Guide to the Human Genome
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Search of human proteins with 239754359

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239754359 PREDICTED: similar to heat shock 70kD protein
binding protein [Homo sapiens]
         (204 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239754359 PREDICTED: similar to heat shock 70kD protein bindi...   405   e-113
gi|239748906 PREDICTED: hypothetical protein XP_002346852 [Homo ...   405   e-113
gi|239742930 PREDICTED: hypothetical protein XP_002342689 [Homo ...   403   e-113
gi|19923193 heat shock 70kD protein binding protein [Homo sapiens]    201   3e-52
gi|130977759 tec protein tyrosine kinase [Homo sapiens]                90   2e-18
gi|4502435 BMX non-receptor tyrosine kinase [Homo sapiens]             63   2e-10
gi|42544182 BMX non-receptor tyrosine kinase [Homo sapiens]            63   2e-10
gi|4557377 Bruton agammaglobulinemia tyrosine kinase [Homo sapiens]    59   4e-09
gi|15718680 IL2-inducible T-cell kinase [Homo sapiens]                 57   1e-08
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H...    40   0.002
gi|38201692 RAS p21 protein activator 3 [Homo sapiens]                 39   0.002
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    38   0.007
gi|215422388 death-domain associated protein isoform a [Homo sap...    38   0.007
gi|215422366 death-domain associated protein isoform b [Homo sap...    38   0.007
gi|55956788 nucleolin [Homo sapiens]                                   37   0.009
gi|116256485 chromosome 6 open reading frame 10 [Homo sapiens]         37   0.012
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              36   0.020
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    36   0.026
gi|82830424 gon-4-like isoform a [Homo sapiens]                        35   0.034
gi|5729790 CCCTC-binding factor [Homo sapiens]                         35   0.044
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap...    35   0.044
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap...    35   0.044
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi...    35   0.044
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    35   0.044
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H...    34   0.075
gi|21361639 DIPB protein [Homo sapiens]                                34   0.075
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]     34   0.075
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]     34   0.075
gi|7657441 PDGFA associated protein 1 [Homo sapiens]                   34   0.098
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...    34   0.098

>gi|239754359 PREDICTED: similar to heat shock 70kD protein binding
           protein [Homo sapiens]
          Length = 204

 Score =  405 bits (1040), Expect = e-113
 Identities = 204/204 (100%), Positives = 204/204 (100%)

Query: 1   MDTRKVNELRAFVKMCKQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP 60
           MDTRKVNELRAFVKMCKQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP
Sbjct: 1   MDTRKVNELRAFVKMCKQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP 60

Query: 61  DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDGRKAPDSTVQTAPRSLPRS 120
           DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDGRKAPDSTVQTAPRSLPRS
Sbjct: 61  DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDGRKAPDSTVQTAPRSLPRS 120

Query: 121 AQQPRFSQNTGIFSGRRSNQKMEMNFNIILEEILIKRSQQKKKTSPLNYKERLFVLTKPM 180
           AQQPRFSQNTGIFSGRRSNQKMEMNFNIILEEILIKRSQQKKKTSPLNYKERLFVLTKPM
Sbjct: 121 AQQPRFSQNTGIFSGRRSNQKMEMNFNIILEEILIKRSQQKKKTSPLNYKERLFVLTKPM 180

Query: 181 LTYYEGRAEQFLVISKSLVLKMAE 204
           LTYYEGRAEQFLVISKSLVLKMAE
Sbjct: 181 LTYYEGRAEQFLVISKSLVLKMAE 204


>gi|239748906 PREDICTED: hypothetical protein XP_002346852 [Homo
           sapiens]
          Length = 204

 Score =  405 bits (1040), Expect = e-113
 Identities = 204/204 (100%), Positives = 204/204 (100%)

Query: 1   MDTRKVNELRAFVKMCKQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP 60
           MDTRKVNELRAFVKMCKQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP
Sbjct: 1   MDTRKVNELRAFVKMCKQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP 60

Query: 61  DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDGRKAPDSTVQTAPRSLPRS 120
           DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDGRKAPDSTVQTAPRSLPRS
Sbjct: 61  DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDGRKAPDSTVQTAPRSLPRS 120

Query: 121 AQQPRFSQNTGIFSGRRSNQKMEMNFNIILEEILIKRSQQKKKTSPLNYKERLFVLTKPM 180
           AQQPRFSQNTGIFSGRRSNQKMEMNFNIILEEILIKRSQQKKKTSPLNYKERLFVLTKPM
Sbjct: 121 AQQPRFSQNTGIFSGRRSNQKMEMNFNIILEEILIKRSQQKKKTSPLNYKERLFVLTKPM 180

Query: 181 LTYYEGRAEQFLVISKSLVLKMAE 204
           LTYYEGRAEQFLVISKSLVLKMAE
Sbjct: 181 LTYYEGRAEQFLVISKSLVLKMAE 204


>gi|239742930 PREDICTED: hypothetical protein XP_002342689 [Homo
           sapiens]
          Length = 204

 Score =  403 bits (1035), Expect = e-113
 Identities = 203/204 (99%), Positives = 203/204 (99%)

Query: 1   MDTRKVNELRAFVKMCKQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP 60
           MD RKVNELRAFVKMCKQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP
Sbjct: 1   MDARKVNELRAFVKMCKQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP 60

Query: 61  DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDGRKAPDSTVQTAPRSLPRS 120
           DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDGRKAPDSTVQTAPRSLPRS
Sbjct: 61  DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDGRKAPDSTVQTAPRSLPRS 120

Query: 121 AQQPRFSQNTGIFSGRRSNQKMEMNFNIILEEILIKRSQQKKKTSPLNYKERLFVLTKPM 180
           AQQPRFSQNTGIFSGRRSNQKMEMNFNIILEEILIKRSQQKKKTSPLNYKERLFVLTKPM
Sbjct: 121 AQQPRFSQNTGIFSGRRSNQKMEMNFNIILEEILIKRSQQKKKTSPLNYKERLFVLTKPM 180

Query: 181 LTYYEGRAEQFLVISKSLVLKMAE 204
           LTYYEGRAEQFLVISKSLVLKMAE
Sbjct: 181 LTYYEGRAEQFLVISKSLVLKMAE 204


>gi|19923193 heat shock 70kD protein binding protein [Homo sapiens]
          Length = 369

 Score =  201 bits (512), Expect = 3e-52
 Identities = 98/101 (97%), Positives = 99/101 (98%)

Query: 1   MDTRKVNELRAFVKMCKQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP 60
           MD RKVNELRAFVKMCKQDPS+LHTEEM FLREWVESMGGKVPPATQKAKSEENTKEEKP
Sbjct: 1   MDPRKVNELRAFVKMCKQDPSVLHTEEMRFLREWVESMGGKVPPATQKAKSEENTKEEKP 60

Query: 61  DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGD 101
           DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGD
Sbjct: 61  DSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGD 101


>gi|130977759 tec protein tyrosine kinase [Homo sapiens]
          Length = 631

 Score = 89.7 bits (221), Expect = 2e-18
 Identities = 47/58 (81%), Positives = 50/58 (86%), Gaps = 5/58 (8%)

Query: 144 MNFNIILEEILIKRSQQKKKTSPLNYKERLFVLTKPMLTYYEGRAEQ-----FLVISK 196
           MNFN ILEEILIKRSQQKKKTSPLNYKERLFVLTK MLTYYEGRAE+     F+ +SK
Sbjct: 1   MNFNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSMLTYYEGRAEKKYRKGFIDVSK 58


>gi|4502435 BMX non-receptor tyrosine kinase [Homo sapiens]
          Length = 675

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 31/42 (73%), Positives = 35/42 (83%)

Query: 144 MNFNIILEEILIKRSQQKKKTSPLNYKERLFVLTKPMLTYYE 185
           M+   ILEE+L+KRSQQKKK SP NYKERLFVLTK  L+YYE
Sbjct: 1   MDTKSILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYE 42


>gi|42544182 BMX non-receptor tyrosine kinase [Homo sapiens]
          Length = 675

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 31/42 (73%), Positives = 35/42 (83%)

Query: 144 MNFNIILEEILIKRSQQKKKTSPLNYKERLFVLTKPMLTYYE 185
           M+   ILEE+L+KRSQQKKK SP NYKERLFVLTK  L+YYE
Sbjct: 1   MDTKSILEELLLKRSQQKKKMSPNNYKERLFVLTKTNLSYYE 42


>gi|4557377 Bruton agammaglobulinemia tyrosine kinase [Homo sapiens]
          Length = 659

 Score = 58.5 bits (140), Expect = 4e-09
 Identities = 27/38 (71%), Positives = 33/38 (86%)

Query: 148 IILEEILIKRSQQKKKTSPLNYKERLFVLTKPMLTYYE 185
           +ILE I +KRSQQKKKTSPLN+K+RLF+LT   L+YYE
Sbjct: 4   VILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYE 41


>gi|15718680 IL2-inducible T-cell kinase [Homo sapiens]
          Length = 620

 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 28/44 (63%), Positives = 34/44 (77%)

Query: 144 MNFNIILEEILIKRSQQKKKTSPLNYKERLFVLTKPMLTYYEGR 187
           MN  I+LEE LIK+SQQK++TSP N+K R FVLTK  L Y+E R
Sbjct: 1   MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDR 44


>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
           sapiens]
          Length = 1094

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 1/99 (1%)

Query: 19  DPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSE- 77
           DPS+ + E +   +EW  +   K   + +K  SE   +E+  DS    E     E   + 
Sbjct: 645 DPSVRNVEVIELAKEWTPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQG 704

Query: 78  ESDLEIDKEGVIEPDTDAPQEMGDGRKAPDSTVQTAPRS 116
           ES  E D       D+ + Q+   GR++     +TA R+
Sbjct: 705 ESGEEGDSNEDSSEDSSSEQDSESGRESGLENKRTAKRN 743



 Score = 28.5 bits (62), Expect = 4.1
 Identities = 16/54 (29%), Positives = 26/54 (48%), Gaps = 4/54 (7%)

Query: 46  TQKAKSEENTKEEKPDSKKVEEDLKADEPSSEES----DLEIDKEGVIEPDTDA 95
           T K  S+   K +  D +K  E  K  + S++ES    D   D E   EP++++
Sbjct: 739 TAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESESEPESES 792


>gi|38201692 RAS p21 protein activator 3 [Homo sapiens]
          Length = 834

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 20/57 (35%), Positives = 34/57 (59%), Gaps = 1/57 (1%)

Query: 134 SGRRSNQKMEMNFNIILEEILIKRSQQKKKTSPLNYKERLFVLTKPMLTYYEGRAEQ 190
           SGRR  + +E    ++ E  +IKR+Q +K+    N+K+R F LT    TY++ + +Q
Sbjct: 564 SGRRDPKSVEQPI-VLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYHKSKGDQ 619


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 33/132 (25%), Positives = 63/132 (47%), Gaps = 12/132 (9%)

Query: 33  EWVESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEP--SSEESDLEIDKEGVIE 90
           E    M  +  P+  +A++++   EE  + ++ EE+ + +E   S EE DLE  +EG  +
Sbjct: 417 EGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQED 476

Query: 91  PDTDAPQEMG----DGRKAPDSTVQTAPRSLPRSAQQPRFSQNTGIFSGRRSNQKMEMNF 146
            + +  +E      DG K+P S++Q +        +Q   S      SG + N+   ++ 
Sbjct: 477 DEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRS------SGEQQNKGRIVSP 530

Query: 147 NIILEEILIKRS 158
           +++ EE L   S
Sbjct: 531 SLLSEEPLAPSS 542


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 33/132 (25%), Positives = 63/132 (47%), Gaps = 12/132 (9%)

Query: 33  EWVESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEP--SSEESDLEIDKEGVIE 90
           E    M  +  P+  +A++++   EE  + ++ EE+ + +E   S EE DLE  +EG  +
Sbjct: 417 EGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQED 476

Query: 91  PDTDAPQEMG----DGRKAPDSTVQTAPRSLPRSAQQPRFSQNTGIFSGRRSNQKMEMNF 146
            + +  +E      DG K+P S++Q +        +Q   S      SG + N+   ++ 
Sbjct: 477 DEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRS------SGEQQNKGRIVSP 530

Query: 147 NIILEEILIKRS 158
           +++ EE L   S
Sbjct: 531 SLLSEEPLAPSS 542


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 33/132 (25%), Positives = 63/132 (47%), Gaps = 12/132 (9%)

Query: 33  EWVESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEP--SSEESDLEIDKEGVIE 90
           E    M  +  P+  +A++++   EE  + ++ EE+ + +E   S EE DLE  +EG  +
Sbjct: 429 EGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQED 488

Query: 91  PDTDAPQEMG----DGRKAPDSTVQTAPRSLPRSAQQPRFSQNTGIFSGRRSNQKMEMNF 146
            + +  +E      DG K+P S++Q +        +Q   S      SG + N+   ++ 
Sbjct: 489 DEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRS------SGEQQNKGRIVSP 542

Query: 147 NIILEEILIKRS 158
           +++ EE L   S
Sbjct: 543 SLLSEEPLAPSS 554


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 37.4 bits (85), Expect = 0.009
 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 41  KVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAP---- 96
           KV P   K  +E+  +EE  D  + ++D + DE   +E D E ++E   EP  +AP    
Sbjct: 223 KVVPVKAKNVAEDEDEEED-DEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRK 281

Query: 97  QEMGDGRKAPDSTVQTAPRSLPRSA 121
           +EM   + AP++  Q    + P +A
Sbjct: 282 KEMAKQKAAPEAKKQKVEGTEPTTA 306



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 6/51 (11%)

Query: 50  KSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMG 100
           K++ + K+  P  K+VEED + +E S +E D    +E VI      PQ+ G
Sbjct: 9   KNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVI------PQKKG 53



 Score = 28.9 bits (63), Expect = 3.2
 Identities = 19/83 (22%), Positives = 36/83 (43%), Gaps = 6/83 (7%)

Query: 47  QKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEP------DTDAPQEMG 100
           + AK E++ +EE  DS++ EED + ++   +E +    K     P      D D   +  
Sbjct: 138 KNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDED 197

Query: 101 DGRKAPDSTVQTAPRSLPRSAQQ 123
           D     D + + A  + P   ++
Sbjct: 198 DDDDEEDDSEEEAMETTPAKGKK 220


>gi|116256485 chromosome 6 open reading frame 10 [Homo sapiens]
          Length = 563

 Score = 37.0 bits (84), Expect = 0.012
 Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 11/108 (10%)

Query: 47  QKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDK--EGVIEP-DTDAPQEM---- 99
           +K++S  +  +E    K+    LK  E   E+S+L++ K  EG +E  + D P+E     
Sbjct: 384 KKSQSGVSKGQEAQVKKRESVVLKGQEAQVEKSELKVPKGQEGQVEKTEADVPKEQEVQE 443

Query: 100 ----GDGRKAPDSTVQTAPRSLPRSAQQPRFSQNTGIFSGRRSNQKME 143
                   K P+S V+    S+P + +       +G+  G+ + +K E
Sbjct: 444 KKSEAGVLKGPESQVKNTEVSVPETLESQVKKSESGVLKGQEAQEKKE 491


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 36.2 bits (82), Expect = 0.020
 Identities = 22/92 (23%), Positives = 43/92 (46%), Gaps = 1/92 (1%)

Query: 33   EWVESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPD 92
            E  +   G+  P ++  +S+E  +E +P+S+ VE      E    E + + + E V  P+
Sbjct: 1945 EAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPE 2004

Query: 93   TDAPQEMGDGRKAPDST-VQTAPRSLPRSAQQ 123
             +   +  +    P+S  V+  P+S    AQ+
Sbjct: 2005 AEGEMQEAEEEAQPESDGVEAQPKSEGEEAQE 2036



 Score = 32.3 bits (72), Expect = 0.29
 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 9/98 (9%)

Query: 35   VESMGGKVPPATQKAKSEENTKEEKPDSKKVE------EDLKAD--EPSSEESDLEIDKE 86
            V+   G+  P ++   ++E   E +P+S+ VE      E  KA+  E    E + + + E
Sbjct: 2071 VQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESE 2130

Query: 87   GVIEPDTDA-PQEMGDGRKAPDSTVQTAPRSLPRSAQQ 123
            G+  P+ +   Q   +G +A D+  +  P S    AQ+
Sbjct: 2131 GIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQE 2168



 Score = 31.2 bits (69), Expect = 0.64
 Identities = 19/78 (24%), Positives = 36/78 (46%), Gaps = 1/78 (1%)

Query: 40   GKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLE-IDKEGVIEPDTDAPQE 98
            G+  P ++  ++ E   E +P+S+  E      E   E   +E ++ EG  EP+++  + 
Sbjct: 1881 GEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEA 1940

Query: 99   MGDGRKAPDSTVQTAPRS 116
                  A ++  QT P S
Sbjct: 1941 QEAEEAAQEAEGQTQPES 1958



 Score = 30.8 bits (68), Expect = 0.83
 Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 11/72 (15%)

Query: 41   KVPPATQKAKSEENTKEEKPDSKKVE--EDLKADEPSSEESDLEIDKEGVIEPDTDAPQE 98
            +V P ++ A++ E  KE +P+++ VE  E    DEP SE ++ +  +E   E        
Sbjct: 1898 EVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQE-------- 1949

Query: 99   MGDGRKAPDSTV 110
              +G+  P+S V
Sbjct: 1950 -AEGQTQPESEV 1960



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 19/84 (22%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 40   GKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEM 99
            G++  A ++A+ E +  E +P S+  E      E    E D + + +GV  P+ +   + 
Sbjct: 2007 GEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQE 2066

Query: 100  GDGRKAPDSTVQTAPRSLPRSAQQ 123
             +G +  ++  +  P S    AQ+
Sbjct: 2067 AEG-EVQEAEGEAHPESEDVDAQE 2089



 Score = 30.0 bits (66), Expect = 1.4
 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 10/82 (12%)

Query: 36   ESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEI-DKEGVIEPDTD 94
            ES G + P A   A+  E   E +P+S+ VE      E   E  D+E  + E  ++P++ 
Sbjct: 1847 ESEGVEAPEAEGDAQEAEG--EAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPES- 1903

Query: 95   APQEMGDGRKAPDSTVQTAPRS 116
                  +G +AP++  +  P +
Sbjct: 1904 ------EGAEAPEAEKEAQPET 1919


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score = 35.8 bits (81), Expect = 0.026
 Identities = 20/58 (34%), Positives = 28/58 (48%)

Query: 52  EENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDGRKAPDST 109
           EE   EE  + + VE D   DE S EE +  +D+E   E + +  +E G G K    T
Sbjct: 187 EEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRET 244


>gi|82830424 gon-4-like isoform a [Homo sapiens]
          Length = 2240

 Score = 35.4 bits (80), Expect = 0.034
 Identities = 30/150 (20%), Positives = 64/150 (42%), Gaps = 2/150 (1%)

Query: 46   TQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDGRKA 105
            +Q+ +SEE   +E+    + EE+ +A+   S + + E+  E V +   + P        A
Sbjct: 1507 SQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVGD-SAEKPPTFASPETA 1565

Query: 106  PD-STVQTAPRSLPRSAQQPRFSQNTGIFSGRRSNQKMEMNFNIILEEILIKRSQQKKKT 164
            P+  T +T P    ++A + R +       G R+    + +  ++L +  I      ++ 
Sbjct: 1566 PEVETSRTPPGESIKAAGKGRNNHRARNKRGSRARASKDTSKLLLLYDEDILERDPLREQ 1625

Query: 165  SPLNYKERLFVLTKPMLTYYEGRAEQFLVI 194
              L + +      +  L +  G+ E FL +
Sbjct: 1626 KDLAFAQAYLTRVREALQHIPGKYEDFLQV 1655


>gi|5729790 CCCTC-binding factor [Homo sapiens]
          Length = 727

 Score = 35.0 bits (79), Expect = 0.044
 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 3/94 (3%)

Query: 39  GGKVPPATQKAKSE-ENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQ 97
           GG+   + +  K +  + KE+  DS+  E DL  D    EE  +EI+ E   +P T AP 
Sbjct: 588 GGETKKSKRGRKRKMRSKKEDSSDSENAEPDLD-DNEDEEEPAVEIEPEPEPQPVTPAPP 646

Query: 98  EMGDGRKAPDSTVQTAPRSLPRSAQQPRFSQNTG 131
                R  P        ++ P +  Q    QNTG
Sbjct: 647 PAKKRRGRPPGRTNQPKQNQPTAIIQVE-DQNTG 679


>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
           sapiens]
          Length = 486

 Score = 35.0 bits (79), Expect = 0.044
 Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 12/110 (10%)

Query: 17  KQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP-DSKKVEEDLKADEPS 75
           KQD S   +EE       ++   G +P A ++  + ++ KE+ P  S+K  +  +++ P 
Sbjct: 33  KQDDSPKSSEET------IQPKEGDIPKAPEE--TIQSKKEDLPKSSEKAIQPKESNIPK 84

Query: 76  SEESDLEIDKEGVIEPDTDAPQEM--GDGRKAPDSTVQTAPRSLPRSAQQ 123
           S    ++  K G I   +  P +   GD  KAP+ T+Q+    LP+S+++
Sbjct: 85  SSAKPIQ-PKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEE 133



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 4/93 (4%)

Query: 33  EWVESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVI--E 90
           E ++   G +P + ++A   +     K   + ++   + D P S E  ++  KEG I   
Sbjct: 223 EAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPK-EGDIPKSLEEAIQ-PKEGDIPKS 280

Query: 91  PDTDAPQEMGDGRKAPDSTVQTAPRSLPRSAQQ 123
           P+     + GD  K+P+  +Q     +P+S +Q
Sbjct: 281 PEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQ 313



 Score = 28.1 bits (61), Expect = 5.4
 Identities = 20/84 (23%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 41  KVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMG 100
           K P  T ++K E+  K  +   +  E D+        +  L    +  ++P    P+E  
Sbjct: 114 KAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQ--PKE-S 170

Query: 101 DGRKAPDSTVQTAPRSLPRSAQQP 124
           D  K+P+ T+Q     +P+S+ +P
Sbjct: 171 DIPKSPEETIQPKEGDIPKSSAKP 194


>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
           sapiens]
          Length = 553

 Score = 35.0 bits (79), Expect = 0.044
 Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 12/110 (10%)

Query: 17  KQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP-DSKKVEEDLKADEPS 75
           KQD S   +EE       ++   G +P A ++  + ++ KE+ P  S+K  +  +++ P 
Sbjct: 100 KQDDSPKSSEET------IQPKEGDIPKAPEE--TIQSKKEDLPKSSEKAIQPKESNIPK 151

Query: 76  SEESDLEIDKEGVIEPDTDAPQEM--GDGRKAPDSTVQTAPRSLPRSAQQ 123
           S    ++  K G I   +  P +   GD  KAP+ T+Q+    LP+S+++
Sbjct: 152 SSAKPIQ-PKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEE 200



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 4/93 (4%)

Query: 33  EWVESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVI--E 90
           E ++   G +P + ++A   +     K   + ++   + D P S E  ++  KEG I   
Sbjct: 290 EAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPK-EGDIPKSLEEAIQ-PKEGDIPKS 347

Query: 91  PDTDAPQEMGDGRKAPDSTVQTAPRSLPRSAQQ 123
           P+     + GD  K+P+  +Q     +P+S +Q
Sbjct: 348 PEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQ 380



 Score = 28.1 bits (61), Expect = 5.4
 Identities = 20/84 (23%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 41  KVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMG 100
           K P  T ++K E+  K  +   +  E D+        +  L    +  ++P    P+E  
Sbjct: 181 KAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQ--PKE-S 237

Query: 101 DGRKAPDSTVQTAPRSLPRSAQQP 124
           D  K+P+ T+Q     +P+S+ +P
Sbjct: 238 DIPKSPEETIQPKEGDIPKSSAKP 261


>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
           sapiens]
          Length = 486

 Score = 35.0 bits (79), Expect = 0.044
 Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 12/110 (10%)

Query: 17  KQDPSILHTEEMHFLREWVESMGGKVPPATQKAKSEENTKEEKP-DSKKVEEDLKADEPS 75
           KQD S   +EE       ++   G +P A ++  + ++ KE+ P  S+K  +  +++ P 
Sbjct: 33  KQDDSPKSSEET------IQPKEGDIPKAPEE--TIQSKKEDLPKSSEKAIQPKESNIPK 84

Query: 76  SEESDLEIDKEGVIEPDTDAPQEM--GDGRKAPDSTVQTAPRSLPRSAQQ 123
           S    ++  K G I   +  P +   GD  KAP+ T+Q+    LP+S+++
Sbjct: 85  SSAKPIQ-PKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEE 133



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 22/93 (23%), Positives = 43/93 (46%), Gaps = 4/93 (4%)

Query: 33  EWVESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVI--E 90
           E ++   G +P + ++A   +     K   + ++   + D P S E  ++  KEG I   
Sbjct: 223 EAIQPKEGDLPKSLEEAIQPKEGDIPKSPEEAIQPK-EGDIPKSLEEAIQ-PKEGDIPKS 280

Query: 91  PDTDAPQEMGDGRKAPDSTVQTAPRSLPRSAQQ 123
           P+     + GD  K+P+  +Q     +P+S +Q
Sbjct: 281 PEETIQPKKGDIPKSPEEAIQPKEGDIPKSPKQ 313



 Score = 28.1 bits (61), Expect = 5.4
 Identities = 20/84 (23%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 41  KVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMG 100
           K P  T ++K E+  K  +   +  E D+        +  L    +  ++P    P+E  
Sbjct: 114 KAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQ--PKE-S 170

Query: 101 DGRKAPDSTVQTAPRSLPRSAQQP 124
           D  K+P+ T+Q     +P+S+ +P
Sbjct: 171 DIPKSPEETIQPKEGDIPKSSAKP 194


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 35.0 bits (79), Expect = 0.044
 Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 2/61 (3%)

Query: 48   KAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIE--PDTDAPQEMGDGRKA 105
            K  SEE  +EE  + ++ EE+ + DE   EE + E ++E +    P    PQ +   RK 
Sbjct: 1066 KESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKR 1125

Query: 106  P 106
            P
Sbjct: 1126 P 1126



 Score = 30.0 bits (66), Expect = 1.4
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 5/80 (6%)

Query: 36   ESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDA 95
            E  GG V      AKS+E  KEE   S + E+  + D+   EE   E D+E     D DA
Sbjct: 1372 EEGGGNVEKDPDGAKSQE--KEEPEISTEKEDSARLDDHEEEE---EEDEEPSHNEDHDA 1426

Query: 96   PQEMGDGRKAPDSTVQTAPR 115
              E     ++ +   +  PR
Sbjct: 1427 DDEDDSHMESAEVEKEELPR 1446



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 22/114 (19%), Positives = 49/114 (42%), Gaps = 3/114 (2%)

Query: 43   PPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEID---KEGVIEPDTDAPQEM 99
            P   Q      ++ E +P + +  + L+  + SSEE + E D   +E   E + D  +E 
Sbjct: 1036 PAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEE 1095

Query: 100  GDGRKAPDSTVQTAPRSLPRSAQQPRFSQNTGIFSGRRSNQKMEMNFNIILEEI 153
             +  +  +  +Q++P  L +        +   +   +R  ++  +N ++  E I
Sbjct: 1096 EEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETI 1149


>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
           sapiens]
          Length = 1251

 Score = 34.3 bits (77), Expect = 0.075
 Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 9/77 (11%)

Query: 48  KAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDGRKAPD 107
           ++ S++   EE  +  K E + KA E + E ++ E +KE         PQ+  + ++ P+
Sbjct: 398 QSTSDQKLWEEVGEEAKKEAEEKAKEEAEEVAEEEAEKE---------PQDWAETKEEPE 448

Query: 108 STVQTAPRSLPRSAQQP 124
           +  + A   +P + Q P
Sbjct: 449 AEAEAASSGVPATKQHP 465


>gi|21361639 DIPB protein [Homo sapiens]
          Length = 344

 Score = 34.3 bits (77), Expect = 0.075
 Identities = 17/70 (24%), Positives = 33/70 (47%)

Query: 29  HFLREWVESMGGKVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGV 88
           H L E+V       PPA  +   +E  + +    +++E +   +  S EES+ E + E  
Sbjct: 55  HHLAEYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETE 114

Query: 89  IEPDTDAPQE 98
            E + ++ +E
Sbjct: 115 EESEDESDEE 124



 Score = 34.3 bits (77), Expect = 0.075
 Identities = 17/58 (29%), Positives = 30/58 (51%)

Query: 50  KSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDGRKAPD 107
           +SEE+++EE  D ++ E +    E    E++ E + E   +P+ +   E    RK PD
Sbjct: 124 ESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPD 181



 Score = 33.9 bits (76), Expect = 0.098
 Identities = 16/54 (29%), Positives = 33/54 (61%)

Query: 45  ATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQE 98
           A ++++SEE ++ E+    + E + ++DE S E+S+ E++ E   E + D  +E
Sbjct: 95  AGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEE 148


>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
          Length = 543

 Score = 34.3 bits (77), Expect = 0.075
 Identities = 19/56 (33%), Positives = 28/56 (50%)

Query: 43  PPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQE 98
           PP+  +A+ EE  KEE  + +  EE+  A E S E  + E   EG    +T   +E
Sbjct: 470 PPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEEEGGEGEEGEETKEAEE 525



 Score = 30.0 bits (66), Expect = 1.4
 Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 4/70 (5%)

Query: 41  KVPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEM- 99
           +V    + AK+EE  K+E P   + EE+ K D+  +EE +   ++E   E   +A +E  
Sbjct: 453 EVEETIEAAKAEE-AKDEPPSEGEAEEEEK-DKEEAEEEEAAEEEEAAKEESEEAKEEEE 510

Query: 100 -GDGRKAPDS 108
            G+G +  ++
Sbjct: 511 GGEGEEGEET 520


>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
          Length = 1312

 Score = 34.3 bits (77), Expect = 0.075
 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 1/56 (1%)

Query: 36  ESMGGKVPPATQKAKSEENT-KEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIE 90
           ES+  KV    +KAKS + T KEE  D ++ EE+ + +E   +E D + ++E   E
Sbjct: 512 ESLNIKVEAEEEKAKSGDETNKEEDEDDEEAEEEEEEEEEEEDEDDDDNNEEEEFE 567


>gi|7657441 PDGFA associated protein 1 [Homo sapiens]
          Length = 181

 Score = 33.9 bits (76), Expect = 0.098
 Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 5/93 (5%)

Query: 36  ESMGGKVPPATQKAKSEENTKE----EKPDSKKVEEDLKADEPSSEESDLEIDKEGVIE- 90
           E +  ++    QKA+ EE  KE       D KK ++ L +DE   EE D +  ++GV   
Sbjct: 21  EEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGL 80

Query: 91  PDTDAPQEMGDGRKAPDSTVQTAPRSLPRSAQQ 123
            D + P  +    K         P+ L R  ++
Sbjct: 81  IDIENPNRVAQTTKKVTQLDLDGPKELSRRERE 113


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score = 33.9 bits (76), Expect = 0.098
 Identities = 30/127 (23%), Positives = 58/127 (45%), Gaps = 4/127 (3%)

Query: 46  TQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDGRKA 105
           T + ++EE  K+EKP S K EE  + +E    ++     K    E D ++P+     +K 
Sbjct: 22  TLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAEPSEVDMNSPKSKKAKKKE 81

Query: 106 PDSTVQTAPRSLPRSAQQPRFSQNTGIFSGRRSNQKMEMNFNIILEEILIKRSQQKKKTS 165
             S    +P++  +S ++ +      + S +   +K+  N     EEI   + ++ KK  
Sbjct: 82  EPSQNDISPKT--KSLRKKKEPIEKKVVSSK--TKKVTKNEEPSEEEIDAPKPKKMKKEK 137

Query: 166 PLNYKER 172
            +N + R
Sbjct: 138 EMNGETR 144



 Score = 29.6 bits (65), Expect = 1.9
 Identities = 24/111 (21%), Positives = 45/111 (40%), Gaps = 13/111 (11%)

Query: 42  VPPATQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGD 101
           + P T+  + ++   E+K  S K ++  K +EPS EE             D   P++M  
Sbjct: 88  ISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEPSEEEI------------DAPKPKKMKK 135

Query: 102 GRKAPDSTVQTAPRSLPRSAQQPRFSQNTGIFSGRRSNQKMEMNFNIILEE 152
            ++    T + +P+ L      P    N    +   SN ++E    +  +E
Sbjct: 136 EKEMNGETREKSPK-LKNGFPHPEPDCNPSEAASEESNSEIEQEIPVEQKE 185


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.346 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,023,502
Number of Sequences: 37866
Number of extensions: 391259
Number of successful extensions: 4092
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 153
Number of HSP's successfully gapped in prelim test: 294
Number of HSP's that attempted gapping in prelim test: 2900
Number of HSP's gapped (non-prelim): 1119
length of query: 204
length of database: 18,247,518
effective HSP length: 97
effective length of query: 107
effective length of database: 14,574,516
effective search space: 1559473212
effective search space used: 1559473212
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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