BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] (238 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 491 e-139 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 376 e-104 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 281 5e-76 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 226 1e-59 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 226 2e-59 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 226 2e-59 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 222 2e-58 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 218 5e-57 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 216 2e-56 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 202 3e-52 gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 172 2e-43 gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 140 1e-33 gi|148746195 trichohyalin [Homo sapiens] 123 2e-28 gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub... 113 2e-25 gi|154937324 hypothetical protein LOC440295 [Homo sapiens] 113 2e-25 gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap... 112 2e-25 gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 104 6e-23 gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 104 8e-23 gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 104 8e-23 gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 103 1e-22 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 100 2e-21 gi|221219020 NYD-SP11 protein [Homo sapiens] 99 4e-21 gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 95 6e-20 gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 95 6e-20 gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 95 6e-20 gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 95 6e-20 gi|95147555 microtubule-associated protein 1A [Homo sapiens] 94 8e-20 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 91 7e-19 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 91 9e-19 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 91 9e-19 >gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] Length = 238 Score = 491 bits (1265), Expect = e-139 Identities = 238/238 (100%), Positives = 238/238 (100%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM Sbjct: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE Sbjct: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 Query: 181 PAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI 238 PAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI Sbjct: 181 PAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI 238 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 376 bits (965), Expect = e-104 Identities = 201/274 (73%), Positives = 222/274 (81%), Gaps = 37/274 (13%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615 Query: 61 EKMWEQEEK---------MWEQ-QRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEK 108 EKMWEQEE+ MWEQ +++ EQ+EKMWEQ+E++RE+EE+MREQ KM Q EK Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 675 Query: 109 MR---EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 165 MR EK + QEEKM+EQEEKM+ QEE MW QEEKM QEEKMW QEE MRE+EE++R+Q Sbjct: 676 MREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE-MREKEERIRDQ 734 Query: 166 EEKMQGQ----EEKMRD-----------------VEPAGGEAGEGSPQDNPTAQEIMQLF 204 +EKMQ + EE+ + VEPAGGEAGEGSPQDNPTAQEIMQLF Sbjct: 735 KEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEGSPQDNPTAQEIMQLF 794 Query: 205 CGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI 238 CGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI Sbjct: 795 CGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI 828 Score = 259 bits (662), Expect = 1e-69 Identities = 157/293 (53%), Positives = 171/293 (58%), Gaps = 113/293 (38%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ------------EEK 48 M+EEER+REREKKMREEEE MREQEEKMQ+QEE M EQEEK W+Q +EK Sbjct: 388 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 447 Query: 49 MQEQEEKMWEQEEK------MWEQEEKMWEQQRLPE---------------------QKE 81 MQEQEEK+WEQEEK MW QE+KMW Q+++ E Q+E Sbjct: 448 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 507 Query: 82 KMWEQDERLREKEERMREQ-KMWQQVEKMREKKKT------------------------- 115 +MWEQDERLREKEERMREQ KMWQQ EKMRE+KKT Sbjct: 508 RMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREK 567 Query: 116 -----------QEEKMQEQEE-------------------------------------KM 127 QEEKMQEQEE KM Sbjct: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627 Query: 128 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR+ E Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680 Score = 243 bits (621), Expect = 8e-65 Identities = 131/221 (59%), Positives = 166/221 (75%), Gaps = 43/221 (19%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+E+R+RE+EK++RE+E+ +REQ+ K++EQEE+M+EQEEKMWEQEEKM+EQEEKMW QEE Sbjct: 280 RQEKRLREQEKELREQEKELREQK-KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338 Query: 62 KMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMRE-------- 111 ++WEQE++M EQ Q++ +Q+E+MWEQDERLREKEERMREQ KMW+Q EKM+E Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRERE 398 Query: 112 -KKKTQEEKMQEQEEKMQEQEEMMWEQE-------------------EKMQEQEEKMWEQ 151 K + +EE M+EQEEKMQ+QEE MWEQE EKMQEQEEK+WEQ Sbjct: 399 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 458 Query: 152 EEKMREQE------------EKMREQEEKMQGQEEKMRDVE 180 EEK+R+QE EKMREQE++M QEEKMRD E Sbjct: 459 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 499 Score = 226 bits (576), Expect = 1e-59 Identities = 123/193 (63%), Positives = 157/193 (81%), Gaps = 18/193 (9%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMRE------QEEKMWEQEEKMQEQE--- 53 +EERM E+++++RE+EE MREQ+ KM +QEEKMRE QE+K W+QEEKM+E+E Sbjct: 505 QEERMWEQDERLREKEERMREQK-KMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563 Query: 54 ---EKMWEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERM--REQKMWQQVE 107 +KM E+EE M EQEEKM EQ+ ++ EQ+EKMWEQ+E+++E+EE+M +E+KMW+Q E Sbjct: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 623 Query: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167 + +K + QEE M EQEEKMQEQEE MWEQEEKM+EQEEKM EQEEKM+ QEEKMREQEE Sbjct: 624 E--DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681 Query: 168 KMQGQEEKMRDVE 180 KMQGQEEKMR+ E Sbjct: 682 KMQGQEEKMREQE 694 Score = 223 bits (567), Expect = 1e-58 Identities = 122/180 (67%), Positives = 153/180 (85%), Gaps = 11/180 (6%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 ++EE+MRE EKK +E+E+ +QEEKM+E EE+MRE+E+KM E+EE M+EQEEKM EQEE Sbjct: 531 QQEEKMRE-EKKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEE 588 Query: 62 KMWEQEEKMWEQ-QRLPEQKEKMWEQDERL--REKEERMREQK--MWQQVEKMREKKKTQ 116 KM EQEEKMWEQ +++ EQ+EKMWEQ+E++ +E+E++M+EQ+ MW+Q EKM+E Q Sbjct: 589 KMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQE----Q 644 Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 EEKM EQEEKM+EQEE M EQEEKMQ QEEKM EQEEKM+ QEEKMREQEEKM+GQEEKM Sbjct: 645 EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKM 704 Score = 217 bits (552), Expect = 8e-57 Identities = 122/228 (53%), Positives = 161/228 (70%), Gaps = 51/228 (22%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE------KMWEQEEKMQE---- 51 R+EER+ E+EK+MRE+E+ MR+QEE+M EQ+E++RE+EE KMWEQEEKMQE Sbjct: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394 Query: 52 ----------------QEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMW------EQDER 89 QEEKM +QEE MWEQEEK W+QQRLPEQKEK+W EQ+E+ Sbjct: 395 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454 Query: 90 LREKEERMREQ--------KMWQQVEKMREKKK---TQEEKMQEQEEKMQEQEEMMWEQE 138 + E+EE++R+Q KMW+Q EKMRE++ QEEKM++QE+KM +QEE MWEQ+ Sbjct: 455 IWEQEEKIRDQEEMWGQEKKMWRQ-EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD 513 Query: 139 EKMQEQEE------KMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 E+++E+EE KMW+QEEKMRE E+K +EQE+K QEEKMR+ E Sbjct: 514 ERLREKEERMREQKKMWQQEEKMRE-EKKTQEQEKKTWDQEEKMREEE 560 Score = 177 bits (449), Expect = 7e-45 Identities = 102/194 (52%), Positives = 142/194 (73%), Gaps = 25/194 (12%) Query: 1 MREEERMREREKKMREE------EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 54 ++E +R ER K + + +E M QEE+++EQE+K+R+QEEKMW QEE+++EQE Sbjct: 210 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEG 269 Query: 55 KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERL------REKEERMREQ--KMWQQV 106 KM EQEEKM QE+ RL EQ++++ EQ++ L RE+EE+M+EQ KMW+Q Sbjct: 270 KMREQEEKMRRQEK------RLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323 Query: 107 EKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 166 EKMRE QEEKM QEE++ EQE+ M EQE+KM++QEE+MWEQ+E++RE+EE+MREQ Sbjct: 324 EKMRE----QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ- 378 Query: 167 EKMQGQEEKMRDVE 180 EKM QEEKM++ E Sbjct: 379 EKMWEQEEKMQEEE 392 Score = 157 bits (397), Expect = 8e-39 Identities = 87/180 (48%), Positives = 130/180 (72%), Gaps = 14/180 (7%) Query: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 68 E +KK E +E +R E + E + ++E + K+ E+ + + Q + QEE MW QEE Sbjct: 184 ELKKKNAELQEKLRLAESEKSEIQLNVKELKRKL-ERAKFLLPQVQTNTLQEE-MWRQEE 241 Query: 69 KMWEQQR-LPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKK---------TQ 116 ++ EQ++ + +Q+EKMW Q+ERLRE+E +MREQ KM +Q +++RE++K + Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301 Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 ++K++EQEE+MQEQEE MWEQEEKM+EQEEKMW QEE++ EQE++MREQE+KM+ QEE+M Sbjct: 302 QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 361 Score = 95.1 bits (235), Expect = 5e-20 Identities = 48/119 (40%), Positives = 85/119 (71%), Gaps = 1/119 (0%) Query: 61 EKMWEQEEKMWEQQRLPE-QKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119 E++ ++ ++ E+ RL E +K ++ + L+ K ER + Q ++E+ QEE+ Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242 Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178 ++EQE+K+++QEE MW QEE+++EQE KM EQEEKMR QE+++REQE++++ QE+++R+ Sbjct: 243 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301 Score = 80.9 bits (198), Expect = 9e-16 Identities = 47/128 (36%), Positives = 72/128 (56%), Gaps = 7/128 (5%) Query: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119 EE E++ E R E++ +++ L+EK +K Q+ K+K + K Sbjct: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK 221 Query: 120 MQEQEEKMQEQEEMMWEQEEKMQE-------QEEKMWEQEEKMREQEEKMREQEEKMQGQ 172 + + +E MW QEE+++E QEEKMW QEE++REQE KMREQEEKM+ Q Sbjct: 222 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQ 281 Query: 173 EEKMRDVE 180 E+++R+ E Sbjct: 282 EKRLREQE 289 Score = 51.6 bits (122), Expect = 6e-07 Identities = 32/117 (27%), Positives = 63/117 (53%), Gaps = 1/117 (0%) Query: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123 W ++ + ++ E+ E EE ++ Q+ ++ E +K++ + ++ Sbjct: 153 WHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKE 212 Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 ++ E+ + + Q + QEE QEE++REQE+K+R+QEEKM QEE++R+ E Sbjct: 213 LKRKLERAKFLLPQVQTNTLQEEMWR-QEEELREQEKKIRKQEEKMWRQEERLREQE 268 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 281 bits (718), Expect = 5e-76 Identities = 154/238 (64%), Positives = 170/238 (71%), Gaps = 59/238 (24%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 MREEERMREREKKMREEEEMMREQEEKMQEQEEKM+EQEEKMWEQEEKMQEQEEKMWEQE Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWE-----QDERLREKEERM------------REQKMW 103 EKMWEQEEKMWEQQRLPEQKEK+WE + E+++E+EE++ +E+K W Sbjct: 645 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTW 704 Query: 104 QQVEKMREKK----------------KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEK 147 Q EKMRE++ + QEEKMQEQEEKMQEQEE MWEQEEKM EQEEK Sbjct: 705 DQ-EKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763 Query: 148 M-------------------------WEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 M WEQEEKMR+QEEKMR QEEKM+GQEEKMR E Sbjct: 764 MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821 Score = 248 bits (633), Expect = 3e-66 Identities = 134/185 (72%), Positives = 155/185 (83%), Gaps = 11/185 (5%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 MREEE MREREKKMREEEEMMREQEEKMQEQEEKM+EQEE+MWEQEEKM EQEEKMWEQ Sbjct: 709 MREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQ- 767 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMR--EQKMWQQVEKMR---EKKKT 115 +++ EQ+EK+WE +++ EQ EK+WEQ+E++R++EE+MR E+KM Q EKMR EK Sbjct: 768 QRLPEQKEKLWEHEKMQEQ-EKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWG 826 Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQE----QEEKMWEQEEKMREQEEKMREQEEKMQG 171 QEEKM QEEKM QEE MW QEEKM+E QEEKM EQEEKMR QEEKMREQEEKM+G Sbjct: 827 QEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRG 886 Query: 172 QEEKM 176 QEEK+ Sbjct: 887 QEEKI 891 Score = 245 bits (625), Expect = 3e-65 Identities = 128/209 (61%), Positives = 159/209 (76%), Gaps = 33/209 (15%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE------------EK 48 M+EEER+REREKKMREEEE MREQEEKMQ+QEE M EQEEK W+Q+ EK Sbjct: 446 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 505 Query: 49 MQEQEEKMWEQEEK------MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERM----- 97 MQEQEEK+WEQEEK MW QE+KMW Q+++ EQ+++MWEQ+E++R++E++M Sbjct: 506 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 565 Query: 98 --------REQKMWQQVEKMREKK--KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEK 147 +E+K W Q EKMRE++ + +E+KM+E+EE M+EQEE M EQEEKMQEQEEK Sbjct: 566 RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEK 625 Query: 148 MWEQEEKMREQEEKMREQEEKMQGQEEKM 176 MWEQEEKM+EQEEKM EQEEKM QEEKM Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654 Score = 244 bits (622), Expect = 6e-65 Identities = 133/227 (58%), Positives = 172/227 (75%), Gaps = 30/227 (13%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+E+R+RE+EK++RE+E+ +REQ+E ++EQEE+M+EQEEKMWEQEEKM+EQEEKMW QEE Sbjct: 318 RQEKRLREQEKELREQEKELREQKE-LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 376 Query: 62 KMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMREKKK----- 114 ++WEQE++M EQ Q++ +Q+E+MWEQDERLREKEERMREQ KMW+QVEKMRE+KK Sbjct: 377 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQE 436 Query: 115 ----TQEEKMQEQ------EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ------ 158 QEEKMQE+ E+KM+E+EE M EQEEKMQ+QEE MWEQEEK +Q Sbjct: 437 KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496 Query: 159 ------EEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199 +EKM+EQEEK+ QEEK+RD E G+ + Q+ QE Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543 Score = 241 bits (614), Expect = 5e-64 Identities = 127/189 (67%), Positives = 148/189 (78%), Gaps = 12/189 (6%) Query: 4 EERMREREKK-----MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 58 E++ +E+EKK EEE MRE+E+KM+E+EE MREQEEKM EQEEKMQEQEE+MWE Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWE 752 Query: 59 QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR---EKKKT 115 QEEKMWEQEEKMWEQQRLPEQKEK+WE ++ +++ +E+KM Q EKMR EK + Sbjct: 753 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRG 812 Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE----QEEKMREQEEKMQG 171 QEEKM+ QEEKM QEE MW QEEKM QEEKMW QEEKM E QEEKMREQEEKM+G Sbjct: 813 QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRG 872 Query: 172 QEEKMRDVE 180 QEEKMR+ E Sbjct: 873 QEEKMREQE 881 Score = 236 bits (603), Expect = 1e-62 Identities = 132/193 (68%), Positives = 151/193 (78%), Gaps = 15/193 (7%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 +E+E+ ++KMREEE M RE+E+KM+E+EE MREQEEKM EQEEKMQEQEE+MWEQEE Sbjct: 697 QEQEKKTWDQEKMREEESM-REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE 755 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQD-----ERLREKEERMREQ--KMWQQVEKMR---E 111 KMWEQEEKMWEQQRLPEQKEK+WE + E++ E+EE+MR+Q KM Q EKMR E Sbjct: 756 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEE 815 Query: 112 KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE----QEEKMREQEEKMREQEE 167 K + QEEKM QEEKM QEE MW QEEKM QEEKM E QEEKMREQEEKMR QEE Sbjct: 816 KMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEE 875 Query: 168 KMQGQEEKMRDVE 180 KM+ QEEKMR E Sbjct: 876 KMREQEEKMRGQE 888 Score = 223 bits (567), Expect = 1e-58 Identities = 118/204 (57%), Positives = 159/204 (77%), Gaps = 30/204 (14%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 MREE++M+E+EKK R++EE M+E EE+++E+E+KMRE+EE M EQEEKMQ+QEE MWEQE Sbjct: 426 MREEKKMQEQEKKTRDQEEKMQE-EERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484 Query: 61 EKMW------EQEEKMWEQQRLPEQKEKMWEQDERLREKEERM-REQKMWQQVEKMREKK 113 EK W EQ+EK+WEQ+++ EQ+EK+WEQ+E++R++EE +E+KMW+Q EKMRE Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ-EKMRE-- 541 Query: 114 KTQEEKMQEQEEKMQEQEEMMWEQEEKM----QEQEEKMWEQEEK-------------MR 156 QE++M EQEEKM++QE+ MW+QEE+M QEQE+K W+QEEK MR Sbjct: 542 --QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599 Query: 157 EQEEKMREQEEKMQGQEEKMRDVE 180 E+EE MREQEEKMQ QEEKM++ E Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQE 623 Score = 211 bits (538), Expect = 3e-55 Identities = 115/222 (51%), Positives = 158/222 (71%), Gaps = 43/222 (19%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 +RE++ +RE+E++M+E+EE M EQEEKM+EQEEKM QEE++WEQE++M+EQE+KM +QE Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLR--------EKEERMREQKMWQQVEKMREK 112 E+MWEQ+E++ E++ ++EKMWEQ E++R EK+ R +E+KM Q+ E++RE+ Sbjct: 397 ERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKM-QEEERIRER 455 Query: 113 KK---TQEEKMQEQEEKMQEQEEMMWEQE-------------------EKMQEQEEKMWE 150 +K +EE M+EQEEKMQ+QEE MWEQE EKMQEQEEK+WE Sbjct: 456 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 515 Query: 151 QEEKMREQE------------EKMREQEEKMQGQEEKMRDVE 180 QEEK+R+QE EKMREQE++M QEEKMRD E Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 557 Score = 203 bits (517), Expect = 9e-53 Identities = 117/216 (54%), Positives = 157/216 (72%), Gaps = 37/216 (17%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKM----REQEEKMWEQEEKMQEQE--- 53 M +E+MRE+E +M E+EE MR+QE+KM +QEE+M +EQE+K W+QEEKM+E+E Sbjct: 533 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMR 592 Query: 54 ---EKMWEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERM--REQKMWQQVE 107 +KM E+EE M EQEEKM EQ+ ++ EQ+EKMWEQ+E+++E+EE+M +E+KMW+Q E Sbjct: 593 EREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 652 Query: 108 KMREKKKTQE--------EKMQEQEEKMQEQEEMMWEQ---EEKMQEQEEKMWEQ----- 151 KM E+++ E EKMQEQE KMQEQEE +WEQ E+K QEQE+K W+Q Sbjct: 653 KMWEQQRLPEQKEKLWEHEKMQEQE-KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE 711 Query: 152 -------EEKMREQEEKMREQEEKMQGQEEKMRDVE 180 E+KMRE+EE MREQEEKMQ QEEKM++ E Sbjct: 712 EESMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 747 Score = 181 bits (458), Expect = 6e-46 Identities = 104/206 (50%), Positives = 144/206 (69%), Gaps = 36/206 (17%) Query: 1 MREEERMREREKKMREE------EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 54 ++E +R ER K + + +E M QEE+++EQE+K+R+QEEKMW QEE+++EQE Sbjct: 248 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEG 307 Query: 55 KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERL------REKEERMREQ--KMWQQV 106 KM EQEEKMW QE+ RL EQ++++ EQ++ L RE+EE+M+EQ KMW+Q Sbjct: 308 KMREQEEKMWRQEK------RLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQE 361 Query: 107 EKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ- 165 EKMRE QEEKM QEE++ EQE+ M EQE+KM++QEE+MWEQ+E++RE+EE+MREQ Sbjct: 362 EKMRE----QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 417 Query: 166 -----------EEKMQGQEEKMRDVE 180 E+KMQ QE+K RD E Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQE 443 Score = 170 bits (431), Expect = 9e-43 Identities = 90/181 (49%), Positives = 131/181 (72%), Gaps = 13/181 (7%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 + E ++ +E K + E + + +E+M QEE++ EQE+K+++QEEKMW QEE Sbjct: 241 KSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEE 300 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK--KTQEEK 119 ++ EQE KM EQ+EKMW Q++RLRE+E+ +REQ+ +++RE+K + QEE+ Sbjct: 301 RLREQEGKM------REQEEKMWRQEKRLREQEKELREQE-----KELREQKELREQEEQ 349 Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDV 179 MQEQEEKM EQEE M EQEEKM QEE++WEQE++MREQE+KMR+QEE+M Q+E++R+ Sbjct: 350 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 409 Query: 180 E 180 E Sbjct: 410 E 410 Score = 159 bits (401), Expect = 3e-39 Identities = 81/185 (43%), Positives = 131/185 (70%), Gaps = 19/185 (10%) Query: 5 ERMREREKKMREEEEMMREQEEKMQ--EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 E ++++ +++E+ + ++ ++Q +E K + + K + + +E+MW QEE+ Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 280 Query: 63 MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKK------ 114 + EQE+K + +Q+EKMW Q+ERLRE+E +MREQ KMW+Q +++RE++K Sbjct: 281 LREQEKK------IRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQE 334 Query: 115 ---TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG 171 ++++++EQEE+MQEQEE MWEQEEKM+EQEEKMW QEE++ EQE++MREQE+KM+ Sbjct: 335 KELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 394 Query: 172 QEEKM 176 QEE+M Sbjct: 395 QEERM 399 Score = 99.8 bits (247), Expect = 2e-21 Identities = 62/152 (40%), Positives = 90/152 (59%), Gaps = 25/152 (16%) Query: 50 QEQEEKMWEQEEKM-WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEK 108 +E ++K E +EK+ + EK Q + E K K+ L + + +++MW+Q E+ Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 280 Query: 109 MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEK-------------- 154 +RE QE+K+++QEEKM QEE + EQE KM+EQEEKMW QE++ Sbjct: 281 LRE----QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336 Query: 155 ------MREQEEKMREQEEKMQGQEEKMRDVE 180 +REQEE+M+EQEEKM QEEKMR+ E Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEEKMREQE 368 Score = 79.3 bits (194), Expect = 3e-15 Identities = 47/128 (36%), Positives = 71/128 (55%), Gaps = 7/128 (5%) Query: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119 EE E++ E R E++ +++ L+EK +K Q+ K+K + K Sbjct: 200 EELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAK 259 Query: 120 MQEQEEKMQEQEEMMWEQEEKMQE-------QEEKMWEQEEKMREQEEKMREQEEKMQGQ 172 + + +E MW QEE+++E QEEKMW QEE++REQE KMREQEEKM Q Sbjct: 260 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQ 319 Query: 173 EEKMRDVE 180 E+++R+ E Sbjct: 320 EKRLREQE 327 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 226 bits (577), Expect = 1e-59 Identities = 116/188 (61%), Positives = 154/188 (81%), Gaps = 5/188 (2%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 ++EE+M +E+K++E EE ++EQEEK++EQEEKMR QEE MWE+EEKM+ QEE MWE+EE Sbjct: 285 QQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 344 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERM-REQKMWQQVEKMR---EKKKTQE 117 K+ E EEKM EQ+++ EQ+EK +++E++RE+E+R +E KMW+Q EK+R EK + QE Sbjct: 345 KIRELEEKMHEQEKIREQEEKR-QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 403 Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 E MQEQEEKM EQEE MWEQEE+MQEQEEKM QEEK+REQE+K+REQEEK++ QEE M+ Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 463 Query: 178 DVEPAGGE 185 + E GE Sbjct: 464 EQEEKMGE 471 Score = 224 bits (571), Expect = 5e-59 Identities = 120/183 (65%), Positives = 154/183 (84%), Gaps = 6/183 (3%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+EE++RE+E+K+RE+EEMM+EQEEKM EQEEKM EQEE+M EQEEKM+ QEEK+ EQE+ Sbjct: 387 RQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK 446 Query: 62 KMWEQEEKMWEQQRL-PEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKT--- 115 K+ EQEEK+ EQ+ + EQ+EKM EQ+ ++ E+E +M+EQ KM +Q EK+RE++K Sbjct: 447 KIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIRE 506 Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175 QEEK++EQEE MQEQEE MWEQEEKM EQEEKM EQEEKMR QEEKMREQE +++ QEEK Sbjct: 507 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566 Query: 176 MRD 178 M++ Sbjct: 567 MQE 569 Score = 221 bits (564), Expect = 3e-58 Identities = 119/181 (65%), Positives = 149/181 (82%), Gaps = 7/181 (3%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 +E +M +E+K+RE+EE +REQEE MQEQEEKM EQEEKMWEQEE+MQEQEEKM QEEK Sbjct: 381 QEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEK 440 Query: 63 MWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEEK 119 + EQE+K+ EQ+ ++ EQ+E M EQ+E++ E+E +M EQ KM +Q EKMR QEEK Sbjct: 441 IREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR----QEEK 496 Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDV 179 ++EQE+K++EQEE + EQEE MQEQEEKMWEQEEKM EQEEKM+EQEEKM+ QEEKMR+ Sbjct: 497 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQ 556 Query: 180 E 180 E Sbjct: 557 E 557 Score = 207 bits (528), Expect = 5e-54 Identities = 117/221 (52%), Positives = 156/221 (70%), Gaps = 26/221 (11%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63 EE+++E+E+K+RE+EE MR QEE M E+EEKMR QEE MWE+EEK++E EEKM EQE K+ Sbjct: 301 EEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KI 359 Query: 64 WEQEEKMWEQQRLPEQKE------KMWEQDERLREKEERMREQ----------------K 101 EQEEK E++++ EQ++ KMW Q+E++RE+EE++REQ K Sbjct: 360 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 419 Query: 102 MWQQVEKMR---EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 158 MW+Q E+M+ EK + QEEK++EQE+K++EQEE + EQEE MQEQEEKM EQE KM EQ Sbjct: 420 MWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQ 479 Query: 159 EEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199 E KM+EQEEKM+ QEEK+R+ E E E + QE Sbjct: 480 EAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 520 Score = 182 bits (461), Expect = 3e-46 Identities = 103/171 (60%), Positives = 129/171 (75%), Gaps = 12/171 (7%) Query: 16 EEEEMM----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 71 EE E+ ++QEEKM QEEK++E+EEK+ EQEEK++EQEEKM QEE MWE+EEKM Sbjct: 274 EENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMR 333 Query: 72 EQQRLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMREKKKTQE-EKMQEQEEKMQE 129 Q+ E MWE++E++RE EE+M EQ K+ +Q EK +E++K +E EK QEQE KM Sbjct: 334 RQE------EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 387 Query: 130 QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 QEE + EQEEK++EQEE M EQEEKM EQEEKM EQEE+MQ QEEKMR E Sbjct: 388 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQE 438 Score = 136 bits (342), Expect = 2e-32 Identities = 77/130 (59%), Positives = 100/130 (76%), Gaps = 16/130 (12%) Query: 1 MREEER-MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 +RE+E M+E+E+KM E+E M EQE KMQEQEEKMR QEEK+ EQE+K++EQEEK+ EQ Sbjct: 455 IREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 514 Query: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119 EE M EQEEKMWEQ+ EKM EQ+E+++E+EE+MR Q+ EKMRE QE + Sbjct: 515 EEMMQEQEEKMWEQE------EKMCEQEEKMQEQEEKMRRQE-----EKMRE----QEVR 559 Query: 120 MQEQEEKMQE 129 +++QEEKMQE Sbjct: 560 LRQQEEKMQE 569 Score = 112 bits (281), Expect = 2e-25 Identities = 66/205 (32%), Positives = 126/205 (61%), Gaps = 11/205 (5%) Query: 9 EREKKMREEEEMMREQEEKMQE------QEEKMREQEEKMWEQEEKMQEQEEKMW---EQ 59 +++K R EE+ +E++ E +E+++E+ K+ E+ + ++ ++ ++ ++ Sbjct: 175 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 234 Query: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK-EERMREQKMWQQVEKMREKKK-TQE 117 ++ E+ + + QQ+L + + + ++ + + K + ++ E ++W ++ + +E+K QE Sbjct: 235 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 294 Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 EK+QE+EEK+QEQEE + EQEEKM+ QEE MWE+EEKMR QEE M E+EEK++ EEKM Sbjct: 295 EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 354 Query: 178 DVEPAGGEAGEGSPQDNPTAQEIMQ 202 + E + + ++ QE Q Sbjct: 355 EQEKIREQEEKRQEEEKIREQEKRQ 379 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 226 bits (575), Expect = 2e-59 Identities = 121/231 (52%), Positives = 162/231 (70%), Gaps = 34/231 (14%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+EE+M E+E+K+RE+E+ M QEEK++EQEEK+REQEEKMW QEEK++EQ+EK+ EQEE Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMR--------- 110 +MW QEEK+ EQ+ +++EKMW Q++++RE++E++REQ +MW+Q EK+R Sbjct: 389 EMWRQEEKIREQEE--KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ 446 Query: 111 ---------------EKKKTQEEKMQEQEEKMQEQEEMMW------EQEEKMQEQEEKMW 149 EK + QEEK+Q QEEK+QEQEE W +QEEK+ EQEEKMW Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506 Query: 150 EQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEI 200 QEEKM EQEEKM+EQEEKMQ QEEKMR+ E + E + QE+ Sbjct: 507 RQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL 557 Score = 222 bits (566), Expect = 2e-58 Identities = 112/177 (63%), Positives = 149/177 (84%), Gaps = 5/177 (2%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 +EE+M E+E K+RE+EE M QEEKM EQEEK+REQE+KMW QEEK++EQEEK+ EQEEK Sbjct: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368 Query: 63 MWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR---EKKKTQEE 118 MW QEEK+ EQ +++ EQ+E+MW Q+E++RE+EE+ R++KMW+Q +KMR EK + QEE Sbjct: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK-RQEKMWRQEKKMREQDEKIREQEE 427 Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175 +M QEEK++E EEMM +QEEK++E EEKM E+EEKM+EQEEK++ QEEK+Q QEEK Sbjct: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484 Score = 215 bits (548), Expect = 2e-56 Identities = 108/183 (59%), Positives = 150/183 (81%), Gaps = 10/183 (5%) Query: 8 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67 +++E+KM +EE ++EQEEKM EQE K+REQEEKMW QEEKM EQEEK+ EQE+KMW QE Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352 Query: 68 EKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKT-------QE 117 EK+ EQ+ ++ EQ+EKMW Q+E++RE++E+++EQ+ MW+Q EK+RE+++ QE Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412 Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 +KM+EQ+EK++EQEE MW QEEK++E EE M +QEEK+RE EEKM+E+EEKMQ QEEK++ Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472 Query: 178 DVE 180 E Sbjct: 473 RQE 475 Score = 186 bits (471), Expect = 2e-47 Identities = 107/182 (58%), Positives = 135/182 (74%), Gaps = 27/182 (14%) Query: 16 EEEEMM----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 71 EE E+ ++QEEKM QEEK++EQEEKM EQE K++EQEEKMW QEEKM EQEEK Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK-- 340 Query: 72 EQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEEKMQEQEEKMQE 129 + EQ++KMW Q+E++RE+EE++REQ KMW+Q EK+RE Q+EK+QEQEE+M Sbjct: 341 ----IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE----QDEKIQEQEEEMWR 392 Query: 130 QEEMMWEQEEKMQE----QEEKMWEQEEKMRE-------QEEKMREQEEKMQGQEEKMRD 178 QEE + EQEEK QE QE+KM EQ+EK+RE QEEK+RE EE MQ QEEK+R+ Sbjct: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLRE 452 Query: 179 VE 180 VE Sbjct: 453 VE 454 Score = 162 bits (410), Expect = 2e-40 Identities = 95/210 (45%), Positives = 131/210 (62%), Gaps = 40/210 (19%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+EE++RE E+ M+++EE +RE EEKMQE+EEKM+EQEEK+ QEEK+QEQEEK W QE Sbjct: 431 RQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE- 489 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121 K+ +QEEK+WEQ+ EKMW Q+E++ E+EE+M+EQ+ EKM+ Sbjct: 490 KLLKQEEKIWEQE------EKMWRQEEKMWEQEEKMQEQE-----EKMQ----------- 527 Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEP 181 QEEKM+EQE +W+QEEKMQEQE ++ E EE++ + +K E Sbjct: 528 RQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK-----------------AEL 570 Query: 182 AGGEAGEGSPQDNPTAQEIMQLFCGMKNAQ 211 GG E Q PT I+Q+ + AQ Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQ 600 Score = 132 bits (332), Expect = 3e-31 Identities = 71/194 (36%), Positives = 131/194 (67%), Gaps = 22/194 (11%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK--MWEQEEKMQEQEEKMWEQEE 61 +E ++E+ +++E+ ++ ++ ++Q + ++ + E+ + ++++Q + +++ ++ + Sbjct: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ 272 Query: 62 KMWEQEEKMWEQQRL-----PEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKK-- 114 + + + E+ L +Q+EKMW Q+E+++E+EE+M EQ+ K+RE+++ Sbjct: 273 SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE-----LKIREQEEKM 327 Query: 115 -TQEEKMQEQEEKMQEQEEMMW-------EQEEKMQEQEEKMWEQEEKMREQEEKMREQE 166 QEEKM EQEEK++EQE+ MW EQEEK++EQEEKMW QEEK+REQ+EK++EQE Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387 Query: 167 EKMQGQEEKMRDVE 180 E+M QEEK+R+ E Sbjct: 388 EEMWRQEEKIREQE 401 Score = 100 bits (250), Expect = 8e-22 Identities = 59/134 (44%), Positives = 86/134 (64%), Gaps = 10/134 (7%) Query: 2 REEERMRE------REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 55 R+EE+++E R++K+ ++EE + EQEEKM QEEKM EQEEKM EQEEKMQ QEEK Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532 Query: 56 MWEQEEKMWEQEEKMWEQ----QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMRE 111 M EQE ++W+QEEKM EQ Q L E+ K+ ++ E L Q++ ++ Sbjct: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQV 592 Query: 112 KKKTQEEKMQEQEE 125 + K+QE + +Q++ Sbjct: 593 ELKSQEAQSLQQQQ 606 Score = 95.5 bits (236), Expect = 4e-20 Identities = 61/182 (33%), Positives = 102/182 (56%), Gaps = 5/182 (2%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE----KMWEQEEKMQEQEEKMWEQ 59 E ++R + EE + + +M EK+ ++ + +++ +E +EK E Sbjct: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAEL 223 Query: 60 EEKM-WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118 +EK+ + EK Q + + K K+ L +++ ++ ++ ++++ + K + Q E Sbjct: 224 QEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE 283 Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178 + + Q+QEE MW QEEK+QEQEEKM EQE K+REQEEKM QEEKM QEEK+R+ Sbjct: 284 ENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE 343 Query: 179 VE 180 E Sbjct: 344 QE 345 Score = 45.1 bits (105), Expect = 6e-05 Identities = 61/267 (22%), Positives = 103/267 (38%), Gaps = 93/267 (34%) Query: 5 ERMREREKKMREEEEMMREQEEKMQEQEEKMRE----------QEEKMWEQEEKMQEQEE 54 E + R K +E++ + E E+ Q +E R ++ + ++ E + Sbjct: 74 ENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKS 133 Query: 55 KMWEQEEKMWEQE---------EKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQ 105 +++EKM E+ +K W RL E + ++ L E +M Sbjct: 134 SFKKRQEKMNEKNYTFRKRVVIKKPW--LRLGEVTAQKRPENSLLEETLHFDHAVRMGTY 191 Query: 106 VEKMREKK--------------KTQEEKMQEQEEKMQ--------------------EQE 131 +EK+ +++ + +EK E +EK++ E+ Sbjct: 192 IEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251 Query: 132 EMMWEQEE-----------------KMQEQEE--------------KMWEQEEKMREQEE 160 +++ Q++ K+Q Q E KMW QEEK++EQEE Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311 Query: 161 KM-------REQEEKMQGQEEKMRDVE 180 KM REQEEKM QEEKM + E Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQE 338 Score = 28.1 bits (61), Expect = 7.0 Identities = 21/102 (20%), Positives = 43/102 (42%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 ++EE+M+E+E +++E EE + + +K + RE + + + E K E + Sbjct: 542 QQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW 103 +Q+ Q+ +++ E L R K W Sbjct: 602 LQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRW 643 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 226 bits (575), Expect = 2e-59 Identities = 121/231 (52%), Positives = 162/231 (70%), Gaps = 34/231 (14%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+EE+M E+E+K+RE+E+ M QEEK++EQEEK+REQEEKMW QEEK++EQ+EK+ EQEE Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMR--------- 110 +MW QEEK+ EQ+ +++EKMW Q++++RE++E++REQ +MW+Q EK+R Sbjct: 389 EMWRQEEKIREQEE--KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ 446 Query: 111 ---------------EKKKTQEEKMQEQEEKMQEQEEMMW------EQEEKMQEQEEKMW 149 EK + QEEK+Q QEEK+QEQEE W +QEEK+ EQEEKMW Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506 Query: 150 EQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEI 200 QEEKM EQEEKM+EQEEKMQ QEEKMR+ E + E + QE+ Sbjct: 507 RQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL 557 Score = 222 bits (566), Expect = 2e-58 Identities = 112/177 (63%), Positives = 149/177 (84%), Gaps = 5/177 (2%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 +EE+M E+E K+RE+EE M QEEKM EQEEK+REQE+KMW QEEK++EQEEK+ EQEEK Sbjct: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368 Query: 63 MWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR---EKKKTQEE 118 MW QEEK+ EQ +++ EQ+E+MW Q+E++RE+EE+ R++KMW+Q +KMR EK + QEE Sbjct: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK-RQEKMWRQEKKMREQDEKIREQEE 427 Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175 +M QEEK++E EEMM +QEEK++E EEKM E+EEKM+EQEEK++ QEEK+Q QEEK Sbjct: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484 Score = 215 bits (548), Expect = 2e-56 Identities = 108/183 (59%), Positives = 150/183 (81%), Gaps = 10/183 (5%) Query: 8 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67 +++E+KM +EE ++EQEEKM EQE K+REQEEKMW QEEKM EQEEK+ EQE+KMW QE Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352 Query: 68 EKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKT-------QE 117 EK+ EQ+ ++ EQ+EKMW Q+E++RE++E+++EQ+ MW+Q EK+RE+++ QE Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412 Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 +KM+EQ+EK++EQEE MW QEEK++E EE M +QEEK+RE EEKM+E+EEKMQ QEEK++ Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472 Query: 178 DVE 180 E Sbjct: 473 RQE 475 Score = 186 bits (471), Expect = 2e-47 Identities = 107/182 (58%), Positives = 135/182 (74%), Gaps = 27/182 (14%) Query: 16 EEEEMM----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 71 EE E+ ++QEEKM QEEK++EQEEKM EQE K++EQEEKMW QEEKM EQEEK Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK-- 340 Query: 72 EQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEEKMQEQEEKMQE 129 + EQ++KMW Q+E++RE+EE++REQ KMW+Q EK+RE Q+EK+QEQEE+M Sbjct: 341 ----IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE----QDEKIQEQEEEMWR 392 Query: 130 QEEMMWEQEEKMQE----QEEKMWEQEEKMRE-------QEEKMREQEEKMQGQEEKMRD 178 QEE + EQEEK QE QE+KM EQ+EK+RE QEEK+RE EE MQ QEEK+R+ Sbjct: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLRE 452 Query: 179 VE 180 VE Sbjct: 453 VE 454 Score = 162 bits (410), Expect = 2e-40 Identities = 95/210 (45%), Positives = 131/210 (62%), Gaps = 40/210 (19%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+EE++RE E+ M+++EE +RE EEKMQE+EEKM+EQEEK+ QEEK+QEQEEK W QE Sbjct: 431 RQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE- 489 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121 K+ +QEEK+WEQ+ EKMW Q+E++ E+EE+M+EQ+ EKM+ Sbjct: 490 KLLKQEEKIWEQE------EKMWRQEEKMWEQEEKMQEQE-----EKMQ----------- 527 Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEP 181 QEEKM+EQE +W+QEEKMQEQE ++ E EE++ + +K E Sbjct: 528 RQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK-----------------AEL 570 Query: 182 AGGEAGEGSPQDNPTAQEIMQLFCGMKNAQ 211 GG E Q PT I+Q+ + AQ Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQ 600 Score = 132 bits (332), Expect = 3e-31 Identities = 71/194 (36%), Positives = 131/194 (67%), Gaps = 22/194 (11%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK--MWEQEEKMQEQEEKMWEQEE 61 +E ++E+ +++E+ ++ ++ ++Q + ++ + E+ + ++++Q + +++ ++ + Sbjct: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ 272 Query: 62 KMWEQEEKMWEQQRL-----PEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKK-- 114 + + + E+ L +Q+EKMW Q+E+++E+EE+M EQ+ K+RE+++ Sbjct: 273 SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE-----LKIREQEEKM 327 Query: 115 -TQEEKMQEQEEKMQEQEEMMW-------EQEEKMQEQEEKMWEQEEKMREQEEKMREQE 166 QEEKM EQEEK++EQE+ MW EQEEK++EQEEKMW QEEK+REQ+EK++EQE Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387 Query: 167 EKMQGQEEKMRDVE 180 E+M QEEK+R+ E Sbjct: 388 EEMWRQEEKIREQE 401 Score = 100 bits (250), Expect = 8e-22 Identities = 59/134 (44%), Positives = 86/134 (64%), Gaps = 10/134 (7%) Query: 2 REEERMRE------REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 55 R+EE+++E R++K+ ++EE + EQEEKM QEEKM EQEEKM EQEEKMQ QEEK Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532 Query: 56 MWEQEEKMWEQEEKMWEQ----QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMRE 111 M EQE ++W+QEEKM EQ Q L E+ K+ ++ E L Q++ ++ Sbjct: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQV 592 Query: 112 KKKTQEEKMQEQEE 125 + K+QE + +Q++ Sbjct: 593 ELKSQEAQSLQQQQ 606 Score = 95.5 bits (236), Expect = 4e-20 Identities = 61/182 (33%), Positives = 102/182 (56%), Gaps = 5/182 (2%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE----KMWEQEEKMQEQEEKMWEQ 59 E ++R + EE + + +M EK+ ++ + +++ +E +EK E Sbjct: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAEL 223 Query: 60 EEKM-WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118 +EK+ + EK Q + + K K+ L +++ ++ ++ ++++ + K + Q E Sbjct: 224 QEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE 283 Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178 + + Q+QEE MW QEEK+QEQEEKM EQE K+REQEEKM QEEKM QEEK+R+ Sbjct: 284 ENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE 343 Query: 179 VE 180 E Sbjct: 344 QE 345 Score = 45.1 bits (105), Expect = 6e-05 Identities = 61/267 (22%), Positives = 103/267 (38%), Gaps = 93/267 (34%) Query: 5 ERMREREKKMREEEEMMREQEEKMQEQEEKMRE----------QEEKMWEQEEKMQEQEE 54 E + R K +E++ + E E+ Q +E R ++ + ++ E + Sbjct: 74 ENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKS 133 Query: 55 KMWEQEEKMWEQE---------EKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQ 105 +++EKM E+ +K W RL E + ++ L E +M Sbjct: 134 SFKKRQEKMNEKNYTFRKRVVIKKPW--LRLGEVTAQKRPENSLLEETLHFDHAVRMGTY 191 Query: 106 VEKMREKK--------------KTQEEKMQEQEEKMQ--------------------EQE 131 +EK+ +++ + +EK E +EK++ E+ Sbjct: 192 IEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251 Query: 132 EMMWEQEE-----------------KMQEQEE--------------KMWEQEEKMREQEE 160 +++ Q++ K+Q Q E KMW QEEK++EQEE Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311 Query: 161 KM-------REQEEKMQGQEEKMRDVE 180 KM REQEEKM QEEKM + E Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQE 338 Score = 28.1 bits (61), Expect = 7.0 Identities = 21/102 (20%), Positives = 43/102 (42%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 ++EE+M+E+E +++E EE + + +K + RE + + + E K E + Sbjct: 542 QQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW 103 +Q+ Q+ +++ E L R K W Sbjct: 602 LQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRW 643 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 222 bits (566), Expect = 2e-58 Identities = 115/182 (63%), Positives = 153/182 (84%), Gaps = 6/182 (3%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 +E++M +E+K+RE+EE + QEEK++EQEEK +EQEEKMW+QEEK++EQEEK+ EQEEK Sbjct: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627 Query: 63 MWEQEEKMWEQQRLP-EQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKT---Q 116 + EQEEK+ EQ+ + EQ+EKM EQ+E++ E+EE+M+EQ+ MW+Q EK+RE++K Q Sbjct: 628 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQ 687 Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 EEK++EQEE MQEQEE MWEQEEKM EQEEKM EQEEKMR QEEKM EQE +++ QEEKM Sbjct: 688 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 747 Query: 177 RD 178 ++ Sbjct: 748 QE 749 Score = 220 bits (561), Expect = 7e-58 Identities = 118/231 (51%), Positives = 160/231 (69%), Gaps = 35/231 (15%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R++E+M E+E+K+R++EE + QEEK++EQEEK+REQEEKMW QEEK++EQEE MW +EE Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE-MWREEE 551 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERM----------------REQKMWQQ 105 KM EQE K+WE+++ EQ++KMW Q+E++RE+EE++ +E+KMW+Q Sbjct: 552 KMHEQE-KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610 Query: 106 VEKMREKK-----------------KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKM 148 EK+RE++ + QEE QEQEEKM EQEE M EQEEKMQEQEE M Sbjct: 611 EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM 670 Query: 149 WEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199 W QEEK+REQE+K+REQEEK++ QEE M++ E E E + QE Sbjct: 671 WRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 721 Score = 219 bits (559), Expect = 1e-57 Identities = 119/192 (61%), Positives = 153/192 (79%), Gaps = 15/192 (7%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 REEE+M E+EK EEE +EQE+KM QEEK+REQEEK+W QEEK++EQEEK EQEE Sbjct: 548 REEEKMHEQEKIW--EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605 Query: 62 KMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ---------KMWQQVEKMRE 111 KMW+QEEK+ EQ+ ++ EQ+EK+ EQ+E++RE+EE +EQ KM +Q EKM+E Sbjct: 606 KMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 665 Query: 112 KKKT---QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168 +++T QEEK++EQE+K++EQEE + EQEE MQEQEEKMWEQEEKM EQEEKM+EQEEK Sbjct: 666 QEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725 Query: 169 MQGQEEKMRDVE 180 M+ QEEKM + E Sbjct: 726 MRRQEEKMWEQE 737 Score = 217 bits (552), Expect = 8e-57 Identities = 112/198 (56%), Positives = 152/198 (76%), Gaps = 4/198 (2%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 +E+E M +E+K+ E+EE+ R Q+EKM EQEEK+R+QEEK+W QEEK++EQEEK+ EQEE Sbjct: 473 QEQEEMWRQEEKIHEQEEIWR-QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEE 531 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT---QEE 118 KMW QEEK+ EQ+ + ++EKM EQ++ E++ + +E KMW+Q EK+RE+++ QEE Sbjct: 532 KMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE 591 Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178 K++EQEEK QEQEE MW+QEEK++EQEEK+ EQEEK+REQEEK+REQEE Q QEEKM + Sbjct: 592 KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE 651 Query: 179 VEPAGGEAGEGSPQDNPT 196 E E E + T Sbjct: 652 QEEKMCEQEEKMQEQEET 669 Score = 215 bits (548), Expect = 2e-56 Identities = 115/206 (55%), Positives = 156/206 (75%), Gaps = 28/206 (13%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE-------- 53 +EEE++RE+EK+ +E +M R QEEK++EQEEK+REQE+KMW QEEK+ EQE Sbjct: 414 QEEEKIREQEKRQEQEAKMWR-QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 472 Query: 54 ---EKMWEQEEKM------WEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ--K 101 E+MW QEEK+ W Q+EKM EQ+ ++ +Q+EK+W Q+E++RE+EE++REQ K Sbjct: 473 QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEK 532 Query: 102 MWQQVEKMREKKKT--QEEKMQEQE-----EKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 154 MW+Q EK+RE+++ +EEKM EQE EK QEQE+ MW QEEK++EQEEK+W QEEK Sbjct: 533 MWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK 592 Query: 155 MREQEEKMREQEEKMQGQEEKMRDVE 180 +REQEEK +EQEEKM QEEK+R+ E Sbjct: 593 IREQEEKRQEQEEKMWKQEEKIREQE 618 Score = 213 bits (543), Expect = 9e-56 Identities = 121/241 (50%), Positives = 163/241 (67%), Gaps = 41/241 (17%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQ-------EQEEKMREQEEKMWEQEEKMQEQEEK 55 +EE++RE+E+KMR +EEMM E+EEKM+ E+EEKMR QEE MWE+EEKM+ QEE Sbjct: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 385 Query: 56 MWEQEEKMWEQEEKMWEQQRLPEQKE-------------------KMWEQDERLREKEER 96 MWE+EEK+ E EEKM EQ+++ EQ+E KMW Q+E++RE+EE+ Sbjct: 386 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 445 Query: 97 MREQ--KMWQQVEKMREKKKTQE-------EKMQEQEEKMQEQEEM------MWEQEEKM 141 +REQ KMW+Q EK+ E++K +E E+M QEEK+ EQEE+ M EQEEK+ Sbjct: 446 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505 Query: 142 QEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEIM 201 ++QEEK+W QEEK+REQEEK+REQEEKM QEEK+R+ E E + Q+ +E Sbjct: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKR 565 Query: 202 Q 202 Q Sbjct: 566 Q 566 Score = 207 bits (528), Expect = 5e-54 Identities = 110/220 (50%), Positives = 153/220 (69%), Gaps = 41/220 (18%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+EE+++E E+K++E+EE +REQEEK++EQEEKMR QEE MWE+EEKM+ QEE MWE+EE Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363 Query: 62 KMWEQEEKMWE-QQRLPEQKEKMWEQDERLREKEERMREQKMW-------QQVEKMREKK 113 KM QEE MWE ++++ Q+E MWE++E++RE EE+M EQ+ Q+ EK+RE++ Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423 Query: 114 KTQE---------EKMQEQEEKMQEQEEMMWEQEEKMQEQE------------------- 145 K QE EK++EQEEK++EQE+ MW QEEK+ EQE Sbjct: 424 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 483 Query: 146 -----EKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 E++W Q+EKM EQEEK+R+QEEK+ QEEK+R+ E Sbjct: 484 KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQE 523 Score = 198 bits (503), Expect = 4e-51 Identities = 112/212 (52%), Positives = 152/212 (71%), Gaps = 16/212 (7%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE-----EKM 56 R+EE M E+E+KMR +EEMM E+EEK++E EEKM EQE K+ EQEEK QE+E EK Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KIREQEEKRQEEEKIREQEKR 425 Query: 57 WEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQD------ERLREKEERMREQKMWQQVEKM 109 EQE KMW QEEK+ EQ+ ++ EQ++KMW Q+ E++RE+E+R +++MW+Q EK+ Sbjct: 426 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 485 Query: 110 REKKK--TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167 E+++ Q+EKM EQEEK+++QEE +W QEEK++EQEEK+ EQEEKM QEEK+REQEE Sbjct: 486 HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE 545 Query: 168 KMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199 M +EEKM + E E +D QE Sbjct: 546 -MWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576 Score = 187 bits (476), Expect = 5e-48 Identities = 100/169 (59%), Positives = 137/169 (81%), Gaps = 13/169 (7%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+EE++RE+E+K +E+EE M +QEEK++EQEEK++EQEEK+ EQEEK++EQEE EQEE Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE 647 Query: 62 KMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKT--- 115 KM EQEEKM EQ+ ++ EQ+E MW Q+E++RE+E+++REQ K+ +Q E M+E+++ Sbjct: 648 KMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707 Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164 QEEKM EQEEKMQ EQEEKM+ QEEKMWEQE ++R+QEEKM+E Sbjct: 708 QEEKMCEQEEKMQ-------EQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749 Score = 158 bits (399), Expect = 4e-39 Identities = 90/187 (48%), Positives = 130/187 (69%), Gaps = 20/187 (10%) Query: 1 MREEERMREREKKMREEEEMMREQE---EKMQEQEEKMREQ--EEKMWEQEEKMQEQEEK 55 ++E +R ER K + ++++ E + +++Q K++ Q E ++W + Q+QEEK Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN--QQQEEK 301 Query: 56 MWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMR--EQKMWQQVEKMREKK 113 MW QEEK+ E EEK + EQ+EK+ EQ+E++RE+EE+MR E+ MW++ EKMR Sbjct: 302 MWRQEEKIQEWEEK------IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR-- 353 Query: 114 KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 173 QEE M E+EEKM+ QEEMMWE+EEKM+ QEE MWE+EEK+RE EEKM EQ EK++ QE Sbjct: 354 --QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ-EKIREQE 410 Query: 174 EKMRDVE 180 EK ++ E Sbjct: 411 EKRQEEE 417 Score = 135 bits (340), Expect = 3e-32 Identities = 75/125 (60%), Positives = 98/125 (78%), Gaps = 13/125 (10%) Query: 1 MREEERM-REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 +RE+E M +E+E+KM E+EE M EQEEKMQEQEE M QEEK+ EQE+K++EQEEK+ EQ Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694 Query: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMR--EQKMWQQVEKMREKKKTQE 117 EE M EQEEKMWEQ+ EKM EQ+E+++E+EE+MR E+KMW+Q ++R+ QE Sbjct: 695 EEMMQEQEEKMWEQE------EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ----QE 744 Query: 118 EKMQE 122 EKMQE Sbjct: 745 EKMQE 749 Score = 85.9 bits (211), Expect = 3e-17 Identities = 65/195 (33%), Positives = 90/195 (46%), Gaps = 74/195 (37%) Query: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK-------------------------- 93 EE E++ E R E++ E++ +L+EK Sbjct: 196 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 255 Query: 94 --------------------------EERMREQKMW-----QQVEKM-REKKKTQE---- 117 + ++ E ++W QQ EKM R+++K QE Sbjct: 256 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK 315 Query: 118 ------------EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 165 EK++EQEEKM+ QEEMMWE+EEKM+ QEE MWE+EEKMR QEE M E+ Sbjct: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 375 Query: 166 EEKMQGQEEKMRDVE 180 EEKM+ QEE M + E Sbjct: 376 EEKMRRQEEMMWEKE 390 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 218 bits (554), Expect = 5e-57 Identities = 115/185 (62%), Positives = 153/185 (82%), Gaps = 7/185 (3%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 +E+E M +E+K+RE+EE+ R Q+EK+ EQEEK+R+QEEKMW QEEKM +QEEK+ EQEE Sbjct: 520 QEQEEMWRQEEKIREQEEIWR-QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEE 578 Query: 62 KMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERM--REQKMWQQVEKMR---EKKKT 115 K+W QEEK+ EQ +++ EQ+EK+ EQ+E +E+EE+M +E+KM +Q EKM+ EK + Sbjct: 579 KVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRR 638 Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175 QEEK++EQE+K++EQEE + EQEE MQEQEEKMWEQEEKM EQEEKM+EQEEKM+ QEEK Sbjct: 639 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 698 Query: 176 MRDVE 180 M + E Sbjct: 699 MWEQE 703 Score = 216 bits (549), Expect = 2e-56 Identities = 118/231 (51%), Positives = 159/231 (68%), Gaps = 34/231 (14%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 +EE++RE+E+K+RE+EE MR QEE M E+EEKMR QEE MWE+EEKM+ QEE MWE+EEK Sbjct: 380 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 439 Query: 63 MWEQEEKMWEQQRLPEQKEK-------------------MWEQDERLREKEERMREQ--K 101 + E EEKM EQ+++ EQ+EK MW Q+E++RE+EE++REQ K Sbjct: 440 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499 Query: 102 MWQQVEKMREKKKTQEEK-------MQEQEEKMQEQEEM------MWEQEEKMQEQEEKM 148 MW+Q EK+ E++K +EE+ M QEEK++EQEE+ + EQEEK+++QEEKM Sbjct: 500 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKM 559 Query: 149 WEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199 W QEEKM +QEEK+REQEEK+ QEEK+R+ E E E + QE Sbjct: 560 WRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQE 610 Score = 216 bits (549), Expect = 2e-56 Identities = 108/178 (60%), Positives = 148/178 (83%), Gaps = 3/178 (1%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R++E++ E+E+K+R++EE M QEEKM +QEEK+REQEEK+W QEEK++EQEEK+ EQEE Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599 Query: 62 KMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 K+ EQEE EQ +++ EQ+EKM EQ+E+++E+EE+MR Q+ +++ + +K + QEEK+ Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQE--EKIREQEKKIREQEEKI 657 Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178 +EQEE MQEQEE MWEQEEKM EQEEKM EQEEKMR QEEKM EQE +++ QEEKM++ Sbjct: 658 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715 Score = 214 bits (545), Expect = 5e-56 Identities = 119/231 (51%), Positives = 162/231 (70%), Gaps = 25/231 (10%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE-------- 53 +EEE++RE+EK+ +E +M R QEEK++EQEEK+REQEEKMW QEEK+ EQE Sbjct: 461 QEEEKIREQEKRQEQEAKMWR-QEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKR 519 Query: 54 ---EKMWEQEEK------MWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQ--K 101 E+MW QEEK +W Q+EK+ EQ +++ +Q+EKMW Q+E++ ++EE++REQ K Sbjct: 520 QEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEK 579 Query: 102 MWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK 161 +W+Q EK+RE QEEK++EQEEK++EQEEM EQEEKM EQEEKM EQEEKM+EQEEK Sbjct: 580 VWRQEEKIRE----QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEK 635 Query: 162 MREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQ 212 MR QEEK++ QE+K+R+ E E E + E + C + Q Sbjct: 636 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 686 Score = 208 bits (529), Expect = 4e-54 Identities = 115/207 (55%), Positives = 150/207 (72%), Gaps = 29/207 (14%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+EE+++E E+K++E+EE +REQEEK++EQEEKMR QEE MWE+EEKM+ QEE MWE+EE Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424 Query: 62 KMWEQEEKMWE-QQRLPEQKEKMWEQD-----ERLREKEERMREQ--------KMWQQVE 107 KM QEE MWE ++++ E +EKM EQ+ E R++EE++REQ KMW+Q E Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484 Query: 108 KMR---EKKKTQEEKMQEQEEKMQEQE-----------EMMWEQEEKMQEQEEKMWEQEE 153 K+R EK + QEEKM QEEK+ EQE E MW QEEK++EQEE +W Q+E Sbjct: 485 KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE-IWRQKE 543 Query: 154 KMREQEEKMREQEEKMQGQEEKMRDVE 180 K+ EQEEK+R+QEEKM QEEKM D E Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQE 570 Score = 197 bits (501), Expect = 7e-51 Identities = 103/180 (57%), Positives = 142/180 (78%), Gaps = 7/180 (3%) Query: 8 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67 +++E+KM +EE ++E EEK+QEQEEK+REQEEK+ EQEEKM+ QEE MWE+EEKM QE Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 416 Query: 68 EKMWE-QQRLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMREKKKTQE-EKMQEQE 124 E MWE ++++ Q+E MWE++E++RE EE+M EQ K+ +Q EK +E++K +E EK QEQE Sbjct: 417 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 476 Query: 125 EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ----EEKMREQEEKMQGQEEKMRDVE 180 KM QEE + EQEEK++EQEEKMW QEEK+ EQ EE+ R+++E+M QEEK+R+ E Sbjct: 477 AKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 536 Score = 190 bits (483), Expect = 8e-49 Identities = 99/170 (58%), Positives = 136/170 (80%), Gaps = 10/170 (5%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+EE+M ++E+K+RE+EE + QEEK++EQEEK+REQEEK+ EQEE QEQEEKM EQEE Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620 Query: 62 KMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 KM EQEEKM EQ+ ++ Q+EK+ EQ++++RE+EE++REQ+ + +++ EK QEEKM Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE--EMMQEQEEKMWEQEEKM 678 Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 170 EQEEKMQ EQEEKM+ QEEKMWEQE ++R+QEEKM+E +E ++ Sbjct: 679 CEQEEKMQ-------EQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721 Score = 147 bits (371), Expect = 8e-36 Identities = 95/200 (47%), Positives = 134/200 (67%), Gaps = 27/200 (13%) Query: 1 MREEERMREREKKMREEEEMMREQEE----------KMQEQEEKM-------REQEEKMW 43 ++E +R ER K + ++++ E + K+Q Q E+ ++QEEKMW Sbjct: 305 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 364 Query: 44 EQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERM--REQ 100 QEEK+QE EEK+ EQEEK+ EQEEK+ EQ+ ++ Q+E MWE++E++R +EE M +E+ Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424 Query: 101 KMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160 KM +Q E M EK EEK++E EEKM EQE++ EQEEK QE EEK+ EQE K +EQE Sbjct: 425 KMRRQEEMMWEK----EEKIRELEEKMHEQEKIR-EQEEKRQE-EEKIREQE-KRQEQEA 477 Query: 161 KMREQEEKMQGQEEKMRDVE 180 KM QEEK++ QEEK+R+ E Sbjct: 478 KMWRQEEKIREQEEKIREQE 497 Score = 144 bits (364), Expect = 5e-35 Identities = 78/131 (59%), Positives = 104/131 (79%), Gaps = 13/131 (9%) Query: 1 MREEERM-REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 +RE+E M +E+E+KM E+EE M EQEEKMQEQEEKMR QEEK+ EQE+K++EQEEK+ EQ Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 660 Query: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMR--EQKMWQQVEKMREKKKTQE 117 EE M EQEEKMWEQ+ EKM EQ+E+++E+EE+MR E+KMW+Q ++R+ QE Sbjct: 661 EEMMQEQEEKMWEQE------EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ----QE 710 Query: 118 EKMQEQEEKMQ 128 EKMQE +E ++ Sbjct: 711 EKMQEHQEHLE 721 Score = 85.5 bits (210), Expect = 4e-17 Identities = 64/181 (35%), Positives = 89/181 (49%), Gaps = 60/181 (33%) Query: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK-------------------------- 93 EE E++ E R E++ E++ +L+EK Sbjct: 257 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 316 Query: 94 --------------------------EERMREQKMW-----QQVEKM-REKKKTQ--EEK 119 + ++ E ++W QQ EKM R+++K Q EEK Sbjct: 317 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK 376 Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDV 179 +QEQEEK++EQEE + EQEEKM+ QEE MWE+EEKMR QEE M E+EEKM+ QEE M + Sbjct: 377 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 436 Query: 180 E 180 E Sbjct: 437 E 437 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 216 bits (549), Expect = 2e-56 Identities = 112/177 (63%), Positives = 145/177 (81%), Gaps = 6/177 (3%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 ++EE++ +E+KM ++EE +REQEEKM QEEK+REQEEK+ EQEEK++EQEE M EQEE Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEE 551 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEEK 119 KM EQEEKM EQ+++ Q+EK+ EQ+E++RE++E++REQ K+W+Q EK+RE QEE Sbjct: 552 KMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE----QEEM 607 Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 MQEQEEKM EQEE M EQEEKMQEQEEKM QEEKM EQE ++R+QEEKMQ +E + Sbjct: 608 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664 Score = 214 bits (545), Expect = 5e-56 Identities = 109/178 (61%), Positives = 145/178 (81%), Gaps = 2/178 (1%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 M E+E++R++E+K+ +EE M +QEEK++EQEEKM QEEK+ EQEEK++EQEEK+ EQE Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 E M EQEEKM EQ+ +++EKM Q+E++RE+EE++REQK +++ + EK QEEK+ Sbjct: 544 EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK--EKIREQEEKIWEQEEKI 601 Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178 +EQEE MQEQEE MWEQEEKM EQEEKM EQEEKMR QEEKM EQE +++ QEEKM++ Sbjct: 602 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659 Score = 213 bits (543), Expect = 9e-56 Identities = 115/207 (55%), Positives = 157/207 (75%), Gaps = 29/207 (14%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE-------- 53 +EEE++RE+EK+ +E +M R QEEK++EQEEK+REQE+KMW QEEK+ EQE Sbjct: 400 QEEEKIREQEKRQEQEAKMWR-QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 458 Query: 54 ---EKMWEQEEKM------WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KM 102 E+MW QEEK+ W Q+EKM EQ+++ +Q+EK+W Q+E++ ++EE++REQ KM Sbjct: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518 Query: 103 WQQVEKMREKK---KTQEEKMQEQEEKMQEQEEMMWEQEEKMQE------QEEKMWEQEE 153 W+Q EK+RE++ + QEEK++EQEE MQEQEE M EQEEKMQE QEEK+ EQEE Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE 578 Query: 154 KMREQEEKMREQEEKMQGQEEKMRDVE 180 K+REQ+EK+REQEEK+ QEEK+R+ E Sbjct: 579 KIREQKEKIREQEEKIWEQEEKIREQE 605 Score = 212 bits (540), Expect = 2e-55 Identities = 117/191 (61%), Positives = 153/191 (80%), Gaps = 14/191 (7%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 +E+E M +E+K+RE+EE+ R Q+EKM EQE K+R+QEEK+W QEEKM +QEEK+ EQEE Sbjct: 459 QEQEEMWRQEEKIREQEEIWR-QKEKMHEQE-KIRKQEEKVWRQEEKMHDQEEKIREQEE 516 Query: 62 KMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK-MWQQVEKMR---EKKKTQ 116 KMW QEEK+ EQ+ ++ EQ+EK+ EQ+E ++E+EE+M EQ+ Q+ EKMR EK + Q Sbjct: 517 KMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576 Query: 117 EEKMQEQEEKMQEQEEMMWEQEEK-------MQEQEEKMWEQEEKMREQEEKMREQEEKM 169 EEK++EQ+EK++EQEE +WEQEEK MQEQEEKMWEQEEKM EQEEKM+EQEEKM Sbjct: 577 EEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 636 Query: 170 QGQEEKMRDVE 180 + QEEKM + E Sbjct: 637 RRQEEKMWEQE 647 Score = 212 bits (539), Expect = 3e-55 Identities = 118/231 (51%), Positives = 156/231 (67%), Gaps = 35/231 (15%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 +EE++RE+E+K+RE+EE MR QEE M E+EEKMR QEE MWE+EEKM+ EE MWE+EEK Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378 Query: 63 MWEQEEKMWEQQRLPEQKEK-------------------MWEQDERLREKEERMREQ--K 101 + E EEKM EQ+++ EQ+EK MW Q+E++RE+EE++REQ K Sbjct: 379 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 438 Query: 102 MWQQVEKMREKKKTQEEK-------MQEQEEKMQEQEEMMWEQEEKMQE------QEEKM 148 MW+Q EK+ E++K +EE+ M QEEK++EQEE+ W Q+EKM E QEEK+ Sbjct: 439 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI-WRQKEKMHEQEKIRKQEEKV 497 Query: 149 WEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199 W QEEKM +QEEK+REQEEKM QEEK+R+ E E E + QE Sbjct: 498 WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQE 548 Score = 211 bits (537), Expect = 4e-55 Identities = 119/230 (51%), Positives = 161/230 (70%), Gaps = 36/230 (15%) Query: 1 MREEERMREREKKMREEEEM------------MREQEEKMQEQEEKMREQEEKMWEQEEK 48 M E+E++RE+E+K +EEE++ M QEEK++EQEEK+REQE+KMW QEEK Sbjct: 386 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 445 Query: 49 MQEQE-----------EKMWEQEEK------MWEQEEKMWEQQRLPEQKEKMWEQDERLR 91 + EQE E+MW QEEK +W Q+EKM EQ+++ +Q+EK+W Q+E++ Sbjct: 446 IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMH 505 Query: 92 EKEERMREQ--KMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMW 149 ++EE++REQ KMW+Q EK+RE QEEK++EQEEK++EQEEMM EQEEKM EQEEKM Sbjct: 506 DQEEKIREQEEKMWRQEEKIRE----QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQ 561 Query: 150 EQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199 EQ EKMR QEEK+REQEEK++ Q+EK+R+ E E E + QE Sbjct: 562 EQ-EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQE 610 Score = 209 bits (532), Expect = 2e-54 Identities = 110/191 (57%), Positives = 149/191 (78%), Gaps = 14/191 (7%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQE-----EKMREQEEKMWEQEEKMQEQEEKMW 57 +EE++RE E+KM E+E++ REQEEK QE+E EK +EQE KMW QEEK++EQEEK+ Sbjct: 375 KEEKIRELEEKMHEQEKI-REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433 Query: 58 EQEEKMWEQEEKMWEQQRLPE-----QKEKMWEQDERLREKEERMREQKMWQQVEKMR-- 110 EQE+KMW QEEK+ EQ+++ E ++E+MW Q+E++RE+EE R+++ + EK+R Sbjct: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493 Query: 111 -EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 169 EK QEEKM +QEEK++EQEE MW QEEK++EQEEK+ EQEEK+REQEE M+EQEEKM Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553 Query: 170 QGQEEKMRDVE 180 QEEKM++ E Sbjct: 554 GEQEEKMQEQE 564 Score = 200 bits (509), Expect = 8e-52 Identities = 121/262 (46%), Positives = 164/262 (62%), Gaps = 75/262 (28%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK-------MWEQEEKMQEQEE 54 ++EE+M +E+K++E EE ++EQEEK++EQEEK+REQEEK MWE+EEKM+ QEE Sbjct: 297 QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 356 Query: 55 KMWEQEEK-------MWEQ-------EEKMWEQQRLPEQKE------------------- 81 MWE+EEK MWE+ EEKM EQ+++ EQ+E Sbjct: 357 MMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 416 Query: 82 KMWEQDERLREKEERMREQ--KMWQQVEKMREKKK--------------TQEEKMQEQE- 124 KMW Q+E++RE+EE++REQ KMW+Q EK+ E++K QEEK++EQE Sbjct: 417 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 476 Query: 125 -----------EKMQEQEEMMWEQEEKM-------QEQEEKMWEQEEKMREQEEKMREQE 166 EK+++QEE +W QEEKM +EQEEKMW QEEK+REQEEK+REQE Sbjct: 477 IWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE 536 Query: 167 EKMQGQEEKMRDVEPAGGEAGE 188 EK++ QEE M++ E GE E Sbjct: 537 EKIREQEEMMQEQEEKMGEQEE 558 Score = 193 bits (491), Expect = 1e-49 Identities = 104/199 (52%), Positives = 147/199 (73%), Gaps = 7/199 (3%) Query: 8 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67 +++E+KM +EE ++E EEK+QEQEEK+REQEEK+ EQEEKM+ QEE MWE+EEKM QE Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355 Query: 68 EKMWE-QQRLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMREKKKTQE-EKMQEQE 124 E MWE ++++ +E MWE++E++RE EE+M EQ K+ +Q EK +E++K +E EK QEQE Sbjct: 356 EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 415 Query: 125 EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ----EEKMREQEEKMQGQEEKMRDVE 180 KM QEE + EQEEK++EQE+KMW QEEK+ EQ EE+ R+++E+M QEEK+R+ E Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 475 Query: 181 PAGGEAGEGSPQDNPTAQE 199 + + Q+ QE Sbjct: 476 EIWRQKEKMHEQEKIRKQE 494 Score = 145 bits (365), Expect = 4e-35 Identities = 92/201 (45%), Positives = 133/201 (66%), Gaps = 29/201 (14%) Query: 1 MREEERMREREKKMREEEEMMREQEE----------KMQEQEEKM-------REQEEKMW 43 ++E +R ER K + ++++ E + K+Q Q E+ ++QEEKMW Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 303 Query: 44 EQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKM 102 QEEK+QE EEK+ EQEEK+ EQEEK+ EQ+ ++ Q+E MWE++E++R +EE M Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM----- 358 Query: 103 WQQVEKMREKKKT---QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 159 W++ EKMR ++ +EEK++E EEKM EQE++ EQEEK QE EEK+ EQE K +EQE Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIR-EQEEKRQE-EEKIREQE-KRQEQE 415 Query: 160 EKMREQEEKMQGQEEKMRDVE 180 KM QEEK++ QEEK+R+ E Sbjct: 416 AKMWRQEEKIREQEEKIREQE 436 Score = 85.9 bits (211), Expect = 3e-17 Identities = 42/64 (65%), Positives = 54/64 (84%), Gaps = 1/64 (1%) Query: 1 MREEER-MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 +RE+E M+E+E+KM E+EE M EQEEKMQEQEEKMR QEEKMWEQE ++++QEEKM E Sbjct: 601 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 660 Query: 60 EEKM 63 +E + Sbjct: 661 QEHL 664 Score = 83.6 bits (205), Expect = 1e-16 Identities = 59/174 (33%), Positives = 85/174 (48%), Gaps = 53/174 (30%) Query: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK-------------------------- 93 EE E++ E R E++ E++ +L+EK Sbjct: 196 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 255 Query: 94 --------------------------EERMREQKMWQQVEKMREKKK-TQEEKMQEQEEK 126 + ++ E ++W ++ + +E+K QEEK+QE EEK Sbjct: 256 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK 315 Query: 127 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 +QEQEE + EQEEK++EQEEKM QEE M E+EEKMR QEE M +EEKMR +E Sbjct: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLE 369 Score = 51.2 bits (121), Expect = 8e-07 Identities = 27/49 (55%), Positives = 39/49 (79%), Gaps = 2/49 (4%) Query: 3 EEERMREREKKMREEEEMM-REQEEKMQEQEEKMREQEEKMWEQEEKMQ 50 +EE+M E+E+KM+E+EE R QEEKM EQE ++R+QEEKM E +E ++ Sbjct: 618 QEEKMCEQEEKMQEQEEK-MRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 202 bits (513), Expect = 3e-52 Identities = 107/204 (52%), Positives = 163/204 (79%), Gaps = 7/204 (3%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 +EE+M+++E++M E+EE MR+QEE+M EQEE++++QEE++ +QEE+M++QEE+M EQEE+ Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQ 270 Query: 63 MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKK---TQE 117 M EQEE+M +Q+ EQ+E+ EQ+E++RE+EE+MREQ +M +Q E+MRE+++ QE Sbjct: 271 MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQE 330 Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 E+M EQ+E+M EQ+E MW+QEE+M EQEE+M +QEE++R+QEE+MR+QEE+M+ QEE+MR Sbjct: 331 EQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMR 390 Query: 178 DVEPAGGEAGE--GSPQDNPTAQE 199 E GE E G ++ QE Sbjct: 391 KQEEQMGEQKEQMGEQKEQMREQE 414 Score = 197 bits (502), Expect = 5e-51 Identities = 103/187 (55%), Positives = 151/187 (80%), Gaps = 16/187 (8%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQ-------------EQEEKMREQEEKMWEQEEK 48 ++EE+MR++E++MRE+EE MREQEE+M EQEE+MREQEE+M EQEE+ Sbjct: 252 KQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQ 311 Query: 49 MQEQEEKMWEQEEKMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVE 107 M+EQEE+M EQEE+M +QEE+MWEQ +++ EQKE+MW+Q+E++ E+EE+M++Q+ +QV Sbjct: 312 MREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQE--EQVR 369 Query: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167 K E+ + QEE+M++QEE+M++QEE M EQ+E+M EQ+E+M EQEE+M EQ+E+MR+QEE Sbjct: 370 KQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429 Query: 168 KMQGQEE 174 M Q+E Sbjct: 430 HMGEQKE 436 Score = 194 bits (493), Expect = 6e-50 Identities = 105/198 (53%), Positives = 161/198 (81%), Gaps = 12/198 (6%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW----- 57 +EE+MR++E++M E+EE +++QEE++Q+QEE+MR+QEE+M EQEE+M+EQEE+M Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQ 284 Query: 58 -EQEEKMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERM--REQKMWQQVEKMREKK 113 EQEE+ EQEE+M EQ +++ EQ+E+M EQ+E++RE+EE+M +E++MW+Q E+M E+K Sbjct: 285 TEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQK 344 Query: 114 K---TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 170 + QEE+M EQEE+MQ+QEE + +QEE+M++QEE+M +QEE+MR+QEE+M EQ+E+M Sbjct: 345 EQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMG 404 Query: 171 GQEEKMRDVEPAGGEAGE 188 Q+E+MR+ E GE E Sbjct: 405 EQKEQMREQEEQMGEQKE 422 Score = 186 bits (472), Expect = 2e-47 Identities = 104/214 (48%), Positives = 157/214 (73%), Gaps = 34/214 (15%) Query: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 +RE+E ++RE+E ++RE+E +REQE +M EQE +M EQEE+M EQEE+MQ+QEE+M EQ Sbjct: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225 Query: 60 EEKMWEQEEKMWEQ--------QRLPEQKEKMWEQDERLREKEERMREQ----------- 100 EE+M +QEE+M EQ +++ +Q+E+M +Q+E++RE+EE+MREQ Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285 Query: 101 -----------KMWQQVEKMREKK---KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEE 146 +M +Q E+MRE++ + QEE+M+EQEE+M +QEE MWEQ+E+M EQ+E Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE 345 Query: 147 KMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 +MW+QEE+M EQEE+M++QEE+++ QEE+MR E Sbjct: 346 QMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379 Score = 186 bits (472), Expect = 2e-47 Identities = 102/198 (51%), Positives = 158/198 (79%), Gaps = 12/198 (6%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMW------EQEEKMQEQEEKM 56 +EE+++++E++++++EE MR+QEE+M+EQEE+MREQEE+M EQEE+ EQEE+M Sbjct: 239 QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM 298 Query: 57 WEQEEKMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQK--MWQQVEKM---R 110 EQEE+M EQEE+M EQ +++ EQ+E+M +Q+E++ E++E+M EQK MW+Q E+M Sbjct: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQE 358 Query: 111 EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 170 E+ + QEE++++QEE+M++QEE M +QEE+M++QEE+M EQ+E+M EQ+E+MREQEE+M Sbjct: 359 EQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMG 418 Query: 171 GQEEKMRDVEPAGGEAGE 188 Q+E+MR E GE E Sbjct: 419 EQKEQMRKQEEHMGEQKE 436 Score = 182 bits (461), Expect = 3e-46 Identities = 101/196 (51%), Positives = 154/196 (78%), Gaps = 10/196 (5%) Query: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 +RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE ++ EQE +++EQE +M EQ Sbjct: 138 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQ 197 Query: 60 EEKMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118 E +M EQEE+M EQ +++ +Q+E+M EQ+E++R++EE+M EQ+ +QV+K E+ + QEE Sbjct: 198 EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE--EQVQKQEEQVQKQEE 255 Query: 119 KMQEQEEKMQEQEEMMWEQEEKM------QEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 172 +M++QEE+M+EQEE M EQEE+M EQEE+ EQEE+MREQEE+MREQEE+M+ Q Sbjct: 256 QMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQ 315 Query: 173 EEKMRDVEPAGGEAGE 188 EE+MR+ E G+ E Sbjct: 316 EEQMREQEEQMGKQEE 331 Score = 177 bits (450), Expect = 5e-45 Identities = 97/184 (52%), Positives = 148/184 (80%), Gaps = 10/184 (5%) Query: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 +RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE +M EQE +M EQEE+M EQ Sbjct: 152 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQ 211 Query: 60 EEKMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118 EE+M +QEE+M EQ +++ +Q+E+M EQ+E+++++EE++++Q+ +Q+ K E+ + QEE Sbjct: 212 EEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQE--EQMRKQEEQMREQEE 269 Query: 119 KMQEQEEKM------QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 172 +M+EQEE+M EQEE EQEE+M+EQEE+M EQEE+MREQEE+MREQEE+M Q Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ 329 Query: 173 EEKM 176 EE+M Sbjct: 330 EEQM 333 Score = 162 bits (410), Expect = 2e-40 Identities = 90/205 (43%), Positives = 152/205 (74%), Gaps = 4/205 (1%) Query: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 +RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ Sbjct: 110 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 169 Query: 60 EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118 E ++ EQE ++ EQ+ ++ EQ+ +M EQ+ ++ E+EE+M EQ+ +Q++K E+ QEE Sbjct: 170 EGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE--EQMQKQEEQMGEQEE 227 Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178 +M++QEE+M EQEE + +QEE++Q+QEE+M +QEE+MREQEE+MREQEE+M Q+E+ Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ 287 Query: 179 VEPAGGEAGEGSPQDNPTAQEIMQL 203 E G + + Q+ ++ Q+ Sbjct: 288 EEQTGEQEEQMREQEEQMREQEEQM 312 Score = 159 bits (403), Expect = 2e-39 Identities = 93/207 (44%), Positives = 156/207 (75%), Gaps = 8/207 (3%) Query: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 +RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ Sbjct: 96 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 155 Query: 60 EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKTQ 116 E ++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E +M EQ+ M +Q E+M E Q Sbjct: 156 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGE----Q 211 Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 EE+MQ+QEE+M EQEE M +QEE+M EQEE++ +QEE++++QEE+MR+QEE+M+ QEE+M Sbjct: 212 EEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQM 271 Query: 177 RDVEPAGGEAGEGSPQDNPTAQEIMQL 203 R+ E + E + Q+ T ++ Q+ Sbjct: 272 REQEEQMLKQKEQTEQEEQTGEQEEQM 298 Score = 156 bits (395), Expect = 1e-38 Identities = 94/204 (46%), Positives = 153/204 (75%), Gaps = 9/204 (4%) Query: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 +RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ Sbjct: 89 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 148 Query: 60 EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKTQ 116 E ++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E ++REQ+ M +Q +M E Q Sbjct: 149 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGE----Q 204 Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 EE+M EQEE+MQ+QEE M EQEE+M++QEE+M EQEE++++QEE++++QEE+M+ QEE+M Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264 Query: 177 RDVEPAGGEAGEGS-PQDNPTAQE 199 R+ E E E Q T QE Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQE 288 Score = 154 bits (389), Expect = 6e-38 Identities = 87/182 (47%), Positives = 141/182 (77%), Gaps = 4/182 (2%) Query: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 +RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ Sbjct: 75 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 134 Query: 60 EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118 E ++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E ++REQ+ QV + + + QE Sbjct: 135 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEG 192 Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178 +M EQE +M EQEE M EQEE+MQ+QEE+M EQEE+MR+QEE+M EQEE++Q QEE+++ Sbjct: 193 QMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQK 252 Query: 179 VE 180 E Sbjct: 253 QE 254 Score = 147 bits (370), Expect = 1e-35 Identities = 83/182 (45%), Positives = 140/182 (76%), Gaps = 4/182 (2%) Query: 1 MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 +RE+E ++RE+E ++RE+E +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ Sbjct: 61 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120 Query: 60 EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118 E ++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E ++REQ+ QV + + + QE Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEG 178 Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178 +++EQE +++EQE M EQE +M EQEE+M EQEE+M++QEE+M EQEE+M+ QEE+M + Sbjct: 179 QVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE 238 Query: 179 VE 180 E Sbjct: 239 QE 240 Score = 85.5 bits (210), Expect = 4e-17 Identities = 50/152 (32%), Positives = 101/152 (66%), Gaps = 2/152 (1%) Query: 29 QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDE 88 +E +EK E +E++ E + E + + E + K+ + + ++ ++ EQ+ ++ EQ+ Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66 Query: 89 RLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKM 148 ++RE+E ++REQ+ QV + + + QE +++EQE +++EQE + EQE +++EQE ++ Sbjct: 67 QVREQEGQVREQE--GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 124 Query: 149 WEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 EQE ++REQE ++REQE +++ QE ++R+ E Sbjct: 125 REQEGQVREQEGQVREQEGQVREQEGQVREQE 156 >gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] Length = 523 Score = 172 bits (437), Expect = 2e-43 Identities = 96/210 (45%), Positives = 151/210 (71%), Gaps = 35/210 (16%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+EER+RE+E+++RE+EE +REQEE++ EQEE++REQEE++ EQEE++ EQEE++ E EE Sbjct: 196 RQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEE 255 Query: 62 KMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEE 118 ++ EQEE++ EQ+ RL EQ+E++ EQ+ERL E+EER+REQ ++ +Q E++RE QEE Sbjct: 256 RLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLRE----QEE 311 Query: 119 KMQEQEEKMQEQEEMMWEQE-----EKMQEQEEKMWEQEEKMREQE-------------- 159 ++ EQEE+++EQEE + EQE E++ E+ EK+ EQE + EQE Sbjct: 312 RLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEE 371 Query: 160 ----EKMREQEEKMQGQE-----EKMRDVE 180 E++R+Q+E++ QE E++R++E Sbjct: 372 LLEQERLRQQDERLWQQETLQELERLRELE 401 Score = 168 bits (426), Expect = 3e-42 Identities = 87/173 (50%), Positives = 131/173 (75%), Gaps = 23/173 (13%) Query: 8 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67 R +E+++RE+EE +REQEE+++EQEE++ EQEE++ EQEE+++EQEE++ EQEE++ E E Sbjct: 195 RRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHE 254 Query: 68 EKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKM 127 E RL EQ+E++ EQ+ERLRE+EER+ E QEE++ EQEE++ Sbjct: 255 E------RLCEQEERLCEQEERLREQEERLHE----------------QEERLCEQEERL 292 Query: 128 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 +EQEE + EQEE+++EQEE++ EQEE++REQEE++ EQ EK+ GQE + +VE Sbjct: 293 REQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ-EKLPGQERLLEEVE 344 Score = 142 bits (357), Expect = 3e-34 Identities = 82/236 (34%), Positives = 148/236 (62%), Gaps = 27/236 (11%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 +EER+ E+E+++RE+EE + EQEE++ EQEE++REQEE++ EQEE+++EQEE++ EQEE+ Sbjct: 260 QEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEER 319 Query: 63 MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQE 122 + EQEE++ EQ++LP Q E++ E+ E+L E+E R EQ+ + E++ E + E++ E Sbjct: 320 LREQEERLCEQEKLPGQ-ERLLEEVEKLLEQERRQEEQERLLERERLLE----EVEELLE 374 Query: 123 QEEKMQEQEEMMWEQE-----EKMQEQE-------EKMWEQEEKMREQEEKMREQEEKMQ 170 Q E++++Q+E +W+QE E+++E E E ++EQ + R E++ + + Sbjct: 375 Q-ERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTL 433 Query: 171 GQEEKMRDVEPAGGEAGEGSPQDNPTAQEIM-------QLFCGMK--NAQQCPGLG 217 E+++++++ +GG + A+ + CG Q+ PGLG Sbjct: 434 QLEQQVKELKKSGGAEEPRGSESAAAARPVAGAPVPQGAWMCGQAGWTPQEHPGLG 489 Score = 120 bits (301), Expect = 1e-27 Identities = 70/185 (37%), Positives = 115/185 (62%), Gaps = 21/185 (11%) Query: 26 EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW----EQEEKMWEQEEKMWEQQ-RLPEQK 80 E++Q++ +R++ E + Q + E + + QEE++ EQEE++ EQ+ RL EQ+ Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQE 219 Query: 81 EKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEK 140 E++ EQ+ERLRE+EER+REQ EE++ EQEE+++E EE + EQEE+ Sbjct: 220 ERLCEQEERLREQEERLREQ----------------EERLCEQEERLREHEERLCEQEER 263 Query: 141 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEI 200 + EQEE++ EQEE++ EQEE++ EQEE+++ QEE++ + E E E + +E Sbjct: 264 LCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQ 323 Query: 201 MQLFC 205 + C Sbjct: 324 EERLC 328 Score = 85.9 bits (211), Expect = 3e-17 Identities = 60/196 (30%), Positives = 107/196 (54%), Gaps = 17/196 (8%) Query: 3 EEERMREREKKMREEEEMMREQEE------KMQEQEEKMREQEEKMWEQEEKMQEQEEKM 56 +EER+RE+E+++ E+EE +REQEE K+ Q E++ E+ EK+ EQE + +EQE + Sbjct: 302 QEERLREQEERLCEQEERLREQEERLCEQEKLPGQ-ERLLEEVEKLLEQERRQEEQERLL 360 Query: 57 WEQEEKMWEQEEKMWEQQRLPEQKEKMWEQD-----ERLREKEERMREQKMWQQVEKMRE 111 + E++ E+ E++ EQ+RL +Q E++W+Q+ ERLRE E + + W+ + + R Sbjct: 361 --ERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERML--ELGWEALYEQRA 416 Query: 112 KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG 171 + ++ E++ + + + E+ + E ++ +E + E R Q M G Sbjct: 417 EPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPRGSESAAAARPVAGAPVPQGAWMCG 476 Query: 172 QEEKMRDVEPA-GGEA 186 Q P GGEA Sbjct: 477 QAGWTPQEHPGLGGEA 492 Score = 48.1 bits (113), Expect = 7e-06 Identities = 30/116 (25%), Positives = 69/116 (59%), Gaps = 9/116 (7%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQE-----QEEKMREQEEKMWEQEEKMQEQEEK 55 + E E++ E+E++ EE+E + E+E ++E ++E++R+Q+E++W+QE ++ E+ Sbjct: 340 LEEVEKLLEQERRQ-EEQERLLERERLLEEVEELLEQERLRQQDERLWQQE--TLQELER 396 Query: 56 MWEQEEKMWEQEEKMWEQQRLPEQK-EKMWEQDERLREKEERMREQKMWQQVEKMR 110 + E E + E ++EQ+ P E++ +++ + E++++E K E+ R Sbjct: 397 LRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPR 452 Score = 42.7 bits (99), Expect = 3e-04 Identities = 32/125 (25%), Positives = 60/125 (48%), Gaps = 12/125 (9%) Query: 93 KEERMREQKMWQQVEKMREKKKTQEEKMQEQE--------EKMQEQEEMMWEQEEKMQEQ 144 KEE+ E + Q++ + K K Q + E E++Q++ + ++ E + Q Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179 Query: 145 EEKMWEQEEKM----REQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEI 200 + E + + R QEE++REQEE+++ QEE++R+ E E E + +E Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQ 239 Query: 201 MQLFC 205 + C Sbjct: 240 EERLC 244 >gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sapiens] Length = 479 Score = 140 bits (352), Expect = 1e-33 Identities = 76/191 (39%), Positives = 135/191 (70%), Gaps = 22/191 (11%) Query: 8 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67 R +E+++RE+EE + EQEE++ EQEE++ EQEE++ EQEE+++EQEE++ EQEE++ EQE Sbjct: 195 RRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQE 254 Query: 68 EKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE--EKMQEQEE 125 E RL EQ+E++ EQ+ERL E+E+ ++++ ++VEK+ E+++ QE E++ E+E Sbjct: 255 E------RLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERER 308 Query: 126 KMQEQEEMMWEQEEKMQEQEEKMWEQE-----EKMREQE-----EKMREQEEKMQGQEEK 175 + E EE++ ++E++++Q+E++W+QE E++RE E E++RE E ++ E Sbjct: 309 LLDEVEELL--EQERLRQQDERLWQQETLRELERLRELERLRELERLRELERMLELGWEA 366 Query: 176 MRD--VEPAGG 184 + + EP G Sbjct: 367 LYEQRAEPRSG 377 Score = 135 bits (341), Expect = 2e-32 Identities = 71/200 (35%), Positives = 133/200 (66%), Gaps = 18/200 (9%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 +EER+ E+E+++ E+EE + EQEE++ EQEE++REQEE++ EQEE++ EQEE++ EQEE+ Sbjct: 204 QEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEER 263 Query: 63 MWEQEEKMWEQQRLP------EQKEKMWEQDERLREKEERMREQKMWQQVEKM--REKKK 114 + EQEE++ EQ++LP E+ EK+ EQ+ R E+E + +++ +VE++ +E+ + Sbjct: 264 LCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQERLR 323 Query: 115 TQEEKMQEQE-----EKMQEQE-----EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164 Q+E++ +QE E+++E E E + E E ++ E ++EQ + R E++ Sbjct: 324 QQDERLWQQETLRELERLRELERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNN 383 Query: 165 QEEKMQGQEEKMRDVEPAGG 184 + + E++++++E +GG Sbjct: 384 ENKSTLQLEQQVKELEKSGG 403 Score = 120 bits (301), Expect = 1e-27 Identities = 69/184 (37%), Positives = 129/184 (70%), Gaps = 12/184 (6%) Query: 5 ERMREREKKMREEEEMMREQEEKMQEQEEKM----REQEEKMWEQEEKMQEQEEKMWEQE 60 E++++ +R+E E + Q + E + + R QEE++ EQEE++ EQEE++ EQE Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQE 219 Query: 61 EKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERM--REQKMWQQVEKMREKKKTQ- 116 E++ EQEE++ EQ+ RL EQ+E++ EQ+ERL E+EER+ +E+++ +Q E++ E++K Sbjct: 220 ERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPG 279 Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 +E++ E+ EK+ EQE E++E++ E+E + E EE + ++E++R+Q+E++ Q+E + Sbjct: 280 QERLLEEVEKLLEQERRQ-EEQERLLERERLLDEVEELL--EQERLRQQDERL-WQQETL 335 Query: 177 RDVE 180 R++E Sbjct: 336 RELE 339 Score = 92.0 bits (227), Expect = 4e-19 Identities = 51/139 (36%), Positives = 86/139 (61%), Gaps = 18/139 (12%) Query: 47 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQV 106 E++Q++ + ++ E + Q + E ++ + Q+ERLRE+EER+ EQ Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR--RQEERLREQEERLHEQ------ 211 Query: 107 EKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 166 EE++ EQEE++ EQEE + EQEE+++EQEE++ EQEE++ EQEE++ EQE Sbjct: 212 ----------EERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQE 261 Query: 167 EKMQGQEEKMRDVEPAGGE 185 E++ QEE++ + E G+ Sbjct: 262 ERLCEQEERLCEQEKLPGQ 280 Score = 52.8 bits (125), Expect = 3e-07 Identities = 36/147 (24%), Positives = 79/147 (53%), Gaps = 22/147 (14%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 + E E++ E+E++ EE+E + E+E + E EE + ++E++++Q+E++W+QE Sbjct: 284 LEEVEKLLEQERRQ-EEQERLLERERLLDEVEELL---------EQERLRQQDERLWQQE 333 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 + E++ E +RL E ERLRE E + + W+ + + R + ++ E++ Sbjct: 334 --TLRELERLRELERLREL--------ERLRELERML--ELGWEALYEQRAEPRSGFEEL 381 Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEK 147 + + + E+ + E E+ +E + Sbjct: 382 NNENKSTLQLEQQVKELEKSGGAEEPR 408 Score = 48.9 bits (115), Expect = 4e-06 Identities = 27/101 (26%), Positives = 54/101 (53%) Query: 105 QVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164 +VE+++++ ++++ ++Q + E + QEE++ EQEE++ EQEE++ E Sbjct: 158 KVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHE 217 Query: 165 QEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEIMQLFC 205 QEE++ QEE++ + E E E + E + C Sbjct: 218 QEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLC 258 Score = 40.0 bits (92), Expect = 0.002 Identities = 27/100 (27%), Positives = 51/100 (51%), Gaps = 12/100 (12%) Query: 93 KEERMREQKMWQQVEKMREKKKTQEEKMQEQE--------EKMQEQEEMMWEQEEKMQEQ 144 KEE+ E + Q++ + K K Q + E E++Q++ + ++ E + Q Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179 Query: 145 EEKMWEQEEKM----REQEEKMREQEEKMQGQEEKMRDVE 180 + E + + R QEE++REQEE++ QEE++ + E Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQE 219 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 123 bits (308), Expect = 2e-28 Identities = 60/179 (33%), Positives = 124/179 (69%), Gaps = 6/179 (3%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKMQEQEEKMWEQE 60 RE+ R++ERE++ REEEE+ +E+E+ + E+ E R QE E+ + +EE++Q++EE++ +E Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 + ++E+ +++ E++E E+++ LRE+ E+ R Q++ +Q + E ++ +E+ + Sbjct: 1098 PEKRRRQER---ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLL 1154 Query: 121 QEQEEKMQEQE-EMMWEQEEKMQEQEEKMW-EQEEKMREQEEKMREQEEKMQGQEEKMR 177 +E+ EK + QE E + +EE++Q++EE++ E++EK R++ E+ +EE++Q Q+ K R Sbjct: 1155 REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213 Score = 119 bits (299), Expect = 2e-27 Identities = 62/184 (33%), Positives = 123/184 (66%), Gaps = 7/184 (3%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKMQEQEEKMWEQE 60 RE+ R +E+E++ REEE++ +E+E+ ++E+ EK R QE E+ + +++K+Q++EE++ +E Sbjct: 918 REKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 + ++E+ +++ E++E E+++ LRE+ E+ R Q+ +Q K E ++ +E+ + Sbjct: 978 PEKRRRQER---EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034 Query: 121 QEQEEK--MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE-EKMREQEEKMQGQEEKMR 177 +E+ EK +QE+E E+EE QE+E+ + E+ E R QE E+ +EE++Q +EE++ Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094 Query: 178 DVEP 181 EP Sbjct: 1095 REEP 1098 Score = 119 bits (299), Expect = 2e-27 Identities = 64/183 (34%), Positives = 120/183 (65%), Gaps = 7/183 (3%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKMQEQEEKMWEQEE 61 E+ R +EREKK REEEE+ +E+E+ ++E+ EK R QE E+ + +++++Q++EE++ +E Sbjct: 979 EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER 1038 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121 + +E+ +++ E++E E+++ L E+ E R Q++ +Q K E ++ +E+ ++ Sbjct: 1039 EKRRLQER---ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR 1095 Query: 122 EQEEK--MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE-EKMREQEEKMQGQEEKMRD 178 E+ EK QE+E E+EE QE+E+ + E+ EK R QE E+ +EE++Q +EE++ Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155 Query: 179 VEP 181 EP Sbjct: 1156 EEP 1158 Score = 113 bits (282), Expect = 2e-25 Identities = 62/196 (31%), Positives = 130/196 (66%), Gaps = 17/196 (8%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKMQEQEEKMWEQE 60 RE+ R +E E++ R+++E+ +E+E+ ++E+ EK R QE E+ + +EE++Q++EE++ +E Sbjct: 1008 REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEE 1067 Query: 61 ---------EKMWEQEEKMW--EQQRLPEQKEKM--WEQDERLREKEERMREQKMWQQVE 107 E+ + +EE++ E+Q L E+ EK E++ + RE+EE +E++ + E Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127 Query: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQE-EKMWEQEEKMREQEEKM--RE 164 + + +++ E + +E+EE QE+E+++ E+ EK + QE E+ + +EE+++++EE++ E Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187 Query: 165 QEEKMQGQEEKMRDVE 180 QE++ Q +E + R+ E Sbjct: 1188 QEKRRQERERQYREEE 1203 Score = 109 bits (273), Expect = 2e-24 Identities = 59/189 (31%), Positives = 120/189 (63%), Gaps = 17/189 (8%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKMQEQEEKMW--E 58 RE+ R +E E++ REEEE+ +E+E+ ++E+ EK R QE E+ + +EE++Q++EE++ E Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187 Query: 59 QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLR---------EKEERMREQKMWQQVEKM 109 QE++ E+E + E++ L QK K +DE R EKE +R+ K++ + + Sbjct: 1188 QEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGREN 1247 Query: 110 REKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 169 + ++ ++ ++++++ + Q+ + ++ EQ+E+ +EQE + W+Q ++ +EE++ +E+K Sbjct: 1248 EQFRQLEDSQLRDRQSQ-QDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQK- 1305 Query: 170 QGQEEKMRD 178 E K RD Sbjct: 1306 ---EAKRRD 1311 Score = 108 bits (270), Expect = 4e-24 Identities = 56/193 (29%), Positives = 132/193 (68%), Gaps = 18/193 (9%) Query: 3 EEERMRER---------EKKMREEEEMMREQEEKMQ--EQEEKMREQEEKMWEQEEKMQE 51 EEER R R ++++R+E+++++E+EE++Q E+E++ R+++E+ + +EE++Q+ Sbjct: 879 EEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQ 938 Query: 52 QEEKMW--EQEEKMWEQEEKMWEQQRLPEQKEK--MWEQDERLR--EKEERMREQKMWQQ 105 +EE++ E+E++ ++ E+ + + + +QKE+ + E+ E+ R E+E++ RE++ QQ Sbjct: 939 EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998 Query: 106 VEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQE-EKMREQEEKMRE 164 E+ +++ ++ + QE E + ++++E+ E+E+ ++E+ EK QE E+ +EE++++ Sbjct: 999 EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ 1058 Query: 165 QEEKMQGQEEKMR 177 +EE++ G+E + R Sbjct: 1059 EEEQLLGEERETR 1071 Score = 108 bits (269), Expect = 5e-24 Identities = 62/199 (31%), Positives = 126/199 (63%), Gaps = 22/199 (11%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ---EEKMWE 58 RE + ++++++R E+++ R+QEE+ +EQ+E+ REQ+E+ +QEE+ ++Q E++ Sbjct: 288 RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR 347 Query: 59 QEEKMWEQEEKMWEQQRLPEQKEKMWEQ----------DERLREKEERMREQKMWQQVEK 108 +++ EQEE+ EQQ EQ+E+ EQ +++LR +++ REQ++ ++ + Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 407 Query: 109 MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKM-WEQEEK----MREQEEKMR 163 RE++ +E++++ +++ +EQEE EQ+ + + +E+++ EQEE+ RE+E + Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467 Query: 164 EQEEKMQ----GQEEKMRD 178 EQE + Q QEE+ R+ Sbjct: 468 EQERRKQQLKRDQEEERRE 486 Score = 107 bits (267), Expect = 9e-24 Identities = 56/184 (30%), Positives = 123/184 (66%), Gaps = 9/184 (4%) Query: 3 EEERMREREKK-MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 EEE++R+ E++ +R E + +Q+++++ +++ R+QEE+ EQ+E+ +EQ+E+ +QEE Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333 Query: 62 KMWEQ----EEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE 117 + +Q +E+ EQQ EQ+E+ EQ R RE+EE REQ++ ++ + RE++ +E Sbjct: 334 RREQQLRREQEERREQQLRREQEEERREQQLR-REQEEERREQQLRREQQLRREQQLRRE 392 Query: 118 EKMQEQEEKMQEQE---EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 174 ++++ +++ +EQ+ E +E++++ +++ EQEE+ EQ+ + +E++++ ++E Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452 Query: 175 KMRD 178 + RD Sbjct: 453 ERRD 456 Score = 105 bits (263), Expect = 3e-23 Identities = 56/190 (29%), Positives = 119/190 (62%), Gaps = 14/190 (7%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKMQEQEEKMWEQE 60 RE R +E E++ R+EEE+ +E+E+ ++E+ EK R QE E+ +EE++Q++EE++ +E Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 + ++E +++ E++E E+++ LRE+ E+ R Q++ +Q + E ++ +E+ + Sbjct: 1128 REKRRRQEL---ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL 1184 Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR---------EQEEKMREQEEKMQG 171 +E++EK +++ E + +EE++Q Q+ K ++E R E+E +R+ + +G Sbjct: 1185 REEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKG 1244 Query: 172 QE-EKMRDVE 180 +E E+ R +E Sbjct: 1245 RENEQFRQLE 1254 Score = 103 bits (258), Expect = 1e-22 Identities = 59/184 (32%), Positives = 119/184 (64%), Gaps = 13/184 (7%) Query: 1 MREEERMREREKKMREEE-------EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 53 ++EEE R+RE + EE+ E+ RE++E+ Q+Q+ REQ+ + ++EE+ ++QE Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319 Query: 54 EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113 E+ +QE + EQ+E+ EQQ EQ+E+ EQ R RE+EE REQ++ ++ E+ R ++ Sbjct: 320 ERREQQERR--EQQEERREQQLRREQEERR-EQQLR-REQEEERREQQLRREQEEERREQ 375 Query: 114 KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ--EEKMWEQEEKMREQEEKMREQEEKMQG 171 + + E+ +E++++ ++++ EQ+ + ++Q E+ +E+++R +++ REQEE+ Sbjct: 376 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435 Query: 172 QEEK 175 Q+ + Sbjct: 436 QKHE 439 Score = 103 bits (258), Expect = 1e-22 Identities = 59/207 (28%), Positives = 127/207 (61%), Gaps = 20/207 (9%) Query: 2 REEERMREREKKMREEEEMMREQEEKM---QEQEEKMREQEEKM--WEQEEKMQEQEEKM 56 RE++ +R++K REEE++++E EE+ QE++ K RE+E+++ E+E K ++E+++ Sbjct: 1657 REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQL 1716 Query: 57 WEQE-EKMWEQEEKM-----WEQQRLPEQKEKMWEQDERLREKEE----RMREQKMWQQV 106 QE E+ + +EE++ EQ R E+ K+ E+++ E+EE R + +++ Sbjct: 1717 RRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776 Query: 107 EKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEK----MWEQEE-KMREQEEK 161 E++R++++ Q+ + QE + K +E+E++ E+EE+ +++ WE+E+ ++ EQE++ Sbjct: 1777 EQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836 Query: 162 MREQEEKMQGQEEKMRDVEPAGGEAGE 188 +R++ ++ EE+ E + E E Sbjct: 1837 LRQERDRQYRAEEQFATQEKSRREEQE 1863 Score = 103 bits (257), Expect = 1e-22 Identities = 60/199 (30%), Positives = 121/199 (60%), Gaps = 26/199 (13%) Query: 2 REEERMREREKKMREEEEMM----REQEEKMQEQEEKMRE--------QEEKMWEQEEKM 49 R+ + +ERE++ EEE++ E EE E++ + RE +EEK ++ E+ Sbjct: 175 RQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQ 234 Query: 50 ----QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKE------ERMRE 99 QE+EEK W + E + +EE+ +++ P+++ ++ E++E+LR+ E ER E Sbjct: 235 DRVFQEEEEKEWRKRETVLRKEEEKLQEEE-PQRQRELQEEEEQLRKLERQELRRERQEE 293 Query: 100 QKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ---EEKMWEQEEKMR 156 ++ Q++ + ++ ++ QEE+ +EQ+E+ +EQ+E +QEE+ ++Q E++ +++ R Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353 Query: 157 EQEEKMREQEEKMQGQEEK 175 EQEE+ REQ+ + + +EE+ Sbjct: 354 EQEEERREQQLRREQEEER 372 Score = 103 bits (257), Expect = 1e-22 Identities = 70/202 (34%), Positives = 124/202 (61%), Gaps = 28/202 (13%) Query: 2 REEERMR-EREKKMREEEEMMREQEE---KMQEQEEKMREQE-------EKMWEQEEKM- 49 REE+R R E ++K REEE++++E+EE + QE++ K RE+E K E+E+++ Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLR 1384 Query: 50 -QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERL--REKEERMREQKMWQQV 106 QE+E K ++E+++ QE EQQ ++ K E++++L +E++ + RE++ QQV Sbjct: 1385 RQERERKFLKEEQQLRCQER---EQQLRQDRDRKFREEEQQLSRQERDRKFREEE--QQV 1439 Query: 107 EKMREKKKTQEEKM---QEQEEKMQEQEEMMWEQEEKM---QEQEEKMWEQEEKMREQE- 159 + ++K EE+ QE+ K +E+E+++ E+EE+ QE++ K E+E+++R QE Sbjct: 1440 RRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQER 1499 Query: 160 -EKMREQEEKMQGQEEKMRDVE 180 K REQE + Q E K + E Sbjct: 1500 DRKFREQELRSQEPERKFLEEE 1521 Score = 103 bits (256), Expect = 2e-22 Identities = 64/207 (30%), Positives = 123/207 (59%), Gaps = 19/207 (9%) Query: 1 MREEERMR-EREKKMREEEEMMREQEEKM---QEQEEKMREQEEKMWEQE--EKMQEQEE 54 + EE+++R ER +K REEE++++E+EE+ QE++ K E+E+++ QE K +EQE Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL 1508 Query: 55 KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKE----ERMREQKMWQQVEKMR 110 + E E K E+E+++ QQR + K +++++LR +E R + +++ E++R Sbjct: 1509 RSQEPERKFLEEEQQLHRQQR----QRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLR 1564 Query: 111 EKKKTQEEKMQEQEEK--MQEQEEMMWEQEEKMQEQEEKMWEQE---EKMREQEEKMREQ 165 ++++ Q+ QE++ K ++EQ+ EQE K E E+++ QE + +E++ K RE Sbjct: 1565 QEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRED 1624 Query: 166 EEKMQGQEEKMRDVEPAGGEAGEGSPQ 192 E+ +Q +EE+ + + E PQ Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQ 1651 Score = 102 bits (253), Expect = 4e-22 Identities = 61/193 (31%), Positives = 121/193 (62%), Gaps = 21/193 (10%) Query: 3 EEERMREREKKMREEEEMMREQE----EKMQEQEEKMRE---QEEKMWEQEEKMQEQ--- 52 EE+ R+RE +R+EEE ++E+E ++QE+EE++R+ QE + QEE+ Q+Q Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR 301 Query: 53 --EEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR 110 ++ +QEE+ EQ+E+ EQQ EQ+E+ EQ R RE+EER +Q +Q E+ R Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQQEERREQQLR-REQEERREQQLRREQEEERR 360 Query: 111 EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ--------EEKMWEQEEKMREQEEKM 162 E++ +E++ + +E++++ ++++ EQ+ + ++Q E+ +E+++R +++ Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420 Query: 163 REQEEKMQGQEEK 175 REQ+ + + +EE+ Sbjct: 421 REQQLRREQEEER 433 Score = 102 bits (253), Expect = 4e-22 Identities = 61/203 (30%), Positives = 121/203 (59%), Gaps = 27/203 (13%) Query: 2 REEERM---REREKKMREEEEMMREQEEK----------MQEQEEKMREQEEKMWEQEEK 48 REEE+ +ER++K REEE+ +R QE + QE+ K RE+E+ + E+EE+ Sbjct: 1417 REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1476 Query: 49 M---QEQEEKMWEQEEKMWEQE--EKMWEQQRLPEQKEKMWEQDERLREKEERMR----E 99 QE++ K E+E+++ QE K EQ+ ++ E+ + ++E+ +++R R E Sbjct: 1477 QLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQE 1536 Query: 100 QKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE-----KMQEQEEKMWEQEEK 154 ++ ++ E+ +++++ ++ K +E+E+ QE+EE ++E +++EQ+ + EQE K Sbjct: 1537 EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK 1596 Query: 155 MREQEEKMREQEEKMQGQEEKMR 177 E E+++R QE + Q ++E+ R Sbjct: 1597 FMEDEQQLRRQEGQQQLRQERDR 1619 Score = 101 bits (252), Expect = 5e-22 Identities = 66/206 (32%), Positives = 122/206 (59%), Gaps = 31/206 (15%) Query: 1 MREEERMREREKKMREEEEMMR--EQEEKMQEQEEKMREQ-EEKMWEQEEKMQEQEEKMW 57 + EE R R+K+ +E E+ EQ EK + E++ R++ +E++W Q ++ QE+EE+ Sbjct: 129 LEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRA 188 Query: 58 EQEE----KMWEQEEKMWEQQ-------------RLPEQKEKMWEQDERLREKEE---RM 97 E+E+ K E EE E+Q R +Q+++ QD +E+EE R Sbjct: 189 EEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRK 248 Query: 98 REQKMWQQVEKMREKKKTQEEKMQEQEEKMQ--EQEEMMWEQEEKMQEQEEKMWE----- 150 RE + ++ EK++E++ ++ ++QE+EE+++ E++E+ E++E+ Q+Q+ E Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308 Query: 151 -QEEKMREQEEKMREQEEKMQGQEEK 175 QEE+ REQ+E+ REQ+E+ + QEE+ Sbjct: 309 KQEEERREQQEERREQQERREQQEER 334 Score = 101 bits (252), Expect = 5e-22 Identities = 50/189 (26%), Positives = 120/189 (63%), Gaps = 13/189 (6%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE--EKMWEQ 59 + E ++R E++ RE+ + E+E++ + ++ + RE+E + E+EE++Q +E +++ E+ Sbjct: 793 QRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEE 852 Query: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK----------EERMREQKMWQQVEKM 109 E+ + E +E+ Q++ +QK + ++ER R + E+ +EQ++ Q+ E+ Sbjct: 853 EDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE 912 Query: 110 REKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQE-EKMREQEEKMREQEEK 168 ++++ ++ + QEQE + +E+E++ E+E+ ++E+ EK QE E+ +++K++++EE+ Sbjct: 913 LQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972 Query: 169 MQGQEEKMR 177 + G+E + R Sbjct: 973 LLGEEPEKR 981 Score = 101 bits (251), Expect = 6e-22 Identities = 53/175 (30%), Positives = 115/175 (65%), Gaps = 7/175 (4%) Query: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 68 E EK+ R+ E ++R++EEK+QE+E + + + ++ EQ K++ QE + QEE+ +Q+ Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQ-QQQR 299 Query: 69 KMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQ 128 EQQ +Q+E+ EQ E RE++ER +Q+ ++ + RE+++ +E++++ ++E+ + Sbjct: 300 LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359 Query: 129 EQEEMMWEQEEKMQEQE---EKMWEQEEKMREQEEKMREQE---EKMQGQEEKMR 177 ++++ EQEE+ +EQ+ E+ +E+++R +++ REQ+ E+ +E+++R Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 414 Score = 101 bits (251), Expect = 6e-22 Identities = 60/199 (30%), Positives = 125/199 (62%), Gaps = 23/199 (11%) Query: 1 MREEERMREREKKMREEEEMMREQ----EEKMQEQEEKMREQEEKMWEQ--EEKMQEQEE 54 +R E+++R RE+++R E+++ REQ E++++ +++ REQEE+ EQ E++ +EQ Sbjct: 389 LRREQQLR-REQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447 Query: 55 KMWEQEEKMW---EQEEKMWEQQRLPEQKEKMWEQDER-----LREKEERMREQKMWQQV 106 K ++E + W E+E + EQ+R +Q ++ E++ R L E+E R ++++ QQ+ Sbjct: 448 KREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQL 507 Query: 107 EKMREKKKTQEEKMQEQEEKMQE----QEEMMWEQEEK----MQEQEEKMWEQEEKMREQ 158 + +E+++ Q K QE+EE++Q+ ++++ EQEE+ ++ +EEK EQE + + Sbjct: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567 Query: 159 EEKMREQEEKMQGQEEKMR 177 + + E+ +++ +EE+ R Sbjct: 568 KREQEERRDQLLKREEERR 586 Score = 101 bits (251), Expect = 6e-22 Identities = 57/202 (28%), Positives = 128/202 (63%), Gaps = 25/202 (12%) Query: 2 REEERMREREKKMREEEEMMREQEE------------KMQEQEEKMREQEEKMWEQEEKM 49 R ++R ++R++K REEE++ +E+EE +++EQ+ + +EQE K E E+++ Sbjct: 1545 RGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQL 1604 Query: 50 QEQE--EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVE 107 + QE +++ ++ ++ + ++E++ +++ EQ+ E+D + E+E ++R Q+ QQ+ Sbjct: 1605 RRQEGQQQLRQERDRKFREDEQLLQERE--EQQLHRQERDRKFLEEEPQLRRQEREQQLR 1662 Query: 108 KMREKKKTQEEKM----QEQEEKMQEQEEMMWEQEEKM--QEQEEKMWEQEEKMREQ--E 159 R++K +EE++ +EQ+ + QE++ E+E+++ QE+E K ++E+++R Q E Sbjct: 1663 HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELE 1722 Query: 160 EKMREQEE-KMQGQEEKMRDVE 180 K RE+E+ + + ++E++R E Sbjct: 1723 RKFREEEQLRQETEQEQLRRQE 1744 Score = 100 bits (249), Expect = 1e-21 Identities = 55/186 (29%), Positives = 120/186 (64%), Gaps = 10/186 (5%) Query: 2 REEERMREREKKMR----EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 57 REE++ + RE++ R EEE+ R++E ++++EEK++E+E + + ++ +EQ K+ Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282 Query: 58 EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE 117 QE + QEE+ +Q+ EQ+ + +++ER ++EER +Q+ +Q E+ RE++ +E Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342 Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQ---EEKMREQEEKMREQE---EKMQG 171 ++ + +++ +EQEE EQ+ + +++EE+ +Q E+++R +++ REQ+ E+ Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402 Query: 172 QEEKMR 177 +E+++R Sbjct: 403 REQQLR 408 Score = 100 bits (249), Expect = 1e-21 Identities = 53/200 (26%), Positives = 130/200 (65%), Gaps = 25/200 (12%) Query: 2 REEERMREREKKMREEEEMMREQ---------EEKMQEQEEKMREQEEKMW--EQEEKMQ 50 R +E+ R+++ + + EEE R + +E+++++++ ++E+EE++ E+E++ + Sbjct: 864 RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR 923 Query: 51 EQEEKMWEQEEKMWEQEEKMWEQQ---RLPEQKEKMWEQDERLREKEERMREQKMWQQVE 107 +++E+ + +EE++ ++EE++ ++ R +++E+ + +D++L++KEE++ ++ ++ Sbjct: 924 QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983 Query: 108 KMREKKKTQEEKMQEQEEKM----------QEQEEMMWEQEEKMQEQEEKMWEQEEKMRE 157 + REKK +EE++Q++EE++ QE E +++E QE+E+ + E+ EK R Sbjct: 984 QEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRL 1043 Query: 158 QE-EKMREQEEKMQGQEEKM 176 QE E+ +EE++Q +EE++ Sbjct: 1044 QERERQYREEEELQQEEEQL 1063 Score = 100 bits (249), Expect = 1e-21 Identities = 59/183 (32%), Positives = 116/183 (63%), Gaps = 19/183 (10%) Query: 3 EEERMREREKKMREEEEMMREQEE---KMQEQEEKMREQEEKMWEQEE---KMQEQEEKM 56 E++ + R++K +EE++++RE+ E + QE + K RE+E+ + E+EE + QE++ K Sbjct: 1303 EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362 Query: 57 WEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116 E+E + EQ K E+ EQ+ + E++ + ++E+++R Q+ QQ+ + R++K + Sbjct: 1363 REEELRHQEQGRKFLEE----EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE 1418 Query: 117 EEKM---QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-EQEEKMREQEEKMQGQ 172 EE+ QE++ K +E+ EQ+ + QE+E K E+E+++R E+ K RE+E+ +Q + Sbjct: 1419 EEQQLSRQERDRKFREE-----EQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473 Query: 173 EEK 175 EE+ Sbjct: 1474 EEQ 1476 Score = 99.8 bits (247), Expect = 2e-21 Identities = 57/201 (28%), Positives = 118/201 (58%), Gaps = 23/201 (11%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQE--EKMREQEEKMWEQEEKMQEQEEKM---- 56 EE+ R R+++ RE+E E+EE++Q +E ++++E+E+ + E +E+ + QE++ Sbjct: 815 EEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKW 874 Query: 57 -WEQEEKMWEQEEKMWEQQRLPEQKEK-----MWEQDERLREKEERMREQKMWQQVEKMR 110 W+ EE+ + ++ + L EQ K E++E RE+ E+ R Q+ +Q + Sbjct: 875 RWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEE 934 Query: 111 EKKKTQEEKMQEQEEKMQEQE-EMMWEQEEKMQEQEEKMW----------EQEEKMREQE 159 + ++ +E+ ++E+ EK + QE E + +++K+Q++EE++ E+E+K RE+E Sbjct: 935 QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE 994 Query: 160 EKMREQEEKMQGQEEKMRDVE 180 E +E+E+ ++ + EK R E Sbjct: 995 ELQQEEEQLLREEREKRRRQE 1015 Score = 98.6 bits (244), Expect = 4e-21 Identities = 60/175 (34%), Positives = 110/175 (62%), Gaps = 13/175 (7%) Query: 3 EEERMREREKKMREEE--EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ---EEKMW 57 +EE RER K+ EEE E +E++++ ++E+ REQ K E+EE++Q++ E+++ Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539 Query: 58 EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE 117 ++E+ EQ K E++RL +++ +++RL+ ++E R+Q + ++ E+ +++ K ++ Sbjct: 540 REQEERREQLLKREEEKRLEQER-----REQRLKREQEERRDQLLKREEERRQQRLKREQ 594 Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 172 E+ EQ K +E E + EQEE+ +EQ K E EE+ R+Q K EQEE+ Q Q Sbjct: 595 EERLEQRLKREEVERL--EQEER-REQRLKREEPEEERRQQLLKSEEQEERRQQQ 646 Score = 98.6 bits (244), Expect = 4e-21 Identities = 71/189 (37%), Positives = 110/189 (58%), Gaps = 15/189 (7%) Query: 2 REEERMREREKKMREE--EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 REEER ++R K+ +EE E+ ++ +E + EQEE+ REQ K E EE+ ++Q K EQ Sbjct: 581 REEERRQQRLKREQEERLEQRLKREEVERLEQEER-REQRLKREEPEEERRQQLLKSEEQ 639 Query: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERL-----REKEERMREQKMWQQV-EKMREKK 113 EE+ +Q + EQQ EQ+ K E++ERL RE EE REQ++ ++ E+ RE+ Sbjct: 640 EERRQQQLRR--EQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERI 697 Query: 114 KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE----KM 169 K++ K Q Q E + + + QE + + EQEEK R +E +++ QEE + Sbjct: 698 KSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQ 757 Query: 170 QGQEEKMRD 178 Q +EE+ RD Sbjct: 758 QQEEEQRRD 766 Score = 98.6 bits (244), Expect = 4e-21 Identities = 61/205 (29%), Positives = 115/205 (56%), Gaps = 27/205 (13%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKMQEQEEKMWEQE- 60 E+ R +ERE++ REEEE+ +E+E+ ++E+ EK R QE E+ + +EE++Q++EE++ +E Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158 Query: 61 --------EKMWEQEEKMW--EQQRLPEQKEKMWEQDERLREKEERMREQKMWQQV--EK 108 E+ + +EE++ E+Q L E++EK ++ ER +EE ++ QK Q+ E Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218 Query: 109 MREKKKTQEEKMQE-------------QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM 155 R K Q E +E + E+ ++ E+ + Q+ + + EQ+E+ Sbjct: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD 1278 Query: 156 REQEEKMREQEEKMQGQEEKMRDVE 180 REQE + +Q ++ +EE++ E Sbjct: 1279 REQERRRWQQRDRHFPEEEQLEREE 1303 Score = 98.6 bits (244), Expect = 4e-21 Identities = 58/196 (29%), Positives = 121/196 (61%), Gaps = 23/196 (11%) Query: 3 EEERMR--EREKKMREEEEMMREQEEK---MQEQEEKMREQEEKMWEQEEKMQEQEEKMW 57 EE+++R ER++K REEE+ +R QE + +QE+++ R++ E+ + +EE+++++ E+ Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ-- 1737 Query: 58 EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLRE--KEERMREQKMWQQVE------KM 109 EQ + + + E+Q PE++E+ + ER R+ +EE++R+++ QQ+ K Sbjct: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKF 1797 Query: 110 REKKKTQEEKMQEQEEKMQEQEEMMWEQEE-KMQEQEEKM-------WEQEEKMREQEEK 161 RE+++ ++E+ ++Q Q + WE+E+ +++EQE+++ + EE+ QE+ Sbjct: 1798 REEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKS 1857 Query: 162 MREQEEKMQGQEEKMR 177 RE++E Q +E+K R Sbjct: 1858 RREEQELWQEEEQKRR 1873 Score = 97.8 bits (242), Expect = 7e-21 Identities = 63/189 (33%), Positives = 116/189 (61%), Gaps = 24/189 (12%) Query: 1 MREEERMRE---REKKMREEEEMMREQEEKMQEQEE----KMREQEEKMWEQEEKMQEQE 53 + EEER + RE+++R E+E REQ K QE+EE ++R +++ EQEE+ +E Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER---RE 547 Query: 54 EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113 + + +EEK EQE + +QRL ++E+ +D+ L+ +EER +++ +Q E++ ++ Sbjct: 548 QLLKREEEKRLEQERR---EQRLKREQEE--RRDQLLKREEERRQQRLKREQEERLEQRL 602 Query: 114 KTQEEKMQEQEE------KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167 K +E + EQEE K +E EE +Q K +EQEE+ +++++R ++++ REQ Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER---RQQQLRREQQERREQRL 659 Query: 168 KMQGQEEKM 176 K + +EE++ Sbjct: 660 KREEEEERL 668 Score = 97.4 bits (241), Expect = 9e-21 Identities = 63/216 (29%), Positives = 128/216 (59%), Gaps = 37/216 (17%) Query: 2 REEERM--REREKKMREEEEMMREQEE--KMQEQEEKMREQEEKMWEQEEKM--QEQEEK 55 REE+++ +ER++K EEE+ +R QE K +EQE + +E E K E+E+++ Q+++ K Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRK 1532 Query: 56 MWEQEEKMWEQEE----------KMWEQQRLPEQKEKMW----EQDERLREKEERMREQK 101 ++E+++ QE K E+++L +++E+ E+D + R +E+++R Q+ Sbjct: 1533 FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQE 1592 Query: 102 M---WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKM---QEQEEKMWEQEEKM 155 + + E+ +++ Q++ QE++ K +E E+++ E+EE+ QE++ K E+E ++ Sbjct: 1593 QERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQL 1652 Query: 156 REQE----------EKMREQEEKMQ-GQEEKMRDVE 180 R QE K RE+E+ +Q G+E+++R E Sbjct: 1653 RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQE 1688 Score = 97.4 bits (241), Expect = 9e-21 Identities = 57/203 (28%), Positives = 120/203 (59%), Gaps = 18/203 (8%) Query: 1 MREEERMR--EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 58 ++EE+++R E E+K REEE++ +E E++ ++E+ R K+ E+E+ E+EE+ Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR----KILEEEQLRPEREEQQLR 1765 Query: 59 QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118 ++E+ + E+ +Q EQ+ + E D + RE+E+ +E++ Q + R+ K EE Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE 1825 Query: 119 ---KMQEQEEKMQEQEEMMWEQE------EKMQEQEEKMWEQEEKMREQEEKMREQEE-- 167 +++EQE++++++ + + E EK + +E+++W++EE+ R QE + + +EE Sbjct: 1826 EQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHI 1885 Query: 168 -KMQGQEEKMRDVEPAGGEAGEG 189 + Q +E++ R V + G+G Sbjct: 1886 RRQQKEEQRHRQVGEIKSQEGKG 1908 Score = 97.1 bits (240), Expect = 1e-20 Identities = 62/186 (33%), Positives = 119/186 (63%), Gaps = 13/186 (6%) Query: 2 REEERMREREKKMREEEEMMREQEEK---MQEQEEKMREQEEKMWEQEEKMQEQEEK-MW 57 +EEER ++ ++ R E+ + REQEE+ ++ +EE R ++E+ +Q ++ QE+E + W Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488 Query: 58 ---EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKK 114 E+EE+ +QE + EQQ EQ+E+ EQ + +E+EER+ +Q++ + + RE+++ Sbjct: 489 LKLEEEERREQQERR--EQQLRREQEERR-EQRLKRQEEEERL-QQRLRSEQQLRREQEE 544 Query: 115 TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 174 +E+ ++ +EEK EQE + + +E+ +++ ++EE+ R+Q K REQEE+++ Q Sbjct: 545 RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK-REQEERLE-QRL 602 Query: 175 KMRDVE 180 K +VE Sbjct: 603 KREEVE 608 Score = 96.7 bits (239), Expect = 2e-20 Identities = 56/190 (29%), Positives = 119/190 (62%), Gaps = 17/190 (8%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQ-----EQEEK-----MREQEEKMWEQEEKMQE 51 ++EE RE++++ RE++E +QEE+ + EQEE+ REQEE+ EQ+ + ++ Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368 Query: 52 QEEKMWEQ---EEKMWEQEEKMWEQQRLPEQ---KEKMWEQDERLREKEERMREQKMWQQ 105 +EE+ +Q E+++ +++ EQQ EQ +E+ ++++LR +++ REQ++ ++ Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428 Query: 106 VEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 165 E+ R ++K ++E+ +EQ K +++E W + E+ E+ E+ +++ R+QEE+ RE+ Sbjct: 429 QEEERHEQKHEQER-REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487 Query: 166 EEKMQGQEEK 175 K++ +E + Sbjct: 488 WLKLEEEERR 497 Score = 96.3 bits (238), Expect = 2e-20 Identities = 59/186 (31%), Positives = 122/186 (65%), Gaps = 22/186 (11%) Query: 2 REEERM--REREKKMREEEEMMREQEEKMQ---EQEEKMREQEEKMWEQEEKM---QEQE 53 REE+++ +ER++K EEE +R QE + Q +++ K RE+E+ + E EE+ QE++ Sbjct: 1631 REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690 Query: 54 EKMWEQEEKMWEQEEK---MWEQQRLPEQK-EKMWEQDERLREK--EERMREQKMWQQV- 106 K E+E+++ QE + + E+Q+L Q+ E+ + ++E+LR++ +E++R Q+ ++++ Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKIL 1750 Query: 107 --EKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164 E++R +++ Q+ + QE++ K +E+E++ E+EE Q+ + E + K RE EE++R+ Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE----QQLRSQESDRKFRE-EEQLRQ 1805 Query: 165 QEEKMQ 170 + E+ Q Sbjct: 1806 EREEQQ 1811 Score = 95.9 bits (237), Expect = 3e-20 Identities = 55/184 (29%), Positives = 114/184 (61%), Gaps = 8/184 (4%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R E+++R +++ R E+++ REQEE+ +EQ+ + +Q + + + Q + E+ +E+ Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREK-EERMREQKMWQQVEKMREKKKTQEE-K 119 ++ +++ EQQ EQ+ + +++ER +K E+ REQ++ ++ E+ R+ K +EE + Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465 Query: 120 MQEQEEKMQ----EQEEMMWEQEEKMQEQE--EKMWEQEEKMREQEEKMREQEEKMQGQE 173 EQE + Q +QEE E+ K++E+E E+ +E+++R ++E+ REQ K Q +E Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 525 Query: 174 EKMR 177 E+++ Sbjct: 526 ERLQ 529 Score = 95.9 bits (237), Expect = 3e-20 Identities = 66/240 (27%), Positives = 132/240 (55%), Gaps = 28/240 (11%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE----------QEEKMWEQEEKMQ 50 ++EEE + +++ R +E R+Q+ + Q +EE+ R QE+ EQ+ + Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908 Query: 51 EQEEKMWEQEEK--MWEQEEKMWEQQRLPEQKEKMWEQD---ERLREKEERMREQKMWQQ 105 E+EE E+ EK EQE + E+++L +++E++ ++ R +E+E + R+ K QQ Sbjct: 909 EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968 Query: 106 VEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKM----WE-----QEEKMR 156 E+ ++ ++ + QE+E+K +E+EE+ E+E+ ++E+ EK WE ++E + Sbjct: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ 1028 Query: 157 EQEEKMREQEEK--MQGQEEKMRDVEPAGGEAGE--GSPQDNPTAQEIMQLFCGMKNAQQ 212 E+E+ +RE+ EK +Q +E + R+ E E + G ++ QE+ + + + QQ Sbjct: 1029 EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ 1088 Score = 95.5 bits (236), Expect = 4e-20 Identities = 60/185 (32%), Positives = 112/185 (60%), Gaps = 13/185 (7%) Query: 2 REEERMREREKKMREEEEMMREQ---EEKMQEQEEKMREQ-----EEKMWEQEEKMQEQE 53 RE+E RE+ K +EEEE ++++ E++++ ++E+ REQ EEK EQE + Q + Sbjct: 509 REQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK 568 Query: 54 EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQV--EKMRE 111 + E+ +++ ++EE+ QQRL ++E+ EQ + E E +E++ Q++ E+ E Sbjct: 569 REQEERRDQLLKREEER-RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEE 627 Query: 112 KKKTQEEKMQEQEEKMQEQ--EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 169 +++ Q K +EQEE+ Q+Q E +E++++ +EE+ ++ RE EE+ REQE Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687 Query: 170 QGQEE 174 + QE+ Sbjct: 688 EEQEQ 692 Score = 95.5 bits (236), Expect = 4e-20 Identities = 55/184 (29%), Positives = 112/184 (60%), Gaps = 12/184 (6%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQ--EQEEKMREQEEKMWEQEEKMQEQE-EKMWE 58 +EEE +E E+ +REE E R QE + Q E+EE +E+E+ + E+ EK + QE E+ + Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141 Query: 59 QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118 +EE++ ++EE++ ++ PE++ + E + + RE+EE +E++ Q + + +EK++ + E Sbjct: 1142 EEEEVQQEEEQLLREE--PEKRRRQ-ELERQYREEEELQQEEE--QLLREEQEKRRQERE 1196 Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM----REQEEKMQGQEE 174 + +EE++Q Q+ ++E + + WE E++ ++ K+ RE E+ Q ++ Sbjct: 1197 RQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDS 1256 Query: 175 KMRD 178 ++RD Sbjct: 1257 QLRD 1260 Score = 95.5 bits (236), Expect = 4e-20 Identities = 63/213 (29%), Positives = 129/213 (60%), Gaps = 38/213 (17%) Query: 3 EEERMRERE----------KKMREEEEMMREQEEKMQ---EQEEKMREQEEKMWEQEE-- 47 +E+ ++ERE +K EEE +R QE + Q +++ K RE+E+ + E EE Sbjct: 1624 DEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ 1683 Query: 48 -KMQEQEEKMWEQEEKMWEQEEK---MWEQQRLPEQK-EKMWEQDERLRE--KEERMREQ 100 + QE++ K E+E+++ QE + + E+Q+L Q+ E+ + ++E+LR+ ++E++R Q Sbjct: 1684 LRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQ 1743 Query: 101 KMWQQV---EKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE---KMQEQEEKMWEQEEK 154 + ++++ E++R +++ Q+ + QE++ K +E+E++ E+EE + QE + K E+E+ Sbjct: 1744 ERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQL 1803 Query: 155 MREQEE----------KMREQEEKMQGQEEKMR 177 +E+EE K R +EE++Q +E++ R Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836 Score = 95.1 bits (235), Expect = 5e-20 Identities = 54/185 (29%), Positives = 109/185 (58%), Gaps = 15/185 (8%) Query: 3 EEERMRER---EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 + ER R+R +RE+ E EE+ Q ++ + E+EEK + ++ + ++E + + Sbjct: 776 KSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLE 835 Query: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT---- 115 EE+ ++ E+ Q+L E+++ + E ER R +E+R ++ WQ E+ + ++ T Sbjct: 836 EEEQLQRRERA---QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK 892 Query: 116 ---QEEKMQEQEEKMQEQEEMMWEQEEKMQEQE-EKMWEQEEKMREQEEK-MREQEEKMQ 170 QE+ +EQ+ +E+EE+ E+ EK + QE E+ + +EE+++++EE+ +RE+ EK + Sbjct: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 952 Query: 171 GQEEK 175 QE + Sbjct: 953 RQERE 957 Score = 94.4 bits (233), Expect = 8e-20 Identities = 61/201 (30%), Positives = 124/201 (61%), Gaps = 24/201 (11%) Query: 1 MREEERMREREKKMREEEEMMREQ----EEKMQEQEEKMREQE---EKMWEQEEKMQEQE 53 +R E+ RE+++R E+++ REQ E++++ +++ REQ+ E+ +E++++ ++ Sbjct: 364 LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 423 Query: 54 EKMWEQEEKMWEQ--EEKMWEQQRLPEQKEK---MWEQDERLREKEERMREQKMWQQVEK 108 + EQEE+ EQ E++ EQ+ EQ+E+ + ++E R ++ER ++Q Q E+ Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEE 483 Query: 109 MREK-KKTQEEKMQEQEEKMQEQ----EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 163 RE+ K +EE+ +EQ+E+ ++Q +E EQ K QE+EE++ ++++R +++ R Sbjct: 484 RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL---QQRLRSEQQLRR 540 Query: 164 EQEEK----MQGQEEKMRDVE 180 EQEE+ ++ +EEK + E Sbjct: 541 EQEERREQLLKREEEKRLEQE 561 Score = 94.4 bits (233), Expect = 8e-20 Identities = 58/199 (29%), Positives = 118/199 (59%), Gaps = 17/199 (8%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM---QEQEEKMW 57 + EE+R+R +E RE + + EQ+ + QE+E+++R+ ++ + +EE+ QE++ K Sbjct: 1377 LEEEQRLRRQE---RERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFR 1433 Query: 58 EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE 117 E+E+++ QE E++ L E+++ E+ + RE+E+ ++E++ Q + R++K +E Sbjct: 1434 EEEQQVRRQER---ERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE 1490 Query: 118 E---KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQ--EEKMREQEEKMREQE---EKM 169 E + QE++ K +EQE E E K E+E+++ Q + K ++E+++R QE ++ Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRR 1550 Query: 170 QGQEEKMRDVEPAGGEAGE 188 Q ++ K R+ E E E Sbjct: 1551 QDRDRKFREEEQLRQEREE 1569 Score = 94.4 bits (233), Expect = 8e-20 Identities = 59/213 (27%), Positives = 129/213 (60%), Gaps = 34/213 (15%) Query: 1 MREEERM--REREKKMREEEEMMREQE---EKMQEQEEKMREQEEKMWEQEE-------- 47 + EE+++ ++R++K +EE+ +R QE ++ Q+++ K RE+E+ E+EE Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577 Query: 48 ----KMQEQEEKMWEQEEKMWEQEEKMWE---QQRLPEQKEKMWEQDER-LREKEERM-- 97 +++EQ+ + EQE K E E+++ QQ+L +++++ + +DE+ L+E+EE+ Sbjct: 1578 DRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLH 1637 Query: 98 ---REQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE---KMQEQEEKMWEQ 151 R++K ++ ++R +++ Q+ + +++ K +E+E+++ E EE + QE++ K E+ Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLR-HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREE 1696 Query: 152 EEKMREQEEKMR----EQEEKMQGQEEKMRDVE 180 E+++R QE + + EQ+ + Q E K R+ E Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEE 1729 Score = 94.0 bits (232), Expect = 1e-19 Identities = 59/186 (31%), Positives = 107/186 (57%), Gaps = 14/186 (7%) Query: 2 REEERMREREKKMREE---EEMMREQEEKMQE---QEEKMREQEEKMWEQEEKMQEQEEK 55 RE+E R++ K EE + + REQEE++++ +EE R ++E+ EQ K +E EE+ Sbjct: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628 Query: 56 MWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT 115 +Q K EQEE+ QQ+L ++++ EQ + E+EER+ ++ + E+ RE++ Sbjct: 629 RRQQLLKSEEQEER--RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELA 686 Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMW------EQEEKMREQEEKMREQEEKM 169 +EE+ Q +E + W+ E + ++ K++ E + + +EQEEK R +E ++ Sbjct: 687 EEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL 746 Query: 170 QGQEEK 175 Q QEE+ Sbjct: 747 QWQEEE 752 Score = 93.6 bits (231), Expect = 1e-19 Identities = 59/218 (27%), Positives = 116/218 (53%), Gaps = 49/218 (22%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK-------MWEQEEKMQEQEEK 55 EE+ +RE ++K R+E E +EE++Q Q+ K R ++E WE E++ ++ K Sbjct: 1180 EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239 Query: 56 MW-------------------------------EQEEKMWEQEEKMWEQ--QRLPEQKEK 82 ++ EQ+E+ EQE + W+Q + PE+ Sbjct: 1240 VYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEE--- 1296 Query: 83 MWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE--- 139 EQ ER +KE + R++K ++ + +RE+++ ++ + QE + K +E+E+++ E+EE Sbjct: 1297 --EQLEREEQKEAKRRDRKSQEEKQLLREERE-EKRRRQETDRKFREEEQLLQEREEQPL 1353 Query: 140 KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 + QE++ K E+E + +EQ K E+E++++ QE + + Sbjct: 1354 RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERK 1391 Score = 93.2 bits (230), Expect = 2e-19 Identities = 53/197 (26%), Positives = 113/197 (57%), Gaps = 26/197 (13%) Query: 3 EEERMREREKKMREEEEMMREQEEKM--QEQEEKMREQEEKMWEQEEKMQEQEEK----- 55 + R + EK+ R E E+ ++EE+ Q+QEE+ R W+ EEK + ++ Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788 Query: 56 -MWEQEEKMWEQEEKMWEQQR-LPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113 + EQ E+ EE+ +QR LPE++EK ++R R++ ER +E + ++ E+++ ++ Sbjct: 789 PLREQRERQLRAEERQQREQRFLPEEEEK----EQRRRQRREREKELQFLEEEEQLQRRE 844 Query: 114 KTQ-----EEKMQEQEEKMQEQEE-----MMWEQEEKMQEQEEKMWEQ---EEKMREQEE 160 + Q E+ +QE +E+ + QE+ W+ EE+ + + ++ + +E++R++++ Sbjct: 845 RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQ 904 Query: 161 KMREQEEKMQGQEEKMR 177 ++E+EE++Q +E + R Sbjct: 905 LLQEEEEELQREEREKR 921 Score = 92.8 bits (229), Expect = 2e-19 Identities = 54/194 (27%), Positives = 115/194 (59%), Gaps = 17/194 (8%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ-------EEKMQEQEE 54 RE E+ R+ E + + ++ + + EQ+E+ REQE + W+Q EE+++ +E+ Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304 Query: 55 KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKK 114 K ++ ++ ++E+++ ++R E+K + E D + RE+E+ ++E++ + R++K Sbjct: 1305 KEAKRRDRKSQEEKQLLREER--EEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362 Query: 115 TQEE-KMQEQEEKMQEQEEMMWEQEEK----MQEQEEKMWEQEEKMR-EQEEKMREQEEK 168 +EE + QEQ K E+E+ + QE + +EQ+ + E+E+++R +++ K RE+E++ Sbjct: 1363 REEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ 1422 Query: 169 MQGQE--EKMRDVE 180 + QE K R+ E Sbjct: 1423 LSRQERDRKFREEE 1436 Score = 92.4 bits (228), Expect = 3e-19 Identities = 58/193 (30%), Positives = 118/193 (61%), Gaps = 14/193 (7%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQE----QEEKMREQEEKMWEQEEKMQEQEEKMW 57 R E+++R +++ RE+ +E+EE++Q+ +++ REQEE+ +E+ ++ +EEK Sbjct: 502 RREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER---REQLLKREEEKRL 558 Query: 58 EQEEKMWEQEEKMWEQQRLPE--QKEKMWEQDERLREKEERMREQKMWQQVEKM-REKKK 114 EQE + EQ K +++R + ++E+ Q RE+EER+ ++ ++VE++ +E+++ Sbjct: 559 EQERR--EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616 Query: 115 TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ--EEKMWEQEEKMREQEEKMREQEEKMQGQ 172 Q K +E EE+ ++Q EQEE+ Q+Q E+ +E++++ +EE+ R ++ + Sbjct: 617 EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREH 676 Query: 173 EEKMRDVEPAGGE 185 EE+ R+ E A E Sbjct: 677 EEERREQELAEEE 689 Score = 90.5 bits (223), Expect = 1e-18 Identities = 48/189 (25%), Positives = 123/189 (65%), Gaps = 14/189 (7%) Query: 1 MREEERMR--EREKKMREEEEM-MREQEEKM--QEQEEKMREQEEKM--WEQEEKMQEQE 53 ++EE+++R ERE+++R++ + RE+E+++ QE++ K RE+E+++ E+E K E+E Sbjct: 1393 LKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452 Query: 54 EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113 +++ ++ + + +EE++ +++ EQ+ E+D + E+E+++R Q+ ++ + + Sbjct: 1453 QQLRQERHRKFREEEQLLQERE--EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510 Query: 114 KTQEEKMQEQEEKM--QEQEEMMWEQEEKMQEQE---EKMWEQEEKMREQEEKMREQEEK 168 + E K E+E+++ Q+++ ++E++++ QE ++ +++ K RE+E+ +E+EE+ Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQ 1570 Query: 169 MQGQEEKMR 177 ++E+ R Sbjct: 1571 QLSRQERDR 1579 Score = 90.5 bits (223), Expect = 1e-18 Identities = 62/205 (30%), Positives = 121/205 (59%), Gaps = 22/205 (10%) Query: 3 EEERMR--EREKKMREEEEMMREQEEKMQ---EQEEKMREQEEKMWEQEEK-M--QEQEE 54 EE+++R E+E+K E+E+ +R QE + Q E++ K RE E+ + E+EE+ + QE++ Sbjct: 1584 EEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDR 1643 Query: 55 KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERM-----REQKMWQQVEKM 109 K E+E ++ QE EQQ ++ K E+++ L+E EE+ R++K ++ +++ Sbjct: 1644 KFLEEEPQLRRQER---EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700 Query: 110 REKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE--QEEKMR---- 163 R +++ ++ +EQ+ + QE E E+E+ QE E++ ++E+ R+ +EE++R Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760 Query: 164 EQEEKMQGQEEKMRDVEPAGGEAGE 188 EQ+ + Q ++ K R+ E E E Sbjct: 1761 EQQLRRQERDRKFREEEQLRQEREE 1785 Score = 89.4 bits (220), Expect = 3e-18 Identities = 71/224 (31%), Positives = 116/224 (51%), Gaps = 48/224 (21%) Query: 3 EEERMREREKKMREEEEMM-----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQ--EEK 55 +EER+ +R K REE E + REQ K +E EE+ R+Q K EQEE+ Q+Q E+ Sbjct: 594 QEERLEQRLK--REEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ 651 Query: 56 MWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ-----KMWQ-QVEK- 108 +E+++ +EE+ +QRL + E+ + E E++E+ RE+ WQ Q+E Sbjct: 652 QERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESE 711 Query: 109 ---------MREKKKTQEEKMQEQEEKMQEQE-EMMWEQEEK--MQEQEEK-------MW 149 R +K+ + + QEQEEK + +E E+ W++EE+ Q+QEE+ W Sbjct: 712 ADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQW 771 Query: 150 EQEEK-------------MREQEEKMREQEEKMQGQEEKMRDVE 180 + EEK +REQ E+ EE+ Q ++ + + E Sbjct: 772 QAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEE 815 Score = 89.0 bits (219), Expect = 3e-18 Identities = 66/234 (28%), Positives = 118/234 (50%), Gaps = 54/234 (23%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKM-----REQEEKMWEQEEKMQEQEEK 55 ++ EE+ R++++R E++ REQ K +E+EE++ RE EE+ EQE +EQE+ Sbjct: 634 LKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA 693 Query: 56 -----------MWEQEE-------KMWEQEEKMWEQQRLPEQKEK--------MWEQDER 89 W+ E K++ + K Q+R EQ+EK W+++ER Sbjct: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEER 753 Query: 90 L--REKEERMREQKMWQ-QVEKMREKKKT----------QEEKMQEQEEKMQEQEEMMWE 136 +++EE R WQ Q E+ E+ + Q E+ EE+ Q ++ + E Sbjct: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE 813 Query: 137 QEEKMQ--------EQEEKMWEQEEKM--REQEEKMREQEEKMQGQEEKMRDVE 180 +EEK Q E+E + E+EE++ RE+ ++++E+E+ +Q +E+ R E Sbjct: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867 Score = 89.0 bits (219), Expect = 3e-18 Identities = 51/182 (28%), Positives = 116/182 (63%), Gaps = 8/182 (4%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM--QEQEEKMWEQE 60 ++ER RE+E++ ++ + +EE+++ +E+K ++ ++ ++E+++ +E+EEK QE Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEE 118 +EE+ Q+R EQ + E+D + RE+E R +EQ K ++ +++R +++ ++ Sbjct: 1334 TDRKFREEEQLLQER-EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKF 1392 Query: 119 KMQEQEEKMQEQEEMM-WEQEEKMQEQEEKMWEQE--EKMREQEEKMREQEEKMQGQEEK 175 +EQ+ + QE+E+ + +++ K +E+E+++ QE K RE+E+++R QE + + EE+ Sbjct: 1393 LKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452 Query: 176 MR 177 + Sbjct: 1453 QQ 1454 Score = 88.6 bits (218), Expect = 4e-18 Identities = 56/184 (30%), Positives = 104/184 (56%), Gaps = 20/184 (10%) Query: 2 REEERMREREKKMRE-EEEMMREQEEKMQEQEEKMREQEEKMWEQEE----KMQEQEEKM 56 R+EE R E + R+ EEE + + +K QEQE ++ E EE+ +QE Q ++E++ Sbjct: 114 RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL 173 Query: 57 WEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116 W Q ++ E+EE+ E+++L K E+ EE++R +++ + K RE+K Q Sbjct: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEFP----DEEQLRRRELLELRRKGREEK--Q 227 Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 +++ + Q+ QE+EE W + E + +EE+ ++EE R++E +Q +EE++ Sbjct: 228 QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE---------LQEEEEQL 278 Query: 177 RDVE 180 R +E Sbjct: 279 RKLE 282 Score = 87.0 bits (214), Expect = 1e-17 Identities = 48/160 (30%), Positives = 98/160 (61%), Gaps = 5/160 (3%) Query: 22 REQEEKMQEQEEKMREQEEKM-WEQEEKM--QEQEEKMWEQEEKMWEQEEKMWE-QQRLP 77 +E + + QEQEEK R +E ++ W++EE+ Q+QEE+ W+ EEK +QRL Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785 Query: 78 EQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQ 137 + +++ +LR +E + REQ+ + E+ ++++ + E+ +E + +E++ E+ Sbjct: 786 ARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRER 845 Query: 138 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 +++QE+E+ + E +E+ R QE++ R+Q+ + Q +EE+ R Sbjct: 846 AQQLQEEEDGLQEDQERRRSQEQR-RDQKWRWQLEEERKR 884 Score = 85.9 bits (211), Expect = 3e-17 Identities = 53/203 (26%), Positives = 123/203 (60%), Gaps = 11/203 (5%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 +R E+++R RE++ R E+ + RE+E++++++ + R + E+ +++ ++ +EE+ Q+ Sbjct: 532 LRSEQQLR-REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER--RQQ 588 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMR-EQKMWQQVEKMREKKKTQEEK 119 EQEE++ +QRL ++ + EQ+ER ++ +R E++ QQ+ K E+++ ++++ Sbjct: 589 RLKREQEERL--EQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646 Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE---EKMQGQEEKM 176 ++ ++++ +EQ E+EE+++++ ++ E EE+ REQE EQE E+++ + K Sbjct: 647 LRREQQERREQRLKREEEEERLEQRLKR--EHEEERREQELAEEEQEQARERIKSRIPKW 704 Query: 177 RDVEPAGGEAGEGSPQDNPTAQE 199 + + +A + P QE Sbjct: 705 QWQLESEADARQSKVYSRPRKQE 727 Score = 71.6 bits (174), Expect = 6e-13 Identities = 44/169 (26%), Positives = 97/169 (57%), Gaps = 19/169 (11%) Query: 32 EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE------EKMWEQQRLPEQKEKMWE 85 EEK + K +++ QE++++ +E ++ E+E +K EQ+R + E+ E Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156 Query: 86 QDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQE 145 + ERL +++ + R++++W+Q ++ +E+++ + E+ Q Q K E EE E++ + +E Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216 Query: 146 E---KMWEQEEKMR----------EQEEKMREQEEKMQGQEEKMRDVEP 181 E K E++++ R E+E++ R++E ++ +EEK+++ EP Sbjct: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265 Score = 50.1 bits (118), Expect = 2e-06 Identities = 27/116 (23%), Positives = 64/116 (55%), Gaps = 7/116 (6%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 E+ ++ E+E+++R+E + EE+ QE+ RE++E +W++EE+ + QE + +EE Sbjct: 1826 EQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE-LWQEEEQKRRQERERKLREEH 1884 Query: 63 MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEER------MREQKMWQQVEKMREK 112 + Q+++ +++ E K + + RL E +R +++ +++ R + Sbjct: 1885 IRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQ 1940 Score = 35.0 bits (79), Expect = 0.057 Identities = 25/109 (22%), Positives = 52/109 (47%), Gaps = 6/109 (5%) Query: 111 EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 170 EK+ + K +++ QE+++ +E ++ Q +EE + +K +EQE ++ E EE+ + Sbjct: 98 EKRARCDGKESLLQDRRQEEDQRRFEPRDR-QLEEEPGQRRRQKRQEQERELAEGEEQSE 156 Query: 171 GQE-----EKMRDVEPAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQCP 214 QE ++ R E + E ++ A+E C ++ P Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFP 205 >gi|169208458 PREDICTED: similar to golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 432 Score = 113 bits (282), Expect = 2e-25 Identities = 67/190 (35%), Positives = 117/190 (61%), Gaps = 9/190 (4%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+EER+RE+E+++RE+EE + EQEE++ EQEE++REQEE++ EQE+ +E++ E+ E Sbjct: 196 RQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEK--LPGQERLLEEVE 253 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121 K+ +QE + EQ+RL E++ + E +E L ++ R +++++WQQ E +RE E+++ Sbjct: 254 KLLKQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQ-ETLREL-----ERLR 307 Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEP 181 E E ++ E ++EQ + + E++ E K Q E+ ++ EK G EE Sbjct: 308 ELERMLELGWEALYEQRAEPRSGFEEL-NNENKSTLQLEQQVKELEKSGGAEEPRGSESA 366 Query: 182 AGGEAGEGSP 191 A G+P Sbjct: 367 AAARPVPGAP 376 Score = 108 bits (270), Expect = 4e-24 Identities = 66/203 (32%), Positives = 124/203 (61%), Gaps = 29/203 (14%) Query: 5 ERMREREKKMREEEEMMREQEEKMQE-----------QEEKMREQEEKMWEQEEKMQEQE 53 E++++ +R+E E + Q + E QEE++REQEE++ EQEE++ EQE Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQE 219 Query: 54 EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113 E++ EQEE++ EQEE++ EQ++LP Q E++ E+ E+L ++E R EQ+ + RE+ Sbjct: 220 ERLCEQEERLREQEERLCEQEKLPGQ-ERLLEEVEKLLKQERRQEEQERLLE----RERL 274 Query: 114 KTQEEKMQEQEEKMQEQEEMMWEQE-----EKMQEQE-------EKMWEQEEKMREQEEK 161 + E++ EQ E++++Q+E +W+QE E+++E E E ++EQ + R E+ Sbjct: 275 LDEVEELLEQ-ERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEE 333 Query: 162 MREQEEKMQGQEEKMRDVEPAGG 184 + + + E++++++E +GG Sbjct: 334 LNNENKSTLQLEQQVKELEKSGG 356 Score = 108 bits (270), Expect = 4e-24 Identities = 65/198 (32%), Positives = 120/198 (60%), Gaps = 13/198 (6%) Query: 1 MREEERMREREKKMREEEEMM-----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 55 +R+E R+ + E M R QEE+++EQEE++REQEE++ EQEE++ EQEE+ Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEER 228 Query: 56 MWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM--REKK 113 + EQEE++ EQE K+ Q+RL E+ EK+ +Q+ R E+E + +++ +VE++ +E+ Sbjct: 229 LREQEERLCEQE-KLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQERL 287 Query: 114 KTQEEKMQEQE-----EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168 + Q+E++ +QE E+++E E M+ E + EQ + E++ + + + E++ Sbjct: 288 RQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQ 347 Query: 169 MQGQEEKMRDVEPAGGEA 186 ++ E+ EP G E+ Sbjct: 348 VKELEKSGGAEEPRGSES 365 Score = 60.5 bits (145), Expect = 1e-09 Identities = 28/86 (32%), Positives = 57/86 (66%) Query: 100 QKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 159 +++ + +R++ ++ ++Q + E Q + QEE+++EQEE++ EQEE++ EQE Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQE 219 Query: 160 EKMREQEEKMQGQEEKMRDVEPAGGE 185 E++ EQEE+++ QEE++ + E G+ Sbjct: 220 ERLCEQEERLREQEERLCEQEKLPGQ 245 >gi|154937324 hypothetical protein LOC440295 [Homo sapiens] Length = 432 Score = 113 bits (282), Expect = 2e-25 Identities = 67/190 (35%), Positives = 117/190 (61%), Gaps = 9/190 (4%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+EER+RE+E+++RE+EE + EQEE++ EQEE++REQEE++ EQE+ +E++ E+ E Sbjct: 196 RQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEK--LPGQERLLEEVE 253 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121 K+ +QE + EQ+RL E++ + E +E L ++ R +++++WQQ E +RE E+++ Sbjct: 254 KLLKQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQ-ETLREL-----ERLR 307 Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEP 181 E E ++ E ++EQ + + E++ E K Q E+ ++ EK G EE Sbjct: 308 ELERMLELGWEALYEQRAEPRSGFEEL-NNENKSTLQLEQQVKELEKSGGAEEPRGSESA 366 Query: 182 AGGEAGEGSP 191 A G+P Sbjct: 367 AAARPVPGAP 376 Score = 108 bits (270), Expect = 4e-24 Identities = 66/203 (32%), Positives = 124/203 (61%), Gaps = 29/203 (14%) Query: 5 ERMREREKKMREEEEMMREQEEKMQE-----------QEEKMREQEEKMWEQEEKMQEQE 53 E++++ +R+E E + Q + E QEE++REQEE++ EQEE++ EQE Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQE 219 Query: 54 EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113 E++ EQEE++ EQEE++ EQ++LP Q E++ E+ E+L ++E R EQ+ + RE+ Sbjct: 220 ERLCEQEERLREQEERLCEQEKLPGQ-ERLLEEVEKLLKQERRQEEQERLLE----RERL 274 Query: 114 KTQEEKMQEQEEKMQEQEEMMWEQE-----EKMQEQE-------EKMWEQEEKMREQEEK 161 + E++ EQ E++++Q+E +W+QE E+++E E E ++EQ + R E+ Sbjct: 275 LDEVEELLEQ-ERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEE 333 Query: 162 MREQEEKMQGQEEKMRDVEPAGG 184 + + + E++++++E +GG Sbjct: 334 LNNENKSTLQLEQQVKELEKSGG 356 Score = 108 bits (270), Expect = 4e-24 Identities = 65/198 (32%), Positives = 120/198 (60%), Gaps = 13/198 (6%) Query: 1 MREEERMREREKKMREEEEMM-----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 55 +R+E R+ + E M R QEE+++EQEE++REQEE++ EQEE++ EQEE+ Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEER 228 Query: 56 MWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM--REKK 113 + EQEE++ EQE K+ Q+RL E+ EK+ +Q+ R E+E + +++ +VE++ +E+ Sbjct: 229 LREQEERLCEQE-KLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQERL 287 Query: 114 KTQEEKMQEQE-----EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168 + Q+E++ +QE E+++E E M+ E + EQ + E++ + + + E++ Sbjct: 288 RQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQ 347 Query: 169 MQGQEEKMRDVEPAGGEA 186 ++ E+ EP G E+ Sbjct: 348 VKELEKSGGAEEPRGSES 365 Score = 60.5 bits (145), Expect = 1e-09 Identities = 28/86 (32%), Positives = 57/86 (66%) Query: 100 QKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 159 +++ + +R++ ++ ++Q + E Q + QEE+++EQEE++ EQEE++ EQE Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQE 219 Query: 160 EKMREQEEKMQGQEEKMRDVEPAGGE 185 E++ EQEE+++ QEE++ + E G+ Sbjct: 220 ERLCEQEERLREQEERLCEQEKLPGQ 245 >gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sapiens] Length = 432 Score = 112 bits (281), Expect = 2e-25 Identities = 67/190 (35%), Positives = 116/190 (61%), Gaps = 9/190 (4%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 R+EER+RE+E+++RE+EE + EQEE++ EQEE++ EQEE++ EQE+ +E++ E+ E Sbjct: 196 RQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEK--LPGQERLLEEVE 253 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121 K+ EQE + EQ+RL E++ + E +E L ++ R +++++WQQ E +RE E+++ Sbjct: 254 KLLEQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQ-ETLREL-----ERLR 307 Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEP 181 E E ++ E ++EQ + + E++ E K Q E+ ++ EK G EE Sbjct: 308 ELERMLELGWEALYEQRAEPRSGFEEL-NNENKSTLQLEQQVKELEKSGGAEEPRGSESA 366 Query: 182 AGGEAGEGSP 191 A G+P Sbjct: 367 AAARPVPGAP 376 Score = 111 bits (278), Expect = 5e-25 Identities = 67/203 (33%), Positives = 124/203 (61%), Gaps = 29/203 (14%) Query: 5 ERMREREKKMREEEEMMREQEEKMQE-----------QEEKMREQEEKMWEQEEKMQEQE 53 E++++ +R+E E + Q + E QEE++REQEE++ EQEE++ EQE Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQE 219 Query: 54 EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113 E++ EQEE++ EQEE++ EQ++LP Q E++ E+ E+L E+E R EQ+ + RE+ Sbjct: 220 ERLCEQEERLCEQEERLCEQEKLPGQ-ERLLEEVEKLLEQERRQEEQERLLE----RERL 274 Query: 114 KTQEEKMQEQEEKMQEQEEMMWEQE-----EKMQEQE-------EKMWEQEEKMREQEEK 161 + E++ EQ E++++Q+E +W+QE E+++E E E ++EQ + R E+ Sbjct: 275 LDEVEELLEQ-ERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEE 333 Query: 162 MREQEEKMQGQEEKMRDVEPAGG 184 + + + E++++++E +GG Sbjct: 334 LNNENKSTLQLEQQVKELEKSGG 356 Score = 60.1 bits (144), Expect = 2e-09 Identities = 28/86 (32%), Positives = 56/86 (65%) Query: 100 QKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 159 +++ + +R++ ++ ++Q + E Q + QEE+++EQEE++ EQEE++ EQE Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQE 219 Query: 160 EKMREQEEKMQGQEEKMRDVEPAGGE 185 E++ EQEE++ QEE++ + E G+ Sbjct: 220 ERLCEQEERLCEQEERLCEQEKLPGQ 245 Score = 45.8 bits (107), Expect = 3e-05 Identities = 32/128 (25%), Positives = 70/128 (54%), Gaps = 18/128 (14%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 + E E++ E+E++ EE+E + E+E + E EE + ++E++++Q+E++W+QE Sbjct: 249 LEEVEKLLEQERRQ-EEQERLLERERLLDEVEELL---------EQERLRQQDERLWQQE 298 Query: 61 EKMWEQEEKMWEQQRLPEQK-EKMWEQDERLREKEERMREQ-----KMWQQVEKMREKKK 114 + E++ E +R+ E E ++EQ R E + + ++ QQV+++ + Sbjct: 299 --TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGG 356 Query: 115 TQEEKMQE 122 +E + E Sbjct: 357 AEEPRGSE 364 Score = 40.4 bits (93), Expect = 0.001 Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 12/100 (12%) Query: 93 KEERMREQKMWQQVEKMREKKKTQEEKMQEQE--------EKMQEQEEMMWEQEEKMQEQ 144 KEE+ E + Q++ + K K Q + E E++Q++ + ++ E + Q Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179 Query: 145 EEKMWEQEEKM----REQEEKMREQEEKMQGQEEKMRDVE 180 + E + + R QEE++REQEE+++ QEE++ + E Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQE 219 >gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapiens] Length = 693 Score = 104 bits (260), Expect = 6e-23 Identities = 65/209 (31%), Positives = 124/209 (59%), Gaps = 22/209 (10%) Query: 5 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 64 E++++ K +R+E E + E K+Q Q E + EQ++++QEQEE + EQE + Sbjct: 298 EQLQDEAKHLRQEVEGL---EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRV 354 Query: 65 EQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123 ++E++ EQ +RL EQ++ + EQ ERLR++E+R+R+Q+ E+ + +EE++Q+Q Sbjct: 355 REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE---------ERLRKEEERLQKQ 405 Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKM-WEQEEKMREQ--------EEKMREQEEKMQGQEE 174 E+++ +QEE +W++EE++Q+QEE++ Q K+ +Q E+ E++ +Q +++ Sbjct: 406 EKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQ 465 Query: 175 KMRDVEPAGGEAGEGSPQDNPTAQEIMQL 203 E E E + Q N + + L Sbjct: 466 VKELQEKLDEEHLEAASQQNQQLETQLSL 494 Score = 101 bits (252), Expect = 5e-22 Identities = 56/209 (26%), Positives = 122/209 (58%), Gaps = 29/209 (13%) Query: 8 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67 +E++++++E+EEM+REQE + ++E++ EQ E++ EQ++ +QEQ E++ +QE+++ +QE Sbjct: 333 KEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE 392 Query: 68 EKM-WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEK 126 E++ E++RL +Q++++W+Q+ERL +KEER+++Q +E Q K Sbjct: 393 ERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQ---------------EERLALSQNHK 437 Query: 127 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE------ 180 + +Q E + +++ + E++++E +EK+ E+ + Q+ + + + Sbjct: 438 LDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQLSLVAL 497 Query: 181 PAGGEAG-------EGSPQDNPTAQEIMQ 202 P G+ G E +P+ P E ++ Sbjct: 498 PGEGDGGQHLDSEEEEAPRPTPNIPEDLE 526 Score = 97.8 bits (242), Expect = 7e-21 Identities = 59/196 (30%), Positives = 125/196 (63%), Gaps = 26/196 (13%) Query: 3 EEERMREREKKMREEEEMMREQEEK----MQEQEEKMREQEEKMWEQE-----------E 47 E R +ER KM E ++E++++ +QE E + E + +M + E Sbjct: 239 ERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVE 298 Query: 48 KMQEQEEKMWEQEEKMWEQEEKMWEQQRL-----PEQKEKMWEQDERLREKE-ERMREQ- 100 ++Q++ + + ++ E + + + E + EQK+++ EQ+E LRE+E +R+REQ Sbjct: 299 QLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQE 358 Query: 101 KMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160 ++ +Q E++RE++KT +QEQ E++++QE+ + +QEE+++++EE++ +QE+++ +QEE Sbjct: 359 RLCEQNERLREQQKT----LQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEE 414 Query: 161 KMREQEEKMQGQEEKM 176 ++ ++EE++Q QEE++ Sbjct: 415 RLWKKEERLQKQEERL 430 Score = 97.4 bits (241), Expect = 9e-21 Identities = 44/156 (28%), Positives = 107/156 (68%), Gaps = 6/156 (3%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 +EE +RE+E + E+E + EQ E+++EQ++ ++EQ E++ +QE+++++QEE++ ++EE+ Sbjct: 342 QEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEER 401 Query: 63 MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQE 122 + +QE+++W+Q+ E++W+++ERL+++EER+ + + +++ E + + E+ E Sbjct: 402 LQKQEKRLWDQE------ERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNE 455 Query: 123 QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 158 ++ +Q ++++ QE+ +E E +Q +++ Q Sbjct: 456 KKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQ 491 Score = 97.1 bits (240), Expect = 1e-20 Identities = 59/195 (30%), Positives = 120/195 (61%), Gaps = 21/195 (10%) Query: 2 REEERMREREKKMREEEEMMREQE-----------EKMQEQEEKMREQEE----KMWEQE 46 R+ R++E E+ + E + M + E++Q++ + +R++ E K+ Q Sbjct: 263 RDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQV 322 Query: 47 EKMQEQEEKMWEQEEKMWEQEEKMWEQ--QRLPEQKEKMWEQDERLREKEERMREQKMWQ 104 E Q EQ++++ EQEE + EQ QR+ EQ E++ EQ+ERLRE+++ ++EQ + Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQ-ERLCEQNERLREQQKTLQEQ--GE 379 Query: 105 QVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-EQEEKMR 163 ++ K ++ + QEE+++++EE++Q+QE+ +W+QEE++ ++EE++ +QEE++ Q K+ Sbjct: 380 RLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLD 439 Query: 164 EQEEKMQGQEEKMRD 178 +Q + Q E + + Sbjct: 440 KQLAEPQCSFEDLNN 454 Score = 60.5 bits (145), Expect = 1e-09 Identities = 66/305 (21%), Positives = 125/305 (40%), Gaps = 104/305 (34%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE--------------- 46 ++E+R+R++E+++R+EEE +++QE+++ +QEE++ ++EE++ +QE Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQL 442 Query: 47 -------EKMQEQEEKMWEQEEKMWEQEEKMWEQ-------------------------- 73 E + +++ + E+++ E +EK+ E+ Sbjct: 443 AEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQLSLVALPGEGD 502 Query: 74 --QRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEK------------ 108 Q L ++E+ + E E + +QVE+ Sbjct: 503 GGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQVERRELGFVQPSGVT 562 Query: 109 --MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM------REQEE 160 MRE E + + QE E+++ +K +E + K+ E +E + E Sbjct: 563 DGMRESFTVYESQGAVPNTRHQEMEDVI-RLAQKEEEMKVKLLELQELVLPLVGNHEGHG 621 Query: 161 KM----------------REQEEKMQGQEEKM------RDVEPAGGEAGEGSPQDNPTAQ 198 K QE G+++ +VEPA G A EGSP DNPT Q Sbjct: 622 KFLIAAQNPADEPTPGAPAPQELGAAGEQDDFYEVSLDNNVEPAPGAAREGSPHDNPTVQ 681 Query: 199 EIMQL 203 +I+QL Sbjct: 682 QIVQL 686 Score = 59.3 bits (142), Expect = 3e-09 Identities = 42/188 (22%), Positives = 92/188 (48%), Gaps = 2/188 (1%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE- 60 RE R ++ ++E + + + ++ E++E + + +E+MW+ Sbjct: 193 REAVLHRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSV 252 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 E +EEK + R+ E + + E ++ K + + VE+++++ K +++ Sbjct: 253 EARTLKEEKKRDIHRIQELERSLSELKNQMA-KPPSLAPPAVTSVVEQLQDEAKHLRQEV 311 Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 + E K+Q Q E +EQ++++ EQEE +REQE + ++E++ Q E++R+ + Sbjct: 312 EGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQ 371 Query: 181 PAGGEAGE 188 E GE Sbjct: 372 KTLQEQGE 379 Score = 30.8 bits (68), Expect = 1.1 Identities = 27/178 (15%), Positives = 78/178 (43%), Gaps = 2/178 (1%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63 E ++ E +K E + E+ E + + + + ++ + + EE+ + ++ Sbjct: 103 EHQLEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRL 162 Query: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123 +++ E +R ++++R E + +++ QQ K R ++ E Sbjct: 163 QYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLHRRL-QQTIKERALLNAHVTQVTES 221 Query: 124 EEKMQ-EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 +++Q E++E + + +E+MW+ + R +E+ + ++Q E + +++ Sbjct: 222 LKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELK 279 >gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sapiens] Length = 693 Score = 104 bits (259), Expect = 8e-23 Identities = 65/209 (31%), Positives = 124/209 (59%), Gaps = 22/209 (10%) Query: 5 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 64 E++++ K +R+E E + E K+Q Q E + EQ++++QEQEE + EQE + Sbjct: 298 EQLQDEAKHLRQEVEGL---EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRV 354 Query: 65 EQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123 ++E++ EQ +RL EQ++ + EQ ERLR++E+R+R+Q+ E+ + +EE++Q+Q Sbjct: 355 REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE---------ERLRKEEERLQKQ 405 Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKM-WEQEEKMREQ--------EEKMREQEEKMQGQEE 174 E+++ +QEE +W++EE++Q+QEE++ Q K+ +Q E+ E++ +Q +++ Sbjct: 406 EKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQ 465 Query: 175 KMRDVEPAGGEAGEGSPQDNPTAQEIMQL 203 E E E + Q N + + L Sbjct: 466 VKELQEKLDEEHLEAASQRNQQLETQLSL 494 Score = 101 bits (252), Expect = 5e-22 Identities = 59/204 (28%), Positives = 125/204 (61%), Gaps = 19/204 (9%) Query: 8 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67 +E++++++E+EEM+REQE + ++E++ EQ E++ EQ++ +QEQ E++ +QE+++ +QE Sbjct: 333 KEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE 392 Query: 68 EKM-WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEK 126 E++ E++RL +Q++++W+Q+ERL +KEER+++Q+ +Q K+ +Q + Sbjct: 393 ERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQE--------ERLALSQNHKLDKQLAE 444 Query: 127 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE-PAGGE 185 Q E + +++ + E+++ E +EK+ EE + ++ Q E ++ V P G+ Sbjct: 445 PQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASQRNQQLETQLSLVALPGEGD 502 Query: 186 AG-------EGSPQDNPTAQEIMQ 202 G E +P+ P E ++ Sbjct: 503 GGQHLDSEEEEAPRPTPNIPEDLE 526 Score = 99.4 bits (246), Expect = 2e-21 Identities = 60/196 (30%), Positives = 125/196 (63%), Gaps = 26/196 (13%) Query: 3 EEERMREREKKMREEEEMMREQEEK----MQEQEEKMREQEEKMWEQE-----------E 47 E R +ER KM E ++E++++ +QE E + E + +M E E Sbjct: 239 ERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVE 298 Query: 48 KMQEQEEKMWEQEEKMWEQEEKMWEQQRL-----PEQKEKMWEQDERLREKE-ERMREQ- 100 ++Q++ + + ++ E + + + E + EQK+++ EQ+E LRE+E +R+REQ Sbjct: 299 QLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQE 358 Query: 101 KMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160 ++ +Q E++RE++KT +QEQ E++++QE+ + +QEE+++++EE++ +QE+++ +QEE Sbjct: 359 RLCEQNERLREQQKT----LQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEE 414 Query: 161 KMREQEEKMQGQEEKM 176 ++ ++EE++Q QEE++ Sbjct: 415 RLWKKEERLQKQEERL 430 Score = 98.6 bits (244), Expect = 4e-21 Identities = 60/195 (30%), Positives = 120/195 (61%), Gaps = 21/195 (10%) Query: 2 REEERMREREKKMREEEEMMREQE-----------EKMQEQEEKMREQEE----KMWEQE 46 R+ R++E E+ + E + M E E++Q++ + +R++ E K+ Q Sbjct: 263 RDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQV 322 Query: 47 EKMQEQEEKMWEQEEKMWEQEEKMWEQ--QRLPEQKEKMWEQDERLREKEERMREQKMWQ 104 E Q EQ++++ EQEE + EQ QR+ EQ E++ EQ+ERLRE+++ ++EQ + Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQ-ERLCEQNERLREQQKTLQEQ--GE 379 Query: 105 QVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-EQEEKMR 163 ++ K ++ + QEE+++++EE++Q+QE+ +W+QEE++ ++EE++ +QEE++ Q K+ Sbjct: 380 RLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLD 439 Query: 164 EQEEKMQGQEEKMRD 178 +Q + Q E + + Sbjct: 440 KQLAEPQCSFEDLNN 454 Score = 97.8 bits (242), Expect = 7e-21 Identities = 44/157 (28%), Positives = 111/157 (70%), Gaps = 1/157 (0%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 +++R++E+E+ +RE+E ++E++ EQ E++REQ++ + EQ E++++QE+++ +QEE+ Sbjct: 335 QKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEER 394 Query: 63 MWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121 + ++EE++ +Q+ RL +Q+E++W+++ERL+++EER+ + + +++ E + + E+ Sbjct: 395 LRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNN 454 Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 158 E++ +Q ++++ QE+ +E E ++ +++ Q Sbjct: 455 EKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQ 491 Score = 94.4 bits (233), Expect = 8e-20 Identities = 59/212 (27%), Positives = 123/212 (58%), Gaps = 34/212 (16%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 +RE+ER+ E+ +++RE+++ ++EQ E++++QE+++R+QEE++ ++EE++Q+QE+++W+QE Sbjct: 354 VREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQE 413 Query: 61 EKMWEQEEKMWEQ-QRLP-EQKEKMWEQDERLREKE--------ERMREQKMWQQVEKMR 110 E++W++EE++ +Q +RL Q K+ D++L E + E+ ++ QQV++++ Sbjct: 414 ERLWKKEERLQKQEERLALSQNHKL---DKQLAEPQCSFEDLNNEKKSALQLEQQVKELQ 470 Query: 111 EKKKTQEEKMQEQEEKMQEQE---------------EMMWEQEEKMQEQEEKMWEQEEKM 155 E K EE ++ ++ Q+ E + + +EE+ + E E Sbjct: 471 E--KLDEEHLEAASQRNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESR 528 Query: 156 REQEEKMREQEEKMQGQEEKMRD----VEPAG 183 M +EK G E+ R V+P+G Sbjct: 529 EATSSFMDLPKEKADGTEQVERRELGFVQPSG 560 Score = 60.8 bits (146), Expect = 1e-09 Identities = 42/188 (22%), Positives = 92/188 (48%), Gaps = 2/188 (1%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE- 60 RE R ++ ++E + + + ++ E++E + + +E+MW+ Sbjct: 193 REAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSV 252 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 E +EEK + R+ E + + E ++ E + + VE+++++ K +++ Sbjct: 253 EARTLKEEKKRDIHRIQELERSLSELKNQMAEPPS-LAPPAVTSVVEQLQDEAKHLRQEV 311 Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 + E K+Q Q E +EQ++++ EQEE +REQE + ++E++ Q E++R+ + Sbjct: 312 EGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQ 371 Query: 181 PAGGEAGE 188 E GE Sbjct: 372 KTLQEQGE 379 Score = 57.8 bits (138), Expect = 8e-09 Identities = 65/305 (21%), Positives = 125/305 (40%), Gaps = 104/305 (34%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE--------------- 46 ++E+R+R++E+++R+EEE +++QE+++ +QEE++ ++EE++ +QE Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQL 442 Query: 47 -------EKMQEQEEKMWEQEEKMWEQEEKMWEQ-------------------------- 73 E + +++ + E+++ E +EK+ E+ Sbjct: 443 AEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSLVALPGEGD 502 Query: 74 --QRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEK------------ 108 Q L ++E+ + E E + +QVE+ Sbjct: 503 GGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQVERRELGFVQPSGVT 562 Query: 109 --MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM------REQEE 160 MRE E + + QE E+++ +K +E + K+ E +E + E Sbjct: 563 DGMRESFTVYESQGAVPNTRHQEMEDVI-RLAQKEEEMKVKLLELQELVLPLVGNHEGHG 621 Query: 161 KM----------------REQEEKMQGQEEKM------RDVEPAGGEAGEGSPQDNPTAQ 198 K QE G+++ +VEPA G A EGSP +NPT Q Sbjct: 622 KFLIAAQNPADEPTPGAPAPQELGAAGEQDVFYEVSLDNNVEPAPGVAREGSPHNNPTVQ 681 Query: 199 EIMQL 203 +I+QL Sbjct: 682 QIVQL 686 Score = 32.3 bits (72), Expect = 0.37 Identities = 32/200 (16%), Positives = 85/200 (42%), Gaps = 2/200 (1%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63 E ++ E +K E + EQ E + + + + ++ + + EE+ + ++ Sbjct: 103 EHQLEEAKKTNNEIHKAQMEQLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRL 162 Query: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123 + + E +R ++++R E + ++++ QQ K R ++ E Sbjct: 163 QYSLQHIQELERALCAVSTQQQEEDRSSSCREAVLQRRL-QQTIKERALLNAHVTQVTES 221 Query: 124 EEKMQ-EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPA 182 +++Q E++E + + +E+MW+ + R +E+ + ++Q E + +++ Sbjct: 222 LKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQ 281 Query: 183 GGEAGEGSPQDNPTAQEIMQ 202 E +P + E +Q Sbjct: 282 MAEPPSLAPPAVTSVVEQLQ 301 >gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C isoform 1 [Homo sapiens] Length = 693 Score = 104 bits (259), Expect = 8e-23 Identities = 65/209 (31%), Positives = 124/209 (59%), Gaps = 22/209 (10%) Query: 5 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 64 E++++ K +R+E E + E K+Q Q E + EQ++++QEQEE + EQE + Sbjct: 298 EQLQDEAKHLRQEVEGL---EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRV 354 Query: 65 EQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123 ++E++ EQ +RL EQ++ + EQ ERLR++E+R+R+Q+ E+ + +EE++Q+Q Sbjct: 355 REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE---------ERLRKEEERLQKQ 405 Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKM-WEQEEKMREQ--------EEKMREQEEKMQGQEE 174 E+++ +QEE +W++EE++Q+QEE++ Q K+ +Q E+ E++ +Q +++ Sbjct: 406 EKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQ 465 Query: 175 KMRDVEPAGGEAGEGSPQDNPTAQEIMQL 203 E E E + Q N + + L Sbjct: 466 VKELQEKLDEEHLEAASQRNQQLETQLSL 494 Score = 101 bits (252), Expect = 5e-22 Identities = 59/204 (28%), Positives = 125/204 (61%), Gaps = 19/204 (9%) Query: 8 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67 +E++++++E+EEM+REQE + ++E++ EQ E++ EQ++ +QEQ E++ +QE+++ +QE Sbjct: 333 KEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE 392 Query: 68 EKM-WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEK 126 E++ E++RL +Q++++W+Q+ERL +KEER+++Q+ +Q K+ +Q + Sbjct: 393 ERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQE--------ERLALSQNHKLDKQLAE 444 Query: 127 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE-PAGGE 185 Q E + +++ + E+++ E +EK+ EE + ++ Q E ++ V P G+ Sbjct: 445 PQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASQRNQQLETQLSLVALPGEGD 502 Query: 186 AG-------EGSPQDNPTAQEIMQ 202 G E +P+ P E ++ Sbjct: 503 GGQHLDSEEEEAPRPTPNIPEDLE 526 Score = 99.4 bits (246), Expect = 2e-21 Identities = 60/196 (30%), Positives = 125/196 (63%), Gaps = 26/196 (13%) Query: 3 EEERMREREKKMREEEEMMREQEEK----MQEQEEKMREQEEKMWEQE-----------E 47 E R +ER KM E ++E++++ +QE E + E + +M E E Sbjct: 239 ERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVE 298 Query: 48 KMQEQEEKMWEQEEKMWEQEEKMWEQQRL-----PEQKEKMWEQDERLREKE-ERMREQ- 100 ++Q++ + + ++ E + + + E + EQK+++ EQ+E LRE+E +R+REQ Sbjct: 299 QLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQE 358 Query: 101 KMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160 ++ +Q E++RE++KT +QEQ E++++QE+ + +QEE+++++EE++ +QE+++ +QEE Sbjct: 359 RLCEQNERLREQQKT----LQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEE 414 Query: 161 KMREQEEKMQGQEEKM 176 ++ ++EE++Q QEE++ Sbjct: 415 RLWKKEERLQKQEERL 430 Score = 98.6 bits (244), Expect = 4e-21 Identities = 60/195 (30%), Positives = 120/195 (61%), Gaps = 21/195 (10%) Query: 2 REEERMREREKKMREEEEMMREQE-----------EKMQEQEEKMREQEE----KMWEQE 46 R+ R++E E+ + E + M E E++Q++ + +R++ E K+ Q Sbjct: 263 RDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQV 322 Query: 47 EKMQEQEEKMWEQEEKMWEQEEKMWEQ--QRLPEQKEKMWEQDERLREKEERMREQKMWQ 104 E Q EQ++++ EQEE + EQ QR+ EQ E++ EQ+ERLRE+++ ++EQ + Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQ-ERLCEQNERLREQQKTLQEQ--GE 379 Query: 105 QVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-EQEEKMR 163 ++ K ++ + QEE+++++EE++Q+QE+ +W+QEE++ ++EE++ +QEE++ Q K+ Sbjct: 380 RLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLD 439 Query: 164 EQEEKMQGQEEKMRD 178 +Q + Q E + + Sbjct: 440 KQLAEPQCSFEDLNN 454 Score = 97.8 bits (242), Expect = 7e-21 Identities = 44/157 (28%), Positives = 111/157 (70%), Gaps = 1/157 (0%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 +++R++E+E+ +RE+E ++E++ EQ E++REQ++ + EQ E++++QE+++ +QEE+ Sbjct: 335 QKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEER 394 Query: 63 MWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121 + ++EE++ +Q+ RL +Q+E++W+++ERL+++EER+ + + +++ E + + E+ Sbjct: 395 LRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNN 454 Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 158 E++ +Q ++++ QE+ +E E ++ +++ Q Sbjct: 455 EKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQ 491 Score = 94.4 bits (233), Expect = 8e-20 Identities = 59/212 (27%), Positives = 123/212 (58%), Gaps = 34/212 (16%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 +RE+ER+ E+ +++RE+++ ++EQ E++++QE+++R+QEE++ ++EE++Q+QE+++W+QE Sbjct: 354 VREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQE 413 Query: 61 EKMWEQEEKMWEQ-QRLP-EQKEKMWEQDERLREKE--------ERMREQKMWQQVEKMR 110 E++W++EE++ +Q +RL Q K+ D++L E + E+ ++ QQV++++ Sbjct: 414 ERLWKKEERLQKQEERLALSQNHKL---DKQLAEPQCSFEDLNNEKKSALQLEQQVKELQ 470 Query: 111 EKKKTQEEKMQEQEEKMQEQE---------------EMMWEQEEKMQEQEEKMWEQEEKM 155 E K EE ++ ++ Q+ E + + +EE+ + E E Sbjct: 471 E--KLDEEHLEAASQRNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESR 528 Query: 156 REQEEKMREQEEKMQGQEEKMRD----VEPAG 183 M +EK G E+ R V+P+G Sbjct: 529 EATSSFMDLPKEKADGTEQVERRELGFVQPSG 560 Score = 60.8 bits (146), Expect = 1e-09 Identities = 42/188 (22%), Positives = 92/188 (48%), Gaps = 2/188 (1%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE- 60 RE R ++ ++E + + + ++ E++E + + +E+MW+ Sbjct: 193 REAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSV 252 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 E +EEK + R+ E + + E ++ E + + VE+++++ K +++ Sbjct: 253 EARTLKEEKKRDIHRIQELERSLSELKNQMAEPPS-LAPPAVTSVVEQLQDEAKHLRQEV 311 Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 + E K+Q Q E +EQ++++ EQEE +REQE + ++E++ Q E++R+ + Sbjct: 312 EGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQ 371 Query: 181 PAGGEAGE 188 E GE Sbjct: 372 KTLQEQGE 379 Score = 58.2 bits (139), Expect = 6e-09 Identities = 65/305 (21%), Positives = 124/305 (40%), Gaps = 104/305 (34%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE--------------- 46 ++E+R+R++E+++R+EEE +++QE+++ +QEE++ ++EE++ +QE Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQL 442 Query: 47 -------EKMQEQEEKMWEQEEKMWEQEEKMWEQ-------------------------- 73 E + +++ + E+++ E +EK+ E+ Sbjct: 443 AEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSLVALPGEGD 502 Query: 74 --QRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEK------------ 108 Q L ++E+ + E E + +QVE+ Sbjct: 503 GGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQVERRELGFVQPSGVT 562 Query: 109 --MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM------REQEE 160 MRE E + + QE E+++ +K +E + K+ E +E + E Sbjct: 563 DGMRESFTVYESQGAVPNTRHQEMEDVI-RLAQKEEEMKVKLLELQELVLPLVGNHEGHG 621 Query: 161 KM----------------REQEEKMQGQEEKM------RDVEPAGGEAGEGSPQDNPTAQ 198 K QE G+++ +VEPA G A EGSP DNP Q Sbjct: 622 KFLIAAQNPADEPTPGAPAPQELGAAGEQDDFYEVSLDNNVEPAPGAAREGSPHDNPPVQ 681 Query: 199 EIMQL 203 +I+QL Sbjct: 682 QIVQL 686 Score = 35.0 bits (79), Expect = 0.057 Identities = 32/200 (16%), Positives = 86/200 (43%), Gaps = 2/200 (1%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63 E ++ E +K E + EQ E + + + + ++ + + EE+ + ++ Sbjct: 103 EHQLEEAKKTNNEIHKAQMEQLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRL 162 Query: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123 +++ E +R ++++R E + ++++ QQ K R ++ E Sbjct: 163 QYSLQRIQELERALSAVSTQQQEEDRSSSCREAVLQRRL-QQTIKERALLNAHVTQVTES 221 Query: 124 EEKMQ-EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPA 182 +++Q E++E + + +E+MW+ + R +E+ + ++Q E + +++ Sbjct: 222 LKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQ 281 Query: 183 GGEAGEGSPQDNPTAQEIMQ 202 E +P + E +Q Sbjct: 282 MAEPPSLAPPAVTSVVEQLQ 301 >gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapiens] Length = 693 Score = 103 bits (257), Expect = 1e-22 Identities = 58/178 (32%), Positives = 114/178 (64%), Gaps = 14/178 (7%) Query: 5 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 64 E++++ K +R+E E + E K+Q Q E + EQ++++QEQEE + EQE + Sbjct: 298 EQLQDEAKHLRQEVEGL---EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRV 354 Query: 65 EQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123 ++E++ EQ +RL EQ++ + EQ ERLR++E+R+R+Q+ E+ + +EE++Q+Q Sbjct: 355 REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE---------ERLRKEEERLQKQ 405 Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKM-WEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 E+++ +QEE +W++EE++Q+QEE++ Q K+ +Q + + E + +++ +E Sbjct: 406 EKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLE 463 Score = 100 bits (250), Expect = 8e-22 Identities = 58/204 (28%), Positives = 125/204 (61%), Gaps = 19/204 (9%) Query: 8 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67 +E++++++E+EEM+REQE + ++E++ EQ E++ EQ++ +QEQ E++ +QE+++ +QE Sbjct: 333 KEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE 392 Query: 68 EKM-WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEK 126 E++ E++RL +Q++++W+Q+ERL +KEER+++Q+ +Q K+ +Q + Sbjct: 393 ERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQE--------ERLALSQNHKLDKQLAE 444 Query: 127 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE-EKMREQEEKMQGQEEKMRDVEPAGGE 185 Q E + +++ + E+++ E +EK+ E+ E Q ++++ Q + P G+ Sbjct: 445 PQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASHQNQQLETQLSLV--ALPGEGD 502 Query: 186 AG-------EGSPQDNPTAQEIMQ 202 G E +P+ P E ++ Sbjct: 503 GGQHLDSEEEEAPRPTPNIPEDLE 526 Score = 99.4 bits (246), Expect = 2e-21 Identities = 60/196 (30%), Positives = 125/196 (63%), Gaps = 26/196 (13%) Query: 3 EEERMREREKKMREEEEMMREQEEK----MQEQEEKMREQEEKMWEQE-----------E 47 E R +ER KM E ++E++++ +QE E + E + +M E E Sbjct: 239 ERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVE 298 Query: 48 KMQEQEEKMWEQEEKMWEQEEKMWEQQRL-----PEQKEKMWEQDERLREKE-ERMREQ- 100 ++Q++ + + ++ E + + + E + EQK+++ EQ+E LRE+E +R+REQ Sbjct: 299 QLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQE 358 Query: 101 KMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160 ++ +Q E++RE++KT +QEQ E++++QE+ + +QEE+++++EE++ +QE+++ +QEE Sbjct: 359 RLCEQNERLREQQKT----LQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEE 414 Query: 161 KMREQEEKMQGQEEKM 176 ++ ++EE++Q QEE++ Sbjct: 415 RLWKKEERLQKQEERL 430 Score = 98.6 bits (244), Expect = 4e-21 Identities = 60/195 (30%), Positives = 120/195 (61%), Gaps = 21/195 (10%) Query: 2 REEERMREREKKMREEEEMMREQE-----------EKMQEQEEKMREQEE----KMWEQE 46 R+ R++E E+ + E + M E E++Q++ + +R++ E K+ Q Sbjct: 263 RDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQV 322 Query: 47 EKMQEQEEKMWEQEEKMWEQEEKMWEQ--QRLPEQKEKMWEQDERLREKEERMREQKMWQ 104 E Q EQ++++ EQEE + EQ QR+ EQ E++ EQ+ERLRE+++ ++EQ + Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQ-ERLCEQNERLREQQKTLQEQ--GE 379 Query: 105 QVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-EQEEKMR 163 ++ K ++ + QEE+++++EE++Q+QE+ +W+QEE++ ++EE++ +QEE++ Q K+ Sbjct: 380 RLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLD 439 Query: 164 EQEEKMQGQEEKMRD 178 +Q + Q E + + Sbjct: 440 KQLAEPQCSFEDLNN 454 Score = 98.6 bits (244), Expect = 4e-21 Identities = 45/157 (28%), Positives = 110/157 (70%), Gaps = 1/157 (0%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 +++R++E+E+ +RE+E ++E++ EQ E++REQ++ + EQ E++++QE+++ +QEE+ Sbjct: 335 QKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEER 394 Query: 63 MWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121 + ++EE++ +Q+ RL +Q+E++W+++ERL+++EER+ + + +++ E + + E+ Sbjct: 395 LRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNN 454 Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 158 E++ +Q ++++ QE+ +E E Q +++ Q Sbjct: 455 EKKSALQLEQQVKELQEKLDEEHLEAASHQNQQLETQ 491 Score = 93.6 bits (231), Expect = 1e-19 Identities = 58/210 (27%), Positives = 122/210 (58%), Gaps = 30/210 (14%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 +RE+ER+ E+ +++RE+++ ++EQ E++++QE+++R+QEE++ ++EE++Q+QE+++W+QE Sbjct: 354 VREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQE 413 Query: 61 EKMWEQEEKMWEQ-QRLP-EQKEKMWEQDERLREKE--------ERMREQKMWQQVEKMR 110 E++W++EE++ +Q +RL Q K+ D++L E + E+ ++ QQV++++ Sbjct: 414 ERLWKKEERLQKQEERLALSQNHKL---DKQLAEPQCSFEDLNNEKKSALQLEQQVKELQ 470 Query: 111 EKKKTQE-EKMQEQEEKMQEQEEM------------MWEQEEKMQEQEEKMWEQEEKMRE 157 EK + E Q ++++ Q + + +EE+ + E E Sbjct: 471 EKLDEEHLEAASHQNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREA 530 Query: 158 QEEKMREQEEKMQGQEEKMRD----VEPAG 183 M +EK G E+ R V+P+G Sbjct: 531 TSSFMDLPKEKADGTEQVERRELGFVQPSG 560 Score = 60.1 bits (144), Expect = 2e-09 Identities = 66/305 (21%), Positives = 125/305 (40%), Gaps = 104/305 (34%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE--------------- 46 ++E+R+R++E+++R+EEE +++QE+++ +QEE++ ++EE++ +QE Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQL 442 Query: 47 -------EKMQEQEEKMWEQEEKMWEQEEKMWEQ-------------------------- 73 E + +++ + E+++ E +EK+ E+ Sbjct: 443 AEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASHQNQQLETQLSLVALPGEGD 502 Query: 74 --QRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEK------------ 108 Q L ++E+ + E E + +QVE+ Sbjct: 503 GGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQVERRELGFVQPSGVT 562 Query: 109 --MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM------REQEE 160 MRE E + + QE E+++ +K +E + K+ E +E + E Sbjct: 563 DGMRESFTVYESQGAVPNTRHQEMEDVI-RLAQKEEEMKVKLLELQELVLPLVGNHEGHG 621 Query: 161 KM----------------REQEEKMQGQEEKM------RDVEPAGGEAGEGSPQDNPTAQ 198 K QE G+++ +VEPA G A EGSP DNPT Q Sbjct: 622 KFLIAAQNPADEPTPGAPAPQELGAAGEQDVFYEVSLDNNVEPAPGAAREGSPHDNPTVQ 681 Query: 199 EIMQL 203 +I+QL Sbjct: 682 QIVQL 686 Score = 59.7 bits (143), Expect = 2e-09 Identities = 42/188 (22%), Positives = 92/188 (48%), Gaps = 2/188 (1%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE- 60 RE R ++ ++E + + + ++ E++E + + +E+MW+ Sbjct: 193 REAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSV 252 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 E +EEK + R+ E + + E ++ E + + VE+++++ K +++ Sbjct: 253 EARTLKEEKKRDIHRIQELERSLSELKNQMAEPPS-LAPPAVTSVVEQLQDEAKHLRQEV 311 Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 + E K+Q Q E +EQ++++ EQEE +REQE + ++E++ Q E++R+ + Sbjct: 312 EGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQ 371 Query: 181 PAGGEAGE 188 E GE Sbjct: 372 KTLQEQGE 379 Score = 31.2 bits (69), Expect = 0.82 Identities = 38/215 (17%), Positives = 93/215 (43%), Gaps = 25/215 (11%) Query: 13 KMREEEEMMREQEEKMQEQEEKMREQEEKMWE-QEEKMQEQEEKMWEQEE---------- 61 ++ E E +++Q+++++ Q E+ ++ ++ + Q E+++ E+ + Sbjct: 87 QLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKR 146 Query: 62 --KMWEQEEK------MWEQQRLPEQKEKMW----EQDERLREKEERMREQKMW-QQVEK 108 + +E+E K + QR+ E + + +Q E R R + W QQ K Sbjct: 147 AARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLQRWLQQTIK 206 Query: 109 MREKKKTQEEKMQEQEEKMQ-EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167 R ++ E +++Q E++E + + +E+MW+ + R +E+ + Sbjct: 207 ERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIH 266 Query: 168 KMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEIMQ 202 ++Q E + +++ E +P + E +Q Sbjct: 267 RIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQ 301 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 99.8 bits (247), Expect = 2e-21 Identities = 54/181 (29%), Positives = 117/181 (64%), Gaps = 2/181 (1%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE-QEEKMQEQEEKMWEQ 59 +RE ER E K+ ++E E R++E + +E+ ++ RE+E K ++EK E++++ E+ Sbjct: 38 IREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERER 97 Query: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119 +++ E+E K E++ ++KEK E+ +E +ER R+++ ++ K RE+KK + EK Sbjct: 98 KKRRREKENKEGEEKEKRKKKEKK-ERGRTSKEGKERERKEERKREERKERERKKEEREK 156 Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDV 179 +E++E+ + + + + E+EE+ +E+E K ++ E+ R++ +K RE++E+ + ++E+ + Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216 Query: 180 E 180 E Sbjct: 217 E 217 Score = 95.1 bits (235), Expect = 5e-20 Identities = 52/174 (29%), Positives = 114/174 (65%), Gaps = 6/174 (3%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 RE+ER RER KK ++ E R++EE+ E++++ RE+E K E++EK +++E+K + Sbjct: 73 REKERKRERGKKEKKGE---RKKEER--ERKKRRREKENKEGEEKEKRKKKEKKERGRTS 127 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121 K ++ E+ E++R E+KE+ +++ER +E+E + R+++ +QV + E++K +E K + Sbjct: 128 KEGKERERKEERKR-EERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186 Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175 ++ E+ +++ + E++E+ + ++E+ ++E K Q+++ EK +G+ E+ Sbjct: 187 KKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRER 240 Score = 85.9 bits (211), Expect = 3e-17 Identities = 48/167 (28%), Positives = 102/167 (61%), Gaps = 7/167 (4%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM-QEQEEKMWEQEE 61 ++E+ ER+K+ RE ++ RE+E K E++EK +++E+K + K +E+E K + E Sbjct: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121 + E+E K E+++ E+KE+ + +++ EKEE +E+ E+ KK+ + K + Sbjct: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEK------ERKERKKRERNRKER 196 Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168 ++E + +E+ E E+++K + ++E+ +++ RE+E RE++E+ Sbjct: 197 KKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243 Score = 63.9 bits (154), Expect = 1e-10 Identities = 37/146 (25%), Positives = 84/146 (57%), Gaps = 2/146 (1%) Query: 43 WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKM 102 W+ E + +E+E + ++ +K E E K ++R ++E+ E+ +KE++ +K Sbjct: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93 Query: 103 WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 162 ++ +K R +K+ +E + +E+ +K +++E +E K +E++E+ +E K RE++++ Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153 Query: 163 REQEEKMQGQEEKMRDVEPAGGEAGE 188 RE+E + +E K R+ + G + E Sbjct: 154 REKER--ERKERKKRERKQVGEKEEE 177 Score = 49.3 bits (116), Expect = 3e-06 Identities = 29/111 (26%), Positives = 64/111 (57%), Gaps = 11/111 (9%) Query: 84 WEQDERLREKE-ERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQ 142 W+ + R RE+E E +E K ++ E+ +E+++ ++ K + ++E+ +E+ + K + Sbjct: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK-------KEK 86 Query: 143 EQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQD 193 + E K E+E K R +E++ +E EEK ++ K ++ + G + EG ++ Sbjct: 87 KGERKKEERERKKRRREKENKEGEEK---EKRKKKEKKERGRTSKEGKERE 134 Score = 41.6 bits (96), Expect = 6e-04 Identities = 24/89 (26%), Positives = 55/89 (61%), Gaps = 8/89 (8%) Query: 100 QKMWQQVEKMRE-----KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ---EEKMWEQ 151 Q WQ + RE +K+ ++E+ E++++ +E+E+ E+E++ + + +EK E+ Sbjct: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90 Query: 152 EEKMREQEEKMREQEEKMQGQEEKMRDVE 180 +++ RE++++ RE+E K ++EK + E Sbjct: 91 KKEERERKKRRREKENKEGEEKEKRKKKE 119 Score = 31.6 bits (70), Expect = 0.63 Identities = 21/70 (30%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Query: 112 KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE-EKMREQEEKMQ 170 K TQ E E+ +E E ++E+ E++++ E+E++ RE+E E+ RE+ +K + Sbjct: 27 KPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEK 86 Query: 171 GQEEKMRDVE 180 E K + E Sbjct: 87 KGERKKEERE 96 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 98.6 bits (244), Expect = 4e-21 Identities = 52/186 (27%), Positives = 118/186 (63%), Gaps = 8/186 (4%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 +EE ++ + E+K+ +EE + ++E K+ + K+ + + +M + E K ++EE + ++ E Sbjct: 1590 QEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGE 1649 Query: 62 KMWEQEEKMWEQQR-LPEQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKT--- 115 K+ ++ EK+ ++++ L ++ EK+ ++E+L +K ++ E K + Q+VE++ ++++ Sbjct: 1650 KLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDW 1709 Query: 116 -QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 174 ++E QE EE + EE+ W++EE + ++E K+ E+++K+ E+EE + Q EK+ +E Sbjct: 1710 QEKELAQELEELEWDMEELSWKEEE-LNQEEGKLVEEKKKLAEEEEALAWQREKLSEEET 1768 Query: 175 KMRDVE 180 K+ E Sbjct: 1769 KLAQEE 1774 Score = 97.8 bits (242), Expect = 7e-21 Identities = 47/180 (26%), Positives = 120/180 (66%), Gaps = 6/180 (3%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 ++EE + +R +K+ +E E + ++ +K+ ++ EK+ +EEK+ ++ K+ E + + ++ E Sbjct: 1639 QKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVE 1698 Query: 62 KMWEQEEKM-WEQQRLPEQKEKM-WEQDE-RLREKEERMREQKMWQQVEKMREKKKT--- 115 ++ ++E+ + W+++ L ++ E++ W+ +E +E+E E K+ ++ +K+ E+++ Sbjct: 1699 ELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAW 1758 Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175 Q EK+ E+E K+ ++EE++ +++EK+ + +EKM E+EE++ + E++ E++ K+ + E+ Sbjct: 1759 QREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRER 1818 Score = 96.7 bits (239), Expect = 2e-20 Identities = 52/193 (26%), Positives = 122/193 (63%), Gaps = 6/193 (3%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 +EE ++ + K+ +++ M + E K ++EE + ++ EK+ ++ EK+ ++ +K+ ++ E Sbjct: 1611 QEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWE 1670 Query: 62 KMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERM--REQKMWQQVEKMR---EKKKT 115 K+ +EEK+ ++ +L E K + ++ E L ++E+ + +E+++ Q++E++ E+ Sbjct: 1671 KVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSW 1730 Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175 +EE++ ++E K+ E+++ + E+EE + Q EK+ E+E K+ ++EE + +++EK+ +EK Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEK 1790 Query: 176 MRDVEPAGGEAGE 188 M + E G E Sbjct: 1791 MPEEEERLGRKRE 1803 Score = 94.0 bits (232), Expect = 1e-19 Identities = 52/202 (25%), Positives = 118/202 (58%), Gaps = 15/202 (7%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 +EE ++ E +KK+ EEEE + Q EK+ E+E K+ ++EE + +++EK+ + +EKM E+EE Sbjct: 1737 QEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEE 1796 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT---QEE 118 ++ + E++ E++ QK + W + EE + + + Q + + ++KK ++E Sbjct: 1797 RLGRKREQLIEKKMKLAQKRERW-----INSMEELTKNKMILYQKKNLAQEKKNLAQEKE 1851 Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMW-------EQEEKMREQEEKMREQEEKMQG 171 K+ +++E + +E + ++++ + + K+ + EEK+ +++E + +++EK+ Sbjct: 1852 KLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAE 1911 Query: 172 QEEKMRDVEPAGGEAGEGSPQD 193 E+K+ VE + + E Q+ Sbjct: 1912 TEKKLVQVEDSLAKKQEKLAQE 1933 Score = 92.4 bits (228), Expect = 3e-19 Identities = 54/184 (29%), Positives = 108/184 (58%), Gaps = 16/184 (8%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 REEE++ ++ K+ E + ++ ++ E++ ++E+ + W+++E QE EE W+ EE Sbjct: 1674 REEEKLAKKGGKLAEVKNILAQKVEELPQREQNLD------WQEKELAQELEELEWDMEE 1727 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKM---REKKKTQ 116 W++EE E+ +L E+K+K+ E++E L + E++ E+ K+ Q+ E + +EK Sbjct: 1728 LSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQH 1787 Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEE-----KMREQEEKMREQEEKMQG 171 +EKM E+EE++ + E + E++ K+ ++ E+ E KM ++K QE+K Sbjct: 1788 KEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLA 1847 Query: 172 QEEK 175 QE++ Sbjct: 1848 QEKE 1851 Score = 91.7 bits (226), Expect = 5e-19 Identities = 59/196 (30%), Positives = 111/196 (56%), Gaps = 23/196 (11%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM--------WEQEEKMQEQ 52 +++E ++ + +++M +EE M E+ E+M EEK+ +QE K+ W+ +K ++ Sbjct: 1407 VQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDE 1466 Query: 53 EEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKM-----WQQVE 107 +++ + K W+ ++ WE +RL +++EK+ + E+L +EE ++E K W+QV Sbjct: 1467 WKQVHGETRKSWKAWKEEWE-KRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVW 1525 Query: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQE--------QEEKMWEQEEKMREQE 159 + K++E++ +++EE E EE+ E EEK Q+ QEE W + + R + Sbjct: 1526 ENMLSSKSKEQQYKDEEEVTLE-EEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARA 1584 Query: 160 EKMREQEEKMQGQEEK 175 EK R QEE+ QEE+ Sbjct: 1585 EKKRAQEERKLAQEEE 1600 Score = 90.5 bits (223), Expect = 1e-18 Identities = 54/192 (28%), Positives = 112/192 (58%), Gaps = 20/192 (10%) Query: 6 RMRER-EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 64 R R R EKK +EE + ++EEK+ ++E ++ ++E K+ + K+ + + +M + E K Sbjct: 1579 RKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFA 1638 Query: 65 EQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERM--REQKMWQQVEKMREKKKTQEEKMQ 121 ++EE + ++ ++L ++ EK+ ++ ++L +K E++ E+K+ ++ K+ E K +K+ Sbjct: 1639 QKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKV- 1697 Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEE-------------KMREQEEKMREQEEK 168 EE Q ++ + W+++E QE EE W+ EE K+ E+++K+ E+EE Sbjct: 1698 --EELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEA 1755 Query: 169 MQGQEEKMRDVE 180 + Q EK+ + E Sbjct: 1756 LAWQREKLSEEE 1767 Score = 90.1 bits (222), Expect = 1e-18 Identities = 46/172 (26%), Positives = 103/172 (59%), Gaps = 8/172 (4%) Query: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 68 E EK++ +EEE + + EK+ +EE ++E ++ WE+ +++ E +E++ ++EE Sbjct: 1484 EWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEE 1543 Query: 69 KMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR---EKKKTQEE-KMQEQE 124 E++ E +EK ++++ E++ ++E+ W ++ + R EKK+ QEE K+ ++E Sbjct: 1544 VTLEEEVSREGEEK----EQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEE 1599 Query: 125 EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 EK+ ++E + ++E K+ + K+ + + +M + E K ++EE + + EK+ Sbjct: 1600 EKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKL 1651 Score = 86.3 bits (212), Expect = 2e-17 Identities = 59/229 (25%), Positives = 123/229 (53%), Gaps = 54/229 (23%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 + E+ + +EK++ +E E + E++ +EE++ ++E K+ E+++K+ E+EE + Q E Sbjct: 1702 QREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQRE 1761 Query: 62 KMWEQEEKM--------WEQQRLPEQKEKMWEQDERLREKEERMREQKM--------W-- 103 K+ E+E K+ E+++L + KEKM E++ERL K E++ E+KM W Sbjct: 1762 KLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWIN 1821 Query: 104 --QQVEK----MREKKKTQEEK---MQEQEEKMQEQEEMMWEQ----------------- 137 +++ K + +KK +EK QE+E+ Q +E +++ + Sbjct: 1822 SMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKL 1881 Query: 138 ----------EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 EEK+ +++E + +++EK+ E E+K+ + E+ + ++EK+ Sbjct: 1882 GMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKL 1930 Score = 85.1 bits (209), Expect = 5e-17 Identities = 60/208 (28%), Positives = 114/208 (54%), Gaps = 36/208 (17%) Query: 1 MREEERMREREKKM-REEEEMMREQEEKMQEQEEKMREQEEKMW---------------- 43 + +EE+M E E K+ R+ E++ + EE+ +EE++ ++ W Sbjct: 2154 INKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKF 2213 Query: 44 -------EQEEKMQEQEEKMWEQEEKM-----WEQEEKMWEQQRLPEQKEKMWEQDERLR 91 E EE E+ E + ++ EK E+EE+ E++R ++E++ E++E + Sbjct: 2214 SSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEER---EEEEVREEEEERK 2270 Query: 92 EKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKM----QEQEEK 147 E+EE +Q ++ EK ++KK+ ++E++QE+EE +E+EE+M E+E + +E+EE Sbjct: 2271 EEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEES 2330 Query: 148 MWEQEEKMREQEEKMREQEEKMQGQEEK 175 +EE RE+E +E++ K+Q Q K Sbjct: 2331 CSLEEEVDREKEILKKEKQFKLQEQRRK 2358 Score = 83.2 bits (204), Expect = 2e-16 Identities = 56/205 (27%), Positives = 115/205 (56%), Gaps = 8/205 (3%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKM-REQEEKMWEQEEKMQEQEEKMWEQE 60 ++E+++ +++K+ + M +EEKM E+E K+ R+ E + + EE+ +EE++ Sbjct: 2134 KDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFL 2193 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 ++ W + + E +R + KEK Q + + +E E + + +E ++EE+ Sbjct: 2194 KRRWRKRK---EAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEE 2250 Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQ--EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178 +E+EE+ +E+EE+ E+EE+ +E+ EEK E+EE+ +++++K +++EE +Q +EE + Sbjct: 2251 REEEEE-REEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEE-VQEKEEVFEE 2308 Query: 179 VEPAGGEAGEGSPQDNPTAQEIMQL 203 E E S D +E L Sbjct: 2309 KEEIMSEEETESLSDEEEEEESCSL 2333 Score = 80.9 bits (198), Expect = 9e-16 Identities = 44/193 (22%), Positives = 116/193 (60%), Gaps = 10/193 (5%) Query: 1 MREEERMREREKKMR-EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 + EEE +E+++ +E+E + + +EKM E+EE++ + E++ E++ K+ ++ E+ Sbjct: 1763 LSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINS 1822 Query: 60 EEK-------MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREK 112 E+ +++++ E++ L ++KEK+ ++ E L +ER+ K +Q+ +++ K Sbjct: 1823 MEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSK--KQLVQVKNK 1880 Query: 113 KKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 172 + + + EEK+ +++E + +++EK+ E E+K+ + E+ + +++EK+ +++ K+ + Sbjct: 1881 LGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALE 1940 Query: 173 EEKMRDVEPAGGE 185 + ++ + GE Sbjct: 1941 KAMVQGKKRLRGE 1953 Score = 80.5 bits (197), Expect = 1e-15 Identities = 48/194 (24%), Positives = 112/194 (57%), Gaps = 23/194 (11%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 +EE +M + ++ + +E + ++ K+ +E E+ ++ + E+K+ ++ K+ + Sbjct: 2092 QEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMR 2151 Query: 62 KMWEQEEKMWEQQR----------LPEQKEKMWEQDERLREKEERMREQKMWQQVEKMRE 111 +M +EEKM E++ L +++E E++E + + R R++K ++ +K +E Sbjct: 2152 RMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKE 2211 Query: 112 KKKTQEEKMQEQE----------EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK 161 K +Q ++++ +E +++++QE + E+EE+ +E+EE+ +EE++RE+EE+ Sbjct: 2212 KFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEER---EEEEVREEEEE 2268 Query: 162 MREQEEKMQGQEEK 175 +E+EE + Q EK Sbjct: 2269 RKEEEEGEEKQVEK 2282 Score = 76.3 bits (186), Expect = 2e-14 Identities = 52/188 (27%), Positives = 99/188 (52%), Gaps = 14/188 (7%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63 +E ++ EKK ++ +Q K ++E K+ + + +M ++E M E+ E+M EEK+ Sbjct: 1385 KEISKKEEKKTFQKSP---KQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKV 1441 Query: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR-----EKKKTQEE 118 +QE K+ +R P ++ DE + E + K W++ + R EK E Sbjct: 1442 VKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGE 1501 Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQE------QEEKMWEQEEKMREQEEKMREQEEKMQGQ 172 K+ +EE +QE +++ WE+ +++ E +E+ ++ EE++ +EE RE EEK Q Sbjct: 1502 KLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQV 1561 Query: 173 EEKMRDVE 180 E+ R ++ Sbjct: 1562 TEEQRHIQ 1569 Score = 75.9 bits (185), Expect = 3e-14 Identities = 50/153 (32%), Positives = 93/153 (60%), Gaps = 13/153 (8%) Query: 9 EREKKMREEEEMMREQEEKMQ----EQEEKMREQEEKMWEQEEKMQEQEEKMWEQ--EEK 62 E E+ EE E + ++ EK + E+EE+ E+EE+ E+EE +E+EE+ E+ EEK Sbjct: 2221 ESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEER--EEEEVREEEEERKEEEEGEEK 2278 Query: 63 MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQE 122 E+EE+ ++++ ++KE++ E++E EKEE M E ++ E + ++++ +EE Sbjct: 2279 QVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE----EETESLSDEEE-EEESCSL 2333 Query: 123 QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM 155 +EE +E+E + E++ K+QEQ K E++ Sbjct: 2334 EEEVDREKEILKKEKQFKLQEQRRKSLRGRERV 2366 Score = 62.0 bits (149), Expect = 4e-10 Identities = 40/173 (23%), Positives = 99/173 (57%), Gaps = 10/173 (5%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63 +ER+ +K++ + + + + + + EEK+ +++E + +++EK+ E E+K+ + E+ + Sbjct: 1864 KERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSL 1923 Query: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ-- 121 +++EK+ +++ ++ M + +RLR + + +E+K E K+ EEKM+ Sbjct: 1924 AKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALN-----LEMKRLAEEKMRLV 1978 Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 174 E +E + + E ++ KM + E++++E++ + EEK+ E+++ EE Sbjct: 1979 EGKETLSKGETPETSRQRKMTQVEQELFERKLSL---EEKILLHEDRILAMEE 2028 Score = 57.8 bits (138), Expect = 8e-09 Identities = 42/207 (20%), Positives = 102/207 (49%), Gaps = 28/207 (13%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ----EEKMW 57 +EE+ + K++ EE+ + E +E + + E ++ KM + E+++ E+ EEK+ Sbjct: 1958 KEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKIL 2017 Query: 58 EQEEKMWEQEEKMWEQQRLP-EQKEKMWEQDER---------LREKEERMREQKMWQQVE 107 E+++ EE + +L + ++++ Q +R ++++E +E ++ Sbjct: 2018 LHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKIL 2077 Query: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKM----WE----------QEE 153 K +K E K+ ++E KM + + ++ +E ++ ++ K+ W+ E+ Sbjct: 2078 KALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEK 2137 Query: 154 KMREQEEKMREQEEKMQGQEEKMRDVE 180 K+ ++ K+ + +M +EEKM + E Sbjct: 2138 KLARKQRKLANKMRRMINKEEKMTEEE 2164 Score = 56.2 bits (134), Expect = 2e-08 Identities = 38/185 (20%), Positives = 103/185 (55%), Gaps = 16/185 (8%) Query: 11 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ------EEKMWEQEEKMW 64 E+K+ +E+E + +++EK+ E E+K+ + E+ + +++EK+ ++ E+ M + ++++ Sbjct: 1892 EEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLR 1951 Query: 65 EQEEKMWEQQRLPEQKEKMWEQDERLREKEERM---------REQKMWQQVEKMREKKKT 115 + + E++ L + +++ E+ RL E +E + R++KM Q +++ E+K + Sbjct: 1952 GELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLS 2011 Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQ-EEKMREQEEKMREQEEKMQGQEE 174 EEK+ E+++ EE + + + ++++ Q + K+ + K+ ++ E + + Sbjct: 2012 LEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPA 2071 Query: 175 KMRDV 179 K+ + Sbjct: 2072 KLNKI 2076 Score = 41.2 bits (95), Expect = 8e-04 Identities = 46/199 (23%), Positives = 89/199 (44%), Gaps = 55/199 (27%) Query: 24 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKM 83 +E+ +Q +++ +E M +EE+ Q++ M EE Q L + K+ + Sbjct: 1325 REDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEET----------QVILKKGKKVI 1374 Query: 84 WEQD------ERLREKEERMREQKMWQQ----VEKMREKKKTQEEKMQEQEEKMQEQEEM 133 + + + + +KEE+ QK +Q V+K R+ K + E M ++E M E+ E Sbjct: 1375 FLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKRE-MTKEERDMSEEVEE 1433 Query: 134 MWEQEEKMQEQEEKM------------------WEQ----------------EEKMREQE 159 M EEK+ +QE K+ W+Q E+++ ++E Sbjct: 1434 MATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEE 1493 Query: 160 EKMREQEEKMQGQEEKMRD 178 EK+ + EK+ +EE +++ Sbjct: 1494 EKLHQAGEKLSPEEEMLQE 1512 >gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens] Length = 1293 Score = 94.7 bits (234), Expect = 6e-20 Identities = 56/174 (32%), Positives = 102/174 (58%), Gaps = 14/174 (8%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63 E+ RE E + + EEE + QEE ++QEE +R Q+E E+ ++ +E+E +QEE + Sbjct: 732 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKRREEEELARRKQEEAL 788 Query: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123 Q E+ +R E++E+ +Q+E LR EER RE+ E+++ QEE +++Q Sbjct: 789 RRQREQEIALRRQREEEERQ-QQEEALRRLEERRREE----------EERRKQEELLRKQ 837 Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 EE+ + E + +++E +M E+ ++R +EE+ + +E ++Q Q+E MR Sbjct: 838 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 891 Score = 93.2 bits (230), Expect = 2e-19 Identities = 67/210 (31%), Positives = 121/210 (57%), Gaps = 38/210 (18%) Query: 2 REEERMRERE-----KKMREEEEMMREQ--EEKMQEQEEKMREQEEKMWEQEEKMQEQEE 54 REEE + R+ ++ RE+E +R Q EE+ Q+QEE +R EE+ E+EE+ ++QEE Sbjct: 774 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQEE 832 Query: 55 KMWEQEEK--MWEQEEKMWEQQRLPEQKEKMWEQDERLR--EKEERMREQKMWQQVEKMR 110 + +QEE+ W +EE+ Q+RL E + +M E+ RLR E+E + +E ++ +Q E MR Sbjct: 833 LLRKQEEEAAKWAREEEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 891 Query: 111 EKKKTQEEKMQEQEEKMQEQEEMM-------WEQE-----------------EKMQEQEE 146 ++++ QE + Q+++ Q+Q M W Q+ +K++E+ E Sbjct: 892 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 951 Query: 147 KMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 + +EE+ R+Q E M+ +++ Q Q++K+ Sbjct: 952 RQL-REEQRRQQRELMKALQQQQQQQQQKL 980 Score = 74.3 bits (181), Expect = 8e-14 Identities = 53/165 (32%), Positives = 96/165 (58%), Gaps = 16/165 (9%) Query: 18 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 77 E++ + ++ K + E++ RE E + +EE+ + QEE +QEE + Q+E+ E++R Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE--ERKRRE 775 Query: 78 EQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQ 137 E++ +Q+E LR R REQ++ + ++ E+++ QEE ++ EE+ +E+EE +Q Sbjct: 776 EEELARRKQEEALR----RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR-KQ 830 Query: 138 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPA 182 EE +++QEE E + RE+EE R EE ++R E A Sbjct: 831 EELLRKQEE---EAAKWAREEEEAQRRLEEN------RLRMEEEA 866 Score = 73.2 bits (178), Expect = 2e-13 Identities = 44/195 (22%), Positives = 104/195 (53%), Gaps = 22/195 (11%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 REEE R++E+ +R++EE + + +E + ++ E +M E+ +++ +EE+ +E Sbjct: 822 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 881 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEKMR 110 ++ Q+E M ++Q+ E ++ +Q ++ + + ++ W Q + Sbjct: 882 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 941 Query: 111 EKKKTQEEK-MQEQEEKMQEQEEMMWEQEEKMQEQEEKM--WEQEEK--------MREQE 159 E +K +EE+ Q +EE+ ++Q E+M +++ Q+Q++K+ W K + Q+ Sbjct: 942 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1001 Query: 160 EKMREQEEKMQGQEE 174 E+ R+ +++ Q Q++ Sbjct: 1002 EEARQMQKQQQQQQQ 1016 Score = 60.1 bits (144), Expect = 2e-09 Identities = 38/159 (23%), Positives = 81/159 (50%), Gaps = 25/159 (15%) Query: 6 RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE----QEEKMQEQEEKMWEQEE 61 RM E ++R EEE + +E ++Q Q+E MR+++++ Q+++ Q+Q +M Sbjct: 861 RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 920 Query: 62 KMWEQEE-----------KMWEQQRLPEQKEKMWEQDERLREKE--------ERMREQKM 102 W Q+ + E Q+L E++E+ +++R +++E ++ ++QK+ Sbjct: 921 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 980 Query: 103 --WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE 139 W V K K+ E QE+ +MQ+Q++ + ++ Sbjct: 981 SGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1019 Score = 43.5 bits (101), Expect = 2e-04 Identities = 41/193 (21%), Positives = 94/193 (48%), Gaps = 27/193 (13%) Query: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM---QEQEEKMWEQEEKMWE 65 ++E+ R++E Q + +Q Q+ +++Q ++ Q++K +Q++++ ++ Sbjct: 600 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659 Query: 66 QEEKMWEQQRLPEQKEKMWEQDE-RLREKEERMREQKMWQ----------------QVEK 108 + ++ +Q +P + D + E + + +W+ +E+ Sbjct: 660 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 719 Query: 109 MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR---EQEEKMREQ 165 +++ +K + K+ E++ +E E +EE+ + QEE +QEE +R E+E K RE+ Sbjct: 720 LQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 776 Query: 166 EE-KMQGQEEKMR 177 EE + QEE +R Sbjct: 777 EELARRKQEEALR 789 Score = 38.1 bits (87), Expect = 0.007 Identities = 20/76 (26%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Query: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKM--WEQEEKMQEQEEKMWEQEEKMWEQ 66 ERE+++REE+ R+Q E M+ +++ ++Q++K+ W K + + E +++ Q Sbjct: 949 ERERQLREEQR--RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1006 Query: 67 EEKMWEQQRLPEQKEK 82 +K +QQ+ +Q + Sbjct: 1007 MQKQQQQQQQHQQPNR 1022 Score = 33.5 bits (75), Expect = 0.17 Identities = 15/85 (17%), Positives = 45/85 (52%) Query: 14 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 73 + E +++ E+E +++E++ + + + K +Q+++ Q+Q+ W K + + E Sbjct: 940 LAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEI 999 Query: 74 QRLPEQKEKMWEQDERLREKEERMR 98 Q+ ++ + +Q ++ ++ R R Sbjct: 1000 QQEEARQMQKQQQQQQQHQQPNRAR 1024 Score = 32.7 bits (73), Expect = 0.28 Identities = 44/227 (19%), Positives = 92/227 (40%), Gaps = 35/227 (15%) Query: 3 EEERMREREKKMREEEEMMREQE---EKMQEQEEKMREQEEKMWE--QEEKMQEQEEKMW 57 EE R EK R++ +E + + E +R + E W +EE+ E E+ W Sbjct: 162 EERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESEN-WRIFREEQNGEDEDGGW 220 Query: 58 E-----QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQ-QVEKMRE 111 ++ + W W + ++ + +E D R R+ E R + ++ R+ Sbjct: 221 RLAGSRRDGERWRPHSPGWREHM---ERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRD 277 Query: 112 KK-----KTQEEKM-------------QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEE 153 + EE+M + Q+E + E++EM + ++ +E + E Sbjct: 278 SLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNE 337 Query: 154 KMREQEEKMREQEEKMQ--GQEEKMRDVEPAGGEAGEGSPQDNPTAQ 198 + +E ++ +++ EK G E + + A G+P D+ + + Sbjct: 338 EAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQE 384 Score = 28.1 bits (61), Expect = 7.0 Identities = 18/103 (17%), Positives = 50/103 (48%), Gaps = 9/103 (8%) Query: 16 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 75 E + +R E +E ++ E+ +Q+ Q Q++++ +Q+ Q++ + + Sbjct: 1163 EVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQ-----QQQPPQQPPQ 1217 Query: 76 LPEQKEKMWEQD----ERLREKEERMREQKMWQQVEKMREKKK 114 P+Q++ +W + + + + +Q ++ V+ ++KKK Sbjct: 1218 QPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKK 1260 Score = 27.7 bits (60), Expect = 9.1 Identities = 16/89 (17%), Positives = 41/89 (46%), Gaps = 12/89 (13%) Query: 104 QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE----------QEE 153 +Q + R K+K +++ Q+Q + Q+Q+ +Q + +Q++ +W Q Sbjct: 1183 KQFLERRAKQKANQQRQQQQLPQQQQQQPP--QQPPQQPQQQDSVWGMNHSTLHSVFQTN 1240 Query: 154 KMREQEEKMREQEEKMQGQEEKMRDVEPA 182 + Q+ + + +++KM +P+ Sbjct: 1241 QSNNQQSNFEAVQSGKKKKKQKMVRADPS 1269 >gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens] Length = 1320 Score = 94.7 bits (234), Expect = 6e-20 Identities = 56/174 (32%), Positives = 102/174 (58%), Gaps = 14/174 (8%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63 E+ RE E + + EEE + QEE ++QEE +R Q+E E+ ++ +E+E +QEE + Sbjct: 759 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKRREEEELARRKQEEAL 815 Query: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123 Q E+ +R E++E+ +Q+E LR EER RE+ E+++ QEE +++Q Sbjct: 816 RRQREQEIALRRQREEEERQ-QQEEALRRLEERRREE----------EERRKQEELLRKQ 864 Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 EE+ + E + +++E +M E+ ++R +EE+ + +E ++Q Q+E MR Sbjct: 865 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 918 Score = 93.2 bits (230), Expect = 2e-19 Identities = 67/210 (31%), Positives = 121/210 (57%), Gaps = 38/210 (18%) Query: 2 REEERMRERE-----KKMREEEEMMREQ--EEKMQEQEEKMREQEEKMWEQEEKMQEQEE 54 REEE + R+ ++ RE+E +R Q EE+ Q+QEE +R EE+ E+EE+ ++QEE Sbjct: 801 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQEE 859 Query: 55 KMWEQEEK--MWEQEEKMWEQQRLPEQKEKMWEQDERLR--EKEERMREQKMWQQVEKMR 110 + +QEE+ W +EE+ Q+RL E + +M E+ RLR E+E + +E ++ +Q E MR Sbjct: 860 LLRKQEEEAAKWAREEEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 918 Query: 111 EKKKTQEEKMQEQEEKMQEQEEMM-------WEQE-----------------EKMQEQEE 146 ++++ QE + Q+++ Q+Q M W Q+ +K++E+ E Sbjct: 919 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 978 Query: 147 KMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 + +EE+ R+Q E M+ +++ Q Q++K+ Sbjct: 979 RQL-REEQRRQQRELMKALQQQQQQQQQKL 1007 Score = 74.3 bits (181), Expect = 8e-14 Identities = 53/165 (32%), Positives = 96/165 (58%), Gaps = 16/165 (9%) Query: 18 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 77 E++ + ++ K + E++ RE E + +EE+ + QEE +QEE + Q+E+ E++R Sbjct: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE--ERKRRE 802 Query: 78 EQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQ 137 E++ +Q+E LR R REQ++ + ++ E+++ QEE ++ EE+ +E+EE +Q Sbjct: 803 EEELARRKQEEALR----RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR-KQ 857 Query: 138 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPA 182 EE +++QEE E + RE+EE R EE ++R E A Sbjct: 858 EELLRKQEE---EAAKWAREEEEAQRRLEEN------RLRMEEEA 893 Score = 73.2 bits (178), Expect = 2e-13 Identities = 44/195 (22%), Positives = 104/195 (53%), Gaps = 22/195 (11%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 REEE R++E+ +R++EE + + +E + ++ E +M E+ +++ +EE+ +E Sbjct: 849 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 908 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEKMR 110 ++ Q+E M ++Q+ E ++ +Q ++ + + ++ W Q + Sbjct: 909 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 968 Query: 111 EKKKTQEEK-MQEQEEKMQEQEEMMWEQEEKMQEQEEKM--WEQEEK--------MREQE 159 E +K +EE+ Q +EE+ ++Q E+M +++ Q+Q++K+ W K + Q+ Sbjct: 969 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1028 Query: 160 EKMREQEEKMQGQEE 174 E+ R+ +++ Q Q++ Sbjct: 1029 EEARQMQKQQQQQQQ 1043 Score = 60.1 bits (144), Expect = 2e-09 Identities = 38/159 (23%), Positives = 81/159 (50%), Gaps = 25/159 (15%) Query: 6 RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE----QEEKMQEQEEKMWEQEE 61 RM E ++R EEE + +E ++Q Q+E MR+++++ Q+++ Q+Q +M Sbjct: 888 RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 947 Query: 62 KMWEQEE-----------KMWEQQRLPEQKEKMWEQDERLREKE--------ERMREQKM 102 W Q+ + E Q+L E++E+ +++R +++E ++ ++QK+ Sbjct: 948 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 1007 Query: 103 --WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE 139 W V K K+ E QE+ +MQ+Q++ + ++ Sbjct: 1008 SGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1046 Score = 58.5 bits (140), Expect = 5e-09 Identities = 48/206 (23%), Positives = 102/206 (49%), Gaps = 52/206 (25%) Query: 2 REEERMREREKKM----REEEEMMREQEE---KMQEQEEKMREQEEKMWEQEEKMQEQEE 54 ++EE +R++E++ REEEE R EE +M+E+ ++R +EE+ +E ++Q Q+E Sbjct: 856 KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 915 Query: 55 KMWEQEEKM-------WEQEEKMWEQQRLPEQK----------------------EKMWE 85 M +++++ +Q+++ Q +LP +K+ E Sbjct: 916 LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 975 Query: 86 QDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQE 145 + ER + +EE+ R+Q RE K +++ Q+Q++K+ W K Sbjct: 976 ERER-QLREEQRRQQ---------RELMKALQQQQQQQQQKLSG-----WGNVSKPSGTT 1020 Query: 146 EKMWE-QEEKMREQEEKMREQEEKMQ 170 + + E Q+E+ R+ +++ ++Q++ Q Sbjct: 1021 KSLLEIQQEEARQMQKQQQQQQQHQQ 1046 Score = 43.5 bits (101), Expect = 2e-04 Identities = 41/193 (21%), Positives = 94/193 (48%), Gaps = 27/193 (13%) Query: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM---QEQEEKMWEQEEKMWE 65 ++E+ R++E Q + +Q Q+ +++Q ++ Q++K +Q++++ ++ Sbjct: 627 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686 Query: 66 QEEKMWEQQRLPEQKEKMWEQDE-RLREKEERMREQKMWQ----------------QVEK 108 + ++ +Q +P + D + E + + +W+ +E+ Sbjct: 687 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 746 Query: 109 MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR---EQEEKMREQ 165 +++ +K + K+ E++ +E E +EE+ + QEE +QEE +R E+E K RE+ Sbjct: 747 LQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 803 Query: 166 EE-KMQGQEEKMR 177 EE + QEE +R Sbjct: 804 EELARRKQEEALR 816 Score = 38.1 bits (87), Expect = 0.007 Identities = 20/76 (26%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Query: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKM--WEQEEKMQEQEEKMWEQEEKMWEQ 66 ERE+++REE+ R+Q E M+ +++ ++Q++K+ W K + + E +++ Q Sbjct: 976 ERERQLREEQR--RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1033 Query: 67 EEKMWEQQRLPEQKEK 82 +K +QQ+ +Q + Sbjct: 1034 MQKQQQQQQQHQQPNR 1049 Score = 33.5 bits (75), Expect = 0.17 Identities = 15/85 (17%), Positives = 45/85 (52%) Query: 14 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 73 + E +++ E+E +++E++ + + + K +Q+++ Q+Q+ W K + + E Sbjct: 967 LAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEI 1026 Query: 74 QRLPEQKEKMWEQDERLREKEERMR 98 Q+ ++ + +Q ++ ++ R R Sbjct: 1027 QQEEARQMQKQQQQQQQHQQPNRAR 1051 Score = 28.1 bits (61), Expect = 7.0 Identities = 18/103 (17%), Positives = 50/103 (48%), Gaps = 9/103 (8%) Query: 16 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 75 E + +R E +E ++ E+ +Q+ Q Q++++ +Q+ Q++ + + Sbjct: 1190 EVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQ-----QQQPPQQPPQ 1244 Query: 76 LPEQKEKMWEQD----ERLREKEERMREQKMWQQVEKMREKKK 114 P+Q++ +W + + + + +Q ++ V+ ++KKK Sbjct: 1245 QPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKK 1287 Score = 27.7 bits (60), Expect = 9.1 Identities = 16/89 (17%), Positives = 41/89 (46%), Gaps = 12/89 (13%) Query: 104 QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE----------QEE 153 +Q + R K+K +++ Q+Q + Q+Q+ +Q + +Q++ +W Q Sbjct: 1210 KQFLERRAKQKANQQRQQQQLPQQQQQQPP--QQPPQQPQQQDSVWGMNHSTLHSVFQTN 1267 Query: 154 KMREQEEKMREQEEKMQGQEEKMRDVEPA 182 + Q+ + + +++KM +P+ Sbjct: 1268 QSNNQQSNFEAVQSGKKKKKQKMVRADPS 1296 >gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 94.7 bits (234), Expect = 6e-20 Identities = 56/174 (32%), Positives = 102/174 (58%), Gaps = 14/174 (8%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63 E+ RE E + + EEE + QEE ++QEE +R Q+E E+ ++ +E+E +QEE + Sbjct: 738 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKRREEEELARRKQEEAL 794 Query: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123 Q E+ +R E++E+ +Q+E LR EER RE+ E+++ QEE +++Q Sbjct: 795 RRQREQEIALRRQREEEERQ-QQEEALRRLEERRREE----------EERRKQEELLRKQ 843 Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 EE+ + E + +++E +M E+ ++R +EE+ + +E ++Q Q+E MR Sbjct: 844 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897 Score = 93.2 bits (230), Expect = 2e-19 Identities = 67/210 (31%), Positives = 121/210 (57%), Gaps = 38/210 (18%) Query: 2 REEERMRERE-----KKMREEEEMMREQ--EEKMQEQEEKMREQEEKMWEQEEKMQEQEE 54 REEE + R+ ++ RE+E +R Q EE+ Q+QEE +R EE+ E+EE+ ++QEE Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQEE 838 Query: 55 KMWEQEEK--MWEQEEKMWEQQRLPEQKEKMWEQDERLR--EKEERMREQKMWQQVEKMR 110 + +QEE+ W +EE+ Q+RL E + +M E+ RLR E+E + +E ++ +Q E MR Sbjct: 839 LLRKQEEEAAKWAREEEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897 Query: 111 EKKKTQEEKMQEQEEKMQEQEEMM-------WEQE-----------------EKMQEQEE 146 ++++ QE + Q+++ Q+Q M W Q+ +K++E+ E Sbjct: 898 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 957 Query: 147 KMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 + +EE+ R+Q E M+ +++ Q Q++K+ Sbjct: 958 RQL-REEQRRQQRELMKALQQQQQQQQQKL 986 Score = 74.3 bits (181), Expect = 8e-14 Identities = 53/165 (32%), Positives = 96/165 (58%), Gaps = 16/165 (9%) Query: 18 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 77 E++ + ++ K + E++ RE E + +EE+ + QEE +QEE + Q+E+ E++R Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE--ERKRRE 781 Query: 78 EQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQ 137 E++ +Q+E LR R REQ++ + ++ E+++ QEE ++ EE+ +E+EE +Q Sbjct: 782 EEELARRKQEEALR----RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR-KQ 836 Query: 138 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPA 182 EE +++QEE E + RE+EE R EE ++R E A Sbjct: 837 EELLRKQEE---EAAKWAREEEEAQRRLEEN------RLRMEEEA 872 Score = 73.2 bits (178), Expect = 2e-13 Identities = 44/195 (22%), Positives = 104/195 (53%), Gaps = 22/195 (11%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 REEE R++E+ +R++EE + + +E + ++ E +M E+ +++ +EE+ +E Sbjct: 828 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEKMR 110 ++ Q+E M ++Q+ E ++ +Q ++ + + ++ W Q + Sbjct: 888 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 947 Query: 111 EKKKTQEEK-MQEQEEKMQEQEEMMWEQEEKMQEQEEKM--WEQEEK--------MREQE 159 E +K +EE+ Q +EE+ ++Q E+M +++ Q+Q++K+ W K + Q+ Sbjct: 948 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1007 Query: 160 EKMREQEEKMQGQEE 174 E+ R+ +++ Q Q++ Sbjct: 1008 EEARQMQKQQQQQQQ 1022 Score = 60.1 bits (144), Expect = 2e-09 Identities = 38/159 (23%), Positives = 81/159 (50%), Gaps = 25/159 (15%) Query: 6 RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE----QEEKMQEQEEKMWEQEE 61 RM E ++R EEE + +E ++Q Q+E MR+++++ Q+++ Q+Q +M Sbjct: 867 RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 926 Query: 62 KMWEQEE-----------KMWEQQRLPEQKEKMWEQDERLREKE--------ERMREQKM 102 W Q+ + E Q+L E++E+ +++R +++E ++ ++QK+ Sbjct: 927 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 986 Query: 103 --WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE 139 W V K K+ E QE+ +MQ+Q++ + ++ Sbjct: 987 SGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1025 Score = 43.5 bits (101), Expect = 2e-04 Identities = 41/193 (21%), Positives = 94/193 (48%), Gaps = 27/193 (13%) Query: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM---QEQEEKMWEQEEKMWE 65 ++E+ R++E Q + +Q Q+ +++Q ++ Q++K +Q++++ ++ Sbjct: 606 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665 Query: 66 QEEKMWEQQRLPEQKEKMWEQDE-RLREKEERMREQKMWQ----------------QVEK 108 + ++ +Q +P + D + E + + +W+ +E+ Sbjct: 666 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 725 Query: 109 MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR---EQEEKMREQ 165 +++ +K + K+ E++ +E E +EE+ + QEE +QEE +R E+E K RE+ Sbjct: 726 LQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 782 Query: 166 EE-KMQGQEEKMR 177 EE + QEE +R Sbjct: 783 EELARRKQEEALR 795 Score = 38.1 bits (87), Expect = 0.007 Identities = 20/76 (26%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Query: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKM--WEQEEKMQEQEEKMWEQEEKMWEQ 66 ERE+++REE+ R+Q E M+ +++ ++Q++K+ W K + + E +++ Q Sbjct: 955 ERERQLREEQR--RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1012 Query: 67 EEKMWEQQRLPEQKEK 82 +K +QQ+ +Q + Sbjct: 1013 MQKQQQQQQQHQQPNR 1028 Score = 33.5 bits (75), Expect = 0.17 Identities = 15/85 (17%), Positives = 45/85 (52%) Query: 14 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 73 + E +++ E+E +++E++ + + + K +Q+++ Q+Q+ W K + + E Sbjct: 946 LAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEI 1005 Query: 74 QRLPEQKEKMWEQDERLREKEERMR 98 Q+ ++ + +Q ++ ++ R R Sbjct: 1006 QQEEARQMQKQQQQQQQHQQPNRAR 1030 Score = 29.3 bits (64), Expect = 3.1 Identities = 16/78 (20%), Positives = 38/78 (48%), Gaps = 2/78 (2%) Query: 123 QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ--GQEEKMRDVE 180 Q+E + E++EM + ++ +E + E+ +E ++ +++ EK G E + Sbjct: 313 QKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQ 372 Query: 181 PAGGEAGEGSPQDNPTAQ 198 + A G+P D+ + + Sbjct: 373 TSSSSARPGTPSDHQSQE 390 Score = 28.1 bits (61), Expect = 7.0 Identities = 18/103 (17%), Positives = 50/103 (48%), Gaps = 9/103 (8%) Query: 16 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 75 E + +R E +E ++ E+ +Q+ Q Q++++ +Q+ Q++ + + Sbjct: 1169 EVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQ-----QQQPPQQPPQ 1223 Query: 76 LPEQKEKMWEQD----ERLREKEERMREQKMWQQVEKMREKKK 114 P+Q++ +W + + + + +Q ++ V+ ++KKK Sbjct: 1224 QPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKK 1266 Score = 27.7 bits (60), Expect = 9.1 Identities = 16/89 (17%), Positives = 41/89 (46%), Gaps = 12/89 (13%) Query: 104 QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE----------QEE 153 +Q + R K+K +++ Q+Q + Q+Q+ +Q + +Q++ +W Q Sbjct: 1189 KQFLERRAKQKANQQRQQQQLPQQQQQQPP--QQPPQQPQQQDSVWGMNHSTLHSVFQTN 1246 Query: 154 KMREQEEKMREQEEKMQGQEEKMRDVEPA 182 + Q+ + + +++KM +P+ Sbjct: 1247 QSNNQQSNFEAVQSGKKKKKQKMVRADPS 1275 >gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 94.7 bits (234), Expect = 6e-20 Identities = 56/174 (32%), Positives = 102/174 (58%), Gaps = 14/174 (8%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63 E+ RE E + + EEE + QEE ++QEE +R Q+E E+ ++ +E+E +QEE + Sbjct: 738 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKRREEEELARRKQEEAL 794 Query: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123 Q E+ +R E++E+ +Q+E LR EER RE+ E+++ QEE +++Q Sbjct: 795 RRQREQEIALRRQREEEERQ-QQEEALRRLEERRREE----------EERRKQEELLRKQ 843 Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 EE+ + E + +++E +M E+ ++R +EE+ + +E ++Q Q+E MR Sbjct: 844 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897 Score = 93.2 bits (230), Expect = 2e-19 Identities = 67/210 (31%), Positives = 121/210 (57%), Gaps = 38/210 (18%) Query: 2 REEERMRERE-----KKMREEEEMMREQ--EEKMQEQEEKMREQEEKMWEQEEKMQEQEE 54 REEE + R+ ++ RE+E +R Q EE+ Q+QEE +R EE+ E+EE+ ++QEE Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQEE 838 Query: 55 KMWEQEEK--MWEQEEKMWEQQRLPEQKEKMWEQDERLR--EKEERMREQKMWQQVEKMR 110 + +QEE+ W +EE+ Q+RL E + +M E+ RLR E+E + +E ++ +Q E MR Sbjct: 839 LLRKQEEEAAKWAREEEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897 Query: 111 EKKKTQEEKMQEQEEKMQEQEEMM-------WEQE-----------------EKMQEQEE 146 ++++ QE + Q+++ Q+Q M W Q+ +K++E+ E Sbjct: 898 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 957 Query: 147 KMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 + +EE+ R+Q E M+ +++ Q Q++K+ Sbjct: 958 RQL-REEQRRQQRELMKALQQQQQQQQQKL 986 Score = 74.3 bits (181), Expect = 8e-14 Identities = 53/165 (32%), Positives = 96/165 (58%), Gaps = 16/165 (9%) Query: 18 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 77 E++ + ++ K + E++ RE E + +EE+ + QEE +QEE + Q+E+ E++R Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE--ERKRRE 781 Query: 78 EQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQ 137 E++ +Q+E LR R REQ++ + ++ E+++ QEE ++ EE+ +E+EE +Q Sbjct: 782 EEELARRKQEEALR----RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR-KQ 836 Query: 138 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPA 182 EE +++QEE E + RE+EE R EE ++R E A Sbjct: 837 EELLRKQEE---EAAKWAREEEEAQRRLEEN------RLRMEEEA 872 Score = 73.2 bits (178), Expect = 2e-13 Identities = 44/195 (22%), Positives = 104/195 (53%), Gaps = 22/195 (11%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 REEE R++E+ +R++EE + + +E + ++ E +M E+ +++ +EE+ +E Sbjct: 828 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEKMR 110 ++ Q+E M ++Q+ E ++ +Q ++ + + ++ W Q + Sbjct: 888 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 947 Query: 111 EKKKTQEEK-MQEQEEKMQEQEEMMWEQEEKMQEQEEKM--WEQEEK--------MREQE 159 E +K +EE+ Q +EE+ ++Q E+M +++ Q+Q++K+ W K + Q+ Sbjct: 948 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1007 Query: 160 EKMREQEEKMQGQEE 174 E+ R+ +++ Q Q++ Sbjct: 1008 EEARQMQKQQQQQQQ 1022 Score = 60.1 bits (144), Expect = 2e-09 Identities = 38/159 (23%), Positives = 81/159 (50%), Gaps = 25/159 (15%) Query: 6 RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE----QEEKMQEQEEKMWEQEE 61 RM E ++R EEE + +E ++Q Q+E MR+++++ Q+++ Q+Q +M Sbjct: 867 RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 926 Query: 62 KMWEQEE-----------KMWEQQRLPEQKEKMWEQDERLREKE--------ERMREQKM 102 W Q+ + E Q+L E++E+ +++R +++E ++ ++QK+ Sbjct: 927 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 986 Query: 103 --WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE 139 W V K K+ E QE+ +MQ+Q++ + ++ Sbjct: 987 SGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1025 Score = 43.5 bits (101), Expect = 2e-04 Identities = 41/193 (21%), Positives = 94/193 (48%), Gaps = 27/193 (13%) Query: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM---QEQEEKMWEQEEKMWE 65 ++E+ R++E Q + +Q Q+ +++Q ++ Q++K +Q++++ ++ Sbjct: 606 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665 Query: 66 QEEKMWEQQRLPEQKEKMWEQDE-RLREKEERMREQKMWQ----------------QVEK 108 + ++ +Q +P + D + E + + +W+ +E+ Sbjct: 666 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 725 Query: 109 MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR---EQEEKMREQ 165 +++ +K + K+ E++ +E E +EE+ + QEE +QEE +R E+E K RE+ Sbjct: 726 LQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 782 Query: 166 EE-KMQGQEEKMR 177 EE + QEE +R Sbjct: 783 EELARRKQEEALR 795 Score = 38.1 bits (87), Expect = 0.007 Identities = 20/76 (26%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Query: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKM--WEQEEKMQEQEEKMWEQEEKMWEQ 66 ERE+++REE+ R+Q E M+ +++ ++Q++K+ W K + + E +++ Q Sbjct: 955 ERERQLREEQR--RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1012 Query: 67 EEKMWEQQRLPEQKEK 82 +K +QQ+ +Q + Sbjct: 1013 MQKQQQQQQQHQQPNR 1028 Score = 33.5 bits (75), Expect = 0.17 Identities = 15/85 (17%), Positives = 45/85 (52%) Query: 14 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 73 + E +++ E+E +++E++ + + + K +Q+++ Q+Q+ W K + + E Sbjct: 946 LAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEI 1005 Query: 74 QRLPEQKEKMWEQDERLREKEERMR 98 Q+ ++ + +Q ++ ++ R R Sbjct: 1006 QQEEARQMQKQQQQQQQHQQPNRAR 1030 Score = 29.3 bits (64), Expect = 3.1 Identities = 16/78 (20%), Positives = 38/78 (48%), Gaps = 2/78 (2%) Query: 123 QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ--GQEEKMRDVE 180 Q+E + E++EM + ++ +E + E+ +E ++ +++ EK G E + Sbjct: 313 QKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQ 372 Query: 181 PAGGEAGEGSPQDNPTAQ 198 + A G+P D+ + + Sbjct: 373 TSSSSARPGTPSDHQSQE 390 Score = 28.1 bits (61), Expect = 7.0 Identities = 18/103 (17%), Positives = 50/103 (48%), Gaps = 9/103 (8%) Query: 16 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 75 E + +R E +E ++ E+ +Q+ Q Q++++ +Q+ Q++ + + Sbjct: 1169 EVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQ-----QQQPPQQPPQ 1223 Query: 76 LPEQKEKMWEQD----ERLREKEERMREQKMWQQVEKMREKKK 114 P+Q++ +W + + + + +Q ++ V+ ++KKK Sbjct: 1224 QPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKK 1266 Score = 27.7 bits (60), Expect = 9.1 Identities = 16/89 (17%), Positives = 41/89 (46%), Gaps = 12/89 (13%) Query: 104 QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE----------QEE 153 +Q + R K+K +++ Q+Q + Q+Q+ +Q + +Q++ +W Q Sbjct: 1189 KQFLERRAKQKANQQRQQQQLPQQQQQQPP--QQPPQQPQQQDSVWGMNHSTLHSVFQTN 1246 Query: 154 KMREQEEKMREQEEKMQGQEEKMRDVEPA 182 + Q+ + + +++KM +P+ Sbjct: 1247 QSNNQQSNFEAVQSGKKKKKQKMVRADPS 1275 >gi|95147555 microtubule-associated protein 1A [Homo sapiens] Length = 2803 Score = 94.4 bits (233), Expect = 8e-20 Identities = 64/242 (26%), Positives = 122/242 (50%), Gaps = 43/242 (17%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 + E+++ E++ K+ EE++ EQ++ EQ++K E ++K EQ++++ EQ+EK+ E++ Sbjct: 1436 LEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEK 1495 Query: 61 EKMWEQEEKMWEQQ------------------RLPEQKEKMWEQDERLREKEERMREQKM 102 +K +Q+ + E + + PEQK + EQ +++ EK+++ EQK Sbjct: 1496 DKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKY 1555 Query: 103 W----------QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKM---- 148 W Q ++ + E +TQE++ QE+K ++ + + + EK++ EEK+ Sbjct: 1556 WALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALL 1615 Query: 149 -----------WEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTA 197 QE + REQEEK ++ +Q +E E GE E +P T+ Sbjct: 1616 EKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTS 1675 Query: 198 QE 199 E Sbjct: 1676 PE 1677 Score = 89.0 bits (219), Expect = 3e-18 Identities = 51/184 (27%), Positives = 111/184 (60%), Gaps = 11/184 (5%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 ++++++ E++ + E+++ EQ++K E ++K E+++K EQ++K+ E+++K EQ+ Sbjct: 1401 VKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQK 1460 Query: 61 EKMWEQEEKMWE-QQRLPEQKEKMWEQDERLREKEERMREQKM--------WQQVEKMRE 111 + EQ++K E + + EQK+++ EQ E++ E++++ +QK+ V +M++ Sbjct: 1461 DTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKD 1520 Query: 112 KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG 171 + Q +K EQ+ + QEQ++ + E+K Q E+K W +K E+ ++ EE Q Sbjct: 1521 RDLEQTDKAPEQKHQAQEQKDKV--SEKKDQALEQKYWALGQKDEALEQNIQALEENHQT 1578 Query: 172 QEEK 175 QE++ Sbjct: 1579 QEQE 1582 Score = 76.6 bits (187), Expect = 2e-14 Identities = 52/215 (24%), Positives = 117/215 (54%), Gaps = 17/215 (7%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 + +E + ++ + +++E + + E +++Q++ + EQ+ + EQ++ EQ++K E + Sbjct: 1374 LEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKAL-EQKGRDLEQKDTALEQKDKALEPK 1432 Query: 61 EKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK---------MWQQVEKM- 109 +K E+++K EQ+ ++PE+K+K EQ + E++++ E K + +Q EK+ Sbjct: 1433 DKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIP 1492 Query: 110 REKKKTQEEKMQEQEEK-----MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164 EK K ++K++ E K + E ++ EQ +K EQ+ + EQ++K+ E++++ E Sbjct: 1493 EEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALE 1552 Query: 165 QEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199 Q+ GQ+++ + E + + QE Sbjct: 1553 QKYWALGQKDEALEQNIQALEENHQTQEQESLVQE 1587 Score = 75.1 bits (183), Expect = 5e-14 Identities = 45/196 (22%), Positives = 115/196 (58%), Gaps = 7/196 (3%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63 ++R E++K+ ++E++ +Q++K E +E + ++ +++++E + + E + +Q++ + Sbjct: 1350 KDRTSEQKKEPEPKDEVL-QQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKAL 1408 Query: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123 ++ + ++ EQK+K E ++ E++++ EQK ++ + ++K Q++ EQ Sbjct: 1409 EQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQK--DKIPEEKDKALEQKDTALEQ 1466 Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAG 183 ++K E ++ EQ++++ EQ+EK+ E+++K +Q K+R E K E+ + +++ Sbjct: 1467 KDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQ--KVRSVEHK--APEDTVAEMKDRD 1522 Query: 184 GEAGEGSPQDNPTAQE 199 E + +P+ AQE Sbjct: 1523 LEQTDKAPEQKHQAQE 1538 Score = 73.6 bits (179), Expect = 1e-13 Identities = 42/182 (23%), Positives = 112/182 (61%), Gaps = 7/182 (3%) Query: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 ++++++ E ++ + ++ + +++E + + E +++Q++ + EQ+ + EQ++ EQ+ Sbjct: 1367 LQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKAL-EQKGRDLEQKDTALEQK 1425 Query: 61 EKMWEQEEK-MWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119 +K E ++K + E+ + EQK+K+ E+ ++ E+++ EQK + + ++K Q+++ Sbjct: 1426 DKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQK--DKALEPKDKDLEQKDR 1483 Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQ---EEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 + EQ+EK+ E+++ +Q+ + E E+ + E +++ EQ +K EQ+ + Q Q++K+ Sbjct: 1484 VLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKV 1543 Query: 177 RD 178 + Sbjct: 1544 SE 1545 Score = 71.2 bits (173), Expect = 7e-13 Identities = 47/194 (24%), Positives = 107/194 (55%), Gaps = 17/194 (8%) Query: 18 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM-------------WEQEEKMW 64 E++ + E+K+ +++ EQ+++ ++E +Q++++ + ++++E + Sbjct: 1336 EDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALH 1395 Query: 65 EQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQE 124 + E + +Q + EQK + EQ + E++++ E K EK +K Q++K+ E++ Sbjct: 1396 VKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEK--DKALEQKDKIPEEK 1453 Query: 125 EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGG 184 +K EQ++ EQ++K E ++K EQ++++ EQ+EK+ E+++K ++K+R VE Sbjct: 1454 DKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDK--ALDQKVRSVEHKAP 1511 Query: 185 EAGEGSPQDNPTAQ 198 E +D Q Sbjct: 1512 EDTVAEMKDRDLEQ 1525 Score = 62.4 bits (150), Expect = 3e-10 Identities = 48/185 (25%), Positives = 93/185 (50%), Gaps = 22/185 (11%) Query: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ------------EEKMQE 51 E+ + E + + E+ + EQ+ + QEQ++K+ E++++ EQ E+ +Q Sbjct: 1512 EDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQA 1571 Query: 52 QEEKMWEQEEKMWEQEEKMWEQQRLPEQK-EKMWEQDERLREKEERMREQKMWQQVEKMR 110 EE QE++ QE+K + + L E+ EK+ +E+L E+ + + Sbjct: 1572 LEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGL-------- 1623 Query: 111 EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK-M 169 E+ QE + +EQEEK ++++ E +E +EE EQ+E E+ EQ+ + Sbjct: 1624 EESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYW 1683 Query: 170 QGQEE 174 +G+E+ Sbjct: 1684 RGRED 1688 Score = 44.7 bits (104), Expect = 7e-05 Identities = 41/189 (21%), Positives = 84/189 (44%), Gaps = 17/189 (8%) Query: 10 REKKMREEEEMMREQEEKMQEQEEKMREQEEK-MWEQEEKMQEQEEKMWEQEEK------ 62 RE + E++ ++ EE +E+ + EQ + + ++ + EE + Sbjct: 521 RELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSV 580 Query: 63 --MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120 + ++E M E++ +PE E+ +D L E E+ W+ EKK+ + E++ Sbjct: 581 PGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWE------EKKQREAERL 634 Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180 ++ E +E E + +E+ +++ E + E+ E+EE + E Q ++ V Sbjct: 635 PDRTEAREESEPEV--KEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVT 692 Query: 181 PAGGEAGEG 189 P EA G Sbjct: 693 PRSREAFGG 701 Score = 42.0 bits (97), Expect = 5e-04 Identities = 35/171 (20%), Positives = 86/171 (50%), Gaps = 21/171 (12%) Query: 10 REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE-QEEKMQEQEEKMWEQEEKMWEQEE 68 + K+++ + + + K+ ++EE + E +E E +++ + E+K E E Sbjct: 309 KPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSE 368 Query: 69 KMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQ 128 K E+ PE+ + E E L+ ++ ++ + K+ KK +EK+ + EEK Sbjct: 369 KPPEKPAKPERVKT--ESSEALKAEKRKLIKDKVG---------KKHLKEKISKLEEK-- 415 Query: 129 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDV 179 + +EK + ++E+ ++++ R++E+K ++EEK + + +++ + Sbjct: 416 -------KDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKI 459 Score = 41.6 bits (96), Expect = 6e-04 Identities = 38/168 (22%), Positives = 69/168 (41%), Gaps = 14/168 (8%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 +E R RE+E+K +++++E +E +EE EQ+E E+ EQ+ + W E Sbjct: 1629 QEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGRED 1688 Query: 63 MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQE 122 + +++ W + + K+W E + Q + RE E E Sbjct: 1689 VALEQDTYWRELSC---ERKVWFPHE--------LDGQGARPHYTEERESTFLDEGPDDE 1737 Query: 123 QEEKMQEQ-EEMMWEQEEK--MQEQEEKMWEQEEKMREQEEKMREQEE 167 QE ++E W + K + +K E E + E + +EE Sbjct: 1738 QEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEE 1785 Score = 39.3 bits (90), Expect = 0.003 Identities = 28/130 (21%), Positives = 68/130 (52%), Gaps = 5/130 (3%) Query: 2 REEERMREREKKMREE-EEMMREQEEKMQEQEEKMREQEEK----MWEQEEKMQEQEEKM 56 + EE + E K+ R E + + + E+K +E EK E+ K E E ++ ++ K+ Sbjct: 336 KREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKL 395 Query: 57 WEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116 + + +EK+ + + ++++K +++ + +K+E +E+K + E+ R+ K + Sbjct: 396 IKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPE 455 Query: 117 EEKMQEQEEK 126 +K+ + + K Sbjct: 456 LKKISKPDLK 465 Score = 38.1 bits (87), Expect = 0.007 Identities = 44/229 (19%), Positives = 97/229 (42%), Gaps = 39/229 (17%) Query: 5 ERMREREKKMREEEEMMREQEEKMQ----EQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 + + + EKK +E E E+ K + E E ++ ++ K+ + + + +EK+ + E Sbjct: 354 KELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLE 413 Query: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQK-------------MWQQVE 107 EK ++E+K +++R +K++ +++++ +KEE+ ++ K +V Sbjct: 414 EKK-DKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVR 472 Query: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWE-------------------QEEKMQEQEEKM 148 K K K ++ ++ ++E+ E +E + E+ Sbjct: 473 KTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLT 532 Query: 149 WEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAG--GEAGEGSPQDNP 195 + EE RE+ + EQ + G + D G A +G+P P Sbjct: 533 QDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVP 581 Score = 36.6 bits (83), Expect = 0.020 Identities = 30/129 (23%), Positives = 65/129 (50%), Gaps = 12/129 (9%) Query: 71 WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQ 130 WE ++P K++ EQ + K+E + QQ +K E K+ E K + + ++ Sbjct: 1342 WED-KVPGLKDRTSEQKKEPEPKDEVL------QQKDKTLEHKEVVEPK----DTAIYQK 1390 Query: 131 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGS 190 +E + + E +++Q++ + EQ+ + EQ++ EQ++K ++K + + E + Sbjct: 1391 DEALHVKNEAVKQQDKAL-EQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKI 1449 Query: 191 PQDNPTAQE 199 P++ A E Sbjct: 1450 PEEKDKALE 1458 Score = 36.6 bits (83), Expect = 0.020 Identities = 37/161 (22%), Positives = 61/161 (37%), Gaps = 27/161 (16%) Query: 4 EERMREREKKMREEEEMMREQE-----EKMQEQEEKMREQEEKMW---------EQEEKM 49 EE+ E+ K M E+ E + E+ E+ QE + REQEEK W ++ Sbjct: 1597 EEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPT 1656 Query: 50 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM 109 +E+ ++ WE PEQ + W E + + + W+++ Sbjct: 1657 REEPAGEQKELAPAWEDTS--------PEQDNRYWRGRE-----DVALEQDTYWRELSCE 1703 Query: 110 REKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE 150 R+ E Q E+ E + E EQE + E Sbjct: 1704 RKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLRE 1744 Score = 35.8 bits (81), Expect = 0.033 Identities = 28/122 (22%), Positives = 59/122 (48%), Gaps = 15/122 (12%) Query: 75 RLPEQKEKMWEQDERLRE---KEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQE 131 +L +++E + E + R KE E+K + EK EK E E E ++ ++ Sbjct: 333 KLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEK 392 Query: 132 EMMWEQEEKMQEQEEKMWEQEEKMREQEEKM------------REQEEKMQGQEEKMRDV 179 + + + + +EK+ + EEK ++++++ R++E+K +EEK +D Sbjct: 393 RKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDT 452 Query: 180 EP 181 +P Sbjct: 453 KP 454 Score = 29.3 bits (64), Expect = 3.1 Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 10/147 (6%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMRE---QEEKMWEQEEKMQEQEEKMWEQ 59 EEE+ EKK RE E + ++ E +E E +++E ++ ++ E EE EE+ Sbjct: 617 EEEKDTWEEKKQREAER-LPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEEEDAT 675 Query: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLR----EKEERMREQKMWQQVEKMREKKKT 115 + + + Q+ + P +E ++ L+ EKE + + Sbjct: 676 KAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYI 735 Query: 116 QEEKMQEQEEKMQ--EQEEMMWEQEEK 140 Q+E + E Q EE+ E EE+ Sbjct: 736 QDETIPGYSETEQTISDEEIHDEPEER 762 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 91.3 bits (225), Expect = 7e-19 Identities = 48/177 (27%), Positives = 112/177 (63%), Gaps = 4/177 (2%) Query: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 RE ER +ER ++ + + E +E++ + ++E+K R++ E+ E+E K +E+E++ E+ E Sbjct: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91 Query: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVE-KMREKKKTQEEKM 120 K + K ++++ E+K++ + ++ +E++ER RE K ++ + K R KKK ++E+ Sbjct: 92 K---ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148 Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 +E+E +E++ ++EE+ +++E E++++ +E + R++E K + +++K R Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKER 205 Score = 90.5 bits (223), Expect = 1e-18 Identities = 56/181 (30%), Positives = 120/181 (66%), Gaps = 12/181 (6%) Query: 2 REEERMREREKKMRE-EEEMMREQ---EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 57 R++ER REREK+ RE E+E RE+ E+K +++ E+ +E+E K E+E++ +E+ EK Sbjct: 36 RKKER-REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK-- 92 Query: 58 EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE 117 + K ++++K +QR +++K E+ ER RE ++R RE+K ++ +K R K++ +E Sbjct: 93 -ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR-RERKRKKRRKKKRRKERKRE 150 Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 ++ ++E K +++++ E+ EK +E+ K ++E + +E+ E+ +E++++ + ++E+ + Sbjct: 151 KERGKRERKRKKRKK---EEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207 Query: 178 D 178 D Sbjct: 208 D 208 Score = 74.7 bits (182), Expect = 7e-14 Identities = 43/169 (25%), Positives = 108/169 (63%), Gaps = 8/169 (4%) Query: 17 EEEMMREQEEKMQEQEEKMREQEEK--MWEQEEKMQEQEEKMWEQEEKMWEQE----EKM 70 + E R++E + +E+ ++ RE+E K ++E+K +++ E+ E+E K E+E E+ Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90 Query: 71 WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM-REKKKTQEEKMQEQEEKMQE 129 +++R ++++K E+ +R R + ++ +E+K ++ K RE+K+ + K + ++E+ +E Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150 Query: 130 QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178 +E E++ K +++EE+ ++ E+ R++ +K RE++E+ + ++E+ ++ Sbjct: 151 KERGKRERKRKKRKKEERE-KKRERNRKERKKERERKERRERKKERKKE 198 Score = 58.2 bits (139), Expect = 6e-09 Identities = 31/131 (23%), Positives = 77/131 (58%), Gaps = 8/131 (6%) Query: 58 EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE 117 E E K +E + +++R E+K + +++++ R+K ER +E++ K +E++K ++ Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERE-----RKRKEREKQRK 87 Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177 E+ +++ K +++++ ++E K + + E+ ++E K RE+E K R + ++ + +++K R Sbjct: 88 ERREKERRKRKKEKK---KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144 Query: 178 DVEPAGGEAGE 188 E G+ Sbjct: 145 KERKREKERGK 155 Score = 43.9 bits (102), Expect = 1e-04 Identities = 23/80 (28%), Positives = 49/80 (61%), Gaps = 1/80 (1%) Query: 105 QVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK-MR 163 Q E R+K++ + EK + + EK +++E E++++ + + K E++ K RE++ K R Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90 Query: 164 EQEEKMQGQEEKMRDVEPAG 183 E+E + + +E+K R+ + G Sbjct: 91 EKERRKRKKEKKKRERKQRG 110 Score = 36.2 bits (82), Expect = 0.026 Identities = 15/72 (20%), Positives = 43/72 (59%) Query: 106 VEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 165 + K +++++ +K + + EK + + E ++E +E++++ + K RE++ K RE+ Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84 Query: 166 EEKMQGQEEKMR 177 + K + ++E+ + Sbjct: 85 QRKERREKERRK 96 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 90.9 bits (224), Expect = 9e-19 Identities = 50/173 (28%), Positives = 110/173 (63%), Gaps = 8/173 (4%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE----KMWEQEEKMQEQEEKMWE 58 +E+ + +E+++ EE+ + +KM+E E + +++EE + +QEE+ + +E + + Sbjct: 607 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK 666 Query: 59 QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEER---MREQKMWQQVEKMREKKKT 115 ++E+ E+ K E +RL EQ+E+ + ER RE+E R REQ+ +Q ++ E+++ Sbjct: 667 KKEEEQERLRKAAEAKRLAEQREQERREQER-REQERREQERREQERREQERQLAEQERR 725 Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168 +E++ + E ++QE+E+ + Q+E++Q + E+ ++EE+ R E +++E++EK Sbjct: 726 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 778 Score = 88.6 bits (218), Expect = 4e-18 Identities = 57/196 (29%), Positives = 115/196 (58%), Gaps = 20/196 (10%) Query: 3 EEERMREREKKMREEEEMMREQ---EEKMQEQEEKMREQEEKMW------EQEEKMQEQE 53 E+ER R + +EE E +R Q E+K + EE ++EE++ E+ E+M+E++ Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 595 Query: 54 EKMWEQEEKMWEQEEKMWEQQRLPEQK-------EKMWEQDERLREKEERMREQKMWQQV 106 +K EQ+ +++ + +++RL E+K +KM E + R +++EE R + + Q+ Sbjct: 596 KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE 655 Query: 107 EKMREKKKTQEEKMQEQEE--KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164 E+ R ++ Q++K +EQE K E + + ++E++ +EQE + EQE + +E+ E+ R Sbjct: 656 EERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERR--EQERREQERREQERR 713 Query: 165 QEEKMQGQEEKMRDVE 180 ++E+ ++E+ R+ E Sbjct: 714 EQERQLAEQERRREQE 729 Score = 86.3 bits (212), Expect = 2e-17 Identities = 56/197 (28%), Positives = 116/197 (58%), Gaps = 25/197 (12%) Query: 1 MREEERMR------EREKKMREEEEMMREQ------EEKMQEQEEKMREQEEKMWEQEEK 48 ++ EER+R ER ++M+EE++ EQ E+ + +EE++ E++ K +K Sbjct: 572 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK 631 Query: 49 MQEQEEKMWEQEEK-----MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW 103 M+E E + ++EE + ++EE+ Q+ L ++KE E+ ERLR+ E R + Sbjct: 632 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE---EEQERLRKAAEAKRLAEQR 688 Query: 104 QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ----EEKMWEQEEKMREQE 159 +Q + +E+++ + + + +E++ +EQE + EQE + +++ E ++ E+E+ +R Q+ Sbjct: 689 EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 748 Query: 160 EKM-REQEEKMQGQEEK 175 E++ RE EEK + +E++ Sbjct: 749 EQLQRELEEKKKKEEQQ 765 Score = 81.6 bits (200), Expect = 5e-16 Identities = 53/189 (28%), Positives = 110/189 (58%), Gaps = 14/189 (7%) Query: 1 MREEERMREREKKMREEEEM---MREQEEKMQEQEEKMREQEEKMWEQEEKMQE-QEEKM 56 + E++R R E K++ EE + ++ +E Q +EEK ++ E+K + +EK ++ +EE++ Sbjct: 559 VEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERL 618 Query: 57 WEQEEKMWEQEEKMWEQQRLPEQKEK----MWEQDERLREKEERMREQKMWQQVEKMR-- 110 E++ K +KM E + +Q+E+ W Q E + + + ++K ++ E++R Sbjct: 619 AEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKA 678 Query: 111 -EKKKTQEEKMQE-QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168 E K+ E++ QE +E++ +EQE E+ E+ + ++E+ ++E+ REQE E+E Sbjct: 679 AEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERE-- 736 Query: 169 MQGQEEKMR 177 +Q +E+ +R Sbjct: 737 LQEREKALR 745 Score = 79.7 bits (195), Expect = 2e-15 Identities = 48/161 (29%), Positives = 98/161 (60%), Gaps = 14/161 (8%) Query: 1 MREEERMREREKKMREEEEMMREQEEK------MQEQEEKMREQE---EKMWEQEEKMQE 51 + EE+ ++ K EE E R+QEE+ +Q++EE+ R QE +K E++E++++ Sbjct: 618 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRK 677 Query: 52 QEE--KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM 109 E ++ EQ E+ ++E+ +++R E++E+ + ER ++ER REQ+ Q ++ Sbjct: 678 AAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAEREL 737 Query: 110 REKKKT---QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEK 147 +E++K Q+E++Q + E+ +++EE E ++QE++EK Sbjct: 738 QEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 778 Score = 34.3 bits (77), Expect = 0.097 Identities = 22/90 (24%), Positives = 53/90 (58%), Gaps = 11/90 (12%) Query: 100 QKMWQQVEKMREKKKTQEEKMQE-QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 158 +K Q++E +R K++ ++ + Q+ +E+K + EE+ ++EE++++ + RE+ Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQA--------RER 587 Query: 159 EEKMREQEEKMQGQEEKMRDVEPAGGEAGE 188 E+M+E+++K E+K ++ +A E Sbjct: 588 VEQMKEEKKKQ--IEQKFAQIDEKTEKAKE 615 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 90.9 bits (224), Expect = 9e-19 Identities = 50/173 (28%), Positives = 110/173 (63%), Gaps = 8/173 (4%) Query: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE----KMWEQEEKMQEQEEKMWE 58 +E+ + +E+++ EE+ + +KM+E E + +++EE + +QEE+ + +E + + Sbjct: 603 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK 662 Query: 59 QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEER---MREQKMWQQVEKMREKKKT 115 ++E+ E+ K E +RL EQ+E+ + ER RE+E R REQ+ +Q ++ E+++ Sbjct: 663 KKEEEQERLRKAAEAKRLAEQREQERREQER-REQERREQERREQERREQERQLAEQERR 721 Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168 +E++ + E ++QE+E+ + Q+E++Q + E+ ++EE+ R E +++E++EK Sbjct: 722 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 774 Score = 89.4 bits (220), Expect = 3e-18 Identities = 57/197 (28%), Positives = 116/197 (58%), Gaps = 20/197 (10%) Query: 2 REEERMREREKKMREEEEMMREQ---EEKMQEQEEKMREQEEKMW------EQEEKMQEQ 52 +E+ER R + +EE E +R Q E+K + EE ++EE++ E+ E+M+E+ Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590 Query: 53 EEKMWEQEEKMWEQEEKMWEQQRLPEQK-------EKMWEQDERLREKEERMREQKMWQQ 105 ++K EQ+ +++ + +++RL E+K +KM E + R +++EE R + + Q+ Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 650 Query: 106 VEKMREKKKTQEEKMQEQEE--KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 163 E+ R ++ Q++K +EQE K E + + ++E++ +EQE + EQE + +E+ E+ R Sbjct: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERR--EQERREQERREQER 708 Query: 164 EQEEKMQGQEEKMRDVE 180 ++E+ ++E+ R+ E Sbjct: 709 REQERQLAEQERRREQE 725 Score = 86.3 bits (212), Expect = 2e-17 Identities = 56/197 (28%), Positives = 116/197 (58%), Gaps = 25/197 (12%) Query: 1 MREEERMR------EREKKMREEEEMMREQ------EEKMQEQEEKMREQEEKMWEQEEK 48 ++ EER+R ER ++M+EE++ EQ E+ + +EE++ E++ K +K Sbjct: 568 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK 627 Query: 49 MQEQEEKMWEQEEK-----MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW 103 M+E E + ++EE + ++EE+ Q+ L ++KE E+ ERLR+ E R + Sbjct: 628 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE---EEQERLRKAAEAKRLAEQR 684 Query: 104 QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ----EEKMWEQEEKMREQE 159 +Q + +E+++ + + + +E++ +EQE + EQE + +++ E ++ E+E+ +R Q+ Sbjct: 685 EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 744 Query: 160 EKM-REQEEKMQGQEEK 175 E++ RE EEK + +E++ Sbjct: 745 EQLQRELEEKKKKEEQQ 761 Score = 81.6 bits (200), Expect = 5e-16 Identities = 53/189 (28%), Positives = 110/189 (58%), Gaps = 14/189 (7%) Query: 1 MREEERMREREKKMREEEEM---MREQEEKMQEQEEKMREQEEKMWEQEEKMQE-QEEKM 56 + E++R R E K++ EE + ++ +E Q +EEK ++ E+K + +EK ++ +EE++ Sbjct: 555 VEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERL 614 Query: 57 WEQEEKMWEQEEKMWEQQRLPEQKEK----MWEQDERLREKEERMREQKMWQQVEKMR-- 110 E++ K +KM E + +Q+E+ W Q E + + + ++K ++ E++R Sbjct: 615 AEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKA 674 Query: 111 -EKKKTQEEKMQE-QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168 E K+ E++ QE +E++ +EQE E+ E+ + ++E+ ++E+ REQE E+E Sbjct: 675 AEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERE-- 732 Query: 169 MQGQEEKMR 177 +Q +E+ +R Sbjct: 733 LQEREKALR 741 Score = 79.7 bits (195), Expect = 2e-15 Identities = 48/161 (29%), Positives = 98/161 (60%), Gaps = 14/161 (8%) Query: 1 MREEERMREREKKMREEEEMMREQEEK------MQEQEEKMREQE---EKMWEQEEKMQE 51 + EE+ ++ K EE E R+QEE+ +Q++EE+ R QE +K E++E++++ Sbjct: 614 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRK 673 Query: 52 QEE--KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM 109 E ++ EQ E+ ++E+ +++R E++E+ + ER ++ER REQ+ Q ++ Sbjct: 674 AAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAEREL 733 Query: 110 REKKKT---QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEK 147 +E++K Q+E++Q + E+ +++EE E ++QE++EK Sbjct: 734 QEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 774 Score = 63.5 bits (153), Expect = 1e-10 Identities = 53/218 (24%), Positives = 117/218 (53%), Gaps = 38/218 (17%) Query: 14 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 73 ++ + + +EK +++ E +R +EE EQ + + +E+K EE ++EE++ Sbjct: 520 IKRNTPLRMDPKEKERQRLENLRRKEEA--EQLRRQKVEEDKRRRLEEVKLKREERL--- 574 Query: 74 QRLPEQKEKMWEQDERLREKEERMREQKMWQ---QVEKMREK--------KKTQEEKMQE 122 +++ + +E++ E+++E++++ EQK Q + EK +E+ KK +KM+E Sbjct: 575 RKVLQARERV----EQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 630 Query: 123 QEEKMQEQEE---MMW--EQEEKMQEQE---EKMWEQEEKMR----------EQEEKMRE 164 E + +++EE + W ++EE+ + QE +K E++E++R ++E++ RE Sbjct: 631 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 690 Query: 165 QEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEIMQ 202 QE + Q + E+ R + + + + Q+ QE +Q Sbjct: 691 QERREQERREQERREQERREQERQLAEQERRREQERLQ 728 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.304 0.120 0.332 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,970,555 Number of Sequences: 37866 Number of extensions: 830846 Number of successful extensions: 105961 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1991 Number of HSP's successfully gapped in prelim test: 938 Number of HSP's that attempted gapping in prelim test: 7475 Number of HSP's gapped (non-prelim): 31384 length of query: 238 length of database: 18,247,518 effective HSP length: 99 effective length of query: 139 effective length of database: 14,498,784 effective search space: 2015330976 effective search space used: 2015330976 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.9 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.