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Search of human proteins with 239751443
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239751443 PREDICTED: hypothetical protein [Homo sapiens]
(783 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239756943 PREDICTED: hypothetical protein [Homo sapiens] 1647 0.0
gi|239751443 PREDICTED: hypothetical protein [Homo sapiens] 1647 0.0
gi|239745948 PREDICTED: hypothetical protein XP_002343622 [Homo ... 1640 0.0
gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo sap... 45 3e-04
gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo sap... 45 3e-04
gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo sapi... 45 3e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 45 3e-04
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 42 0.002
gi|27894378 chloride intracellular channel 6 [Homo sapiens] 41 0.004
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 41 0.005
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 40 0.008
gi|156616290 collagen type VI alpha 6 [Homo sapiens] 40 0.011
gi|91208420 bassoon protein [Homo sapiens] 40 0.011
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 40 0.011
gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 40 0.011
gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens] 39 0.014
gi|160707881 formin 2 [Homo sapiens] 39 0.019
gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like ... 39 0.024
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 39 0.024
gi|169214011 PREDICTED: hypothetical protein [Homo sapiens] 38 0.032
gi|239756028 PREDICTED: hypothetical protein [Homo sapiens] 38 0.032
gi|113428768 PREDICTED: hypothetical protein [Homo sapiens] 38 0.032
gi|113428351 PREDICTED: hypothetical protein [Homo sapiens] 38 0.032
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 37 0.054
gi|122937233 discs, large (Drosophila) homolog-associated protei... 37 0.071
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 37 0.071
gi|4502081 amphiphysin isoform 1 [Homo sapiens] 37 0.092
gi|154146231 DMRT-like family A2 [Homo sapiens] 37 0.092
gi|60097902 filaggrin [Homo sapiens] 36 0.12
gi|239751449 PREDICTED: hypothetical protein XP_002347867 [Homo ... 36 0.12
>gi|239756943 PREDICTED: hypothetical protein [Homo sapiens]
Length = 783
Score = 1647 bits (4266), Expect = 0.0
Identities = 783/783 (100%), Positives = 783/783 (100%)
Query: 1 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH 60
MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH
Sbjct: 1 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH 60
Query: 61 QGHLSGLVHTGQQLPIVPALRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDGQPPALPVT 120
QGHLSGLVHTGQQLPIVPALRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDGQPPALPVT
Sbjct: 61 QGHLSGLVHTGQQLPIVPALRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDGQPPALPVT 120
Query: 121 TGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVALLWAGLGHL 180
TGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVALLWAGLGHL
Sbjct: 121 TGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVALLWAGLGHL 180
Query: 181 GDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDP 240
GDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDP
Sbjct: 181 GDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDP 240
Query: 241 MLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATA 300
MLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATA
Sbjct: 241 MLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATA 300
Query: 301 PNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKE 360
PNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKE
Sbjct: 301 PNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKE 360
Query: 361 EAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGD 420
EAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGD
Sbjct: 361 EAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGD 420
Query: 421 NARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDG 480
NARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDG
Sbjct: 421 NARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDG 480
Query: 481 HPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA 540
HPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA
Sbjct: 481 HPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA 540
Query: 541 GTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGANRAPAALQ 600
GTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGANRAPAALQ
Sbjct: 541 GTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGANRAPAALQ 600
Query: 601 VRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHAPACGRAHT 660
VRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHAPACGRAHT
Sbjct: 601 VRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHAPACGRAHT 660
Query: 661 HAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPHTEVRLLHA 720
HAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPHTEVRLLHA
Sbjct: 661 HAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPHTEVRLLHA 720
Query: 721 RSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGVGCAVLGAR 780
RSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGVGCAVLGAR
Sbjct: 721 RSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGVGCAVLGAR 780
Query: 781 SEA 783
SEA
Sbjct: 781 SEA 783
>gi|239751443 PREDICTED: hypothetical protein [Homo sapiens]
Length = 783
Score = 1647 bits (4266), Expect = 0.0
Identities = 783/783 (100%), Positives = 783/783 (100%)
Query: 1 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH 60
MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH
Sbjct: 1 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH 60
Query: 61 QGHLSGLVHTGQQLPIVPALRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDGQPPALPVT 120
QGHLSGLVHTGQQLPIVPALRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDGQPPALPVT
Sbjct: 61 QGHLSGLVHTGQQLPIVPALRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDGQPPALPVT 120
Query: 121 TGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVALLWAGLGHL 180
TGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVALLWAGLGHL
Sbjct: 121 TGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVALLWAGLGHL 180
Query: 181 GDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDP 240
GDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDP
Sbjct: 181 GDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDP 240
Query: 241 MLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATA 300
MLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATA
Sbjct: 241 MLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATA 300
Query: 301 PNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKE 360
PNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKE
Sbjct: 301 PNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKE 360
Query: 361 EAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGD 420
EAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGD
Sbjct: 361 EAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGD 420
Query: 421 NARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDG 480
NARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDG
Sbjct: 421 NARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDG 480
Query: 481 HPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA 540
HPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA
Sbjct: 481 HPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA 540
Query: 541 GTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGANRAPAALQ 600
GTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGANRAPAALQ
Sbjct: 541 GTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGANRAPAALQ 600
Query: 601 VRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHAPACGRAHT 660
VRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHAPACGRAHT
Sbjct: 601 VRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHAPACGRAHT 660
Query: 661 HAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPHTEVRLLHA 720
HAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPHTEVRLLHA
Sbjct: 661 HAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPHTEVRLLHA 720
Query: 721 RSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGVGCAVLGAR 780
RSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGVGCAVLGAR
Sbjct: 721 RSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGVGCAVLGAR 780
Query: 781 SEA 783
SEA
Sbjct: 781 SEA 783
>gi|239745948 PREDICTED: hypothetical protein XP_002343622 [Homo
sapiens]
Length = 791
Score = 1640 bits (4247), Expect = 0.0
Identities = 783/791 (98%), Positives = 783/791 (98%), Gaps = 8/791 (1%)
Query: 1 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH 60
MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH
Sbjct: 1 MSSARRVELALPITWLLAVARGRMMSSGHMAFSHWPAEAGLCSPDVSRGPGEPTYRNFVH 60
Query: 61 QGHLSGLVHTGQQLPIVPA--------LRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDG 112
QGHLSGLVHTGQQLPIVPA LRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDG
Sbjct: 61 QGHLSGLVHTGQQLPIVPATPQPLTQQLRKCSVSNFHIPIRPPGPEAKRTHGPSAAFQDG 120
Query: 113 QPPALPVTTGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVAL 172
QPPALPVTTGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVAL
Sbjct: 121 QPPALPVTTGQLPGTERPTCNRLIHGKGLVLHEHALTLLLFQDGLIAHAPGGVHVPLVAL 180
Query: 173 LWAGLGHLGDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGG 232
LWAGLGHLGDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGG
Sbjct: 181 LWAGLGHLGDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGG 240
Query: 233 CGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVA 292
CGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVA
Sbjct: 241 CGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVA 300
Query: 293 LRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREA 352
LRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREA
Sbjct: 301 LRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREA 360
Query: 353 DGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQD 412
DGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQD
Sbjct: 361 DGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQD 420
Query: 413 DGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQA 472
DGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQA
Sbjct: 421 DGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQA 480
Query: 473 HHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGP 532
HHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGP
Sbjct: 481 HHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGP 540
Query: 533 GWDGGARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGA 592
GWDGGARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGA
Sbjct: 541 GWDGGARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGA 600
Query: 593 NRAPAALQVRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHA 652
NRAPAALQVRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHA
Sbjct: 601 NRAPAALQVRALRLHRNKACPALPAPTHLQAEPTRTFRLVREMGVSGPAGVWVVAVDCHA 660
Query: 653 PACGRAHTHAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPH 712
PACGRAHTHAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPH
Sbjct: 661 PACGRAHTHAHSLSGLGLRRGNWCEGAALRTPHRVFQRARLRTRAGLPWRVSLAHVDTPH 720
Query: 713 TEVRLLHARSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGV 772
TEVRLLHARSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGV
Sbjct: 721 TEVRLLHARSFSGTSTSHQANLLKLDRRNWEANPGWYLSSPINKRFSGRLPPGLLASRGV 780
Query: 773 GCAVLGARSEA 783
GCAVLGARSEA
Sbjct: 781 GCAVLGARSEA 791
>gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo
sapiens]
Length = 492
Score = 44.7 bits (104), Expect = 3e-04
Identities = 55/189 (29%), Positives = 73/189 (38%), Gaps = 31/189 (16%)
Query: 459 GPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAG--GG 516
GP P Q+ Q+ H G + ++ + DSP P S W QL +
Sbjct: 273 GPPPALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTPGSWWEQLTQASRVYAS 332
Query: 517 RGWEGRGAGRWARPGPGWDG-GARAGTQGLPLPGTEAEPGALGCSLSR------GPVPRQ 569
G EG RWA PG G A G Q PLP E PG G L R GP +
Sbjct: 333 GGTEGFPLSRWA---PGRHGTAAEEGAQERPLPTDEMAPGR-GLWLGRLFGVPGGPAENE 388
Query: 570 GSLLSARVGWSLHHRYITSIQGANRAPAALQVRALRLHRNKACPALPAPTHLQAEPTR-- 627
L +R + ++ P + V L L + A P +P+P L+A R
Sbjct: 389 NGALKSR-------------RPSSWLPPTVSV--LALVKRGAPPEMPSPQELEASAPRMV 433
Query: 628 -TFRLVREM 635
T R VR +
Sbjct: 434 QTHRAVRAL 442
>gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo
sapiens]
Length = 902
Score = 44.7 bits (104), Expect = 3e-04
Identities = 55/189 (29%), Positives = 73/189 (38%), Gaps = 31/189 (16%)
Query: 459 GPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAG--GG 516
GP P Q+ Q+ H G + ++ + DSP P S W QL +
Sbjct: 683 GPPPALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTPGSWWEQLTQASRVYAS 742
Query: 517 RGWEGRGAGRWARPGPGWDG-GARAGTQGLPLPGTEAEPGALGCSLSR------GPVPRQ 569
G EG RWA PG G A G Q PLP E PG G L R GP +
Sbjct: 743 GGTEGFPLSRWA---PGRHGTAAEEGAQERPLPTDEMAPGR-GLWLGRLFGVPGGPAENE 798
Query: 570 GSLLSARVGWSLHHRYITSIQGANRAPAALQVRALRLHRNKACPALPAPTHLQAEPTR-- 627
L +R + ++ P + V L L + A P +P+P L+A R
Sbjct: 799 NGALKSR-------------RPSSWLPPTVSV--LALVKRGAPPEMPSPQELEASAPRMV 843
Query: 628 -TFRLVREM 635
T R VR +
Sbjct: 844 QTHRAVRAL 852
>gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo
sapiens]
Length = 433
Score = 44.7 bits (104), Expect = 3e-04
Identities = 55/189 (29%), Positives = 73/189 (38%), Gaps = 31/189 (16%)
Query: 459 GPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAG--GG 516
GP P Q+ Q+ H G + ++ + DSP P S W QL +
Sbjct: 214 GPPPALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDSPNLPTPGSWWEQLTQASRVYAS 273
Query: 517 RGWEGRGAGRWARPGPGWDG-GARAGTQGLPLPGTEAEPGALGCSLSR------GPVPRQ 569
G EG RWA PG G A G Q PLP E PG G L R GP +
Sbjct: 274 GGTEGFPLSRWA---PGRHGTAAEEGAQERPLPTDEMAPGR-GLWLGRLFGVPGGPAENE 329
Query: 570 GSLLSARVGWSLHHRYITSIQGANRAPAALQVRALRLHRNKACPALPAPTHLQAEPTR-- 627
L +R + ++ P + V L L + A P +P+P L+A R
Sbjct: 330 NGALKSR-------------RPSSWLPPTVSV--LALVKRGAPPEMPSPQELEASAPRMV 374
Query: 628 -TFRLVREM 635
T R VR +
Sbjct: 375 QTHRAVRAL 383
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 44.7 bits (104), Expect = 3e-04
Identities = 47/230 (20%), Positives = 83/230 (36%), Gaps = 32/230 (13%)
Query: 314 DLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLH 373
++ +G+ + E+ G +E EG++ + E +GE +EE G G E G
Sbjct: 818 EVEEGKGEREEEEEEGEGEE----EEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873
Query: 374 HTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAP 433
G+ E EE +G +EE G G +GE +++GE + + G ++
Sbjct: 874 GEGEGEEEEGEGEGEEEGEGE------GEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEE 927
Query: 434 RPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALT 493
+ +G + G E+EE + + +G +G G
Sbjct: 928 GEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGE--------- 978
Query: 494 WDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARAGTQ 543
G+ + + G G G E G G G + G G +
Sbjct: 979 -------------GEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEE 1015
Score = 38.1 bits (87), Expect = 0.032
Identities = 34/139 (24%), Positives = 54/139 (38%), Gaps = 2/139 (1%)
Query: 339 EVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAP 398
E EG + E +G KEE GGEV G+ E EE +G +EE ++
Sbjct: 788 EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVE-EGKGEREEEEEEGEGEEEEGEGEEEE 846
Query: 399 FLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGV-EALAAAGWDMA 457
G +GE +++GE G+ + + + +G E G
Sbjct: 847 GEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEE 906
Query: 458 LGPGPWEQEERQSQAHHQG 476
G G E+EE + + +G
Sbjct: 907 EGEGEGEEEEGEGKGEEEG 925
Score = 37.4 bits (85), Expect = 0.054
Identities = 50/228 (21%), Positives = 81/228 (35%), Gaps = 52/228 (22%)
Query: 188 EEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDPMLTPALV 247
EE+EG G EG+G+ ++ G G GEE +
Sbjct: 829 EEEEGEGEEEEGEGE-----------------EEEGEGEEEEGEGKGEEEGEE------- 864
Query: 248 AATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQGDDQ 307
G G +EG + + E ++ G+G G G +G+++
Sbjct: 865 -----GEGEEEGEEGE----GEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915
Query: 308 PLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRGTG 367
+G+ + E G E EG+D + E +GE +EE G G
Sbjct: 916 ---------EGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEG 966
Query: 368 GEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGE 415
E G+ E EE +G +EE + G +GE +++GE
Sbjct: 967 EE-----EGEGEGEEGEGEGEEE-----EGEGEGEEEEGEEEGEEEGE 1004
Score = 33.9 bits (76), Expect = 0.60
Identities = 33/171 (19%), Positives = 69/171 (40%), Gaps = 12/171 (7%)
Query: 316 YQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRG-------TGG 368
+Q +++ E G + PG+ + + ++ DGE+ ++E +G
Sbjct: 669 WQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEME 728
Query: 369 EVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGL 428
E G G+ E EE ++EE G + G +GE +++GE K+ + A
Sbjct: 729 EGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGER-EKEEGERKKEERAGKEEKG 787
Query: 429 QDDAPRPRAVTQVV----VQGVEALAAAGWDMALGPGPWEQEERQSQAHHQ 475
+++ + + + E G ++ G G E+EE + + +
Sbjct: 788 EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE 838
Score = 32.0 bits (71), Expect = 2.3
Identities = 46/209 (22%), Positives = 78/209 (37%), Gaps = 40/209 (19%)
Query: 188 EEDEGPGIG---GEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDPMLTP 244
EE+EG G G GEG+G+ G + G G G EE +
Sbjct: 896 EEEEGEGEGEEEGEGEGEEEEGEG-----------KGEEEGEEGEGEGEEEEGEG----- 939
Query: 245 ALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQG 304
+G G EG +++ E + G+ G G G +G
Sbjct: 940 ------EGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEG---EGEEEEGEGEG 990
Query: 305 DDQPLCIDDDLYQGQQQSHSEDH-PAPGPVVLPGQ---EVEGKDVSRQTREADGEQNPKE 360
+++ + +G+++ E+ G G+ EVEG++ + E +GE+ +E
Sbjct: 991 EEE-----EGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEE 1045
Query: 361 EAPRGTGGEVGLHHTGKHEAEEAQGPQKE 389
G G E + + E EE +G +E
Sbjct: 1046 REKEGEGEE---NRRNREEEEEEEGKYQE 1071
Score = 30.8 bits (68), Expect = 5.1
Identities = 52/250 (20%), Positives = 89/250 (35%), Gaps = 43/250 (17%)
Query: 188 EEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDPMLTPALV 247
EE+EG G EG+G+ G + G G GEE +
Sbjct: 836 EEEEGEGEEEEGEGEEEEGEG-----------KGEEEGEEGEGEEEGEEGE--------- 875
Query: 248 AATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQGDDQ 307
G G +E + + + E + G+G G G +G+++
Sbjct: 876 -----GEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEG------EGEEEEGEGKGEEE 924
Query: 308 PLCIDDDLYQGQQQSHSEDHPAPGPVV---LPGQEVEGKDVSRQTREADGEQNPKEEAPR 364
+ + + + + ED G G+E EG+ + E +GE+ E
Sbjct: 925 GEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEE 984
Query: 365 GTGGEVGLHHTGKHEAEE-AQGPQ------KEEYLGPQQAPFLGVLHKGEAGHQDDGEHK 417
GE G G+ E EE +G + +EE G + G +GE G +++GE +
Sbjct: 985 EGEGE-GEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGE-GEEEEGEEE 1042
Query: 418 RGDNARPSHG 427
+ + G
Sbjct: 1043 GEEREKEGEG 1052
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 42.4 bits (98), Expect = 0.002
Identities = 123/469 (26%), Positives = 161/469 (34%), Gaps = 96/469 (20%)
Query: 177 LGHLGDLGDDVEEDEGPGIGGEGD-GQRGVI-PGGTVVLLVAVSIHDDPHHPYGNGGGCG 234
+G GD GD E+ G G G RG P G LV G G G
Sbjct: 1669 VGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTG---PGAREKGEPGDRG 1725
Query: 235 EEH-KDPMLTPALVAAT--------QGGPGPQEGTQQQQHDVDECHDKVHVG-DGTGGGH 284
+E + P P L A +G PGPQ G + E D+ G DG G
Sbjct: 1726 QEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQ-GDPGVRGPAGEKGDRGPPGLDGRSGLD 1784
Query: 285 GPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKD 344
G AA + PN + D G + P+ GP LPG+ G+D
Sbjct: 1785 GKPGAAGP------SGPNGAAGKAGDPGRDGLPGLRGEQGLPGPS-GPPGLPGKP--GED 1835
Query: 345 VSRQTREADGEQ-NPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEE----YLGPQQAPF 399
+GE +P E+ +G G+ +G E GP+ E LGPQ P
Sbjct: 1836 GKPGLNGKNGEPGDPGEDGRKGEKGD-----SGASGREGRDGPKGERGAPGILGPQGPPG 1890
Query: 400 L----------------GVLHKGEAGHQDDGEHKRGDNARPSH-GLQDDAPRPRAVTQVV 442
L G KG+ G +G+ P GL+ + V +++
Sbjct: 1891 LPGPVGPPGQGFPGVPGGTGPKGDRGETGS----KGEQGLPGERGLRGEPGSVPNVDRLL 1946
Query: 443 -VQGVEALA----AAGWDMALGP---------GPWEQEERQSQAHHQGFVD--------- 479
G++A A WD + G GP Q +G +
Sbjct: 1947 ETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKG 2006
Query: 480 --GHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGR--GAGRWARPGPGWD 535
G PG Q LAL PP P + +P G G GR G G RPG +
Sbjct: 2007 DRGDPGPQGPPGLALGERGPPGPSGLAG----EPGKPGIPGLPGRAGGVGEAGRPGERGE 2062
Query: 536 GGARA-----GTQGLP-LPGTEAEPGALGCSLSRGPVPRQGSLLSARVG 578
G + G G P LPGT PG G +S V G LS G
Sbjct: 2063 RGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVS---VDEPGPGLSGEQG 2108
Score = 41.6 bits (96), Expect = 0.003
Identities = 97/363 (26%), Positives = 129/363 (35%), Gaps = 63/363 (17%)
Query: 226 PYGNGGGCGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGD----GTG 281
P G+ G GE+ DP G PGP G + + +V E D+ GD G
Sbjct: 1605 PPGDSGPPGEKG-DP--------GRPGPPGPV-GPRGRDGEVGEKGDEGPPGDPGLPGKA 1654
Query: 282 GGHGPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSE--DHPAPGPVVLPGQE 339
G G A +R + +QGD +D G S D PGP PG+
Sbjct: 1655 GERGLR-GAPGVRGPVGEKGDQGDP-----GEDGRNGSPGSSGPKGDRGEPGPPGPPGRL 1708
Query: 340 VEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHT-GKHEAEEAQGPQKEEYLGPQQAP 398
V D RE + +E PRG G+ GL G+ E +GP GPQ P
Sbjct: 1709 V---DTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPP-----GPQGDP 1760
Query: 399 FLGVLHKGEAGHQDDG-----EHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAG 453
GV +G AG + D + + G + +P G + A + G + L
Sbjct: 1761 --GV--RGPAGEKGDRGPPGLDGRSGLDGKP--GAAGPSGPNGAAGKAGDPGRDGLPGLR 1814
Query: 454 WDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQA 513
+ L PGP + G PG + L P P + G+
Sbjct: 1815 GEQGL-PGP----------SGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSG 1863
Query: 514 GGGRGWEGRGAGRWARPGPGWDGGARAGTQGLPLP------GTEAEPGALGCSLSRGPVP 567
GR EGR + R PG G G GLP P G PG G RG
Sbjct: 1864 ASGR--EGRDGPKGERGAPGILG--PQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETG 1919
Query: 568 RQG 570
+G
Sbjct: 1920 SKG 1922
Score = 41.2 bits (95), Expect = 0.004
Identities = 72/257 (28%), Positives = 89/257 (34%), Gaps = 29/257 (11%)
Query: 328 PAP-GPVVLPGQEVEGKDVSRQTREADGEQ-NPKEEAPRGTGGEVGLHHTGKHEAEEAQG 385
P P GPV PG++ E D G+ +P E+ PRG G +G +
Sbjct: 1432 PGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEA 1491
Query: 386 PQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSH-GLQDDAPRPRAVTQVVVQ 444
+K E P A G+ G AG +G P G Q + P V
Sbjct: 1492 GEKGERGPPGPAGSRGL--PGVAGRPG----AKGPEGPPGPTGRQGEKGEPGRPGDPAVV 1545
Query: 445 GVEALAAAGWDMALGP-GPWEQEERQSQAHHQGFV-DGHPGSQARLWLALTWDSPPAPLQ 502
G G +GP GP Q + G V G PG + D P L
Sbjct: 1546 GPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGD-----PGDRGPIGLT 1600
Query: 503 RSVWGQLQPQAGGGRGWEGRGAGRWARPGP----GWDGGA-RAGTQGLP----LPGTEAE 553
G+ P G E GR PGP G DG G +G P LPG E
Sbjct: 1601 ----GRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGE 1656
Query: 554 PGALGCSLSRGPVPRQG 570
G G RGPV +G
Sbjct: 1657 RGLRGAPGVRGPVGEKG 1673
Score = 37.4 bits (85), Expect = 0.054
Identities = 35/113 (30%), Positives = 44/113 (38%), Gaps = 11/113 (9%)
Query: 460 PGPWEQEERQSQAHHQGF--VDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGR 517
PGP + +GF DG PGS R +P P + G P G R
Sbjct: 1283 PGPQGPPGSATAKGERGFPGADGRPGSPGRA------GNPGTPGAPGLKGS--PGLPGPR 1334
Query: 518 GWEGRGAGRWARPGPGWDGGARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQG 570
G G R + PG G G +G LPG + +PG G RGP+ G
Sbjct: 1335 GDPGERGPRGPKGEPGAPGQVIGG-EGPGLPGRKGDPGPSGPPGPRGPLGDPG 1386
Score = 35.0 bits (79), Expect = 0.27
Identities = 64/238 (26%), Positives = 82/238 (34%), Gaps = 61/238 (25%)
Query: 336 PGQEVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQ 395
PGQ + G+ R+ D P P G G +G GP+ GP
Sbjct: 1352 PGQVIGGEGPGLPGRKGD----PGPSGPPGPRGPLG-----------DPGPR-----GPP 1391
Query: 396 QAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAA-GW 454
P G KG+ G RG+ P G AP G+ L + G
Sbjct: 1392 GLP--GTAMKGDKGD-------RGERGPPGPGEGGIAPGE--------PGLPGLPGSPGP 1434
Query: 455 DMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAG 514
+GP + E+ S+ G + G PGS P P G + P+
Sbjct: 1435 QGPVGPPGKKGEKGDSEDGAPG-LPGQPGSPGE-------QGPRGPP-----GAIGPK-- 1479
Query: 515 GGRGWEGR--GAGRWARPGPGWDGGARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQG 570
G RG+ G AG GP G+R LPG PGA G GP RQG
Sbjct: 1480 GDRGFPGPLGEAGEKGERGPPGPAGSRG------LPGVAGRPGAKGPEGPPGPTGRQG 1531
Score = 34.7 bits (78), Expect = 0.35
Identities = 66/261 (25%), Positives = 86/261 (32%), Gaps = 43/261 (16%)
Query: 327 HPAPGPVVLPGQE-VEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQG 385
H PGP PG G + GE P G G VGL
Sbjct: 2182 HGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGP---------- 2231
Query: 386 PQKEEYLGPQQAPFL----GVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQV 441
P +GPQ +P L G K A +D K GD P P P V
Sbjct: 2232 PGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGP-----V 2286
Query: 442 VVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPL 501
+G A +G P + E+ + G + G PG++ L P P
Sbjct: 2287 GPKGEPGPTGAPGQAVVGL-PGAKGEKGAPGGLAGDLVGEPGAKGDRGL-------PGPR 2338
Query: 502 -QRSVWGQL----------QPQAGGGRGWEGR-GAGRWARPGPGWDGGARAGTQGLPLPG 549
++ G+ Q A G +G++G G G PGP G + L LPG
Sbjct: 2339 GEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGD---LGLPG 2395
Query: 550 TEAEPGALGCSLSRGPVPRQG 570
PG +G GP G
Sbjct: 2396 LPGAPGVVGFPGQTGPRGEMG 2416
Score = 32.7 bits (73), Expect = 1.3
Identities = 88/333 (26%), Positives = 112/333 (33%), Gaps = 57/333 (17%)
Query: 330 PGPVVLPGQEVEGKDVSRQTREAD-GEQNPK-EEAPRGTGGEVGLHHT-------GKHEA 380
PG +PG V R + GE+ K E +G G GL T G +
Sbjct: 2036 PGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVS 2095
Query: 381 EEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHK--------RGDNARPSHGLQDDA 432
+ GP GP KGE G D K +GD P QD
Sbjct: 2096 VDEPGPGLSGEQGPPGLKGA----KGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGN 2151
Query: 433 PR-PRAVTQVVVQGVEALAAA-GWDMALG----PGPWEQEERQSQAHHQG--FVDGHPGS 484
P P +G L G +G PGP A QG + G PG
Sbjct: 2152 PGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGE 2211
Query: 485 QARLWLALTWDS-------PPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPG-PGWDG 536
LT + PP P G + PQ G G G+ G +PG PG DG
Sbjct: 2212 TGPPGRGLTGPTGAVGLPGPPGPS-----GLVGPQ--GSPGLPGQ-VGETGKPGAPGRDG 2263
Query: 537 GA-RAGTQGLP-LPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYITSIQGANR 594
+ + G +G P +PG+ PG +G GP G A VG + +G
Sbjct: 2264 ASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPG---QAVVG-------LPGAKGEKG 2313
Query: 595 APAALQVRALRLHRNKACPALPAPTHLQAEPTR 627
AP L + K LP P + E R
Sbjct: 2314 APGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGR 2346
>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
Length = 686
Score = 41.2 bits (95), Expect = 0.004
Identities = 97/386 (25%), Positives = 128/386 (33%), Gaps = 80/386 (20%)
Query: 204 GVIPGGTVVLLVAVSIHDDPHHPYGNGGGC----GEEHKDPMLTPALVAATQGGPGPQEG 259
GV PG V + + P P GG G E + A GG GP G
Sbjct: 9 GVAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRG 68
Query: 260 TQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQ 319
+ + H + +G G A P G++ G
Sbjct: 69 PEAEARGTRGAHGETEAEEGAPEG--------------AEVPQGGEET---------SGA 105
Query: 320 QQSHSEDHPAPGPVVLPGQEV--EGKDVSRQTREADGEQNPKEEAPRGT-GGEVGLHHTG 376
QQ P G P E E +D + R+ + EQ P E P G+ GE G
Sbjct: 106 QQVEGAS-PGRGAQGEPRGEAQREPEDSAAPERQEEAEQRP--EVPEGSASGEAG----- 157
Query: 377 KHEAEEAQGPQKE--EYLGP-----QQAPFLG--VLHKGEAGHQDDGEHKRGDNARPSHG 427
++ +A+GP + E GP + +G V +G AG D E GDN +
Sbjct: 158 --DSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGP 215
Query: 428 LQD------------DAPRPRAVTQVVVQG-----VEALAAAGWDMALGPGPWEQEERQS 470
D DA P A V +G VEA AG + G + E +
Sbjct: 216 AGDSVDAEGRVGDSVDAEGP-AGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEG 274
Query: 471 QAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARP 530
A +G G R+ Q+S G L PQA G AGR P
Sbjct: 275 PAGDSMDAEGPAGRARRV---------SGEPQQSGDGSLSPQAEAIEVAAGESAGR--SP 323
Query: 531 GP-GWDGGARAGTQGLPLPGTEAEPG 555
G WD A G+ EA PG
Sbjct: 324 GELAWDAAEEAEVPGVK-GSEEAAPG 348
Score = 31.2 bits (69), Expect = 3.9
Identities = 57/234 (24%), Positives = 89/234 (38%), Gaps = 24/234 (10%)
Query: 337 GQEVEGKDVSRQTREADGEQNPKEEA--PRGTGGEVGLHHTGKHEAE-------EAQGP- 386
G V+ + + + +A+G EA P G G E G+ EAE +A+GP
Sbjct: 227 GDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPA 286
Query: 387 -QKEEYLG-PQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQ 444
+ G PQQ+ + + EA GE + ++A P
Sbjct: 287 GRARRVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAA 346
Query: 445 GVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRS 504
+A A AG D +G GP +QE + + + +G +A + DS +P +
Sbjct: 347 PGDARADAGEDR-VGDGP-QQEPGEDEERRERSPEGPREEEAAGGEEESPDS--SPHGEA 402
Query: 505 VWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARAGTQGLPLPGTEAEPGALG 558
G +P+A + + A GP G A G G +EP ALG
Sbjct: 403 SRGAAEPEA--------QLSNHLAEEGPAEGSGEAARVNGRREDGEASEPRALG 448
Score = 30.8 bits (68), Expect = 5.1
Identities = 73/331 (22%), Positives = 107/331 (32%), Gaps = 65/331 (19%)
Query: 155 DGLIAHAPGGVHVPLVALLWAGLGHLGDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLL 214
D + A P G V L + G GD V+ + G + +G G +V
Sbjct: 188 DSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAG----DSVDAE 243
Query: 215 VAVSIHDDPHHPYGNGGGCGEEHKDPMLTPALVAATQGGPGPQ------EGTQQQQHD-- 266
V + P G+G G D + + GP G QQ D
Sbjct: 244 GRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGS 303
Query: 267 VDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSED 326
+ + + V G G P A +G ++ D G ED
Sbjct: 304 LSPQAEAIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAG------ED 357
Query: 327 HPAPGPVVLPGQEVEGKDVS----RQTREADGEQNPKEEAPRG---TGGEVGLHHTGKHE 379
GP PG++ E ++ S R+ A GE+ + +P G G H
Sbjct: 358 RVGDGPQQEPGEDEERRERSPEGPREEEAAGGEEESPDSSPHGEASRGAAEPEAQLSNHL 417
Query: 380 AEEAQGPQKEEYLGPQQAPFLGVLHKGEA----GHQDDGEHKRGDNARPSHGLQDDAPRP 435
AEE GP + GEA G ++DGE A P
Sbjct: 418 AEE----------GPAEG-------SGEAARVNGRREDGE----------------ASEP 444
Query: 436 RAVTQVVVQGVEALAAAGWD-MALGPGPWEQ 465
RA+ Q + AG+D ++G P+ Q
Sbjct: 445 RALGQ--EHDITLFVKAGYDGESIGNCPFSQ 473
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 40.8 bits (94), Expect = 0.005
Identities = 70/338 (20%), Positives = 118/338 (34%), Gaps = 48/338 (14%)
Query: 254 PGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVAL--RAALATAPNQGDDQPLCI 311
P + Q + DV+ + V + G P A ++ +G+D+P
Sbjct: 1877 PEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESE 1936
Query: 312 DDDLYQGQQQSH-SEDHPAPGPVVLPGQE-----------VEGKDVSRQTREADGEQNPK 359
+ + ++ + +E P V+ QE VE +V +T+EA+GE P+
Sbjct: 1937 GAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPE 1996
Query: 360 E---EAPRGTG-----------GEVGLHHTGKHEAEEAQ----GPQKEEYLGPQQAPFLG 401
EAP G G+ K E EEAQ QK E ++ +
Sbjct: 1997 SEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVE 2056
Query: 402 VLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPG 461
E + +GE + + DA Q +GVEA A G
Sbjct: 2057 APEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGI 2116
Query: 462 PWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEG 521
+ E ++Q +G +A+ + G+ QP++ G E
Sbjct: 2117 EAPETEGEAQPESEGIEAPEAEGEAQ-------PESEGVEAQDAEGEAQPES---EGIEA 2166
Query: 522 RGAGRWARP------GPGWDGGARAGTQGLPLPGTEAE 553
+ A A+P P +G A+ ++G+ P E E
Sbjct: 2167 QEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGE 2204
Score = 31.6 bits (70), Expect = 3.0
Identities = 70/319 (21%), Positives = 103/319 (32%), Gaps = 78/319 (24%)
Query: 161 APGGVHVPLVALLWAGLGHLGDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIH 220
APG H + G G LG + + G G +G+G + ++
Sbjct: 1709 APGKTHTDPTSTRTVQ-GAEGGLGPGLSQGPGVDEGEDGEGSQ------------RLNRD 1755
Query: 221 DDPHHPYGNGGGCGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGT 280
DP G +E + A ++ G QEG + ++ G G
Sbjct: 1756 KDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEG--------EGISERGETG-GQ 1806
Query: 281 GGGHGPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEV 340
G GH A A P Q D I+ +G+ Q SE AP E
Sbjct: 1807 GSGHEDNLQGEAA-AGGDQDPGQSDGAE-GIEAPEAEGEAQPESEGVEAP--------EA 1856
Query: 341 EGKDVSRQTREADGEQNPKE---EAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQA 397
EG +EA+GE P+ EAP G + E+E+ + P+ E + P+
Sbjct: 1857 EG-----DAQEAEGEAQPESEDVEAPEAEG-------EAQPESEDVETPEAEWEVQPE-- 1902
Query: 398 PFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMA 457
S G +AP Q + VEAL G D
Sbjct: 1903 ---------------------------SEGA--EAPEAEKEAQPETESVEALETEGEDEP 1933
Query: 458 LGPGPWEQEERQSQAHHQG 476
G QE ++ +G
Sbjct: 1934 ESEGAEAQEAEEAAQEAEG 1952
Score = 30.8 bits (68), Expect = 5.1
Identities = 25/109 (22%), Positives = 39/109 (35%), Gaps = 14/109 (12%)
Query: 317 QGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTG 376
+G + +E+ P P + E EG+ E GE+ + G G
Sbjct: 2210 EGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDG--------Q 2261
Query: 377 KHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPS 425
EA E+ P E+ P +P G+ HQ G ++R S
Sbjct: 2262 SEEASESSSPVPEDRPTPPPSP------GGDTPHQRPGSQTGPSSSRAS 2304
>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
Length = 1714
Score = 40.0 bits (92), Expect = 0.008
Identities = 71/267 (26%), Positives = 96/267 (35%), Gaps = 53/267 (19%)
Query: 331 GPVVLPGQE-VEGKDVSRQTREADGEQNPKEE-------APRGTGGEVGL----HHTGKH 378
GPV LPG+ + G + R + G P+ E P G G +G H G
Sbjct: 855 GPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGAR 914
Query: 379 EAEEAQGPQKEE-YLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRA 437
+QGP+ + GP G+L GE G Q K R HGL P
Sbjct: 915 GPPGSQGPKGQRGSRGPD-----GLL--GEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGE 967
Query: 438 VTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFV--DGHPGSQARLWLALTWD 495
G++ L + D L PG Q G + +G PG++ L
Sbjct: 968 RGFQGKPGLQGLPGSTGDRGL-PGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGL----- 1021
Query: 496 SPPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPG-------PGWDG-GARAGTQGLP- 546
Q +P A G G G G PG PG +G + G +G+P
Sbjct: 1022 ------------QGEPGAKGDVGTAG-SVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPG 1068
Query: 547 ---LPGTEAEPGALGCSLSRGPVPRQG 570
LPG + E G +G GP+ R G
Sbjct: 1069 GRGLPGEDGEKGEMGLPGIIGPLGRSG 1095
Score = 35.8 bits (81), Expect = 0.16
Identities = 67/273 (24%), Positives = 91/273 (33%), Gaps = 42/273 (15%)
Query: 303 QGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEA 362
QG++ P+ +L + PGP L G+ + ++ + E
Sbjct: 806 QGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIG----------ETG 855
Query: 363 PRGTGGEVGLHHTGKHEAEEAQ----GPQKEE----YLGPQQAPF-LGVL----HKGEAG 409
P G GEVG+ + + E GPQ E+ Y GP P +G L H G G
Sbjct: 856 PVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARG 915
Query: 410 HQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQ 469
K +R GL + QG++ D GP +
Sbjct: 916 PPGSQGPKGQRGSRGPDGLLGE------------QGIQGAKGEKGDQGKR-GPHGLIGKT 962
Query: 470 SQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGR----GWEGRGAG 525
+GF G PG Q P P R + G + P G G EG +G
Sbjct: 963 GNPGERGF-QGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGE-SG 1020
Query: 526 RWARPGPGWDGGARAGTQGLPLPGTEAEPGALG 558
PG D G G PG EPGA G
Sbjct: 1021 LQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPG 1053
>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
Length = 2263
Score = 39.7 bits (91), Expect = 0.011
Identities = 76/292 (26%), Positives = 104/292 (35%), Gaps = 61/292 (20%)
Query: 277 GDGTGGGHGPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLP 336
GDGT G GP R ++G Y G++ E APGPV
Sbjct: 1393 GDGTMGDPGPP----GKRGPPGFKGSEG-----------YLGEEGIAGE-RGAPGPVGEQ 1436
Query: 337 GQEVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQ 396
G T+ G + PK RG G+ G G++ + G Q + L ++
Sbjct: 1437 G-----------TKGCYGTKGPKGN--RGLNGQEG--EVGENGIDGLNGEQGDNGLPGRK 1481
Query: 397 APFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAA---- 452
KG+ G Q + R + GL+ D P + + +G L
Sbjct: 1482 G------EKGDEGSQGSPGKRGTPGDRGAKGLRGDPGAPGVDSSI--EGPTGLKGERGRQ 1533
Query: 453 ---GWDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVW--G 507
GW GP R++ AH + GH G Q + P L+ S+ G
Sbjct: 1534 GRRGWP---GPPGTPGSRRKTAAHGRR---GHTGPQGTAGIP-----GPDGLEGSLGLKG 1582
Query: 508 QLQPQAGGGRGWEGRGAGRWARPGPGWDGGARAGTQG-LPLPGTEAEPGALG 558
P+ G E G G GP GG AG QG L G + EPG LG
Sbjct: 1583 PQGPRGEAGVKGEKGGVGSKGPQGPPGPGG-EAGNQGRLGSQGNKGEPGDLG 1633
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 39.7 bits (91), Expect = 0.011
Identities = 56/235 (23%), Positives = 76/235 (32%), Gaps = 38/235 (16%)
Query: 361 EAPRGTGGEVGLHHTGKHEAEEAQ--GPQKEEYLGPQQAPFLGVLHKGEAG---HQDDGE 415
+ PR + HH G + +Q GP + Y + P G+ E G H E
Sbjct: 3585 DKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKE 3644
Query: 416 HKRGDNARPSHGLQDDAPRPRAV-------------TQVVVQGVEALAAAGWDMALGPGP 462
H+ GD+ R S + P RA A+ G
Sbjct: 3645 HRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAE 3704
Query: 463 WEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGR 522
+ Q R S A+H D GS+ S PA LQ Q QPQ
Sbjct: 3705 YSQPSRASSAYHHA-SDSKKGSRQA-------HSGPAALQSKAEPQAQPQL--------- 3747
Query: 523 GAGRWARPGPGWDGGARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARV 577
GR A PGP ++ +P +P G P Q +L AR+
Sbjct: 3748 -QGRQAAPGP--QQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARL 3799
>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
Length = 1860
Score = 39.7 bits (91), Expect = 0.011
Identities = 68/248 (27%), Positives = 90/248 (36%), Gaps = 53/248 (21%)
Query: 317 QGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQN-PKEEAPRGTGGEVGLHHT 375
+G++ ED A GP PG G R R G+ P +E +G G+ G
Sbjct: 1326 KGEKGEQGEDGKAEGPPGPPGDR--GPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQ 1383
Query: 376 GKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRP 435
H P + GP+ + KG G + R GLQ P P
Sbjct: 1384 PGH-------PGPRGWPGPKGS-------KGAEGPKGKQGKAGAPGRRGVQGLQG-LPGP 1428
Query: 436 RAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFV--DGHPGSQARLWLALT 493
R V V QG+E +A GP R QA QG DG PG
Sbjct: 1429 RGV--VGRQGLEGIA----------GPDGLPGRDGQAGQQGEQGDDGDPGPMG------- 1469
Query: 494 WDSPPAPLQRSVWGQLQPQAGGGRGWEGRGA--GRWARPGPGWDGGARAGTQGLP-LPGT 550
PA + + P A G G++G G+ PG + GT+G LPG
Sbjct: 1470 ----PAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPG-------KRGTEGRTGLPGN 1518
Query: 551 EAEPGALG 558
+ EPG+ G
Sbjct: 1519 QGEPGSKG 1526
Score = 32.3 bits (72), Expect = 1.7
Identities = 65/247 (26%), Positives = 87/247 (35%), Gaps = 56/247 (22%)
Query: 358 PKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEY-LGPQQAPFLGVLHKGEAGHQDDGEH 416
P + P G G+ G G GP+ +E +GP AP L +G+ G
Sbjct: 918 PGDNGPEGMKGKPGAR--GLPGPRGQLGPEGDEGPMGPPGAPGL----EGQPG------- 964
Query: 417 KRGDNARPS----HGLQDDAPRPRAVTQ------VVVQGVEALAAAGWDMALGPGPWEQE 466
++G RP G D RP V + + + G + D + P
Sbjct: 965 RKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPG 1024
Query: 467 ERQSQAHHQGF-----VDGHPGSQARLWLALTWDSPPA----PLQRSVWGQLQPQ----- 512
+ S H G G PG Q PP P R G+ P+
Sbjct: 1025 PKGSMGH-PGMPGGMGTPGEPGPQG----------PPGSRGPPGMRGAKGRRGPRGPDGP 1073
Query: 513 AG--GGRGWEGRGA--GRWARPGPGWDGGARA--GTQGLP-LPGTEAEPGALGCSLSRGP 565
AG G RG +G GR RPG G R G++G P +PG PG G GP
Sbjct: 1074 AGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGP 1133
Query: 566 VPRQGSL 572
QG +
Sbjct: 1134 QGPQGPI 1140
Score = 32.0 bits (71), Expect = 2.3
Identities = 95/362 (26%), Positives = 124/362 (34%), Gaps = 70/362 (19%)
Query: 228 GNGGGCGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGP- 286
G G GE+ M+ P V +G G H + G GT G GP
Sbjct: 1003 GEPGIVGEKGDRGMMGPPGVPGPKGSMG---------------HPGMPGGMGTPGEPGPQ 1047
Query: 287 ----ACAAVALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPG----Q 338
+ +R A +G D P G+Q S P PGP PG Q
Sbjct: 1048 GPPGSRGPPGMRGAKGRRGPRGPDGPA--------GEQGSRGLKGP-PGPQGRPGRPGQQ 1098
Query: 339 EVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAP 398
V G+ +R G P P GT G G G + GP E +GP+ P
Sbjct: 1099 GVAGERGHLGSRGFPGIPGPS--GPPGTKGLPG--EPGPQGPQGPIGPPGE--MGPKGPP 1152
Query: 399 FLGVLHK----GEAGHQDDGEHKRGDNARPSH-GLQDDAPRPRAVTQVVVQGVEALAAAG 453
G + + GEAG + D G P GL P G + L
Sbjct: 1153 --GAVGEPGLPGEAGMKGD----LGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDR 1206
Query: 454 WDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQA 513
D PGP + + Q G DG PG +T P + + A
Sbjct: 1207 GD----PGPDGEHGEKGQEGLMG-EDGPPGPPG-----VTGVRGPEGKSGKQGEKGRTGA 1256
Query: 514 GGGRGWEGRGAGRWARPG----PGWDG--GARA--GTQGLP-LPGTEAEPGALGCSLSRG 564
G +G++G+ G PG PG G G+R G G P G + EPG G +G
Sbjct: 1257 KGAKGYQGQ-LGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKG 1315
Query: 565 PV 566
V
Sbjct: 1316 IV 1317
Score = 30.8 bits (68), Expect = 5.1
Identities = 26/69 (37%), Positives = 31/69 (44%), Gaps = 7/69 (10%)
Query: 508 QLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA--GTQGLP----LPGTEAEPGALGCSL 561
Q QP G G +G GR PGP D G + G GLP LPG++ E G G
Sbjct: 723 QGQPGPEGSPGAKGY-PGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPG 781
Query: 562 SRGPVPRQG 570
RG + G
Sbjct: 782 KRGKMGMPG 790
>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
Length = 1125
Score = 39.7 bits (91), Expect = 0.011
Identities = 64/231 (27%), Positives = 85/231 (36%), Gaps = 69/231 (29%)
Query: 357 NPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDG-- 414
+P + P GT G G+ +G + GP+ P G KGEAG + G
Sbjct: 246 DPGDPGPPGTHGNPGI-----------KGER-----GPKGNP--GNAQKGEAGERGPGGI 287
Query: 415 ------EHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEER 468
+ +RG+ +P G++ D P +G++ + D PGP
Sbjct: 288 PGYKGDKGERGECGKP--GIKGDKGSPGPYGPKGPRGIQGITGPPGD----PGP------ 335
Query: 469 QSQAHHQGFVD--GHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGR---- 522
+GF G PG + SP AP G Q G RG EGR
Sbjct: 336 ------KGFQGNKGEPGPPG------PYGSPGAP------GIGQQGIKGERGQEGRPGAP 377
Query: 523 ---GAGRWARPGPGWDGGARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQG 570
G G +PGP G G +GLP E PG G S GP QG
Sbjct: 378 GPIGVGEPGQPGPRGPEGV-PGERGLP---GEGFPGPKGEKGSEGPTGPQG 424
>gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]
Length = 1597
Score = 39.3 bits (90), Expect = 0.014
Identities = 43/181 (23%), Positives = 64/181 (35%), Gaps = 20/181 (11%)
Query: 296 ALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGE 355
+L Q +++ D+ Q + S E+HPA E + S GE
Sbjct: 158 SLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPA---------ETNQNEGSESGTIRQGE 208
Query: 356 QNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGE 415
+ P EE G L H + + E QG Q+ + G G L + GE
Sbjct: 209 ELPPEELQESQG----LLHPQEVQVLEEQGQQEAGFRGE------GTLREDVCADGLLGE 258
Query: 416 HKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQ 475
+ + G Q + QG E + G L G WEQE+ + +A Q
Sbjct: 259 EQMIEQVNDEKGEQKQKQEQVQDVMLGRQG-ERMGLTGEPEGLNDGEWEQEDMERKAQGQ 317
Query: 476 G 476
G
Sbjct: 318 G 318
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 38.9 bits (89), Expect = 0.019
Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 25/140 (17%)
Query: 272 DKVHVGDGTGGGHGP-------ACAAVA-LRAALATAPNQGDDQP----LCIDDDLYQGQ 319
D+ +G G G P A +A++ L +LA P + P L + +
Sbjct: 250 DRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPA 309
Query: 320 QQSHSEDHPA----PGPVVLPGQEVEGKDV-SRQTREADGEQNPKEEAPRGTGG-----E 369
Q ++D P+ P P PG+E G V + +GE++ E+APRG+ G E
Sbjct: 310 AQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPE 369
Query: 370 VG---LHHTGKHEAEEAQGP 386
VG G+ EEAQGP
Sbjct: 370 VGEDAPQRLGEEPEEEAQGP 389
>gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like
[Homo sapiens]
Length = 484
Score = 38.5 bits (88), Expect = 0.024
Identities = 42/181 (23%), Positives = 64/181 (35%), Gaps = 20/181 (11%)
Query: 296 ALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGE 355
+L Q +++ D+ Q + S E+HPA E + + GE
Sbjct: 158 SLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPA---------ETNQNEGAESGTIRQGE 208
Query: 356 QNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGE 415
+ P EE G L H + + E QG Q+ + G G L + GE
Sbjct: 209 ELPSEELQESQG----LLHPQEVQVLEEQGQQEAGFRGE------GTLREDVCADGLLGE 258
Query: 416 HKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQ 475
+ + G Q + QG E + G L G WEQE+ + +A Q
Sbjct: 259 EQMIEQVNDEKGEQKQKQEQVQDVMLGRQG-ERMGLTGEPEGLNDGEWEQEDMERKAQGQ 317
Query: 476 G 476
G
Sbjct: 318 G 318
>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
Length = 957
Score = 38.5 bits (88), Expect = 0.024
Identities = 77/291 (26%), Positives = 104/291 (35%), Gaps = 52/291 (17%)
Query: 306 DQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGK----------DVSRQTREADGE 355
D L IDD QQ + HP G +++ GQ GK DV + D E
Sbjct: 360 DVTLYIDD-----QQIENKPLHPVLG-ILINGQTQIGKYSGKEETVQFDVQKLRIYCDPE 413
Query: 356 QNPKEEAPR--GTGGEV--GLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQ 411
QN +E A G GE G G A P K GP+ P L G G+
Sbjct: 414 QNNRETACEIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGL----PGNPGYP 469
Query: 412 DDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQ 471
+ G + +P G Q A P +QG L PG + R
Sbjct: 470 G----QPGQDGKP--GYQGIAGTPGVPGSPGIQGARGL----------PGYKGEPGRDGD 513
Query: 472 AHHQGF-----VDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQ----PQAGGGRGWEGR 522
+G + G PGS+ + SP ++ G+ P G G GR
Sbjct: 514 KGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGR 573
Query: 523 GAGRWARPGPGWDGGARAGTQGLP-LPGTEAEPGALGCSLSRGPVPRQGSL 572
PG+ G AG+ G P GT EPG G +RG + ++G +
Sbjct: 574 HGKDGLMGSPGFKG--EAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEI 622
>gi|169214011 PREDICTED: hypothetical protein [Homo sapiens]
Length = 186
Score = 38.1 bits (87), Expect = 0.032
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
Query: 500 PLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARAG--TQGLPLPGTEAEPGAL 557
P R W +++ + G GRG RG GR +P G GG AG T + LP P
Sbjct: 103 PRGRGGW-EVRHRPGWGRGLHRRGLGRAEQPERGRAGGPGAGPRTPPMTLPSPPTLPAQD 161
Query: 558 GCSLSRGPVPRQGSLLSA 575
G +RGP P + L+A
Sbjct: 162 GKKEARGPEPPLETPLAA 179
>gi|239756028 PREDICTED: hypothetical protein [Homo sapiens]
Length = 255
Score = 38.1 bits (87), Expect = 0.032
Identities = 33/109 (30%), Positives = 40/109 (36%), Gaps = 16/109 (14%)
Query: 466 EERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGRGWEGRGAG 525
EER + G G +A +W PP P + +A GGR W GRGAG
Sbjct: 12 EERGASPPGIGGPKSQWGKSGWFSIAASWRVPPPPAMGVL------KARGGRAWGGRGAG 65
Query: 526 RWARP----------GPGWDGGARAGTQGLPLPGTEAEPGALGCSLSRG 564
+ P GP GG R LP A P G S+G
Sbjct: 66 SQSLPRGGASARCDGGPKSQGGKRGWLSVPSLPRGGASPQCDGGPKSQG 114
>gi|113428768 PREDICTED: hypothetical protein [Homo sapiens]
Length = 186
Score = 38.1 bits (87), Expect = 0.032
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
Query: 500 PLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARAG--TQGLPLPGTEAEPGAL 557
P R W +++ + G GRG RG GR +P G GG AG T + LP P
Sbjct: 103 PRGRGGW-EVRHRPGWGRGLHRRGLGRAEQPERGRAGGPGAGPRTPPMTLPSPPTLPAQD 161
Query: 558 GCSLSRGPVPRQGSLLSA 575
G +RGP P + L+A
Sbjct: 162 GKKEARGPEPPLETPLAA 179
>gi|113428351 PREDICTED: hypothetical protein [Homo sapiens]
Length = 186
Score = 38.1 bits (87), Expect = 0.032
Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
Query: 500 PLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARAG--TQGLPLPGTEAEPGAL 557
P R W +++ + G GRG RG GR +P G GG AG T + LP P
Sbjct: 103 PRGRGGW-EVRHRPGWGRGLHRRGLGRAEQPERGRAGGPGAGPRTPPMTLPSPPTLPAQD 161
Query: 558 GCSLSRGPVPRQGSLLSA 575
G +RGP P + L+A
Sbjct: 162 GKKEARGPEPPLETPLAA 179
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 37.4 bits (85), Expect = 0.054
Identities = 70/244 (28%), Positives = 84/244 (34%), Gaps = 29/244 (11%)
Query: 330 PGPVVLPGQEVEGKDVSRQTREADGEQNPKE-EAPRGTGGEVGLHHT-GKHEAEEAQGPQ 387
PGP G+ G S+ A GE P + P G GE G G+ GP
Sbjct: 427 PGPKGNSGEP--GAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPP 484
Query: 388 KEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVE 447
E GP F G G AG + + G +A RP +G+
Sbjct: 485 GERG-GPGSRGFPGA--DGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLT 541
Query: 448 ALAAA-GWDMALGP-GPWEQEERQSQ-----AHHQGFVDGHPGSQARLWLALTWDSPPAP 500
+ G D GP GP Q+ R A Q V G PG + P
Sbjct: 542 GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAA------GEPGKA 595
Query: 501 LQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA--GTQGLP----LPGTEAEP 554
+R V G P A G G +G AG PGP G R G G P LPG P
Sbjct: 596 GERGVPGP--PGAVGPAGKDGE-AGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPP 652
Query: 555 GALG 558
G G
Sbjct: 653 GEAG 656
Score = 33.1 bits (74), Expect = 1.0
Identities = 71/237 (29%), Positives = 86/237 (36%), Gaps = 44/237 (18%)
Query: 358 PKEEAPRGTGGEVGLHHT-------GKHEAEEAQGPQKEEYLGPQQAP-FLGVLH-KGEA 408
P + PRG GE G G A A GP GP P F G + KGEA
Sbjct: 298 PGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPT--GPAGPPGFPGAVGAKGEA 355
Query: 409 GHQ-----DDGEHKRGDNARPSH-GLQDDAPRPRAVTQVVVQGVEAL----AAAGWDMAL 458
G Q + + RG+ P G A P A Q +G A G+ A
Sbjct: 356 GPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415
Query: 459 GP-GPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSPPAPLQRSVWGQLQPQAGGGR 517
GP GP + G G PGS+ P P+ G P G
Sbjct: 416 GPSGPQGPGGPPGPKGNSG-EPGAPGSKGDTGAK----GEPGPV-----GVQGPP--GPA 463
Query: 518 GWEGRGAGRWARPGP-GWDG--GARAGTQGLPLPGTEAEPGALGCSLSRGPVPRQGS 571
G EG+ R PGP G G G R G PG+ PGA G + +GP +GS
Sbjct: 464 GEEGKRGAR-GEPGPTGLPGPPGERGG------PGSRGFPGADGVAGPKGPAGERGS 513
Score = 32.7 bits (73), Expect = 1.3
Identities = 91/364 (25%), Positives = 109/364 (29%), Gaps = 77/364 (21%)
Query: 223 PHHPYGNGGGCGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGG 282
P P G G GE + P + +G PG + +D G G
Sbjct: 282 PAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDG---------ATGAAG 332
Query: 283 GHGPACAA--VALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHP-----APGPVVL 335
GP A A+ G P + G Q E P A GP
Sbjct: 333 PPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSE-----GPQGVRGEPGPPGPAGAAGPAGN 387
Query: 336 PGQE-------------VEGKDVSRQTREADGEQNPK-EEAPRGTGGEVGLHHT-GKHEA 380
PG + + G R G Q P P+G GE G + G A
Sbjct: 388 PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA 447
Query: 381 EEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAPRPRAVTQ 440
+ GP +G Q P G AG E KRG P P R
Sbjct: 448 KGEPGP-----VGVQGPP-------GPAGE----EGKRGARGEPGPTGLPGPPGERG--- 488
Query: 441 VVVQGVEALAAAGWDMALGP-GPWEQEERQSQAHHQGFVD--GHPGSQARLWLALTWDSP 497
G + G D GP GP + A +G G PG SP
Sbjct: 489 ----GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSP 544
Query: 498 PAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGAR--AGTQGLPLP-GTEAEP 554
+P G P AG+ RPGP GAR AG G P P G EP
Sbjct: 545 GSPGPDGKTGPPGP------------AGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEP 592
Query: 555 GALG 558
G G
Sbjct: 593 GKAG 596
Score = 31.2 bits (69), Expect = 3.9
Identities = 62/248 (25%), Positives = 78/248 (31%), Gaps = 20/248 (8%)
Query: 330 PGPVVLPGQEVEGKDVSRQTREADGEQNPK----EEAPRGTGGEVGLHHTGKHEAEEAQG 385
PGP G GKD + G P E+ P G+ G GL E +
Sbjct: 601 PGPPGAVGPA--GKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGK- 657
Query: 386 PQKEEYLGPQQAPFLGVLH-----KGEAGHQDDG--EHKRGDNARPSH-GLQDDAPRPRA 437
P ++ G AP GE G Q RG N P + G + DA P A
Sbjct: 658 PGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGA 717
Query: 438 VTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALTWDSP 497
G++ + L PGP + + A +G DG PG L P
Sbjct: 718 PGSQGAPGLQGMPGERGAAGL-PGP---KGDRGDAGPKG-ADGSPGKDGVRGLTGPIGPP 772
Query: 498 PAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARAGTQGLPLPGTEAEPGAL 557
G+ P G G PGP G PG + EPG
Sbjct: 773 GPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDA 832
Query: 558 GCSLSRGP 565
G GP
Sbjct: 833 GAKGDAGP 840
Score = 30.8 bits (68), Expect = 5.1
Identities = 72/267 (26%), Positives = 90/267 (33%), Gaps = 48/267 (17%)
Query: 330 PGPVVLPGQEVEGKDVSRQTREADGEQNPK-EEAPRGTGGEVGLHHTGKHEAEEAQGPQK 388
PGP PG+ + + + R GE+ P + RG G GL H K
Sbjct: 223 PGP---PGKNGDDGEAGKPGRP--GERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAK 277
Query: 389 EEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSH----GLQDDAPRPRAVTQVVVQ 444
+ GP KGE G G+N P GL + RP A +
Sbjct: 278 GD-AGPAGP-------KGEPGSP-------GENGAPGQMGPRGLPGERGRPGAPGPAGAR 322
Query: 445 GVE-ALAAAGWDMALGP-GP-------------WEQEERQSQAHHQGFVDGHPGSQARLW 489
G + A AAG GP GP Q R S+ QG V G PG
Sbjct: 323 GNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGP-QG-VRGEPGPPGPAG 380
Query: 490 LALTWDSPPAPLQRSVWGQL-QPQAGGGRGWEG-RGA----GRWARPGPGWDGGARAGTQ 543
A +P A Q G P G G+ G RG G PGP + G
Sbjct: 381 AAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPG 440
Query: 544 GLPLPGTEAEPGALGCSLSRGPVPRQG 570
G + EPG +G GP +G
Sbjct: 441 SKGDTGAKGEPGPVGVQGPPGPAGEEG 467
Score = 30.4 bits (67), Expect = 6.6
Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 13/78 (16%)
Query: 497 PPAPLQRSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGGARA--GTQGLP-------L 547
PP P + G PQ G++ + G + PGP G R G G P
Sbjct: 149 PPGP--PGLGGNFAPQLS--YGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGP 204
Query: 548 PGTEAEPGALGCSLSRGP 565
PG EPGA G RGP
Sbjct: 205 PGEPGEPGASGPMGPRGP 222
>gi|122937233 discs, large (Drosophila) homolog-associated protein 3
[Homo sapiens]
Length = 979
Score = 37.0 bits (84), Expect = 0.071
Identities = 54/229 (23%), Positives = 79/229 (34%), Gaps = 41/229 (17%)
Query: 175 AGLGHLGDLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAV-------SIHDDPHHPY 227
AGLGH+ G + EGP +G EG + GG+ + D HP
Sbjct: 52 AGLGHISPEGP-LSLSEGPSVGPEGGPAGAGVGGGSSTFPRMYPGQGPFDTCEDCVGHPQ 110
Query: 228 GNGGGCGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPA 287
G G P L P L+ + +Q D H + G G GPA
Sbjct: 111 GKGA--------PRLPPTLL---------DQFEKQLPVQQDGFHTLPYQRGPAGAGPGPA 153
Query: 288 CAAVALRAALATAPNQGDDQPLCIDDDLYQGQQ---QSHSEDHPAPGPVVLPGQEVEGKD 344
TAP + P I ++ Q+ +SHS + APG G + EG+
Sbjct: 154 -------PGTGTAPEPRSESPSRIRHLVHSVQKLFAKSHSLE--APGKRDYNGPKAEGRG 204
Query: 345 VSRQTREADGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQKEEYLG 393
S D P P + HH H++ + + ++ G
Sbjct: 205 GS----GGDSYPGPGSGGPHTSHHHHHHHHHHHHQSRHGKRSKSKDRKG 249
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 37.0 bits (84), Expect = 0.071
Identities = 73/320 (22%), Positives = 102/320 (31%), Gaps = 57/320 (17%)
Query: 251 QGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQGDDQPLC 310
+GGPGP H + GDG G GP A R P +D
Sbjct: 1047 RGGPGPPFPPD---------HREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFR 1097
Query: 311 --IDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRGT-- 366
++ +G H P G PG E G + + E RGT
Sbjct: 1098 GRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPR 1157
Query: 367 GGEVGLHHTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSH 426
GG GL T E +G +K + + P GH+ + R D+ P H
Sbjct: 1158 GGRKGLLPT-PDEFPRFEGGRKPDSWDGNREP--------GPGHEHFRDTPRPDH--PPH 1206
Query: 427 GLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQA------HHQGFVDG 480
A R R+ + +QG++ + GP E R+ +A G G
Sbjct: 1207 DGHSPASRERSSS---LQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRG 1263
Query: 481 HPGSQARLWLALTWDSPPAPLQRSVWGQLQ-----------PQAGGGRGWEGRGAGRWAR 529
PG R+ P + S+ G+ P G GR W R
Sbjct: 1264 GPGPAQRV--------PKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGR 1315
Query: 530 -----PGPGWDGGARAGTQG 544
GP G +R G +G
Sbjct: 1316 GSNMNSGPPRRGASRGGGRG 1335
Score = 30.4 bits (67), Expect = 6.6
Identities = 69/296 (23%), Positives = 98/296 (33%), Gaps = 46/296 (15%)
Query: 191 EGPGIGGEGDGQRGVI-PGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDPM--LTPALV 247
+GP + G G +G + P G + D H P G + H P L P
Sbjct: 638 QGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM-----QRHPGPHGPLGP--- 689
Query: 248 AATQGGPGPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQGDDQ 307
QG PGPQ + Q H + G G GP + + T QG
Sbjct: 690 ---QGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQ-GHLGPQGPPGTQGMQGPPG 745
Query: 308 PLCIDDDLYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRGTG 367
P + QG H PG + G +G + R G P+E
Sbjct: 746 PRGM-----QGPPHPHG-IQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQ 799
Query: 368 GEV---------GLHHTG---KHEAEEAQGPQKEEYL--GPQQAPFLGVLH--KGEAGHQ 411
G + G H G H +E +GPQ+ + P Q LG +G G Q
Sbjct: 800 GMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQ 859
Query: 412 DDGEHKRGDNARPSHGLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEE 467
+G P G P P+ + A G + GP P++Q++
Sbjct: 860 SQQGPPQGSLGPPPQGGMQGPPGPQG---------QQNPARGPHPSQGPIPFQQQK 906
Score = 30.4 bits (67), Expect = 6.6
Identities = 31/123 (25%), Positives = 46/123 (37%), Gaps = 20/123 (16%)
Query: 317 QGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTG 376
QGQQ HP+ GP+ P Q+ + DG + P + + TG + G
Sbjct: 884 QGQQNPARGPHPSQGPI--PFQQ------QKTPLLGDGPRAPFNQEGQSTGPPPLIPGLG 935
Query: 377 KHEAE---------EAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHG 427
+ A+ + GP K + GP P + E H+ G + G P G
Sbjct: 936 QQGAQGRIPPLNPGQGPGPNKGDSRGP---PNHHMGPMSERRHEQSGGPEHGPERGPFRG 992
Query: 428 LQD 430
QD
Sbjct: 993 GQD 995
>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
Length = 695
Score = 36.6 bits (83), Expect = 0.092
Identities = 29/116 (25%), Positives = 49/116 (42%), Gaps = 8/116 (6%)
Query: 326 DHPAPGPVVLPGQEVEGK--DVSRQTREADGEQNPKEEA--PRGTGGEVGLHHTGKHEAE 381
+ P V++PG + + + A GE+ E+A P G G + G E
Sbjct: 459 EEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTE 518
Query: 382 EAQGPQKE----EYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAP 433
A+ Q E E PQ+ V+ + + H+++GE++ A P +D AP
Sbjct: 519 GAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAP 574
>gi|154146231 DMRT-like family A2 [Homo sapiens]
Length = 542
Score = 36.6 bits (83), Expect = 0.092
Identities = 82/319 (25%), Positives = 106/319 (33%), Gaps = 92/319 (28%)
Query: 279 GTGGGHGPACAAVA------------LRAALATAPNQGDDQPLCIDDDLYQGQQQSHSED 326
GTGGG A + A L+A +P +PL D G S E
Sbjct: 175 GTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLS-PDGADSGPGTSSPEV 233
Query: 327 HPAPGPVVLPGQEVEGKDVSRQTREADG-------------EQNPKEEAPRGTGGEVGLH 373
P G G+ G ++R ++EA G E +P +P G+ E G
Sbjct: 234 RPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGS--ESG-S 290
Query: 374 HTGKHEAEEAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSHGLQDDAP 433
K E E A P GP+Q L +L + GH+
Sbjct: 291 EADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHR---------------------- 328
Query: 434 RPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDGHPGSQARLWLALT 493
R V ++V+QG G D+ Q Q HH+G G A L
Sbjct: 329 --RGVLELVLQG------CGGDVV-------QAIEQVLNHHRG------GLAAGL----- 362
Query: 494 WDSPPAPLQRSVWGQLQPQAGGGRGWEGR----GAGRWARPGPGWDGGARAGTQGLP--- 546
P AP ++ G A W R A A GPG +AG P
Sbjct: 363 --GPAAPPDKAAVG---AAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHR 417
Query: 547 --LPGTEAEPGALGCSLSR 563
L G A PGALG SR
Sbjct: 418 PLLAGAMA-PGALGSLSSR 435
Score = 30.8 bits (68), Expect = 5.1
Identities = 39/138 (28%), Positives = 51/138 (36%), Gaps = 14/138 (10%)
Query: 182 DLGDDVEEDEGPGIGGEGDGQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDPM 241
+ G GPG GGE D P G+ A + G GGG G + P
Sbjct: 258 EAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTP- 316
Query: 242 LTPALVAATQGGPGPQEGT-----QQQQHDVDECHDKV--HVGDGTGGGHGPACAAVALR 294
L T+ PG + G Q DV + ++V H G G GP AA +
Sbjct: 317 ----LDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGP--AAPPDK 370
Query: 295 AALATAPNQGDDQPLCID 312
AA+ A D P +D
Sbjct: 371 AAVGAAAAADDAWPSRVD 388
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 36.2 bits (82), Expect = 0.12
Identities = 56/282 (19%), Positives = 90/282 (31%), Gaps = 65/282 (23%)
Query: 178 GHLGDLGDDVEEDEG-------PGIGGEGD-------------GQRGVIPGGTVVLLVAV 217
GH G G + EG + G G G+ G G + L V
Sbjct: 413 GHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQV 472
Query: 218 SIHDDPHHPYGNGGGCGEEHKDPMLTPALVAATQGGPGPQEGTQQQQHDVDECHDKVHVG 277
S H+ P +G G G ++G+ +Q H G
Sbjct: 473 STHEQPDSAHGRTGT--------------------STGGRQGSHHEQARDSSRHSASQEG 512
Query: 278 DGTGGGHGPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQQQSHSEDHPAPGPVVLPG 337
T GH + + QG ++ + G SH+ G
Sbjct: 513 QDTIRGHPGS----------SRGGRQGSHHEQSVNRSGHSGSHHSHTTSQ---GRSDASH 559
Query: 338 QEVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHHTGKHEAEEAQGPQ--KEEYLGPQ 395
+ + SRQTR +E++ GT HH +A+ ++ Q + + GP+
Sbjct: 560 GQSGSRSASRQTRN-------EEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPR 612
Query: 396 QAPFLGVLHKGEA---GHQDDGEHKRGDNARPSHGLQDDAPR 434
+ G ++ GH +D E G +R HG + R
Sbjct: 613 TSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSR 654
Score = 33.5 bits (75), Expect = 0.78
Identities = 64/300 (21%), Positives = 92/300 (30%), Gaps = 76/300 (25%)
Query: 201 GQRGVIPGGTVVLLVAVSIHDDPHHPYGNGGGCGEEHKDPMLTPALVAATQGGPGPQEGT 260
GQ G G + L VS H+ +G A + GG ++G+
Sbjct: 2078 GQSGESSGRSGSFLYQVSTHEQSESTHGQS-----------------APSTGG---RQGS 2117
Query: 261 QQQQHDVDECHDKVHVGDGTGGGH-GPACAAVALRAALATAPNQGDDQPLCIDDDLYQGQ 319
Q H G T GH GP+ QG Q +D + G
Sbjct: 2118 HYDQAQDSSRHSASQEGQDTIRGHPGPSRGG-----------RQGSHQEQSVDRSGHSGS 2166
Query: 320 QQSHSEDHPAPGPVVLPGQEVEGKDVSRQ---TREADGEQNPKEEAPRGTGGEVGLHHTG 376
SH+ D SR +R A + KE++ G+ HH
Sbjct: 2167 HHSHTTSQGR-------------SDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEA 2213
Query: 377 KHEAE----------EAQGPQKEEYLGPQQAPFLGVLHKGEAGHQDDGEHKRGDNARPSH 426
A+ ++ GP+ G + GH +D E + G +R H
Sbjct: 2214 SSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQ-----DSDSEGHSEDSERRSGSASRNHH 2268
Query: 427 GLQDDAPRPRAVTQVVVQGVEALAAAGWDMALGPGPWEQEERQSQAHHQGFVDGHPGSQA 486
G + R G + D A G G + RQS HH + G QA
Sbjct: 2269 GSAQEQSR---------DGSRHPRSHHEDRA-GHGHSAESSRQSGTHH---AENSSGGQA 2315
Score = 30.8 bits (68), Expect = 5.1
Identities = 41/193 (21%), Positives = 68/193 (35%), Gaps = 30/193 (15%)
Query: 255 GPQEGTQQQQHDVDECHDKVHVGDGTGGGHGPACAAVALRAALATAPNQGDDQPLCIDDD 314
G ++G+ +Q H G T GH + ++ QG +D
Sbjct: 2436 GGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGS----------SSGGRQGSHYEQLVDRS 2485
Query: 315 LYQGQQQSHSEDHPAPGPVVLPGQEVEGKDVSRQTREADGEQNPKEEAPRGTGGEVGLHH 374
+ G SH+ G + SRQTR E++ G+ HH
Sbjct: 2486 GHSGSHHSHTTSQ---GRSDASHGHSGSRSASRQTRN-------DEQSGDGSRHSGSRHH 2535
Query: 375 TGKHEAEEAQGPQ--KEEYLGPQQAPFLGVLHKGEA---GHQDDGEHKRGDNARPSHG-- 427
A+ + Q + + GP+ + G ++ GH +D E G +R HG
Sbjct: 2536 EASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSA 2595
Query: 428 ---LQDDAPRPRA 437
L+D + PR+
Sbjct: 2596 QEQLRDGSRHPRS 2608
>gi|239751449 PREDICTED: hypothetical protein XP_002347867 [Homo
sapiens]
Length = 315
Score = 36.2 bits (82), Expect = 0.12
Identities = 56/209 (26%), Positives = 73/209 (34%), Gaps = 40/209 (19%)
Query: 440 QVVVQGVEALAAAGWDMALGPGPWE-QEERQSQAHHQGFVDGHPGSQARLWLALTWDSPP 498
+V G LA G P P+ + ER S+ H G PGS+ R + D P
Sbjct: 42 EVAPAGGSPLAVGGAFRVSSPRPFPPRPERPSRRHRAGCGAHGPGSRGRERRRGSRDPPA 101
Query: 499 APLQ------RSVWGQLQPQAGGGRGWEGRGAGRWARPGPGWDGG-----------ARAG 541
P+ RS G QP +G G A A P P WD +
Sbjct: 102 GPVARARARGRSAPGSAQPASGAA----GPAAAPEAAP-PAWDPATLPPSRKRNSLGSSP 156
Query: 542 TQGLPLPGTEAEPGALGCSLSRGPVPRQGSLLSARVGWSLHHRYIT----SIQGANRAPA 597
+ L A G G S+ R V +L A+V W+ HR+ S+Q A P
Sbjct: 157 LHPVRLGRVRAHAGPAGTSILR--VAPHPALPGAQVHWAGRHRWAARRGKSLQSAWWGPG 214
Query: 598 ALQVRALRLHRNKACP---ALPAPTHLQA 623
RN P PAP +A
Sbjct: 215 G--------RRNSISPGRTTFPAPPTQEA 235
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.136 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,550,072
Number of Sequences: 37866
Number of extensions: 2500425
Number of successful extensions: 10342
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 290
Number of HSP's that attempted gapping in prelim test: 9414
Number of HSP's gapped (non-prelim): 1176
length of query: 783
length of database: 18,247,518
effective HSP length: 110
effective length of query: 673
effective length of database: 14,082,258
effective search space: 9477359634
effective search space used: 9477359634
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.