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Search of human proteins with 118344454
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|118344454 sperm associated antigen 7 [Homo sapiens]
(227 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|118344454 sperm associated antigen 7 [Homo sapiens] 449 e-126
gi|110349719 titin isoform N2-A [Homo sapiens] 42 6e-04
gi|21361137 nuclear transcription factor, X-box binding 1 isofor... 40 0.002
gi|38261971 cyclic AMP-regulated phosphoprotein, 21 kD isoform 1... 38 0.008
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 37 0.011
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 37 0.011
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 37 0.018
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 37 0.018
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 37 0.018
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 37 0.018
gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] 37 0.018
gi|221219020 NYD-SP11 protein [Homo sapiens] 36 0.024
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 36 0.031
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 36 0.031
gi|31543535 R3H domain containing 1 [Homo sapiens] 36 0.031
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 36 0.031
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 35 0.040
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 35 0.040
gi|7656983 TP53-target gene 5 protein [Homo sapiens] 35 0.053
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 35 0.069
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 35 0.069
gi|148746195 trichohyalin [Homo sapiens] 35 0.069
gi|31982906 cingulin-like 1 [Homo sapiens] 35 0.069
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 34 0.090
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 34 0.090
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 34 0.090
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 34 0.090
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 34 0.090
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 34 0.090
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 34 0.090
>gi|118344454 sperm associated antigen 7 [Homo sapiens]
Length = 227
Score = 449 bits (1154), Expect = e-126
Identities = 227/227 (100%), Positives = 227/227 (100%)
Query: 1 MADLLGSILSSMEKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFI 60
MADLLGSILSSMEKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFI
Sbjct: 1 MADLLGSILSSMEKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFI 60
Query: 61 QDSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDS 120
QDSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDS
Sbjct: 61 QDSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDS 120
Query: 121 YRRGEEWDPQKAEEKRKLKELAQRQEEEAAQQGPVVVSPASDYKDKYSHLIGKGAAKDAA 180
YRRGEEWDPQKAEEKRKLKELAQRQEEEAAQQGPVVVSPASDYKDKYSHLIGKGAAKDAA
Sbjct: 121 YRRGEEWDPQKAEEKRKLKELAQRQEEEAAQQGPVVVSPASDYKDKYSHLIGKGAAKDAA 180
Query: 181 HMLQANKTYGCVPVANKRDTRSIEEAMNEIRAKKRLRQSGEELPPTS 227
HMLQANKTYGCVPVANKRDTRSIEEAMNEIRAKKRLRQSGEELPPTS
Sbjct: 181 HMLQANKTYGCVPVANKRDTRSIEEAMNEIRAKKRLRQSGEELPPTS 227
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 41.6 bits (96), Expect = 6e-04
Identities = 39/158 (24%), Positives = 73/158 (46%), Gaps = 14/158 (8%)
Query: 9 LSSMEKPPSLGDQETRRKA--REQAARLKKLQEQEKQQKV-EFRKRMEKEVSDFIQDSGQ 65
++ E PP E ++A E+ +LK +E+E KV EFRKR+ KE I+
Sbjct: 9653 VTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAP-- 9710
Query: 66 IKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSD-EELDSYRRG 124
K++ QP+ ++ +I+ + L + + Y +E+ D +E + Y
Sbjct: 9711 -KREPQPIKEV--TIMEEKERAYTLEEEAVSVQREEEY-----EEYEEYDYKEFEEYEPT 9762
Query: 125 EEWDPQKAEEKRKLKELAQRQEEEAAQQGPVVVSPASD 162
EE+D + E+R+ + + +E + P+ V P +
Sbjct: 9763 EEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPE 9800
Score = 29.6 bits (65), Expect = 2.2
Identities = 29/155 (18%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 14 KPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPM 73
KP ++E + A K + E++ V K+ ++ + + +K+F
Sbjct: 9412 KPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAE 9471
Query: 74 NKIERSILHDVV----EVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDP 129
K+ ++ V EV+ +S+ E+++ + ++++E +EE + +P
Sbjct: 9472 EKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEP 9531
Query: 130 QKAEEKRKLKELAQRQEEEAA-----QQGPVVVSP 159
++ + KL +++R E E A Q+ +V+ P
Sbjct: 9532 EEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKP 9566
>gi|21361137 nuclear transcription factor, X-box binding 1 isoform 1
[Homo sapiens]
Length = 1120
Score = 39.7 bits (91), Expect = 0.002
Identities = 21/76 (27%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
Query: 28 REQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQ--DSGQIKKK---FQPMNKIERSILH 82
R ++ +++ ++ ++F +EKE+ ++ + G+ KK F PMN+ R I+H
Sbjct: 976 RSSGSKFSDSLKEDARKDLKFVSDVEKEMETLVEAVNKGKNSKKSHSFPPMNRDHRRIIH 1035
Query: 83 DVVEVAGLTSFSFGED 98
D+ +V GL S S+ +
Sbjct: 1036 DLAQVYGLESVSYDSE 1051
>gi|38261971 cyclic AMP-regulated phosphoprotein, 21 kD isoform 1
[Homo sapiens]
Length = 812
Score = 37.7 bits (86), Expect = 0.008
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 7/87 (8%)
Query: 51 RMEKEVSDFIQDSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKE 110
+ME+E+ DFI D+ KKF M+ +R ++H V GL D + V+I K
Sbjct: 169 KMEQEIIDFIADNNNHYKKFPQMSSYQRMLVHRVAAYFGL---DHNVDQTGKSVIINK-- 223
Query: 111 FAPSDEELDSYRRGEEWDPQKAEEKRK 137
S + R E +K EE +K
Sbjct: 224 --TSSTRIPEQRFCEHLKDEKGEESQK 248
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 37.4 bits (85), Expect = 0.011
Identities = 30/135 (22%), Positives = 65/135 (48%), Gaps = 22/135 (16%)
Query: 64 GQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKE-FAPSDEELDSYR 122
G ++ +F P+ K+ ++L V G+ FG++D + + + + E F +EE D
Sbjct: 1832 GSVEFQFVPVLKLVSTLL-----VMGI----FGDEDVKQILKMIEPEVFTEEEEEEDEEE 1882
Query: 123 RGEEWDPQ------------KAEEKRKLKELAQRQEEEAAQQGPVVVSPASDYKDKYSHL 170
GEE D + K +E+++ +E A+ ++EE ++G + + K + HL
Sbjct: 1883 EGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGLLQMKLPESVKLQMCHL 1942
Query: 171 IGKGAAKDAAHMLQA 185
+ ++ H +++
Sbjct: 1943 LEYFCDQELQHRVES 1957
>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
sapiens]
Length = 5038
Score = 37.4 bits (85), Expect = 0.011
Identities = 30/135 (22%), Positives = 65/135 (48%), Gaps = 22/135 (16%)
Query: 64 GQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKE-FAPSDEELDSYR 122
G ++ +F P+ K+ ++L V G+ FG++D + + + + E F +EE D
Sbjct: 1832 GSVEFQFVPVLKLVSTLL-----VMGI----FGDEDVKQILKMIEPEVFTEEEEEEDEEE 1882
Query: 123 RGEEWDPQ------------KAEEKRKLKELAQRQEEEAAQQGPVVVSPASDYKDKYSHL 170
GEE D + K +E+++ +E A+ ++EE ++G + + K + HL
Sbjct: 1883 EGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGLLQMKLPESVKLQMCHL 1942
Query: 171 IGKGAAKDAAHMLQA 185
+ ++ H +++
Sbjct: 1943 LEYFCDQELQHRVES 1957
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 36.6 bits (83), Expect = 0.018
Identities = 36/146 (24%), Positives = 72/146 (49%), Gaps = 25/146 (17%)
Query: 9 LSSMEKPPSLGDQETRRKAREQAARL---KKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQ 65
L +EK + ++ RR+A +A R +K QE+ ++Q+ E +R ++E ++
Sbjct: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 779
Query: 66 IKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGE 125
++K + + +R E+A + ++E ++ ++ RR E
Sbjct: 780 ARRKQEEALRRQRE-----QEIA----------------LRRQREEEERQQQEEALRRLE 818
Query: 126 EWDPQKAEEKRKLKELAQRQEEEAAQ 151
E ++ EE+RK +EL ++QEEEAA+
Sbjct: 819 E-RRREEEERRKQEELLRKQEEEAAK 843
Score = 33.5 bits (75), Expect = 0.15
Identities = 23/128 (17%), Positives = 65/128 (50%), Gaps = 7/128 (5%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERSI 80
+E R + E+AARL+ +E+ K++++E ++ +KE+ Q + ++ Q + ++
Sbjct: 856 EENRLRMEEEAARLRHEEEERKRKELEVQR--QKELMRQRQQQQEALRRLQQQQQQQQ-- 911
Query: 81 LHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRKLKE 140
+ ++ +S ++G+ + ++L+ R + + Q+ +++ +K
Sbjct: 912 ---LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKA 968
Query: 141 LAQRQEEE 148
L Q+Q+++
Sbjct: 969 LQQQQQQQ 976
Score = 30.0 bits (66), Expect = 1.7
Identities = 15/49 (30%), Positives = 29/49 (59%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKK 69
+E RK E+AA+ + +E+ +++ E R RME+E + + + K+K
Sbjct: 831 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 879
Score = 28.1 bits (61), Expect = 6.4
Identities = 37/177 (20%), Positives = 74/177 (41%), Gaps = 37/177 (20%)
Query: 2 ADLLGSILSSMEKPPS-----------LGDQETRRKAREQAARLKKLQEQEKQQKVEFRK 50
+DL+ SI S+ + S +G + + K + A+ K + +Q K
Sbjct: 1053 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKK---- 1108
Query: 51 RMEKEVSDFIQDSGQIKKKFQPMNKIE-------RSILHDVVEVAGL---TSFSFGEDDD 100
+++ ++ K FQ +NK + +LH + L T SF ++ +
Sbjct: 1109 ---------VEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVE 1159
Query: 101 CRY-VMIFKKEFAPSDEELDSYRRG--EEWDPQKAEEKRKLKELAQRQEEEAAQQGP 154
Y V + + + E + + E QKA ++R+ ++L Q+Q+++ QQ P
Sbjct: 1160 SPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPP 1216
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 36.6 bits (83), Expect = 0.018
Identities = 36/146 (24%), Positives = 72/146 (49%), Gaps = 25/146 (17%)
Query: 9 LSSMEKPPSLGDQETRRKAREQAARL---KKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQ 65
L +EK + ++ RR+A +A R +K QE+ ++Q+ E +R ++E ++
Sbjct: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 806
Query: 66 IKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGE 125
++K + + +R E+A + ++E ++ ++ RR E
Sbjct: 807 ARRKQEEALRRQRE-----QEIA----------------LRRQREEEERQQQEEALRRLE 845
Query: 126 EWDPQKAEEKRKLKELAQRQEEEAAQ 151
E ++ EE+RK +EL ++QEEEAA+
Sbjct: 846 E-RRREEEERRKQEELLRKQEEEAAK 870
Score = 33.5 bits (75), Expect = 0.15
Identities = 23/128 (17%), Positives = 65/128 (50%), Gaps = 7/128 (5%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERSI 80
+E R + E+AARL+ +E+ K++++E ++ +KE+ Q + ++ Q + ++
Sbjct: 883 EENRLRMEEEAARLRHEEEERKRKELEVQR--QKELMRQRQQQQEALRRLQQQQQQQQ-- 938
Query: 81 LHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRKLKE 140
+ ++ +S ++G+ + ++L+ R + + Q+ +++ +K
Sbjct: 939 ---LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKA 995
Query: 141 LAQRQEEE 148
L Q+Q+++
Sbjct: 996 LQQQQQQQ 1003
Score = 30.0 bits (66), Expect = 1.7
Identities = 15/49 (30%), Positives = 29/49 (59%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKK 69
+E RK E+AA+ + +E+ +++ E R RME+E + + + K+K
Sbjct: 858 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 906
Score = 28.1 bits (61), Expect = 6.4
Identities = 37/177 (20%), Positives = 74/177 (41%), Gaps = 37/177 (20%)
Query: 2 ADLLGSILSSMEKPPS-----------LGDQETRRKAREQAARLKKLQEQEKQQKVEFRK 50
+DL+ SI S+ + S +G + + K + A+ K + +Q K
Sbjct: 1080 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKK---- 1135
Query: 51 RMEKEVSDFIQDSGQIKKKFQPMNKIE-------RSILHDVVEVAGL---TSFSFGEDDD 100
+++ ++ K FQ +NK + +LH + L T SF ++ +
Sbjct: 1136 ---------VEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVE 1186
Query: 101 CRY-VMIFKKEFAPSDEELDSYRRG--EEWDPQKAEEKRKLKELAQRQEEEAAQQGP 154
Y V + + + E + + E QKA ++R+ ++L Q+Q+++ QQ P
Sbjct: 1187 SPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPP 1243
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 36.6 bits (83), Expect = 0.018
Identities = 36/146 (24%), Positives = 72/146 (49%), Gaps = 25/146 (17%)
Query: 9 LSSMEKPPSLGDQETRRKAREQAARL---KKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQ 65
L +EK + ++ RR+A +A R +K QE+ ++Q+ E +R ++E ++
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785
Query: 66 IKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGE 125
++K + + +R E+A + ++E ++ ++ RR E
Sbjct: 786 ARRKQEEALRRQRE-----QEIA----------------LRRQREEEERQQQEEALRRLE 824
Query: 126 EWDPQKAEEKRKLKELAQRQEEEAAQ 151
E ++ EE+RK +EL ++QEEEAA+
Sbjct: 825 E-RRREEEERRKQEELLRKQEEEAAK 849
Score = 33.5 bits (75), Expect = 0.15
Identities = 23/128 (17%), Positives = 65/128 (50%), Gaps = 7/128 (5%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERSI 80
+E R + E+AARL+ +E+ K++++E ++ +KE+ Q + ++ Q + ++
Sbjct: 862 EENRLRMEEEAARLRHEEEERKRKELEVQR--QKELMRQRQQQQEALRRLQQQQQQQQ-- 917
Query: 81 LHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRKLKE 140
+ ++ +S ++G+ + ++L+ R + + Q+ +++ +K
Sbjct: 918 ---LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKA 974
Query: 141 LAQRQEEE 148
L Q+Q+++
Sbjct: 975 LQQQQQQQ 982
Score = 30.0 bits (66), Expect = 1.7
Identities = 15/49 (30%), Positives = 29/49 (59%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKK 69
+E RK E+AA+ + +E+ +++ E R RME+E + + + K+K
Sbjct: 837 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 885
Score = 28.1 bits (61), Expect = 6.4
Identities = 37/177 (20%), Positives = 74/177 (41%), Gaps = 37/177 (20%)
Query: 2 ADLLGSILSSMEKPPS-----------LGDQETRRKAREQAARLKKLQEQEKQQKVEFRK 50
+DL+ SI S+ + S +G + + K + A+ K + +Q K
Sbjct: 1059 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKK---- 1114
Query: 51 RMEKEVSDFIQDSGQIKKKFQPMNKIE-------RSILHDVVEVAGL---TSFSFGEDDD 100
+++ ++ K FQ +NK + +LH + L T SF ++ +
Sbjct: 1115 ---------VEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVE 1165
Query: 101 CRY-VMIFKKEFAPSDEELDSYRRG--EEWDPQKAEEKRKLKELAQRQEEEAAQQGP 154
Y V + + + E + + E QKA ++R+ ++L Q+Q+++ QQ P
Sbjct: 1166 SPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPP 1222
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 36.6 bits (83), Expect = 0.018
Identities = 36/146 (24%), Positives = 72/146 (49%), Gaps = 25/146 (17%)
Query: 9 LSSMEKPPSLGDQETRRKAREQAARL---KKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQ 65
L +EK + ++ RR+A +A R +K QE+ ++Q+ E +R ++E ++
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785
Query: 66 IKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGE 125
++K + + +R E+A + ++E ++ ++ RR E
Sbjct: 786 ARRKQEEALRRQRE-----QEIA----------------LRRQREEEERQQQEEALRRLE 824
Query: 126 EWDPQKAEEKRKLKELAQRQEEEAAQ 151
E ++ EE+RK +EL ++QEEEAA+
Sbjct: 825 E-RRREEEERRKQEELLRKQEEEAAK 849
Score = 33.5 bits (75), Expect = 0.15
Identities = 23/128 (17%), Positives = 65/128 (50%), Gaps = 7/128 (5%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERSI 80
+E R + E+AARL+ +E+ K++++E ++ +KE+ Q + ++ Q + ++
Sbjct: 862 EENRLRMEEEAARLRHEEEERKRKELEVQR--QKELMRQRQQQQEALRRLQQQQQQQQ-- 917
Query: 81 LHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRKLKE 140
+ ++ +S ++G+ + ++L+ R + + Q+ +++ +K
Sbjct: 918 ---LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKA 974
Query: 141 LAQRQEEE 148
L Q+Q+++
Sbjct: 975 LQQQQQQQ 982
Score = 30.0 bits (66), Expect = 1.7
Identities = 15/49 (30%), Positives = 29/49 (59%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKK 69
+E RK E+AA+ + +E+ +++ E R RME+E + + + K+K
Sbjct: 837 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 885
Score = 28.1 bits (61), Expect = 6.4
Identities = 37/177 (20%), Positives = 74/177 (41%), Gaps = 37/177 (20%)
Query: 2 ADLLGSILSSMEKPPS-----------LGDQETRRKAREQAARLKKLQEQEKQQKVEFRK 50
+DL+ SI S+ + S +G + + K + A+ K + +Q K
Sbjct: 1059 SDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKK---- 1114
Query: 51 RMEKEVSDFIQDSGQIKKKFQPMNKIE-------RSILHDVVEVAGL---TSFSFGEDDD 100
+++ ++ K FQ +NK + +LH + L T SF ++ +
Sbjct: 1115 ---------VEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVE 1165
Query: 101 CRY-VMIFKKEFAPSDEELDSYRRG--EEWDPQKAEEKRKLKELAQRQEEEAAQQGP 154
Y V + + + E + + E QKA ++R+ ++L Q+Q+++ QQ P
Sbjct: 1166 SPYEVHDYIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQPP 1222
>gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]
Length = 1069
Score = 36.6 bits (83), Expect = 0.018
Identities = 38/163 (23%), Positives = 64/163 (39%), Gaps = 21/163 (12%)
Query: 12 MEKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKF- 70
M K + +E +R+ E++A+LK++ +E + K+ + D+ Q Q+ ++
Sbjct: 890 MTKQKLIDAEEEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLE 949
Query: 71 --QPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEE-W 127
Q NK+E + V DDC +EF + + +E
Sbjct: 950 KQQTANKVEIEKIRQKV-------------DDCERC----REFFNKEGRVKGISSTKEVL 992
Query: 128 DPQKAEEKRKLKELAQRQEEEAAQQGPVVVSPASDYKDKYSHL 170
D EEK LK + E E AQ +V +D HL
Sbjct: 993 DEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHL 1035
Score = 32.0 bits (71), Expect = 0.45
Identities = 38/195 (19%), Positives = 81/195 (41%), Gaps = 37/195 (18%)
Query: 12 MEKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVS--DFIQDSGQIKKK 69
++ P +E +K E A +K Q++ K+ + E+ E++ D I+ + ++
Sbjct: 785 VQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRR 844
Query: 70 FQPMN-KIERSILHDVVEVAGLTSFSFGEDDDCRYVMI-----FKKEFAPSDEELDSYRR 123
Q N ++E+ E+DD + ++ +K+ ++E+ D+ +
Sbjct: 845 LQEANMRLEQ------------------ENDDLAHELVTSKIALRKDLDNAEEKADALNK 886
Query: 124 -----------GEEWDPQKAEEKRKLKELAQRQEEEAAQQGPVVVSPASDYKDKYSHLIG 172
EE + EE +LKE+ +R+ ++A + S DYK S L
Sbjct: 887 ELLMTKQKLIDAEEEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSE 946
Query: 173 KGAAKDAAHMLQANK 187
+ + A+ ++ K
Sbjct: 947 RLEKQQTANKVEIEK 961
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 36.2 bits (82), Expect = 0.024
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 30/141 (21%)
Query: 7 SILSSMEKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQI 66
S+L +EK SL +E + E+ ++++E+E+++K E + EK+V ++ +
Sbjct: 2232 SLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEE-EEGEEKQVE---KEEEEK 2287
Query: 67 KKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEE 126
KKK + K E +V E +KE S+EE +S
Sbjct: 2288 KKKKKEKKKEEVQEKEEVFE---------------------EKEEIMSEEETESLS---- 2322
Query: 127 WDPQKAEEKRKLKELAQRQEE 147
D ++ EE L+E R++E
Sbjct: 2323 -DEEEEEESCSLEEEVDREKE 2342
Score = 29.6 bits (65), Expect = 2.2
Identities = 30/150 (20%), Positives = 67/150 (44%), Gaps = 19/150 (12%)
Query: 20 DQETRRKAREQAARLKKLQEQEKQQKVEFRKRM-----------------EKEVSDFIQD 62
+++ RK R+ A +++++ +E++ E K E+EV F++
Sbjct: 2136 EKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKR 2195
Query: 63 SGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYR 122
+ +K+ + +K + V EV FS E+ + + K+E S+EE +
Sbjct: 2196 RWRKRKEAKRGDKPKEKFSSQVDEVESEEHFS--EEMESLLDELEKQESLSSEEEEEREE 2253
Query: 123 RGEEWDPQKAEEKRKLKELAQRQEEEAAQQ 152
E + + EE+ + KE + +E++ ++
Sbjct: 2254 EEEREEEEVREEEEERKEEEEGEEKQVEKE 2283
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 35.8 bits (81), Expect = 0.031
Identities = 49/224 (21%), Positives = 97/224 (43%), Gaps = 50/224 (22%)
Query: 21 QETRRKAREQAARLKKLQEQ----------EKQQKVEFRKRMEKEVSDFIQDSGQIKKKF 70
+E RR+ EQ R K+L++Q E+ ++ E R+R E E ++I+ Q++++
Sbjct: 399 KEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHE-QEYIR--RQLEEEQ 455
Query: 71 QPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQ 130
+ + +++ +LH+ ++ +K+ ++L+ R+ E Q
Sbjct: 456 RQLEILQQQLLHEQA-----------------LLLEYKR------KQLEEQRQAERLQRQ 492
Query: 131 KAEEKRKLKELAQRQEEEAAQQGPVVVSPASDYKDKYSHLIGKGAAKDAAHMLQANKTYG 190
+E+ L L +++E Q PV P YK+ S AK+ H++ A K+ G
Sbjct: 493 LKQERDYLVSLQHQRQE----QRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLV-AVKSQG 547
Query: 191 CVPVANK-------RDTRSIEEAMNEIRAKKRLRQSGEELPPTS 227
A++ + +EA+N R+ + PTS
Sbjct: 548 PALTASQSVHEQPTKGLSGFQEALNV--TSHRVEMPRQNSDPTS 589
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 35.8 bits (81), Expect = 0.031
Identities = 49/224 (21%), Positives = 97/224 (43%), Gaps = 50/224 (22%)
Query: 21 QETRRKAREQAARLKKLQEQ----------EKQQKVEFRKRMEKEVSDFIQDSGQIKKKF 70
+E RR+ EQ R K+L++Q E+ ++ E R+R E E ++I+ Q++++
Sbjct: 399 KEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHE-QEYIR--RQLEEEQ 455
Query: 71 QPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQ 130
+ + +++ +LH+ ++ +K+ ++L+ R+ E Q
Sbjct: 456 RQLEILQQQLLHEQA-----------------LLLEYKR------KQLEEQRQAERLQRQ 492
Query: 131 KAEEKRKLKELAQRQEEEAAQQGPVVVSPASDYKDKYSHLIGKGAAKDAAHMLQANKTYG 190
+E+ L L +++E Q PV P YK+ S AK+ H++ A K+ G
Sbjct: 493 LKQERDYLVSLQHQRQE----QRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLV-AVKSQG 547
Query: 191 CVPVANK-------RDTRSIEEAMNEIRAKKRLRQSGEELPPTS 227
A++ + +EA+N R+ + PTS
Sbjct: 548 PALTASQSVHEQPTKGLSGFQEALNV--TSHRVEMPRQNSDPTS 589
>gi|31543535 R3H domain containing 1 [Homo sapiens]
Length = 1099
Score = 35.8 bits (81), Expect = 0.031
Identities = 16/40 (40%), Positives = 24/40 (60%)
Query: 51 RMEKEVSDFIQDSGQIKKKFQPMNKIERSILHDVVEVAGL 90
++E+E+ DFI ++ +KKF PM R +LH V GL
Sbjct: 173 KLEQEILDFIGNNESPRKKFPPMTSYHRMLLHRVAAYFGL 212
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 35.8 bits (81), Expect = 0.031
Identities = 39/157 (24%), Positives = 72/157 (45%), Gaps = 18/157 (11%)
Query: 7 SILSSMEK--PPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSG 64
S++ S K P D + + + R + R K+ EQ ++QKVE KR E ++
Sbjct: 514 SVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE- 572
Query: 65 QIKKKFQPMNKIE-------RSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEE 117
+++K Q ++E + I ++ T + +++ KK A EE
Sbjct: 573 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKA--KEERLAEEKAKKKAAAKKMEE 630
Query: 118 LDSYRRGEE------WDPQKAEEKRKLKELAQRQEEE 148
+++ R+ EE W Q+ EE+R + L +++EEE
Sbjct: 631 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEE 667
Score = 31.6 bits (70), Expect = 0.58
Identities = 27/132 (20%), Positives = 61/132 (46%), Gaps = 15/132 (11%)
Query: 22 ETRRKAREQAARLKKLQEQEKQQK-VEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERSI 80
E RRK E+A RL+ LQ++E++++ E ++ ++E + ++ + + K+ + + R
Sbjct: 632 EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE- 690
Query: 81 LHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRKLKE 140
+ + R ++E + +L R E + +AE + + +E
Sbjct: 691 -------------QERREQERREQERREQERREQERQLAEQERRREQERLQAERELQERE 737
Query: 141 LAQRQEEEAAQQ 152
A R ++E Q+
Sbjct: 738 KALRLQKEQLQR 749
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 35.4 bits (80), Expect = 0.040
Identities = 34/139 (24%), Positives = 62/139 (44%), Gaps = 26/139 (18%)
Query: 10 SSMEKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKK 69
SS EK D+E ++ KL+E+ +++K K E++ +++ G++KK+
Sbjct: 129 SSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKE 188
Query: 70 FQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELD-SYRRGEEWD 128
+ M + ++ L D +DDD E P++ E + + GEE D
Sbjct: 189 IEEMKQGKKWSLED-------------DDDD---------EDDPAEAEKEGNEMEGEELD 226
Query: 129 PQKA---EEKRKLKELAQR 144
P A E K ++K+ R
Sbjct: 227 PLDAYMEEVKEEVKKFNMR 245
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 35.4 bits (80), Expect = 0.040
Identities = 30/135 (22%), Positives = 63/135 (46%), Gaps = 13/135 (9%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKK-KFQPMNKIERS 79
+ RRK + R +K++E ++++ E + + E+ + +Q ++++ K + +IE+
Sbjct: 543 ENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQK 602
Query: 80 ILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEE------WDPQKAE 133
+ E+ KK A EE+++ R+ EE W Q+ E
Sbjct: 603 FAQIDEKTEKAKEERLAEEK------AKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE 656
Query: 134 EKRKLKELAQRQEEE 148
E+R + L +++EEE
Sbjct: 657 ERRHQELLQKKKEEE 671
Score = 31.6 bits (70), Expect = 0.58
Identities = 27/132 (20%), Positives = 61/132 (46%), Gaps = 15/132 (11%)
Query: 22 ETRRKAREQAARLKKLQEQEKQQK-VEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERSI 80
E RRK E+A RL+ LQ++E++++ E ++ ++E + ++ + + K+ + + R
Sbjct: 636 EARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE- 694
Query: 81 LHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRKLKE 140
+ + R ++E + +L R E + +AE + + +E
Sbjct: 695 -------------QERREQERREQERREQERREQERQLAEQERRREQERLQAERELQERE 741
Query: 141 LAQRQEEEAAQQ 152
A R ++E Q+
Sbjct: 742 KALRLQKEQLQR 753
>gi|7656983 TP53-target gene 5 protein [Homo sapiens]
Length = 290
Score = 35.0 bits (79), Expect = 0.053
Identities = 28/122 (22%), Positives = 59/122 (48%), Gaps = 12/122 (9%)
Query: 26 KAREQAARLKKLQEQEKQQKVE--FRKRMEKE-VSDFIQDSGQIK------KKFQPMNKI 76
K R + +R+ K+Q+++ + + E K +E+ + +++ +K ++ Q ++K+
Sbjct: 6 KKRPKNSRVSKMQDEKLRDETEQPVSKVIERNRLRTVLKNLSLLKLLKSSNRRIQELHKL 65
Query: 77 ERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAP---SDEELDSYRRGEEWDPQKAE 133
+ H ++ V + S GE+ C +EF S++EL S + DP+K E
Sbjct: 66 AKRCWHSLLSVPKILRISSGENSACNKTKQNNEEFQEIGCSEKELKSKKLESTGDPKKKE 125
Query: 134 EK 135
K
Sbjct: 126 YK 127
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 34.7 bits (78), Expect = 0.069
Identities = 28/145 (19%), Positives = 68/145 (46%), Gaps = 5/145 (3%)
Query: 13 EKPPSLGDQETR-----RKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIK 67
E+ + +QE + K REQ ++++ +E+ +Q+ + R++ EK + +++
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Query: 68 KKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEW 127
++ + + + E + ++ L +++ R V +E +E + + +E
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEE 476
Query: 128 DPQKAEEKRKLKELAQRQEEEAAQQ 152
Q+ EEK +E +QEE+ +Q
Sbjct: 477 KIQEQEEKTWRQEKLLKQEEKIWEQ 501
Score = 33.5 bits (75), Expect = 0.15
Identities = 30/140 (21%), Positives = 71/140 (50%), Gaps = 9/140 (6%)
Query: 20 DQETRRKAR--EQAARLKKLQEQEKQQKVEFRKRMEK--EVSDFIQDSGQIKKKFQPMNK 75
+QE +R+ + Q ++++ E+ ++Q+ E ++ EK E+ + +QD + ++ + +
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Query: 76 IERSILHDVVEVAGLTSFSFGEDDD--CRYVMIFKKEFAPSDEELDSYRRGEE-WDPQKA 132
E + + E E ++ R + K+E ++E +R+ E+ W+ +
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE-- 516
Query: 133 EEKRKLKELAQRQEEEAAQQ 152
E+ ++ +E QRQEE+ +Q
Sbjct: 517 EKMQEQEEKMQRQEEKMREQ 536
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 34.7 bits (78), Expect = 0.069
Identities = 28/145 (19%), Positives = 68/145 (46%), Gaps = 5/145 (3%)
Query: 13 EKPPSLGDQETR-----RKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIK 67
E+ + +QE + K REQ ++++ +E+ +Q+ + R++ EK + +++
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Query: 68 KKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEW 127
++ + + + E + ++ L +++ R V +E +E + + +E
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEE 476
Query: 128 DPQKAEEKRKLKELAQRQEEEAAQQ 152
Q+ EEK +E +QEE+ +Q
Sbjct: 477 KIQEQEEKTWRQEKLLKQEEKIWEQ 501
Score = 33.5 bits (75), Expect = 0.15
Identities = 30/140 (21%), Positives = 71/140 (50%), Gaps = 9/140 (6%)
Query: 20 DQETRRKAR--EQAARLKKLQEQEKQQKVEFRKRMEK--EVSDFIQDSGQIKKKFQPMNK 75
+QE +R+ + Q ++++ E+ ++Q+ E ++ EK E+ + +QD + ++ + +
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Query: 76 IERSILHDVVEVAGLTSFSFGEDDD--CRYVMIFKKEFAPSDEELDSYRRGEE-WDPQKA 132
E + + E E ++ R + K+E ++E +R+ E+ W+ +
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE-- 516
Query: 133 EEKRKLKELAQRQEEEAAQQ 152
E+ ++ +E QRQEE+ +Q
Sbjct: 517 EKMQEQEEKMQRQEEKMREQ 536
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 34.7 bits (78), Expect = 0.069
Identities = 29/128 (22%), Positives = 64/128 (50%), Gaps = 5/128 (3%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERSI 80
++ RR+ RE+ L+ L+E+E+ Q+ E +++++E +D + + + Q ++ R
Sbjct: 818 EQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQ 877
Query: 81 LHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRKLKE 140
L + + T ++ + +KE EE + +R E ++ E++R+ +E
Sbjct: 878 LEEERKRRRHTLYAKPALQE-----QLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE 932
Query: 141 LAQRQEEE 148
Q Q+EE
Sbjct: 933 EEQLQQEE 940
Score = 34.7 bits (78), Expect = 0.069
Identities = 34/148 (22%), Positives = 70/148 (47%), Gaps = 10/148 (6%)
Query: 12 MEKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQ 71
+++ L QE RK RE+ ++ ++++ +++ +RK +E+E ++ Q++++ +
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769
Query: 72 PMNKIERSILHDVVEVAGLTS----FSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEW 127
E L E L S F E++ R ++E ++ D R EE
Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE---REEQQLRPQQRDGKYRWEEE 1826
Query: 128 DPQKAEEKRKLKELAQRQ---EEEAAQQ 152
Q E++++L++ RQ EE+ A Q
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQ 1854
Score = 34.3 bits (77), Expect = 0.090
Identities = 30/136 (22%), Positives = 67/136 (49%), Gaps = 9/136 (6%)
Query: 19 GDQETRRKAREQAARLKKLQEQEKQQKVE--FRKRMEKEVSDFIQDSGQIKKKFQPMNKI 76
G +E +++ RE+ R+ + +E+++ +K E RK EK + Q +++++ + + K+
Sbjct: 222 GREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL 281
Query: 77 ERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKR 136
ER L + + R +K+ E+ + R E+ + ++ +E+R
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLR-----RKQEEERREQQE--ERREQQERREQQEER 334
Query: 137 KLKELAQRQEEEAAQQ 152
+ ++L + QEE QQ
Sbjct: 335 REQQLRREQEERREQQ 350
Score = 33.9 bits (76), Expect = 0.12
Identities = 28/132 (21%), Positives = 62/132 (46%), Gaps = 17/132 (12%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERSI 80
QE RK RE+ L++ +EQ+ ++ RK F+++ Q++++ + E+ +
Sbjct: 1457 QERHRKFREEEQLLQEREEQQLHRQERDRK--------FLEEEQQLRRQERDRKFREQEL 1508
Query: 81 LHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRKLKE 140
E F E++ + +++F +++L RG++ ++ + RK +E
Sbjct: 1509 RSQEPE------RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ---RRQDRDRKFRE 1559
Query: 141 LAQRQEEEAAQQ 152
Q ++E QQ
Sbjct: 1560 EEQLRQEREEQQ 1571
Score = 33.5 bits (75), Expect = 0.15
Identities = 38/205 (18%), Positives = 89/205 (43%), Gaps = 9/205 (4%)
Query: 21 QETRRKAREQAARLKKLQEQ-EKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERS 79
Q R+K +EQ L + +EQ EKQ+++E R R ++ ++ + ++++Q + R+
Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRD-----EELWRQRQEWQEREE-RRA 188
Query: 80 ILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEK--RK 137
+ G + F +++ R + + +E+ R ++ Q+ EEK RK
Sbjct: 189 EEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRK 248
Query: 138 LKELAQRQEEEAAQQGPVVVSPASDYKDKYSHLIGKGAAKDAAHMLQANKTYGCVPVANK 197
+ + +++EE+ ++ P + +++ L + ++ Q + +
Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308
Query: 198 RDTRSIEEAMNEIRAKKRLRQSGEE 222
+ E E R ++ R+ EE
Sbjct: 309 KQEEERREQQEERREQQERREQQEE 333
Score = 33.1 bits (74), Expect = 0.20
Identities = 42/213 (19%), Positives = 90/213 (42%), Gaps = 29/213 (13%)
Query: 14 KPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVS-DFIQDSGQI--KKKF 70
+PP +E + +A E+ R ++ +E++++ R+R E+E F+++ Q+ +++
Sbjct: 787 RPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERA 846
Query: 71 QPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQ 130
Q + + E + D S D R+ + +EE R P
Sbjct: 847 QQLQEEEDGLQEDQER---RRSQEQRRDQKWRWQL---------EEERKRRRHTLYAKPA 894
Query: 131 KAEEKRKLKELAQRQEEEAAQQGPVVVSPASDYKDKYSHLIGKGAAKDAAHMLQANKTYG 190
E+ RK ++L Q +EEE + + ++K + ++ + Q +
Sbjct: 895 LQEQLRKEQQLLQEEEEELQR----------EEREKRRRQEQERQYREEEQLQQEEEQL- 943
Query: 191 CVPVANKRDTRSIEEAMNEIRAKKRLRQSGEEL 223
+ +R+ R +E + R K+L+Q E+L
Sbjct: 944 ---LREEREKRRRQERERQYRKDKKLQQKEEQL 973
Score = 32.0 bits (71), Expect = 0.45
Identities = 30/132 (22%), Positives = 61/132 (46%), Gaps = 11/132 (8%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERSI 80
+E + E+ R ++LQE+E+Q + R+ + +E + Q +++++ Q K E
Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 81 LHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRKLKE 140
E E + R ++E E+ + R E+ ++ EE+R+ ++
Sbjct: 315 REQQEERR--------EQQERREQQEERREQQLRREQEE---RREQQLRREQEEERREQQ 363
Query: 141 LAQRQEEEAAQQ 152
L + QEEE +Q
Sbjct: 364 LRREQEEERREQ 375
Score = 32.0 bits (71), Expect = 0.45
Identities = 33/135 (24%), Positives = 65/135 (48%), Gaps = 15/135 (11%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEV------SDFIQDSGQIKKKFQPMN 74
QET RK RE+ L++ +EQ +++ RK E+E+ F+++ +++++
Sbjct: 1332 QETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQ----- 1386
Query: 75 KIERSILHDVVEV-AGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAE 133
+ ER L + ++ +D D ++ ++E S +E D R EE ++ E
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKF---REEEQQLSRQERDRKFREEEQQVRRQE 1443
Query: 134 EKRKLKELAQRQEEE 148
+RK E Q+ +E
Sbjct: 1444 RERKFLEEEQQLRQE 1458
Score = 30.4 bits (67), Expect = 1.3
Identities = 45/217 (20%), Positives = 84/217 (38%), Gaps = 52/217 (23%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERSI 80
+E R K R Q + +E++ QQ+ E R E+E + Q +K + K E+ +
Sbjct: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL 974
Query: 81 LHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDE----------ELDSYRRGEEWDPQ 130
GE+ + R +K++ +E E RR +EW+ Q
Sbjct: 975 ---------------GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
Query: 131 --KAEEKRKLKELAQRQEEEAA--QQGPVVVSPASDYKDKYSHLIGKGAAKDAAHMLQAN 186
K +E ++ +E R+E E Q+ + + + L+G+
Sbjct: 1020 YRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE------------- 1066
Query: 187 KTYGCVPVANKRDTRSIEEAMNEIRAKKRLRQSGEEL 223
+R+TR +E + R ++ L+Q E+L
Sbjct: 1067 ----------ERETRRRQELERQYRKEEELQQEEEQL 1093
Score = 30.0 bits (66), Expect = 1.7
Identities = 28/140 (20%), Positives = 68/140 (48%), Gaps = 18/140 (12%)
Query: 20 DQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERS 79
+Q+ RR+ E+ R ++L+ QE++++++ R R E+++ ++ + K + ++E+
Sbjct: 504 EQQLRREQEER--REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQE 561
Query: 80 ILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFA-------PSDEELDSYRRGEEWDPQKA 132
++ E ++ R ++ ++E +E L+ + EE + +
Sbjct: 562 RREQRLK---------REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 133 EEKRKLKELAQRQEEEAAQQ 152
EE+R+ + + EEE QQ
Sbjct: 613 EERREQRLKREEPEEERRQQ 632
Score = 30.0 bits (66), Expect = 1.7
Identities = 32/137 (23%), Positives = 65/137 (47%), Gaps = 9/137 (6%)
Query: 18 LGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIE 77
LG++ +R+ +E+ + + +E+E QQ+ E R E+E + Q +KK + + E
Sbjct: 974 LGEEPEKRRRQEREKKYR--EEEELQQEEEQLLREEREKRRRQEWERQYRKK-DELQQEE 1030
Query: 78 RSILHDVVEVAGL--TSFSFGEDDDCR----YVMIFKKEFAPSDEELDSYRRGEEWDPQK 131
+L + E L + E+++ + ++ ++E E YR+ EE ++
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE 1090
Query: 132 AEEKRKLKELAQRQEEE 148
+ R+ E +RQE E
Sbjct: 1091 EQLLREEPEKRRRQERE 1107
Score = 29.6 bits (65), Expect = 2.2
Identities = 30/146 (20%), Positives = 68/146 (46%), Gaps = 11/146 (7%)
Query: 13 EKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRME-----KEVSDFIQDSGQIK 67
E+P QE +K RE+ L++ +EQ +++ E R+R E ++ + Q+ Q+
Sbjct: 976 EEPEKRRRQEREKKYREEE-ELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034
Query: 68 KKFQPMNKIE--RSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDE---ELDSYR 122
++ + +++ + E+ GE+ + R ++++ +E E +
Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094
Query: 123 RGEEWDPQKAEEKRKLKELAQRQEEE 148
R E ++ E +R+ +E + Q+EE
Sbjct: 1095 REEPEKRRRQERERQCREEEELQQEE 1120
Score = 29.6 bits (65), Expect = 2.2
Identities = 38/157 (24%), Positives = 61/157 (38%), Gaps = 31/157 (19%)
Query: 12 MEKPPSLGDQETR--------RKAREQAARLKKLQEQEKQQKVEFRKRMEKEVS------ 57
+E+ P L QE RK RE+ L++ +EQ+ +++ RK E+E
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
Query: 58 --DFIQDSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSD 115
F+Q+ Q++++ E L E L RY I ++E +
Sbjct: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQE-------RYRKILEEEQLRPE 1758
Query: 116 EELDSYRRGEEWDPQKAEEKRKLKELAQRQEEEAAQQ 152
E RR E RK +E Q ++E QQ
Sbjct: 1759 REEQQLRR--------QERDRKFREEEQLRQEREEQQ 1787
Score = 29.3 bits (64), Expect = 2.9
Identities = 34/148 (22%), Positives = 68/148 (45%), Gaps = 20/148 (13%)
Query: 9 LSSMEKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKK 68
L E+ Q+ RR+ +E+ R ++L+ +E+++++E R + E E Q+ + ++
Sbjct: 633 LLKSEEQEERRQQQLRREQQER--REQRLKREEEEERLEQRLKREHEEERREQELAE-EE 689
Query: 69 KFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIF----KKEFAPSDEELDSYRRG 124
+ Q +I+ I + + D R ++ K+E +E + RR
Sbjct: 690 QEQARERIKSRI--------PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRR 741
Query: 125 EEWDPQKAEEKRKLKELAQRQEEEAAQQ 152
E + Q EE+R A RQ++E Q+
Sbjct: 742 RESELQWQEEER-----AHRQQQEEEQR 764
Score = 28.9 bits (63), Expect = 3.8
Identities = 30/137 (21%), Positives = 68/137 (49%), Gaps = 9/137 (6%)
Query: 20 DQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQI---KKKFQPMNKI 76
+++ R+K Q + L+E+ ++++++ R+R +E + Q+ Q+ +++ + ++
Sbjct: 1017 ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL 1076
Query: 77 ERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKR 136
ER + E+ E+ + R ++E E + ++ EE ++ EKR
Sbjct: 1077 ERQYRKE-EELQQEEEQLLREEPEKRR----RQERERQCREEEELQQEEEQLLREEREKR 1131
Query: 137 KLKEL-AQRQEEEAAQQ 152
+ +EL Q +EEE QQ
Sbjct: 1132 RRQELERQYREEEEVQQ 1148
Score = 28.9 bits (63), Expect = 3.8
Identities = 46/211 (21%), Positives = 86/211 (40%), Gaps = 27/211 (12%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERSI 80
+E R K R Q + +E+E QQ+ E R E E + Q +++ + + E+ +
Sbjct: 1125 REEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL 1184
Query: 81 LHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRKLKE 140
+ + + E+++ + K+ + D+ D +W+P+K R K
Sbjct: 1185 REEQEKRRQERERQYREEEELQR-QKRKQRYRDEDQRSD---LKWQWEPEKENAVRDNKV 1240
Query: 141 LAQRQEEEAAQQGPVVVSPASDYKDKYS-----HLIGKGAAKDAAHMLQANKTYGCVPVA 195
+ +E E +Q S +D+ S HL+G+ +D Q + +
Sbjct: 1241 YCKGRENEQFRQ-----LEDSQLRDRQSQQDLQHLLGEQQERDRE---QERRRW------ 1286
Query: 196 NKRDTRSIEEAM----NEIRAKKRLRQSGEE 222
+RD EE + AK+R R+S EE
Sbjct: 1287 QQRDRHFPEEEQLEREEQKEAKRRDRKSQEE 1317
Score = 28.1 bits (61), Expect = 6.4
Identities = 27/146 (18%), Positives = 70/146 (47%), Gaps = 16/146 (10%)
Query: 20 DQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERS 79
+Q+ +R REQ R +K +E+ ++Q+ E R++ E+ + Q++++ + + E+
Sbjct: 294 EQQQQRLRREQQLR-RKQEEERREQQEERREQQERREQQEERREQQLRREQE--ERREQQ 350
Query: 80 ILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEEL---DSYRRGE----------E 126
+ + E ++++ R + +++ +++L RR + E
Sbjct: 351 LRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 410
Query: 127 WDPQKAEEKRKLKELAQRQEEEAAQQ 152
++ ++ R+ ++L + QEEE +Q
Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQ 436
Score = 27.7 bits (60), Expect = 8.4
Identities = 25/141 (17%), Positives = 63/141 (44%), Gaps = 26/141 (18%)
Query: 20 DQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFI---QDSGQIKKKFQPMNKI 76
DQE R+ R ++ +EQ+++++ + R+ E+ + ++ +++++ + ++
Sbjct: 479 DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 538
Query: 77 ERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQ-----K 131
R E ++ R ++ ++E ++E R E + + K
Sbjct: 539 RR------------------EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLK 580
Query: 132 AEEKRKLKELAQRQEEEAAQQ 152
EE+R+ + L + QEE Q+
Sbjct: 581 REEERRQQRLKREQEERLEQR 601
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 34.7 bits (78), Expect = 0.069
Identities = 45/222 (20%), Positives = 98/222 (44%), Gaps = 17/222 (7%)
Query: 6 GSILSSMEKPPSLGDQ-ETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSG 64
G++ + ++ L ++ + + +EQ RLK E E+ + ++++KE++D ++ S
Sbjct: 906 GNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASR 965
Query: 65 QIKKKFQ-PMNKIERSILHDVVEVAGLTSFSFGEDDDCRY-VMIFKKEFAPSDEELDSYR 122
+ Q +++ + ++ E+ E + R M + E +EEL Y+
Sbjct: 966 TSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQ 1025
Query: 123 RGEEWDPQKAEEKRKLKELAQRQEEEAAQQGPVVVSPASDYKDKYSHLIGKGAAKDAAHM 182
R ++ +A KR+L E + E + S KD S L+ + K +
Sbjct: 1026 RAQD----EALTKRQLLEQTLKDLE-------YELEAKSHLKDDRSRLVKQMEDKVSQLE 1074
Query: 183 LQANKTYGCVPVANKRDTRS---IEEAMNEIRAKKRLRQSGE 221
++ + + ++R +RS +E+ NE+ ++ RQ E
Sbjct: 1075 MELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLE 1116
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 34.3 bits (77), Expect = 0.090
Identities = 15/38 (39%), Positives = 27/38 (71%)
Query: 8 ILSSMEKPPSLGDQETRRKAREQAARLKKLQEQEKQQK 45
ILSS+ P GDQ+T KA ++A ++++ ++E+QQ+
Sbjct: 493 ILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQ 530
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 34.3 bits (77), Expect = 0.090
Identities = 15/38 (39%), Positives = 27/38 (71%)
Query: 8 ILSSMEKPPSLGDQETRRKAREQAARLKKLQEQEKQQK 45
ILSS+ P GDQ+T KA ++A ++++ ++E+QQ+
Sbjct: 453 ILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQ 490
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 34.3 bits (77), Expect = 0.090
Identities = 15/38 (39%), Positives = 27/38 (71%)
Query: 8 ILSSMEKPPSLGDQETRRKAREQAARLKKLQEQEKQQK 45
ILSS+ P GDQ+T KA ++A ++++ ++E+QQ+
Sbjct: 456 ILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQ 493
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 34.3 bits (77), Expect = 0.090
Identities = 15/38 (39%), Positives = 27/38 (71%)
Query: 8 ILSSMEKPPSLGDQETRRKAREQAARLKKLQEQEKQQK 45
ILSS+ P GDQ+T KA ++A ++++ ++E+QQ+
Sbjct: 480 ILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQ 517
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 34.3 bits (77), Expect = 0.090
Identities = 30/202 (14%), Positives = 89/202 (44%), Gaps = 11/202 (5%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKIERSI 80
+E + A + ++ LQ Q +K++ +++++ E ++ ++ +++ + + I
Sbjct: 858 REKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAE-TELCAEAEELRARLTAKKQELEEI 916
Query: 81 LHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRKLKE 140
HD L + E++ C+++ KK+ + +EL+ EE A +K +L++
Sbjct: 917 CHD------LEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE----SARQKLQLEK 966
Query: 141 LAQRQEEEAAQQGPVVVSPASDYKDKYSHLIGKGAAKDAAHMLQANKTYGCVPVANKRDT 200
+ + + ++ +++ + K L+ A+ ++ + + + +
Sbjct: 967 VTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHE 1026
Query: 201 RSIEEAMNEIRAKKRLRQSGEE 222
I + +R +++ RQ E+
Sbjct: 1027 AMITDLEERLRREEKQRQELEK 1048
Score = 28.1 bits (61), Expect = 6.4
Identities = 32/160 (20%), Positives = 65/160 (40%), Gaps = 10/160 (6%)
Query: 11 SMEKPPSLGDQETRRKAREQAARLK-KLQEQEKQQKVEFRKR---MEKEVSDFIQDSGQI 66
++E+ + ++ R++ Q LK KLQE E K +++ +E +++ +
Sbjct: 1767 NLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNE 1826
Query: 67 KKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEE 126
K+ Q K R + +V DD+ R +K + + L +R E
Sbjct: 1827 TKERQAACKQVRRTEKKLKDVL------LQVDDERRNAEQYKDQADKASTRLKQLKRQLE 1880
Query: 127 WDPQKAEEKRKLKELAQRQEEEAAQQGPVVVSPASDYKDK 166
++A+ + QR+ E+A + + S K+K
Sbjct: 1881 EAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNK 1920
Score = 27.7 bits (60), Expect = 8.4
Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 6/123 (4%)
Query: 21 QETRRKAREQAARLKKLQEQE----KQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNKI 76
QE R K ++ LKK E+E + Q E R++ + V + + Q K+ + K
Sbjct: 1159 QELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKA 1218
Query: 77 ERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKR 136
++++ ++ E+A D + KK A E + GE + A++
Sbjct: 1219 KQTLENERGELANEVKVLLQGKGDSEHKR--KKVEAQLQELQVKFNEGERVRTELADKVT 1276
Query: 137 KLK 139
KL+
Sbjct: 1277 KLQ 1279
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 34.3 bits (77), Expect = 0.090
Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 28/141 (19%)
Query: 13 EKPPSLGDQETRRKARE-----QAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIK 67
E+ ++E R++ RE + + +K E++K+++ ++R EKE G+ K
Sbjct: 58 ERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKE-----NKEGEEK 112
Query: 68 KKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEW 127
+K + K ER G TS E + +KE +E + R+ EE
Sbjct: 113 EKRKKKEKKER----------GRTSKEGKERE--------RKEERKREERKERERKKEER 154
Query: 128 DPQKAEEKRKLKELAQRQEEE 148
+ ++ ++RK +E Q E+E
Sbjct: 155 EKERERKERKKRERKQVGEKE 175
Score = 33.5 bits (75), Expect = 0.15
Identities = 26/140 (18%), Positives = 68/140 (48%), Gaps = 19/140 (13%)
Query: 13 EKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQP 72
EK G+++ +RK +E+ R + +E +++++ E RKR E++ + ++ + +++ +
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKE 162
Query: 73 MNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKA 132
K ER GE ++ R K++ ++ + R+ + + ++
Sbjct: 163 RKKRERK--------------QVGEKEEER-----KEKERKERKKRERNRKERKKERERK 203
Query: 133 EEKRKLKELAQRQEEEAAQQ 152
E + + KE +++E + +Q
Sbjct: 204 ERRERKKERKKKEERKKERQ 223
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 34.3 bits (77), Expect = 0.090
Identities = 27/135 (20%), Positives = 65/135 (48%), Gaps = 16/135 (11%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKR---MEKEVSDFIQDSGQIKKKFQPMNKIE 77
+E + REQ ++++ + Q ++Q+ + R++ + ++ + GQ++++ M + E
Sbjct: 139 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQE 198
Query: 78 RSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRK 137
+ G GE ++ +K+ E+ + R+ EE ++ E+ +K
Sbjct: 199 GQM--------GEQEEQMGEQEEQ-----MQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245
Query: 138 LKELAQRQEEEAAQQ 152
+E Q+QEE+ +Q
Sbjct: 246 QEEQVQKQEEQMRKQ 260
Score = 32.3 bits (72), Expect = 0.34
Identities = 30/143 (20%), Positives = 65/143 (45%), Gaps = 32/143 (22%)
Query: 13 EKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFR---KRMEKEVSDFIQDSGQIKKK 69
E+ G+QE + REQ ++++ +EQ ++Q+ + R ++M K+ + Q+ ++
Sbjct: 286 EQEEQTGEQE--EQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQ 343
Query: 70 FQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDP 129
+ M K E + GE ++ ++ + R+ EE
Sbjct: 344 KEQMWKQEEQM---------------GEQEE------------QMQKQEEQVRKQEEQMR 376
Query: 130 QKAEEKRKLKELAQRQEEEAAQQ 152
++ E+ RK +E ++QEE+ +Q
Sbjct: 377 KQEEQMRKQEEQMRKQEEQMGEQ 399
Score = 28.5 bits (62), Expect = 4.9
Identities = 27/140 (19%), Positives = 62/140 (44%), Gaps = 37/140 (26%)
Query: 18 LGDQETRRKARE-----QAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQP 72
+G+QE + + +E Q +++K +EQ ++Q+ + RK+ E Q++++ +
Sbjct: 222 MGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEE-----------QMREQEEQ 270
Query: 73 MNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKA 132
M + E +L + ++ + E+ + R EE ++
Sbjct: 271 MREQEEQMLKQKEQT---------------------EQEEQTGEQEEQMREQEEQMREQE 309
Query: 133 EEKRKLKELAQRQEEEAAQQ 152
E+ R+ +E + QEE+ +Q
Sbjct: 310 EQMREQEEQMREQEEQMGKQ 329
Score = 27.7 bits (60), Expect = 8.4
Identities = 12/51 (23%), Positives = 33/51 (64%), Gaps = 1/51 (1%)
Query: 21 QETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQ 71
Q+ + R+Q +++K +EQ ++Q+ + RK+ E+++ + + G+ K++ +
Sbjct: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ-EEQMGEQKEQMGEQKEQMR 411
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,624,162
Number of Sequences: 37866
Number of extensions: 388214
Number of successful extensions: 4970
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 234
Number of HSP's that attempted gapping in prelim test: 3549
Number of HSP's gapped (non-prelim): 1340
length of query: 227
length of database: 18,247,518
effective HSP length: 99
effective length of query: 128
effective length of database: 14,498,784
effective search space: 1855844352
effective search space used: 1855844352
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.