Guide to the Human Genome
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Search of human proteins with 239753106

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239753106 PREDICTED: similar to hCG1817845 [Homo sapiens]
         (1090 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239753106 PREDICTED: similar to hCG1817845 [Homo sapiens]         2278   0.0  
gi|239741538 PREDICTED: similar to hCG1817845 [Homo sapiens]         1012   0.0  
gi|62122917 filaggrin family member 2 [Homo sapiens]                  112   1e-24
gi|57864582 hornerin [Homo sapiens]                                    74   6e-13
gi|60097902 filaggrin [Homo sapiens]                                   68   4e-11
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        54   6e-07
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    49   3e-05
gi|151301154 mucin 6, gastric [Homo sapiens]                           49   3e-05
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             46   2e-04
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        45   3e-04
gi|161019170 mucin 5AC [Homo sapiens]                                  44   0.001
gi|169217460 PREDICTED: similar to Mucin-6, partial [Homo sapiens]     44   0.001
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    43   0.002
gi|39995080 hypothetical protein LOC79567 [Homo sapiens]               42   0.002
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       40   0.016
gi|221316609 sperm-associated cation channel 1 [Homo sapiens]          37   0.10 
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            37   0.10 
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            37   0.10 
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            37   0.10 
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            37   0.10 
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    37   0.10 
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            37   0.10 
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            37   0.10 
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            37   0.10 
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            37   0.10 
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            37   0.10 
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula...    37   0.10 
gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula...    37   0.10 
gi|56788366 phosphatidylinositol-binding clathrin assembly prote...    35   0.39 
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]             35   0.39 

>gi|239753106 PREDICTED: similar to hCG1817845 [Homo sapiens]
          Length = 1090

 Score = 2278 bits (5903), Expect = 0.0
 Identities = 1090/1090 (100%), Positives = 1090/1090 (100%)

Query: 1    MPDLGTPGLGGTLTPDSLGDAPAAEMTAHRAFSAKELGARVYSRCTALSESLKKSDLGQS 60
            MPDLGTPGLGGTLTPDSLGDAPAAEMTAHRAFSAKELGARVYSRCTALSESLKKSDLGQS
Sbjct: 1    MPDLGTPGLGGTLTPDSLGDAPAAEMTAHRAFSAKELGARVYSRCTALSESLKKSDLGQS 60

Query: 61   VGTGAVRLQDQERRELSAPWGTVLMTRALKWKFRHHTFQGKVDAKPPRPGLAAGAMELQE 120
            VGTGAVRLQDQERRELSAPWGTVLMTRALKWKFRHHTFQGKVDAKPPRPGLAAGAMELQE
Sbjct: 61   VGTGAVRLQDQERRELSAPWGTVLMTRALKWKFRHHTFQGKVDAKPPRPGLAAGAMELQE 120

Query: 121  LSVLGHTGAPASRGQLGSAALSAHCPAVHPSALIYTVPALQLHAGGSGGSGTAFDSSRLI 180
            LSVLGHTGAPASRGQLGSAALSAHCPAVHPSALIYTVPALQLHAGGSGGSGTAFDSSRLI
Sbjct: 121  LSVLGHTGAPASRGQLGSAALSAHCPAVHPSALIYTVPALQLHAGGSGGSGTAFDSSRLI 180

Query: 181  TLQLRWLPEPVSVACPPEQRKSVDGPWSQSRAIFLQRRLGLAVRRVSGRVRVFAKHSRDA 240
            TLQLRWLPEPVSVACPPEQRKSVDGPWSQSRAIFLQRRLGLAVRRVSGRVRVFAKHSRDA
Sbjct: 181  TLQLRWLPEPVSVACPPEQRKSVDGPWSQSRAIFLQRRLGLAVRRVSGRVRVFAKHSRDA 240

Query: 241  RVRIRGVTVVGAAQGSVATHSWEAKDGPRATGPAQPKIQARFLLLQSHHSDTRALPTDTG 300
            RVRIRGVTVVGAAQGSVATHSWEAKDGPRATGPAQPKIQARFLLLQSHHSDTRALPTDTG
Sbjct: 241  RVRIRGVTVVGAAQGSVATHSWEAKDGPRATGPAQPKIQARFLLLQSHHSDTRALPTDTG 300

Query: 301  TLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGTDMGTLT 360
            TLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGTDMGTLT
Sbjct: 301  TLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGTDMGTLT 360

Query: 361  IPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGD 420
            IPAPTRDTDPGTLTIPAPTWGRSLFQH HGDAHYSSTDTGTLTIPAPTRGRSLFQH HGD
Sbjct: 361  IPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGD 420

Query: 421  AHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDT 480
            AHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDT
Sbjct: 421  AHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDT 480

Query: 481  GTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHYSSI 540
            GTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHYSSI
Sbjct: 481  GTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHYSSI 540

Query: 541  DAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYS 600
            DAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYS
Sbjct: 541  DAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYS 600

Query: 601  STDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRP 660
            STDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRP
Sbjct: 601  STDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRP 660

Query: 661  LFQHRHGDAHYSSTDTGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTG 720
            LFQHRHGDAHYSSTDTGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTG
Sbjct: 661  LFQHRHGDAHYSSTDTGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTG 720

Query: 721  HRHGDAHYSSTDVGTLTIPAPTRGRSLFQHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLT 780
            HRHGDAHYSSTDVGTLTIPAPTRGRSLFQHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLT
Sbjct: 721  HRHGDAHYSSTDVGTLTIPAPTRGRSLFQHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLT 780

Query: 781  IPALTWGRSLLQHRHGDAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIA 840
            IPALTWGRSLLQHRHGDAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIA
Sbjct: 781  IPALTWGRSLLQHRHGDAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIA 840

Query: 841  APTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSL 900
            APTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSL
Sbjct: 841  APTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSL 900

Query: 901  FQHRHGNTHYSSTDTGTLTITAPTRGGSLFQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQ 960
            FQHRHGNTHYSSTDTGTLTITAPTRGGSLFQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQ
Sbjct: 901  FQHRHGNTHYSSTDTGTLTITAPTRGGSLFQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQ 960

Query: 961  HRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGDAHYSSTDTGHRH 1020
            HRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGDAHYSSTDTGHRH
Sbjct: 961  HRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGDAHYSSTDTGHRH 1020

Query: 1021 GDAHYTSTDMGTLTIPAPIQGRSLFQHQCGDVHNSSTDAGTLTIPAVTRGRSLLQHRHGA 1080
            GDAHYTSTDMGTLTIPAPIQGRSLFQHQCGDVHNSSTDAGTLTIPAVTRGRSLLQHRHGA
Sbjct: 1021 GDAHYTSTDMGTLTIPAPIQGRSLFQHQCGDVHNSSTDAGTLTIPAVTRGRSLLQHRHGA 1080

Query: 1081 PTWGRSLFQH 1090
            PTWGRSLFQH
Sbjct: 1081 PTWGRSLFQH 1090


>gi|239741538 PREDICTED: similar to hCG1817845 [Homo sapiens]
          Length = 572

 Score = 1012 bits (2617), Expect = 0.0
 Identities = 513/591 (86%), Positives = 526/591 (89%), Gaps = 20/591 (3%)

Query: 1   MPDLGTPGLGGTLTPDSLGDAPAAEMTAHRAFSAKELGARVYSRCTALSESLKKSDLGQS 60
           MPDLGTPGLGGTLTPDSLGDAPAAEMTAHRAFSA ELGARVYSRCTALSESLKKSDLGQS
Sbjct: 1   MPDLGTPGLGGTLTPDSLGDAPAAEMTAHRAFSATELGARVYSRCTALSESLKKSDLGQS 60

Query: 61  VGTGAVRLQDQERRELSAPWGTVLMTRALKWKFRHHTFQGKVDAKPPRPGLAAGAMELQE 120
           VGTGAVRLQDQERRELSAPWGTVLMTRALKWKFRHHTFQGKVDAKPPRPGLAAG MELQE
Sbjct: 61  VGTGAVRLQDQERRELSAPWGTVLMTRALKWKFRHHTFQGKVDAKPPRPGLAAGGMELQE 120

Query: 121 LSVLGHTGAPASRGQLGSAALSAHCPAVHPSALIYTVPALQLHAGGSGGSGTAFDSSRLI 180
           LSVLGHTGAPASRGQLGSAALSAHCPAVHPSALIYTVPALQLHAGGSGGSGTAFDSSRLI
Sbjct: 121 LSVLGHTGAPASRGQLGSAALSAHCPAVHPSALIYTVPALQLHAGGSGGSGTAFDSSRLI 180

Query: 181 TLQLRWLPEPVSVACPPEQRKSVDGPWSQSRAIFLQRRLGLAVRRVSGRVRVFAKHSRDA 240
           TLQLRWLPEPVSVACPPEQRKSVDGPWSQSRAIFLQRRLGLAVRRVSGRVRVFAKHSRDA
Sbjct: 181 TLQLRWLPEPVSVACPPEQRKSVDGPWSQSRAIFLQRRLGLAVRRVSGRVRVFAKHSRDA 240

Query: 241 RVRIRGVTVVGAAQGSVATHSWEAKDGPRATGPAQPKIQARFLLLQSHHSDTRALPTDTG 300
           RVRIRGVTVVGAAQGSVATHSWEAKDGPRATGPAQPKIQARFLLLQSHHSDTRALPTD G
Sbjct: 241 RVRIRGVTVVGAAQGSVATHSWEAKDGPRATGPAQPKIQARFLLLQSHHSDTRALPTDVG 300

Query: 301 TLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGTDMGTLT 360
           TLTI APTRG++TGM T+PA T G SLFQHRHGD HYSSTD GTL I APTRGTD GTLT
Sbjct: 301 TLTIAAPTRGTNTGMFTIPAPTWGRSLFQHRHGDAHYSSTDVGTLAISAPTRGTDTGTLT 360

Query: 361 IPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGD 420
           IPAPTR TD GTLTIPAPT GRSLFQH HGD HYSSTDTGT TI APTRGRSLFQH HGD
Sbjct: 361 IPAPTRGTDTGTLTIPAPTRGRSLFQHRHGDDHYSSTDTGTFTISAPTRGRSLFQHRHGD 420

Query: 421 AHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDT 480
           AHYSST+ G     HRHG+AHYSSTDKGHR+ DAH +STDTGTLTI APT+G     TD 
Sbjct: 421 AHYSSTDKG-----HRHGDAHYSSTDKGHRYGDAHSTSTDTGTLTIAAPTRG-----TDM 470

Query: 481 GTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHYSSI 540
           GTLTI APTRGTDM  LTIPA TRGRSLFQHRHGD HY STD G     H+HGDAHYSS 
Sbjct: 471 GTLTIPAPTRGTDMGTLTIPAPTRGRSLFQHRHGDTHYSSTDTG-----HRHGDAHYSST 525

Query: 541 DAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQ 591
           D GTLTIPAPTRG     TDTGTLT+ AP RG ++      AP +GCSLFQ
Sbjct: 526 DTGTLTIPAPTRG-----TDTGTLTVPAPIRGTNMRTLTIAAPIQGCSLFQ 571



 Score =  322 bits (826), Expect = 9e-88
 Identities = 179/318 (56%), Positives = 189/318 (59%), Gaps = 77/318 (24%)

Query: 819  LFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYCSNDTG 878
            L Q  H D     TD GTLTIAAPTRG +       APTWGRS FQHRHGD HY S D G
Sbjct: 284  LLQSHHSDTRALPTDVGTLTIAAPTRGTNTGMFTIPAPTWGRSLFQHRHGDAHYSSTDVG 343

Query: 879  THTIPAPT-----GTLTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITAPTRGGSLFQHR 933
            T  I APT     GTLTIPAPTRG               TDTGTLTI APTRG SLFQHR
Sbjct: 344  TLAISAPTRGTDTGTLTIPAPTRG---------------TDTGTLTIPAPTRGRSLFQHR 388

Query: 934  HGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTD------- 986
            HG+ HYSSTDTGT T  APT+GR LFQHRHGDAHYSSTD GHRHGDAHY+STD       
Sbjct: 389  HGDDHYSSTDTGTFTISAPTRGRSLFQHRHGDAHYSSTDKGHRHGDAHYSSTDKGHRYGD 448

Query: 987  -----------------------------------MGTLTIPAPIQGRPLFQHRHGDAHY 1011
                                               MGTLTIPAP +GR LFQHRHGD HY
Sbjct: 449  AHSTSTDTGTLTIAAPTRGTDMGTLTIPAPTRGTDMGTLTIPAPTRGRSLFQHRHGDTHY 508

Query: 1012 SSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRSLFQHQCGDVHNSSTDAGTLTIPAVTRGR 1071
            SSTDTGHRHGDAHY+STD GTLTIPAP +G               TD GTLT+PA  RG 
Sbjct: 509  SSTDTGHRHGDAHYSSTDTGTLTIPAPTRG---------------TDTGTLTVPAPIRGT 553

Query: 1072 SLLQHRHGAPTWGRSLFQ 1089
            ++      AP  G SLFQ
Sbjct: 554  NMRTLTIAAPIQGCSLFQ 571



 Score =  294 bits (753), Expect = 3e-79
 Identities = 172/305 (56%), Positives = 183/305 (60%), Gaps = 72/305 (23%)

Query: 559 TDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDT 618
           TD GTLTIAAPTRG +       APT G SLFQH+HGD HYSSTD G     A    TDT
Sbjct: 297 TDVGTLTIAAPTRGTNTGMFTIPAPTWGRSLFQHRHGDAHYSSTDVGTLAISAPTRGTDT 356

Query: 619 GTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAHYSSTDTGT 678
           GTLTI A TRG               TDTGTLTI A T+GR LFQHRHGD HYSSTDTGT
Sbjct: 357 GTLTIPAPTRG---------------TDTGTLTIPAPTRGRSLFQHRHGDDHYSSTDTGT 401

Query: 679 LTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSS-------- 730
            TI APTRGRSLFQHRHG   +  +   HRHGDAHYSSTD GHR+GDAH +S        
Sbjct: 402 FTISAPTRGRSLFQHRHGDAHYSSTDKGHRHGDAHYSSTDKGHRYGDAHSTSTDTGTLTI 461

Query: 731 --------------------TDVGTLTIPAPTRGRSLFQ--------------HQHGDVH 756
                               TD+GTLTIPAPTRGRSLFQ              H+HGD H
Sbjct: 462 AAPTRGTDMGTLTIPAPTRGTDMGTLTIPAPTRGRSLFQHRHGDTHYSSTDTGHRHGDAH 521

Query: 757 YSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGTLTIPAPTQG 816
           YSSTD G LTIPAPTRGTDTGTLT+PA   G               T+M TLTI AP QG
Sbjct: 522 YSSTDTGTLTIPAPTRGTDTGTLTVPAPIRG---------------TNMRTLTIAAPIQG 566

Query: 817 RSLFQ 821
            SLFQ
Sbjct: 567 CSLFQ 571



 Score =  290 bits (742), Expect = 5e-78
 Identities = 183/347 (52%), Positives = 193/347 (55%), Gaps = 97/347 (27%)

Query: 384 LFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYS 443
           L Q  H D     TD GTLTI APTRG +      G     +   GRSLFQHRHG     
Sbjct: 284 LLQSHHSDTRALPTDVGTLTIAAPTRGTNT-----GMFTIPAPTWGRSLFQHRHG----- 333

Query: 444 STDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALT 503
                    DAHYSSTD GTL I APT+G     TDTGTLTI APTRGTD   LTIPA T
Sbjct: 334 ---------DAHYSSTDVGTLAISAPTRG-----TDTGTLTIPAPTRGTDTGTLTIPAPT 379

Query: 504 RGRSLFQHRHGDAHYCSTDMG----------RSLLQHQHGDAHYSSID------------ 541
           RGRSLFQHRHGD HY STD G          RSL QH+HGDAHYSS D            
Sbjct: 380 RGRSLFQHRHGDDHYSSTDTGTFTISAPTRGRSLFQHRHGDAHYSSTDKGHRHGDAHYSS 439

Query: 542 ----------------AGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTR 585
                            GTLTI APTRG     TD GTLTI APTRG  +      APTR
Sbjct: 440 TDKGHRYGDAHSTSTDTGTLTIAAPTRG-----TDMGTLTIPAPTRGTDMGTLTIPAPTR 494

Query: 586 GCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSST 645
           G SLFQH+HGDTHYSSTDTGHRHGDAHYSSTDTGTLTI A TRG               T
Sbjct: 495 GRSLFQHRHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIPAPTRG---------------T 539

Query: 646 DTGTLTIAARTQGRPLFQHRHGDAHYSSTDTGTLTIPAPTRGRSLFQ 692
           DTGTLT+ A  +G               T+  TLTI AP +G SLFQ
Sbjct: 540 DTGTLTVPAPIRG---------------TNMRTLTIAAPIQGCSLFQ 571



 Score =  286 bits (731), Expect = 1e-76
 Identities = 167/318 (52%), Positives = 179/318 (56%), Gaps = 91/318 (28%)

Query: 747  LFQHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMG 806
            L Q  H D     TD G LTI APTRGT+TG  TIPA TWGRSL QHRHGDAHY STD+G
Sbjct: 284  LLQSHHSDTRALPTDVGTLTIAAPTRGTNTGMFTIPAPTWGRSLFQHRHGDAHYSSTDVG 343

Query: 807  TL----------------------------TIPAPTQGRSLFQHQHGDAHYSSTDTGTLT 838
            TL                            TIPAPT+GRSLFQH+HGD HYSSTDTGT T
Sbjct: 344  TLAISAPTRGTDTGTLTIPAPTRGTDTGTLTIPAPTRGRSLFQHRHGDDHYSSTDTGTFT 403

Query: 839  IAAPTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYCS------------------------ 874
            I+APTRGRSL QH+HG   +  +   HRHGD HY S                        
Sbjct: 404  ISAPTRGRSLFQHRHGDAHYSSTDKGHRHGDAHYSSTDKGHRYGDAHSTSTDTGTLTIAA 463

Query: 875  ----NDTGTHTIPAPT-----GTLTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITAPTR 925
                 D GT TIPAPT     GTLTIPAPTRGRSLFQHRHG+THYSSTDTG         
Sbjct: 464  PTRGTDMGTLTIPAPTRGTDMGTLTIPAPTRGRSLFQHRHGDTHYSSTDTG--------- 514

Query: 926  GGSLFQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTST 985
                  HRHG+AHYSSTDTGT T PAPT+G               TDTG     A    T
Sbjct: 515  ------HRHGDAHYSSTDTGTLTIPAPTRG---------------TDTGTLTVPAPIRGT 553

Query: 986  DMGTLTIPAPIQGRPLFQ 1003
            +M TLTI APIQG  LFQ
Sbjct: 554  NMRTLTIAAPIQGCSLFQ 571



 Score =  238 bits (607), Expect = 2e-62
 Identities = 150/332 (45%), Positives = 156/332 (46%), Gaps = 134/332 (40%)

Query: 661 LFQHRHGDAHYSSTDTGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTG 720
           L Q  H D     TD GTLTI APTRG +       AP WGRSLFQHRHGDAHYSSTD G
Sbjct: 284 LLQSHHSDTRALPTDVGTLTIAAPTRGTNTGMFTIPAPTWGRSLFQHRHGDAHYSSTDVG 343

Query: 721 -------------------------------------------HRHGDAHYSSTDVGTLT 737
                                                      HRHGD HYSSTD GT T
Sbjct: 344 TLAISAPTRGTDTGTLTIPAPTRGTDTGTLTIPAPTRGRSLFQHRHGDDHYSSTDTGTFT 403

Query: 738 IPAPTRGRSLFQHQHGDVHYSSTDR----------------------------------- 762
           I APTRGRSLFQH+HGD HYSSTD+                                   
Sbjct: 404 ISAPTRGRSLFQHRHGDAHYSSTDKGHRHGDAHYSSTDKGHRYGDAHSTSTDTGTLTIAA 463

Query: 763 -------GMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGTLTIPAPTQ 815
                  G LTIPAPTRGTD GTLTIPA T GRSL QHRHGD HY STD G         
Sbjct: 464 PTRGTDMGTLTIPAPTRGTDMGTLTIPAPTRGRSLFQHRHGDTHYSSTDTG--------- 514

Query: 816 GRSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYCSN 875
                 H+HGDAHYSSTDTGTLTI APTRG                              
Sbjct: 515 ------HRHGDAHYSSTDTGTLTIPAPTRG-----------------------------T 539

Query: 876 DTGTHTIPAP-----TGTLTIPAPTRGRSLFQ 902
           DTGT T+PAP       TLTI AP +G SLFQ
Sbjct: 540 DTGTLTVPAPIRGTNMRTLTIAAPIQGCSLFQ 571



 Score =  131 bits (330), Expect = 3e-30
 Identities = 85/167 (50%), Positives = 89/167 (53%), Gaps = 16/167 (9%)

Query: 927  GSLFQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTD 986
            GS+  H   EA      TG P  P       L Q  H D     TD G     A    T+
Sbjct: 255  GSVATHSW-EAKDGPRATG-PAQPKIQARFLLLQSHHSDTRALPTDVGTLTIAAPTRGTN 312

Query: 987  MGTLTIPAPIQGRPLFQHRHGDAHYSSTDTGH-------RHGD-------AHYTSTDMGT 1032
             G  TIPAP  GR LFQHRHGDAHYSSTD G        R  D       A    TD GT
Sbjct: 313  TGMFTIPAPTWGRSLFQHRHGDAHYSSTDVGTLAISAPTRGTDTGTLTIPAPTRGTDTGT 372

Query: 1033 LTIPAPIQGRSLFQHQCGDVHNSSTDAGTLTIPAVTRGRSLLQHRHG 1079
            LTIPAP +GRSLFQH+ GD H SSTD GT TI A TRGRSL QHRHG
Sbjct: 373  LTIPAPTRGRSLFQHRHGDDHYSSTDTGTFTISAPTRGRSLFQHRHG 419



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 25/47 (53%), Positives = 26/47 (55%)

Query: 1044 LFQHQCGDVHNSSTDAGTLTIPAVTRGRSLLQHRHGAPTWGRSLFQH 1090
            L Q    D     TD GTLTI A TRG +       APTWGRSLFQH
Sbjct: 284  LLQSHHSDTRALPTDVGTLTIAAPTRGTNTGMFTIPAPTWGRSLFQH 330


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score =  112 bits (281), Expect = 1e-24
 Identities = 181/752 (24%), Positives = 258/752 (34%), Gaps = 167/752 (22%)

Query: 390  GDAHYSSTDT-----GTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSS 444
            G  H  S+D+     G+ T    T G+S  QH   +          S+   RH   H  +
Sbjct: 1498 GSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESE----------SIIHDRHRITHGQT 1547

Query: 445  TDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTR 504
             D        H  +T TG+ T     + +H  STD+   +  +    +          T 
Sbjct: 1548 GDTTRHSYSGHEQTTQTGSRTT-GRQRTSHSESTDSEVHSGGSHRPHSREH-------TY 1599

Query: 505  GRSLFQH---------RHGDAHYCSTDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTRGAH 555
            G++  QH         RHG  H    D       H H   H  S   G+ T     R +H
Sbjct: 1600 GQAGSQHEEPEFTVHERHGTTHGQIGDT----TGHSHS-GHGQSTQRGSRTT-GRQRSSH 1653

Query: 556  YSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSS 615
              S+D+   +      G S   H H   T G +  QH       S +    RHG  H  +
Sbjct: 1654 SESSDSEVHS------GVS---HTHTGHTHGQAGSQHGQ-----SESIVPERHGTTHGQT 1699

Query: 616  TDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAHYSSTD 675
             DT        TR      H H   H  +T TG+ T   R  G   +    G +  S T 
Sbjct: 1700 GDT--------TR----HAHYH---HGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTH 1744

Query: 676  TGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGT 735
            +G       T G++  QH         S+   RHG  H  + DT       H  ST  G+
Sbjct: 1745 SGH------THGQARSQHGES-----ESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGS 1793

Query: 736  LTIPAPTRGRSLFQHQHGDVHYSST--DRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQH 793
             T    + G S +    G   +S     RG     A ++  ++            S++  
Sbjct: 1794 RTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGES-----------ESIVDE 1842

Query: 794  RHGDAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQ--- 850
            RHG  H  + D         T G S  Q  HG     ST +G+ T      G S      
Sbjct: 1843 RHGTTHGQTGD---------TSGHS--QSGHGQ----STQSGSSTTGRRRSGHSESSDSE 1887

Query: 851  ------HQHGAPTWGRSQFQH---------RHGDTHYCSNDTGTHTIPAPTGTLTIPAPT 895
                  H H   T  +++ QH         RH  TH  + DT  H  P+   T+   + T
Sbjct: 1888 VHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRT 1947

Query: 896  RGRSLFQHRHGNTHYSSTDTGTLTITAPTRGGSLFQHRHGEAHYSSTDTGTPTNPAPTQG 955
             GR       G+ H   +D+   +  + T  G    H HG+A     ++G+  +      
Sbjct: 1948 TGR------RGSGHSEYSDSEGPSGVSHTHSG----HTHGQAGSHYPESGSSVH------ 1991

Query: 956  RPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGDAHYSSTD 1015
                  RHG  H  + DT       H  ST  G+ T      G   +    G +  S T 
Sbjct: 1992 -----ERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTH 2046

Query: 1016 TGHRHGDAHYTSTDMGTLTIPAPIQGRSLFQH-QCGDV-------HNSSTDAGTLTIPAV 1067
            +GH HG A     + G     + +  R    H Q GD        H  ST  G+ T    
Sbjct: 2047 SGHAHGQAGSQHGESG-----SSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRR 2101

Query: 1068 TRGRSL---------LQHRHGAPTWGRSLFQH 1090
              G S          + H H   T+G++  QH
Sbjct: 2102 GSGHSESSDSEVHSGVSHTHSGHTYGQARSQH 2133



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 164/682 (24%), Positives = 233/682 (34%), Gaps = 110/682 (16%)

Query: 392  AHYS---STDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHRHGEA---HYSST 445
            AHY    +T TG+ T      G S +    G +  S T++G     H HG+A   H  S 
Sbjct: 1706 AHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSG-----HTHGQARSQHGESE 1760

Query: 446  DKGH-RHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTR 504
               H RH   H  + DT            H  ST TG+ T    + G   +     + + 
Sbjct: 1761 SIVHERHGTIHGQTGDT-----TRHAHSGHGQSTQTGSRTTGRRSSGHSEY-----SDSE 1810

Query: 505  GRSLFQ-------HRHGDAHYCSTDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTRGAHYS 557
            G S F        H HG A     +   S++  +HG  H  + D         ++  H  
Sbjct: 1811 GHSGFSQRPHSRGHTHGQAGSQHGE-SESIVDERHGTTHGQTGDTS-----GHSQSGHGQ 1864

Query: 558  STDTGTLTIAAPTRGCSLFQ---------HRHGAPTRGCSLFQH---------QHGDTHY 599
            ST +G+ T      G S            H H   T   +  QH         +H  TH 
Sbjct: 1865 STQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHG 1924

Query: 600  SSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAART--- 656
             + DT      +H  +  TG+ T   R  G   +    G +  S T +G     A +   
Sbjct: 1925 QTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYP 1984

Query: 657  QGRPLFQHRHGDAHYSSTDTGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSS 716
            +       RHG  H  + DT         +         G    G S +    G +  S 
Sbjct: 1985 ESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSH 2044

Query: 717  TDTGHRHGDAHYSSTDVGTLTIPAPTRGRSLFQHQHGDVHYSSTDRGMLTIPAPTRGTDT 776
            T +GH HG A     + G           S    +HG  H  + D          + T  
Sbjct: 2045 THSGHAHGQAGSQHGESG-----------SSVHERHGTTHGQTGDTTRHAHSGHGQSTQR 2093

Query: 777  GTLTIPALTWGRSLLQHRHGDAHYCSTDMG-----TLTIPAPTQGRSLFQH-QHGDAHYS 830
            G+ T             R G  H  S+D       + T    T G++  QH + G A + 
Sbjct: 2094 GSRTAG-----------RRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHG 2142

Query: 831  STDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYCSNDTGTHTIPAPT--GT 888
               T        TR     Q  HG  T   S+   R   +H  S+D+  H+  +PT  G 
Sbjct: 2143 RQGTIHGQTGDTTRHG---QSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGH 2199

Query: 889  LTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITA------PTRGGSLFQHRHGEAHYSST 942
                A +R        HG    +   TG  T  A       T+ GS    R G  H  S+
Sbjct: 2200 THSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESS 2259

Query: 943  DT-----GTPTNPAPTQGRPLFQHR------HGDAHYSSTDTGH--RHGDAHY-TSTDMG 988
            D+     G+ T+    QG+   Q R      HG    +   TG   RHG + Y  ST  G
Sbjct: 2260 DSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQTG 2319

Query: 989  TLTIPAP-IQGRPLFQHRHGDA 1009
            + +  A   Q     + RHG +
Sbjct: 2320 SRSSRASHFQSHSSERQRHGSS 2341



 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 159/729 (21%), Positives = 230/729 (31%), Gaps = 128/729 (17%)

Query: 419  GDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSST 478
            G   Y S +   S F         SS    H +R    S    GT +  +   G H S +
Sbjct: 1114 GFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGS 1173

Query: 479  DTGTLTIAAPTRGTDMWMLTIPALT-RGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDA-- 535
               T +      G+D +  +   ++  G+S    ++G     ST +G+   Q     +  
Sbjct: 1174 GP-TTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTV 1232

Query: 536  --HYSSIDAGTLTIPAPTRGAHYSSTDTGTLTIA---------APTRGCSLFQHRHGA-- 582
                 +    T+     ++     ST TG+             + +   S   HRH    
Sbjct: 1233 HGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHI 1292

Query: 583  --------PTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQ 634
                    P  G ++ + Q G TH    DT       H  ST TG     +RT GR  F 
Sbjct: 1293 HTQAGSHYPKSGSTVRRRQ-GTTHGQRGDTTRHGHSGHGQSTQTG-----SRTSGRQRFS 1346

Query: 635  HRHGDAHNSSTDTG-TLTIAARTQGRPLFQHRHGDAHYSSTDTGTLTIPAPTRGRSLFQH 693
              H DA +S   +G +    ++ Q       +HG++  +  +    T             
Sbjct: 1347 --HSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHS 1404

Query: 694  RHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPAPTRGR--SLFQHQ 751
             HG      S    R G  H  S+D+    G +H   +   T        G   S    +
Sbjct: 1405 GHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGR 1464

Query: 752  HGDVHYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDM-----G 806
            HG  H  + D          + T  G+ T             R G  H  S+D      G
Sbjct: 1465 HGTTHGQTGDTTRHAHYHHGKSTQRGSST-----------TGRRGSGHSESSDSEVHSGG 1513

Query: 807  TLTIPAPTQGRSLFQH----------------QHGDA--HYSSTDTGTLTIAAPTRGRSL 848
            + T    T G+S  QH                Q GD   H  S    T    + T GR  
Sbjct: 1514 SHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQR 1573

Query: 849  LQHQHGAP----------------TWGRSQFQH---------RHGDTHYCSNDTGTHTIP 883
              H                     T+G++  QH         RHG TH    DT  H+  
Sbjct: 1574 TSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHS 1633

Query: 884  APTGTLTIPAPTRGRSLFQHRHG-----NTHYSSTDTGTLTITAPTRGG---SLFQHRHG 935
                +    + T GR    H        ++  S T TG     A ++ G   S+   RHG
Sbjct: 1634 GHGQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPERHG 1693

Query: 936  -----------EAHYS---STDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAH 981
                        AHY    +T TG+ T      G   +    G +  S T +GH HG A 
Sbjct: 1694 TTHGQTGDTTRHAHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQAR 1753

Query: 982  YTSTDMGTLTIPAPIQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQG 1041
                           +   +   RHG  H  + DT       H  ST  G+ T      G
Sbjct: 1754 SQHG-----------ESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSG 1802

Query: 1042 RSLFQHQCG 1050
             S +    G
Sbjct: 1803 HSEYSDSEG 1811



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 102/419 (24%), Positives = 144/419 (34%), Gaps = 71/419 (16%)

Query: 326  SLFQHRHGDDHYSSTDTGTLTIPAPTRGTDMGTLTIPAPTRDTDPGTLTIPAPTWGRSLF 385
            S    RHG  H  + DT        TR    G        + T  G+ T      G S +
Sbjct: 1988 SSVHERHGTTHGQTADT--------TRHGHSGH------GQSTQRGSRTTGRRASGHSEY 2033

Query: 386  QHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSST 445
                G +  S T +G               H HG A      +G S+ + RHG  H  + 
Sbjct: 2034 SDSEGHSGVSHTHSG---------------HAHGQAGSQHGESGSSVHE-RHGTTHGQTG 2077

Query: 446  DKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRG 505
            D        H  ST  G+ T      G H  S+D+   +  + T     +          
Sbjct: 2078 DTTRHAHSGHGQSTQRGSRTAGRRGSG-HSESSDSEVHSGVSHTHSGHTYGQARSQHGES 2136

Query: 506  RSLFQHRHGDAHYCSTDMGRSLLQHQHGDA-HYSSIDAGTLTIPAPTRGAHYSSTDTGTL 564
             S    R G  H  + D  R      HG + H  S   G+ T     R +H  S+D+   
Sbjct: 2137 GSAIHGRQGTIHGQTGDTTR------HGQSGHGQSTQTGSRTT-GRQRSSHSESSDSEVH 2189

Query: 565  TIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHY---SSTDTGTL 621
            + A+PT              +  S    + G TH  + DT  RH  AHY    ST  G+ 
Sbjct: 2190 SEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDT-TRH--AHYGYGQSTQRGSR 2246

Query: 622  TIAARTRGRPLFQHRHGDAHNSSTDTGTL-------------TIAAR---TQGRPLFQHR 665
            T   R  G          +  S T +G +             T+  R   T G+     R
Sbjct: 2247 TTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTR 2306

Query: 666  HGDAHY-SSTDTGTLTIPAP-TRGRSLFQHRHG-APIWGRSLFQHRHGDAHYSSTDTGH 721
            HG + Y  ST TG+ +  A   +  S  + RHG + +W       +HG    +  D GH
Sbjct: 2307 HGHSGYGQSTQTGSRSSRASHFQSHSSERQRHGSSQVW-------KHGSYGPAEYDYGH 2358


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 189/816 (23%), Positives = 291/816 (35%), Gaps = 144/816 (17%)

Query: 381  GRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSS-----TNTGRSLFQH 435
            GRS     HG     S+  G     +  +  S  QH  G  H S      + +G+S    
Sbjct: 1619 GRSSSSGQHGSGLGESSGFGHHE-SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE 1677

Query: 436  RHGEAHYSSTDKGHRHRDAHYSSTD--TGTLTIPAPTQGAHYSST-------DTGTLTIA 486
            RHG +  SS+  G     +  SS     G+ +  +P++G H S           G+ +  
Sbjct: 1678 RHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGR 1737

Query: 487  APTRG--------TDMWMLTIPALTRGRSLFQHRHGDAHYCS------------------ 520
            + +RG        + ++           +  QH  G  H+CS                  
Sbjct: 1738 SSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG 1797

Query: 521  TDMGRSLLQHQHGDAHYSSID---AGTLTIPAPTRGAHYS-STDTGTLTIAAPTRGCSLF 576
            +  G+S    QHG     S      G+ +  +P+RG H S S  + +        G S  
Sbjct: 1798 SSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSS 1857

Query: 577  QHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHR 636
              RHG+ +   S F H    +  SS  T H  G  H SS +         +RG      +
Sbjct: 1858 SGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRG-----EQ 1912

Query: 637  HGDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAHYSSTDTGTLTIPAPTRGR-------- 688
            HG +  SS+  G     +R   + L   +HG        +G+   P+P+RGR        
Sbjct: 1913 HGSSSGSSSSYGQHGSGSR---QSLGHGQHG--------SGSGQSPSPSRGRHGSGSGQS 1961

Query: 689  SLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPAPTRGRSLF 748
            S +        W  S   +  G  H  S+  GHR   +  SS           + G S  
Sbjct: 1962 SSYGPYGSGSGWSSSRGPYESGSGH--SSGLGHRESRSGQSS----GYGQHGSSSGHSST 2015

Query: 749  QHQHGDVHYSSTDRGMLTIPAPTRGT--DTGTLTIPALTWGR----SLLQHRHGDAHYCS 802
              QHG     S+  G     +    +    G+ +  +  +GR    S     HG     S
Sbjct: 2016 HGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2075

Query: 803  TDMGTLTIPAPTQGRSLFQHQHGD--------AHY--SSTDTGTLTIAAPTRGRSLLQHQ 852
                +        GRS    QHG          H+  SS  + + +      G S    Q
Sbjct: 2076 RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2135

Query: 853  HGAPTWGRSQFQHRHGDTHYCSNDTGTH-------TIPAPTGTLTIPAPTRGRSLFQHRH 905
            HG+ + G+S    RHG +   S+  G H       +     G+ +  +P+RGR    H  
Sbjct: 2136 HGSRS-GQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR----HGS 2190

Query: 906  GNTHYSS-----TDTGTLTITAP--TRGG--SLF-QHRHGEAHYSS-TDTGTPTNPAPTQ 954
            G+ H SS     + +G  +   P  +R G  S+F QH  G  H S+ +  G+ +    +Q
Sbjct: 2191 GSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ 2250

Query: 955  GR--------PLFQHRHGDAHYSSTDTGHRHGDAHYTS-TDMGTLTIPAPIQGRPLFQHR 1005
            G+          F         SS+   H  G +  +S    G+ +  +P +GR    H 
Sbjct: 2251 GQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGR----HG 2306

Query: 1006 HGDAHYSS----------TDTGHRHGDAHYTSTDMGTLTIPAPIQGRSLFQHQCGDVHNS 1055
             G  H SS          + +  RHG     S+  G     +  Q     QH  G  H+S
Sbjct: 2307 SGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHE-SSSWQSSGYTQHGSGSGHSS 2365

Query: 1056 STDAGTLTIPAVTRGRSLLQHRHGAPTWGRSLF-QH 1090
            S +           G+S    RHG+ +   S + QH
Sbjct: 2366 SYEQ-----HGSRSGQSSRGERHGSSSGSSSSYGQH 2396



 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 175/758 (23%), Positives = 262/758 (34%), Gaps = 127/758 (16%)

Query: 381  GRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSS-----TNTGRSLFQH 435
            GRS     HG     S+  G     +  +  S  QH  G  H S      + +G+S    
Sbjct: 1149 GRSSSSGQHGSGLGESSGFGHHE-SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE 1207

Query: 436  RHGEAHYSSTDKGHRHRDAHYSSTD--TGTLTIPAPTQGAHYSST-------DTGTLTIA 486
            RHG +  SS+  G     +  SS     G+ +  +P++G H S           G+ +  
Sbjct: 1208 RHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGR 1267

Query: 487  APTRG--------TDMWMLTIPALTRGRSLFQHRHGDAHYCS-----TDMGRSLLQHQHG 533
            + +RG        + ++           +  QH  G  H+CS     +  G+S    Q G
Sbjct: 1268 SSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEG 1327

Query: 534  DA--------HYSSIDA--------GTLTIPAPTRGAHYS-STDTGTLTIAAPTRGCSLF 576
             +        H  S  +        G  +  +P+RG H S S  + +        G S  
Sbjct: 1328 SSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSS 1387

Query: 577  QHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHR 636
              RHG+ +   S F H    +  SS  T H  G  H SS +         +RG      R
Sbjct: 1388 SGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRG-----ER 1442

Query: 637  HGDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAHYSSTDTGTLTIPAPTRGRSLFQHRHG 696
            HG +  SS+  G     +R   + L   +HG        +G+   P+P+RG      RHG
Sbjct: 1443 HGSSSGSSSSYGQHGSGSR---QSLGHGQHG--------SGSGQSPSPSRG------RHG 1485

Query: 697  APIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPAPTRGRSLFQHQHGDVH 756
            +     S +      + +SS+   +  G +H S      L       G+S    QHG   
Sbjct: 1486 SGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSG-----LGHRESRSGQSSGYGQHGSSS 1540

Query: 757  YSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGTLTIPAPTQG 816
              S+  G       T G  +      A + G+S    +HG     S+  G         G
Sbjct: 1541 GHSSTHGQ---HGSTSGQSSSCGQHGASS-GQSSSHGQHGSGSSQSSGYGR---QGSGSG 1593

Query: 817  RSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYCSND 876
            +S    Q G     S   G         GRS    QHG+     S F H    +   S+ 
Sbjct: 1594 QSPGHGQRGSGSRQSPSYGR---HGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSY 1650

Query: 877  TGTHTIPAPTGTLTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITAPTRGGSLFQHRHGE 936
            +   +    +          G+S    RHG++  SS+  G              QH  G 
Sbjct: 1651 SQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYG--------------QHGSGS 1696

Query: 937  AHYSSTD-TGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAP 995
               S     G+ +  +P++GR    H  G  H SS     +HG     S+  G      P
Sbjct: 1697 RQSSGHGRQGSGSGQSPSRGR----HGSGLGHSSSHG---QHGSGSGRSSSRG------P 1743

Query: 996  IQGRP-----LFQHRHGDAHYSSTDTGHRHGDAHY--------TSTDMGTLTIPAPIQGR 1042
             + R        QH  G  H SS  + H  G  H+        TS    T        G+
Sbjct: 1744 YESRSGHSSVFGQHESGSGH-SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQ 1802

Query: 1043 SLFQHQCGDVHNSSTDAGTLTIPAVTRGRSLLQHRHGA 1080
            S    Q G   + S+  G         G+S  + RHG+
Sbjct: 1803 SSSHGQHGSGSSQSSSYGQ---QGSGSGQSPSRGRHGS 1837



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 163/741 (21%), Positives = 243/741 (32%), Gaps = 137/741 (18%)

Query: 381  GRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHRHGEA 440
            G+   QH     H+SS             G +  Q      H SS+    S  QH     
Sbjct: 825  GQGYSQHGSASGHFSSQGR---------HGSTSGQSSSSGQHDSSSGQSSSYGQHESASH 875

Query: 441  HYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPT-RGTDMWMLTI 499
            H S   +              G+ +  +P+ G H S +   + +    +  G        
Sbjct: 876  HASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHK 935

Query: 500  PALTRGRSLFQHRHGDAHYCSTDM-----GRSLLQHQHGDAHYSSID------------- 541
             +  +     QH  G  H  S +      G+S    QHG +  SS               
Sbjct: 936  SSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLG 995

Query: 542  -----AGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQ-----------HRHGAPTR 585
                 +G+   P+P+RG H S +  G  +   P R  S +            H  G   R
Sbjct: 996  HGQHGSGSGQSPSPSRGRHGSGS--GQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHR 1053

Query: 586  GCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSST 645
                 Q      H SS+     HG    +S  + +      + G+     +HG   + S+
Sbjct: 1054 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSS 1113

Query: 646  DTGTLTIAARTQGRPLFQHR-HGDAHYSSTDTGTLTIPAPTRGRSLFQHRHGAPIWGRSL 704
              G        QG    Q   HG     S  + +        GRS    +HG+ +   S 
Sbjct: 1114 GYGR-------QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSG 1166

Query: 705  FQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPAPTRGR--------SLFQHQHGDVH 756
            F H    +  SS+ + H  G  H S            +RG         S    QHG   
Sbjct: 1167 FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGS 1226

Query: 757  YSSTDRGML---TIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGTLTIPAP 813
              S+  G     +  +P+RG     L       G S    +HG     S+  G      P
Sbjct: 1227 RQSSGHGRQGSGSGHSPSRGRHGSGL-------GHSSSHGQHGSGSGRSSSRG------P 1273

Query: 814  TQGRS-----LFQHQHGDAH---YSSTDTGTLTIAA-----PTRGRSLLQHQHGAPTWGR 860
             + RS       QH+ G  H   YS   +G+    +      T G+S    Q G+ T   
Sbjct: 1274 YESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQS 1333

Query: 861  SQFQHRHGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGNTH---YSSTDTGT 917
            S + HR G     S+  G H      G  +  +P+RGR    H  G+ H   Y    +G+
Sbjct: 1334 SSYGHR-GSGSSQSSGYGRH------GAGSGQSPSRGR----HGSGSGHSSSYGQHGSGS 1382

Query: 918  LTITAPTRGGSLFQHRHGEAHY--SSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGH 975
               ++  R GS      G  H+  SS  +   T      G      +HG +    +  G 
Sbjct: 1383 GWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHG-SRSGQSSRGE 1441

Query: 976  RHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTI 1035
            RHG +  +S+  G                +HG     S   G +HG         G+   
Sbjct: 1442 RHGSSSGSSSSYG----------------QHGSGSRQSLGHG-QHGS--------GSGQS 1476

Query: 1036 PAPIQGRSLFQHQCGDVHNSS 1056
            P+P +GR    H  G   +SS
Sbjct: 1477 PSPSRGR----HGSGSGQSSS 1493



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 164/685 (23%), Positives = 233/685 (34%), Gaps = 142/685 (20%)

Query: 377  APTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHR 436
            +P++GR      HG     S+ +G        R  S      G  H SS+       QH 
Sbjct: 903  SPSYGR------HGSGSGRSSSSG--------RHGSGSGQSSGFGHKSSSGQSSGYTQHG 948

Query: 437  HGEAHYSSTDK-----GHRHRDAHYSSTD-----------------------TGTLTIPA 468
             G  H SS ++     G   R   + S+                        +G+   P+
Sbjct: 949  SGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 1008

Query: 469  PTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLL 528
            P++G H S   +G  +   P R    W  +      G     H  G  H  S   G+S  
Sbjct: 1009 PSRGRHGSG--SGQSSSYGPYRSGSGWSSSRGPYESGSG---HSSGLGHRESRS-GQSSG 1062

Query: 529  QHQHGDAHYSSIDAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCS 588
              QHG +   S           T G H S            T G S    +HGA + G S
Sbjct: 1063 YGQHGSSSGHS----------STHGQHGS------------TSGQSSSCGQHGA-SSGQS 1099

Query: 589  LFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTG 648
                QHG     S+  G R G     S   G     + +R  P +  RHG     S+ +G
Sbjct: 1100 SSHGQHGSGSSQSSGYG-RQGSGSGQSPGHGQR--GSGSRQSPSY-GRHGSGSGRSSSSG 1155

Query: 649  TLTIAARTQGRPLFQHRHGDAHYSST-DTGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQH 707
                     G  L +      H SS+  + + +      G S    +HG+   G+S    
Sbjct: 1156 -------QHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS-GQSSRGE 1207

Query: 708  RHG-----DAHYSSTDTGHRHGDAHYSSTDVGTLTIPAPTRGR-------SLFQHQHGDV 755
            RHG      +HY    +G R    H      G+ +  +P+RGR       S    QHG  
Sbjct: 1208 RHGSSSGSSSHYGQHGSGSRQSSGHGRQ---GSGSGHSPSRGRHGSGLGHSSSHGQHGSG 1264

Query: 756  HYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRS--LLQHRHGDAHYCSTDMGTLTIPAP 813
               S+ RG    P  +R   +          G S    QH  G  H+CS           
Sbjct: 1265 SGRSSSRG----PYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ-----HGS 1315

Query: 814  TQGRSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYC 873
            T G+S    Q G +   S+  G          +S    +HGA + G+S  + RHG     
Sbjct: 1316 TSGQSSTFDQEGSSTGQSSSYGH---RGSGSSQSSGYGRHGAGS-GQSPSRGRHGSGSGH 1371

Query: 874  SNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITAPTRGGSLFQHR 933
            S+  G H                G S    RHG+    S+  G    ++    G   QH 
Sbjct: 1372 SSSYGQH------------GSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCT-QHG 1418

Query: 934  HGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTST-----DMG 988
             G  H SS +     +   ++G      RHG +  SS+  G +HG     S        G
Sbjct: 1419 SGSGHSSSYEQHGSRSGQSSRG-----ERHGSSSGSSSSYG-QHGSGSRQSLGHGQHGSG 1472

Query: 989  TLTIPAPIQGRPLFQHRHGDAHYSS 1013
            +   P+P +GR    H  G    SS
Sbjct: 1473 SGQSPSPSRGR----HGSGSGQSSS 1493



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 135/576 (23%), Positives = 195/576 (33%), Gaps = 112/576 (19%)

Query: 386  QHXHGDAHYSST-DTGTLTIPAPTRGRSLFQHXHGDAHYSS-----TNTGRSLFQHRHGE 439
            QH  G +  SS    G+ +  +P+RGR    H  G  H SS     + +G S    RHG 
Sbjct: 2278 QHGSGSSQSSSYGQQGSGSGQSPSRGR----HGSGSGHSSSYGQHGSGSGWSSSSGRHGS 2333

Query: 440  AHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTI 499
                S+  GH    +  SS  T        +   H SS +         +RG        
Sbjct: 2334 GSGQSSGFGHHESSSWQSSGYT-----QHGSGSGHSSSYEQHGSRSGQSSRG-------- 2380

Query: 500  PALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHYSSID-----AGTLTIPAPTRGA 554
                        RHG +   S+  G      QHG     S+      +G+   P+P+RG 
Sbjct: 2381 -----------ERHGSSSGSSSSYG------QHGSGSRQSLGHGQHGSGSGQSPSPSRGR 2423

Query: 555  H---------YSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYSSTDTG 605
            H         YS   +G+   ++     S   H  G   R     Q      H SS+   
Sbjct: 2424 HGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHS 2483

Query: 606  HRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQHR 665
              HG    +S  + +      + G+     +HG   + S+  G        QG    Q  
Sbjct: 2484 STHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR-------QGSGSGQSP 2536

Query: 666  -HGDAHYSSTDTGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHRHG 724
             HG     S  + +        GRS    +HG+ +   S F H    +  SS+ + H  G
Sbjct: 2537 GHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG 2596

Query: 725  DAHYSSTDVGTLTIPAPTRGR--------SLFQHQHGDVHYSSTDRGML---TIPAPTRG 773
              H S            +RG         S    QHG     S+  G     +  +P+RG
Sbjct: 2597 SGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRG 2656

Query: 774  TDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGTLTIPAPTQGR----SLF-QHQHGDAH 828
                 L       G S    +HG     S+  G      P + R    S+F QH+ G  H
Sbjct: 2657 RHGSGL-------GHSSSHGQHGSGSGRSSSRG------PYESRLGHSSVFGQHESGSGH 2703

Query: 829  ---YSSTDTGTLTIAA-----PTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYCSNDTGTH 880
               YS   +G+    +      T G+S    Q G+ T   S + HR G     S+  G H
Sbjct: 2704 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHR-GSGSSQSSGYGRH 2762

Query: 881  TIPAPTGTLTIPAPTRGRSLFQHRHGNTHYSSTDTG 916
                            G+SL   RHG+    S+  G
Sbjct: 2763 ------------GAGSGQSLSHGRHGSGSGQSSSYG 2786



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 153/677 (22%), Positives = 229/677 (33%), Gaps = 111/677 (16%)

Query: 386  QHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGR--SLFQHRHGEAHYS 443
            +H  G  H SS           T G++     HG +   S++ G+  S  +H  G   +S
Sbjct: 363  KHGSGSGHSSSQGQH-----GSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHS 417

Query: 444  S---TDKGHRHRDAHY----SSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWM 496
            S      GH  R +      SS   GT    + + G + S +   +      +       
Sbjct: 418  SGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSG 477

Query: 497  LTIPALTRGRSLFQHRHGDAHYCST-------DMGRSLLQHQHGDAHYSSID-----AGT 544
             T      G S    +HG     S+         G S    QHG     S+      +G+
Sbjct: 478  YTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGS 537

Query: 545  LTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYSSTDT 604
               P+P+RG H S +           +  S   H +G+  R  S   ++ G  H  S+  
Sbjct: 538  GQSPSPSRGRHESGS----------RQSSSYGPHGYGSG-RSSSRGPYESGSGH--SSGL 584

Query: 605  GHRHGDAHYSST--DTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLF 662
            GH+   +  SS     G+ +  + T G+      HG     S+  G       T G+   
Sbjct: 585  GHQESRSGQSSGYGQHGSSSGHSSTHGQ------HGSTSGQSSSCGQ---HGATSGQSSS 635

Query: 663  QHRHGDAHYSSTDTGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHR 722
              +HG     S+  G         G+S  + RHG+  +G S    +HG     S+  G  
Sbjct: 636  HGQHGSGSSQSSRYGQ---QGSGSGQSPSRGRHGSD-FGHSSSYGQHGSGSGWSSSNGP- 690

Query: 723  HGDAHYSSTDVGTLTIPAPTRGRSLFQHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLTIP 782
            HG     S+  G  +    + G S  QH  G  H S   +        +R    G+ +  
Sbjct: 691  HGSVSGQSSGFGHKSGSGQSSGYS--QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGL 748

Query: 783  ALTWGR----SLLQHRHGDAHYCSTDMGTLTIPAPTQGRSLFQHQHGDA--------HYS 830
            + ++G+    S     HG     S    +      + G S    QHG          HY 
Sbjct: 749  SSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYE 808

Query: 831  STDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYCSNDTGTHTIPAPTGTLT 890
            S             G      QHG+ + G    Q RHG T   S+ +G H          
Sbjct: 809  SGSGQASGFGQHESGSGQGYSQHGSAS-GHFSSQGRHGSTSGQSSSSGQHD--------- 858

Query: 891  IPAPTRGRSLFQHRHGNTHYSSTDTGTLTITAPTRGGSLFQHRHGEAHYSST---DTGTP 947
              +  +  S  QH   + H S             RG      RHG     S      G+ 
Sbjct: 859  -SSSGQSSSYGQHESASHHASG------------RG------RHGSGSGQSPGHGQRGSG 899

Query: 948  TNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHG 1007
            +  +P+ G      RHG     S+ +G RHG     S+  G  +      G    QH  G
Sbjct: 900  SGQSPSYG------RHGSGSGRSSSSG-RHGSGSGQSSGFGHKSSSGQSSG--YTQHGSG 950

Query: 1008 DAHYSSTDT-GHRHGDA 1023
              H SS +  G R G +
Sbjct: 951  SGHSSSYEQHGSRSGQS 967



 Score = 57.8 bits (138), Expect = 6e-08
 Identities = 169/746 (22%), Positives = 256/746 (34%), Gaps = 132/746 (17%)

Query: 377  APTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHR 436
            +P +G    QH  G    SS DT          G    Q      H SS+       QH 
Sbjct: 202  SPNYG----QHGSGSGQSSSNDT---------HGSGSGQSSGFSQHKSSSGQSSGYSQHG 248

Query: 437  HGEAHYSS----------TDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIA 486
             G  H S           + +G RHR +  SS+  G            + S    +L   
Sbjct: 249  SGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYG-----------QHGSGSRQSLGHG 297

Query: 487  APTRGTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHYSSIDAGTLT 546
                G+           +  S  +H  G  H  S     S   + +   HY S    T  
Sbjct: 298  RQGSGS----------RQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSG 347

Query: 547  IPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYSSTDTGH 606
                  G H S +            G S    +HG+ + G S  Q QHG T   ++ +G 
Sbjct: 348  F-----GQHESGS------------GQSSGYSKHGSGS-GHSSSQGQHGSTSGQASSSG- 388

Query: 607  RHGDAHYSSTDTGTLTIAAR-TRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQHR 665
            +HG +   S+  G    A+R + GR   QH  G   +               G+     +
Sbjct: 389  QHGSSSRQSSSYGQHESASRHSSGRG--QHSSGSGQSPGHGQ-----RGSGSGQSPSSGQ 441

Query: 666  HGDAHYSSTDTGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGD 725
            HG     S+ +G     + +   S F H   +        QH  G  H S    GH    
Sbjct: 442  HGTGFGRSSSSGPYV--SGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSS----GHGQHG 495

Query: 726  AHYSSTDVGTLTIPAPTRGRSLFQHQHG---DVHYSSTDRGMLTIPAPTRG------TDT 776
            +    +  G     +     S  QH  G    + +S    G    P+P+RG        +
Sbjct: 496  SRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQS 555

Query: 777  GTLTIPALTWGRSLLQHRHGDAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGT 836
             +        GRS  +  +      S+ +G         G+S    QHG    SS  + T
Sbjct: 556  SSYGPHGYGSGRSSSRGPYESGSGHSSGLGH---QESRSGQSSGYGQHGS---SSGHSST 609

Query: 837  LTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYCSNDTGTHTIPAPTGTLTIPAPTR 896
                  T G+S    QHGA T G+S    +HG     S+  G        G+ +  +P+R
Sbjct: 610  HGQHGSTSGQSSSCGQHGA-TSGQSSSHGQHGSGSSQSSRYGQQ------GSGSGQSPSR 662

Query: 897  GR--SLFQH-----RHGN-THYSSTDTGTLTITAPTRGGSLFQHRHGEAH---YSSTDTG 945
            GR  S F H     +HG+ + +SS++    +++  + G   F H+ G      YS   +G
Sbjct: 663  GRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSG---FGHKSGSGQSSGYSQHGSG 719

Query: 946  TPTNP-----APTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRP 1000
            +  +          G+     +HG +   S+  G +HG   + S+  G         G  
Sbjct: 720  SSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYG-QHGSGSHQSSGHGR---QGSGSGHS 775

Query: 1001 LFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRSLFQHQCGDVHNSSTDAG 1060
              + RHG +   S+  G +HG     S+  G     +  Q     QH+ G     S    
Sbjct: 776  PSRVRHGSSSGHSSSHG-QHGSGTSCSSSCGHYESGSG-QASGFGQHESGSGQGYSQHGS 833

Query: 1061 TLTIPAVTRGRSLLQHRHGAPTWGRS 1086
                     G    Q RHG+ T G+S
Sbjct: 834  -------ASGHFSSQGRHGS-TSGQS 851



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 104/455 (22%), Positives = 158/455 (34%), Gaps = 66/455 (14%)

Query: 590  FQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLF-QHRHGDAHNSSTDTG 648
            F  QH      S+  G ++ D+H SS   G     + +   P + QH  G   +SS DT 
Sbjct: 165  FSGQHNSYSGQSSSYGEQNSDSHQSS---GRGQCGSGSGQSPNYGQHGSGSGQSSSNDTH 221

Query: 649  TLTIAARTQGRPLFQHRHGDAH---YSSTDTGTLTIPAPTRGRSLFQHRHGAPIWGRSLF 705
                +   Q     QH+        YS   +G+        G S    +HG+   G+S  
Sbjct: 222  G---SGSGQSSGFSQHKSSSGQSSGYSQHGSGS--------GHSSGYGQHGSRS-GQSSR 269

Query: 706  QHRHGDAHYSSTDTGHRHGDAHYSS-----TDVGTLTIPAPTR-----GRSLFQHQHGDV 755
              RH  +  SS+  G +HG     S        G+   P+  R     G S    QHG  
Sbjct: 270  GERHRSSSGSSSSYG-QHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSG 328

Query: 756  HYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGTLTIPAPTQ 815
               S  RG       +    T          G+S    +HG     S+  G       T 
Sbjct: 329  SSYSYSRGHY----ESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQ---HGSTS 381

Query: 816  GRSLFQHQHGDAHYSSTDTGTLTIAA-PTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYCS 874
            G++    QHG +   S+  G    A+  + GR   QH  G+   G+S    + G     S
Sbjct: 382  GQASSSGQHGSSSRQSSSYGQHESASRHSSGRG--QHSSGS---GQSPGHGQRGSGSGQS 436

Query: 875  NDTGTHTIPAPTGTLTIP--APTRGRSLFQHRHGNTHYSSTDTGTLTITAPTRGGSLFQH 932
              +G H       + + P  + +   S F H   ++ +SS  T               QH
Sbjct: 437  PSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYT---------------QH 481

Query: 933  RHGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTI 992
              G  H S        +   ++G          + Y    +G R    H +    G+   
Sbjct: 482  GSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGH-SRHGSGSGQS 540

Query: 993  PAPIQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTS 1027
            P+P +GR    H  G +  SS+   H +G    +S
Sbjct: 541  PSPSRGR----HESG-SRQSSSYGPHGYGSGRSSS 570


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 180/839 (21%), Positives = 290/839 (34%), Gaps = 169/839 (20%)

Query: 287  SHHSDTRALPTDTGTLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLT 346
            S H  +    TD+GT      +   D+G        RG S  Q    + H   +DT +++
Sbjct: 1683 SRHQQSADSSTDSGTGRRQDSSVVGDSG-------NRGSSGSQASDSEGHSEESDTQSVS 1735

Query: 347  IPAP-----------TRGTD------MGTLTIPAPTRDTDPGTLTIPAPTWG---RSLFQ 386
                           TRG         G+      T +          P+ G   RS  +
Sbjct: 1736 AHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHE 1795

Query: 387  HXHGDAHYSSTDTGTLTI---PAPTRG--------RSLFQHXHGDAHYSSTNT------- 428
                 + +S++  G  TI   P  +RG        +S+    H  +H+S T +       
Sbjct: 1796 QARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVS 1855

Query: 429  -----GRSLFQHRHGEAHYS--STDKGHRHRDAHYSSTDTGTLTI-PAPTQGAHYSSTDT 480
                  RS+ +    E      S   G RH +A   +  +    +    + G   S    
Sbjct: 1856 RGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQG 1915

Query: 481  GTLTIAAPTRG----TDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAH 536
             +++  + ++G    ++ W  +      G +  Q R G  H  S    R+     HG + 
Sbjct: 1916 SSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRA----GHGHSA 1971

Query: 537  YSSIDAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGD 596
             SS  +GT    + +RG   SS +                Q R  A  R  S  Q Q  D
Sbjct: 1972 DSSRQSGTRHTESSSRGQAASSHE----------------QARSSAGERHGSHHQLQSAD 2015

Query: 597  THYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAART 656
               SS  +G  HG A  +  D+G          R     +  D+   S D+ T +++A+ 
Sbjct: 2016 ---SSRHSGIGHGQASSAVRDSGH---------RGYSGSQASDSEGHSEDSDTQSVSAQG 2063

Query: 657  QGRPLFQHR----HGDAHYSSTDTGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDA 712
            +  P  Q       G +  SS  +G+      T  +S   H   AP  G      R G +
Sbjct: 2064 KAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGG-----RQG-S 2117

Query: 713  HYSSTDTGHRHGDAHYSSTDVGTLTI---PAPTRGRSLFQHQH---------GDVHYSST 760
            HY       RH     S++  G  TI   P P+RG     HQ          G  H  +T
Sbjct: 2118 HYDQAQDSSRH-----SASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTT 2172

Query: 761  DRGMLTIPAPTRGTDTGTLTIPALTW--------GRSLLQHRHGDAHYCSTDMGTLTIPA 812
             +G       +RG  +G+ +    T+         R    H H  + +  +   +L    
Sbjct: 2173 SQGRSDA---SRG-QSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQG 2228

Query: 813  PT--------QGRSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQ 864
             +        +G S+ Q    + H   ++  + + +    G +  Q + G+    RS  +
Sbjct: 2229 QSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGS-RHPRSHHE 2287

Query: 865  HR--HGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITA 922
             R  HG +   S  +GTH     +G     +  + RS    RHG+ H  S D+       
Sbjct: 2288 DRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADS------- 2340

Query: 923  PTRGGSLFQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDT----GHRHG 978
             +R   +    HG+A  +  D+G        +G    Q    + H   +DT     H   
Sbjct: 2341 -SRHSGI---GHGQASSAVRDSG-------HRGSSGSQASDSEGHSEDSDTQSVSAHGQA 2389

Query: 979  DAHYTSTDMGTLTIPAPIQGRP---LFQ---HRHGDAHY--SSTDTGHRHGDAHYTSTD 1029
              H  S    T    A   GR    L+Q   H   ++ +  + T TG R G  H  + D
Sbjct: 2390 GPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARD 2448



 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 154/753 (20%), Positives = 230/753 (30%), Gaps = 164/753 (21%)

Query: 389  HGDAHYSSTDTGTLTIPAPTRGRSLFQHX---------HGDAHYSSTNTGRSLFQHRHGE 439
            HG +  SS  +GT      + G++   H          HG  H   +          HG+
Sbjct: 670  HGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQ 729

Query: 440  AHYSSTDKGHRHR------DAHYSSTDTGTLTIPAPTQGAHYS--------------STD 479
            A  +  D GHR        D+   S D+ T ++    Q  H+               S  
Sbjct: 730  ASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRR 789

Query: 480  TGTLTIAAPTR----GTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQH----- 530
            +G+      T      +  W      + +G    Q R    H  S D   ++  H     
Sbjct: 790  SGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSR 849

Query: 531  --QHGDAHYSSIDAGTLTIPAPTRGAHYSST-----------DTGTLTIAAPTR------ 571
              + G  H  S+D    +      G+H+S T            +G+ + +  TR      
Sbjct: 850  RGRQGSHHEQSVDRSGHS------GSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSR 903

Query: 572  -GCSLFQHRHGAPTRGCSLFQH-QHGDTHYSSTDTGHRHG---------DAHYSSTDTGT 620
             G      RH   +    + +H Q G      + T  R G         + H   ++  +
Sbjct: 904  DGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWS 963

Query: 621  LTIAARTRGRPLFQHRHGDAH------------------------NSSTDTGTLTIAART 656
             + +   RG    Q RHG  H                        ++ T +G    ++  
Sbjct: 964  GSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHE 1023

Query: 657  QGRPLFQHRHGDAHYSSTDTGTLT-IPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYS 715
            Q R     RHG  H  S D+   + IP      ++    H    WG S  Q    + H  
Sbjct: 1024 QARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGH----WGSSGSQASDSEGHSE 1079

Query: 716  STDT----GHRHGDAHYSSTDVGTLTIPAPTRGRS-LFQHQHGDVHYSSTDRGMLTIPAP 770
             +DT    GH     H  S             GRS  F +Q      S +  G       
Sbjct: 1080 ESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTG 1139

Query: 771  TR---------------GTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDM----GTLTIP 811
             R                +  G  TI A    R     R G  H  S D     G+    
Sbjct: 1140 RRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRR--GGRQGSHHEQSVDRSGHSGSHHSH 1197

Query: 812  APTQGRSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHGDTH 871
              +QGRS   H    +  +S  T     +      S  +H H A +W  S    + G   
Sbjct: 1198 TTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRH-HEAASWADSSRHSQVGQEQ 1256

Query: 872  YCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITAPTRGGSLFQ 931
               + T  H               +G S+ Q      H  S D+  L+       GS  +
Sbjct: 1257 SSGSRTSRH---------------QGSSVSQDSDSERH--SDDSERLS-------GSASR 1292

Query: 932  HRHGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLT 991
            + HG +   S D             P F      +H  S D+  + G  H  S+  G   
Sbjct: 1293 NHHGSSREQSRDGSR---------HPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQ-A 1342

Query: 992  IPAPIQGRPLFQHRHGDAHYSSTDTGHRHGDAH 1024
            + +  Q R     RHG  H  S D+    G  H
Sbjct: 1343 VSSHEQARSSPGERHGSRHQQSADSSRHSGIGH 1375



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 220/1064 (20%), Positives = 335/1064 (31%), Gaps = 214/1064 (20%)

Query: 96   HTFQGKVDAKPPRPGLAAGAMELQELSVLGHT------GAPASRGQLGSAALSAHCPAVH 149
            H+  G+  +  PR     G+   Q+    GH+         ASR   GSA   +   + H
Sbjct: 2222 HSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRH 2281

Query: 150  PSALIYTVPALQLHAGGSGGSGTAFDSSRLITLQLRWLPEPVSVACPPEQRKSVDGPWSQ 209
            P +          H     G G + +SSR               A   EQ +S  G    
Sbjct: 2282 PRS----------HHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHG 2331

Query: 210  S---RAIFLQRRLGLAVRRVSGRVRVFAK-------------HSRDARVRIRGVTVVGAA 253
            S   ++    R  G+   + S  VR                 HS D+       T   +A
Sbjct: 2332 SHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSD------TQSVSA 2385

Query: 254  QGSVATHSWEAKDGPRATGPAQPKIQARFLLLQSHHSDTRALPTDTGTLTIPAPTRGSDT 313
             G    H    ++  R     +      FL   S H  + +    TGT T      G   
Sbjct: 2386 HGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTST------GGRQ 2439

Query: 314  GMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTI---PAPTRGTDMGTLTIPAPTRDTDP 370
            G           S  +       +S++  G  TI   P  + G   G+       R    
Sbjct: 2440 G-----------SHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHS 2488

Query: 371  GTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGR 430
            G+      + GRS   H H  +  +S  T           R+  Q   G  H  S     
Sbjct: 2489 GSHHSHTTSQGRSDASHGHSGSRSASRQT-----------RNDEQSGDGSRHSGS----- 2532

Query: 431  SLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTR 490
                 RH EA   +   GH         +  G      P    ++ S+ +        + 
Sbjct: 2533 -----RHHEASSRADSSGH---------SQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSE 2578

Query: 491  GTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDA-HYSSIDAGTLTIPA 549
             ++ W           S  ++ HG A     D  R    HQ   A H  S D        
Sbjct: 2579 DSERW---------SGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSAD-------- 2621

Query: 550  PTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHG 609
                   SS  +GT      + G +   H     + G      +HG  H  S D+    G
Sbjct: 2622 -------SSRQSGTRHTQTSSGGQAASSHEQARSSAG-----ERHGSHHQQSADSSRHSG 2669

Query: 610  DAHYSSTDTGTLTIAARTRG-RPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQHRHGD 668
              H      G  + A R  G R     +  D    S D+ T +++A  Q     Q     
Sbjct: 2670 IGH------GQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQES 2723

Query: 669  AHYSSTDT----GTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHRHG 724
            A   S +T    G+      T  +S  +  HG   W     + R G  H  + D+     
Sbjct: 2724 ARGRSGETSGHSGSFLYQVSTHEQS--ESSHG---WTGPSTRGRQGSRHEQAQDS----- 2773

Query: 725  DAHYSSTDVGTLTI---PAPTRG-RSLFQHQH--------GDVHYSSTDRGMLTIPAPTR 772
             + +S++  G  TI   P  +RG R  + H+H        G  H  +T +G         
Sbjct: 2774 -SRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQS 2832

Query: 773  GTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGTLTIPAPTQGRS------------LF 820
            G+ + + T           +H     H  ST           QG+S            + 
Sbjct: 2833 GSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVS 2892

Query: 821  QHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHR--HGDTHYCSNDTG 878
            Q    + H   ++  + + +    G +  Q + G+    RS  + R  HG +   S  +G
Sbjct: 2893 QDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGS-RHPRSHQEDRAGHGHSADSSRQSG 2951

Query: 879  THTIPAPTGTLTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITAPTRGGSLFQHRHGEAH 938
            T      +G     +  + RS    RHG+ H  S D+        +R   +    HG+A 
Sbjct: 2952 TRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS--------SRHSGI---GHGQAS 3000

Query: 939  YSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQG 998
             +  D+G               HR      +S + GH        S D  T ++ A  Q 
Sbjct: 3001 SAVRDSG---------------HRGYSGSQASDNEGH--------SEDSDTQSVSAHGQA 3037

Query: 999  RPLFQHRHGDAHYSSTDTGHRHG------DAHYTSTDMGTLTIPAPIQGRSLFQHQCG-- 1050
                Q     A   S +T    G        H  S      T P+  +GR   +H+    
Sbjct: 3038 GSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPS-TRGRQGSRHEQAQD 3096

Query: 1051 DVHNSSTDAGTLTI---PAVTR-GRSLLQHRHGAPTWGRSLFQH 1090
               +S++  G  TI   P  +R GR    H H   + G S   H
Sbjct: 3097 SSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHH 3140



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 168/839 (20%), Positives = 274/839 (32%), Gaps = 124/839 (14%)

Query: 237  SRDARVRIRGVTVVGAAQG-SVATHSWEAKDGPRATGPAQPKIQARFLLLQSHHSDTRAL 295
            SR +R +   V+    ++G S  +  W         G AQ + +      +SHH D RA 
Sbjct: 936  SRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHED-RAG 994

Query: 296  PTDTGTLTIPAPTRGSDT--GMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRG 353
               +   +  + T  ++T  G     +  +  S    RHG  H  S D+        +R 
Sbjct: 995  HGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADS--------SRH 1046

Query: 354  TDMGTLTIPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSL 413
            + +      +  RD+           WG S  Q    + H   +DT +++      G   
Sbjct: 1047 SGIPRRQASSAVRDSGH---------WGSSGSQASDSEGHSEESDTQSVSGHGQD-GPHQ 1096

Query: 414  FQHXHGDAHYSSTNTGRS---LFQ---HRHGEAHY--SSTDKGHRHRDAHYSSTDTGTLT 465
              H      +S   +GRS   ++Q   H   E+ +  + T  G R    H  + D+    
Sbjct: 1097 QSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDS---- 1152

Query: 466  IPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRH---------GDA 516
                   + +S++  G  TI A            P   RG     H           G  
Sbjct: 1153 -------SRHSASQEGQDTIRAH-----------PGSRRGGRQGSHHEQSVDRSGHSGSH 1194

Query: 517  HYCSTDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLF 576
            H  +T  GRS     HG +   S    T        G+ +S +                 
Sbjct: 1195 HSHTTSQGRS--DASHGQSGSRSASRQTRKDKQSGDGSRHSGS----------------- 1235

Query: 577  QHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHR 636
               H A +   S    Q G    S + T    G +    +D+   +  +        ++ 
Sbjct: 1236 -RHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNH 1294

Query: 637  HGDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAHYSSTDTGTLTIPAPTRGRSLFQHRHG 696
            HG +   S D G+       + R      HG +  SS  +GT    + + G+++  H   
Sbjct: 1295 HGSSREQSRD-GSRHPGFHQEDRA----SHGHSADSSRQSGTHHTESSSHGQAVSSHEQA 1349

Query: 697  APIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPAPTRGRSLFQHQHGDVH 756
                 RS    RHG  H  S D+    G  H  ++        +  RG S  Q  + + H
Sbjct: 1350 -----RSSPGERHGSRHQQSADSSRHSGIGHRQASSA---VRDSGHRGSSGSQVTNSEGH 1401

Query: 757  YSSTDRGMLTIPAPT----RGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGTLTIPA 812
               +D   ++         +            + GRS        +H  S      T P+
Sbjct: 1402 SEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPS 1461

Query: 813  PTQGRSLFQHQHG--DAHYSSTDTGTLTI----AAPTRGRSLLQHQHGAPTWGRSQFQHR 866
             T GR   +H+     + +S++  G  TI     +   GR    H+      G S + H 
Sbjct: 1462 -TGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHS 1520

Query: 867  HGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGNTHYSSTDTGTL-------- 918
            H      S+ +   + P      T      G    +H     H  ST  G+         
Sbjct: 1521 HTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGS-RHSGSRHHEPSTRAGSSRHSQVGQG 1579

Query: 919  ----TITAPTRGGSLFQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAH-YSSTDT 973
                + T+  +G S+ Q R  E H   ++  + +      G    Q RHG  +  S  + 
Sbjct: 1580 ESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQED 1639

Query: 974  GHRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGT 1032
               HG +  +S   GT        G+            + +  G RHG  H  S D  T
Sbjct: 1640 RASHGHSAESSRQSGTRHAETSSGGQAASSQEQ-----ARSSPGERHGSRHQQSADSST 1693



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 196/954 (20%), Positives = 333/954 (34%), Gaps = 170/954 (17%)

Query: 223  VRRVSGRVRVFAKHSRDARVRIRGVTVVGAAQG-SVATHSWEAKDGPRATGPAQPKIQAR 281
            + R S  V+  ++ SR +R +   V+    ++G S  +  W         G AQ +++  
Sbjct: 2867 ISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDG 2926

Query: 282  FLLLQSHHSDTRALPTDTGTLTIPAPTRGSDT--GMLTVPATTRGCSLFQHRHGDDHYSS 339
                +SH  D RA    +   +  + TR + T  G     +  +  S    RHG  H  S
Sbjct: 2927 SRHPRSHQED-RAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQS 2985

Query: 340  TDTGTLTIPAPTRGTDMGTLTIPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDT 399
             D+        +R + +G     +  RD+            G S  Q    + H   +DT
Sbjct: 2986 ADS--------SRHSGIGHGQASSAVRDSGHR---------GYSGSQASDNEGHSEDSDT 3028

Query: 400  GTLTI--PAPTRGRSLFQHXHGDAHYSSTNTGRSLFQ---HRHGEAHYSSTD------KG 448
             +++    A +  +S  +   G +  +S ++G  L+Q   H   E+ +  T       +G
Sbjct: 3029 QSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQG 3088

Query: 449  HRHRDAH----YSSTDTGTLTI---PAPTQGA-----HYSSTDTGTLTIAAPTRGTDMWM 496
             RH  A     +S++  G  TI   P  ++G      H  S D+   + +  +  T    
Sbjct: 3089 SRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGR 3148

Query: 497  LTIPALTRG-RSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTRGAH 555
                    G RS  +    +    S D  R  +   H  + ++ I   +  +   + G+ 
Sbjct: 3149 SDASRGQSGSRSASRTTRNEEQ--SGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSR 3206

Query: 556  YSSTDTGTLTIAAPTRGCSLFQHRHGAPT----RGCSLFQHQHGDTH---YSSTDTGHRH 608
             S     +++  + + G S    R         RG    Q +HG  H   +     GH H
Sbjct: 3207 RSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGH 3266

Query: 609  G-------DAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDT--------GTLTIA 653
                       ++ T +G    ++  + R     RHG  H  S D+        G  + A
Sbjct: 3267 SADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSA 3326

Query: 654  ARTQ---GRPLFQHRHGDAHYSSTDTGTLTI-----PAPTRGRSLFQHRHGAPIWGRS-- 703
             R     G    Q    + H   +DT +++      P     +   + R G    GRS  
Sbjct: 3327 VRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRS-GRSGS 3385

Query: 704  -LFQ---HRHGDAHY--SSTDTGHRHGDAH--------YSSTDVGTLTIP----APTRGR 745
             L+Q   H   ++ +  + T TG R G  H        +S++  G  TI     +  RGR
Sbjct: 3386 FLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGR 3445

Query: 746  -------SLFQHQHGDVHYSST--------DRGMLTIPAPTRGTDTGTLTIPALTWGRSL 790
                   S+ +  H   H+S T         RG     + +R T     +       R  
Sbjct: 3446 QGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDG---SRHS 3502

Query: 791  LQHRH------GDAHYCSTDMGTLTIPAPT--QGRSLFQHQHGDAHYSSTDTGTLTIAAP 842
              H H        + +  +  G    P  +  QG S+ Q      H   ++  + + +  
Sbjct: 3503 WSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRN 3562

Query: 843  TRGRSLLQHQHGA--PTWGRSQFQHRHGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSL 900
             RG +  Q + G+  PT    + +  HG +   S  +GTH     +G     +  + RS 
Sbjct: 3563 HRGSAQEQSRDGSRHPT-SHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSS 3621

Query: 901  FQHRHGNTHYSSTDT-----------GTLTITAPTRGGSLFQHRHGEAHYSSTDTGT--- 946
               RHG+ H  S D+            +    +  RG S  Q    E H   +DT +   
Sbjct: 3622 AGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSA 3681

Query: 947  --------PTNPAPTQGRP----------LFQ---HRHGDAHY--SSTDTGHRHGDAHYT 983
                     ++   T+GR           L+Q   H   ++ +  +   TG R G  H  
Sbjct: 3682 HGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQ 3741

Query: 984  STDMGTLTIPA----PIQGRPLFQH--RHGDAHYSSTDTGHRHGDAHYTSTDMG 1031
            + D    +        I+G P  +   R G  H  S D     G  H  +T  G
Sbjct: 3742 ARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQG 3795



 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 157/746 (21%), Positives = 247/746 (33%), Gaps = 153/746 (20%)

Query: 424  SSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTL 483
            S  + G    Q RHG  H  S    H  R  H  S D    +      G  ++ T +G  
Sbjct: 3236 SRNHRGSVQEQSRHGSRHPRSH---HEDRAGHGHSADRSRQS------GTRHAETSSGGQ 3286

Query: 484  TIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGR--SLLQHQHGDAHYSSID 541
              ++  +               RS    RHG  H  S D  R   + + Q   A   S  
Sbjct: 3287 AASSHEQA--------------RSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRH 3332

Query: 542  AGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTR--------GCSLFQ-- 591
             G+    A     H   +DT +++      G     H+  A  R        G  L+Q  
Sbjct: 3333 WGSSGSQASDSEGHSEESDTQSVS-GHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVS 3391

Query: 592  -HQHGDTHY--SSTDTGHRHGDAHYSSTDTGTLTIAAR----TRGRPLFQHR-------- 636
             H+  ++ +  + T TG R G  H  + D+   + +       RG P    R        
Sbjct: 3392 THEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYE 3451

Query: 637  -------HGDAHNSSTDTGTLTIAARTQG-------------------RPLFQHRH---- 666
                   H  +H+S T +   + A+R Q                    R  + H H    
Sbjct: 3452 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEAST 3511

Query: 667  --GDAHYSSTDTGTLTIPAPTR--GRSLFQ------HRHGAPIWGRSLFQHRHGDAHYSS 716
                + +S +  G    P  +R  G S+ Q      H   +  W  S  ++  G A   S
Sbjct: 3512 QADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQS 3571

Query: 717  TDTGHRHGDAHY-----------SSTDVGTLTIPAPTRGRSLFQHQ---------HGDVH 756
             D G RH  +H+           SS   GT      + G++   H+         HG  H
Sbjct: 3572 RD-GSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHH 3630

Query: 757  YSSTDR----GMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGTLTIPA 812
              S D     G+    A +   D+G         G S  Q    + H  S D  T ++ A
Sbjct: 3631 QQSADSSRHSGIGHGQASSAVRDSGHR-------GSSGSQASDSEGH--SEDSDTQSVSA 3681

Query: 813  PTQ-GRSLFQHQH---GDAHYSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHG 868
              Q G     HQ    G +   S  +G+      T  +S   H    P+ G      R G
Sbjct: 3682 HGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGG-----RQG 3736

Query: 869  DTHYCSNDTGTHTIPAPTGTLTI---PAPTRG--------RSLFQHRHGNTHYSSTDTGT 917
              H  + D+  H+  +  G  TI   P   RG        +S+ +  H  +H+S T +  
Sbjct: 3737 SRHEQARDSSRHSA-SQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQG 3795

Query: 918  LTITAPTRGGSLFQHRHGEAHYSSTD----TGTPTNPAPTQGRPLFQHRHGDAHYSSTDT 973
             +  +  + GS    R       S D    +G+  + A TQ       + G    + +  
Sbjct: 3796 RSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRR 3855

Query: 974  GHRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTL 1033
              R G +    +D       +  +     ++ HG +   S D     G +H    D  + 
Sbjct: 3856 SRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSH---RDTASH 3912

Query: 1034 TIPAPIQGRSLFQHQCGDVHNSSTDA 1059
               +P+Q  S    + G   + S D+
Sbjct: 3913 VQSSPVQSDSSTAKEHGHFSSLSQDS 3938



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 181/874 (20%), Positives = 280/874 (32%), Gaps = 213/874 (24%)

Query: 252  AAQGSVATHSWEAKDGPRATGPAQPKIQARFLLLQSHHSDTRALPTDTGTLTIPAPTRGS 311
            +A G    H    K+  R            FL   S H  + +    T      AP+ G 
Sbjct: 1411 SAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQT------APSTGG 1464

Query: 312  DTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTI---PAPTRGTDMGTLTIPAPTRDT 368
              G           S  +       +S++  G  TI   P  +RG   G+    +  R  
Sbjct: 1465 RQG-----------SRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRS- 1512

Query: 369  DPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNT 428
                        G S + H H             T P   +GRS   H       +S  T
Sbjct: 1513 ------------GHSGYHHSH-------------TTP---QGRSDASHGQSGPRSASRQT 1544

Query: 429  GRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAP 488
             R+  Q   G  H      G RH   H  ST  G+       QG    S  T     ++ 
Sbjct: 1545 -RNEEQSGDGSRH-----SGSRH---HEPSTRAGSSRHSQVGQGESAGSK-TSRRQGSSV 1594

Query: 489  TRGTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHYSSIDAGTLTIP 548
            ++  D    +  +  R  S  ++ +G A   S    R+   HQ   A +           
Sbjct: 1595 SQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGH--------- 1645

Query: 549  APTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRH 608
                 +  SS  +GT               RH   + G      Q      + +  G RH
Sbjct: 1646 -----SAESSRQSGT---------------RHAETSSGGQAASSQE----QARSSPGERH 1681

Query: 609  GDAHY----SSTDTGT-----LTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGR 659
            G  H     SSTD+GT      ++   +  R     +  D+   S ++ T +++A  Q  
Sbjct: 1682 GSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAG 1741

Query: 660  PLFQHRHGDAHYSSTDTGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDT 719
            P     H  +H  S           TRG+S    R G           R G   Y  +  
Sbjct: 1742 P-----HQQSHQES-----------TRGQS--GERSG-----------RSGSFLYQVST- 1771

Query: 720  GHRHGDAHYSSTDVGTLTIPAPTRGRSLFQHQHGDVHYSSTDRGMLTI---PAPTRGTDT 776
             H   ++ +  T   T       R RS  +       +S++  G  TI   P  +RG   
Sbjct: 1772 -HEQSESAHGRTGPST-----GGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQ 1825

Query: 777  GTLTIPALTWGRSLLQHRHGDAHYCST-----------DMGTLTIPAPTQGRSLFQHQHG 825
            G+       + +S+    H  +H+  T             G+ ++   T+     Q   G
Sbjct: 1826 GS------HYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEK--QSGDG 1877

Query: 826  DAHYSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYCSNDTGTHTIPAP 885
              H  S      + A  +R   + Q Q   P   R+Q     G +    +D+  H+  + 
Sbjct: 1878 SRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQ-----GSSVSQDSDSQGHSEDSE 1932

Query: 886  TGTLTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITAPTRGGSLFQHRHGEAHYSSTDTG 945
              + +      G +  Q R G+ H  S            R G      HG +  SS  +G
Sbjct: 1933 RWSGSASRNHLGSAWEQSRDGSRHPGSHH--------EDRAG------HGHSADSSRQSG 1978

Query: 946  TPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRPLFQHR 1005
            T    + ++G+    H       + +  G RHG  H              +Q     +H 
Sbjct: 1979 TRHTESSSRGQAASSHEQ-----ARSSAGERHGSHH-------------QLQSADSSRHS 2020

Query: 1006 ---HGDAHYSSTDTGHR------HGDAHYTSTDMGTLTIPAPIQGRSLFQHQC------G 1050
               HG A  +  D+GHR        D+   S D  T ++ A  QG++    Q       G
Sbjct: 2021 GIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSA--QGKAGPHQQSHKESARG 2078

Query: 1051 DVHNSSTDAGTLTIPAVTRGRSLLQHRHGAPTWG 1084
                SS  +G+      T  +S   H   AP+ G
Sbjct: 2079 QSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTG 2112



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 119/556 (21%), Positives = 185/556 (33%), Gaps = 138/556 (24%)

Query: 504  RGRSLFQHRHGDAHYCSTDMGR---SLLQHQHGDAHYSSIDAGTLTIPAPTRGAHYSSTD 560
            RG  + Q R  + H  S D  R   S  ++ HG A   S D         +R       D
Sbjct: 293  RGSRVSQDRDSEGH--SEDSERHSGSASRNHHGSAWEQSRDG--------SRHPRSHDED 342

Query: 561  TGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGT 620
              +   +A +   S  +H   + +RG +   H+      + +  G RHG  H  S D+  
Sbjct: 343  RASHGHSADSSRQSGTRHAETS-SRGQTASSHEQ-----ARSSPGERHGSGHQQSADSSR 396

Query: 621  LTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAHYSSTDTGTL- 679
             +   R           G A ++ +D G        +G    Q    + H  ++DT ++ 
Sbjct: 397  HSATGR-----------GQASSAVSDRG-------HRGSSGSQASDSEGHSENSDTQSVS 438

Query: 680  ----------TIPAPTRGRSLFQHRHGAPIWGRSLFQ---HRHGDAHY--SSTDTGHRHG 724
                      +    TRGRS    R G    G SL+Q   H   D+ +  + T TG R G
Sbjct: 439  GHGKAGLRQQSHQESTRGRS--GERSGRS--GSSLYQVSTHEQPDSAHGRTGTSTGGRQG 494

Query: 725  DAHYSSTDVGTLTIPAPTRGRSLFQHQHGDVHYSSTDRGMLTI---PAPTRGTDTGTLTI 781
              H  + D                        +S++  G  TI   P  +RG   G+   
Sbjct: 495  SHHEQARD---------------------SSRHSASQEGQDTIRGHPGSSRGGRQGS--- 530

Query: 782  PALTWGRSLLQHRHGDAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAA 841
                  +S+ +  H  +H+  T          +QGRS   H    +  +S  T       
Sbjct: 531  ---HHEQSVNRSGHSGSHHSHT---------TSQGRSDASHGQSGSRSASRQTRN----- 573

Query: 842  PTRGRSLLQHQHGAPTWGRSQFQHRH-GDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSL 900
                    + Q G  T        RH G  H+ ++     +  +  G      P   R+ 
Sbjct: 574  --------EEQSGDGT--------RHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRN- 616

Query: 901  FQHRHGNTHYSSTDTGTLTITAPTRGGSLFQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQ 960
                 G++    +D+   +  +    GS  ++ HG A   S D             P   
Sbjct: 617  ----QGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSR---------HPRSH 663

Query: 961  HRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGDAHY-----SSTD 1015
            H     H  S D+  + G  H  ++  G     +  Q R     RHG  H      SS  
Sbjct: 664  HEDRAGHGHSADSSRKSGTRHTQNSSSGQ-AASSHEQARSSAGERHGSRHQLQSADSSRH 722

Query: 1016 TGHRHGDAHYTSTDMG 1031
            +G  HG A     D G
Sbjct: 723  SGTGHGQASSAVRDSG 738



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 89/447 (19%), Positives = 146/447 (32%), Gaps = 100/447 (22%)

Query: 381  GRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHRHGEA 440
            G S         H++   +G     +  + RS     HG  H  S ++ R      HG+A
Sbjct: 3589 GHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS-GIGHGQA 3647

Query: 441  HYSSTDKGHRHR------DAHYSSTDTGTLTIPA-----PTQGAHYSSTDTGTLTIAAPT 489
              +  D GHR        D+   S D+ T ++ A     P Q +H  ST  G     +  
Sbjct: 3648 SSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQEST-RGRSAGRSGR 3706

Query: 490  RGTDMWMLTIPAL-----------TRGRSLFQH---RHGDAHYCSTDMGRSLLQH----- 530
             G+ ++ ++               T GR   +H   R    H  S +   ++  H     
Sbjct: 3707 SGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRR 3766

Query: 531  --QHGDAHYSSIDAGTLTIPAPTRGAHYSST-----------DTGTLTIAAPTRGCSLF- 576
              + G  H  S+D    +      G+H+S T            +G+ + +  TR      
Sbjct: 3767 GGRQGSYHEQSVDRSGHS------GSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSG 3820

Query: 577  -------QHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRG 629
                      H A T+  S    Q G    + +    R G +    +D+      +  R 
Sbjct: 3821 DGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRS 3880

Query: 630  RPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAHYSSTDTGTLTIPAPTRGRS 689
                ++ HG +   S D                  RH  + +  T +   + P  +   +
Sbjct: 3881 ESASRNHHGSSREQSRDGS----------------RHPGSSHRDTASHVQSSPVQSDSST 3924

Query: 690  LFQHRHGAPIWGRSLFQ---------HRHGDAHYSSTDTGHRHGDA-------HYSSTDV 733
              +H H + +   S +          H     HY S  T  + G +        Y S D 
Sbjct: 3925 AKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSADY 3984

Query: 734  GTLTIPAPTRGRSLFQH-QHGDVHYSS 759
                      G S F+H QHG V Y+S
Sbjct: 3985 --------DYGESGFRHSQHGSVSYNS 4003



 Score = 37.7 bits (86), Expect = 0.060
 Identities = 42/177 (23%), Positives = 63/177 (35%), Gaps = 18/177 (10%)

Query: 921  TAPTRGGSLFQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGH-RHGD 979
            T   RG  + Q R  E H   ++  + +      G    Q R G  H  S D     HG 
Sbjct: 289  TRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGH 348

Query: 980  AHYTSTDMGTLTIPAPIQGRPLFQH---------RHGDAHYSSTDTGHRHGDAHYTSTDM 1030
            +  +S   GT       +G+    H         RHG  H  S D+      + +++T  
Sbjct: 349  SADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADS------SRHSATGR 402

Query: 1031 GTLTIPAPIQG-RSLFQHQCGDVHNSSTDAGTLTIPAVTRGRSLLQHRHGAPTWGRS 1086
            G  +     +G R     Q  D    S ++ T ++    +   L Q  H   T GRS
Sbjct: 403  GQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKA-GLRQQSHQESTRGRS 458


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 168/755 (22%), Positives = 249/755 (32%), Gaps = 119/755 (15%)

Query: 248  TVVGAAQGSVATHSWEAKDGPRATGPAQ-PKIQARFLLLQSHHSDTRALPTDTGTLTIPA 306
            T +G ++ S   HS      P ATG A  P   A  +L+          PT     T P 
Sbjct: 3184 TTLGRSEESTTVHS-----SPGATGTALFPTRSATSVLVGE--------PT-----TSPI 3225

Query: 307  PTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTI-PAPTRGTDMGTLTIPAPT 365
             +  ++T  L    TT G S          YSS  +   T+ PA T  + +   +  + +
Sbjct: 3226 SSGSTETTALPGSTTTAGLS----EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 3281

Query: 366  RDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSL------FQHXHG 419
            R     T   P  T    + Q     +H S   T T   P  T   SL      F    G
Sbjct: 3282 RPGSTHTTAFPGSTTMPGVSQESTA-SHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPG 3340

Query: 420  DAHYS--STNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSS 477
                +    NT  S         H SST   H       S+T  G  T         + S
Sbjct: 3341 STETTLLPDNTTASGLLEASTPVH-SSTGSPHTTLSPAGSTTRQGESTT--------FQS 3391

Query: 478  TDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHY 537
                  T  AP   T  ++          S     H  A   ST +GRS    +    H 
Sbjct: 3392 WPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS--STTLGRS---EESTTVHS 3446

Query: 538  SSIDAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGDT 597
            S +   T T P+P R       +  T   ++P    ++                      
Sbjct: 3447 SPV--ATATTPSPARSTTSGLVEESTTYHSSPGSTQTM---------------------- 3482

Query: 598  HYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTI--AAR 655
            H+  +DT    G+   +S  + T TI++               H+S   T T     ++ 
Sbjct: 3483 HFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSST 3542

Query: 656  TQGRPLFQHRHGDAHYSSTD-TGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHY 714
            T GR         A +SS D TGT+ +PA +    L      +PI   S+       A  
Sbjct: 3543 TSGRS----EESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM----ETTALP 3594

Query: 715  SSTDT---GHRHGDAHYSSTDVGTLTIPAPTRGRSLFQH------QHGDVHY-----SST 760
             ST T     +    H S     T   PA T    + +       + G  H      S+T
Sbjct: 3595 GSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTT 3654

Query: 761  DRGM----LTIPAPTRGTDTGTLTIPALTWG---RSLLQHRHGDAHYCSTDMGTLTIPAP 813
              G+     T  +    TDT  L     T G    S   H    +   +   G+ T  + 
Sbjct: 3655 TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSF 3714

Query: 814  TQGRSLFQHQHGDAH---YSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHGD- 869
             Q  + F    G  H   +  + T +  + A TR  S         +   S      G+ 
Sbjct: 3715 GQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 3774

Query: 870  THYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGN---THY--SSTDTG-----TLT 919
            T + ++   THT P+P  T T  AP    + +    G+   TH+  SST +G     T+ 
Sbjct: 3775 TAFQTHPASTHTTPSPPSTAT--APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 3832

Query: 920  ITAPTRGGSLFQHRHGEAHYSSTDTGTPTNPAPTQ 954
             ++P   G+     H         T +  +P  T+
Sbjct: 3833 HSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE 3867



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 180/815 (22%), Positives = 269/815 (33%), Gaps = 137/815 (16%)

Query: 248  TVVGAAQGSVATHSWEAKD----GPRATGPAQPKIQARFLLLQSHHSDTRALPTDT---G 300
            T+ G +Q S A+HS          P +T  +    ++         ++T  LP +T   G
Sbjct: 1739 TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASG 1798

Query: 301  TLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDH-YSSTDTGTLTIPAPTRGT----D 355
             L    P   S TG    P TT   +    R G+   + S  +   T+PAP   T    +
Sbjct: 1799 LLEASTPVHSS-TGS---PHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVE 1854

Query: 356  MGTLTIPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQ 415
            + T +  +P+  T     +  + T GRS            S+   T T P+P R  +   
Sbjct: 1855 LSTTSHGSPS-STPTTHFSASSTTLGRS-----EESTTVHSSPVATATTPSPARSTTSGL 1908

Query: 416  HXHGDAHYSSTNTGRSLFQHRHGEAHY--SSTDKGHRHRDAHYSSTDTGTLTIPAPTQGA 473
                 A++SS  + +++        H+  SST  G         S+ T T++ P  T  A
Sbjct: 1909 VEESTAYHSSPGSTQTM--------HFPESSTASGRSEESRTSHSSTTHTISSPPSTTSA 1960

Query: 474  ------HYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGR---SLFQHRHGDAHYCSTDMG 524
                   Y S+   T T   P   T          T GR   S   H   DA        
Sbjct: 1961 LVEEPTSYHSSPGSTATTHFPDSST----------TSGRSEESTASHSSQDATGTIVLPA 2010

Query: 525  RSLLQHQHGDAHYSSIDAG---TLTIPAPT-------RGAHYSSTDTGTLTIAAPTRGCS 574
            RS      G++  S I +G   T  +P  T       +   + S+     T  +P    S
Sbjct: 2011 RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTS 2070

Query: 575  LFQHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYS---STDTGTLTIAARTRGRP 631
                     +       H       ++T    RH    +S   STDT TL  A+ T   P
Sbjct: 2071 SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT-TLLPASTTTSGP 2129

Query: 632  LFQHRHGDAHNSSTDT----GTLTIAARTQGRPLFQHRHGDAH---YSSTDTGTLTIPAP 684
              +     +   STDT    G+ T  +  Q    F    G  H   +  + T +  + A 
Sbjct: 2130 SQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS 2189

Query: 685  TRGRSLFQHRHGAP-------------IWGRS-LFQHRHGDAHYS----STDTGHRHGDA 726
            TR  S      G+P             + G S  FQ      H +    ST T       
Sbjct: 2190 TRVHS----STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEEST 2245

Query: 727  HYSSTDVGTLTIPAPTRGRSLFQHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLTIPALTW 786
             Y  +   T T   P    +    +   + +SS D    T P+    T +G         
Sbjct: 2246 TYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASG-TTPSSAHSTTSGR-------- 2296

Query: 787  GRSLLQHRHGDAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAAPTRGR 846
            G S        +   +T  G+ T P  ++  + F        YSS  + T T+ +P    
Sbjct: 2297 GESTTSRISPGSTEITTLPGSTTTPGLSEASTTF--------YSSPRSPTTTL-SPASMT 2347

Query: 847  SLLQHQHGAPTWGRSQFQHRHGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHG 906
            SL   +    T  RSQ                TH+  +P  T T        +++    G
Sbjct: 2348 SLGVGEES--TTSRSQ-------------PGSTHSTVSPASTTTPGLSEESTTVYSSSPG 2392

Query: 907  NTHYSSTDTGTLTITAPTRG--GSLFQHRHGEAHYS-----STDTGTPTNPAPTQGRPLF 959
            +T    T     T T   RG   + F  R    H +     ST +G         G P  
Sbjct: 2393 ST---ETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAS 2449

Query: 960  QHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPA 994
                  A  ++ D G        +S   GT   PA
Sbjct: 2450 TQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPA 2484



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 193/869 (22%), Positives = 282/869 (32%), Gaps = 149/869 (17%)

Query: 248  TVVGAAQGSVATHSWEAKDGPRATGPAQ-PKIQARFLLLQSHHSDTRALPTDTGTLTIPA 306
            T +G ++ S   HS      P ATG A  P   A  +L+          PT     T P 
Sbjct: 4267 TTLGRSEESTTVHS-----SPGATGTALFPTRSATSVLVGE--------PT-----TSPI 4308

Query: 307  PTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTI-PAPTRGTDMGTLTIPAPT 365
             +  ++T  L    TT G S          YSS  +   T+ PA T  + +   +  + +
Sbjct: 4309 SSGSTETTALPGSTTTAGLS----EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 4364

Query: 366  RDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSL------FQHXHG 419
            R     T   P+ T    + Q     +H S   T T   P  T   SL      F    G
Sbjct: 4365 RPGSMHTTAFPSSTTMPGVSQESTA-SHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPG 4423

Query: 420  DAHYS--STNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSS 477
                +    NT  S         H SST   H       S+T  G  T         + S
Sbjct: 4424 STETTLLPDNTTASGLLEASTPVH-SSTGSPHTTLSPAGSTTRQGESTT--------FQS 4474

Query: 478  TDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHY 537
                  T  AP   T  ++          S     H  A   ST +GRS    +    H 
Sbjct: 4475 WPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS--STTLGRS---EESTTVHS 4529

Query: 538  SSIDAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSL-FQHRHGAPTRGCSLFQHQHGD 596
            S +   T T P+P R       +  T   ++P    ++ F   +    RG          
Sbjct: 4530 SPV--ATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSST 4587

Query: 597  THY----SSTDTGHRHGDAHYSSTDTGTLTI----AARTRGRPLFQHRHGDAHNSSTDTG 648
            TH      ST +        Y S+   T T     ++ T GR         +H+S   TG
Sbjct: 4588 THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR---SEESTASHSSQDATG 4644

Query: 649  TLTIAARTQGRPLFQHRHGDAHYSSTDTG---TLTIPAPTRGRSLFQHR---HGAPIWGR 702
            T+ + AR+    L     G++  S   +G   T  +P  T    L +     H +P    
Sbjct: 4645 TIVLPARSTTSVLL----GESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSP---- 4696

Query: 703  SLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPAPTRGRSLFQHQHGDVHYSS--- 759
            S     H  A  SST  G         S+ V T T P+P R  +    +    ++SS   
Sbjct: 4697 SSTPTTHFSA--SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGS 4754

Query: 760  ----------TDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGTLT 809
                      T  G       +  + T T++ P  T   S L       H     + T  
Sbjct: 4755 TQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST--TSALVEEPTSYHSSPGSIATTH 4812

Query: 810  IP--APTQGRSLFQHQHGDAHYSSTDTG------------------------------TL 837
             P  + T GRS    +   A +SS DT                               TL
Sbjct: 4813 FPESSTTSGRS----EESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTL 4868

Query: 838  TIAAPTRGRS----LLQHQHGAPTWGRSQFQHRHGD-----THYCSNDTGTHTIPAPTGT 888
               A T G S    +L     +P    S             T   S    THT   P  T
Sbjct: 4869 ASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPAST 4928

Query: 889  LTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITAPTRGGSLFQHRHGEAHYSSTDTGTPT 948
             T    ++  + F  + G+T  ++   G++T ++  +  +    + G A  S+    + T
Sbjct: 4929 TT-SGLSQESTTFHSKPGSTE-TTLSPGSITTSSFAQEFTTPHSQPGSA-LSTVSPASTT 4985

Query: 949  NPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGD 1008
             P  ++    F    G    S+  T   H +     +   T     P    P F H    
Sbjct: 4986 VPGLSEESTTFYSSPG----STETTAFSHSNTMSIHSQQST-----PFPDSPGFTHTVLP 5036

Query: 1009 AHYSSTDTGHRHGDAHYTSTDMGTLTIPA 1037
            A  ++TD G      H +S   GT  +PA
Sbjct: 5037 ATLTTTDIGQESTAFHSSSDATGTTPLPA 5065



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 201/907 (22%), Positives = 299/907 (32%), Gaps = 130/907 (14%)

Query: 248  TVVGAAQGSVATHSWEAKD----GPRATGPAQPKIQARFLLLQSHHSDTRALPTDT---G 300
            T+ G +Q S A+HS          P  T P+    ++        ++ T  LP +T   G
Sbjct: 328  TMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSG 387

Query: 301  TLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDH-YSSTDTGTLTIPAPTRGTDMGTL 359
             L    P   S TG    P TT   S      G+   + S  +   T PAP+ GT    +
Sbjct: 388  LLEASTPVHSS-TGS---PHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPS-GTTSAFV 442

Query: 360  TIPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHG 419
             + + T  + P +      +   +   H        S+   T T P P R  +       
Sbjct: 443  KL-STTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEES 501

Query: 420  DAHYSSTNTGRSLFQHRHGEAHY--SSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSS 477
             A++ S  + +++        H+  SST  GH    A +  + T T +    T  A   +
Sbjct: 502  TAYHRSPGSTQTM--------HFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHT 553

Query: 478  TDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHY 537
            +   +L     T   D    TI   +   S   H   DA   +     S      GD+  
Sbjct: 554  SYHSSLGSTETTHFRD--SSTISGRSE-ESKASHSSPDAMATTVLPAGSTPSVLVGDSTP 610

Query: 538  SSIDAG---TLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQH 594
            S I +G   T  +P  T     S   T   +         L      +     S   H  
Sbjct: 611  SPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSR 670

Query: 595  -GDTHY-----SSTDTG-HRHGDAHYSS---TDT----GTLTIAARTRGRPLFQHRHGDA 640
             G TH      S+T  G  +   A +SS   TDT    G+ T ++       F  R G  
Sbjct: 671  PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGST 730

Query: 641  H-----NSSTDTGTLTIAARTQGRPLFQH----------RHGDA-HYSSTDTGTLTIPAP 684
                  +++T +G L  +          H          R G++  + S  +   T PAP
Sbjct: 731  ETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAP 790

Query: 685  TRGRSLFQH----RHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPA 740
                S F       HG+P    S     H  A   ST +G       Y S+   T T+  
Sbjct: 791  PTTTSAFVEPSTTSHGSP----SSIPTTHISAR--STTSGLVEESTTYHSSPGSTQTMHF 844

Query: 741  PTRGRSLFQHQHGDVHYSSTDRGMLTIPAPTRGT------------DTGTLTIP--ALTW 786
            P    +  + +     +SST   + + P+ T                T T   P  + T 
Sbjct: 845  PESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS 904

Query: 787  GRSLLQHRHGDAHYCSTD-MGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAAPTRG 845
            GRS        A + S D  GT+ +PA +   S+   +   +  SS    T  +   T  
Sbjct: 905  GRS----EESTASHSSQDATGTIVLPARST-TSVLLGESTTSPISSGSMETTALPGSTTT 959

Query: 846  RSLLQHQ---HGAPTWGRSQFQHRHGDTHYCSND-TGTHTIPAPTGTLTIPAPTRGRSLF 901
              L +     H +P    +        +   S + T + + P  T T   P  T    L 
Sbjct: 960  PGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGL- 1018

Query: 902  QHRHGNTHYS---STDTGTLTITAPTRGGSLFQHRHGEAHYSSTDTGTPTNPAPT----- 953
              RH  T +S   STDT  L  +  T G S        +H SS  T T  +P  T     
Sbjct: 1019 -SRHSTTSHSSPGSTDTTLLPASTTTSGPS---QESTTSHSSSGSTDTALSPGSTTALSF 1074

Query: 954  -QGRPLFQHRHGDAHY-----SSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHG 1007
             Q    F    G  H      S+T +G         S+     T  +P            
Sbjct: 1075 GQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA----------- 1123

Query: 1008 DAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRSLFQHQCGDVHNSSTDAGTLTIPA- 1066
                SST  G +     + +    T T P+P    +    +    H S     T   PA 
Sbjct: 1124 ----SSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPAS 1179

Query: 1067 -VTRGRS 1072
              T G S
Sbjct: 1180 STTSGHS 1186



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 208/994 (20%), Positives = 329/994 (33%), Gaps = 169/994 (17%)

Query: 11   GTLTPDSLGDAPAAEMTAHRAFSAKELGARVYSRCTALSESLKKSDLGQSVGTGAVRLQD 70
            GT TP SLG     E T   +          Y++ T L ++   S        G +    
Sbjct: 353  GTTTPSSLGP----ESTTFHSSPG-------YTKTTRLPDNTTTS--------GLLEAST 393

Query: 71   QERRELSAPWGTVLMTRALKWKFRHHTFQGKVDAKPPRPGLAAGAMELQELSVLGHTG-- 128
                   +P  T+  + +   +    TFQ    +K   P  +       +LS   H+   
Sbjct: 394  PVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPS 453

Query: 129  -APASRGQLGSAAL--SAHCPAVH--PSALIYTVPALQLHAGGSGGSGTAFDSSRLITLQ 183
              P +     S  L  S     VH  P A   T P  +    G     TA+  S   T Q
Sbjct: 454  STPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGST-Q 512

Query: 184  LRWLPEPVSVACPPEQRKSVDGPWSQSRAIFLQRRLGLAVRRVSGRV-RVFAKHSRDARV 242
                PE  + +   E+  +  G  + +++        LA       +      H RD+  
Sbjct: 513  TMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSS- 571

Query: 243  RIRGVTVVGAAQGSVATHSWEAKDG------PRATGPAQPKIQARFLLLQSHHSDTRALP 296
                 T+ G ++ S A+HS  + D       P  + P+     +    + S   +T ALP
Sbjct: 572  -----TISGRSEESKASHS--SPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALP 624

Query: 297  TDTG-------TLTIPAPTRGSDTGMLTVPATTRGCS---LFQHRHGDDHYSSTDTGTLT 346
              T        + T  +  R  DT  L    T+ G S      H      +++   G+ T
Sbjct: 625  GSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTT 684

Query: 347  IPAPTRGTDMGTLTIPAPTRDT-DPGTLTIPAPTWGRSLFQHXHGDAHYS-----STDTG 400
            +P  ++ +   + + P PT  T  PG+ T  +     + F    G    +     +T +G
Sbjct: 685  MPGLSQEST-ASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASG 743

Query: 401  TLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTD 460
             L    P    +   H       S+T  G S   H    +  SS D     R A    T 
Sbjct: 744  LLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFH----SWPSSKDT----RPA--PPTT 793

Query: 461  TGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYCS 520
            T     P+ T     SS  T  ++  + T G      T  +             D     
Sbjct: 794  TSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESD----- 848

Query: 521  TDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHRH 580
            T  GR       G+   +S  + T TI         S+  T +  +  PT         H
Sbjct: 849  TTSGR-------GEESTTSHSSTTHTIS--------SAPSTTSALVEEPTS-------YH 886

Query: 581  GAPTRGCSLFQHQHGDTHY--SSTDTGH-RHGDAHYSSTD-TGTLTIAARTRGRPLFQHR 636
             +P    +        TH+  SST +G      A +SS D TGT+ + AR+    L    
Sbjct: 887  SSPGSTAT--------THFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLL--- 935

Query: 637  HGDAHNSSTDTGTLTIAAR--TQGRPLFQHRHGDAHYSSTDTGTLTIPAPTRGRSLFQHR 694
             G++  S   +G++   A   +   P    R    H S     T   PA T    + +  
Sbjct: 936  -GESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEE- 993

Query: 695  HGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPAPTRGRSLFQHQHGD 754
                                 ST +  R G  H ++    T T P  +R  +      G 
Sbjct: 994  ---------------------STTSRSRPGSTHTTAFPDSTTT-PGLSRHSTTSHSSPG- 1030

Query: 755  VHYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGTLTIPAPT 814
                STD  +L     T G    + T            H    +   +   G+ T  +  
Sbjct: 1031 ----STDTTLLPASTTTSGPSQESTT-----------SHSSSGSTDTALSPGSTTALSFG 1075

Query: 815  QGRSLFQHQHGDAH---YSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHGD-T 870
            Q  + F    G  H   +  + T +  + A TR  S         +   S      G+ T
Sbjct: 1076 QESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGEST 1135

Query: 871  HYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGN---THY--SSTDTG-----TLTI 920
             + ++   THT P+P  T T  AP    + +    G+   TH+  SST +G     T+  
Sbjct: 1136 AFQTHPASTHTTPSPPSTAT--APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFH 1193

Query: 921  TAPTRGGSLFQHRHGEAHYSSTDTGTPTNPAPTQ 954
            ++P   G+     H         T +  +P  T+
Sbjct: 1194 SSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE 1227



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 154/727 (21%), Positives = 242/727 (33%), Gaps = 100/727 (13%)

Query: 285  LQSHHSDTRALPTDTGTLTIPAPTRGS--------------DTGMLTVPATTRGCSLFQH 330
            L  H + + + P  T T  +PA T  S               T     P +T   S F  
Sbjct: 2101 LSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALS-FGQ 2159

Query: 331  RHGDDHYSSTDTGTLTIPAPTRGTDMGTLTIPAPTRDTDPGTLTIPAPTWGRSLFQHXHG 390
                 H S   T T   P  T  + +   +    +    P T   PA +    L     G
Sbjct: 2160 ESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL----QG 2215

Query: 391  DAH-YSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGH 449
            ++  + +    T T P+P    +         H S  +T  + F         SST  GH
Sbjct: 2216 ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPA-------SSTTSGH 2268

Query: 450  RHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRG-TDMWML----TIPALTR 504
              +   + S+   + T P+    AH +++  G  T +  + G T++  L    T P L+ 
Sbjct: 2269 SEKSTIFHSSPDASGTTPS---SAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSE 2325

Query: 505  GRSLFQHRH-------GDAHYCSTDMGR--SLLQHQHGDAHYSSIDAGTLTIPAPTRGAH 555
              + F             A   S  +G   +  + Q G  H S++   + T P  +  + 
Sbjct: 2326 ASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTH-STVSPASTTTPGLSEEST 2384

Query: 556  --YSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYS-----STDTGHRH 608
              YSS+   T T   P    +    R   PT     F  +   TH +     ST +G   
Sbjct: 2385 TVYSSSPGSTETTVFPRTPTTSV--RGEEPTT----FHSRPASTHTTLFTEDSTTSGLTE 2438

Query: 609  GDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLF-QHRHG 667
                +  +   T T    T              +SS  TGT    AR+    L  +    
Sbjct: 2439 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPS 2498

Query: 668  DAHYSSTDTGTL----TIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHRH 723
                SST+T TL    T P+ +   + F     +P    S        A  +S+      
Sbjct: 2499 RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS-------PATTTSSGVSEES 2551

Query: 724  GDAHYSSTDVGTLTIPAPTRGRSLFQHQHGDVHYS--STDRGMLTIPAPTRGTDTGTLTI 781
              +H       T   P  T    L +H     H S  STD  +L     T G    + T 
Sbjct: 2552 STSHSQPGSTHTTAFPDSTTTPGLSRHSTTS-HSSPGSTDTTLLPASTTTSGPSQESTT- 2609

Query: 782  PALTWGRSLLQHRHGDAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAH---YSSTDTGTLT 838
                       H    +   +   G+ T  +  Q  + F    G  H   +  + T +  
Sbjct: 2610 ----------SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI 2659

Query: 839  IAAPTRGRSLLQHQHGAPTWGRSQFQHRHGD-THYCSNDTGTHTIPAPTGTLTIPAPTRG 897
            + A TR  S         +   S      G+ T + ++   THT P+P  T T  AP   
Sbjct: 2660 VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTAT--APVEE 2717

Query: 898  RSLFQHRHGN---THY--SSTDTG-----TLTITAPTRGGSLFQHRHGEAHYSSTDTGTP 947
             + +    G+   TH+  SST +G     T+  ++P   G+     H         T + 
Sbjct: 2718 STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 2777

Query: 948  TNPAPTQ 954
             +P  T+
Sbjct: 2778 ISPGSTE 2784



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 201/948 (21%), Positives = 288/948 (30%), Gaps = 178/948 (18%)

Query: 248  TVVGAAQGSVATHSWEAKDGPRAT-GPAQ---PKIQARFLLLQSHHSDTRALPTDTGTLT 303
            T  G  + S   HS  +   PR T  PA    P +Q      Q+H + T   P+   T T
Sbjct: 2655 TSSGIVEASTRVHS--STGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTAT 2712

Query: 304  IPAPTR--------GSDTGMLTVPATTRGCS----LFQHRHGDDHYSSTDTGTLTIPAPT 351
             P             + T      +TT G S    +F   H     S T   +       
Sbjct: 2713 APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF---HSSPDASGTTPSSAHSTTSG 2769

Query: 352  RGTDMGTLTIPAPTRDTD-PGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTI-PAP-- 407
            RG    +   P  T  T  PG+ T P  +   + F        YSS  + T T+ PA   
Sbjct: 2770 RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF--------YSSPRSPTTTLSPASMT 2821

Query: 408  --------TRGRSLFQHXHGDAHYSSTNT-GRSLFQHRHGEAHYSSTDKGHRHRDAHYSS 458
                    T  RS     H     +ST T G S          YSS+  G         S
Sbjct: 2822 SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLS----EESTTVYSSSP-GSTETTVFPRS 2876

Query: 459  TDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHY 518
            T T        T  +  +ST T   T  + T G        P    G          A  
Sbjct: 2877 TTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFP----GSPASTQTGLPATL 2932

Query: 519  CSTDMGRSLLQHQHGDAHYSSIDAGTLTIPA------------PTRGAHYSSTDTGTLTI 566
             + D+G             SS   GT   PA            P+R +  SST+T TL  
Sbjct: 2933 TTADLGEESTTFPS-----SSGSTGTTLSPARSTTSGLVGESTPSRLSP-SSTETTTLPG 2986

Query: 567  AAPTRGCS----LFQHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLT 622
            +  T   S     F     +P    S            S+ +  + G  H ++    T T
Sbjct: 2987 SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTT 3046

Query: 623  IAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAHYSSTDTGTLT-- 680
                    P   H    +  ++   G+ T ++  Q    F    GD   +     T+T  
Sbjct: 3047 SGLSQE--PTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSG 3104

Query: 681  ---IPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLT 737
                  PT   +   H    P                SST  G +     + S    + T
Sbjct: 3105 LVEASTPTHSSTGSLHTTLTPA---------------SSTSAGLQEESTTFQSWPSSSDT 3149

Query: 738  IPAPTRGRSLFQHQHGDVHY--SSTDRGMLTIPAPTRGTD------------TGTLTIPA 783
             P+P    +         H   SST     +  + T G              TGT   P 
Sbjct: 3150 TPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPT 3209

Query: 784  LTWGRSLLQHRHGDAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAAPT 843
             +   S+L      +   S    T  +P  T    L   +     YSS  +   T++  +
Sbjct: 3210 RS-ATSVLVGEPTTSPISSGSTETTALPGSTTTAGL--SEKSTTFYSSPRSPDTTLSPAS 3266

Query: 844  RGRSLLQHQHGAPTWGRSQFQHRHGDTHYCS------------NDTGTHTIPAPTGTLTI 891
               S +  +        +    R G TH  +              T +H+ P  T T   
Sbjct: 3267 TTSSGVSEES-------TTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLS 3319

Query: 892  PAPTRGRSL------FQHRHGNTHYS-----STDTGTLTITAPTRGGSLFQH-------- 932
            P  T   SL      F    G+T  +     +T +G L  + P    +   H        
Sbjct: 3320 PGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGS 3379

Query: 933  --RHGEAH-YSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYT------ 983
              R GE+  + S      T PAP      F      +H S + T   H  A  T      
Sbjct: 3380 TTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSE 3439

Query: 984  ------STDMGTLTIPAP--------IQGRPLFQHRHGDA---HYSSTDTGHRHGDAHYT 1026
                  S+ + T T P+P        ++    +    G     H+  +DT    G+   T
Sbjct: 3440 ESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTT 3499

Query: 1027 STDMGTLTIPAPIQGRSLFQHQCGDVHNSSTDAGTLTIP--AVTRGRS 1072
            S    T TI +     S    +    H+S     T   P  + T GRS
Sbjct: 3500 SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS 3547



 Score = 38.9 bits (89), Expect = 0.027
 Identities = 155/731 (21%), Positives = 229/731 (31%), Gaps = 122/731 (16%)

Query: 305  PAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGTDMGTLTIPAP 364
            P     + TG+   PAT     L +       + S+   T T  +P R T  G +    P
Sbjct: 2918 PGSPASTQTGL---PATLTTADLGEE---STTFPSSSGSTGTTLSPARSTTSGLVGESTP 2971

Query: 365  TRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYS 424
            +R +   T T   P    +          Y+S  +   T+   T   S        +H  
Sbjct: 2972 SRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQ 3031

Query: 425  STNTGRSLFQHRHGEAHYSSTDKG--HRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGT 482
              +T  + F         S+T  G       +H S   T     P  T     SS    +
Sbjct: 3032 PGSTHTTAFPD-------STTTSGLSQEPTASHSSQGSTEATLSPGSTTA---SSLGQQS 3081

Query: 483  LTIAAPTRGTDMWMLTIPALTRG---RSLFQHRH-GDAHYCSTDMGRSLLQHQHGDAHYS 538
             T  +    T+  +L    +T G    S   H   G  H   T    +    Q     + 
Sbjct: 3082 TTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQ 3141

Query: 539  SIDAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHR-HGAPTRGCSLFQHQHGDT 597
            S  + + T P+P              T AAP    + +  R    PT            T
Sbjct: 3142 SWPSSSDTTPSPPG------------TTAAPVEVSTTYHSRPSSTPT------------T 3177

Query: 598  HYSSTDT----GHRHGDAHYSSTDTGTLTIAARTRGRPLF-QHRHGDAHNSSTDTGTLTI 652
            H+S++ T           H S   TGT     R+    L  +       + ST+T  L  
Sbjct: 3178 HFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPG 3237

Query: 653  AARTQGRPLFQHRHGDAHYSSTDTGTLTIPAPTRGRSLFQH---RHGAPIWGRSLFQHRH 709
            +  T G      +    + S     T   PA T    + +     H  P          H
Sbjct: 3238 STTTAG---LSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP-------GSTH 3287

Query: 710  GDAHYSST---DTGHRHGDAHYSSTDVGTLTIPAPTRGRSL------FQHQHGDVHY--- 757
              A   ST           +H S     T   P  T   SL      F    G       
Sbjct: 3288 TTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLL 3347

Query: 758  --SSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDA-HYCSTDMGTLTIPAPT 814
              ++T  G+L    P   + TG+   P  T   +    R G++  + S      T PAP 
Sbjct: 3348 PDNTTASGLLEASTPVH-SSTGS---PHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPP 3403

Query: 815  QGRSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHGDTHYCS 874
               S F      +H S + T T   +A             + T GRS+            
Sbjct: 3404 TTTSAFVELSTTSHGSPSSTPTTHFSA------------SSTTLGRSE------------ 3439

Query: 875  NDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITAPTRGGSLFQHRH 934
              T  H+ P  T T   PA +    L +    +T Y S+   T T+  P    +  +   
Sbjct: 3440 ESTTVHSSPVATATTPSPARSTTSGLVEE---STTYHSSPGSTQTMHFPESDTTSGRGEE 3496

Query: 935  GEAHYSSTDTGTPTNPAPTQG---RPLFQHRH----GDAHY--SSTDTGH-RHGDAHYTS 984
                +SST     + P+ T      P   H         H+  SST +G      A ++S
Sbjct: 3497 STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 3556

Query: 985  TD-MGTLTIPA 994
             D  GT+ +PA
Sbjct: 3557 QDATGTIVLPA 3567



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 84/414 (20%), Positives = 138/414 (33%), Gaps = 51/414 (12%)

Query: 248  TVVGAAQGSVATHSWEAKDGPRATGPAQPKIQARFLLLQSHHSDTRALPTDTGTLTIPAP 307
            T  G ++ S   HS      P +T        A    L      T    +   T T P+P
Sbjct: 4681 TTPGLSEKSTTFHS-----SPSSTPTTH--FSASSTTLGRSEESTTVHSSPVATATTPSP 4733

Query: 308  TRGSDTGML---TVPATTRGCSLFQH--------RHGDDHYSSTDTGTLTIPAPTRGTDM 356
             R + +G++   T   ++ G +   H           ++  +S  + T TI +P   T  
Sbjct: 4734 ARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT-- 4791

Query: 357  GTLTIPAPTR-DTDPGTL-TIPAPTWGRSLFQHXHGDAHYSSTDTGTLT-IPA--PTRGR 411
             +  +  PT   + PG++ T   P    +  +     A +SS DT  +T +PA   T GR
Sbjct: 4792 -SALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGR 4850

Query: 412  ----SLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIP 467
                + F    G    +  +T  +          YSS+    R  D   S     + +I 
Sbjct: 4851 IAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSS----RSPDQTLSPASMTSSSIS 4906

Query: 468  APTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYC-------- 519
                  +  +  T T    A T        T   L++  + F  + G             
Sbjct: 4907 GEPTSLYSQAESTHTTAFPAST--------TTSGLSQESTTFHSKPGSTETTLSPGSITT 4958

Query: 520  STDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTR-GAHYSSTDTGTLTIAAPTRGCSLFQH 578
            S+        H    +  S++   + T+P  +     + S+   T T A           
Sbjct: 4959 SSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHS 5018

Query: 579  RHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPL 632
            +   P      F H       ++TD G      H SS  TGT  + AR+    L
Sbjct: 5019 QQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDL 5072


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 141/668 (21%), Positives = 222/668 (33%), Gaps = 73/668 (10%)

Query: 336 HYSSTDTGTLTIPAPTRGTDMGTLTIPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYS 395
           H S     T  +PA +  + +   + P+P       T  +P  T    L +       YS
Sbjct: 71  HSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEK--STTFYS 128

Query: 396 ST---DTGTLTIPAPTRG---RSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGH 449
           S    DT  L     + G    S   H    + +++   G +       E+  S +  G 
Sbjct: 129 SPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGP 188

Query: 450 RHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLF 509
                   ST   +L     T  +   ST+T  L    P   T   +L         +  
Sbjct: 189 TDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLL----PDNTTASGLLEASMPVHSSTRS 244

Query: 510 QHRHGDAHYCSTDMGRSLLQHQHGDAHYSSIDAGTLT--IPAPTRGAHYSSTDTGTLTIA 567
            H        +T  G S   H    +  +     T T     P+  +H S +   T  I+
Sbjct: 245 PHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHIS 304

Query: 568 APTRGCSLFQHRHGAPTRGCSLFQHQHGDT---HYSSTDTGHRHGDAHYSSTDTGTLTIA 624
           A +    L +          + +    G T   H+  +DT    G+   +S  + T TI+
Sbjct: 305 ARSTTSGLVEES--------TTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTIS 356

Query: 625 ARTRGRPLFQHRHGDAHNSSTDTGTLTI--AARTQGRPLFQHRHGDAHYSSTD-TGTLTI 681
           +               H+S   T T     ++ T GR         A +SS D TGT+ +
Sbjct: 357 SAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS----EESTASHSSQDATGTIVL 412

Query: 682 PAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDT---GHRHGDAHYSSTDVGTLTI 738
           PA +    L      +PI   S+       A   ST T     R    H S     T   
Sbjct: 413 PARSTTSVLLGESTTSPISSGSM----ETTALPGSTTTPGLSERSTTFHSSPRSPATTLS 468

Query: 739 PAPTRGRSLFQH------QHGDVHY-----SSTDRGM----LTIPAPTRGTDTGTLTIPA 783
           PA T    + +       + G  H      S+T  G+     T  +    TDT  L    
Sbjct: 469 PASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAST 528

Query: 784 LTWG---RSLLQHRHGDAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAH---YSSTDTGTL 837
            T G    S   H    +   +   G+ T  +  Q  + F    G  H   +  + T + 
Sbjct: 529 TTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSG 588

Query: 838 TIAAPTRGRSLLQHQHGAPTWGRSQFQHRHGD-THYCSNDTGTHTIPAPTGTLTIPAPTR 896
            + A TR  S         +   S      G+ T + ++   THT P+P  T T  AP  
Sbjct: 589 IVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTAT--APVE 646

Query: 897 GRSLFQHRHGN---THY--SSTDTG-----TLTITAPTRGGSLFQHRHGEAHYSSTDTGT 946
             + +    G+   TH+  SST +G     T+  ++P   G+     H         T +
Sbjct: 647 ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTS 706

Query: 947 PTNPAPTQ 954
             +P  T+
Sbjct: 707 RISPGSTE 714



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 52/223 (23%), Positives = 78/223 (34%), Gaps = 35/223 (15%)

Query: 877  TGTHTIPAPTGTLTIPAPTRGRSL------FQHRHGNTHYS-----STDTGTLTITAPTR 925
            T +H+ P PT T   P  T   SL      F  R G+T  +     +T +G L  + P  
Sbjct: 180  TASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVH 239

Query: 926  GGSLFQH----------RHGEAH-YSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTG 974
              +   H          R GE+  + S  +   T PAP      F      +H S +   
Sbjct: 240  SSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIP 299

Query: 975  HRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGDA---HYSSTDTGHRHGDAHYTSTDMG 1031
              H  A  T++ +        ++    +    G     H+  +DT    G+   TS    
Sbjct: 300  TTHISARSTTSGL--------VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSST 351

Query: 1032 TLTIPAPIQGRSLFQHQCGDVHNSSTDAGTLTIP--AVTRGRS 1072
            T TI +     S    +    H+S     T   P  + T GRS
Sbjct: 352  THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS 394



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 137/632 (21%), Positives = 202/632 (31%), Gaps = 111/632 (17%)

Query: 285  LQSHHSDTRALPTDTGTLTIP-APTRGSDTGMLTV-------------PATTRGCSLFQH 330
            L    + +R  P+ T T T+P +PT  S +   T              PATT    + + 
Sbjct: 895  LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE 954

Query: 331  RHGDDHYSSTDTGTLTIPAPTRGTDMGTLTIPAPTRDTDPGTLTIPAPTWGRSLFQHXHG 390
                 H     T T   P  T  +D+      + +          P  T   SL Q    
Sbjct: 955  S-STSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQST- 1012

Query: 391  DAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHR 450
              H S  DT T  +P  T    L +        +ST T  S           SST  G +
Sbjct: 1013 TFHSSPGDTETTLLPDDTITSGLVE--------ASTPTHSSTGSLHTTLTPASSTSAGLQ 1064

Query: 451  HRDAHYSSTDTGTLTIPAP------------TQGAHYSSTDTGTLTIAAPTRGTDMWMLT 498
                 + S  + + T P+P            T  +  SST T   + ++ T G      T
Sbjct: 1065 EESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTT 1124

Query: 499  I---PALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTRGAH 555
            +   P  T G +LF  R             S+L  +   +  SS    T  +P  T  A 
Sbjct: 1125 VHSSPGAT-GTALFPTRSAT----------SVLVGEPTTSPISSGSTETTALPGSTTTAG 1173

Query: 556  YSSTDTGTLTIA-APTRGCSLFQHRHGAPTRGCSLFQHQHGDTHY-----SSTDTG-HRH 608
             S   T   +   +P    S         +   +    + G TH      S+T  G  + 
Sbjct: 1174 LSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQE 1233

Query: 609  GDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQ----- 663
              A +SS  +   T++  +             H+S   T T  +   T    L +     
Sbjct: 1234 STASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPV 1293

Query: 664  -HRHGDAHYSSTDTGTLT-----------------IPAPTRGRSLFQH----RHGAPIWG 701
                G  H + +  G+ T                 +PAP    S F       HG+P   
Sbjct: 1294 HSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSP--- 1350

Query: 702  RSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPAPTRGRSLFQHQHGDVHY---- 757
             S     H  A  SST  G         S+ V T T P+P R  +    +    ++    
Sbjct: 1351 -SSTPTTHFSA--SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPG 1407

Query: 758  ---------SSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGTL 808
                     SST  G       +  + T T++ P  T   S L       H     + T 
Sbjct: 1408 STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST--TSALVEEPTSYHSSPGSIATT 1465

Query: 809  TIP--APTQGRSLFQHQHGDAHYSSTDTGTLT 838
              P  + T GRS    +   A +SS DT  +T
Sbjct: 1466 HFPESSTTSGRS----EESTASHSSPDTNGIT 1493



 Score = 35.0 bits (79), Expect = 0.39
 Identities = 79/387 (20%), Positives = 129/387 (33%), Gaps = 59/387 (15%)

Query: 103  DAKPPRPGLAAGAMELQELSVLGHTGAPASRGQLGSAALSAHCPAVHPSALIYTVPALQL 162
            D  P  PG  A  +E+       +   P+S      +A S        S  +++ P    
Sbjct: 1078 DTTPSPPGTTAAPVEVSTT----YHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP---- 1129

Query: 163  HAGGSGGSGTAFDSSRLITLQLRWLPEPVSVACPPEQRKSVDGPWSQSRAIFLQRRLGLA 222
                 G +GTA   +R  T  L  + EP +        ++   P S + A       GL+
Sbjct: 1130 -----GATGTALFPTRSATSVL--VGEPTTSPISSGSTETTALPGSTTTA-------GLS 1175

Query: 223  VRRVSGRVRVFAKHSRDARVRIRGVTVVGAAQGSVATHSWEAKDGPRATGPAQPKIQARF 282
             +  +      +  S D  +     T  G ++ S  +HS      P +T           
Sbjct: 1176 EKSTTF---YSSPRSPDTTLSPASTTSSGVSEESTTSHS-----RPGSTHTTAFPGSTTM 1227

Query: 283  LLLQSHHSDTRALPTDTGTLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDT 342
              +    + + + P  T T   P  T  S  G    P +T             H S   T
Sbjct: 1228 PGVSQESTASHSSPGSTDTTLSPGSTTASSLG----PESTTF-----------HSSPGST 1272

Query: 343  GTLTIPAPTRGTDMGTLTIPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAH-YSSTDTGT 401
             T  +P  T  + +   + P  +    P T   PA +  R       G++  + S  +  
Sbjct: 1273 ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQ------GESTTFQSWPSSK 1326

Query: 402  LTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDT 461
             T+PAP    S F      +H S ++T  + F         SST  G         S+  
Sbjct: 1327 DTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSA-------SSTTLGRSEESTTVHSSPV 1379

Query: 462  GTLTIPAPTQGAHYSSTDTGTLTIAAP 488
             T T P+P +       +  T   ++P
Sbjct: 1380 ATATTPSPARSTTSGLVEESTAYHSSP 1406



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 57/240 (23%), Positives = 92/240 (38%), Gaps = 32/240 (13%)

Query: 248  TVVGAAQGSVATHSWEAKD----GPRATGPAQPKIQARFLLLQSHHSDTRALPTDT---G 300
            T+ G +Q S A+HS          P +T  +    ++         ++T  LP +T   G
Sbjct: 1226 TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASG 1285

Query: 301  TLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDH-YSSTDTGTLTIPAPTRGT----D 355
             L    P   S TG    P TT   +    R G+   + S  +   T+PAP   T    +
Sbjct: 1286 LLEASTPVHSS-TGS---PHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVE 1341

Query: 356  MGTLTIPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQ 415
            + T +  +P+  T     +  + T GRS            S+   T T P+P R  +   
Sbjct: 1342 LSTTSHGSPS-STPTTHFSASSTTLGRS-----EESTTVHSSPVATATTPSPARSTTSGL 1395

Query: 416  HXHGDAHYSSTNTGRSLFQHRHGEAHY--SSTDKGHRHRDAHYSSTDTGTLTIPAPTQGA 473
                 A++SS  + +++        H+  SST  G         S+ T T++ P  T  A
Sbjct: 1396 VEESTAYHSSPGSTQTM--------HFPESSTASGRSEESRTSHSSTTHTISSPPSTTSA 1447



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 52/236 (22%), Positives = 80/236 (33%), Gaps = 20/236 (8%)

Query: 248  TVVGAAQGSVATHSWEAKDGPRATGPAQPKIQARFLLLQSHHSDTRALP----TDTGTLT 303
            T  G  + S   HS         +       Q      QS  S    +P    T +  + 
Sbjct: 1282 TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVE 1341

Query: 304  IPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGTDMGTLTIPA 363
            +   + GS +   T   +    +L +       +SS    T T P+P R T  G +    
Sbjct: 1342 LSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSP-VATATTPSPARSTTSGLVEEST 1400

Query: 364  PTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHY 423
                +   T T+  P    +  +       +SST   T TI +P    S         H 
Sbjct: 1401 AYHSSPGSTQTMHFPESSTASGRSEESRTSHSST---THTISSPPSTTSALVEEPTSYHS 1457

Query: 424  SSTNTGRSLFQHRHGEAHYSSTDKGHRHRD-AHYSSTDTGTLTIPAPTQGAHYSST 478
            S  +   + F         SST  G      A +SS DT  +T P P   AH++++
Sbjct: 1458 SPGSIATTHFPE-------SSTTSGRSEESTASHSSPDTNGIT-PLP---AHFTTS 1502


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 173/777 (22%), Positives = 231/777 (29%), Gaps = 125/777 (16%)

Query: 292  TRALPTDTGTLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAP- 350
            T   P  T  L   A  R + T      ATTR  +            ST   T+T+P P 
Sbjct: 1276 TAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPA 1335

Query: 351  TRGTDMGTLTIPAPTRDTDPGTLT--------IPAPTWGRSLFQHXHGDAHYSSTDTGTL 402
            T GT     T+P  T    PGT           PA T G +  Q        ++  T T 
Sbjct: 1336 TSGTSP---TLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTR 1392

Query: 403  TIPAPTRGRSLF-QHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDT 461
            T    T  ++    H    A     +TG       H    Y +          H     T
Sbjct: 1393 TTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFST 1452

Query: 462  -----GTLTIPAPTQ-----GAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQH 511
                  T T+  PT       A   S  TGT+      + T     T P +T   S    
Sbjct: 1453 SLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGS-THTAPPITPTTSGTSQ 1511

Query: 512  RHGDAHYCSTDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTRGAHYSSTDTGTLTIAAPTR 571
             H      ST+   + L       H+  +   + T   P   +  + T       A  +R
Sbjct: 1512 AHSS---FSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSR 1568

Query: 572  GCSLFQHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSST--------DTGTLTI 623
                F   H  PT G S F      T  S   T      +H  +T         T  +T 
Sbjct: 1569 PPPPFT-THSPPT-GSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 1626

Query: 624  AARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAHYSSTDTGTLTIPA 683
            +  T   P        A   S  TGT+         P      G  H + T T T     
Sbjct: 1627 STHTVITPTHAQMATSASIHSMPTGTIP-------PPTTLKATGSTHTAPTMTLT----- 1674

Query: 684  PTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPAPTR 743
             T G S             SL  H     H  +T T   +   + +ST  GT  +   T 
Sbjct: 1675 -TSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTST--GTPPMTVTTS 1731

Query: 744  GRSLFQHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCST 803
            G S           + T   + +  + T   +  + +  ++T   +    R   AH  S 
Sbjct: 1732 GTS---QSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSA 1788

Query: 804  DMGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQF 863
                L  P  T             H   T T  ++   P    S         T+     
Sbjct: 1789 TSSRLPTPFTT-------------HSPPTGTTPISSTGPVTATSF----QTTTTYPTPSH 1831

Query: 864  QHRHGDTHYCSNDT-----GTHTIPAPTGTL-------------TIPAPTRGRSLFQHRH 905
             H    TH  S  T      THT+  PT T              TIP PT  ++      
Sbjct: 1832 PHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKAT----- 1886

Query: 906  GNTHYSSTDTGTLTITAPTRGG--------SLFQHRHGEAHYSSTDTGTPTNPAPTQGRP 957
            G+TH +   T T + T+ +           SL  H     H   T T T TN  P     
Sbjct: 1887 GSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTST-TNITP----- 1940

Query: 958  LFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGDAHYSST 1014
                         T TG R   AH TS     L  P      P      G + +SST
Sbjct: 1941 -----------KHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPT-----GSSPFSST 1981



 Score = 37.0 bits (84), Expect = 0.10
 Identities = 141/648 (21%), Positives = 194/648 (29%), Gaps = 69/648 (10%)

Query: 296  PTDTGTLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGTD 355
            PT TGT  +   T G+     +        SL  H     H   T T T +I      T 
Sbjct: 1718 PTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSI--TPNHTS 1775

Query: 356  MGTLTIPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQ 415
             GT T  A T       L  P  T          G    SST   T T    T       
Sbjct: 1776 TGTRTPVAHTTSATSSRLPTPFTT-----HSPPTGTTPISSTGPVTATSFQTTTTYPTPS 1830

Query: 416  HXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHY 475
            H H        +   SL       + ++     H       S     T TIP PT     
Sbjct: 1831 HPHTTLPTHVPSFSTSLVT----PSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKAT 1886

Query: 476  SSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGD- 534
             ST T    +   T GT     +        SL  H     H   T    + +  +H   
Sbjct: 1887 GSTHTAP-PMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTST 1945

Query: 535  ------AHYSSIDAGTLTIP-----APTRGAHYSSTDTGTLTIAAPTRGCSLFQH----- 578
                  AH +S  +  L  P      PT  + +SST   T T    T       H     
Sbjct: 1946 GTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTL 2005

Query: 579  -RHGAPTRGCSLFQHQHG---DTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRP--- 631
              H  P     +    H     TH     +   H     +     TL     T   P   
Sbjct: 2006 PTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMT 2065

Query: 632  LFQHRHGDAHNS-STDTGTLTIAARTQGRPLFQHRHGDAHYSSTD---TGTLTIPAPTRG 687
            +        H+S ST T + +  + +   P        +   +T      + T P  T  
Sbjct: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125

Query: 688  R--SLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPAPTRGR 745
            +  S F     AP    S     H     SS   G     + + S  V + T+ + +   
Sbjct: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVG---TSSSFVSAPVHSTTLSSGSHS- 2181

Query: 746  SLFQHQ-----HGDVHYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHY 800
            SL  H           + S+     TI A    T +   T+ AL    ++       +H 
Sbjct: 2182 SLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHL 2241

Query: 801  CSTDMGTLTIPAPTQGRSLFQHQHGDAHYSSTDTG---TLTIAAPTRG-RSLLQHQHGAP 856
             S+     TI  P+  R+        A  S + T    +LT   PT G  SL     G P
Sbjct: 2242 ASS-----TIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP 2296

Query: 857  TWGRSQFQHRH------GDTHYCSNDTGTH---TIPAPTGTLTIPAPT 895
            T   +    RH        T + ++    H      AP  +L  P PT
Sbjct: 2297 TSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPT 2344



 Score = 32.0 bits (71), Expect = 3.3
 Identities = 56/245 (22%), Positives = 81/245 (33%), Gaps = 21/245 (8%)

Query: 861  SQFQHRHGDTHYCSNDTGTHTIPA-PTGTLTI-PAPTRGRSLFQHRHGNTHYSSTDTGTL 918
            S F      T   S+ + TH     PT T TI P PT  R+     H N+  SS      
Sbjct: 1514 SSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPF 1573

Query: 919  TITAPTRGGSLFQH---RHGEAHYSSTDTGTPTNP---APTQGRPLFQHRHGDAHYSSTD 972
            T  +P  G S F         +  ++T   TP++P    PT   P        + ++   
Sbjct: 1574 TTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIT 1633

Query: 973  TGHRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGT 1032
              H       +   M T TIP P   +       G  H + T T    G +   S+ + T
Sbjct: 1634 PTHAQMATSASIHSMPTGTIPPPTTLKAT-----GSTHTAPTMTLTTSGTSQALSS-LNT 1687

Query: 1033 LTIPAPIQGRSLFQHQCGDVHNSSTD-------AGTLTIPAVTRGRSLLQHRHGAPTWGR 1085
                  +   +   H       S+T+        GT  +   T G S  +          
Sbjct: 1688 AKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTST 1747

Query: 1086 SLFQH 1090
            SL  H
Sbjct: 1748 SLHSH 1752


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 105/466 (22%), Positives = 159/466 (34%), Gaps = 63/466 (13%)

Query: 598  HYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTI--AAR 655
            H+  +DT    G+   +S  + T TI++               H+S   T T     ++ 
Sbjct: 2    HFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSST 61

Query: 656  TQGRPLFQHRHGDAHYSSTD-TGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHY 714
            T GR         A +SS D TGT+ +PA +    L      +PI   S+       A  
Sbjct: 62   TSGRS----EESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM----ETTALP 113

Query: 715  SSTDT---GHRHGDAHYSSTDVGTLTIPAPTRGRSLFQH------QHGDVHY-----SST 760
             ST T     +    H S     T   PA T    + +       + G  H      S+T
Sbjct: 114  GSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTT 173

Query: 761  DRGM----LTIPAPTRGTDTGTLTIPALTWG---RSLLQHRHGDAHYCSTDMGTLTIPAP 813
              G+     T  +    TDT  L     T G    S   H    +   +   G+ T  + 
Sbjct: 174  TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSF 233

Query: 814  TQGRSLFQHQHGDAH---YSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHGD- 869
             Q  + F    G  H   +  + T +  + A TR  S         +   S      G+ 
Sbjct: 234  GQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 293

Query: 870  THYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGN---THY--SSTDTG-----TLT 919
            T + ++   THT P+P  T T  AP    + +    G+   TH+  SST +G     T+ 
Sbjct: 294  TAFQTHPASTHTTPSPPSTAT--APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 351

Query: 920  ITAPTRGGSLFQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTG----- 974
             ++P   G+     H      ST +G     + +  +P     H  A   ST T      
Sbjct: 352  HSSPDASGTTPSSAH------STTSGVSEESSTSHSQP--GSTHTTAFPDSTTTSGLSQE 403

Query: 975  --HRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGDAHYSSTDTGH 1018
                H     T   + T   P      P+       +  SST T H
Sbjct: 404  PTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 449



 Score = 37.0 bits (84), Expect = 0.10
 Identities = 65/312 (20%), Positives = 104/312 (33%), Gaps = 35/312 (11%)

Query: 248 TVVGAAQGSVATHSWEAKDGPRAT-GPAQ---PKIQARFLLLQSHHSDTRALPTDTGTLT 303
           T  G  + S   HS  +   PR T  PA    P +Q      Q+H + T   P+   T T
Sbjct: 257 TSSGIVEASTRVHS--STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTAT 314

Query: 304 IPAPTR--------GSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGTD 355
            P             + T      +TT G     H      + S+   + T P+    T 
Sbjct: 315 APVEESTTYHRSPGSTPTTHFPASSTTSG-----HSEKSTIFHSSPDASGTTPSSAHSTT 369

Query: 356 MGTLTIPAPTRDTDPG---TLTIPAPTWGRSLFQH-XHGDAHYSSTDTGTLTIPAPTRGR 411
            G ++  + T  + PG   T   P  T    L Q      +   ST+    T P+P    
Sbjct: 370 SG-VSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTT 428

Query: 412 SLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQ 471
           +         H   ++T  +     H  A  ++  +       H S   T T  +P  T 
Sbjct: 429 AAPVEVSTTYHSRPSSTPTT-----HFSASSTTLGRSEESTTVHSSPGSTETTALPGSTT 483

Query: 472 GAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRG---RSLFQHRHGDAHYCSTDMGRSLL 528
            A  S   T   T  +  R  D  +      + G    S   H    + + +   G + +
Sbjct: 484 TAGLSEKST---TFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTM 540

Query: 529 QHQHGDAHYSSI 540
             QH  A ++++
Sbjct: 541 PGQHWIATHNTV 552



 Score = 34.3 bits (77), Expect = 0.66
 Identities = 110/520 (21%), Positives = 163/520 (31%), Gaps = 53/520 (10%)

Query: 287 SHHSDTRAL---PTDTGTLTIPAPTRGSDTGMLTVP-----ATTRGCSLFQHRHGDDHYS 338
           SH S T  +   P+ T  L     +  S  G          +TT G S         H S
Sbjct: 19  SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS---EESTASHSS 75

Query: 339 STDTGTLTIPAPTRGTDMGTLTIPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTD 398
              TGT+ +PA +  + +   +  +P       T  +P  T    L        H S   
Sbjct: 76  QDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGL-SEKSTTFHSSPRS 134

Query: 399 TGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYS- 457
             T   PA T          G +  S+T+  R    H       ++T    RH    +S 
Sbjct: 135 PATTLSPASTTS-------SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 187

Query: 458 --STDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGR--SLFQHRH 513
             STDT  L     T G    ST   T   +  +  T +   +  AL+ G+  + F    
Sbjct: 188 PGSTDTTLLPASTTTSGPSQEST---TSHSSPGSTDTALSPGSTTALSFGQESTTFHSSP 244

Query: 514 GDAH--YCSTDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTRGAHYSSTDTGTLTIAAPTR 571
           G  H          S +       H S+    T   PA +         T   T  A T 
Sbjct: 245 GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTH 304

Query: 572 GCSLFQHRHGAPTRGCSLFQHQHGD---THY--SSTDTGH-RHGDAHYSSTDTGTLTIAA 625
                     AP    + +    G    TH+  SST +GH       +SS D    T ++
Sbjct: 305 TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 364

Query: 626 RTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQH-RHGDAHYSSTDTGTLTIPAP 684
                         +H+    T T      T    L Q      +   ST+    T P+P
Sbjct: 365 AHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSP 424

Query: 685 TRGRSLFQHRHGAPIWGRSLFQHRHGD---AHYSSTDT----GHRHGDAHYSSTDVGTLT 737
               +       AP+   + +  R       H+S++ T           H S     T  
Sbjct: 425 PGTTA-------APVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGSTETTA 477

Query: 738 IPAPTRGRSLFQHQHGDVHYSSTDRGMLTIPAPTRGTDTG 777
           +P  T    L +       + S+ R   T  +P   T +G
Sbjct: 478 LPGSTTTAGLSEK---STTFYSSPRSPDTTLSPASTTSSG 514


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 103/472 (21%), Positives = 151/472 (31%), Gaps = 59/472 (12%)

Query: 643  SSTDTGTLTIAARTQGRPLFQHRHGDAHYSSTDTGTLTIPAPTRGRSLFQHRHGAPIWGR 702
            SST T   + ++ T G     H        S+   T T P P R  +   H   +  + R
Sbjct: 374  SSTPTTHFSASSTTLG-----HSEESTPVHSSPVATATTPPPARSATS-GHVEESTAYHR 427

Query: 703  SLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPAPTRGRSLFQHQHGDVHYSSTD- 761
            S    +      SST +GH    A +  +   T +    T         H  +  + T  
Sbjct: 428  SPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTH 487

Query: 762  -RGMLTIP-------APTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGTLTIPAP 813
             R   TI        A     D    T+       S+L      +   S  M T  +P  
Sbjct: 488  FRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGS 547

Query: 814  TQGRSLFQHQHGDAHYSST---DTGTLTIAAPTRG---RSLLQHQHGAPTWGRSQFQHRH 867
            T    L   +     YSS    DT  L  +  + G    S   H     T   + F    
Sbjct: 548  TTKPGL--SEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTH-TTAFPGST 604

Query: 868  GDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSL------FQHRHGNTHYS-----STDTG 916
                     T +H+ P PT T   P  T   SL      F  R G+T  +     +T +G
Sbjct: 605  TMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASG 664

Query: 917  TLTITAPTRGGSLFQH----------RHGEAH-YSSTDTGTPTNPAPTQGRPLFQHRHGD 965
             L  + P    +   H          R GE+  + S  +   T PAP      F      
Sbjct: 665  LLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTT 724

Query: 966  AHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGDA---HYSSTDTGHRHGD 1022
            +H S +     H  A  T++ +        ++    +    G     H+  +DT    G+
Sbjct: 725  SHGSPSSIPTTHISARSTTSGL--------VEESTTYHSSPGSTQTMHFPESDTTSGRGE 776

Query: 1023 AHYTSTDMGTLTIPAPIQGRSLFQHQCGDVHNSSTDAGTLTIP--AVTRGRS 1072
               TS    T TI +     S    +    H+S     T   P  + T GRS
Sbjct: 777  ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS 828



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 169/821 (20%), Positives = 262/821 (31%), Gaps = 112/821 (13%)

Query: 336  HYSSTDTGTLTIPAPTRGTDMGTLTIPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYS 395
            H S     T  +PA +  + +   + P+P       T  +P  T    L +       YS
Sbjct: 505  HSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEK--STTFYS 562

Query: 396  ST---DTGTLTIPAPTRG---RSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGH 449
            S    DT  L     + G    S   H    + +++   G +       E+  S +  G 
Sbjct: 563  SPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGP 622

Query: 450  RHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLF 509
                    ST   +L     T  +   ST+T  L    P   T   +L         +  
Sbjct: 623  TDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLL----PDNTTASGLLEASMPVHSSTRS 678

Query: 510  QHRHGDAHYCSTDMGRSLLQHQHGDAHYSSIDAGTLT--IPAPTRGAHYSSTDTGTLTIA 567
             H        +T  G S   H    ++ +     T T     P+  +H S +   T  I+
Sbjct: 679  PHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHIS 738

Query: 568  APTRGCSLFQHRHGAPTRGCSLFQHQHGDT---HYSSTDTGHRHGDAHYSSTDTGTLTIA 624
            A +    L +          + +    G T   H+  +DT    G+   +S  + T TI+
Sbjct: 739  ARSTTSGLVEES--------TTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTIS 790

Query: 625  ARTRGRPLFQHRHGDAHNSSTDTGTLTI--AARTQGRPLFQHRHGDAHYSSTD-TGTLTI 681
            +               H+S   T T     ++ T GR         A +SS D TGT+ +
Sbjct: 791  SAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS----EESIASHSSQDATGTIVL 846

Query: 682  PAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDT---GHRHGDAHYSSTDVGTLTI 738
            PA +    L      +PI   S+       A   ST T     R    H S     T   
Sbjct: 847  PARSTNSVLLGESTTSPISSGSM----ETTALPGSTTTPGLSERSTTFHSSPRSPATTLS 902

Query: 739  PAPTRG-----RSLFQHQHGDVHYSSTDRGMLTIPAPTRGT--------DTGTLTIPALT 785
            PA T        S   H      +++      T P  +R +         T T  +PA T
Sbjct: 903  PASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAST 962

Query: 786  WGRSLLQHRHGDAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAAPTRG 845
                + +         ST+   L     T G S    +     YSS  +   T++  +  
Sbjct: 963  TTXLVGEPTTSPISSGSTETTALPGSTTTAGLS----EKSTTFYSSPRSPDTTLSPASTT 1018

Query: 846  RSLLQHQ----HGAPTWGRSQFQHRHGDT---HYCSNDTGTHTIPAPTGTLTIPAPTRGR 898
             S +  +    H  P  G +      G T         T +H+ P  T T   P  T   
Sbjct: 1019 SSGVSEESTTSHSRP--GSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTAS 1076

Query: 899  SL------FQHRHGNTHY-----SSTDTGTLTITAPTRGGSLFQH----------RHGEA 937
            SL      F    G+T       ++T +G L  + P    +              R GE+
Sbjct: 1077 SLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGES 1136

Query: 938  -HYSSTDTGTPTNPAPTQGRPLFQH----RHGD------AHYSSTDT--GHRHGDAHYTS 984
              + S  +   T PAP      F       HG        H+S++ T  G         S
Sbjct: 1137 TTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHS 1196

Query: 985  TDMGTLTIPAP--------IQGRPLFQHRHGDA---HYSSTDTGHRHGDAHYTSTDMGTL 1033
            + +   T P+P        ++    +    G     H+  + T     +   TS    T 
Sbjct: 1197 SPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTH 1256

Query: 1034 TIPAPIQGRSLFQHQCGDVHNSSTDAGTLTIP--AVTRGRS 1072
            TI +P    S    +    H+S     T   P  + T GRS
Sbjct: 1257 TISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRS 1297



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 186/839 (22%), Positives = 282/839 (33%), Gaps = 124/839 (14%)

Query: 248  TVVGAAQGSVATHSWEAKD----GPRATGPAQPKIQARFLLLQSHHSDTRALPTDT---G 300
            T+ G +Q S A+HS          P  T P+    ++        ++ T  LP +T   G
Sbjct: 249  TMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSG 308

Query: 301  TLTIPAPTRGSDTGMLTVPATTRG-CSLFQHRHGDDHYSSTDTGTLTIPAPTRGTDMGTL 359
             L    P   S TG    P TT    S   H      + S  +   T PAP+ GT    +
Sbjct: 309  LLEASTPVHSS-TGS---PHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPS-GTTSAFV 363

Query: 360  TIPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHG 419
             + + T  + P +      +   +   H        S+   T T P P R  +       
Sbjct: 364  KL-STTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEES 422

Query: 420  DAHYSSTNTGRSLFQHRHGEAHY--SSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSS 477
             A++ S  + +++        H+  SST  GH    A +  + T T +    T  A   +
Sbjct: 423  TAYHRSPGSTQTM--------HFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHT 474

Query: 478  TDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHY 537
            +   +L     T   D    TI   +   S   H   DA   +     S      GD+  
Sbjct: 475  SYHSSLGSTETTHFRD--SSTISGRSE-ESKASHSSPDAMATTVLPAGSTPSVLVGDSTP 531

Query: 538  SSIDAG---TLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHRHGAPTRGCSLFQHQH 594
            S I +G   T  +P  T     S   T   +         L      +     S   H  
Sbjct: 532  SPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSR 591

Query: 595  -GDTHY-----SSTDTG-HRHGDAHYSS---TDT----GTLTIAARTRGRPLFQHRHGDA 640
             G TH      S+T  G  +   A +SS   TDT    G+ T ++       F  R G  
Sbjct: 592  PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGST 651

Query: 641  H-----NSSTDTGTLTIAARTQGRPLFQH----------RHGDA-HYSSTDTGTLTIPAP 684
                  +++T +G L  +          H          R G++  + S  +   T PAP
Sbjct: 652  ETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAP 711

Query: 685  TRGRSLFQH----RHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPA 740
                S F       HG+P    S     H  A   ST +G       Y S+   T T+  
Sbjct: 712  PTTTSAFVEPSTTSHGSP----SSIPTTHISAR--STTSGLVEESTTYHSSPGSTQTMHF 765

Query: 741  PTRGRSLFQHQHGDVHYSSTDRGMLTIPAPTRGT------------DTGTLTIP--ALTW 786
            P    +  + +     +SST   + + P+ T                T T   P  + T 
Sbjct: 766  PESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS 825

Query: 787  GR---SLLQHRHGDAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAAPT 843
            GR   S+  H   DA       GT+ +PA +   S+   +   +  SS    T  +   T
Sbjct: 826  GRSEESIASHSSQDA------TGTIVLPARST-NSVLLGESTTSPISSGSMETTALPGST 878

Query: 844  RGRSLLQHQ---HGAPTWGRSQFQHRHGDTHYCSND-TGTHTIPAPTGTLTIPAPTRGRS 899
                L +     H +P    +        +   S + T +H+ P  T T   P  T    
Sbjct: 879  TTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPG 938

Query: 900  LFQHRHGNTHYS---STDTGTL-----------TITAPTRGGSL-------FQHRHGEAH 938
            L   RH  T +S   STDT  L             T+P   GS             G + 
Sbjct: 939  L--SRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSE 996

Query: 939  YSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQ 997
             S+T   +P +P  T   P      G +  S+  T H    + +T+   G+ T+P   Q
Sbjct: 997  KSTTFYSSPRSPDTTLS-PASTTSSGVSEEST--TSHSRPGSTHTTAFPGSTTMPGVSQ 1052



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 185/888 (20%), Positives = 288/888 (32%), Gaps = 149/888 (16%)

Query: 256  SVATHSWEAKDGPRATGPAQPKIQARFLLLQSHHSDTRALPTDTGTLTIPAPTRGSDTGM 315
            S   HSW + +  R   PA P   + F+      + +   P+   T  I A  R + +G+
Sbjct: 695  STTFHSWPSSNDTR---PAPPTTTSAFV---EPSTTSHGSPSSIPTTHISA--RSTTSGL 746

Query: 316  LTVPAT---TRGCSLFQH--------RHGDDHYSSTDTGTLTIPAPTRGTDMGTLTIPAP 364
            +    T   + G +   H          G++  +S  + T TI +    T    +  P  
Sbjct: 747  VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAP-STTSALVEEPTS 805

Query: 365  TRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTD-TGTLTIPAPTRGRSLFQHXHGDAHY 423
               +   T T   P    +  +     A +SS D TGT+ +PA +    L     G++  
Sbjct: 806  YHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLL----GESTT 861

Query: 424  SSTNTGRSLFQHRHGEAHYSSTDKGHRHRDA--HYSSTDTGTLTIPAPTQGAHYSSTDTG 481
            S  ++G        G    S+T  G   R    H S     T   PA T  +  S   T 
Sbjct: 862  SPISSGSMETTALPG----STTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTT 917

Query: 482  TLTIAAPTRGTDMW-MLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHYSSI 540
            + +    T  T      T P L+R  +      G     +T +  S      G+   S I
Sbjct: 918  SHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD--TTLLPASTTTXLVGEPTTSPI 975

Query: 541  DAG---TLTIPAPTRGAHYSSTDTGTLTIA-APTRGCSLFQHRHGAPTRGCSLFQHQHGD 596
             +G   T  +P  T  A  S   T   +   +P    S         +   +    + G 
Sbjct: 976  SSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGS 1035

Query: 597  THY-----SSTDTG-HRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTL 650
            TH      S+T  G  +   A +SS  +   T++ R+             H+    T T 
Sbjct: 1036 THTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETT 1095

Query: 651  TIAARTQGRPLFQH----------------------RHGDAH-YSSTDTGTLTIPAPTRG 687
             +   T    L +                       R G++  + S  +   T+PAP   
Sbjct: 1096 LLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTT 1155

Query: 688  RSLFQH----RHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPAPTR 743
             S F       HG+P    S     H  A  SST  G         S+ V   T P+P R
Sbjct: 1156 TSAFVELSTTSHGSP----SSIPTTHFSA--SSTTFGRSEESTTVHSSPVAPATTPSPAR 1209

Query: 744  GRSLFQHQHGDVHYSS-------------TDRGMLTIPAPTRGTDTGTLTIPALTWGRSL 790
              +    +    ++SS             T  G       +  + T T++ P  T   S 
Sbjct: 1210 STTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST--TSA 1267

Query: 791  LQHRHGDAHYCSTDMGTLTIP--APTQGRSLFQHQHGDAHYSSTDTG------------- 835
            L       H     + T   P  + T GRS    +   A +SS DT              
Sbjct: 1268 LVEEPTSYHSSPGSIATTHFPESSTTSGRS----EESTASHSSPDTNGITPLPAHFTTSG 1323

Query: 836  -----------------TLTIAAPTRGRS----LLQHQHGAPTWGRSQFQHRHGD----- 869
                             TL   A T G S    +L     +P    S             
Sbjct: 1324 RIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEP 1383

Query: 870  THYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITAPTRGGSL 929
            T   S    THT   P  T T    ++  + F  + G+T  ++   G++T ++  +  + 
Sbjct: 1384 TSLYSQAESTHTTAFPASTTT-SGLSQESTTFHSKPGSTE-TTLSPGSITTSSFAQEFTT 1441

Query: 930  FQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGT 989
               + G A  S+    + T P  ++    F    G    S+  T   H +     +   T
Sbjct: 1442 PHSQPGSA-LSTVSPASTTVPGLSEESTTFYSSPG----STETTAFSHSNTMSIHSQQST 1496

Query: 990  LTIPAPIQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPA 1037
                 P    P F H    A  ++TD G      H +S   GT  +PA
Sbjct: 1497 -----PFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPA 1539



 Score = 31.2 bits (69), Expect = 5.6
 Identities = 55/238 (23%), Positives = 84/238 (35%), Gaps = 24/238 (10%)

Query: 248  TVVGAAQGSVATHSWEAKDGPRAT-GPAQPKI-QARFLLLQSHHSDTRALP----TDTGT 301
            T  G  + S   HS  +   PR T  PA     Q      QS  S    +P    T +  
Sbjct: 1102 TASGLLEASTPVHS--STGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAF 1159

Query: 302  LTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGTDMGTLTI 361
            + +   + GS + + T   +    +  +       +SS      T P+P R T  G +  
Sbjct: 1160 VELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSP-VAPATTPSPARSTTSGLVEE 1218

Query: 362  PAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDA 421
                  +   T T+  P    +  +       +SST   T TI +P    S         
Sbjct: 1219 STAYHSSPGSTQTMHFPESSTASGRSEESRTSHSST---THTISSPPSTTSALVEEPTSY 1275

Query: 422  HYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRD-AHYSSTDTGTLTIPAPTQGAHYSST 478
            H S  +   + F         SST  G      A +SS DT  +T P P   AH++++
Sbjct: 1276 HSSPGSIATTHFPE-------SSTTSGRSEESTASHSSPDTNGIT-PLP---AHFTTS 1322



 Score = 30.4 bits (67), Expect = 9.5
 Identities = 73/359 (20%), Positives = 123/359 (34%), Gaps = 44/359 (12%)

Query: 303  TIPAPTRGSDTGML---TVPATTRGCSLFQH--------RHGDDHYSSTDTGTLTIPAPT 351
            T P+P R + +G++   T   ++ G +   H           ++  +S  + T TI +P 
Sbjct: 1203 TTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPP 1262

Query: 352  RGTDMGTLTIPAPTR-DTDPGTL-TIPAPTWGRSLFQHXHGDAHYSSTDTGTLT-IPA-- 406
              T   +  +  PT   + PG++ T   P    +  +     A +SS DT  +T +PA  
Sbjct: 1263 STT---SALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHF 1319

Query: 407  PTRGR----SLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTG 462
             T GR    + F    G    +  +T  +          YSS+    R  D   S     
Sbjct: 1320 TTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSS----RSPDQTLSPASMT 1375

Query: 463  TLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYC--- 519
            + +I       +  +  T T    A T        T   L++  + F  + G        
Sbjct: 1376 SSSISGEPTSLYSQAESTHTTAFPAST--------TTSGLSQESTTFHSKPGSTETTLSP 1427

Query: 520  -----STDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTR-GAHYSSTDTGTLTIAAPTRGC 573
                 S+        H    +  S++   + T+P  +     + S+   T T A      
Sbjct: 1428 GSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNT 1487

Query: 574  SLFQHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPL 632
                 +   P      F H       ++TD G      H SS  TGT  + AR+    L
Sbjct: 1488 MSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDL 1546


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 95/434 (21%), Positives = 144/434 (33%), Gaps = 63/434 (14%)

Query: 268  PRATGPAQPKIQARFLLLQSHHSDTRALPTDTGTLTIPAPTRG--------SDTGMLTVP 319
            P  +  A P        + +  + T      TG+   P+ T G        S T  +TVP
Sbjct: 4203 PATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVP 4262

Query: 320  A-TTRGCSLFQHRHGDDHYSST-DTGTLTIPAPTRGTDMGTLT-IPA----PTRDTDPGT 372
              +T   S  Q   G  H S+T  T T+T    T  +  GT T +PA     T  T    
Sbjct: 4263 TGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSF 4322

Query: 373  LTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSL 432
              IP+ + G +           S T T T T+   T   +        AH S+  T  + 
Sbjct: 4323 TAIPSSSLGTTW-------TRLSQTTTPTATMSTATPSST-----PETAHTSTVLTTTAT 4370

Query: 433  FQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGT 492
                 G     S+  G  H     ++T TG    P+ + G   +     + T    T G+
Sbjct: 4371 TTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGS 4430

Query: 493  DMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTR 552
             +   ++P  T         H      +T                +++  G++  P+ + 
Sbjct: 4431 TVTPSSVPGTT---------HTPTVLTTTT---------------TTVATGSMATPSSST 4466

Query: 553  GAHYSSTDTGTLTIAAPTRGCSLF-QHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDA 611
                ++         A T G SL     H   T   S      G TH +   TG  H  A
Sbjct: 4467 QTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPA 4526

Query: 612  HYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAHY 671
              ++T T   +  A +   P  +         +T  G  T  +RT            A  
Sbjct: 4527 --ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTT---------ATATP 4575

Query: 672  SSTDTGTLTIPAPT 685
            S T T TL   +PT
Sbjct: 4576 SKTRTSTLLPSSPT 4589



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 95/434 (21%), Positives = 143/434 (32%), Gaps = 63/434 (14%)

Query: 268  PRATGPAQPKIQARFLLLQSHHSDTRALPTDTGTLTIPAPTRG--------SDTGMLTVP 319
            P  +  A P        + +  + T      TG+   P+ T G        S T  +TVP
Sbjct: 3056 PATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVP 3115

Query: 320  A-TTRGCSLFQHRHGDDHYSST-DTGTLTIPAPTRGTDMGTLT-IPA----PTRDTDPGT 372
              +T   S  Q   G  H S+T  T T+T    T  +  GT T +PA     T  T    
Sbjct: 3116 TGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSF 3175

Query: 373  LTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSL 432
              IP+ + G +           S T T T T+   T   +         H S+  T  + 
Sbjct: 3176 TAIPSSSLGTTW-------TRLSQTTTPTATMSTATPSST-----PETVHTSTVLTTTAT 3223

Query: 433  FQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGT 492
                 G     S+  G  H     ++T TG    P+ + G   +     + T    TRG+
Sbjct: 3224 TTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGS 3283

Query: 493  DMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTR 552
             +   +IP  T         H      +T                +++  G++  P+ + 
Sbjct: 3284 TVTPSSIPGTT---------HTPTVLTTTT---------------TTVATGSMATPSSST 3319

Query: 553  GAHYSSTDTGTLTIAAPTRGCSLF-QHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDA 611
                ++         A T G SL     H   T   S      G TH +   TG  H  A
Sbjct: 3320 QTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPA 3379

Query: 612  HYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAHY 671
              ++T T   +  A +   P  +         +T  G     +RT            A  
Sbjct: 3380 --ATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTT---------ATATP 3428

Query: 672  SSTDTGTLTIPAPT 685
            S T T TL   +PT
Sbjct: 3429 SKTRTSTLLPSSPT 3442



 Score = 37.4 bits (85), Expect = 0.078
 Identities = 57/227 (25%), Positives = 84/227 (37%), Gaps = 21/227 (9%)

Query: 289  HSDTRALPTDTGTLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTL-TI 347
            +S   + P  + T T P+ T G+ T +LT P TT   +           ++T T TL T 
Sbjct: 2575 YSHCPSTPATSSTAT-PSSTPGT-TWILTKPTTTATTT------ASTGSTATPTSTLRTA 2626

Query: 348  PAP---TRGTDMGTLTIPAPTRDTDPGTLT-IPA-------PTWGRSLFQHXHGDAHYSS 396
            P P   T      T+T    T  + PGT T +PA       PT   S+          + 
Sbjct: 2627 PPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPT-ATSVTPIPSSSLGTTW 2685

Query: 397  TDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHY 456
            T     T P  T   +        AH S+  T  +      G     S+  G  H     
Sbjct: 2686 TRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVP 2745

Query: 457  SSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALT 503
            ++T TG    P+ + G   +     + T    TRG+ +   +IP  T
Sbjct: 2746 TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTT 2792



 Score = 37.4 bits (85), Expect = 0.078
 Identities = 166/807 (20%), Positives = 248/807 (30%), Gaps = 80/807 (9%)

Query: 299  TGTLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGTDMGT 358
            TG    P+ T G+ T +LT P+TT   ++          +    GTL +   T  T   T
Sbjct: 3731 TGPTATPSSTPGT-TWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTP--T 3787

Query: 359  LTIPAPTRDTDPGTLT-IPA-------PTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRG 410
            +     T  + PGT T +PA       PT   S+          + T     T P  T  
Sbjct: 3788 VISSRATPSSSPGTATALPALRSTATTPT-ATSVTAIPSSSLGTAWTRLSQTTTPTATMS 3846

Query: 411  RSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPT 470
             +         H S+  T  +      G     S+  G  H     ++T TG    P+ +
Sbjct: 3847 TATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSS 3906

Query: 471  QGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQH 530
             G   +     + T    TRG+ +   +IP  T   ++           S     S  Q 
Sbjct: 3907 PGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQ- 3965

Query: 531  QHGDAHYSSIDAGTLTI---------PAPTRGAHYSS----------TDTGTLTIAAPTR 571
              G  H   +   T T          P   R A  S+          T+  T+T   P  
Sbjct: 3966 TSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAA 4025

Query: 572  GCSLFQHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRP 631
              S  QH   A +      +         +T  GH  G +  ++T T      ++TR   
Sbjct: 4026 TTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATAT-----PSKTRTST 4080

Query: 632  LFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAHYSSTDTGTLTIPAPTRGRSLF 691
            L          SS  +  +T    T   P          +S     +  +P P+ G   F
Sbjct: 4081 LLP--------SSPTSAPITTVVTTGCEP-------QCAWSEWLDYSYPMPGPSGGD--F 4123

Query: 692  QHRHGAPIWGRSLFQHRHGDAHYSSTDTG---HRHGDAHYSSTDVGTLTIPAPTRGRSLF 748
                     G ++ +   G    +    G      G     S D G +       G+   
Sbjct: 4124 DTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKM 4183

Query: 749  QHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGTL 808
               + ++     + G       T  T T + T P  TW  + L          +   G+ 
Sbjct: 4184 CFNY-EIRVFCCNYGHCPSTPATSSTATPSST-PGTTWILTKLT----TTATTTESTGST 4237

Query: 809  TIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRHG 868
              P+ T G +    +       +  TG+   A+ T+  +   H     T   +       
Sbjct: 4238 ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPH---VSTTATTPTVTSSK 4294

Query: 869  DTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGN--THYSSTDTGTLTITAPTRG 926
             T + S  T T  +PA   T T P  T   ++     G   T  S T T T T++  T  
Sbjct: 4295 ATPFSSPGTAT-ALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS 4353

Query: 927  GSLFQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTD 986
             +        AH S+  T T T    T          G AH +   T    G     S+ 
Sbjct: 4354 ST-----PETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSS 4408

Query: 987  MGTLTIPAPIQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQGRSLFQ 1046
             GT   P             G     S+  G  H     T+T   T      +   S   
Sbjct: 4409 PGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTT--TTVATGSMATPSSST 4466

Query: 1047 HQCGDVHNSSTDAGTLTIPAVTRGRSL 1073
               G  H       T    A T GRSL
Sbjct: 4467 QTSGTTHTPPVPNTT----ATTHGRSL 4489



 Score = 30.8 bits (68), Expect = 7.3
 Identities = 63/247 (25%), Positives = 84/247 (34%), Gaps = 47/247 (19%)

Query: 731  TDVGTLTIPAPTRGRSLFQHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSL 790
            T +   T P  T   +        VH S+    +LT  A T G  TG++  P+ T G + 
Sbjct: 3188 TRLSQTTTPTATMSTATPSSTPETVHTST----VLTTTATTTGA-TGSVATPSSTPGTA- 3241

Query: 791  LQHRHGDAHYCSTDMGTLTIPAPTQG--RSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSL 848
                H      +T  G    P+ + G  R+L         + ST T   T  +     S+
Sbjct: 3242 ----HTTKVLTTTTTGFTATPSSSPGTARTL-------PVWISTTTTPTTRGSTVTPSSI 3290

Query: 849  LQHQHGAPTWGRSQFQHRHGDTHYCSNDTGT----HTIPAPTGTLTIPAPTRGRSLFQHR 904
                H       +      G     S+ T T    HT P P  T T    T GRSL    
Sbjct: 3291 PGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTAT----THGRSLSPSS 3346

Query: 905  H---------------GNTHYSSTDTGTLTITAPTRGGSLFQHRH---GEAHYSSTDTGT 946
                            G TH +   TGT    A T G +  QH        H SS  T +
Sbjct: 3347 PHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTT--QHSTPALSSPHPSSRTTES 3404

Query: 947  PTNPAPT 953
            P +P  T
Sbjct: 3405 PPSPGTT 3411



 Score = 30.4 bits (67), Expect = 9.5
 Identities = 30/93 (32%), Positives = 34/93 (36%), Gaps = 24/93 (25%)

Query: 879  THTIPAPTGTLTIPAPTRGRSLFQHRH---------------GNTHYSSTDTGTLTITAP 923
            THT P P  T T    T GRSL                    G TH +   TGT    A 
Sbjct: 4472 THTPPVPNTTAT----THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAA 4527

Query: 924  TRGGSLFQHRH---GEAHYSSTDTGTPTNPAPT 953
            T G +  QH        H SS  T +P +P  T
Sbjct: 4528 TTGTT--QHSTPALSSPHPSSRTTESPPSPGTT 4558


>gi|169217460 PREDICTED: similar to Mucin-6, partial [Homo sapiens]
          Length = 350

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 65/221 (29%), Positives = 78/221 (35%), Gaps = 38/221 (17%)

Query: 296 PTDTGTLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTD-------TGTLTIP 348
           PT  G+ T  A T  + +  LT P TT   S      G    SST          T T P
Sbjct: 125 PTSIGSSTPMAHTTSATSSRLTTPFTTHSPST-----GSSPVSSTGPMTATSFQTTTTYP 179

Query: 349 APTRG-TDMGTLTIPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAP 407
            P+   T + T   P  T    P T T+  P   +         A   ST TG  TIP P
Sbjct: 180 TPSLSQTTLPTYVPPFSTSLVTPSTHTVITPPRTQMA-----TSASIHSTPTG--TIPPP 232

Query: 408 TRGRSLFQHXHGDAHYSSTNT----GRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGT 463
           T  ++      G  H + T T    G S        A  S++   H     H  +T T T
Sbjct: 233 TTLKAT-----GSTHTAPTRTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHPEATSTST 287

Query: 464 LTI-PAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALT 503
             I P P        T TGT T  A T       LT P  T
Sbjct: 288 TNITPNP--------TSTGTGTPVAHTTSATSSRLTTPFTT 320


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 188/873 (21%), Positives = 277/873 (31%), Gaps = 181/873 (20%)

Query: 220  GLAVRRVSGRVRVFAKHSRDARVRIRGVTVVGAAQGSVATHSWEAKDGPRATGPAQPKIQ 279
            G++V  ++G      KH  D+       T  G ++ S  +HS     GP ATG       
Sbjct: 52   GVSVTFITGSTAT--KHFLDSS------TNSGHSEESTVSHS-----GPGATGTT----- 93

Query: 280  ARFLLLQSHHSDTRALPTDTGTLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSS 339
                 L   HS T     +  T   P  +   +T  L    TT G S          YSS
Sbjct: 94   -----LFPSHSATSVFVGEPKTS--PITSASMETTALPGSTTTAGLS----EKSTTFYSS 142

Query: 340  TDTGTLTIPAPTRGTDMGTLTIPAPTRDTDPG---TLTIPAPTWGRSLFQHXHGDAHYSS 396
              +   T+ +P R T  G ++  + T  + PG   T+  P  T    + Q     +H   
Sbjct: 143  PRSPDRTL-SPARTTSSG-VSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTA-SHSIP 199

Query: 397  TDTGTLTIPAPTRGRSLFQHX---HGDAHYSST-----NTGRSLFQHRHGEAHYSSTDKG 448
              T T   P  T   SL       H    Y+ T     NT  S         H SST   
Sbjct: 200  GSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVH-SSTGSP 258

Query: 449  HRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSL 508
            H       S+T  G  T    T  +  SS DT      AP+  T  ++          S 
Sbjct: 259  HTTLSPSSSTTHEGEPT----TFQSWPSSKDTSP----APSGTTSAFVKLSTTYHSSPSS 310

Query: 509  FQHRHGDAHYCSTDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTRGAHYSSTDTGTLTIAA 568
                H  A   ST +G S    +    H S +   T T P P R A     +  T     
Sbjct: 311  TPTTHFSAS--STTLGHS---EESTPVHSSPV--ATATTPPPARSATSGHVEESTAY--- 360

Query: 569  PTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTR 628
                       H +P    ++   +   T   S ++   HG   ++ + T + T A    
Sbjct: 361  -----------HRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALA-- 407

Query: 629  GRPLFQHRHGDAHNS--STDTGTLTIAARTQGRPLFQHRHGDAHYSSTDT-GTLTIPAPT 685
                    H   H+S  ST+T     ++   GR         A +SS D   T  +PA +
Sbjct: 408  --------HTSYHSSLGSTETTHFRDSSTISGRS----EESKASHSSPDAMATTVLPAGS 455

Query: 686  RGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIPAPTRGR 745
                L      +PI                             SS  + T  +P  T   
Sbjct: 456  TPSVLVGDSTPSPI-----------------------------SSGSMETTALPGSTTKP 486

Query: 746  SLFQHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDM 805
             L +       + S+ R   T   P R T +G           S   H    + + +   
Sbjct: 487  GLSEKS---TTFYSSPRSPDTTHLPARMTSSGVSE-------ESTTSHSRPGSTHTTAFP 536

Query: 806  GTLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQH 865
            G+ T+P  +Q  +        +H S   T T      T   SL       P +       
Sbjct: 537  GSTTMPGLSQESTA-------SHSSPGPTDTTLSPGSTTASSL------GPEY------- 576

Query: 866  RHGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITAPTR 925
                       T  H+ P  T T  +P  T    L +    +T   S+     T  +P  
Sbjct: 577  -----------TTFHSSPGSTETTLLPDNTTASGLLE---ASTPVHSSTRSPHTTLSPAG 622

Query: 926  GGSLFQHRHGEAH-YSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTS 984
              +    R GE+  + S  +   T PAP      F      +H S +     H  A  T+
Sbjct: 623  STT----RQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTT 678

Query: 985  TDMGTLTIPAPIQGRPLFQHRHGDA---HYSSTDTGHRHGDAHYTSTDMGTLTIPAPIQG 1041
            + +        ++    +    G     H+  +DT    G+   TS    T TI +    
Sbjct: 679  SGL--------VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPST 730

Query: 1042 RSLFQHQCGDVHNSSTDAGTLTIP--AVTRGRS 1072
             S    +    H+S     T   P  + T GRS
Sbjct: 731  TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS 763



 Score = 31.6 bits (70), Expect = 4.3
 Identities = 79/383 (20%), Positives = 127/383 (33%), Gaps = 32/383 (8%)

Query: 336 HYSSTDTGTLTIPAPTRGTDMGTLTIPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYS 395
           H S     T  +PA +  + +   + P+P       T  +P  T    L +       YS
Sbjct: 440 HSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEK--STTFYS 497

Query: 396 ST---DTGTLTIPAPTRG---RSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGH 449
           S    DT  L     + G    S   H    + +++   G +       E+  S +  G 
Sbjct: 498 SPRSPDTTHLPARMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGP 557

Query: 450 RHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLF 509
                   ST   +L     T  +   ST+T  L    P   T   +L         +  
Sbjct: 558 TDTTLSPGSTTASSLGPEYTTFHSSPGSTETTLL----PDNTTASGLLEASTPVHSSTRS 613

Query: 510 QHRHGDAHYCSTDMGRSLLQHQHGDAHYSSIDAGTLT--IPAPTRGAHYSSTDTGTLTIA 567
            H        +T  G S   H    +  +     T T     P+  +H S +   T  I+
Sbjct: 614 PHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHIS 673

Query: 568 APTRGCSLFQHRHGAPTRGCSLFQHQHGDT---HYSSTDTGHRHGDAHYSSTDTGTLTIA 624
           A +    L +          + +    G T   H+  +DT    G+   +S  + T TI+
Sbjct: 674 ARSTTSGLVEES--------TTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTIS 725

Query: 625 ARTRGRPLFQHRHGDAHNSSTDTGTLTI--AARTQGRPLFQHRHGDAHYSSTD-TGTLTI 681
           +               H+S   T T     ++ T GR         A +SS D TGT+ +
Sbjct: 726 SAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS----EESTASHSSQDATGTIVL 781

Query: 682 PAPTRGRSLFQHRHGAPIWGRSL 704
           PA +    L      +PI   S+
Sbjct: 782 PARSTNSVLLGESTTSPISSGSM 804


>gi|39995080 hypothetical protein LOC79567 [Homo sapiens]
          Length = 1219

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 43/149 (28%), Positives = 58/149 (38%), Gaps = 14/149 (9%)

Query: 287 SHHSDTRALPTDTGTLTIPAPTRGSDTGMLTVPATTRGCS--LFQHRHGDDHY----SST 340
           S H D+    TD+G   +P PT  +     +   TT      L     G  H     + T
Sbjct: 524 SAHLDSVHKSTDSGPSELPGPTHTTTGSTYSAITTTHSAPSPLTHTTTGSTHKPIISTLT 583

Query: 341 DTG-TLTIPAPTRGTDMGTLTIPAPTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDT 399
            TG TL I  P + T   T T+P+PT  T   T T  +PT             H +S   
Sbjct: 584 TTGPTLNIIGPVQTTTSPTHTMPSPTHTTASPTHTSTSPT------HTPTSPTHKTSMSP 637

Query: 400 GTLTIPAPTRGRSLFQHXHGDAHYSSTNT 428
            T T P P+ G  L Q      H +++ T
Sbjct: 638 PTTTSPTPS-GMGLVQTATSPTHPTTSPT 665



 Score = 37.4 bits (85), Expect = 0.078
 Identities = 58/200 (29%), Positives = 76/200 (38%), Gaps = 39/200 (19%)

Query: 700 WGRSLFQH---RHGDAHYS----STDTGHRHGDAHYSST-DVGTLTIPAPTRGRSLFQHQ 751
           WG S   H    HG+ H S    + D GH    +   +T  V T T PAP+         
Sbjct: 475 WGPSPPTHPAPTHGE-HPSPVPPALDPGHSATSSTLGTTGSVPTSTDPAPSA-------- 525

Query: 752 HGDVHYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRS----LLQHRHGDAHYCSTDMGT 807
           H D  + STD G   +P PT  T TG+ T  A+T   S    L     G  H     + T
Sbjct: 526 HLDSVHKSTDSGPSELPGPTH-TTTGS-TYSAITTTHSAPSPLTHTTTGSTH--KPIIST 581

Query: 808 LTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQHGAPTWGRSQFQHRH 867
           LT   PT                +T + T T+ +PT   +   H   +PT   +      
Sbjct: 582 LTTTGPTLNII--------GPVQTTTSPTHTMPSPTHTTASPTHTSTSPTHTPT------ 627

Query: 868 GDTHYCSNDTGTHTIPAPTG 887
             TH  S    T T P P+G
Sbjct: 628 SPTHKTSMSPPTTTSPTPSG 647



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 45/181 (24%), Positives = 68/181 (37%), Gaps = 25/181 (13%)

Query: 867  HGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGNTHYSSTDT-----GTLTIT 921
            H D+ + S D+G   +P PT T T    +   +        TH ++  T      TLT T
Sbjct: 526  HLDSVHKSTDSGPSELPGPTHTTTGSTYSAITTTHSAPSPLTHTTTGSTHKPIISTLTTT 585

Query: 922  APTRGGSLFQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAH 981
             PT       +  G    +++ T T  +P  T   P         H S++ T       H
Sbjct: 586  GPT------LNIIGPVQTTTSPTHTMPSPTHTTASP--------THTSTSPTHTPTSPTH 631

Query: 982  YTSTDMGTLTIPAPIQGRPLFQHRHGDAHYSSTDTGHRHGD-----AHYTSTDMGTLTIP 1036
             TS    T T P P  G  L Q      H +++ T           +  TS ++ TL+ P
Sbjct: 632  KTSMSPPTTTSPTP-SGMGLVQTATSPTHPTTSPTHPTTSPILINVSPSTSLELATLSSP 690

Query: 1037 A 1037
            +
Sbjct: 691  S 691



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 70/304 (23%), Positives = 110/304 (36%), Gaps = 36/304 (11%)

Query: 403 TIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHY--SSTDKG-HRHRDAHYSST 459
           T PAPT G       H      + + G S      G      +STD     H D+ + ST
Sbjct: 481 THPAPTHGE------HPSPVPPALDPGHSATSSTLGTTGSVPTSTDPAPSAHLDSVHKST 534

Query: 460 DTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAHYC 519
           D+G   +P PT     S+    T T +AP+            LT   +   H+   +   
Sbjct: 535 DSGPSELPGPTHTTTGSTYSAITTTHSAPS-----------PLTHTTTGSTHKPIISTLT 583

Query: 520 STDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQHR 579
           +T    +++    G    ++    T+  P  T  +   ++ + T T  +PT   S+    
Sbjct: 584 TTGPTLNII----GPVQTTTSPTHTMPSPTHTTASPTHTSTSPTHTPTSPTHKTSMSPPT 639

Query: 580 HGAPT-RGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHG 638
             +PT  G  L Q     TH +++ T         + + + +L +A  T   P    +H 
Sbjct: 640 TTSPTPSGMGLVQTATSPTHPTTSPTHPTTSPILINVSPSTSLELA--TLSSP---SKHS 694

Query: 639 DAHNSSTDT---GTLTIAARTQGRPLFQHR-HGDAHYSSTDTGTLTIPAPTRGRSLFQHR 694
           D     TD+         + TQ  P+     H    +SS     LT PAP    S  Q  
Sbjct: 695 DPTLPGTDSLPCSPPVSNSYTQADPMAPRTPHPSPAHSSRK--PLTSPAPDPSESTVQSL 752

Query: 695 HGAP 698
              P
Sbjct: 753 SPTP 756



 Score = 32.0 bits (71), Expect = 3.3
 Identities = 37/146 (25%), Positives = 50/146 (34%), Gaps = 24/146 (16%)

Query: 947  PTNPAPTQGR------PLFQHRH----------GDAHYSSTDTGHRHGDAHYTSTDMGTL 990
            PT+PAPT G       P     H          G    S+      H D+ + STD G  
Sbjct: 480  PTHPAPTHGEHPSPVPPALDPGHSATSSTLGTTGSVPTSTDPAPSAHLDSVHKSTDSGPS 539

Query: 991  TIPAPIQG------RPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMG-TLTIPAPIQGRS 1043
             +P P           +       +  + T TG  H     T T  G TL I  P+Q  +
Sbjct: 540  ELPGPTHTTTGSTYSAITTTHSAPSPLTHTTTGSTHKPIISTLTTTGPTLNIIGPVQTTT 599

Query: 1044 LFQHQC-GDVHNSSTDAGTLTIPAVT 1068
               H      H +++   T T P  T
Sbjct: 600  SPTHTMPSPTHTTASPTHTSTSPTHT 625



 Score = 31.2 bits (69), Expect = 5.6
 Identities = 48/189 (25%), Positives = 71/189 (37%), Gaps = 25/189 (13%)

Query: 303 TIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGTDMGTLTIP 362
           T PAPT G     +  PA   G S      G    ++    T T PAP+   D       
Sbjct: 481 THPAPTHGEHPSPVP-PALDPGHSATSSTLG----TTGSVPTSTDPAPSAHLD------- 528

Query: 363 APTRDTDPGTLTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAH 422
           +  + TD G   +P PT       H    + YS+  T T + P+P    +     H    
Sbjct: 529 SVHKSTDSGPSELPGPT-------HTTTGSTYSAITT-THSAPSPLT-HTTTGSTHKPII 579

Query: 423 YSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIP--APTQGAHYSSTDT 480
            + T TG +L  +  G    +++         H +++ T T T P   PT   H +S   
Sbjct: 580 STLTTTGPTL--NIIGPVQTTTSPTHTMPSPTHTTASPTHTSTSPTHTPTSPTHKTSMSP 637

Query: 481 GTLTIAAPT 489
            T T   P+
Sbjct: 638 PTTTSPTPS 646


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 39.7 bits (91), Expect = 0.016
 Identities = 60/251 (23%), Positives = 89/251 (35%), Gaps = 27/251 (10%)

Query: 268  PRATGPAQPKIQARFLLLQSHHSDTRALPTDTGTLTIPAPTRG--------SDTGMLTVP 319
            P  +  A P        + +  + T      TG+   P+ T G        S T  +TVP
Sbjct: 2421 PATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVP 2480

Query: 320  A-TTRGCSLFQHRHGDDHYSST-DTGTLTIPAPTRGTDMGTLT-IPA----PTRDTDPGT 372
              +T   S  Q   G  H S+T  T T+T    T  +  GT T +PA     T  T    
Sbjct: 2481 TGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSF 2540

Query: 373  LTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSL 432
              IP+ + G +           S T T T T+   T   +         H S+  T  + 
Sbjct: 2541 TAIPSSSLGTTW-------TRLSQTTTPTATMSTATPSST-----PETVHTSTVLTTTAT 2588

Query: 433  FQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGT 492
                 G     S+  G  H     ++T TG    P+ + G   +     + T    TRG+
Sbjct: 2589 TTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGS 2648

Query: 493  DMWMLTIPALT 503
             +   +IP  T
Sbjct: 2649 TVTPSSIPGTT 2659



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 106/465 (22%), Positives = 149/465 (32%), Gaps = 70/465 (15%)

Query: 268  PRATGPAQPKIQARFLLLQSHHSDTRALPTDTGTLTIPAPTRG--------SDTGMLTVP 319
            P  +  A P        + +  + T      TG+   P+ T G        S T  +TVP
Sbjct: 3678 PATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVP 3737

Query: 320  A-TTRGCSLFQHRHGDDHYSST-DTGTLTIPAPTRGTDMGTLT-IPA----PTRDTDPGT 372
              +T   S  Q   G  H S+T  T T+T    T  +  GT T +PA     T  T    
Sbjct: 3738 TGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSF 3797

Query: 373  LTIPAPTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSL 432
              IP+ + G +           S T T T T+   T   +        AH S+  T  + 
Sbjct: 3798 TAIPSSSLGTTW-------TRLSQTTTPTATMSTATPSST-----PETAHTSTVLTTTAT 3845

Query: 433  FQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGT 492
                 G     S+  G  H     ++T TG    P+ + G   +     + T    T G+
Sbjct: 3846 TTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGS 3905

Query: 493  DMWMLTIPALTRGRSLFQHRHGDAHYCSTDMGRSLLQHQ---------------HGDAHY 537
             +   ++P  T   ++           S     S  Q                  G    
Sbjct: 3906 TVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTN 3965

Query: 538  SSIDAGTLTIP-----APTRGAHYSSTDTGTLTI-----------AAPTRGCSLF-QHRH 580
             S   GT  IP       T  A  SST T +  +            A T G SL     H
Sbjct: 3966 PSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPH 4025

Query: 581  GAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDA 640
               T   S      G TH +   TG  H  A  ++T T   +  A +   P  +      
Sbjct: 4026 TVRTAWTSATSGTLGTTHITEPSTGTSHTPA--ATTGTTQHSTPALSSPHPSSRTTESPP 4083

Query: 641  HNSSTDTGTLTIAARTQGRPLFQHRHGDAHYSSTDTGTLTIPAPT 685
               +T  G  T  +RT            A  S T T TL   +PT
Sbjct: 4084 SPGTTTPGHTTATSRTT---------ATATPSKTRTSTLLPSSPT 4119



 Score = 38.5 bits (88), Expect = 0.035
 Identities = 117/513 (22%), Positives = 159/513 (30%), Gaps = 103/513 (20%)

Query: 457  SSTDTGTLTIPAPTQGAHYSSTD----------TGTLTIAAPTRGTDMWMLTIPALTRGR 506
            S+  T +  +P+ T G  +  T+          TG+    + T GT  W+LT P+ T   
Sbjct: 2419 STPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTT-WILTEPSTTATV 2477

Query: 507  SLFQHRHGDAHYCSTDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTRGAHYSSTDTGTLTI 566
            ++       A         S  Q   G  H S+    T T P  T       +  GT T 
Sbjct: 2478 TVPTGSTATA---------SSTQATAGTPHVST----TATTPTVTSSKATPFSSPGTATA 2524

Query: 567  AAPTRGCSLFQHRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAAR 626
                R          A T   + F      T   S+  G        ++T T T++ A  
Sbjct: 2525 LPALRST--------ATTPTATSF------TAIPSSSLGTTWTRLSQTTTPTATMSTATP 2570

Query: 627  TRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAH----YSSTDTGTLTIP 682
            +   P   H       ++T TG     A     P      G AH     ++T TG    P
Sbjct: 2571 S-STPETVHTSTVLTTTATTTGATGSVATPSSTP------GTAHTTKVLTTTTTGFTATP 2623

Query: 683  APTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGT------L 736
            + + G +        P+W              S+T T    G     S+  GT      L
Sbjct: 2624 SSSPGTA-----RTLPVW-------------ISTTTTPTTRGSTVTPSSIPGTTHTPTVL 2665

Query: 737  TIPAPTRGRSLFQHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHG 796
            T    T               S T   + T    T  T TG+ T P+ T G + +     
Sbjct: 2666 TTTTTTVATGSMATPSSSTQTSGTPPSLTT--TATTITATGSTTNPSSTPGTTPIP---- 2719

Query: 797  DAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQ-HGA 855
                      T T PA T          G  H       T T    T GRSL     H  
Sbjct: 2720 -----PVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTAT----THGRSLSPSSPHTV 2770

Query: 856  PTWGRSQFQHRHGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGNTHYSSTDT 915
             T   S      G TH     TGT   PA T   T             +H     SS   
Sbjct: 2771 RTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTT-------------QHSTPALSSPHP 2817

Query: 916  GTLTITAPTRGGSLFQHRHGEAHYSSTDTGTPT 948
             + T  +P   G+     H  A   +T T TP+
Sbjct: 2818 SSRTTESPPSPGTT-TPGHTRATSRTTATATPS 2849



 Score = 37.4 bits (85), Expect = 0.078
 Identities = 57/227 (25%), Positives = 84/227 (37%), Gaps = 21/227 (9%)

Query: 289  HSDTRALPTDTGTLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTL-TI 347
            +S   + P  + T T P+ T G+ T +LT P TT   +           ++T T TL T 
Sbjct: 1885 YSHCPSTPATSSTAT-PSSTPGT-TWILTKPTTTATTT------ASTGSTATPTSTLRTA 1936

Query: 348  PAP---TRGTDMGTLTIPAPTRDTDPGTLT-IPA-------PTWGRSLFQHXHGDAHYSS 396
            P P   T      T+T    T  + PGT T +PA       PT   S+          + 
Sbjct: 1937 PPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPT-ATSVTPIPSSSLGTTW 1995

Query: 397  TDTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHY 456
            T     T P  T   +        AH S+  T  +      G     S+  G  H     
Sbjct: 1996 TRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVP 2055

Query: 457  SSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALT 503
            ++T TG    P+ + G   +     + T    TRG+ +   +IP  T
Sbjct: 2056 TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTT 2102



 Score = 37.0 bits (84), Expect = 0.10
 Identities = 115/502 (22%), Positives = 154/502 (30%), Gaps = 93/502 (18%)

Query: 458  STDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDAH 517
            S+  GT  I         ++  TG+    + T GT  W+LT P+ T   ++       A 
Sbjct: 3687 SSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTT-WILTEPSTTATVTVPTGSTATA- 3744

Query: 518  YCSTDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLFQ 577
                    S  Q   G  H S+    T T P  T       +  GT T     R      
Sbjct: 3745 --------SSTQATAGTPHVST----TATTPTVTSSKATPFSSPGTATALPALRST---- 3788

Query: 578  HRHGAPTRGCSLFQHQHGDTHYSSTDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRH 637
                A T   + F      T   S+  G        ++T T T++ A  +          
Sbjct: 3789 ----ATTPTATSF------TAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPET----- 3833

Query: 638  GDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAHYS----STDTGTLTIPAPTRGRSLFQH 693
              AH S+  T T T    T          G AH +    +T TG    P+ + G +    
Sbjct: 3834 --AHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTA---- 3887

Query: 694  RHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGT------LTIPAPTRGRSL 747
                P+W              S+T T    G     S+  GT      LT    T     
Sbjct: 3888 -RTPPVW-------------ISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGS 3933

Query: 748  FQHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMGT 807
                      S T   ++T    T  T TG+ T P+ T G + +               T
Sbjct: 3934 MATPSSSTQTSGTPPSLIT--TATTITATGSTTNPSSTPGTTPIP---------PVLTTT 3982

Query: 808  LTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQ-HGAPTWGRSQFQHR 866
             T PA T          G  H       T T    T GRSL     H   T   S     
Sbjct: 3983 ATTPAATSSTVTPSSALGTTHTPPVPNTTAT----THGRSLSPSSPHTVRTAWTSATSGT 4038

Query: 867  HGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITAPTRG 926
             G TH     TGT   PA T   T             +H     SS    + T  +P   
Sbjct: 4039 LGTTHITEPSTGTSHTPAATTGTT-------------QHSTPALSSPHPSSRTTESPPSP 4085

Query: 927  GSLFQHRHGEAHYSSTDTGTPT 948
            G+     H  A   +T T TP+
Sbjct: 4086 GTT-TPGHTTATSRTTATATPS 4106



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 50/213 (23%), Positives = 76/213 (35%), Gaps = 12/213 (5%)

Query: 299  TGTLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGTDMGT 358
            TG    P+ T G+ T +LT P+TT   ++          +    GTL +   T  T   T
Sbjct: 3151 TGPTATPSSTPGT-TWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTP--T 3207

Query: 359  LTIPAPTRDTDPGTLT-IPA-------PTWGRSLFQHXHGDAHYSSTDTGTLTIPAPTRG 410
            +     T  + PGT T +PA       PT   S+          + T     T P  T  
Sbjct: 3208 VISSRATPSSSPGTATALPALRSTATTPT-ATSVTAIPSSSLGTAWTRLSQTTTPTATMS 3266

Query: 411  RSLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPT 470
             +         H S+  T  +      G     S+  G  H     ++T TG    P+ +
Sbjct: 3267 TATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSS 3326

Query: 471  QGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALT 503
             G   +     + T    TRG+ +   +IP  T
Sbjct: 3327 PGTALTPPVWISTTTTPTTRGSTVTPSSIPGTT 3359



 Score = 33.9 bits (76), Expect = 0.86
 Identities = 90/365 (24%), Positives = 115/365 (31%), Gaps = 70/365 (19%)

Query: 614  SSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRPLFQHRHGDAHY-- 671
            S T T T T++  T            AH S+  T T T    T          G AH   
Sbjct: 1999 SQTTTPTATMSTATPSST-----PETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTK 2053

Query: 672  --SSTDTGTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYS 729
              ++T TG    P+ + G +L       P+W              S+T T    G     
Sbjct: 2054 VPTTTTTGFTATPSSSPGTAL-----TPPVW-------------ISTTTTPTTRGSTVTP 2095

Query: 730  STDVGT------LTIPAPTRGRSLFQHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLTIPA 783
            S+  GT      LT    T               S T   + T    T  T TG+ T P+
Sbjct: 2096 SSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTT--TATTITATGSTTNPS 2153

Query: 784  LTWGRSLLQHRHGDAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAAPT 843
             T G + +               T T PA T          G  H            A T
Sbjct: 2154 STPGTTPIP---------PVLTTTATTPAATSNTVTPSSALGTTHTPPVP----NTMATT 2200

Query: 844  RGRSL-LQHQHGAPTWGRSQFQHRHGDTHYCSNDTGT-HTIPAPTGT-------LTIPAP 894
             GRSL     H   T   S      G TH     T T HT+ A TGT       L+ P P
Sbjct: 2201 HGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHP 2260

Query: 895  TRGRSLFQHRHGNT---HYSSTDTGTLTIT-APTRGGSLFQHRHGEAHYSSTDTGTPTNP 950
            +   +      G T   H ++T   T T T + TR  +L           S+ T  P   
Sbjct: 2261 SSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLL---------PSSPTSAPITT 2311

Query: 951  APTQG 955
              T G
Sbjct: 2312 VVTMG 2316



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 30/109 (27%), Positives = 43/109 (39%), Gaps = 10/109 (9%)

Query: 879  THTIPAPTGTLTIPAPTRGRSL--FQHRHGNTHYSSTDTGTLTITAPTRGGSLFQHRHGE 936
            THT P P  T T    T GRSL         T ++S  +G L  T  T   ++  H    
Sbjct: 3445 THTPPVPNTTAT----THGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPA- 3499

Query: 937  AHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTST 985
               ++T T   + PA +   P  +         +T  GH  G +  T+T
Sbjct: 3500 ---ATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTAT 3545



 Score = 30.4 bits (67), Expect = 9.5
 Identities = 49/202 (24%), Positives = 64/202 (31%), Gaps = 8/202 (3%)

Query: 874  SNDTGTHT-IPAPTGTLTIPAPTRGRSLFQHRHGNTHYSSTDTGTLTITAPTRGGSLFQH 932
            S+  GT T +PA   T T P  T    +     G T    + T T T T  T   S    
Sbjct: 1959 SSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE 2018

Query: 933  RHGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDMGTLTI 992
                AH S+  T T T    T          G AH +   T    G     S+  GT   
Sbjct: 2019 T---AHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALT 2075

Query: 993  PAPIQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTD----MGTLTIPAPIQGRSLFQHQ 1048
            P             G     S+  G  H     T+T      G++  P+     S     
Sbjct: 2076 PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPS 2135

Query: 1049 CGDVHNSSTDAGTLTIPAVTRG 1070
                  + T  G+ T P+ T G
Sbjct: 2136 LTTTATTITATGSTTNPSSTPG 2157



 Score = 30.4 bits (67), Expect = 9.5
 Identities = 30/93 (32%), Positives = 34/93 (36%), Gaps = 24/93 (25%)

Query: 879  THTIPAPTGTLTIPAPTRGRSLFQHRH---------------GNTHYSSTDTGTLTITAP 923
            THT P P  T T    T GRSL                    G TH +   TGT    A 
Sbjct: 2745 THTPPVPNTTAT----THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAA 2800

Query: 924  TRGGSLFQHRH---GEAHYSSTDTGTPTNPAPT 953
            T G +  QH        H SS  T +P +P  T
Sbjct: 2801 TTGTT--QHSTPALSSPHPSSRTTESPPSPGTT 2831



 Score = 30.4 bits (67), Expect = 9.5
 Identities = 30/93 (32%), Positives = 34/93 (36%), Gaps = 24/93 (25%)

Query: 879  THTIPAPTGTLTIPAPTRGRSLFQHRH---------------GNTHYSSTDTGTLTITAP 923
            THT P P  T T    T GRSL                    G TH +   TGT    A 
Sbjct: 4002 THTPPVPNTTAT----THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAA 4057

Query: 924  TRGGSLFQHRH---GEAHYSSTDTGTPTNPAPT 953
            T G +  QH        H SS  T +P +P  T
Sbjct: 4058 TTGTT--QHSTPALSSPHPSSRTTESPPSPGTT 4088


>gi|221316609 sperm-associated cation channel 1 [Homo sapiens]
          Length = 780

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 76/359 (21%), Positives = 118/359 (32%), Gaps = 52/359 (14%)

Query: 693  HRHGAPIW-GRSL----FQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTLTIP-APTRGRS 746
            H HG P   G S     FQ  H  A  S     H H +A       G      AP++G  
Sbjct: 46   HHHGVPHQRGESHHPPEFQDFHDQALSSHVHQSHHHSEARNHGRAHGPTGFGLAPSQGAV 105

Query: 747  LFQHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHGDAHYCSTDMG 806
                 +G+ ++    R              G        +G     H+  D+HY     G
Sbjct: 106  PSHRSYGEDYHDELQRD-------------GRRHHDGSQYGGF---HQQSDSHY---HRG 146

Query: 807  TLTIPAPTQGRSLFQHQHGDAHYSSTDTGTLTIAAPTRGRSLLQHQHG--APTWGRSQFQ 864
            +        G +L  +  G  H+           A   G S L H     + ++  S+  
Sbjct: 147  SHHGRPQYLGENLSHYSSGVPHHGE---------ASHHGGSYLPHGPNPYSESFHHSEAS 197

Query: 865  HRHGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQ--HRHGNT-HYSSTDTGTLTIT 921
            H  G  H   +++  H +P             GRS     H+HG + H+  T +   ++ 
Sbjct: 198  HLSGLQH---DESQHHQVPHRGWPHHHQVHHHGRSRHHEAHQHGKSPHHGETISPHSSVG 254

Query: 922  APTRGGSLFQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAH 981
            +  RG S +   + +  +  ++     +P  TQ      HRH D H      G  H    
Sbjct: 255  SYQRGISDYHSEYHQGDHHPSEYHHGDHPHHTQHHYHQTHRHRDYHQHQDHHGAYHSSYL 314

Query: 982  YTSTDMGTLTIPAPIQGRPLFQHRHGDAHYSSTDTG-------HRHGDAHYTSTDMGTL 1033
            +      T  +  P   R L     G A   ++ TG       H  G AH  +    T+
Sbjct: 315  HGDYVQSTSQLSIPHTSRSLIHDAPGPA---ASRTGVFPYHVAHPRGSAHSMTRSSSTI 370



 Score = 30.8 bits (68), Expect = 7.3
 Identities = 28/97 (28%), Positives = 32/97 (32%), Gaps = 6/97 (6%)

Query: 932  HRHGEA----HYSSTDTGTPTNPAPTQGRPLFQHRHGDAHYSSTDTGHRHGDAHYTSTDM 987
            HR G +    HY     G P     +   P FQ  H  A  S     H H +A       
Sbjct: 32   HRPGHSRALHHYELHHHGVPHQRGESHHPPEFQDFHDQALSSHVHQSHHHSEARNHGRAH 91

Query: 988  GTLTIP-APIQGRPLFQHRHG-DAHYSSTDTGHRHGD 1022
            G      AP QG       +G D H      G RH D
Sbjct: 92   GPTGFGLAPSQGAVPSHRSYGEDYHDELQRDGRRHHD 128


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 67/305 (21%), Positives = 112/305 (36%), Gaps = 26/305 (8%)

Query: 290  SDTRALPTDTGTLTIPAPTRGSDT-------GMLTVPATTRGC-SLFQHRHGDDHYSSTD 341
            S+T  + T  G+ TIPA T GS+T       G  T  A+T G  +        +  ++T 
Sbjct: 820  SETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 342  TGTLTIPAPTRGTDMGTLTI---PAPTRDTDPGTLTIPAPTWGRSLFQHXHG-DAHYSST 397
             G+ T  A T G++  T +       T  T+   +T  + T   +      G +   +ST
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 398  DTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTG-RSLFQHRHGEAHYSSTDKGHRHRDAHY 456
            +   LT  + T   ++     G    + T  G  +      G    + +  G     A  
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASI 998

Query: 457  SSTD------TGTLTIPAPTQGAHYSSTDT-GTLTIAAPTRGTDMWMLTIPALTRGRSLF 509
              ++      TG+ T    T G   + T T G+ T    T G++    T    T   +  
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE---TTAVYTTGSETTT 1055

Query: 510  QHRHGDAHYCSTDMGRSLLQHQHGDAHYSSID-AGTLTIPAPTRGAHYSST-DTGTLTIA 567
                G      +  G         D   +++  +G+ T  A T G+  ++   TG+ T  
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT 1115

Query: 568  APTRG 572
            A T G
Sbjct: 1116 ASTEG 1120


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 67/305 (21%), Positives = 112/305 (36%), Gaps = 26/305 (8%)

Query: 290  SDTRALPTDTGTLTIPAPTRGSDT-------GMLTVPATTRGC-SLFQHRHGDDHYSSTD 341
            S+T  + T  G+ TIPA T GS+T       G  T  A+T G  +        +  ++T 
Sbjct: 820  SETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 342  TGTLTIPAPTRGTDMGTLTI---PAPTRDTDPGTLTIPAPTWGRSLFQHXHG-DAHYSST 397
             G+ T  A T G++  T +       T  T+   +T  + T   +      G +   +ST
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 398  DTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTG-RSLFQHRHGEAHYSSTDKGHRHRDAHY 456
            +   LT  + T   ++     G    + T  G  +      G    + +  G     A  
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASI 998

Query: 457  SSTD------TGTLTIPAPTQGAHYSSTDT-GTLTIAAPTRGTDMWMLTIPALTRGRSLF 509
              ++      TG+ T    T G   + T T G+ T    T G++    T    T   +  
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE---TTAVYTTGSETTT 1055

Query: 510  QHRHGDAHYCSTDMGRSLLQHQHGDAHYSSID-AGTLTIPAPTRGAHYSST-DTGTLTIA 567
                G      +  G         D   +++  +G+ T  A T G+  ++   TG+ T  
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT 1115

Query: 568  APTRG 572
            A T G
Sbjct: 1116 ASTEG 1120


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 67/305 (21%), Positives = 112/305 (36%), Gaps = 26/305 (8%)

Query: 290  SDTRALPTDTGTLTIPAPTRGSDT-------GMLTVPATTRGC-SLFQHRHGDDHYSSTD 341
            S+T  + T  G+ TIPA T GS+T       G  T  A+T G  +        +  ++T 
Sbjct: 820  SETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 342  TGTLTIPAPTRGTDMGTLTI---PAPTRDTDPGTLTIPAPTWGRSLFQHXHG-DAHYSST 397
             G+ T  A T G++  T +       T  T+   +T  + T   +      G +   +ST
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 398  DTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTG-RSLFQHRHGEAHYSSTDKGHRHRDAHY 456
            +   LT  + T   ++     G    + T  G  +      G    + +  G     A  
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASI 998

Query: 457  SSTD------TGTLTIPAPTQGAHYSSTDT-GTLTIAAPTRGTDMWMLTIPALTRGRSLF 509
              ++      TG+ T    T G   + T T G+ T    T G++    T    T   +  
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE---TTAVYTTGSETTT 1055

Query: 510  QHRHGDAHYCSTDMGRSLLQHQHGDAHYSSID-AGTLTIPAPTRGAHYSST-DTGTLTIA 567
                G      +  G         D   +++  +G+ T  A T G+  ++   TG+ T  
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT 1115

Query: 568  APTRG 572
            A T G
Sbjct: 1116 ASTEG 1120


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 67/305 (21%), Positives = 112/305 (36%), Gaps = 26/305 (8%)

Query: 290  SDTRALPTDTGTLTIPAPTRGSDT-------GMLTVPATTRGC-SLFQHRHGDDHYSSTD 341
            S+T  + T  G+ TIPA T GS+T       G  T  A+T G  +        +  ++T 
Sbjct: 841  SETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 899

Query: 342  TGTLTIPAPTRGTDMGTLTI---PAPTRDTDPGTLTIPAPTWGRSLFQHXHG-DAHYSST 397
             G+ T  A T G++  T +       T  T+   +T  + T   +      G +   +ST
Sbjct: 900  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 959

Query: 398  DTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTG-RSLFQHRHGEAHYSSTDKGHRHRDAHY 456
            +   LT  + T   ++     G    + T  G  +      G    + +  G     A  
Sbjct: 960  EGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASI 1019

Query: 457  SSTD------TGTLTIPAPTQGAHYSSTDT-GTLTIAAPTRGTDMWMLTIPALTRGRSLF 509
              ++      TG+ T    T G   + T T G+ T    T G++    T    T   +  
Sbjct: 1020 EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE---TTAVYTTGSETTT 1076

Query: 510  QHRHGDAHYCSTDMGRSLLQHQHGDAHYSSID-AGTLTIPAPTRGAHYSST-DTGTLTIA 567
                G      +  G         D   +++  +G+ T  A T G+  ++   TG+ T  
Sbjct: 1077 TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT 1136

Query: 568  APTRG 572
            A T G
Sbjct: 1137 ASTEG 1141


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 67/305 (21%), Positives = 112/305 (36%), Gaps = 26/305 (8%)

Query: 290  SDTRALPTDTGTLTIPAPTRGSDT-------GMLTVPATTRGC-SLFQHRHGDDHYSSTD 341
            S+T  + T  G+ TIPA T GS+T       G  T  A+T G  +        +  ++T 
Sbjct: 820  SETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 342  TGTLTIPAPTRGTDMGTLTI---PAPTRDTDPGTLTIPAPTWGRSLFQHXHG-DAHYSST 397
             G+ T  A T G++  T +       T  T+   +T  + T   +      G +   +ST
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 398  DTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTG-RSLFQHRHGEAHYSSTDKGHRHRDAHY 456
            +   LT  + T   ++     G    + T  G  +      G    + +  G     A  
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASI 998

Query: 457  SSTD------TGTLTIPAPTQGAHYSSTDT-GTLTIAAPTRGTDMWMLTIPALTRGRSLF 509
              ++      TG+ T    T G   + T T G+ T    T G++    T    T   +  
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE---TTAVYTTGSETTT 1055

Query: 510  QHRHGDAHYCSTDMGRSLLQHQHGDAHYSSID-AGTLTIPAPTRGAHYSST-DTGTLTIA 567
                G      +  G         D   +++  +G+ T  A T G+  ++   TG+ T  
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT 1115

Query: 568  APTRG 572
            A T G
Sbjct: 1116 ASTEG 1120


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 67/305 (21%), Positives = 112/305 (36%), Gaps = 26/305 (8%)

Query: 290  SDTRALPTDTGTLTIPAPTRGSDT-------GMLTVPATTRGC-SLFQHRHGDDHYSSTD 341
            S+T  + T  G+ TIPA T GS+T       G  T  A+T G  +        +  ++T 
Sbjct: 820  SETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 342  TGTLTIPAPTRGTDMGTLTI---PAPTRDTDPGTLTIPAPTWGRSLFQHXHG-DAHYSST 397
             G+ T  A T G++  T +       T  T+   +T  + T   +      G +   +ST
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 398  DTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTG-RSLFQHRHGEAHYSSTDKGHRHRDAHY 456
            +   LT  + T   ++     G    + T  G  +      G    + +  G     A  
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASI 998

Query: 457  SSTD------TGTLTIPAPTQGAHYSSTDT-GTLTIAAPTRGTDMWMLTIPALTRGRSLF 509
              ++      TG+ T    T G   + T T G+ T    T G++    T    T   +  
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE---TTAVYTTGSETTT 1055

Query: 510  QHRHGDAHYCSTDMGRSLLQHQHGDAHYSSID-AGTLTIPAPTRGAHYSST-DTGTLTIA 567
                G      +  G         D   +++  +G+ T  A T G+  ++   TG+ T  
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT 1115

Query: 568  APTRG 572
            A T G
Sbjct: 1116 ASTEG 1120


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 67/305 (21%), Positives = 112/305 (36%), Gaps = 26/305 (8%)

Query: 290  SDTRALPTDTGTLTIPAPTRGSDT-------GMLTVPATTRGC-SLFQHRHGDDHYSSTD 341
            S+T  + T  G+ TIPA T GS+T       G  T  A+T G  +        +  ++T 
Sbjct: 820  SETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 342  TGTLTIPAPTRGTDMGTLTI---PAPTRDTDPGTLTIPAPTWGRSLFQHXHG-DAHYSST 397
             G+ T  A T G++  T +       T  T+   +T  + T   +      G +   +ST
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 398  DTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTG-RSLFQHRHGEAHYSSTDKGHRHRDAHY 456
            +   LT  + T   ++     G    + T  G  +      G    + +  G     A  
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASI 998

Query: 457  SSTD------TGTLTIPAPTQGAHYSSTDT-GTLTIAAPTRGTDMWMLTIPALTRGRSLF 509
              ++      TG+ T    T G   + T T G+ T    T G++    T    T   +  
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE---TTAVYTTGSETTT 1055

Query: 510  QHRHGDAHYCSTDMGRSLLQHQHGDAHYSSID-AGTLTIPAPTRGAHYSST-DTGTLTIA 567
                G      +  G         D   +++  +G+ T  A T G+  ++   TG+ T  
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT 1115

Query: 568  APTRG 572
            A T G
Sbjct: 1116 ASTEG 1120


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 67/305 (21%), Positives = 112/305 (36%), Gaps = 26/305 (8%)

Query: 290  SDTRALPTDTGTLTIPAPTRGSDT-------GMLTVPATTRGC-SLFQHRHGDDHYSSTD 341
            S+T  + T  G+ TIPA T GS+T       G  T  A+T G  +        +  ++T 
Sbjct: 820  SETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 342  TGTLTIPAPTRGTDMGTLTI---PAPTRDTDPGTLTIPAPTWGRSLFQHXHG-DAHYSST 397
             G+ T  A T G++  T +       T  T+   +T  + T   +      G +   +ST
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 398  DTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTG-RSLFQHRHGEAHYSSTDKGHRHRDAHY 456
            +   LT  + T   ++     G    + T  G  +      G    + +  G     A  
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASI 998

Query: 457  SSTD------TGTLTIPAPTQGAHYSSTDT-GTLTIAAPTRGTDMWMLTIPALTRGRSLF 509
              ++      TG+ T    T G   + T T G+ T    T G++    T    T   +  
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE---TTAVYTTGSETTT 1055

Query: 510  QHRHGDAHYCSTDMGRSLLQHQHGDAHYSSID-AGTLTIPAPTRGAHYSST-DTGTLTIA 567
                G      +  G         D   +++  +G+ T  A T G+  ++   TG+ T  
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT 1115

Query: 568  APTRG 572
            A T G
Sbjct: 1116 ASTEG 1120


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 67/305 (21%), Positives = 112/305 (36%), Gaps = 26/305 (8%)

Query: 290  SDTRALPTDTGTLTIPAPTRGSDT-------GMLTVPATTRGC-SLFQHRHGDDHYSSTD 341
            S+T  + T  G+ TIPA T GS+T       G  T  A+T G  +        +  ++T 
Sbjct: 820  SETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 342  TGTLTIPAPTRGTDMGTLTI---PAPTRDTDPGTLTIPAPTWGRSLFQHXHG-DAHYSST 397
             G+ T  A T G++  T +       T  T+   +T  + T   +      G +   +ST
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 398  DTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTG-RSLFQHRHGEAHYSSTDKGHRHRDAHY 456
            +   LT  + T   ++     G    + T  G  +      G    + +  G     A  
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASI 998

Query: 457  SSTD------TGTLTIPAPTQGAHYSSTDT-GTLTIAAPTRGTDMWMLTIPALTRGRSLF 509
              ++      TG+ T    T G   + T T G+ T    T G++    T    T   +  
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE---TTAVYTTGSETTT 1055

Query: 510  QHRHGDAHYCSTDMGRSLLQHQHGDAHYSSID-AGTLTIPAPTRGAHYSST-DTGTLTIA 567
                G      +  G         D   +++  +G+ T  A T G+  ++   TG+ T  
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT 1115

Query: 568  APTRG 572
            A T G
Sbjct: 1116 ASTEG 1120


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 67/305 (21%), Positives = 112/305 (36%), Gaps = 26/305 (8%)

Query: 290  SDTRALPTDTGTLTIPAPTRGSDT-------GMLTVPATTRGC-SLFQHRHGDDHYSSTD 341
            S+T  + T  G+ TIPA T GS+T       G  T  A+T G  +        +  ++T 
Sbjct: 820  SETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 342  TGTLTIPAPTRGTDMGTLTI---PAPTRDTDPGTLTIPAPTWGRSLFQHXHG-DAHYSST 397
             G+ T  A T G++  T +       T  T+   +T  + T   +      G +   +ST
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 398  DTGTLTIPAPTRGRSLFQHXHGDAHYSSTNTG-RSLFQHRHGEAHYSSTDKGHRHRDAHY 456
            +   LT  + T   ++     G    + T  G  +      G    + +  G     A  
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASI 998

Query: 457  SSTD------TGTLTIPAPTQGAHYSSTDT-GTLTIAAPTRGTDMWMLTIPALTRGRSLF 509
              ++      TG+ T    T G   + T T G+ T    T G++    T    T   +  
Sbjct: 999  EGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE---TTAVYTTGSETTT 1055

Query: 510  QHRHGDAHYCSTDMGRSLLQHQHGDAHYSSID-AGTLTIPAPTRGAHYSST-DTGTLTIA 567
                G      +  G         D   +++  +G+ T  A T G+  ++   TG+ T  
Sbjct: 1056 TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTT 1115

Query: 568  APTRG 572
            A T G
Sbjct: 1116 ASTEG 1120


>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1A isoform 2 [Homo sapiens]
          Length = 754

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 44/183 (24%), Positives = 67/183 (36%), Gaps = 17/183 (9%)

Query: 601 STDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRP 660
           S  +G     +  S   +GT   + R R  P  QHRH   H ++       +   T    
Sbjct: 493 SQSSGTTSSTSSSSGGSSGTSN-SGRARSDPTHQHRHSGGHFTA---AVQAMDCETHSPQ 548

Query: 661 LFQHRHGDAHYSSTDTGT-LTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDT 719
           + Q       +S T+  T +T+       + F   H AP   ++   H HG++  S    
Sbjct: 549 VRQQFPAPLGWSGTEAPTQVTVETHPVQETTF---HVAP--QQNALHHHHGNS--SHHHH 601

Query: 720 GHRHGDAHYSSTDVGTLTIP----APTRGRSLFQHQH-GDVHYSSTDRGMLTIPAPTRGT 774
            H H   H+    +G  T P    +PT   S       G  H+S T     T  + T  +
Sbjct: 602 HHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSS 661

Query: 775 DTG 777
            TG
Sbjct: 662 STG 664



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 61/283 (21%), Positives = 97/283 (34%), Gaps = 53/283 (18%)

Query: 758 SSTDRGMLTIPAPTRGTDTGTLTIPALTWGRS-------------LLQHRHGDAHYCSTD 804
           ++T   + T PA  +   +GT +  + + G S               QHRH   H+ +  
Sbjct: 478 TNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGHFTAA- 536

Query: 805 MGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGT-LTI-----------AAPTRGRSLLQHQ 852
                +   T    + Q       +S T+  T +T+            AP +  + L H 
Sbjct: 537 --VQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQ--NALHHH 592

Query: 853 HGAPTWGRSQFQHRHGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQH-RHGNTHYS 911
           HG  +       H H   H+     G  T P    + T  + T+      H  H  T  S
Sbjct: 593 HGNSS--HHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLS 650

Query: 912 STDTGTLTITAPT--RGGSLFQHR-----------HGEAHYSSTDTGTPTNPAPTQGRPL 958
           S+ T + T ++ T  +G   +Q+R           +G    + T    P       G P 
Sbjct: 651 SSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPT 710

Query: 959 FQH--RHGDAHYSSTDTGH---RHGDAHYTSTDMGTLTIPAPI 996
           +Q     G AHY +   GH   R G     S   G     +P+
Sbjct: 711 YQFSANTGPAHYMT--EGHLTMRQGADREESPMTGVCVQQSPV 751



 Score = 30.8 bits (68), Expect = 7.3
 Identities = 54/254 (21%), Positives = 82/254 (32%), Gaps = 48/254 (18%)

Query: 457 SSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDA 516
           ++T     T PA  Q +  S T + T + +  + GT           R     QHRH   
Sbjct: 478 TNTSNSVSTSPAMEQ-SQSSGTTSSTSSSSGGSSGTSN-----SGRARSDPTHQHRHSGG 531

Query: 517 HYCSTDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLF 576
           H+ +         H            G     APT+    +     T    AP +     
Sbjct: 532 HFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNA--L 589

Query: 577 QHRHGAPTRGCSLFQHQH------------------GDTHYSSTDTGHRHGDAHYSSTDT 618
            H HG  +       H H                    T+ SST      G +H+S T  
Sbjct: 590 HHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSL 649

Query: 619 GTLTIAART-------RGRPLFQHRHGDAH------NSSTDTGTLTIAARTQ------GR 659
            + T ++ T       +G   +Q+R   A+      N + D   LT+ +  +      G 
Sbjct: 650 SSSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDV-NLTVYSNPRQETGIAGH 708

Query: 660 PLFQH--RHGDAHY 671
           P +Q     G AHY
Sbjct: 709 PTYQFSANTGPAHY 722


>gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated
           kinase 1A isoform 1 [Homo sapiens]
          Length = 763

 Score = 37.0 bits (84), Expect = 0.10
 Identities = 44/183 (24%), Positives = 67/183 (36%), Gaps = 17/183 (9%)

Query: 601 STDTGHRHGDAHYSSTDTGTLTIAARTRGRPLFQHRHGDAHNSSTDTGTLTIAARTQGRP 660
           S  +G     +  S   +GT   + R R  P  QHRH   H ++       +   T    
Sbjct: 502 SQSSGTTSSTSSSSGGSSGTSN-SGRARSDPTHQHRHSGGHFTA---AVQAMDCETHSPQ 557

Query: 661 LFQHRHGDAHYSSTDTGT-LTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDT 719
           + Q       +S T+  T +T+       + F   H AP   ++   H HG++  S    
Sbjct: 558 VRQQFPAPLGWSGTEAPTQVTVETHPVQETTF---HVAP--QQNALHHHHGNS--SHHHH 610

Query: 720 GHRHGDAHYSSTDVGTLTIP----APTRGRSLFQHQH-GDVHYSSTDRGMLTIPAPTRGT 774
            H H   H+    +G  T P    +PT   S       G  H+S T     T  + T  +
Sbjct: 611 HHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSS 670

Query: 775 DTG 777
            TG
Sbjct: 671 STG 673



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 61/283 (21%), Positives = 97/283 (34%), Gaps = 53/283 (18%)

Query: 758 SSTDRGMLTIPAPTRGTDTGTLTIPALTWGRS-------------LLQHRHGDAHYCSTD 804
           ++T   + T PA  +   +GT +  + + G S               QHRH   H+ +  
Sbjct: 487 TNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGHFTAA- 545

Query: 805 MGTLTIPAPTQGRSLFQHQHGDAHYSSTDTGT-LTI-----------AAPTRGRSLLQHQ 852
                +   T    + Q       +S T+  T +T+            AP +  + L H 
Sbjct: 546 --VQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQ--NALHHH 601

Query: 853 HGAPTWGRSQFQHRHGDTHYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQH-RHGNTHYS 911
           HG  +       H H   H+     G  T P    + T  + T+      H  H  T  S
Sbjct: 602 HGNSS--HHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLS 659

Query: 912 STDTGTLTITAPT--RGGSLFQHR-----------HGEAHYSSTDTGTPTNPAPTQGRPL 958
           S+ T + T ++ T  +G   +Q+R           +G    + T    P       G P 
Sbjct: 660 SSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPT 719

Query: 959 FQH--RHGDAHYSSTDTGH---RHGDAHYTSTDMGTLTIPAPI 996
           +Q     G AHY +   GH   R G     S   G     +P+
Sbjct: 720 YQFSANTGPAHYMT--EGHLTMRQGADREESPMTGVCVQQSPV 760



 Score = 30.8 bits (68), Expect = 7.3
 Identities = 54/254 (21%), Positives = 82/254 (32%), Gaps = 48/254 (18%)

Query: 457 SSTDTGTLTIPAPTQGAHYSSTDTGTLTIAAPTRGTDMWMLTIPALTRGRSLFQHRHGDA 516
           ++T     T PA  Q +  S T + T + +  + GT           R     QHRH   
Sbjct: 487 TNTSNSVSTSPAMEQ-SQSSGTTSSTSSSSGGSSGTSN-----SGRARSDPTHQHRHSGG 540

Query: 517 HYCSTDMGRSLLQHQHGDAHYSSIDAGTLTIPAPTRGAHYSSTDTGTLTIAAPTRGCSLF 576
           H+ +         H            G     APT+    +     T    AP +     
Sbjct: 541 HFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNA--L 598

Query: 577 QHRHGAPTRGCSLFQHQH------------------GDTHYSSTDTGHRHGDAHYSSTDT 618
            H HG  +       H H                    T+ SST      G +H+S T  
Sbjct: 599 HHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSL 658

Query: 619 GTLTIAART-------RGRPLFQHRHGDAH------NSSTDTGTLTIAARTQ------GR 659
            + T ++ T       +G   +Q+R   A+      N + D   LT+ +  +      G 
Sbjct: 659 SSSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDV-NLTVYSNPRQETGIAGH 717

Query: 660 PLFQH--RHGDAHY 671
           P +Q     G AHY
Sbjct: 718 PTYQFSANTGPAHY 731


>gi|56788366 phosphatidylinositol-binding clathrin assembly protein
           isoform 1 [Homo sapiens]
          Length = 652

 Score = 35.0 bits (79), Expect = 0.39
 Identities = 44/182 (24%), Positives = 65/182 (35%), Gaps = 13/182 (7%)

Query: 235 KHSRDARVRIRGVTVVGAAQGSVATHSWEAKDGPRATGPAQPKIQARFLLLQSHHSDTRA 294
           K  +D+    R  T+  A     +T     K   R    A  + QAR   L+       A
Sbjct: 288 KKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELA 347

Query: 295 LPTDTGTLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGT 354
               T   T  +P   S  G++T PA      +F      +  S      L +  PT   
Sbjct: 348 KKPHTSLTTAASPVSTSAGGIMTAPA----IDIFSTPSSSNSTSKLPNDLLDLQQPTFHP 403

Query: 355 DMGTLTIPAPTRDT--DPGTLTIPA-----PTWGRSLFQHXHGDAHYS-STDTGTLTIPA 406
            +  ++  +    T  DP + T+ A     P+    L +   GD H S S+D  T T   
Sbjct: 404 SVHPMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTK-SSGDVHLSISSDVSTFTTRT 462

Query: 407 PT 408
           PT
Sbjct: 463 PT 464


>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
          Length = 456

 Score = 35.0 bits (79), Expect = 0.39
 Identities = 55/249 (22%), Positives = 82/249 (32%), Gaps = 29/249 (11%)

Query: 248 TVVGAAQGSVATHSWEAKDGPRAT-GPAQ---PKIQARFLLLQSHHSDTRALPTDTGTLT 303
           T  G  + S   HS  +   PR T  PA    P +Q      Q+H + T   P+   T T
Sbjct: 151 TSSGIVEASTRVHS--STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTAT 208

Query: 304 IPAPTR--------GSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGTD 355
            P             + T      +TT G     H      + S+   + T P+    T 
Sbjct: 209 APVEESTTYHRSPGSTPTTHFPASSTTSG-----HSEKSTIFHSSPDASGTTPSSAHSTT 263

Query: 356 MGTLTIPAPTRDTDPG---TLTIPAPTWGRSLFQH-XHGDAHYSSTDTGTLTIPAPTRGR 411
            G ++  + T  + PG   T   P  T    L Q      +   ST+    T P+P    
Sbjct: 264 SG-VSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTT 322

Query: 412 SLFQHXHGDAHYSSTNTGRSLFQHRHGEAHYSSTDKGHRHRDAHYSSTDTGTLTIPAPTQ 471
           +         H   ++T  +     H  A  ++  +       H S   T T  +P  T 
Sbjct: 323 AAPVEVSTTYHSRPSSTPTT-----HFSASSTTLGRSEESTTVHSSPGSTETTALPGSTT 377

Query: 472 GAHYSSTDT 480
            A  S   T
Sbjct: 378 TAGLSEKST 386



 Score = 33.9 bits (76), Expect = 0.86
 Identities = 77/363 (21%), Positives = 119/363 (32%), Gaps = 48/363 (13%)

Query: 677  GTLTIPAPTRGRSLFQHRHGAPIWGRSLFQHRHGDAHYSSTDTGHRHGDAHYSSTDVGTL 736
            G+ T P  +   + F     +P    S            ST +  R G  H ++    T 
Sbjct: 8    GSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTT 67

Query: 737  TIPAPTRGRSLFQHQHGDVHYSSTDRGMLTIPAPTRGTDTGTLTIPALTWGRSLLQHRHG 796
            T P  +R  +      G     STD  +L     T G    + T            H   
Sbjct: 68   T-PGLSRHSTTSHSSPG-----STDTTLLPASTTTSGPSQESTT-----------SHSSP 110

Query: 797  DAHYCSTDMGTLTIPAPTQGRSLFQHQHGDAH---YSSTDTGTLTIAAPTRGRSLLQHQH 853
             +   +   G+ T  +  Q  + F    G  H   +  + T +  + A TR  S      
Sbjct: 111  GSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPR 170

Query: 854  GAPTWGRSQFQHRHGD-THYCSNDTGTHTIPAPTGTLTIPAPTRGRSLFQHRHGN---TH 909
               +   S      G+ T + ++   THT P+P  T T  AP    + +    G+   TH
Sbjct: 171  TTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTAT--APVEESTTYHRSPGSTPTTH 228

Query: 910  Y--SSTDTG-----TLTITAPTRGGSLFQHRHGEAHYSSTDTGTPTNPAPTQGRPLFQHR 962
            +  SST +G     T+  ++P   G+     H      ST +G     + +  +P     
Sbjct: 229  FPASSTTSGHSEKSTIFHSSPDASGTTPSSAH------STTSGVSEESSTSHSQP--GST 280

Query: 963  HGDAHYSSTDTG-------HRHGDAHYTSTDMGTLTIPAPIQGRPLFQHRHGDAHYSSTD 1015
            H  A   ST T          H     T   + T   P      P+       +  SST 
Sbjct: 281  HTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTP 340

Query: 1016 TGH 1018
            T H
Sbjct: 341  TTH 343


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,542,657
Number of Sequences: 37866
Number of extensions: 2618678
Number of successful extensions: 8236
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 6687
Number of HSP's gapped (non-prelim): 491
length of query: 1090
length of database: 18,247,518
effective HSP length: 113
effective length of query: 977
effective length of database: 13,968,660
effective search space: 13647380820
effective search space used: 13647380820
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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