Guide to the Human Genome
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Search of human proteins with 239752551

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
         (238 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]           491   e-139
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...   376   e-104
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...   281   5e-76
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...   226   1e-59
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...   226   2e-59
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...   226   2e-59
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...   222   2e-58
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...   218   5e-57
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...   216   2e-56
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...   202   3e-52
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]           172   2e-43
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap...   140   1e-33
gi|148746195 trichohyalin [Homo sapiens]                              123   2e-28
gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub...   113   2e-25
gi|154937324 hypothetical protein LOC440295 [Homo sapiens]            113   2e-25
gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap...   112   2e-25
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi...   104   6e-23
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap...   104   8e-23
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C...   104   8e-23
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi...   103   1e-22
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]           100   2e-21
gi|221219020 NYD-SP11 protein [Homo sapiens]                           99   4e-21
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    95   6e-20
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    95   6e-20
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    95   6e-20
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    95   6e-20
gi|95147555 microtubule-associated protein 1A [Homo sapiens]           94   8e-20
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            91   7e-19
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    91   9e-19
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    91   9e-19

>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 238

 Score =  491 bits (1265), Expect = e-139
 Identities = 238/238 (100%), Positives = 238/238 (100%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
           MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE
Sbjct: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60

Query: 61  EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
           EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM
Sbjct: 61  EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120

Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
           QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE
Sbjct: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180

Query: 181 PAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI 238
           PAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI
Sbjct: 181 PAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI 238


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score =  376 bits (965), Expect = e-104
 Identities = 201/274 (73%), Positives = 222/274 (81%), Gaps = 37/274 (13%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
           MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE
Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615

Query: 61  EKMWEQEEK---------MWEQ-QRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEK 108
           EKMWEQEE+         MWEQ +++ EQ+EKMWEQ+E++RE+EE+MREQ  KM  Q EK
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 675

Query: 109 MR---EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 165
           MR   EK + QEEKM+EQEEKM+ QEE MW QEEKM  QEEKMW QEE MRE+EE++R+Q
Sbjct: 676 MREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE-MREKEERIRDQ 734

Query: 166 EEKMQGQ----EEKMRD-----------------VEPAGGEAGEGSPQDNPTAQEIMQLF 204
           +EKMQ +    EE+  +                 VEPAGGEAGEGSPQDNPTAQEIMQLF
Sbjct: 735 KEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEGSPQDNPTAQEIMQLF 794

Query: 205 CGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI 238
           CGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI
Sbjct: 795 CGMKNAQQCPGLGSTSCIPFFYRGDKRKMKIINI 828



 Score =  259 bits (662), Expect = 1e-69
 Identities = 157/293 (53%), Positives = 171/293 (58%), Gaps = 113/293 (38%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ------------EEK 48
           M+EEER+REREKKMREEEE MREQEEKMQ+QEE M EQEEK W+Q            +EK
Sbjct: 388 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 447

Query: 49  MQEQEEKMWEQEEK------MWEQEEKMWEQQRLPE---------------------QKE 81
           MQEQEEK+WEQEEK      MW QE+KMW Q+++ E                     Q+E
Sbjct: 448 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 507

Query: 82  KMWEQDERLREKEERMREQ-KMWQQVEKMREKKKT------------------------- 115
           +MWEQDERLREKEERMREQ KMWQQ EKMRE+KKT                         
Sbjct: 508 RMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREK 567

Query: 116 -----------QEEKMQEQEE-------------------------------------KM 127
                      QEEKMQEQEE                                     KM
Sbjct: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627

Query: 128 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
           QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR+ E
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680



 Score =  243 bits (621), Expect = 8e-65
 Identities = 131/221 (59%), Positives = 166/221 (75%), Gaps = 43/221 (19%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+E+R+RE+EK++RE+E+ +REQ+ K++EQEE+M+EQEEKMWEQEEKM+EQEEKMW QEE
Sbjct: 280 RQEKRLREQEKELREQEKELREQK-KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338

Query: 62  KMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMRE-------- 111
           ++WEQE++M EQ Q++ +Q+E+MWEQDERLREKEERMREQ KMW+Q EKM+E        
Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRERE 398

Query: 112 -KKKTQEEKMQEQEEKMQEQEEMMWEQE-------------------EKMQEQEEKMWEQ 151
            K + +EE M+EQEEKMQ+QEE MWEQE                   EKMQEQEEK+WEQ
Sbjct: 399 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 458

Query: 152 EEKMREQE------------EKMREQEEKMQGQEEKMRDVE 180
           EEK+R+QE            EKMREQE++M  QEEKMRD E
Sbjct: 459 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 499



 Score =  226 bits (576), Expect = 1e-59
 Identities = 123/193 (63%), Positives = 157/193 (81%), Gaps = 18/193 (9%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMRE------QEEKMWEQEEKMQEQE--- 53
           +EERM E+++++RE+EE MREQ+ KM +QEEKMRE      QE+K W+QEEKM+E+E   
Sbjct: 505 QEERMWEQDERLREKEERMREQK-KMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563

Query: 54  ---EKMWEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERM--REQKMWQQVE 107
              +KM E+EE M EQEEKM EQ+ ++ EQ+EKMWEQ+E+++E+EE+M  +E+KMW+Q E
Sbjct: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 623

Query: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167
           +  +K + QEE M EQEEKMQEQEE MWEQEEKM+EQEEKM EQEEKM+ QEEKMREQEE
Sbjct: 624 E--DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681

Query: 168 KMQGQEEKMRDVE 180
           KMQGQEEKMR+ E
Sbjct: 682 KMQGQEEKMREQE 694



 Score =  223 bits (567), Expect = 1e-58
 Identities = 122/180 (67%), Positives = 153/180 (85%), Gaps = 11/180 (6%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           ++EE+MRE EKK +E+E+   +QEEKM+E EE+MRE+E+KM E+EE M+EQEEKM EQEE
Sbjct: 531 QQEEKMRE-EKKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEE 588

Query: 62  KMWEQEEKMWEQ-QRLPEQKEKMWEQDERL--REKEERMREQK--MWQQVEKMREKKKTQ 116
           KM EQEEKMWEQ +++ EQ+EKMWEQ+E++  +E+E++M+EQ+  MW+Q EKM+E    Q
Sbjct: 589 KMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQE----Q 644

Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
           EEKM EQEEKM+EQEE M EQEEKMQ QEEKM EQEEKM+ QEEKMREQEEKM+GQEEKM
Sbjct: 645 EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKM 704



 Score =  217 bits (552), Expect = 8e-57
 Identities = 122/228 (53%), Positives = 161/228 (70%), Gaps = 51/228 (22%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE------KMWEQEEKMQE---- 51
           R+EER+ E+EK+MRE+E+ MR+QEE+M EQ+E++RE+EE      KMWEQEEKMQE    
Sbjct: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394

Query: 52  ----------------QEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMW------EQDER 89
                           QEEKM +QEE MWEQEEK W+QQRLPEQKEK+W      EQ+E+
Sbjct: 395 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454

Query: 90  LREKEERMREQ--------KMWQQVEKMREKKK---TQEEKMQEQEEKMQEQEEMMWEQE 138
           + E+EE++R+Q        KMW+Q EKMRE++     QEEKM++QE+KM +QEE MWEQ+
Sbjct: 455 IWEQEEKIRDQEEMWGQEKKMWRQ-EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD 513

Query: 139 EKMQEQEE------KMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
           E+++E+EE      KMW+QEEKMRE E+K +EQE+K   QEEKMR+ E
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMRE-EKKTQEQEKKTWDQEEKMREEE 560



 Score =  177 bits (449), Expect = 7e-45
 Identities = 102/194 (52%), Positives = 142/194 (73%), Gaps = 25/194 (12%)

Query: 1   MREEERMREREKKMREE------EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 54
           ++E +R  ER K +  +      +E M  QEE+++EQE+K+R+QEEKMW QEE+++EQE 
Sbjct: 210 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEG 269

Query: 55  KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERL------REKEERMREQ--KMWQQV 106
           KM EQEEKM  QE+      RL EQ++++ EQ++ L      RE+EE+M+EQ  KMW+Q 
Sbjct: 270 KMREQEEKMRRQEK------RLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323

Query: 107 EKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 166
           EKMRE    QEEKM  QEE++ EQE+ M EQE+KM++QEE+MWEQ+E++RE+EE+MREQ 
Sbjct: 324 EKMRE----QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ- 378

Query: 167 EKMQGQEEKMRDVE 180
           EKM  QEEKM++ E
Sbjct: 379 EKMWEQEEKMQEEE 392



 Score =  157 bits (397), Expect = 8e-39
 Identities = 87/180 (48%), Positives = 130/180 (72%), Gaps = 14/180 (7%)

Query: 9   EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 68
           E +KK  E +E +R  E +  E +  ++E + K+ E+ + +  Q +    QEE MW QEE
Sbjct: 184 ELKKKNAELQEKLRLAESEKSEIQLNVKELKRKL-ERAKFLLPQVQTNTLQEE-MWRQEE 241

Query: 69  KMWEQQR-LPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKK---------TQ 116
           ++ EQ++ + +Q+EKMW Q+ERLRE+E +MREQ  KM +Q +++RE++K          +
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301

Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
           ++K++EQEE+MQEQEE MWEQEEKM+EQEEKMW QEE++ EQE++MREQE+KM+ QEE+M
Sbjct: 302 QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 361



 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 48/119 (40%), Positives = 85/119 (71%), Gaps = 1/119 (0%)

Query: 61  EKMWEQEEKMWEQQRLPE-QKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119
           E++ ++  ++ E+ RL E +K ++    + L+ K ER +      Q   ++E+   QEE+
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242

Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
           ++EQE+K+++QEE MW QEE+++EQE KM EQEEKMR QE+++REQE++++ QE+++R+
Sbjct: 243 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301



 Score = 80.9 bits (198), Expect = 9e-16
 Identities = 47/128 (36%), Positives = 72/128 (56%), Gaps = 7/128 (5%)

Query: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119
           EE   E++    E  R     E++ +++  L+EK      +K   Q+     K+K +  K
Sbjct: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK 221

Query: 120 MQEQEEKMQEQEEMMWEQEEKMQE-------QEEKMWEQEEKMREQEEKMREQEEKMQGQ 172
               + +    +E MW QEE+++E       QEEKMW QEE++REQE KMREQEEKM+ Q
Sbjct: 222 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQ 281

Query: 173 EEKMRDVE 180
           E+++R+ E
Sbjct: 282 EKRLREQE 289



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 32/117 (27%), Positives = 63/117 (53%), Gaps = 1/117 (0%)

Query: 64  WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
           W ++   + ++   E+     E        EE  ++    Q+  ++ E +K++ +   ++
Sbjct: 153 WHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKE 212

Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
            ++  E+ + +  Q +    QEE    QEE++REQE+K+R+QEEKM  QEE++R+ E
Sbjct: 213 LKRKLERAKFLLPQVQTNTLQEEMWR-QEEELREQEKKIRKQEEKMWRQEERLREQE 268


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score =  281 bits (718), Expect = 5e-76
 Identities = 154/238 (64%), Positives = 170/238 (71%), Gaps = 59/238 (24%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
           MREEERMREREKKMREEEEMMREQEEKMQEQEEKM+EQEEKMWEQEEKMQEQEEKMWEQE
Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644

Query: 61  EKMWEQEEKMWEQQRLPEQKEKMWE-----QDERLREKEERM------------REQKMW 103
           EKMWEQEEKMWEQQRLPEQKEK+WE     + E+++E+EE++            +E+K W
Sbjct: 645 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTW 704

Query: 104 QQVEKMREKK----------------KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEK 147
            Q EKMRE++                + QEEKMQEQEEKMQEQEE MWEQEEKM EQEEK
Sbjct: 705 DQ-EKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763

Query: 148 M-------------------------WEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
           M                         WEQEEKMR+QEEKMR QEEKM+GQEEKMR  E
Sbjct: 764 MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821



 Score =  248 bits (633), Expect = 3e-66
 Identities = 134/185 (72%), Positives = 155/185 (83%), Gaps = 11/185 (5%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
           MREEE MREREKKMREEEEMMREQEEKMQEQEEKM+EQEE+MWEQEEKM EQEEKMWEQ 
Sbjct: 709 MREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQ- 767

Query: 61  EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMR--EQKMWQQVEKMR---EKKKT 115
           +++ EQ+EK+WE +++ EQ EK+WEQ+E++R++EE+MR  E+KM  Q EKMR   EK   
Sbjct: 768 QRLPEQKEKLWEHEKMQEQ-EKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWG 826

Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQE----QEEKMWEQEEKMREQEEKMREQEEKMQG 171
           QEEKM  QEEKM  QEE MW QEEKM+E    QEEKM EQEEKMR QEEKMREQEEKM+G
Sbjct: 827 QEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRG 886

Query: 172 QEEKM 176
           QEEK+
Sbjct: 887 QEEKI 891



 Score =  245 bits (625), Expect = 3e-65
 Identities = 128/209 (61%), Positives = 159/209 (76%), Gaps = 33/209 (15%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE------------EK 48
           M+EEER+REREKKMREEEE MREQEEKMQ+QEE M EQEEK W+Q+            EK
Sbjct: 446 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 505

Query: 49  MQEQEEKMWEQEEK------MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERM----- 97
           MQEQEEK+WEQEEK      MW QE+KMW Q+++ EQ+++MWEQ+E++R++E++M     
Sbjct: 506 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 565

Query: 98  --------REQKMWQQVEKMREKK--KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEK 147
                   +E+K W Q EKMRE++  + +E+KM+E+EE M+EQEE M EQEEKMQEQEEK
Sbjct: 566 RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEK 625

Query: 148 MWEQEEKMREQEEKMREQEEKMQGQEEKM 176
           MWEQEEKM+EQEEKM EQEEKM  QEEKM
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654



 Score =  244 bits (622), Expect = 6e-65
 Identities = 133/227 (58%), Positives = 172/227 (75%), Gaps = 30/227 (13%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+E+R+RE+EK++RE+E+ +REQ+E ++EQEE+M+EQEEKMWEQEEKM+EQEEKMW QEE
Sbjct: 318 RQEKRLREQEKELREQEKELREQKE-LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 376

Query: 62  KMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMREKKK----- 114
           ++WEQE++M EQ Q++ +Q+E+MWEQDERLREKEERMREQ KMW+QVEKMRE+KK     
Sbjct: 377 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQE 436

Query: 115 ----TQEEKMQEQ------EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ------ 158
                QEEKMQE+      E+KM+E+EE M EQEEKMQ+QEE MWEQEEK  +Q      
Sbjct: 437 KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496

Query: 159 ------EEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199
                 +EKM+EQEEK+  QEEK+RD E   G+  +   Q+    QE
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543



 Score =  241 bits (614), Expect = 5e-64
 Identities = 127/189 (67%), Positives = 148/189 (78%), Gaps = 12/189 (6%)

Query: 4   EERMREREKK-----MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 58
           E++ +E+EKK        EEE MRE+E+KM+E+EE MREQEEKM EQEEKMQEQEE+MWE
Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWE 752

Query: 59  QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR---EKKKT 115
           QEEKMWEQEEKMWEQQRLPEQKEK+WE ++   +++   +E+KM  Q EKMR   EK + 
Sbjct: 753 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRG 812

Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE----QEEKMREQEEKMQG 171
           QEEKM+ QEEKM  QEE MW QEEKM  QEEKMW QEEKM E    QEEKMREQEEKM+G
Sbjct: 813 QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRG 872

Query: 172 QEEKMRDVE 180
           QEEKMR+ E
Sbjct: 873 QEEKMREQE 881



 Score =  236 bits (603), Expect = 1e-62
 Identities = 132/193 (68%), Positives = 151/193 (78%), Gaps = 15/193 (7%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           +E+E+    ++KMREEE M RE+E+KM+E+EE MREQEEKM EQEEKMQEQEE+MWEQEE
Sbjct: 697 QEQEKKTWDQEKMREEESM-REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE 755

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQD-----ERLREKEERMREQ--KMWQQVEKMR---E 111
           KMWEQEEKMWEQQRLPEQKEK+WE +     E++ E+EE+MR+Q  KM  Q EKMR   E
Sbjct: 756 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEE 815

Query: 112 KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE----QEEKMREQEEKMREQEE 167
           K + QEEKM  QEEKM  QEE MW QEEKM  QEEKM E    QEEKMREQEEKMR QEE
Sbjct: 816 KMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEE 875

Query: 168 KMQGQEEKMRDVE 180
           KM+ QEEKMR  E
Sbjct: 876 KMREQEEKMRGQE 888



 Score =  223 bits (567), Expect = 1e-58
 Identities = 118/204 (57%), Positives = 159/204 (77%), Gaps = 30/204 (14%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
           MREE++M+E+EKK R++EE M+E EE+++E+E+KMRE+EE M EQEEKMQ+QEE MWEQE
Sbjct: 426 MREEKKMQEQEKKTRDQEEKMQE-EERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484

Query: 61  EKMW------EQEEKMWEQQRLPEQKEKMWEQDERLREKEERM-REQKMWQQVEKMREKK 113
           EK W      EQ+EK+WEQ+++ EQ+EK+WEQ+E++R++EE   +E+KMW+Q EKMRE  
Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ-EKMRE-- 541

Query: 114 KTQEEKMQEQEEKMQEQEEMMWEQEEKM----QEQEEKMWEQEEK-------------MR 156
             QE++M EQEEKM++QE+ MW+QEE+M    QEQE+K W+QEEK             MR
Sbjct: 542 --QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599

Query: 157 EQEEKMREQEEKMQGQEEKMRDVE 180
           E+EE MREQEEKMQ QEEKM++ E
Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQE 623



 Score =  211 bits (538), Expect = 3e-55
 Identities = 115/222 (51%), Positives = 158/222 (71%), Gaps = 43/222 (19%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
           +RE++ +RE+E++M+E+EE M EQEEKM+EQEEKM  QEE++WEQE++M+EQE+KM +QE
Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396

Query: 61  EKMWEQEEKMWEQQRLPEQKEKMWEQDERLR--------EKEERMREQKMWQQVEKMREK 112
           E+MWEQ+E++ E++    ++EKMWEQ E++R        EK+ R +E+KM Q+ E++RE+
Sbjct: 397 ERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKM-QEEERIRER 455

Query: 113 KK---TQEEKMQEQEEKMQEQEEMMWEQE-------------------EKMQEQEEKMWE 150
           +K    +EE M+EQEEKMQ+QEE MWEQE                   EKMQEQEEK+WE
Sbjct: 456 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 515

Query: 151 QEEKMREQE------------EKMREQEEKMQGQEEKMRDVE 180
           QEEK+R+QE            EKMREQE++M  QEEKMRD E
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 557



 Score =  203 bits (517), Expect = 9e-53
 Identities = 117/216 (54%), Positives = 157/216 (72%), Gaps = 37/216 (17%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKM----REQEEKMWEQEEKMQEQE--- 53
           M  +E+MRE+E +M E+EE MR+QE+KM +QEE+M    +EQE+K W+QEEKM+E+E   
Sbjct: 533 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMR 592

Query: 54  ---EKMWEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERM--REQKMWQQVE 107
              +KM E+EE M EQEEKM EQ+ ++ EQ+EKMWEQ+E+++E+EE+M  +E+KMW+Q E
Sbjct: 593 EREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 652

Query: 108 KMREKKKTQE--------EKMQEQEEKMQEQEEMMWEQ---EEKMQEQEEKMWEQ----- 151
           KM E+++  E        EKMQEQE KMQEQEE +WEQ   E+K QEQE+K W+Q     
Sbjct: 653 KMWEQQRLPEQKEKLWEHEKMQEQE-KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE 711

Query: 152 -------EEKMREQEEKMREQEEKMQGQEEKMRDVE 180
                  E+KMRE+EE MREQEEKMQ QEEKM++ E
Sbjct: 712 EESMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 747



 Score =  181 bits (458), Expect = 6e-46
 Identities = 104/206 (50%), Positives = 144/206 (69%), Gaps = 36/206 (17%)

Query: 1   MREEERMREREKKMREE------EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 54
           ++E +R  ER K +  +      +E M  QEE+++EQE+K+R+QEEKMW QEE+++EQE 
Sbjct: 248 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEG 307

Query: 55  KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERL------REKEERMREQ--KMWQQV 106
           KM EQEEKMW QE+      RL EQ++++ EQ++ L      RE+EE+M+EQ  KMW+Q 
Sbjct: 308 KMREQEEKMWRQEK------RLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQE 361

Query: 107 EKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ- 165
           EKMRE    QEEKM  QEE++ EQE+ M EQE+KM++QEE+MWEQ+E++RE+EE+MREQ 
Sbjct: 362 EKMRE----QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 417

Query: 166 -----------EEKMQGQEEKMRDVE 180
                      E+KMQ QE+K RD E
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQE 443



 Score =  170 bits (431), Expect = 9e-43
 Identities = 90/181 (49%), Positives = 131/181 (72%), Gaps = 13/181 (7%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           + E ++  +E K + E       + +    +E+M  QEE++ EQE+K+++QEEKMW QEE
Sbjct: 241 KSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEE 300

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK--KTQEEK 119
           ++ EQE KM       EQ+EKMW Q++RLRE+E+ +REQ+     +++RE+K  + QEE+
Sbjct: 301 RLREQEGKM------REQEEKMWRQEKRLREQEKELREQE-----KELREQKELREQEEQ 349

Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDV 179
           MQEQEEKM EQEE M EQEEKM  QEE++WEQE++MREQE+KMR+QEE+M  Q+E++R+ 
Sbjct: 350 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 409

Query: 180 E 180
           E
Sbjct: 410 E 410



 Score =  159 bits (401), Expect = 3e-39
 Identities = 81/185 (43%), Positives = 131/185 (70%), Gaps = 19/185 (10%)

Query: 5   ERMREREKKMREEEEMMREQEEKMQ--EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
           E ++++  +++E+  +   ++ ++Q   +E K + +  K    + +    +E+MW QEE+
Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 280

Query: 63  MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKK------ 114
           + EQE+K      + +Q+EKMW Q+ERLRE+E +MREQ  KMW+Q +++RE++K      
Sbjct: 281 LREQEKK------IRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQE 334

Query: 115 ---TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG 171
               ++++++EQEE+MQEQEE MWEQEEKM+EQEEKMW QEE++ EQE++MREQE+KM+ 
Sbjct: 335 KELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 394

Query: 172 QEEKM 176
           QEE+M
Sbjct: 395 QEERM 399



 Score = 99.8 bits (247), Expect = 2e-21
 Identities = 62/152 (40%), Positives = 90/152 (59%), Gaps = 25/152 (16%)

Query: 50  QEQEEKMWEQEEKM-WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEK 108
           +E ++K  E +EK+   + EK   Q  + E K K+      L + +    +++MW+Q E+
Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 280

Query: 109 MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEK-------------- 154
           +RE    QE+K+++QEEKM  QEE + EQE KM+EQEEKMW QE++              
Sbjct: 281 LRE----QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336

Query: 155 ------MREQEEKMREQEEKMQGQEEKMRDVE 180
                 +REQEE+M+EQEEKM  QEEKMR+ E
Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEEKMREQE 368



 Score = 79.3 bits (194), Expect = 3e-15
 Identities = 47/128 (36%), Positives = 71/128 (55%), Gaps = 7/128 (5%)

Query: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119
           EE   E++    E  R     E++ +++  L+EK      +K   Q+     K+K +  K
Sbjct: 200 EELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAK 259

Query: 120 MQEQEEKMQEQEEMMWEQEEKMQE-------QEEKMWEQEEKMREQEEKMREQEEKMQGQ 172
               + +    +E MW QEE+++E       QEEKMW QEE++REQE KMREQEEKM  Q
Sbjct: 260 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQ 319

Query: 173 EEKMRDVE 180
           E+++R+ E
Sbjct: 320 EKRLREQE 327


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score =  226 bits (577), Expect = 1e-59
 Identities = 116/188 (61%), Positives = 154/188 (81%), Gaps = 5/188 (2%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           ++EE+M  +E+K++E EE ++EQEEK++EQEEKMR QEE MWE+EEKM+ QEE MWE+EE
Sbjct: 285 QQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 344

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERM-REQKMWQQVEKMR---EKKKTQE 117
           K+ E EEKM EQ+++ EQ+EK  +++E++RE+E+R  +E KMW+Q EK+R   EK + QE
Sbjct: 345 KIRELEEKMHEQEKIREQEEKR-QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 403

Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
           E MQEQEEKM EQEE MWEQEE+MQEQEEKM  QEEK+REQE+K+REQEEK++ QEE M+
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 463

Query: 178 DVEPAGGE 185
           + E   GE
Sbjct: 464 EQEEKMGE 471



 Score =  224 bits (571), Expect = 5e-59
 Identities = 120/183 (65%), Positives = 154/183 (84%), Gaps = 6/183 (3%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+EE++RE+E+K+RE+EEMM+EQEEKM EQEEKM EQEE+M EQEEKM+ QEEK+ EQE+
Sbjct: 387 RQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK 446

Query: 62  KMWEQEEKMWEQQRL-PEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKT--- 115
           K+ EQEEK+ EQ+ +  EQ+EKM EQ+ ++ E+E +M+EQ  KM +Q EK+RE++K    
Sbjct: 447 KIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIRE 506

Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175
           QEEK++EQEE MQEQEE MWEQEEKM EQEEKM EQEEKMR QEEKMREQE +++ QEEK
Sbjct: 507 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566

Query: 176 MRD 178
           M++
Sbjct: 567 MQE 569



 Score =  221 bits (564), Expect = 3e-58
 Identities = 119/181 (65%), Positives = 149/181 (82%), Gaps = 7/181 (3%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
           +E +M  +E+K+RE+EE +REQEE MQEQEEKM EQEEKMWEQEE+MQEQEEKM  QEEK
Sbjct: 381 QEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEK 440

Query: 63  MWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEEK 119
           + EQE+K+ EQ+ ++ EQ+E M EQ+E++ E+E +M EQ  KM +Q EKMR     QEEK
Sbjct: 441 IREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR----QEEK 496

Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDV 179
           ++EQE+K++EQEE + EQEE MQEQEEKMWEQEEKM EQEEKM+EQEEKM+ QEEKMR+ 
Sbjct: 497 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQ 556

Query: 180 E 180
           E
Sbjct: 557 E 557



 Score =  207 bits (528), Expect = 5e-54
 Identities = 117/221 (52%), Positives = 156/221 (70%), Gaps = 26/221 (11%)

Query: 4   EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63
           EE+++E+E+K+RE+EE MR QEE M E+EEKMR QEE MWE+EEK++E EEKM EQE K+
Sbjct: 301 EEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KI 359

Query: 64  WEQEEKMWEQQRLPEQKE------KMWEQDERLREKEERMREQ----------------K 101
            EQEEK  E++++ EQ++      KMW Q+E++RE+EE++REQ                K
Sbjct: 360 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 419

Query: 102 MWQQVEKMR---EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 158
           MW+Q E+M+   EK + QEEK++EQE+K++EQEE + EQEE MQEQEEKM EQE KM EQ
Sbjct: 420 MWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQ 479

Query: 159 EEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199
           E KM+EQEEKM+ QEEK+R+ E    E  E   +     QE
Sbjct: 480 EAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 520



 Score =  182 bits (461), Expect = 3e-46
 Identities = 103/171 (60%), Positives = 129/171 (75%), Gaps = 12/171 (7%)

Query: 16  EEEEMM----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 71
           EE E+     ++QEEKM  QEEK++E+EEK+ EQEEK++EQEEKM  QEE MWE+EEKM 
Sbjct: 274 EENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMR 333

Query: 72  EQQRLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMREKKKTQE-EKMQEQEEKMQE 129
            Q+      E MWE++E++RE EE+M EQ K+ +Q EK +E++K +E EK QEQE KM  
Sbjct: 334 RQE------EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 387

Query: 130 QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
           QEE + EQEEK++EQEE M EQEEKM EQEEKM EQEE+MQ QEEKMR  E
Sbjct: 388 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQE 438



 Score =  136 bits (342), Expect = 2e-32
 Identities = 77/130 (59%), Positives = 100/130 (76%), Gaps = 16/130 (12%)

Query: 1   MREEER-MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
           +RE+E  M+E+E+KM E+E  M EQE KMQEQEEKMR QEEK+ EQE+K++EQEEK+ EQ
Sbjct: 455 IREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 514

Query: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119
           EE M EQEEKMWEQ+      EKM EQ+E+++E+EE+MR Q+     EKMRE    QE +
Sbjct: 515 EEMMQEQEEKMWEQE------EKMCEQEEKMQEQEEKMRRQE-----EKMRE----QEVR 559

Query: 120 MQEQEEKMQE 129
           +++QEEKMQE
Sbjct: 560 LRQQEEKMQE 569



 Score =  112 bits (281), Expect = 2e-25
 Identities = 66/205 (32%), Positives = 126/205 (61%), Gaps = 11/205 (5%)

Query: 9   EREKKMREEEEMMREQEEKMQE------QEEKMREQEEKMWEQEEKMQEQEEKMW---EQ 59
           +++K  R  EE+ +E++    E       +E+++E+  K+ E+ + ++ ++ ++    ++
Sbjct: 175 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 234

Query: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK-EERMREQKMWQQVEKMREKKK-TQE 117
            ++  E+ + +  QQ+L  + + + ++ + +  K + ++ E ++W ++ + +E+K   QE
Sbjct: 235 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 294

Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
           EK+QE+EEK+QEQEE + EQEEKM+ QEE MWE+EEKMR QEE M E+EEK++  EEKM 
Sbjct: 295 EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 354

Query: 178 DVEPAGGEAGEGSPQDNPTAQEIMQ 202
           + E    +  +   ++    QE  Q
Sbjct: 355 EQEKIREQEEKRQEEEKIREQEKRQ 379


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score =  226 bits (575), Expect = 2e-59
 Identities = 121/231 (52%), Positives = 162/231 (70%), Gaps = 34/231 (14%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+EE+M E+E+K+RE+E+ M  QEEK++EQEEK+REQEEKMW QEEK++EQ+EK+ EQEE
Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMR--------- 110
           +MW QEEK+ EQ+   +++EKMW Q++++RE++E++REQ  +MW+Q EK+R         
Sbjct: 389 EMWRQEEKIREQEE--KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ 446

Query: 111 ---------------EKKKTQEEKMQEQEEKMQEQEEMMW------EQEEKMQEQEEKMW 149
                          EK + QEEK+Q QEEK+QEQEE  W      +QEEK+ EQEEKMW
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506

Query: 150 EQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEI 200
            QEEKM EQEEKM+EQEEKMQ QEEKMR+ E    +  E   +     QE+
Sbjct: 507 RQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL 557



 Score =  222 bits (566), Expect = 2e-58
 Identities = 112/177 (63%), Positives = 149/177 (84%), Gaps = 5/177 (2%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
           +EE+M E+E K+RE+EE M  QEEKM EQEEK+REQE+KMW QEEK++EQEEK+ EQEEK
Sbjct: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368

Query: 63  MWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR---EKKKTQEE 118
           MW QEEK+ EQ +++ EQ+E+MW Q+E++RE+EE+ R++KMW+Q +KMR   EK + QEE
Sbjct: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK-RQEKMWRQEKKMREQDEKIREQEE 427

Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175
           +M  QEEK++E EEMM +QEEK++E EEKM E+EEKM+EQEEK++ QEEK+Q QEEK
Sbjct: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484



 Score =  215 bits (548), Expect = 2e-56
 Identities = 108/183 (59%), Positives = 150/183 (81%), Gaps = 10/183 (5%)

Query: 8   REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67
           +++E+KM  +EE ++EQEEKM EQE K+REQEEKMW QEEKM EQEEK+ EQE+KMW QE
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352

Query: 68  EKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKT-------QE 117
           EK+ EQ+ ++ EQ+EKMW Q+E++RE++E+++EQ+  MW+Q EK+RE+++        QE
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412

Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
           +KM+EQ+EK++EQEE MW QEEK++E EE M +QEEK+RE EEKM+E+EEKMQ QEEK++
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472

Query: 178 DVE 180
             E
Sbjct: 473 RQE 475



 Score =  186 bits (471), Expect = 2e-47
 Identities = 107/182 (58%), Positives = 135/182 (74%), Gaps = 27/182 (14%)

Query: 16  EEEEMM----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 71
           EE E+     ++QEEKM  QEEK++EQEEKM EQE K++EQEEKMW QEEKM EQEEK  
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK-- 340

Query: 72  EQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEEKMQEQEEKMQE 129
               + EQ++KMW Q+E++RE+EE++REQ  KMW+Q EK+RE    Q+EK+QEQEE+M  
Sbjct: 341 ----IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE----QDEKIQEQEEEMWR 392

Query: 130 QEEMMWEQEEKMQE----QEEKMWEQEEKMRE-------QEEKMREQEEKMQGQEEKMRD 178
           QEE + EQEEK QE    QE+KM EQ+EK+RE       QEEK+RE EE MQ QEEK+R+
Sbjct: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLRE 452

Query: 179 VE 180
           VE
Sbjct: 453 VE 454



 Score =  162 bits (410), Expect = 2e-40
 Identities = 95/210 (45%), Positives = 131/210 (62%), Gaps = 40/210 (19%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+EE++RE E+ M+++EE +RE EEKMQE+EEKM+EQEEK+  QEEK+QEQEEK W QE 
Sbjct: 431 RQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE- 489

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121
           K+ +QEEK+WEQ+      EKMW Q+E++ E+EE+M+EQ+     EKM+           
Sbjct: 490 KLLKQEEKIWEQE------EKMWRQEEKMWEQEEKMQEQE-----EKMQ----------- 527

Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEP 181
            QEEKM+EQE  +W+QEEKMQEQE ++ E EE++ +  +K                  E 
Sbjct: 528 RQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK-----------------AEL 570

Query: 182 AGGEAGEGSPQDNPTAQEIMQLFCGMKNAQ 211
            GG   E   Q  PT   I+Q+    + AQ
Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQ 600



 Score =  132 bits (332), Expect = 3e-31
 Identities = 71/194 (36%), Positives = 131/194 (67%), Gaps = 22/194 (11%)

Query: 4   EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK--MWEQEEKMQEQEEKMWEQEE 61
           +E ++E+  +++E+  ++  ++ ++Q   + ++ + E+  +   ++++Q + +++ ++ +
Sbjct: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ 272

Query: 62  KMWEQEEKMWEQQRL-----PEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKK-- 114
            +  + +   E+  L      +Q+EKMW Q+E+++E+EE+M EQ+      K+RE+++  
Sbjct: 273 SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE-----LKIREQEEKM 327

Query: 115 -TQEEKMQEQEEKMQEQEEMMW-------EQEEKMQEQEEKMWEQEEKMREQEEKMREQE 166
             QEEKM EQEEK++EQE+ MW       EQEEK++EQEEKMW QEEK+REQ+EK++EQE
Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387

Query: 167 EKMQGQEEKMRDVE 180
           E+M  QEEK+R+ E
Sbjct: 388 EEMWRQEEKIREQE 401



 Score =  100 bits (250), Expect = 8e-22
 Identities = 59/134 (44%), Positives = 86/134 (64%), Gaps = 10/134 (7%)

Query: 2   REEERMRE------REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 55
           R+EE+++E      R++K+ ++EE + EQEEKM  QEEKM EQEEKM EQEEKMQ QEEK
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532

Query: 56  MWEQEEKMWEQEEKMWEQ----QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMRE 111
           M EQE ++W+QEEKM EQ    Q L E+  K+ ++ E L         Q++      ++ 
Sbjct: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQV 592

Query: 112 KKKTQEEKMQEQEE 125
           + K+QE +  +Q++
Sbjct: 593 ELKSQEAQSLQQQQ 606



 Score = 95.5 bits (236), Expect = 4e-20
 Identities = 61/182 (33%), Positives = 102/182 (56%), Gaps = 5/182 (2%)

Query: 4   EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE----KMWEQEEKMQEQEEKMWEQ 59
           E   ++R +    EE +  +   +M    EK+ ++ +    +++      +E +EK  E 
Sbjct: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAEL 223

Query: 60  EEKM-WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
           +EK+   + EK   Q  + + K K+      L +++ ++   ++ ++++ +  K + Q E
Sbjct: 224 QEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE 283

Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
           + +      Q+QEE MW QEEK+QEQEEKM EQE K+REQEEKM  QEEKM  QEEK+R+
Sbjct: 284 ENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE 343

Query: 179 VE 180
            E
Sbjct: 344 QE 345



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 61/267 (22%), Positives = 103/267 (38%), Gaps = 93/267 (34%)

Query: 5   ERMREREKKMREEEEMMREQEEKMQEQEEKMRE----------QEEKMWEQEEKMQEQEE 54
           E  + R  K  +E++ + E E+  Q +E   R           ++  +   ++   E + 
Sbjct: 74  ENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKS 133

Query: 55  KMWEQEEKMWEQE---------EKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQ 105
              +++EKM E+          +K W   RL E   +   ++  L E        +M   
Sbjct: 134 SFKKRQEKMNEKNYTFRKRVVIKKPW--LRLGEVTAQKRPENSLLEETLHFDHAVRMGTY 191

Query: 106 VEKMREKK--------------KTQEEKMQEQEEKMQ--------------------EQE 131
           +EK+ +++              +  +EK  E +EK++                    E+ 
Sbjct: 192 IEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251

Query: 132 EMMWEQEE-----------------KMQEQEE--------------KMWEQEEKMREQEE 160
           +++  Q++                 K+Q Q E              KMW QEEK++EQEE
Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311

Query: 161 KM-------REQEEKMQGQEEKMRDVE 180
           KM       REQEEKM  QEEKM + E
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQE 338



 Score = 28.1 bits (61), Expect = 7.0
 Identities = 21/102 (20%), Positives = 43/102 (42%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           ++EE+M+E+E +++E EE + +  +K +      RE   +       + + E K  E + 
Sbjct: 542 QQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW 103
              +Q+      Q+     +++    E L     R    K W
Sbjct: 602 LQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRW 643


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score =  226 bits (575), Expect = 2e-59
 Identities = 121/231 (52%), Positives = 162/231 (70%), Gaps = 34/231 (14%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+EE+M E+E+K+RE+E+ M  QEEK++EQEEK+REQEEKMW QEEK++EQ+EK+ EQEE
Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMR--------- 110
           +MW QEEK+ EQ+   +++EKMW Q++++RE++E++REQ  +MW+Q EK+R         
Sbjct: 389 EMWRQEEKIREQEE--KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ 446

Query: 111 ---------------EKKKTQEEKMQEQEEKMQEQEEMMW------EQEEKMQEQEEKMW 149
                          EK + QEEK+Q QEEK+QEQEE  W      +QEEK+ EQEEKMW
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506

Query: 150 EQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEI 200
            QEEKM EQEEKM+EQEEKMQ QEEKMR+ E    +  E   +     QE+
Sbjct: 507 RQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL 557



 Score =  222 bits (566), Expect = 2e-58
 Identities = 112/177 (63%), Positives = 149/177 (84%), Gaps = 5/177 (2%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
           +EE+M E+E K+RE+EE M  QEEKM EQEEK+REQE+KMW QEEK++EQEEK+ EQEEK
Sbjct: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEK 368

Query: 63  MWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR---EKKKTQEE 118
           MW QEEK+ EQ +++ EQ+E+MW Q+E++RE+EE+ R++KMW+Q +KMR   EK + QEE
Sbjct: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK-RQEKMWRQEKKMREQDEKIREQEE 427

Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175
           +M  QEEK++E EEMM +QEEK++E EEKM E+EEKM+EQEEK++ QEEK+Q QEEK
Sbjct: 428 EMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484



 Score =  215 bits (548), Expect = 2e-56
 Identities = 108/183 (59%), Positives = 150/183 (81%), Gaps = 10/183 (5%)

Query: 8   REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67
           +++E+KM  +EE ++EQEEKM EQE K+REQEEKMW QEEKM EQEEK+ EQE+KMW QE
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352

Query: 68  EKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKT-------QE 117
           EK+ EQ+ ++ EQ+EKMW Q+E++RE++E+++EQ+  MW+Q EK+RE+++        QE
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412

Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
           +KM+EQ+EK++EQEE MW QEEK++E EE M +QEEK+RE EEKM+E+EEKMQ QEEK++
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472

Query: 178 DVE 180
             E
Sbjct: 473 RQE 475



 Score =  186 bits (471), Expect = 2e-47
 Identities = 107/182 (58%), Positives = 135/182 (74%), Gaps = 27/182 (14%)

Query: 16  EEEEMM----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 71
           EE E+     ++QEEKM  QEEK++EQEEKM EQE K++EQEEKMW QEEKM EQEEK  
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEK-- 340

Query: 72  EQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEEKMQEQEEKMQE 129
               + EQ++KMW Q+E++RE+EE++REQ  KMW+Q EK+RE    Q+EK+QEQEE+M  
Sbjct: 341 ----IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE----QDEKIQEQEEEMWR 392

Query: 130 QEEMMWEQEEKMQE----QEEKMWEQEEKMRE-------QEEKMREQEEKMQGQEEKMRD 178
           QEE + EQEEK QE    QE+KM EQ+EK+RE       QEEK+RE EE MQ QEEK+R+
Sbjct: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLRE 452

Query: 179 VE 180
           VE
Sbjct: 453 VE 454



 Score =  162 bits (410), Expect = 2e-40
 Identities = 95/210 (45%), Positives = 131/210 (62%), Gaps = 40/210 (19%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+EE++RE E+ M+++EE +RE EEKMQE+EEKM+EQEEK+  QEEK+QEQEEK W QE 
Sbjct: 431 RQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE- 489

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121
           K+ +QEEK+WEQ+      EKMW Q+E++ E+EE+M+EQ+     EKM+           
Sbjct: 490 KLLKQEEKIWEQE------EKMWRQEEKMWEQEEKMQEQE-----EKMQ----------- 527

Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEP 181
            QEEKM+EQE  +W+QEEKMQEQE ++ E EE++ +  +K                  E 
Sbjct: 528 RQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK-----------------AEL 570

Query: 182 AGGEAGEGSPQDNPTAQEIMQLFCGMKNAQ 211
            GG   E   Q  PT   I+Q+    + AQ
Sbjct: 571 LGGAGRESGSQRLPTLTPILQVELKSQEAQ 600



 Score =  132 bits (332), Expect = 3e-31
 Identities = 71/194 (36%), Positives = 131/194 (67%), Gaps = 22/194 (11%)

Query: 4   EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK--MWEQEEKMQEQEEKMWEQEE 61
           +E ++E+  +++E+  ++  ++ ++Q   + ++ + E+  +   ++++Q + +++ ++ +
Sbjct: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ 272

Query: 62  KMWEQEEKMWEQQRL-----PEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKK-- 114
            +  + +   E+  L      +Q+EKMW Q+E+++E+EE+M EQ+      K+RE+++  
Sbjct: 273 SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE-----LKIREQEEKM 327

Query: 115 -TQEEKMQEQEEKMQEQEEMMW-------EQEEKMQEQEEKMWEQEEKMREQEEKMREQE 166
             QEEKM EQEEK++EQE+ MW       EQEEK++EQEEKMW QEEK+REQ+EK++EQE
Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387

Query: 167 EKMQGQEEKMRDVE 180
           E+M  QEEK+R+ E
Sbjct: 388 EEMWRQEEKIREQE 401



 Score =  100 bits (250), Expect = 8e-22
 Identities = 59/134 (44%), Positives = 86/134 (64%), Gaps = 10/134 (7%)

Query: 2   REEERMRE------REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 55
           R+EE+++E      R++K+ ++EE + EQEEKM  QEEKM EQEEKM EQEEKMQ QEEK
Sbjct: 473 RQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532

Query: 56  MWEQEEKMWEQEEKMWEQ----QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMRE 111
           M EQE ++W+QEEKM EQ    Q L E+  K+ ++ E L         Q++      ++ 
Sbjct: 533 MREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQV 592

Query: 112 KKKTQEEKMQEQEE 125
           + K+QE +  +Q++
Sbjct: 593 ELKSQEAQSLQQQQ 606



 Score = 95.5 bits (236), Expect = 4e-20
 Identities = 61/182 (33%), Positives = 102/182 (56%), Gaps = 5/182 (2%)

Query: 4   EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE----KMWEQEEKMQEQEEKMWEQ 59
           E   ++R +    EE +  +   +M    EK+ ++ +    +++      +E +EK  E 
Sbjct: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAEL 223

Query: 60  EEKM-WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
           +EK+   + EK   Q  + + K K+      L +++ ++   ++ ++++ +  K + Q E
Sbjct: 224 QEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVE 283

Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
           + +      Q+QEE MW QEEK+QEQEEKM EQE K+REQEEKM  QEEKM  QEEK+R+
Sbjct: 284 ENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE 343

Query: 179 VE 180
            E
Sbjct: 344 QE 345



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 61/267 (22%), Positives = 103/267 (38%), Gaps = 93/267 (34%)

Query: 5   ERMREREKKMREEEEMMREQEEKMQEQEEKMRE----------QEEKMWEQEEKMQEQEE 54
           E  + R  K  +E++ + E E+  Q +E   R           ++  +   ++   E + 
Sbjct: 74  ENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKS 133

Query: 55  KMWEQEEKMWEQE---------EKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQ 105
              +++EKM E+          +K W   RL E   +   ++  L E        +M   
Sbjct: 134 SFKKRQEKMNEKNYTFRKRVVIKKPW--LRLGEVTAQKRPENSLLEETLHFDHAVRMGTY 191

Query: 106 VEKMREKK--------------KTQEEKMQEQEEKMQ--------------------EQE 131
           +EK+ +++              +  +EK  E +EK++                    E+ 
Sbjct: 192 IEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251

Query: 132 EMMWEQEE-----------------KMQEQEE--------------KMWEQEEKMREQEE 160
           +++  Q++                 K+Q Q E              KMW QEEK++EQEE
Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311

Query: 161 KM-------REQEEKMQGQEEKMRDVE 180
           KM       REQEEKM  QEEKM + E
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQE 338



 Score = 28.1 bits (61), Expect = 7.0
 Identities = 21/102 (20%), Positives = 43/102 (42%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           ++EE+M+E+E +++E EE + +  +K +      RE   +       + + E K  E + 
Sbjct: 542 QQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS 601

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW 103
              +Q+      Q+     +++    E L     R    K W
Sbjct: 602 LQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRW 643


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score =  222 bits (566), Expect = 2e-58
 Identities = 115/182 (63%), Positives = 153/182 (84%), Gaps = 6/182 (3%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
           +E++M  +E+K+RE+EE +  QEEK++EQEEK +EQEEKMW+QEEK++EQEEK+ EQEEK
Sbjct: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627

Query: 63  MWEQEEKMWEQQRLP-EQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKT---Q 116
           + EQEEK+ EQ+ +  EQ+EKM EQ+E++ E+EE+M+EQ+  MW+Q EK+RE++K    Q
Sbjct: 628 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQ 687

Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
           EEK++EQEE MQEQEE MWEQEEKM EQEEKM EQEEKMR QEEKM EQE +++ QEEKM
Sbjct: 688 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 747

Query: 177 RD 178
           ++
Sbjct: 748 QE 749



 Score =  220 bits (561), Expect = 7e-58
 Identities = 118/231 (51%), Positives = 160/231 (69%), Gaps = 35/231 (15%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R++E+M E+E+K+R++EE +  QEEK++EQEEK+REQEEKMW QEEK++EQEE MW +EE
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE-MWREEE 551

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERM----------------REQKMWQQ 105
           KM EQE K+WE+++  EQ++KMW Q+E++RE+EE++                +E+KMW+Q
Sbjct: 552 KMHEQE-KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610

Query: 106 VEKMREKK-----------------KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKM 148
            EK+RE++                 + QEE  QEQEEKM EQEE M EQEEKMQEQEE M
Sbjct: 611 EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM 670

Query: 149 WEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199
           W QEEK+REQE+K+REQEEK++ QEE M++ E    E  E   +     QE
Sbjct: 671 WRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 721



 Score =  219 bits (559), Expect = 1e-57
 Identities = 119/192 (61%), Positives = 153/192 (79%), Gaps = 15/192 (7%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           REEE+M E+EK    EEE  +EQE+KM  QEEK+REQEEK+W QEEK++EQEEK  EQEE
Sbjct: 548 REEEKMHEQEKIW--EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605

Query: 62  KMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ---------KMWQQVEKMRE 111
           KMW+QEEK+ EQ+ ++ EQ+EK+ EQ+E++RE+EE  +EQ         KM +Q EKM+E
Sbjct: 606 KMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 665

Query: 112 KKKT---QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168
           +++T   QEEK++EQE+K++EQEE + EQEE MQEQEEKMWEQEEKM EQEEKM+EQEEK
Sbjct: 666 QEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725

Query: 169 MQGQEEKMRDVE 180
           M+ QEEKM + E
Sbjct: 726 MRRQEEKMWEQE 737



 Score =  217 bits (552), Expect = 8e-57
 Identities = 112/198 (56%), Positives = 152/198 (76%), Gaps = 4/198 (2%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           +E+E M  +E+K+ E+EE+ R Q+EKM EQEEK+R+QEEK+W QEEK++EQEEK+ EQEE
Sbjct: 473 QEQEEMWRQEEKIHEQEEIWR-QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEE 531

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT---QEE 118
           KMW QEEK+ EQ+ +  ++EKM EQ++   E++ + +E KMW+Q EK+RE+++    QEE
Sbjct: 532 KMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE 591

Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
           K++EQEEK QEQEE MW+QEEK++EQEEK+ EQEEK+REQEEK+REQEE  Q QEEKM +
Sbjct: 592 KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE 651

Query: 179 VEPAGGEAGEGSPQDNPT 196
            E    E  E   +   T
Sbjct: 652 QEEKMCEQEEKMQEQEET 669



 Score =  215 bits (548), Expect = 2e-56
 Identities = 115/206 (55%), Positives = 156/206 (75%), Gaps = 28/206 (13%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE-------- 53
           +EEE++RE+EK+  +E +M R QEEK++EQEEK+REQE+KMW QEEK+ EQE        
Sbjct: 414 QEEEKIREQEKRQEQEAKMWR-QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 472

Query: 54  ---EKMWEQEEKM------WEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ--K 101
              E+MW QEEK+      W Q+EKM EQ+ ++ +Q+EK+W Q+E++RE+EE++REQ  K
Sbjct: 473 QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEK 532

Query: 102 MWQQVEKMREKKKT--QEEKMQEQE-----EKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 154
           MW+Q EK+RE+++   +EEKM EQE     EK QEQE+ MW QEEK++EQEEK+W QEEK
Sbjct: 533 MWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK 592

Query: 155 MREQEEKMREQEEKMQGQEEKMRDVE 180
           +REQEEK +EQEEKM  QEEK+R+ E
Sbjct: 593 IREQEEKRQEQEEKMWKQEEKIREQE 618



 Score =  213 bits (543), Expect = 9e-56
 Identities = 121/241 (50%), Positives = 163/241 (67%), Gaps = 41/241 (17%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQ-------EQEEKMREQEEKMWEQEEKMQEQEEK 55
           +EE++RE+E+KMR +EEMM E+EEKM+       E+EEKMR QEE MWE+EEKM+ QEE 
Sbjct: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 385

Query: 56  MWEQEEKMWEQEEKMWEQQRLPEQKE-------------------KMWEQDERLREKEER 96
           MWE+EEK+ E EEKM EQ+++ EQ+E                   KMW Q+E++RE+EE+
Sbjct: 386 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 445

Query: 97  MREQ--KMWQQVEKMREKKKTQE-------EKMQEQEEKMQEQEEM------MWEQEEKM 141
           +REQ  KMW+Q EK+ E++K +E       E+M  QEEK+ EQEE+      M EQEEK+
Sbjct: 446 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505

Query: 142 QEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEIM 201
           ++QEEK+W QEEK+REQEEK+REQEEKM  QEEK+R+ E    E  +   Q+    +E  
Sbjct: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKR 565

Query: 202 Q 202
           Q
Sbjct: 566 Q 566



 Score =  207 bits (528), Expect = 5e-54
 Identities = 110/220 (50%), Positives = 153/220 (69%), Gaps = 41/220 (18%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+EE+++E E+K++E+EE +REQEEK++EQEEKMR QEE MWE+EEKM+ QEE MWE+EE
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363

Query: 62  KMWEQEEKMWE-QQRLPEQKEKMWEQDERLREKEERMREQKMW-------QQVEKMREKK 113
           KM  QEE MWE ++++  Q+E MWE++E++RE EE+M EQ+         Q+ EK+RE++
Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423

Query: 114 KTQE---------EKMQEQEEKMQEQEEMMWEQEEKMQEQE------------------- 145
           K QE         EK++EQEEK++EQE+ MW QEEK+ EQE                   
Sbjct: 424 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 483

Query: 146 -----EKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
                E++W Q+EKM EQEEK+R+QEEK+  QEEK+R+ E
Sbjct: 484 KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQE 523



 Score =  198 bits (503), Expect = 4e-51
 Identities = 112/212 (52%), Positives = 152/212 (71%), Gaps = 16/212 (7%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE-----EKM 56
           R+EE M E+E+KMR +EEMM E+EEK++E EEKM EQE K+ EQEEK QE+E     EK 
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KIREQEEKRQEEEKIREQEKR 425

Query: 57  WEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQD------ERLREKEERMREQKMWQQVEKM 109
            EQE KMW QEEK+ EQ+ ++ EQ++KMW Q+      E++RE+E+R  +++MW+Q EK+
Sbjct: 426 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 485

Query: 110 REKKK--TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167
            E+++   Q+EKM EQEEK+++QEE +W QEEK++EQEEK+ EQEEKM  QEEK+REQEE
Sbjct: 486 HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE 545

Query: 168 KMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199
            M  +EEKM + E    E      +D    QE
Sbjct: 546 -MWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576



 Score =  187 bits (476), Expect = 5e-48
 Identities = 100/169 (59%), Positives = 137/169 (81%), Gaps = 13/169 (7%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+EE++RE+E+K +E+EE M +QEEK++EQEEK++EQEEK+ EQEEK++EQEE   EQEE
Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE 647

Query: 62  KMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKT--- 115
           KM EQEEKM EQ+ ++ EQ+E MW Q+E++RE+E+++REQ  K+ +Q E M+E+++    
Sbjct: 648 KMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707

Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164
           QEEKM EQEEKMQ       EQEEKM+ QEEKMWEQE ++R+QEEKM+E
Sbjct: 708 QEEKMCEQEEKMQ-------EQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749



 Score =  158 bits (399), Expect = 4e-39
 Identities = 90/187 (48%), Positives = 130/187 (69%), Gaps = 20/187 (10%)

Query: 1   MREEERMREREKKMREEEEMMREQE---EKMQEQEEKMREQ--EEKMWEQEEKMQEQEEK 55
           ++E +R  ER K +  ++++  E +   +++Q    K++ Q  E ++W +    Q+QEEK
Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN--QQQEEK 301

Query: 56  MWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMR--EQKMWQQVEKMREKK 113
           MW QEEK+ E EEK      + EQ+EK+ EQ+E++RE+EE+MR  E+ MW++ EKMR   
Sbjct: 302 MWRQEEKIQEWEEK------IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR-- 353

Query: 114 KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 173
             QEE M E+EEKM+ QEEMMWE+EEKM+ QEE MWE+EEK+RE EEKM EQ EK++ QE
Sbjct: 354 --QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ-EKIREQE 410

Query: 174 EKMRDVE 180
           EK ++ E
Sbjct: 411 EKRQEEE 417



 Score =  135 bits (340), Expect = 3e-32
 Identities = 75/125 (60%), Positives = 98/125 (78%), Gaps = 13/125 (10%)

Query: 1   MREEERM-REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
           +RE+E M +E+E+KM E+EE M EQEEKMQEQEE M  QEEK+ EQE+K++EQEEK+ EQ
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694

Query: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMR--EQKMWQQVEKMREKKKTQE 117
           EE M EQEEKMWEQ+      EKM EQ+E+++E+EE+MR  E+KMW+Q  ++R+    QE
Sbjct: 695 EEMMQEQEEKMWEQE------EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ----QE 744

Query: 118 EKMQE 122
           EKMQE
Sbjct: 745 EKMQE 749



 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 65/195 (33%), Positives = 90/195 (46%), Gaps = 74/195 (37%)

Query: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK-------------------------- 93
           EE   E++    E  R     E++ E++ +L+EK                          
Sbjct: 196 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 255

Query: 94  --------------------------EERMREQKMW-----QQVEKM-REKKKTQE---- 117
                                     + ++ E ++W     QQ EKM R+++K QE    
Sbjct: 256 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK 315

Query: 118 ------------EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 165
                       EK++EQEEKM+ QEEMMWE+EEKM+ QEE MWE+EEKMR QEE M E+
Sbjct: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 375

Query: 166 EEKMQGQEEKMRDVE 180
           EEKM+ QEE M + E
Sbjct: 376 EEKMRRQEEMMWEKE 390


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score =  218 bits (554), Expect = 5e-57
 Identities = 115/185 (62%), Positives = 153/185 (82%), Gaps = 7/185 (3%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           +E+E M  +E+K+RE+EE+ R Q+EK+ EQEEK+R+QEEKMW QEEKM +QEEK+ EQEE
Sbjct: 520 QEQEEMWRQEEKIREQEEIWR-QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEE 578

Query: 62  KMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERM--REQKMWQQVEKMR---EKKKT 115
           K+W QEEK+ EQ +++ EQ+EK+ EQ+E  +E+EE+M  +E+KM +Q EKM+   EK + 
Sbjct: 579 KVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRR 638

Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175
           QEEK++EQE+K++EQEE + EQEE MQEQEEKMWEQEEKM EQEEKM+EQEEKM+ QEEK
Sbjct: 639 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 698

Query: 176 MRDVE 180
           M + E
Sbjct: 699 MWEQE 703



 Score =  216 bits (549), Expect = 2e-56
 Identities = 118/231 (51%), Positives = 159/231 (68%), Gaps = 34/231 (14%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
           +EE++RE+E+K+RE+EE MR QEE M E+EEKMR QEE MWE+EEKM+ QEE MWE+EEK
Sbjct: 380 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 439

Query: 63  MWEQEEKMWEQQRLPEQKEK-------------------MWEQDERLREKEERMREQ--K 101
           + E EEKM EQ+++ EQ+EK                   MW Q+E++RE+EE++REQ  K
Sbjct: 440 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499

Query: 102 MWQQVEKMREKKKTQEEK-------MQEQEEKMQEQEEM------MWEQEEKMQEQEEKM 148
           MW+Q EK+ E++K +EE+       M  QEEK++EQEE+      + EQEEK+++QEEKM
Sbjct: 500 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKM 559

Query: 149 WEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199
           W QEEKM +QEEK+REQEEK+  QEEK+R+ E    E  E   +     QE
Sbjct: 560 WRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQE 610



 Score =  216 bits (549), Expect = 2e-56
 Identities = 108/178 (60%), Positives = 148/178 (83%), Gaps = 3/178 (1%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R++E++ E+E+K+R++EE M  QEEKM +QEEK+REQEEK+W QEEK++EQEEK+ EQEE
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599

Query: 62  KMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
           K+ EQEE   EQ +++ EQ+EKM EQ+E+++E+EE+MR Q+  +++ +  +K + QEEK+
Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQE--EKIREQEKKIREQEEKI 657

Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
           +EQEE MQEQEE MWEQEEKM EQEEKM EQEEKMR QEEKM EQE +++ QEEKM++
Sbjct: 658 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715



 Score =  214 bits (545), Expect = 5e-56
 Identities = 119/231 (51%), Positives = 162/231 (70%), Gaps = 25/231 (10%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE-------- 53
           +EEE++RE+EK+  +E +M R QEEK++EQEEK+REQEEKMW QEEK+ EQE        
Sbjct: 461 QEEEKIREQEKRQEQEAKMWR-QEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKR 519

Query: 54  ---EKMWEQEEK------MWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQ--K 101
              E+MW QEEK      +W Q+EK+ EQ +++ +Q+EKMW Q+E++ ++EE++REQ  K
Sbjct: 520 QEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEK 579

Query: 102 MWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK 161
           +W+Q EK+RE    QEEK++EQEEK++EQEEM  EQEEKM EQEEKM EQEEKM+EQEEK
Sbjct: 580 VWRQEEKIRE----QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEK 635

Query: 162 MREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQ 212
           MR QEEK++ QE+K+R+ E    E  E   +      E  +  C  +   Q
Sbjct: 636 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 686



 Score =  208 bits (529), Expect = 4e-54
 Identities = 115/207 (55%), Positives = 150/207 (72%), Gaps = 29/207 (14%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+EE+++E E+K++E+EE +REQEEK++EQEEKMR QEE MWE+EEKM+ QEE MWE+EE
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424

Query: 62  KMWEQEEKMWE-QQRLPEQKEKMWEQD-----ERLREKEERMREQ--------KMWQQVE 107
           KM  QEE MWE ++++ E +EKM EQ+     E  R++EE++REQ        KMW+Q E
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484

Query: 108 KMR---EKKKTQEEKMQEQEEKMQEQE-----------EMMWEQEEKMQEQEEKMWEQEE 153
           K+R   EK + QEEKM  QEEK+ EQE           E MW QEEK++EQEE +W Q+E
Sbjct: 485 KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE-IWRQKE 543

Query: 154 KMREQEEKMREQEEKMQGQEEKMRDVE 180
           K+ EQEEK+R+QEEKM  QEEKM D E
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQE 570



 Score =  197 bits (501), Expect = 7e-51
 Identities = 103/180 (57%), Positives = 142/180 (78%), Gaps = 7/180 (3%)

Query: 8   REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67
           +++E+KM  +EE ++E EEK+QEQEEK+REQEEK+ EQEEKM+ QEE MWE+EEKM  QE
Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 416

Query: 68  EKMWE-QQRLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMREKKKTQE-EKMQEQE 124
           E MWE ++++  Q+E MWE++E++RE EE+M EQ K+ +Q EK +E++K +E EK QEQE
Sbjct: 417 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 476

Query: 125 EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ----EEKMREQEEKMQGQEEKMRDVE 180
            KM  QEE + EQEEK++EQEEKMW QEEK+ EQ    EE+ R+++E+M  QEEK+R+ E
Sbjct: 477 AKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 536



 Score =  190 bits (483), Expect = 8e-49
 Identities = 99/170 (58%), Positives = 136/170 (80%), Gaps = 10/170 (5%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+EE+M ++E+K+RE+EE +  QEEK++EQEEK+REQEEK+ EQEE  QEQEEKM EQEE
Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620

Query: 62  KMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
           KM EQEEKM EQ+ ++  Q+EK+ EQ++++RE+EE++REQ+  + +++  EK   QEEKM
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE--EMMQEQEEKMWEQEEKM 678

Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 170
            EQEEKMQ       EQEEKM+ QEEKMWEQE ++R+QEEKM+E +E ++
Sbjct: 679 CEQEEKMQ-------EQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721



 Score =  147 bits (371), Expect = 8e-36
 Identities = 95/200 (47%), Positives = 134/200 (67%), Gaps = 27/200 (13%)

Query: 1   MREEERMREREKKMREEEEMMREQEE----------KMQEQEEKM-------REQEEKMW 43
           ++E +R  ER K +  ++++  E +           K+Q Q E+        ++QEEKMW
Sbjct: 305 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 364

Query: 44  EQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERM--REQ 100
            QEEK+QE EEK+ EQEEK+ EQEEK+ EQ+ ++  Q+E MWE++E++R +EE M  +E+
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424

Query: 101 KMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160
           KM +Q E M EK    EEK++E EEKM EQE++  EQEEK QE EEK+ EQE K +EQE 
Sbjct: 425 KMRRQEEMMWEK----EEKIRELEEKMHEQEKIR-EQEEKRQE-EEKIREQE-KRQEQEA 477

Query: 161 KMREQEEKMQGQEEKMRDVE 180
           KM  QEEK++ QEEK+R+ E
Sbjct: 478 KMWRQEEKIREQEEKIREQE 497



 Score =  144 bits (364), Expect = 5e-35
 Identities = 78/131 (59%), Positives = 104/131 (79%), Gaps = 13/131 (9%)

Query: 1   MREEERM-REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
           +RE+E M +E+E+KM E+EE M EQEEKMQEQEEKMR QEEK+ EQE+K++EQEEK+ EQ
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 660

Query: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMR--EQKMWQQVEKMREKKKTQE 117
           EE M EQEEKMWEQ+      EKM EQ+E+++E+EE+MR  E+KMW+Q  ++R+    QE
Sbjct: 661 EEMMQEQEEKMWEQE------EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ----QE 710

Query: 118 EKMQEQEEKMQ 128
           EKMQE +E ++
Sbjct: 711 EKMQEHQEHLE 721



 Score = 85.5 bits (210), Expect = 4e-17
 Identities = 64/181 (35%), Positives = 89/181 (49%), Gaps = 60/181 (33%)

Query: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK-------------------------- 93
           EE   E++    E  R     E++ E++ +L+EK                          
Sbjct: 257 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 316

Query: 94  --------------------------EERMREQKMW-----QQVEKM-REKKKTQ--EEK 119
                                     + ++ E ++W     QQ EKM R+++K Q  EEK
Sbjct: 317 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK 376

Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDV 179
           +QEQEEK++EQEE + EQEEKM+ QEE MWE+EEKMR QEE M E+EEKM+ QEE M + 
Sbjct: 377 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 436

Query: 180 E 180
           E
Sbjct: 437 E 437


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score =  216 bits (549), Expect = 2e-56
 Identities = 112/177 (63%), Positives = 145/177 (81%), Gaps = 6/177 (3%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           ++EE++  +E+KM ++EE +REQEEKM  QEEK+REQEEK+ EQEEK++EQEE M EQEE
Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEE 551

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEEK 119
           KM EQEEKM EQ+++  Q+EK+ EQ+E++RE++E++REQ  K+W+Q EK+RE    QEE 
Sbjct: 552 KMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE----QEEM 607

Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
           MQEQEEKM EQEE M EQEEKMQEQEEKM  QEEKM EQE ++R+QEEKMQ  +E +
Sbjct: 608 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664



 Score =  214 bits (545), Expect = 5e-56
 Identities = 109/178 (61%), Positives = 145/178 (81%), Gaps = 2/178 (1%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
           M E+E++R++E+K+  +EE M +QEEK++EQEEKM  QEEK+ EQEEK++EQEEK+ EQE
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543

Query: 61  EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
           E M EQEEKM EQ+   +++EKM  Q+E++RE+EE++REQK  +++ +  EK   QEEK+
Sbjct: 544 EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK--EKIREQEEKIWEQEEKI 601

Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
           +EQEE MQEQEE MWEQEEKM EQEEKM EQEEKMR QEEKM EQE +++ QEEKM++
Sbjct: 602 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659



 Score =  213 bits (543), Expect = 9e-56
 Identities = 115/207 (55%), Positives = 157/207 (75%), Gaps = 29/207 (14%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE-------- 53
           +EEE++RE+EK+  +E +M R QEEK++EQEEK+REQE+KMW QEEK+ EQE        
Sbjct: 400 QEEEKIREQEKRQEQEAKMWR-QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 458

Query: 54  ---EKMWEQEEKM------WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KM 102
              E+MW QEEK+      W Q+EKM EQ+++ +Q+EK+W Q+E++ ++EE++REQ  KM
Sbjct: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518

Query: 103 WQQVEKMREKK---KTQEEKMQEQEEKMQEQEEMMWEQEEKMQE------QEEKMWEQEE 153
           W+Q EK+RE++   + QEEK++EQEE MQEQEE M EQEEKMQE      QEEK+ EQEE
Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE 578

Query: 154 KMREQEEKMREQEEKMQGQEEKMRDVE 180
           K+REQ+EK+REQEEK+  QEEK+R+ E
Sbjct: 579 KIREQKEKIREQEEKIWEQEEKIREQE 605



 Score =  212 bits (540), Expect = 2e-55
 Identities = 117/191 (61%), Positives = 153/191 (80%), Gaps = 14/191 (7%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           +E+E M  +E+K+RE+EE+ R Q+EKM EQE K+R+QEEK+W QEEKM +QEEK+ EQEE
Sbjct: 459 QEQEEMWRQEEKIREQEEIWR-QKEKMHEQE-KIRKQEEKVWRQEEKMHDQEEKIREQEE 516

Query: 62  KMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK-MWQQVEKMR---EKKKTQ 116
           KMW QEEK+ EQ+ ++ EQ+EK+ EQ+E ++E+EE+M EQ+   Q+ EKMR   EK + Q
Sbjct: 517 KMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576

Query: 117 EEKMQEQEEKMQEQEEMMWEQEEK-------MQEQEEKMWEQEEKMREQEEKMREQEEKM 169
           EEK++EQ+EK++EQEE +WEQEEK       MQEQEEKMWEQEEKM EQEEKM+EQEEKM
Sbjct: 577 EEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 636

Query: 170 QGQEEKMRDVE 180
           + QEEKM + E
Sbjct: 637 RRQEEKMWEQE 647



 Score =  212 bits (539), Expect = 3e-55
 Identities = 118/231 (51%), Positives = 156/231 (67%), Gaps = 35/231 (15%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
           +EE++RE+E+K+RE+EE MR QEE M E+EEKMR QEE MWE+EEKM+  EE MWE+EEK
Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378

Query: 63  MWEQEEKMWEQQRLPEQKEK-------------------MWEQDERLREKEERMREQ--K 101
           + E EEKM EQ+++ EQ+EK                   MW Q+E++RE+EE++REQ  K
Sbjct: 379 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 438

Query: 102 MWQQVEKMREKKKTQEEK-------MQEQEEKMQEQEEMMWEQEEKMQE------QEEKM 148
           MW+Q EK+ E++K +EE+       M  QEEK++EQEE+ W Q+EKM E      QEEK+
Sbjct: 439 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI-WRQKEKMHEQEKIRKQEEKV 497

Query: 149 WEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199
           W QEEKM +QEEK+REQEEKM  QEEK+R+ E    E  E   +     QE
Sbjct: 498 WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQE 548



 Score =  211 bits (537), Expect = 4e-55
 Identities = 119/230 (51%), Positives = 161/230 (70%), Gaps = 36/230 (15%)

Query: 1   MREEERMREREKKMREEEEM------------MREQEEKMQEQEEKMREQEEKMWEQEEK 48
           M E+E++RE+E+K +EEE++            M  QEEK++EQEEK+REQE+KMW QEEK
Sbjct: 386 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 445

Query: 49  MQEQE-----------EKMWEQEEK------MWEQEEKMWEQQRLPEQKEKMWEQDERLR 91
           + EQE           E+MW QEEK      +W Q+EKM EQ+++ +Q+EK+W Q+E++ 
Sbjct: 446 IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMH 505

Query: 92  EKEERMREQ--KMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMW 149
           ++EE++REQ  KMW+Q EK+RE    QEEK++EQEEK++EQEEMM EQEEKM EQEEKM 
Sbjct: 506 DQEEKIREQEEKMWRQEEKIRE----QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQ 561

Query: 150 EQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199
           EQ EKMR QEEK+REQEEK++ Q+EK+R+ E    E  E   +     QE
Sbjct: 562 EQ-EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQE 610



 Score =  209 bits (532), Expect = 2e-54
 Identities = 110/191 (57%), Positives = 149/191 (78%), Gaps = 14/191 (7%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQE-----EKMREQEEKMWEQEEKMQEQEEKMW 57
           +EE++RE E+KM E+E++ REQEEK QE+E     EK +EQE KMW QEEK++EQEEK+ 
Sbjct: 375 KEEKIRELEEKMHEQEKI-REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433

Query: 58  EQEEKMWEQEEKMWEQQRLPE-----QKEKMWEQDERLREKEERMREQKMWQQVEKMR-- 110
           EQE+KMW QEEK+ EQ+++ E     ++E+MW Q+E++RE+EE  R+++   + EK+R  
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493

Query: 111 -EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 169
            EK   QEEKM +QEEK++EQEE MW QEEK++EQEEK+ EQEEK+REQEE M+EQEEKM
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553

Query: 170 QGQEEKMRDVE 180
             QEEKM++ E
Sbjct: 554 GEQEEKMQEQE 564



 Score =  200 bits (509), Expect = 8e-52
 Identities = 121/262 (46%), Positives = 164/262 (62%), Gaps = 75/262 (28%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK-------MWEQEEKMQEQEE 54
           ++EE+M  +E+K++E EE ++EQEEK++EQEEK+REQEEK       MWE+EEKM+ QEE
Sbjct: 297 QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 356

Query: 55  KMWEQEEK-------MWEQ-------EEKMWEQQRLPEQKE------------------- 81
            MWE+EEK       MWE+       EEKM EQ+++ EQ+E                   
Sbjct: 357 MMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 416

Query: 82  KMWEQDERLREKEERMREQ--KMWQQVEKMREKKK--------------TQEEKMQEQE- 124
           KMW Q+E++RE+EE++REQ  KMW+Q EK+ E++K               QEEK++EQE 
Sbjct: 417 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 476

Query: 125 -----------EKMQEQEEMMWEQEEKM-------QEQEEKMWEQEEKMREQEEKMREQE 166
                      EK+++QEE +W QEEKM       +EQEEKMW QEEK+REQEEK+REQE
Sbjct: 477 IWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE 536

Query: 167 EKMQGQEEKMRDVEPAGGEAGE 188
           EK++ QEE M++ E   GE  E
Sbjct: 537 EKIREQEEMMQEQEEKMGEQEE 558



 Score =  193 bits (491), Expect = 1e-49
 Identities = 104/199 (52%), Positives = 147/199 (73%), Gaps = 7/199 (3%)

Query: 8   REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67
           +++E+KM  +EE ++E EEK+QEQEEK+REQEEK+ EQEEKM+ QEE MWE+EEKM  QE
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355

Query: 68  EKMWE-QQRLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMREKKKTQE-EKMQEQE 124
           E MWE ++++   +E MWE++E++RE EE+M EQ K+ +Q EK +E++K +E EK QEQE
Sbjct: 356 EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 415

Query: 125 EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ----EEKMREQEEKMQGQEEKMRDVE 180
            KM  QEE + EQEEK++EQE+KMW QEEK+ EQ    EE+ R+++E+M  QEEK+R+ E
Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 475

Query: 181 PAGGEAGEGSPQDNPTAQE 199
               +  +   Q+    QE
Sbjct: 476 EIWRQKEKMHEQEKIRKQE 494



 Score =  145 bits (365), Expect = 4e-35
 Identities = 92/201 (45%), Positives = 133/201 (66%), Gaps = 29/201 (14%)

Query: 1   MREEERMREREKKMREEEEMMREQEE----------KMQEQEEKM-------REQEEKMW 43
           ++E +R  ER K +  ++++  E +           K+Q Q E+        ++QEEKMW
Sbjct: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 303

Query: 44  EQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKM 102
            QEEK+QE EEK+ EQEEK+ EQEEK+ EQ+ ++  Q+E MWE++E++R +EE M     
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM----- 358

Query: 103 WQQVEKMREKKKT---QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 159
           W++ EKMR  ++    +EEK++E EEKM EQE++  EQEEK QE EEK+ EQE K +EQE
Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIR-EQEEKRQE-EEKIREQE-KRQEQE 415

Query: 160 EKMREQEEKMQGQEEKMRDVE 180
            KM  QEEK++ QEEK+R+ E
Sbjct: 416 AKMWRQEEKIREQEEKIREQE 436



 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 42/64 (65%), Positives = 54/64 (84%), Gaps = 1/64 (1%)

Query: 1   MREEER-MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
           +RE+E  M+E+E+KM E+EE M EQEEKMQEQEEKMR QEEKMWEQE ++++QEEKM E 
Sbjct: 601 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 660

Query: 60  EEKM 63
           +E +
Sbjct: 661 QEHL 664



 Score = 83.6 bits (205), Expect = 1e-16
 Identities = 59/174 (33%), Positives = 85/174 (48%), Gaps = 53/174 (30%)

Query: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK-------------------------- 93
           EE   E++    E  R     E++ E++ +L+EK                          
Sbjct: 196 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 255

Query: 94  --------------------------EERMREQKMWQQVEKMREKKK-TQEEKMQEQEEK 126
                                     + ++ E ++W ++ + +E+K   QEEK+QE EEK
Sbjct: 256 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK 315

Query: 127 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
           +QEQEE + EQEEK++EQEEKM  QEE M E+EEKMR QEE M  +EEKMR +E
Sbjct: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLE 369



 Score = 51.2 bits (121), Expect = 8e-07
 Identities = 27/49 (55%), Positives = 39/49 (79%), Gaps = 2/49 (4%)

Query: 3   EEERMREREKKMREEEEMM-REQEEKMQEQEEKMREQEEKMWEQEEKMQ 50
           +EE+M E+E+KM+E+EE   R QEEKM EQE ++R+QEEKM E +E ++
Sbjct: 618 QEEKMCEQEEKMQEQEEK-MRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score =  202 bits (513), Expect = 3e-52
 Identities = 107/204 (52%), Positives = 163/204 (79%), Gaps = 7/204 (3%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
           +EE+M+++E++M E+EE MR+QEE+M EQEE++++QEE++ +QEE+M++QEE+M EQEE+
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQ 270

Query: 63  MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKK---TQE 117
           M EQEE+M +Q+   EQ+E+  EQ+E++RE+EE+MREQ  +M +Q E+MRE+++    QE
Sbjct: 271 MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQE 330

Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
           E+M EQ+E+M EQ+E MW+QEE+M EQEE+M +QEE++R+QEE+MR+QEE+M+ QEE+MR
Sbjct: 331 EQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMR 390

Query: 178 DVEPAGGEAGE--GSPQDNPTAQE 199
             E   GE  E  G  ++    QE
Sbjct: 391 KQEEQMGEQKEQMGEQKEQMREQE 414



 Score =  197 bits (502), Expect = 5e-51
 Identities = 103/187 (55%), Positives = 151/187 (80%), Gaps = 16/187 (8%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQ-------------EQEEKMREQEEKMWEQEEK 48
           ++EE+MR++E++MRE+EE MREQEE+M              EQEE+MREQEE+M EQEE+
Sbjct: 252 KQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQ 311

Query: 49  MQEQEEKMWEQEEKMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVE 107
           M+EQEE+M EQEE+M +QEE+MWEQ +++ EQKE+MW+Q+E++ E+EE+M++Q+  +QV 
Sbjct: 312 MREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQE--EQVR 369

Query: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167
           K  E+ + QEE+M++QEE+M++QEE M EQ+E+M EQ+E+M EQEE+M EQ+E+MR+QEE
Sbjct: 370 KQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429

Query: 168 KMQGQEE 174
            M  Q+E
Sbjct: 430 HMGEQKE 436



 Score =  194 bits (493), Expect = 6e-50
 Identities = 105/198 (53%), Positives = 161/198 (81%), Gaps = 12/198 (6%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW----- 57
           +EE+MR++E++M E+EE +++QEE++Q+QEE+MR+QEE+M EQEE+M+EQEE+M      
Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQ 284

Query: 58  -EQEEKMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERM--REQKMWQQVEKMREKK 113
            EQEE+  EQEE+M EQ +++ EQ+E+M EQ+E++RE+EE+M  +E++MW+Q E+M E+K
Sbjct: 285 TEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQK 344

Query: 114 K---TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 170
           +    QEE+M EQEE+MQ+QEE + +QEE+M++QEE+M +QEE+MR+QEE+M EQ+E+M 
Sbjct: 345 EQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMG 404

Query: 171 GQEEKMRDVEPAGGEAGE 188
            Q+E+MR+ E   GE  E
Sbjct: 405 EQKEQMREQEEQMGEQKE 422



 Score =  186 bits (472), Expect = 2e-47
 Identities = 104/214 (48%), Positives = 157/214 (73%), Gaps = 34/214 (15%)

Query: 1   MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
           +RE+E ++RE+E ++RE+E  +REQE +M EQE +M EQEE+M EQEE+MQ+QEE+M EQ
Sbjct: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225

Query: 60  EEKMWEQEEKMWEQ--------QRLPEQKEKMWEQDERLREKEERMREQ----------- 100
           EE+M +QEE+M EQ        +++ +Q+E+M +Q+E++RE+EE+MREQ           
Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285

Query: 101 -----------KMWQQVEKMREKK---KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEE 146
                      +M +Q E+MRE++   + QEE+M+EQEE+M +QEE MWEQ+E+M EQ+E
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE 345

Query: 147 KMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
           +MW+QEE+M EQEE+M++QEE+++ QEE+MR  E
Sbjct: 346 QMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQE 379



 Score =  186 bits (472), Expect = 2e-47
 Identities = 102/198 (51%), Positives = 158/198 (79%), Gaps = 12/198 (6%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMW------EQEEKMQEQEEKM 56
           +EE+++++E++++++EE MR+QEE+M+EQEE+MREQEE+M       EQEE+  EQEE+M
Sbjct: 239 QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM 298

Query: 57  WEQEEKMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQK--MWQQVEKM---R 110
            EQEE+M EQEE+M EQ +++ EQ+E+M +Q+E++ E++E+M EQK  MW+Q E+M    
Sbjct: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQE 358

Query: 111 EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 170
           E+ + QEE++++QEE+M++QEE M +QEE+M++QEE+M EQ+E+M EQ+E+MREQEE+M 
Sbjct: 359 EQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMG 418

Query: 171 GQEEKMRDVEPAGGEAGE 188
            Q+E+MR  E   GE  E
Sbjct: 419 EQKEQMRKQEEHMGEQKE 436



 Score =  182 bits (461), Expect = 3e-46
 Identities = 101/196 (51%), Positives = 154/196 (78%), Gaps = 10/196 (5%)

Query: 1   MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
           +RE+E ++RE+E ++RE+E  +REQE +++EQE ++REQE ++ EQE +++EQE +M EQ
Sbjct: 138 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQ 197

Query: 60  EEKMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
           E +M EQEE+M EQ +++ +Q+E+M EQ+E++R++EE+M EQ+  +QV+K  E+ + QEE
Sbjct: 198 EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE--EQVQKQEEQVQKQEE 255

Query: 119 KMQEQEEKMQEQEEMMWEQEEKM------QEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 172
           +M++QEE+M+EQEE M EQEE+M       EQEE+  EQEE+MREQEE+MREQEE+M+ Q
Sbjct: 256 QMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQ 315

Query: 173 EEKMRDVEPAGGEAGE 188
           EE+MR+ E   G+  E
Sbjct: 316 EEQMREQEEQMGKQEE 331



 Score =  177 bits (450), Expect = 5e-45
 Identities = 97/184 (52%), Positives = 148/184 (80%), Gaps = 10/184 (5%)

Query: 1   MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
           +RE+E ++RE+E ++RE+E  +REQE +++EQE ++REQE +M EQE +M EQEE+M EQ
Sbjct: 152 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQ 211

Query: 60  EEKMWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
           EE+M +QEE+M EQ +++ +Q+E+M EQ+E+++++EE++++Q+  +Q+ K  E+ + QEE
Sbjct: 212 EEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQE--EQMRKQEEQMREQEE 269

Query: 119 KMQEQEEKM------QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 172
           +M+EQEE+M       EQEE   EQEE+M+EQEE+M EQEE+MREQEE+MREQEE+M  Q
Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ 329

Query: 173 EEKM 176
           EE+M
Sbjct: 330 EEQM 333



 Score =  162 bits (410), Expect = 2e-40
 Identities = 90/205 (43%), Positives = 152/205 (74%), Gaps = 4/205 (1%)

Query: 1   MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
           +RE+E ++RE+E ++RE+E  +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ
Sbjct: 110 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 169

Query: 60  EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
           E ++ EQE ++ EQ+ ++ EQ+ +M EQ+ ++ E+EE+M EQ+  +Q++K  E+   QEE
Sbjct: 170 EGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE--EQMQKQEEQMGEQEE 227

Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
           +M++QEE+M EQEE + +QEE++Q+QEE+M +QEE+MREQEE+MREQEE+M  Q+E+   
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ 287

Query: 179 VEPAGGEAGEGSPQDNPTAQEIMQL 203
            E  G +  +   Q+    ++  Q+
Sbjct: 288 EEQTGEQEEQMREQEEQMREQEEQM 312



 Score =  159 bits (403), Expect = 2e-39
 Identities = 93/207 (44%), Positives = 156/207 (75%), Gaps = 8/207 (3%)

Query: 1   MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
           +RE+E ++RE+E ++RE+E  +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ
Sbjct: 96  VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 155

Query: 60  EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKTQ 116
           E ++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E +M EQ+  M +Q E+M E    Q
Sbjct: 156 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGE----Q 211

Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
           EE+MQ+QEE+M EQEE M +QEE+M EQEE++ +QEE++++QEE+MR+QEE+M+ QEE+M
Sbjct: 212 EEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQM 271

Query: 177 RDVEPAGGEAGEGSPQDNPTAQEIMQL 203
           R+ E    +  E + Q+  T ++  Q+
Sbjct: 272 REQEEQMLKQKEQTEQEEQTGEQEEQM 298



 Score =  156 bits (395), Expect = 1e-38
 Identities = 94/204 (46%), Positives = 153/204 (75%), Gaps = 9/204 (4%)

Query: 1   MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
           +RE+E ++RE+E ++RE+E  +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ
Sbjct: 89  VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 148

Query: 60  EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKTQ 116
           E ++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E ++REQ+  M +Q  +M E    Q
Sbjct: 149 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGE----Q 204

Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
           EE+M EQEE+MQ+QEE M EQEE+M++QEE+M EQEE++++QEE++++QEE+M+ QEE+M
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264

Query: 177 RDVEPAGGEAGEGS-PQDNPTAQE 199
           R+ E    E  E    Q   T QE
Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQE 288



 Score =  154 bits (389), Expect = 6e-38
 Identities = 87/182 (47%), Positives = 141/182 (77%), Gaps = 4/182 (2%)

Query: 1   MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
           +RE+E ++RE+E ++RE+E  +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ
Sbjct: 75  VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 134

Query: 60  EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
           E ++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E ++REQ+   QV +   + + QE 
Sbjct: 135 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEG 192

Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
           +M EQE +M EQEE M EQEE+MQ+QEE+M EQEE+MR+QEE+M EQEE++Q QEE+++ 
Sbjct: 193 QMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQK 252

Query: 179 VE 180
            E
Sbjct: 253 QE 254



 Score =  147 bits (370), Expect = 1e-35
 Identities = 83/182 (45%), Positives = 140/182 (76%), Gaps = 4/182 (2%)

Query: 1   MREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
           +RE+E ++RE+E ++RE+E  +REQE +++EQE ++REQE ++ EQE +++EQE ++ EQ
Sbjct: 61  VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 120

Query: 60  EEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
           E ++ EQE ++ EQ+ ++ EQ+ ++ EQ+ ++RE+E ++REQ+   QV +   + + QE 
Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEG 178

Query: 119 KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
           +++EQE +++EQE  M EQE +M EQEE+M EQEE+M++QEE+M EQEE+M+ QEE+M +
Sbjct: 179 QVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE 238

Query: 179 VE 180
            E
Sbjct: 239 QE 240



 Score = 85.5 bits (210), Expect = 4e-17
 Identities = 50/152 (32%), Positives = 101/152 (66%), Gaps = 2/152 (1%)

Query: 29  QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDE 88
           +E +EK  E +E++   E +  E +  + E + K+   +  + ++ ++ EQ+ ++ EQ+ 
Sbjct: 7   EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66

Query: 89  RLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKM 148
           ++RE+E ++REQ+   QV +   + + QE +++EQE +++EQE  + EQE +++EQE ++
Sbjct: 67  QVREQEGQVREQE--GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 124

Query: 149 WEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
            EQE ++REQE ++REQE +++ QE ++R+ E
Sbjct: 125 REQEGQVREQEGQVREQEGQVREQEGQVREQE 156


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score =  172 bits (437), Expect = 2e-43
 Identities = 96/210 (45%), Positives = 151/210 (71%), Gaps = 35/210 (16%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+EER+RE+E+++RE+EE +REQEE++ EQEE++REQEE++ EQEE++ EQEE++ E EE
Sbjct: 196 RQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEE 255

Query: 62  KMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEE 118
           ++ EQEE++ EQ+ RL EQ+E++ EQ+ERL E+EER+REQ  ++ +Q E++RE    QEE
Sbjct: 256 RLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLRE----QEE 311

Query: 119 KMQEQEEKMQEQEEMMWEQE-----EKMQEQEEKMWEQEEKMREQE-------------- 159
           ++ EQEE+++EQEE + EQE     E++ E+ EK+ EQE +  EQE              
Sbjct: 312 RLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEE 371

Query: 160 ----EKMREQEEKMQGQE-----EKMRDVE 180
               E++R+Q+E++  QE     E++R++E
Sbjct: 372 LLEQERLRQQDERLWQQETLQELERLRELE 401



 Score =  168 bits (426), Expect = 3e-42
 Identities = 87/173 (50%), Positives = 131/173 (75%), Gaps = 23/173 (13%)

Query: 8   REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67
           R +E+++RE+EE +REQEE+++EQEE++ EQEE++ EQEE+++EQEE++ EQEE++ E E
Sbjct: 195 RRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHE 254

Query: 68  EKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKM 127
           E      RL EQ+E++ EQ+ERLRE+EER+ E                QEE++ EQEE++
Sbjct: 255 E------RLCEQEERLCEQEERLREQEERLHE----------------QEERLCEQEERL 292

Query: 128 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
           +EQEE + EQEE+++EQEE++ EQEE++REQEE++ EQ EK+ GQE  + +VE
Sbjct: 293 REQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ-EKLPGQERLLEEVE 344



 Score =  142 bits (357), Expect = 3e-34
 Identities = 82/236 (34%), Positives = 148/236 (62%), Gaps = 27/236 (11%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
           +EER+ E+E+++RE+EE + EQEE++ EQEE++REQEE++ EQEE+++EQEE++ EQEE+
Sbjct: 260 QEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEER 319

Query: 63  MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQE 122
           + EQEE++ EQ++LP Q E++ E+ E+L E+E R  EQ+   + E++ E    + E++ E
Sbjct: 320 LREQEERLCEQEKLPGQ-ERLLEEVEKLLEQERRQEEQERLLERERLLE----EVEELLE 374

Query: 123 QEEKMQEQEEMMWEQE-----EKMQEQE-------EKMWEQEEKMREQEEKMREQEEKMQ 170
           Q E++++Q+E +W+QE     E+++E E       E ++EQ  + R   E++  + +   
Sbjct: 375 Q-ERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTL 433

Query: 171 GQEEKMRDVEPAGGEAGEGSPQDNPTAQEIM-------QLFCGMK--NAQQCPGLG 217
             E+++++++ +GG       +    A+ +           CG      Q+ PGLG
Sbjct: 434 QLEQQVKELKKSGGAEEPRGSESAAAARPVAGAPVPQGAWMCGQAGWTPQEHPGLG 489



 Score =  120 bits (301), Expect = 1e-27
 Identities = 70/185 (37%), Positives = 115/185 (62%), Gaps = 21/185 (11%)

Query: 26  EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW----EQEEKMWEQEEKMWEQQ-RLPEQK 80
           E++Q++   +R++ E +  Q +   E  + +      QEE++ EQEE++ EQ+ RL EQ+
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQE 219

Query: 81  EKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEK 140
           E++ EQ+ERLRE+EER+REQ                EE++ EQEE+++E EE + EQEE+
Sbjct: 220 ERLCEQEERLREQEERLREQ----------------EERLCEQEERLREHEERLCEQEER 263

Query: 141 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEI 200
           + EQEE++ EQEE++ EQEE++ EQEE+++ QEE++ + E    E  E   +     +E 
Sbjct: 264 LCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQ 323

Query: 201 MQLFC 205
            +  C
Sbjct: 324 EERLC 328



 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 60/196 (30%), Positives = 107/196 (54%), Gaps = 17/196 (8%)

Query: 3   EEERMREREKKMREEEEMMREQEE------KMQEQEEKMREQEEKMWEQEEKMQEQEEKM 56
           +EER+RE+E+++ E+EE +REQEE      K+  Q E++ E+ EK+ EQE + +EQE  +
Sbjct: 302 QEERLREQEERLCEQEERLREQEERLCEQEKLPGQ-ERLLEEVEKLLEQERRQEEQERLL 360

Query: 57  WEQEEKMWEQEEKMWEQQRLPEQKEKMWEQD-----ERLREKEERMREQKMWQQVEKMRE 111
             + E++ E+ E++ EQ+RL +Q E++W+Q+     ERLRE E  +  +  W+ + + R 
Sbjct: 361 --ERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERML--ELGWEALYEQRA 416

Query: 112 KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG 171
           + ++  E++  + +   + E+ + E ++    +E +  E     R        Q   M G
Sbjct: 417 EPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPRGSESAAAARPVAGAPVPQGAWMCG 476

Query: 172 QEEKMRDVEPA-GGEA 186
           Q        P  GGEA
Sbjct: 477 QAGWTPQEHPGLGGEA 492



 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 30/116 (25%), Positives = 69/116 (59%), Gaps = 9/116 (7%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQE-----QEEKMREQEEKMWEQEEKMQEQEEK 55
           + E E++ E+E++  EE+E + E+E  ++E     ++E++R+Q+E++W+QE    ++ E+
Sbjct: 340 LEEVEKLLEQERRQ-EEQERLLERERLLEEVEELLEQERLRQQDERLWQQE--TLQELER 396

Query: 56  MWEQEEKMWEQEEKMWEQQRLPEQK-EKMWEQDERLREKEERMREQKMWQQVEKMR 110
           + E E  +    E ++EQ+  P    E++  +++   + E++++E K     E+ R
Sbjct: 397 LRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPR 452



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 32/125 (25%), Positives = 60/125 (48%), Gaps = 12/125 (9%)

Query: 93  KEERMREQKMWQQVEKMREKKKTQEEKMQEQE--------EKMQEQEEMMWEQEEKMQEQ 144
           KEE+  E  + Q++ +   K K Q  +    E        E++Q++   + ++ E +  Q
Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179

Query: 145 EEKMWEQEEKM----REQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEI 200
            +   E  + +    R QEE++REQEE+++ QEE++R+ E    E  E   +     +E 
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQ 239

Query: 201 MQLFC 205
            +  C
Sbjct: 240 EERLC 244


>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 479

 Score =  140 bits (352), Expect = 1e-33
 Identities = 76/191 (39%), Positives = 135/191 (70%), Gaps = 22/191 (11%)

Query: 8   REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67
           R +E+++RE+EE + EQEE++ EQEE++ EQEE++ EQEE+++EQEE++ EQEE++ EQE
Sbjct: 195 RRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQE 254

Query: 68  EKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE--EKMQEQEE 125
           E      RL EQ+E++ EQ+ERL E+E+   ++++ ++VEK+ E+++ QE  E++ E+E 
Sbjct: 255 E------RLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERER 308

Query: 126 KMQEQEEMMWEQEEKMQEQEEKMWEQE-----EKMREQE-----EKMREQEEKMQGQEEK 175
            + E EE++  ++E++++Q+E++W+QE     E++RE E     E++RE E  ++   E 
Sbjct: 309 LLDEVEELL--EQERLRQQDERLWQQETLRELERLRELERLRELERLRELERMLELGWEA 366

Query: 176 MRD--VEPAGG 184
           + +   EP  G
Sbjct: 367 LYEQRAEPRSG 377



 Score =  135 bits (341), Expect = 2e-32
 Identities = 71/200 (35%), Positives = 133/200 (66%), Gaps = 18/200 (9%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
           +EER+ E+E+++ E+EE + EQEE++ EQEE++REQEE++ EQEE++ EQEE++ EQEE+
Sbjct: 204 QEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEER 263

Query: 63  MWEQEEKMWEQQRLP------EQKEKMWEQDERLREKEERMREQKMWQQVEKM--REKKK 114
           + EQEE++ EQ++LP      E+ EK+ EQ+ R  E+E  +  +++  +VE++  +E+ +
Sbjct: 264 LCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQERLR 323

Query: 115 TQEEKMQEQE-----EKMQEQE-----EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164
            Q+E++ +QE     E+++E E     E + E E  ++   E ++EQ  + R   E++  
Sbjct: 324 QQDERLWQQETLRELERLRELERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNN 383

Query: 165 QEEKMQGQEEKMRDVEPAGG 184
           + +     E++++++E +GG
Sbjct: 384 ENKSTLQLEQQVKELEKSGG 403



 Score =  120 bits (301), Expect = 1e-27
 Identities = 69/184 (37%), Positives = 129/184 (70%), Gaps = 12/184 (6%)

Query: 5   ERMREREKKMREEEEMMREQEEKMQEQEEKM----REQEEKMWEQEEKMQEQEEKMWEQE 60
           E++++    +R+E E +  Q +   E  + +    R QEE++ EQEE++ EQEE++ EQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQE 219

Query: 61  EKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERM--REQKMWQQVEKMREKKKTQ- 116
           E++ EQEE++ EQ+ RL EQ+E++ EQ+ERL E+EER+  +E+++ +Q E++ E++K   
Sbjct: 220 ERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPG 279

Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
           +E++ E+ EK+ EQE    E++E++ E+E  + E EE +  ++E++R+Q+E++  Q+E +
Sbjct: 280 QERLLEEVEKLLEQERRQ-EEQERLLERERLLDEVEELL--EQERLRQQDERL-WQQETL 335

Query: 177 RDVE 180
           R++E
Sbjct: 336 RELE 339



 Score = 92.0 bits (227), Expect = 4e-19
 Identities = 51/139 (36%), Positives = 86/139 (61%), Gaps = 18/139 (12%)

Query: 47  EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQV 106
           E++Q++   + ++ E +  Q +   E  ++     +   Q+ERLRE+EER+ EQ      
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR--RQEERLREQEERLHEQ------ 211

Query: 107 EKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 166
                     EE++ EQEE++ EQEE + EQEE+++EQEE++ EQEE++ EQEE++ EQE
Sbjct: 212 ----------EERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQE 261

Query: 167 EKMQGQEEKMRDVEPAGGE 185
           E++  QEE++ + E   G+
Sbjct: 262 ERLCEQEERLCEQEKLPGQ 280



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 36/147 (24%), Positives = 79/147 (53%), Gaps = 22/147 (14%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
           + E E++ E+E++  EE+E + E+E  + E EE +         ++E++++Q+E++W+QE
Sbjct: 284 LEEVEKLLEQERRQ-EEQERLLERERLLDEVEELL---------EQERLRQQDERLWQQE 333

Query: 61  EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
                + E++ E +RL E         ERLRE E  +  +  W+ + + R + ++  E++
Sbjct: 334 --TLRELERLRELERLREL--------ERLRELERML--ELGWEALYEQRAEPRSGFEEL 381

Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEK 147
             + +   + E+ + E E+    +E +
Sbjct: 382 NNENKSTLQLEQQVKELEKSGGAEEPR 408



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 27/101 (26%), Positives = 54/101 (53%)

Query: 105 QVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164
           +VE+++++     ++++    ++Q + E         + QEE++ EQEE++ EQEE++ E
Sbjct: 158 KVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHE 217

Query: 165 QEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEIMQLFC 205
           QEE++  QEE++ + E    E  E   +      E  +  C
Sbjct: 218 QEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLC 258



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 27/100 (27%), Positives = 51/100 (51%), Gaps = 12/100 (12%)

Query: 93  KEERMREQKMWQQVEKMREKKKTQEEKMQEQE--------EKMQEQEEMMWEQEEKMQEQ 144
           KEE+  E  + Q++ +   K K Q  +    E        E++Q++   + ++ E +  Q
Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179

Query: 145 EEKMWEQEEKM----REQEEKMREQEEKMQGQEEKMRDVE 180
            +   E  + +    R QEE++REQEE++  QEE++ + E
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQE 219


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score =  123 bits (308), Expect = 2e-28
 Identities = 60/179 (33%), Positives = 124/179 (69%), Gaps = 6/179 (3%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKMQEQEEKMWEQE 60
            RE+ R++ERE++ REEEE+ +E+E+ + E+ E  R QE E+ + +EE++Q++EE++  +E
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097

Query: 61   EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
             +   ++E+   +++  E++E   E+++ LRE+ E+ R Q++ +Q  +  E ++ +E+ +
Sbjct: 1098 PEKRRRQER---ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLL 1154

Query: 121  QEQEEKMQEQE-EMMWEQEEKMQEQEEKMW-EQEEKMREQEEKMREQEEKMQGQEEKMR 177
            +E+ EK + QE E  + +EE++Q++EE++  E++EK R++ E+   +EE++Q Q+ K R
Sbjct: 1155 REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213



 Score =  119 bits (299), Expect = 2e-27
 Identities = 62/184 (33%), Positives = 123/184 (66%), Gaps = 7/184 (3%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKMQEQEEKMWEQE 60
            RE+ R +E+E++ REEE++ +E+E+ ++E+ EK R QE E+ + +++K+Q++EE++  +E
Sbjct: 918  REKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977

Query: 61   EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
             +   ++E+   +++  E++E   E+++ LRE+ E+ R Q+  +Q  K  E ++ +E+ +
Sbjct: 978  PEKRRRQER---EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034

Query: 121  QEQEEK--MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE-EKMREQEEKMQGQEEKMR 177
            +E+ EK  +QE+E    E+EE  QE+E+ + E+ E  R QE E+   +EE++Q +EE++ 
Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094

Query: 178  DVEP 181
              EP
Sbjct: 1095 REEP 1098



 Score =  119 bits (299), Expect = 2e-27
 Identities = 64/183 (34%), Positives = 120/183 (65%), Gaps = 7/183 (3%)

Query: 3    EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKMQEQEEKMWEQEE 61
            E+ R +EREKK REEEE+ +E+E+ ++E+ EK R QE E+ + +++++Q++EE++  +E 
Sbjct: 979  EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER 1038

Query: 62   KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121
            +    +E+   +++  E++E   E+++ L E+ E  R Q++ +Q  K  E ++ +E+ ++
Sbjct: 1039 EKRRLQER---ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR 1095

Query: 122  EQEEK--MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE-EKMREQEEKMQGQEEKMRD 178
            E+ EK   QE+E    E+EE  QE+E+ + E+ EK R QE E+   +EE++Q +EE++  
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155

Query: 179  VEP 181
             EP
Sbjct: 1156 EEP 1158



 Score =  113 bits (282), Expect = 2e-25
 Identities = 62/196 (31%), Positives = 130/196 (66%), Gaps = 17/196 (8%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKMQEQEEKMWEQE 60
            RE+ R +E E++ R+++E+ +E+E+ ++E+ EK R QE E+ + +EE++Q++EE++  +E
Sbjct: 1008 REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEE 1067

Query: 61   ---------EKMWEQEEKMW--EQQRLPEQKEKM--WEQDERLREKEERMREQKMWQQVE 107
                     E+ + +EE++   E+Q L E+ EK    E++ + RE+EE  +E++   + E
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127

Query: 108  KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQE-EKMWEQEEKMREQEEKM--RE 164
            + + +++  E + +E+EE  QE+E+++ E+ EK + QE E+ + +EE+++++EE++   E
Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187

Query: 165  QEEKMQGQEEKMRDVE 180
            QE++ Q +E + R+ E
Sbjct: 1188 QEKRRQERERQYREEE 1203



 Score =  109 bits (273), Expect = 2e-24
 Identities = 59/189 (31%), Positives = 120/189 (63%), Gaps = 17/189 (8%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKMQEQEEKMW--E 58
            RE+ R +E E++ REEEE+ +E+E+ ++E+ EK R QE E+ + +EE++Q++EE++   E
Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187

Query: 59   QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLR---------EKEERMREQKMWQQVEKM 109
            QE++  E+E +  E++ L  QK K   +DE  R         EKE  +R+ K++ +  + 
Sbjct: 1188 QEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGREN 1247

Query: 110  REKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 169
             + ++ ++ ++++++ + Q+ + ++ EQ+E+ +EQE + W+Q ++   +EE++  +E+K 
Sbjct: 1248 EQFRQLEDSQLRDRQSQ-QDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQK- 1305

Query: 170  QGQEEKMRD 178
               E K RD
Sbjct: 1306 ---EAKRRD 1311



 Score =  108 bits (270), Expect = 4e-24
 Identities = 56/193 (29%), Positives = 132/193 (68%), Gaps = 18/193 (9%)

Query: 3    EEERMRER---------EKKMREEEEMMREQEEKMQ--EQEEKMREQEEKMWEQEEKMQE 51
            EEER R R         ++++R+E+++++E+EE++Q  E+E++ R+++E+ + +EE++Q+
Sbjct: 879  EEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQ 938

Query: 52   QEEKMW--EQEEKMWEQEEKMWEQQRLPEQKEK--MWEQDERLR--EKEERMREQKMWQQ 105
            +EE++   E+E++  ++ E+ + + +  +QKE+  + E+ E+ R  E+E++ RE++  QQ
Sbjct: 939  EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998

Query: 106  VEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQE-EKMREQEEKMRE 164
             E+   +++ ++ + QE E + ++++E+  E+E+ ++E+ EK   QE E+   +EE++++
Sbjct: 999  EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ 1058

Query: 165  QEEKMQGQEEKMR 177
            +EE++ G+E + R
Sbjct: 1059 EEEQLLGEERETR 1071



 Score =  108 bits (269), Expect = 5e-24
 Identities = 62/199 (31%), Positives = 126/199 (63%), Gaps = 22/199 (11%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ---EEKMWE 58
           RE +   ++++++R E+++ R+QEE+ +EQ+E+ REQ+E+  +QEE+ ++Q   E++   
Sbjct: 288 RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR 347

Query: 59  QEEKMWEQEEKMWEQQRLPEQKEKMWEQ----------DERLREKEERMREQKMWQQVEK 108
           +++   EQEE+  EQQ   EQ+E+  EQ          +++LR +++  REQ++ ++ + 
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 407

Query: 109 MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKM-WEQEEK----MREQEEKMR 163
            RE++  +E++++ +++  +EQEE   EQ+ + + +E+++  EQEE+     RE+E +  
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467

Query: 164 EQEEKMQ----GQEEKMRD 178
           EQE + Q     QEE+ R+
Sbjct: 468 EQERRKQQLKRDQEEERRE 486



 Score =  107 bits (267), Expect = 9e-24
 Identities = 56/184 (30%), Positives = 123/184 (66%), Gaps = 9/184 (4%)

Query: 3   EEERMREREKK-MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           EEE++R+ E++ +R E +   +Q+++++ +++  R+QEE+  EQ+E+ +EQ+E+  +QEE
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333

Query: 62  KMWEQ----EEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE 117
           +  +Q    +E+  EQQ   EQ+E+  EQ  R RE+EE  REQ++ ++ +  RE++  +E
Sbjct: 334 RREQQLRREQEERREQQLRREQEEERREQQLR-REQEEERREQQLRREQQLRREQQLRRE 392

Query: 118 EKMQEQEEKMQEQE---EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 174
           ++++ +++  +EQ+   E    +E++++ +++   EQEE+  EQ+ +   +E++++ ++E
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452

Query: 175 KMRD 178
           + RD
Sbjct: 453 ERRD 456



 Score =  105 bits (263), Expect = 3e-23
 Identities = 56/190 (29%), Positives = 119/190 (62%), Gaps = 14/190 (7%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKMQEQEEKMWEQE 60
            RE  R +E E++ R+EEE+ +E+E+ ++E+ EK R QE E+   +EE++Q++EE++  +E
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127

Query: 61   EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
             +   ++E    +++  E++E   E+++ LRE+ E+ R Q++ +Q  +  E ++ +E+ +
Sbjct: 1128 REKRRRQEL---ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL 1184

Query: 121  QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR---------EQEEKMREQEEKMQG 171
            +E++EK +++ E  + +EE++Q Q+ K   ++E  R         E+E  +R+ +   +G
Sbjct: 1185 REEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKG 1244

Query: 172  QE-EKMRDVE 180
            +E E+ R +E
Sbjct: 1245 RENEQFRQLE 1254



 Score =  103 bits (258), Expect = 1e-22
 Identities = 59/184 (32%), Positives = 119/184 (64%), Gaps = 13/184 (7%)

Query: 1   MREEERMREREKKMREEE-------EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 53
           ++EEE  R+RE +  EE+       E+ RE++E+ Q+Q+   REQ+ +  ++EE+ ++QE
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319

Query: 54  EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113
           E+  +QE +  EQ+E+  EQQ   EQ+E+  EQ  R RE+EE  REQ++ ++ E+ R ++
Sbjct: 320 ERREQQERR--EQQEERREQQLRREQEERR-EQQLR-REQEEERREQQLRREQEEERREQ 375

Query: 114 KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ--EEKMWEQEEKMREQEEKMREQEEKMQG 171
           + + E+   +E++++ ++++  EQ+ + ++Q   E+   +E+++R +++  REQEE+   
Sbjct: 376 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435

Query: 172 QEEK 175
           Q+ +
Sbjct: 436 QKHE 439



 Score =  103 bits (258), Expect = 1e-22
 Identities = 59/207 (28%), Positives = 127/207 (61%), Gaps = 20/207 (9%)

Query: 2    REEERMREREKKMREEEEMMREQEEKM---QEQEEKMREQEEKM--WEQEEKMQEQEEKM 56
            RE++   +R++K REEE++++E EE+    QE++ K RE+E+++   E+E K  ++E+++
Sbjct: 1657 REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQL 1716

Query: 57   WEQE-EKMWEQEEKM-----WEQQRLPEQKEKMWEQDERLREKEE----RMREQKMWQQV 106
              QE E+ + +EE++      EQ R  E+  K+ E+++   E+EE    R    + +++ 
Sbjct: 1717 RRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776

Query: 107  EKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEK----MWEQEE-KMREQEEK 161
            E++R++++ Q+ + QE + K +E+E++  E+EE+    +++     WE+E+ ++ EQE++
Sbjct: 1777 EQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836

Query: 162  MREQEEKMQGQEEKMRDVEPAGGEAGE 188
            +R++ ++    EE+    E +  E  E
Sbjct: 1837 LRQERDRQYRAEEQFATQEKSRREEQE 1863



 Score =  103 bits (257), Expect = 1e-22
 Identities = 60/199 (30%), Positives = 121/199 (60%), Gaps = 26/199 (13%)

Query: 2   REEERMREREKKMREEEEMM----REQEEKMQEQEEKMRE--------QEEKMWEQEEKM 49
           R+ +  +ERE++  EEE++      E EE   E++ + RE        +EEK  ++ E+ 
Sbjct: 175 RQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQ 234

Query: 50  ----QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKE------ERMRE 99
               QE+EEK W + E +  +EE+  +++  P+++ ++ E++E+LR+ E      ER  E
Sbjct: 235 DRVFQEEEEKEWRKRETVLRKEEEKLQEEE-PQRQRELQEEEEQLRKLERQELRRERQEE 293

Query: 100 QKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ---EEKMWEQEEKMR 156
           ++  Q++ + ++ ++ QEE+ +EQ+E+ +EQ+E   +QEE+ ++Q   E++   +++  R
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353

Query: 157 EQEEKMREQEEKMQGQEEK 175
           EQEE+ REQ+ + + +EE+
Sbjct: 354 EQEEERREQQLRREQEEER 372



 Score =  103 bits (257), Expect = 1e-22
 Identities = 70/202 (34%), Positives = 124/202 (61%), Gaps = 28/202 (13%)

Query: 2    REEERMR-EREKKMREEEEMMREQEE---KMQEQEEKMREQE-------EKMWEQEEKM- 49
            REE+R R E ++K REEE++++E+EE   + QE++ K RE+E        K  E+E+++ 
Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLR 1384

Query: 50   -QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERL--REKEERMREQKMWQQV 106
             QE+E K  ++E+++  QE    EQQ   ++  K  E++++L  +E++ + RE++  QQV
Sbjct: 1385 RQERERKFLKEEQQLRCQER---EQQLRQDRDRKFREEEQQLSRQERDRKFREEE--QQV 1439

Query: 107  EKMREKKKTQEEKM---QEQEEKMQEQEEMMWEQEEKM---QEQEEKMWEQEEKMREQE- 159
             +   ++K  EE+    QE+  K +E+E+++ E+EE+    QE++ K  E+E+++R QE 
Sbjct: 1440 RRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQER 1499

Query: 160  -EKMREQEEKMQGQEEKMRDVE 180
              K REQE + Q  E K  + E
Sbjct: 1500 DRKFREQELRSQEPERKFLEEE 1521



 Score =  103 bits (256), Expect = 2e-22
 Identities = 64/207 (30%), Positives = 123/207 (59%), Gaps = 19/207 (9%)

Query: 1    MREEERMR-EREKKMREEEEMMREQEEKM---QEQEEKMREQEEKMWEQE--EKMQEQEE 54
            + EE+++R ER +K REEE++++E+EE+    QE++ K  E+E+++  QE   K +EQE 
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL 1508

Query: 55   KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKE----ERMREQKMWQQVEKMR 110
            +  E E K  E+E+++  QQR    + K  +++++LR +E     R    + +++ E++R
Sbjct: 1509 RSQEPERKFLEEEQQLHRQQR----QRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLR 1564

Query: 111  EKKKTQEEKMQEQEEK--MQEQEEMMWEQEEKMQEQEEKMWEQE---EKMREQEEKMREQ 165
            ++++ Q+   QE++ K  ++EQ+    EQE K  E E+++  QE   +  +E++ K RE 
Sbjct: 1565 QEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRED 1624

Query: 166  EEKMQGQEEKMRDVEPAGGEAGEGSPQ 192
            E+ +Q +EE+    +    +  E  PQ
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQ 1651



 Score =  102 bits (253), Expect = 4e-22
 Identities = 61/193 (31%), Positives = 121/193 (62%), Gaps = 21/193 (10%)

Query: 3   EEERMREREKKMREEEEMMREQE----EKMQEQEEKMRE---QEEKMWEQEEKMQEQ--- 52
           EE+  R+RE  +R+EEE ++E+E     ++QE+EE++R+   QE +   QEE+ Q+Q   
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR 301

Query: 53  --EEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR 110
             ++   +QEE+  EQ+E+  EQQ   EQ+E+  EQ  R RE+EER  +Q   +Q E+ R
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQQEERREQQLR-REQEERREQQLRREQEEERR 360

Query: 111 EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ--------EEKMWEQEEKMREQEEKM 162
           E++  +E++ + +E++++ ++++  EQ+ + ++Q         E+   +E+++R +++  
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420

Query: 163 REQEEKMQGQEEK 175
           REQ+ + + +EE+
Sbjct: 421 REQQLRREQEEER 433



 Score =  102 bits (253), Expect = 4e-22
 Identities = 61/203 (30%), Positives = 121/203 (59%), Gaps = 27/203 (13%)

Query: 2    REEERM---REREKKMREEEEMMREQEEK----------MQEQEEKMREQEEKMWEQEEK 48
            REEE+    +ER++K REEE+ +R QE +           QE+  K RE+E+ + E+EE+
Sbjct: 1417 REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1476

Query: 49   M---QEQEEKMWEQEEKMWEQE--EKMWEQQRLPEQKEKMWEQDERLREKEERMR----E 99
                QE++ K  E+E+++  QE   K  EQ+   ++ E+ + ++E+   +++R R    E
Sbjct: 1477 QLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQE 1536

Query: 100  QKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE-----KMQEQEEKMWEQEEK 154
            ++  ++ E+ +++++ ++ K +E+E+  QE+EE    ++E     +++EQ+ +  EQE K
Sbjct: 1537 EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK 1596

Query: 155  MREQEEKMREQEEKMQGQEEKMR 177
              E E+++R QE + Q ++E+ R
Sbjct: 1597 FMEDEQQLRRQEGQQQLRQERDR 1619



 Score =  101 bits (252), Expect = 5e-22
 Identities = 66/206 (32%), Positives = 122/206 (59%), Gaps = 31/206 (15%)

Query: 1   MREEERMREREKKMREEEEMMR--EQEEKMQEQEEKMREQ-EEKMWEQEEKMQEQEEKMW 57
           + EE   R R+K+  +E E+    EQ EK +  E++ R++ +E++W Q ++ QE+EE+  
Sbjct: 129 LEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRA 188

Query: 58  EQEE----KMWEQEEKMWEQQ-------------RLPEQKEKMWEQDERLREKEE---RM 97
           E+E+    K  E EE   E+Q             R  +Q+++   QD   +E+EE   R 
Sbjct: 189 EEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRK 248

Query: 98  REQKMWQQVEKMREKKKTQEEKMQEQEEKMQ--EQEEMMWEQEEKMQEQEEKMWE----- 150
           RE  + ++ EK++E++  ++ ++QE+EE+++  E++E+  E++E+ Q+Q+    E     
Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308

Query: 151 -QEEKMREQEEKMREQEEKMQGQEEK 175
            QEE+ REQ+E+ REQ+E+ + QEE+
Sbjct: 309 KQEEERREQQEERREQQERREQQEER 334



 Score =  101 bits (252), Expect = 5e-22
 Identities = 50/189 (26%), Positives = 120/189 (63%), Gaps = 13/189 (6%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE--EKMWEQ 59
           + E ++R  E++ RE+  +  E+E++ + ++ + RE+E +  E+EE++Q +E  +++ E+
Sbjct: 793 QRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEE 852

Query: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK----------EERMREQKMWQQVEKM 109
           E+ + E +E+   Q++  +QK +   ++ER R +          E+  +EQ++ Q+ E+ 
Sbjct: 853 EDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE 912

Query: 110 REKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQE-EKMREQEEKMREQEEK 168
            ++++ ++ + QEQE + +E+E++  E+E+ ++E+ EK   QE E+   +++K++++EE+
Sbjct: 913 LQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972

Query: 169 MQGQEEKMR 177
           + G+E + R
Sbjct: 973 LLGEEPEKR 981



 Score =  101 bits (251), Expect = 6e-22
 Identities = 53/175 (30%), Positives = 115/175 (65%), Gaps = 7/175 (4%)

Query: 9   EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 68
           E EK+ R+ E ++R++EEK+QE+E + + + ++  EQ  K++ QE +   QEE+  +Q+ 
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQ-QQQR 299

Query: 69  KMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQ 128
              EQQ   +Q+E+  EQ E  RE++ER  +Q+  ++ +  RE+++ +E++++ ++E+ +
Sbjct: 300 LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359

Query: 129 EQEEMMWEQEEKMQEQE---EKMWEQEEKMREQEEKMREQE---EKMQGQEEKMR 177
            ++++  EQEE+ +EQ+   E+   +E+++R +++  REQ+   E+   +E+++R
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 414



 Score =  101 bits (251), Expect = 6e-22
 Identities = 60/199 (30%), Positives = 125/199 (62%), Gaps = 23/199 (11%)

Query: 1   MREEERMREREKKMREEEEMMREQ----EEKMQEQEEKMREQEEKMWEQ--EEKMQEQEE 54
           +R E+++R RE+++R E+++ REQ    E++++ +++  REQEE+  EQ  E++ +EQ  
Sbjct: 389 LRREQQLR-REQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447

Query: 55  KMWEQEEKMW---EQEEKMWEQQRLPEQKEKMWEQDER-----LREKEERMREQKMWQQV 106
           K  ++E + W   E+E +  EQ+R  +Q ++  E++ R     L E+E R ++++  QQ+
Sbjct: 448 KREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQL 507

Query: 107 EKMREKKKTQEEKMQEQEEKMQE----QEEMMWEQEEK----MQEQEEKMWEQEEKMREQ 158
            + +E+++ Q  K QE+EE++Q+    ++++  EQEE+    ++ +EEK  EQE + +  
Sbjct: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567

Query: 159 EEKMREQEEKMQGQEEKMR 177
           + +  E+ +++  +EE+ R
Sbjct: 568 KREQEERRDQLLKREEERR 586



 Score =  101 bits (251), Expect = 6e-22
 Identities = 57/202 (28%), Positives = 128/202 (63%), Gaps = 25/202 (12%)

Query: 2    REEERMREREKKMREEEEMMREQEE------------KMQEQEEKMREQEEKMWEQEEKM 49
            R ++R ++R++K REEE++ +E+EE            +++EQ+ + +EQE K  E E+++
Sbjct: 1545 RGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQL 1604

Query: 50   QEQE--EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVE 107
            + QE  +++ ++ ++ + ++E++ +++   EQ+    E+D +  E+E ++R Q+  QQ+ 
Sbjct: 1605 RRQEGQQQLRQERDRKFREDEQLLQERE--EQQLHRQERDRKFLEEEPQLRRQEREQQLR 1662

Query: 108  KMREKKKTQEEKM----QEQEEKMQEQEEMMWEQEEKM--QEQEEKMWEQEEKMREQ--E 159
              R++K  +EE++    +EQ+ + QE++    E+E+++  QE+E K  ++E+++R Q  E
Sbjct: 1663 HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELE 1722

Query: 160  EKMREQEE-KMQGQEEKMRDVE 180
             K RE+E+ + + ++E++R  E
Sbjct: 1723 RKFREEEQLRQETEQEQLRRQE 1744



 Score =  100 bits (249), Expect = 1e-21
 Identities = 55/186 (29%), Positives = 120/186 (64%), Gaps = 10/186 (5%)

Query: 2   REEERMREREKKMR----EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 57
           REE++ + RE++ R    EEE+  R++E  ++++EEK++E+E +   + ++ +EQ  K+ 
Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282

Query: 58  EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE 117
            QE +   QEE+  +Q+   EQ+ +  +++ER  ++EER  +Q+  +Q E+ RE++  +E
Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342

Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQ---EEKMREQEEKMREQE---EKMQG 171
           ++ + +++  +EQEE   EQ+ + +++EE+  +Q   E+++R +++  REQ+   E+   
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402

Query: 172 QEEKMR 177
           +E+++R
Sbjct: 403 REQQLR 408



 Score =  100 bits (249), Expect = 1e-21
 Identities = 53/200 (26%), Positives = 130/200 (65%), Gaps = 25/200 (12%)

Query: 2    REEERMREREKKMREEEEMMREQ---------EEKMQEQEEKMREQEEKMW--EQEEKMQ 50
            R +E+ R+++ + + EEE  R +         +E+++++++ ++E+EE++   E+E++ +
Sbjct: 864  RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR 923

Query: 51   EQEEKMWEQEEKMWEQEEKMWEQQ---RLPEQKEKMWEQDERLREKEERMREQKMWQQVE 107
            +++E+ + +EE++ ++EE++  ++   R  +++E+ + +D++L++KEE++  ++  ++  
Sbjct: 924  QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983

Query: 108  KMREKKKTQEEKMQEQEEKM----------QEQEEMMWEQEEKMQEQEEKMWEQEEKMRE 157
            + REKK  +EE++Q++EE++          QE E    +++E  QE+E+ + E+ EK R 
Sbjct: 984  QEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRL 1043

Query: 158  QE-EKMREQEEKMQGQEEKM 176
            QE E+   +EE++Q +EE++
Sbjct: 1044 QERERQYREEEELQQEEEQL 1063



 Score =  100 bits (249), Expect = 1e-21
 Identities = 59/183 (32%), Positives = 116/183 (63%), Gaps = 19/183 (10%)

Query: 3    EEERMREREKKMREEEEMMREQEE---KMQEQEEKMREQEEKMWEQEE---KMQEQEEKM 56
            E++  + R++K +EE++++RE+ E   + QE + K RE+E+ + E+EE   + QE++ K 
Sbjct: 1303 EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362

Query: 57   WEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116
             E+E +  EQ  K  E+    EQ+ +  E++ +  ++E+++R Q+  QQ+ + R++K  +
Sbjct: 1363 REEELRHQEQGRKFLEE----EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE 1418

Query: 117  EEKM---QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-EQEEKMREQEEKMQGQ 172
            EE+    QE++ K +E+     EQ+ + QE+E K  E+E+++R E+  K RE+E+ +Q +
Sbjct: 1419 EEQQLSRQERDRKFREE-----EQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473

Query: 173  EEK 175
            EE+
Sbjct: 1474 EEQ 1476



 Score = 99.8 bits (247), Expect = 2e-21
 Identities = 57/201 (28%), Positives = 118/201 (58%), Gaps = 23/201 (11%)

Query: 3    EEERMREREKKMREEEEMMREQEEKMQEQE--EKMREQEEKMWEQEEKMQEQEEKM---- 56
            EE+  R R+++ RE+E    E+EE++Q +E  ++++E+E+ + E +E+ + QE++     
Sbjct: 815  EEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKW 874

Query: 57   -WEQEEKMWEQEEKMWEQQRLPEQKEK-----MWEQDERLREKEERMREQKMWQQVEKMR 110
             W+ EE+   +   ++ +  L EQ  K       E++E  RE+ E+ R Q+  +Q  +  
Sbjct: 875  RWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEE 934

Query: 111  EKKKTQEEKMQEQEEKMQEQE-EMMWEQEEKMQEQEEKMW----------EQEEKMREQE 159
            + ++ +E+ ++E+ EK + QE E  + +++K+Q++EE++           E+E+K RE+E
Sbjct: 935  QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE 994

Query: 160  EKMREQEEKMQGQEEKMRDVE 180
            E  +E+E+ ++ + EK R  E
Sbjct: 995  ELQQEEEQLLREEREKRRRQE 1015



 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 60/175 (34%), Positives = 110/175 (62%), Gaps = 13/175 (7%)

Query: 3   EEERMREREKKMREEE--EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ---EEKMW 57
           +EE  RER  K+ EEE  E    +E++++ ++E+ REQ  K  E+EE++Q++   E+++ 
Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539

Query: 58  EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE 117
            ++E+  EQ  K  E++RL +++     +++RL+ ++E  R+Q + ++ E+ +++ K ++
Sbjct: 540 REQEERREQLLKREEEKRLEQER-----REQRLKREQEERRDQLLKREEERRQQRLKREQ 594

Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 172
           E+  EQ  K +E E +  EQEE+ +EQ  K  E EE+ R+Q  K  EQEE+ Q Q
Sbjct: 595 EERLEQRLKREEVERL--EQEER-REQRLKREEPEEERRQQLLKSEEQEERRQQQ 646



 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 71/189 (37%), Positives = 110/189 (58%), Gaps = 15/189 (7%)

Query: 2   REEERMREREKKMREE--EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
           REEER ++R K+ +EE  E+ ++ +E +  EQEE+ REQ  K  E EE+ ++Q  K  EQ
Sbjct: 581 REEERRQQRLKREQEERLEQRLKREEVERLEQEER-REQRLKREEPEEERRQQLLKSEEQ 639

Query: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERL-----REKEERMREQKMWQQV-EKMREKK 113
           EE+  +Q  +  EQQ   EQ+ K  E++ERL     RE EE  REQ++ ++  E+ RE+ 
Sbjct: 640 EERRQQQLRR--EQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERI 697

Query: 114 KTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE----KM 169
           K++  K Q Q E   +  +       + QE + +  EQEEK R +E +++ QEE    + 
Sbjct: 698 KSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQ 757

Query: 170 QGQEEKMRD 178
           Q +EE+ RD
Sbjct: 758 QQEEEQRRD 766



 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 61/205 (29%), Positives = 115/205 (56%), Gaps = 27/205 (13%)

Query: 3    EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE-EKMWEQEEKMQEQEEKMWEQE- 60
            E+ R +ERE++ REEEE+ +E+E+ ++E+ EK R QE E+ + +EE++Q++EE++  +E 
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158

Query: 61   --------EKMWEQEEKMW--EQQRLPEQKEKMWEQDERLREKEERMREQKMWQQV--EK 108
                    E+ + +EE++   E+Q L E++EK  ++ ER   +EE ++ QK  Q+   E 
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218

Query: 109  MREKKKTQEEKMQE-------------QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM 155
             R   K Q E  +E             + E+ ++ E+      +  Q+ +  + EQ+E+ 
Sbjct: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD 1278

Query: 156  REQEEKMREQEEKMQGQEEKMRDVE 180
            REQE +  +Q ++   +EE++   E
Sbjct: 1279 REQERRRWQQRDRHFPEEEQLEREE 1303



 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 58/196 (29%), Positives = 121/196 (61%), Gaps = 23/196 (11%)

Query: 3    EEERMR--EREKKMREEEEMMREQEEK---MQEQEEKMREQEEKMWEQEEKMQEQEEKMW 57
            EE+++R  ER++K REEE+ +R QE +   +QE+++  R++ E+ + +EE+++++ E+  
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ-- 1737

Query: 58   EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLRE--KEERMREQKMWQQVE------KM 109
            EQ  +     + + E+Q  PE++E+   + ER R+  +EE++R+++  QQ+       K 
Sbjct: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKF 1797

Query: 110  REKKKTQEEKMQEQEEKMQEQEEMMWEQEE-KMQEQEEKM-------WEQEEKMREQEEK 161
            RE+++ ++E+ ++Q    Q   +  WE+E+ +++EQE+++       +  EE+   QE+ 
Sbjct: 1798 REEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKS 1857

Query: 162  MREQEEKMQGQEEKMR 177
             RE++E  Q +E+K R
Sbjct: 1858 RREEQELWQEEEQKRR 1873



 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 63/189 (33%), Positives = 116/189 (61%), Gaps = 24/189 (12%)

Query: 1   MREEERMRE---REKKMREEEEMMREQEEKMQEQEE----KMREQEEKMWEQEEKMQEQE 53
           + EEER  +   RE+++R E+E  REQ  K QE+EE    ++R +++   EQEE+   +E
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER---RE 547

Query: 54  EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113
           + +  +EEK  EQE +   +QRL  ++E+   +D+ L+ +EER +++   +Q E++ ++ 
Sbjct: 548 QLLKREEEKRLEQERR---EQRLKREQEE--RRDQLLKREEERRQQRLKREQEERLEQRL 602

Query: 114 KTQEEKMQEQEE------KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167
           K +E +  EQEE      K +E EE   +Q  K +EQEE+   +++++R ++++ REQ  
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER---RQQQLRREQQERREQRL 659

Query: 168 KMQGQEEKM 176
           K + +EE++
Sbjct: 660 KREEEEERL 668



 Score = 97.4 bits (241), Expect = 9e-21
 Identities = 63/216 (29%), Positives = 128/216 (59%), Gaps = 37/216 (17%)

Query: 2    REEERM--REREKKMREEEEMMREQEE--KMQEQEEKMREQEEKMWEQEEKM--QEQEEK 55
            REE+++  +ER++K  EEE+ +R QE   K +EQE + +E E K  E+E+++  Q+++ K
Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRK 1532

Query: 56   MWEQEEKMWEQEE----------KMWEQQRLPEQKEKMW----EQDERLREKEERMREQK 101
              ++E+++  QE           K  E+++L +++E+      E+D + R +E+++R Q+
Sbjct: 1533 FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQE 1592

Query: 102  M---WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKM---QEQEEKMWEQEEKM 155
                + + E+   +++ Q++  QE++ K +E E+++ E+EE+    QE++ K  E+E ++
Sbjct: 1593 QERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQL 1652

Query: 156  REQE----------EKMREQEEKMQ-GQEEKMRDVE 180
            R QE           K RE+E+ +Q G+E+++R  E
Sbjct: 1653 RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQE 1688



 Score = 97.4 bits (241), Expect = 9e-21
 Identities = 57/203 (28%), Positives = 120/203 (59%), Gaps = 18/203 (8%)

Query: 1    MREEERMR--EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 58
            ++EE+++R  E E+K REEE++ +E E++   ++E+ R    K+ E+E+   E+EE+   
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR----KILEEEQLRPEREEQQLR 1765

Query: 59   QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
            ++E+  +  E+   +Q   EQ+ +  E D + RE+E+  +E++  Q   + R+ K   EE
Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE 1825

Query: 119  ---KMQEQEEKMQEQEEMMWEQE------EKMQEQEEKMWEQEEKMREQEEKMREQEE-- 167
               +++EQE++++++ +  +  E      EK + +E+++W++EE+ R QE + + +EE  
Sbjct: 1826 EQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHI 1885

Query: 168  -KMQGQEEKMRDVEPAGGEAGEG 189
             + Q +E++ R V     + G+G
Sbjct: 1886 RRQQKEEQRHRQVGEIKSQEGKG 1908



 Score = 97.1 bits (240), Expect = 1e-20
 Identities = 62/186 (33%), Positives = 119/186 (63%), Gaps = 13/186 (6%)

Query: 2   REEERMREREKKMREEEEMMREQEEK---MQEQEEKMREQEEKMWEQEEKMQEQEEK-MW 57
           +EEER  ++ ++ R E+ + REQEE+   ++ +EE  R ++E+  +Q ++ QE+E +  W
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488

Query: 58  ---EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKK 114
              E+EE+  +QE +  EQQ   EQ+E+  EQ  + +E+EER+ +Q++  + +  RE+++
Sbjct: 489 LKLEEEERREQQERR--EQQLRREQEERR-EQRLKRQEEEERL-QQRLRSEQQLRREQEE 544

Query: 115 TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 174
            +E+ ++ +EEK  EQE      + + +E+ +++ ++EE+ R+Q  K REQEE+++ Q  
Sbjct: 545 RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK-REQEERLE-QRL 602

Query: 175 KMRDVE 180
           K  +VE
Sbjct: 603 KREEVE 608



 Score = 96.7 bits (239), Expect = 2e-20
 Identities = 56/190 (29%), Positives = 119/190 (62%), Gaps = 17/190 (8%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQ-----EQEEK-----MREQEEKMWEQEEKMQE 51
           ++EE  RE++++ RE++E   +QEE+ +     EQEE+      REQEE+  EQ+ + ++
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368

Query: 52  QEEKMWEQ---EEKMWEQEEKMWEQQRLPEQ---KEKMWEQDERLREKEERMREQKMWQQ 105
           +EE+  +Q   E+++  +++   EQQ   EQ   +E+   ++++LR +++  REQ++ ++
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428

Query: 106 VEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 165
            E+ R ++K ++E+ +EQ  K +++E   W + E+  E+ E+   +++  R+QEE+ RE+
Sbjct: 429 QEEERHEQKHEQER-REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487

Query: 166 EEKMQGQEEK 175
             K++ +E +
Sbjct: 488 WLKLEEEERR 497



 Score = 96.3 bits (238), Expect = 2e-20
 Identities = 59/186 (31%), Positives = 122/186 (65%), Gaps = 22/186 (11%)

Query: 2    REEERM--REREKKMREEEEMMREQEEKMQ---EQEEKMREQEEKMWEQEEKM---QEQE 53
            REE+++  +ER++K  EEE  +R QE + Q   +++ K RE+E+ + E EE+    QE++
Sbjct: 1631 REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690

Query: 54   EKMWEQEEKMWEQEEK---MWEQQRLPEQK-EKMWEQDERLREK--EERMREQKMWQQV- 106
             K  E+E+++  QE +   + E+Q+L  Q+ E+ + ++E+LR++  +E++R Q+ ++++ 
Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKIL 1750

Query: 107  --EKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164
              E++R +++ Q+ + QE++ K +E+E++  E+EE    Q+ +  E + K RE EE++R+
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE----QQLRSQESDRKFRE-EEQLRQ 1805

Query: 165  QEEKMQ 170
            + E+ Q
Sbjct: 1806 EREEQQ 1811



 Score = 95.9 bits (237), Expect = 3e-20
 Identities = 55/184 (29%), Positives = 114/184 (61%), Gaps = 8/184 (4%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R E+++R  +++ R E+++ REQEE+ +EQ+ +  +Q  +  +   + Q + E+   +E+
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREK-EERMREQKMWQQVEKMREKKKTQEE-K 119
           ++  +++   EQQ   EQ+ +  +++ER  +K E+  REQ++ ++ E+ R+  K +EE +
Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465

Query: 120 MQEQEEKMQ----EQEEMMWEQEEKMQEQE--EKMWEQEEKMREQEEKMREQEEKMQGQE 173
             EQE + Q    +QEE   E+  K++E+E  E+   +E+++R ++E+ REQ  K Q +E
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 525

Query: 174 EKMR 177
           E+++
Sbjct: 526 ERLQ 529



 Score = 95.9 bits (237), Expect = 3e-20
 Identities = 66/240 (27%), Positives = 132/240 (55%), Gaps = 28/240 (11%)

Query: 1    MREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE----------QEEKMWEQEEKMQ 50
            ++EEE   + +++ R  +E  R+Q+ + Q +EE+ R           QE+   EQ+   +
Sbjct: 849  LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908

Query: 51   EQEEKMWEQEEK--MWEQEEKMWEQQRLPEQKEKMWEQD---ERLREKEERMREQKMWQQ 105
            E+EE   E+ EK    EQE +  E+++L +++E++  ++    R +E+E + R+ K  QQ
Sbjct: 909  EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968

Query: 106  VEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKM----WE-----QEEKMR 156
             E+    ++ ++ + QE+E+K +E+EE+  E+E+ ++E+ EK     WE     ++E  +
Sbjct: 969  KEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ 1028

Query: 157  EQEEKMREQEEK--MQGQEEKMRDVEPAGGEAGE--GSPQDNPTAQEIMQLFCGMKNAQQ 212
            E+E+ +RE+ EK  +Q +E + R+ E    E  +  G  ++    QE+ + +   +  QQ
Sbjct: 1029 EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ 1088



 Score = 95.5 bits (236), Expect = 4e-20
 Identities = 60/185 (32%), Positives = 112/185 (60%), Gaps = 13/185 (7%)

Query: 2   REEERMREREKKMREEEEMMREQ---EEKMQEQEEKMREQ-----EEKMWEQEEKMQEQE 53
           RE+E  RE+  K +EEEE ++++   E++++ ++E+ REQ     EEK  EQE + Q  +
Sbjct: 509 REQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK 568

Query: 54  EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQV--EKMRE 111
            +  E+ +++ ++EE+   QQRL  ++E+  EQ  +  E E   +E++  Q++  E+  E
Sbjct: 569 REQEERRDQLLKREEER-RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEE 627

Query: 112 KKKTQEEKMQEQEEKMQEQ--EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 169
           +++ Q  K +EQEE+ Q+Q   E    +E++++ +EE+   ++   RE EE+ REQE   
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687

Query: 170 QGQEE 174
           + QE+
Sbjct: 688 EEQEQ 692



 Score = 95.5 bits (236), Expect = 4e-20
 Identities = 55/184 (29%), Positives = 112/184 (60%), Gaps = 12/184 (6%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQ--EQEEKMREQEEKMWEQEEKMQEQE-EKMWE 58
            +EEE  +E E+ +REE E  R QE + Q  E+EE  +E+E+ + E+ EK + QE E+ + 
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141

Query: 59   QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEE 118
            +EE++ ++EE++  ++  PE++ +  E + + RE+EE  +E++  Q + + +EK++ + E
Sbjct: 1142 EEEEVQQEEEQLLREE--PEKRRRQ-ELERQYREEEELQQEEE--QLLREEQEKRRQERE 1196

Query: 119  KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM----REQEEKMQGQEE 174
            +   +EE++Q Q+     ++E  +   +  WE E++   ++ K+    RE E+  Q ++ 
Sbjct: 1197 RQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDS 1256

Query: 175  KMRD 178
            ++RD
Sbjct: 1257 QLRD 1260



 Score = 95.5 bits (236), Expect = 4e-20
 Identities = 63/213 (29%), Positives = 129/213 (60%), Gaps = 38/213 (17%)

Query: 3    EEERMRERE----------KKMREEEEMMREQEEKMQ---EQEEKMREQEEKMWEQEE-- 47
            +E+ ++ERE          +K  EEE  +R QE + Q   +++ K RE+E+ + E EE  
Sbjct: 1624 DEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ 1683

Query: 48   -KMQEQEEKMWEQEEKMWEQEEK---MWEQQRLPEQK-EKMWEQDERLRE--KEERMREQ 100
             + QE++ K  E+E+++  QE +   + E+Q+L  Q+ E+ + ++E+LR+  ++E++R Q
Sbjct: 1684 LRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQ 1743

Query: 101  KMWQQV---EKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE---KMQEQEEKMWEQEEK 154
            + ++++   E++R +++ Q+ + QE++ K +E+E++  E+EE   + QE + K  E+E+ 
Sbjct: 1744 ERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQL 1803

Query: 155  MREQEE----------KMREQEEKMQGQEEKMR 177
             +E+EE          K R +EE++Q +E++ R
Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836



 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 54/185 (29%), Positives = 109/185 (58%), Gaps = 15/185 (8%)

Query: 3   EEERMRER---EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
           + ER R+R      +RE+ E     EE+ Q ++  + E+EEK   + ++ + ++E  + +
Sbjct: 776 KSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLE 835

Query: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT---- 115
           EE+  ++ E+    Q+L E+++ + E  ER R +E+R  ++  WQ  E+ + ++ T    
Sbjct: 836 EEEQLQRRERA---QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK 892

Query: 116 ---QEEKMQEQEEKMQEQEEMMWEQEEKMQEQE-EKMWEQEEKMREQEEK-MREQEEKMQ 170
              QE+  +EQ+   +E+EE+  E+ EK + QE E+ + +EE+++++EE+ +RE+ EK +
Sbjct: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 952

Query: 171 GQEEK 175
            QE +
Sbjct: 953 RQERE 957



 Score = 94.4 bits (233), Expect = 8e-20
 Identities = 61/201 (30%), Positives = 124/201 (61%), Gaps = 24/201 (11%)

Query: 1   MREEERMREREKKMREEEEMMREQ----EEKMQEQEEKMREQE---EKMWEQEEKMQEQE 53
           +R E+    RE+++R E+++ REQ    E++++ +++  REQ+   E+   +E++++ ++
Sbjct: 364 LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 423

Query: 54  EKMWEQEEKMWEQ--EEKMWEQQRLPEQKEK---MWEQDERLREKEERMREQKMWQQVEK 108
           +   EQEE+  EQ  E++  EQ+   EQ+E+   +  ++E  R ++ER ++Q    Q E+
Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEE 483

Query: 109 MREK-KKTQEEKMQEQEEKMQEQ----EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 163
            RE+  K +EE+ +EQ+E+ ++Q    +E   EQ  K QE+EE++   ++++R +++  R
Sbjct: 484 RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL---QQRLRSEQQLRR 540

Query: 164 EQEEK----MQGQEEKMRDVE 180
           EQEE+    ++ +EEK  + E
Sbjct: 541 EQEERREQLLKREEEKRLEQE 561



 Score = 94.4 bits (233), Expect = 8e-20
 Identities = 58/199 (29%), Positives = 118/199 (59%), Gaps = 17/199 (8%)

Query: 1    MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM---QEQEEKMW 57
            + EE+R+R +E   RE + +  EQ+ + QE+E+++R+  ++ + +EE+    QE++ K  
Sbjct: 1377 LEEEQRLRRQE---RERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFR 1433

Query: 58   EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE 117
            E+E+++  QE    E++ L E+++   E+  + RE+E+ ++E++  Q   + R++K  +E
Sbjct: 1434 EEEQQVRRQER---ERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE 1490

Query: 118  E---KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQ--EEKMREQEEKMREQE---EKM 169
            E   + QE++ K +EQE    E E K  E+E+++  Q  + K  ++E+++R QE   ++ 
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRR 1550

Query: 170  QGQEEKMRDVEPAGGEAGE 188
            Q ++ K R+ E    E  E
Sbjct: 1551 QDRDRKFREEEQLRQEREE 1569



 Score = 94.4 bits (233), Expect = 8e-20
 Identities = 59/213 (27%), Positives = 129/213 (60%), Gaps = 34/213 (15%)

Query: 1    MREEERM--REREKKMREEEEMMREQE---EKMQEQEEKMREQEEKMWEQEE-------- 47
            + EE+++  ++R++K  +EE+ +R QE   ++ Q+++ K RE+E+   E+EE        
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577

Query: 48   ----KMQEQEEKMWEQEEKMWEQEEKMWE---QQRLPEQKEKMWEQDER-LREKEERM-- 97
                +++EQ+ +  EQE K  E E+++     QQ+L +++++ + +DE+ L+E+EE+   
Sbjct: 1578 DRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLH 1637

Query: 98   ---REQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE---KMQEQEEKMWEQ 151
               R++K  ++  ++R +++ Q+ +  +++ K +E+E+++ E EE   + QE++ K  E+
Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLR-HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREE 1696

Query: 152  EEKMREQEEKMR----EQEEKMQGQEEKMRDVE 180
            E+++R QE + +    EQ+ + Q  E K R+ E
Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEE 1729



 Score = 94.0 bits (232), Expect = 1e-19
 Identities = 59/186 (31%), Positives = 107/186 (57%), Gaps = 14/186 (7%)

Query: 2   REEERMREREKKMREE---EEMMREQEEKMQE---QEEKMREQEEKMWEQEEKMQEQEEK 55
           RE+E  R++  K  EE   + + REQEE++++   +EE  R ++E+  EQ  K +E EE+
Sbjct: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628

Query: 56  MWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT 115
             +Q  K  EQEE+   QQ+L  ++++  EQ  +  E+EER+ ++   +  E+ RE++  
Sbjct: 629 RRQQLLKSEEQEER--RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELA 686

Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMW------EQEEKMREQEEKMREQEEKM 169
           +EE+ Q +E       +  W+ E +   ++ K++      E + + +EQEEK R +E ++
Sbjct: 687 EEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL 746

Query: 170 QGQEEK 175
           Q QEE+
Sbjct: 747 QWQEEE 752



 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 59/218 (27%), Positives = 116/218 (53%), Gaps = 49/218 (22%)

Query: 3    EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK-------MWEQEEKMQEQEEK 55
            EE+ +RE ++K R+E E    +EE++Q Q+ K R ++E         WE E++   ++ K
Sbjct: 1180 EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239

Query: 56   MW-------------------------------EQEEKMWEQEEKMWEQ--QRLPEQKEK 82
            ++                               EQ+E+  EQE + W+Q  +  PE+   
Sbjct: 1240 VYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEE--- 1296

Query: 83   MWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE--- 139
              EQ ER  +KE + R++K  ++ + +RE+++ ++ + QE + K +E+E+++ E+EE   
Sbjct: 1297 --EQLEREEQKEAKRRDRKSQEEKQLLREERE-EKRRRQETDRKFREEEQLLQEREEQPL 1353

Query: 140  KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
            + QE++ K  E+E + +EQ  K  E+E++++ QE + +
Sbjct: 1354 RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERK 1391



 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 53/197 (26%), Positives = 113/197 (57%), Gaps = 26/197 (13%)

Query: 3   EEERMREREKKMREEEEMMREQEEKM--QEQEEKMREQEEKMWEQEEKMQEQEEK----- 55
           +  R  + EK+ R E E+  ++EE+   Q+QEE+ R      W+ EEK +   ++     
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788

Query: 56  -MWEQEEKMWEQEEKMWEQQR-LPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113
            + EQ E+    EE+   +QR LPE++EK    ++R R++ ER +E +  ++ E+++ ++
Sbjct: 789 PLREQRERQLRAEERQQREQRFLPEEEEK----EQRRRQRREREKELQFLEEEEQLQRRE 844

Query: 114 KTQ-----EEKMQEQEEKMQEQEE-----MMWEQEEKMQEQEEKMWEQ---EEKMREQEE 160
           + Q     E+ +QE +E+ + QE+       W+ EE+ + +   ++ +   +E++R++++
Sbjct: 845 RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQ 904

Query: 161 KMREQEEKMQGQEEKMR 177
            ++E+EE++Q +E + R
Sbjct: 905 LLQEEEEELQREEREKR 921



 Score = 92.8 bits (229), Expect = 2e-19
 Identities = 54/194 (27%), Positives = 115/194 (59%), Gaps = 17/194 (8%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ-------EEKMQEQEE 54
            RE E+ R+ E     + +  ++ +  + EQ+E+ REQE + W+Q       EE+++ +E+
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304

Query: 55   KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKK 114
            K  ++ ++  ++E+++  ++R  E+K +  E D + RE+E+ ++E++      + R++K 
Sbjct: 1305 KEAKRRDRKSQEEKQLLREER--EEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362

Query: 115  TQEE-KMQEQEEKMQEQEEMMWEQEEK----MQEQEEKMWEQEEKMR-EQEEKMREQEEK 168
             +EE + QEQ  K  E+E+ +  QE +     +EQ+ +  E+E+++R +++ K RE+E++
Sbjct: 1363 REEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ 1422

Query: 169  MQGQE--EKMRDVE 180
            +  QE   K R+ E
Sbjct: 1423 LSRQERDRKFREEE 1436



 Score = 92.4 bits (228), Expect = 3e-19
 Identities = 58/193 (30%), Positives = 118/193 (61%), Gaps = 14/193 (7%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQE----QEEKMREQEEKMWEQEEKMQEQEEKMW 57
           R E+++R  +++ RE+    +E+EE++Q+    +++  REQEE+   +E+ ++ +EEK  
Sbjct: 502 RREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER---REQLLKREEEKRL 558

Query: 58  EQEEKMWEQEEKMWEQQRLPE--QKEKMWEQDERLREKEERMREQKMWQQVEKM-REKKK 114
           EQE +  EQ  K  +++R  +  ++E+   Q    RE+EER+ ++   ++VE++ +E+++
Sbjct: 559 EQERR--EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616

Query: 115 TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ--EEKMWEQEEKMREQEEKMREQEEKMQGQ 172
            Q  K +E EE+ ++Q     EQEE+ Q+Q   E+   +E++++ +EE+ R ++   +  
Sbjct: 617 EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREH 676

Query: 173 EEKMRDVEPAGGE 185
           EE+ R+ E A  E
Sbjct: 677 EEERREQELAEEE 689



 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 48/189 (25%), Positives = 123/189 (65%), Gaps = 14/189 (7%)

Query: 1    MREEERMR--EREKKMREEEEM-MREQEEKM--QEQEEKMREQEEKM--WEQEEKMQEQE 53
            ++EE+++R  ERE+++R++ +   RE+E+++  QE++ K RE+E+++   E+E K  E+E
Sbjct: 1393 LKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452

Query: 54   EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113
            +++ ++  + + +EE++ +++   EQ+    E+D +  E+E+++R Q+  ++  +   + 
Sbjct: 1453 QQLRQERHRKFREEEQLLQERE--EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510

Query: 114  KTQEEKMQEQEEKM--QEQEEMMWEQEEKMQEQE---EKMWEQEEKMREQEEKMREQEEK 168
            +  E K  E+E+++  Q+++    ++E++++ QE   ++  +++ K RE+E+  +E+EE+
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQ 1570

Query: 169  MQGQEEKMR 177
               ++E+ R
Sbjct: 1571 QLSRQERDR 1579



 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 62/205 (30%), Positives = 121/205 (59%), Gaps = 22/205 (10%)

Query: 3    EEERMR--EREKKMREEEEMMREQEEKMQ---EQEEKMREQEEKMWEQEEK-M--QEQEE 54
            EE+++R  E+E+K  E+E+ +R QE + Q   E++ K RE E+ + E+EE+ +  QE++ 
Sbjct: 1584 EEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDR 1643

Query: 55   KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERM-----REQKMWQQVEKM 109
            K  E+E ++  QE    EQQ   ++  K  E+++ L+E EE+      R++K  ++ +++
Sbjct: 1644 KFLEEEPQLRRQER---EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700

Query: 110  REKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE--QEEKMR---- 163
            R +++ ++   +EQ+ + QE E    E+E+  QE E++   ++E+ R+  +EE++R    
Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760

Query: 164  EQEEKMQGQEEKMRDVEPAGGEAGE 188
            EQ+ + Q ++ K R+ E    E  E
Sbjct: 1761 EQQLRRQERDRKFREEEQLRQEREE 1785



 Score = 89.4 bits (220), Expect = 3e-18
 Identities = 71/224 (31%), Positives = 116/224 (51%), Gaps = 48/224 (21%)

Query: 3   EEERMREREKKMREEEEMM-----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQ--EEK 55
           +EER+ +R K  REE E +     REQ  K +E EE+ R+Q  K  EQEE+ Q+Q   E+
Sbjct: 594 QEERLEQRLK--REEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ 651

Query: 56  MWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ-----KMWQ-QVEK- 108
              +E+++  +EE+   +QRL  + E+   + E   E++E+ RE+       WQ Q+E  
Sbjct: 652 QERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESE 711

Query: 109 ---------MREKKKTQEEKMQEQEEKMQEQE-EMMWEQEEK--MQEQEEK-------MW 149
                     R +K+  + + QEQEEK + +E E+ W++EE+   Q+QEE+        W
Sbjct: 712 ADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQW 771

Query: 150 EQEEK-------------MREQEEKMREQEEKMQGQEEKMRDVE 180
           + EEK             +REQ E+    EE+ Q ++  + + E
Sbjct: 772 QAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEE 815



 Score = 89.0 bits (219), Expect = 3e-18
 Identities = 66/234 (28%), Positives = 118/234 (50%), Gaps = 54/234 (23%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKM-----REQEEKMWEQEEKMQEQEEK 55
           ++ EE+   R++++R E++  REQ  K +E+EE++     RE EE+  EQE   +EQE+ 
Sbjct: 634 LKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA 693

Query: 56  -----------MWEQEE-------KMWEQEEKMWEQQRLPEQKEK--------MWEQDER 89
                       W+ E        K++ +  K   Q+R  EQ+EK         W+++ER
Sbjct: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEER 753

Query: 90  L--REKEERMREQKMWQ-QVEKMREKKKT----------QEEKMQEQEEKMQEQEEMMWE 136
              +++EE  R    WQ Q E+  E+ +           Q E+    EE+ Q ++  + E
Sbjct: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE 813

Query: 137 QEEKMQ--------EQEEKMWEQEEKM--REQEEKMREQEEKMQGQEEKMRDVE 180
           +EEK Q        E+E +  E+EE++  RE+ ++++E+E+ +Q  +E+ R  E
Sbjct: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867



 Score = 89.0 bits (219), Expect = 3e-18
 Identities = 51/182 (28%), Positives = 116/182 (63%), Gaps = 8/182 (4%)

Query: 3    EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM--QEQEEKMWEQE 60
            ++ER RE+E++  ++ +    +EE+++ +E+K  ++ ++  ++E+++  +E+EEK   QE
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333

Query: 61   EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEE 118
                 +EE+   Q+R  EQ  +  E+D + RE+E R +EQ  K  ++ +++R +++ ++ 
Sbjct: 1334 TDRKFREEEQLLQER-EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKF 1392

Query: 119  KMQEQEEKMQEQEEMM-WEQEEKMQEQEEKMWEQE--EKMREQEEKMREQEEKMQGQEEK 175
              +EQ+ + QE+E+ +  +++ K +E+E+++  QE   K RE+E+++R QE + +  EE+
Sbjct: 1393 LKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452

Query: 176  MR 177
             +
Sbjct: 1453 QQ 1454



 Score = 88.6 bits (218), Expect = 4e-18
 Identities = 56/184 (30%), Positives = 104/184 (56%), Gaps = 20/184 (10%)

Query: 2   REEERMREREKKMRE-EEEMMREQEEKMQEQEEKMREQEEKMWEQEE----KMQEQEEKM 56
           R+EE  R  E + R+ EEE  + + +K QEQE ++ E EE+  +QE       Q ++E++
Sbjct: 114 RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL 173

Query: 57  WEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116
           W Q ++  E+EE+  E+++L   K    E+       EE++R +++ +   K RE+K  Q
Sbjct: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEFP----DEEQLRRRELLELRRKGREEK--Q 227

Query: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
           +++ + Q+   QE+EE  W + E +  +EE+  ++EE  R++E         +Q +EE++
Sbjct: 228 QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE---------LQEEEEQL 278

Query: 177 RDVE 180
           R +E
Sbjct: 279 RKLE 282



 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 48/160 (30%), Positives = 98/160 (61%), Gaps = 5/160 (3%)

Query: 22  REQEEKMQEQEEKMREQEEKM-WEQEEKM--QEQEEKMWEQEEKMWEQEEKMWE-QQRLP 77
           +E + + QEQEEK R +E ++ W++EE+   Q+QEE+        W+ EEK    +QRL 
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785

Query: 78  EQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQ 137
            +     +++ +LR +E + REQ+   + E+  ++++ + E+ +E +   +E++    E+
Sbjct: 786 ARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRER 845

Query: 138 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
            +++QE+E+ + E +E+ R QE++ R+Q+ + Q +EE+ R
Sbjct: 846 AQQLQEEEDGLQEDQERRRSQEQR-RDQKWRWQLEEERKR 884



 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 53/203 (26%), Positives = 123/203 (60%), Gaps = 11/203 (5%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
           +R E+++R RE++ R E+ + RE+E++++++  + R + E+   +++ ++ +EE+   Q+
Sbjct: 532 LRSEQQLR-REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER--RQQ 588

Query: 61  EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMR-EQKMWQQVEKMREKKKTQEEK 119
               EQEE++  +QRL  ++ +  EQ+ER  ++ +R   E++  QQ+ K  E+++ ++++
Sbjct: 589 RLKREQEERL--EQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646

Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE---EKMQGQEEKM 176
           ++ ++++ +EQ     E+EE+++++ ++  E EE+ REQE    EQE   E+++ +  K 
Sbjct: 647 LRREQQERREQRLKREEEEERLEQRLKR--EHEEERREQELAEEEQEQARERIKSRIPKW 704

Query: 177 RDVEPAGGEAGEGSPQDNPTAQE 199
           +    +  +A +      P  QE
Sbjct: 705 QWQLESEADARQSKVYSRPRKQE 727



 Score = 71.6 bits (174), Expect = 6e-13
 Identities = 44/169 (26%), Positives = 97/169 (57%), Gaps = 19/169 (11%)

Query: 32  EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE------EKMWEQQRLPEQKEKMWE 85
           EEK    + K    +++ QE++++ +E  ++  E+E      +K  EQ+R   + E+  E
Sbjct: 97  EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156

Query: 86  QDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQE 145
           + ERL +++ + R++++W+Q ++ +E+++ + E+ Q Q  K  E EE   E++ + +E  
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216

Query: 146 E---KMWEQEEKMR----------EQEEKMREQEEKMQGQEEKMRDVEP 181
           E   K  E++++ R          E+E++ R++E  ++ +EEK+++ EP
Sbjct: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 27/116 (23%), Positives = 64/116 (55%), Gaps = 7/116 (6%)

Query: 3    EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
            E+ ++ E+E+++R+E +     EE+   QE+  RE++E +W++EE+ + QE +   +EE 
Sbjct: 1826 EQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE-LWQEEEQKRRQERERKLREEH 1884

Query: 63   MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEER------MREQKMWQQVEKMREK 112
            +  Q+++    +++ E K +  +   RL E          +R   +++ +++ R +
Sbjct: 1885 IRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQ 1940



 Score = 35.0 bits (79), Expect = 0.057
 Identities = 25/109 (22%), Positives = 52/109 (47%), Gaps = 6/109 (5%)

Query: 111 EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 170
           EK+   + K    +++ QE+++  +E  ++ Q +EE    + +K +EQE ++ E EE+ +
Sbjct: 98  EKRARCDGKESLLQDRRQEEDQRRFEPRDR-QLEEEPGQRRRQKRQEQERELAEGEEQSE 156

Query: 171 GQE-----EKMRDVEPAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQCP 214
            QE     ++ R  E    +  E   ++   A+E     C     ++ P
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFP 205


>gi|169208458 PREDICTED: similar to golgi autoantigen, golgin
           subfamily a-like [Homo sapiens]
          Length = 432

 Score =  113 bits (282), Expect = 2e-25
 Identities = 67/190 (35%), Positives = 117/190 (61%), Gaps = 9/190 (4%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+EER+RE+E+++RE+EE + EQEE++ EQEE++REQEE++ EQE+     +E++ E+ E
Sbjct: 196 RQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEK--LPGQERLLEEVE 253

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121
           K+ +QE +  EQ+RL E++  + E +E L ++  R +++++WQQ E +RE      E+++
Sbjct: 254 KLLKQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQ-ETLREL-----ERLR 307

Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEP 181
           E E  ++   E ++EQ  + +   E++   E K   Q E+  ++ EK  G EE       
Sbjct: 308 ELERMLELGWEALYEQRAEPRSGFEEL-NNENKSTLQLEQQVKELEKSGGAEEPRGSESA 366

Query: 182 AGGEAGEGSP 191
           A      G+P
Sbjct: 367 AAARPVPGAP 376



 Score =  108 bits (270), Expect = 4e-24
 Identities = 66/203 (32%), Positives = 124/203 (61%), Gaps = 29/203 (14%)

Query: 5   ERMREREKKMREEEEMMREQEEKMQE-----------QEEKMREQEEKMWEQEEKMQEQE 53
           E++++    +R+E E +  Q +   E           QEE++REQEE++ EQEE++ EQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQE 219

Query: 54  EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113
           E++ EQEE++ EQEE++ EQ++LP Q E++ E+ E+L ++E R  EQ+   +    RE+ 
Sbjct: 220 ERLCEQEERLREQEERLCEQEKLPGQ-ERLLEEVEKLLKQERRQEEQERLLE----RERL 274

Query: 114 KTQEEKMQEQEEKMQEQEEMMWEQE-----EKMQEQE-------EKMWEQEEKMREQEEK 161
             + E++ EQ E++++Q+E +W+QE     E+++E E       E ++EQ  + R   E+
Sbjct: 275 LDEVEELLEQ-ERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEE 333

Query: 162 MREQEEKMQGQEEKMRDVEPAGG 184
           +  + +     E++++++E +GG
Sbjct: 334 LNNENKSTLQLEQQVKELEKSGG 356



 Score =  108 bits (270), Expect = 4e-24
 Identities = 65/198 (32%), Positives = 120/198 (60%), Gaps = 13/198 (6%)

Query: 1   MREEERMREREKKMREEEEMM-----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 55
           +R+E     R+ +   E   M     R QEE+++EQEE++REQEE++ EQEE++ EQEE+
Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEER 228

Query: 56  MWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM--REKK 113
           + EQEE++ EQE K+  Q+RL E+ EK+ +Q+ R  E+E  +  +++  +VE++  +E+ 
Sbjct: 229 LREQEERLCEQE-KLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQERL 287

Query: 114 KTQEEKMQEQE-----EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168
           + Q+E++ +QE     E+++E E M+    E + EQ  +     E++  + +   + E++
Sbjct: 288 RQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQ 347

Query: 169 MQGQEEKMRDVEPAGGEA 186
           ++  E+     EP G E+
Sbjct: 348 VKELEKSGGAEEPRGSES 365



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 28/86 (32%), Positives = 57/86 (66%)

Query: 100 QKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 159
           +++  +   +R++ ++   ++Q + E  Q    +   QEE+++EQEE++ EQEE++ EQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQE 219

Query: 160 EKMREQEEKMQGQEEKMRDVEPAGGE 185
           E++ EQEE+++ QEE++ + E   G+
Sbjct: 220 ERLCEQEERLREQEERLCEQEKLPGQ 245


>gi|154937324 hypothetical protein LOC440295 [Homo sapiens]
          Length = 432

 Score =  113 bits (282), Expect = 2e-25
 Identities = 67/190 (35%), Positives = 117/190 (61%), Gaps = 9/190 (4%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+EER+RE+E+++RE+EE + EQEE++ EQEE++REQEE++ EQE+     +E++ E+ E
Sbjct: 196 RQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEK--LPGQERLLEEVE 253

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121
           K+ +QE +  EQ+RL E++  + E +E L ++  R +++++WQQ E +RE      E+++
Sbjct: 254 KLLKQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQ-ETLREL-----ERLR 307

Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEP 181
           E E  ++   E ++EQ  + +   E++   E K   Q E+  ++ EK  G EE       
Sbjct: 308 ELERMLELGWEALYEQRAEPRSGFEEL-NNENKSTLQLEQQVKELEKSGGAEEPRGSESA 366

Query: 182 AGGEAGEGSP 191
           A      G+P
Sbjct: 367 AAARPVPGAP 376



 Score =  108 bits (270), Expect = 4e-24
 Identities = 66/203 (32%), Positives = 124/203 (61%), Gaps = 29/203 (14%)

Query: 5   ERMREREKKMREEEEMMREQEEKMQE-----------QEEKMREQEEKMWEQEEKMQEQE 53
           E++++    +R+E E +  Q +   E           QEE++REQEE++ EQEE++ EQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQE 219

Query: 54  EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113
           E++ EQEE++ EQEE++ EQ++LP Q E++ E+ E+L ++E R  EQ+   +    RE+ 
Sbjct: 220 ERLCEQEERLREQEERLCEQEKLPGQ-ERLLEEVEKLLKQERRQEEQERLLE----RERL 274

Query: 114 KTQEEKMQEQEEKMQEQEEMMWEQE-----EKMQEQE-------EKMWEQEEKMREQEEK 161
             + E++ EQ E++++Q+E +W+QE     E+++E E       E ++EQ  + R   E+
Sbjct: 275 LDEVEELLEQ-ERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEE 333

Query: 162 MREQEEKMQGQEEKMRDVEPAGG 184
           +  + +     E++++++E +GG
Sbjct: 334 LNNENKSTLQLEQQVKELEKSGG 356



 Score =  108 bits (270), Expect = 4e-24
 Identities = 65/198 (32%), Positives = 120/198 (60%), Gaps = 13/198 (6%)

Query: 1   MREEERMREREKKMREEEEMM-----REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 55
           +R+E     R+ +   E   M     R QEE+++EQEE++REQEE++ EQEE++ EQEE+
Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEER 228

Query: 56  MWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM--REKK 113
           + EQEE++ EQE K+  Q+RL E+ EK+ +Q+ R  E+E  +  +++  +VE++  +E+ 
Sbjct: 229 LREQEERLCEQE-KLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQERL 287

Query: 114 KTQEEKMQEQE-----EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168
           + Q+E++ +QE     E+++E E M+    E + EQ  +     E++  + +   + E++
Sbjct: 288 RQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQ 347

Query: 169 MQGQEEKMRDVEPAGGEA 186
           ++  E+     EP G E+
Sbjct: 348 VKELEKSGGAEEPRGSES 365



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 28/86 (32%), Positives = 57/86 (66%)

Query: 100 QKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 159
           +++  +   +R++ ++   ++Q + E  Q    +   QEE+++EQEE++ EQEE++ EQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQE 219

Query: 160 EKMREQEEKMQGQEEKMRDVEPAGGE 185
           E++ EQEE+++ QEE++ + E   G+
Sbjct: 220 ERLCEQEERLREQEERLCEQEKLPGQ 245


>gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 432

 Score =  112 bits (281), Expect = 2e-25
 Identities = 67/190 (35%), Positives = 116/190 (61%), Gaps = 9/190 (4%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           R+EER+RE+E+++RE+EE + EQEE++ EQEE++ EQEE++ EQE+     +E++ E+ E
Sbjct: 196 RQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEK--LPGQERLLEEVE 253

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121
           K+ EQE +  EQ+RL E++  + E +E L ++  R +++++WQQ E +RE      E+++
Sbjct: 254 KLLEQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQ-ETLREL-----ERLR 307

Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEP 181
           E E  ++   E ++EQ  + +   E++   E K   Q E+  ++ EK  G EE       
Sbjct: 308 ELERMLELGWEALYEQRAEPRSGFEEL-NNENKSTLQLEQQVKELEKSGGAEEPRGSESA 366

Query: 182 AGGEAGEGSP 191
           A      G+P
Sbjct: 367 AAARPVPGAP 376



 Score =  111 bits (278), Expect = 5e-25
 Identities = 67/203 (33%), Positives = 124/203 (61%), Gaps = 29/203 (14%)

Query: 5   ERMREREKKMREEEEMMREQEEKMQE-----------QEEKMREQEEKMWEQEEKMQEQE 53
           E++++    +R+E E +  Q +   E           QEE++REQEE++ EQEE++ EQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQE 219

Query: 54  EKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKK 113
           E++ EQEE++ EQEE++ EQ++LP Q E++ E+ E+L E+E R  EQ+   +    RE+ 
Sbjct: 220 ERLCEQEERLCEQEERLCEQEKLPGQ-ERLLEEVEKLLEQERRQEEQERLLE----RERL 274

Query: 114 KTQEEKMQEQEEKMQEQEEMMWEQE-----EKMQEQE-------EKMWEQEEKMREQEEK 161
             + E++ EQ E++++Q+E +W+QE     E+++E E       E ++EQ  + R   E+
Sbjct: 275 LDEVEELLEQ-ERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEE 333

Query: 162 MREQEEKMQGQEEKMRDVEPAGG 184
           +  + +     E++++++E +GG
Sbjct: 334 LNNENKSTLQLEQQVKELEKSGG 356



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 28/86 (32%), Positives = 56/86 (65%)

Query: 100 QKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 159
           +++  +   +R++ ++   ++Q + E  Q    +   QEE+++EQEE++ EQEE++ EQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQE 219

Query: 160 EKMREQEEKMQGQEEKMRDVEPAGGE 185
           E++ EQEE++  QEE++ + E   G+
Sbjct: 220 ERLCEQEERLCEQEERLCEQEKLPGQ 245



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 32/128 (25%), Positives = 70/128 (54%), Gaps = 18/128 (14%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
           + E E++ E+E++  EE+E + E+E  + E EE +         ++E++++Q+E++W+QE
Sbjct: 249 LEEVEKLLEQERRQ-EEQERLLERERLLDEVEELL---------EQERLRQQDERLWQQE 298

Query: 61  EKMWEQEEKMWEQQRLPEQK-EKMWEQDERLREKEERMREQ-----KMWQQVEKMREKKK 114
                + E++ E +R+ E   E ++EQ    R   E +  +     ++ QQV+++ +   
Sbjct: 299 --TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGG 356

Query: 115 TQEEKMQE 122
            +E +  E
Sbjct: 357 AEEPRGSE 364



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 12/100 (12%)

Query: 93  KEERMREQKMWQQVEKMREKKKTQEEKMQEQE--------EKMQEQEEMMWEQEEKMQEQ 144
           KEE+  E  + Q++ +   K K Q  +    E        E++Q++   + ++ E +  Q
Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179

Query: 145 EEKMWEQEEKM----REQEEKMREQEEKMQGQEEKMRDVE 180
            +   E  + +    R QEE++REQEE+++ QEE++ + E
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQE 219


>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
           sapiens]
          Length = 693

 Score =  104 bits (260), Expect = 6e-23
 Identities = 65/209 (31%), Positives = 124/209 (59%), Gaps = 22/209 (10%)

Query: 5   ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 64
           E++++  K +R+E E +   E K+Q Q E  +       EQ++++QEQEE + EQE +  
Sbjct: 298 EQLQDEAKHLRQEVEGL---EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRV 354

Query: 65  EQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
            ++E++ EQ +RL EQ++ + EQ ERLR++E+R+R+Q+         E+ + +EE++Q+Q
Sbjct: 355 REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE---------ERLRKEEERLQKQ 405

Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKM-WEQEEKMREQ--------EEKMREQEEKMQGQEE 174
           E+++ +QEE +W++EE++Q+QEE++   Q  K+ +Q        E+   E++  +Q +++
Sbjct: 406 EKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQ 465

Query: 175 KMRDVEPAGGEAGEGSPQDNPTAQEIMQL 203
                E    E  E + Q N   +  + L
Sbjct: 466 VKELQEKLDEEHLEAASQQNQQLETQLSL 494



 Score =  101 bits (252), Expect = 5e-22
 Identities = 56/209 (26%), Positives = 122/209 (58%), Gaps = 29/209 (13%)

Query: 8   REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67
           +E++++++E+EEM+REQE +   ++E++ EQ E++ EQ++ +QEQ E++ +QE+++ +QE
Sbjct: 333 KEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE 392

Query: 68  EKM-WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEK 126
           E++  E++RL +Q++++W+Q+ERL +KEER+++Q               +E     Q  K
Sbjct: 393 ERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQ---------------EERLALSQNHK 437

Query: 127 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE------ 180
           + +Q        E +  +++   + E++++E +EK+ E+  +   Q+ +  + +      
Sbjct: 438 LDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQLSLVAL 497

Query: 181 PAGGEAG-------EGSPQDNPTAQEIMQ 202
           P  G+ G       E +P+  P   E ++
Sbjct: 498 PGEGDGGQHLDSEEEEAPRPTPNIPEDLE 526



 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 59/196 (30%), Positives = 125/196 (63%), Gaps = 26/196 (13%)

Query: 3   EEERMREREKKMREEEEMMREQEEK----MQEQEEKMREQEEKMWEQE-----------E 47
           E  R +ER  KM  E   ++E++++    +QE E  + E + +M +             E
Sbjct: 239 ERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVE 298

Query: 48  KMQEQEEKMWEQEEKMWEQEEKMWEQQRL-----PEQKEKMWEQDERLREKE-ERMREQ- 100
           ++Q++ + + ++ E +  + +   E  +       EQK+++ EQ+E LRE+E +R+REQ 
Sbjct: 299 QLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQE 358

Query: 101 KMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160
           ++ +Q E++RE++KT    +QEQ E++++QE+ + +QEE+++++EE++ +QE+++ +QEE
Sbjct: 359 RLCEQNERLREQQKT----LQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEE 414

Query: 161 KMREQEEKMQGQEEKM 176
           ++ ++EE++Q QEE++
Sbjct: 415 RLWKKEERLQKQEERL 430



 Score = 97.4 bits (241), Expect = 9e-21
 Identities = 44/156 (28%), Positives = 107/156 (68%), Gaps = 6/156 (3%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
           +EE +RE+E +   E+E + EQ E+++EQ++ ++EQ E++ +QE+++++QEE++ ++EE+
Sbjct: 342 QEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEER 401

Query: 63  MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQE 122
           + +QE+++W+Q+      E++W+++ERL+++EER+   +  +  +++ E + + E+   E
Sbjct: 402 LQKQEKRLWDQE------ERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNE 455

Query: 123 QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 158
           ++  +Q ++++   QE+  +E  E   +Q +++  Q
Sbjct: 456 KKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQ 491



 Score = 97.1 bits (240), Expect = 1e-20
 Identities = 59/195 (30%), Positives = 120/195 (61%), Gaps = 21/195 (10%)

Query: 2   REEERMREREKKMREEEEMMREQE-----------EKMQEQEEKMREQEE----KMWEQE 46
           R+  R++E E+ + E +  M +             E++Q++ + +R++ E    K+  Q 
Sbjct: 263 RDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQV 322

Query: 47  EKMQEQEEKMWEQEEKMWEQEEKMWEQ--QRLPEQKEKMWEQDERLREKEERMREQKMWQ 104
           E  Q       EQ++++ EQEE + EQ  QR+ EQ E++ EQ+ERLRE+++ ++EQ   +
Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQ-ERLCEQNERLREQQKTLQEQ--GE 379

Query: 105 QVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-EQEEKMR 163
           ++ K  ++ + QEE+++++EE++Q+QE+ +W+QEE++ ++EE++ +QEE++   Q  K+ 
Sbjct: 380 RLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLD 439

Query: 164 EQEEKMQGQEEKMRD 178
           +Q  + Q   E + +
Sbjct: 440 KQLAEPQCSFEDLNN 454



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 66/305 (21%), Positives = 125/305 (40%), Gaps = 104/305 (34%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE--------------- 46
           ++E+R+R++E+++R+EEE +++QE+++ +QEE++ ++EE++ +QE               
Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQL 442

Query: 47  -------EKMQEQEEKMWEQEEKMWEQEEKMWEQ-------------------------- 73
                  E +  +++   + E+++ E +EK+ E+                          
Sbjct: 443 AEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQLSLVALPGEGD 502

Query: 74  --QRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEK------------ 108
             Q L  ++E+       + E  E       +           +QVE+            
Sbjct: 503 GGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQVERRELGFVQPSGVT 562

Query: 109 --MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM------REQEE 160
             MRE     E +      + QE E+++    +K +E + K+ E +E +       E   
Sbjct: 563 DGMRESFTVYESQGAVPNTRHQEMEDVI-RLAQKEEEMKVKLLELQELVLPLVGNHEGHG 621

Query: 161 KM----------------REQEEKMQGQEEKM------RDVEPAGGEAGEGSPQDNPTAQ 198
           K                   QE    G+++         +VEPA G A EGSP DNPT Q
Sbjct: 622 KFLIAAQNPADEPTPGAPAPQELGAAGEQDDFYEVSLDNNVEPAPGAAREGSPHDNPTVQ 681

Query: 199 EIMQL 203
           +I+QL
Sbjct: 682 QIVQL 686



 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 42/188 (22%), Positives = 92/188 (48%), Gaps = 2/188 (1%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE- 60
           RE    R  ++ ++E   +     +  +  ++   E++E     + +    +E+MW+   
Sbjct: 193 REAVLHRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSV 252

Query: 61  EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
           E    +EEK  +  R+ E +  + E   ++  K   +    +   VE+++++ K   +++
Sbjct: 253 EARTLKEEKKRDIHRIQELERSLSELKNQMA-KPPSLAPPAVTSVVEQLQDEAKHLRQEV 311

Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
           +  E K+Q Q E         +EQ++++ EQEE +REQE +   ++E++  Q E++R+ +
Sbjct: 312 EGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQ 371

Query: 181 PAGGEAGE 188
               E GE
Sbjct: 372 KTLQEQGE 379



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 27/178 (15%), Positives = 78/178 (43%), Gaps = 2/178 (1%)

Query: 4   EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63
           E ++ E +K   E  +   E+ E +     +  + +  ++  +   +  EE+  +   ++
Sbjct: 103 EHQLEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRL 162

Query: 64  WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
               +++ E +R         ++++R     E +  +++ QQ  K R        ++ E 
Sbjct: 163 QYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLHRRL-QQTIKERALLNAHVTQVTES 221

Query: 124 EEKMQ-EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
            +++Q E++E     + +    +E+MW+   + R  +E+ +    ++Q  E  + +++
Sbjct: 222 LKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELK 279


>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
           sapiens]
          Length = 693

 Score =  104 bits (259), Expect = 8e-23
 Identities = 65/209 (31%), Positives = 124/209 (59%), Gaps = 22/209 (10%)

Query: 5   ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 64
           E++++  K +R+E E +   E K+Q Q E  +       EQ++++QEQEE + EQE +  
Sbjct: 298 EQLQDEAKHLRQEVEGL---EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRV 354

Query: 65  EQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
            ++E++ EQ +RL EQ++ + EQ ERLR++E+R+R+Q+         E+ + +EE++Q+Q
Sbjct: 355 REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE---------ERLRKEEERLQKQ 405

Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKM-WEQEEKMREQ--------EEKMREQEEKMQGQEE 174
           E+++ +QEE +W++EE++Q+QEE++   Q  K+ +Q        E+   E++  +Q +++
Sbjct: 406 EKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQ 465

Query: 175 KMRDVEPAGGEAGEGSPQDNPTAQEIMQL 203
                E    E  E + Q N   +  + L
Sbjct: 466 VKELQEKLDEEHLEAASQRNQQLETQLSL 494



 Score =  101 bits (252), Expect = 5e-22
 Identities = 59/204 (28%), Positives = 125/204 (61%), Gaps = 19/204 (9%)

Query: 8   REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67
           +E++++++E+EEM+REQE +   ++E++ EQ E++ EQ++ +QEQ E++ +QE+++ +QE
Sbjct: 333 KEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE 392

Query: 68  EKM-WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEK 126
           E++  E++RL +Q++++W+Q+ERL +KEER+++Q+             +Q  K+ +Q  +
Sbjct: 393 ERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQE--------ERLALSQNHKLDKQLAE 444

Query: 127 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE-PAGGE 185
            Q   E +  +++   + E+++ E +EK+   EE +    ++ Q  E ++  V  P  G+
Sbjct: 445 PQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASQRNQQLETQLSLVALPGEGD 502

Query: 186 AG-------EGSPQDNPTAQEIMQ 202
            G       E +P+  P   E ++
Sbjct: 503 GGQHLDSEEEEAPRPTPNIPEDLE 526



 Score = 99.4 bits (246), Expect = 2e-21
 Identities = 60/196 (30%), Positives = 125/196 (63%), Gaps = 26/196 (13%)

Query: 3   EEERMREREKKMREEEEMMREQEEK----MQEQEEKMREQEEKMWEQE-----------E 47
           E  R +ER  KM  E   ++E++++    +QE E  + E + +M E             E
Sbjct: 239 ERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVE 298

Query: 48  KMQEQEEKMWEQEEKMWEQEEKMWEQQRL-----PEQKEKMWEQDERLREKE-ERMREQ- 100
           ++Q++ + + ++ E +  + +   E  +       EQK+++ EQ+E LRE+E +R+REQ 
Sbjct: 299 QLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQE 358

Query: 101 KMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160
           ++ +Q E++RE++KT    +QEQ E++++QE+ + +QEE+++++EE++ +QE+++ +QEE
Sbjct: 359 RLCEQNERLREQQKT----LQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEE 414

Query: 161 KMREQEEKMQGQEEKM 176
           ++ ++EE++Q QEE++
Sbjct: 415 RLWKKEERLQKQEERL 430



 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 60/195 (30%), Positives = 120/195 (61%), Gaps = 21/195 (10%)

Query: 2   REEERMREREKKMREEEEMMREQE-----------EKMQEQEEKMREQEE----KMWEQE 46
           R+  R++E E+ + E +  M E             E++Q++ + +R++ E    K+  Q 
Sbjct: 263 RDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQV 322

Query: 47  EKMQEQEEKMWEQEEKMWEQEEKMWEQ--QRLPEQKEKMWEQDERLREKEERMREQKMWQ 104
           E  Q       EQ++++ EQEE + EQ  QR+ EQ E++ EQ+ERLRE+++ ++EQ   +
Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQ-ERLCEQNERLREQQKTLQEQ--GE 379

Query: 105 QVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-EQEEKMR 163
           ++ K  ++ + QEE+++++EE++Q+QE+ +W+QEE++ ++EE++ +QEE++   Q  K+ 
Sbjct: 380 RLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLD 439

Query: 164 EQEEKMQGQEEKMRD 178
           +Q  + Q   E + +
Sbjct: 440 KQLAEPQCSFEDLNN 454



 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 44/157 (28%), Positives = 111/157 (70%), Gaps = 1/157 (0%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
           +++R++E+E+ +RE+E     ++E++ EQ E++REQ++ + EQ E++++QE+++ +QEE+
Sbjct: 335 QKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEER 394

Query: 63  MWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121
           + ++EE++ +Q+ RL +Q+E++W+++ERL+++EER+   +  +  +++ E + + E+   
Sbjct: 395 LRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNN 454

Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 158
           E++  +Q ++++   QE+  +E  E   ++ +++  Q
Sbjct: 455 EKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQ 491



 Score = 94.4 bits (233), Expect = 8e-20
 Identities = 59/212 (27%), Positives = 123/212 (58%), Gaps = 34/212 (16%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
           +RE+ER+ E+ +++RE+++ ++EQ E++++QE+++R+QEE++ ++EE++Q+QE+++W+QE
Sbjct: 354 VREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQE 413

Query: 61  EKMWEQEEKMWEQ-QRLP-EQKEKMWEQDERLREKE--------ERMREQKMWQQVEKMR 110
           E++W++EE++ +Q +RL   Q  K+   D++L E +        E+    ++ QQV++++
Sbjct: 414 ERLWKKEERLQKQEERLALSQNHKL---DKQLAEPQCSFEDLNNEKKSALQLEQQVKELQ 470

Query: 111 EKKKTQEEKMQEQEEKMQEQE---------------EMMWEQEEKMQEQEEKMWEQEEKM 155
           E  K  EE ++   ++ Q+ E               + +  +EE+       + E  E  
Sbjct: 471 E--KLDEEHLEAASQRNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESR 528

Query: 156 REQEEKMREQEEKMQGQEEKMRD----VEPAG 183
                 M   +EK  G E+  R     V+P+G
Sbjct: 529 EATSSFMDLPKEKADGTEQVERRELGFVQPSG 560



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 42/188 (22%), Positives = 92/188 (48%), Gaps = 2/188 (1%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE- 60
           RE    R  ++ ++E   +     +  +  ++   E++E     + +    +E+MW+   
Sbjct: 193 REAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSV 252

Query: 61  EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
           E    +EEK  +  R+ E +  + E   ++ E    +    +   VE+++++ K   +++
Sbjct: 253 EARTLKEEKKRDIHRIQELERSLSELKNQMAEPPS-LAPPAVTSVVEQLQDEAKHLRQEV 311

Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
           +  E K+Q Q E         +EQ++++ EQEE +REQE +   ++E++  Q E++R+ +
Sbjct: 312 EGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQ 371

Query: 181 PAGGEAGE 188
               E GE
Sbjct: 372 KTLQEQGE 379



 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 65/305 (21%), Positives = 125/305 (40%), Gaps = 104/305 (34%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE--------------- 46
           ++E+R+R++E+++R+EEE +++QE+++ +QEE++ ++EE++ +QE               
Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQL 442

Query: 47  -------EKMQEQEEKMWEQEEKMWEQEEKMWEQ-------------------------- 73
                  E +  +++   + E+++ E +EK+ E+                          
Sbjct: 443 AEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSLVALPGEGD 502

Query: 74  --QRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEK------------ 108
             Q L  ++E+       + E  E       +           +QVE+            
Sbjct: 503 GGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQVERRELGFVQPSGVT 562

Query: 109 --MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM------REQEE 160
             MRE     E +      + QE E+++    +K +E + K+ E +E +       E   
Sbjct: 563 DGMRESFTVYESQGAVPNTRHQEMEDVI-RLAQKEEEMKVKLLELQELVLPLVGNHEGHG 621

Query: 161 KM----------------REQEEKMQGQEEKM------RDVEPAGGEAGEGSPQDNPTAQ 198
           K                   QE    G+++         +VEPA G A EGSP +NPT Q
Sbjct: 622 KFLIAAQNPADEPTPGAPAPQELGAAGEQDVFYEVSLDNNVEPAPGVAREGSPHNNPTVQ 681

Query: 199 EIMQL 203
           +I+QL
Sbjct: 682 QIVQL 686



 Score = 32.3 bits (72), Expect = 0.37
 Identities = 32/200 (16%), Positives = 85/200 (42%), Gaps = 2/200 (1%)

Query: 4   EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63
           E ++ E +K   E  +   EQ E +     +  + +  ++  +   +  EE+  +   ++
Sbjct: 103 EHQLEEAKKTNNEIHKAQMEQLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRL 162

Query: 64  WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
               + + E +R         ++++R     E + ++++ QQ  K R        ++ E 
Sbjct: 163 QYSLQHIQELERALCAVSTQQQEEDRSSSCREAVLQRRL-QQTIKERALLNAHVTQVTES 221

Query: 124 EEKMQ-EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPA 182
            +++Q E++E     + +    +E+MW+   + R  +E+ +    ++Q  E  + +++  
Sbjct: 222 LKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQ 281

Query: 183 GGEAGEGSPQDNPTAQEIMQ 202
             E    +P    +  E +Q
Sbjct: 282 MAEPPSLAPPAVTSVVEQLQ 301


>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
           isoform 1 [Homo sapiens]
          Length = 693

 Score =  104 bits (259), Expect = 8e-23
 Identities = 65/209 (31%), Positives = 124/209 (59%), Gaps = 22/209 (10%)

Query: 5   ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 64
           E++++  K +R+E E +   E K+Q Q E  +       EQ++++QEQEE + EQE +  
Sbjct: 298 EQLQDEAKHLRQEVEGL---EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRV 354

Query: 65  EQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
            ++E++ EQ +RL EQ++ + EQ ERLR++E+R+R+Q+         E+ + +EE++Q+Q
Sbjct: 355 REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE---------ERLRKEEERLQKQ 405

Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKM-WEQEEKMREQ--------EEKMREQEEKMQGQEE 174
           E+++ +QEE +W++EE++Q+QEE++   Q  K+ +Q        E+   E++  +Q +++
Sbjct: 406 EKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQ 465

Query: 175 KMRDVEPAGGEAGEGSPQDNPTAQEIMQL 203
                E    E  E + Q N   +  + L
Sbjct: 466 VKELQEKLDEEHLEAASQRNQQLETQLSL 494



 Score =  101 bits (252), Expect = 5e-22
 Identities = 59/204 (28%), Positives = 125/204 (61%), Gaps = 19/204 (9%)

Query: 8   REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67
           +E++++++E+EEM+REQE +   ++E++ EQ E++ EQ++ +QEQ E++ +QE+++ +QE
Sbjct: 333 KEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE 392

Query: 68  EKM-WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEK 126
           E++  E++RL +Q++++W+Q+ERL +KEER+++Q+             +Q  K+ +Q  +
Sbjct: 393 ERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQE--------ERLALSQNHKLDKQLAE 444

Query: 127 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE-PAGGE 185
            Q   E +  +++   + E+++ E +EK+   EE +    ++ Q  E ++  V  P  G+
Sbjct: 445 PQCSFEDLNNEKKSALQLEQQVKELQEKL--DEEHLEAASQRNQQLETQLSLVALPGEGD 502

Query: 186 AG-------EGSPQDNPTAQEIMQ 202
            G       E +P+  P   E ++
Sbjct: 503 GGQHLDSEEEEAPRPTPNIPEDLE 526



 Score = 99.4 bits (246), Expect = 2e-21
 Identities = 60/196 (30%), Positives = 125/196 (63%), Gaps = 26/196 (13%)

Query: 3   EEERMREREKKMREEEEMMREQEEK----MQEQEEKMREQEEKMWEQE-----------E 47
           E  R +ER  KM  E   ++E++++    +QE E  + E + +M E             E
Sbjct: 239 ERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVE 298

Query: 48  KMQEQEEKMWEQEEKMWEQEEKMWEQQRL-----PEQKEKMWEQDERLREKE-ERMREQ- 100
           ++Q++ + + ++ E +  + +   E  +       EQK+++ EQ+E LRE+E +R+REQ 
Sbjct: 299 QLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQE 358

Query: 101 KMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160
           ++ +Q E++RE++KT    +QEQ E++++QE+ + +QEE+++++EE++ +QE+++ +QEE
Sbjct: 359 RLCEQNERLREQQKT----LQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEE 414

Query: 161 KMREQEEKMQGQEEKM 176
           ++ ++EE++Q QEE++
Sbjct: 415 RLWKKEERLQKQEERL 430



 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 60/195 (30%), Positives = 120/195 (61%), Gaps = 21/195 (10%)

Query: 2   REEERMREREKKMREEEEMMREQE-----------EKMQEQEEKMREQEE----KMWEQE 46
           R+  R++E E+ + E +  M E             E++Q++ + +R++ E    K+  Q 
Sbjct: 263 RDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQV 322

Query: 47  EKMQEQEEKMWEQEEKMWEQEEKMWEQ--QRLPEQKEKMWEQDERLREKEERMREQKMWQ 104
           E  Q       EQ++++ EQEE + EQ  QR+ EQ E++ EQ+ERLRE+++ ++EQ   +
Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQ-ERLCEQNERLREQQKTLQEQ--GE 379

Query: 105 QVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-EQEEKMR 163
           ++ K  ++ + QEE+++++EE++Q+QE+ +W+QEE++ ++EE++ +QEE++   Q  K+ 
Sbjct: 380 RLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLD 439

Query: 164 EQEEKMQGQEEKMRD 178
           +Q  + Q   E + +
Sbjct: 440 KQLAEPQCSFEDLNN 454



 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 44/157 (28%), Positives = 111/157 (70%), Gaps = 1/157 (0%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
           +++R++E+E+ +RE+E     ++E++ EQ E++REQ++ + EQ E++++QE+++ +QEE+
Sbjct: 335 QKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEER 394

Query: 63  MWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121
           + ++EE++ +Q+ RL +Q+E++W+++ERL+++EER+   +  +  +++ E + + E+   
Sbjct: 395 LRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNN 454

Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 158
           E++  +Q ++++   QE+  +E  E   ++ +++  Q
Sbjct: 455 EKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQ 491



 Score = 94.4 bits (233), Expect = 8e-20
 Identities = 59/212 (27%), Positives = 123/212 (58%), Gaps = 34/212 (16%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
           +RE+ER+ E+ +++RE+++ ++EQ E++++QE+++R+QEE++ ++EE++Q+QE+++W+QE
Sbjct: 354 VREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQE 413

Query: 61  EKMWEQEEKMWEQ-QRLP-EQKEKMWEQDERLREKE--------ERMREQKMWQQVEKMR 110
           E++W++EE++ +Q +RL   Q  K+   D++L E +        E+    ++ QQV++++
Sbjct: 414 ERLWKKEERLQKQEERLALSQNHKL---DKQLAEPQCSFEDLNNEKKSALQLEQQVKELQ 470

Query: 111 EKKKTQEEKMQEQEEKMQEQE---------------EMMWEQEEKMQEQEEKMWEQEEKM 155
           E  K  EE ++   ++ Q+ E               + +  +EE+       + E  E  
Sbjct: 471 E--KLDEEHLEAASQRNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESR 528

Query: 156 REQEEKMREQEEKMQGQEEKMRD----VEPAG 183
                 M   +EK  G E+  R     V+P+G
Sbjct: 529 EATSSFMDLPKEKADGTEQVERRELGFVQPSG 560



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 42/188 (22%), Positives = 92/188 (48%), Gaps = 2/188 (1%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE- 60
           RE    R  ++ ++E   +     +  +  ++   E++E     + +    +E+MW+   
Sbjct: 193 REAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSV 252

Query: 61  EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
           E    +EEK  +  R+ E +  + E   ++ E    +    +   VE+++++ K   +++
Sbjct: 253 EARTLKEEKKRDIHRIQELERSLSELKNQMAEPPS-LAPPAVTSVVEQLQDEAKHLRQEV 311

Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
           +  E K+Q Q E         +EQ++++ EQEE +REQE +   ++E++  Q E++R+ +
Sbjct: 312 EGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQ 371

Query: 181 PAGGEAGE 188
               E GE
Sbjct: 372 KTLQEQGE 379



 Score = 58.2 bits (139), Expect = 6e-09
 Identities = 65/305 (21%), Positives = 124/305 (40%), Gaps = 104/305 (34%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE--------------- 46
           ++E+R+R++E+++R+EEE +++QE+++ +QEE++ ++EE++ +QE               
Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQL 442

Query: 47  -------EKMQEQEEKMWEQEEKMWEQEEKMWEQ-------------------------- 73
                  E +  +++   + E+++ E +EK+ E+                          
Sbjct: 443 AEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSLVALPGEGD 502

Query: 74  --QRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEK------------ 108
             Q L  ++E+       + E  E       +           +QVE+            
Sbjct: 503 GGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQVERRELGFVQPSGVT 562

Query: 109 --MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM------REQEE 160
             MRE     E +      + QE E+++    +K +E + K+ E +E +       E   
Sbjct: 563 DGMRESFTVYESQGAVPNTRHQEMEDVI-RLAQKEEEMKVKLLELQELVLPLVGNHEGHG 621

Query: 161 KM----------------REQEEKMQGQEEKM------RDVEPAGGEAGEGSPQDNPTAQ 198
           K                   QE    G+++         +VEPA G A EGSP DNP  Q
Sbjct: 622 KFLIAAQNPADEPTPGAPAPQELGAAGEQDDFYEVSLDNNVEPAPGAAREGSPHDNPPVQ 681

Query: 199 EIMQL 203
           +I+QL
Sbjct: 682 QIVQL 686



 Score = 35.0 bits (79), Expect = 0.057
 Identities = 32/200 (16%), Positives = 86/200 (43%), Gaps = 2/200 (1%)

Query: 4   EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63
           E ++ E +K   E  +   EQ E +     +  + +  ++  +   +  EE+  +   ++
Sbjct: 103 EHQLEEAKKTNNEIHKAQMEQLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRL 162

Query: 64  WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
               +++ E +R         ++++R     E + ++++ QQ  K R        ++ E 
Sbjct: 163 QYSLQRIQELERALSAVSTQQQEEDRSSSCREAVLQRRL-QQTIKERALLNAHVTQVTES 221

Query: 124 EEKMQ-EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPA 182
            +++Q E++E     + +    +E+MW+   + R  +E+ +    ++Q  E  + +++  
Sbjct: 222 LKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQ 281

Query: 183 GGEAGEGSPQDNPTAQEIMQ 202
             E    +P    +  E +Q
Sbjct: 282 MAEPPSLAPPAVTSVVEQLQ 301


>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
           sapiens]
          Length = 693

 Score =  103 bits (257), Expect = 1e-22
 Identities = 58/178 (32%), Positives = 114/178 (64%), Gaps = 14/178 (7%)

Query: 5   ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 64
           E++++  K +R+E E +   E K+Q Q E  +       EQ++++QEQEE + EQE +  
Sbjct: 298 EQLQDEAKHLRQEVEGL---EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRV 354

Query: 65  EQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
            ++E++ EQ +RL EQ++ + EQ ERLR++E+R+R+Q+         E+ + +EE++Q+Q
Sbjct: 355 REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE---------ERLRKEEERLQKQ 405

Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKM-WEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
           E+++ +QEE +W++EE++Q+QEE++   Q  K+ +Q  + +   E +  +++    +E
Sbjct: 406 EKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLE 463



 Score =  100 bits (250), Expect = 8e-22
 Identities = 58/204 (28%), Positives = 125/204 (61%), Gaps = 19/204 (9%)

Query: 8   REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67
           +E++++++E+EEM+REQE +   ++E++ EQ E++ EQ++ +QEQ E++ +QE+++ +QE
Sbjct: 333 KEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQE 392

Query: 68  EKM-WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEK 126
           E++  E++RL +Q++++W+Q+ERL +KEER+++Q+             +Q  K+ +Q  +
Sbjct: 393 ERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQE--------ERLALSQNHKLDKQLAE 444

Query: 127 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE-EKMREQEEKMQGQEEKMRDVEPAGGE 185
            Q   E +  +++   + E+++ E +EK+ E+  E    Q ++++ Q   +    P  G+
Sbjct: 445 PQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASHQNQQLETQLSLV--ALPGEGD 502

Query: 186 AG-------EGSPQDNPTAQEIMQ 202
            G       E +P+  P   E ++
Sbjct: 503 GGQHLDSEEEEAPRPTPNIPEDLE 526



 Score = 99.4 bits (246), Expect = 2e-21
 Identities = 60/196 (30%), Positives = 125/196 (63%), Gaps = 26/196 (13%)

Query: 3   EEERMREREKKMREEEEMMREQEEK----MQEQEEKMREQEEKMWEQE-----------E 47
           E  R +ER  KM  E   ++E++++    +QE E  + E + +M E             E
Sbjct: 239 ERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVE 298

Query: 48  KMQEQEEKMWEQEEKMWEQEEKMWEQQRL-----PEQKEKMWEQDERLREKE-ERMREQ- 100
           ++Q++ + + ++ E +  + +   E  +       EQK+++ EQ+E LRE+E +R+REQ 
Sbjct: 299 QLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQE 358

Query: 101 KMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160
           ++ +Q E++RE++KT    +QEQ E++++QE+ + +QEE+++++EE++ +QE+++ +QEE
Sbjct: 359 RLCEQNERLREQQKT----LQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEE 414

Query: 161 KMREQEEKMQGQEEKM 176
           ++ ++EE++Q QEE++
Sbjct: 415 RLWKKEERLQKQEERL 430



 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 60/195 (30%), Positives = 120/195 (61%), Gaps = 21/195 (10%)

Query: 2   REEERMREREKKMREEEEMMREQE-----------EKMQEQEEKMREQEE----KMWEQE 46
           R+  R++E E+ + E +  M E             E++Q++ + +R++ E    K+  Q 
Sbjct: 263 RDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQV 322

Query: 47  EKMQEQEEKMWEQEEKMWEQEEKMWEQ--QRLPEQKEKMWEQDERLREKEERMREQKMWQ 104
           E  Q       EQ++++ EQEE + EQ  QR+ EQ E++ EQ+ERLRE+++ ++EQ   +
Sbjct: 323 ENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQ-ERLCEQNERLREQQKTLQEQ--GE 379

Query: 105 QVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR-EQEEKMR 163
           ++ K  ++ + QEE+++++EE++Q+QE+ +W+QEE++ ++EE++ +QEE++   Q  K+ 
Sbjct: 380 RLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLD 439

Query: 164 EQEEKMQGQEEKMRD 178
           +Q  + Q   E + +
Sbjct: 440 KQLAEPQCSFEDLNN 454



 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 45/157 (28%), Positives = 110/157 (70%), Gaps = 1/157 (0%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
           +++R++E+E+ +RE+E     ++E++ EQ E++REQ++ + EQ E++++QE+++ +QEE+
Sbjct: 335 QKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEER 394

Query: 63  MWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121
           + ++EE++ +Q+ RL +Q+E++W+++ERL+++EER+   +  +  +++ E + + E+   
Sbjct: 395 LRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNN 454

Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 158
           E++  +Q ++++   QE+  +E  E    Q +++  Q
Sbjct: 455 EKKSALQLEQQVKELQEKLDEEHLEAASHQNQQLETQ 491



 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 58/210 (27%), Positives = 122/210 (58%), Gaps = 30/210 (14%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
           +RE+ER+ E+ +++RE+++ ++EQ E++++QE+++R+QEE++ ++EE++Q+QE+++W+QE
Sbjct: 354 VREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQE 413

Query: 61  EKMWEQEEKMWEQ-QRLP-EQKEKMWEQDERLREKE--------ERMREQKMWQQVEKMR 110
           E++W++EE++ +Q +RL   Q  K+   D++L E +        E+    ++ QQV++++
Sbjct: 414 ERLWKKEERLQKQEERLALSQNHKL---DKQLAEPQCSFEDLNNEKKSALQLEQQVKELQ 470

Query: 111 EKKKTQE-EKMQEQEEKMQEQEEM------------MWEQEEKMQEQEEKMWEQEEKMRE 157
           EK   +  E    Q ++++ Q  +            +  +EE+       + E  E    
Sbjct: 471 EKLDEEHLEAASHQNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREA 530

Query: 158 QEEKMREQEEKMQGQEEKMRD----VEPAG 183
               M   +EK  G E+  R     V+P+G
Sbjct: 531 TSSFMDLPKEKADGTEQVERRELGFVQPSG 560



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 66/305 (21%), Positives = 125/305 (40%), Gaps = 104/305 (34%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE--------------- 46
           ++E+R+R++E+++R+EEE +++QE+++ +QEE++ ++EE++ +QE               
Sbjct: 383 KQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQL 442

Query: 47  -------EKMQEQEEKMWEQEEKMWEQEEKMWEQ-------------------------- 73
                  E +  +++   + E+++ E +EK+ E+                          
Sbjct: 443 AEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASHQNQQLETQLSLVALPGEGD 502

Query: 74  --QRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEK------------ 108
             Q L  ++E+       + E  E       +           +QVE+            
Sbjct: 503 GGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQVERRELGFVQPSGVT 562

Query: 109 --MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM------REQEE 160
             MRE     E +      + QE E+++    +K +E + K+ E +E +       E   
Sbjct: 563 DGMRESFTVYESQGAVPNTRHQEMEDVI-RLAQKEEEMKVKLLELQELVLPLVGNHEGHG 621

Query: 161 KM----------------REQEEKMQGQEEKM------RDVEPAGGEAGEGSPQDNPTAQ 198
           K                   QE    G+++         +VEPA G A EGSP DNPT Q
Sbjct: 622 KFLIAAQNPADEPTPGAPAPQELGAAGEQDVFYEVSLDNNVEPAPGAAREGSPHDNPTVQ 681

Query: 199 EIMQL 203
           +I+QL
Sbjct: 682 QIVQL 686



 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 42/188 (22%), Positives = 92/188 (48%), Gaps = 2/188 (1%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE- 60
           RE    R  ++ ++E   +     +  +  ++   E++E     + +    +E+MW+   
Sbjct: 193 REAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSV 252

Query: 61  EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
           E    +EEK  +  R+ E +  + E   ++ E    +    +   VE+++++ K   +++
Sbjct: 253 EARTLKEEKKRDIHRIQELERSLSELKNQMAEPPS-LAPPAVTSVVEQLQDEAKHLRQEV 311

Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
           +  E K+Q Q E         +EQ++++ EQEE +REQE +   ++E++  Q E++R+ +
Sbjct: 312 EGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQ 371

Query: 181 PAGGEAGE 188
               E GE
Sbjct: 372 KTLQEQGE 379



 Score = 31.2 bits (69), Expect = 0.82
 Identities = 38/215 (17%), Positives = 93/215 (43%), Gaps = 25/215 (11%)

Query: 13  KMREEEEMMREQEEKMQEQEEKMREQEEKMWE-QEEKMQEQEEKMWEQEE---------- 61
           ++ E  E +++Q+++++ Q E+ ++   ++ + Q E+++       E+ +          
Sbjct: 87  QLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKR 146

Query: 62  --KMWEQEEK------MWEQQRLPEQKEKMW----EQDERLREKEERMREQKMW-QQVEK 108
             + +E+E K       +  QR+ E +  +     +Q E  R    R    + W QQ  K
Sbjct: 147 AARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLQRWLQQTIK 206

Query: 109 MREKKKTQEEKMQEQEEKMQ-EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 167
            R        ++ E  +++Q E++E     + +    +E+MW+   + R  +E+ +    
Sbjct: 207 ERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIH 266

Query: 168 KMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEIMQ 202
           ++Q  E  + +++    E    +P    +  E +Q
Sbjct: 267 RIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQ 301


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 99.8 bits (247), Expect = 2e-21
 Identities = 54/181 (29%), Positives = 117/181 (64%), Gaps = 2/181 (1%)

Query: 1   MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE-QEEKMQEQEEKMWEQ 59
           +RE ER  E  K+ ++E E  R++E + +E+ ++ RE+E K    ++EK  E++++  E+
Sbjct: 38  IREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERER 97

Query: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119
           +++  E+E K  E++   ++KEK  E+    +E +ER R+++  ++  K RE+KK + EK
Sbjct: 98  KKRRREKENKEGEEKEKRKKKEKK-ERGRTSKEGKERERKEERKREERKERERKKEEREK 156

Query: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDV 179
            +E++E+ + + + + E+EE+ +E+E K  ++ E+ R++ +K RE++E+ + ++E+ +  
Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216

Query: 180 E 180
           E
Sbjct: 217 E 217



 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 52/174 (29%), Positives = 114/174 (65%), Gaps = 6/174 (3%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           RE+ER RER KK ++ E   R++EE+  E++++ RE+E K  E++EK +++E+K   +  
Sbjct: 73  REKERKRERGKKEKKGE---RKKEER--ERKKRRREKENKEGEEKEKRKKKEKKERGRTS 127

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121
           K  ++ E+  E++R  E+KE+  +++ER +E+E + R+++  +QV +  E++K +E K +
Sbjct: 128 KEGKERERKEERKR-EERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186

Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175
           ++ E+ +++ +   E++E+ + ++E+  ++E K   Q+++     EK +G+ E+
Sbjct: 187 KKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRER 240



 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 48/167 (28%), Positives = 102/167 (61%), Gaps = 7/167 (4%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM-QEQEEKMWEQEE 61
           ++E+  ER+K+ RE ++  RE+E K  E++EK +++E+K   +  K  +E+E K   + E
Sbjct: 83  KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121
           +  E+E K  E+++  E+KE+   + +++ EKEE  +E+      E+   KK+ +  K +
Sbjct: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEK------ERKERKKRERNRKER 196

Query: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168
           ++E + +E+ E   E+++K + ++E+  +++   RE+E   RE++E+
Sbjct: 197 KKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243



 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 37/146 (25%), Positives = 84/146 (57%), Gaps = 2/146 (1%)

Query: 43  WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKM 102
           W+ E + +E+E +  ++ +K  E E K   ++R   ++E+  E+     +KE++   +K 
Sbjct: 34  WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE 93

Query: 103 WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 162
            ++ +K R +K+ +E + +E+ +K +++E     +E K +E++E+   +E K RE++++ 
Sbjct: 94  ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153

Query: 163 REQEEKMQGQEEKMRDVEPAGGEAGE 188
           RE+E   + +E K R+ +  G +  E
Sbjct: 154 REKER--ERKERKKRERKQVGEKEEE 177



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 29/111 (26%), Positives = 64/111 (57%), Gaps = 11/111 (9%)

Query: 84  WEQDERLREKE-ERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQ 142
           W+ + R RE+E E  +E K  ++ E+ +E+++ ++ K + ++E+ +E+ +       K +
Sbjct: 34  WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK-------KEK 86

Query: 143 EQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQD 193
           + E K  E+E K R +E++ +E EEK   ++ K ++ +  G  + EG  ++
Sbjct: 87  KGERKKEERERKKRRREKENKEGEEK---EKRKKKEKKERGRTSKEGKERE 134



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 24/89 (26%), Positives = 55/89 (61%), Gaps = 8/89 (8%)

Query: 100 QKMWQQVEKMRE-----KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ---EEKMWEQ 151
           Q  WQ   + RE     +K+ ++E+  E++++ +E+E+   E+E++ + +   +EK  E+
Sbjct: 31  QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90

Query: 152 EEKMREQEEKMREQEEKMQGQEEKMRDVE 180
           +++ RE++++ RE+E K   ++EK +  E
Sbjct: 91  KKEERERKKRRREKENKEGEEKEKRKKKE 119



 Score = 31.6 bits (70), Expect = 0.63
 Identities = 21/70 (30%), Positives = 39/70 (55%), Gaps = 1/70 (1%)

Query: 112 KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE-EKMREQEEKMQ 170
           K  TQ     E  E+ +E E     ++E+  E++++  E+E++ RE+E E+ RE+ +K +
Sbjct: 27  KPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEK 86

Query: 171 GQEEKMRDVE 180
             E K  + E
Sbjct: 87  KGERKKEERE 96


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 52/186 (27%), Positives = 118/186 (63%), Gaps = 8/186 (4%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
            +EE ++ + E+K+ +EE  + ++E K+ +   K+ + + +M + E K  ++EE + ++ E
Sbjct: 1590 QEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGE 1649

Query: 62   KMWEQEEKMWEQQR-LPEQKEKMWEQDERLREKEERMREQK--MWQQVEKMREKKKT--- 115
            K+ ++ EK+ ++++ L ++ EK+  ++E+L +K  ++ E K  + Q+VE++ ++++    
Sbjct: 1650 KLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDW 1709

Query: 116  -QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 174
             ++E  QE EE   + EE+ W++EE + ++E K+ E+++K+ E+EE +  Q EK+  +E 
Sbjct: 1710 QEKELAQELEELEWDMEELSWKEEE-LNQEEGKLVEEKKKLAEEEEALAWQREKLSEEET 1768

Query: 175  KMRDVE 180
            K+   E
Sbjct: 1769 KLAQEE 1774



 Score = 97.8 bits (242), Expect = 7e-21
 Identities = 47/180 (26%), Positives = 120/180 (66%), Gaps = 6/180 (3%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
            ++EE + +R +K+ +E E + ++ +K+ ++ EK+  +EEK+ ++  K+ E +  + ++ E
Sbjct: 1639 QKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVE 1698

Query: 62   KMWEQEEKM-WEQQRLPEQKEKM-WEQDE-RLREKEERMREQKMWQQVEKMREKKKT--- 115
            ++ ++E+ + W+++ L ++ E++ W+ +E   +E+E    E K+ ++ +K+ E+++    
Sbjct: 1699 ELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAW 1758

Query: 116  QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175
            Q EK+ E+E K+ ++EE++ +++EK+ + +EKM E+EE++  + E++ E++ K+  + E+
Sbjct: 1759 QREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRER 1818



 Score = 96.7 bits (239), Expect = 2e-20
 Identities = 52/193 (26%), Positives = 122/193 (63%), Gaps = 6/193 (3%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
            +EE ++ +   K+ +++  M + E K  ++EE + ++ EK+ ++ EK+ ++ +K+ ++ E
Sbjct: 1611 QEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWE 1670

Query: 62   KMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERM--REQKMWQQVEKMR---EKKKT 115
            K+  +EEK+ ++  +L E K  + ++ E L ++E+ +  +E+++ Q++E++    E+   
Sbjct: 1671 KVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSW 1730

Query: 116  QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175
            +EE++ ++E K+ E+++ + E+EE +  Q EK+ E+E K+ ++EE + +++EK+   +EK
Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEK 1790

Query: 176  MRDVEPAGGEAGE 188
            M + E   G   E
Sbjct: 1791 MPEEEERLGRKRE 1803



 Score = 94.0 bits (232), Expect = 1e-19
 Identities = 52/202 (25%), Positives = 118/202 (58%), Gaps = 15/202 (7%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
            +EE ++ E +KK+ EEEE +  Q EK+ E+E K+ ++EE + +++EK+ + +EKM E+EE
Sbjct: 1737 QEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEE 1796

Query: 62   KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT---QEE 118
            ++  + E++ E++    QK + W     +   EE  + + +  Q + + ++KK    ++E
Sbjct: 1797 RLGRKREQLIEKKMKLAQKRERW-----INSMEELTKNKMILYQKKNLAQEKKNLAQEKE 1851

Query: 119  KMQEQEEKMQEQEEMMWEQEEKMQEQEEKMW-------EQEEKMREQEEKMREQEEKMQG 171
            K+ +++E +   +E +   ++++ + + K+        + EEK+ +++E + +++EK+  
Sbjct: 1852 KLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAE 1911

Query: 172  QEEKMRDVEPAGGEAGEGSPQD 193
             E+K+  VE +  +  E   Q+
Sbjct: 1912 TEKKLVQVEDSLAKKQEKLAQE 1933



 Score = 92.4 bits (228), Expect = 3e-19
 Identities = 54/184 (29%), Positives = 108/184 (58%), Gaps = 16/184 (8%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
            REEE++ ++  K+ E + ++ ++ E++ ++E+ +       W+++E  QE EE  W+ EE
Sbjct: 1674 REEEKLAKKGGKLAEVKNILAQKVEELPQREQNLD------WQEKELAQELEELEWDMEE 1727

Query: 62   KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKM---REKKKTQ 116
              W++EE   E+ +L E+K+K+ E++E L  + E++ E+  K+ Q+ E +   +EK    
Sbjct: 1728 LSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQH 1787

Query: 117  EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEE-----KMREQEEKMREQEEKMQG 171
            +EKM E+EE++  + E + E++ K+ ++ E+     E     KM   ++K   QE+K   
Sbjct: 1788 KEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLA 1847

Query: 172  QEEK 175
            QE++
Sbjct: 1848 QEKE 1851



 Score = 91.7 bits (226), Expect = 5e-19
 Identities = 59/196 (30%), Positives = 111/196 (56%), Gaps = 23/196 (11%)

Query: 1    MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM--------WEQEEKMQEQ 52
            +++E ++ + +++M +EE  M E+ E+M   EEK+ +QE K+        W+  +K  ++
Sbjct: 1407 VQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDE 1466

Query: 53   EEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKM-----WQQVE 107
             +++  +  K W+  ++ WE +RL +++EK+ +  E+L  +EE ++E K      W+QV 
Sbjct: 1467 WKQVHGETRKSWKAWKEEWE-KRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVW 1525

Query: 108  KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQE--------QEEKMWEQEEKMREQE 159
            +     K++E++ +++EE   E EE+  E EEK Q+        QEE  W +  + R + 
Sbjct: 1526 ENMLSSKSKEQQYKDEEEVTLE-EEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARA 1584

Query: 160  EKMREQEEKMQGQEEK 175
            EK R QEE+   QEE+
Sbjct: 1585 EKKRAQEERKLAQEEE 1600



 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 54/192 (28%), Positives = 112/192 (58%), Gaps = 20/192 (10%)

Query: 6    RMRER-EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 64
            R R R EKK  +EE  + ++EEK+ ++E ++ ++E K+ +   K+ + + +M + E K  
Sbjct: 1579 RKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFA 1638

Query: 65   EQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERM--REQKMWQQVEKMREKKKTQEEKMQ 121
            ++EE + ++ ++L ++ EK+ ++ ++L +K E++   E+K+ ++  K+ E K    +K+ 
Sbjct: 1639 QKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKV- 1697

Query: 122  EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEE-------------KMREQEEKMREQEEK 168
              EE  Q ++ + W+++E  QE EE  W+ EE             K+ E+++K+ E+EE 
Sbjct: 1698 --EELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEA 1755

Query: 169  MQGQEEKMRDVE 180
            +  Q EK+ + E
Sbjct: 1756 LAWQREKLSEEE 1767



 Score = 90.1 bits (222), Expect = 1e-18
 Identities = 46/172 (26%), Positives = 103/172 (59%), Gaps = 8/172 (4%)

Query: 9    EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 68
            E EK++ +EEE + +  EK+  +EE ++E ++  WE+ +++ E       +E++  ++EE
Sbjct: 1484 EWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEE 1543

Query: 69   KMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR---EKKKTQEE-KMQEQE 124
               E++   E +EK    ++++ E++  ++E+  W ++ + R   EKK+ QEE K+ ++E
Sbjct: 1544 VTLEEEVSREGEEK----EQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEE 1599

Query: 125  EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
            EK+ ++E  + ++E K+ +   K+ + + +M + E K  ++EE +  + EK+
Sbjct: 1600 EKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKL 1651



 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 59/229 (25%), Positives = 123/229 (53%), Gaps = 54/229 (23%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
            + E+ +  +EK++ +E E +    E++  +EE++ ++E K+ E+++K+ E+EE +  Q E
Sbjct: 1702 QREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQRE 1761

Query: 62   KMWEQEEKM--------WEQQRLPEQKEKMWEQDERLREKEERMREQKM--------W-- 103
            K+ E+E K+         E+++L + KEKM E++ERL  K E++ E+KM        W  
Sbjct: 1762 KLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWIN 1821

Query: 104  --QQVEK----MREKKKTQEEK---MQEQEEKMQEQEEMMWEQ----------------- 137
              +++ K    + +KK   +EK    QE+E+  Q +E +++ +                 
Sbjct: 1822 SMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKL 1881

Query: 138  ----------EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
                      EEK+ +++E + +++EK+ E E+K+ + E+ +  ++EK+
Sbjct: 1882 GMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKL 1930



 Score = 85.1 bits (209), Expect = 5e-17
 Identities = 60/208 (28%), Positives = 114/208 (54%), Gaps = 36/208 (17%)

Query: 1    MREEERMREREKKM-REEEEMMREQEEKMQEQEEKMREQEEKMW---------------- 43
            + +EE+M E E K+ R+  E++ + EE+   +EE++    ++ W                
Sbjct: 2154 INKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKF 2213

Query: 44   -------EQEEKMQEQEEKMWEQEEKM-----WEQEEKMWEQQRLPEQKEKMWEQDERLR 91
                   E EE   E+ E + ++ EK       E+EE+  E++R   ++E++ E++E  +
Sbjct: 2214 SSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEER---EEEEVREEEEERK 2270

Query: 92   EKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKM----QEQEEK 147
            E+EE   +Q   ++ EK ++KK+ ++E++QE+EE  +E+EE+M E+E +     +E+EE 
Sbjct: 2271 EEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEES 2330

Query: 148  MWEQEEKMREQEEKMREQEEKMQGQEEK 175
               +EE  RE+E   +E++ K+Q Q  K
Sbjct: 2331 CSLEEEVDREKEILKKEKQFKLQEQRRK 2358



 Score = 83.2 bits (204), Expect = 2e-16
 Identities = 56/205 (27%), Positives = 115/205 (56%), Gaps = 8/205 (3%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKM-REQEEKMWEQEEKMQEQEEKMWEQE 60
            ++E+++  +++K+  +   M  +EEKM E+E K+ R+  E + + EE+   +EE++    
Sbjct: 2134 KDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFL 2193

Query: 61   EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
            ++ W + +   E +R  + KEK   Q + +  +E    E +      + +E   ++EE+ 
Sbjct: 2194 KRRWRKRK---EAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEE 2250

Query: 121  QEQEEKMQEQEEMMWEQEEKMQEQ--EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
            +E+EE+ +E+EE+  E+EE+ +E+  EEK  E+EE+ +++++K +++EE +Q +EE   +
Sbjct: 2251 REEEEE-REEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEE-VQEKEEVFEE 2308

Query: 179  VEPAGGEAGEGSPQDNPTAQEIMQL 203
             E    E    S  D    +E   L
Sbjct: 2309 KEEIMSEEETESLSDEEEEEESCSL 2333



 Score = 80.9 bits (198), Expect = 9e-16
 Identities = 44/193 (22%), Positives = 116/193 (60%), Gaps = 10/193 (5%)

Query: 1    MREEERMREREKKMR-EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
            + EEE    +E+++  +E+E + + +EKM E+EE++  + E++ E++ K+ ++ E+    
Sbjct: 1763 LSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINS 1822

Query: 60   EEK-------MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREK 112
             E+       +++++    E++ L ++KEK+ ++ E L   +ER+   K  +Q+ +++ K
Sbjct: 1823 MEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSK--KQLVQVKNK 1880

Query: 113  KKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 172
                 + + + EEK+ +++E + +++EK+ E E+K+ + E+ + +++EK+ +++ K+  +
Sbjct: 1881 LGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALE 1940

Query: 173  EEKMRDVEPAGGE 185
            +  ++  +   GE
Sbjct: 1941 KAMVQGKKRLRGE 1953



 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 48/194 (24%), Positives = 112/194 (57%), Gaps = 23/194 (11%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
            +EE +M + ++ +  +E  +  ++ K+  +E    E+  ++ + E+K+  ++ K+  +  
Sbjct: 2092 QEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMR 2151

Query: 62   KMWEQEEKMWEQQR----------LPEQKEKMWEQDERLREKEERMREQKMWQQVEKMRE 111
            +M  +EEKM E++           L +++E   E++E +   + R R++K  ++ +K +E
Sbjct: 2152 RMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKE 2211

Query: 112  KKKTQEEKMQEQE----------EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK 161
            K  +Q ++++ +E          +++++QE +  E+EE+ +E+EE+   +EE++RE+EE+
Sbjct: 2212 KFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEER---EEEEVREEEEE 2268

Query: 162  MREQEEKMQGQEEK 175
             +E+EE  + Q EK
Sbjct: 2269 RKEEEEGEEKQVEK 2282



 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 52/188 (27%), Positives = 99/188 (52%), Gaps = 14/188 (7%)

Query: 4    EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63
            +E  ++ EKK  ++     +Q  K  ++E K+ + + +M ++E  M E+ E+M   EEK+
Sbjct: 1385 KEISKKEEKKTFQKSP---KQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKV 1441

Query: 64   WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR-----EKKKTQEE 118
             +QE K+   +R P  ++     DE  +   E  +  K W++  + R     EK     E
Sbjct: 1442 VKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGE 1501

Query: 119  KMQEQEEKMQEQEEMMWEQEEKMQE------QEEKMWEQEEKMREQEEKMREQEEKMQGQ 172
            K+  +EE +QE +++ WE+ +++ E       +E+ ++ EE++  +EE  RE EEK Q  
Sbjct: 1502 KLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQV 1561

Query: 173  EEKMRDVE 180
             E+ R ++
Sbjct: 1562 TEEQRHIQ 1569



 Score = 75.9 bits (185), Expect = 3e-14
 Identities = 50/153 (32%), Positives = 93/153 (60%), Gaps = 13/153 (8%)

Query: 9    EREKKMREEEEMMREQEEKMQ----EQEEKMREQEEKMWEQEEKMQEQEEKMWEQ--EEK 62
            E E+   EE E + ++ EK +    E+EE+  E+EE+  E+EE  +E+EE+  E+  EEK
Sbjct: 2221 ESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEER--EEEEVREEEEERKEEEEGEEK 2278

Query: 63   MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQE 122
              E+EE+  ++++  ++KE++ E++E   EKEE M E    ++ E + ++++ +EE    
Sbjct: 2279 QVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE----EETESLSDEEE-EEESCSL 2333

Query: 123  QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM 155
            +EE  +E+E +  E++ K+QEQ  K     E++
Sbjct: 2334 EEEVDREKEILKKEKQFKLQEQRRKSLRGRERV 2366



 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 40/173 (23%), Positives = 99/173 (57%), Gaps = 10/173 (5%)

Query: 4    EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63
            +ER+   +K++ + +  +    + + + EEK+ +++E + +++EK+ E E+K+ + E+ +
Sbjct: 1864 KERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSL 1923

Query: 64   WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ-- 121
             +++EK+ +++     ++ M +  +RLR + +  +E+K         E K+  EEKM+  
Sbjct: 1924 AKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALN-----LEMKRLAEEKMRLV 1978

Query: 122  EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 174
            E +E + + E     ++ KM + E++++E++  +   EEK+   E+++   EE
Sbjct: 1979 EGKETLSKGETPETSRQRKMTQVEQELFERKLSL---EEKILLHEDRILAMEE 2028



 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 42/207 (20%), Positives = 102/207 (49%), Gaps = 28/207 (13%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ----EEKMW 57
            +EE+ +    K++ EE+  + E +E + + E     ++ KM + E+++ E+    EEK+ 
Sbjct: 1958 KEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKIL 2017

Query: 58   EQEEKMWEQEEKMWEQQRLP-EQKEKMWEQDER---------LREKEERMREQKMWQQVE 107
              E+++   EE    + +L   + ++++ Q +R         ++++E   +E     ++ 
Sbjct: 2018 LHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKIL 2077

Query: 108  KMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKM----WE----------QEE 153
            K  +K    E K+ ++E KM + +  ++ +E ++  ++ K+    W+           E+
Sbjct: 2078 KALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEK 2137

Query: 154  KMREQEEKMREQEEKMQGQEEKMRDVE 180
            K+  ++ K+  +  +M  +EEKM + E
Sbjct: 2138 KLARKQRKLANKMRRMINKEEKMTEEE 2164



 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 38/185 (20%), Positives = 103/185 (55%), Gaps = 16/185 (8%)

Query: 11   EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ------EEKMWEQEEKMW 64
            E+K+ +E+E + +++EK+ E E+K+ + E+ + +++EK+ ++      E+ M + ++++ 
Sbjct: 1892 EEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLR 1951

Query: 65   EQEEKMWEQQRLPEQKEKMWEQDERLREKEERM---------REQKMWQQVEKMREKKKT 115
             + +   E++ L  + +++ E+  RL E +E +         R++KM Q  +++ E+K +
Sbjct: 1952 GELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLS 2011

Query: 116  QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQ-EEKMREQEEKMREQEEKMQGQEE 174
             EEK+   E+++   EE    + +    + ++++ Q + K+ +   K+ ++ E +  +  
Sbjct: 2012 LEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPA 2071

Query: 175  KMRDV 179
            K+  +
Sbjct: 2072 KLNKI 2076



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 46/199 (23%), Positives = 89/199 (44%), Gaps = 55/199 (27%)

Query: 24   QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKM 83
            +E+ +Q   +++   +E M  +EE+ Q++   M   EE           Q  L + K+ +
Sbjct: 1325 REDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEET----------QVILKKGKKVI 1374

Query: 84   WEQD------ERLREKEERMREQKMWQQ----VEKMREKKKTQEEKMQEQEEKMQEQEEM 133
            + +       + + +KEE+   QK  +Q    V+K R+  K + E M ++E  M E+ E 
Sbjct: 1375 FLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKRE-MTKEERDMSEEVEE 1433

Query: 134  MWEQEEKMQEQEEKM------------------WEQ----------------EEKMREQE 159
            M   EEK+ +QE K+                  W+Q                E+++ ++E
Sbjct: 1434 MATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEE 1493

Query: 160  EKMREQEEKMQGQEEKMRD 178
            EK+ +  EK+  +EE +++
Sbjct: 1494 EKLHQAGEKLSPEEEMLQE 1512


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
           sapiens]
          Length = 1293

 Score = 94.7 bits (234), Expect = 6e-20
 Identities = 56/174 (32%), Positives = 102/174 (58%), Gaps = 14/174 (8%)

Query: 4   EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63
           E+  RE E + + EEE  + QEE  ++QEE +R Q+E   E+ ++ +E+E    +QEE +
Sbjct: 732 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKRREEEELARRKQEEAL 788

Query: 64  WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
             Q E+    +R  E++E+  +Q+E LR  EER RE+          E+++ QEE +++Q
Sbjct: 789 RRQREQEIALRRQREEEERQ-QQEEALRRLEERRREE----------EERRKQEELLRKQ 837

Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
           EE+  +      E + +++E   +M E+  ++R +EE+ + +E ++Q Q+E MR
Sbjct: 838 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 891



 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 67/210 (31%), Positives = 121/210 (57%), Gaps = 38/210 (18%)

Query: 2   REEERMRERE-----KKMREEEEMMREQ--EEKMQEQEEKMREQEEKMWEQEEKMQEQEE 54
           REEE +  R+     ++ RE+E  +R Q  EE+ Q+QEE +R  EE+  E+EE+ ++QEE
Sbjct: 774 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQEE 832

Query: 55  KMWEQEEK--MWEQEEKMWEQQRLPEQKEKMWEQDERLR--EKEERMREQKMWQQVEKMR 110
            + +QEE+   W +EE+   Q+RL E + +M E+  RLR  E+E + +E ++ +Q E MR
Sbjct: 833 LLRKQEEEAAKWAREEEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 891

Query: 111 EKKKTQEEKMQEQEEKMQEQEEMM-------WEQE-----------------EKMQEQEE 146
           ++++ QE   + Q+++ Q+Q   M       W Q+                 +K++E+ E
Sbjct: 892 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 951

Query: 147 KMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
           +   +EE+ R+Q E M+  +++ Q Q++K+
Sbjct: 952 RQL-REEQRRQQRELMKALQQQQQQQQQKL 980



 Score = 74.3 bits (181), Expect = 8e-14
 Identities = 53/165 (32%), Positives = 96/165 (58%), Gaps = 16/165 (9%)

Query: 18  EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 77
           E++ + ++ K  + E++ RE E +   +EE+ + QEE   +QEE +  Q+E+  E++R  
Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE--ERKRRE 775

Query: 78  EQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQ 137
           E++    +Q+E LR    R REQ++  + ++  E+++ QEE ++  EE+ +E+EE   +Q
Sbjct: 776 EEELARRKQEEALR----RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR-KQ 830

Query: 138 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPA 182
           EE +++QEE   E  +  RE+EE  R  EE       ++R  E A
Sbjct: 831 EELLRKQEE---EAAKWAREEEEAQRRLEEN------RLRMEEEA 866



 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 44/195 (22%), Positives = 104/195 (53%), Gaps = 22/195 (11%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
            REEE  R++E+ +R++EE   +   + +E + ++ E   +M E+  +++ +EE+   +E 
Sbjct: 822  REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 881

Query: 62   KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEKMR 110
            ++  Q+E M ++Q+  E   ++ +Q ++ +  + ++     W           Q    + 
Sbjct: 882  EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 941

Query: 111  EKKKTQEEK-MQEQEEKMQEQEEMMWEQEEKMQEQEEKM--WEQEEK--------MREQE 159
            E +K +EE+  Q +EE+ ++Q E+M   +++ Q+Q++K+  W    K        +  Q+
Sbjct: 942  EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1001

Query: 160  EKMREQEEKMQGQEE 174
            E+ R+ +++ Q Q++
Sbjct: 1002 EEARQMQKQQQQQQQ 1016



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 38/159 (23%), Positives = 81/159 (50%), Gaps = 25/159 (15%)

Query: 6    RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE----QEEKMQEQEEKMWEQEE 61
            RM E   ++R EEE  + +E ++Q Q+E MR+++++       Q+++ Q+Q  +M     
Sbjct: 861  RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 920

Query: 62   KMWEQEE-----------KMWEQQRLPEQKEKMWEQDERLREKE--------ERMREQKM 102
              W Q+             + E Q+L E++E+   +++R +++E        ++ ++QK+
Sbjct: 921  STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 980

Query: 103  --WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE 139
              W  V K     K+  E  QE+  +MQ+Q++   + ++
Sbjct: 981  SGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1019



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 41/193 (21%), Positives = 94/193 (48%), Gaps = 27/193 (13%)

Query: 9   EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM---QEQEEKMWEQEEKMWE 65
           ++E+  R++E     Q + +Q Q+  +++Q  ++  Q++K     +Q++++    ++   
Sbjct: 600 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 659

Query: 66  QEEKMWEQQRLPEQKEKMWEQDE-RLREKEERMREQKMWQ----------------QVEK 108
            + ++ +Q  +P     +   D   + E +    +  +W+                 +E+
Sbjct: 660 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 719

Query: 109 MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR---EQEEKMREQ 165
           +++ +K +  K+   E++ +E E     +EE+ + QEE   +QEE +R   E+E K RE+
Sbjct: 720 LQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 776

Query: 166 EE-KMQGQEEKMR 177
           EE   + QEE +R
Sbjct: 777 EELARRKQEEALR 789



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 20/76 (26%), Positives = 44/76 (57%), Gaps = 4/76 (5%)

Query: 9    EREKKMREEEEMMREQEEKMQEQEEKMREQEEKM--WEQEEKMQEQEEKMWEQEEKMWEQ 66
            ERE+++REE+   R+Q E M+  +++ ++Q++K+  W    K     + + E +++   Q
Sbjct: 949  ERERQLREEQR--RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1006

Query: 67   EEKMWEQQRLPEQKEK 82
             +K  +QQ+  +Q  +
Sbjct: 1007 MQKQQQQQQQHQQPNR 1022



 Score = 33.5 bits (75), Expect = 0.17
 Identities = 15/85 (17%), Positives = 45/85 (52%)

Query: 14   MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 73
            + E +++  E+E +++E++ + + +  K  +Q+++ Q+Q+   W    K     + + E 
Sbjct: 940  LAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEI 999

Query: 74   QRLPEQKEKMWEQDERLREKEERMR 98
            Q+   ++ +  +Q ++  ++  R R
Sbjct: 1000 QQEEARQMQKQQQQQQQHQQPNRAR 1024



 Score = 32.7 bits (73), Expect = 0.28
 Identities = 44/227 (19%), Positives = 92/227 (40%), Gaps = 35/227 (15%)

Query: 3   EEERMREREKKMREEEEMMREQE---EKMQEQEEKMREQEEKMWE--QEEKMQEQEEKMW 57
           EE   R  EK  R++      +E     +  + E +R + E  W   +EE+  E E+  W
Sbjct: 162 EERGDRRFEKPGRKDVGRPNFEEGGPTSVGRKHEFIRSESEN-WRIFREEQNGEDEDGGW 220

Query: 58  E-----QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQ-QVEKMRE 111
                 ++ + W      W +     ++ + +E D R R+ E   R  +     ++  R+
Sbjct: 221 RLAGSRRDGERWRPHSPGWREHM---ERRRRFEFDFRDRDDERGYRRVRSGSGSIDDDRD 277

Query: 112 KK-----KTQEEKM-------------QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEE 153
                  +  EE+M             + Q+E + E++EM +   ++ +E  +      E
Sbjct: 278 SLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEECSDSEGSHNE 337

Query: 154 KMREQEEKMREQEEKMQ--GQEEKMRDVEPAGGEAGEGSPQDNPTAQ 198
           + +E ++  +++ EK    G E      + +   A  G+P D+ + +
Sbjct: 338 EAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQE 384



 Score = 28.1 bits (61), Expect = 7.0
 Identities = 18/103 (17%), Positives = 50/103 (48%), Gaps = 9/103 (8%)

Query: 16   EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 75
            E  + +R       E +E  ++  E+  +Q+   Q Q++++ +Q+     Q++   +  +
Sbjct: 1163 EVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQ-----QQQPPQQPPQ 1217

Query: 76   LPEQKEKMWEQD----ERLREKEERMREQKMWQQVEKMREKKK 114
             P+Q++ +W  +      + +  +   +Q  ++ V+  ++KKK
Sbjct: 1218 QPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKK 1260



 Score = 27.7 bits (60), Expect = 9.1
 Identities = 16/89 (17%), Positives = 41/89 (46%), Gaps = 12/89 (13%)

Query: 104  QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE----------QEE 153
            +Q  + R K+K  +++ Q+Q  + Q+Q+    +Q  +  +Q++ +W           Q  
Sbjct: 1183 KQFLERRAKQKANQQRQQQQLPQQQQQQPP--QQPPQQPQQQDSVWGMNHSTLHSVFQTN 1240

Query: 154  KMREQEEKMREQEEKMQGQEEKMRDVEPA 182
            +   Q+      +   + +++KM   +P+
Sbjct: 1241 QSNNQQSNFEAVQSGKKKKKQKMVRADPS 1269


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
           sapiens]
          Length = 1320

 Score = 94.7 bits (234), Expect = 6e-20
 Identities = 56/174 (32%), Positives = 102/174 (58%), Gaps = 14/174 (8%)

Query: 4   EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63
           E+  RE E + + EEE  + QEE  ++QEE +R Q+E   E+ ++ +E+E    +QEE +
Sbjct: 759 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKRREEEELARRKQEEAL 815

Query: 64  WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
             Q E+    +R  E++E+  +Q+E LR  EER RE+          E+++ QEE +++Q
Sbjct: 816 RRQREQEIALRRQREEEERQ-QQEEALRRLEERRREE----------EERRKQEELLRKQ 864

Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
           EE+  +      E + +++E   +M E+  ++R +EE+ + +E ++Q Q+E MR
Sbjct: 865 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 918



 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 67/210 (31%), Positives = 121/210 (57%), Gaps = 38/210 (18%)

Query: 2    REEERMRERE-----KKMREEEEMMREQ--EEKMQEQEEKMREQEEKMWEQEEKMQEQEE 54
            REEE +  R+     ++ RE+E  +R Q  EE+ Q+QEE +R  EE+  E+EE+ ++QEE
Sbjct: 801  REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQEE 859

Query: 55   KMWEQEEK--MWEQEEKMWEQQRLPEQKEKMWEQDERLR--EKEERMREQKMWQQVEKMR 110
             + +QEE+   W +EE+   Q+RL E + +M E+  RLR  E+E + +E ++ +Q E MR
Sbjct: 860  LLRKQEEEAAKWAREEEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 918

Query: 111  EKKKTQEEKMQEQEEKMQEQEEMM-------WEQE-----------------EKMQEQEE 146
            ++++ QE   + Q+++ Q+Q   M       W Q+                 +K++E+ E
Sbjct: 919  QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 978

Query: 147  KMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
            +   +EE+ R+Q E M+  +++ Q Q++K+
Sbjct: 979  RQL-REEQRRQQRELMKALQQQQQQQQQKL 1007



 Score = 74.3 bits (181), Expect = 8e-14
 Identities = 53/165 (32%), Positives = 96/165 (58%), Gaps = 16/165 (9%)

Query: 18  EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 77
           E++ + ++ K  + E++ RE E +   +EE+ + QEE   +QEE +  Q+E+  E++R  
Sbjct: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE--ERKRRE 802

Query: 78  EQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQ 137
           E++    +Q+E LR    R REQ++  + ++  E+++ QEE ++  EE+ +E+EE   +Q
Sbjct: 803 EEELARRKQEEALR----RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR-KQ 857

Query: 138 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPA 182
           EE +++QEE   E  +  RE+EE  R  EE       ++R  E A
Sbjct: 858 EELLRKQEE---EAAKWAREEEEAQRRLEEN------RLRMEEEA 893



 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 44/195 (22%), Positives = 104/195 (53%), Gaps = 22/195 (11%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
            REEE  R++E+ +R++EE   +   + +E + ++ E   +M E+  +++ +EE+   +E 
Sbjct: 849  REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 908

Query: 62   KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEKMR 110
            ++  Q+E M ++Q+  E   ++ +Q ++ +  + ++     W           Q    + 
Sbjct: 909  EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 968

Query: 111  EKKKTQEEK-MQEQEEKMQEQEEMMWEQEEKMQEQEEKM--WEQEEK--------MREQE 159
            E +K +EE+  Q +EE+ ++Q E+M   +++ Q+Q++K+  W    K        +  Q+
Sbjct: 969  EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1028

Query: 160  EKMREQEEKMQGQEE 174
            E+ R+ +++ Q Q++
Sbjct: 1029 EEARQMQKQQQQQQQ 1043



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 38/159 (23%), Positives = 81/159 (50%), Gaps = 25/159 (15%)

Query: 6    RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE----QEEKMQEQEEKMWEQEE 61
            RM E   ++R EEE  + +E ++Q Q+E MR+++++       Q+++ Q+Q  +M     
Sbjct: 888  RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 947

Query: 62   KMWEQEE-----------KMWEQQRLPEQKEKMWEQDERLREKE--------ERMREQKM 102
              W Q+             + E Q+L E++E+   +++R +++E        ++ ++QK+
Sbjct: 948  STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 1007

Query: 103  --WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE 139
              W  V K     K+  E  QE+  +MQ+Q++   + ++
Sbjct: 1008 SGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1046



 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 48/206 (23%), Positives = 102/206 (49%), Gaps = 52/206 (25%)

Query: 2    REEERMREREKKM----REEEEMMREQEE---KMQEQEEKMREQEEKMWEQEEKMQEQEE 54
            ++EE +R++E++     REEEE  R  EE   +M+E+  ++R +EE+   +E ++Q Q+E
Sbjct: 856  KQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 915

Query: 55   KMWEQEEKM-------WEQEEKMWEQQRLPEQK----------------------EKMWE 85
             M +++++         +Q+++   Q +LP                         +K+ E
Sbjct: 916  LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 975

Query: 86   QDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQE 145
            + ER + +EE+ R+Q         RE  K  +++ Q+Q++K+       W    K     
Sbjct: 976  ERER-QLREEQRRQQ---------RELMKALQQQQQQQQQKLSG-----WGNVSKPSGTT 1020

Query: 146  EKMWE-QEEKMREQEEKMREQEEKMQ 170
            + + E Q+E+ R+ +++ ++Q++  Q
Sbjct: 1021 KSLLEIQQEEARQMQKQQQQQQQHQQ 1046



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 41/193 (21%), Positives = 94/193 (48%), Gaps = 27/193 (13%)

Query: 9   EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM---QEQEEKMWEQEEKMWE 65
           ++E+  R++E     Q + +Q Q+  +++Q  ++  Q++K     +Q++++    ++   
Sbjct: 627 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 686

Query: 66  QEEKMWEQQRLPEQKEKMWEQDE-RLREKEERMREQKMWQ----------------QVEK 108
            + ++ +Q  +P     +   D   + E +    +  +W+                 +E+
Sbjct: 687 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 746

Query: 109 MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR---EQEEKMREQ 165
           +++ +K +  K+   E++ +E E     +EE+ + QEE   +QEE +R   E+E K RE+
Sbjct: 747 LQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 803

Query: 166 EE-KMQGQEEKMR 177
           EE   + QEE +R
Sbjct: 804 EELARRKQEEALR 816



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 20/76 (26%), Positives = 44/76 (57%), Gaps = 4/76 (5%)

Query: 9    EREKKMREEEEMMREQEEKMQEQEEKMREQEEKM--WEQEEKMQEQEEKMWEQEEKMWEQ 66
            ERE+++REE+   R+Q E M+  +++ ++Q++K+  W    K     + + E +++   Q
Sbjct: 976  ERERQLREEQR--RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1033

Query: 67   EEKMWEQQRLPEQKEK 82
             +K  +QQ+  +Q  +
Sbjct: 1034 MQKQQQQQQQHQQPNR 1049



 Score = 33.5 bits (75), Expect = 0.17
 Identities = 15/85 (17%), Positives = 45/85 (52%)

Query: 14   MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 73
            + E +++  E+E +++E++ + + +  K  +Q+++ Q+Q+   W    K     + + E 
Sbjct: 967  LAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEI 1026

Query: 74   QRLPEQKEKMWEQDERLREKEERMR 98
            Q+   ++ +  +Q ++  ++  R R
Sbjct: 1027 QQEEARQMQKQQQQQQQHQQPNRAR 1051



 Score = 28.1 bits (61), Expect = 7.0
 Identities = 18/103 (17%), Positives = 50/103 (48%), Gaps = 9/103 (8%)

Query: 16   EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 75
            E  + +R       E +E  ++  E+  +Q+   Q Q++++ +Q+     Q++   +  +
Sbjct: 1190 EVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQ-----QQQPPQQPPQ 1244

Query: 76   LPEQKEKMWEQD----ERLREKEERMREQKMWQQVEKMREKKK 114
             P+Q++ +W  +      + +  +   +Q  ++ V+  ++KKK
Sbjct: 1245 QPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKK 1287



 Score = 27.7 bits (60), Expect = 9.1
 Identities = 16/89 (17%), Positives = 41/89 (46%), Gaps = 12/89 (13%)

Query: 104  QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE----------QEE 153
            +Q  + R K+K  +++ Q+Q  + Q+Q+    +Q  +  +Q++ +W           Q  
Sbjct: 1210 KQFLERRAKQKANQQRQQQQLPQQQQQQPP--QQPPQQPQQQDSVWGMNHSTLHSVFQTN 1267

Query: 154  KMREQEEKMREQEEKMQGQEEKMRDVEPA 182
            +   Q+      +   + +++KM   +P+
Sbjct: 1268 QSNNQQSNFEAVQSGKKKKKQKMVRADPS 1296


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 94.7 bits (234), Expect = 6e-20
 Identities = 56/174 (32%), Positives = 102/174 (58%), Gaps = 14/174 (8%)

Query: 4   EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63
           E+  RE E + + EEE  + QEE  ++QEE +R Q+E   E+ ++ +E+E    +QEE +
Sbjct: 738 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKRREEEELARRKQEEAL 794

Query: 64  WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
             Q E+    +R  E++E+  +Q+E LR  EER RE+          E+++ QEE +++Q
Sbjct: 795 RRQREQEIALRRQREEEERQ-QQEEALRRLEERRREE----------EERRKQEELLRKQ 843

Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
           EE+  +      E + +++E   +M E+  ++R +EE+ + +E ++Q Q+E MR
Sbjct: 844 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897



 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 67/210 (31%), Positives = 121/210 (57%), Gaps = 38/210 (18%)

Query: 2   REEERMRERE-----KKMREEEEMMREQ--EEKMQEQEEKMREQEEKMWEQEEKMQEQEE 54
           REEE +  R+     ++ RE+E  +R Q  EE+ Q+QEE +R  EE+  E+EE+ ++QEE
Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQEE 838

Query: 55  KMWEQEEK--MWEQEEKMWEQQRLPEQKEKMWEQDERLR--EKEERMREQKMWQQVEKMR 110
            + +QEE+   W +EE+   Q+RL E + +M E+  RLR  E+E + +E ++ +Q E MR
Sbjct: 839 LLRKQEEEAAKWAREEEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897

Query: 111 EKKKTQEEKMQEQEEKMQEQEEMM-------WEQE-----------------EKMQEQEE 146
           ++++ QE   + Q+++ Q+Q   M       W Q+                 +K++E+ E
Sbjct: 898 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 957

Query: 147 KMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
           +   +EE+ R+Q E M+  +++ Q Q++K+
Sbjct: 958 RQL-REEQRRQQRELMKALQQQQQQQQQKL 986



 Score = 74.3 bits (181), Expect = 8e-14
 Identities = 53/165 (32%), Positives = 96/165 (58%), Gaps = 16/165 (9%)

Query: 18  EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 77
           E++ + ++ K  + E++ RE E +   +EE+ + QEE   +QEE +  Q+E+  E++R  
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE--ERKRRE 781

Query: 78  EQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQ 137
           E++    +Q+E LR    R REQ++  + ++  E+++ QEE ++  EE+ +E+EE   +Q
Sbjct: 782 EEELARRKQEEALR----RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR-KQ 836

Query: 138 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPA 182
           EE +++QEE   E  +  RE+EE  R  EE       ++R  E A
Sbjct: 837 EELLRKQEE---EAAKWAREEEEAQRRLEEN------RLRMEEEA 872



 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 44/195 (22%), Positives = 104/195 (53%), Gaps = 22/195 (11%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
            REEE  R++E+ +R++EE   +   + +E + ++ E   +M E+  +++ +EE+   +E 
Sbjct: 828  REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887

Query: 62   KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEKMR 110
            ++  Q+E M ++Q+  E   ++ +Q ++ +  + ++     W           Q    + 
Sbjct: 888  EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 947

Query: 111  EKKKTQEEK-MQEQEEKMQEQEEMMWEQEEKMQEQEEKM--WEQEEK--------MREQE 159
            E +K +EE+  Q +EE+ ++Q E+M   +++ Q+Q++K+  W    K        +  Q+
Sbjct: 948  EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1007

Query: 160  EKMREQEEKMQGQEE 174
            E+ R+ +++ Q Q++
Sbjct: 1008 EEARQMQKQQQQQQQ 1022



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 38/159 (23%), Positives = 81/159 (50%), Gaps = 25/159 (15%)

Query: 6    RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE----QEEKMQEQEEKMWEQEE 61
            RM E   ++R EEE  + +E ++Q Q+E MR+++++       Q+++ Q+Q  +M     
Sbjct: 867  RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 926

Query: 62   KMWEQEE-----------KMWEQQRLPEQKEKMWEQDERLREKE--------ERMREQKM 102
              W Q+             + E Q+L E++E+   +++R +++E        ++ ++QK+
Sbjct: 927  STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 986

Query: 103  --WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE 139
              W  V K     K+  E  QE+  +MQ+Q++   + ++
Sbjct: 987  SGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1025



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 41/193 (21%), Positives = 94/193 (48%), Gaps = 27/193 (13%)

Query: 9   EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM---QEQEEKMWEQEEKMWE 65
           ++E+  R++E     Q + +Q Q+  +++Q  ++  Q++K     +Q++++    ++   
Sbjct: 606 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665

Query: 66  QEEKMWEQQRLPEQKEKMWEQDE-RLREKEERMREQKMWQ----------------QVEK 108
            + ++ +Q  +P     +   D   + E +    +  +W+                 +E+
Sbjct: 666 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 725

Query: 109 MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR---EQEEKMREQ 165
           +++ +K +  K+   E++ +E E     +EE+ + QEE   +QEE +R   E+E K RE+
Sbjct: 726 LQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 782

Query: 166 EE-KMQGQEEKMR 177
           EE   + QEE +R
Sbjct: 783 EELARRKQEEALR 795



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 20/76 (26%), Positives = 44/76 (57%), Gaps = 4/76 (5%)

Query: 9    EREKKMREEEEMMREQEEKMQEQEEKMREQEEKM--WEQEEKMQEQEEKMWEQEEKMWEQ 66
            ERE+++REE+   R+Q E M+  +++ ++Q++K+  W    K     + + E +++   Q
Sbjct: 955  ERERQLREEQR--RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1012

Query: 67   EEKMWEQQRLPEQKEK 82
             +K  +QQ+  +Q  +
Sbjct: 1013 MQKQQQQQQQHQQPNR 1028



 Score = 33.5 bits (75), Expect = 0.17
 Identities = 15/85 (17%), Positives = 45/85 (52%)

Query: 14   MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 73
            + E +++  E+E +++E++ + + +  K  +Q+++ Q+Q+   W    K     + + E 
Sbjct: 946  LAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEI 1005

Query: 74   QRLPEQKEKMWEQDERLREKEERMR 98
            Q+   ++ +  +Q ++  ++  R R
Sbjct: 1006 QQEEARQMQKQQQQQQQHQQPNRAR 1030



 Score = 29.3 bits (64), Expect = 3.1
 Identities = 16/78 (20%), Positives = 38/78 (48%), Gaps = 2/78 (2%)

Query: 123 QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ--GQEEKMRDVE 180
           Q+E + E++EM +   ++ +E  +      E+ +E ++  +++ EK    G E      +
Sbjct: 313 QKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQ 372

Query: 181 PAGGEAGEGSPQDNPTAQ 198
            +   A  G+P D+ + +
Sbjct: 373 TSSSSARPGTPSDHQSQE 390



 Score = 28.1 bits (61), Expect = 7.0
 Identities = 18/103 (17%), Positives = 50/103 (48%), Gaps = 9/103 (8%)

Query: 16   EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 75
            E  + +R       E +E  ++  E+  +Q+   Q Q++++ +Q+     Q++   +  +
Sbjct: 1169 EVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQ-----QQQPPQQPPQ 1223

Query: 76   LPEQKEKMWEQD----ERLREKEERMREQKMWQQVEKMREKKK 114
             P+Q++ +W  +      + +  +   +Q  ++ V+  ++KKK
Sbjct: 1224 QPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKK 1266



 Score = 27.7 bits (60), Expect = 9.1
 Identities = 16/89 (17%), Positives = 41/89 (46%), Gaps = 12/89 (13%)

Query: 104  QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE----------QEE 153
            +Q  + R K+K  +++ Q+Q  + Q+Q+    +Q  +  +Q++ +W           Q  
Sbjct: 1189 KQFLERRAKQKANQQRQQQQLPQQQQQQPP--QQPPQQPQQQDSVWGMNHSTLHSVFQTN 1246

Query: 154  KMREQEEKMREQEEKMQGQEEKMRDVEPA 182
            +   Q+      +   + +++KM   +P+
Sbjct: 1247 QSNNQQSNFEAVQSGKKKKKQKMVRADPS 1275


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 94.7 bits (234), Expect = 6e-20
 Identities = 56/174 (32%), Positives = 102/174 (58%), Gaps = 14/174 (8%)

Query: 4   EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63
           E+  RE E + + EEE  + QEE  ++QEE +R Q+E   E+ ++ +E+E    +QEE +
Sbjct: 738 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE---EERKRREEEELARRKQEEAL 794

Query: 64  WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
             Q E+    +R  E++E+  +Q+E LR  EER RE+          E+++ QEE +++Q
Sbjct: 795 RRQREQEIALRRQREEEERQ-QQEEALRRLEERRREE----------EERRKQEELLRKQ 843

Query: 124 EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
           EE+  +      E + +++E   +M E+  ++R +EE+ + +E ++Q Q+E MR
Sbjct: 844 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897



 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 67/210 (31%), Positives = 121/210 (57%), Gaps = 38/210 (18%)

Query: 2   REEERMRERE-----KKMREEEEMMREQ--EEKMQEQEEKMREQEEKMWEQEEKMQEQEE 54
           REEE +  R+     ++ RE+E  +R Q  EE+ Q+QEE +R  EE+  E+EE+ ++QEE
Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER-RKQEE 838

Query: 55  KMWEQEEK--MWEQEEKMWEQQRLPEQKEKMWEQDERLR--EKEERMREQKMWQQVEKMR 110
            + +QEE+   W +EE+   Q+RL E + +M E+  RLR  E+E + +E ++ +Q E MR
Sbjct: 839 LLRKQEEEAAKWAREEEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 897

Query: 111 EKKKTQEEKMQEQEEKMQEQEEMM-------WEQE-----------------EKMQEQEE 146
           ++++ QE   + Q+++ Q+Q   M       W Q+                 +K++E+ E
Sbjct: 898 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 957

Query: 147 KMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
           +   +EE+ R+Q E M+  +++ Q Q++K+
Sbjct: 958 RQL-REEQRRQQRELMKALQQQQQQQQQKL 986



 Score = 74.3 bits (181), Expect = 8e-14
 Identities = 53/165 (32%), Positives = 96/165 (58%), Gaps = 16/165 (9%)

Query: 18  EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 77
           E++ + ++ K  + E++ RE E +   +EE+ + QEE   +QEE +  Q+E+  E++R  
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE--ERKRRE 781

Query: 78  EQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQ 137
           E++    +Q+E LR    R REQ++  + ++  E+++ QEE ++  EE+ +E+EE   +Q
Sbjct: 782 EEELARRKQEEALR----RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR-KQ 836

Query: 138 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPA 182
           EE +++QEE   E  +  RE+EE  R  EE       ++R  E A
Sbjct: 837 EELLRKQEE---EAAKWAREEEEAQRRLEEN------RLRMEEEA 872



 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 44/195 (22%), Positives = 104/195 (53%), Gaps = 22/195 (11%)

Query: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
            REEE  R++E+ +R++EE   +   + +E + ++ E   +M E+  +++ +EE+   +E 
Sbjct: 828  REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887

Query: 62   KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW-----------QQVEKMR 110
            ++  Q+E M ++Q+  E   ++ +Q ++ +  + ++     W           Q    + 
Sbjct: 888  EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLA 947

Query: 111  EKKKTQEEK-MQEQEEKMQEQEEMMWEQEEKMQEQEEKM--WEQEEK--------MREQE 159
            E +K +EE+  Q +EE+ ++Q E+M   +++ Q+Q++K+  W    K        +  Q+
Sbjct: 948  EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1007

Query: 160  EKMREQEEKMQGQEE 174
            E+ R+ +++ Q Q++
Sbjct: 1008 EEARQMQKQQQQQQQ 1022



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 38/159 (23%), Positives = 81/159 (50%), Gaps = 25/159 (15%)

Query: 6    RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE----QEEKMQEQEEKMWEQEE 61
            RM E   ++R EEE  + +E ++Q Q+E MR+++++       Q+++ Q+Q  +M     
Sbjct: 867  RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 926

Query: 62   KMWEQEE-----------KMWEQQRLPEQKEKMWEQDERLREKE--------ERMREQKM 102
              W Q+             + E Q+L E++E+   +++R +++E        ++ ++QK+
Sbjct: 927  STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 986

Query: 103  --WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEE 139
              W  V K     K+  E  QE+  +MQ+Q++   + ++
Sbjct: 987  SGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1025



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 41/193 (21%), Positives = 94/193 (48%), Gaps = 27/193 (13%)

Query: 9   EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKM---QEQEEKMWEQEEKMWE 65
           ++E+  R++E     Q + +Q Q+  +++Q  ++  Q++K     +Q++++    ++   
Sbjct: 606 DQERLTRQQELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQT 665

Query: 66  QEEKMWEQQRLPEQKEKMWEQDE-RLREKEERMREQKMWQ----------------QVEK 108
            + ++ +Q  +P     +   D   + E +    +  +W+                 +E+
Sbjct: 666 LKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQ 725

Query: 109 MREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR---EQEEKMREQ 165
           +++ +K +  K+   E++ +E E     +EE+ + QEE   +QEE +R   E+E K RE+
Sbjct: 726 LQQLEKAKAAKL---EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 782

Query: 166 EE-KMQGQEEKMR 177
           EE   + QEE +R
Sbjct: 783 EELARRKQEEALR 795



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 20/76 (26%), Positives = 44/76 (57%), Gaps = 4/76 (5%)

Query: 9    EREKKMREEEEMMREQEEKMQEQEEKMREQEEKM--WEQEEKMQEQEEKMWEQEEKMWEQ 66
            ERE+++REE+   R+Q E M+  +++ ++Q++K+  W    K     + + E +++   Q
Sbjct: 955  ERERQLREEQR--RQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQ 1012

Query: 67   EEKMWEQQRLPEQKEK 82
             +K  +QQ+  +Q  +
Sbjct: 1013 MQKQQQQQQQHQQPNR 1028



 Score = 33.5 bits (75), Expect = 0.17
 Identities = 15/85 (17%), Positives = 45/85 (52%)

Query: 14   MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 73
            + E +++  E+E +++E++ + + +  K  +Q+++ Q+Q+   W    K     + + E 
Sbjct: 946  LAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEI 1005

Query: 74   QRLPEQKEKMWEQDERLREKEERMR 98
            Q+   ++ +  +Q ++  ++  R R
Sbjct: 1006 QQEEARQMQKQQQQQQQHQQPNRAR 1030



 Score = 29.3 bits (64), Expect = 3.1
 Identities = 16/78 (20%), Positives = 38/78 (48%), Gaps = 2/78 (2%)

Query: 123 QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ--GQEEKMRDVE 180
           Q+E + E++EM +   ++ +E  +      E+ +E ++  +++ EK    G E      +
Sbjct: 313 QKEPIPEEQEMDFRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQ 372

Query: 181 PAGGEAGEGSPQDNPTAQ 198
            +   A  G+P D+ + +
Sbjct: 373 TSSSSARPGTPSDHQSQE 390



 Score = 28.1 bits (61), Expect = 7.0
 Identities = 18/103 (17%), Positives = 50/103 (48%), Gaps = 9/103 (8%)

Query: 16   EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 75
            E  + +R       E +E  ++  E+  +Q+   Q Q++++ +Q+     Q++   +  +
Sbjct: 1169 EVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQ-----QQQPPQQPPQ 1223

Query: 76   LPEQKEKMWEQD----ERLREKEERMREQKMWQQVEKMREKKK 114
             P+Q++ +W  +      + +  +   +Q  ++ V+  ++KKK
Sbjct: 1224 QPQQQDSVWGMNHSTLHSVFQTNQSNNQQSNFEAVQSGKKKKK 1266



 Score = 27.7 bits (60), Expect = 9.1
 Identities = 16/89 (17%), Positives = 41/89 (46%), Gaps = 12/89 (13%)

Query: 104  QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE----------QEE 153
            +Q  + R K+K  +++ Q+Q  + Q+Q+    +Q  +  +Q++ +W           Q  
Sbjct: 1189 KQFLERRAKQKANQQRQQQQLPQQQQQQPP--QQPPQQPQQQDSVWGMNHSTLHSVFQTN 1246

Query: 154  KMREQEEKMREQEEKMQGQEEKMRDVEPA 182
            +   Q+      +   + +++KM   +P+
Sbjct: 1247 QSNNQQSNFEAVQSGKKKKKQKMVRADPS 1275


>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
          Length = 2803

 Score = 94.4 bits (233), Expect = 8e-20
 Identities = 64/242 (26%), Positives = 122/242 (50%), Gaps = 43/242 (17%)

Query: 1    MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
            + E+++  E++ K+ EE++   EQ++   EQ++K  E ++K  EQ++++ EQ+EK+ E++
Sbjct: 1436 LEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEK 1495

Query: 61   EKMWEQEEKMWEQQ------------------RLPEQKEKMWEQDERLREKEERMREQKM 102
            +K  +Q+ +  E +                  + PEQK +  EQ +++ EK+++  EQK 
Sbjct: 1496 DKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKY 1555

Query: 103  W----------QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKM---- 148
            W          Q ++ + E  +TQE++   QE+K ++ + +  +  EK++  EEK+    
Sbjct: 1556 WALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALL 1615

Query: 149  -----------WEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTA 197
                         QE + REQEEK    ++ +Q  +E     E   GE  E +P    T+
Sbjct: 1616 EKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTS 1675

Query: 198  QE 199
             E
Sbjct: 1676 PE 1677



 Score = 89.0 bits (219), Expect = 3e-18
 Identities = 51/184 (27%), Positives = 111/184 (60%), Gaps = 11/184 (5%)

Query: 1    MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
            ++++++  E++ +  E+++   EQ++K  E ++K  E+++K  EQ++K+ E+++K  EQ+
Sbjct: 1401 VKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQK 1460

Query: 61   EKMWEQEEKMWE-QQRLPEQKEKMWEQDERLREKEERMREQKM--------WQQVEKMRE 111
            +   EQ++K  E + +  EQK+++ EQ E++ E++++  +QK+           V +M++
Sbjct: 1461 DTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKD 1520

Query: 112  KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG 171
            +   Q +K  EQ+ + QEQ++ +   E+K Q  E+K W   +K    E+ ++  EE  Q 
Sbjct: 1521 RDLEQTDKAPEQKHQAQEQKDKV--SEKKDQALEQKYWALGQKDEALEQNIQALEENHQT 1578

Query: 172  QEEK 175
            QE++
Sbjct: 1579 QEQE 1582



 Score = 76.6 bits (187), Expect = 2e-14
 Identities = 52/215 (24%), Positives = 117/215 (54%), Gaps = 17/215 (7%)

Query: 1    MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
            +  +E +  ++  + +++E +  + E +++Q++ + EQ+ +  EQ++   EQ++K  E +
Sbjct: 1374 LEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKAL-EQKGRDLEQKDTALEQKDKALEPK 1432

Query: 61   EKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK---------MWQQVEKM- 109
            +K  E+++K  EQ+ ++PE+K+K  EQ +   E++++  E K         + +Q EK+ 
Sbjct: 1433 DKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIP 1492

Query: 110  REKKKTQEEKMQEQEEK-----MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164
             EK K  ++K++  E K     + E ++   EQ +K  EQ+ +  EQ++K+ E++++  E
Sbjct: 1493 EEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALE 1552

Query: 165  QEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199
            Q+    GQ+++  +      E    + +     QE
Sbjct: 1553 QKYWALGQKDEALEQNIQALEENHQTQEQESLVQE 1587



 Score = 75.1 bits (183), Expect = 5e-14
 Identities = 45/196 (22%), Positives = 115/196 (58%), Gaps = 7/196 (3%)

Query: 4    EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63
            ++R  E++K+   ++E++ +Q++K  E +E +  ++  +++++E +  + E + +Q++ +
Sbjct: 1350 KDRTSEQKKEPEPKDEVL-QQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKAL 1408

Query: 64   WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
             ++   + ++    EQK+K  E  ++  E++++  EQK   ++ + ++K   Q++   EQ
Sbjct: 1409 EQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQK--DKIPEEKDKALEQKDTALEQ 1466

Query: 124  EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAG 183
            ++K  E ++   EQ++++ EQ+EK+ E+++K  +Q  K+R  E K    E+ + +++   
Sbjct: 1467 KDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQ--KVRSVEHK--APEDTVAEMKDRD 1522

Query: 184  GEAGEGSPQDNPTAQE 199
             E  + +P+    AQE
Sbjct: 1523 LEQTDKAPEQKHQAQE 1538



 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 42/182 (23%), Positives = 112/182 (61%), Gaps = 7/182 (3%)

Query: 1    MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
            ++++++  E ++ +  ++  + +++E +  + E +++Q++ + EQ+ +  EQ++   EQ+
Sbjct: 1367 LQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKAL-EQKGRDLEQKDTALEQK 1425

Query: 61   EKMWEQEEK-MWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119
            +K  E ++K + E+ +  EQK+K+ E+ ++  E+++   EQK   +  + ++K   Q+++
Sbjct: 1426 DKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQK--DKALEPKDKDLEQKDR 1483

Query: 120  MQEQEEKMQEQEEMMWEQEEKMQEQ---EEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
            + EQ+EK+ E+++   +Q+ +  E    E+ + E +++  EQ +K  EQ+ + Q Q++K+
Sbjct: 1484 VLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKV 1543

Query: 177  RD 178
             +
Sbjct: 1544 SE 1545



 Score = 71.2 bits (173), Expect = 7e-13
 Identities = 47/194 (24%), Positives = 107/194 (55%), Gaps = 17/194 (8%)

Query: 18   EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM-------------WEQEEKMW 64
            E++  + E+K+   +++  EQ+++   ++E +Q++++ +             ++++E + 
Sbjct: 1336 EDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALH 1395

Query: 65   EQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQE 124
             + E + +Q +  EQK +  EQ +   E++++  E K     EK  +K   Q++K+ E++
Sbjct: 1396 VKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEK--DKALEQKDKIPEEK 1453

Query: 125  EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGG 184
            +K  EQ++   EQ++K  E ++K  EQ++++ EQ+EK+ E+++K    ++K+R VE    
Sbjct: 1454 DKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDK--ALDQKVRSVEHKAP 1511

Query: 185  EAGEGSPQDNPTAQ 198
            E      +D    Q
Sbjct: 1512 EDTVAEMKDRDLEQ 1525



 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 48/185 (25%), Positives = 93/185 (50%), Gaps = 22/185 (11%)

Query: 4    EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ------------EEKMQE 51
            E+ + E + +  E+ +   EQ+ + QEQ++K+ E++++  EQ            E+ +Q 
Sbjct: 1512 EDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQA 1571

Query: 52   QEEKMWEQEEKMWEQEEKMWEQQRLPEQK-EKMWEQDERLREKEERMREQKMWQQVEKMR 110
             EE    QE++   QE+K  + + L E+  EK+   +E+L    E+ +   +        
Sbjct: 1572 LEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGL-------- 1623

Query: 111  EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK-M 169
            E+   QE + +EQEEK    ++++ E +E    +EE   EQ+E     E+   EQ+ +  
Sbjct: 1624 EESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYW 1683

Query: 170  QGQEE 174
            +G+E+
Sbjct: 1684 RGRED 1688



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 41/189 (21%), Positives = 84/189 (44%), Gaps = 17/189 (8%)

Query: 10  REKKMREEEEMMREQEEKMQEQEEKMREQEEK-MWEQEEKMQEQEEKMWEQEEK------ 62
           RE  +   E++ ++ EE  +E+   + EQ +  + ++   +   EE       +      
Sbjct: 521 RELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSV 580

Query: 63  --MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
             + ++E  M E++ +PE  E+   +D  L    E   E+  W+      EKK+ + E++
Sbjct: 581 PGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWE------EKKQREAERL 634

Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
            ++ E  +E E  +  +E+ +++ E +  E+     E+EE   + E   Q   ++   V 
Sbjct: 635 PDRTEAREESEPEV--KEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVT 692

Query: 181 PAGGEAGEG 189
           P   EA  G
Sbjct: 693 PRSREAFGG 701



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 35/171 (20%), Positives = 86/171 (50%), Gaps = 21/171 (12%)

Query: 10  REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE-QEEKMQEQEEKMWEQEEKMWEQEE 68
           +  K+++  +     +   +    K+ ++EE + E  +E   E  +++ + E+K  E  E
Sbjct: 309 KPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSE 368

Query: 69  KMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQ 128
           K  E+   PE+ +   E  E L+ ++ ++ + K+          KK  +EK+ + EEK  
Sbjct: 369 KPPEKPAKPERVKT--ESSEALKAEKRKLIKDKVG---------KKHLKEKISKLEEK-- 415

Query: 129 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDV 179
                  + +EK + ++E+   ++++ R++E+K  ++EEK +  + +++ +
Sbjct: 416 -------KDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKI 459



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 38/168 (22%), Positives = 69/168 (41%), Gaps = 14/168 (8%)

Query: 3    EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
            +E R RE+E+K    +++++E +E    +EE   EQ+E     E+   EQ+ + W   E 
Sbjct: 1629 QEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGRED 1688

Query: 63   MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQE 122
            +  +++  W +      + K+W   E        +  Q       + RE     E    E
Sbjct: 1689 VALEQDTYWRELSC---ERKVWFPHE--------LDGQGARPHYTEERESTFLDEGPDDE 1737

Query: 123  QEEKMQEQ-EEMMWEQEEK--MQEQEEKMWEQEEKMREQEEKMREQEE 167
            QE  ++E      W  + K   +   +K  E E  + E    +  +EE
Sbjct: 1738 QEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEE 1785



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 28/130 (21%), Positives = 68/130 (52%), Gaps = 5/130 (3%)

Query: 2   REEERMREREKKMREE-EEMMREQEEKMQEQEEKMREQEEK----MWEQEEKMQEQEEKM 56
           + EE + E  K+ R E  + + + E+K +E  EK  E+  K      E  E ++ ++ K+
Sbjct: 336 KREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKL 395

Query: 57  WEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116
            + +      +EK+ + +   ++++K  +++ +  +K+E  +E+K   + E+ R+  K +
Sbjct: 396 IKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPE 455

Query: 117 EEKMQEQEEK 126
            +K+ + + K
Sbjct: 456 LKKISKPDLK 465



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 44/229 (19%), Positives = 97/229 (42%), Gaps = 39/229 (17%)

Query: 5   ERMREREKKMREEEEMMREQEEKMQ----EQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
           + + + EKK +E  E   E+  K +    E  E ++ ++ K+ + +   +  +EK+ + E
Sbjct: 354 KELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLE 413

Query: 61  EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQK-------------MWQQVE 107
           EK  ++E+K  +++R   +K++  +++++  +KEE+ ++ K                +V 
Sbjct: 414 EKK-DKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVR 472

Query: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWE-------------------QEEKMQEQEEKM 148
           K   K K       ++   ++ ++E+  E                   +E  +   E+  
Sbjct: 473 KTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLT 532

Query: 149 WEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAG--GEAGEGSPQDNP 195
            + EE  RE+   + EQ +   G +    D    G    A +G+P   P
Sbjct: 533 QDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVP 581



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 30/129 (23%), Positives = 65/129 (50%), Gaps = 12/129 (9%)

Query: 71   WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQ 130
            WE  ++P  K++  EQ +    K+E +      QQ +K  E K+  E K    +  + ++
Sbjct: 1342 WED-KVPGLKDRTSEQKKEPEPKDEVL------QQKDKTLEHKEVVEPK----DTAIYQK 1390

Query: 131  EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGS 190
            +E +  + E +++Q++ + EQ+ +  EQ++   EQ++K    ++K  + +    E  +  
Sbjct: 1391 DEALHVKNEAVKQQDKAL-EQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKI 1449

Query: 191  PQDNPTAQE 199
            P++   A E
Sbjct: 1450 PEEKDKALE 1458



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 37/161 (22%), Positives = 61/161 (37%), Gaps = 27/161 (16%)

Query: 4    EERMREREKKMREEEEMMREQE-----EKMQEQEEKMREQEEKMW---------EQEEKM 49
            EE+  E+ K M E+ E + E+      E+   QE + REQEEK W         ++    
Sbjct: 1597 EEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPT 1656

Query: 50   QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM 109
            +E+     ++    WE           PEQ  + W   E     +  + +   W+++   
Sbjct: 1657 REEPAGEQKELAPAWEDTS--------PEQDNRYWRGRE-----DVALEQDTYWRELSCE 1703

Query: 110  REKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE 150
            R+     E   Q       E+ E  +  E    EQE  + E
Sbjct: 1704 RKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLRE 1744



 Score = 35.8 bits (81), Expect = 0.033
 Identities = 28/122 (22%), Positives = 59/122 (48%), Gaps = 15/122 (12%)

Query: 75  RLPEQKEKMWEQDERLRE---KEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQE 131
           +L +++E + E  +  R    KE    E+K  +  EK  EK    E    E  E ++ ++
Sbjct: 333 KLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEK 392

Query: 132 EMMWEQEEKMQEQEEKMWEQEEKMREQEEKM------------REQEEKMQGQEEKMRDV 179
             + + +   +  +EK+ + EEK  ++++++            R++E+K   +EEK +D 
Sbjct: 393 RKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDT 452

Query: 180 EP 181
           +P
Sbjct: 453 KP 454



 Score = 29.3 bits (64), Expect = 3.1
 Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 10/147 (6%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMRE---QEEKMWEQEEKMQEQEEKMWEQ 59
           EEE+    EKK RE E  + ++ E  +E E +++E   ++ ++ E EE     EE+    
Sbjct: 617 EEEKDTWEEKKQREAER-LPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEEEDAT 675

Query: 60  EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLR----EKEERMREQKMWQQVEKMREKKKT 115
           + + + Q+      +  P  +E    ++  L+    EKE  +    +             
Sbjct: 676 KAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYI 735

Query: 116 QEEKMQEQEEKMQ--EQEEMMWEQEEK 140
           Q+E +    E  Q    EE+  E EE+
Sbjct: 736 QDETIPGYSETEQTISDEEIHDEPEER 762


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 91.3 bits (225), Expect = 7e-19
 Identities = 48/177 (27%), Positives = 112/177 (63%), Gaps = 4/177 (2%)

Query: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
           RE ER +ER ++ + + E  +E++ +  ++E+K R++ E+  E+E K +E+E++  E+ E
Sbjct: 32  RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91

Query: 62  KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVE-KMREKKKTQEEKM 120
           K   +  K  ++++  E+K++   + ++ +E++ER RE K  ++ + K R KKK ++E+ 
Sbjct: 92  K---ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148

Query: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
           +E+E   +E++    ++EE+ +++E    E++++   +E + R++E K + +++K R
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKER 205



 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 56/181 (30%), Positives = 120/181 (66%), Gaps = 12/181 (6%)

Query: 2   REEERMREREKKMRE-EEEMMREQ---EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMW 57
           R++ER REREK+ RE E+E  RE+   E+K +++ E+ +E+E K  E+E++ +E+ EK  
Sbjct: 36  RKKER-REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK-- 92

Query: 58  EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE 117
            +  K  ++++K   +QR   +++K  E+ ER RE ++R RE+K  ++ +K R K++ +E
Sbjct: 93  -ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR-RERKRKKRRKKKRRKERKRE 150

Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
           ++  ++E K +++++   E+ EK +E+  K  ++E + +E+ E+ +E++++ + ++E+ +
Sbjct: 151 KERGKRERKRKKRKK---EEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207

Query: 178 D 178
           D
Sbjct: 208 D 208



 Score = 74.7 bits (182), Expect = 7e-14
 Identities = 43/169 (25%), Positives = 108/169 (63%), Gaps = 8/169 (4%)

Query: 17  EEEMMREQEEKMQEQEEKMREQEEK--MWEQEEKMQEQEEKMWEQEEKMWEQE----EKM 70
           + E  R++E + +E+ ++ RE+E K    ++E+K +++ E+  E+E K  E+E    E+ 
Sbjct: 31  QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90

Query: 71  WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM-REKKKTQEEKMQEQEEKMQE 129
            +++R  ++++K  E+ +R R + ++ +E+K  ++  K  RE+K+ +  K + ++E+ +E
Sbjct: 91  EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150

Query: 130 QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
           +E    E++ K +++EE+  ++ E+ R++ +K RE++E+ + ++E+ ++
Sbjct: 151 KERGKRERKRKKRKKEERE-KKRERNRKERKKERERKERRERKKERKKE 198



 Score = 58.2 bits (139), Expect = 6e-09
 Identities = 31/131 (23%), Positives = 77/131 (58%), Gaps = 8/131 (6%)

Query: 58  EQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE 117
           E E K   +E +  +++R  E+K +  +++++ R+K ER +E++      K +E++K ++
Sbjct: 33  ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERE-----RKRKEREKQRK 87

Query: 118 EKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 177
           E+ +++  K +++++   ++E K + + E+  ++E K RE+E K R + ++ + +++K R
Sbjct: 88  ERREKERRKRKKEKK---KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144

Query: 178 DVEPAGGEAGE 188
                  E G+
Sbjct: 145 KERKREKERGK 155



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 23/80 (28%), Positives = 49/80 (61%), Gaps = 1/80 (1%)

Query: 105 QVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK-MR 163
           Q E  R+K++ + EK + + EK +++E    E++++ + +  K  E++ K RE++ K  R
Sbjct: 31  QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90

Query: 164 EQEEKMQGQEEKMRDVEPAG 183
           E+E + + +E+K R+ +  G
Sbjct: 91  EKERRKRKKEKKKRERKQRG 110



 Score = 36.2 bits (82), Expect = 0.026
 Identities = 15/72 (20%), Positives = 43/72 (59%)

Query: 106 VEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 165
           + K   +++++ +K + + EK + + E   ++E   +E++++   +  K RE++ K RE+
Sbjct: 25  ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84

Query: 166 EEKMQGQEEKMR 177
           + K + ++E+ +
Sbjct: 85  QRKERREKERRK 96


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 90.9 bits (224), Expect = 9e-19
 Identities = 50/173 (28%), Positives = 110/173 (63%), Gaps = 8/173 (4%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE----KMWEQEEKMQEQEEKMWE 58
           +E+  + +E+++ EE+   +   +KM+E E + +++EE    +  +QEE+ +  +E + +
Sbjct: 607 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK 666

Query: 59  QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEER---MREQKMWQQVEKMREKKKT 115
           ++E+  E+  K  E +RL EQ+E+   + ER RE+E R    REQ+  +Q  ++ E+++ 
Sbjct: 667 KKEEEQERLRKAAEAKRLAEQREQERREQER-REQERREQERREQERREQERQLAEQERR 725

Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168
           +E++  + E ++QE+E+ +  Q+E++Q + E+  ++EE+ R  E +++E++EK
Sbjct: 726 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 778



 Score = 88.6 bits (218), Expect = 4e-18
 Identities = 57/196 (29%), Positives = 115/196 (58%), Gaps = 20/196 (10%)

Query: 3   EEERMREREKKMREEEEMMREQ---EEKMQEQEEKMREQEEKMW------EQEEKMQEQE 53
           E+ER R    + +EE E +R Q   E+K +  EE   ++EE++       E+ E+M+E++
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 595

Query: 54  EKMWEQEEKMWEQEEKMWEQQRLPEQK-------EKMWEQDERLREKEERMREQKMWQQV 106
           +K  EQ+    +++ +  +++RL E+K       +KM E + R +++EE  R + + Q+ 
Sbjct: 596 KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE 655

Query: 107 EKMREKKKTQEEKMQEQEE--KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164
           E+ R ++  Q++K +EQE   K  E + +  ++E++ +EQE +  EQE + +E+ E+ R 
Sbjct: 656 EERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERR--EQERREQERREQERR 713

Query: 165 QEEKMQGQEEKMRDVE 180
           ++E+   ++E+ R+ E
Sbjct: 714 EQERQLAEQERRREQE 729



 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 56/197 (28%), Positives = 116/197 (58%), Gaps = 25/197 (12%)

Query: 1   MREEERMR------EREKKMREEEEMMREQ------EEKMQEQEEKMREQEEKMWEQEEK 48
           ++ EER+R      ER ++M+EE++   EQ      E+  + +EE++ E++ K     +K
Sbjct: 572 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK 631

Query: 49  MQEQEEKMWEQEEK-----MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW 103
           M+E E +  ++EE      + ++EE+   Q+ L ++KE   E+ ERLR+  E  R  +  
Sbjct: 632 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE---EEQERLRKAAEAKRLAEQR 688

Query: 104 QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ----EEKMWEQEEKMREQE 159
           +Q  + +E+++ +  + + +E++ +EQE  + EQE + +++    E ++ E+E+ +R Q+
Sbjct: 689 EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 748

Query: 160 EKM-REQEEKMQGQEEK 175
           E++ RE EEK + +E++
Sbjct: 749 EQLQRELEEKKKKEEQQ 765



 Score = 81.6 bits (200), Expect = 5e-16
 Identities = 53/189 (28%), Positives = 110/189 (58%), Gaps = 14/189 (7%)

Query: 1   MREEERMREREKKMREEEEM---MREQEEKMQEQEEKMREQEEKMWEQEEKMQE-QEEKM 56
           + E++R R  E K++ EE +   ++ +E   Q +EEK ++ E+K  + +EK ++ +EE++
Sbjct: 559 VEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERL 618

Query: 57  WEQEEKMWEQEEKMWEQQRLPEQKEK----MWEQDERLREKEERMREQKMWQQVEKMR-- 110
            E++ K     +KM E +   +Q+E+     W Q E    + + + ++K  ++ E++R  
Sbjct: 619 AEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKA 678

Query: 111 -EKKKTQEEKMQE-QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168
            E K+  E++ QE +E++ +EQE    E+ E+ + ++E+   ++E+ REQE    E+E  
Sbjct: 679 AEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERE-- 736

Query: 169 MQGQEEKMR 177
           +Q +E+ +R
Sbjct: 737 LQEREKALR 745



 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 48/161 (29%), Positives = 98/161 (60%), Gaps = 14/161 (8%)

Query: 1   MREEERMREREKKMREEEEMMREQEEK------MQEQEEKMREQE---EKMWEQEEKMQE 51
           + EE+  ++   K  EE E  R+QEE+      +Q++EE+ R QE   +K  E++E++++
Sbjct: 618 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRK 677

Query: 52  QEE--KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM 109
             E  ++ EQ E+   ++E+  +++R  E++E+   + ER   ++ER REQ+  Q   ++
Sbjct: 678 AAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAEREL 737

Query: 110 REKKKT---QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEK 147
           +E++K    Q+E++Q + E+ +++EE     E ++QE++EK
Sbjct: 738 QEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 778



 Score = 34.3 bits (77), Expect = 0.097
 Identities = 22/90 (24%), Positives = 53/90 (58%), Gaps = 11/90 (12%)

Query: 100 QKMWQQVEKMREKKKTQEEKMQE-QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 158
           +K  Q++E +R K++ ++ + Q+ +E+K +  EE+  ++EE++++  +         RE+
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQA--------RER 587

Query: 159 EEKMREQEEKMQGQEEKMRDVEPAGGEAGE 188
            E+M+E+++K    E+K   ++    +A E
Sbjct: 588 VEQMKEEKKKQ--IEQKFAQIDEKTEKAKE 615


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 90.9 bits (224), Expect = 9e-19
 Identities = 50/173 (28%), Positives = 110/173 (63%), Gaps = 8/173 (4%)

Query: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE----KMWEQEEKMQEQEEKMWE 58
           +E+  + +E+++ EE+   +   +KM+E E + +++EE    +  +QEE+ +  +E + +
Sbjct: 603 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK 662

Query: 59  QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEER---MREQKMWQQVEKMREKKKT 115
           ++E+  E+  K  E +RL EQ+E+   + ER RE+E R    REQ+  +Q  ++ E+++ 
Sbjct: 663 KKEEEQERLRKAAEAKRLAEQREQERREQER-REQERREQERREQERREQERQLAEQERR 721

Query: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168
           +E++  + E ++QE+E+ +  Q+E++Q + E+  ++EE+ R  E +++E++EK
Sbjct: 722 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 774



 Score = 89.4 bits (220), Expect = 3e-18
 Identities = 57/197 (28%), Positives = 116/197 (58%), Gaps = 20/197 (10%)

Query: 2   REEERMREREKKMREEEEMMREQ---EEKMQEQEEKMREQEEKMW------EQEEKMQEQ 52
           +E+ER R    + +EE E +R Q   E+K +  EE   ++EE++       E+ E+M+E+
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590

Query: 53  EEKMWEQEEKMWEQEEKMWEQQRLPEQK-------EKMWEQDERLREKEERMREQKMWQQ 105
           ++K  EQ+    +++ +  +++RL E+K       +KM E + R +++EE  R + + Q+
Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 650

Query: 106 VEKMREKKKTQEEKMQEQEE--KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 163
            E+ R ++  Q++K +EQE   K  E + +  ++E++ +EQE +  EQE + +E+ E+ R
Sbjct: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERR--EQERREQERREQER 708

Query: 164 EQEEKMQGQEEKMRDVE 180
            ++E+   ++E+ R+ E
Sbjct: 709 REQERQLAEQERRREQE 725



 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 56/197 (28%), Positives = 116/197 (58%), Gaps = 25/197 (12%)

Query: 1   MREEERMR------EREKKMREEEEMMREQ------EEKMQEQEEKMREQEEKMWEQEEK 48
           ++ EER+R      ER ++M+EE++   EQ      E+  + +EE++ E++ K     +K
Sbjct: 568 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKK 627

Query: 49  MQEQEEKMWEQEEK-----MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMW 103
           M+E E +  ++EE      + ++EE+   Q+ L ++KE   E+ ERLR+  E  R  +  
Sbjct: 628 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE---EEQERLRKAAEAKRLAEQR 684

Query: 104 QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQ----EEKMWEQEEKMREQE 159
           +Q  + +E+++ +  + + +E++ +EQE  + EQE + +++    E ++ E+E+ +R Q+
Sbjct: 685 EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 744

Query: 160 EKM-REQEEKMQGQEEK 175
           E++ RE EEK + +E++
Sbjct: 745 EQLQRELEEKKKKEEQQ 761



 Score = 81.6 bits (200), Expect = 5e-16
 Identities = 53/189 (28%), Positives = 110/189 (58%), Gaps = 14/189 (7%)

Query: 1   MREEERMREREKKMREEEEM---MREQEEKMQEQEEKMREQEEKMWEQEEKMQE-QEEKM 56
           + E++R R  E K++ EE +   ++ +E   Q +EEK ++ E+K  + +EK ++ +EE++
Sbjct: 555 VEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERL 614

Query: 57  WEQEEKMWEQEEKMWEQQRLPEQKEK----MWEQDERLREKEERMREQKMWQQVEKMR-- 110
            E++ K     +KM E +   +Q+E+     W Q E    + + + ++K  ++ E++R  
Sbjct: 615 AEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKA 674

Query: 111 -EKKKTQEEKMQE-QEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 168
            E K+  E++ QE +E++ +EQE    E+ E+ + ++E+   ++E+ REQE    E+E  
Sbjct: 675 AEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERE-- 732

Query: 169 MQGQEEKMR 177
           +Q +E+ +R
Sbjct: 733 LQEREKALR 741



 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 48/161 (29%), Positives = 98/161 (60%), Gaps = 14/161 (8%)

Query: 1   MREEERMREREKKMREEEEMMREQEEK------MQEQEEKMREQE---EKMWEQEEKMQE 51
           + EE+  ++   K  EE E  R+QEE+      +Q++EE+ R QE   +K  E++E++++
Sbjct: 614 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRK 673

Query: 52  QEE--KMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM 109
             E  ++ EQ E+   ++E+  +++R  E++E+   + ER   ++ER REQ+  Q   ++
Sbjct: 674 AAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAEREL 733

Query: 110 REKKKT---QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEK 147
           +E++K    Q+E++Q + E+ +++EE     E ++QE++EK
Sbjct: 734 QEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 774



 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 53/218 (24%), Positives = 117/218 (53%), Gaps = 38/218 (17%)

Query: 14  MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 73
           ++    +  + +EK +++ E +R +EE   EQ  + + +E+K    EE   ++EE++   
Sbjct: 520 IKRNTPLRMDPKEKERQRLENLRRKEEA--EQLRRQKVEEDKRRRLEEVKLKREERL--- 574

Query: 74  QRLPEQKEKMWEQDERLREKEERMREQKMWQ---QVEKMREK--------KKTQEEKMQE 122
           +++ + +E++    E+++E++++  EQK  Q   + EK +E+        KK   +KM+E
Sbjct: 575 RKVLQARERV----EQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 630

Query: 123 QEEKMQEQEE---MMW--EQEEKMQEQE---EKMWEQEEKMR----------EQEEKMRE 164
            E + +++EE   + W  ++EE+ + QE   +K  E++E++R          ++E++ RE
Sbjct: 631 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 690

Query: 165 QEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQEIMQ 202
           QE + Q + E+ R  +    +  + + Q+    QE +Q
Sbjct: 691 QERREQERREQERREQERREQERQLAEQERRREQERLQ 728


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.304    0.120    0.332 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,970,555
Number of Sequences: 37866
Number of extensions: 830846
Number of successful extensions: 105961
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1991
Number of HSP's successfully gapped in prelim test: 938
Number of HSP's that attempted gapping in prelim test: 7475
Number of HSP's gapped (non-prelim): 31384
length of query: 238
length of database: 18,247,518
effective HSP length: 99
effective length of query: 139
effective length of database: 14,498,784
effective search space: 2015330976
effective search space used: 2015330976
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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