSK 803
           K  G+  +    +  + S  +SRSRSRS SR+ S SRSRSRSRSRS +S SRS+SRSRS+
Sbjct: 163 KLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSR 222

Query: 804 SYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDS 837
           S S   + RS SRSP P  S   GS+S    P S
Sbjct: 223 SRS---KSRSVSRSPVPEKSQKRGSSSRSKSPAS 253



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 36/74 (48%), Positives = 40/74 (54%), Gaps = 17/74 (22%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRS-----SKSSGSYSRS----- 767
           R+  R+R R     R S  SRSRSRS+SR RS SRS SRS     S+  GS SRS     
Sbjct: 195 RSSSRSRSRSRSRSRKSY-SRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPAS 253

Query: 768 ------RSRSCSRS 775
                 RSRS SRS
Sbjct: 254 VDRQRSRSRSRSRS 267


>gi|50083281 KIAA1853 protein [Homo sapiens]
          Length = 611

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 70/175 (40%), Positives = 85/175 (48%), Gaps = 22/175 (12%)

Query: 678 PPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKG-----QEKR 732
           PP   S    +   + YSP     P+ SE   Q       R + RARRR+      +++R
Sbjct: 444 PPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQ------RERERARRRRRSYSPMRKRR 497

Query: 733 NSGPSRSRSRSKSRGR---------SSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRS 783
              PS   +R  +  R         S S S S SS SS  YS S SRS SRSYSRSRSRS
Sbjct: 498 RDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSW-YSSSSSRSASRSYSRSRSRS 556

Query: 784 RSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSR 838
           RSR RS R+R+ S S SRS S     R RSRSRS +   S     +SA     +R
Sbjct: 557 RSRRRS-RTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTR 610



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 54/142 (38%), Positives = 67/142 (47%), Gaps = 8/142 (5%)

Query: 722 RARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRS 781
           RA  R  Q +  S   RS SRS S    SS+S  RS  S  S SR RS S SR YS SR 
Sbjct: 411 RASPRYTQSRSTSSEKRSYSRSPSY---SSKSGKRSPPSRSSRSR-RSPSYSR-YSPSRE 465

Query: 782 RSRSRS-RSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLG 840
           R    S + S+ R R ++R R +SYSP R+R  R  SP+   +  + S    PIP  R  
Sbjct: 466 RDPKYSEKDSQQRERERARRRRRSYSPMRKR--RRDSPSHLEARRITSARKRPIPYYRPS 523

Query: 841 EENKGHQMLVKMGWSGSGGLGA 862
             + G        +S S    A
Sbjct: 524 PSSSGSLSSTSSWYSSSSSRSA 545



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 55/148 (37%), Positives = 66/148 (44%), Gaps = 14/148 (9%)

Query: 695 SPPSHD-RPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRS 753
           SPPS   R R S  + +        +  R R  K  EK +    R R+R + R  S  R 
Sbjct: 443 SPPSRSSRSRRSPSYSRY-------SPSRERDPKYSEKDSQQRERERARRRRRSYSPMRK 495

Query: 754 NSRSSKSSGSYSR--SRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGR-R 810
             R S S     R  S  +     Y  S S S S S +S   S S SRS S+SYS  R R
Sbjct: 496 RRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSR 555

Query: 811 RRSRSRSPTPPSSAGLGSNSAPPIPDSR 838
            RSR RS T  SS+   S+S  P P SR
Sbjct: 556 SRSRRRSRTRTSSS---SSSRSPSPGSR 580



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 42/133 (31%), Positives = 55/133 (41%), Gaps = 17/133 (12%)

Query: 718 RAKMRARRRKGQEKRNSGPS----RSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCS 773
           + K ++ R+K +   +  PS    + +  SK   R  S S  R   SS   S+ R     
Sbjct: 110 KKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRH 169

Query: 774 RSYSRSRSRSRSRSRSSRSRSRSQS--------RSRSKSYSP-----GRRRRSRSRSPTP 820
           +  SRSR R   R R  R  SRSQS         SR +  SP      RRR SR  S T 
Sbjct: 170 KKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTL 229

Query: 821 PSSAGLGSNSAPP 833
              +    +S PP
Sbjct: 230 CKDSPEAQSSRPP 242



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 33/110 (30%), Positives = 51/110 (46%), Gaps = 2/110 (1%)

Query: 730 EKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRS 789
           +K  + P  SR + K + +S+ +   RSS  S S  + + +  S+ + R RS S+ R  S
Sbjct: 97  DKDLTPPPSSRGKKKKK-KSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHS 155

Query: 790 SRS-RSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSR 838
           S S +S+ +   R K  S  R R+S         S    S S P   +SR
Sbjct: 156 SSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESR 205



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 39/95 (41%), Positives = 50/95 (52%), Gaps = 5/95 (5%)

Query: 730 EKRNSGPSRSRSRS-KSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSR 788
           +K +  PS +RS   K   RSSS +++RSS  S   SRS +   S  Y++SRS S  +  
Sbjct: 372 KKSSLVPSTARSSPMKGCSRSSSYASTRSSSHS---SRSPNPRASPRYTQSRSTSSEKRS 428

Query: 789 SSRSRS-RSQSRSRSKSYSPGRRRRSRSRSPTPPS 822
            SRS S  S+S  RS      R RRS S S   PS
Sbjct: 429 YSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPS 463



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 43/147 (29%), Positives = 55/147 (37%), Gaps = 33/147 (22%)

Query: 719 AKMRARRRKGQEKRNSGPS----------RSRSRSKSRGRSSSRSNSRSSKSSGSYSRSR 768
           +K   RRR   +KR    S          R + +S+SR R S R       S    S SR
Sbjct: 139 SKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESR 198

Query: 769 SRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPP------- 821
             SC      SR R RS     +SR R  SR  SK+          SR P+ P       
Sbjct: 199 PSSC-----ESRHRGRSPEEGQKSR-RRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYL 252

Query: 822 ----------SSAGLGSNSAPPIPDSR 838
                     S+A L + +A P+  SR
Sbjct: 253 SARGVITGSGSAADLFTKTASPLTTSR 279



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 6/94 (6%)

Query: 727 KGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSR 786
           +G++K+     + R RS S   S S    +  KSS  + R RS S  R +S S  +S+ R
Sbjct: 107 RGKKKKKKSTRKKRRRSSSY--SPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRR 164

Query: 787 SRS---SRSRSRSQSRSRSKSY-SPGRRRRSRSR 816
                  +SRSR +   R + +  P R + S SR
Sbjct: 165 DEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESR 198



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 50/181 (27%), Positives = 68/181 (37%), Gaps = 40/181 (22%)

Query: 695 SPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSN 754
           SP +  R R+ E    N        +  + R +GQEK +     S+SR  + G +S   N
Sbjct: 273 SPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGN 332

Query: 755 S---------------RSSKSSGSYSRSRSRSC--------------------SRSYSRS 779
           S                S  S G  SR     C                     +  SRS
Sbjct: 333 SFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRS 392

Query: 780 RSR--SRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDS 837
            S   +RS S SSRS +   S   ++S S    +RS SRSP+  S +G     +PP   S
Sbjct: 393 SSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSG---KRSPPSRSS 449

Query: 838 R 838
           R
Sbjct: 450 R 450



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 20/74 (27%), Positives = 34/74 (45%), Gaps = 1/74 (1%)

Query: 747 GRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYS 806
           G S       +++  G+ S  R ++C R    +R  S S  +       S+ + + K  +
Sbjct: 58  GPSEKLGQHLATEPLGTNSWERDKTC-RELGATRGHSASHDKDLTPPPSSRGKKKKKKST 116

Query: 807 PGRRRRSRSRSPTP 820
             +RRRS S SP+P
Sbjct: 117 RKKRRRSSSYSPSP 130


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 77.0 bits (188), Expect = 7e-14
 Identities = 54/132 (40%), Positives = 77/132 (58%), Gaps = 12/132 (9%)

Query: 697 PSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSR 756
           P   R R+++ W ++   +  R + R+ +R G  +  +   R RSRS  RGRS SRS + 
Sbjct: 511 PQWRRSRSAQRWGRSRSPQR-RGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPAT 569

Query: 757 SSKS----------SGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYS 806
             +S          S S + +R RS SR+ +R RSRSR+ +R  RSRSR+ +R RS++ S
Sbjct: 570 RGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRS 629

Query: 807 PGRRRRSRSRSP 818
           P  RRRSRSRSP
Sbjct: 630 P-VRRRSRSRSP 640



 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 61/158 (38%), Positives = 81/158 (51%), Gaps = 21/158 (13%)

Query: 701  RPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKS 760
            R R   G+          ++  +RRR+G+  R    SR RSRS++      RS SR+S +
Sbjct: 1813 RRRGGSGYHSRSPARQESSRTSSRRRRGRS-RTPPTSRKRSRSRTSPAPWKRSRSRASPA 1871

Query: 761  SGSYSRSRSRSCSRSYSRSR----SRSRSRSRSSRSRSRSQSR----SRSKSYS---PGR 809
            +   SRSR+   SR  SRSR    SR RSRSR+S +R RS+SR    SR +S S   P  
Sbjct: 1872 THRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVT 1931

Query: 810  RRRSRSRSP---------TPPSSAGLGSNSAPPIPDSR 838
            RRRSRSR+P         TPP +     +  PP+   R
Sbjct: 1932 RRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRR 1969



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 50/117 (42%), Positives = 64/117 (54%), Gaps = 4/117 (3%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSG-SYSRS---RSRSCS 773
           R + R+R    +  R   P R RSRS+S  R S RS SR+    G S SR+   R RS S
Sbjct: 612 RGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRS 671

Query: 774 RSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNS 830
           R+ +R   RSRSR+ + R RSRS++  R +S S    RR RS S TP      GS+S
Sbjct: 672 RTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSS 728



 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 63/162 (38%), Positives = 87/162 (53%), Gaps = 26/162 (16%)

Query: 695 SPPSHDRPRNSE--GWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKS---RGRS 749
           SP    R R+ +  GW ++   +  R + R+ RR G+    S  +R RSRS++   RGRS
Sbjct: 527 SPQRRGRSRSPQRPGWSRSRNTQR-RGRSRSARR-GRSHSRSPATRGRSRSRTPARRGRS 584

Query: 750 SSRSNSRSSKSSGSYSRSRSRSCS-----RSYSRSRSRSRSRSRSS---RSRSRSQSR-- 799
            SR+ +R    S + +R RSRS +     RS SR+ +R RSR+RS    RSRSRS +R  
Sbjct: 585 RSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRS 644

Query: 800 SRSKSYSPGRR---------RRSRSRSPTPPSSAGLGSNSAP 832
            RS+S +P RR         RR RSRS TP   +G   +  P
Sbjct: 645 GRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTP 686



 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 58/157 (36%), Positives = 79/157 (50%), Gaps = 11/157 (7%)

Query: 668 PLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRK 727
           P  PK    P P P S R +++     +  SH R +  +           R++  A  ++
Sbjct: 438 PESPK----PAPAPGSHREISSSPTSKNR-SHGRAKRDKSHSHTPSRRMGRSRSPATAKR 492

Query: 728 GQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSR-SYSRSRS---RS 783
           G+ +  +   R  SRS+S     SRS  R  +S     R RSRS  R  +SRSR+   R 
Sbjct: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRG 552

Query: 784 RSRS-RSSRSRSRSQS-RSRSKSYSPGRRRRSRSRSP 818
           RSRS R  RS SRS + R RS+S +P RR RSRSR+P
Sbjct: 553 RSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTP 589



 Score = 70.1 bits (170), Expect = 9e-12
 Identities = 56/149 (37%), Positives = 79/149 (53%), Gaps = 16/149 (10%)

Query: 699 HDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRS- 757
           H R R+ +         + R++   RR + +  +  G SRSR+  + RGRS S    RS 
Sbjct: 505 HSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQR-RGRSRSARRGRSH 563

Query: 758 SKSSGSYSRSRSRS-CSRSYSRSRSRSRSRSRS---SRSRSRSQS---RSRSKSYSPGRR 810
           S+S  +  RSRSR+   R  SRSR+ +R RSRS   +R RSRS++   R RS+S +P RR
Sbjct: 564 SRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARR 623

Query: 811 R-------RSRSRSPTPPSSAGLGSNSAP 832
           R       R RSRS +P   +G   +  P
Sbjct: 624 RSRTRSPVRRRSRSRSPARRSGRSRSRTP 652



 Score = 70.1 bits (170), Expect = 9e-12
 Identities = 62/169 (36%), Positives = 83/169 (49%), Gaps = 26/169 (15%)

Query: 675  RLPPPMPPS---ERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEK 731
            R P P P      R  +  E   +    DR  +S+   +       R+++  RRR G   
Sbjct: 1761 RSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGY 1820

Query: 732  RNSGPSRS--------RSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSR- 782
             +  P+R         R R +SR   +SR  SRS  S   + RSRSR+   ++ RSRSR 
Sbjct: 1821 HSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRT 1880

Query: 783  ---SRSRSRS-----SRSRSRSQS-----RSRSKSYSPGRRRRSRSRSP 818
               SR RSRS     SR RSRS++     RSRS++ SP  RRRSRSR+P
Sbjct: 1881 PLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA-SPVSRRRSRSRTP 1928



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 47/124 (37%), Positives = 65/124 (52%), Gaps = 6/124 (4%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYS 777
           R++ R   R+G+ +  +   R RSRS++  R S RS SR+    G   RSRSR+  R  S
Sbjct: 646 RSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRG---RSRSRTPRRGRS 702

Query: 778 RSRS---RSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPI 834
           RSRS   R RS SR+ + R RS S S  K+ S   +RRSRS S      + + S  +  +
Sbjct: 703 RSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL 762

Query: 835 PDSR 838
              R
Sbjct: 763 SSPR 766



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 61/154 (39%), Positives = 74/154 (48%), Gaps = 20/154 (12%)

Query: 695  SPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRS---KSRGRSSS 751
            +PP H R  +    E        +++   RRR     R    SR R RS   K RG   S
Sbjct: 1720 TPPRHRRSPSVSSPEPAE-----KSRSSRRRRSASSPRTKTTSR-RGRSPSPKPRGLQRS 1773

Query: 752  RSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSR-------SRSQSRSRSKS 804
            RS SR  K+  +  R RS S S+S SR R RSRSRSR +R R       SRS +R  S S
Sbjct: 1774 RSRSRREKTRTTRRRDRSGS-SQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQES-S 1831

Query: 805  YSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSR 838
             +  RRRR RSR  TPP+S     +   P P  R
Sbjct: 1832 RTSSRRRRGRSR--TPPTSRKRSRSRTSPAPWKR 1863



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 56/151 (37%), Positives = 76/151 (50%), Gaps = 15/151 (9%)

Query: 701  RPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKS 760
            R R+  G  Q+      R++ R+R  + +   +   SRS +R +S   SS R   RS   
Sbjct: 1786 RRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTP 1845

Query: 761  SGSYSRSRSRSCSRSYSRSRSRS------RSRSRS---SRSRSRSQ----SRSRSKSYSP 807
              S  RSRSR+    + RSRSR+      RSRSR+   SR RSRS+    SR RS+S + 
Sbjct: 1846 PTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTS 1905

Query: 808  GRRRRSRSRSPTPPSSAGLGSNSAPPIPDSR 838
              RRRSRSR+   P S     +  PP+   R
Sbjct: 1906 VTRRRSRSRA--SPVSRRRSRSRTPPVTRRR 1934



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 53/133 (39%), Positives = 69/133 (51%), Gaps = 17/133 (12%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRS-----RSKSR-----GRSSSRSNSRSSKSSGSYSRS 767
           R+ +R R R     R SG SRSR+     RS+SR     GRS SR+ +R S  S S + +
Sbjct: 628 RSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA 687

Query: 768 R-SRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGL 826
           R  RS SR+  R RSRSRS  R  RS SR+  R      S  R+ +SR+      S    
Sbjct: 688 RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRT------SQRRS 741

Query: 827 GSNSAPPIPDSRL 839
            SNS+P +  SR+
Sbjct: 742 RSNSSPEMKKSRI 754



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 54/158 (34%), Positives = 75/158 (47%), Gaps = 9/158 (5%)

Query: 681  PPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSR 740
            PP+ R  +      +P    R R S    +       R++     R+    R S  SR R
Sbjct: 1845 PPTSRKRSRSRTSPAPWKRSRSRASPATHRRS-----RSRTPLISRRRSRSRTSPVSRRR 1899

Query: 741  SRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRS 800
            SRS++   S +R  SRS  S  S  RSRSR+   +  RSRSR+ +  R SRSR+   +R 
Sbjct: 1900 SRSRT---SVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRR 1956

Query: 801  RSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSR 838
            RS+S +P   RR RSRS T P +     +   P+   R
Sbjct: 1957 RSRSRTPPVTRR-RSRSRTSPITRRRSRSRTSPVTRRR 1993



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 61/159 (38%), Positives = 77/159 (48%), Gaps = 23/159 (14%)

Query: 681 PPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSG-PSRS 739
           PPS +         S P   +P  + G  +  +     +K R+  R  ++K +S  PSR 
Sbjct: 422 PPSPQPTKVSRHASSSPESPKPAPAPGSHRE-ISSSPTSKNRSHGRAKRDKSHSHTPSRR 480

Query: 740 RSRSKS-----RGRSSSR-------SNSRS-----SKSSGSYSRSRSRSCSRSYSRSRSR 782
             RS+S     RGRS SR       S SRS     S+S+  + RSRS    R  SRS  R
Sbjct: 481 MGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQ-RRGRSRSPQR 539

Query: 783 ---SRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSP 818
              SRSR+   R RSRS  R RS S SP  R RSRSR+P
Sbjct: 540 PGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTP 578



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 56/146 (38%), Positives = 72/146 (49%), Gaps = 33/146 (22%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKS---RGRSSSR----------SNSRSSKSSGSY 764
           R++ R   R+G+  R+  P R RSRS+S   RGRS SR          S+ R +KS  S 
Sbjct: 680 RSRSRTPARRGRS-RSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQ 738

Query: 765 SRSRSRSC------------SRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRR 812
            RSRS S             SRS S  RS+++SR    RS S S    + KS +P RR R
Sbjct: 739 RRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSR 798

Query: 813 SRSRSP-----TPPSSAGLGSNSAPP 833
           S S  P     TPP  +   S+S+PP
Sbjct: 799 SGSSQPKAKSRTPPRRS--RSSSSPP 822



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 51/137 (37%), Positives = 68/137 (49%), Gaps = 20/137 (14%)

Query: 718  RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYS 777
            R++     R+    R S  +R RSRS++   +  RS SR+S  +   SRSR+    R  S
Sbjct: 1971 RSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRS 2030

Query: 778  RSRS----RSRSRSRSS-----RSRSRSQSRSRSKSY----SPGRRRRS-------RSRS 817
            RSR+    R RSRSRS      RSRSR+   +R K       P  RRRS       RSRS
Sbjct: 2031 RSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRS 2090

Query: 818  PTPPSSAGLGSNSAPPI 834
             TPP++     +  PP+
Sbjct: 2091 ATPPATRNHSGSRTPPV 2107



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 61/174 (35%), Positives = 81/174 (46%), Gaps = 31/174 (17%)

Query: 695  SPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRS- 753
            SP +H R R+              + +  RR + +       SRSR+   SR RS SR+ 
Sbjct: 1869 SPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTP 1928

Query: 754  --NSRSSKSSGSYSRSRSRSCSRSYSRSRSRSR--------SRSRSS-----RSRSRS-- 796
                R S+S    +R RSRS +   +R RSRSR        SRSR+S     RSRSR+  
Sbjct: 1929 PVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSP 1988

Query: 797  --QSRSRSKSYSPGRRRRSRSR----------SPTPPSSAGLGSNSAPPIPDSR 838
              + RSRS++ SP  RRRSRSR          S TPP+      +  P +P  R
Sbjct: 1989 VTRRRSRSRT-SPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKR 2041



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 49/135 (36%), Positives = 65/135 (48%), Gaps = 23/135 (17%)

Query: 718 RAKMRARRRKGQEKRNSGPSR---SRSRSKSRGRSSSRS-------NSRSSKSSGSYSRS 767
           R++ R   R+    R+  P+R   SRSR+  RGRS SRS       +SR+ +  G    S
Sbjct: 668 RSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSS 727

Query: 768 RSRSCSRSYSRSRSRSRS-----RSRSSRSRSRSQSRSRSKSYSPGRRRRS--------R 814
             R      S+ RSRS S     +SR S  RSRS S  RSK+ S    RRS        +
Sbjct: 728 SERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPK 787

Query: 815 SRSPTPPSSAGLGSN 829
            +S TPP  +  GS+
Sbjct: 788 QKSQTPPRRSRSGSS 802



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 42/106 (39%), Positives = 52/106 (49%), Gaps = 10/106 (9%)

Query: 724  RRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRS 783
            R+R+     +S  S S S S S   SSS S+S SS SS S S S S S ++   ++  + 
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662

Query: 784  RS---------RSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTP 820
             S         RSRS R    S   SRS SYSP  RRR  S  P+P
Sbjct: 2663 ASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRP-SPQPSP 2707



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 41/97 (42%), Positives = 54/97 (55%), Gaps = 10/97 (10%)

Query: 736  PSRSRSRSKSRGRSSSRSNSRSSKSSGSYS-RSRS-RSCSRSYSRSRSRSRS--RSRSSR 791
            P RSRS S S+GR  S   S S++SS  +  +SR+ R  SRS    +++SR+  R RSSR
Sbjct: 1633 PRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSR 1692

Query: 792  S------RSRSQSRSRSKSYSPGRRRRSRSRSPTPPS 822
            S      ++R   RSRS S SP  R R+  R    PS
Sbjct: 1693 SSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPS 1729



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 6/113 (5%)

Query: 725 RRKGQEKRNSGPSRSRSRSKSRGRSSSRS------NSRSSKSSGSYSRSRSRSCSRSYSR 778
           +R+ +E +   P   +  S  R  SSSRS        +  K  G  S S S    R  S 
Sbjct: 154 QRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSS 213

Query: 779 SRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSA 831
            + + RS S S + + RS +    +     +R+RSRS +P P S     S SA
Sbjct: 214 KKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSA 266



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 7/123 (5%)

Query: 720 KMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRS 779
           K + ++ +G+   +S P R R +S  + +  S S S+  K      +S+ +S      + 
Sbjct: 189 KKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKS------KD 242

Query: 780 RSRSRSRSRSSRSRSRSQSRSRSK-SYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSR 838
           + R RSRS +   +SR   RS S  S S     RSRSRS    +     +  +P     R
Sbjct: 243 KKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGR 302

Query: 839 LGE 841
            GE
Sbjct: 303 RGE 305



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 1/99 (1%)

Query: 720  KMRARRRKGQEKRNSGPSRSR-SRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSR 778
            K ++R    +    S P  +R +R   R RS+S S    S++   + RS S S      +
Sbjct: 1679 KTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEK 1738

Query: 779  SRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRS 817
            SRS  R RS SS     +  R RS S  P   +RSRSRS
Sbjct: 1739 SRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRS 1777



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 54/174 (31%), Positives = 73/174 (41%), Gaps = 31/174 (17%)

Query: 667 KPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDR--PRNSEGWEQNGLYEFFRAKMRAR 724
           +PL    +   P  PPSE          + P+ DR  P++ E   Q+   E      +  
Sbjct: 379 QPLATTPLSQEPVNPPSE----------ASPTRDRSPPKSPEKLPQSSSSESSPPSPQPT 428

Query: 725 R-RKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRS-- 781
           +  +        P  + +    R  SSS ++   S       +S S + SR   RSRS  
Sbjct: 429 KVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPA 488

Query: 782 ---RSRSRSRS------SRSRSRSQSRSRS-----KSYSPGRRRRSRSRSPTPP 821
              R RSRSR+      SRSRS    RSRS     +S SP  +RR RSRSP  P
Sbjct: 489 TAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSP--QRRGRSRSPQRP 540



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 47/131 (35%), Positives = 67/131 (51%), Gaps = 20/131 (15%)

Query: 720 KMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRS-SKSSGSYSRSRSRS--CSRSY 776
           K ++R  + + + NS P   +SR  SR RS S S+ RS +KS  S  RS S S  C +  
Sbjct: 731 KNKSRTSQRRSRSNSSPEMKKSRISSR-RSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQK 789

Query: 777 SRS---RSRS-----RSRSRSSRSRSRSQSR--SRSKSYSPGRRRRSRS------RSPTP 820
           S++   RSRS     +++SR+   RSRS S    + KS +P R+  S S      +S TP
Sbjct: 790 SQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTP 849

Query: 821 PSSAGLGSNSA 831
           P    + S  A
Sbjct: 850 PRQGSITSPQA 860



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 44/123 (35%), Positives = 59/123 (47%), Gaps = 17/123 (13%)

Query: 726  RKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRS 785
            R+ +   +S  +RSR+  + R RS S S+   ++ S S  R RS S  R+ + SR R RS
Sbjct: 1705 RRSRSASSSPETRSRTPPRHR-RSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR-RGRS 1762

Query: 786  RSRSSRSRSRSQSRSR--------------SKSYSPGRRRRSRSRS-PTPPSSAGLGSNS 830
             S   R   RS+SRSR              S   +  RR+RSRSRS  T     G G +S
Sbjct: 1763 PSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHS 1822

Query: 831  APP 833
              P
Sbjct: 1823 RSP 1825



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 46/149 (30%), Positives = 61/149 (40%), Gaps = 29/149 (19%)

Query: 718  RAKMRARRRKGQE-----KRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSC 772
            R  +R R R G       K    P RSRS S    +   R+  R+   S S    ++ + 
Sbjct: 1570 RTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAP 1629

Query: 773  SRSYSRSRSRSRS---------------------RSRSSRSRSRSQSRSRSKSYSPGRRR 811
                 RSRS S S                     +SR++R  SRS    ++KS +P RRR
Sbjct: 1630 RALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRR 1689

Query: 812  RSRSRSPTPPSSAGLG--SNSAPPIPDSR 838
             SRS SP     A L   S SA   P++R
Sbjct: 1690 SSRS-SPELTRKARLSRRSRSASSSPETR 1717



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 54/155 (34%), Positives = 68/155 (43%), Gaps = 20/155 (12%)

Query: 677  PPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGP 736
            P P  P+ R L       S  S  R  + EG            K R  RR     R+S  
Sbjct: 1622 PEPKAPAPRALPRRSRSGSS-SKGRGPSPEGSSSTESSPEHPPKSRTARRGS---RSSPE 1677

Query: 737  SRSRSRSKSRGRSSSRSN--------SRSSKSSGSYSRSRSRSCSR---SYSRSRSRSRS 785
             +++SR+  R RSS  S         SR S+S+ S   +RSR+  R   S S S      
Sbjct: 1678 PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAE 1737

Query: 786  RSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTP 820
            +SRSSR R RS S  R+K+ S    RR RS SP P
Sbjct: 1738 KSRSSRRR-RSASSPRTKTTS----RRGRSPSPKP 1767



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 46/175 (26%), Positives = 70/175 (40%), Gaps = 25/175 (14%)

Query: 695 SPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKS---RGRSSS 751
           S P  +R ++S+  +     E  + K R+   K + K +    R RSRS +   + R + 
Sbjct: 203 SSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRK-SKDKKRKRSRSTTPAPKSRRAH 261

Query: 752 RSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSR-------SRSQSRSRSKS 804
           RS S  S SS   SRSRSRS +     +    RS S +S  R       S   + S  + 
Sbjct: 262 RSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRP 321

Query: 805 YSP--------------GRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLGEENKG 845
            SP               + ++ +S +   PS     +   PP P   L E + G
Sbjct: 322 SSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGG 376



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 44/147 (29%), Positives = 51/147 (34%), Gaps = 34/147 (23%)

Query: 723  ARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRS--------------- 767
            A  +  +E+R+S  S S S S S   SSS S+S S  SS     S               
Sbjct: 2522 AALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPS 2581

Query: 768  -------------------RSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPG 808
                                 R    S S S S S S S SS S S S S S S S S  
Sbjct: 2582 PTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641

Query: 809  RRRRSRSRSPTPPSSAGLGSNSAPPIP 835
                S S SP  P    L   ++P  P
Sbjct: 2642 SSSSSSSPSPAKPGPQALPKPASPKKP 2668



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 43/129 (33%), Positives = 50/129 (38%), Gaps = 25/129 (19%)

Query: 729  QEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSR-------- 780
            + KR S  S S S S S   SSS S+S SS SS S S S S S S S S ++        
Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661

Query: 781  ---------SRSRSRS--------RSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSS 823
                        RSRS        R SRS S S    R  S  P  R +  S S      
Sbjct: 2662 PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721

Query: 824  AGLGSNSAP 832
               G + +P
Sbjct: 2722 GQRGDSRSP 2730



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 38/116 (32%), Positives = 49/116 (42%), Gaps = 2/116 (1%)

Query: 709  EQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSR 768
            E++G       K  AR   GQ  R SG S+     K       RS S SS  S + +R+ 
Sbjct: 1515 ERSGSESSVDQKTVARTPLGQRSR-SGSSQELD-VKPSASPQERSESDSSPDSKAKTRTP 1572

Query: 769  SRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSA 824
             R  SRS S     S+SR    RSRS S    + K  +  R +     SP P + A
Sbjct: 1573 LRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPA 1628



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 36/99 (36%), Positives = 52/99 (52%), Gaps = 10/99 (10%)

Query: 739  SRSRSKSRGRSSSRSNSRSSKSSGSYSRS-----RSRSCSRSYSRSRSRSRSRSRSSRSR 793
            SRS  + + +S +    RSS+SS   +R      RSRS S S   +RSR+  R R S S 
Sbjct: 1672 SRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSS-PETRSRTPPRHRRSPSV 1730

Query: 794  SRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAP 832
            S  +   +S+S    RRRRS S SP   +++  G + +P
Sbjct: 1731 SSPEPAEKSRS---SRRRRSAS-SPRTKTTSRRGRSPSP 1765



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 46/175 (26%), Positives = 68/175 (38%), Gaps = 17/175 (9%)

Query: 679  PMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRR---KGQEKRNSG 735
            P  PS R  +         S    R+S      G+ +  R   R R       + K    
Sbjct: 1432 PRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQ 1491

Query: 736  PSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRS---------RSR 786
              R RSRS S    +++  +   + SGS S    ++ +R+    RSRS          S 
Sbjct: 1492 TPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSA 1551

Query: 787  SRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLG-----SNSAPPIPD 836
            S   RS S S   S++K+ +P R+R     SP   S + L      S S+P + D
Sbjct: 1552 SPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD 1606



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 46/129 (35%), Positives = 55/129 (42%), Gaps = 19/129 (14%)

Query: 725  RRKGQEKRNSGPSRSRS-RSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRS-- 781
            R K        PSRS S + K +   S R  S S  SS S SR  SR+  R   RSRS  
Sbjct: 898  RVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR---RSRSVS 954

Query: 782  -----RSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSP-------TPPSSAGLGSN 829
                  SR   R S S S S   ++ K  +P R+  S S SP       TPP  +  GS 
Sbjct: 955  PCSNVESRLLPRYSHSGSSSPD-TKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSK 1013

Query: 830  SAPPIPDSR 838
            S  P   S+
Sbjct: 1014 SPCPQEKSK 1022



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 56/195 (28%), Positives = 75/195 (38%), Gaps = 40/195 (20%)

Query: 678 PPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRA---RRRKG----QE 730
           P M  S        +  SP S  + R S     +G     + K +    R R G    + 
Sbjct: 747 PEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKA 806

Query: 731 KRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGS-YSRSRS-------------------- 769
           K  + P RSRS S    +  S++ SR S SS S + + +S                    
Sbjct: 807 KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVT 866

Query: 770 ---RSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGL 826
              RSC  S      +SR+ SR S S S   S  R KS +P R+  SRS SP P   A +
Sbjct: 867 PQRRSCFESSPDPELKSRTPSRHSCSGS---SPPRVKSSTPPRQSPSRSSSPQPKVKAII 923

Query: 827 G------SNSAPPIP 835
                  S S+ P P
Sbjct: 924 SPRQRSHSGSSSPSP 938



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 46/150 (30%), Positives = 52/150 (34%), Gaps = 53/150 (35%)

Query: 722  RARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRS-------------- 767
            R RR       +S  S S S S S   SSS S+S SS SS S S S              
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662

Query: 768  -----------RSRSC-----------SRSYS----------------RSRSRSRSRSRS 789
                       RSRS            S SYS                +S S  R   R 
Sbjct: 2663 ASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRG 2722

Query: 790  SRSRSRSQS-RSRSKSYSPGRRRRSRSRSP 818
             R  SRS S + R ++ SP   R   SRSP
Sbjct: 2723 QRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752



 Score = 33.9 bits (76), Expect = 0.71
 Identities = 53/186 (28%), Positives = 70/186 (37%), Gaps = 47/186 (25%)

Query: 722 RARRRKGQEKRNSG--PSRSRSRSKSRGRSSSRSNSRSSKSSGS-YSRSRS--------- 769
           R+R    Q K  S   P RSRS S    +  S++ SR S SS S + + +S         
Sbjct: 796 RSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSI 855

Query: 770 --------------RSCSRSYSRSRSRSRSRSRSSRSRSRS----------QSRSRSKS- 804
                         RSC  S      +SR+ SR S S S            QS SRS S 
Sbjct: 856 TSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSP 915

Query: 805 -------YSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLGEENKGHQMLVKMGWSGS 857
                   SP +R  S S SP+P   + + S + P    S     N   ++L +   SGS
Sbjct: 916 QPKVKAIISPRQRSHSGSSSPSP---SRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGS 972

Query: 858 GGLGAK 863
                K
Sbjct: 973 SSPDTK 978



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 38/98 (38%), Positives = 48/98 (48%), Gaps = 8/98 (8%)

Query: 737  SRSRSRSKSRG-RSSSRSNSRSSKSSGSYSRS-RSRSCSRSYSRSRSRSRSRSRSSRSRS 794
            SRSR+   +RG RS +RS     + S S S S RSRS +   +R+ S SR+   +  S S
Sbjct: 2054 SRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNS-S 2112

Query: 795  RSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAP 832
            R    SR  S SP    R RS     P    LGS+  P
Sbjct: 2113 RMSCFSR-PSMSPTPLDRCRSPGMLEP----LGSSRTP 2145



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 30/98 (30%), Positives = 43/98 (43%), Gaps = 5/98 (5%)

Query: 743  SKSRGRSSSRSNSRSSKSSG-SYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRS----RSQ 797
            ++S G SSS  +  + + +G S ++S S     +  R+ SR RS S SS        R+ 
Sbjct: 1376 TRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTP 1435

Query: 798  SRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIP 835
            SR      SPG R  S + S    S +  G    P  P
Sbjct: 1436 SRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTP 1473



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 30/90 (33%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 736  PSRSRSRSKSRGRSSS---RSNSRSSKSSGSYS-RSRSRSCSRSYSRSRSRSRSRSRSSR 791
            PSR RS S S         R+ SR S+S  S   R  S + SR      S        + 
Sbjct: 1414 PSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTP 1473

Query: 792  SRSRSQSRSRSKSYSPGRRRRSRSRSPTPP 821
            SR RS+  S  +  +  +  R RSRSP+ P
Sbjct: 1474 SRGRSECDSSPEPKALPQTPRPRSRSPSSP 1503


>gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]
          Length = 1374

 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 90/309 (29%), Positives = 105/309 (33%), Gaps = 63/309 (20%)

Query: 513 PFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFD 572
           PF    PP  +GP PP    P F      H F   PP F     PP  P    P      
Sbjct: 80  PFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFP-VPPCF--PPMPPPMPCPNNPPVPGAP 136

Query: 573 YPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPP 632
             QG FP  M PP       MPHP     PP   PQ  ++  PP             G  
Sbjct: 137 PGQGTFPFMMPPPS------MPHPP----PPPVMPQQVNYQYPP-------------GYS 173

Query: 633 HINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEA 692
           H N   PS      + + P+  +          ++ L P     P P  PSER   + E 
Sbjct: 174 HHNFPPPSFNS---FQNNPSSFLPSANNSSSPHFRHLPP----YPLPKAPSER--RSPER 224

Query: 693 FYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSR 752
                 H    +S G              R  R +  ++R  G S  R R  SR RS   
Sbjct: 225 LKHYDDHRHRDHSHG--------------RGERHRSLDRRERGRSPDRRRQDSRYRSD-- 268

Query: 753 SNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSR-SSRSRSRSQSRSRSKSYSPGRRR 811
                      Y R R+ S  RSY RSR R R R R     RS S  RS  K Y    R 
Sbjct: 269 -----------YDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRS 317

Query: 812 RSRSRSPTP 820
              S  P P
Sbjct: 318 YGLSVVPEP 326



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 71/292 (24%), Positives = 91/292 (31%), Gaps = 63/292 (21%)

Query: 357 PPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPP 416
           P  PP      P   P+T   +S  P  +P   ++        P+A GP  P P    PP
Sbjct: 44  PQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIR--PP 101

Query: 417 NKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGP-PHCPPWNNSHEGMWGEQRGDPGWNGQ 475
                   P PV P     PP  PP P     P P  PP                   GQ
Sbjct: 102 FPNHQMRHPFPVPPC---FPPMPPPMPCPNNPPVPGAPP-------------------GQ 139

Query: 476 RDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQF 535
              P            F  P  S    PP       PP     P      +PP   H  F
Sbjct: 140 GTFP------------FMMPPPSMPHPPP-------PPV---MPQQVNYQYPPGYSHHNF 177

Query: 536 NQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPH---HHPGHR 592
             PP  ++F   P  F+    P  +    P + H   YP    P+E   P    H+  HR
Sbjct: 178 -PPPSFNSFQNNPSSFL----PSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHR 232

Query: 593 MPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPN 644
                  +H    G +H           G+ P  RRQ   + +  D    P+
Sbjct: 233 H-----RDHSHGRGERHRSL---DRRERGRSPDRRRQDSRYRSDYDRGRTPS 276



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 36/111 (32%), Positives = 41/111 (36%), Gaps = 12/111 (10%)

Query: 356 PPPAPPPAPAPAPAIP-----PTTQPDD--SKPPIQMPGSSEYEAPGGVQDPAAAGPRGP 408
           PPP PP A  P P  P     P  Q       PP   P       P     P A   +G 
Sbjct: 82  PPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGT 141

Query: 409 GPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPP-YPHHQGGPPHCPPWNNS 458
            P    PP+ P     P PV P  QQ   + PP Y HH   PP    + N+
Sbjct: 142 FPFMMPPPSMP--HPPPPPVMP--QQVNYQYPPGYSHHNFPPPSFNSFQNN 188



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 28/98 (28%), Positives = 32/98 (32%), Gaps = 9/98 (9%)

Query: 355 PP--PPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAG---PRGPG 409
           PP  PP PPP P P     P   P     P  MP  S    P     P       P G  
Sbjct: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYS 173

Query: 410 PHDQIPPNKPPWFDQPHPVAPWGQQQPPEQ----PPYP 443
            H+  PP+   + + P    P             PPYP
Sbjct: 174 HHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYP 211


>gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]
          Length = 238

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 56/111 (50%), Positives = 66/111 (59%), Gaps = 8/111 (7%)

Query: 731 KRNSGPSRSRSRSKSRGRSSSRSNSRS-SKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRS 789
           +R    SRSRS S+SRGR  SRS SRS  + S S S  RSRS S   SRS S  RSRS S
Sbjct: 124 RRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSASLRRSRSGS 183

Query: 790 SRS----RSRSQSRSRSKSYSPGRRRRSRSRSPTPP---SSAGLGSNSAPP 833
            +     +S S+SRSRS+S S  R  RS+SRSP+P    S +G    SA P
Sbjct: 184 IKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPRRSASP 234



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 58/138 (42%), Positives = 72/138 (52%), Gaps = 7/138 (5%)

Query: 679 PMPPSERLLAAVEA---FYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRR-KGQEKRNS 734
           P  P++R     E     Y    + R R S    ++      R   R+R R +G+  R++
Sbjct: 99  PFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSA 158

Query: 735 GPSRSRSRSKSRGRSSSRSNSRSSKSSGS-YSRSRSRSCSRSYSRSRSR-SRSRSRS-SR 791
            P RSRS S  R RS+S   SRS    GS Y +S SRS SRS S SR R SRS+SRS S 
Sbjct: 159 SPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSPSP 218

Query: 792 SRSRSQSRSRSKSYSPGR 809
            RSRS S S  +S SP R
Sbjct: 219 KRSRSPSGSPRRSASPER 236



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 46/106 (43%), Positives = 52/106 (49%), Gaps = 6/106 (5%)

Query: 736 PSRSR-SRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSR-SR 793
           P RSR  R  +R               G Y+    R   R  SRSRSRS SRSR  R SR
Sbjct: 86  PRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSR 145

Query: 794 SRSQSRS-RSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSR 838
           SRS+SR  RS+S SP   RRSRS S     SA L  + +  I  SR
Sbjct: 146 SRSRSRGRRSRSASP---RRSRSISLRRSRSASLRRSRSGSIKGSR 188



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 35/69 (50%), Positives = 39/69 (56%), Gaps = 5/69 (7%)

Query: 772 CSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSA 831
           C R   R RSRSRSRS S RSR R  SRSRS+S    R RRSRS SP    S  L  + +
Sbjct: 119 CHRYSRRRRSRSRSRSHS-RSRGRRYSRSRSRS----RGRRSRSASPRRSRSISLRRSRS 173

Query: 832 PPIPDSRLG 840
             +  SR G
Sbjct: 174 ASLRRSRSG 182


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 50/146 (34%), Positives = 76/146 (52%), Gaps = 2/146 (1%)

Query: 701 RPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKS 760
           R   S  W +N   E   +  R+  ++   + +S P +   RS+S   +  R +SRS   
Sbjct: 348 RRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSP 407

Query: 761 SGSYSRSRSRSCSRSYSRSRSRSRSRSRS-SRSRSRSQSRSRSKSYSPGRRR-RSRSRSP 818
           + +  RSRSRS  ++  RSRSRS +++R  SRSRS  ++R RS+S SP + R  SRSRSP
Sbjct: 408 NKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSP 467

Query: 819 TPPSSAGLGSNSAPPIPDSRLGEENK 844
                     + +     S+LG  +K
Sbjct: 468 NKARDRSRSRSPSKERDHSQLGSPSK 493



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 51/141 (36%), Positives = 74/141 (52%), Gaps = 27/141 (19%)

Query: 698 SHDRPRNSEGWEQNGLYEFFRAKMRARRRKG----------QEKRNSGPSRSRSRSKSRG 747
           +H R R S  W++N       ++ R+R RKG              + G S+++SR+  RG
Sbjct: 298 THSRVR-SHSWKRN------HSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRG 350

Query: 748 RSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRS---------SRSRSRSQS 798
           RS + S + S + S S+SRS S+      S S  +   RS+S         SRSRS +++
Sbjct: 351 RSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKA 410

Query: 799 RSRSKSYSPGRRR-RSRSRSP 818
           R RS+S SP + R RSRSRSP
Sbjct: 411 RDRSRSRSPYKARDRSRSRSP 431



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 40/104 (38%), Positives = 59/104 (56%), Gaps = 2/104 (1%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYS 777
           R++ R+  +     R+  P+++R RS+SR  S  R +S+    S      RSRS S+   
Sbjct: 449 RSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQ 508

Query: 778 RSRSRSRSRSRS-SRSRSRSQSRSRSKSYSPGRRR-RSRSRSPT 819
             +SRS S+ R   RSRS S+ R R +S SP + R RS+SRSP+
Sbjct: 509 CRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPS 552



 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 44/122 (36%), Positives = 62/122 (50%), Gaps = 20/122 (16%)

Query: 717 FRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSR---------- 766
           ++A+ R+R R   + R+   SRS ++++ R RS S S  R     GS S+          
Sbjct: 444 YKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSP 503

Query: 767 --------SRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSR-SRS 817
                   SRS S  R + RSRS S+ R R  +SRS ++ R RS+S SP   R  R SRS
Sbjct: 504 SKERQCRQSRSSSKERDHRRSRSPSKERQR-RQSRSPNKERDRSQSRSPSEEREHRQSRS 562

Query: 818 PT 819
           P+
Sbjct: 563 PS 564



 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 47/134 (35%), Positives = 66/134 (49%), Gaps = 8/134 (5%)

Query: 718 RAKMRARRRKGQEKRN----SGPSRSRSRSKSRGRSSSRS--NSRSSKSSGSYSRSRSRS 771
           +A+ R+R R   ++R+      PS+ R   +SR  S  R    SRSS     + RSRS S
Sbjct: 469 KARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPS 528

Query: 772 CSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRR-RSRSRSPTPPSSAGLGSNS 830
             R   +SRS ++ R R S+SRS S+ R   +S SP + R R R RSP+         +S
Sbjct: 529 KERQRRQSRSPNKERDR-SQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSS 587

Query: 831 APPIPDSRLGEENK 844
           +     SR    NK
Sbjct: 588 SEERDHSRSRSPNK 601



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 48/139 (34%), Positives = 68/139 (48%), Gaps = 25/139 (17%)

Query: 696 PPSHDR---PRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSR---------- 742
           P SH +   PR S    Q         +  +R R    KRN   +RSR+R          
Sbjct: 278 PQSHSQSRSPRRSRSGSQK--------RTHSRVRSHSWKRNHSRARSRTRKGILSQMGRH 329

Query: 743 --SKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRS 800
             S+S  +  S++ SR+ +   S++ SR+ S  RS+S SRS S+ R     S  R +S  
Sbjct: 330 SQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKES-G 388

Query: 801 RSKSYSPGRRR-RSRSRSP 818
           RS+S SP ++R  SRSRSP
Sbjct: 389 RSQSGSPNKQRDHSRSRSP 407



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 40/106 (37%), Positives = 56/106 (52%), Gaps = 2/106 (1%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYS 777
           R++  ++ R+ ++ R+S   R   RS+S  +   R  SRS       S+SRS S  R + 
Sbjct: 499 RSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHR 558

Query: 778 RSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRR-RSRSRSPTPPS 822
           +SRS S+ R R  R RS S+ R R +S S    R  SRSRSP   S
Sbjct: 559 QSRSPSKERDRR-RWRSPSKERERRQSRSSSEERDHSRSRSPNKQS 603



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 49/145 (33%), Positives = 71/145 (48%), Gaps = 12/145 (8%)

Query: 697 PSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSR 756
           PS +R R  +    N   +  +++  +  R+ ++ R+    R R R +S  +   R  SR
Sbjct: 527 PSKERQRR-QSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSR 585

Query: 757 SSKSSGSYSRSRSRSCSRSYSRSRSRSR----SRSRS-SRSRSRSQSRSRSKSYSPGRRR 811
           SS     +SRSRS +    YSR R+ S+    SRSR+ S+  + SQSR+ SK   P +  
Sbjct: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST 645

Query: 812 RSRS----RSPTPPSSAGLGSNSAP 832
             RS    RSPT  SS  L  N  P
Sbjct: 646 VPRSPDWKRSPTRTSS--LSQNRTP 668



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 43/116 (37%), Positives = 61/116 (52%), Gaps = 14/116 (12%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSR--SRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRS 775
           R++ R+  +     R+  P+++R  SRS+S  ++  RS SRS   +  +SRSRS + +R 
Sbjct: 413 RSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARD 472

Query: 776 YSRSRSRSRSRSRS---SRSRSRSQSRSRSKS---------YSPGRRRRSRSRSPT 819
            SRSRS S+ R  S   S S+ R   RSRS S          S   R   RSRSP+
Sbjct: 473 RSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPS 528



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 37/110 (33%), Positives = 57/110 (51%), Gaps = 4/110 (3%)

Query: 724 RRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRS 783
           R R G +KR     RS S  ++  R+ SR+        G +S+SRS S  +S ++SR+  
Sbjct: 289 RSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPR 348

Query: 784 RSRSRS-SRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAP 832
           R RS + SR+ S+ +S S S+S S  R  R    S +P   +G   + +P
Sbjct: 349 RGRSHNWSRNPSKERSHSHSRSSSKERDHRG---SSSPRKESGRSQSGSP 395



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 43/109 (39%), Positives = 57/109 (52%), Gaps = 8/109 (7%)

Query: 719 AKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNS--RSSKSSGSYSRSRSRSCSRSY 776
           +K R  RR     +     +SRS +K R RS SRS S  R  + S S S+ R R   RS 
Sbjct: 516 SKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSP 575

Query: 777 SRSRSRSRSRSRSS-RSRSRSQSRSRSKSYSPGR-----RRRSRSRSPT 819
           S+ R R +SRS S  R  SRS+S ++   YS  R     +  SRSR+P+
Sbjct: 576 SKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPS 624



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 46/151 (30%), Positives = 69/151 (45%), Gaps = 10/151 (6%)

Query: 695 SPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGR----SS 750
           SP    + R S    +   +   R+  + R+R+     N    RS+SRS S  R    S 
Sbjct: 502 SPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSR 561

Query: 751 SRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRS-----SRSRSRSQSRSRSKSY 805
           S S  R  +   S S+ R R  SRS S  R  SRSRS +     SR R+ S+ ++ S+S 
Sbjct: 562 SPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSR 621

Query: 806 SPGRRRRSRSRSPTPPSSAGLGSNSAPPIPD 836
           +P  +  + S+S T    +    ++ P  PD
Sbjct: 622 TPS-KEGNHSQSRTSSKESDPSQSTVPRSPD 651



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 41/135 (30%), Positives = 69/135 (51%), Gaps = 12/135 (8%)

Query: 697 PSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSR 756
           PS ++  N        +  + +  + +R +       S   +S +++ +R R  S S SR
Sbjct: 226 PSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSR 285

Query: 757 SSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRS-----------SRSRSRSQSRSRSKSY 805
           S + S S S+ R+ S  RS+S  R+ SR+RSR+           S+SRS S+ +S+++S 
Sbjct: 286 SPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSR 345

Query: 806 SPGRRRRSRSRSPTP 820
           +P RR RS + S  P
Sbjct: 346 TP-RRGRSHNWSRNP 359



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 44/126 (34%), Positives = 58/126 (46%), Gaps = 6/126 (4%)

Query: 726 RKGQEKRNSGPSRSR----SRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRS 781
           ++   +R+  PS+ R    SRS S+ R   RS S S +     SRS ++   RS SRS S
Sbjct: 493 KERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPS 552

Query: 782 RSRSRSRSSRSRSRSQSRSRSKSYSPGR-RRRSRSRSPTPPSSAGLGSNSAPPIPDSRLG 840
             R   R SRS S+ + R R +S S  R RR+SRS S     S     N        R  
Sbjct: 553 EEREH-RQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRAS 611

Query: 841 EENKGH 846
            + K H
Sbjct: 612 SKEKAH 617



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 36/113 (31%), Positives = 61/113 (53%), Gaps = 5/113 (4%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYS 777
           R +  ++ R+ ++ R+S   R  SRS+S  + S  S  R+S    ++SRSR+ S   ++S
Sbjct: 571 RWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHS 630

Query: 778 RSRSRSR----SRSRSSRSRSRSQSRSRSKSYSPGRR-RRSRSRSPTPPSSAG 825
           +SR+ S+    S+S   RS    +S +R+ S S  R   ++ S SP+   S G
Sbjct: 631 QSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGG 683



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 31/124 (25%), Positives = 54/124 (43%), Gaps = 11/124 (8%)

Query: 718 RAKMRARRRKGQEKRNSGPSRS-----------RSRSKSRGRSSSRSNSRSSKSSGSYSR 766
           R+K R   R   + R S  S++            SR ++ GR  SRS+ RS   + +  R
Sbjct: 85  RSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGR 144

Query: 767 SRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGL 826
            R+       +       S+ + SR +S  + R+ ++  S  + R    +S  PP  +G+
Sbjct: 145 IRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGI 204

Query: 827 GSNS 830
           G +S
Sbjct: 205 GRSS 208



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 8/107 (7%)

Query: 741 SRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSR- 799
           SR+     SSS+S   +S      +R  SRS  RS +R+ SR  + +R+S++   S  R 
Sbjct: 52  SRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRC 111

Query: 800 -----SRSKSYSPGRR-RRSRSRSPTPPSSAG-LGSNSAPPIPDSRL 839
                + S+  +PGRR  RS  RSP+  S+ G + ++ A P   SR+
Sbjct: 112 HQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRV 158



 Score = 30.4 bits (67), Expect = 7.9
 Identities = 37/132 (28%), Positives = 56/132 (42%), Gaps = 30/132 (22%)

Query: 731 KRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYS-----------RSRSRSCSRSYSRS 779
           KR+S PS S + S S   ++      S KS+ S +            SR+   S S S+S
Sbjct: 5   KRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKS 64

Query: 780 -RSRSRSRSRSSRSRSRSQSRSRSKSYSP------------------GRRRRSRSRSPTP 820
            +S S  R+ S+R  SRS+ RS++++ S                    +RR + SR  TP
Sbjct: 65  TKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTP 124

Query: 821 PSSAGLGSNSAP 832
                  S  +P
Sbjct: 125 GRRGSRSSKRSP 136


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 54/124 (43%), Positives = 65/124 (52%), Gaps = 2/124 (1%)

Query: 724 RRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRS 783
           R  +   KR++   RS SRS+SR  S  RS     + S S  R R R  SRS  + RSRS
Sbjct: 3   RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62

Query: 784 RSRSRSSRSRSRSQSRSRSKSYSPGR-RRRSRSRSPTPPS-SAGLGSNSAPPIPDSRLGE 841
           R R R  RSRSR + RSR +  S  R RRRSRSRS    S S+  G+ S      SR  E
Sbjct: 63  RDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122

Query: 842 ENKG 845
           +  G
Sbjct: 123 KTDG 126



 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 47/102 (46%), Positives = 56/102 (54%), Gaps = 2/102 (1%)

Query: 717 FRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSY 776
           +R +  +R R G   R+  PS  RS+     RS SR   R  + S S  + RSRS  R  
Sbjct: 8   YRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKR 67

Query: 777 SRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSP 818
            R RSRSR R RS R R RS+SR R +S S  R RRSRS SP
Sbjct: 68  LR-RSRSRERDRS-RERRRSRSRDRRRSRSRSRGRRSRSSSP 107



 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 56/134 (41%), Positives = 68/134 (50%), Gaps = 11/134 (8%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSR-SRSCSRSY 776
           R+  R+R R   +KR+      RSRS+ R R   RS SR  + S S  R R  RS SR  
Sbjct: 17  RSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRER 76

Query: 777 SRSRSRSRSRSRS-SRSRSRSQSRSRSKSYSPGRR-----RRSRSRSPTPPSSAGLGSNS 830
            RSR R RSRSR   RSRSRS+ R RS+S SPG +      RSRS+  T     G  S  
Sbjct: 77  DRSRERRRSRSRDRRRSRSRSRGR-RSRSSSPGNKSKKTENRSRSKEKT---DGGESSKE 132

Query: 831 APPIPDSRLGEENK 844
                D +  E+ K
Sbjct: 133 KKKDKDDKEDEKEK 146



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 66/188 (35%), Positives = 81/188 (43%), Gaps = 41/188 (21%)

Query: 747 GRSSSRSNSRSSKSSGSYSRSRSRSCS----------RSYSRSRSRSRSRSRS-----SR 791
           GR S     RS+    S SRSRSRS S          RS SR R R R RSRS     SR
Sbjct: 2   GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61

Query: 792 SRSRS---QSRSRSKSYSPGRRR-RSRSRSPTPPSSAGLGSNSAPPIPDSRLGEENKGHQ 847
           SR R    +SRSR +  S  RRR RSR R  +   S G  S S+ P      G ++K  +
Sbjct: 62  SRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSP------GNKSKKTE 115

Query: 848 MLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQ-YKGVGVALDDPYENYRRNKSYSFI 906
              +      GG  +KE       K  D  DK D+  K  G        N+ +NK    +
Sbjct: 116 NRSRSKEKTDGGESSKE-------KKKDKDDKEDEKEKDAG--------NFDQNKLEEEM 160

Query: 907 ARMKARDE 914
            + K R E
Sbjct: 161 RKRKERVE 168



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 2/98 (2%)

Query: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYS 777
           R++ R R R  + +R+    R RSRS+SRGR S RS+S  +KS  + +RSRS+  +    
Sbjct: 70  RSRSRERDRSRERRRSRSRDRRRSRSRSRGRRS-RSSSPGNKSKKTENRSRSKEKTDGGE 128

Query: 778 RSRSRSRSRSRSSRSRSRSQSR-SRSKSYSPGRRRRSR 814
            S+ + + +      + +      ++K     R+R+ R
Sbjct: 129 SSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKER 166


>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
           sapiens]
          Length = 482

 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 54/127 (42%), Positives = 68/127 (53%), Gaps = 14/127 (11%)

Query: 703 RNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSG 762
           +NSE  E+ G ++ + +++R RR       N  P  S  R+    R SSR   + S    
Sbjct: 359 KNSERRERMGHHDDYYSRLRGRR-------NPSPDHSYKRNGESERKSSRHRGKKSHKRT 411

Query: 763 SYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQS----RSRSKSYSPGR---RRRSRS 815
           S SR R  S SR  +R RSR RSR R SRSRSRS+S    RSRS+S S  R   RRRS +
Sbjct: 412 SKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGN 471

Query: 816 RSPTPPS 822
           R  T  S
Sbjct: 472 RDRTVQS 478



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 45/106 (42%), Positives = 55/106 (51%), Gaps = 15/106 (14%)

Query: 697 PSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSR 756
           P H   RN E   ++  +     K   R  K +E+ NS     RSR ++R RS  RS  R
Sbjct: 385 PDHSYKRNGESERKSSRHR--GKKSHKRTSKSRERHNS-----RSRGRNRDRSRDRSRGR 437

Query: 757 SSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRS 802
                   SRSRSRS SR   RSRS+S SRSR SR R RS +R R+
Sbjct: 438 G-------SRSRSRSRSRRSRRSRSQSSSRSR-SRGRRRSGNRDRT 475



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 42/131 (32%), Positives = 58/131 (44%), Gaps = 4/131 (3%)

Query: 701 RPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKS 760
           R  N+E WE N        +  +   K  E+R          S+ RGR +  S   S K 
Sbjct: 333 RNPNNEFWEANRDIYLSPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNP-SPDHSYKR 391

Query: 761 SGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTP 820
           +G   R  SR   +   +  S+SR R  S   RSR ++R RS+  S GR  RSRSRS + 
Sbjct: 392 NGESERKSSRHRGKKSHKRTSKSRERHNS---RSRGRNRDRSRDRSRGRGSRSRSRSRSR 448

Query: 821 PSSAGLGSNSA 831
            S      +S+
Sbjct: 449 RSRRSRSQSSS 459


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 90/309 (29%), Positives = 107/309 (34%), Gaps = 75/309 (24%)

Query: 329 AQQQQQQQQQQQQLQMPQMEAEVK-------------ATPPPPAPPPAPAPAPAIPPTTQ 375
           AQQQQ  QQ ++    P    +VK             A PPPP  P      P +PP   
Sbjct: 311 AQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHP 370

Query: 376 PDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQ 435
           P D KPP+      E E PG V            P  QIPP          P  P    Q
Sbjct: 371 PPDRKPPL-AAALGEAEPPGPVDATDL-------PKVQIPP----------PAHPAPVHQ 412

Query: 436 PPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNNQPDAAWNSQFEGP 495
           P   PP PH    PP  PP       M G        +G+      +        + EGP
Sbjct: 413 P---PPLPHR---PPPPPP----SSYMTGMSTTSSYMSGEGYQSLQSM------MKTEGP 456

Query: 496 WNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDD 555
             S    PP  G    PP  +   PH   P PP         PP P     FPP  +   
Sbjct: 457 --SYGALPPAYG----PPAHLPYHPHVYPPNPP--------PPPVPPPPASFPPPAIP-- 500

Query: 556 FPPRHPFERPPYPHRFDYPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPP 615
            PP   +  PP  +  ++P    P  + P H  P    PHP     PP  G     + PP
Sbjct: 501 -PPTPGYPPPPPTYNPNFPPP--PPRLPPTHAVP----PHP-----PPGLGLPPASYPPP 548

Query: 616 PHGFNGQPP 624
                GQPP
Sbjct: 549 AVPPGGQPP 557



 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 86/344 (25%), Positives = 115/344 (33%), Gaps = 63/344 (18%)

Query: 354 TPPPPAPPPAPAPAPAIPPT--TQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPH 411
           TP     PP+  P P +P    +QP  S  P Q P   + + P   Q PA   P+ P P 
Sbjct: 269 TPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQ-PQQKDPQQPAQQQQPAQQ-PKKPSPQ 326

Query: 412 DQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPG 471
               P+ P    +   V+P  + +  E PP        P  P    +H          P 
Sbjct: 327 ----PSSPRQVKRAVVVSPKEENKAAEPPP--------PKIPKIETTH----------PP 364

Query: 472 WNGQRDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQ 531
                  P    P AA   + E P        P          ++Q PP    P P HQ 
Sbjct: 365 LPPAHPPPDRKPPLAAALGEAEPPGPVDATDLP----------KVQIPPPAH-PAPVHQP 413

Query: 532 HPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQ-GDFPAEMGPPHHHPG 590
            P  ++PP P   +          +     ++      + + P  G  P   GPP H P 
Sbjct: 414 PPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPY 473

Query: 591 HR-----------MPHPGINEHPPWAGPQHPDFGPPPHGFNGQ-PPHMRRQGPPHINHDD 638
           H            +P P  +  PP   P  P + PPP  +N   PP   R  P H     
Sbjct: 474 HPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTH----- 528

Query: 639 PSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPP 682
              VP  P    P GL  P          P     +  PPP+PP
Sbjct: 529 --AVPPHP----PPGLGLPPASYPPPAVPPGGQPPV--PPPIPP 564



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 41/109 (37%), Positives = 43/109 (39%), Gaps = 14/109 (12%)

Query: 355 PPPPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQI 414
           PPP  PPPA  P PAIPP T      PP   P    +  P     P  A P  P P   +
Sbjct: 484 PPPVPPPPASFPPPAIPPPTPGYPPPPPTYNP---NFPPPPPRLPPTHAVPPHPPPGLGL 540

Query: 415 PPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMW 463
           PP   P    P  V P G  QPP  PP P     PP  PP        W
Sbjct: 541 PPASYP----PPAVPPGG--QPPVPPPIP-----PPGMPPVGGLGRAAW 578


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,484,894
Number of Sequences: 37866
Number of extensions: 3582234
Number of successful extensions: 69566
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 951
Number of HSP's successfully gapped in prelim test: 1645
Number of HSP's that attempted gapping in prelim test: 22533
Number of HSP's gapped (non-prelim): 23601
length of query: 916
length of database: 18,247,518
effective HSP length: 111
effective length of query: 805
effective length of database: 14,044,392
effective search space: 11305735560
effective search space used: 11305735560
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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