Guide to the Human Genome
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Name: BTK Sequence: fasta or formatted (659aa) NCBI GI: 4557377
Description:

Bruton agammaglobulinemia tyrosine kinase

Referenced in:

Ran and Rag
RNA Polymerase and General Transcription Factors
Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.4         29           3
 C cysteine            1.8         12           2
 D aspartate           4.1         27           2
 E glutamate           8.8         58           2
 F phenylalanine       3.6         24           1
 G glycine             5.5         36           2
 H histidine           2.3         15           1
 I isoleucine          5.2         34           2
 K lysine              8.0         53           3
 L leucine             8.6         57           2
 M methionine          3.0         20           2
 N asparagine          3.5         23           1
 P proline             5.6         37           3
 Q glutamine           4.9         32           2
 R arginine            5.2         34           2
 S serine              8.2         54           2
 T threonine           3.9         26           1
 V valine              6.1         40           2
 W tryptophan          1.7         11           2
 Y tyrosine            5.6         37           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Bruton agammaglobulinemia tyrosine kinase 
TEC                   0.519   tec protein tyrosine kinase 
BMX                   0.470   BMX non-receptor tyrosine kinase 
BMX                   0.470   BMX non-receptor tyrosine kinase 
ITK                   0.469   IL2-inducible T-cell kinase 
TXK                   0.411   TXK tyrosine kinase 
ABL1                  0.237   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.237   c-abl oncogene 1, receptor tyrosine kinase isoform b...
ABL2                  0.231   arg tyrosine kinase isoform c 
ABL2                  0.231   arg tyrosine kinase isoform b 
ABL2                  0.231   arg tyrosine kinase isoform e 
ABL2                  0.231   arg tyrosine kinase isoform d 
ABL2                  0.231   arg tyrosine kinase isoform a 
LCK                   0.229   lymphocyte-specific protein tyrosine kinase precurs...
LCK                   0.229   lymphocyte-specific protein tyrosine kinase precurs...
FRK                   0.225   fyn-related kinase 
HCK                   0.225   hemopoietic cell kinase isoform p61HCK 
LYN                   0.224   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...
LYN                   0.224   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...
FYN                   0.223   protein-tyrosine kinase fyn isoform a 
BLK                   0.222   B lymphoid tyrosine kinase 
SRC                   0.221   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.221   proto-oncogene tyrosine-protein kinase SRC 
YES1                  0.221   viral oncogene yes-1 homolog 1 
FYN                   0.219   protein-tyrosine kinase fyn isoform b 
FGR                   0.215   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.215   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.215   proto-oncogene tyrosine-protein kinase FGR 
CSK                   0.185   c-src tyrosine kinase 
CSK                   0.185   c-src tyrosine kinase 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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