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Search of human proteins with 118421089
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118421089 chromodomain helicase DNA binding protein 2
isoform 1 [Homo sapiens]
(1828 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 3718 0.0
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 1969 0.0
gi|110611184 chromodomain helicase DNA binding protein 2 isoform... 1014 0.0
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 591 e-168
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 581 e-165
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 581 e-165
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 577 e-164
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 568 e-161
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 545 e-154
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa... 533 e-151
gi|114326455 chromodomain helicase DNA binding protein 8 [Homo s... 531 e-150
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 523 e-148
gi|164419749 SWI/SNF-related matrix-associated actin-dependent r... 462 e-129
gi|21071044 SWI/SNF-related matrix-associated actin-dependent re... 453 e-127
gi|21071058 SWI/SNF-related matrix-associated actin-dependent re... 449 e-125
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 422 e-117
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r... 422 e-117
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 421 e-117
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r... 421 e-117
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r... 412 e-114
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re... 412 e-114
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 408 e-113
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 408 e-113
gi|148612870 chromodomain helicase DNA binding protein 1-like [H... 405 e-112
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 395 e-109
gi|21914927 helicase, lymphoid-specific [Homo sapiens] 307 7e-83
gi|190358536 SWI/SNF-related, matrix-associated actin-dependent ... 298 4e-80
gi|190358532 SWI/SNF-related, matrix-associated actin-dependent ... 298 4e-80
gi|190358534 SWI/SNF-related, matrix-associated actin-dependent ... 295 4e-79
gi|4557565 excision repair cross-complementing rodent repair def... 264 7e-70
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 3718 bits (9642), Expect = 0.0
Identities = 1828/1828 (100%), Positives = 1828/1828 (100%)
Query: 1 MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS 60
MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS
Sbjct: 1 MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS 60
Query: 61 ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS 120
ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS
Sbjct: 61 ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS 120
Query: 121 RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP 180
RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP
Sbjct: 121 RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP 180
Query: 181 VPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFET 240
VPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFET
Sbjct: 181 VPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFET 240
Query: 241 DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEK 300
DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEK
Sbjct: 241 DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEK 300
Query: 301 DEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDV 360
DEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDV
Sbjct: 301 DEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDV 360
Query: 361 EYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGL 420
EYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGL
Sbjct: 361 EYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGL 420
Query: 421 PYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGE 480
PYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGE
Sbjct: 421 PYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGE 480
Query: 481 NLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVV 540
NLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVV
Sbjct: 481 NLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVV 540
Query: 541 PLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILL 600
PLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILL
Sbjct: 541 PLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILL 600
Query: 601 KDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLL 660
KDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLL
Sbjct: 601 KDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLL 660
Query: 661 HFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVE 720
HFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVE
Sbjct: 661 HFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVE 720
Query: 721 MSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIKPPEENERENGQ 780
MSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIKPPEENERENGQ
Sbjct: 721 MSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIKPPEENERENGQ 780
Query: 781 EILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGS 840
EILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGS
Sbjct: 781 EILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGS 840
Query: 841 IKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQAR 900
IKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQAR
Sbjct: 841 IKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQAR 900
Query: 901 AHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNS 960
AHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNS
Sbjct: 901 AHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNS 960
Query: 961 NPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQ 1020
NPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQ
Sbjct: 961 NPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQ 1020
Query: 1021 FKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKA 1080
FKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKA
Sbjct: 1021 FKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKA 1080
Query: 1081 QTNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFI 1140
QTNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFI
Sbjct: 1081 QTNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFI 1140
Query: 1141 KAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKENASEGK 1200
KAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKENASEGK
Sbjct: 1141 KAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKENASEGK 1200
Query: 1201 GPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVE 1260
GPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVE
Sbjct: 1201 GPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVE 1260
Query: 1261 WGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKL 1320
WGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKL
Sbjct: 1261 WGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKL 1320
Query: 1321 LRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKD 1380
LRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKD
Sbjct: 1321 LRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKD 1380
Query: 1381 DGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKR 1440
DGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKR
Sbjct: 1381 DGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKR 1440
Query: 1441 SQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLE 1500
SQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLE
Sbjct: 1441 SQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLE 1500
Query: 1501 HTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRS 1560
HTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRS
Sbjct: 1501 HTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDARKLHKLYKMAHKKRS 1560
Query: 1561 QEEEEQKKKDDVTGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKPHLPASHGPQMHGHP 1620
QEEEEQKKKDDVTGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKPHLPASHGPQMHGHP
Sbjct: 1561 QEEEEQKKKDDVTGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKPHLPASHGPQMHGHP 1620
Query: 1621 RDNYNHPNKRHFSNADRGDWQRERKFNYGGGNNNPPWGSDRHHQYEQHWYKDHHYGDRRH 1680
RDNYNHPNKRHFSNADRGDWQRERKFNYGGGNNNPPWGSDRHHQYEQHWYKDHHYGDRRH
Sbjct: 1621 RDNYNHPNKRHFSNADRGDWQRERKFNYGGGNNNPPWGSDRHHQYEQHWYKDHHYGDRRH 1680
Query: 1681 MDAHRSGSYRPNNMSRKRPYDQYSSDRDHRGHRDYYDRHHHDSKRRRSDEFRPQNYHQQD 1740
MDAHRSGSYRPNNMSRKRPYDQYSSDRDHRGHRDYYDRHHHDSKRRRSDEFRPQNYHQQD
Sbjct: 1681 MDAHRSGSYRPNNMSRKRPYDQYSSDRDHRGHRDYYDRHHHDSKRRRSDEFRPQNYHQQD 1740
Query: 1741 FRRMSDHRPAMGYHGQGPSDHYRSFHTDKLGEYKQPLPPLHPAVSDPRSPPSQKSPHDSK 1800
FRRMSDHRPAMGYHGQGPSDHYRSFHTDKLGEYKQPLPPLHPAVSDPRSPPSQKSPHDSK
Sbjct: 1741 FRRMSDHRPAMGYHGQGPSDHYRSFHTDKLGEYKQPLPPLHPAVSDPRSPPSQKSPHDSK 1800
Query: 1801 SPLDHRSPLERSLEQKNNPDYNWNVRKT 1828
SPLDHRSPLERSLEQKNNPDYNWNVRKT
Sbjct: 1801 SPLDHRSPLERSLEQKNNPDYNWNVRKT 1828
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 1969 bits (5101), Expect = 0.0
Identities = 1050/1843 (56%), Positives = 1289/1843 (69%), Gaps = 168/1843 (9%)
Query: 20 SSHSASEEA-SGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQS-ESESES---AGSK 74
+ HS E + S SQS+ + GS GSG GS S SSS+ S SQS S+S+S +GS+
Sbjct: 2 NGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQ 61
Query: 75 SQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRS-----------NRSRQEPSRFN 123
S+ ++E K D + W+ P + V+RS + Q S
Sbjct: 62 SESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSG 121
Query: 124 IKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPV-- 181
+E++SS +S +R+ K E W+ S + G+ +ESE E++K
Sbjct: 122 SEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESD 181
Query: 182 --PRRTVPKPRVKKQPKTQRGKR-----KKQ-DSSDEDDDDDEAP--KRQTRRRAAKNVS 231
P+ V + + + K++ GK+ K+Q DSS+EDDD+++ KR +RR+A NVS
Sbjct: 182 YEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNVS 241
Query: 232 YKEDDDFETDSDDLIEMTGEGVDE-QQDNSETIEKVLDSRLGKKGATGASTTVYAIEANG 290
YKED++ +TDSDDL+E+ GE V + +++ ETIE+ +D R+G+KGATGA+TT+YA+EA+G
Sbjct: 242 YKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEADG 301
Query: 291 DPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQ 350
DP+ F+ K+ GEIQYLIKWKGWS+IH+TWE+EE+L+QQ V+G+KKL+N+KKK+ E K+
Sbjct: 302 DPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKR 361
Query: 351 WLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNE 410
WL SPEDVEY+NCQQEL +L+KQYQIVER+IA HS + + +
Sbjct: 362 WLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIA---------------HSNQKSAAGY 406
Query: 411 PEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVAL 470
P+Y CKW GLPYSECSWED ALI KKFQ CID + SRN SKT P ++CK LKQRPRFVAL
Sbjct: 407 PDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVAL 466
Query: 471 KKQPAYLGG-ENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQ 529
KKQP+Y+GG E LELRDYQL GLNWLAHSWCK NS ILADEMGLGKTIQTISFL+YLFH+
Sbjct: 467 KKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHE 526
Query: 530 HQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKF 589
HQLYGPFL+VVPLSTLTSWQRE + WA ++N VVY+GD+ SRN IR +EW H QTKRLKF
Sbjct: 527 HQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKF 586
Query: 590 NALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPL 649
N L+TTYEILLKDK LG +NWAF+GVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPL
Sbjct: 587 NILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPL 646
Query: 650 QNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSL 709
QNSLKELWSLLHFIMPEKF WEDFEE+HGKGRE GY SLHK LEPFLLRRVKKDVEKSL
Sbjct: 647 QNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSL 706
Query: 710 PAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIK 769
PAKVEQILR+EMSALQKQYYKWILTRNYKAL+KG++GSTSGFLNI+MELKKCCNHCYLIK
Sbjct: 707 PAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIK 766
Query: 770 PPEENERENGQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTI 829
PP+ NE N QE L LIRSSGKLILLDKLL RLRERGNRVLIFSQMVRMLDILAEYL
Sbjct: 767 PPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKY 826
Query: 830 KHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDW 889
+ +PFQRLDGSIKGE+RKQALDHFNA+GSEDFCFLLSTRAGGLGINLASADTVVIFDSDW
Sbjct: 827 RQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDW 886
Query: 890 NPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRT 949
NPQNDLQAQARAHRIGQKKQVNIYRLVTKG+VEE+I+ERAKKKMVLDHLVIQRMDTTG+T
Sbjct: 887 NPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKT 946
Query: 950 ILENNSGRSNSNPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEV 1009
+L S S+S PFNKEEL+AILKFGAE+LFKE EGEE EPQEMDIDEIL+ AET ENE
Sbjct: 947 VLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEP 1006
Query: 1010 S-TSATDELLSQFKVANFATM-EDEEELE-ERPHKDWDEIIPEEQRKKVEEEERQKELEE 1066
+ DELLSQFKVANF+ M ED+ ELE ER K+W+EIIPE+QR+++EEEERQKELEE
Sbjct: 1007 GPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEE 1066
Query: 1067 IYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKD 1126
IYMLPR+R+ K+ N S+ R+++ S S+++ + K+PK+RGRPR++ ++
Sbjct: 1067 IYMLPRMRNCAKQISFNGSEG-----RRSRSRRYSGSDSDSISEGKRPKKRGRPRTIPRE 1121
Query: 1127 LVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQ 1186
++GF+DAEIRRFIK+YKKFG PLERL+ IARDAELVDKS DL+RLGEL+HN C+ A++
Sbjct: 1122 NIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALK 1181
Query: 1187 EYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKY 1246
+ + G GK +GPT +ISGVQVN K +I HEEE LHKSIP DPEE+K+Y
Sbjct: 1182 DSSSGTERT---GGRLGKVKGPTFRISGVQVNAKLVISHEEELIPLHKSIPSDPEERKQY 1238
Query: 1247 CLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQ 1306
+ C KAAHFD++WG EDDS LL+GIYE+GYG+WE+IK DP+L LT KILP + DKKPQ
Sbjct: 1239 TIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQ 1298
Query: 1307 GKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSP 1366
KQLQTRADYL+KLL + L KK A++G + K+RK R KK + +K + I+ S
Sbjct: 1299 AKQLQTRADYLIKLLSRDLAKKEALSGAGSS--KRRKARAKKNKAMKSIKVKEEIKSDS- 1355
Query: 1367 RHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEK 1426
S PSE+ + DD L +S
Sbjct: 1356 --SPLPSEKSDEDDDKLSES---------------------------------------- 1373
Query: 1427 PKSGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQL 1486
KS + S KS S PVHITA EPVPI E E ++LDQ+TFSICKERMRPVK ALKQL
Sbjct: 1374 -KSDGRERSKKSSVSDAPVHITASGEPVPISE-ESEELDQKTFSICKERMRPVKAALKQL 1431
Query: 1487 DKPDKGLNVQEQLEHTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDAR 1546
D+P+KGL+ +EQLEHTR CL+KIGD I ECLK Y++ E IK WR+NLWIFVSKFTEFDAR
Sbjct: 1432 DRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDAR 1491
Query: 1547 KLHKLYKMAHKKRSQEEEEQKKKDDVTGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKP 1606
KLHKLYK A KKR +E ++ D P R + +T+H+ +
Sbjct: 1492 KLHKLYKHAIKKR----QESQQNSDQNSNLNPHVIRNPDVER----LKENTNHDDSSRDS 1543
Query: 1607 HLPASHGPQMHGHPRDNYNHPNKRHFSNADRGDWQRERKF-NYGGGNNNPPWGSDRHHQY 1665
+ H Q H H +D RH ++ + R+R + ++ G ++ W H++
Sbjct: 1544 YSSDRHLTQYHDHHKD-------RHQGDSYKKSDSRKRPYSSFSNGKDHRDWD---HYKQ 1593
Query: 1666 EQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYDQYSSDRDHRGHRDYYDRHHHDSKR 1725
+ +Y D R +D HRS +R N + DR H HR + D H
Sbjct: 1594 DSRYYSDRE--KHRKLDDHRSRDHRSN-------LEGSLKDRSHSDHRSHSDHRLH---- 1640
Query: 1726 RRSDEFRPQNYHQQDFRRMSDHRPAMGYHGQGPSDHYRSFHTDKLGEYKQPLPPLHPAVS 1785
SDHR + Y S YR +H+D +++ + S
Sbjct: 1641 -------------------SDHRSSSEYTHHKSSRDYR-YHSDWQMDHR-------ASSS 1673
Query: 1786 DPRSPPSQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT 1828
PRSP Q+SP+ S+SP +H S+E K+ P++ W+ RKT
Sbjct: 1674 GPRSPLDQRSPYGSRSPFEH------SVEHKSTPEHTWSSRKT 1710
>gi|110611184 chromodomain helicase DNA binding protein 2 isoform 2
[Homo sapiens]
Length = 501
Score = 1014 bits (2623), Expect = 0.0
Identities = 501/501 (100%), Positives = 501/501 (100%)
Query: 1 MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS 60
MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS
Sbjct: 1 MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS 60
Query: 61 ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS 120
ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS
Sbjct: 61 ESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS 120
Query: 121 RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP 180
RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP
Sbjct: 121 RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRP 180
Query: 181 VPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFET 240
VPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFET
Sbjct: 181 VPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFET 240
Query: 241 DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEK 300
DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEK
Sbjct: 241 DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEK 300
Query: 301 DEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDV 360
DEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDV
Sbjct: 301 DEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDV 360
Query: 361 EYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGL 420
EYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGL
Sbjct: 361 EYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGL 420
Query: 421 PYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGE 480
PYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGE
Sbjct: 421 PYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGE 480
Query: 481 NLELRDYQLEGLNWLAHSWCK 501
NLELRDYQLEGLNWLAHSWCK
Sbjct: 481 NLELRDYQLEGLNWLAHSWCK 501
Score = 39.3 bits (90), Expect = 0.036
Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 12/96 (12%)
Query: 1029 MEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSD 1088
++ +E+ ++ P +D +EQ E E QK+++ +PR + K +
Sbjct: 145 LKKQEKWKQEPSED-----EQEQGTSAESEPEQKKVKARRPVPR--RTVPKPRVKKQPKT 197
Query: 1089 TESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVR 1124
KR+ Q SS ED DDD+ PKR+ R R+ +
Sbjct: 198 QRGKRKKQDSS-----DEDDDDDEAPKRQTRRRAAK 228
Score = 36.2 bits (82), Expect = 0.30
Identities = 36/135 (26%), Positives = 56/135 (41%), Gaps = 10/135 (7%)
Query: 1341 KRKPRVKKEN--KVPRLKEEH----GIELSSPRHSDNPSEEG--EVKDDGLEKSPMKKKQ 1392
K KP KKE V ++ EE+ G+ S+ R PS E G E K++
Sbjct: 83 KEKPASKKERIADVKKMWEEYPDVYGVRRSN-RSRQEPSRFNIKEEASSGSESGSPKRRG 141
Query: 1393 KKKENKENKEKQMSSRKDKE-GDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAGS 1451
+++ K+ K KQ S ++E G + + KK K + + + R + G
Sbjct: 142 QRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGK 201
Query: 1452 EPVPIGEDEDDDLDQ 1466
DEDDD D+
Sbjct: 202 RKKQDSSDEDDDDDE 216
Score = 31.2 bits (69), Expect = 9.7
Identities = 27/133 (20%), Positives = 56/133 (42%), Gaps = 5/133 (3%)
Query: 1335 EEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKK 1394
E+ K+K R+P ++ PR+K++ + + D+ S+E + D+ ++ ++ K
Sbjct: 171 EQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDS-SDEDDDDDEAPKRQTRRRAAKN 229
Query: 1395 KENKENKEKQMSS----RKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAG 1450
KE+ + + S EG E++ + + EK + S I A
Sbjct: 230 VSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEAN 289
Query: 1451 SEPVPIGEDEDDD 1463
+P + E D+
Sbjct: 290 GDPSGDFDTEKDE 302
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 591 bits (1524), Expect = e-168
Identities = 415/1222 (33%), Positives = 621/1222 (50%), Gaps = 168/1222 (13%)
Query: 304 EIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLG---------- 353
E Q+ +KW+G SY H +W SE L+ + N+++K D + G
Sbjct: 540 ERQFFVKWQGMSYWHCSWVSELQLE---LHCQVMFRNYQRKNDMDEPPSGDFGGDEEKSR 596
Query: 354 KVSPEDVEYFNCQQELASE-LNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPE 412
K +D ++ ++ + ++ ++ R++ K
Sbjct: 597 KRKNKDPKFAEMEERFYRYGIKPEWMMIHRILNHSVDKK-----------------GHVH 639
Query: 413 YLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNN----SKTIPTRECKALK----QR 464
YL KW LPY + SWE E + + + S+ + + P ++ K +K +R
Sbjct: 640 YLIKWRDLPYDQASWESEDVEIQDYDLFKQSYWNHRELMRGEEGRPGKKLKKVKLRKLER 699
Query: 465 PR-------FVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTI 517
P V ++QP YL L YQ+EGLNWL SW + ILADEMGLGKT+
Sbjct: 700 PPETPTVDPTVKYERQPEYLDATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTV 759
Query: 518 QTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREY 577
QT FL L+ + GPFL+ PLST+ +W+REFE+WAP++ VV Y+GD SR IRE
Sbjct: 760 QTAVFLYSLYKEGHSKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIREN 819
Query: 578 EWIH-----------SQTKR---LKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLK 623
E+ S+ K+ +KF+ L+T+YE++ D +LGSI+WA L VDEAHRLK
Sbjct: 820 EFSFEDNAIRGGKKASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLK 879
Query: 624 NDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGK-GR 682
N+ S ++ L + H+LL+TGTPLQN+L+EL+ LL+F+ PE+F E F E+ +
Sbjct: 880 NNQSKFFRVLNGYSLQHKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAK 939
Query: 683 ENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAK 742
E+ + LH +L P +LRR+K DV K++P+K E I+RVE+S +QK+YYK+ILTRN++AL
Sbjct: 940 EDQIKKLHDMLGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNA 999
Query: 743 GTRGSTSGFLNIVMELKKCCNHCYL--IKPPEENERENGQEILLSLIRSSGKLILLDKLL 800
G+ LN+VM+LKKCCNH YL + E + NG +LIR+SGKL+LL K+L
Sbjct: 1000 RGGGNQVSLLNVVMDLKKCCNHPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKML 1059
Query: 801 TRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSED 860
L+E G+RVLIFSQM +MLD+L ++L + Y ++R+DG I G +R++A+D FNA G++
Sbjct: 1060 KNLKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQ 1119
Query: 861 FCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGT 920
FCFLLSTRAGGLGINLA+ADTV+I+DSDWNP ND+QA +RAHRIGQ K+V IYR VT+ +
Sbjct: 1120 FCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRAS 1179
Query: 921 VEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLF 980
VEE I + AKKKM+L HLV+ R L + +G +K+EL ILKFG E+LF
Sbjct: 1180 VEERITQVAKKKMMLTHLVV-------RPGLGSKTG-----SMSKQELDDILKFGTEELF 1227
Query: 981 KE---------LEGEESEPQEMDIDEILRLAETRENEVSTS---ATDELLSQFKVANFAT 1028
K+ EGE+S D I RL + ++E + +E LS FKVA +
Sbjct: 1228 KDEATDGGGDNKEGEDSSVIHYDDKAIERLLDRNQDETEDTELQGMNEYLSSFKVAQYVV 1287
Query: 1029 ME----DEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTND 1084
E +EEE+E K + + P+ K + Q++ + L + + K+ ND
Sbjct: 1288 REEEMGEEEEVEREIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYND 1347
Query: 1085 SD------SDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDL----------- 1127
D +S Q+ S ASE ED D+ + RR + +R D
Sbjct: 1348 GSQEDRDWQDDQSDNQSDYSVASEEGDEDFDERSEAPRRPSRKGLRNDKDKPLPPLLARV 1407
Query: 1128 -----VEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCV 1182
V GF + + F+ A ++G+P +DA V DL+ E + V
Sbjct: 1408 GGNIEVLGFNARQRKAFLNAIMRYGMP-------PQDAFTTQWLVRDLRGKSEKEFKAYV 1460
Query: 1183 SAMQEYEEQLKENASEGKGPG-KRRGPTIKISGVQVNVKSIIQHE-EEFEMLH------- 1233
S + + + +E G R G + + ++ V S+I+ + +EFE ++
Sbjct: 1461 SLFMRHLCEPGADGAETFADGVPREGLSRQHVLTRIGVMSLIRKKVQEFEHVNGRWSMPE 1520
Query: 1234 ---------KSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELI 1284
S P P K T + +D + I E+ E I
Sbjct: 1521 LAEVEENKKMSQPGSPSPKTPTPSTPGDTQPNTPAPVPPAEDG---IKIEENSLKEEESI 1577
Query: 1285 KTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKP 1344
+ + E+K T +E + P E + V E + K K
Sbjct: 1578 EGEKEVKSTAPETAIECTQAP----------------APASEDEKVVVEPPEGEEKVEKA 1621
Query: 1345 RVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEKQ 1404
VK+ + P E P+ + + + E L ++ K++KKE +E KE
Sbjct: 1622 EVKERTEEPMETE--------PKGAADVEKVEEKSAIDLTPIVVEDKEEKKEEEEKKEVM 1673
Query: 1405 M---SSRKDKEGDKERKKSKDK 1423
+ + KD +K++K K +
Sbjct: 1674 LQNGETPKDLNDEKQKKNIKQR 1695
Score = 43.5 bits (101), Expect = 0.002
Identities = 35/141 (24%), Positives = 62/141 (43%), Gaps = 6/141 (4%)
Query: 1340 KKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKE 1399
KK+KP+ ++ K+P+ K + + R + S EG + E+ ++ + +
Sbjct: 53 KKKKPKKPRDPKIPKSKRQKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTP 112
Query: 1400 NKEKQMSSRKDKEGDKERKKSKDK-KEKPKSGDAKSSSKSKRSQGPVHITAGSEPVPIGE 1458
K+K K K G K+ KKSK K KE+ + D SK +S + G E +
Sbjct: 113 GKKK-----KKKLGPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLLEDWGMEDIDHVF 167
Query: 1459 DEDDDLDQETFSICKERMRPV 1479
E+D + + +RP+
Sbjct: 168 SEEDYRTLTNYKAFSQFVRPL 188
Score = 40.8 bits (94), Expect = 0.012
Identities = 44/178 (24%), Positives = 71/178 (39%), Gaps = 36/178 (20%)
Query: 47 SGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDV 106
SG GS S S+ S E ++ ++ P E E+ S+ E KK + P
Sbjct: 3 SGLGSPSPCSAGSEEEDMDALLNNSLPPPHPENEEDPEEDLSETETPKLKKKKKPKKPRD 62
Query: 107 YGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSA 166
+ +S R ++E R + + S G E E+E+E +
Sbjct: 63 PKIPKSKRQKKE--RMLLCRQLGDSSGEGP-----------------EFVEEEEEVALRS 103
Query: 167 ESE-----PEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPK 219
+SE P +KK K P K+ K + KRK+++ ++DDDD + PK
Sbjct: 104 DSEGSDYTPGKKKKKKLGP------------KKEKKSKSKRKEEEEEEDDDDDSKEPK 149
Score = 37.7 bits (86), Expect = 0.10
Identities = 67/303 (22%), Positives = 120/303 (39%), Gaps = 41/303 (13%)
Query: 1052 RKKVEEEERQK---------ELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASE 1102
RKKV+E E E+EE + + S + K T + DT+ A A +
Sbjct: 1503 RKKVQEFEHVNGRWSMPELAEVEENKKMSQPGSPSPKTPTPSTPGDTQPNTPAPVPPAED 1562
Query: 1103 S--------ETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLE 1154
+ E+S + +K + P + + +E + + + +E+ E
Sbjct: 1563 GIKIEENSLKEEESIEGEKEVKSTAPETAIECTQAPAPASEDEKVVVEPPEGEEKVEKAE 1622
Query: 1155 CIARDAELVD---KSVADLKRLGELIHNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIK 1211
R E ++ K AD++++ E + E +E+ KE E K + G T K
Sbjct: 1623 VKERTEEPMETEPKGAADVEKVEEKSAIDLTPIVVEDKEEKKEE-EEKKEVMLQNGETPK 1681
Query: 1212 ISGVQVNVKSIIQH------EEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVED 1265
+ K+I Q + F LH + E++ +T + +++ W
Sbjct: 1682 DLNDEKQKKNIKQRFMFNIADGGFTELHS---LWQNEERAATVTKKT----YEI-WHRRH 1733
Query: 1266 DSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYL---LKLLR 1322
D LL GI HGY W+ I+ DP + ++ E ++ G L+ + +L KLL
Sbjct: 1734 DYWLLAGIINHGYARWQDIQNDPRYAILNEPFKGEMNR---GNFLEIKNKFLARRFKLLE 1790
Query: 1323 KGL 1325
+ L
Sbjct: 1791 QAL 1793
Score = 36.6 bits (83), Expect = 0.23
Identities = 31/147 (21%), Positives = 66/147 (44%), Gaps = 16/147 (10%)
Query: 113 NRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQE-----KWKQEPSE---------D 158
N S P N ++ SE+ +PK + +++ KK K K++ E D
Sbjct: 25 NNSLPPPHPENEEDPEEDLSETETPKLKKKKKPKKPRDPKIPKSKRQKKERMLLCRQLGD 84
Query: 159 EQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKK--QPKTQRGKRKKQDSSDEDDDDDE 216
+G E E+ +++ T K + KK K ++ K K+++ +E+DDDD+
Sbjct: 85 SSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEEEEEEDDDDD 144
Query: 217 APKRQTRRRAAKNVSYKEDDDFETDSD 243
+ + ++ + ++ ++ D ++ D
Sbjct: 145 SKEPKSSAQLLEDWGMEDIDHVFSEED 171
Score = 32.3 bits (72), Expect = 4.3
Identities = 11/24 (45%), Positives = 17/24 (70%)
Query: 302 EGEIQYLIKWKGWSYIHSTWESEE 325
+G + YLIKW+ Y ++WESE+
Sbjct: 635 KGHVHYLIKWRDLPYDQASWESED 658
Score = 31.2 bits (69), Expect = 9.7
Identities = 37/178 (20%), Positives = 67/178 (37%), Gaps = 38/178 (21%)
Query: 157 EDEQEQGTSAESEPEQKKVKARRPVPRRTVPKP-----RVKKQPKTQRGKRKKQDSSDED 211
E+ ++ S E E E K + P P +V +P K +K + +
Sbjct: 1568 ENSLKEEESIEGEKEVKSTAPETAIECTQAPAPASEDEKVVVEPPEGEEKVEKAEVKERT 1627
Query: 212 DDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRL 271
++ E T + A +V E E + DL + E +E+++ E E +L
Sbjct: 1628 EEPME-----TEPKGAADVEKVE----EKSAIDLTPIVVEDKEEKKEEEEKKEVMLQ--- 1675
Query: 272 GKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWK----GWSYIHSTWESEE 325
NG+ D + EK + I+ + G++ +HS W++EE
Sbjct: 1676 -----------------NGETPKDLNDEKQKKNIKQRFMFNIADGGFTELHSLWQNEE 1716
>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
[Homo sapiens]
Length = 2000
Score = 581 bits (1497), Expect = e-165
Identities = 416/1218 (34%), Positives = 638/1218 (52%), Gaps = 142/1218 (11%)
Query: 304 EIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYF 363
E ++ +KW G SY H +W E L+ + L N+++K D + P ++Y
Sbjct: 547 EREFFVKWVGLSYWHCSWAKELQLE---IFHLVMYRNYQRKNDMDE-------PPPLDYG 596
Query: 364 NCQQELASELNK----QYQIVERV---IAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCK 416
+ + + S+ K Y +E +K T+ + + +K YL K
Sbjct: 597 SGEDDGKSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKK----GNYHYLVK 652
Query: 417 WMGLPYSECSWEDEALIGKKFQNCIDSF--HSRNNSKTIPTRECKALKQRPRF------- 467
W LPY + +WE++ + +++ S+ H P + K K++
Sbjct: 653 WRDLPYDQSTWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPS 712
Query: 468 -------VALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTI 520
V + QP ++ L YQLEGLNWL SW + ILADEMGLGKTIQTI
Sbjct: 713 SPTNDPTVKYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTI 772
Query: 521 SFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWI 580
FL L+ + GPFL+ PLST+ +W+REF++WAP+ VV Y GD SR IRE E+
Sbjct: 773 VFLYSLYKEGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFS 832
Query: 581 HSQTK--------------RLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDD 626
++KF+ L+T+YE++ D+ LGSI WA L VDEAHRLKN+
Sbjct: 833 FEDNAIKGGKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQ 892
Query: 627 SLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGK-GRENG 685
S ++ L +K +H+LL+TGTPLQN+L+EL+ LL+F+ PE+F E F E+ +E+
Sbjct: 893 SKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQ 952
Query: 686 YQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTR 745
+ LH +L P +LRR+K DV K++PAK E I+RVE+S +QK+YYK+ILTRN++AL
Sbjct: 953 IKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGG 1012
Query: 746 GSTSGFLNIVMELKKCCNHCYL--IKPPEENERENGQEILLSLIRSSGKLILLDKLLTRL 803
G+ LNI+M+LKKCCNH YL + E + +G +LI+SSGKL+LL K+L +L
Sbjct: 1013 GNQVSLLNIMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKL 1072
Query: 804 RERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCF 863
+E+G+RVLIFSQM +MLD+L ++L + Y ++R+DG I G +R++A+D FNA G++ FCF
Sbjct: 1073 KEQGHRVLIFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCF 1132
Query: 864 LLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEE 923
LLSTRAGGLGINLA+ADTV+IFDSDWNP ND+QA +RAHRIGQ +V IYR VT+ +VEE
Sbjct: 1133 LLSTRAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEE 1192
Query: 924 EIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFK-E 982
I + AK+KM+L HLV+ R L + +G +K+EL ILKFG E+LFK E
Sbjct: 1193 RITQVAKRKMMLTHLVV-------RPGLGSKAG-----SMSKQELDDILKFGTEELFKDE 1240
Query: 983 LEGEESEPQ----EMDIDEILRLAETRENEVSTSATD-----ELLSQFKVANFATMEDE- 1032
EGE E D + I RL + N+ +T TD E LS FKVA + E++
Sbjct: 1241 NEGENKEEDSSVIHYDNEAIARLLD--RNQDATEDTDVQNMNEYLSSFKVAQYVVREEDK 1298
Query: 1033 -EELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTES 1091
EE+E K + + P+ K + Q++ + L + + K+ ND+ + +
Sbjct: 1299 IEEIEREIIKQEENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDA-AQEDQ 1357
Query: 1092 KRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDL----------------VEGFTDAE 1135
Q++ S SE E ED D+ + +R+ + R +R + V GF +
Sbjct: 1358 DNQSEYSVGSEEEDEDFDERPEGRRQSK-RQLRNEKDKPLPPLLARVGGNIEVLGFNTRQ 1416
Query: 1136 IRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKEN 1195
+ F+ A ++G+P +DA V DL+ E + VS + + +
Sbjct: 1417 RKAFLNAVMRWGMP-------PQDAFTTQWLVRDLRGKTEKEFKAYVSLFMRHLCEPGAD 1469
Query: 1196 ASEGKGPG-KRRGPTIKISGVQVNVKSIIQHE-EEFEMLH-----KSIPVDP--EEKKKY 1246
SE G R G + + ++ V S+++ + +EFE ++ + DP + K+
Sbjct: 1470 GSETFADGVPREGLSRQQVLTRIGVMSLVKKKVQEFEHINGRWSMPELMPDPSADSKRSS 1529
Query: 1247 CLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQ 1306
+ K + E + E I+T E + + ++KP+
Sbjct: 1530 RASSPTKTSPTTPEASATNSPCTSKPATPAPSEKGEGIRTPLEKEEAE-----NQEEKPE 1584
Query: 1307 -----GKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGI 1361
G++++T AD A + GE +L+ RK + E++VP + E
Sbjct: 1585 KNSRIGEKMETEAD----------APSPAPSLGE--RLEPRK--IPLEDEVPGVPGEMEP 1630
Query: 1362 ELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSK 1421
E + + E + G EK P+ Q+ +E E + + R+D +GD+E +
Sbjct: 1631 EPGYRGDREKSATESTPGERGEEK-PL-DGQEHRERPEGETGDLGKREDVKGDRELRPG- 1687
Query: 1422 DKKEKPKSGDAKSSSKSK 1439
+++P+S + K
Sbjct: 1688 -PRDEPRSNGRREEKTEK 1704
Score = 43.1 bits (100), Expect = 0.002
Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 17/142 (11%)
Query: 1338 KLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKEN 1397
K +KR P+ +KENK + ++ + D+ E G +D+ EKS E+
Sbjct: 48 KKRKRGPKKQKENKPGKPRKR--------KKRDSEEEFGSERDEYREKS---------ES 90
Query: 1398 KENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAGSEPVPIG 1457
++ RK + +E+K+ K K+ K GD ++S + +T G E V
Sbjct: 91 GGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQVEQKSSATLLLTWGLEDVEHV 150
Query: 1458 EDEDDDLDQETFSICKERMRPV 1479
E+D + + MRP+
Sbjct: 151 FSEEDYHTLTNYKAFSQFMRPL 172
Score = 36.2 bits (82), Expect = 0.30
Identities = 48/194 (24%), Positives = 83/194 (42%), Gaps = 19/194 (9%)
Query: 12 DSSLHSNASSHSASE----EASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSES- 66
DS S ASS + + EAS ++S S+ + G G + E +E+Q E
Sbjct: 1524 DSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSEKGEGIRTPLEKEEAENQEEKP 1583
Query: 67 ESESAGSKSQPVLPEAKEKPASKKERIADVK-KMWEEYPDVYGVRRSNRSRQEPSRFNIK 125
E S + +A S ER+ K + +E P V G EP +
Sbjct: 1584 EKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVPGVPG-----EMEPEPGYRGDR 1638
Query: 126 EEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRT 185
E++++ S +P RG+ + ++ ++ P E E G + E + K + RP P R
Sbjct: 1639 EKSATES---TPGERGEEKPLDGQEHRERP---EGETGDLGKRE-DVKGDRELRPGP-RD 1690
Query: 186 VPKPRVKKQPKTQR 199
P+ +++ KT++
Sbjct: 1691 EPRSNGRREEKTEK 1704
Score = 33.5 bits (75), Expect = 1.9
Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 381 ERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDE 430
E +AV + G D P R +E E+ KW+GL Y CSW E
Sbjct: 519 EPPVAVPAPQQADGNPDVPP-PRPLQGRSEREFFVKWVGLSYWHCSWAKE 567
Score = 33.1 bits (74), Expect = 2.5
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 1261 WGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYL--- 1317
W D LL GI HGY W+ I+ D + + ++ E +K G L+ + +L
Sbjct: 1740 WHRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANK---GNFLEMKNKFLARR 1796
Query: 1318 LKLLRKGL 1325
KLL + L
Sbjct: 1797 FKLLEQAL 1804
Score = 31.6 bits (70), Expect = 7.4
Identities = 11/24 (45%), Positives = 15/24 (62%)
Query: 302 EGEIQYLIKWKGWSYIHSTWESEE 325
+G YL+KW+ Y STWE +E
Sbjct: 644 KGNYHYLVKWRDLPYDQSTWEEDE 667
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 581 bits (1497), Expect = e-165
Identities = 416/1218 (34%), Positives = 638/1218 (52%), Gaps = 142/1218 (11%)
Query: 304 EIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYF 363
E ++ +KW G SY H +W E L+ + L N+++K D + P ++Y
Sbjct: 606 EREFFVKWVGLSYWHCSWAKELQLE---IFHLVMYRNYQRKNDMDE-------PPPLDYG 655
Query: 364 NCQQELASELNK----QYQIVERV---IAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCK 416
+ + + S+ K Y +E +K T+ + + +K YL K
Sbjct: 656 SGEDDGKSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKK----GNYHYLVK 711
Query: 417 WMGLPYSECSWEDEALIGKKFQNCIDSF--HSRNNSKTIPTRECKALKQRPRF------- 467
W LPY + +WE++ + +++ S+ H P + K K++
Sbjct: 712 WRDLPYDQSTWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPS 771
Query: 468 -------VALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTI 520
V + QP ++ L YQLEGLNWL SW + ILADEMGLGKTIQTI
Sbjct: 772 SPTNDPTVKYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTI 831
Query: 521 SFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWI 580
FL L+ + GPFL+ PLST+ +W+REF++WAP+ VV Y GD SR IRE E+
Sbjct: 832 VFLYSLYKEGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFS 891
Query: 581 HSQTK--------------RLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDD 626
++KF+ L+T+YE++ D+ LGSI WA L VDEAHRLKN+
Sbjct: 892 FEDNAIKGGKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQ 951
Query: 627 SLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGK-GRENG 685
S ++ L +K +H+LL+TGTPLQN+L+EL+ LL+F+ PE+F E F E+ +E+
Sbjct: 952 SKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQ 1011
Query: 686 YQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTR 745
+ LH +L P +LRR+K DV K++PAK E I+RVE+S +QK+YYK+ILTRN++AL
Sbjct: 1012 IKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGG 1071
Query: 746 GSTSGFLNIVMELKKCCNHCYL--IKPPEENERENGQEILLSLIRSSGKLILLDKLLTRL 803
G+ LNI+M+LKKCCNH YL + E + +G +LI+SSGKL+LL K+L +L
Sbjct: 1072 GNQVSLLNIMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKL 1131
Query: 804 RERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCF 863
+E+G+RVLIFSQM +MLD+L ++L + Y ++R+DG I G +R++A+D FNA G++ FCF
Sbjct: 1132 KEQGHRVLIFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCF 1191
Query: 864 LLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEE 923
LLSTRAGGLGINLA+ADTV+IFDSDWNP ND+QA +RAHRIGQ +V IYR VT+ +VEE
Sbjct: 1192 LLSTRAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEE 1251
Query: 924 EIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFK-E 982
I + AK+KM+L HLV+ R L + +G +K+EL ILKFG E+LFK E
Sbjct: 1252 RITQVAKRKMMLTHLVV-------RPGLGSKAG-----SMSKQELDDILKFGTEELFKDE 1299
Query: 983 LEGEESEPQ----EMDIDEILRLAETRENEVSTSATD-----ELLSQFKVANFATMEDE- 1032
EGE E D + I RL + N+ +T TD E LS FKVA + E++
Sbjct: 1300 NEGENKEEDSSVIHYDNEAIARLLD--RNQDATEDTDVQNMNEYLSSFKVAQYVVREEDK 1357
Query: 1033 -EELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTES 1091
EE+E K + + P+ K + Q++ + L + + K+ ND+ + +
Sbjct: 1358 IEEIEREIIKQEENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDA-AQEDQ 1416
Query: 1092 KRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDL----------------VEGFTDAE 1135
Q++ S SE E ED D+ + +R+ + R +R + V GF +
Sbjct: 1417 DNQSEYSVGSEEEDEDFDERPEGRRQSK-RQLRNEKDKPLPPLLARVGGNIEVLGFNTRQ 1475
Query: 1136 IRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKEN 1195
+ F+ A ++G+P +DA V DL+ E + VS + + +
Sbjct: 1476 RKAFLNAVMRWGMP-------PQDAFTTQWLVRDLRGKTEKEFKAYVSLFMRHLCEPGAD 1528
Query: 1196 ASEGKGPG-KRRGPTIKISGVQVNVKSIIQHE-EEFEMLH-----KSIPVDP--EEKKKY 1246
SE G R G + + ++ V S+++ + +EFE ++ + DP + K+
Sbjct: 1529 GSETFADGVPREGLSRQQVLTRIGVMSLVKKKVQEFEHINGRWSMPELMPDPSADSKRSS 1588
Query: 1247 CLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQ 1306
+ K + E + E I+T E + + ++KP+
Sbjct: 1589 RASSPTKTSPTTPEASATNSPCTSKPATPAPSEKGEGIRTPLEKEEAE-----NQEEKPE 1643
Query: 1307 -----GKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGI 1361
G++++T AD A + GE +L+ RK + E++VP + E
Sbjct: 1644 KNSRIGEKMETEAD----------APSPAPSLGE--RLEPRK--IPLEDEVPGVPGEMEP 1689
Query: 1362 ELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSK 1421
E + + E + G EK P+ Q+ +E E + + R+D +GD+E +
Sbjct: 1690 EPGYRGDREKSATESTPGERGEEK-PL-DGQEHRERPEGETGDLGKREDVKGDRELRPG- 1746
Query: 1422 DKKEKPKSGDAKSSSKSK 1439
+++P+S + K
Sbjct: 1747 -PRDEPRSNGRREEKTEK 1763
Score = 43.1 bits (100), Expect = 0.002
Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 17/142 (11%)
Query: 1338 KLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKEN 1397
K +KR P+ +KENK + ++ + D+ E G +D+ EKS E+
Sbjct: 107 KKRKRGPKKQKENKPGKPRKR--------KKRDSEEEFGSERDEYREKS---------ES 149
Query: 1398 KENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAGSEPVPIG 1457
++ RK + +E+K+ K K+ K GD ++S + +T G E V
Sbjct: 150 GGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQVEQKSSATLLLTWGLEDVEHV 209
Query: 1458 EDEDDDLDQETFSICKERMRPV 1479
E+D + + MRP+
Sbjct: 210 FSEEDYHTLTNYKAFSQFMRPL 231
Score = 36.2 bits (82), Expect = 0.30
Identities = 48/194 (24%), Positives = 83/194 (42%), Gaps = 19/194 (9%)
Query: 12 DSSLHSNASSHSASE----EASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSES- 66
DS S ASS + + EAS ++S S+ + G G + E +E+Q E
Sbjct: 1583 DSKRSSRASSPTKTSPTTPEASATNSPCTSKPATPAPSEKGEGIRTPLEKEEAENQEEKP 1642
Query: 67 ESESAGSKSQPVLPEAKEKPASKKERIADVK-KMWEEYPDVYGVRRSNRSRQEPSRFNIK 125
E S + +A S ER+ K + +E P V G EP +
Sbjct: 1643 EKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVPGVPG-----EMEPEPGYRGDR 1697
Query: 126 EEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRT 185
E++++ S +P RG+ + ++ ++ P E E G + E + K + RP P R
Sbjct: 1698 EKSATES---TPGERGEEKPLDGQEHRERP---EGETGDLGKRE-DVKGDRELRPGP-RD 1749
Query: 186 VPKPRVKKQPKTQR 199
P+ +++ KT++
Sbjct: 1750 EPRSNGRREEKTEK 1763
Score = 33.5 bits (75), Expect = 1.9
Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 381 ERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDE 430
E +AV + G D P R +E E+ KW+GL Y CSW E
Sbjct: 578 EPPVAVPAPQQADGNPDVPP-PRPLQGRSEREFFVKWVGLSYWHCSWAKE 626
Score = 33.1 bits (74), Expect = 2.5
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 1261 WGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYL--- 1317
W D LL GI HGY W+ I+ D + + ++ E +K G L+ + +L
Sbjct: 1799 WHRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANK---GNFLEMKNKFLARR 1855
Query: 1318 LKLLRKGL 1325
KLL + L
Sbjct: 1856 FKLLEQAL 1863
Score = 32.7 bits (73), Expect = 3.3
Identities = 39/174 (22%), Positives = 63/174 (36%), Gaps = 10/174 (5%)
Query: 9 QEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESES 68
+EE+ + E A D E G PG G + +S
Sbjct: 20 EEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRGPGHDRGRDRHSPPGCHLFPPPPPP 79
Query: 69 ESAGSKSQPVLPEAKE------KPASKKERIADVKKMWEEYPDVYGVRRSNRSRQE--PS 120
P P K+ K+R KK E P R+ S +E
Sbjct: 80 PPPLPPPPPPPPPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSE 139
Query: 121 RFNIKEEASSG-SESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQK 173
R +E++ SG SE G+ R +R+ K +EK +++ ++ +G + + EQK
Sbjct: 140 RDEYREKSESGGSEYGTGPGRKRRR-KHREKKEKKTKRRKKGEGDGGQKQVEQK 192
Score = 31.6 bits (70), Expect = 7.4
Identities = 11/24 (45%), Positives = 15/24 (62%)
Query: 302 EGEIQYLIKWKGWSYIHSTWESEE 325
+G YL+KW+ Y STWE +E
Sbjct: 703 KGNYHYLVKWRDLPYDQSTWEEDE 726
>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
[Homo sapiens]
Length = 1966
Score = 577 bits (1487), Expect = e-164
Identities = 374/1000 (37%), Positives = 556/1000 (55%), Gaps = 107/1000 (10%)
Query: 304 EIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYF 363
E ++ +KW G SY H +W E L+ + L N+++K D + P ++Y
Sbjct: 547 EREFFVKWVGLSYWHCSWAKELQLE---IFHLVMYRNYQRKNDMDE-------PPPLDYG 596
Query: 364 NCQQELASELNK----QYQIVERV---IAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCK 416
+ + + S+ K Y +E +K T+ + + +K YL K
Sbjct: 597 SGEDDGKSDKRKVKDPHYAEMEEKYYRFGIKPEWMTVHRIINHSVDKK----GNYHYLVK 652
Query: 417 WMGLPYSECSWEDEALIGKKFQNCIDSF--HSRNNSKTIPTRECKALKQRPRF------- 467
W LPY + +WE++ + +++ S+ H P + K K++
Sbjct: 653 WRDLPYDQSTWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPS 712
Query: 468 -------VALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTI 520
V + QP ++ L YQLEGLNWL SW + ILADEMGLGKTIQTI
Sbjct: 713 SPTNDPTVKYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTI 772
Query: 521 SFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWI 580
FL L+ + GPFL+ PLST+ +W+REF++WAP+ VV Y GD SR IRE E+
Sbjct: 773 VFLYSLYKEGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFS 832
Query: 581 HSQTK--------------RLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDD 626
++KF+ L+T+YE++ D+ LGSI WA L VDEAHRLKN+
Sbjct: 833 FEDNAIKGGKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQ 892
Query: 627 SLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGK-GRENG 685
S ++ L +K +H+LL+TGTPLQN+L+EL+ LL+F+ PE+F E F E+ +E+
Sbjct: 893 SKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQ 952
Query: 686 YQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTR 745
+ LH +L P +LRR+K DV K++PAK E I+RVE+S +QK+YYK+ILTRN++AL
Sbjct: 953 IKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGG 1012
Query: 746 GSTSGFLNIVMELKKCCNHCYL--IKPPEENERENGQEILLSLIRSSGKLILLDKLLTRL 803
G+ LNI+M+LKKCCNH YL + E + +G +LI+SSGKL+LL K+L +L
Sbjct: 1013 GNQVSLLNIMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKL 1072
Query: 804 RERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCF 863
+E+G+RVLIFSQM +MLD+L ++L + Y ++R+DG I G +R++A+D FNA G++ FCF
Sbjct: 1073 KEQGHRVLIFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCF 1132
Query: 864 LLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEE 923
LLSTRAGGLGINLA+ADTV+IFDSDWNP ND+QA +RAHRIGQ +V IYR VT+ +VEE
Sbjct: 1133 LLSTRAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEE 1192
Query: 924 EIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFK-E 982
I + AK+KM+L HLV+ R L + +G +K+EL ILKFG E+LFK E
Sbjct: 1193 RITQVAKRKMMLTHLVV-------RPGLGSKAG-----SMSKQELDDILKFGTEELFKDE 1240
Query: 983 LEGEESEPQ----EMDIDEILRLAETRENEVSTSATD-----ELLSQFKVANFATMEDE- 1032
EGE E D + I RL + N+ +T TD E LS FKVA + E++
Sbjct: 1241 NEGENKEEDSSVIHYDNEAIARLLD--RNQDATEDTDVQNMNEYLSSFKVAQYVVREEDK 1298
Query: 1033 -EELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTES 1091
EE+E K + + P+ K + Q++ + L + + K+ ND+ + +
Sbjct: 1299 IEEIEREIIKQEENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYNDA-AQEDQ 1357
Query: 1092 KRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDL----------------VEGFTDAE 1135
Q++ S SE E ED D+ + +R+ + R +R + V GF +
Sbjct: 1358 DNQSEYSVGSEEEDEDFDERPEGRRQSK-RQLRNEKDKPLPPLLARVGGNIEVLGFNTRQ 1416
Query: 1136 IRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKEN 1195
+ F+ A ++G+P +DA V DL+ E + VS + + +
Sbjct: 1417 RKAFLNAVMRWGMP-------PQDAFTTQWLVRDLRGKTEKEFKAYVSLFMRHLCEPGAD 1469
Query: 1196 ASEGKGPG-KRRGPTIKISGVQVNVKSIIQHE-EEFEMLH 1233
SE G R G + + ++ V S+++ + +EFE ++
Sbjct: 1470 GSETFADGVPREGLSRQQVLTRIGVMSLVKKKVQEFEHIN 1509
Score = 43.1 bits (100), Expect = 0.002
Identities = 35/142 (24%), Positives = 61/142 (42%), Gaps = 17/142 (11%)
Query: 1338 KLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKEN 1397
K +KR P+ +KENK + ++ + D+ E G +D+ EKS E+
Sbjct: 48 KKRKRGPKKQKENKPGKPRKR--------KKRDSEEEFGSERDEYREKS---------ES 90
Query: 1398 KENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAGSEPVPIG 1457
++ RK + +E+K+ K K+ K GD ++S + +T G E V
Sbjct: 91 GGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQVEQKSSATLLLTWGLEDVEHV 150
Query: 1458 EDEDDDLDQETFSICKERMRPV 1479
E+D + + MRP+
Sbjct: 151 FSEEDYHTLTNYKAFSQFMRPL 172
Score = 33.5 bits (75), Expect = 1.9
Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 381 ERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDE 430
E +AV + G D P R +E E+ KW+GL Y CSW E
Sbjct: 519 EPPVAVPAPQQADGNPDVPP-PRPLQGRSEREFFVKWVGLSYWHCSWAKE 567
Score = 33.1 bits (74), Expect = 2.5
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 1261 WGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYL--- 1317
W D LL GI HGY W+ I+ D + + ++ E +K G L+ + +L
Sbjct: 1706 WHRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANK---GNFLEMKNKFLARR 1762
Query: 1318 LKLLRKGL 1325
KLL + L
Sbjct: 1763 FKLLEQAL 1770
Score = 31.6 bits (70), Expect = 7.4
Identities = 11/24 (45%), Positives = 15/24 (62%)
Query: 302 EGEIQYLIKWKGWSYIHSTWESEE 325
+G YL+KW+ Y STWE +E
Sbjct: 644 KGNYHYLVKWRDLPYDQSTWEEDE 667
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 568 bits (1465), Expect = e-161
Identities = 415/1256 (33%), Positives = 619/1256 (49%), Gaps = 197/1256 (15%)
Query: 304 EIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYF 363
E ++ +KW G SY H +W E L+ + N+++K D + P +Y
Sbjct: 508 EREFFVKWAGLSYWHCSWVKELQLELYHTVMYR---NYQRKNDMDE-------PPPFDYG 557
Query: 364 NCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAH---SRKPAPSNEPEYLCKWMGL 420
+ ++ SE K + + + + + H + + YL KW L
Sbjct: 558 SGDEDGKSEKRKNKDPLYAKMEERFYRYGIKPEWMMIHRILNHSFDKKGDVHYLIKWKDL 617
Query: 421 PYSECSWEDEALIGKKFQNCIDSFHSRNN-----SKTIPTRECKALK-------QRPR-- 466
PY +C+WE + + + N ++ +P R K K ++P
Sbjct: 618 PYDQCTWEIDDIDIPYYDNLKQAYWGHRELMLGEDTRLPKRLLKKGKKLRDDKQEKPPDT 677
Query: 467 -----FVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTIS 521
V KQP Y+ L YQLEGLNWL SW + ILADEMGLGKT+QTI
Sbjct: 678 PIVDPTVKFDKQPWYIDSTGGTLHPYQLEGLNWLRFSWAQGTDTILADEMGLGKTVQTIV 737
Query: 522 FLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEW-- 579
FL L+ + GP+L+ PLST+ +W+REFE+WAP+ VV Y GD SR+ IRE E+
Sbjct: 738 FLYSLYKEGHSKGPYLVSAPLSTIINWEREFEMWAPDFYVVTYTGDKESRSVIRENEFSF 797
Query: 580 ----IHSQTK--------RLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDS 627
I S K ++KF+ L+T+YE++ D+ +LGSI WA L VDEAHRLKN+ S
Sbjct: 798 EDNAIRSGKKVFRMKKEVQIKFHVLLTSYELITIDQAILGSIEWACLVVDEAHRLKNNQS 857
Query: 628 LLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGK-GRENGY 686
++ L +K +++LL+TGTPLQN+L+EL+ LL+F+ PE+F E F E+ +E+
Sbjct: 858 KFFRVLNSYKIDYKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQI 917
Query: 687 QSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRG 746
+ LH +L P +LRR+K DV K++PAK E I+RVE+S +QK+YYK+ILTRN++AL G
Sbjct: 918 KKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSQMQKKYYKFILTRNFEALNSKGGG 977
Query: 747 STSGFLNIVMELKKCCNHCYL--IKPPEENERENGQEILLSLIRSSGKLILLDKLLTRLR 804
+ LNI+M+LKKCCNH YL + E NG SL++SSGKL+LL K+L +LR
Sbjct: 978 NQVSLLNIMMDLKKCCNHPYLFPVAAVEAPVLPNGSYDGSSLVKSSGKLMLLQKMLKKLR 1037
Query: 805 ERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFL 864
+ G+RVLIFSQM +MLD+L ++L + Y ++R+DG I G +R++A+D FNA G++ FCFL
Sbjct: 1038 DEGHRVLIFSQMTKMLDLLEDFLEYEGYKYERIDGGITGGLRQEAIDRFNAPGAQQFCFL 1097
Query: 865 LSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEE 924
LSTRAGGLGINLA+ADTV+I+DSDWNP ND+QA +RAHRIGQ K+V IYR VT+ +VEE
Sbjct: 1098 LSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEER 1157
Query: 925 IIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFK-EL 983
I + AK+KM+L HLV+ R L + SG K+EL ILKFG E+LFK ++
Sbjct: 1158 ITQVAKRKMMLTHLVV-------RPGLGSKSG-----SMTKQELDDILKFGTEELFKDDV 1205
Query: 984 EGEESEPQ---------------------------------------------EMDIDEI 998
EG S+ Q + I ++
Sbjct: 1206 EGMMSQGQRPVTPIPDVQSSKGGNLAASAKKKHGSTPPGDNKDVEDSSVIHYDDAAISKL 1265
Query: 999 LRLAETRENEVSTSATDELLSQFKVANFATMEDE--EELEERPHKDWDEIIPEEQRKKVE 1056
L + ++ +E LS FKVA + E++ EE+E K + + P+ K +
Sbjct: 1266 LDRNQDATDDTELQNMNEYLSSFKVAQYVVREEDGVEEVEREIIKQEENVDPDYWEKLLR 1325
Query: 1057 EEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASE----SETEDSDDDK 1112
Q++ + L + + K+ ND+ + + + + SE SE ED D ++
Sbjct: 1326 HHYEQQQEDLARNLGKGKRIRKQVNYNDASQEDQEWQDELSDNQSEYSIGSEDEDEDFEE 1385
Query: 1113 KPKRRGRPRSVRKDL--------------------VEGFTDAEIRRFIKAYKKFGLPLER 1152
+P+ + R R+ L V GF + + F+ A ++G+P
Sbjct: 1386 RPEGQSGRRQSRRQLKSDRDKPLPPLLARVGGNIEVLGFNARQRKAFLNAIMRWGMP--- 1442
Query: 1153 LECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKENASEGKGPG-KRRGPTIK 1211
+DA V DL+ E + VS + + + +E G R G + +
Sbjct: 1443 ----PQDAFNSHWLVRDLRGKSEKEFRAYVSLFMRHLCEPGADGAETFADGVPREGLSRQ 1498
Query: 1212 ISGVQVNVKSIIQHE-EEFEMLHKS------IPVDPEEKKKYCLTCR-------VKAAH- 1256
++ V S+++ + +EFE ++ IP PE KK + AH
Sbjct: 1499 HVLTRIGVMSLVRKKVQEFEHVNGKYSTPDLIPEGPEGKKSGEVISSDPNTPVPASPAHL 1558
Query: 1257 FDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADY 1316
G+ D LG + + P L + LP D+ + ++ A
Sbjct: 1559 LPAPLGLPDKMEAQLGYMDEKDPGAQ----KPRQPLEVQALPAALDRVESEDKHESPA-- 1612
Query: 1317 LLKLLRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEG 1376
+K + R+ R ++ K P E+ PR P +E
Sbjct: 1613 --------------------SKERAREERPEETEKAPPSPEQ------LPREEVLPEKEK 1646
Query: 1377 EVKDDGL-------EKSPMKKKQKKKENKENKEKQMSSRK--DKEGDKERKKSKDK 1423
+ L + S ++ K E KE E Q + K D EG KE KK K K
Sbjct: 1647 ILDKLELSLIHSRGDSSELRPDDTKAEEKEPIETQQNGDKEEDDEGKKEDKKGKFK 1702
Score = 44.7 bits (104), Expect = 8e-04
Identities = 31/92 (33%), Positives = 52/92 (56%), Gaps = 6/92 (6%)
Query: 1340 KKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSE-EGEVKDDGLEKSPMKKKQKKKENK 1398
KK+KP+ KENK +++ E S+ S+N + E + + +G + SP KKK+KK ++K
Sbjct: 49 KKKKPKKLKENKCKGKRKKK--EGSNDELSENEEDLEEKSESEGSDYSPNKKKKKKLKDK 106
Query: 1399 ENKEKQMSSRKDKEGDKERKKSKDKKEKPKSG 1430
+ K+ + RK K+ D++ KE SG
Sbjct: 107 KEKK---AKRKKKDEDEDDNDDGCLKEPKSSG 135
Score = 42.0 bits (97), Expect = 0.005
Identities = 38/130 (29%), Positives = 58/130 (44%), Gaps = 19/130 (14%)
Query: 1346 VKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSP---------MKKKQKKKE 1396
V E ++PRL E +N E E +D GLE + KK+K K+
Sbjct: 5 VGTEEELPRLFAEE---------MENEDEMSEEEDGGLEAFDDFFPVEPVSLPKKKKPKK 55
Query: 1397 NKENKEKQMSSRKDKEGDKERKKSKDKKEKPKS-GDAKSSSKSKRSQGPVHITAGSEPVP 1455
KENK K +K+ D+ + +D +EK +S G S +K K+ + ++
Sbjct: 56 LKENKCKGKRKKKEGSNDELSENEEDLEEKSESEGSDYSPNKKKKKKLKDKKEKKAKRKK 115
Query: 1456 IGEDEDDDLD 1465
EDEDD+ D
Sbjct: 116 KDEDEDDNDD 125
Score = 38.5 bits (88), Expect = 0.061
Identities = 30/119 (25%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Query: 101 EEYPDVYGVRRSNR---SRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQE-KWKQEPS 156
EE P ++ N S +E ++ PK++ ++LK+ + K K++
Sbjct: 9 EELPRLFAEEMENEDEMSEEEDGGLEAFDDFFPVEPVSLPKKKKPKKLKENKCKGKRKKK 68
Query: 157 EDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDD 215
E ++ + E + E+K K ++K + K ++ KRKK+D DEDD+DD
Sbjct: 69 EGSNDELSENEEDLEEKSESEGSDYSPNKKKKKKLKDK-KEKKAKRKKKD-EDEDDNDD 125
Score = 35.8 bits (81), Expect = 0.39
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 22/117 (18%)
Query: 138 KRRGQRQLKKQEKWKQEPSEDEQEQGTSAESE-----PEQKKVKARRPVPRRTVPKPRVK 192
K +G+R KK+E E SE+E++ +ESE P +KK K K + K
Sbjct: 60 KCKGKR--KKKEGSNDELSENEEDLEEKSESEGSDYSPNKKKKK-----------KLKDK 106
Query: 193 KQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMT 249
K+ K +R K+K +D D DD + PK + A + +D D+ +D +T
Sbjct: 107 KEKKAKR-KKKDEDEDDNDDGCLKEPKSSGQLMAEWGL---DDVDYLFSEEDYHTLT 159
Score = 35.0 bits (79), Expect = 0.67
Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 6/68 (8%)
Query: 1261 WGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYL--- 1317
W D LL GI HGY W+ I+ DP + ++ E K G L+ + +L
Sbjct: 1736 WHRRHDYWLLAGIVTHGYARWQDIQNDPRYMILNEPFKSEVHK---GNYLEMKNKFLARR 1792
Query: 1318 LKLLRKGL 1325
KLL + L
Sbjct: 1793 FKLLEQAL 1800
Score = 33.5 bits (75), Expect = 1.9
Identities = 37/179 (20%), Positives = 79/179 (44%), Gaps = 29/179 (16%)
Query: 155 PSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKP--RVKKQPKTQRGKRKKQDSSDEDD 212
P + E + G E +P +K R+P+ + +P RV+ + K + K++ + +
Sbjct: 1566 PDKMEAQLGYMDEKDPGAQK--PRQPLEVQALPAALDRVESEDKHESPASKERAREERPE 1623
Query: 213 DDDEAPKRQTRRRAAKNVSYKED--DDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSR 270
+ ++AP + + + KE D E LI G+ + + D+++ EK
Sbjct: 1624 ETEKAPPSPEQLPREEVLPEKEKILDKLELS---LIHSRGDSSELRPDDTKAEEK----- 1675
Query: 271 LGKKGATGASTTVYAIEANGDPSGDFDTEKDE--GEIQYL--IKWKGWSYIHSTWESEE 325
+ NGD D + +K++ G+ +++ I G++ +H+ W++EE
Sbjct: 1676 -----------EPIETQQNGDKEEDDEGKKEDKKGKFKFMFNIADGGFTELHTLWQNEE 1723
Score = 33.1 bits (74), Expect = 2.5
Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 9/98 (9%)
Query: 228 KNVSYKEDDDFETDSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIE 287
+N K D D E D +G E++ N + + ++ R + G ++ I
Sbjct: 540 RNYQRKNDMD-EPPPFDYGSGDEDGKSEKRKNKDPLYAKMEERFYRYGIKPEWMMIHRIL 598
Query: 288 ANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEE 325
+ FD + G++ YLIKWK Y TWE ++
Sbjct: 599 NHS-----FDKK---GDVHYLIKWKDLPYDQCTWEIDD 628
Score = 31.2 bits (69), Expect = 9.7
Identities = 23/100 (23%), Positives = 47/100 (47%), Gaps = 11/100 (11%)
Query: 1029 MEDEEELEERPH---KDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDS 1085
ME+E+E+ E + +D+ P E + ++++ K+L+E K + +
Sbjct: 19 MENEDEMSEEEDGGLEAFDDFFPVEP-VSLPKKKKPKKLKE-------NKCKGKRKKKEG 70
Query: 1086 DSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRK 1125
+D S+ + SESE D +KK K++ + + +K
Sbjct: 71 SNDELSENEEDLEEKSESEGSDYSPNKKKKKKLKDKKEKK 110
Score = 31.2 bits (69), Expect = 9.7
Identities = 19/88 (21%), Positives = 42/88 (47%), Gaps = 11/88 (12%)
Query: 1024 ANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTN 1083
+N E+EE+LEE+ + + P +++KK +++++K ++ KK +
Sbjct: 71 SNDELSENEEDLEEKSESEGSDYSPNKKKKKKLKDKKEK-----------KAKRKKKDED 119
Query: 1084 DSDSDTESKRQAQRSSASESETEDSDDD 1111
+ D+D ++ + S +E D D
Sbjct: 120 EDDNDDGCLKEPKSSGQLMAEWGLDDVD 147
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 545 bits (1404), Expect = e-154
Identities = 368/1086 (33%), Positives = 563/1086 (51%), Gaps = 148/1086 (13%)
Query: 74 KSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRR--SNRSRQEPSRFNIKEEASSG 131
KS LP +++P KK++ + + E+ +G QE +R ++
Sbjct: 582 KSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGGVDNQELNRNSLDGSQEEK 641
Query: 132 SESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPKPRV 191
+ K + + K+ K K+EP E + + EP++KK K P P+ + K
Sbjct: 642 KKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSS--KKSS 699
Query: 192 KKQP---------KTQRGKRKKQDSSDEDD--------DDDEAPKRQTRR--RAAKNVSY 232
K+P K +GK + ++SD D ++DE P Q RR R K Y
Sbjct: 700 NKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPPPEEDEDPGVQKRRSSRQVKRKRY 759
Query: 233 KEDDDFETDSDDLIEMTGEGVDEQQDNSET------------IEKVLDSRLGKKGATGAS 280
ED +F+ ++ + G D + S++ +EK++ SR KK
Sbjct: 760 TEDLEFKISDEEADDADAAGRDSPSNTSQSEQQESVDAEGPVVEKIMSSRSVKK------ 813
Query: 281 TTVYAIEANGDPSGDFDTEKDEGEI----QYLIKWKGWSYIHSTWESEESLQQQKVKGLK 336
+K+ GE ++ +K+K +SY+H W S E L++ K + +
Sbjct: 814 ------------------QKESGEEVEIEEFYVKYKNFSYLHCQWASIEDLEKDK-RIQQ 854
Query: 337 KLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQT 396
K++ FK K+ + K +L ++ E N Y V+R++ S G+
Sbjct: 855 KIKRFKAKQGQNK-FLSEIEDE-------------LFNPDYVEVDRIMDFARSTDDRGEP 900
Query: 397 DFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTR 456
YL KW LPY + +WE I + + SR
Sbjct: 901 -------------VTHYLVKWCSLPYEDSTWERRQDIDQAKIEEFEKLMSREP------- 940
Query: 457 ECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKT 516
E + +++ P K + + N +LR+YQLEG+NWL +W + ILADEMGLGKT
Sbjct: 941 ETERVERPPADDWKKSESSREYKNNNKLREYQLEGVNWLLFNWYNMRNCILADEMGLGKT 1000
Query: 517 IQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIRE 576
IQ+I+FL Y + ++GPFL++ PLST+ +W+REF W E+NVVVY G SR TI+
Sbjct: 1001 IQSITFL-YEIYLKGIHGPFLVIAPLSTIPNWEREFRTWT-ELNVVVYHGSQASRRTIQL 1058
Query: 577 YEWIHSQTK------RLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLY 630
YE + KF+A+ITT+E++L D L +I W + +DEAHRLKN + L
Sbjct: 1059 YEMYFKDPQGRVIKGSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLL 1118
Query: 631 KTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGR-ENGYQSL 689
+ L H++L+TGTPLQN+++EL+SLLHF+ P +F F ++ G + E Q L
Sbjct: 1119 EGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSRFPSETTFMQEFGDLKTEEQVQKL 1178
Query: 690 HKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGT-RGST 748
+L+P +LRR+K+DVEK+L K E I+ VE++ +QK+YY+ IL +N+ L+KG + +
Sbjct: 1179 QAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFTFLSKGGGQANV 1238
Query: 749 SGFLNIVMELKKCCNHCYLIKPPEENERENGQEI---------LLSLIRSSGKLILLDKL 799
LN +MEL+KCCNH YLI EE E +E L ++I+++GKL+L+DKL
Sbjct: 1239 PNLLNTMMELRKCCNHPYLINGAEEKILEEFKETHNAESPDFQLQAMIQAAGKLVLIDKL 1298
Query: 800 LTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSE 859
L +L+ G+RVLIFSQMVR LDIL +YL + YP++R+DG ++G +R+ A+D F+ S+
Sbjct: 1299 LPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDSD 1358
Query: 860 DFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKG 919
F FLL TRAGGLGINL +ADT +IFDSDWNPQNDLQAQAR HRIGQ K V IYRL+T+
Sbjct: 1359 RFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRN 1418
Query: 920 TVEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNS----NPFNKEELTAILKFG 975
+ E E+ ++A K+ LD V+Q M SGR N+ +K+E+ +L+ G
Sbjct: 1419 SYEREMFDKASLKLGLDKAVLQSM-----------SGRENATNGVQQLSKKEIEDLLRKG 1467
Query: 976 AEDLFKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEEL 1035
A + E E S+ E DID+IL R T ++ S F A+F + ++
Sbjct: 1468 AYGALMDEEDEGSKFCEEDIDQIL----LRRTHTITIESEGKGSTFAKASFVASGNRTDI 1523
Query: 1036 EERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTK---------KAQTNDSD 1086
W + ++ +++ + + PR+R T+ + +D +
Sbjct: 1524 SLDDPNFWQK---WAKKAELDIDALNGRNNLVIDTPRVRKQTRLYSAVKEDELMEFSDLE 1580
Query: 1087 SDTESK 1092
SD+E K
Sbjct: 1581 SDSEEK 1586
Score = 45.8 bits (107), Expect = 4e-04
Identities = 39/150 (26%), Positives = 61/150 (40%), Gaps = 22/150 (14%)
Query: 1328 KGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSP 1387
+ ++ G +E K KK++ + KK+ K P+ P+ P E K K P
Sbjct: 631 RNSLDGSQEEKKKKKRSKAKKDPKEPK----------EPKEKKEPKEP---KTPKAPKIP 677
Query: 1388 MKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHI 1447
+ K+KK + K K +K+ D E K K K K+ +++S K
Sbjct: 678 KEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDK-------- 729
Query: 1448 TAGSEPVPIGEDEDDDLDQETFSICKERMR 1477
T P P EDED + + S +R R
Sbjct: 730 TPPPSPPP-EEDEDPGVQKRRSSRQVKRKR 758
Score = 39.3 bits (90), Expect = 0.036
Identities = 51/192 (26%), Positives = 75/192 (39%), Gaps = 33/192 (17%)
Query: 1288 PELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKPRVK 1347
P +K +P T QL DYL + ++ +KK + K
Sbjct: 558 PSEPFLEKPVPDMTQVSGPNAQLVKSDDYLPSIEQQPQQKK----------------KKK 601
Query: 1348 KENKVPRLKEEHGIELSS-PRHSDNPSEEGEVKDDGLEKSPMKKKQKK--------KENK 1398
K N + G P DN E+ + L+ S +KK+KK KE K
Sbjct: 602 KNNHIVAEDPSKGFGKDDFPGGVDNQ----ELNRNSLDGSQEEKKKKKRSKAKKDPKEPK 657
Query: 1399 ENKE-KQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAGSEPVPIG 1457
E KE K+ K + K K+ K+KK K + KSS KS + +A + V G
Sbjct: 658 EPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKVNKG 717
Query: 1458 E---DEDDDLDQ 1466
+ E+ DLD+
Sbjct: 718 KTEGSENSDLDK 729
Score = 35.8 bits (81), Expect = 0.39
Identities = 45/211 (21%), Positives = 92/211 (43%), Gaps = 17/211 (8%)
Query: 1298 PVETDKKPQGKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKE 1357
P E +K + K+ +T K+ ++ EKK A T + K K+ K +++ LK+
Sbjct: 656 PKEPKEKKEPKEPKTPK--APKIPKEPKEKK-AKTATPKPKSSKKSSNKKPDSEASALKK 712
Query: 1358 E------HGIELSSPRHSDNPSEEGEVKDD-GLEKSPMKKKQKKKENKENKEKQMSSRKD 1410
+ G E S + PS E +D G++K ++ K+K E+ E ++S D
Sbjct: 713 KVNKGKTEGSENSDLDKTPPPSPPPEEDEDPGVQKRRSSRQVKRKRYTEDLEFKIS---D 769
Query: 1411 KEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGP-VHITAGSEPVPIGEDEDDDLDQETF 1469
+E D +D P + +S ++GP V S V ++ ++++ E F
Sbjct: 770 EEADDADAAGRD---SPSNTSQSEQQESVDAEGPVVEKIMSSRSVKKQKESGEEVEIEEF 826
Query: 1470 SICKERMRPVKKALKQLDKPDKGLNVQEQLE 1500
+ + + ++ +K +Q++++
Sbjct: 827 YVKYKNFSYLHCQWASIEDLEKDKRIQQKIK 857
Score = 35.4 bits (80), Expect = 0.51
Identities = 12/36 (33%), Positives = 22/36 (61%)
Query: 1261 WGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKI 1296
W E D LL+G+++HGY + ++ DP L +++
Sbjct: 1786 WDKEADKSLLIGVFKHGYEKYNSMRADPALCFLERV 1821
Score = 33.5 bits (75), Expect = 1.9
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 12/77 (15%)
Query: 7 KSQEEDSSLHSNASSHSASEEAS-----------GSDSGSQSESEQGSDPGSGHGSESNS 55
K +EE++ S EAS G+D+GS+S SE+GS+ E +
Sbjct: 2190 KEEEEETDGSGKESKQECEAEASSVKNELKGVEVGADTGSKSISEKGSEEDEEEKLEDDD 2249
Query: 56 SSESSESQSESESESAG 72
SE S SQ E+ + S G
Sbjct: 2250 KSEES-SQPEAGAVSRG 2265
Score = 31.2 bits (69), Expect = 9.7
Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 10/134 (7%)
Query: 988 SEPQEMDIDEILRLAETRENEVSTSATDELLSQF----KVANFATMEDEEELEERPHKDW 1043
++P+ +D A+ R +TS+ + L F V + A ++DE LE+ K
Sbjct: 2118 NDPELSFLDAHKNFAQNR-GAGNTSSLNPLAVGFVQTPPVISSAHIQDERVLEQAEGKVE 2176
Query: 1044 DEIIPEEQRK---KVEEEERQKELEEIYMLPRIRSSTKKAQTNDSD--SDTESKRQAQRS 1098
+ P + K K EEEE +E +S+ K + + +DT SK +++
Sbjct: 2177 EPENPAAKEKCEGKEEEEETDGSGKESKQECEAEASSVKNELKGVEVGADTGSKSISEKG 2236
Query: 1099 SASESETEDSDDDK 1112
S + E + DDDK
Sbjct: 2237 SEEDEEEKLEDDDK 2250
>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
sapiens]
Length = 2715
Score = 533 bits (1372), Expect = e-151
Identities = 376/1154 (32%), Positives = 586/1154 (50%), Gaps = 175/1154 (15%)
Query: 8 SQEEDSSLHSNA-SSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSES 66
++EE ++L +SH+ E++ G +G + + ++ +PG G+ S + + +
Sbjct: 64 AEEEAATLFPRKMTSHNGMEDSGGGGTGVKKKRKK-KEPGDQEGAAKGSKDREPKPKRKR 122
Query: 67 ESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKE 126
E + +P P ++P KE +E G +++ + R+ KE
Sbjct: 123 EPK------EPKEPRKAKEPKKAKEH--------KEPKQKDGAKKARKPREASGTKEAKE 168
Query: 127 EASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTV 186
+ S + K R + +EQG + P +KK K +R T
Sbjct: 169 KRSCTDSAARTKSR----------------KASKEQGPT----PVEKKKKGKR--KSETT 206
Query: 187 PKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDD-- 244
+ Q T R ++S++ D RQ +RR Y ED DF+ DD
Sbjct: 207 VESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRR-----KYNEDLDFKVVDDDGE 261
Query: 245 LIEMTGEG--------------VDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANG 290
I + G G + +D++ IEK+L AS TV +
Sbjct: 262 TIAVLGAGRTSALSASTLAWQAEEPPEDDANIIEKIL-----------ASKTVQEVHPGE 310
Query: 291 DPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQ 350
P FD E + +K++ +SY+H W + E L++ + +K++ F+ K+ ++K
Sbjct: 311 PP---FDLE------LFYVKYRNFSYLHCKWATMEELEKDP-RIAQKIKRFRNKQAQMKH 360
Query: 351 WLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNE 410
+ D + F N Y V+R++ V AH++ E
Sbjct: 361 IF---TEPDEDLF----------NPDYVEVDRILEV-------------AHTKDAETGEE 394
Query: 411 -PEYLCKWMGLPYSECSWEDEALIG----KKFQNCIDSFHSRNNSKTIPTRECKALKQRP 465
YL KW LPY E +WE E + K+F++ + +P +
Sbjct: 395 VTHYLVKWCSLPYEESTWELEEDVDPAKVKEFESL----------QVLPEIKHVERPASD 444
Query: 466 RFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSY 525
+ L+K Y +LR+YQLEG+NWL +W + ILADEMGLGKTIQ+I+FLS
Sbjct: 445 SWQKLEKSREYKNSN--QLREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSITFLSE 502
Query: 526 LFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTK 585
+F ++GPFLI+ PLST+T+W+REF W E+N +VY G +SR I++YE ++ +
Sbjct: 503 IF-LRGIHGPFLIIAPLSTITNWEREFRTWT-EMNAIVYHGSQISRQMIQQYEMVYRDAQ 560
Query: 586 R------LKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSN 639
KF+ +ITT+E++L D L I+W+ + +DEAHRLKN + L + L
Sbjct: 561 GNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAHRLKNRNCKLLEGLKLMALE 620
Query: 640 HRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGR-ENGYQSLHKVLEPFLL 698
H++L+TGTPLQNS++EL+SLL+F+ P +F F E+ G + E + L +L+P +L
Sbjct: 621 HKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGDLKTEEQVKKLQSILKPMML 680
Query: 699 RRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKG-TRGSTSGFLNIVME 757
RR+K DVEK+L K E I+ VE++ +QK+YY+ IL +N+ L KG + + +N +ME
Sbjct: 681 RRLKDDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLTKGANQHNMPNLINTMME 740
Query: 758 LKKCCNHCYLIKPPEENERENGQEI---------LLSLIRSSGKLILLDKLLTRLRERGN 808
L+KCCNH YLI EE E+ ++ L ++I+++GKL+L+DKLL +L G+
Sbjct: 741 LRKCCNHPYLINGAEEKILEDFRKTHSPDAPDFQLQAMIQAAGKLVLIDKLLPKLIAGGH 800
Query: 809 RVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTR 868
+VLIFSQMVR LDIL +YL + Y ++R+DG ++G +R+ A+D F S+ F FLL TR
Sbjct: 801 KVLIFSQMVRCLDILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTR 860
Query: 869 AGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIER 928
AGGLGINL +ADT +IFDSDWNPQNDLQAQAR HRIGQ K V +YRL+T+ + E E+ ++
Sbjct: 861 AGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDK 920
Query: 929 AKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFKELEGEES 988
A K+ LD V+Q ++ G G + +K E+ +L+ GA + E E S
Sbjct: 921 ASLKLGLDKAVLQDINRKG--------GTNGVQQLSKMEVEDLLRKGAYGALMDEEDEGS 972
Query: 989 EPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELE-ERPH--KDWDE 1045
+ E DID+IL+ R T ++ S F A+F + ++ + P+ + W +
Sbjct: 973 KFCEEDIDQILQ----RRTHTITIQSEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAK 1028
Query: 1046 IIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESET 1105
I + K E+E + PR+R TK + + D E
Sbjct: 1029 IAELDTEAKNEKESL------VIDRPRVRKQTKHYNSFEED------------ELMEFSE 1070
Query: 1106 EDSDDDKKPKRRGR 1119
DSD D++P R R
Sbjct: 1071 LDSDSDERPTRSRR 1084
Score = 46.6 bits (109), Expect = 2e-04
Identities = 45/171 (26%), Positives = 70/171 (40%), Gaps = 28/171 (16%)
Query: 1286 TDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRK------GLEKKGAVTGGEEAKL 1339
TD E K+ D V + PQ K L T + L + G+E G G + K
Sbjct: 42 TDQEEKIED----VASHCLPQ-KDLYTAEEEAATLFPRKMTSHNGMEDSGGGGTGVKKKR 96
Query: 1340 KKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKE 1399
KK++P ++ G S P + E K+ K P K K+ KK +
Sbjct: 97 KKKEPG-----------DQEGAAKGSKDREPKPKRKREPKEP---KEPRKAKEPKKAKEH 142
Query: 1400 NKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRS---QGPVHI 1447
+ KQ K +E +K+ KEK D+ + +KS+++ QGP +
Sbjct: 143 KEPKQKDGAKKARKPREASGTKEAKEKRSCTDSAARTKSRKASKEQGPTPV 193
Score = 38.9 bits (89), Expect = 0.046
Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 18/128 (14%)
Query: 1326 EKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEK 1385
+++GA G ++ ++ KP+ K+E K P+ PR + P + E K+ +K
Sbjct: 103 DQEGAAKGSKD---REPKPKRKREPKEPK----------EPRKAKEPKKAKEHKEP-KQK 148
Query: 1386 SPMKKKQKKKE---NKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQ 1442
KK +K +E KE KEK+ S K RK SK++ P K KS+ +
Sbjct: 149 DGAKKARKPREASGTKEAKEKR-SCTDSAARTKSRKASKEQGPTPVEKKKKGKRKSETTV 207
Query: 1443 GPVHITAG 1450
+ + G
Sbjct: 208 ESLELDQG 215
Score = 38.9 bits (89), Expect = 0.046
Identities = 28/112 (25%), Positives = 56/112 (50%), Gaps = 8/112 (7%)
Query: 1033 EELEERPHKDWDEIIPEEQRK-------KVEEEERQKELEEIYMLPRIRSSTKKAQTNDS 1085
++ E +P + + P+E RK K +E +QK+ + PR S TK+A+ S
Sbjct: 112 KDREPKPKRKREPKEPKEPRKAKEPKKAKEHKEPKQKDGAKKARKPREASGTKEAKEKRS 171
Query: 1086 DSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIR 1137
+D+ ++ +++++S + T + KK KR+ +L +G T+ +R
Sbjct: 172 CTDSAARTKSRKASKEQGPTP-VEKKKKGKRKSETTVESLELDQGLTNPSLR 222
Score = 37.7 bits (86), Expect = 0.10
Identities = 13/36 (36%), Positives = 22/36 (61%)
Query: 1261 WGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKI 1296
W E D LL+G+++HGY + ++ DP L +K+
Sbjct: 1277 WDAEADKSLLIGVFKHGYERYNAMRADPALCFLEKV 1312
>gi|114326455 chromodomain helicase DNA binding protein 8 [Homo
sapiens]
Length = 2302
Score = 531 bits (1367), Expect = e-150
Identities = 378/1135 (33%), Positives = 584/1135 (51%), Gaps = 138/1135 (12%)
Query: 20 SSHSASEEASGSDSGSQSESEQGSDPGSG--HGSESNSSSESSESQSESESESAGSKSQP 77
SS AS S S SE S P S H E+ + + + E A
Sbjct: 129 SSQGASSGLSVVKVLSASEVAALSSPASSAPHSGGKTGMEENRRLEHQKKQEKANRIVAE 188
Query: 78 VLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSE-SGS 136
+ A+ + R+ + ++ P+ G ++ R++ + +KEE S+ SG+
Sbjct: 189 AIARARARGEQNIPRVLNEDELPSVRPEEEGEKKR---RKKSAGERLKEEKPKKSKTSGA 245
Query: 137 PKRRGQRQL--------KKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVPK 188
K +G+ +L KK+++ + D + + E E+ ++ RR
Sbjct: 246 SKTKGKSKLNTITPVVGKKRKRNTSSDNSDVEVMPAQSPREDEESSIQKRRS-------N 298
Query: 189 PRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEM 248
+VK++ T+ K D +E++ D P K + E D + L M
Sbjct: 299 RQVKRKKYTEDLDIKITDDEEEEEVDVTGP--------IKPEPILPEPVQEPDGETLPSM 350
Query: 249 TGEGVDEQQDNSETIEKVLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYL 308
+ ++++ ++KVL R+ KK PSG + TE +E +
Sbjct: 351 QFFVENPSEEDAAIVDKVLSMRIVKKEL---------------PSGQY-TEAEE----FF 390
Query: 309 IKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQE 368
+K+K +SY+H W + L++ K + +KL+ FK K +++ + ED E FN
Sbjct: 391 VKYKNYSYLHCEWATISQLEKDK-RIHQKLKRFKTKMAQMRHFFH----EDEEPFN---- 441
Query: 369 LASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNEPE--YLCKWMGLPYSECS 426
Y V+R++ S + EP YL KW LPY + +
Sbjct: 442 ------PDYVEVDRILDESHSIDK--------------DNGEPVIYYLVKWCSLPYEDST 481
Query: 427 WEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALK-QRPRFVALKKQPAYLGGENL-EL 484
WE + +D R K I +R + + RP+ A KK +N +L
Sbjct: 482 WE--------LKEDVDEGKIRE-FKRIQSRHPELKRVNRPQASAWKKLELSHEYKNRNQL 532
Query: 485 RDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLST 544
R+YQLEG+NWL +W + ILADEMGLGKTIQ+I+FL +++ ++GPFL++ PLST
Sbjct: 533 REYQLEGVNWLLFNWYNRQNCILADEMGLGKTIQSIAFLQEVYNVG-IHGPFLVIAPLST 591
Query: 545 LTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTK------RLKFNALITTYEI 598
+T+W+REF W E+N +VY G L SR I++YE ++ KF+ALITT+E+
Sbjct: 592 ITNWEREFNTWT-EMNTIVYHGSLASRQMIQQYEMYCKDSRGRLIPGAYKFDALITTFEM 650
Query: 599 LLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWS 658
+L D L I W + +DEAHRLKN + L +L H++L+TGTPLQN+++EL+S
Sbjct: 651 ILSDCPELREIEWRCVIIDEAHRLKNRNCKLLDSLKHMDLEHKVLLTGTPLQNTVEELFS 710
Query: 659 LLHFIMPEKFEFWEDFEEDHGKGR-ENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQIL 717
LLHF+ P +F +F +D G + E Q L +L+P +LRR+K+DVEK+L K E I+
Sbjct: 711 LLHFLEPSQFPSESEFLKDFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKQETII 770
Query: 718 RVEMSALQKQYYKWILTRNYKALAKGTRGSTS--GFLNIVMELKKCCNHCYLIKPPEENE 775
VE++ +QK+YY+ IL +N+ L+KG G T+ LN +MEL+KCCNH YLI EE
Sbjct: 771 EVELTNIQKKYYRAILEKNFSFLSKGA-GHTNMPNLLNTMMELRKCCNHPYLINGAEEKI 829
Query: 776 RENGQEI---------LLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEY 826
+E L +++RS+GKL+L+DKLL +L+ G++VLIFSQMVR LDIL +Y
Sbjct: 830 LTEFREACHIIPHDFHLQAMVRSAGKLVLIDKLLPKLKAGGHKVLIFSQMVRCLDILEDY 889
Query: 827 LTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFD 886
L + Y ++R+DG ++G +R+ A+D F+ S+ F FLL TRAGGLGINL +ADT +IFD
Sbjct: 890 LIQRRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFD 949
Query: 887 SDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTT 946
SDWNPQNDLQAQAR HRIGQ K V +YRL+T+ + E E+ ++A K+ LD V+Q M +
Sbjct: 950 SDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQSM--S 1007
Query: 947 GRTILENNSGRSNSNPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRE 1006
GR + + F+K+E+ +L+ GA E + E S+ E DID+IL R
Sbjct: 1008 GR-----DGNITGIQQFSKKEIEDLLRKGAYAAIMEEDDEGSKFCEEDIDQIL----LRR 1058
Query: 1007 NEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEE 1066
T ++ S F A+F E+ ++ W + ++ ++ + +
Sbjct: 1059 TTTITIESEGKGSTFAKASFVASENRTDISLDDPNFWQK---WAKKADLDMDLLNSKNNL 1115
Query: 1067 IYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPR 1121
+ PR+R T+ T D E +S+DD++P+ R R
Sbjct: 1116 VIDTPRVRKQTRHFSTLKDD------------DLVEFSDLESEDDERPRSRRHDR 1158
Score = 35.8 bits (81), Expect = 0.39
Identities = 13/35 (37%), Positives = 21/35 (60%)
Query: 1261 WGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDK 1295
W E D LL+G+++HGY + ++ DP L +K
Sbjct: 1346 WDSEADKSLLIGVFKHGYEKYNTMRADPALCFLEK 1380
Score = 34.7 bits (78), Expect = 0.87
Identities = 33/124 (26%), Positives = 49/124 (39%), Gaps = 21/124 (16%)
Query: 1343 KPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKE 1402
+ R + E +PR+ E EL S R P EEGE KK++KK + KE
Sbjct: 192 RARARGEQNIPRVLNED--ELPSVR----PEEEGE-----------KKRRKKSAGERLKE 234
Query: 1403 KQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDD 1462
++ K K + KSK P G + + S V + P EDE+
Sbjct: 235 EKPKKSKTSGASKTKGKSKLNTITPVVGKKRKRNTSS-DNSDVEVMPAQSP---REDEES 290
Query: 1463 DLDQ 1466
+ +
Sbjct: 291 SIQK 294
Score = 33.1 bits (74), Expect = 2.5
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 30/103 (29%)
Query: 1363 LSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKE----------------------N 1400
LSSP S P G+ G+E++ + QKK+E N
Sbjct: 151 LSSPA-SSAPHSGGKT---GMEENRRLEHQKKQEKANRIVAEAIARARARGEQNIPRVLN 206
Query: 1401 KEKQMSSRKDKEGDKERKK----SKDKKEKPKSGDAKSSSKSK 1439
+++ S R ++EG+K+R+K + K+EKPK +SK+K
Sbjct: 207 EDELPSVRPEEEGEKKRRKKSAGERLKEEKPKKSKTSGASKTK 249
Score = 32.7 bits (73), Expect = 3.3
Identities = 31/151 (20%), Positives = 64/151 (42%), Gaps = 27/151 (17%)
Query: 1323 KGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDG 1382
+G +K+ + GE +LK+ KP+ K + + K + + +P
Sbjct: 218 EGEKKRRKKSAGE--RLKEEKPKKSKTSGASKTKGKSKLNTITP---------------- 259
Query: 1383 LEKSPMKKKQKKKENKENKEKQM----SSRKDKEGD-KERKKSKDKKEKPKSGDAKSSSK 1437
+ KK+K+ + +N + ++ S R+D+E ++R+ ++ K K + D
Sbjct: 260 ----VVGKKRKRNTSSDNSDVEVMPAQSPREDEESSIQKRRSNRQVKRKKYTEDLDIKIT 315
Query: 1438 SKRSQGPVHITAGSEPVPIGEDEDDDLDQET 1468
+ V +T +P PI + + D ET
Sbjct: 316 DDEEEEEVDVTGPIKPEPILPEPVQEPDGET 346
Score = 32.0 bits (71), Expect = 5.7
Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Query: 1045 EIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTE------SKRQAQRS 1098
E++ + + E R + ++ R K +DSDS+ + S + S
Sbjct: 1750 EVVARSRPTPQDYEMRVSPSDTTPLVSRSVPPVKLEDEDDSDSELDLSKLSPSSSSSSSS 1809
Query: 1099 SASESETEDSDDDKKPKRRGRPRS 1122
S+S S T++S+D+K+ K + RS
Sbjct: 1810 SSSSSSTDESEDEKEEKLTDQSRS 1833
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 523 bits (1348), Expect = e-148
Identities = 380/1158 (32%), Positives = 589/1158 (50%), Gaps = 161/1158 (13%)
Query: 12 DSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESESESA 71
D L +SH + + + + QS++ S H + + + Q S +S
Sbjct: 433 DHDLDRQFTSHLVTRPSDMAQTQLQSQARSWHSSFSNHQHLHDRNHLCLQRQPPSSKKSD 492
Query: 72 GSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSG 131
GS + L + + S+K++ V+ + S+QE + I E +
Sbjct: 493 GSGTYTKLQNTQVRVMSEKKQRKKVE---------------SESKQEKANRIISEAIAKA 537
Query: 132 SESGSPKRRGQRQLKKQEKWKQEPSED----EQEQGTSAESEPEQKKVKARRPVPRRTVP 187
E RG+R + + + P+ E+++G +S+P+ K K + +
Sbjct: 538 KE------RGERNIPRVMSPENFPTASVEGKEEKKGRRMKSKPKDKDSKKTKTCSKLK-E 590
Query: 188 KPRVKKQPKTQRGKRK-KQDSSDEDDDDDEAPKR-------QTRR--RAAKNVSYKEDDD 237
K ++ K T K+K K +SSDE D ++ P+ Q RR R K Y ED +
Sbjct: 591 KTKIGKLIITLGKKQKRKNESSDEISDAEQMPQHTLKDQDSQKRRSNRQIKRKKYAEDIE 650
Query: 238 FETDSDDL----------IEMTGEGV------DEQQDNSETIEKVLDSRLGKKGATGAST 281
+ +++ + GE + ++++ ++K+L SR KK +
Sbjct: 651 GKQSEEEVKGSMKIKKNSAPLPGEQPLQLFVENPSEEDAAIVDKILSSRTVKKEIS---- 706
Query: 282 TVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENF 341
P DTE ++ +K+K +SY+H W +EE L + K + +K++ F
Sbjct: 707 ----------PGVMIDTE------EFFVKYKNYSYLHCEWATEEQLLKDK-RIQQKIKRF 749
Query: 342 KKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAH 401
K ++ + + + E N Y V+RV+ V +
Sbjct: 750 KLRQAQRAHFFADMEEEP-------------FNPDYVEVDRVLEVSFCEDK--------- 787
Query: 402 SRKPAPSNEPE--YLCKWMGLPYSECSWE--DEALIGKKFQNCIDSFHSRNNSKTIPTRE 457
+ EP YL KW LPY + +WE ++ + K I+ F S+ +
Sbjct: 788 -----DTGEPVIYYLVKWCSLPYEDSTWELKEDVDLAK-----IEEFEQLQASRP----D 833
Query: 458 CKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTI 517
+ L + P + K + +LR+YQLEGLNWL +W + ILADEMGLGKTI
Sbjct: 834 TRRLDRPPSNIWKKIDQSRDYKNGNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTI 893
Query: 518 QTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREY 577
Q+I+FL Y + GPFLI+ PLST+ +W+REF W +INVVVY G L+SR I++Y
Sbjct: 894 QSITFL-YEILLTGIRGPFLIIAPLSTIANWEREFRTWT-DINVVVYHGSLISRQMIQQY 951
Query: 578 EWIHSQTK------RLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYK 631
E ++ +F A+ITT+E++L L +I W + +DEAHRLKN + L +
Sbjct: 952 EMYFRDSQGRIIRGAYRFQAIITTFEMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLE 1011
Query: 632 TLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGR-ENGYQSLH 690
L H++L+TGTPLQN+++EL+SLLHF+ P +F F ++ G + E Q L
Sbjct: 1012 GLKLMNLEHKVLLTGTPLQNTVEELFSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQ 1071
Query: 691 KVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTS- 749
+L+P +LRR+K+DVEK L K E I+ VE++ +QK+YY+ IL +N+ L+KG G T+
Sbjct: 1072 AILKPMMLRRLKEDVEKKLAPKEETIIEVELTNIQKKYYRAILEKNFSFLSKGA-GQTNV 1130
Query: 750 -GFLNIVMELKKCCNHCYLIKPPEENERENGQEI---------LLSLIRSSGKLILLDKL 799
+N +MEL+KCCNH YLIK EE ++ L ++I+S+GKL+L+DKL
Sbjct: 1131 PNLVNTMMELRKCCNHPYLIKGAEEKILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKL 1190
Query: 800 LTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSE 859
L +++ G++VLIFSQMVR LDIL +YL K Y ++R+DG ++G +R+ A+D F+ S+
Sbjct: 1191 LPKMKAGGHKVLIFSQMVRCLDILEDYLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSD 1250
Query: 860 DFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKG 919
F FLL TRAGGLGINL +ADT +IFDSDWNPQNDLQAQAR HRIGQ K V +YRLVT+
Sbjct: 1251 RFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRN 1310
Query: 920 TVEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDL 979
+ E E+ +RA K+ LD V+Q M +GR E+N G +K+E+ +L+ GA
Sbjct: 1311 SYEREMFDRASLKLGLDKAVLQSM--SGR---ESNVG--GIQQLSKKEIEDLLRRGAYGA 1363
Query: 980 FKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERP 1039
E E E S+ E DID+IL R + T ++ S F A+F + ++
Sbjct: 1364 IMEEEDEGSKFCEEDIDQIL----LRRTKTITIESEGRGSTFAKASFVASGNRTDISLDD 1419
Query: 1040 HKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSS 1099
W + ++ +++ E + PRIR T+ A +
Sbjct: 1420 PNFWQK---WAKKAEIDIEAISGRNSLVIDTPRIRKQTRPF-------------SATKDE 1463
Query: 1100 ASESETEDSDDDKKPKRR 1117
+E +S+ D+KPK R
Sbjct: 1464 LAELSEAESEGDEKPKLR 1481
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/100 (35%), Positives = 45/100 (45%), Gaps = 1/100 (1%)
Query: 8 SQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESE 67
S E SS S +SS S+S S S SGS S S S S S SSS SS S S E
Sbjct: 2136 SDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEE 2195
Query: 68 SESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVY 107
S+S ++Q A +E +A + +E D +
Sbjct: 2196 SDSDEEEAQK-RESTTHMKAYDEESVASLSTTQDETQDSF 2234
Score = 37.7 bits (86), Expect = 0.10
Identities = 31/107 (28%), Positives = 43/107 (40%), Gaps = 19/107 (17%)
Query: 15 LHSNASSHSASEEASGSDSGSQSESE-------------------QGSDPGSGHGSESNS 55
L N +S GS+S S S+S+ S GS S S+
Sbjct: 2112 LTPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSC 2171
Query: 56 SSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEE 102
SS SS S S + S S+ S S ++ E+ A K+E +K EE
Sbjct: 2172 SSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMKAYDEE 2218
Score = 36.2 bits (82), Expect = 0.30
Identities = 12/36 (33%), Positives = 22/36 (61%)
Query: 1261 WGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKI 1296
W + D LL+G+++HGY + I+ DP L +++
Sbjct: 1675 WDFDADKSLLIGVFKHGYEKYNTIRADPALCFLERV 1710
Score = 35.8 bits (81), Expect = 0.39
Identities = 56/239 (23%), Positives = 83/239 (34%), Gaps = 41/239 (17%)
Query: 1266 DSRLLLGIYEHGYGNWEL-IKTDPELKLTDKILPVETDKKPQGK---------QLQTRAD 1315
D LL+G +HG + I DPEL K + Q+ A
Sbjct: 1967 DRDLLIGAAKHGVSRTDYHILRDPELSFMAAQRNYSQSKMAHSRTSTPLLQQYQVALSAS 2026
Query: 1316 YLLKLLRKGLEKKGAVTGGEEAKLK----KRKPRVKKENKVPRLKEEHGI--ELSSPRHS 1369
L L R L+ KG + EE K+K K +P+ +E + ++ I E SP++
Sbjct: 2027 PLTSLPRL-LDAKGIIL--EEMKVKSENLKEEPQSSEEESMSSVETRTLIKSEPVSPKNG 2083
Query: 1370 DNPSEEGEVKDDG----------LEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKK 1419
P G+ K G P+ K+ + +K SS D + D ER
Sbjct: 2084 VLPQATGDQKSGGKCETDRRMVAARTEPLTPNPASKKPRVHKRGSESS-SDSDSDSERSS 2142
Query: 1420 SKDKKEKPKSGDA-----------KSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQE 1467
+ S + SSS S S T+ S E+ D D+E
Sbjct: 2143 CSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEE 2201
Score = 33.5 bits (75), Expect = 1.9
Identities = 32/133 (24%), Positives = 53/133 (39%), Gaps = 30/133 (22%)
Query: 1365 SPRHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEK------QMSSRKDKEGD---- 1414
S + SD ++++ + KK++KK E++ +EK + ++ + G+
Sbjct: 487 SSKKSDGSGTYTKLQNTQVRVMSEKKQRKKVESESKQEKANRIISEAIAKAKERGERNIP 546
Query: 1415 ---------------KERKKSKDKKEKPKSGDAK-----SSSKSKRSQGPVHITAGSEPV 1454
KE KK + K KPK D+K S K K G + IT G +
Sbjct: 547 RVMSPENFPTASVEGKEEKKGRRMKSKPKDKDSKKTKTCSKLKEKTKIGKLIITLGKKQK 606
Query: 1455 PIGEDEDDDLDQE 1467
E D+ D E
Sbjct: 607 RKNESSDEISDAE 619
>gi|164419749 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a1 isoform b [Homo sapiens]
Length = 1042
Score = 462 bits (1188), Expect = e-129
Identities = 310/892 (34%), Positives = 479/892 (53%), Gaps = 87/892 (9%)
Query: 342 KKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAH 401
KKKE + + K++ + + E++ +Y+ + K + L QT+ AH
Sbjct: 55 KKKEKNVSSFQLKLAAK-------APKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAH 107
Query: 402 SRKPAPSNEPEY-LCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKA 460
+P+ P L +G P + E ++LI D H R + ++
Sbjct: 108 FIQPSAQKSPTSPLNMKLGRPRIKKD-EKQSLISAG-----DYRHRRTEQEEDEELLSES 161
Query: 461 LKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTI 520
K + + P+Y+ G LRDYQ+ GLNWL + + ILADEMGLGKT+QTI
Sbjct: 162 RKTSNVCIRFEVSPSYVKGG--PLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTI 219
Query: 521 SFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWI 580
+ L YL H + GP +++VP STL +W EF+ W P + V+ ++GD +R +I
Sbjct: 220 ALLGYLKHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAA-----FI 274
Query: 581 HSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNH 640
+ +++ +T+YE+++K+K+V +W +L +DEAHR+KN+ S L + + +FKS +
Sbjct: 275 RDEMMPGEWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTN 334
Query: 641 RLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEE----DHGKGRENGYQSLHKVLEPF 696
RLL+TGTPLQN+L ELW+LL+F++P+ F +DF+ + G + + LH VL+PF
Sbjct: 335 RLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPF 394
Query: 697 LLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVM 756
LLRR+K DVEKSLP K E + + +S +Q+++Y IL ++ L + LNI+M
Sbjct: 395 LLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSGKMDKMRLLNILM 454
Query: 757 ELKKCCNHCYLIKPPEENERENGQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQM 816
+L+KCCNH YL E E ++S +SGK+++LDKLL +L+E+G+RVLIFSQM
Sbjct: 455 QLRKCCNHPYLFDGAEPGPPYTTDEHIVS---NSGKMVVLDKLLAKLKEQGSRVLIFSQM 511
Query: 817 VRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINL 876
R+LDIL +Y + Y + RLDG E R++A++ FNA S F F+LSTRAGGLGINL
Sbjct: 512 TRLLDILEDYCMWRGYEYCRLDGQTPHEEREEAIEAFNAPNSSKFIFMLSTRAGGLGINL 571
Query: 877 ASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLD 936
ASAD V+++DSDWNPQ DLQA RAHRIGQKK V ++RL+T TVEE I+ERA+ K+ LD
Sbjct: 572 ASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLD 631
Query: 937 HLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFKELEGEESEPQEMDID 996
+VIQ+ GR I SN KEE+ +++ GA +F +ESE + DI
Sbjct: 632 SIVIQQ----GRLI------DQQSNKLAKEEMLQMIRHGATHVF---ASKESELTDEDIT 678
Query: 997 EILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQRKKVE 1056
IL E + E++ + + + + NF M+ E+ L + +D+ E + +E
Sbjct: 679 TILERGEKKTAEMNERL--QKMGESSLRNF-RMDIEQSLYKFEGEDYREKQKLGMVEWIE 735
Query: 1057 EEERQKELE---EIYMLPRIRSSTKK--------AQTNDSDSDTESKR------------ 1093
+R+++ + Y +R S K Q N D R
Sbjct: 736 PPKRERKANYAVDAYFREALRVSEPKIPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYY 795
Query: 1094 ------------QAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTD---AEIRR 1138
+ ++ E + D +P K L +GFT+ + +
Sbjct: 796 RKTIGYKVPRNPDIPNPALAQREEQKKIDGAEPLTPEETEEKEKLLTQGFTNWTKRDFNQ 855
Query: 1139 FIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEE 1190
FIKA +K+G + ++ IAR+ E KS ++ + C + +Q+ E+
Sbjct: 856 FIKANEKYG--RDDIDNIAREVE--GKSPEEVMEYSAVFWERC-NELQDIEK 902
>gi|21071044 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a1 isoform a [Homo sapiens]
Length = 1054
Score = 453 bits (1166), Expect = e-127
Identities = 310/904 (34%), Positives = 479/904 (52%), Gaps = 99/904 (10%)
Query: 342 KKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAH 401
KKKE + + K++ + + E++ +Y+ + K + L QT+ AH
Sbjct: 55 KKKEKNVSSFQLKLAAK-------APKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAH 107
Query: 402 SRKPAPSNEPEY-LCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKA 460
+P+ P L +G P + E ++LI D H R + ++
Sbjct: 108 FIQPSAQKSPTSPLNMKLGRPRIKKD-EKQSLISAG-----DYRHRRTEQEEDEELLSES 161
Query: 461 LKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTI 520
K + + P+Y+ G LRDYQ+ GLNWL + + ILADEMGLGKT+QTI
Sbjct: 162 RKTSNVCIRFEVSPSYVKGG--PLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTI 219
Query: 521 SFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWI 580
+ L YL H + GP +++VP STL +W EF+ W P + V+ ++GD +R +I
Sbjct: 220 ALLGYLKHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAA-----FI 274
Query: 581 HSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNH 640
+ +++ +T+YE+++K+K+V +W +L +DEAHR+KN+ S L + + +FKS +
Sbjct: 275 RDEMMPGEWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTN 334
Query: 641 RLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEE----DHGKGRENGYQSLHKVLEPF 696
RLL+TGTPLQN+L ELW+LL+F++P+ F +DF+ + G + + LH VL+PF
Sbjct: 335 RLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPF 394
Query: 697 LLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVM 756
LLRR+K DVEKSLP K E + + +S +Q+++Y IL ++ L + LNI+M
Sbjct: 395 LLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSGKMDKMRLLNILM 454
Query: 757 ELKKCCNHCYLIKPPEENERENGQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQM 816
+L+KCCNH YL E E ++S +SGK+++LDKLL +L+E+G+RVLIFSQM
Sbjct: 455 QLRKCCNHPYLFDGAEPGPPYTTDEHIVS---NSGKMVVLDKLLAKLKEQGSRVLIFSQM 511
Query: 817 VRMLDILAEYLTIKHYPFQRLDGSIKGEIR------------KQALDHFNADGSEDFCFL 864
R+LDIL +Y + Y + RLDG E R ++A++ FNA S F F+
Sbjct: 512 TRLLDILEDYCMWRGYEYCRLDGQTPHEEREDKFLEVEFLGQREAIEAFNAPNSSKFIFM 571
Query: 865 LSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEE 924
LSTRAGGLGINLASAD V+++DSDWNPQ DLQA RAHRIGQKK V ++RL+T TVEE
Sbjct: 572 LSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEER 631
Query: 925 IIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFKELE 984
I+ERA+ K+ LD +VIQ+ GR I SN KEE+ +++ GA +F
Sbjct: 632 IVERAEIKLRLDSIVIQQ----GRLI------DQQSNKLAKEEMLQMIRHGATHVF---A 678
Query: 985 GEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWD 1044
+ESE + DI IL E + E++ + + + + NF M+ E+ L + +D+
Sbjct: 679 SKESELTDEDITTILERGEKKTAEMNERL--QKMGESSLRNF-RMDIEQSLYKFEGEDYR 735
Query: 1045 EIIPEEQRKKVEEEERQKELE---EIYMLPRIRSSTKK--------AQTNDSDSDTESKR 1093
E + +E +R+++ + Y +R S K Q N D R
Sbjct: 736 EKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRPPKQPNVQDFQFFPPR 795
Query: 1094 ------------------------QAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVE 1129
+ ++ E + D +P K L +
Sbjct: 796 LFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEPLTPEETEEKEKLLTQ 855
Query: 1130 GFTD---AEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQ 1186
GFT+ + +FIKA +K+G + ++ IAR+ E KS ++ + C + +Q
Sbjct: 856 GFTNWTKRDFNQFIKANEKYG--RDDIDNIAREVE--GKSPEEVMEYSAVFWERC-NELQ 910
Query: 1187 EYEE 1190
+ E+
Sbjct: 911 DIEK 914
>gi|21071058 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a5 [Homo sapiens]
Length = 1052
Score = 449 bits (1154), Expect = e-125
Identities = 340/1022 (33%), Positives = 525/1022 (51%), Gaps = 145/1022 (14%)
Query: 393 LGQTDFPAHSRKPAPSNEPEYLCKWM-GLPYSECSWEDEALIGKKFQNCI---DSFHSRN 448
L QT+ AH +PA P K G P + +DE QN + D H R
Sbjct: 96 LKQTELFAHFIQPAAQKTPTSPLKMKPGRPRIK---KDEK------QNLLSVGDYRHRRT 146
Query: 449 NSKT---IPTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSV 505
+ + T KA RF + P+Y+ +LRDYQ+ GLNWL + +
Sbjct: 147 EQEEDEELLTESSKATNVCTRF---EDSPSYVKWG--KLRDYQVRGLNWLISLYENGING 201
Query: 506 ILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYI 565
ILADEMGLGKT+QTIS L Y+ H + GP +++VP STL +W EF+ W P + V I
Sbjct: 202 ILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLI 261
Query: 566 GDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLKND 625
GD R ++ +++ +T+YE+L+K+K+V NW +L +DEAHR+KN+
Sbjct: 262 GDKEQRAA-----FVRDVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNE 316
Query: 626 DSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFEFWEDFEE----DHGKG 681
S L + + +FK+ +RLL+TGTPLQN+L ELWSLL+F++P+ F +DF+ ++ G
Sbjct: 317 KSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLG 376
Query: 682 RENGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALA 741
+ + LH VL PFLLRR+K DVEKSLP K E + V +S +Q+++Y IL ++ L
Sbjct: 377 DQKLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILN 436
Query: 742 KGTRGSTSGFLNIVMELKKCCNHCYLIKPPEENERENGQEILLSLIRSSGKLILLDKLLT 801
+ LNI+M+L+KCCNH YL E + L+ +SGK+++LDKLL
Sbjct: 437 SAGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTD---MHLVTNSGKMVVLDKLLP 493
Query: 802 RLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDF 861
+L+E+G+RVLIFSQM R+LDIL +Y ++Y + RLDG + R+ +++ +N S F
Sbjct: 494 KLKEQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKF 553
Query: 862 CFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTV 921
F+LSTRAGGLGINLA+AD V+++DSDWNPQ DLQA RAHRIGQ K V ++R +T TV
Sbjct: 554 VFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTV 613
Query: 922 EEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFK 981
EE I+ERA+ K+ LD +VIQ+ GR + N N K+E+ +++ GA +F
Sbjct: 614 EERIVERAEMKLRLDSIVIQQ----GRLV------DQNLNKIGKDEMLQMIRHGATHVF- 662
Query: 982 ELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEEL---EER 1038
+ESE + DID IL + E++ + + + + NF TM+ E + E
Sbjct: 663 --ASKESEITDEDIDGILERGAKKTAEMNEKLSK--MGESSLRNF-TMDTESSVYNFEGE 717
Query: 1039 PHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKA--------QTNDSD---- 1086
+++ +I E + + E + + Y +R S KA Q N D
Sbjct: 718 DYREKQKIAFTEWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPKQPNVQDFQFF 777
Query: 1087 --------------------------SDTESKRQAQRSSASESETEDSDDDKKPKRRGRP 1120
+ + QAQ+ + + +S +D++ + +
Sbjct: 778 PPRLFELLEKEILFYRKTIGYKVPRNPELPNAAQAQKEEQLKIDEAESLNDEELEEK--- 834
Query: 1121 RSVRKDLVEGFTD---AEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELI 1177
K L +GFT+ + +FIKA +K+G + +E IAR+ E K+ ++ +
Sbjct: 835 ---EKLLTQGFTNWNKRDFNQFIKANEKWG--RDDIENIAREVE--GKTPEEVIEYSAVF 887
Query: 1178 HNSCVSAMQEYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIP 1237
C + +Q+ E++ G+ +RR IS + I +++ F L S
Sbjct: 888 WERC-NELQDI-EKIMAQIERGEARIQRR-----ISIKKALDTKIGRYKAPFHQLRISYG 940
Query: 1238 VD-----PEEKKKYCLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKL 1292
+ EE+ ++ L C + FD E V D+ R + I+ P+ +
Sbjct: 941 TNKGKNYTEEEDRF-LICMLHKLGFDKE-NVYDELR-------------QCIRNSPQFRF 985
Query: 1293 TDKILPVETDKKPQGKQLQTRADYLLKLLRK---GLEKKGAVTGGEEAKLKKRKPRVKKE 1349
D L K +LQ R + L+ L+ + LE+K E+A+ KKR P+ +
Sbjct: 986 -DWFL-----KSRTAMELQRRCNTLITLIERENMELEEK------EKAEKKKRGPKPSTQ 1033
Query: 1350 NK 1351
+
Sbjct: 1034 KR 1035
>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform F [Homo sapiens]
Length = 1613
Score = 422 bits (1086), Expect = e-117
Identities = 295/815 (36%), Positives = 430/815 (52%), Gaps = 99/815 (12%)
Query: 484 LRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLS 543
L+ YQ++GL WL + N + ILADEMGLGKTIQTI+ ++YL ++ GPFLI+VPLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 544 TLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDK 603
TL++W EF+ WAP + V Y G +R Q + KFN L+TTYE ++KDK
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVP------QLRSGKFNVLLTTYEYIIKDK 867
Query: 604 TVLGSINWAFLGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 662
+L I W ++ VDE HR+KN L + L + + RLL+TGTPLQN L ELW+LL+F
Sbjct: 868 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNF 927
Query: 663 IMPEKFEFWEDFE-----------EDHGKGRENGY---QSLHKVLEPFLLRRVKKDVEKS 708
++P F+ FE E E + LHKVL PFLLRR+KK+VE
Sbjct: 928 LLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQ 987
Query: 709 LPAKVEQILRVEMSALQKQYY-----KWILTRNYKALAKGTRGSTSGFLNIVMELKKCCN 763
LP KVE +++ +MSALQ+ Y K +L + K +G T +N +M+L+K CN
Sbjct: 988 LPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICN 1047
Query: 764 HCYLIKPPEENEREN-----GQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVR 818
H Y+ + EE+ E+ G L L R+SGK LLD++L +LR ++VL+F QM
Sbjct: 1048 HPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTS 1107
Query: 819 MLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLAS 878
++ I+ +Y + + + RLDG+ K E R L FN GSE F FLLSTRAGGLG+NL S
Sbjct: 1108 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQS 1167
Query: 879 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHL 938
ADTV+IFDSDWNP DLQAQ RAHRIGQ+ +V + RL T +VEE+I+ AK K+ +D
Sbjct: 1168 ADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1227
Query: 939 VIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFK-ELEGEESEPQ------ 991
VIQ + + S F L AIL+ +D + E+ +E+ Q
Sbjct: 1228 VIQ------AGMFDQKSSSHERRAF----LQAILEHEEQDEEEDEVPDDETVNQMIARHE 1277
Query: 992 -------EMDIDEILRLAETRENEVSTSATDELLS-----QFKVANFATMEDEEEL---- 1035
MD+D A + + DEL S +V E+EE++
Sbjct: 1278 EEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRG 1337
Query: 1036 -EERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQ 1094
R D+ + + E+Q K EE +E+EE + + +SS K+ + +D+ S T
Sbjct: 1338 SRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEE--EVRQKKSSRKRKRDSDAGSST----- 1390
Query: 1095 AQRSSASESETEDSDDDKKPKRRGRP-------------RSVRK--DLVEGFTDAEIRRF 1139
+ S + D+ KK K+RGRP + ++K D V + D+ R+
Sbjct: 1391 ---PTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSGRQL 1447
Query: 1140 IKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQ---LKENA 1196
+ + + L + + EL+ K V D K++ E I N ++ + E+ L +NA
Sbjct: 1448 SEVF----IQLPSRKELPEYYELIRKPV-DFKKIKERIRNHKYRSLNDLEKDVMLLCQNA 1502
Query: 1197 SEGKGPGKR-RGPTIKISGVQVNVKSIIQHEEEFE 1230
G +I + V +V+ I+ E++ E
Sbjct: 1503 QTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSE 1537
Score = 40.0 bits (92), Expect = 0.021
Identities = 53/239 (22%), Positives = 104/239 (43%), Gaps = 24/239 (10%)
Query: 2 MRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE 61
+R K S++ + +S+ + S + D S+ + ++G P + ++ +
Sbjct: 1371 VRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMK 1430
Query: 62 SQSESE---SESAGSKSQPV---LPEAKEKPASKK--ERIADVKKMWEEYPDVYGVRRSN 113
++ +S+G + V LP KE P + + D KK+ E + + R N
Sbjct: 1431 KIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRN-HKYRSLN 1489
Query: 114 RSR-------QEPSRFNIKE----EASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQ 162
Q FN++ E S +S R ++++K++ + E SE+E+E
Sbjct: 1490 DLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVR--QKIEKEDDSEGEESEEEEE- 1546
Query: 163 GTSAESEPEQKKVKARRPVPRRTVPKPRVK-KQPKTQRGKRKKQDSSDEDDDDDEAPKR 220
G SE E + VK + + R+ + R+K + + RG R K SD+D ++++ R
Sbjct: 1547 GEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDR 1605
Score = 36.6 bits (83), Expect = 0.23
Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 26/137 (18%)
Query: 1335 EEAKLKKRKPRVKKENKVP-----------RL---KEEHGIELSSPRH------SDNPSE 1374
EEA+ KRKPR+ +E+++P RL +EE + RH SD+ +E
Sbjct: 1293 EEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTE 1352
Query: 1375 E---GEVKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGD 1431
+ +++ LE+ + +QKK K ++ S + R K + K++ K G
Sbjct: 1353 KQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGR 1412
Query: 1432 AKSSSKSKRSQGPVHIT 1448
+ K S P ++T
Sbjct: 1413 PPA---EKLSPNPPNLT 1426
Score = 34.3 bits (77), Expect = 1.1
Identities = 49/240 (20%), Positives = 97/240 (40%), Gaps = 32/240 (13%)
Query: 1216 QVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDS-------- 1267
Q + SI+QH ++F+ H+S+ K LT V H + E + ++
Sbjct: 473 QEYLNSILQHAKDFKEYHRSV-----TGKIQKLTKAVATYHANTEREQKKENERIEKERM 527
Query: 1268 RLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEK 1327
R L+ E GY K++ + DK+ LQ +Y+ L +
Sbjct: 528 RRLMAEDEEGY---------------RKLIDQKKDKR-LAYLLQQTDEYVANLTELVRQH 571
Query: 1328 KGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSP 1387
K A E+ K KK+K E + P + + + + SD P + V+ +
Sbjct: 572 KAAQVAKEKKKKKKKKKAENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGT 631
Query: 1388 MKKKQKKKEN--KENKEKQMSSRKD-KEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGP 1444
K + E + N +++ R D +E E ++ ++++E+P++ + ++ + P
Sbjct: 632 DAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIP 691
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/91 (21%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 1378 VKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPK-SGDAKSSS 1436
+ +D + + ++K KE+ + S +++EG++E +S+ + K K K +
Sbjct: 1512 IYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKA 1571
Query: 1437 KSKRSQGPVHITAGSEPVPIGEDEDDDLDQE 1467
+ + G + GS P+ D+D + +QE
Sbjct: 1572 QDRLKGGRRRPSRGSRAKPVVSDDDSEEEQE 1602
>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform E [Homo sapiens]
Length = 1614
Score = 422 bits (1084), Expect = e-117
Identities = 292/812 (35%), Positives = 427/812 (52%), Gaps = 92/812 (11%)
Query: 484 LRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLS 543
L+ YQ++GL WL + N + ILADEMGLGKTIQTI+ ++YL ++ GPFLI+VPLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 544 TLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDK 603
TL++W EF+ WAP + V Y G +R Q + KFN L+TTYE ++KDK
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVP------QLRSGKFNVLLTTYEYIIKDK 867
Query: 604 TVLGSINWAFLGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 662
+L I W ++ VDE HR+KN L + L + + RLL+TGTPLQN L ELW+LL+F
Sbjct: 868 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNF 927
Query: 663 IMPEKFEFWEDFE-----------EDHGKGRENGY---QSLHKVLEPFLLRRVKKDVEKS 708
++P F+ FE E E + LHKVL PFLLRR+KK+VE
Sbjct: 928 LLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQ 987
Query: 709 LPAKVEQILRVEMSALQKQYY-----KWILTRNYKALAKGTRGSTSGFLNIVMELKKCCN 763
LP KVE +++ +MSALQ+ Y K +L + K +G T +N +M+L+K CN
Sbjct: 988 LPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICN 1047
Query: 764 HCYLIKPPEENEREN-----GQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVR 818
H Y+ + EE+ E+ G L L R+SGK LLD++L +LR ++VL+F QM
Sbjct: 1048 HPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTS 1107
Query: 819 MLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLAS 878
++ I+ +Y + + + RLDG+ K E R L FN GSE F FLLSTRAGGLG+NL S
Sbjct: 1108 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQS 1167
Query: 879 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHL 938
ADTV+IFDSDWNP DLQAQ RAHRIGQ+ +V + RL T +VEE+I+ AK K+ +D
Sbjct: 1168 ADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1227
Query: 939 VIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFK-ELEGEESEPQ------ 991
VIQ + + S F L AIL+ +D + E+ +E+ Q
Sbjct: 1228 VIQ------AGMFDQKSSSHERRAF----LQAILEHEEQDEEEDEVPDDETVNQMIARHE 1277
Query: 992 -------EMDIDEILRLAETRENEVSTSATDELLS-----QFKVANFATMEDEEEL---- 1035
MD+D A + + DEL S +V E+EE++
Sbjct: 1278 EEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRG 1337
Query: 1036 -EERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQ 1094
R D+ + + E+Q K EE +E+EE + + +SS K+ + +D+ S T
Sbjct: 1338 SRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEE--EVRQKKSSRKRKRDSDAGSST----- 1390
Query: 1095 AQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFG------- 1147
+ S + D+ KK K+RGRP + + ++++ + A K+
Sbjct: 1391 ---PTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQ 1447
Query: 1148 -----LPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQ---LKENASEG 1199
+ L + + EL+ K V D K++ E I N ++ + E+ L +NA
Sbjct: 1448 LSEVFIQLPSRKELPEYYELIRKPV-DFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTF 1506
Query: 1200 KGPGKR-RGPTIKISGVQVNVKSIIQHEEEFE 1230
G +I + V +V+ I+ E++ E
Sbjct: 1507 NLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSE 1538
Score = 40.0 bits (92), Expect = 0.021
Identities = 53/240 (22%), Positives = 104/240 (43%), Gaps = 25/240 (10%)
Query: 2 MRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE 61
+R K S++ + +S+ + S + D S+ + ++G P + ++ +
Sbjct: 1371 VRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMK 1430
Query: 62 SQSES----ESESAGSKSQPV---LPEAKEKPASKK--ERIADVKKMWEEYPDVYGVRRS 112
++ + S+G + V LP KE P + + D KK+ E + + R
Sbjct: 1431 KIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRN-HKYRSL 1489
Query: 113 NRSR-------QEPSRFNIKE----EASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQE 161
N Q FN++ E S +S R ++++K++ + E SE+E+E
Sbjct: 1490 NDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVR--QKIEKEDDSEGEESEEEEE 1547
Query: 162 QGTSAESEPEQKKVKARRPVPRRTVPKPRVK-KQPKTQRGKRKKQDSSDEDDDDDEAPKR 220
G SE E + VK + + R+ + R+K + + RG R K SD+D ++++ R
Sbjct: 1548 -GEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDR 1606
Score = 36.6 bits (83), Expect = 0.23
Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 26/137 (18%)
Query: 1335 EEAKLKKRKPRVKKENKVP-----------RL---KEEHGIELSSPRH------SDNPSE 1374
EEA+ KRKPR+ +E+++P RL +EE + RH SD+ +E
Sbjct: 1293 EEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTE 1352
Query: 1375 E---GEVKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGD 1431
+ +++ LE+ + +QKK K ++ S + R K + K++ K G
Sbjct: 1353 KQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGR 1412
Query: 1432 AKSSSKSKRSQGPVHIT 1448
+ K S P ++T
Sbjct: 1413 PPA---EKLSPNPPNLT 1426
Score = 34.3 bits (77), Expect = 1.1
Identities = 49/240 (20%), Positives = 97/240 (40%), Gaps = 32/240 (13%)
Query: 1216 QVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDS-------- 1267
Q + SI+QH ++F+ H+S+ K LT V H + E + ++
Sbjct: 473 QEYLNSILQHAKDFKEYHRSV-----TGKIQKLTKAVATYHANTEREQKKENERIEKERM 527
Query: 1268 RLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEK 1327
R L+ E GY K++ + DK+ LQ +Y+ L +
Sbjct: 528 RRLMAEDEEGY---------------RKLIDQKKDKR-LAYLLQQTDEYVANLTELVRQH 571
Query: 1328 KGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSP 1387
K A E+ K KK+K E + P + + + + SD P + V+ +
Sbjct: 572 KAAQVAKEKKKKKKKKKAENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGT 631
Query: 1388 MKKKQKKKEN--KENKEKQMSSRKD-KEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGP 1444
K + E + N +++ R D +E E ++ ++++E+P++ + ++ + P
Sbjct: 632 DAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIP 691
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/91 (21%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 1378 VKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPK-SGDAKSSS 1436
+ +D + + ++K KE+ + S +++EG++E +S+ + K K K +
Sbjct: 1513 IYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKA 1572
Query: 1437 KSKRSQGPVHITAGSEPVPIGEDEDDDLDQE 1467
+ + G + GS P+ D+D + +QE
Sbjct: 1573 QDRLKGGRRRPSRGSRAKPVVSDDDSEEEQE 1603
>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform D [Homo sapiens]
Length = 1616
Score = 421 bits (1083), Expect = e-117
Identities = 295/815 (36%), Positives = 430/815 (52%), Gaps = 96/815 (11%)
Query: 484 LRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLS 543
L+ YQ++GL WL + N + ILADEMGLGKTIQTI+ ++YL ++ GPFLI+VPLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 544 TLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDK 603
TL++W EF+ WAP + V Y G +R Q + KFN L+TTYE ++KDK
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVP------QLRSGKFNVLLTTYEYIIKDK 867
Query: 604 TVLGSINWAFLGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 662
+L I W ++ VDE HR+KN L + L + + RLL+TGTPLQN L ELW+LL+F
Sbjct: 868 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNF 927
Query: 663 IMPEKFEFWEDFE-----------EDHGKGRENGY---QSLHKVLEPFLLRRVKKDVEKS 708
++P F+ FE E E + LHKVL PFLLRR+KK+VE
Sbjct: 928 LLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQ 987
Query: 709 LPAKVEQILRVEMSALQKQYY-----KWILTRNYKALAKGTRGSTSGFLNIVMELKKCCN 763
LP KVE +++ +MSALQ+ Y K +L + K +G T +N +M+L+K CN
Sbjct: 988 LPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICN 1047
Query: 764 HCYLIKPPEENEREN-----GQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVR 818
H Y+ + EE+ E+ G L L R+SGK LLD++L +LR ++VL+F QM
Sbjct: 1048 HPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTS 1107
Query: 819 MLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLAS 878
++ I+ +Y + + + RLDG+ K E R L FN GSE F FLLSTRAGGLG+NL S
Sbjct: 1108 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQS 1167
Query: 879 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHL 938
ADTV+IFDSDWNP DLQAQ RAHRIGQ+ +V + RL T +VEE+I+ AK K+ +D
Sbjct: 1168 ADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1227
Query: 939 VIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFK-ELEGEESEPQ------ 991
VIQ + + S F L AIL+ +D + E+ +E+ Q
Sbjct: 1228 VIQ------AGMFDQKSSSHERRAF----LQAILEHEEQDEEEDEVPDDETVNQMIARHE 1277
Query: 992 -------EMDIDEILRLAETRENEVSTSATDELLS-----QFKVANFATMEDEEEL---- 1035
MD+D A + + DEL S +V E+EE++
Sbjct: 1278 EEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRG 1337
Query: 1036 -EERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQ 1094
R D+ + + E+Q K + + LEEI R + S++K + DSD+ + +
Sbjct: 1338 SRHRKEVDYSDSLTEKQWLKTLKAIEEGTLEEIEEEVRQKKSSRK-RKRDSDAGSSTPTT 1396
Query: 1095 AQRSSASESETEDSDDDKKPKRRGRP-------------RSVRK--DLVEGFTDAEIRRF 1139
+ RS + D+ KK K+RGRP + ++K D V + D+ R+
Sbjct: 1397 STRS------RDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSGRQL 1450
Query: 1140 IKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQ---LKENA 1196
+ + + L + + EL+ K V D K++ E I N ++ + E+ L +NA
Sbjct: 1451 SEVF----IQLPSRKELPEYYELIRKPV-DFKKIKERIRNHKYRSLNDLEKDVMLLCQNA 1505
Query: 1197 SEGKGPGKR-RGPTIKISGVQVNVKSIIQHEEEFE 1230
G +I + V +V+ I+ E++ E
Sbjct: 1506 QTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSE 1540
Score = 40.0 bits (92), Expect = 0.021
Identities = 53/239 (22%), Positives = 104/239 (43%), Gaps = 24/239 (10%)
Query: 2 MRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE 61
+R K S++ + +S+ + S + D S+ + ++G P + ++ +
Sbjct: 1374 VRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMK 1433
Query: 62 SQSESE---SESAGSKSQPV---LPEAKEKPASKK--ERIADVKKMWEEYPDVYGVRRSN 113
++ +S+G + V LP KE P + + D KK+ E + + R N
Sbjct: 1434 KIVDAVIKYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRN-HKYRSLN 1492
Query: 114 RSR-------QEPSRFNIKE----EASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQ 162
Q FN++ E S +S R ++++K++ + E SE+E+E
Sbjct: 1493 DLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVR--QKIEKEDDSEGEESEEEEE- 1549
Query: 163 GTSAESEPEQKKVKARRPVPRRTVPKPRVK-KQPKTQRGKRKKQDSSDEDDDDDEAPKR 220
G SE E + VK + + R+ + R+K + + RG R K SD+D ++++ R
Sbjct: 1550 GEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDR 1608
Score = 35.4 bits (80), Expect = 0.51
Identities = 35/140 (25%), Positives = 61/140 (43%), Gaps = 29/140 (20%)
Query: 1335 EEAKLKKRKPRVKKENKVP-----------RL---KEEHGIELSSPRH------SDNPSE 1374
EEA+ KRKPR+ +E+++P RL +EE + RH SD+ +E
Sbjct: 1293 EEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTE 1352
Query: 1375 E------GEVKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPK 1428
+ +++ LE+ + +QKK K ++ S + R K + K++ K
Sbjct: 1353 KQWLKTLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKK 1412
Query: 1429 SGDAKSSSKSKRSQGPVHIT 1448
G + K S P ++T
Sbjct: 1413 RGRPPA---EKLSPNPPNLT 1429
Score = 34.3 bits (77), Expect = 1.1
Identities = 49/240 (20%), Positives = 97/240 (40%), Gaps = 32/240 (13%)
Query: 1216 QVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDS-------- 1267
Q + SI+QH ++F+ H+S+ K LT V H + E + ++
Sbjct: 473 QEYLNSILQHAKDFKEYHRSV-----TGKIQKLTKAVATYHANTEREQKKENERIEKERM 527
Query: 1268 RLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEK 1327
R L+ E GY K++ + DK+ LQ +Y+ L +
Sbjct: 528 RRLMAEDEEGY---------------RKLIDQKKDKR-LAYLLQQTDEYVANLTELVRQH 571
Query: 1328 KGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSP 1387
K A E+ K KK+K E + P + + + + SD P + V+ +
Sbjct: 572 KAAQVAKEKKKKKKKKKAENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGT 631
Query: 1388 MKKKQKKKEN--KENKEKQMSSRKD-KEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGP 1444
K + E + N +++ R D +E E ++ ++++E+P++ + ++ + P
Sbjct: 632 DAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIP 691
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/91 (21%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 1378 VKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPK-SGDAKSSS 1436
+ +D + + ++K KE+ + S +++EG++E +S+ + K K K +
Sbjct: 1515 IYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKA 1574
Query: 1437 KSKRSQGPVHITAGSEPVPIGEDEDDDLDQE 1467
+ + G + GS P+ D+D + +QE
Sbjct: 1575 QDRLKGGRRRPSRGSRAKPVVSDDDSEEEQE 1605
>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform C [Homo sapiens]
Length = 1617
Score = 421 bits (1081), Expect = e-117
Identities = 292/812 (35%), Positives = 427/812 (52%), Gaps = 89/812 (10%)
Query: 484 LRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLS 543
L+ YQ++GL WL + N + ILADEMGLGKTIQTI+ ++YL ++ GPFLI+VPLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 544 TLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDK 603
TL++W EF+ WAP + V Y G +R Q + KFN L+TTYE ++KDK
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVP------QLRSGKFNVLLTTYEYIIKDK 867
Query: 604 TVLGSINWAFLGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 662
+L I W ++ VDE HR+KN L + L + + RLL+TGTPLQN L ELW+LL+F
Sbjct: 868 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNF 927
Query: 663 IMPEKFEFWEDFE-----------EDHGKGRENGY---QSLHKVLEPFLLRRVKKDVEKS 708
++P F+ FE E E + LHKVL PFLLRR+KK+VE
Sbjct: 928 LLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQ 987
Query: 709 LPAKVEQILRVEMSALQKQYY-----KWILTRNYKALAKGTRGSTSGFLNIVMELKKCCN 763
LP KVE +++ +MSALQ+ Y K +L + K +G T +N +M+L+K CN
Sbjct: 988 LPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICN 1047
Query: 764 HCYLIKPPEENEREN-----GQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVR 818
H Y+ + EE+ E+ G L L R+SGK LLD++L +LR ++VL+F QM
Sbjct: 1048 HPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTS 1107
Query: 819 MLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLAS 878
++ I+ +Y + + + RLDG+ K E R L FN GSE F FLLSTRAGGLG+NL S
Sbjct: 1108 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQS 1167
Query: 879 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHL 938
ADTV+IFDSDWNP DLQAQ RAHRIGQ+ +V + RL T +VEE+I+ AK K+ +D
Sbjct: 1168 ADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1227
Query: 939 VIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFK-ELEGEESEPQ------ 991
VIQ + + S F L AIL+ +D + E+ +E+ Q
Sbjct: 1228 VIQ------AGMFDQKSSSHERRAF----LQAILEHEEQDEEEDEVPDDETVNQMIARHE 1277
Query: 992 -------EMDIDEILRLAETRENEVSTSATDELLS-----QFKVANFATMEDEEEL---- 1035
MD+D A + + DEL S +V E+EE++
Sbjct: 1278 EEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRG 1337
Query: 1036 -EERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQ 1094
R D+ + + E+Q K + + LEEI R + S++K + DSD+ + +
Sbjct: 1338 SRHRKEVDYSDSLTEKQWLKTLKAIEEGTLEEIEEEVRQKKSSRK-RKRDSDAGSSTPTT 1396
Query: 1095 AQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFG------- 1147
+ RS + D+ KK K+RGRP + + ++++ + A K+
Sbjct: 1397 STRS------RDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQ 1450
Query: 1148 -----LPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQ---LKENASEG 1199
+ L + + EL+ K V D K++ E I N ++ + E+ L +NA
Sbjct: 1451 LSEVFIQLPSRKELPEYYELIRKPV-DFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTF 1509
Query: 1200 KGPGKR-RGPTIKISGVQVNVKSIIQHEEEFE 1230
G +I + V +V+ I+ E++ E
Sbjct: 1510 NLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSE 1541
Score = 40.0 bits (92), Expect = 0.021
Identities = 53/240 (22%), Positives = 104/240 (43%), Gaps = 25/240 (10%)
Query: 2 MRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE 61
+R K S++ + +S+ + S + D S+ + ++G P + ++ +
Sbjct: 1374 VRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMK 1433
Query: 62 SQSES----ESESAGSKSQPV---LPEAKEKPASKK--ERIADVKKMWEEYPDVYGVRRS 112
++ + S+G + V LP KE P + + D KK+ E + + R
Sbjct: 1434 KIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRN-HKYRSL 1492
Query: 113 NRSR-------QEPSRFNIKE----EASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQE 161
N Q FN++ E S +S R ++++K++ + E SE+E+E
Sbjct: 1493 NDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVR--QKIEKEDDSEGEESEEEEE 1550
Query: 162 QGTSAESEPEQKKVKARRPVPRRTVPKPRVK-KQPKTQRGKRKKQDSSDEDDDDDEAPKR 220
G SE E + VK + + R+ + R+K + + RG R K SD+D ++++ R
Sbjct: 1551 -GEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDR 1609
Score = 35.4 bits (80), Expect = 0.51
Identities = 35/140 (25%), Positives = 61/140 (43%), Gaps = 29/140 (20%)
Query: 1335 EEAKLKKRKPRVKKENKVP-----------RL---KEEHGIELSSPRH------SDNPSE 1374
EEA+ KRKPR+ +E+++P RL +EE + RH SD+ +E
Sbjct: 1293 EEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTE 1352
Query: 1375 E------GEVKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPK 1428
+ +++ LE+ + +QKK K ++ S + R K + K++ K
Sbjct: 1353 KQWLKTLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKK 1412
Query: 1429 SGDAKSSSKSKRSQGPVHIT 1448
G + K S P ++T
Sbjct: 1413 RGRPPA---EKLSPNPPNLT 1429
Score = 34.3 bits (77), Expect = 1.1
Identities = 49/240 (20%), Positives = 97/240 (40%), Gaps = 32/240 (13%)
Query: 1216 QVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDS-------- 1267
Q + SI+QH ++F+ H+S+ K LT V H + E + ++
Sbjct: 473 QEYLNSILQHAKDFKEYHRSV-----TGKIQKLTKAVATYHANTEREQKKENERIEKERM 527
Query: 1268 RLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEK 1327
R L+ E GY K++ + DK+ LQ +Y+ L +
Sbjct: 528 RRLMAEDEEGY---------------RKLIDQKKDKR-LAYLLQQTDEYVANLTELVRQH 571
Query: 1328 KGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSP 1387
K A E+ K KK+K E + P + + + + SD P + V+ +
Sbjct: 572 KAAQVAKEKKKKKKKKKAENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGT 631
Query: 1388 MKKKQKKKEN--KENKEKQMSSRKD-KEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGP 1444
K + E + N +++ R D +E E ++ ++++E+P++ + ++ + P
Sbjct: 632 DAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIP 691
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/91 (21%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 1378 VKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPK-SGDAKSSS 1436
+ +D + + ++K KE+ + S +++EG++E +S+ + K K K +
Sbjct: 1516 IYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKA 1575
Query: 1437 KSKRSQGPVHITAGSEPVPIGEDEDDDLDQE 1467
+ + G + GS P+ D+D + +QE
Sbjct: 1576 QDRLKGGRRRPSRGSRAKPVVSDDDSEEEQE 1606
>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 412 bits (1059), Expect = e-114
Identities = 294/835 (35%), Positives = 426/835 (51%), Gaps = 105/835 (12%)
Query: 484 LRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLS 543
L+ YQ++GL WL + N + ILADEMGLGKTIQTI+ ++YL ++ GPFLI+VPLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 544 TLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDK 603
TL++W EF+ WAP + V Y G +R Q + KFN L+TTYE ++KDK
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVP------QLRSGKFNVLLTTYEYIIKDK 867
Query: 604 TVLGSINWAFLGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 662
+L I W ++ VDE HR+KN L + L + + RLL+TGTPLQN L ELW+LL+F
Sbjct: 868 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNF 927
Query: 663 IMPEKFEFWEDFE-----------EDHGKGRENGY---QSLHKVLEPFLLRRVKKDVEKS 708
++P F+ FE E E + LHKVL PFLLRR+KK+VE
Sbjct: 928 LLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQ 987
Query: 709 LPAKVEQILRVEMSALQKQYY-----KWILTRNYKALAKGTRGSTSGFLNIVMELKKCCN 763
LP KVE +++ +MSALQ+ Y K +L + K +G T +N +M+L+K CN
Sbjct: 988 LPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICN 1047
Query: 764 HCYLIKPPEENEREN-----GQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVR 818
H Y+ + EE+ E+ G L L R+SGK LLD++L +LR ++VL+F QM
Sbjct: 1048 HPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTS 1107
Query: 819 MLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLAS 878
++ I+ +Y + + + RLDG+ K E R L FN GSE F FLLSTRAGGLG+NL S
Sbjct: 1108 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQS 1167
Query: 879 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHL 938
ADTV+IFDSDWNP DLQAQ RAHRIGQ+ +V + RL T +VEE+I+ AK K+ +D
Sbjct: 1168 ADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1227
Query: 939 VIQ--RMDTTG---------RTILEN-----------NSGRSN---------------SN 961
VIQ D + ILE+ SG ++
Sbjct: 1228 VIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEE 1287
Query: 962 PFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLS-- 1019
P KEE + E E MD+D A + + DEL S
Sbjct: 1288 PPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWI 1347
Query: 1020 ---QFKVANFATMEDEEEL-----EERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLP 1071
+V E+EE++ R D+ + + E+Q K EE +E+EE +
Sbjct: 1348 IKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEE--EVR 1405
Query: 1072 RIRSSTKKAQTNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGF 1131
+ +SS K+ + +D+ S T + S + D+ KK K+RGRP + +
Sbjct: 1406 QKKSSRKRKRDSDAGSST--------PTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPN 1457
Query: 1132 TDAEIRRFIKAYKKFG------------LPLERLECIARDAELVDKSVADLKRLGELIHN 1179
++++ + A K+ + L + + EL+ K V D K++ E I N
Sbjct: 1458 LTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPV-DFKKIKERIRN 1516
Query: 1180 SCVSAMQEYEEQ---LKENASEGKGPGKR-RGPTIKISGVQVNVKSIIQHEEEFE 1230
++ + E+ L +NA G +I + V +V+ I+ E++ E
Sbjct: 1517 HKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSE 1571
Score = 40.0 bits (92), Expect = 0.021
Identities = 53/240 (22%), Positives = 104/240 (43%), Gaps = 25/240 (10%)
Query: 2 MRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE 61
+R K S++ + +S+ + S + D S+ + ++G P + ++ +
Sbjct: 1404 VRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMK 1463
Query: 62 SQSES----ESESAGSKSQPV---LPEAKEKPASKK--ERIADVKKMWEEYPDVYGVRRS 112
++ + S+G + V LP KE P + + D KK+ E + + R
Sbjct: 1464 KIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRN-HKYRSL 1522
Query: 113 NRSR-------QEPSRFNIKE----EASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQE 161
N Q FN++ E S +S R ++++K++ + E SE+E+E
Sbjct: 1523 NDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVR--QKIEKEDDSEGEESEEEEE 1580
Query: 162 QGTSAESEPEQKKVKARRPVPRRTVPKPRVK-KQPKTQRGKRKKQDSSDEDDDDDEAPKR 220
G SE E + VK + + R+ + R+K + + RG R K SD+D ++++ R
Sbjct: 1581 -GEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDR 1639
Score = 37.0 bits (84), Expect = 0.18
Identities = 42/185 (22%), Positives = 79/185 (42%), Gaps = 35/185 (18%)
Query: 1287 DPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKPRV 1346
+P LK D++ D + + + + +R L+++ EEA+ KRKPR+
Sbjct: 1287 EPPLKEEDEV----PDDETVNQMIARHEEEFDLFMRMDLDRRR-----EEARNPKRKPRL 1337
Query: 1347 KKENKVP-----------RL---KEEHGIELSSPRH------SDNPSEE---GEVKDDGL 1383
+E+++P RL +EE + RH SD+ +E+ +++ L
Sbjct: 1338 MEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTL 1397
Query: 1384 EKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQG 1443
E+ + +QKK K ++ S + R K + K++ K G + K S
Sbjct: 1398 EEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPA---EKLSPN 1454
Query: 1444 PVHIT 1448
P ++T
Sbjct: 1455 PPNLT 1459
Score = 34.3 bits (77), Expect = 1.1
Identities = 49/240 (20%), Positives = 97/240 (40%), Gaps = 32/240 (13%)
Query: 1216 QVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDS-------- 1267
Q + SI+QH ++F+ H+S+ K LT V H + E + ++
Sbjct: 473 QEYLNSILQHAKDFKEYHRSV-----TGKIQKLTKAVATYHANTEREQKKENERIEKERM 527
Query: 1268 RLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEK 1327
R L+ E GY K++ + DK+ LQ +Y+ L +
Sbjct: 528 RRLMAEDEEGY---------------RKLIDQKKDKR-LAYLLQQTDEYVANLTELVRQH 571
Query: 1328 KGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSP 1387
K A E+ K KK+K E + P + + + + SD P + V+ +
Sbjct: 572 KAAQVAKEKKKKKKKKKAENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGT 631
Query: 1388 MKKKQKKKEN--KENKEKQMSSRKD-KEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGP 1444
K + E + N +++ R D +E E ++ ++++E+P++ + ++ + P
Sbjct: 632 DAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIP 691
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/91 (21%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 1378 VKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPK-SGDAKSSS 1436
+ +D + + ++K KE+ + S +++EG++E +S+ + K K K +
Sbjct: 1546 IYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKA 1605
Query: 1437 KSKRSQGPVHITAGSEPVPIGEDEDDDLDQE 1467
+ + G + GS P+ D+D + +QE
Sbjct: 1606 QDRLKGGRRRPSRGSRAKPVVSDDDSEEEQE 1636
>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 412 bits (1059), Expect = e-114
Identities = 294/835 (35%), Positives = 426/835 (51%), Gaps = 105/835 (12%)
Query: 484 LRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLS 543
L+ YQ++GL WL + N + ILADEMGLGKTIQTI+ ++YL ++ GPFLI+VPLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 544 TLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDK 603
TL++W EF+ WAP + V Y G +R Q + KFN L+TTYE ++KDK
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVP------QLRSGKFNVLLTTYEYIIKDK 867
Query: 604 TVLGSINWAFLGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 662
+L I W ++ VDE HR+KN L + L + + RLL+TGTPLQN L ELW+LL+F
Sbjct: 868 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNF 927
Query: 663 IMPEKFEFWEDFE-----------EDHGKGRENGY---QSLHKVLEPFLLRRVKKDVEKS 708
++P F+ FE E E + LHKVL PFLLRR+KK+VE
Sbjct: 928 LLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQ 987
Query: 709 LPAKVEQILRVEMSALQKQYY-----KWILTRNYKALAKGTRGSTSGFLNIVMELKKCCN 763
LP KVE +++ +MSALQ+ Y K +L + K +G T +N +M+L+K CN
Sbjct: 988 LPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICN 1047
Query: 764 HCYLIKPPEENEREN-----GQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVR 818
H Y+ + EE+ E+ G L L R+SGK LLD++L +LR ++VL+F QM
Sbjct: 1048 HPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTS 1107
Query: 819 MLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLAS 878
++ I+ +Y + + + RLDG+ K E R L FN GSE F FLLSTRAGGLG+NL S
Sbjct: 1108 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQS 1167
Query: 879 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHL 938
ADTV+IFDSDWNP DLQAQ RAHRIGQ+ +V + RL T +VEE+I+ AK K+ +D
Sbjct: 1168 ADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1227
Query: 939 VIQ--RMDTTG---------RTILEN-----------NSGRSN---------------SN 961
VIQ D + ILE+ SG ++
Sbjct: 1228 VIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEE 1287
Query: 962 PFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLS-- 1019
P KEE + E E MD+D A + + DEL S
Sbjct: 1288 PPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWI 1347
Query: 1020 ---QFKVANFATMEDEEEL-----EERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLP 1071
+V E+EE++ R D+ + + E+Q K EE +E+EE +
Sbjct: 1348 IKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEE--EVR 1405
Query: 1072 RIRSSTKKAQTNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGF 1131
+ +SS K+ + +D+ S T + S + D+ KK K+RGRP + +
Sbjct: 1406 QKKSSRKRKRDSDAGSST--------PTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPN 1457
Query: 1132 TDAEIRRFIKAYKKFG------------LPLERLECIARDAELVDKSVADLKRLGELIHN 1179
++++ + A K+ + L + + EL+ K V D K++ E I N
Sbjct: 1458 LTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPV-DFKKIKERIRN 1516
Query: 1180 SCVSAMQEYEEQ---LKENASEGKGPGKR-RGPTIKISGVQVNVKSIIQHEEEFE 1230
++ + E+ L +NA G +I + V +V+ I+ E++ E
Sbjct: 1517 HKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSE 1571
Score = 40.0 bits (92), Expect = 0.021
Identities = 53/240 (22%), Positives = 104/240 (43%), Gaps = 25/240 (10%)
Query: 2 MRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE 61
+R K S++ + +S+ + S + D S+ + ++G P + ++ +
Sbjct: 1404 VRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMK 1463
Query: 62 SQSES----ESESAGSKSQPV---LPEAKEKPASKK--ERIADVKKMWEEYPDVYGVRRS 112
++ + S+G + V LP KE P + + D KK+ E + + R
Sbjct: 1464 KIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRN-HKYRSL 1522
Query: 113 NRSR-------QEPSRFNIKE----EASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQE 161
N Q FN++ E S +S R ++++K++ + E SE+E+E
Sbjct: 1523 NDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVR--QKIEKEDDSEGEESEEEEE 1580
Query: 162 QGTSAESEPEQKKVKARRPVPRRTVPKPRVK-KQPKTQRGKRKKQDSSDEDDDDDEAPKR 220
G SE E + VK + + R+ + R+K + + RG R K SD+D ++++ R
Sbjct: 1581 -GEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDR 1639
Score = 37.0 bits (84), Expect = 0.18
Identities = 42/185 (22%), Positives = 79/185 (42%), Gaps = 35/185 (18%)
Query: 1287 DPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKPRV 1346
+P LK D++ D + + + + +R L+++ EEA+ KRKPR+
Sbjct: 1287 EPPLKEEDEV----PDDETVNQMIARHEEEFDLFMRMDLDRRR-----EEARNPKRKPRL 1337
Query: 1347 KKENKVP-----------RL---KEEHGIELSSPRH------SDNPSEE---GEVKDDGL 1383
+E+++P RL +EE + RH SD+ +E+ +++ L
Sbjct: 1338 MEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTL 1397
Query: 1384 EKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQG 1443
E+ + +QKK K ++ S + R K + K++ K G + K S
Sbjct: 1398 EEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPA---EKLSPN 1454
Query: 1444 PVHIT 1448
P ++T
Sbjct: 1455 PPNLT 1459
Score = 34.3 bits (77), Expect = 1.1
Identities = 49/240 (20%), Positives = 97/240 (40%), Gaps = 32/240 (13%)
Query: 1216 QVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDS-------- 1267
Q + SI+QH ++F+ H+S+ K LT V H + E + ++
Sbjct: 473 QEYLNSILQHAKDFKEYHRSV-----TGKIQKLTKAVATYHANTEREQKKENERIEKERM 527
Query: 1268 RLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEK 1327
R L+ E GY K++ + DK+ LQ +Y+ L +
Sbjct: 528 RRLMAEDEEGY---------------RKLIDQKKDKR-LAYLLQQTDEYVANLTELVRQH 571
Query: 1328 KGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSP 1387
K A E+ K KK+K E + P + + + + SD P + V+ +
Sbjct: 572 KAAQVAKEKKKKKKKKKAENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGT 631
Query: 1388 MKKKQKKKEN--KENKEKQMSSRKD-KEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGP 1444
K + E + N +++ R D +E E ++ ++++E+P++ + ++ + P
Sbjct: 632 DAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIP 691
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/91 (21%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 1378 VKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPK-SGDAKSSS 1436
+ +D + + ++K KE+ + S +++EG++E +S+ + K K K +
Sbjct: 1546 IYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKA 1605
Query: 1437 KSKRSQGPVHITAGSEPVPIGEDEDDDLDQE 1467
+ + G + GS P+ D+D + +QE
Sbjct: 1606 QDRLKGGRRRPSRGSRAKPVVSDDDSEEEQE 1636
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 408 bits (1049), Expect = e-113
Identities = 293/808 (36%), Positives = 428/808 (52%), Gaps = 97/808 (12%)
Query: 470 LKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQ 529
++KQ A L N L+ YQL+GL W+ + N + ILADEMGLGKTIQTI+ ++YL
Sbjct: 712 VEKQSALL--INGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEH 769
Query: 530 HQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKF 589
+L GP+LI+VPLSTL++W EF+ WAP + + Y G R ++ Q + KF
Sbjct: 770 KRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVP------QLRSGKF 823
Query: 590 NALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTP 648
N L+TTYE ++KDK +L I W ++ VDE HR+KN L + L + + R+L+TGTP
Sbjct: 824 NVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTP 883
Query: 649 LQNSLKELWSLLHFIMPEKFEFWEDFE-----------EDHGKGRENGY---QSLHKVLE 694
LQN L ELW+LL+F++P F+ FE E E + LHKVL
Sbjct: 884 LQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLR 943
Query: 695 PFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYY-----KWILTRNYKALAKGTRGSTS 749
PFLLRR+KK+VE LP KVE +++ +MSALQK Y K IL + K +G
Sbjct: 944 PFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAK 1003
Query: 750 GFLNIVMELKKCCNHCYLIKPPEENERE-----NGQEILLSLIRSSGKLILLDKLLTRLR 804
+N +M+L+K CNH Y+ + EE+ E NG L R+SGK LLD++L +LR
Sbjct: 1004 TLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLR 1063
Query: 805 ERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFL 864
+RVL+F QM ++ I+ +Y +++ + RLDG+ K E R L FN GS+ F FL
Sbjct: 1064 ATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFL 1123
Query: 865 LSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEE 924
LSTRAGGLG+NL +ADTVVIFDSDWNP DLQAQ RAHRIGQ+ +V + RL T +VEE+
Sbjct: 1124 LSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEK 1183
Query: 925 IIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFKELE 984
I+ AK K+ +D VIQ + + S F L AIL E E
Sbjct: 1184 ILAAAKYKLNVDQKVIQ------AGMFDQKSSSHERRAF----LQAIL---------EHE 1224
Query: 985 GEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWD 1044
E E E+ DE L N++ +E ++ ED + +P +
Sbjct: 1225 EENEEEDEVPDDETL-------NQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEE 1277
Query: 1045 EIIPEEQRKKVEEEER---QKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSAS 1101
+ +P K E ER ++E E+I+ R S ++ + SD+ TE + +
Sbjct: 1278 DELPSWIIKDDAEVERLTCEEEEEKIFG----RGSRQRRDVDYSDALTEKQ---WLRAIE 1330
Query: 1102 ESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAE 1161
+ E+ +++ + K+R R R+V KD + D E KA K+ G P AE
Sbjct: 1331 DGNLEEMEEEVRLKKRKRRRNVDKDPAK--EDVE-----KAKKRRGRP---------PAE 1374
Query: 1162 LVDKSVADLKRLGELIHNSCVSAMQEYE-EQLKENAS---EGKGPGKRRGPTIKISGVQV 1217
+ + L + I ++ ++ E++ N+ EG G+ ++S V +
Sbjct: 1375 KLSPNPPKLTKQMNAIIDTVINYKDRCNVEKVPSNSQLEIEGNSSGR------QLSEVFI 1428
Query: 1218 NVKSIIQHEEEFEMLHKSIPVDPEEKKK 1245
+ S + E +E++ K PVD ++ K+
Sbjct: 1429 QLPSRKELPEYYELIRK--PVDFKKIKE 1454
Score = 38.9 bits (89), Expect = 0.046
Identities = 60/234 (25%), Positives = 96/234 (41%), Gaps = 25/234 (10%)
Query: 3 RNKDKSQ-EEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE 61
RN DK +ED +E+ S + + D + N S
Sbjct: 1350 RNVDKDPAKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDRCNVEKVPSN 1409
Query: 62 SQSESESESAGSKSQPV---LPEAKEKPASKK--ERIADVKKMWE-----EYPDVYGVRR 111
SQ E E S+G + V LP KE P + + D KK+ E +Y + + +
Sbjct: 1410 SQLEIEGNSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEK 1469
Query: 112 SNRSR-QEPSRFNIKEEASSGSESG----SPKRRGQRQLKKQEKWKQEPSEDEQEQGTSA 166
FN+ E S E S + ++++ K+E+ + E +E+E+E+
Sbjct: 1470 DVMLLCHNAQTFNL--EGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDEE- 1526
Query: 167 ESEPEQKKVKARRPVPRRT---VPKPRVKKQPKTQRGKRKKQDSS-DEDDDDDE 216
ESE E K VK + + ++ K + KK+P RGK K S D D++ DE
Sbjct: 1527 ESESEAKSVKVKIKLNKKDDKGRDKGKGKKRP--NRGKAKPVVSDFDSDEEQDE 1578
Score = 32.0 bits (71), Expect = 5.7
Identities = 62/298 (20%), Positives = 118/298 (39%), Gaps = 32/298 (10%)
Query: 1216 QVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRV---KAAHFDVEWGVEDDSRLLLG 1272
Q + SI+QH ++F+ H+S+ ++ K T + + E ++ R L+
Sbjct: 449 QEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA 508
Query: 1273 IYEHGYGNWELIKTDPE----LKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEKK 1328
E GY K D L+ TD+ + T+ + KQ Q + + RK ++
Sbjct: 509 EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEE 568
Query: 1329 GAVTGGEEAKLKKRKPRVKKENKVPRL-----KEEHGIELSSPRHSDNPSEEGEVKDDGL 1383
A GGE A +P + + +++ L E G L P + + D L
Sbjct: 569 NA-EGGESALGPDGEP-IDESSQMSDLPVKVTHTETGKVLFGPE-----APKASQLDAWL 621
Query: 1384 EKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQG 1443
E +P + + +++E S +E D+E + S+ + E+ D S S++
Sbjct: 622 EMNPGYEVAPRSDSEE------SDSDYEEEDEEEESSRQETEEKILLDPNSEEVSEKDAK 675
Query: 1444 PVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEH 1501
+ TA +D DD+ + + + V A+ + + L + L+H
Sbjct: 676 QIIETA-------KQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKH 726
Score = 31.6 bits (70), Expect = 7.4
Identities = 20/78 (25%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 1389 KKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHIT 1448
++K K+E E++ + +D+E + KS K K D K K K + P
Sbjct: 1503 RQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNR-- 1560
Query: 1449 AGSEPVPIGEDEDDDLDQ 1466
++PV D D++ D+
Sbjct: 1561 GKAKPVVSDFDSDEEQDE 1578
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 408 bits (1048), Expect = e-113
Identities = 274/708 (38%), Positives = 387/708 (54%), Gaps = 76/708 (10%)
Query: 470 LKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQ 529
++KQ A L N L+ YQL+GL W+ + N + ILADEMGLGKTIQTI+ ++YL
Sbjct: 712 VEKQSALL--INGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEH 769
Query: 530 HQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKF 589
+L GP+LI+VPLSTL++W EF+ WAP + + Y G R ++ Q + KF
Sbjct: 770 KRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVP------QLRSGKF 823
Query: 590 NALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTP 648
N L+TTYE ++KDK +L I W ++ VDE HR+KN L + L + + R+L+TGTP
Sbjct: 824 NVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTP 883
Query: 649 LQNSLKELWSLLHFIMPEKFEFWEDFE-----------EDHGKGRENGY---QSLHKVLE 694
LQN L ELW+LL+F++P F+ FE E E + LHKVL
Sbjct: 884 LQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLR 943
Query: 695 PFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYY-----KWILTRNYKALAKGTRGSTS 749
PFLLRR+KK+VE LP KVE +++ +MSALQK Y K IL + K +G
Sbjct: 944 PFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAK 1003
Query: 750 GFLNIVMELKKCCNHCYLIKPPEENERE-----NGQEILLSLIRSSGKLILLDKLLTRLR 804
+N +M+L+K CNH Y+ + EE+ E NG L R+SGK LLD++L +LR
Sbjct: 1004 TLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLR 1063
Query: 805 ERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFL 864
+RVL+F QM ++ I+ +Y +++ + RLDG+ K E R L FN GS+ F FL
Sbjct: 1064 ATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFL 1123
Query: 865 LSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEE 924
LSTRAGGLG+NL +ADTVVIFDSDWNP DLQAQ RAHRIGQ+ +V + RL T +VEE+
Sbjct: 1124 LSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEK 1183
Query: 925 IIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPFNKEELTAILKFGAEDLFKELE 984
I+ AK K+ +D VIQ + + S F L AIL E E
Sbjct: 1184 ILAAAKYKLNVDQKVIQ------AGMFDQKSSSHERRAF----LQAIL---------EHE 1224
Query: 985 GEESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFATMEDEEELEERPHKDWD 1044
E E E+ DE L N++ +E ++ ED + +P +
Sbjct: 1225 EENEEEDEVPDDETL-------NQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEE 1277
Query: 1045 EIIPEEQRKKVEEEER---QKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSAS 1101
+ +P K E ER ++E E+I+ R S ++ + SD+ TE + +
Sbjct: 1278 DELPSWIIKDDAEVERLTCEEEEEKIFG----RGSRQRRDVDYSDALTEKQ---WLRAIE 1330
Query: 1102 ESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFGLP 1149
+ E+ +++ + K+R R R+V KD + D E KA K+ G P
Sbjct: 1331 DGNLEEMEEEVRLKKRKRRRNVDKDPAK--EDVE-----KAKKRRGRP 1371
Score = 35.8 bits (81), Expect = 0.39
Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 6/81 (7%)
Query: 140 RGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRT---VPKPRVKKQPK 196
+ RQ +E+ ++ S +E+E+ ESE E K VK + + ++ K + KK+P
Sbjct: 1482 KSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRP- 1540
Query: 197 TQRGKRKKQDSS-DEDDDDDE 216
RGK K S D D++ DE
Sbjct: 1541 -NRGKAKPVVSDFDSDEEQDE 1560
Score = 32.0 bits (71), Expect = 5.7
Identities = 62/298 (20%), Positives = 118/298 (39%), Gaps = 32/298 (10%)
Query: 1216 QVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRV---KAAHFDVEWGVEDDSRLLLG 1272
Q + SI+QH ++F+ H+S+ ++ K T + + E ++ R L+
Sbjct: 449 QEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMA 508
Query: 1273 IYEHGYGNWELIKTDPE----LKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEKK 1328
E GY K D L+ TD+ + T+ + KQ Q + + RK ++
Sbjct: 509 EDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEE 568
Query: 1329 GAVTGGEEAKLKKRKPRVKKENKVPRL-----KEEHGIELSSPRHSDNPSEEGEVKDDGL 1383
A GGE A +P + + +++ L E G L P + + D L
Sbjct: 569 NA-EGGESALGPDGEP-IDESSQMSDLPVKVTHTETGKVLFGPE-----APKASQLDAWL 621
Query: 1384 EKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQG 1443
E +P + + +++E S +E D+E + S+ + E+ D S S++
Sbjct: 622 EMNPGYEVAPRSDSEE------SDSDYEEEDEEEESSRQETEEKILLDPNSEEVSEKDAK 675
Query: 1444 PVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQLDKPDKGLNVQEQLEH 1501
+ TA +D DD+ + + + V A+ + + L + L+H
Sbjct: 676 QIIETA-------KQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKH 726
Score = 31.6 bits (70), Expect = 7.4
Identities = 20/78 (25%), Positives = 35/78 (44%), Gaps = 2/78 (2%)
Query: 1389 KKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVHIT 1448
++K K+E E++ + +D+E + KS K K D K K K + P
Sbjct: 1485 RQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNR-- 1542
Query: 1449 AGSEPVPIGEDEDDDLDQ 1466
++PV D D++ D+
Sbjct: 1543 GKAKPVVSDFDSDEEQDE 1560
>gi|148612870 chromodomain helicase DNA binding protein 1-like [Homo
sapiens]
Length = 897
Score = 405 bits (1040), Expect = e-112
Identities = 258/657 (39%), Positives = 375/657 (57%), Gaps = 50/657 (7%)
Query: 478 GGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFL 537
G + LR YQLEG+NWLA + N IL DEMGLGKT QTI+ YL + GPFL
Sbjct: 40 GLTGIHLRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFL 99
Query: 538 IVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYE 597
I+ PLS L++W+ E + +AP ++ V Y GD R +++ + +F+ L+TTYE
Sbjct: 100 ILCPLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQQ-----DLKQESRFHVLLTTYE 154
Query: 598 ILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELW 657
I LKD + L S W+ L VDEAHRLKN SLL+KTL +F LL+TGTP+QNSL+EL+
Sbjct: 155 ICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELY 214
Query: 658 SLLHFIMPEKF---------EFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKS 708
SLL F+ P+ F + ++D E++ E LHK+L+PFLLRRVK +V
Sbjct: 215 SLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASE-----LHKLLQPFLLRRVKAEVATE 269
Query: 709 LPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLI 768
LP K E ++ MSALQK+YYK IL ++ A T NI+ +L+KC +H YL
Sbjct: 270 LPKKTEVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVK-LQNILSQLRKCVDHPYLF 328
Query: 769 KPPEENERENGQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLT 828
E E G L +SGKL LLDKLL L G+RVL+FSQM +MLDIL +Y+
Sbjct: 329 DGVEPEPFEVGDH----LTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMD 384
Query: 829 IKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSD 888
+ Y ++R+DGS++GE R A+ +F F FLLSTRAGG+G+NL +ADTV+ DSD
Sbjct: 385 YRGYSYERVDGSVRGEERHLAIKNFGQQPI--FVFLLSTRAGGVGMNLTAADTVIFVDSD 442
Query: 889 WNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGR 948
+NPQNDLQA ARAHRIGQ K V + RL+ + TVEE + +A K+ L +++I+ G
Sbjct: 443 FNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIE----GGH 498
Query: 949 TILENNSGRSNSNPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENE 1008
L ++++ +L+ ILKFG + L L E S E+D++ I L ET++ +
Sbjct: 499 FTLGAQKPAADAD----LQLSEILKFGLDKL---LASEGSTMDEIDLESI--LGETKDGQ 549
Query: 1009 VSTSA--------TDELLSQFKVANFATMEDEEELEERPHKDWDEIIPEEQR--KKVEEE 1058
+ A D+ + + F + +E + K +++++ ++ +K +E
Sbjct: 550 WVSDALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQE 609
Query: 1059 ERQKELEEIYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETEDSDDDKKPK 1115
R + ++P + + K + S + E RQ +R A+ ++ K+ K
Sbjct: 610 GRSLRNKGSVLIPGLVEGSTKRKRVLSPEELED-RQKKRQEAAAKRRRLIEEKKRQK 665
>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform A [Homo sapiens]
Length = 1679
Score = 395 bits (1016), Expect = e-109
Identities = 290/857 (33%), Positives = 426/857 (49%), Gaps = 117/857 (13%)
Query: 484 LRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLS 543
L+ YQ++GL WL + N + ILADEMGLGKTIQTI+ ++YL ++ GPFLI+VPLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 544 TLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDK 603
TL++W EF+ WAP + V Y G +R Q + KFN L+TTYE ++KDK
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVP------QLRSGKFNVLLTTYEYIIKDK 867
Query: 604 TVLGSINWAFLGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 662
+L I W ++ VDE HR+KN L + L + + RLL+TGTPLQN L ELW+LL+F
Sbjct: 868 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNF 927
Query: 663 IMPEKFEFWEDFE-----------EDHGKGRENGY---QSLHKVLEPFLLRRVKKDVEKS 708
++P F+ FE E E + LHKVL PFLLRR+KK+VE
Sbjct: 928 LLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQ 987
Query: 709 LPAKVEQILRVEMSALQKQYY-----KWILTRNYKALAKGTRGSTSGFLNIVMELKKCCN 763
LP KVE +++ +MSALQ+ Y K +L + K +G T +N +M+L+K CN
Sbjct: 988 LPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICN 1047
Query: 764 HCYLIKPPEENEREN-----GQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVR 818
H Y+ + EE+ E+ G L L R+SGK LLD++L +LR ++VL+F QM
Sbjct: 1048 HPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTS 1107
Query: 819 MLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLAS 878
++ I+ +Y + + + RLDG+ K E R L FN GSE F FLLSTRAGGLG+NL S
Sbjct: 1108 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQS 1167
Query: 879 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHL 938
ADTV+IFDSDWNP DLQAQ RAHRIGQ+ +V + RL T +VEE+I+ AK K+ +D
Sbjct: 1168 ADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1227
Query: 939 VIQ--RMDTTG---------RTILEN-----------NSGRSN---------------SN 961
VIQ D + ILE+ SG ++
Sbjct: 1228 VIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEE 1287
Query: 962 PFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEVSTSATDELLS-- 1019
P KEE + E E MD+D A + + DEL S
Sbjct: 1288 PPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWI 1347
Query: 1020 ---QFKVANFATMEDEEEL-----EERPHKDWDEIIPEEQ-RKKVEEEERQKELEEI--- 1067
+V E+EE++ R D+ + + E+Q KK+ ++ +
Sbjct: 1348 IKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQWLKKITGKDIHDTASSVARG 1407
Query: 1068 -------YMLPRIRSSTKKAQTNDSDSDT---ESKRQAQRSSASESET--------EDSD 1109
R + ++ + + + +S R+ +R S + S T + D
Sbjct: 1408 LQFQRGLQFCTRASKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDD 1467
Query: 1110 DDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKFG------------LPLERLECIA 1157
+ KK K+RGRP + + ++++ + A K+ + L + +
Sbjct: 1468 ESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELP 1527
Query: 1158 RDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQ---LKENASEGKGPGKR-RGPTIKIS 1213
EL+ K V D K++ E I N ++ + E+ L +NA G +I +
Sbjct: 1528 EYYELIRKPV-DFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQ 1586
Query: 1214 GVQVNVKSIIQHEEEFE 1230
V +V+ I+ E++ E
Sbjct: 1587 SVFTSVRQKIEKEDDSE 1603
Score = 40.0 bits (92), Expect = 0.021
Identities = 53/240 (22%), Positives = 104/240 (43%), Gaps = 25/240 (10%)
Query: 2 MRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE 61
+R K S++ + +S+ + S + D S+ + ++G P + ++ +
Sbjct: 1436 VRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMK 1495
Query: 62 SQSES----ESESAGSKSQPV---LPEAKEKPASKK--ERIADVKKMWEEYPDVYGVRRS 112
++ + S+G + V LP KE P + + D KK+ E + + R
Sbjct: 1496 KIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRN-HKYRSL 1554
Query: 113 NRSR-------QEPSRFNIKE----EASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQE 161
N Q FN++ E S +S R ++++K++ + E SE+E+E
Sbjct: 1555 NDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVR--QKIEKEDDSEGEESEEEEE 1612
Query: 162 QGTSAESEPEQKKVKARRPVPRRTVPKPRVK-KQPKTQRGKRKKQDSSDEDDDDDEAPKR 220
G SE E + VK + + R+ + R+K + + RG R K SD+D ++++ R
Sbjct: 1613 -GEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDR 1671
Score = 34.3 bits (77), Expect = 1.1
Identities = 49/240 (20%), Positives = 97/240 (40%), Gaps = 32/240 (13%)
Query: 1216 QVNVKSIIQHEEEFEMLHKSIPVDPEEKKKYCLTCRVKAAHFDVEWGVEDDS-------- 1267
Q + SI+QH ++F+ H+S+ K LT V H + E + ++
Sbjct: 473 QEYLNSILQHAKDFKEYHRSV-----TGKIQKLTKAVATYHANTEREQKKENERIEKERM 527
Query: 1268 RLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQGKQLQTRADYLLKLLRKGLEK 1327
R L+ E GY K++ + DK+ LQ +Y+ L +
Sbjct: 528 RRLMAEDEEGY---------------RKLIDQKKDKR-LAYLLQQTDEYVANLTELVRQH 571
Query: 1328 KGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSP 1387
K A E+ K KK+K E + P + + + + SD P + V+ +
Sbjct: 572 KAAQVAKEKKKKKKKKKAENAEGQTPAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGT 631
Query: 1388 MKKKQKKKEN--KENKEKQMSSRKD-KEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGP 1444
K + E + N +++ R D +E E ++ ++++E+P++ + ++ + P
Sbjct: 632 DAPKAGQLEAWLEMNPGYEVAPRSDSEESGSEEEEEEEEEEQPQAAQPPTLPVEEKKKIP 691
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/91 (21%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 1378 VKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEKPK-SGDAKSSS 1436
+ +D + + ++K KE+ + S +++EG++E +S+ + K K K +
Sbjct: 1578 IYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKA 1637
Query: 1437 KSKRSQGPVHITAGSEPVPIGEDEDDDLDQE 1467
+ + G + GS P+ D+D + +QE
Sbjct: 1638 QDRLKGGRRRPSRGSRAKPVVSDDDSEEEQE 1668
>gi|21914927 helicase, lymphoid-specific [Homo sapiens]
Length = 838
Score = 307 bits (786), Expect = 7e-83
Identities = 239/776 (30%), Positives = 382/776 (49%), Gaps = 115/776 (14%)
Query: 327 LQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAV 386
++QQ+++ KK E ++K++ +K GK S + E ++ ++ Y I E
Sbjct: 86 MEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASEEKPVMRKKRGREDESYNISE----- 140
Query: 387 KTSKSTLGQTDFPAHSRKPAPSNEPEYLCKW-MGLPYSECSWEDEALIGKKFQNCIDSFH 445
+ + + + ++K NE E + + + + + ++I + +
Sbjct: 141 -----VMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSNSIIKDRLSETV---- 191
Query: 446 SRNNSKTI--PTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNN 503
R N+K P R+C V ++ + GG +R YQ+EG+ WL W
Sbjct: 192 -RQNTKFFFDPVRKCNGQP-----VPFQQPKHFTGGV---MRWYQVEGMEWLRMLWENGI 242
Query: 504 SVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVV 563
+ ILADEMGLGKT+Q I+ ++ + Q + GPFL+ PLSTL +W EF+ + P+I ++
Sbjct: 243 NGILADEMGLGKTVQCIATIALMI-QRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTML 301
Query: 564 YIGDLMSRNTIREYEWIHSQTKRLKFNALITTYEILLKDKTVLGSINWAFLGVDEAHRLK 623
Y G R + + T ++ +IT++EI ++D+ L W +L VDE HR+K
Sbjct: 302 YHGTQEERQKLVRNIYKRKGTLQIH-PVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK 360
Query: 624 NDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPE------KFEFWEDF--- 674
N L + L F ++++LL+TGTPLQN+L ELWSLL+F++P+ FE W D
Sbjct: 361 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL 420
Query: 675 ----EEDHGKGRE-NGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQYY 729
E+ K RE N LH++L PFLLRR+K DV +P K E ++ +S Q+ +Y
Sbjct: 421 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY 480
Query: 730 KWILTRNYKALAKGTRGST-------------------SGFLNIVMELKKCCNHCYLIKP 770
I+ R + + T S + EL+K + I+P
Sbjct: 481 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQ---IQP 537
Query: 771 PEENERE--------------NGQEILLSLIRSSGKLILLD----------KLLTRLRER 806
+ ER Q I++ L + L++ K+ L
Sbjct: 538 EVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTN 597
Query: 807 GNRVLIFSQMV-----------------RMLDILAEYLTIKHYPFQRLDGSIKGEIRKQA 849
+ LI +M+ MLDIL +Y ++ + F RLDGS+ R++
Sbjct: 598 SGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKN 657
Query: 850 LDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQ 909
+ FN D E F FL+STRAGGLGINL +ADTV+I+DSDWNPQ+DLQAQ R HRIGQ K
Sbjct: 658 MHSFNTD-PEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKP 716
Query: 910 VNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPF-NKEEL 968
V +YRLVT T++++I+ERA K L+ L+I + G SG + S F + +EL
Sbjct: 717 VVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKG-----GQSGLNLSKNFLDPKEL 771
Query: 969 TAILKFGAEDLFKELEG-EESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKV 1023
+LK + D +E++G E + D++ +L ++ + ++ E + FK+
Sbjct: 772 MELLK--SRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKI 825
Score = 31.2 bits (69), Expect = 9.7
Identities = 14/50 (28%), Positives = 27/50 (54%)
Query: 208 SDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQ 257
S E + + +P + +RR K+++Y + DDF + + LI VD ++
Sbjct: 494 SSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRER 543
>gi|190358536 SWI/SNF-related, matrix-associated actin-dependent
regulator of chromatin, subfamily a, containing DEAD/H
box 1 isoform a [Homo sapiens]
Length = 1028
Score = 298 bits (762), Expect = 4e-80
Identities = 191/522 (36%), Positives = 286/522 (54%), Gaps = 64/522 (12%)
Query: 472 KQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQ 531
+QP+ L ++L L+ YQ GLNWLA + ILADEMGLGKTIQ I+FL+YL+ +
Sbjct: 486 EQPSILN-QSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEGN 544
Query: 532 LYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNA 591
GP LIVVP ST+ +W RE +W P + V+ Y G R IR IHS+ + +N
Sbjct: 545 -NGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFN--IHSRYE--DYNV 599
Query: 592 LITTYEILLK---DKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTP 648
++TTY + D+++ + + DE H LKN S+ Y+ L+ +N+RLL+TGTP
Sbjct: 600 IVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTP 659
Query: 649 LQNSLKELWSLLHFIMPEKF--EFWEDFEEDHGKGRENGYQSLH---------KVLEPFL 697
+QN+L EL SLL+F+MP F E K + QS++ ++++PF+
Sbjct: 660 VQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFI 719
Query: 698 LRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVME 757
LRRVK++V K LP K ++I MS Q+Q Y + R K++ + N++M+
Sbjct: 720 LRRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQ 779
Query: 758 LKKCCNHCYL-----------------IKPPEENERE----------------------- 777
L+K NH L +K P E
Sbjct: 780 LRKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQY 839
Query: 778 ---NGQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPF 834
N ++ + LI SGK +L +L+ L+++G+RV++FSQ MLDIL L + +
Sbjct: 840 RHINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRY 899
Query: 835 QRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQND 894
RLDG + R +D FN D + F FLLST+AGGLGINL SA+ V++ D D NP ND
Sbjct: 900 LRLDGKTQISERIHLIDEFNTD-MDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYND 958
Query: 895 LQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLD 936
QA+ R HR+GQ K+V + +L+++GT+EE +++ ++K+ L+
Sbjct: 959 KQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLE 1000
Score = 33.1 bits (74), Expect = 2.5
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 21/136 (15%)
Query: 31 SDSGSQSESEQGSDPGS------GHGSESNSSSESSESQSESESESAGSKSQPVLPEAKE 84
S S E ++ +D S HG ESN S+ESS + + ES VL KE
Sbjct: 211 SSSSEPYEEDEFNDDQSIKKTRLDHGEESNESAESSSNWEKQES--------IVLKLQKE 262
Query: 85 KPASKKERIADVKK----MWEEYPDVYGVRRSNRSRQEPSRFNIK--EEASSGSESGSPK 138
P K+ + +V K M+ E + V ++ Q S+ + +E SS S++ PK
Sbjct: 263 FPNFDKQELREVLKEHEWMYTEALESLKVFAEDQDMQYVSQSEVPNGKEVSSRSQN-YPK 321
Query: 139 RRGQRQLKKQEKWKQE 154
+ +LK++ K +
Sbjct: 322 NATKTKLKQKFSMKAQ 337
>gi|190358532 SWI/SNF-related, matrix-associated actin-dependent
regulator of chromatin, subfamily a, containing DEAD/H
box 1 isoform a [Homo sapiens]
Length = 1028
Score = 298 bits (762), Expect = 4e-80
Identities = 191/522 (36%), Positives = 286/522 (54%), Gaps = 64/522 (12%)
Query: 472 KQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQ 531
+QP+ L ++L L+ YQ GLNWLA + ILADEMGLGKTIQ I+FL+YL+ +
Sbjct: 486 EQPSILN-QSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEGN 544
Query: 532 LYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNA 591
GP LIVVP ST+ +W RE +W P + V+ Y G R IR IHS+ + +N
Sbjct: 545 -NGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFN--IHSRYE--DYNV 599
Query: 592 LITTYEILLK---DKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTP 648
++TTY + D+++ + + DE H LKN S+ Y+ L+ +N+RLL+TGTP
Sbjct: 600 IVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTP 659
Query: 649 LQNSLKELWSLLHFIMPEKF--EFWEDFEEDHGKGRENGYQSLH---------KVLEPFL 697
+QN+L EL SLL+F+MP F E K + QS++ ++++PF+
Sbjct: 660 VQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFI 719
Query: 698 LRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVME 757
LRRVK++V K LP K ++I MS Q+Q Y + R K++ + N++M+
Sbjct: 720 LRRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQ 779
Query: 758 LKKCCNHCYL-----------------IKPPEENERE----------------------- 777
L+K NH L +K P E
Sbjct: 780 LRKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQY 839
Query: 778 ---NGQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPF 834
N ++ + LI SGK +L +L+ L+++G+RV++FSQ MLDIL L + +
Sbjct: 840 RHINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRY 899
Query: 835 QRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQND 894
RLDG + R +D FN D + F FLLST+AGGLGINL SA+ V++ D D NP ND
Sbjct: 900 LRLDGKTQISERIHLIDEFNTD-MDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYND 958
Query: 895 LQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLD 936
QA+ R HR+GQ K+V + +L+++GT+EE +++ ++K+ L+
Sbjct: 959 KQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLE 1000
Score = 33.1 bits (74), Expect = 2.5
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 21/136 (15%)
Query: 31 SDSGSQSESEQGSDPGS------GHGSESNSSSESSESQSESESESAGSKSQPVLPEAKE 84
S S E ++ +D S HG ESN S+ESS + + ES VL KE
Sbjct: 211 SSSSEPYEEDEFNDDQSIKKTRLDHGEESNESAESSSNWEKQES--------IVLKLQKE 262
Query: 85 KPASKKERIADVKK----MWEEYPDVYGVRRSNRSRQEPSRFNIK--EEASSGSESGSPK 138
P K+ + +V K M+ E + V ++ Q S+ + +E SS S++ PK
Sbjct: 263 FPNFDKQELREVLKEHEWMYTEALESLKVFAEDQDMQYVSQSEVPNGKEVSSRSQN-YPK 321
Query: 139 RRGQRQLKKQEKWKQE 154
+ +LK++ K +
Sbjct: 322 NATKTKLKQKFSMKAQ 337
>gi|190358534 SWI/SNF-related, matrix-associated actin-dependent
regulator of chromatin, subfamily a, containing DEAD/H
box 1 isoform b [Homo sapiens]
Length = 1026
Score = 295 bits (754), Expect = 4e-79
Identities = 191/522 (36%), Positives = 286/522 (54%), Gaps = 66/522 (12%)
Query: 472 KQPAYLGGENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQHQ 531
+QP+ L ++L L+ YQ GLNWLA + ILADEMGLGKTIQ I+FL+YL+ +
Sbjct: 486 EQPSILN-QSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEGN 544
Query: 532 LYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNA 591
GP LIVVP ST+ +W RE +W P + V+ Y G R IR IHS+ + +N
Sbjct: 545 -NGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFN--IHSRYE--DYNV 599
Query: 592 LITTYEILLK---DKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTP 648
++TTY + D+++ + + DE H LKN S+ Y+ L+ +N+RLL+TGTP
Sbjct: 600 IVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTP 659
Query: 649 LQNSLKELWSLLHFIMPEKF--EFWEDFEEDHGKGRENGYQSLH---------KVLEPFL 697
+QN+L EL SLL+F+MP F E K + QS++ ++++PF+
Sbjct: 660 VQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFI 719
Query: 698 LRRVKKDVEKSLPAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVME 757
LRRVK++V K LP K ++I MS Q+Q Y + R K++ + N++M+
Sbjct: 720 LRRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSI--NNLEKNTEMCNVMMQ 777
Query: 758 LKKCCNHCYL-----------------IKPPEENERE----------------------- 777
L+K NH L +K P E
Sbjct: 778 LRKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQY 837
Query: 778 ---NGQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPF 834
N ++ + LI SGK +L +L+ L+++G+RV++FSQ MLDIL L + +
Sbjct: 838 RHINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRY 897
Query: 835 QRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQND 894
RLDG + R +D FN D + F FLLST+AGGLGINL SA+ V++ D D NP ND
Sbjct: 898 LRLDGKTQISERIHLIDEFNTD-MDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYND 956
Query: 895 LQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLD 936
QA+ R HR+GQ K+V + +L+++GT+EE +++ ++K+ L+
Sbjct: 957 KQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLE 998
Score = 33.1 bits (74), Expect = 2.5
Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 21/136 (15%)
Query: 31 SDSGSQSESEQGSDPGS------GHGSESNSSSESSESQSESESESAGSKSQPVLPEAKE 84
S S E ++ +D S HG ESN S+ESS + + ES VL KE
Sbjct: 211 SSSSEPYEEDEFNDDQSIKKTRLDHGEESNESAESSSNWEKQES--------IVLKLQKE 262
Query: 85 KPASKKERIADVKK----MWEEYPDVYGVRRSNRSRQEPSRFNIK--EEASSGSESGSPK 138
P K+ + +V K M+ E + V ++ Q S+ + +E SS S++ PK
Sbjct: 263 FPNFDKQELREVLKEHEWMYTEALESLKVFAEDQDMQYVSQSEVPNGKEVSSRSQN-YPK 321
Query: 139 RRGQRQLKKQEKWKQE 154
+ +LK++ K +
Sbjct: 322 NATKTKLKQKFSMKAQ 337
>gi|4557565 excision repair cross-complementing rodent repair
deficiency, complementation group 6 [Homo sapiens]
Length = 1493
Score = 264 bits (674), Expect = 7e-70
Identities = 228/800 (28%), Positives = 365/800 (45%), Gaps = 92/800 (11%)
Query: 483 ELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFH----------QHQL 532
+L YQ G+ WL C+ IL DEMGLGKTIQ I+FL+ L + + +
Sbjct: 506 KLFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEG 565
Query: 533 YGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKFNA- 591
GP +IV P + + W +EF W P V + + H + K ++ A
Sbjct: 566 LGPTVIVCPTTVMHQWVKEFHTWWPPFRVAILH---------ETGSYTHKKEKLIRDVAH 616
Query: 592 ----LITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGT 647
LIT+Y + + + +W ++ +DE H+++N ++ + F++ HR++++G+
Sbjct: 617 CHGILITSYSYIRLMQDDISRYDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGS 676
Query: 648 PLQNSLKELWSLLHFIMPEKFE----FWEDFEEDHGKGRENGYQS--------------- 688
P+QN+L+ELWSL FI P K F E F G GY +
Sbjct: 677 PMQNNLRELWSLFDFIFPGKLGTLPVFMEQFSVPITMG---GYSNASPVQVKTAYKCACV 733
Query: 689 LHKVLEPFLLRRVKKDVEKSL--PAKVEQILRVEMSALQ-KQYYKWILTRNYKALAKGTR 745
L + P+LLRR+K DV+ SL P K EQ+L ++ Q K Y ++ ++ + G
Sbjct: 734 LRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVYQNFVDSKEVYRILNGEM 793
Query: 746 GSTSGFLNIVMELKKCCNHCYLIKPPEENER----ENGQEILLSLIRSSGKLILLDKLLT 801
SG + L+K CNH L +N + + +E + SGK+I+++ LL
Sbjct: 794 QIFSGLI----ALRKICNHPDLFSGGPKNLKGLPDDELEEDQFGYWKRSGKMIVVESLLK 849
Query: 802 RLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDF 861
++G RVL+FSQ +MLDIL +L + Y + ++DG+ R+ + +N D S F
Sbjct: 850 IWHKQGQRVLLFSQSRQMLDILEVFLRAQKYTYLKMDGTTTIASRQPLITRYNEDTSI-F 908
Query: 862 CFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTV 921
FLL+TR GGLG+NL A+ VVI+D DWNP D QA+ RA RIGQKKQV +YRL+T GT+
Sbjct: 909 VFLLTTRVGGLGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTI 968
Query: 922 EEEIIERAKKKMVLDHLVIQRMDTTGRTILENNS-----GRSNSNPFNKEELTAILKFGA 976
EE+I R K L + V++ D R ++N ++ + E +AI
Sbjct: 969 EEKIYHRQIFKQFLTNRVLK--DPKQRRFFKSNDLYELFTLTSPDASQSTETSAIFAGTG 1026
Query: 977 EDLFK---ELEGEESEPQEMDIDEILRLAETREN-EVSTSATDELLSQFKVA--NFATME 1030
D+ L+ D D R N V+ + + E S+ K A N T
Sbjct: 1027 SDVQTPKCHLKRRIQPAFGADHDVPKRKKFPASNISVNDATSSEEKSEAKGAEVNAVTSN 1086
Query: 1031 DEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTN----DSD 1086
+ L++ PH + + ++ +EL I +S+ +T+ D
Sbjct: 1087 RSDPLKDDPHMSSNVTSNDRLGEETNAVSGPEELSVISGNGECSNSSGTGKTSMPSGDES 1146
Query: 1087 SDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKDLVEGFTDAEIRRFIKAYKKF 1146
D + +R S+++TE ++K+ + K + + AE K +
Sbjct: 1147 IDEKLGLSYKRERPSQAQTEAFWENKQMENNFYK---HKSKTKHHSVAEEETLEKHLRPK 1203
Query: 1147 GLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQEYEEQLKENASEGKGPGKRR 1206
P C RDA+ + L + + Y++Q EN SE K
Sbjct: 1204 QKPKNSKHC--RDAKFEGTRIPHLVK------------KRRYQKQDSENKSEAKEQSNDD 1249
Query: 1207 GPTIKISGVQVNVKSIIQHE 1226
K+ V V S+++H+
Sbjct: 1250 YVLEKLFKKSVGVHSVMKHD 1269
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,820,296
Number of Sequences: 37866
Number of extensions: 4030212
Number of successful extensions: 52393
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 606
Number of HSP's successfully gapped in prelim test: 1237
Number of HSP's that attempted gapping in prelim test: 23792
Number of HSP's gapped (non-prelim): 18009
length of query: 1828
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1711
effective length of database: 13,817,196
effective search space: 23641222356
effective search space used: 23641222356
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.