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Search of human proteins with 239752280
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239752280 PREDICTED: similar to family with sequence
similarity 48, member B2 [Homo sapiens]
(779 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239752280 PREDICTED: similar to family with sequence similari... 1575 0.0
gi|210032463 family with sequence similarity 48, member B2 [Homo... 1556 0.0
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens] 1368 0.0
gi|98961135 family with sequence similarity 48, member A isoform... 650 0.0
gi|8923735 family with sequence similarity 48, member A isoform ... 622 e-178
gi|110832843 TBP-associated factor 4 [Homo sapiens] 65 2e-10
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 64 4e-10
gi|150170670 piccolo isoform 2 [Homo sapiens] 63 9e-10
gi|150378539 piccolo isoform 1 [Homo sapiens] 63 9e-10
gi|7662236 TSC22 domain family, member 2 [Homo sapiens] 62 2e-09
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 62 3e-09
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 62 3e-09
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 62 3e-09
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 61 5e-09
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 60 1e-08
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 60 1e-08
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 60 1e-08
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 59 1e-08
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 59 1e-08
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 58 3e-08
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 57 7e-08
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 57 9e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni... 56 1e-07
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora... 55 2e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 55 2e-07
gi|7662346 ADNP homeobox 2 [Homo sapiens] 55 2e-07
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 55 2e-07
gi|119943102 CREB binding protein isoform b [Homo sapiens] 55 3e-07
gi|119943104 CREB binding protein isoform a [Homo sapiens] 55 3e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 54 4e-07
>gi|239752280 PREDICTED: similar to family with sequence similarity
48, member B2 [Homo sapiens]
Length = 779
Score = 1575 bits (4078), Expect = 0.0
Identities = 779/779 (100%), Positives = 779/779 (100%)
Query: 1 MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS
Sbjct: 1 MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
Query: 61 NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE
Sbjct: 61 NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
Query: 121 LPPARHILLRPTMQTLAPEVKTMTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVAC 180
LPPARHILLRPTMQTLAPEVKTMTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVAC
Sbjct: 121 LPPARHILLRPTMQTLAPEVKTMTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVAC 180
Query: 181 TANRLLYNKQKMNTDPMEQCLQRYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQP 240
TANRLLYNKQKMNTDPMEQCLQRYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQP
Sbjct: 181 TANRLLYNKQKMNTDPMEQCLQRYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQP 240
Query: 241 CELNITKAGSCVDTWKGRPCDLAVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFR 300
CELNITKAGSCVDTWKGRPCDLAVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFR
Sbjct: 241 CELNITKAGSCVDTWKGRPCDLAVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFR 300
Query: 301 HAWEAGCQAWDTKPNIMQSFNDPLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSE 360
HAWEAGCQAWDTKPNIMQSFNDPLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSE
Sbjct: 301 HAWEAGCQAWDTKPNIMQSFNDPLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSE 360
Query: 361 TDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGE 420
TDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGE
Sbjct: 361 TDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGE 420
Query: 421 KHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALA 480
KHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALA
Sbjct: 421 KHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALA 480
Query: 481 AAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNV 540
AAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNV
Sbjct: 481 AAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNV 540
Query: 541 EGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQF 600
EGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQF
Sbjct: 541 EGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQF 600
Query: 601 FLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLST 660
FLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLST
Sbjct: 601 FLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLST 660
Query: 661 QGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLL 720
QGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLL
Sbjct: 661 QGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLL 720
Query: 721 QPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 779
QPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP
Sbjct: 721 QPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 779
>gi|210032463 family with sequence similarity 48, member B2 [Homo
sapiens]
Length = 817
Score = 1556 bits (4029), Expect = 0.0
Identities = 779/817 (95%), Positives = 779/817 (95%), Gaps = 38/817 (4%)
Query: 1 MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS
Sbjct: 1 MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
Query: 61 NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE
Sbjct: 61 NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
Query: 121 LPPA--------------------------------------RHILLRPTMQTLAPEVKT 142
LPPA RHILLRPTMQTLAPEVKT
Sbjct: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAPEVKT 180
Query: 143 MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ 202
MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ
Sbjct: 181 MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ 240
Query: 203 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNITKAGSCVDTWKGRPCDL 262
RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNITKAGSCVDTWKGRPCDL
Sbjct: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNITKAGSCVDTWKGRPCDL 300
Query: 263 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFND 322
AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFND
Sbjct: 301 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFND 360
Query: 323 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 382
PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG
Sbjct: 361 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 420
Query: 383 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 442
KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF
Sbjct: 421 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480
Query: 443 PPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVP 502
PPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVP
Sbjct: 481 PPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVP 540
Query: 503 LIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGS 562
LIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGS
Sbjct: 541 LIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGS 600
Query: 563 GAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVL 622
GAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVL
Sbjct: 601 GAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVL 660
Query: 623 TGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGL 682
TGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGL
Sbjct: 661 TGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGL 720
Query: 683 QPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQP 742
QPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQP
Sbjct: 721 QPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQP 780
Query: 743 VFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 779
VFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP
Sbjct: 781 VFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 817
>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
Length = 887
Score = 1368 bits (3541), Expect = 0.0
Identities = 724/887 (81%), Positives = 734/887 (82%), Gaps = 108/887 (12%)
Query: 1 MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
MDRDLEQALDR ENI EIAQQR PRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS
Sbjct: 1 MDRDLEQALDRAENIIEIAQQRPPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
Query: 61 NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE
Sbjct: 61 NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
Query: 121 LPPA--------------------------------------RHILLRPTMQTLAPEVKT 142
LPPA RHILLRPTMQTLA +VK
Sbjct: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAHDVKM 180
Query: 143 MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ 202
MTRDG+KWSQEDK LESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPM++CLQ
Sbjct: 181 MTRDGQKWSQEDKLQLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMKRCLQ 240
Query: 203 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNITKAGSCVDTWKGRPCDL 262
RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNI KAGSCVDTWKGRPCDL
Sbjct: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNIAKAGSCVDTWKGRPCDL 300
Query: 263 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFND 322
AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPF A EAGCQAWDTKP+IMQSFND
Sbjct: 301 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFGFALEAGCQAWDTKPSIMQSFND 360
Query: 323 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 382
PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG
Sbjct: 361 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 420
Query: 383 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 442
KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF
Sbjct: 421 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480
Query: 443 PPQQAGSPLKRPF-------------PAAAPAVAAAAPAPAPAPAAAPALAA-------- 481
PPQQAGSPLKRPF AAA A AAAAPAPA A AAAPALAA
Sbjct: 481 PPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAA 540
Query: 482 --------------AAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQ 527
AA AAA AAPSHSQKPSVPLI+ASR PAA PT+F+KIAPAIQ
Sbjct: 541 AAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQ 600
Query: 528 VRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARP 587
+RTGSTGLKA NVEGPV+GAQ LG SFKPVQAPGSGAPAPAGISGS LQSSGGPLPDARP
Sbjct: 601 LRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARP 660
Query: 588 GAVQASSPAPLQFFLNTPEGLRPLT-LQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHP 646
GAVQASSPAPLQFFLNTPEGLRPLT LQVPQG AVLTGPQQQSHQLVSLQQLQQPTAAHP
Sbjct: 661 GAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHP 720
Query: 647 PQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQL 706
PQPGPQGS LGLSTQGQAFPAQQLL VN T A SGLQPQPQ AVLSLLGSAQVPQQGVQL
Sbjct: 721 PQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQL 780
Query: 707 PFVL-GQQPQ---PLLLLQPQ------------------------------PQPQQIQLQ 732
P VL QQPQ P L LQPQ QPQ IQLQ
Sbjct: 781 PSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQLRVLQQPQHIQLQ 840
Query: 733 TQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 779
TQ LRVLQQPVFLATGAVQIVQPHPGVQ GSQLV QRK GKPTPPAP
Sbjct: 841 TQQLRVLQQPVFLATGAVQIVQPHPGVQVGSQLVDQRKEGKPTPPAP 887
>gi|98961135 family with sequence similarity 48, member A isoform a
[Homo sapiens]
Length = 779
Score = 650 bits (1677), Expect = 0.0
Identities = 403/826 (48%), Positives = 486/826 (58%), Gaps = 98/826 (11%)
Query: 1 MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
M + LE ALDR E + E A+QR P+R+Y K++ +KLYD+Y+EEC KEPE ++LR
Sbjct: 1 MQQALELALDRAEYVIESARQRPPKRKYLSSGRKSVFQKLYDLYIEECEKEPE-VKKLRR 59
Query: 61 NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
NVNLLEKLV +E+L CL+VNLYPGN+GYS+ML+ ++GS +ETIRLPYEE LL+YLDAEE
Sbjct: 60 NVNLLEKLVMQETLSCLVVNLYPGNEGYSLMLRGKNGSDSETIRLPYEEGELLEYLDAEE 119
Query: 121 LPP--------------------------------------ARHILLRPTMQTLAPEVKT 142
LPP +RHILLRPTMQTL +V +
Sbjct: 120 LPPILVDLLEKSQVNIFHCGCVIAEIRDYRQSSNMKSPGYQSRHILLRPTMQTLICDVHS 179
Query: 143 MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ 202
+T D KW+QEDK LESQLILATAEPLCLDPS+AV CTANRLLYNKQKMNT PM++C +
Sbjct: 180 ITSDNHKWTQEDKLLLESQLILATAEPLCLDPSIAVTCTANRLLYNKQKMNTRPMKRCFK 239
Query: 203 RYSWPSVKPQQEQSDCPPPPELRVSTSGQK-EERKVGQPCELNITKAGSCVDTWKGRPCD 261
RYS S+ QQ+ S CPPPP+LR+ QK +ERK GQ +L I+KAG+CVD WK PC+
Sbjct: 240 RYSRSSLNRQQDLSHCPPPPQLRLLDFLQKRKERKAGQHYDLKISKAGNCVDMWKRSPCN 299
Query: 262 LAVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFN 321
LA+PSEVDVEK AK +S+ + D Q VWPA +V+D + EAG Q TK I+QS
Sbjct: 300 LAIPSEVDVEKYAKVEKSIKSDDSQPTVWPAHDVKDDYVFECEAGTQYQKTKLTILQSLG 359
Query: 322 DPLLCGKIRPRKKARQK-SQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKG 380
DPL GKI+P K + SQ SP DDHS GS+TDA R V+Q QE VQ++ K
Sbjct: 360 DPLYYGKIQPCKADEESDSQMSPSHSSTDDHSNWFIIGSKTDAERVVNQYQELVQNEAKC 419
Query: 381 PGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGN 440
P KMSHSSSG AS+SQ+S K +Q + V VQSSV GKG KH PP +LPSSSG SSGN
Sbjct: 420 PVKMSHSSSGSASLSQVSPGKETDQTETVSVQSSVLGKGVKHRPPPIKLPSSSGNSSSGN 479
Query: 441 SFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPS 500
F PQQ S LK P P P+ P++ P +K S
Sbjct: 480 YFTPQQTSSFLKSP-----------TPPPSSKPSSIP-------------------RKSS 509
Query: 501 VPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAP 560
V L + S PAA P + A QV S GL NV G V GAQ L P+
Sbjct: 510 VDLNQVSMLSPAALSPASSSQRTTATQVMANSAGLNFINVVGSVCGAQALMSGSNPMLGC 569
Query: 561 GSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLT-LQVPQGW 619
+GA PAGI+ SGL SGG LP+A P A+QA+S A + F L LRPL LQ+P G
Sbjct: 570 NTGAITPAGINLSGLLPSGGLLPNALPSAMQAASQAGVPFGLKNTSSLRPLNLLQLPGGS 629
Query: 620 AVLTGPQQQSHQLVSL--QQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTG 677
+ QQQ QL QQ QQPT P QPG QGS G ++Q QA AQQ +NLTG
Sbjct: 630 LIFNTLQQQQQQLSQFTPQQPQQPTTCSPQQPGEQGSEQGSTSQEQALSAQQAAVINLTG 689
Query: 678 AGSGLQPQPQAAVLSLLGSAQ------VPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQL 731
GS + Q QAAVLS LGSA+ +PQQ QL QQ Q
Sbjct: 690 VGSFM--QSQAAVLSQLGSAENRPEQSLPQQRFQLSSAFQQQQQ---------------- 731
Query: 732 QTQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPP 777
Q Q LR LQ + +A A Q Q H GSQ + K G PT P
Sbjct: 732 QIQQLRFLQHQMAMAAAAAQTAQLHHHRHTGSQSKSKMKRGTPTTP 777
>gi|8923735 family with sequence similarity 48, member A isoform b
[Homo sapiens]
Length = 733
Score = 622 bits (1605), Expect = e-178
Identities = 371/740 (50%), Positives = 453/740 (61%), Gaps = 75/740 (10%)
Query: 1 MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
M + LE ALDR E + E A+QR P+R+Y K++ +KLYD+Y+EEC KEPE Q+LR
Sbjct: 1 MQQALELALDRAEYVIESARQRPPKRKYLSSGRKSVFQKLYDLYIEECEKEPEVKQKLRR 60
Query: 61 NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
NVNLLEKLV +E+L CL+VNLYPGN+GYS+ML+ ++GS +ETIRLPYEE LL+YLDAEE
Sbjct: 61 NVNLLEKLVMQETLSCLVVNLYPGNEGYSLMLRGKNGSDSETIRLPYEEGELLEYLDAEE 120
Query: 121 LPP--------------------------------------ARHILLRPTMQTLAPEVKT 142
LPP +RHILLRPTMQTL +V +
Sbjct: 121 LPPILVDLLEKSQVNIFHCGCVIAEIRDYRQSSNMKSPGYQSRHILLRPTMQTLICDVHS 180
Query: 143 MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ 202
+T D KW+QEDK LESQLILATAEPLCLDPS+AV CTANRLLYNKQKMNT PM++C +
Sbjct: 181 ITSDNHKWTQEDKLLLESQLILATAEPLCLDPSIAVTCTANRLLYNKQKMNTRPMKRCFK 240
Query: 203 RYSWPSVKPQQEQSDCPPPPELRVSTSGQK-EERKVGQPCELNITKAGSCVDTWKGRPCD 261
RYS S+ QQ+ S CPPPP+LR+ QK +ERK GQ +L I+KAG+CVD WK PC+
Sbjct: 241 RYSRSSLNRQQDLSHCPPPPQLRLLDFLQKRKERKAGQHYDLKISKAGNCVDMWKRSPCN 300
Query: 262 LAVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFN 321
LA+PSEVDVEK AK +S+ + D Q VWPA +V+D + EAG Q TK I+QS
Sbjct: 301 LAIPSEVDVEKYAKVEKSIKSDDSQPTVWPAHDVKDDYVFECEAGTQYQKTKLTILQSLG 360
Query: 322 DPLLCGKIRPRKKARQK-SQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKG 380
DPL GKI+P K + SQ SP DDHS GS+TDA R V+Q QE VQ++ K
Sbjct: 361 DPLYYGKIQPCKADEESDSQMSPSHSSTDDHSNWFIIGSKTDAERVVNQYQELVQNEAKC 420
Query: 381 PGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGN 440
P KMSHSSSG AS+SQ+S K +Q + V VQSSV GKG KH PP +LPSSSG SSGN
Sbjct: 421 PVKMSHSSSGSASLSQVSPGKETDQTETVSVQSSVLGKGVKHRPPPIKLPSSSGNSSSGN 480
Query: 441 SFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPS 500
F PQQ S LK P P P+ P++ P +K S
Sbjct: 481 YFTPQQTSSFLKSP-----------TPPPSSKPSSIP-------------------RKSS 510
Query: 501 VPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAP 560
V L + S PAA P + A QV S GL NV G V GAQ L P+
Sbjct: 511 VDLNQVSMLSPAALSPASSSQRTTATQVMANSAGLNFINVVGSVCGAQALMSGSNPMLGC 570
Query: 561 GSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLT-LQVPQGW 619
+GA PAGI+ SGL SGG LP+A P A+QA+S A + F L LRPL LQ+P G
Sbjct: 571 NTGAITPAGINLSGLLPSGGLLPNALPSAMQAASQAGVPFGLKNTSSLRPLNLLQLPGGS 630
Query: 620 AVLTGPQQQSHQLVSL--QQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTG 677
+ QQQ QL QQ QQPT P QPG QGS G ++Q QA AQQ +NLTG
Sbjct: 631 LIFNTLQQQQQQLSQFTPQQPQQPTTCSPQQPGEQGSEQGSTSQEQALSAQQAAVINLTG 690
Query: 678 AGSGLQPQPQAAVLSLLGSA 697
GS + Q QAA +++L ++
Sbjct: 691 VGSFM--QSQAAAVAILAAS 708
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 65.1 bits (157), Expect = 2e-10
Identities = 110/417 (26%), Positives = 147/417 (35%), Gaps = 65/417 (15%)
Query: 357 PGSETDAGRAVSQAQES----VQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQ--PDPVW 410
PG AG +Q + S +S ++GPA++ L P P +
Sbjct: 184 PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF 243
Query: 411 VQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRP--FPAAAPAVAAAAPA 468
V ++ PP P++ PP A + L RP PA P A A P
Sbjct: 244 VGAAAPPAPAAPSPPAAPAPAAPAAAPP----PPPPAPATLARPPGHPAGPPTAAPAVPP 299
Query: 469 PAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQ- 527
PA A A AA A A AAGG A Q A A P R V+ AP
Sbjct: 300 PAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQ 359
Query: 528 --VRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDA 585
+G A+ V GP + + P APG+ P G +G+ QS P A
Sbjct: 360 TLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSL-SRTPTA 418
Query: 586 RPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAH 645
++A+ TP L P Q PQ + Q+ QL
Sbjct: 419 TTSGIRATL---------TPTVLAPRLPQPPQNPTNI-----QNFQL------------- 451
Query: 646 PPQPGPQGSTLGLSTQGQ--AFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQ- 702
P G L S GQ P Q L + A + QPQ A ++ P Q
Sbjct: 452 -----PPGMVLVRSENGQLLMIPQQALAQMQ---AQAHAQPQTTMAPRPATPTSAPPVQI 503
Query: 703 -GVQLPF--VLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQ-----QPVFLATGAVQ 751
VQ P ++ +Q P +++ Q Q Q QP LQ QP + GA Q
Sbjct: 504 STVQAPGTPIIARQVTPTTIIK---QVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQ 557
Score = 61.6 bits (148), Expect = 3e-09
Identities = 93/350 (26%), Positives = 119/350 (34%), Gaps = 38/350 (10%)
Query: 387 SSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPP-PRTQLPSSSGKISSGNSFPPQ 445
+ +GPA+ ++ + PE P + G PP PR L + + PP
Sbjct: 71 AGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPP 130
Query: 446 QAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIK 505
+ + P PAAA AA P PAPA A PA AA A A G P P
Sbjct: 131 EGSAGSCAPVPAAA--AVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG----- 183
Query: 506 ASRRRPAAGRPTRFVKIAPAIQVRTGSTGL------KATNVEGPVRGAQVLGCSFKPVQA 559
P G+P A Q GS L A V G L KP A
Sbjct: 184 -----PGPGKPAG----PGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPA-A 233
Query: 560 PGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGW 619
PG+ P + + + P P A P ++ P P P TL P G
Sbjct: 234 PGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPP-------PPPPAPATLARPPGH 286
Query: 620 AVLTGPQQQSHQLVSLQQLQQ-PTAAHPPQPGP-QGSTLGLSTQ--GQAFPAQQLLNVNL 675
GP + + Q +A P P P G G+S Q A A V
Sbjct: 287 P--AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKA 344
Query: 676 TGAGSGLQPQPQAA-VLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQP 724
+Q P AA L+ G A V P + G P P + P P
Sbjct: 345 ESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAP 394
Score = 50.4 bits (119), Expect = 6e-06
Identities = 102/400 (25%), Positives = 132/400 (33%), Gaps = 76/400 (19%)
Query: 412 QSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAP 471
Q + S H PRT ++ + GN +GSP A A AAPA
Sbjct: 32 QLAASAAHHHHLAPRTPEVRAAAAGALGNHVV---SGSP------AGAAGAGPAAPAEG- 81
Query: 472 APAAAPALAAAAVAAAAGGAAPSHSQKPSV--PLIKASRRRPAAGRPTRFVKIAPAIQVR 529
AP AAP A A GG P PS PL+ A PAA K+ P +
Sbjct: 82 APGAAPEPPPAG-RARPGGGGPQRPGPPSPRRPLVPAGPAPPAA-------KLRPPPEGS 133
Query: 530 TGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGIS---------GSGLQSSGG 580
GS PV A + +P A + PA ++ G G G
Sbjct: 134 AGSC--------APVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG 185
Query: 581 PLPDARPGAVQ-------------ASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQ 627
P A PGA Q A++PA + N P L PL G + T P
Sbjct: 186 PGKPAGPGAAQTLNGSAALLNSHHAAAPA-VSLVNNGPAALLPLPKPAAPGTVIQTPPFV 244
Query: 628 QSHQLVSLQQLQQPT-------AAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGS 680
+ + P AA PP P P +TL A P A
Sbjct: 245 GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPT---------AAP 295
Query: 681 GLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQP-LLLLQPQPQPQQIQLQTQPLRVL 739
+ P A G+A P P + QP P P P + P RV+
Sbjct: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVK----AESPKRVV 351
Query: 740 QQPVFLATGAVQIVQPHPGVQAGSQLVG-QRKGGKPTPPA 778
Q A + P A S ++G +G P+P A
Sbjct: 352 QA---APPAAQTLAASGPASTAASMVIGPTMQGALPSPAA 388
Score = 40.0 bits (92), Expect = 0.008
Identities = 92/382 (24%), Positives = 140/382 (36%), Gaps = 86/382 (22%)
Query: 403 PEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAV 462
P P P Q+ + + + PP + S +G++ PQQA + ++ A A A
Sbjct: 434 PRLPQPP--QNPTNIQNFQLPPGMVLVRSENGQLL----MIPQQALAQMQ----AQAHAQ 483
Query: 463 AAAAPAPAPA-PAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVK 521
AP PA P +AP + + V A G Q +IK + +P+ ++
Sbjct: 484 PQTTMAPRPATPTSAPPVQISTVQAP--GTPIIARQVTPTTIIKQVSQAQTTVQPSATLQ 541
Query: 522 IAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAG------------ 569
+P +Q + G T G Q G + V PG+ + A
Sbjct: 542 RSPGVQPQLVLGGAAQTASLGTATAVQT-GTPQRTV--PGATTTSSAATETMENVKKCKN 598
Query: 570 -------ISGSGLQSSGGP------LPDARPGAVQA------------SSPAP--LQFFL 602
++ SG QS+ + + G ++A SSP P + F
Sbjct: 599 FLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLK 658
Query: 603 NTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQG 662
+ LR LT P A + QQQ PP P Q +T L+
Sbjct: 659 RSLPALRQLT---PDSAAFIQQSQQQ-----------------PPPPTSQATT-ALTAVV 697
Query: 663 QAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVP--QQGVQLPFVLGQQPQPLLLL 720
+ Q+ S LQP VLSL QV +QG P V+ Q P+P L+
Sbjct: 698 LSSSVQRTAGKTAATVTSALQPP----VLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALI 753
Query: 721 QPQPQPQQIQLQTQPLRVLQQP 742
+P Q+ L P+ L+QP
Sbjct: 754 ----RPPQVTLTQTPMVALRQP 771
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 64.3 bits (155), Expect = 4e-10
Identities = 126/451 (27%), Positives = 161/451 (35%), Gaps = 81/451 (17%)
Query: 354 CLRPGSETDAGRAVSQAQESV---QSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVW 410
C P SE G + Q+ S+ Q PG S PA L PDP
Sbjct: 652 CSPPVSE---GPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQ----HFPDPAM 704
Query: 411 VQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPA-- 468
+ V PPP T +P+ G+ + PP Q PL +P P P V A P
Sbjct: 705 SFAPVL------PPPSTPMPTGPGQPA-----PPGQQPPPLAQPTP--LPQVLAPQPVVP 751
Query: 469 --PAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRF--VKIAP 524
P P P P LA A+ A P Q P PL +P A P + + + P
Sbjct: 752 LQPVP-PHLPPYLAPASQVGAPAQLKP--LQMPQAPL------QPLAQVPPQMPPIPVVP 802
Query: 525 AIQVRTGSTGLK------ATNVEGPVRGAQVLGCSFKP-VQAPGSGAPAPAGISGSGLQS 577
I G GL T PV Q F P V P AP P LQ+
Sbjct: 803 PITPLAGIDGLPPALPDLPTATVPPVPPPQY----FSPAVILPSLAAPLPPASPALPLQA 858
Query: 578 SGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQ 637
P P P A+ + P N P + PL P G A L+ H V+
Sbjct: 859 VKLPHPPGAPLAMPCRTIVP-----NAPATI-PLLAVAPPGVAALS-----IHSAVAQLP 907
Query: 638 LQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLL-GS 696
Q A PQ P T P + N+ T L PQP +L
Sbjct: 908 GQPVYPAAFPQMAP--------TDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQ 959
Query: 697 AQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQI-------QLQTQPLR--VLQQPVFLAT 747
+P Q V LP + PQP+L QP PQ + ++ +PL+ + +Q AT
Sbjct: 960 PTLPPQPV-LPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAAT 1018
Query: 748 GAVQIVQPHPGVQAGSQLVGQRKGGKPTPPA 778
QI+ HP A V + P PPA
Sbjct: 1019 PGSQILLGHPAPYAVD--VAAQVPTVPVPPA 1047
Score = 37.7 bits (86), Expect = 0.041
Identities = 59/250 (23%), Positives = 94/250 (37%), Gaps = 27/250 (10%)
Query: 371 QESVQSKVKGP---GKMSHSSSGPASVSQLSSWKTPEQPD---PVWVQSSVSGKGEKHPP 424
+ES QS+ P + H+ + ++ PE P+ P+ + S + P
Sbjct: 1289 EESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAP 1348
Query: 425 PRTQLPS-------SSGKISS--GNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAA 475
+ QL S +S ++ S G S PP +PL P++ P A APA +
Sbjct: 1349 YKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLA---PSSPPVTALPQDGAAPATST 1405
Query: 476 APALAAAAVAAAAGGAAP---SHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGS 532
P A+ + A G P + + S PL + + P A +P V +AP +
Sbjct: 1406 MPEPASGTASQAGGPGTPQGLTSELETSQPLAE-THEAPLAVQPL-VVGLAPCTPAPEAA 1463
Query: 533 TGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPA---PAGISGSGLQSSGGPLPDARPGA 589
+ A+ P+ P G PA PA + L +S P P P
Sbjct: 1464 STRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGP-T 1522
Query: 590 VQASSPAPLQ 599
V P+ L+
Sbjct: 1523 VPPQPPSALE 1532
Score = 35.8 bits (81), Expect = 0.16
Identities = 99/451 (21%), Positives = 137/451 (30%), Gaps = 88/451 (19%)
Query: 343 PWQPFPDDHSACLRPGSETDAG---RAVSQAQESVQSKVKGPGKM------------SHS 387
P QP P L P S+ A + + Q +Q + P +M +
Sbjct: 751 PLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGI 810
Query: 388 SSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQA 447
P ++ L + P P P + P LPS + + + P QA
Sbjct: 811 DGLPPALPDLPTATVPPVPPPQYFS------------PAVILPSLAAPLPPASPALPLQA 858
Query: 448 GSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKAS 507
+K P P AP APA P LA A AA + +Q P P+
Sbjct: 859 ---VKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVY--- 912
Query: 508 RRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAP 567
P F ++A P P S
Sbjct: 913 --------PAAFPQMA--------------------------------PTDVPPSPHHTV 932
Query: 568 AGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQ 627
+ + Q + P P P V P + P+ RP +P + PQ
Sbjct: 933 QNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPP--QPMLPPQP 990
Query: 628 QSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQ 687
+L +P H P+ +T G S PA ++V A P P
Sbjct: 991 VLPPQPALPVRPEPLQPHLPEQAAPAATPG-SQILLGHPAPYAVDV---AAQVPTVPVPP 1046
Query: 688 AAVLSLLGSAQVPQQGVQLPFVLGQQPQ-PLLLLQPQPQPQQIQLQTQPLRVLQQPVFLA 746
AAVLS P V LP PQ P L Q + QT L P
Sbjct: 1047 AAVLS------PPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPL-- 1098
Query: 747 TGAVQIVQPHPGVQAGSQLVGQRKGGKPTPP 777
G I P P VQ + V + + + PP
Sbjct: 1099 PGGPGIASPCPTVQLTVEPVQEEQASQDKPP 1129
Score = 31.6 bits (70), Expect = 3.0
Identities = 53/252 (21%), Positives = 87/252 (34%), Gaps = 17/252 (6%)
Query: 345 QPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGK-----MSHSSSGPASVSQLSS 399
QP + G+ + G + S ES + G + S S P+ + +
Sbjct: 1620 QPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPA 1679
Query: 400 WKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAA 459
+ P + +P +G+ PPP + + + G+ S + + GSP KRP
Sbjct: 1680 FVRPARVEPTDRDGGEAGESSAEPPP-SDMGTVGGQASHPQTLGARALGSPRKRP----- 1733
Query: 460 PAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRF 519
+PA ++ A + +S P V L +A P R
Sbjct: 1734 --EQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAP-SSPDVKLAVRR 1790
Query: 520 VKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSG---APAPAGISGSGLQ 576
+ A +I+V G + EGP V + PV +G A A +
Sbjct: 1791 AQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRA 1850
Query: 577 SSGGPLPDARPG 588
S GP +R G
Sbjct: 1851 GSLGPETPSRVG 1862
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 63.2 bits (152), Expect = 9e-10
Identities = 104/399 (26%), Positives = 148/399 (37%), Gaps = 40/399 (10%)
Query: 330 RPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQ-ESVQSKVKGPGKMSHSS 388
+P + Q+ P +P P P + +++S Q E ++S+ G GK
Sbjct: 202 KPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGK---PI 258
Query: 389 SGPASVSQLSSWKTPEQPDPVWVQSSVSG--KGEKHPPPRTQLPSSSG---KISSGNSFP 443
GP Q K P Q D Q+ + +GE P LPS S + + P
Sbjct: 259 QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP---SLPSPSKPPIQQPTPGKPP 315
Query: 444 PQQAGSPLKRPFPAAAPAVAAAAPAPAPA------PAAAPALAAAAVAAAAGGAAP---- 493
QQ G +P PA PA + P P P A G A P
Sbjct: 316 AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQ 375
Query: 494 SHSQKPSV--PLIKASRRRPAAGR-PTRFVKIA--PAIQVRTGSTGLKATNVEGPVRGAQ 548
+ S+KPS P KA + P G+ P + A P QV T + ++ P A+
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP---AK 432
Query: 549 VLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQA-SSPAPLQFFLNTPEG 607
G + PVQ PG G PA +G G S+ P P + + P P Q P
Sbjct: 433 APGPTKTPVQQPGPGK-IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491
Query: 608 LRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPP--QPGPQGSTLGLSTQGQAF 665
+P + + P T P Q QQP + PP QPG + + +
Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSP-QQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550
Query: 666 PAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGV 704
Q V+ TG+G LQP + + Q P QG+
Sbjct: 551 AQQSTKPVSQTGSGKPLQPPTVSP-----SAKQPPSQGL 584
Score = 43.1 bits (100), Expect = 0.001
Identities = 108/461 (23%), Positives = 151/461 (32%), Gaps = 79/461 (17%)
Query: 380 GPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSG--KGEKHPPPRTQLPSSSGKIS 437
G G SH++ + LS E+ V S G KG PP + PS K
Sbjct: 28 GAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSV-PPAAAESPSMHRKQE 86
Query: 438 SGNSFPPQQAGSPLKRPFPAAAPAVAAAAP-----APAPAPAAAPALAAAAVAAAAGGAA 492
+S PP+Q+G P P A P ++ + + P +P+ + + +
Sbjct: 87 LDSSHPPKQSGRP-PDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLK 145
Query: 493 PSHSQKPSVPLIKASRRRPAAG------RPTRFVKIAPAIQVRTGSTGLKATNVEGPVRG 546
H + A P + + A Q T +G G
Sbjct: 146 EEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEG 205
Query: 547 AQVLGCSFKP--VQAPGSGAPAPAGISGSGLQSSGGP--LPDARPGAVQASSPA---PLQ 599
KP Q P P G LQ G P + +P +++ P P+Q
Sbjct: 206 I------IKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQ 259
Query: 600 FFLNTP-----------EGLRPLTLQ--VPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHP 646
TP + RP T Q + +G +V + S S +QQPT P
Sbjct: 260 GPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV-----KPSLPSPSKPPIQQPTPGKP 314
Query: 647 P--QPGPQGSTLG-----LSTQGQAFP-AQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQ 698
P QPG + S G G P AQQ V G P LG A+
Sbjct: 315 PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP----LGPAK 370
Query: 699 VPQQGVQLPFVLGQQPQPLLLLQP---------QPQPQQIQLQT--QPLRVLQQPVFLAT 747
P Q +QP P L QP QP P + Q P + QQP +
Sbjct: 371 PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP 430
Query: 748 G------AVQIVQPHPG----VQAGSQLVGQRKGGKPTPPA 778
+ QP PG QAG ++ G PP+
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471
Score = 42.0 bits (97), Expect = 0.002
Identities = 50/192 (26%), Positives = 73/192 (38%), Gaps = 23/192 (11%)
Query: 328 KIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHS 387
K P+K + S K +P P PG AG+ V Q+S + P + S
Sbjct: 852 KEEPKKAQTKMSPKPDAKPMPKGSPT--PPGPRPTAGQTVPTPQQSPK-----PQEQSRR 904
Query: 388 SSGPASVSQLSSWKTPEQPDPVWVQSSVSGK----GEKHPPPRTQLPSSSGK----ISSG 439
S L S + P Q +V+GK G + L S++G+ SG
Sbjct: 905 FS-----LNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSG 959
Query: 440 NSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKP 499
P +QA +P + P P AP PAPA + + A AA P Q P
Sbjct: 960 PGAPMKQAPAPSQPPTSQGPPKSTGQAP---PAPAKSIPVKKETKAPAAEKLEPKAEQAP 1016
Query: 500 SVPLIKASRRRP 511
+V + ++ P
Sbjct: 1017 TVKRTETEKKPP 1028
Score = 41.6 bits (96), Expect = 0.003
Identities = 79/353 (22%), Positives = 127/353 (35%), Gaps = 56/353 (15%)
Query: 190 QKMNTDPMEQCLQRYSWPSVKPQQEQSDC------------PPPPELRVSTSGQKEERKV 237
Q TD + LQR + +PQ +Q+D P P ++ T G+ ++
Sbjct: 263 QTPQTDHAKLPLQR---DASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQP 319
Query: 238 GQPCELNITKAGSCVDTWKGRPCDLAVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVED 297
G K +P P++ Q T P P +
Sbjct: 320 GHE---------------KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ 364
Query: 298 PFRHAWEAGCQAWDTKPNIMQSFNDPLLCGKIRPRKKARQKSQ-KSPWQPFPDDHSACLR 356
P A Q KP+ Q L + A+Q K P Q +
Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424
Query: 357 PGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVS 416
PG ++ A +A + VQ GPGK+ +GP S +Q P S +
Sbjct: 425 PGLQSPA-KAPGPTKTPVQQP--GPGKIPAQQAGPGKTSA-------QQTGPTKPPSQLP 474
Query: 417 GKGEKHPPPRTQLPSSSGKISSGNSFPP-QQAGS---PLKRPFPA-AAPAVAAAAPAPAP 471
G + PPP+ P+ G++ PP QQ GS P ++P PA +P + P+
Sbjct: 475 GPAK--PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Query: 472 APAAA------PALAAAAVAAAAGGAAPSHSQKPSVP--LIKASRRRPAAGRP 516
P +A P+ A + + + + S KP P + ++++ P+ G P
Sbjct: 533 QPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585
Score = 39.3 bits (90), Expect = 0.014
Identities = 74/363 (20%), Positives = 123/363 (33%), Gaps = 61/363 (16%)
Query: 354 CLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQS 413
CL + G ++ S Q K+K + S+ S S +T + D Q
Sbjct: 637 CLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA---VSKSSPQPQQTSPKKDAAPKQD 693
Query: 414 SVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAA-------AA 466
K PPP + P+ G S+ PP+ L +P P P+V + A
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE--ADSLSKPAPPKEPSVPSEQDKAPVAD 751
Query: 467 PAPAPAPAAAPALAAAAVAAAA------GGAAPSHSQKPSVPLIKASRRRPAAGRPTRFV 520
P P + ++A S +++ + P +K +P+ P
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE 811
Query: 521 KIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGA--PAPAGISGSGLQSS 578
K++P + + P ++++ ++ G P Q+
Sbjct: 812 KVSP----------FDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTK 861
Query: 579 GGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQL-VSLQQ 637
P PDA+P + SP TP G RP Q PQ+QS + ++L
Sbjct: 862 MSPKPDAKP--MPKGSP--------TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGS 911
Query: 638 LQQPTAAHP--PQPGPQGSTLG------------LSTQGQAFPAQQLLNVNLTGAGSGLQ 683
+ + P PQ G G +ST GQ P Q +G G+ ++
Sbjct: 912 ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ------SGPGAPMK 965
Query: 684 PQP 686
P
Sbjct: 966 QAP 968
Score = 32.7 bits (73), Expect = 1.3
Identities = 57/267 (21%), Positives = 88/267 (32%), Gaps = 35/267 (13%)
Query: 334 KARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPAS 393
K +Q P SA +P + + + SQA+E +K S S P +
Sbjct: 753 KPKQPKMVKPTTDLVSSSSATTKP--DIPSSKVQSQAEEKTTPPLK-TDSAKPSQSFPPT 809
Query: 394 VSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKR 453
++S + + P P +S HP P ++ P++A + +
Sbjct: 810 GEKVSPFDSKAIPRPASDSKIIS-----HPGPSSESKGQKQVDPVQKKEEPKKAQTKMS- 863
Query: 454 PFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAA 513
P P A P + P P P A G P+ Q P P ++ R
Sbjct: 864 PKPDAKPMPKGSPTPPGPRPTA-------------GQTVPTPQQSPK-PQEQSRRFSLNL 909
Query: 514 GRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGS 573
G T K P T + L GA + + + +G P P SG
Sbjct: 910 GSITDAPKSQPTTPQETVTGKLFGF-------GASIFSQASNLIST--AGQPGPHSQSGP 960
Query: 574 GLQSSGGPLPDARP---GAVQASSPAP 597
G P P P G +++ AP
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAP 987
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 63.2 bits (152), Expect = 9e-10
Identities = 104/399 (26%), Positives = 148/399 (37%), Gaps = 40/399 (10%)
Query: 330 RPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQ-ESVQSKVKGPGKMSHSS 388
+P + Q+ P +P P P + +++S Q E ++S+ G GK
Sbjct: 202 KPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGK---PI 258
Query: 389 SGPASVSQLSSWKTPEQPDPVWVQSSVSG--KGEKHPPPRTQLPSSSG---KISSGNSFP 443
GP Q K P Q D Q+ + +GE P LPS S + + P
Sbjct: 259 QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP---SLPSPSKPPIQQPTPGKPP 315
Query: 444 PQQAGSPLKRPFPAAAPAVAAAAPAPAPA------PAAAPALAAAAVAAAAGGAAP---- 493
QQ G +P PA PA + P P P A G A P
Sbjct: 316 AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQ 375
Query: 494 SHSQKPSV--PLIKASRRRPAAGR-PTRFVKIA--PAIQVRTGSTGLKATNVEGPVRGAQ 548
+ S+KPS P KA + P G+ P + A P QV T + ++ P A+
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP---AK 432
Query: 549 VLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQA-SSPAPLQFFLNTPEG 607
G + PVQ PG G PA +G G S+ P P + + P P Q P
Sbjct: 433 APGPTKTPVQQPGPGK-IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491
Query: 608 LRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPP--QPGPQGSTLGLSTQGQAF 665
+P + + P T P Q QQP + PP QPG + + +
Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSP-QQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550
Query: 666 PAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGV 704
Q V+ TG+G LQP + + Q P QG+
Sbjct: 551 AQQSTKPVSQTGSGKPLQPPTVSP-----SAKQPPSQGL 584
Score = 43.1 bits (100), Expect = 0.001
Identities = 108/461 (23%), Positives = 151/461 (32%), Gaps = 79/461 (17%)
Query: 380 GPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSG--KGEKHPPPRTQLPSSSGKIS 437
G G SH++ + LS E+ V S G KG PP + PS K
Sbjct: 28 GAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSV-PPAAAESPSMHRKQE 86
Query: 438 SGNSFPPQQAGSPLKRPFPAAAPAVAAAAP-----APAPAPAAAPALAAAAVAAAAGGAA 492
+S PP+Q+G P P A P ++ + + P +P+ + + +
Sbjct: 87 LDSSHPPKQSGRP-PDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLK 145
Query: 493 PSHSQKPSVPLIKASRRRPAAG------RPTRFVKIAPAIQVRTGSTGLKATNVEGPVRG 546
H + A P + + A Q T +G G
Sbjct: 146 EEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEG 205
Query: 547 AQVLGCSFKP--VQAPGSGAPAPAGISGSGLQSSGGP--LPDARPGAVQASSPA---PLQ 599
KP Q P P G LQ G P + +P +++ P P+Q
Sbjct: 206 I------IKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQ 259
Query: 600 FFLNTP-----------EGLRPLTLQ--VPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHP 646
TP + RP T Q + +G +V + S S +QQPT P
Sbjct: 260 GPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV-----KPSLPSPSKPPIQQPTPGKP 314
Query: 647 P--QPGPQGSTLG-----LSTQGQAFP-AQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQ 698
P QPG + S G G P AQQ V G P LG A+
Sbjct: 315 PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP----LGPAK 370
Query: 699 VPQQGVQLPFVLGQQPQPLLLLQP---------QPQPQQIQLQT--QPLRVLQQPVFLAT 747
P Q +QP P L QP QP P + Q P + QQP +
Sbjct: 371 PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP 430
Query: 748 G------AVQIVQPHPG----VQAGSQLVGQRKGGKPTPPA 778
+ QP PG QAG ++ G PP+
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471
Score = 42.0 bits (97), Expect = 0.002
Identities = 50/192 (26%), Positives = 73/192 (38%), Gaps = 23/192 (11%)
Query: 328 KIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHS 387
K P+K + S K +P P PG AG+ V Q+S + P + S
Sbjct: 852 KEEPKKAQTKMSPKPDAKPMPKGSPT--PPGPRPTAGQTVPTPQQSPK-----PQEQSRR 904
Query: 388 SSGPASVSQLSSWKTPEQPDPVWVQSSVSGK----GEKHPPPRTQLPSSSGK----ISSG 439
S L S + P Q +V+GK G + L S++G+ SG
Sbjct: 905 FS-----LNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSG 959
Query: 440 NSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKP 499
P +QA +P + P P AP PAPA + + A AA P Q P
Sbjct: 960 PGAPMKQAPAPSQPPTSQGPPKSTGQAP---PAPAKSIPVKKETKAPAAEKLEPKAEQAP 1016
Query: 500 SVPLIKASRRRP 511
+V + ++ P
Sbjct: 1017 TVKRTETEKKPP 1028
Score = 41.6 bits (96), Expect = 0.003
Identities = 79/353 (22%), Positives = 127/353 (35%), Gaps = 56/353 (15%)
Query: 190 QKMNTDPMEQCLQRYSWPSVKPQQEQSDC------------PPPPELRVSTSGQKEERKV 237
Q TD + LQR + +PQ +Q+D P P ++ T G+ ++
Sbjct: 263 QTPQTDHAKLPLQR---DASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQP 319
Query: 238 GQPCELNITKAGSCVDTWKGRPCDLAVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVED 297
G K +P P++ Q T P P +
Sbjct: 320 GHE---------------KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ 364
Query: 298 PFRHAWEAGCQAWDTKPNIMQSFNDPLLCGKIRPRKKARQKSQ-KSPWQPFPDDHSACLR 356
P A Q KP+ Q L + A+Q K P Q +
Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424
Query: 357 PGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVS 416
PG ++ A +A + VQ GPGK+ +GP S +Q P S +
Sbjct: 425 PGLQSPA-KAPGPTKTPVQQP--GPGKIPAQQAGPGKTSA-------QQTGPTKPPSQLP 474
Query: 417 GKGEKHPPPRTQLPSSSGKISSGNSFPP-QQAGS---PLKRPFPA-AAPAVAAAAPAPAP 471
G + PPP+ P+ G++ PP QQ GS P ++P PA +P + P+
Sbjct: 475 GPAK--PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Query: 472 APAAA------PALAAAAVAAAAGGAAPSHSQKPSVP--LIKASRRRPAAGRP 516
P +A P+ A + + + + S KP P + ++++ P+ G P
Sbjct: 533 QPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585
Score = 39.3 bits (90), Expect = 0.014
Identities = 74/363 (20%), Positives = 123/363 (33%), Gaps = 61/363 (16%)
Query: 354 CLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQS 413
CL + G ++ S Q K+K + S+ S S +T + D Q
Sbjct: 637 CLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA---VSKSSPQPQQTSPKKDAAPKQD 693
Query: 414 SVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAA-------AA 466
K PPP + P+ G S+ PP+ L +P P P+V + A
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE--ADSLSKPAPPKEPSVPSEQDKAPVAD 751
Query: 467 PAPAPAPAAAPALAAAAVAAAA------GGAAPSHSQKPSVPLIKASRRRPAAGRPTRFV 520
P P + ++A S +++ + P +K +P+ P
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE 811
Query: 521 KIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGA--PAPAGISGSGLQSS 578
K++P + + P ++++ ++ G P Q+
Sbjct: 812 KVSP----------FDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTK 861
Query: 579 GGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQL-VSLQQ 637
P PDA+P + SP TP G RP Q PQ+QS + ++L
Sbjct: 862 MSPKPDAKP--MPKGSP--------TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGS 911
Query: 638 LQQPTAAHP--PQPGPQGSTLG------------LSTQGQAFPAQQLLNVNLTGAGSGLQ 683
+ + P PQ G G +ST GQ P Q +G G+ ++
Sbjct: 912 ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ------SGPGAPMK 965
Query: 684 PQP 686
P
Sbjct: 966 QAP 968
Score = 32.7 bits (73), Expect = 1.3
Identities = 57/267 (21%), Positives = 88/267 (32%), Gaps = 35/267 (13%)
Query: 334 KARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPAS 393
K +Q P SA +P + + + SQA+E +K S S P +
Sbjct: 753 KPKQPKMVKPTTDLVSSSSATTKP--DIPSSKVQSQAEEKTTPPLK-TDSAKPSQSFPPT 809
Query: 394 VSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKR 453
++S + + P P +S HP P ++ P++A + +
Sbjct: 810 GEKVSPFDSKAIPRPASDSKIIS-----HPGPSSESKGQKQVDPVQKKEEPKKAQTKMS- 863
Query: 454 PFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAA 513
P P A P + P P P A G P+ Q P P ++ R
Sbjct: 864 PKPDAKPMPKGSPTPPGPRPTA-------------GQTVPTPQQSPK-PQEQSRRFSLNL 909
Query: 514 GRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGS 573
G T K P T + L GA + + + +G P P SG
Sbjct: 910 GSITDAPKSQPTTPQETVTGKLFGF-------GASIFSQASNLIST--AGQPGPHSQSGP 960
Query: 574 GLQSSGGPLPDARP---GAVQASSPAP 597
G P P P G +++ AP
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAP 987
>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
Length = 780
Score = 62.0 bits (149), Expect = 2e-09
Identities = 116/429 (27%), Positives = 153/429 (35%), Gaps = 88/429 (20%)
Query: 351 HSACLRPGSETDAGR-AVSQAQESVQSKVKGP-GKMSHSSSGPASVSQLSSWKTPEQPDP 408
HS+ +E D+G A + V + ++G G S + S +VSQL + QP P
Sbjct: 204 HSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTP 263
Query: 409 VWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAA----PAVAA 464
QS G+ + PPP G ++ Q+ +PL PFP AA P +AA
Sbjct: 264 AQPQSFSVGQPQPPPPP------VGGAVA--------QSSAPLP-PFPGAATGPQPMMAA 308
Query: 465 AAPA-PAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSV-PLIKASRRRPAAGRPTRFVKI 522
A P+ P A L V A P+ S P P + A PAA +P +F
Sbjct: 309 AQPSQPQGAGPGGQTLPPTNVTLAQ----PAMSLPPQPGPAVGA----PAAQQPQQFAYP 360
Query: 523 APAIQVR-------TGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGL 575
P I +G + +V G + S +P + A P G +G
Sbjct: 361 QPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVG-TGQNA 419
Query: 576 QSSGGPLPDA----------RPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAV--LT 623
S G L A R G Q AP Q P G+ P T+ G V
Sbjct: 420 SSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQ-----PTGVPPATV----GGVVQPCL 470
Query: 624 GPQQQSHQLVSLQQLQQPTAAHPPQPG-----------PQGSTLGLSTQGQAFPAQQLLN 672
GP QP + PPQ G P G+ A PA + +
Sbjct: 471 GPAGAG----------QPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPS 520
Query: 673 VNLTGAGSGLQPQPQAAVLSLLGSAQVPQ-----QGVQLPFVLGQQPQPLLLLQPQPQPQ 727
V+ T P P A L V + Q V LP G P L PQ
Sbjct: 521 VSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSL--PQSDLS 578
Query: 728 QIQLQTQPL 736
Q Q QTQPL
Sbjct: 579 QFQTQTQPL 587
Score = 57.4 bits (137), Expect = 5e-08
Identities = 109/467 (23%), Positives = 159/467 (34%), Gaps = 67/467 (14%)
Query: 348 PDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPD 407
P +C + S T A A S +++ + SS VS+ + + E +
Sbjct: 5 PAKKKSCFQITSVTTAQVATSITEDTESLDDPDESRTEDVSSEIFDVSRATDYGPEEVCE 64
Query: 408 PVWVQSSVSGKGEKHPPPRTQLPSS--SGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAA 465
+ +++ G+ P T P+ G++++ + P G R A + AA
Sbjct: 65 RSSSEETLNNVGDAETPG-TVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAA 123
Query: 466 APAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIA-- 523
A APAP A A +A AAPS + + +G P R +
Sbjct: 124 AATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCM 183
Query: 524 --------PAIQVRTGSTGLKATNVEGPVR---GAQVLGCSFKPVQAPGSGAPAPAGISG 572
++ R+G ++ + G G S V A GA P +
Sbjct: 184 EYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTD 243
Query: 573 SGLQ----------------------SSGGPLPDARP-GAVQASSPAPLQFFLNTPEGLR 609
S L S G P P P G A S APL F G +
Sbjct: 244 SSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQ 303
Query: 610 PLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQ-GSTLGLSTQGQAFPAQ 668
P+ GP Q+ ++ L QP + PPQPGP G+ Q A+P
Sbjct: 304 PMMAAAQPSQPQGAGPGGQTLPPTNV-TLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP 362
Query: 669 Q-----LLNVNLTGAG-------SGLQPQPQAAVLSLLGSAQVPQQGVQLPF-------- 708
Q LL V +G +GLQP P A S G+A P LP
Sbjct: 363 QIPPGHLLPVQPSGQSEYLQQHVAGLQP-PSPAQPSSTGAAASPATAATLPVGTGQNASS 421
Query: 709 ----VLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQ 751
++G QP + P+ P Q Q P + P G VQ
Sbjct: 422 VGAQLMGASSQPSEAMAPRTGPAQ-GGQVAPCQPTGVPPATVGGVVQ 467
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 61.6 bits (148), Expect = 3e-09
Identities = 116/460 (25%), Positives = 151/460 (32%), Gaps = 76/460 (16%)
Query: 333 KKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQ------SKVKGPGKMSH 386
KK+ +K ++ P + + S+T+ S + Q S +G G+ S
Sbjct: 76 KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSD 135
Query: 387 S-------SSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKH----PPPRTQLPSSSGK 435
S SS P + Q + +P P P +S ++ PP Q P+ G
Sbjct: 136 SRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT--GV 193
Query: 436 ISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSH 495
+ +S PP P P P+A +P + AP A A A H
Sbjct: 194 TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 253
Query: 496 SQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFK 555
Q+P P P P +Q TGS G Q S
Sbjct: 254 PQRPPSP------------HPPPHPSPHPPLQPLTGSAG-------------QPSAPSHA 288
Query: 556 PVQAPGSGAPAPAGI-SGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLT-L 613
G G P P + +G LQ G P P P + APL +P P T L
Sbjct: 289 QPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQA-SQGQAPLG---TSPAAAYPHTSL 344
Query: 614 QVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQ------PGPQGSTLGLSTQGQAFPA 667
Q+P + L Q Q + L P PP P PQ G P+
Sbjct: 345 QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG---PS 401
Query: 668 QQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQ 727
+N N L P P LS L S P P L Q QPL QP P
Sbjct: 402 PFSMNAN-------LPPPPALKPLSSL-STHHPPSAHPPPLQLMPQSQPLPSSPAQP-PG 452
Query: 728 QIQLQTQPLRVLQQPVFLATGAVQIV-QP----HPGVQAG 762
Q Q P P TG Q+ QP HP V G
Sbjct: 453 LTQSQNLPPPPASHP---PTGLHQVAPQPPFAQHPFVPGG 489
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 61.6 bits (148), Expect = 3e-09
Identities = 116/460 (25%), Positives = 151/460 (32%), Gaps = 76/460 (16%)
Query: 333 KKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQ------SKVKGPGKMSH 386
KK+ +K ++ P + + S+T+ S + Q S +G G+ S
Sbjct: 630 KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSD 689
Query: 387 S-------SSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKH----PPPRTQLPSSSGK 435
S SS P + Q + +P P P +S ++ PP Q P+ G
Sbjct: 690 SRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT--GV 747
Query: 436 ISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSH 495
+ +S PP P P P+A +P + AP A A A H
Sbjct: 748 TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 807
Query: 496 SQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFK 555
Q+P P P P +Q TGS G Q S
Sbjct: 808 PQRPPSP------------HPPPHPSPHPPLQPLTGSAG-------------QPSAPSHA 842
Query: 556 PVQAPGSGAPAPAGI-SGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLT-L 613
G G P P + +G LQ G P P P + APL +P P T L
Sbjct: 843 QPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQA-SQGQAPLG---TSPAAAYPHTSL 898
Query: 614 QVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQ------PGPQGSTLGLSTQGQAFPA 667
Q+P + L Q Q + L P PP P PQ G P+
Sbjct: 899 QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG---PS 955
Query: 668 QQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQ 727
+N N L P P LS L S P P L Q QPL QP P
Sbjct: 956 PFSMNAN-------LPPPPALKPLSSL-STHHPPSAHPPPLQLMPQSQPLPSSPAQP-PG 1006
Query: 728 QIQLQTQPLRVLQQPVFLATGAVQIV-QP----HPGVQAG 762
Q Q P P TG Q+ QP HP V G
Sbjct: 1007 LTQSQNLPPPPASHP---PTGLHQVAPQPPFAQHPFVPGG 1043
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 61.6 bits (148), Expect = 3e-09
Identities = 116/460 (25%), Positives = 151/460 (32%), Gaps = 76/460 (16%)
Query: 333 KKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQ------SKVKGPGKMSH 386
KK+ +K ++ P + + S+T+ S + Q S +G G+ S
Sbjct: 630 KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSD 689
Query: 387 S-------SSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKH----PPPRTQLPSSSGK 435
S SS P + Q + +P P P +S ++ PP Q P+ G
Sbjct: 690 SRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT--GV 747
Query: 436 ISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSH 495
+ +S PP P P P+A +P + AP A A A H
Sbjct: 748 TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 807
Query: 496 SQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFK 555
Q+P P P P +Q TGS G Q S
Sbjct: 808 PQRPPSP------------HPPPHPSPHPPLQPLTGSAG-------------QPSAPSHA 842
Query: 556 PVQAPGSGAPAPAGI-SGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLT-L 613
G G P P + +G LQ G P P P + APL +P P T L
Sbjct: 843 QPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQA-SQGQAPLG---TSPAAAYPHTSL 898
Query: 614 QVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQ------PGPQGSTLGLSTQGQAFPA 667
Q+P + L Q Q + L P PP P PQ G P+
Sbjct: 899 QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG---PS 955
Query: 668 QQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQ 727
+N N L P P LS L S P P L Q QPL QP P
Sbjct: 956 PFSMNAN-------LPPPPALKPLSSL-STHHPPSAHPPPLQLMPQSQPLPSSPAQP-PG 1006
Query: 728 QIQLQTQPLRVLQQPVFLATGAVQIV-QP----HPGVQAG 762
Q Q P P TG Q+ QP HP V G
Sbjct: 1007 LTQSQNLPPPPASHP---PTGLHQVAPQPPFAQHPFVPGG 1043
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 60.8 bits (146), Expect = 5e-09
Identities = 90/325 (27%), Positives = 115/325 (35%), Gaps = 39/325 (12%)
Query: 468 APAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQ 527
+P PA P A+ A A A P+ A R+RP AG+ I P
Sbjct: 327 SPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILP--- 383
Query: 528 VRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARP 587
++ T K V+ P + A G S +P P P L + P A P
Sbjct: 384 IQPALTPRKRATVQPPPQAA---GSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPP 440
Query: 588 GAVQASS------PAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQ---L 638
Q S PA Q TP+ + L L+ Q QQQ QQ
Sbjct: 441 TPQQTPSTQAQGLPAQAQA---TPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQT 497
Query: 639 QQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQ 698
QQ A HP P + + +QG + QQL+ Q Q Q + + L Q
Sbjct: 498 QQFQAVHPATQQPAIAQFPVVSQGGS--QQQLMQNFYQQQQQQQQQQQQQQLATALHQQQ 555
Query: 699 VPQQGVQLP----FVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQ 754
+ Q L GQQPQP PQP P Q P+R QQP T
Sbjct: 556 LMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVR--QQPKVQTT------- 606
Query: 755 PHPGVQAGSQLVGQRKGGKPTPPAP 779
P P VQ GQ+ G P +P
Sbjct: 607 PPPAVQ------GQKVGSLTPPSSP 625
Score = 31.2 bits (69), Expect = 3.9
Identities = 31/127 (24%), Positives = 47/127 (37%), Gaps = 17/127 (13%)
Query: 436 ISSGNSFPPQQAGSPLKRPFPAAAPAVAAAA-PAPAPAPAAAPALAAAAVAAAAGGAAP- 493
+++G PQ A +P +P PA PA+ A P PA+ V + ++P
Sbjct: 569 MAAGQQPQPQPAAAP--QPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPK 626
Query: 494 -------------SHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNV 540
+HS VP K+++ AA K A +GS NV
Sbjct: 627 TQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQQNV 686
Query: 541 EGPVRGA 547
P G+
Sbjct: 687 YNPSEGS 693
Score = 30.0 bits (66), Expect = 8.6
Identities = 30/153 (19%), Positives = 56/153 (36%), Gaps = 6/153 (3%)
Query: 346 PFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQ 405
P P+ ++ + P + +A A + Q K + + + + A + + +T
Sbjct: 320 PIPNVQNSPI-PAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPN 378
Query: 406 PDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAA 465
P + +Q +++ + P Q SS + S P + +P +P P A
Sbjct: 379 PGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQA 438
Query: 466 APAPAPAPAAAPALAAAAVAAAAGGAAPSHSQK 498
P P P+ A A A P H Q+
Sbjct: 439 PPTPQQTPS-----TQAQGLPAQAQATPQHQQQ 466
>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 59.7 bits (143), Expect = 1e-08
Identities = 67/244 (27%), Positives = 92/244 (37%), Gaps = 40/244 (16%)
Query: 378 VKGPGKMS----HSSSGPA---SVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLP 430
++GPG++ S S PA Q+ + P PV V +VS PP
Sbjct: 60 LRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVS------PPLEPAAE 113
Query: 431 SSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGG 490
S G + P +P P P V A APAPAPAP AAP A AVA A
Sbjct: 114 SLDGLEEAPEQLPSVPVPAPASTPPPVP---VLAPAPAPAPAPVAAPVAAPVAVAVLAPA 170
Query: 491 AAPSHSQKPSVPLIKASRRRPA-----AGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVR 545
AP+ + P+ + A PA A P AP G+ + + P+
Sbjct: 171 PAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGAN--QGQRGQEPLA 228
Query: 546 GAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPL------------PDARPGAVQAS 593
G S +P + A A +G+ ++ GPL P+ G V A
Sbjct: 229 DQLHSGISGRP-----AAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAP 283
Query: 594 SPAP 597
P+P
Sbjct: 284 CPSP 287
>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 59.7 bits (143), Expect = 1e-08
Identities = 67/244 (27%), Positives = 92/244 (37%), Gaps = 40/244 (16%)
Query: 378 VKGPGKMS----HSSSGPA---SVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLP 430
++GPG++ S S PA Q+ + P PV V +VS PP
Sbjct: 60 LRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVS------PPLEPAAE 113
Query: 431 SSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGG 490
S G + P +P P P V A APAPAPAP AAP A AVA A
Sbjct: 114 SLDGLEEAPEQLPSVPVPAPASTPPPVP---VLAPAPAPAPAPVAAPVAAPVAVAVLAPA 170
Query: 491 AAPSHSQKPSVPLIKASRRRPA-----AGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVR 545
AP+ + P+ + A PA A P AP G+ + + P+
Sbjct: 171 PAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGAN--QGQRGQEPLA 228
Query: 546 GAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPL------------PDARPGAVQAS 593
G S +P + A A +G+ ++ GPL P+ G V A
Sbjct: 229 DQLHSGISGRP-----AAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAP 283
Query: 594 SPAP 597
P+P
Sbjct: 284 CPSP 287
>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
sapiens]
Length = 316
Score = 59.7 bits (143), Expect = 1e-08
Identities = 67/244 (27%), Positives = 92/244 (37%), Gaps = 40/244 (16%)
Query: 378 VKGPGKMS----HSSSGPA---SVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLP 430
++GPG++ S S PA Q+ + P PV V +VS PP
Sbjct: 71 LRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVS------PPLEPAAE 124
Query: 431 SSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGG 490
S G + P +P P P V A APAPAPAP AAP A AVA A
Sbjct: 125 SLDGLEEAPEQLPSVPVPAPASTPPPVP---VLAPAPAPAPAPVAAPVAAPVAVAVLAPA 181
Query: 491 AAPSHSQKPSVPLIKASRRRPA-----AGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVR 545
AP+ + P+ + A PA A P AP G+ + + P+
Sbjct: 182 PAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGAN--QGQRGQEPLA 239
Query: 546 GAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPL------------PDARPGAVQAS 593
G S +P + A A +G+ ++ GPL P+ G V A
Sbjct: 240 DQLHSGISGRP-----AAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAP 294
Query: 594 SPAP 597
P+P
Sbjct: 295 CPSP 298
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 59.3 bits (142), Expect = 1e-08
Identities = 107/443 (24%), Positives = 150/443 (33%), Gaps = 75/443 (16%)
Query: 366 AVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPP 425
A S +QES+ ++ +G G HS PA P P SG G+ PP
Sbjct: 611 ARSPSQESIGARSRGSG---HSQEQPA-------------PQP-------SG-GDPSPPQ 646
Query: 426 RTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVA 485
LP + + S P Q P +P +P ++PAP P P A A +
Sbjct: 647 ERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSP----SSPAPGPPPGAPWAFS----Y 698
Query: 486 AAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGST-GLKATNVEGPV 544
A A P +P SR P G + GST G AT P
Sbjct: 699 LAGPPATPPDPPRPKRRSHSLSRPGPTEG------DAEGEAEGPVGSTLGSYATLTRRPG 752
Query: 545 RGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASS--PAPLQFFL 602
R A ++ S P G P + + P P R +V S P PL
Sbjct: 753 RSA-LVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESP 811
Query: 603 NTPEGL---RPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLS 659
EG R TL P G + GP + ++ + PP G G L +
Sbjct: 812 GPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFA 871
Query: 660 TQG---------------QAFPAQQLLNVNLTGAGSGLQPQP--------QAAVLSLLGS 696
+G + P L+ NLT + + ++ +P Q A+L+ +
Sbjct: 872 EEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDT-VKRRPKCREREPLQTALLAFGVA 930
Query: 697 AQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQPH 756
+ P LP + P L PQP+P + Q P + P V P
Sbjct: 931 SATPGPAAPLPSPTPGESPPASSL-PQPEPSSLPAQGVPTPLAPSPAMQPP-----VPPC 984
Query: 757 PGVQAGSQLVGQRKGGKPTPPAP 779
PG S + G P AP
Sbjct: 985 PGPGLESSAASRWNGETEPPAAP 1007
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 59.3 bits (142), Expect = 1e-08
Identities = 107/443 (24%), Positives = 150/443 (33%), Gaps = 75/443 (16%)
Query: 366 AVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPP 425
A S +QES+ ++ +G G HS PA P P SG G+ PP
Sbjct: 693 ARSPSQESIGARSRGSG---HSQEQPA-------------PQP-------SG-GDPSPPQ 728
Query: 426 RTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVA 485
LP + + S P Q P +P +P ++PAP P P A A +
Sbjct: 729 ERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSP----SSPAPGPPPGAPWAFS----Y 780
Query: 486 AAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGST-GLKATNVEGPV 544
A A P +P SR P G + GST G AT P
Sbjct: 781 LAGPPATPPDPPRPKRRSHSLSRPGPTEG------DAEGEAEGPVGSTLGSYATLTRRPG 834
Query: 545 RGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASS--PAPLQFFL 602
R A ++ S P G P + + P P R +V S P PL
Sbjct: 835 RSA-LVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESP 893
Query: 603 NTPEGL---RPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLS 659
EG R TL P G + GP + ++ + PP G G L +
Sbjct: 894 GPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFA 953
Query: 660 TQG---------------QAFPAQQLLNVNLTGAGSGLQPQP--------QAAVLSLLGS 696
+G + P L+ NLT + + ++ +P Q A+L+ +
Sbjct: 954 EEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDT-VKRRPKCREREPLQTALLAFGVA 1012
Query: 697 AQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQPH 756
+ P LP + P L PQP+P + Q P + P V P
Sbjct: 1013 SATPGPAAPLPSPTPGESPPASSL-PQPEPSSLPAQGVPTPLAPSPAMQPP-----VPPC 1066
Query: 757 PGVQAGSQLVGQRKGGKPTPPAP 779
PG S + G P AP
Sbjct: 1067 PGPGLESSAASRWNGETEPPAAP 1089
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 58.2 bits (139), Expect = 3e-08
Identities = 95/409 (23%), Positives = 141/409 (34%), Gaps = 53/409 (12%)
Query: 382 GKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNS 441
G H S PA V+ + + P PV V S + P T P+ + N
Sbjct: 1245 GGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSST-------PSTTPAPTGLSLPLAANQ 1297
Query: 442 FPPQQAGSP-------LKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPS 494
PP + + P P V APAP P + PA V P
Sbjct: 1298 VPPTMVNNTGVVKIVVRQAPRDGLTP-VPPLAPAPRPPSSGLPA-----VLNPRPTLTPG 1351
Query: 495 HSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVL-GCS 553
P++ +A P RP + +P+ +V + G + P+ L G +
Sbjct: 1352 RLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPA 1411
Query: 554 FKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTL 613
P+ P S +P + +S + LP + P + A + APL ++ P LT+
Sbjct: 1412 SSPMPIPNS-SPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAP-----LTV 1465
Query: 614 QVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGS-------TLGLSTQGQAFP 666
G A+LT +V P A PP P G+ TLGL+T
Sbjct: 1466 SA-SGPALLTSVTPPLAPVV-------PAAPGPPSLAPSGASPSASALTLGLATAPSLSS 1517
Query: 667 AQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPL---LLLQPQ 723
+Q + L S P + V VP + PF P P LL
Sbjct: 1518 SQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPAS 1577
Query: 724 PQPQQIQLQTQPLRVLQQPVFLATGA-----VQIVQPHPG---VQAGSQ 764
Q + P+ Q + + A + ++ P PG V A SQ
Sbjct: 1578 SASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQ 1626
Score = 54.3 bits (129), Expect = 4e-07
Identities = 96/419 (22%), Positives = 132/419 (31%), Gaps = 61/419 (14%)
Query: 355 LRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSS 414
L PG ++A + V+ K+ HS S S S + P+ V SS
Sbjct: 1348 LTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTIS-SPLHVPSS 1406
Query: 415 VSGKGEKHPPPRTQLP-----SSSGKISSGNSFP-------PQQAGSPLKRPF------- 455
+ G P P SS+ + +S P P A +PL P
Sbjct: 1407 LPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVS 1466
Query: 456 -----------PAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLI 504
P AP V AA P+ AP+ A A+A A + S SQ P PL+
Sbjct: 1467 ASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLL 1526
Query: 505 KASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPV-----------RGAQVLGCS 553
A G + + V + + P +Q L
Sbjct: 1527 LAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATP 1586
Query: 554 FKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTL 613
P+ AP + AP+ P P A P + +P P+ +TP
Sbjct: 1587 LAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASAS 1646
Query: 614 QVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGS-TLGLS-----TQGQAFPA 667
VP VL S Q P P P P + TL L+ T G + P+
Sbjct: 1647 PVPAPTPVLA---------PSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPS 1697
Query: 668 QQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQP 726
Q L G G+ P P + S+ VP L G P L P P
Sbjct: 1698 QTL----SLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAP 1752
Score = 53.9 bits (128), Expect = 6e-07
Identities = 102/406 (25%), Positives = 144/406 (35%), Gaps = 61/406 (15%)
Query: 380 GPGKMSHSSSGP---------ASVSQLSSWKTPEQPDPVWVQSS-VSGKGEKHPPPRTQL 429
GP ++ S + P A+ LSS +TP P + SS V G P + +
Sbjct: 1489 GPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPV 1548
Query: 430 PSSSGKISSGNSFP----PQQAGSPLKRPFPAAAPAVAAA-APAPAP-----APAAAPAL 479
+ ++S FP P A + L P +A+ A+A AP AP AP+ AP L
Sbjct: 1549 LVPASALAS--PFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPL 1606
Query: 480 AAAAVAAAAGGAAP--SHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKA 537
A V A + GAAP + SQ P + +S + + P + + T L A
Sbjct: 1607 APLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPA 1666
Query: 538 TNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASS--P 595
A + P AP G +P+ G + GP P ASS P
Sbjct: 1667 PVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVP 1726
Query: 596 APLQFFLNTP------------EGLRPLTLQVPQGWA----VLTGPQQQSHQLVSLQQLQ 639
P Q P PL P G A + P S L++ +Q
Sbjct: 1727 TPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQ 1786
Query: 640 QPTAAHPPQP--GPQGS-TLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGS 696
T + P P GP + TL L+ PA Q ++ V+S G+
Sbjct: 1787 TLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSL----------------VVSASGA 1830
Query: 697 AQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQP 742
A +P V V +P L L P P R +QP
Sbjct: 1831 APLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQP 1876
Score = 38.1 bits (87), Expect = 0.032
Identities = 38/143 (26%), Positives = 55/143 (38%), Gaps = 17/143 (11%)
Query: 363 AGRAVSQAQESV----QSKVKGPGKMSHSSSGPASVSQLSSWKT--PEQPDPVWVQSSVS 416
A + + QA+E V Q + +GPG SS G + S K PE+P +
Sbjct: 2342 ARKDLDQAKEEVFRLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRG 2401
Query: 417 GKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAA 476
+ E T P S + + PP+ + + + P PA P P P PA+A
Sbjct: 2402 ARAETQGANHT--PVISAHQTRSTTTPPRCSPARERVPRPA---------PRPRPTPASA 2450
Query: 477 PALAAAAVAAAAGGAAPSHSQKP 499
PA A V P + P
Sbjct: 2451 PAAIPALVPVPVSAPVPISAPNP 2473
Score = 35.8 bits (81), Expect = 0.16
Identities = 79/374 (21%), Positives = 125/374 (33%), Gaps = 76/374 (20%)
Query: 444 PQQAGSPLKRPFPAAAPAVAAAAPAPAPAP----AAAPALAAAAVAAAAGGAAPSHSQKP 499
P+ + P P P PA + +PA P + P G+ P P
Sbjct: 1030 PELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSP 1089
Query: 500 SVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQA 559
+ ++ + R P PT +K P VR P G+ L KP+
Sbjct: 1090 -LGVLSGTSRPPT---PTLSLKPTPPAPVRLS---------PAPPPGSSSL---LKPLTV 1133
Query: 560 PGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLN---------------- 603
P PA + + ++ A AV A +PAP + L+
Sbjct: 1134 PPGYTFPPAAATTTSTTTA-----TATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIG 1188
Query: 604 -----------TPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQ 652
G +PLT Q+ LTG Q ++QL A P+P +
Sbjct: 1189 QLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQ--------VRQL----AVGQPRPLQR 1236
Query: 653 GSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQ-PQPQAAVLSLLGSAQVPQQGVQLPFVLG 711
+S GQ Q +V L A + P P + + S S G+ LP
Sbjct: 1237 NVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAAN 1296
Query: 712 QQPQPL------LLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQPHPGVQAG--- 762
Q P + + + + P+ PL +P ++G ++ P P + G
Sbjct: 1297 QVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPP--SSGLPAVLNPRPTLTPGRLP 1354
Query: 763 SQLVGQRKGGKPTP 776
+ +G + PTP
Sbjct: 1355 TPTLGTARAPMPTP 1368
Score = 35.0 bits (79), Expect = 0.27
Identities = 70/277 (25%), Positives = 104/277 (37%), Gaps = 48/277 (17%)
Query: 425 PRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPA-VAAAAPAP--AP----APAAAP 477
P+ P+ + ++ +S P A + P P P + APAP AP PA A
Sbjct: 1707 PQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAH 1766
Query: 478 ALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKA 537
L A +++A AP+ Q ++ PAA + + +APA T S +A
Sbjct: 1767 TLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQT---LALAPA---STQSPASQA 1820
Query: 538 TNVEGPVRGA---QVLGCSFKPVQAP-------GSGAPAPAGISGSGLQSSGGPLPDARP 587
+++ GA V S PV SG P+P S S GGP P +P
Sbjct: 1821 SSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPP----STATSFGGPRPRRQP 1876
Query: 588 GAVQASSPAPLQFFLNTPEGLR--------PLTLQVPQGWAVLTGPQQQSHQLVSLQQLQ 639
P F+L++ E R Q+ + L +++ L
Sbjct: 1877 -----PPPPRSPFYLDSLEEKRKRQRSERLERIFQLSEAHGALA--PVYGTEVLDFCTLP 1929
Query: 640 QPTAA--HPPQPGPQGSTLGLSTQGQ----AFPAQQL 670
QP A+ P PGP T T+ FP Q+L
Sbjct: 1930 QPVASPIGPRSPGPSHPTFWTYTEAAHRAVLFPQQRL 1966
Score = 32.0 bits (71), Expect = 2.3
Identities = 48/239 (20%), Positives = 81/239 (33%), Gaps = 34/239 (14%)
Query: 219 PPPPELRVSTSG------QKEERKVGQPCELNITKAGSCVDTWKGRPCDLAVPSEVDVEK 272
PPPP R+ + EE + E+ + G+ + + L E+ +E+
Sbjct: 275 PPPPASRLDDEDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPLEE 334
Query: 273 LAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFNDPLLCGKIRPR 332
L + P P + R E G + + P +++ I+P
Sbjct: 335 LLRSLPPQLLEGPSSPSQTPSSHDSDTRDGPEEGAE--EEPPQVLE----------IKPP 382
Query: 333 KKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSH-SSSGP 391
A + K PW P DD D ++ A+E ++ +V ++S + G
Sbjct: 383 PSAVTQRNKQPWHPDEDDEEFTANEEEAEDEEDTIA-AEEQLEGEVDHAMELSELAREGE 441
Query: 392 ASVSQL-----------SSWKTPEQPDPVWVQSS---VSGKGEKHPPPRTQLPSSSGKI 436
S+ +L S E D V SS G E PP+ S S +
Sbjct: 442 LSMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSV 500
Score = 31.2 bits (69), Expect = 3.9
Identities = 46/158 (29%), Positives = 67/158 (42%), Gaps = 19/158 (12%)
Query: 630 HQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQ---LLNVNLTGAGSG---LQ 683
H+L L+ TA PP P P+ + ++ Q P Q+ ++ VN A G ++
Sbjct: 967 HRLSRRVLLEVATAPDPP-PRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVR 1025
Query: 684 PQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPV 743
P P + + VPQ VL P L++ P I P VL P+
Sbjct: 1026 PPPGPELSAQPTPGPVPQ-------VL---PASLMVSASPAGPPLIPASRPPGPVLLPPL 1075
Query: 744 FLATGAVQIVQPHP-GVQAG-SQLVGQRKGGKPTPPAP 779
+G++ V P P GV +G S+ KPTPPAP
Sbjct: 1076 QPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAP 1113
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 57.0 bits (136), Expect = 7e-08
Identities = 56/210 (26%), Positives = 70/210 (33%), Gaps = 37/210 (17%)
Query: 380 GPGKMSHSSS-GPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISS 438
GPG+ P Q P+QP P + PPP P
Sbjct: 50 GPGQSGPKPPIPPPPPHQQQQQPPPQQPPP------------QQPPPHQPPPHPQPHQQQ 97
Query: 439 GNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQK 498
PPQ + P+ P AP V +A PA + AP A P + A G P+ +
Sbjct: 98 QPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG---APPGSGPGPTPTPP 154
Query: 499 PSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQ 558
P+V + P A PT P + G V GP G P Q
Sbjct: 155 PAV-----TSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPG---------PKQ 200
Query: 559 APGSGAPAPAGISGSGLQSSGGPLPDARPG 588
PG G P G + GGP P PG
Sbjct: 201 GPGPGGP-------KGGKMPGGPKPGGGPG 223
Score = 38.9 bits (89), Expect = 0.018
Identities = 46/180 (25%), Positives = 51/180 (28%), Gaps = 18/180 (10%)
Query: 329 IRPRKKARQKSQKSPWQPFPDD---HSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMS 385
I P +Q+ Q P QP P H P S +GPG
Sbjct: 60 IPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAP 119
Query: 386 HSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKI---SSGNSF 442
S P + S P P S G PP T P + SSG
Sbjct: 120 GVGSAPPASSSAPPATPPTSGAP---PGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPT 176
Query: 443 PPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVP 502
P QAG P P AA P P P P P GG P S P
Sbjct: 177 TPPQAGGP---------PPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTP 227
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 56.6 bits (135), Expect = 9e-08
Identities = 79/297 (26%), Positives = 113/297 (38%), Gaps = 49/297 (16%)
Query: 372 ESVQSKVKGPGKMSHSSSGPASVS-QLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLP 430
++ Q + P + HS P V+ + + P P P + PP L
Sbjct: 219 DAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPA---------PPSVPTLI 269
Query: 431 SSSGKIS-SGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAG 489
S S +S S + P A +P P P +APA PAP P +AP LA + A
Sbjct: 270 SDSNPLSVSASVLVPVPASAPPSGPVPLSAPA-----PAPLSVPVSAPPLAL--IQAPVP 322
Query: 490 GAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQV 549
+AP+ P + A PA+ P + + T S+G +T P
Sbjct: 323 PSAPTLVLAPVPTPVLAPM--PASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIP------ 374
Query: 550 LGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNT---PE 606
+F P P AP PA I + P+P A P A+ S+P P F L+ P
Sbjct: 375 ---AFAPTPVP---APTPAPI----FTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPA 424
Query: 607 GLRPLTLQVP---QGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLST 660
P +VP Q VLT Q L + P+ P +TLG+S+
Sbjct: 425 AQAPAMQKVPLSFQPGTVLTPSQ-------PLVYIPPPSCGQPLSVATLPTTLGVSS 474
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 55.8 bits (133), Expect = 1e-07
Identities = 81/352 (23%), Positives = 123/352 (34%), Gaps = 48/352 (13%)
Query: 373 SVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSS 432
SV + K P S+ + LSS +P + + ++S+S +G K P T P+
Sbjct: 800 SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFL-PENSLSFQGSKDSPATTHSPTP 858
Query: 433 SGKISS------------GNSFPPQQAGSP--LKRPFPAAAPAVAAAAPAPAPAPAAAPA 478
+ G + PP++ +P + PFP PA PAP APA
Sbjct: 859 PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT--------PAPKQAPA 910
Query: 479 LAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKAT 538
L+ + + A P+ P+ P K + PAA P+ K PA + A
Sbjct: 911 LSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS--PKGGPATPSPKWAPTPPAA 968
Query: 539 NVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPL 598
P G P GAP P + + GGP + GA P P
Sbjct: 969 TPPSPKGG---------PATPSPKGAPTPP--AATPPSPKGGPATPSPKGA-----PTPP 1012
Query: 599 QFFLNTPEGLRPLTLQVPQGWA---VLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGST 655
+P+G P P+G + T P + + PT P P+G
Sbjct: 1013 AVTPPSPKG-SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071
Query: 656 LGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLP 707
S +G P + G P P+ A + + P+ G+ P
Sbjct: 1072 ATPSLKGAPTPPAA---TPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120
Score = 53.5 bits (127), Expect = 7e-07
Identities = 66/233 (28%), Positives = 82/233 (35%), Gaps = 28/233 (12%)
Query: 390 GPASVSQLSSWKTPEQ--PDPVWVQSSVSGKGEKHPPPRTQ---------LPSSSGKISS 438
GPA+ S + P P P ++ S KG PP T P G +
Sbjct: 976 GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035
Query: 439 GNSFPPQQAGSPLKRPFPAAAPAV-AAAAPAPAPAPA-----AAPALAAAAVAAAAGG-A 491
+ PP GSP P P AP AA P+P PA AP AA + GG A
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA 1095
Query: 492 APSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLG 551
PS P P A+ P G T K AP T + K P +GA
Sbjct: 1096 TPSPKGAPMPP--AATPPSPKGGLATPPHKGAPTTPAATPPSP-KGGLATPPPKGAPTTP 1152
Query: 552 CSFKPVQAPGSGAPAPAGI----SGSGLQSSGG---PLPDARPGAVQASSPAP 597
+ P G P P G + + GG P P P A+ P+P
Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1205
Score = 51.2 bits (121), Expect = 4e-06
Identities = 108/447 (24%), Positives = 139/447 (31%), Gaps = 77/447 (17%)
Query: 379 KGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISS 438
+GP + + S++ S K P P + +S S KG PP T G +
Sbjct: 898 EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATP 957
Query: 439 GNSF--------PPQQAG-----SPLKRPFPAAA----PAVAAAAPAP--APAPAA---- 475
+ PP G SP P P AA P A P+P AP P A
Sbjct: 958 SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017
Query: 476 APALAAAAVAAAAGGAAPSHSQKPS-------VPLIKASRRRPAAGRPTRFVKIAPAIQV 528
+P + AA G + P + PS PL K + PAA P+ K PA
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS--PKGGPATPS 1075
Query: 529 RTGSTGLKATNVEGPVRGAQV---LGCSFKPVQAPGS-----------GAP-APAGISGS 573
G+ A P G G P P S GAP PA S
Sbjct: 1076 LKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS 1135
Query: 574 GLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLV 633
P P P A+ P+P P P T P L
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT--------PAATPPSPKGGLA 1187
Query: 634 SLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSL 693
+ PT P P+G GL+T + G P P+ A +
Sbjct: 1188 TPSPKGAPTTPAATPPSPKG---GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244
Query: 694 LGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQ--LQTQPLRVLQQPVFLATGAVQ 751
+ P+ G P G P P P P ++ L T P + P
Sbjct: 1245 AATPPSPKGGPATPPPKG-APTP-----PAATPPSLKGGLATPPHKGAPNPAV------- 1291
Query: 752 IVQPHPGVQAGSQLVGQRKGGKPTPPA 778
+ P P G KG PTPPA
Sbjct: 1292 VTPPSP---KGGPATSPPKGA-PTPPA 1314
Score = 46.6 bits (109), Expect = 9e-05
Identities = 91/394 (23%), Positives = 126/394 (31%), Gaps = 66/394 (16%)
Query: 393 SVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLK 452
+V LS K P P ++ KG+ PP T + +S P S
Sbjct: 1406 AVIPLSPKKAPATP-VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGD 1464
Query: 453 RPFPAAAPAVAAAAPAP-----APAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKAS 507
PA P PAP + +P APA A A PS ++ VP +S
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKE--VPATPSS 1522
Query: 508 RRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAP 567
RR P A T K PA + A V P + + P A +P
Sbjct: 1523 RRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP 1582
Query: 568 AGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQ 627
++ S + + P P AV + SP
Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSPSP-------------------------------- 1610
Query: 628 QSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQP- 686
++ P A PP P +G A PA + + S L+ P
Sbjct: 1611 --------KEAPTPPAVTPPSP----------EKGPATPAPKGTPTSPPVTPSSLKDSPT 1652
Query: 687 -QAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFL 745
A+V +G A VPQ LP G P L + P P+ + T P R Q
Sbjct: 1653 SPASVTCKMG-ATVPQASKGLPAKKG--PTALKEVLVAPAPESTPIITAPTRKGPQTKKS 1709
Query: 746 ATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 779
+ + I P P + GS+ G P P P
Sbjct: 1710 SATSPPIC-PDPSAKNGSK--GPLSTVAPAPLLP 1740
Score = 45.1 bits (105), Expect = 3e-04
Identities = 86/371 (23%), Positives = 126/371 (33%), Gaps = 64/371 (17%)
Query: 391 PASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQ-QAGS 449
P +++ S KTP P P ++ S K PP T PP + S
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS 1609
Query: 450 PLKRPFPAA----APAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIK 505
P + P P A +P A PAP P + P ++ + A+ + +VP +
Sbjct: 1610 PKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP--Q 1667
Query: 506 ASRRRPAAGRPT--RFVKIAPAIQ--------VRTGSTGLKATNVEGPVRGAQVLGCSFK 555
AS+ PA PT + V +APA + R G K++ P+ C
Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPI-------CPDP 1720
Query: 556 PVQAPGSG-----APAP-------AGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLN 603
+ G APAP + + G +S P P +AS+P F
Sbjct: 1721 SAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAF-- 1778
Query: 604 TPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQ 663
L P+ +V P VSL P PP+ S+ GL +
Sbjct: 1779 ------EKVLPKPESASVSAAPSPP----VSLPLAPSPVPTLPPKQQFLPSSPGLVLESP 1828
Query: 664 AFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQ 723
+ P L P + +L L+ + GV VL P P P
Sbjct: 1829 SKP---------------LAPADEDELLPLIPPEPI-SGGVPFQSVLVNMPTPKSAGIPV 1872
Query: 724 PQPQQIQLQTQ 734
P P Q T+
Sbjct: 1873 PTPSAKQPVTK 1883
Score = 39.7 bits (91), Expect = 0.011
Identities = 63/289 (21%), Positives = 98/289 (33%), Gaps = 21/289 (7%)
Query: 460 PAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSH----SQKPSVPLIKASRRRPAAGR 515
PA P P A P +A +V AA G P+ S P + A+ +
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69
Query: 516 PTRFVKI---APAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISG 572
P+ P Q +G+ T E P ++G P + + G
Sbjct: 70 PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKG 129
Query: 573 SGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLT--GPQQQSH 630
+ S+ L P +VQ SS P + P ++ V + +V+T P S
Sbjct: 130 TPSSSAPLALVALAPHSVQKSSAFPPNLLTSPP------SVAVAESGSVITLSAPIAPSE 183
Query: 631 QLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAV 690
+L ++ P+ P G +ST P + + +G PQ
Sbjct: 184 PKTNLNKV--PSEVVPNPKGTPSPPCIVST----VPYHCVTPMASIQSGVASLPQTTPTT 237
Query: 691 LSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVL 739
+ S QV + + Q P L L P P + L TQ L V+
Sbjct: 238 TLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVV 286
Score = 39.3 bits (90), Expect = 0.014
Identities = 70/276 (25%), Positives = 89/276 (32%), Gaps = 40/276 (14%)
Query: 406 PDPVWVQSSVSGKGEKHPPPRTQ--------LPSSSGKISSGNSFPPQQAGSPLKRPFPA 457
P P ++ KG PP T P G + PP G P P
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG 1308
Query: 458 AAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPT 517
A AA P+P +P P A A PS P++P S + G T
Sbjct: 1309 APTPPAATPPSPKGSPGTPPPKGAPTPPAV---TPPSPKGTPTLPATTPSSK---GGPTT 1362
Query: 518 RFVKIAPAIQVRTGS-TGLKATNVEGPVRGAQV---LGCSFKPVQAPGSGAPAPAGISGS 573
K P T S G A P RG + G P P S APA
Sbjct: 1363 PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA----- 1417
Query: 574 GLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTL-QVPQGWAVLTGPQQQSHQ- 631
P R GA S TP + P++L + P A GP S +
Sbjct: 1418 --------TPVTREGAATPSKGD------LTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463
Query: 632 LVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPA 667
+L + P+ PP P Q +T + A PA
Sbjct: 1464 DPTLPAVTPPSPKEPPAP-KQVATSSSPKKAPATPA 1498
Score = 37.4 bits (85), Expect = 0.054
Identities = 62/261 (23%), Positives = 96/261 (36%), Gaps = 23/261 (8%)
Query: 411 VQSSVSGKGEKHPPPRT----QLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAA 466
V +++ G PPP + Q P S+ +S P A +PL+ PFP ++ A
Sbjct: 34 VTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPL 93
Query: 467 PAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSV-PLIKASRRRPAAGRPTRFVKIAP- 524
AP P L ++ AA A P + P +K + P++ P V +AP
Sbjct: 94 GTAPEAPTFLPNLIGPPISPAALALA-----SPMIAPTLKGT---PSSSAPLALVALAPH 145
Query: 525 AIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPD 584
++Q S+ + P A S + AP AP+ + + + S P P
Sbjct: 146 SVQ---KSSAFPPNLLTSPPSVAVAESGSVITLSAP--IAPSEPKTNLNKVPSEVVPNPK 200
Query: 585 ARPGAVQASSPAPLQF---FLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVS-LQQLQQ 640
P S P + G+ L P + PQ + + S L Q
Sbjct: 201 GTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQN 260
Query: 641 PTAAHPPQPGPQGSTLGLSTQ 661
P + P + L LSTQ
Sbjct: 261 PGSLSLKGPVSPPAALSLSTQ 281
Score = 36.2 bits (82), Expect = 0.12
Identities = 58/241 (24%), Positives = 84/241 (34%), Gaps = 37/241 (15%)
Query: 364 GRAVSQAQESVQSKVKGPGKMSHSSSGPASVS---------------QLSSWKTPEQPDP 408
G V QA + + +K KGP + PA S + S+ P PDP
Sbjct: 1662 GATVPQASKGLPAK-KGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDP 1720
Query: 409 VWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF----------PPQQAGSPL-KRPFPA 457
S P P + S K + G P +A +PL F
Sbjct: 1721 SAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEK 1780
Query: 458 AAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVP-LIKASRRRPAAGRP 516
P +A+ + AP+P + LA + V P PS P L+ S +P A P
Sbjct: 1781 VLPKPESASVSAAPSPPVSLPLAPSPVPT----LPPKQQFLPSSPGLVLESPSKPLA--P 1834
Query: 517 TRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQ 576
++ P I S G+ +V + + G PV P + P GSG +
Sbjct: 1835 ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGI---PVPTPSAKQPVTKNNKGSGTE 1891
Query: 577 S 577
S
Sbjct: 1892 S 1892
Score = 34.3 bits (77), Expect = 0.46
Identities = 38/132 (28%), Positives = 54/132 (40%), Gaps = 16/132 (12%)
Query: 437 SSGNSFPPQQAGSPLKRPFPA---AAPAVAAAAPAPAPAPAAAPALAAAAVAAAAG--GA 491
S+G S+P Q++ P P P+ PA AA P AP+ P+ ++ + +G
Sbjct: 345 STGASYPSQRSVIP---PLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNV 401
Query: 492 APSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATN----VEGPVRGA 547
A S S P+ LI S P A V P V G+T L TN P
Sbjct: 402 ATSFSLSPTTSLILKS--SPNATYHYPLVAQMPVSSV--GTTPLVVTNPCTIAAAPTTTF 457
Query: 548 QVLGCSFKPVQA 559
+V C P+ +
Sbjct: 458 EVATCVSPPMSS 469
>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 6 [Homo sapiens]
Length = 1093
Score = 55.5 bits (132), Expect = 2e-07
Identities = 78/283 (27%), Positives = 105/283 (37%), Gaps = 31/283 (10%)
Query: 451 LKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRR 510
L PFPA PA AA P P P P A ++ + + + P S + S
Sbjct: 757 LSVPFPAL-PAALPAANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSED 815
Query: 511 PAAGRPTRFVKI---------APAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPG 561
P +G P+R P +Q + L P+ G P A
Sbjct: 816 PHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGL 875
Query: 562 SGAPAPAGISGSGLQSSGG-PLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWA 620
P G+ G GL SGG PL G A++P P + G P TLQ+P
Sbjct: 876 GAMPMAEGLLG-GLAGSGGLPLNGLLGGLNGAAAPNPASL---SQAGGAP-TLQLPGCLN 930
Query: 621 VLTGPQQQSH----QLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLT 676
LT +QQ H Q LQQLQQ A+ PQ P+ T+ Q ++L + +
Sbjct: 931 SLT--EQQRHLLQQQEQQLQQLQQLLAS--PQLTPEHQTVVYQMIQQIQQKRELQRLQMA 986
Query: 677 GAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLL 719
G Q + SLL + P P +L P LL
Sbjct: 987 GGS-------QLPMASLLAGSSTPLLSAGTPGLLPTASAPPLL 1022
Score = 33.9 bits (76), Expect = 0.59
Identities = 62/298 (20%), Positives = 98/298 (32%), Gaps = 36/298 (12%)
Query: 330 RPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESV--QSKVKGPGKMSHS 387
+ +++ +QK +K P P + L P A + S A S ++ + + S
Sbjct: 243 KDKERLKQKHKKRPESP-----PSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRE 297
Query: 388 SSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQA 447
S G S S S K + V S S + +SS S P A
Sbjct: 298 SKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSA 357
Query: 448 GSPLKRPFPAAAPAVAAAAPAPAPAPAA------------------APALAAAAVAAAAG 489
L++P A AP+ P+P+A P + + +++G
Sbjct: 358 FPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSG 417
Query: 490 GA-APSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQ 548
A APS S P + S + + P T TGLK + R
Sbjct: 418 RARAPSPGDYKS-PHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRH 476
Query: 549 VLGCSFKPVQAPGSGAPAPAGISGSGLQS---------SGGPLPDARPGAVQASSPAP 597
G G+G PA + + L SGG L + G + + + P
Sbjct: 477 GPGRPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGP 534
Score = 33.1 bits (74), Expect = 1.0
Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 427 TQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAA 486
+QLP +S + +G+S P AG+P P +A P + A A +AAAA AA
Sbjct: 989 SQLPMAS--LLAGSSTPLLSAGTPGLLPTASAPPLLPAGALVAPSLGNNTSLMAAAAAAA 1046
Query: 487 A-AGGAAPSHSQKPSVPLIKASRRRPAAGRP 516
A A P + P + S + G P
Sbjct: 1047 AVAAAGGPPVLTAQTNPFLSLSGAEGSGGGP 1077
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 55.1 bits (131), Expect = 2e-07
Identities = 97/409 (23%), Positives = 143/409 (34%), Gaps = 50/409 (12%)
Query: 348 PDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPD 407
P S RPG G +S + + K K S S+G + +S TP P
Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG---ARRDTSGPTPGTPS 173
Query: 408 PVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAP 467
P + S + E P P+ S + P P K A+ + +P
Sbjct: 174 PAMARRSRAAGTEVGLPR----PAPSAR-------PRPPTEGPRKSVSSASEHSTTEPSP 222
Query: 468 APAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQ 527
A P+A L A + + A P S S P + + R PA P+
Sbjct: 223 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA----------HPSQP 272
Query: 528 VRTGSTGLKATNVEGPVR-GAQVLGCSFKPVQAPGSGAPAPAGISGSGL---QSSGGPLP 583
G L+ V P + A LG P+ + P+P+G + ++ PLP
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALG----PLSSSPLATPSPSGTKARPVPPPDNAATPLP 328
Query: 584 DARPGAVQASSPAPLQFFLNTPEGLRPLTLQ-------VPQGWA---VLTGPQQQSHQLV 633
P + ++P PL P P +LQ P A + T P Q L
Sbjct: 329 ATLPPSPPLATPLPLA----PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ 384
Query: 634 SLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQP-QPQAAVLS 692
++ +Q P + P S L LS+ QA + + T + + P Q QA++ S
Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSL-QATTSLGSPTLQATHSFLTMSPRQTQASLTS 443
Query: 693 LLGSAQVPQQG--VQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVL 739
A P +Q P L P L P P L PL+ L
Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492
Score = 50.8 bits (120), Expect = 5e-06
Identities = 66/263 (25%), Positives = 93/263 (35%), Gaps = 42/263 (15%)
Query: 423 PPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVA-----------AAAPAPAP 471
PPPR ++ + S P SPL +P P A PA+A A+ P AP
Sbjct: 753 PPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAP 812
Query: 472 ---------APAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKI 522
+P A P A V AA P P+ P ++A RR P G T
Sbjct: 813 FSPSASLPMSPLATPPPQAPPVLAAPLLQVP--PSPPASPTLQAPRRPPTPGPDTSVSGP 870
Query: 523 APAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPL 582
+ + G + + + G + G S P +G G ++ P
Sbjct: 871 RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG---AAASPP 927
Query: 583 PDARPGAVQASS----PAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQL 638
PDA A ++ PAP F P P W TGP + L ++ +
Sbjct: 928 PDAELAACHPAAWSRGPAPPLAFRGAP--------GAPLPWPPATGP-GSADGLCTIYET 978
Query: 639 QQPTAAHPP----QPGPQGSTLG 657
+ P +A P PGP T G
Sbjct: 979 EGPESATPAPGALDPGPSPGTSG 1001
Score = 48.1 bits (113), Expect = 3e-05
Identities = 68/246 (27%), Positives = 84/246 (34%), Gaps = 56/246 (22%)
Query: 423 PPPRTQLPSS-------SGKISSGNSFPPQQAGSPLKRPF--PAAAPAVAAAAPAP-APA 472
P P Q P S S + + PP A PL+ P PA+ P +A P P AP
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728
Query: 473 PAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGS 532
P AAP L A+ +PS + P VP + A AP +QV
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLA----------------APPLQV---- 768
Query: 533 TGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQA 592
P + + P QAP + A P L S P P + A
Sbjct: 769 -------PPSPPASLPMSPLAKPPPQAPPALATPPL----QALPSPPASFPGQAPFSPSA 817
Query: 593 SSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGP-QQQSHQLVSLQQLQQPTAAHPPQPGP 651
S P + PL PQ VL P Q + LQ P PP PGP
Sbjct: 818 SLP------------MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP--RRPPTPGP 863
Query: 652 QGSTLG 657
S G
Sbjct: 864 DTSVSG 869
Score = 42.4 bits (98), Expect = 0.002
Identities = 52/209 (24%), Positives = 72/209 (34%), Gaps = 47/209 (22%)
Query: 323 PLLCGKIRPRKKARQKSQKSPWQPFPDDH------SACLRPGSETDAGRAVSQAQESVQS 376
PLL P ++ + P P PD + L PG R+ S S
Sbjct: 838 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS-------S 890
Query: 377 KVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKI 436
+ GP HSSS ++ +L + S G PPP +L +
Sbjct: 891 TLSGPDLAGHSSSATSTPEELRGY-----------DSGPEGGAAASPPPDAELAACHPAA 939
Query: 437 SSGNSFPPQQ----AGSPLKRPFPAAAPAVA-------------AAAPA-----PAPAPA 474
S PP G+PL P PA P A +A PA P P+P
Sbjct: 940 WSRGPAPPLAFRGAPGAPLPWP-PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 998
Query: 475 AAPALAAAAVAAAAGGAAPSHSQKPSVPL 503
+ AAA A A +P ++ +PL
Sbjct: 999 TSGGKAAAGAGAGASSRSPKQARLGELPL 1027
Score = 40.4 bits (93), Expect = 0.006
Identities = 106/504 (21%), Positives = 160/504 (31%), Gaps = 73/504 (14%)
Query: 331 PRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSG 390
P + ++ P QP P A LRP T + + A + S S + +
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQA-LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315
Query: 391 PASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSP 450
P ++ P P S PP P S + S + PP QA
Sbjct: 316 PVPPPDNAATPLPATLPP----SPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371
Query: 451 LKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAA----------------------- 487
+ P A P++ P P +P+L A A
Sbjct: 372 MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLT 431
Query: 488 -------AGGAAPSH--SQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGS------ 532
A +PS S P P ++A PA+ P ++PA+ +
Sbjct: 432 MSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS--PPLQTSLSPAVSPLSSPLTIHPL 489
Query: 533 ---TGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGA 589
+ L + + + P+ + + AP S PA ++ L++ LP P
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLEN----LPSLAPPP 545
Query: 590 VQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTA-AHPPQ 648
+Q +S L TP P LQ P + LT P ++ ++ Q P A A PP
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPP--SPLTTPPPETPSSIATPPPQAPPALASPPL 603
Query: 649 PG------------PQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGS 696
G P + L+ P + L+ + P A + LL +
Sbjct: 604 QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA 663
Query: 697 --AQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQ 754
+ P VQ PF P P+ P L PL+V P
Sbjct: 664 PFSPPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSP---PASPPMSPS 719
Query: 755 PHPGVQAGSQLVGQRKGGKPTPPA 778
P QA L P+PPA
Sbjct: 720 ATPPPQAPPPLAAPPLQVPPSPPA 743
Score = 32.3 bits (72), Expect = 1.7
Identities = 70/292 (23%), Positives = 97/292 (33%), Gaps = 31/292 (10%)
Query: 446 QAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAG--GAAPSHSQKPSVPL 503
+AG+ + P A AP + P +P P AA V AAG G P + +
Sbjct: 9 KAGAAARTP-AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67
Query: 504 IKASRRRPAAGRPTRFVKIA---PAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAP 560
P AG PTR + PA + G +A + G PV +P
Sbjct: 68 ATIPESAPRAG-PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG---------PVSSP 117
Query: 561 G--SGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQG 618
G SG P + GL+ S AR A +A + L G R T G
Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETV-ARGKATEAPKRSALS------AGARRDTSGPTPG 170
Query: 619 W--AVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLT 676
+ + + V L + PP GP+ S S P+
Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR--RRP 228
Query: 677 GAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQ 728
AG GLQ ++ S P + P G P QP+P+ Q
Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSG--PSARGTPRAPAHPSQPKPKGLQ 278
>gi|7662346 ADNP homeobox 2 [Homo sapiens]
Length = 1131
Score = 55.1 bits (131), Expect = 2e-07
Identities = 84/320 (26%), Positives = 118/320 (36%), Gaps = 32/320 (10%)
Query: 456 PAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAA-----GGAAPSHSQKPSVPLIKASRR- 509
PA P A P +P+PAA + A A + A SH S PL
Sbjct: 286 PAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSL 345
Query: 510 --RPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAP 567
+P A +P F+ + L + GPV + +G S P+ P
Sbjct: 346 TLQPPAPQPV-FLSHGVPLHQSVNPPVLPLSQPVGPVNKS--VGTSVLPINQTVRPGVLP 402
Query: 568 AGISGSGLQSSGGP-----LPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGW--- 619
+ GP P PG +QA SP L P G+ P P G
Sbjct: 403 LTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTP 462
Query: 620 -AVLTGPQQQSHQLVSLQQLQQ------PTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLN 672
V+ G S L + Q +Q TA P Q + L + + GQ P+ LL+
Sbjct: 463 AGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPS-GLLS 521
Query: 673 VNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQ 732
N T + S + P Q +L +Q GV LP +GQ +P +L Q I
Sbjct: 522 PNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGV-LP--VGQPVRPGVLQLNQTVGTNILPV 578
Query: 733 TQPLR--VLQQPVFLATGAV 750
QP+R Q FL +G++
Sbjct: 579 NQPVRPGASQNTTFLTSGSI 598
Score = 38.1 bits (87), Expect = 0.032
Identities = 76/307 (24%), Positives = 111/307 (36%), Gaps = 39/307 (12%)
Query: 335 ARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSS----SG 390
A + +P QP P H A + AG+ V+ AQ + S P S S
Sbjct: 278 ANGSAPSAPAQP-PCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSS 336
Query: 391 PASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPP--PRTQLPSSSGKISSGNS------- 441
P V Q S P P PV++ V +PP P +Q P S G S
Sbjct: 337 PLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQ-PVGPVNKSVGTSVLPINQT 395
Query: 442 -----FPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVA-AAAGGAAPSH 495
P Q P+ RP P V +P+ P A + +V+ A G P+
Sbjct: 396 VRPGVLPLTQPVGPINRP---VGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAG 452
Query: 496 SQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVL-GCSF 554
P A + PA P + A + + TG G ++VL
Sbjct: 453 QMTP------AGQMTPAGVIPG---QTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQT 503
Query: 555 KPVQAPGSGAPAPAG-ISGSGLQSSGGPLP---DARPGAVQASSPAPLQFFLNTPEGLRP 610
P++ +G P+G +S + SS +P G +Q S P + L + +RP
Sbjct: 504 APLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPV-VSGVLPVGQPVRP 562
Query: 611 LTLQVPQ 617
LQ+ Q
Sbjct: 563 GVLQLNQ 569
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 55.1 bits (131), Expect = 2e-07
Identities = 60/197 (30%), Positives = 76/197 (38%), Gaps = 27/197 (13%)
Query: 454 PFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSV---------PLI 504
P PA PA PAPAPAPA APALA+AA P P V P+
Sbjct: 505 PTPATTPA-----PAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVE 559
Query: 505 KASRR--RPAAGRPT---------RFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCS 553
+RR RPA RPT R AP + +GS G + + G+ + +
Sbjct: 560 DMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQA-LPRRLVGSSLRAPT 618
Query: 554 FKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTL 613
P P PA S S A P V S+PA + T EG P +
Sbjct: 619 VPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAI 678
Query: 614 Q-VPQGWAVLTGPQQQS 629
VP A+ P+ +S
Sbjct: 679 SGVPTPPAIPPQPRPRS 695
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/129 (29%), Positives = 50/129 (38%), Gaps = 22/129 (17%)
Query: 401 KTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPF----- 455
K P P VSG + PP LP SG + + P + GS L+ P
Sbjct: 566 KRPAPARPTMPPPQVSGS--RSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPL 623
Query: 456 ------PA--------AAPAVAAAAPA-PAPAPAAAPALAAAAVAAAAGGAAPSHSQKPS 500
PA A+P+ A+ PA P+P + PA A A GGA + S P+
Sbjct: 624 PPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAISGVPT 683
Query: 501 VPLIKASRR 509
P I R
Sbjct: 684 PPAIPPQPR 692
Score = 35.0 bits (79), Expect = 0.27
Identities = 45/175 (25%), Positives = 61/175 (34%), Gaps = 15/175 (8%)
Query: 423 PPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAV---AAAAPAPAPA-PAAAPA 478
P P L S++ K + + PP+ A + R P A V A PAPA P P
Sbjct: 519 PAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTKRPAPARPTMPPP 578
Query: 479 LAAAAVAAAAGGAAPSHSQKPSVP------LIKASRRRPAAGRPTRFVKIAPAIQVRTGS 532
+ + ++ P S P P L+ +S R P P PA + S
Sbjct: 579 QVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRS 638
Query: 533 TGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARP 587
+ GP + V P Q A A G + SG P P A P
Sbjct: 639 PASPSPASPGPASPSPV--SLSNPAQVDLGAATAEGGAPEA---ISGVPTPPAIP 688
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 54.7 bits (130), Expect = 3e-07
Identities = 92/359 (25%), Positives = 133/359 (37%), Gaps = 71/359 (19%)
Query: 425 PRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAA----PALA 480
P+ LPS + S+ P QQ +P + P P A P + + +PA P+ A P
Sbjct: 1840 PQQSLPSPT---SAPPGTPTQQPSTP-QTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTV 1895
Query: 481 AAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGL----- 535
+ + A P +Q P + A + A + ++ + G TG+
Sbjct: 1896 STGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGS 1955
Query: 536 ----------KATNVEGPVRGAQVLG---CSFKPVQAPGSGAPAPAGISGSGLQSSGGP- 581
+ V GPV + G + P Q P G P P IS + GP
Sbjct: 1956 QMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPV-ISMQAQAAVAGPR 2014
Query: 582 LPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQ---- 637
+P +P ++ SP+ LQ L TL+ P + PQQQ L L+
Sbjct: 2015 MPSVQP--PRSISPSALQDLLR--------TLKSP------SSPQQQQQVLNILKSNPQL 2058
Query: 638 ----LQQPTAAH-------PPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAG---SGLQ 683
++Q TA + PQPG Q S G+ Q L N+N AG G+
Sbjct: 2059 MAAFIKQRTAKYVANQPGMQPQPGLQ-SQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVP 2117
Query: 684 PQ--------PQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQ 734
PQ PQ L+++ P P + LL Q Q Q QQ Q Q Q
Sbjct: 2118 PQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQ 2176
Score = 43.1 bits (100), Expect = 0.001
Identities = 69/318 (21%), Positives = 109/318 (34%), Gaps = 58/318 (18%)
Query: 384 MSHS----SSGPASVSQLSSWKTPEQPDPVWVQSS---VSGKGEKHPPPRTQLPSSSGKI 436
M+HS S G +S + P+ P+ + ++ + P+ Q PSSSG +
Sbjct: 709 MNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAM 768
Query: 437 SSGNSFPPQQAG------------SPLKRPFPAAA----PAVAAAAPAPAPAPAAAPALA 480
S G PP Q G +PL P A+ P V + P P PA+ A
Sbjct: 769 SVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGM 828
Query: 481 AAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNV 540
+ G P P+ P S + PT P+ +T ++T
Sbjct: 829 PSLQHTTPPGMTPPQPAAPTQPSTPVS---SSGQTPTPTPGSVPS------ATQTQSTPT 879
Query: 541 EGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQF 600
AQV PVQ P P + Q P+ PG + + A +
Sbjct: 880 VQAAAQAQVTPQPQTPVQPPSVATPQSS-------QQQPTPVHAQPPGTPLSQAAASIDN 932
Query: 601 FLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLST 660
+ TP + A QQ V + +++ T A +P P
Sbjct: 933 RVPTPSSV-----------ASAETNSQQPGPDVPVLEMKTETQAEDTEPDP--------G 973
Query: 661 QGQAFPAQQLLNVNLTGA 678
+ + P +++ +L GA
Sbjct: 974 ESKGEPRSEMMEEDLQGA 991
Score = 37.0 bits (84), Expect = 0.070
Identities = 130/576 (22%), Positives = 179/576 (31%), Gaps = 142/576 (24%)
Query: 318 QSFNDPLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSK 377
Q L ++ R+ A ++ P Q P SA PG+ T Q Q +
Sbjct: 1815 QQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSA--PPGTPTQQPSTPQTPQPPAQPQ 1872
Query: 378 VKGPGKMSHSSSGPASV---------------SQLSSWKTPEQPDPVWVQSSVSGKGEKH 422
P +S S +G SV SQ+ + P QP P V+++ + E
Sbjct: 1873 ---PSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQ 1929
Query: 423 --------------PPPRTQL--PSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAA 466
PP RT + P S S N P Q P+ P+ P A
Sbjct: 1930 QQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPV---MPSMPPGQWQQA 1986
Query: 467 PAPAPAPAAA---PALAAAAVAAAAGGAAPSHS-----------------QKPSVP---- 502
P P P P ++ A AA AG PS + PS P
Sbjct: 1987 PLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQ 2046
Query: 503 ----LIKASRRRPAA---GRPTRFVKIAPAIQVRTGSTGLKATNVE-GPVRGAQVLGCSF 554
++K++ + AA R ++V P +Q + G + G + + +
Sbjct: 2047 QVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNA 2106
Query: 555 KPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQ 614
P G P G GL G L PG +P E LR LQ
Sbjct: 2107 MQAGVPRPGVPPQQQAMG-GLNPQGQALNIMNPG----HNPNMASMNPQYREMLRRQLLQ 2161
Query: 615 VPQGWAVLTGPQQQSHQ--------LVSLQQLQQPTA--AHPP-----QPGPQGSTLGLS 659
Q QQQ Q + Q QQP +PP Q Q L S
Sbjct: 2162 QQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGS 2221
Query: 660 TQGQ-AFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLP----------F 708
+ GQ A QL + G G+ P Q A+ + Q +Q + P
Sbjct: 2222 SMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQH 2281
Query: 709 VLGQQPQ------------------------------------PLLLLQPQPQPQQIQLQ 732
+L QPQ P +QPQP P + Q
Sbjct: 2282 MLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQ 2341
Query: 733 TQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQ 768
T P T A I Q H G S ++ Q
Sbjct: 2342 TGS----PHPGLAVTMASSIDQGHLGNPEQSAMLPQ 2373
Score = 30.4 bits (67), Expect = 6.6
Identities = 59/222 (26%), Positives = 75/222 (33%), Gaps = 32/222 (14%)
Query: 581 PLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQ 640
P P A+P + + P N P L +QV QG + QL Q
Sbjct: 648 PAPGAQPPVIPQAQPVRPP---NGPLSLPVNRMQVSQGMNSFNPMSLGNVQLP--QAPMG 702
Query: 641 PTAAHPPQPGPQGSTLGLSTQGQAF-PAQQLLNVNLTG-----------AGSGLQPQ--- 685
P AA P Q +++G S G A P++ N+ G A S PQ
Sbjct: 703 PRAASPMNHSVQMNSMG-SVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQF 761
Query: 686 PQAAVLSLLGSAQVP-QQGVQLPFVLGQQ-PQPLLLLQPQPQPQQIQLQTQ-PLRVLQQP 742
P ++ +G Q P Q GV V G P PL +L PQ TQ PL P
Sbjct: 762 PSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPP 821
Query: 743 VFLATGAVQI--------VQPHPGVQAGSQLVGQRKGGKPTP 776
A G + P P G PTP
Sbjct: 822 ASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTP 863
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 54.7 bits (130), Expect = 3e-07
Identities = 92/359 (25%), Positives = 133/359 (37%), Gaps = 71/359 (19%)
Query: 425 PRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAA----PALA 480
P+ LPS + S+ P QQ +P + P P A P + + +PA P+ A P
Sbjct: 1878 PQQSLPSPT---SAPPGTPTQQPSTP-QTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTV 1933
Query: 481 AAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGL----- 535
+ + A P +Q P + A + A + ++ + G TG+
Sbjct: 1934 STGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGS 1993
Query: 536 ----------KATNVEGPVRGAQVLG---CSFKPVQAPGSGAPAPAGISGSGLQSSGGP- 581
+ V GPV + G + P Q P G P P IS + GP
Sbjct: 1994 QMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPV-ISMQAQAAVAGPR 2052
Query: 582 LPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQ---- 637
+P +P ++ SP+ LQ L TL+ P + PQQQ L L+
Sbjct: 2053 MPSVQP--PRSISPSALQDLLR--------TLKSP------SSPQQQQQVLNILKSNPQL 2096
Query: 638 ----LQQPTAAH-------PPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAG---SGLQ 683
++Q TA + PQPG Q S G+ Q L N+N AG G+
Sbjct: 2097 MAAFIKQRTAKYVANQPGMQPQPGLQ-SQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVP 2155
Query: 684 PQ--------PQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQ 734
PQ PQ L+++ P P + LL Q Q Q QQ Q Q Q
Sbjct: 2156 PQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQ 2214
Score = 43.1 bits (100), Expect = 0.001
Identities = 69/318 (21%), Positives = 109/318 (34%), Gaps = 58/318 (18%)
Query: 384 MSHS----SSGPASVSQLSSWKTPEQPDPVWVQSS---VSGKGEKHPPPRTQLPSSSGKI 436
M+HS S G +S + P+ P+ + ++ + P+ Q PSSSG +
Sbjct: 747 MNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAM 806
Query: 437 SSGNSFPPQQAG------------SPLKRPFPAAA----PAVAAAAPAPAPAPAAAPALA 480
S G PP Q G +PL P A+ P V + P P PA+ A
Sbjct: 807 SVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGM 866
Query: 481 AAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNV 540
+ G P P+ P S + PT P+ +T ++T
Sbjct: 867 PSLQHTTPPGMTPPQPAAPTQPSTPVS---SSGQTPTPTPGSVPS------ATQTQSTPT 917
Query: 541 EGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQF 600
AQV PVQ P P + Q P+ PG + + A +
Sbjct: 918 VQAAAQAQVTPQPQTPVQPPSVATPQSS-------QQQPTPVHAQPPGTPLSQAAASIDN 970
Query: 601 FLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLST 660
+ TP + A QQ V + +++ T A +P P
Sbjct: 971 RVPTPSSV-----------ASAETNSQQPGPDVPVLEMKTETQAEDTEPDP--------G 1011
Query: 661 QGQAFPAQQLLNVNLTGA 678
+ + P +++ +L GA
Sbjct: 1012 ESKGEPRSEMMEEDLQGA 1029
Score = 37.0 bits (84), Expect = 0.070
Identities = 130/576 (22%), Positives = 179/576 (31%), Gaps = 142/576 (24%)
Query: 318 QSFNDPLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSK 377
Q L ++ R+ A ++ P Q P SA PG+ T Q Q +
Sbjct: 1853 QQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSA--PPGTPTQQPSTPQTPQPPAQPQ 1910
Query: 378 VKGPGKMSHSSSGPASV---------------SQLSSWKTPEQPDPVWVQSSVSGKGEKH 422
P +S S +G SV SQ+ + P QP P V+++ + E
Sbjct: 1911 ---PSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQ 1967
Query: 423 --------------PPPRTQL--PSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAA 466
PP RT + P S S N P Q P+ P+ P A
Sbjct: 1968 QQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPV---MPSMPPGQWQQA 2024
Query: 467 PAPAPAPAAA---PALAAAAVAAAAGGAAPSHS-----------------QKPSVP---- 502
P P P P ++ A AA AG PS + PS P
Sbjct: 2025 PLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQ 2084
Query: 503 ----LIKASRRRPAA---GRPTRFVKIAPAIQVRTGSTGLKATNVE-GPVRGAQVLGCSF 554
++K++ + AA R ++V P +Q + G + G + + +
Sbjct: 2085 QVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNA 2144
Query: 555 KPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQ 614
P G P G GL G L PG +P E LR LQ
Sbjct: 2145 MQAGVPRPGVPPQQQAMG-GLNPQGQALNIMNPG----HNPNMASMNPQYREMLRRQLLQ 2199
Query: 615 VPQGWAVLTGPQQQSHQ--------LVSLQQLQQPTA--AHPP-----QPGPQGSTLGLS 659
Q QQQ Q + Q QQP +PP Q Q L S
Sbjct: 2200 QQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGS 2259
Query: 660 TQGQ-AFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLP----------F 708
+ GQ A QL + G G+ P Q A+ + Q +Q + P
Sbjct: 2260 SMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQH 2319
Query: 709 VLGQQPQ------------------------------------PLLLLQPQPQPQQIQLQ 732
+L QPQ P +QPQP P + Q
Sbjct: 2320 MLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQ 2379
Query: 733 TQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQ 768
T P T A I Q H G S ++ Q
Sbjct: 2380 TGS----PHPGLAVTMASSIDQGHLGNPEQSAMLPQ 2411
Score = 30.4 bits (67), Expect = 6.6
Identities = 59/222 (26%), Positives = 75/222 (33%), Gaps = 32/222 (14%)
Query: 581 PLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQ 640
P P A+P + + P N P L +QV QG + QL Q
Sbjct: 686 PAPGAQPPVIPQAQPVRPP---NGPLSLPVNRMQVSQGMNSFNPMSLGNVQLP--QAPMG 740
Query: 641 PTAAHPPQPGPQGSTLGLSTQGQAF-PAQQLLNVNLTG-----------AGSGLQPQ--- 685
P AA P Q +++G S G A P++ N+ G A S PQ
Sbjct: 741 PRAASPMNHSVQMNSMG-SVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQF 799
Query: 686 PQAAVLSLLGSAQVP-QQGVQLPFVLGQQ-PQPLLLLQPQPQPQQIQLQTQ-PLRVLQQP 742
P ++ +G Q P Q GV V G P PL +L PQ TQ PL P
Sbjct: 800 PSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPP 859
Query: 743 VFLATGAVQI--------VQPHPGVQAGSQLVGQRKGGKPTP 776
A G + P P G PTP
Sbjct: 860 ASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTP 901
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 54.3 bits (129), Expect = 4e-07
Identities = 93/383 (24%), Positives = 128/383 (33%), Gaps = 73/383 (19%)
Query: 331 PRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSG 390
PRK S+ S +P P +A RP + R S++ S + + P + S+ G
Sbjct: 196 PRKSVSSASEHSTTEPSP---AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 252
Query: 391 ----PASVSQ-----LSSWKTPEQPDPVWVQSSVSGKGEKHP--------PPRTQLPSSS 433
PA SQ L + + P+ P + G P PP P S
Sbjct: 253 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL 312
Query: 434 GKISSGNSFPPQQAG--------------------SPLKRPFPAAAPAVAAAAPAPAPAP 473
+ S + PP QA SPL P P A PA+A P+P
Sbjct: 313 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP 372
Query: 474 AAAPALA-----------AAAVAAAAGGAAPSHS-------QKPSVPLIKASRRRPAAGR 515
A+P L+ A AV +P S P+ P + S P+
Sbjct: 373 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432
Query: 516 PTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGL 575
P+ AP +QV + + P+Q AP ++ L
Sbjct: 433 PS---LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 489
Query: 576 QSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGP-QQQSHQLVS 634
Q+ P P + PG S A L + PL PQ VL P Q +
Sbjct: 490 QALPSP-PASFPGQAPFSPSASLP--------MSPLATPPPQAPPVLAAPLLQVPPSPPA 540
Query: 635 LQQLQQPTAAHPPQPGPQGSTLG 657
LQ P PP PGP S G
Sbjct: 541 SPTLQAP--RRPPTPGPDTSVSG 561
Score = 50.4 bits (119), Expect = 6e-06
Identities = 107/438 (24%), Positives = 143/438 (32%), Gaps = 55/438 (12%)
Query: 348 PDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPD 407
P S RPG G +S + + K K S S+G + +S TP P
Sbjct: 108 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG---ARRDTSGPTPGTPS 164
Query: 408 PVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAP 467
P + S + E P P+ S + P P K A+ + +P
Sbjct: 165 PAMARRSRAAGTEVGLPR----PAPSAR-------PRPPTEGPRKSVSSASEHSTTEPSP 213
Query: 468 APAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQ 527
A P+A L A + + A P S S P + + R PA P+
Sbjct: 214 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA----------HPSQP 263
Query: 528 VRTGSTGLKATNVEGPVR-GAQVLG-CSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDA 585
G L+ V P + A LG S P+ P AP P+ + LQ+ P P
Sbjct: 264 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP-PSPSAPPSLQTLPSP-PAT 321
Query: 586 RPGAVQASSPAP----LQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQP 641
P S +P FL +P L PL PQ L P Q+
Sbjct: 322 PPSQATTSLGSPTLQATHSFLPSPP-LSPLATPPPQAPPALALPPLQA------------ 368
Query: 642 TAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQA-AVLSLLGSAQVP 700
PP P L+T P L V+L A P P A S S V
Sbjct: 369 ----PPSPPASPPLSPLATPSPQAP--NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422
Query: 701 QQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQPHPGVQ 760
P L + P P P + Q P LA +Q+ +P P Q
Sbjct: 423 PSATPPSQAPPSLAAPPLQVPPSP-PASPPMSPSATPPPQAPPPLAAPPLQLAKPPP--Q 479
Query: 761 AGSQLVGQRKGGKPTPPA 778
A L P+PPA
Sbjct: 480 APPALATPPLQALPSPPA 497
Score = 48.5 bits (114), Expect = 2e-05
Identities = 92/361 (25%), Positives = 134/361 (37%), Gaps = 52/361 (14%)
Query: 416 SGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAA 475
SG+GE+ PP + +S G +SS P + +G+ P ++A
Sbjct: 88 SGRGERAPPAKN---TSPGPVSS----PGRASGTTRPGPLGQKGLRISAEETVARGKATE 140
Query: 476 APALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGL 535
AP +A + A + P+ P P +RR AAG + AP+ + R + G
Sbjct: 141 APKRSALSAGARRDTSGPT----PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196
Query: 536 KATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPD-ARPGAVQASS 594
+ + + + + G G PA S L SS PL AR G +
Sbjct: 197 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS---LSSSATPLSSPARSGPSARGT 253
Query: 595 P-APLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQL---VSLQQLQQPTAAHPPQPG 650
P AP P+GL+ L+ PQ +T P++ + +S L P+ + PP P
Sbjct: 254 PRAPAHPSQPKPKGLQ--ALRPPQ----VTPPRKDAAPALGPLSSSPLATPSPSAPPSPS 307
Query: 651 PQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVL 710
S L + P+Q A + L A S L S + P
Sbjct: 308 APPSLQTLPSPPATPPSQ---------ATTSLGSPTLQATHSFLPSPPLSPLATPPP--- 355
Query: 711 GQQPQPLLL--LQPQPQPQQIQLQTQPLRVLQQPVFLATG--AVQIVQ------PHPGVQ 760
Q P L L LQ P P + PL L P A AV ++Q P P VQ
Sbjct: 356 -QAPPALALPPLQAPPSPP----ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 410
Query: 761 A 761
A
Sbjct: 411 A 411
Score = 42.4 bits (98), Expect = 0.002
Identities = 52/209 (24%), Positives = 72/209 (34%), Gaps = 47/209 (22%)
Query: 323 PLLCGKIRPRKKARQKSQKSPWQPFPDDH------SACLRPGSETDAGRAVSQAQESVQS 376
PLL P ++ + P P PD + L PG R+ S S
Sbjct: 530 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS-------S 582
Query: 377 KVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKI 436
+ GP HSSS ++ +L + S G PPP +L +
Sbjct: 583 TLSGPDLAGHSSSATSTPEELRGY-----------DSGPEGGAAASPPPDAELAACHPAA 631
Query: 437 SSGNSFPPQQ----AGSPLKRPFPAAAPAVA-------------AAAPA-----PAPAPA 474
S PP G+PL P PA P A +A PA P P+P
Sbjct: 632 WSRGPAPPLAFRGAPGAPLPWP-PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 690
Query: 475 AAPALAAAAVAAAAGGAAPSHSQKPSVPL 503
+ AAA A A +P ++ +PL
Sbjct: 691 TSGGKAAAGAGAGASSRSPKQARLGELPL 719
Score = 33.1 bits (74), Expect = 1.0
Identities = 80/322 (24%), Positives = 108/322 (33%), Gaps = 46/322 (14%)
Query: 446 QAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAG--------------GA 491
+AG+ + P A AP + P +P P AA V AAG G
Sbjct: 9 KAGAAARTP-AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67
Query: 492 APSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTG----LKATNVEGPVRGA 547
A P + S R PA+GR R PA G T GP+ G
Sbjct: 68 ATIPESAPRAGPTRTS-RPPASGRGER---APPAKNTSPGPVSSPGRASGTTRPGPL-GQ 122
Query: 548 QVLGCSFKPVQAPGSGAPAP--AGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTP 605
+ L S + A G AP + +S + + GP P A+ S A T
Sbjct: 123 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA-----AGTE 177
Query: 606 EGL-RPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPG-------PQGSTLG 657
GL RP P+ GP ++S S +P+ A +P P +L
Sbjct: 178 VGLPRPAPSARPR--PPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 234
Query: 658 LSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQV-PQQGVQLPFVLGQQPQP 716
S + PA+ + T QP+ L L QV P + P + P
Sbjct: 235 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 294
Query: 717 LLLLQPQPQPQQI---QLQTQP 735
L P P LQT P
Sbjct: 295 LATPSPSAPPSPSAPPSLQTLP 316
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,652,847
Number of Sequences: 37866
Number of extensions: 2392807
Number of successful extensions: 25693
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 350
Number of HSP's successfully gapped in prelim test: 1377
Number of HSP's that attempted gapping in prelim test: 13940
Number of HSP's gapped (non-prelim): 7211
length of query: 779
length of database: 18,247,518
effective HSP length: 110
effective length of query: 669
effective length of database: 14,082,258
effective search space: 9421030602
effective search space used: 9421030602
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.