Guide to the Human Genome
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Search of human proteins with 239754319

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239754319 PREDICTED: defensin, beta 133 [Homo sapiens]
         (61 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239754319 PREDICTED: defensin, beta 133 [Homo sapiens]             137   2e-33
gi|239748864 PREDICTED: defensin, beta 133 [Homo sapiens]             137   2e-33
gi|239742893 PREDICTED: beta-defensin 133 [Homo sapiens]              137   2e-33
gi|22748617 defensin, beta 105A precursor [Homo sapiens]               40   4e-04
gi|83582794 beta-defensin 110 [Homo sapiens]                           40   4e-04
gi|103485141 defensin, beta 105B precursor [Homo sapiens]              40   4e-04
gi|82734214 beta-defensin 111 [Homo sapiens]                           39   7e-04
gi|22748611 defensin, beta 106A precursor [Homo sapiens]               32   0.084
gi|103485143 defensin, beta 106B precursor [Homo sapiens]              32   0.084
gi|169172908 PREDICTED: similar to beta-defensin 130 [Homo sapiens]    31   0.19 
gi|83699414 beta-defensin 130 [Homo sapiens]                           31   0.19 
gi|169202991 PREDICTED: similar to beta-defensin 130 [Homo sapiens]    31   0.24 
gi|169203490 PREDICTED: similar to beta-defensin 130 [Homo sapiens]    31   0.24 
gi|113422487 PREDICTED: similar to beta-defensin 130 [Homo sapiens]    31   0.24 
gi|82734217 beta-defensin 112 [Homo sapiens]                           31   0.24 
gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]            30   0.54 
gi|50344744 beta-defensin 108B [Homo sapiens]                          30   0.54 
gi|82734219 beta-defensin 114 [Homo sapiens]                           30   0.54 
gi|103485147 defensin, beta 107B precursor [Homo sapiens]              29   0.93 
gi|103485145 defensin, beta 107A precursor [Homo sapiens]              29   0.93 
gi|74136827 beta-defensin 134 [Homo sapiens]                           28   1.2  
gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]            28   1.6  
gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]            28   1.6  
gi|170016023 hypothetical protein LOC100130613 [Homo sapiens]          26   6.0  
gi|215982802 F-box only protein 5 isoform b [Homo sapiens]             26   7.9  
gi|6912366 F-box only protein 5 isoform a [Homo sapiens]               26   7.9  
gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens]              26   7.9  
gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens]              26   7.9  
gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens]              26   7.9  
gi|23503331 defensin, beta 123 precursor [Homo sapiens]                26   7.9  

>gi|239754319 PREDICTED: defensin, beta 133 [Homo sapiens]
          Length = 61

 Score =  137 bits (344), Expect = 2e-33
 Identities = 61/61 (100%), Positives = 61/61 (100%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNANCY 60
          MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNANCY
Sbjct: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNANCY 60

Query: 61 M 61
          M
Sbjct: 61 M 61


>gi|239748864 PREDICTED: defensin, beta 133 [Homo sapiens]
          Length = 61

 Score =  137 bits (344), Expect = 2e-33
 Identities = 61/61 (100%), Positives = 61/61 (100%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNANCY 60
          MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNANCY
Sbjct: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNANCY 60

Query: 61 M 61
          M
Sbjct: 61 M 61


>gi|239742893 PREDICTED: beta-defensin 133 [Homo sapiens]
          Length = 61

 Score =  137 bits (344), Expect = 2e-33
 Identities = 61/61 (100%), Positives = 61/61 (100%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNANCY 60
          MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNANCY
Sbjct: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNANCY 60

Query: 61 M 61
          M
Sbjct: 61 M 61


>gi|22748617 defensin, beta 105A precursor [Homo sapiens]
          Length = 78

 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 12/69 (17%)

Query: 2  KIHVFLFVLFFFLVPIATRMKCAVKDTY-----------SCFIMRGKCRHECHDFEKPIG 50
          K   FLF +FF LV + +  +  +  +            SC + RGKCR EC + EKP G
Sbjct: 6  KTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDG 65

Query: 51 FCTKLNANC 59
           C +LN  C
Sbjct: 66 NC-RLNFLC 73


>gi|83582794 beta-defensin 110 [Homo sapiens]
          Length = 62

 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYS-CFIMRGKCRHECHDFEKPIGFCTKLNANC 59
          MKI +F F+L F++  +  R     K  +  C  +RG C+  C D E   G+C K  + C
Sbjct: 1  MKIQLFFFILHFWVTILPARSNFEPKYRFERCEKVRGICKTFCDDVEYDYGYCIKWRSQC 60


>gi|103485141 defensin, beta 105B precursor [Homo sapiens]
          Length = 78

 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 12/69 (17%)

Query: 2  KIHVFLFVLFFFLVPIATRMKCAVKDTY-----------SCFIMRGKCRHECHDFEKPIG 50
          K   FLF +FF LV + +  +  +  +            SC + RGKCR EC + EKP G
Sbjct: 6  KTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDG 65

Query: 51 FCTKLNANC 59
           C +LN  C
Sbjct: 66 NC-RLNFLC 73


>gi|82734214 beta-defensin 111 [Homo sapiens]
          Length = 67

 Score = 39.3 bits (90), Expect = 7e-04
 Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 4/63 (6%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYS----CFIMRGKCRHECHDFEKPIGFCTKLN 56
          MKI +F F+L F++  +  + K     +      C I  G+C+++CH+ E  I +C +  
Sbjct: 1  MKIQLFFFILHFWVTILPAKKKYPEYGSLDLRRECRIGNGQCKNQCHENEIRIAYCIRPG 60

Query: 57 ANC 59
           +C
Sbjct: 61 THC 63


>gi|22748611 defensin, beta 106A precursor [Homo sapiens]
          Length = 65

 Score = 32.3 bits (72), Expect = 0.084
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 5/54 (9%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTK 54
          M+  +FLF + FFL P     K A  D   C  ++G C++ C   E+ I  C K
Sbjct: 1  MRTFLFLFAVLFFLTPA----KNAFFDE-KCNKLKGTCKNNCGKNEELIALCQK 49


>gi|103485143 defensin, beta 106B precursor [Homo sapiens]
          Length = 65

 Score = 32.3 bits (72), Expect = 0.084
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 5/54 (9%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTK 54
          M+  +FLF + FFL P     K A  D   C  ++G C++ C   E+ I  C K
Sbjct: 1  MRTFLFLFAVLFFLTPA----KNAFFDE-KCNKLKGTCKNNCGKNEELIALCQK 49


>gi|169172908 PREDICTED: similar to beta-defensin 130 [Homo
          sapiens]
          Length = 79

 Score = 31.2 bits (69), Expect = 0.19
 Identities = 16/60 (26%), Positives = 25/60 (41%), Gaps = 1/60 (1%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHE-CHDFEKPIGFCTKLNANC 59
          MK+H  + VL  F+  I       +     C  ++G CR + C   +  IG C +    C
Sbjct: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60


>gi|83699414 beta-defensin 130 [Homo sapiens]
          Length = 79

 Score = 31.2 bits (69), Expect = 0.19
 Identities = 16/60 (26%), Positives = 25/60 (41%), Gaps = 1/60 (1%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHE-CHDFEKPIGFCTKLNANC 59
          MK+H  + VL  F+  I       +     C  ++G CR + C   +  IG C +    C
Sbjct: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNEGKKCC 60


>gi|169202991 PREDICTED: similar to beta-defensin 130 [Homo
          sapiens]
          Length = 78

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 15/55 (27%), Positives = 24/55 (43%), Gaps = 1/55 (1%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHE-CHDFEKPIGFCTK 54
          MK+H  + VL  F+  I       +     C  ++G CR + C   +  IG C +
Sbjct: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNE 55


>gi|169203490 PREDICTED: similar to beta-defensin 130 [Homo
          sapiens]
          Length = 78

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 15/55 (27%), Positives = 24/55 (43%), Gaps = 1/55 (1%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHE-CHDFEKPIGFCTK 54
          MK+H  + VL  F+  I       +     C  ++G CR + C   +  IG C +
Sbjct: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNE 55


>gi|113422487 PREDICTED: similar to beta-defensin 130 [Homo
          sapiens]
          Length = 78

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 15/55 (27%), Positives = 24/55 (43%), Gaps = 1/55 (1%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHE-CHDFEKPIGFCTK 54
          MK+H  + VL  F+  I       +     C  ++G CR + C   +  IG C +
Sbjct: 1  MKLHSLISVLLLFVTLIPKGKTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICNE 55


>gi|82734217 beta-defensin 112 [Homo sapiens]
          Length = 113

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 10/30 (33%), Positives = 18/30 (60%)

Query: 30 SCFIMRGKCRHECHDFEKPIGFCTKLNANC 59
          SC  + G+C+++C D E  I +C +   +C
Sbjct: 53 SCTAIGGRCKNQCDDSEFRISYCARPTTHC 82


>gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 73

 Score = 29.6 bits (65), Expect = 0.54
 Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 3/59 (5%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNANC 59
          M+I V LF +FFF+  +   +    K    C    G CR  C + E  +G C      C
Sbjct: 1  MRIAVLLFAIFFFMSQV---LPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCC 56


>gi|50344744 beta-defensin 108B [Homo sapiens]
          Length = 73

 Score = 29.6 bits (65), Expect = 0.54
 Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 3/59 (5%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNANC 59
          M+I V LF +FFF+  +   +    K    C    G CR  C + E  +G C      C
Sbjct: 1  MRIAVLLFAIFFFMSQV---LPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSQPCC 56


>gi|82734219 beta-defensin 114 [Homo sapiens]
          Length = 69

 Score = 29.6 bits (65), Expect = 0.54
 Identities = 12/51 (23%), Positives = 23/51 (45%)

Query: 3  IHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCT 53
          + +F ++ F   V       C + +   C    G+C+ +C + EK I  C+
Sbjct: 1  MRIFYYLHFLCYVTFILPATCTLVNADRCTKRYGRCKRDCLESEKQIDICS 51


>gi|103485147 defensin, beta 107B precursor [Homo sapiens]
          Length = 70

 Score = 28.9 bits (63), Expect = 0.93
 Identities = 18/52 (34%), Positives = 22/52 (42%), Gaps = 1/52 (1%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFC 52
          MKI VF+      L  I  + + A+        M G C  EC  FE  IG C
Sbjct: 5  MKIFVFILAALILLAQIF-QARTAIHRALISKRMEGHCEAECLTFEVKIGGC 55


>gi|103485145 defensin, beta 107A precursor [Homo sapiens]
          Length = 70

 Score = 28.9 bits (63), Expect = 0.93
 Identities = 18/52 (34%), Positives = 22/52 (42%), Gaps = 1/52 (1%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFC 52
          MKI VF+      L  I  + + A+        M G C  EC  FE  IG C
Sbjct: 5  MKIFVFILAALILLAQIF-QARTAIHRALISKRMEGHCEAECLTFEVKIGGC 55


>gi|74136827 beta-defensin 134 [Homo sapiens]
          Length = 66

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 13/52 (25%), Positives = 23/52 (44%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFC 52
          MK  + +FV  F   P+   +     + +      G CR EC++ E  + +C
Sbjct: 1  MKPLLVVFVFLFLWDPVLAGINSLSSEMHKKCYKNGICRLECYESEMLVAYC 52


>gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 83

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 3/59 (5%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNANC 59
          ++I V LF +FFF+  +   +    K    C    G CR  C + E  +G C      C
Sbjct: 11 VRIAVLLFAIFFFMSQV---LPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCC 66


>gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 83

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 3/59 (5%)

Query: 1  MKIHVFLFVLFFFLVPIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNANC 59
          ++I V LF +FFF+  +   +    K    C    G CR  C + E  +G C      C
Sbjct: 11 VRIAVLLFAIFFFMSQV---LPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCC 66


>gi|170016023 hypothetical protein LOC100130613 [Homo sapiens]
          Length = 298

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 13/34 (38%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 16  PIATRMKCAVKDTYSCFIMRGKCRHECHDFEKPI 49
           P  TR+ C  K  +  F +RG C H  H++ +PI
Sbjct: 197 PGNTRIACRGKLAHVSFPLRGPC-HPMHNWPRPI 229


>gi|215982802 F-box only protein 5 isoform b [Homo sapiens]
          Length = 401

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 11/38 (28%), Positives = 18/38 (47%), Gaps = 4/38 (10%)

Query: 21  MKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNAN 58
           ++C     Y C++ R  C+ E   F+    +CTK   N
Sbjct: 333 IRCNSPAKYDCYLQRATCKREGCGFD----YCTKCLCN 366


>gi|6912366 F-box only protein 5 isoform a [Homo sapiens]
          Length = 447

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 11/38 (28%), Positives = 18/38 (47%), Gaps = 4/38 (10%)

Query: 21  MKCAVKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNAN 58
           ++C     Y C++ R  C+ E   F+    +CTK   N
Sbjct: 379 IRCNSPAKYDCYLQRATCKREGCGFD----YCTKCLCN 412


>gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens]
          Length = 53

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 10/31 (32%), Positives = 16/31 (51%)

Query: 17 IATRMKCAVKDTYSCFIMRGKCRHECHDFEK 47
          I T +    +   SC+I++G CR  C   E+
Sbjct: 4  ICTDLSSVCRSQKSCWIIKGHCRKNCKPGEQ 34


>gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens]
          Length = 53

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 10/31 (32%), Positives = 16/31 (51%)

Query: 17 IATRMKCAVKDTYSCFIMRGKCRHECHDFEK 47
          I T +    +   SC+I++G CR  C   E+
Sbjct: 4  ICTDLSSVCRSQKSCWIIKGHCRKNCKPGEQ 34


>gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens]
          Length = 53

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 10/31 (32%), Positives = 16/31 (51%)

Query: 17 IATRMKCAVKDTYSCFIMRGKCRHECHDFEK 47
          I T +    +   SC+I++G CR  C   E+
Sbjct: 4  ICTDLSSVCRSQKSCWIIKGHCRKNCKPGEQ 34


>gi|23503331 defensin, beta 123 precursor [Homo sapiens]
          Length = 67

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 10/32 (31%), Positives = 15/32 (46%)

Query: 28 TYSCFIMRGKCRHECHDFEKPIGFCTKLNANC 59
          T  C+ + GKCR+ C   E+   +C      C
Sbjct: 22 TQRCWNLYGKCRYRCSKKERVYVYCINNKMCC 53


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.341    0.148    0.524 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,248,944
Number of Sequences: 37866
Number of extensions: 71426
Number of successful extensions: 284
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 262
Number of HSP's gapped (non-prelim): 30
length of query: 61
length of database: 18,247,518
effective HSP length: 34
effective length of query: 27
effective length of database: 16,960,074
effective search space: 457921998
effective search space used: 457921998
T: 11
A: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.9 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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