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Search of human proteins with 239753316
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239753316 PREDICTED: similar to Rho guanine nucleotide
exchange factor 4 [Homo sapiens]
(368 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239753316 PREDICTED: similar to Rho guanine nucleotide exchan... 776 0.0
gi|15011979 Rho guanine nucleotide exchange factor 4 isoform a [... 308 4e-84
gi|15011981 Rho guanine nucleotide exchange factor 4 isoform b [... 308 4e-84
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 47 3e-05
gi|55953110 retinoblastoma protein-binding zinc finger protein i... 43 4e-04
gi|20336260 retinoblastoma protein-binding zinc finger protein i... 43 4e-04
gi|20336258 retinoblastoma protein-binding zinc finger protein i... 43 4e-04
gi|119395716 forkhead box C1 [Homo sapiens] 43 5e-04
gi|153792074 proline rich 12 [Homo sapiens] 43 5e-04
gi|38683860 insulin receptor substrate 2 [Homo sapiens] 41 0.001
gi|134142824 forkhead box D2 [Homo sapiens] 41 0.002
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 40 0.003
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 40 0.003
gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 40 0.003
gi|169202233 PREDICTED: hypothetical protein [Homo sapiens] 40 0.004
gi|24497513 homeobox A3 isoform a [Homo sapiens] 39 0.006
gi|13562112 homeobox A3 isoform a [Homo sapiens] 39 0.006
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 39 0.006
gi|239741486 PREDICTED: hypothetical protein XP_002342213 [Homo ... 39 0.006
gi|40538799 ataxin-1 ubiquitin-like interacting protein [Homo sa... 39 0.006
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] 39 0.006
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 39 0.007
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 39 0.010
gi|149408146 TOX high mobility group box family member 2 isoform... 39 0.010
gi|149408144 TOX high mobility group box family member 2 isoform... 39 0.010
gi|149408141 TOX high mobility group box family member 2 isoform... 39 0.010
gi|14249636 TOX high mobility group box family member 2 isoform ... 39 0.010
gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 39 0.010
gi|239750101 PREDICTED: hypothetical protein [Homo sapiens] 38 0.013
gi|108389176 tRNA splicing endonuclease 54 homolog [Homo sapiens] 38 0.013
>gi|239753316 PREDICTED: similar to Rho guanine nucleotide exchange
factor 4 [Homo sapiens]
Length = 368
Score = 776 bits (2005), Expect = 0.0
Identities = 368/368 (100%), Positives = 368/368 (100%)
Query: 1 MPWEEPAGEKPSCSHSQKAFHMEPAQKPCFTTDMVTWALLCISAETVRGEAPSQPRGIPH 60
MPWEEPAGEKPSCSHSQKAFHMEPAQKPCFTTDMVTWALLCISAETVRGEAPSQPRGIPH
Sbjct: 1 MPWEEPAGEKPSCSHSQKAFHMEPAQKPCFTTDMVTWALLCISAETVRGEAPSQPRGIPH 60
Query: 61 RSPVSVDDLWLEKTQRKKLQKQAHVERRLHIGAVHKDGVKCWRKTIITSPESLNLPRRSH 120
RSPVSVDDLWLEKTQRKKLQKQAHVERRLHIGAVHKDGVKCWRKTIITSPESLNLPRRSH
Sbjct: 61 RSPVSVDDLWLEKTQRKKLQKQAHVERRLHIGAVHKDGVKCWRKTIITSPESLNLPRRSH 120
Query: 121 PLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAACP 180
PLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAACP
Sbjct: 121 PLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAACP 180
Query: 181 AWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCPSESSGQTSGDLGTSS 240
AWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCPSESSGQTSGDLGTSS
Sbjct: 181 AWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCPSESSGQTSGDLGTSS 240
Query: 241 SSSAGLSPGSDSDSSGVVCGGRGGNGGMRGAVSRSWSLESLRSATAGKDAAIPAPHAPSA 300
SSSAGLSPGSDSDSSGVVCGGRGGNGGMRGAVSRSWSLESLRSATAGKDAAIPAPHAPSA
Sbjct: 241 SSSAGLSPGSDSDSSGVVCGGRGGNGGMRGAVSRSWSLESLRSATAGKDAAIPAPHAPSA 300
Query: 301 PGCLASVKPGGWKGAAGRGWNGLRHLAVSALGPDRRTAAPSGGSWSWTPLNKTALYRPGI 360
PGCLASVKPGGWKGAAGRGWNGLRHLAVSALGPDRRTAAPSGGSWSWTPLNKTALYRPGI
Sbjct: 301 PGCLASVKPGGWKGAAGRGWNGLRHLAVSALGPDRRTAAPSGGSWSWTPLNKTALYRPGI 360
Query: 361 ALVFPGTV 368
ALVFPGTV
Sbjct: 361 ALVFPGTV 368
>gi|15011979 Rho guanine nucleotide exchange factor 4 isoform a
[Homo sapiens]
Length = 690
Score = 308 bits (790), Expect = 4e-84
Identities = 143/143 (100%), Positives = 143/143 (100%)
Query: 1 MPWEEPAGEKPSCSHSQKAFHMEPAQKPCFTTDMVTWALLCISAETVRGEAPSQPRGIPH 60
MPWEEPAGEKPSCSHSQKAFHMEPAQKPCFTTDMVTWALLCISAETVRGEAPSQPRGIPH
Sbjct: 1 MPWEEPAGEKPSCSHSQKAFHMEPAQKPCFTTDMVTWALLCISAETVRGEAPSQPRGIPH 60
Query: 61 RSPVSVDDLWLEKTQRKKLQKQAHVERRLHIGAVHKDGVKCWRKTIITSPESLNLPRRSH 120
RSPVSVDDLWLEKTQRKKLQKQAHVERRLHIGAVHKDGVKCWRKTIITSPESLNLPRRSH
Sbjct: 61 RSPVSVDDLWLEKTQRKKLQKQAHVERRLHIGAVHKDGVKCWRKTIITSPESLNLPRRSH 120
Query: 121 PLSQSAPTGLNHMGWPEHTPGTA 143
PLSQSAPTGLNHMGWPEHTPGTA
Sbjct: 121 PLSQSAPTGLNHMGWPEHTPGTA 143
>gi|15011981 Rho guanine nucleotide exchange factor 4 isoform b
[Homo sapiens]
Length = 670
Score = 308 bits (790), Expect = 4e-84
Identities = 143/143 (100%), Positives = 143/143 (100%)
Query: 1 MPWEEPAGEKPSCSHSQKAFHMEPAQKPCFTTDMVTWALLCISAETVRGEAPSQPRGIPH 60
MPWEEPAGEKPSCSHSQKAFHMEPAQKPCFTTDMVTWALLCISAETVRGEAPSQPRGIPH
Sbjct: 1 MPWEEPAGEKPSCSHSQKAFHMEPAQKPCFTTDMVTWALLCISAETVRGEAPSQPRGIPH 60
Query: 61 RSPVSVDDLWLEKTQRKKLQKQAHVERRLHIGAVHKDGVKCWRKTIITSPESLNLPRRSH 120
RSPVSVDDLWLEKTQRKKLQKQAHVERRLHIGAVHKDGVKCWRKTIITSPESLNLPRRSH
Sbjct: 61 RSPVSVDDLWLEKTQRKKLQKQAHVERRLHIGAVHKDGVKCWRKTIITSPESLNLPRRSH 120
Query: 121 PLSQSAPTGLNHMGWPEHTPGTA 143
PLSQSAPTGLNHMGWPEHTPGTA
Sbjct: 121 PLSQSAPTGLNHMGWPEHTPGTA 143
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 47.0 bits (110), Expect = 3e-05
Identities = 43/145 (29%), Positives = 54/145 (37%), Gaps = 26/145 (17%)
Query: 108 TSPESLNLPRRSHPLSQSAPTGLNHMGWPEHTP---GTATHLRPLK---VLTPDSENPPS 161
+ P + PR SQ P GL + P+ TP A L PL + TP PPS
Sbjct: 246 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS 305
Query: 162 PSQ----LTIGSSPLIPPRAACPAWSLQQVRCT----------------PWTHPAAAAPP 201
PS T+ S P PP A + ++ T P PA A PP
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365
Query: 202 PPAQPSPSLWLELGPACVRAQQCPS 226
A PSP L P + Q P+
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPN 390
Score = 35.8 bits (81), Expect = 0.063
Identities = 29/117 (24%), Positives = 45/117 (38%), Gaps = 10/117 (8%)
Query: 109 SPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIG 168
+P +L LP P S A L+ + P A + L+ +PP + +
Sbjct: 357 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 416
Query: 169 SSPLIPPRAACPAWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCP 225
+SP + P A P+ + P+ AAPP PSP + P+ Q P
Sbjct: 417 ASPPVSPSATPPSQA----------PPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463
Score = 34.7 bits (78), Expect = 0.14
Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 15/120 (12%)
Query: 110 PESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGS 169
P S +L + PLS A +G + G P P + P P L
Sbjct: 228 PASRSLSSSATPLSSPARSGPSARGTPR---------------APAHPSQPKPKGLQALR 272
Query: 170 SPLIPPRAACPAWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCPSESS 229
P + P A +L + +P P+ +APP P+ P L PA +Q S S
Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 332
Score = 34.7 bits (78), Expect = 0.14
Identities = 27/76 (35%), Positives = 31/76 (40%), Gaps = 6/76 (7%)
Query: 136 PEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAACP---AWSLQQVRCTPW 192
P TP + P + P + PPSP S PP A P A LQ + P
Sbjct: 423 PSATPPSQA---PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479
Query: 193 THPAAAAPPPPAQPSP 208
PA A PP A PSP
Sbjct: 480 APPALATPPLQALPSP 495
Score = 34.7 bits (78), Expect = 0.14
Identities = 63/235 (26%), Positives = 84/235 (35%), Gaps = 42/235 (17%)
Query: 136 PEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSP-LIPPRAACPAWSL---------Q 185
P P + T P + TP + S +LT+ +P PP + P+ +L
Sbjct: 535 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 594
Query: 186 QVRCTPW---------THPAAAAPPPPAQPS---PSLWLELGPACVRAQQ---------C 224
TP AAA+PPP A+ + P+ W GPA A +
Sbjct: 595 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW-SRGPAPPLAFRGAPGAPLPWP 653
Query: 225 PSESSGQTSG---DLGTSSSSSAGLSPGS-DSDSSGVVCGGRGGNGGMRGAVSRSWSLES 280
P+ G G T SA +PG+ D S GG+ G GA SRS
Sbjct: 654 PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 713
Query: 281 LRSATAGKDAAIPAPHAPSAPGCLASVK------PGGWKGAAGRGWNGLRHLAVS 329
L G A H S LA+ + GG GA G G G A+S
Sbjct: 714 LGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALS 768
Score = 31.2 bits (69), Expect = 1.5
Identities = 51/229 (22%), Positives = 78/229 (34%), Gaps = 27/229 (11%)
Query: 124 QSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAACPAWS 183
+ AP N P +PG A+ L + + G + P R+A A +
Sbjct: 92 ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 151
Query: 184 LQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCPSESSGQTSGDLGTSSSSS 243
+ + P P PSP++ A S + S
Sbjct: 152 RRDT-----------SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV 200
Query: 244 AGLSPGSDSDSSGVVCGGRGGNGGMRGAVSRSWSLES--LRSATAGKDAAIPAPHAPSAP 301
+ S S ++ S GG++ SRS S + L S +A P AP+ P
Sbjct: 201 SSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 260
Query: 302 GCLASVKPGGWKGAAGRGWNGLRHLAVSALGPDRRTAAPSGGSWSWTPL 350
+ KP GL+ L + P R+ AAP+ G S +PL
Sbjct: 261 ---SQPKP-----------KGLQALRPPQVTPPRKDAAPALGPLSSSPL 295
>gi|55953110 retinoblastoma protein-binding zinc finger protein
isoform c [Homo sapiens]
Length = 1481
Score = 43.1 bits (100), Expect = 4e-04
Identities = 45/136 (33%), Positives = 60/136 (44%), Gaps = 13/136 (9%)
Query: 139 TPGTAT-HLRPLKVLTPDSENPPSPSQLTIGSSP--LIPP-RAACPAWSLQQVRC-TPWT 193
TP ++ L PL + T S PP P LT+ + P L+P P+ S C +P +
Sbjct: 752 TPSLSSGQLPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLS 811
Query: 194 HPAAAAP----PPPAQPSPSLWLELGPACVRAQQCP----SESSGQTSGDLGTSSSSSAG 245
+ A +P P PSPS + P A P S SS +S +SSSSS+
Sbjct: 812 NATAQSPLPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSS 871
Query: 246 LSPGSDSDSSGVVCGG 261
SP S S VV G
Sbjct: 872 PSPPPLSAISSVVSSG 887
>gi|20336260 retinoblastoma protein-binding zinc finger protein
isoform b [Homo sapiens]
Length = 1682
Score = 43.1 bits (100), Expect = 4e-04
Identities = 45/136 (33%), Positives = 60/136 (44%), Gaps = 13/136 (9%)
Query: 139 TPGTAT-HLRPLKVLTPDSENPPSPSQLTIGSSP--LIPP-RAACPAWSLQQVRC-TPWT 193
TP ++ L PL + T S PP P LT+ + P L+P P+ S C +P +
Sbjct: 953 TPSLSSGQLPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLS 1012
Query: 194 HPAAAAP----PPPAQPSPSLWLELGPACVRAQQCP----SESSGQTSGDLGTSSSSSAG 245
+ A +P P PSPS + P A P S SS +S +SSSSS+
Sbjct: 1013 NATAQSPLPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSS 1072
Query: 246 LSPGSDSDSSGVVCGG 261
SP S S VV G
Sbjct: 1073 PSPPPLSAISSVVSSG 1088
>gi|20336258 retinoblastoma protein-binding zinc finger protein
isoform a [Homo sapiens]
Length = 1718
Score = 43.1 bits (100), Expect = 4e-04
Identities = 45/136 (33%), Positives = 60/136 (44%), Gaps = 13/136 (9%)
Query: 139 TPGTAT-HLRPLKVLTPDSENPPSPSQLTIGSSP--LIPP-RAACPAWSLQQVRC-TPWT 193
TP ++ L PL + T S PP P LT+ + P L+P P+ S C +P +
Sbjct: 953 TPSLSSGQLPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLS 1012
Query: 194 HPAAAAP----PPPAQPSPSLWLELGPACVRAQQCP----SESSGQTSGDLGTSSSSSAG 245
+ A +P P PSPS + P A P S SS +S +SSSSS+
Sbjct: 1013 NATAQSPLPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSS 1072
Query: 246 LSPGSDSDSSGVVCGG 261
SP S S VV G
Sbjct: 1073 PSPPPLSAISSVVSSG 1088
>gi|119395716 forkhead box C1 [Homo sapiens]
Length = 553
Score = 42.7 bits (99), Expect = 5e-04
Identities = 51/182 (28%), Positives = 73/182 (40%), Gaps = 19/182 (10%)
Query: 121 PLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAACP 180
P +S + + + PG+ RPL + DS PP +P PP
Sbjct: 255 PKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPP--------APSAPPPHHSQ 306
Query: 181 AWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCPSESSGQTSGDLGTSS 240
+S+ + + P +AA A+ S L L A RA P + G S G SS
Sbjct: 307 GFSVDNIMTSLRGSPQSAA----AELSSGL-LASAAASSRAGIAPPLALGAYSP--GQSS 359
Query: 241 SSSAGLSPGSDSDSSGVVCGGRGGNGGMRGAVSRSWSLESLRSATAGKDAAIPAPHAPSA 300
S+ S S + SSG GG G GG GA + +L+++ AG+ H A
Sbjct: 360 LYSSPCSQTSSAGSSGGGGGGAGAAGGAGGAGTYHCNLQAMSLYAAGERGG----HLQGA 415
Query: 301 PG 302
PG
Sbjct: 416 PG 417
Score = 32.7 bits (73), Expect = 0.53
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 7/91 (7%)
Query: 154 PDSENPPSPSQLTIGSSPLIPPRAACPAWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLE 213
P + PP+P + G++P P P +Q ++ T P+ PP P P+ +L
Sbjct: 197 PGRQPPPAPPEQADGNAPGPQP----PPVRIQDIKTENGTCPS---PPQPLSPAAALGSG 249
Query: 214 LGPACVRAQQCPSESSGQTSGDLGTSSSSSA 244
A + + S SS +SG S SA
Sbjct: 250 SAAAVPKIESPDSSSSSLSSGSSPPGSLPSA 280
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 42.7 bits (99), Expect = 5e-04
Identities = 45/166 (27%), Positives = 63/166 (37%), Gaps = 23/166 (13%)
Query: 174 PPRAACPAWSLQQVRCTPWTHPAAAAPPPPAQPSPSL--WLELGPACV----RAQ-QCPS 226
PP A P Q + PA+A PPPP P+ +L +L G + RA C
Sbjct: 277 PPERALPR---QDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSP 333
Query: 227 ESSGQTSGDLG-TSSSSSAGLSPGSDSDSSGVVCGGRGGNGGMRGAVSRSWSLESLRSAT 285
G+ S G S + +G + G+ ++G G GG GG G ++
Sbjct: 334 LGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGK 393
Query: 286 AGKDAAI------PAPHAPSAPGC------LASVKPGGWKGAAGRG 319
G AA P P + + P C A+ G GA G G
Sbjct: 394 GGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAG 439
Score = 33.5 bits (75), Expect = 0.31
Identities = 43/179 (24%), Positives = 62/179 (34%), Gaps = 15/179 (8%)
Query: 103 RKTIITSPESLNLPRRSHPLSQSAPTG-----LNHMGWPEHTPG------TATHLRPLKV 151
+++I ++ +L+ P + P S P G + P PG T PL
Sbjct: 1395 QESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLE 1454
Query: 152 LTPDSENPPSPSQLTIGSSPLIPPRAACPAWSLQQVRCTPWTHPAAAAPPPPAQPSPSLW 211
P PP+P+ P PP+ A P+ V TP + P PPPP PS
Sbjct: 1455 EKPPPTPPPAPTPQPQPPPPPPPPQPALPS-PPPLVAPTPSSPPPPPLPPPPPPAMPSPP 1513
Query: 212 LELGPACVRAQQCPSESSGQTSGDLGTSSSSSAGLSPGSDSDSSGVVCGGRGGNGGMRG 270
PA P E + + D + L + + VCG G G
Sbjct: 1514 PPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHL---AKKQETAAVCGETDEEAGESG 1569
>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
Length = 1338
Score = 41.2 bits (95), Expect = 0.001
Identities = 42/139 (30%), Positives = 60/139 (43%), Gaps = 20/139 (14%)
Query: 122 LSQSAPTGLNHMGWPEHTPGTATHLRPLKVLT---------PDSENPPSPSQLTIGS-SP 171
LS S+P G TPGT++ R L+ P S P +PS +GS
Sbjct: 949 LSASSPASSLGSG----TPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDG 1004
Query: 172 LIPPRAACPAWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPA-CVRAQQCPSESSG 230
L+ P A+ P L P P+++ PPP P+P L PA V Q P +S
Sbjct: 1005 LLSPEASSPYPPLPP---RPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASS 1061
Query: 231 QTS--GDLGTSSSSSAGLS 247
+S GD G + + G++
Sbjct: 1062 LSSDTGDNGDYTEMAFGVA 1080
>gi|134142824 forkhead box D2 [Homo sapiens]
Length = 495
Score = 40.8 bits (94), Expect = 0.002
Identities = 44/175 (25%), Positives = 61/175 (34%), Gaps = 30/175 (17%)
Query: 159 PPSPSQLTIGSSPLIPPRAACPAWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPAC 218
PP P+ P P A A + C P AA PPP P+ S++ G A
Sbjct: 281 PPGPAP-----HPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAP 335
Query: 219 VRAQQCPSESSGQTSGDLG-----------TSSSSSAGLSPGSDSDSSGVV--------- 258
A P+ SG G G + +A LSP + ++G+
Sbjct: 336 APA---PASGSGPGPGPAGLPAFLGAELGCAKAFYAASLSPPAAGTAAGLPTALLRQGLK 392
Query: 259 --CGGRGGNGGMRGAVSRSWSLESLRSATAGKDAAIPAPHAPSAPGCLASVKPGG 311
GG G GG S+S++ + G A A P A+ PGG
Sbjct: 393 TDAGGGAGGGGAGAGQRPSFSIDHIMGHGGGGAAPPGAGEGSPGPPFAAAAGPGG 447
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 40.4 bits (93), Expect = 0.003
Identities = 39/111 (35%), Positives = 47/111 (42%), Gaps = 10/111 (9%)
Query: 203 PAQPSPSLWLELGPACVRAQQCPSESSGQTSGDLGTSSSSSAGLSPGSDS--DSSGVVCG 260
P P P W G VRAQQ S G+ G + SSSSAG +PG+ S SGV G
Sbjct: 188 PQPPPPRGWRGKG---VRAQQ-RGGSGGE--GASPSPSSSSAGKTPGTGSRNSGSGVAGG 241
Query: 261 GRGGNGG--MRGAVSRSWSLESLRSATAGKDAAIPAPHAPSAPGCLASVKP 309
G GG G G + L+ A AA HA + G + P
Sbjct: 242 GSGGGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHAKNGGGSSSRSSP 292
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 40.0 bits (92), Expect = 0.003
Identities = 36/125 (28%), Positives = 48/125 (38%), Gaps = 5/125 (4%)
Query: 107 ITSPESLNLPRRSHPLSQ--SAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQ 164
+T+P NLP + P Q SAP H+ P P + TP E P S +
Sbjct: 530 LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIAT 589
Query: 165 LTIGSSPLI--PPRAACPAWSLQQVRCTP-WTHPAAAAPPPPAQPSPSLWLELGPACVRA 221
+ P + PP P+ L + P P A PP A PSP L P +
Sbjct: 590 PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPS 649
Query: 222 QQCPS 226
Q P+
Sbjct: 650 PQAPN 654
Score = 38.1 bits (87), Expect = 0.013
Identities = 34/119 (28%), Positives = 43/119 (36%), Gaps = 2/119 (1%)
Query: 108 TSPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTI 167
+ P + PR SQ P GL + P+ TP L L+ PSPS
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK- 313
Query: 168 GSSPLIPPRAACPAWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCPS 226
+ P+ PP A P P APP P+ P L PA +Q PS
Sbjct: 314 -ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371
Score = 36.6 bits (83), Expect = 0.037
Identities = 41/146 (28%), Positives = 53/146 (36%), Gaps = 22/146 (15%)
Query: 109 SPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIG 168
+P SL P P S A ++ P TP P + P + PPSP
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMS----PSATPPPQA---PPPLAAPPLQVPPSPP----- 742
Query: 169 SSPLIPPRAACPAWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCPSES 228
+SP + P A P P P AAPP PSP L + P Q P
Sbjct: 743 ASPPMSPSATPP----------PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792
Query: 229 SGQTSGDLGTSSSSSAGLSPGSDSDS 254
+ L + +S G +P S S S
Sbjct: 793 ATPPLQALPSPPASFPGQAPFSPSAS 818
Score = 36.2 bits (82), Expect = 0.048
Identities = 34/125 (27%), Positives = 47/125 (37%), Gaps = 8/125 (6%)
Query: 116 PRRSHPLSQSAPTGLNHMGWPEH----TPGTATHLRPLKVLTPDSENPPSPSQ----LTI 167
P S PL+ +P+G P TP AT + TP PPSPS T+
Sbjct: 298 PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357
Query: 168 GSSPLIPPRAACPAWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCPSE 227
S P PP A P+ + ++ P P + SPSL P + + Q +
Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417
Query: 228 SSGQT 232
T
Sbjct: 418 LGSPT 422
Score = 35.0 bits (79), Expect = 0.11
Identities = 29/117 (24%), Positives = 44/117 (37%), Gaps = 10/117 (8%)
Query: 109 SPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIG 168
+P L LP P S A L+ + P A + L+ +PP + +
Sbjct: 621 APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 680
Query: 169 SSPLIPPRAACPAWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCP 225
+SP + P A P+ + P+ AAPP PSP + P+ Q P
Sbjct: 681 ASPPVSPSATPPSQA----------PPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
Score = 34.7 bits (78), Expect = 0.14
Identities = 63/235 (26%), Positives = 84/235 (35%), Gaps = 42/235 (17%)
Query: 136 PEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSP-LIPPRAACPAWSL---------Q 185
P P + T P + TP + S +LT+ +P PP + P+ +L
Sbjct: 843 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902
Query: 186 QVRCTPW---------THPAAAAPPPPAQPS---PSLWLELGPACVRAQQ---------C 224
TP AAA+PPP A+ + P+ W GPA A +
Sbjct: 903 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW-SRGPAPPLAFRGAPGAPLPWP 961
Query: 225 PSESSGQTSG---DLGTSSSSSAGLSPGS-DSDSSGVVCGGRGGNGGMRGAVSRSWSLES 280
P+ G G T SA +PG+ D S GG+ G GA SRS
Sbjct: 962 PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 1021
Query: 281 LRSATAGKDAAIPAPHAPSAPGCLASVK------PGGWKGAAGRGWNGLRHLAVS 329
L G A H S LA+ + GG GA G G G A+S
Sbjct: 1022 LGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALS 1076
Score = 31.2 bits (69), Expect = 1.5
Identities = 51/229 (22%), Positives = 78/229 (34%), Gaps = 27/229 (11%)
Query: 124 QSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAACPAWS 183
+ AP N P +PG A+ L + + G + P R+A A +
Sbjct: 101 ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 160
Query: 184 LQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCPSESSGQTSGDLGTSSSSS 243
+ + P P PSP++ A S + S
Sbjct: 161 RRDT-----------SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV 209
Query: 244 AGLSPGSDSDSSGVVCGGRGGNGGMRGAVSRSWSLES--LRSATAGKDAAIPAPHAPSAP 301
+ S S ++ S GG++ SRS S + L S +A P AP+ P
Sbjct: 210 SSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 269
Query: 302 GCLASVKPGGWKGAAGRGWNGLRHLAVSALGPDRRTAAPSGGSWSWTPL 350
+ KP GL+ L + P R+ AAP+ G S +PL
Sbjct: 270 ---SQPKP-----------KGLQALRPPQVTPPRKDAAPALGPLSSSPL 304
>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
Length = 354
Score = 40.0 bits (92), Expect = 0.003
Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 8/99 (8%)
Query: 226 SESSGQTSGDLGTSSSSSAGLSPGSDSDSSGVVCGGRGGNGGMRG------AVSRSWSLE 279
SESSGQ + +SS+SS+ + S ++ + G GGN A S WS
Sbjct: 121 SESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPA 180
Query: 280 SLRSATAGKDAAIPAP-HAPSAPGCL-ASVKPGGWKGAA 316
S+ +A ++P P APS C+ SV G AA
Sbjct: 181 SISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAA 219
>gi|169202233 PREDICTED: hypothetical protein [Homo sapiens]
Length = 381
Score = 39.7 bits (91), Expect = 0.004
Identities = 29/92 (31%), Positives = 37/92 (40%), Gaps = 12/92 (13%)
Query: 117 RRSHPLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPR 176
R L + AP G+ H+ + AT RP S + P P++ + G PR
Sbjct: 254 RGQQQLVEGAPDGVGHLHGSRGSGRAATTTRPQTTPAAASPDLPQPAERSRGE-----PR 308
Query: 177 AACPAWSLQQVRCTPWTHPAAAAPPPPAQPSP 208
A P R P PAA PPP PSP
Sbjct: 309 PAEP-------RAPPRPPPAARRPPPATAPSP 333
>gi|24497513 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 39.3 bits (90), Expect = 0.006
Identities = 36/116 (31%), Positives = 46/116 (39%), Gaps = 9/116 (7%)
Query: 149 LKVLTPDSENPPSPSQLTIGSSPLIPP--RAACPAWSLQQVRCTPWTHPAAAAPPPPAQP 206
L+ L+ PPS +G PL PP +AA PA Q P P AAPPPP+
Sbjct: 72 LRTLSAPPSQPPS-----LGEPPLHPPPPQAAPPAPQPPQPAPQP-PAPTPAAPPPPSSA 125
Query: 207 SPSLWLELGPACVRAQQCPSESSGQTSGDL-GTSSSSSAGLSPGSDSDSSGVVCGG 261
SP P A + P +S + + S + S SSG C G
Sbjct: 126 SPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCAG 181
>gi|13562112 homeobox A3 isoform a [Homo sapiens]
Length = 443
Score = 39.3 bits (90), Expect = 0.006
Identities = 36/116 (31%), Positives = 46/116 (39%), Gaps = 9/116 (7%)
Query: 149 LKVLTPDSENPPSPSQLTIGSSPLIPP--RAACPAWSLQQVRCTPWTHPAAAAPPPPAQP 206
L+ L+ PPS +G PL PP +AA PA Q P P AAPPPP+
Sbjct: 72 LRTLSAPPSQPPS-----LGEPPLHPPPPQAAPPAPQPPQPAPQP-PAPTPAAPPPPSSA 125
Query: 207 SPSLWLELGPACVRAQQCPSESSGQTSGDL-GTSSSSSAGLSPGSDSDSSGVVCGG 261
SP P A + P +S + + S + S SSG C G
Sbjct: 126 SPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCAG 181
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 39.3 bits (90), Expect = 0.006
Identities = 49/169 (28%), Positives = 64/169 (37%), Gaps = 42/169 (24%)
Query: 125 SAPTG---LNHMGWPEHT---------PGTATHLRPLKVLTPDSE--------NPPSPSQ 164
SAP+G + MG P+ + PGTA RP +PDS +P S
Sbjct: 6987 SAPSGGAPIRDMGHPQGSKQLPSTGGHPGTAQPERP----SPDSPWGQPAPFCHPKQGSA 7042
Query: 165 LTIGSSPLIPPRAACPAWSLQQVRCTPWTHPAAA-------APPPPAQPSPSLWLELGPA 217
G SP P A CP S C ++ APP PA+ SP L ++GP
Sbjct: 7043 PQEGCSPH-PAVAPCPPGSFPPGSCKEAPLVPSSPFLGQPQAPPAPAKASPPLDSKMGPG 7101
Query: 218 CV------RAQQCPSESSGQTSGDLGTSS----SSSAGLSPGSDSDSSG 256
+ + C S S + SS SS G PG D+ G
Sbjct: 7102 DISLPGRPKPGPCSSPGSASQASSSQVSSLRVGSSQVGTEPGPSLDAEG 7150
>gi|239741486 PREDICTED: hypothetical protein XP_002342213 [Homo
sapiens]
Length = 233
Score = 39.3 bits (90), Expect = 0.006
Identities = 48/167 (28%), Positives = 60/167 (35%), Gaps = 22/167 (13%)
Query: 141 GTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAACPAWSLQQVRCTPWTHPAAAAP 200
G A+ PL L P SE SPS+ RA C RCT P+ P
Sbjct: 73 GEASLTSPL-ALIPPSEPQHSPSK----------SRALCNRGLRSTSRCTQQGLPSV--P 119
Query: 201 PPPAQPSPSLWLELGPACVRAQQCPSESSGQTSGDLGTSSSSSAG-LSPGSDSDSSGVVC 259
P P P P P R Q PS S G LGT A ++P + C
Sbjct: 120 PSPLTPLPP-----SPTAPRRSQYPSPGSRVGRG-LGTGRGKLAHRVAPSKEPPERA--C 171
Query: 260 GGRGGNGGMRGAVSRSWSLESLRSATAGKDAAIPAPHAPSAPGCLAS 306
G RG + G + ++ + +A A PA AP L S
Sbjct: 172 GSRGRSTGWAASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGS 218
>gi|40538799 ataxin-1 ubiquitin-like interacting protein [Homo
sapiens]
Length = 601
Score = 39.3 bits (90), Expect = 0.006
Identities = 28/78 (35%), Positives = 34/78 (43%), Gaps = 3/78 (3%)
Query: 195 PAAAAPPPPAQPSPSLWLELGPACVRAQQCPSESSGQTSGDLGTSS--SSSAGLSPGSDS 252
PAAA P+ P P+ PA PS +SG S D G+ S SS G SPG+
Sbjct: 91 PAAATASSPSTPDPASAPSTTPASPATPAQPS-TSGSASSDAGSGSRRSSGGGPSPGAGE 149
Query: 253 DSSGVVCGGRGGNGGMRG 270
S G GG+ G
Sbjct: 150 GSPSATASILSGFGGILG 167
>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
Length = 753
Score = 39.3 bits (90), Expect = 0.006
Identities = 54/187 (28%), Positives = 77/187 (41%), Gaps = 43/187 (22%)
Query: 120 HPLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAAC 179
HP S + P +P P A+ L TP + P+P+ S L P +
Sbjct: 313 HPQSPAVPPT-----YPSGPPPAASALST----TPGNNGVPAPAA---PPSALGPKASPA 360
Query: 180 PAWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCPSESSGQTSGDLGTS 239
P+ + TP + A APP P+ PS + + P V+ PS G SG G+S
Sbjct: 361 PSHNSG----TPAPYAQAVAPPAPSGPSTT---QPRPPSVQ----PSGGGGGGSGGGGSS 409
Query: 240 SSSSAGLSPGSDSDSSGVVCGGRGGNGGMRGAVSRSWSL-----ESLRSATAGKDAAIPA 294
SSS++ S+G GG G GA S S + E S++ G +A+ A
Sbjct: 410 SSSNS---------SAG------GGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQA 454
Query: 295 PHAPSAP 301
PS P
Sbjct: 455 LGPPSGP 461
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 38.9 bits (89), Expect = 0.007
Identities = 54/223 (24%), Positives = 88/223 (39%), Gaps = 39/223 (17%)
Query: 106 IITSPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQL 165
+IT P + P+++ +S G PG L ++ D E SP
Sbjct: 2427 LITMPATRPKPKKARAAEESGAKG-------PRRPGEEAEL----LVKLDHEGVTSPKSK 2475
Query: 166 TIGSSPLIPPRAACPAWSLQQVRCTPWTHPAAA------APPPPA-------QPSPSLWL 212
+ L+ W + + ++P AA AP P A +P P L
Sbjct: 2476 KAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTF 2535
Query: 213 E-----LGPACVRAQQCPSE----SSGQTSGDLGTSSSSSAGLSPGSDSDSSGVVCGGRG 263
E P +A+Q +E SS +SG +SSSSS+ S S++ G G +
Sbjct: 2536 EDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSS-----SGSETEGEEEGDKN 2590
Query: 264 GNGGMRGAVSRSWSLESLRSATAGKDAAIPAPHAPSAPGCLAS 306
G+GG G R+ S S R+A+ ++ + + S+ +S
Sbjct: 2591 GDGGC-GTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSS 2632
Score = 37.7 bits (86), Expect = 0.017
Identities = 39/126 (30%), Positives = 51/126 (40%), Gaps = 14/126 (11%)
Query: 216 PACVRAQQCPSESSGQTSGDLGTSSSSSAGLSPGSDSDSSGVVCGGRGGNGGMRGAVSRS 275
PA + S SS +S +SSSSS+ S S S SS + + S S
Sbjct: 2612 PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671
Query: 276 WSLESLRSATAGKDAAIPAPHA-PSAPGCLASVKPGGWKGAAGRGWNGLRHLAVSALGPD 334
+ E S+ + D A PAP A PSA L P AG+ SA P
Sbjct: 2672 TTDED--SSCSSDDEAAPAPTAGPSAQAAL----PTKATKQAGKA-------RPSAHSPG 2718
Query: 335 RRTAAP 340
++T AP
Sbjct: 2719 KKTPAP 2724
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 38.5 bits (88), Expect = 0.010
Identities = 38/133 (28%), Positives = 49/133 (36%), Gaps = 23/133 (17%)
Query: 116 PRRSHPLSQSAPTGLNHMGWPEHTPGTATHLRPL--KVLTPDSENPPSPSQ----LTIGS 169
P S PL+ +P+ P P T H L ++ TP PPSPS T+ S
Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATP-HSSSLTCQLATPLPLAPPSPSAPPSLQTLPS 356
Query: 170 SPLIPPRAACPAWSLQQVRCT----------------PWTHPAAAAPPPPAQPSPSLWLE 213
P PP A + ++ T P PA A PP A PSP
Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP 416
Query: 214 LGPACVRAQQCPS 226
L P + Q P+
Sbjct: 417 LSPLATPSPQAPN 429
Score = 37.4 bits (85), Expect = 0.022
Identities = 33/122 (27%), Positives = 46/122 (37%), Gaps = 8/122 (6%)
Query: 108 TSPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPS-QLT 166
+ P + PR SQ P GL + P+ TP L L+ PSPS L
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ 314
Query: 167 IGSSPLIPPRAACPAWSLQQVRCTPWTHPAAAAPP-------PPAQPSPSLWLELGPACV 219
+ P +P + + Q P P+ +APP PPA P LG +
Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 374
Query: 220 RA 221
+A
Sbjct: 375 QA 376
Score = 35.8 bits (81), Expect = 0.063
Identities = 29/117 (24%), Positives = 45/117 (38%), Gaps = 10/117 (8%)
Query: 109 SPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIG 168
+P +L LP P S A L+ + P A + L+ +PP + +
Sbjct: 396 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 455
Query: 169 SSPLIPPRAACPAWSLQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCP 225
+SP + P A P+ + P+ AAPP PSP + P+ Q P
Sbjct: 456 ASPPVSPSATPPSQA----------PPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 502
Score = 34.7 bits (78), Expect = 0.14
Identities = 27/76 (35%), Positives = 31/76 (40%), Gaps = 6/76 (7%)
Query: 136 PEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAACP---AWSLQQVRCTPW 192
P TP + P + P + PPSP S PP A P A LQ + P
Sbjct: 462 PSATPPSQA---PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518
Query: 193 THPAAAAPPPPAQPSP 208
PA A PP A PSP
Sbjct: 519 APPALATPPLQALPSP 534
Score = 34.7 bits (78), Expect = 0.14
Identities = 63/235 (26%), Positives = 84/235 (35%), Gaps = 42/235 (17%)
Query: 136 PEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSP-LIPPRAACPAWSL---------Q 185
P P + T P + TP + S +LT+ +P PP + P+ +L
Sbjct: 574 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 633
Query: 186 QVRCTPW---------THPAAAAPPPPAQPS---PSLWLELGPACVRAQQ---------C 224
TP AAA+PPP A+ + P+ W GPA A +
Sbjct: 634 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW-SRGPAPPLAFRGAPGAPLPWP 692
Query: 225 PSESSGQTSG---DLGTSSSSSAGLSPGS-DSDSSGVVCGGRGGNGGMRGAVSRSWSLES 280
P+ G G T SA +PG+ D S GG+ G GA SRS
Sbjct: 693 PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 752
Query: 281 LRSATAGKDAAIPAPHAPSAPGCLASVK------PGGWKGAAGRGWNGLRHLAVS 329
L G A H S LA+ + GG GA G G G A+S
Sbjct: 753 LGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALS 807
Score = 31.2 bits (69), Expect = 1.5
Identities = 51/229 (22%), Positives = 78/229 (34%), Gaps = 27/229 (11%)
Query: 124 QSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAACPAWS 183
+ AP N P +PG A+ L + + G + P R+A A +
Sbjct: 101 ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 160
Query: 184 LQQVRCTPWTHPAAAAPPPPAQPSPSLWLELGPACVRAQQCPSESSGQTSGDLGTSSSSS 243
+ + P P PSP++ A S + S
Sbjct: 161 RRDT-----------SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV 209
Query: 244 AGLSPGSDSDSSGVVCGGRGGNGGMRGAVSRSWSLES--LRSATAGKDAAIPAPHAPSAP 301
+ S S ++ S GG++ SRS S + L S +A P AP+ P
Sbjct: 210 SSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 269
Query: 302 GCLASVKPGGWKGAAGRGWNGLRHLAVSALGPDRRTAAPSGGSWSWTPL 350
+ KP GL+ L + P R+ AAP+ G S +PL
Sbjct: 270 ---SQPKP-----------KGLQALRPPQVTPPRKDAAPALGPLSSSPL 304
>gi|149408146 TOX high mobility group box family member 2 isoform b
[Homo sapiens]
Length = 488
Score = 38.5 bits (88), Expect = 0.010
Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 12/129 (9%)
Query: 140 PGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAAC----PAWSL-----QQVRCT 190
PG A+ L P + S P+ T+GS L+P +A P++ L QQ+
Sbjct: 332 PGLASFLTPSDLQAFRSGASPASLARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLP 391
Query: 191 PWTHPAAAAPPPPAQPSPSLWLELGPACVRAQ--QCPSESSGQTSGDLGTSSSSSAGLSP 248
P A +PP P+P + P ++ Q PS Q + SSS SP
Sbjct: 392 PHAQGALLSPPVSMSPAPQPPVLPTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSP 451
Query: 249 G-SDSDSSG 256
G S+ SSG
Sbjct: 452 GPSNPTSSG 460
>gi|149408144 TOX high mobility group box family member 2 isoform a
[Homo sapiens]
Length = 506
Score = 38.5 bits (88), Expect = 0.010
Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 12/129 (9%)
Query: 140 PGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAAC----PAWSL-----QQVRCT 190
PG A+ L P + S P+ T+GS L+P +A P++ L QQ+
Sbjct: 350 PGLASFLTPSDLQAFRSGASPASLARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLP 409
Query: 191 PWTHPAAAAPPPPAQPSPSLWLELGPACVRAQ--QCPSESSGQTSGDLGTSSSSSAGLSP 248
P A +PP P+P + P ++ Q PS Q + SSS SP
Sbjct: 410 PHAQGALLSPPVSMSPAPQPPVLPTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSP 469
Query: 249 G-SDSDSSG 256
G S+ SSG
Sbjct: 470 GPSNPTSSG 478
>gi|149408141 TOX high mobility group box family member 2 isoform c
[Homo sapiens]
Length = 464
Score = 38.5 bits (88), Expect = 0.010
Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 12/129 (9%)
Query: 140 PGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAAC----PAWSL-----QQVRCT 190
PG A+ L P + S P+ T+GS L+P +A P++ L QQ+
Sbjct: 308 PGLASFLTPSDLQAFRSGASPASLARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLP 367
Query: 191 PWTHPAAAAPPPPAQPSPSLWLELGPACVRAQ--QCPSESSGQTSGDLGTSSSSSAGLSP 248
P A +PP P+P + P ++ Q PS Q + SSS SP
Sbjct: 368 PHAQGALLSPPVSMSPAPQPPVLPTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSP 427
Query: 249 G-SDSDSSG 256
G S+ SSG
Sbjct: 428 GPSNPTSSG 436
>gi|14249636 TOX high mobility group box family member 2 isoform c
[Homo sapiens]
Length = 464
Score = 38.5 bits (88), Expect = 0.010
Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 12/129 (9%)
Query: 140 PGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPRAAC----PAWSL-----QQVRCT 190
PG A+ L P + S P+ T+GS L+P +A P++ L QQ+
Sbjct: 308 PGLASFLTPSDLQAFRSGASPASLARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLP 367
Query: 191 PWTHPAAAAPPPPAQPSPSLWLELGPACVRAQ--QCPSESSGQTSGDLGTSSSSSAGLSP 248
P A +PP P+P + P ++ Q PS Q + SSS SP
Sbjct: 368 PHAQGALLSPPVSMSPAPQPPVLPTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSP 427
Query: 249 G-SDSDSSG 256
G S+ SSG
Sbjct: 428 GPSNPTSSG 436
>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
Length = 398
Score = 38.5 bits (88), Expect = 0.010
Identities = 39/147 (26%), Positives = 61/147 (41%), Gaps = 9/147 (6%)
Query: 201 PPPAQPSPSLWLELGPACVRAQQCPSESSGQTSGDLGTSSSSSAGLSPGSDSDSSGVVCG 260
PPP+ G + ++ S S+G + + SSS S GS SSG G
Sbjct: 232 PPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSG 291
Query: 261 GRGGNGGMRGAVSRSWSLESLRSATAGKDAAIPAPHAPSAPGCLASVKPGGWKGAAGRGW 320
GG+ G G+ S SW S +++G + PGC KPG A G G
Sbjct: 292 NSGGSRGDSGSES-SWG--SSTGSSSGNHGGSGGGNG-HKPGC---EKPG--NEARGSGE 342
Query: 321 NGLRHLAVSALGPDRRTAAPSGGSWSW 347
+G++ + + R + S G +++
Sbjct: 343 SGIQGFRGQGVSSNMRNSETSPGMFNF 369
>gi|239750101 PREDICTED: hypothetical protein [Homo sapiens]
Length = 365
Score = 38.1 bits (87), Expect = 0.013
Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 12/90 (13%)
Query: 117 RRSHPLSQSAPTGLNHMGWPEHTPGTATHLRPLKVLTPDSENPPSPSQLTIGSSPLIPPR 176
R L + AP G+ H+ + AT RP S + P P++ + G PR
Sbjct: 254 RGQQQLVEGAPDGVGHLHGSRGSGRAATTTRPQTTPAAASPDLPQPAERSRGE-----PR 308
Query: 177 AACPAWSLQQVRCTPWTHPAAAAPPPPAQP 206
A P R P PAA PPPP P
Sbjct: 309 PAEP-------RAPPRPPPAARRPPPPPAP 331
>gi|108389176 tRNA splicing endonuclease 54 homolog [Homo sapiens]
Length = 526
Score = 38.1 bits (87), Expect = 0.013
Identities = 32/110 (29%), Positives = 43/110 (39%), Gaps = 23/110 (20%)
Query: 196 AAAAPPPPAQPSPSLWLELGPACVRAQQCPSESSGQTSGDLGTSSS----SSAGLSPGSD 251
AA++PPP +QPS QCP E ++S G S G SPG
Sbjct: 227 AASSPPPCSQPS---------------QCPEEKPQESSPMKGPGGPFQLLGSLGPSPGPA 271
Query: 252 SDSSGVVCGGRGG--NGGMRGAVSRSWSLESLRSATAGKDAAIPAPHAPS 299
+ GV C G G+ GA R W+ E + D+ AP+
Sbjct: 272 RE--GVGCSWESGRAENGVTGAGKRRWNFEQISFPNMASDSRHTLLRAPA 319
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,437,065
Number of Sequences: 37866
Number of extensions: 1142819
Number of successful extensions: 8804
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 650
Number of HSP's that attempted gapping in prelim test: 7090
Number of HSP's gapped (non-prelim): 1961
length of query: 368
length of database: 18,247,518
effective HSP length: 104
effective length of query: 264
effective length of database: 14,309,454
effective search space: 3777695856
effective search space used: 3777695856
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.