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Search of human proteins with 239751186
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]
(2240 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens] 4536 0.0
gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens] 3922 0.0
gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens] 3922 0.0
gi|149944548 neurobeachin-like 2 [Homo sapiens] 107 1e-22
gi|148233596 LPS-responsive vesicle trafficking, beach and ancho... 105 5e-22
gi|31543297 neutral sphingomyelinase (N-SMase) activation associ... 104 9e-22
gi|221625547 neutral sphingomyelinase (N-SMase) activation assoc... 104 9e-22
gi|62422577 neurobeachin [Homo sapiens] 103 1e-21
gi|224451124 neurobeachin-like 1 isoform 3 [Homo sapiens] 102 4e-21
gi|149944613 neurobeachin-like 1 isoform 1 [Homo sapiens] 102 4e-21
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 100 2e-20
gi|154240744 neurobeachin-like 1 isoform 2 [Homo sapiens] 96 4e-19
gi|191252801 WDFY family member 4 [Homo sapiens] 90 3e-17
gi|54292123 lysosomal trafficking regulator [Homo sapiens] 69 5e-11
gi|89886480 zinedin isoform 2 [Homo sapiens] 62 5e-09
gi|89886477 zinedin isoform 1 [Homo sapiens] 62 5e-09
gi|26665869 WD repeat domain 51B [Homo sapiens] 61 1e-08
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 59 5e-08
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 59 5e-08
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 59 5e-08
gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens] 56 5e-07
gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens] 56 5e-07
gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens] 56 5e-07
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 55 8e-07
gi|157785645 SPEG complex locus [Homo sapiens] 52 9e-06
gi|38569484 kinesin family member 21A [Homo sapiens] 51 1e-05
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 49 4e-05
gi|16554629 WD repeat domain 5 [Homo sapiens] 49 7e-05
gi|16554627 WD repeat domain 5 [Homo sapiens] 49 7e-05
gi|239745807 PREDICTED: keratin associated protein 4-9 [Homo sap... 49 7e-05
>gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 2240
Score = 4536 bits (11766), Expect = 0.0
Identities = 2240/2240 (100%), Positives = 2240/2240 (100%)
Query: 1 MSELCSKFQAPPPQFQRMNQQEKPGPAAWPREGAGGVAGSGDRQSTSSPPARGVQTLPRL 60
MSELCSKFQAPPPQFQRMNQQEKPGPAAWPREGAGGVAGSGDRQSTSSPPARGVQTLPRL
Sbjct: 1 MSELCSKFQAPPPQFQRMNQQEKPGPAAWPREGAGGVAGSGDRQSTSSPPARGVQTLPRL 60
Query: 61 DGRPLYPQTGGRRLTPTWCWVWGLLHEGEQITASAPHGRRRCLFSAPSTHRLQAPISWRR 120
DGRPLYPQTGGRRLTPTWCWVWGLLHEGEQITASAPHGRRRCLFSAPSTHRLQAPISWRR
Sbjct: 61 DGRPLYPQTGGRRLTPTWCWVWGLLHEGEQITASAPHGRRRCLFSAPSTHRLQAPISWRR 120
Query: 121 RDARAANARPGANHRPLLGNVAPPTRGPTGPRPGPASPGALALIALRVSDPLRKALRQTR 180
RDARAANARPGANHRPLLGNVAPPTRGPTGPRPGPASPGALALIALRVSDPLRKALRQTR
Sbjct: 121 RDARAANARPGANHRPLLGNVAPPTRGPTGPRPGPASPGALALIALRVSDPLRKALRQTR 180
Query: 181 VLKSRRKPRRLRLQCMLVRVVLSLTPSFPEPSALSDPSRWSPVLAPGSLCPAAPGAQDPR 240
VLKSRRKPRRLRLQCMLVRVVLSLTPSFPEPSALSDPSRWSPVLAPGSLCPAAPGAQDPR
Sbjct: 181 VLKSRRKPRRLRLQCMLVRVVLSLTPSFPEPSALSDPSRWSPVLAPGSLCPAAPGAQDPR 240
Query: 241 RGKRAPRPPLRRRRLPAAASAPAPVPRPSQPRRPGTPEAVASRAVAGLSPALPPGGLEEM 300
RGKRAPRPPLRRRRLPAAASAPAPVPRPSQPRRPGTPEAVASRAVAGLSPALPPGGLEEM
Sbjct: 241 RGKRAPRPPLRRRRLPAAASAPAPVPRPSQPRRPGTPEAVASRAVAGLSPALPPGGLEEM 300
Query: 301 AQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPAR 360
AQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPAR
Sbjct: 301 AQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPAR 360
Query: 361 WLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLGG 420
WLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLGG
Sbjct: 361 WLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLGG 420
Query: 421 GLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQAL 480
GLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQAL
Sbjct: 421 GLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQAL 480
Query: 481 QRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQFS 540
QRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQFS
Sbjct: 481 QRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQFS 540
Query: 541 LHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELRL 600
LHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELRL
Sbjct: 541 LHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELRL 600
Query: 601 DLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNFH 660
DLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNFH
Sbjct: 601 DLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNFH 660
Query: 661 YLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMTR 720
YLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMTR
Sbjct: 661 YLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMTR 720
Query: 721 QAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASME 780
QAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASME
Sbjct: 721 QAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASME 780
Query: 781 RMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRDL 840
RMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRDL
Sbjct: 781 RMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRDL 840
Query: 841 HHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAPE 900
HHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAPE
Sbjct: 841 HHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAPE 900
Query: 901 PPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLEQ 960
PPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLEQ
Sbjct: 901 PPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLEQ 960
Query: 961 ATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRILL 1020
ATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRILL
Sbjct: 961 ATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRILL 1020
Query: 1021 PEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAEM 1080
PEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAEM
Sbjct: 1021 PEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAEM 1080
Query: 1081 VFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERGK 1140
VFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERGK
Sbjct: 1081 VFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERGK 1140
Query: 1141 LDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGREL 1200
LDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGREL
Sbjct: 1141 LDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGREL 1200
Query: 1201 VFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANKY 1260
VFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANKY
Sbjct: 1201 VFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANKY 1260
Query: 1261 LLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQEE 1320
LLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQEE
Sbjct: 1261 LLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQEE 1320
Query: 1321 SKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLPE 1380
SKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLPE
Sbjct: 1321 SKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLPE 1380
Query: 1381 TEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSGD 1440
TEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSGD
Sbjct: 1381 TEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSGD 1440
Query: 1441 SSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGGD 1500
SSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGGD
Sbjct: 1441 SSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGGD 1500
Query: 1501 GEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGPT 1560
GEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGPT
Sbjct: 1501 GEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGPT 1560
Query: 1561 RQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYISY 1620
RQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYISY
Sbjct: 1561 RQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYISY 1620
Query: 1621 LVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFLT 1680
LVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFLT
Sbjct: 1621 LVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFLT 1680
Query: 1681 SLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQQ 1740
SLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQQ
Sbjct: 1681 SLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQQ 1740
Query: 1741 DLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDIIR 1800
DLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDIIR
Sbjct: 1741 DLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDIIR 1800
Query: 1801 KIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFGS 1860
KIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFGS
Sbjct: 1801 KIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFGS 1860
Query: 1861 VLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAYW 1920
VLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAYW
Sbjct: 1861 VLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAYW 1920
Query: 1921 QYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG 1980
QYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG
Sbjct: 1921 QYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG 1980
Query: 1981 DGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRVP 2040
DGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRVP
Sbjct: 1981 DGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRVP 2040
Query: 2041 LTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSV 2100
LTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSV
Sbjct: 2041 LTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSV 2100
Query: 2101 VAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQKP 2160
VAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQKP
Sbjct: 2101 VAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQKP 2160
Query: 2161 THHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLAL 2220
THHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLAL
Sbjct: 2161 THHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLAL 2220
Query: 2221 LPTKRHLLLGSDNGVIRLLA 2240
LPTKRHLLLGSDNGVIRLLA
Sbjct: 2221 LPTKRHLLLGSDNGVIRLLA 2240
>gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 1941
Score = 3922 bits (10170), Expect = 0.0
Identities = 1941/1941 (100%), Positives = 1941/1941 (100%)
Query: 300 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 359
MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA
Sbjct: 1 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60
Query: 360 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 419
RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG
Sbjct: 61 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120
Query: 420 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 479
GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA
Sbjct: 121 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180
Query: 480 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 539
LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF
Sbjct: 181 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240
Query: 540 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 599
SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR
Sbjct: 241 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300
Query: 600 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 659
LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF
Sbjct: 301 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360
Query: 660 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 719
HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT
Sbjct: 361 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420
Query: 720 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 779
RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM
Sbjct: 421 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480
Query: 780 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 839
ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD
Sbjct: 481 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540
Query: 840 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 899
LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP
Sbjct: 541 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600
Query: 900 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 959
EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE
Sbjct: 601 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660
Query: 960 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 1019
QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL
Sbjct: 661 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720
Query: 1020 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 1079
LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE
Sbjct: 721 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780
Query: 1080 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 1139
MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG
Sbjct: 781 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840
Query: 1140 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 1199
KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE
Sbjct: 841 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900
Query: 1200 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 1259
LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK
Sbjct: 901 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960
Query: 1260 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1319
YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE
Sbjct: 961 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020
Query: 1320 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1379
ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP
Sbjct: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080
Query: 1380 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1439
ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG
Sbjct: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140
Query: 1440 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1499
DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG
Sbjct: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200
Query: 1500 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1559
DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP
Sbjct: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260
Query: 1560 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1619
TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS
Sbjct: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320
Query: 1620 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1679
YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL
Sbjct: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380
Query: 1680 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1739
TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ
Sbjct: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440
Query: 1740 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1799
QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII
Sbjct: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500
Query: 1800 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1859
RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG
Sbjct: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560
Query: 1860 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1919
SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY
Sbjct: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620
Query: 1920 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1979
WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY
Sbjct: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680
Query: 1980 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 2039
GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV
Sbjct: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740
Query: 2040 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 2099
PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS
Sbjct: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800
Query: 2100 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 2159
VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK
Sbjct: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
Query: 2160 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 2219
PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA
Sbjct: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920
Query: 2220 LLPTKRHLLLGSDNGVIRLLA 2240
LLPTKRHLLLGSDNGVIRLLA
Sbjct: 1921 LLPTKRHLLLGSDNGVIRLLA 1941
>gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 1941
Score = 3922 bits (10170), Expect = 0.0
Identities = 1941/1941 (100%), Positives = 1941/1941 (100%)
Query: 300 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 359
MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA
Sbjct: 1 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60
Query: 360 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 419
RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG
Sbjct: 61 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120
Query: 420 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 479
GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA
Sbjct: 121 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180
Query: 480 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 539
LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF
Sbjct: 181 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240
Query: 540 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 599
SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR
Sbjct: 241 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300
Query: 600 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 659
LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF
Sbjct: 301 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360
Query: 660 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 719
HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT
Sbjct: 361 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420
Query: 720 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 779
RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM
Sbjct: 421 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480
Query: 780 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 839
ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD
Sbjct: 481 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540
Query: 840 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 899
LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP
Sbjct: 541 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600
Query: 900 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 959
EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE
Sbjct: 601 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660
Query: 960 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 1019
QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL
Sbjct: 661 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720
Query: 1020 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 1079
LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE
Sbjct: 721 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780
Query: 1080 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 1139
MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG
Sbjct: 781 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840
Query: 1140 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 1199
KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE
Sbjct: 841 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900
Query: 1200 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 1259
LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK
Sbjct: 901 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960
Query: 1260 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1319
YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE
Sbjct: 961 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020
Query: 1320 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1379
ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP
Sbjct: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080
Query: 1380 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1439
ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG
Sbjct: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140
Query: 1440 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1499
DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG
Sbjct: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200
Query: 1500 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1559
DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP
Sbjct: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260
Query: 1560 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1619
TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS
Sbjct: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320
Query: 1620 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1679
YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL
Sbjct: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380
Query: 1680 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1739
TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ
Sbjct: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440
Query: 1740 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1799
QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII
Sbjct: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500
Query: 1800 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1859
RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG
Sbjct: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560
Query: 1860 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1919
SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY
Sbjct: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620
Query: 1920 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1979
WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY
Sbjct: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680
Query: 1980 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 2039
GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV
Sbjct: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740
Query: 2040 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 2099
PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS
Sbjct: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800
Query: 2100 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 2159
VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK
Sbjct: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
Query: 2160 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 2219
PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA
Sbjct: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920
Query: 2220 LLPTKRHLLLGSDNGVIRLLA 2240
LLPTKRHLLLGSDNGVIRLLA
Sbjct: 1921 LLPTKRHLLLGSDNGVIRLLA 1941
>gi|149944548 neurobeachin-like 2 [Homo sapiens]
Length = 2754
Score = 107 bits (267), Expect = 1e-22
Identities = 97/310 (31%), Positives = 131/310 (42%), Gaps = 68/310 (21%)
Query: 641 QEELRS--LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH----- 692
QE LR+ L WV ISNF YLMQLN +AGR D + +PV PWV+ D+ +P
Sbjct: 2056 QEMLRASGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPTLDLSN 2115
Query: 693 -GRFRDLRKSKFRLNKGDKQLDFTYEMTRQAFVA--GGAGGGEPPHVPHHISDVLSDITY 749
FRDL K +N QL R+ + + AG + H H S+ + Y
Sbjct: 2116 PAVFRDLSKPIGVVNPKHAQL------VREKYESFEDPAGTIDKFHYGTHYSNAAGVMHY 2169
Query: 750 YVYKARRTPRSVL-------CGH-----VRAQWEPH-EYPASMERMQNWTPDECIPEFYT 796
+ T V C V A W+ E PA ++ E IPEF+
Sbjct: 2170 LIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQARLESPADVK--------ELIPEFFY 2221
Query: 797 DPSIFRS-----------IHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWID 845
P + + + D+ +P W SS ++F+ HR LES VS LH WID
Sbjct: 2222 FPDFLENQNGFDLGCLQLTNEKVGDVVLPPWASSPEDFIQQHRQALESEYVSAHLHEWID 2281
Query: 846 LTFGYKLQGKEAVKEKNVCL-----------HLVDAHTHLASYGVV--------QLFDQP 886
L FGYK +G A + NV H+ D A G++ QL +P
Sbjct: 2282 LIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVTDERERKALEGIISNFGQTPCQLLKEP 2341
Query: 887 HPQRLAGAPA 896
HP RL+ A
Sbjct: 2342 HPTRLSAEEA 2351
Score = 32.7 bits (73), Expect = 4.1
Identities = 57/236 (24%), Positives = 84/236 (35%), Gaps = 38/236 (16%)
Query: 1879 GPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAYWQYEIGVSQQDAHFHFHQI 1938
GP P SGV G L D L SG +W + V+ Q+
Sbjct: 2452 GPWVPGSGVSGQALAVAPDGKLL----------FSGG---HWDGSLRVTALPRGKLLSQL 2498
Query: 1939 RLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYT--QHR 1996
H V C+A + + +SGS+D T +W L + G + AP+ V H
Sbjct: 2499 SC-----HLDVVTCLALDTCGIYLISGSRDTTCMVWRLLHQGGLSVGLAPKPVQVLYGHG 2553
Query: 1997 KSVFFVGQLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 2054
+V V VS DG V + G+ + + PL A P P +
Sbjct: 2554 AAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPLG--------ATFPGPIFHL 2605
Query: 2055 TMASSDS-TLRFVDCRKPGLQ-----HEFRLGGGLNPGLVRALAISPSGRSVVAGF 2104
+ S ++ +PG Q H + + G L L LA P+ +V F
Sbjct: 2606 ALGSEGQIVVQSSAWERPGAQVTYSLHLYSVNGKLRASL--PLAEQPTALTVTEDF 2659
>gi|148233596 LPS-responsive vesicle trafficking, beach and anchor
containing [Homo sapiens]
Length = 2863
Score = 105 bits (262), Expect = 5e-22
Identities = 93/287 (32%), Positives = 120/287 (41%), Gaps = 59/287 (20%)
Query: 651 WVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRDLRKSK 702
W H ISNF YLM LN +AGR D N +PV PWV+ D T P FRDL K
Sbjct: 2215 WQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPTN-FRDLSKPI 2273
Query: 703 FRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPH-HISDVLSDITYYV-YKARRTPRS 760
LN R AF A E VP H S ++ + + R P +
Sbjct: 2274 GALNP-----------KRAAFFAERYESWEDDQVPKFHYGTHYSTASFVLAWLLRIEPFT 2322
Query: 761 VLCGHVRAQWEPHEYPASMERMQNW------TPD--ECIPEFYTDPSIFRSIH------- 805
+++ H + W T D E IPEFY P +F + +
Sbjct: 2323 TYFLNLQGGKFDHADRTFSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVM 2382
Query: 806 ---PDMPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 862
+ D+++P W +S+EFV +R LES VS LH WIDL FGYK QG EAV+ N
Sbjct: 2383 DDGTVVSDVELPPWAKTSEEFVHINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALN 2442
Query: 863 VCLHLV-----------------DAHTHLASYGVV--QLFDQPHPQR 890
V +L + S+G QL +PHP R
Sbjct: 2443 VFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPR 2489
>gi|31543297 neutral sphingomyelinase (N-SMase) activation
associated factor isoform 1 [Homo sapiens]
Length = 917
Score = 104 bits (260), Expect = 9e-22
Identities = 87/286 (30%), Positives = 127/286 (44%), Gaps = 49/286 (17%)
Query: 646 SLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRD 697
S +L W G +SN+ YL+ LN LA R D + +PV PW++ D + P G FRD
Sbjct: 300 SYMLQWQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWIIHDYSSSELDLSNP-GTFRD 358
Query: 698 LRKSKFRLNKG--DKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKAR 755
L K LNK ++ L EM F+ G + P +V ++ + + + R
Sbjct: 359 LSKPVGALNKERLERLLTRYQEMPEPKFMYG-SHYSSPGYVLFYLVRIAPEYMLCLQNGR 417
Query: 756 RTPRSVLCGHVRAQWEPHEYPASMERMQNWTPDECIPEFYTDPSIF--RSIHPDM----- 808
+ + W+ A+ + E IPEFY D F S+ D+
Sbjct: 418 FDNADRMFNSIAETWKNCLDGATDFK-------ELIPEFYGDDVSFLVNSLKLDLGKRQG 470
Query: 809 ----PDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKNVC 864
D+++P W SS ++F+ + LES VS LH WIDL FGYK +G +AV NV
Sbjct: 471 GQMVDDVELPPWASSPEDFLQKSKDALESNYVSEHLHEWIDLIFGYKQKGSDAVGAHNVF 530
Query: 865 LHL-----VDAH------------THLASYGVV--QLFDQPHPQRL 891
L VD + T + +G QLF PHP+R+
Sbjct: 531 HPLTYEGGVDLNSIQDPDEKVAMLTQILEFGQTPKQLFVTPHPRRI 576
Score = 35.8 bits (81), Expect = 0.49
Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 14/154 (9%)
Query: 2013 SCDGAVHVWDPFTGKTLRT-------VEPLDSRVPLTAVAVMPAPHTSITMASSDSTLRF 2065
S D V VW + T + L+ V + ++ + A T + + + T+
Sbjct: 731 SWDSTVKVWSGVPAEMPGTKRHHFDLLAELEHDVSVDTIS-LNAASTLLVSGTKEGTVNI 789
Query: 2066 VDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPA 2125
D L H+ + G+V A SP R V++ + G + ++D +TG+++ +
Sbjct: 790 WDLTTATLMHQIPC----HSGIVCDTAFSPDSRHVLSTGTDGCLNVIDVQTGMLISSMTS 845
Query: 2126 HEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 2159
E + +G+ ++S S L VW L K
Sbjct: 846 DEPQ--RCFVWDGNSVLSGSQSGELLVWDLLGAK 877
>gi|221625547 neutral sphingomyelinase (N-SMase) activation
associated factor isoform 2 [Homo sapiens]
Length = 948
Score = 104 bits (260), Expect = 9e-22
Identities = 87/286 (30%), Positives = 127/286 (44%), Gaps = 49/286 (17%)
Query: 646 SLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRD 697
S +L W G +SN+ YL+ LN LA R D + +PV PW++ D + P G FRD
Sbjct: 331 SYMLQWQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWIIHDYSSSELDLSNP-GTFRD 389
Query: 698 LRKSKFRLNKG--DKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKAR 755
L K LNK ++ L EM F+ G + P +V ++ + + + R
Sbjct: 390 LSKPVGALNKERLERLLTRYQEMPEPKFMYG-SHYSSPGYVLFYLVRIAPEYMLCLQNGR 448
Query: 756 RTPRSVLCGHVRAQWEPHEYPASMERMQNWTPDECIPEFYTDPSIF--RSIHPDM----- 808
+ + W+ A+ + E IPEFY D F S+ D+
Sbjct: 449 FDNADRMFNSIAETWKNCLDGATDFK-------ELIPEFYGDDVSFLVNSLKLDLGKRQG 501
Query: 809 ----PDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKNVC 864
D+++P W SS ++F+ + LES VS LH WIDL FGYK +G +AV NV
Sbjct: 502 GQMVDDVELPPWASSPEDFLQKSKDALESNYVSEHLHEWIDLIFGYKQKGSDAVGAHNVF 561
Query: 865 LHL-----VDAH------------THLASYGVV--QLFDQPHPQRL 891
L VD + T + +G QLF PHP+R+
Sbjct: 562 HPLTYEGGVDLNSIQDPDEKVAMLTQILEFGQTPKQLFVTPHPRRI 607
Score = 35.8 bits (81), Expect = 0.49
Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 14/154 (9%)
Query: 2013 SCDGAVHVWDPFTGKTLRT-------VEPLDSRVPLTAVAVMPAPHTSITMASSDSTLRF 2065
S D V VW + T + L+ V + ++ + A T + + + T+
Sbjct: 762 SWDSTVKVWSGVPAEMPGTKRHHFDLLAELEHDVSVDTIS-LNAASTLLVSGTKEGTVNI 820
Query: 2066 VDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPA 2125
D L H+ + G+V A SP R V++ + G + ++D +TG+++ +
Sbjct: 821 WDLTTATLMHQIPC----HSGIVCDTAFSPDSRHVLSTGTDGCLNVIDVQTGMLISSMTS 876
Query: 2126 HEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 2159
E + +G+ ++S S L VW L K
Sbjct: 877 DEPQ--RCFVWDGNSVLSGSQSGELLVWDLLGAK 908
>gi|62422577 neurobeachin [Homo sapiens]
Length = 2946
Score = 103 bits (258), Expect = 1e-21
Identities = 96/299 (32%), Positives = 127/299 (42%), Gaps = 50/299 (16%)
Query: 651 WVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRDLRKSK 702
W ISNF YLM LN +AGR D N +PV PWV+ D T P G FRDL K
Sbjct: 2289 WQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLP-GNFRDLSKPI 2347
Query: 703 FRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVL 762
LN K+ F E + P H H S S +++ V T +
Sbjct: 2348 GALNP--KRAVFYAER----YETWEDDQSPPYHYNTHYSTATSTLSWLVRIEPFTTFFLN 2401
Query: 763 CGHVRAQWEPHEYPA---SMERMQNWTPD--ECIPEFYTDPSIF----------RSIHPD 807
+ + + S Q T D E IPEFY P +F R
Sbjct: 2402 ANDGKFDHPDRTFSSVARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNLGVREDEVV 2461
Query: 808 MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKNVCLHL 867
+ D+D+P W ++FV +R LES VS LH WIDL FGYK +G EAV+ NV +L
Sbjct: 2462 VNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYL 2521
Query: 868 -------VDAHT----------HLASYGVV--QLFDQPHPQRLAGAP-ALAPEPPLIPK 906
+D+ T + ++G QL +PHP R + P+ PL+ K
Sbjct: 2522 TYEGSVNLDSITDPVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFK 2580
>gi|224451124 neurobeachin-like 1 isoform 3 [Homo sapiens]
Length = 2694
Score = 102 bits (254), Expect = 4e-21
Identities = 88/294 (29%), Positives = 127/294 (43%), Gaps = 48/294 (16%)
Query: 647 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 699
L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL
Sbjct: 2003 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 2062
Query: 700 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 758
K +N K K + YE G + H H S+ + Y + T
Sbjct: 2063 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 2117
Query: 759 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 807
+ R A + H PA+ + + + D E IPEF+ P + +
Sbjct: 2118 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 2177
Query: 808 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 862
+ D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N
Sbjct: 2178 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 2237
Query: 863 VCLH-----------LVDAHTHLASYGVV--------QLFDQPHPQRLAGAPAL 897
V + L D A G++ QL +PHP RL+ A+
Sbjct: 2238 VFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAV 2291
>gi|149944613 neurobeachin-like 1 isoform 1 [Homo sapiens]
Length = 1404
Score = 102 bits (254), Expect = 4e-21
Identities = 88/294 (29%), Positives = 127/294 (43%), Gaps = 48/294 (16%)
Query: 647 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 699
L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL
Sbjct: 713 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 772
Query: 700 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 758
K +N K K + YE G + H H S+ + Y + T
Sbjct: 773 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 827
Query: 759 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 807
+ R A + H PA+ + + + D E IPEF+ P + +
Sbjct: 828 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 887
Query: 808 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 862
+ D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N
Sbjct: 888 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 947
Query: 863 VCLH-----------LVDAHTHLASYGVV--------QLFDQPHPQRLAGAPAL 897
V + L D A G++ QL +PHP RL+ A+
Sbjct: 948 VFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAV 1001
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 100 bits (249), Expect = 2e-20
Identities = 97/301 (32%), Positives = 123/301 (40%), Gaps = 71/301 (23%)
Query: 645 RSLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWV--------VDFTTPHGRFR 696
+S+ W G ISNF YLM LN LAGR D +PV PW+ VD T P FR
Sbjct: 2692 KSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPK-TFR 2750
Query: 697 DLRKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPP--HVPHHISDVLSDITYYVYKA 754
+L K Q D ++ + GE P H H S + +Y V
Sbjct: 2751 NLAKPM------GAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLV--- 2801
Query: 755 RRTPRSVLC-----GH----------VRAQWEPHEYPASMERMQNWTPDECIPEFYTDPS 799
R P + + GH VR W Y AS M + E IPEF+ P
Sbjct: 2802 RMEPFTQIFLRLQGGHFDLADRMFHSVREAW----YSASKHNMAD--VKELIPEFFYLPE 2855
Query: 800 -IFRSIHPDMP---------DLDVPAWCSSS-QEFVAAHRALLESREVSRDLHHWIDLTF 848
+F S + D+ D+ +P W +EF+ HR LE VS LH WIDL F
Sbjct: 2856 FLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIF 2915
Query: 849 GYKLQGKEAVKEKNVCLHLV-----------DAHTHLASYGVV--------QLFDQPHPQ 889
GYK QG AV+ NV HL D A+ G + QLF +PHP
Sbjct: 2916 GYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPP 2975
Query: 890 R 890
+
Sbjct: 2976 K 2976
Score = 36.2 bits (82), Expect = 0.37
Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 13/102 (12%)
Query: 1922 YEIGVSQQDAHFHFHQIRL-QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG 1980
+E+G S++ A + L Q+ GH+ V C + +SGS+DRT +W L
Sbjct: 3105 WEMGTSKEKAK----TVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLS 3160
Query: 1981 DGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGA-VHVW 2021
T HR V + E +VSC G +HVW
Sbjct: 3161 FLTQ-------LRGHRAPVSALCINELTGDIVSCAGTYIHVW 3195
>gi|154240744 neurobeachin-like 1 isoform 2 [Homo sapiens]
Length = 1335
Score = 95.9 bits (237), Expect = 4e-19
Identities = 76/241 (31%), Positives = 109/241 (45%), Gaps = 29/241 (12%)
Query: 647 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 699
L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL
Sbjct: 713 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 772
Query: 700 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 758
K +N K K + YE G + H H S+ + Y + T
Sbjct: 773 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 827
Query: 759 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 807
+ R A + H PA+ + + + D E IPEF+ P + +
Sbjct: 828 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 887
Query: 808 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 862
+ D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N
Sbjct: 888 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 947
Query: 863 V 863
V
Sbjct: 948 V 948
>gi|191252801 WDFY family member 4 [Homo sapiens]
Length = 3184
Score = 89.7 bits (221), Expect = 3e-17
Identities = 91/305 (29%), Positives = 120/305 (39%), Gaps = 64/305 (20%)
Query: 645 RSLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPHGR------FRD 697
R ++ W ISNF YLM LN AGR D +PV PWV+ D+T+ FRD
Sbjct: 2536 RIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLADYTSETLNLANPKIFRD 2595
Query: 698 LRKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRT 757
L K K +++L F Q F G+ H+ + S I Y R
Sbjct: 2596 LSKPMGAQTK-ERKLKFI-----QRFKEVEKTEGDMTVQCHYYTHYSSAIIVASYLVRMP 2649
Query: 758 P-RSVLCG--------------HVRAQWEPHEYPASMERMQNWTPDECIPEFYTDPSIFR 802
P C V++ WE AS E M + E PEF+ P
Sbjct: 2650 PFTQAFCALQGGSFDVADRMFHSVKSTWES----ASRENMSDVR--ELTPEFFYLPEFLT 2703
Query: 803 SIH----------PDMPDLDVPAWCSSS-QEFVAAHRALLESREVSRDLHHWIDLTFGYK 851
+ + + D+ +P W ++F++ HR LES VS +LHHWIDL FGYK
Sbjct: 2704 NCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDLIFGYK 2763
Query: 852 LQGKEAVKEKNV-----------CLHLVDAHTHLASYGVV--------QLFDQPHPQRLA 892
QG AV N+ + D G V QLF +PHP R A
Sbjct: 2764 QQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPHPARTA 2823
Query: 893 GAPAL 897
L
Sbjct: 2824 AGKPL 2828
Score = 35.4 bits (80), Expect = 0.63
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 1941 QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVF 2000
Q+ GH+ AV C+A + +SGS+D T LW L + T A HR+ +
Sbjct: 2976 QALYGHTQAVTCLAASVTFSLLVSGSQDCTCILWDLDHLTHVTRLPA-------HREGIS 3028
Query: 2001 FVGQLEAPQHVVSCDGA-VHVWD 2022
+ + +VSC GA + +W+
Sbjct: 3029 AITISDVSGTIVSCAGAHLSLWN 3051
>gi|54292123 lysosomal trafficking regulator [Homo sapiens]
Length = 3801
Score = 68.9 bits (167), Expect = 5e-11
Identities = 83/311 (26%), Positives = 122/311 (39%), Gaps = 54/311 (17%)
Query: 651 WVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPHGRFRDL----RKSK--- 702
W G+I+NF YL LN+ AGR D +PV P+++ D+ + DL SK
Sbjct: 3135 WYTGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILADYVSETLDLNDLLIYRNLSKPIA 3194
Query: 703 -FRLNKGDKQLDFTYEMTRQAFVAGGAGGGE-PPHVPHHISDVLSDI-TYYVYKARRTPR 759
K D+ +D TY+ + + G PP P+H S+ T + R P
Sbjct: 3195 VQYKEKEDRYVD-TYKYLEEEYRKGAREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPF 3253
Query: 760 SVLCGHVRAQWEPHEYPASMERMQNWT-----------PDECIPEFYTDPSIF------- 801
+ + + Q + + P N T E IPEF+ P
Sbjct: 3254 TKM--FLAYQDQSFDIPDRTFHSTNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFD 3311
Query: 802 ---RSIHPDMPDLDVPAWCSSSQE-FVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEA 857
R + +++P W + F+ HR LES VS+++ WIDL FGYK +GK +
Sbjct: 3312 FGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESDYVSQNICQWIDLVFGYKQKGKAS 3371
Query: 858 VKEKNVC----------------LHLVDAHTHLASYGVV--QLFDQPHPQRLAGAPALAP 899
V+ NV + T + +YG QLF H R +
Sbjct: 3372 VQAINVFHPATYFGMDVSAVEDPVQRRALETMIKTYGQTPRQLFHMAHVSRPGAKLNIEG 3431
Query: 900 EPPLIPKLLVQ 910
E P LLVQ
Sbjct: 3432 ELPAAVGLLVQ 3442
>gi|89886480 zinedin isoform 2 [Homo sapiens]
Length = 760
Score = 62.4 bits (150), Expect = 5e-09
Identities = 65/260 (25%), Positives = 102/260 (39%), Gaps = 21/260 (8%)
Query: 1940 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG----DGTSETAPRLVYTQH 1995
+ +F H G V VA S+ ++ SG D + W + + DG + V H
Sbjct: 491 IHAFRAHRGPVLAVAMGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGH 550
Query: 1996 RKSVFFVGQLEAPQHVVSC--DGAVHVWDPFTGK-----TLRTVEPLDSRVPLTAVAVMP 2048
+V+ + Q + SC DG V +WDP + T T + + P
Sbjct: 551 GDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAFTSTEP 610
Query: 2049 APHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGF 2108
A H + S D+ L ++ L E R G P + + P+ +
Sbjct: 611 A-HIVASFRSGDTVLYDMEVGSALLTLESR--GSSGPTQINQVVSHPNQPLTITAHDDRG 667
Query: 2109 MVLLDTRTGLVLRGWPAHEGDILQIKAVE--GSVLVSSSSDHSLTVW----KELEQKPTH 2162
+ LD RTG + AH D + AV+ G+ L+S S D SL +W K Q+ T
Sbjct: 668 IRFLDNRTGKPVHSMVAHL-DAVTCLAVDPNGAFLMSGSHDCSLRLWSLDNKTCVQEITA 726
Query: 2163 HYKSASDPIHTFDLYGSEVV 2182
H K + IH + S+ +
Sbjct: 727 HRKKHEEAIHAVACHPSKAL 746
>gi|89886477 zinedin isoform 1 [Homo sapiens]
Length = 753
Score = 62.4 bits (150), Expect = 5e-09
Identities = 65/260 (25%), Positives = 102/260 (39%), Gaps = 21/260 (8%)
Query: 1940 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG----DGTSETAPRLVYTQH 1995
+ +F H G V VA S+ ++ SG D + W + + DG + V H
Sbjct: 484 IHAFRAHRGPVLAVAMGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGH 543
Query: 1996 RKSVFFVGQLEAPQHVVSC--DGAVHVWDPFTGK-----TLRTVEPLDSRVPLTAVAVMP 2048
+V+ + Q + SC DG V +WDP + T T + + P
Sbjct: 544 GDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAFTSTEP 603
Query: 2049 APHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGF 2108
A H + S D+ L ++ L E R G P + + P+ +
Sbjct: 604 A-HIVASFRSGDTVLYDMEVGSALLTLESR--GSSGPTQINQVVSHPNQPLTITAHDDRG 660
Query: 2109 MVLLDTRTGLVLRGWPAHEGDILQIKAVE--GSVLVSSSSDHSLTVW----KELEQKPTH 2162
+ LD RTG + AH D + AV+ G+ L+S S D SL +W K Q+ T
Sbjct: 661 IRFLDNRTGKPVHSMVAHL-DAVTCLAVDPNGAFLMSGSHDCSLRLWSLDNKTCVQEITA 719
Query: 2163 HYKSASDPIHTFDLYGSEVV 2182
H K + IH + S+ +
Sbjct: 720 HRKKHEEAIHAVACHPSKAL 739
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 60.8 bits (146), Expect = 1e-08
Identities = 71/309 (22%), Positives = 122/309 (39%), Gaps = 42/309 (13%)
Query: 1939 RLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKS 1998
+ F H+ V+ V + F + S+D+++++W +Y R +Y+ +R +
Sbjct: 94 KFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQ---------RFLYSLYRHT 144
Query: 1999 VFFVGQLEAPQH--VVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 2054
+ +P +VSC D + +WD T K + V V T I
Sbjct: 145 HWVRCAKFSPDGRLIVSCSEDKTIKIWDT-TNK--QCVNNFSDSVGFANFVDFNPSGTCI 201
Query: 2055 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 2114
A SD T++ D R L +++ + G V ++ PSG ++ S G + +LD
Sbjct: 202 ASAGSDQTVKVWDVRVNKLLQHYQV----HSGGVNCISFHPSGNYLITASSDGTLKILDL 257
Query: 2115 RTGLVLRGWPAHEGDILQIKAVEGSVL-VSSSSDHSLTVWK----ELEQK-------PTH 2162
G ++ H G + + +G L S +D + +W+ EL K
Sbjct: 258 LEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDELHCKGLTKRNLKRL 317
Query: 2163 HYKSASDPIHTFDLY-------GSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTL 2215
H+ S P H D+Y +V T ++ K+ V L LS ++ T
Sbjct: 318 HFDS---PPHLLDIYPRTPHPHEEKVETVEINPKLEVIDLQISTPPVMDILSFDSTTTTE 374
Query: 2216 TSLALLPTK 2224
TS LP K
Sbjct: 375 TSGRTLPDK 383
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 58.9 bits (141), Expect = 5e-08
Identities = 61/224 (27%), Positives = 88/224 (39%), Gaps = 17/224 (7%)
Query: 1937 QIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHR 1996
Q R F GH AV CV S SGS+D+TVR+W G+ T V+ H
Sbjct: 13 QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST-------VFRAHT 65
Query: 1997 KSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 2054
+V V Q V S D V VW K L + L + A I
Sbjct: 66 ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFS---LSQHINWVRCAKFSPDGRLI 122
Query: 2055 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 2114
AS D T++ D H + G G V + PSG + A + + D
Sbjct: 123 VSASDDKTVKLWDKSSRECVHSYCEHG----GFVTYVDFHPSGTCIAAAGMDNTVKVWDV 178
Query: 2115 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELE 2157
RT +L+ + H + + G+ L+++SSD +L + +E
Sbjct: 179 RTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLME 222
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 58.9 bits (141), Expect = 5e-08
Identities = 61/224 (27%), Positives = 88/224 (39%), Gaps = 17/224 (7%)
Query: 1937 QIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHR 1996
Q R F GH AV CV S SGS+D+TVR+W G+ T V+ H
Sbjct: 51 QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST-------VFRAHT 103
Query: 1997 KSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 2054
+V V Q V S D V VW K L + L + A I
Sbjct: 104 ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFS---LSQHINWVRCAKFSPDGRLI 160
Query: 2055 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 2114
AS D T++ D H + G G V + PSG + A + + D
Sbjct: 161 VSASDDKTVKLWDKSSRECVHSYCEHG----GFVTYVDFHPSGTCIAAAGMDNTVKVWDV 216
Query: 2115 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELE 2157
RT +L+ + H + + G+ L+++SSD +L + +E
Sbjct: 217 RTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLME 260
Score = 43.1 bits (100), Expect = 0.003
Identities = 57/266 (21%), Positives = 104/266 (39%), Gaps = 31/266 (11%)
Query: 1943 FPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVFFV 2002
F GH AV CV + SGS D + +W + + +T H+ +V V
Sbjct: 15 FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHM-------KPQSRAYRFTGHKDAVTCV 67
Query: 2003 GQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPH-----TSI 2054
H++ S D V +W P +S V A + + H S
Sbjct: 68 -NFSPSGHLLASGSRDKTVRIWVPNVKG--------ESTVFRAHTATVRSVHFCSDGQSF 118
Query: 2055 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 2114
AS D T++ + + F L +N VR SP GR +V+ + L D
Sbjct: 119 VTASDDKTVKVWATHRQ--KFLFSLSQHIN--WVRCAKFSPDGRLIVSASDDKTVKLWDK 174
Query: 2115 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELEQKPTHHYKSASDPIH- 2172
+ + + H G + + G+ + ++ D+++ VW + HY+ S ++
Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 234
Query: 2173 -TFDLYGSEVVTGTVSNKIGVCSLLE 2197
+F G+ ++T + + + + L+E
Sbjct: 235 LSFHPSGNYLITASSDSTLKILDLME 260
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 58.9 bits (141), Expect = 5e-08
Identities = 61/224 (27%), Positives = 88/224 (39%), Gaps = 17/224 (7%)
Query: 1937 QIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHR 1996
Q R F GH AV CV S SGS+D+TVR+W G+ T V+ H
Sbjct: 51 QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST-------VFRAHT 103
Query: 1997 KSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 2054
+V V Q V S D V VW K L + L + A I
Sbjct: 104 ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFS---LSQHINWVRCAKFSPDGRLI 160
Query: 2055 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 2114
AS D T++ D H + G G V + PSG + A + + D
Sbjct: 161 VSASDDKTVKLWDKSSRECVHSYCEHG----GFVTYVDFHPSGTCIAAAGMDNTVKVWDV 216
Query: 2115 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELE 2157
RT +L+ + H + + G+ L+++SSD +L + +E
Sbjct: 217 RTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLME 260
Score = 43.1 bits (100), Expect = 0.003
Identities = 57/266 (21%), Positives = 104/266 (39%), Gaps = 31/266 (11%)
Query: 1943 FPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVFFV 2002
F GH AV CV + SGS D + +W + + +T H+ +V V
Sbjct: 15 FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHM-------KPQSRAYRFTGHKDAVTCV 67
Query: 2003 GQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPH-----TSI 2054
H++ S D V +W P +S V A + + H S
Sbjct: 68 -NFSPSGHLLASGSRDKTVRIWVPNVKG--------ESTVFRAHTATVRSVHFCSDGQSF 118
Query: 2055 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 2114
AS D T++ + + F L +N VR SP GR +V+ + L D
Sbjct: 119 VTASDDKTVKVWATHRQ--KFLFSLSQHIN--WVRCAKFSPDGRLIVSASDDKTVKLWDK 174
Query: 2115 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELEQKPTHHYKSASDPIH- 2172
+ + + H G + + G+ + ++ D+++ VW + HY+ S ++
Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 234
Query: 2173 -TFDLYGSEVVTGTVSNKIGVCSLLE 2197
+F G+ ++T + + + + L+E
Sbjct: 235 LSFHPSGNYLITASSDSTLKILDLME 260
>gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens]
Length = 919
Score = 55.8 bits (133), Expect = 5e-07
Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 14/223 (6%)
Query: 1938 IRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1997
+R + H G++ CVA +GS D+ V++ P + + T P L ++ H
Sbjct: 652 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPF--NAETCNATGPDLEFSMHDG 709
Query: 1998 SVFFVGQLEAPQH----VVSC---DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAP 2050
++ + +E P+ ++S D ++ D G+ L + + +A+
Sbjct: 710 TIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI----LALYTWS 765
Query: 2051 HTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMV 2110
I S D T+RF D R P V ++A+ PSGR + G +
Sbjct: 766 GWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCM 825
Query: 2111 LLDTRTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTV 2152
L D R G +++ + H D+ ++ G+ L++ S D + V
Sbjct: 826 LYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 868
>gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens]
Length = 927
Score = 55.8 bits (133), Expect = 5e-07
Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 14/223 (6%)
Query: 1938 IRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1997
+R + H G++ CVA +GS D+ V++ P + + T P L ++ H
Sbjct: 660 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPF--NAETCNATGPDLEFSMHDG 717
Query: 1998 SVFFVGQLEAPQH----VVSC---DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAP 2050
++ + +E P+ ++S D ++ D G+ L + + +A+
Sbjct: 718 TIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI----LALYTWS 773
Query: 2051 HTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMV 2110
I S D T+RF D R P V ++A+ PSGR + G +
Sbjct: 774 GWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCM 833
Query: 2111 LLDTRTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTV 2152
L D R G +++ + H D+ ++ G+ L++ S D + V
Sbjct: 834 LYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 876
>gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens]
Length = 920
Score = 55.8 bits (133), Expect = 5e-07
Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 14/223 (6%)
Query: 1938 IRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1997
+R + H G++ CVA +GS D+ V++ P + + T P L ++ H
Sbjct: 653 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPF--NAETCNATGPDLEFSMHDG 710
Query: 1998 SVFFVGQLEAPQH----VVSC---DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAP 2050
++ + +E P+ ++S D ++ D G+ L + + +A+
Sbjct: 711 TIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI----LALYTWS 766
Query: 2051 HTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMV 2110
I S D T+RF D R P V ++A+ PSGR + G +
Sbjct: 767 GWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCM 826
Query: 2111 LLDTRTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTV 2152
L D R G +++ + H D+ ++ G+ L++ S D + V
Sbjct: 827 LYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 869
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 55.1 bits (131), Expect = 8e-07
Identities = 60/177 (33%), Positives = 70/177 (39%), Gaps = 18/177 (10%)
Query: 141 VAPPTRGPTGPRPGPASPGALALIALRVSDPLRKALRQTRVLKSRRKPRRLRLQCMLVRV 200
V PP RG T P P A GA A A P + + R R
Sbjct: 99 VQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATA 158
Query: 201 VLSLTPSFPEPSALSDPSRWSPVLAPGSLCPAAPGAQDPRRG-KRAPRPPLRRRR--LPA 257
S P+ P P A R +P+ AP PAAP A P G +RAP P + R LP
Sbjct: 159 PPSPGPAQPGPRA----QRAAPLAAPPP-APAAPPAVAPPAGPRRAPPPAVAAREPPLPP 213
Query: 258 AASAPAP----VPRPSQPRRPGTPEAVASRAVAGLSPALPPGGLEEMAQGSGGREGA 310
PAP P P QP+ P PE A RA A P L E+ + GG GA
Sbjct: 214 PPQPPAPPQQQQPPPPQPQPP--PEGGAVRA----GGAARPVSLREVVRYLGGSGGA 264
Score = 47.0 bits (110), Expect = 2e-04
Identities = 37/106 (34%), Positives = 44/106 (41%), Gaps = 16/106 (15%)
Query: 233 APGAQDPRRGKRAPRPPLRRRRLPAAASAPAPVPRPSQPRRPG---------TPEAVASR 283
A Q PRRG P PP R PAAA+A AP P P+ P P P A A+
Sbjct: 96 AARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAA 155
Query: 284 AVAGLSPA-LPPGGLEEMA------QGSGGREGALRTPAGGWHSPP 322
A A SP PG + A + A+ PAG +PP
Sbjct: 156 ATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPP 201
Score = 36.2 bits (82), Expect = 0.37
Identities = 43/174 (24%), Positives = 62/174 (35%), Gaps = 9/174 (5%)
Query: 183 KSRRKPRRLRLQCMLVRVVLSLTPSFPEPSALSDPSRWSPVLAPGSLCPAAPGAQDPRRG 242
++R + +L Q ++RV + S+ + + P R + AP AP A
Sbjct: 68 RTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAP 127
Query: 243 KRAPRPPLRRRRLPAAASAPAP------VPRPSQPRRPGTPEAVASRAVAGLSPALPPGG 296
P PP + AAA A AP P P P P A RA +P P
Sbjct: 128 PPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP-GPAQPGPRAQRAAPLAAPPPAPAA 186
Query: 297 LEEMAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGG 350
+A +G R PA PP P + ++ P+ P GG
Sbjct: 187 PPAVAPPAGPRRAP--PPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGG 238
Score = 33.1 bits (74), Expect = 3.1
Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 14/110 (12%)
Query: 1398 EAEAVSLGRLSDKSSTSETSLGEERAP--DEGGAPVDKSSLRSGDSSQDLKQSEGSEEEE 1455
E EA + GRL T LG P D G +S R S + ++ +EEE
Sbjct: 278 EEEAAARGRLE------RTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEE 331
Query: 1456 EEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGGDGEEEE 1505
E++D E+E E+++V+ SE+ SD + G G +E
Sbjct: 332 EDDD------EDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKE 375
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 51.6 bits (122), Expect = 9e-06
Identities = 94/364 (25%), Positives = 132/364 (36%), Gaps = 72/364 (19%)
Query: 21 QEKPGPAAWPREGAGGVAGSGDRQSTSSPPARGVQTLPRLDGRPL--------------- 65
QE P P A P G AG+ R+ + LPR R L
Sbjct: 1984 QEAPSPEALPSPGQEPAAGASPRRGELRRGSSAESALPRAGPRELGRGLHKAASVELPQR 2043
Query: 66 -YPQTGGRRLTPTWCWVWGLLHEGEQITASAPHGRRRCLFSAPSTHR---LQAP----IS 117
P G RL G L EGE R+R L P + L+ P +
Sbjct: 2044 RSPSPGATRLAR------GGLGEGE-YAQRLQALRQRLLRGGPEDGKVSGLRGPLLESLG 2096
Query: 118 WRRRD---ARAANARPGANHRPLLGNVAPPTRGPTGPRPGPASPGALALIALRVSDPLRK 174
R RD ARAA++ +H+P L N RG L+ S +
Sbjct: 2097 GRARDPRMARAASSEAAPHHQPPLEN-----RG------------------LQKSSSFSQ 2133
Query: 175 ALRQTRVLKSRRKPRRLRLQCMLVRVVLSLTPSFPEPSALSDPSRWSPVLAPGSLCPAAP 234
+ R R + L+ + R+ P SALS+ SP P + P+ P
Sbjct: 2134 GEAEPR---GRHRRAGAPLEIPVARLGARRLQESPSLSALSEAQPSSPA-RPSAPKPSTP 2189
Query: 235 GAQDP--RRGKRAPRPPLRRRRLPAAASAPAPVPRPSQPRRPG-TPEAVASRAVAGLSPA 291
+ +P AP+PP + PA AP P P P + +P P+A+ + A+ P
Sbjct: 2190 KSAEPSATTPSDAPQPPAPQ---PAQDKAPEPRPEPVRASKPAPPPQALQTLAL----PL 2242
Query: 292 LPPGGLEEMAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGT 351
P + + Q SG +G + PA S P P R V P + P+ GG
Sbjct: 2243 TPYAQIIQSLQLSGHAQGPSQGPAAP-PSEPKPHAAVFAR-VASPPPGAPEKRVPSAGGP 2300
Query: 352 HVVA 355
V+A
Sbjct: 2301 PVLA 2304
Score = 43.5 bits (101), Expect = 0.002
Identities = 69/234 (29%), Positives = 92/234 (39%), Gaps = 41/234 (17%)
Query: 105 SAPSTHRLQAPISWRRRDARAANARPGANHRPLLGNVAPPTRGPTGPRPGPAS---PGAL 161
+ PS +AP++ +R A ARP + L +AP P P+S P +
Sbjct: 2776 AVPSAAHQEAPVT-----SRPARARPPDSPTSLAPPLAPAAPTPPSVTVSPSSPPTPPSQ 2830
Query: 162 ALIALR-VSDPLRKALRQTRVLKSRRKPRRLRLQCMLVRVVLSLTPSFPEPSAL------ 214
AL +L+ V P + R+ R L++ R P L V TPS P+P L
Sbjct: 2831 ALSSLKAVGPPPQTPPRRHRGLQAAR-PAEPTLPSTHV------TPSEPKPFVLDTGTPI 2883
Query: 215 --SDP------SRWSPVLAPGSLCPAAPGAQDPRRGKRAPRPPLRRRRLPAAASAPAP-- 264
S P S +PV S A P + P AP PP ++ + +PA
Sbjct: 2884 PASTPQGVKPVSSSTPVYVVTSFVSAPPAPEPP-----APEPPPEPTKVTVQSLSPAKEV 2938
Query: 265 VPRP-SQPRRPGTPEAVASRAVAGLSPALPPGGLEEMAQGSGGREGALRTPAGG 317
V P S PR PE R P P LEE A+G G A R A G
Sbjct: 2939 VSSPGSSPRSSPRPEGTTLRQG---PPQKPYTFLEEKARGRFGVVRACRENATG 2989
Score = 35.8 bits (81), Expect = 0.49
Identities = 83/359 (23%), Positives = 121/359 (33%), Gaps = 68/359 (18%)
Query: 6 SKFQAPPPQFQRMNQQEKPGPAAWPREGAGGVAGSGDRQSTSSPPARGVQTLPRLDGRPL 65
SK PP R+ ++ PGP A P +T + P R Q P L
Sbjct: 304 SKSALLPPPSPRVGKRSPPGPPAQP-------------AATPTSPHRRTQE-PVLPEDTT 349
Query: 66 YPQTGGRRLTPTWCWVWGLLHEGEQITASAPHGRRRCLFSAPSTHRLQAPI--------- 116
+ G++ + + G Q S GR L +P R + I
Sbjct: 350 TEEKRGKKSKSSGPSLAGTAESRPQTPLSEASGRLSALGRSPRLVRAGSRILDKLQFFEE 409
Query: 117 ---SWRRRDARAANARPGANHRPLLGNVAPPT-RGPTGPRPGPA-----SPGALA----L 163
S R D+ A RP R P + RG PG + +PG++A L
Sbjct: 410 RRRSLERSDSPPAPLRPWVPLRKARSLEQPKSERGAPWGTPGASQEELRAPGSVAERRRL 469
Query: 164 IALRVSD--------------PLRKALRQTRVLKSRRKPRRLRLQCMLVRVVLSLTPSFP 209
+ + LR A R+ +S + +R L R L PS
Sbjct: 470 FQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHESL-RATLQRAPSPR 528
Query: 210 EPS---ALSDPS--RWSPVLAPGSLCPAAPGAQDPRRGKRAPRPPLRRRRLPAAASAPAP 264
EP S PS + S ++P + P +P + + K P R R PA + P
Sbjct: 529 EPGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSAE----KPGDEPGRPRSRGPAGRTEPGE 584
Query: 265 VPRPSQPRRPGTPEAVASRAVAGLSPALPPGGLEEMAQGSGGREGALRTPAGGWHSPPS 323
P+ RR P SRA+ +PP + E + P G PP+
Sbjct: 585 GPQQEVRRRDQFP-LTRSRAIQECRSPVPPPAADP-------PEARTKAPPGRKREPPA 635
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 51.2 bits (121), Expect = 1e-05
Identities = 56/236 (23%), Positives = 95/236 (40%), Gaps = 28/236 (11%)
Query: 1945 GHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGD-----GTSETAPRLVYTQHRKSV 1999
GH+ AV CV S++D +GSKDRT ++W L + G + Y + V
Sbjct: 1332 GHTKAVLCVD--STDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLV 1389
Query: 2000 FFVGQLEAPQ----------HVVSCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPA 2049
F V ++ G V + D + T RTV + +A+ P
Sbjct: 1390 FTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQINQIALNPT 1449
Query: 2050 PHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS-VVAGFSSGF 2108
+ A+S + +R D ++ Q +L G L P + + SG+ ++ G +
Sbjct: 1450 --GTFLYAASGNAVRMWDLKR--FQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDHY 1505
Query: 2109 MVLLDTRTGLVLRGWPAH-----EGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 2159
+ + D G + P H D ++ ++G L S S D+ + W +L QK
Sbjct: 1506 IKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKW-DLTQK 1560
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 49.3 bits (116), Expect = 4e-05
Identities = 52/220 (23%), Positives = 91/220 (41%), Gaps = 20/220 (9%)
Query: 1939 RLQSFPGHSGAVKC-VAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1997
+LQ H+ V V +S +G D V LW + S T +T +
Sbjct: 12 KLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTG----HTSPVE 67
Query: 1998 SVFFVGQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 2054
SV +L P+ ++ S G++ VWD K LRT+ + + + ++ P +
Sbjct: 68 SV----RLNTPEELIVAGSQSGSIRVWDLEAAKILRTL--MGHKANICSLDFHPYGEF-V 120
Query: 2055 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 2114
S D+ ++ D R+ G +R + VR L SP G+ + + + L D
Sbjct: 121 ASGSQDTNIKLWDIRRKGCVFRYRG----HSQAVRCLRFSPDGKWLASAADDHTVKLWDL 176
Query: 2115 RTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTVW 2153
G ++ +P H G + ++ +L S SSD ++ W
Sbjct: 177 TAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFW 216
Score = 38.5 bits (88), Expect = 0.075
Identities = 17/40 (42%), Positives = 22/40 (55%)
Query: 1940 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1979
+ FPGH+G V V +E SGS DRT+R W L +
Sbjct: 182 MSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKF 221
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 48.5 bits (114), Expect = 7e-05
Identities = 57/239 (23%), Positives = 98/239 (41%), Gaps = 35/239 (14%)
Query: 1941 QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVF 2000
++ GH + VA S + +S S D+T+++W + + L + +
Sbjct: 81 KTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV--------SSGKCLKTLKGHSNYV 132
Query: 2001 FVGQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 2057
F +++ S D +V +WD TGK L+T+ P S P++AV + I +
Sbjct: 133 FCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL-PAHSD-PVSAVH-FNRDGSLIVSS 189
Query: 2058 SSDSTLRFVD-----CRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLL 2112
S D R D C K + + NP V + SP+G+ ++A + L
Sbjct: 190 SYDGLCRIWDTASGQCLKTLIDDD-------NPP-VSFVKFSPNGKYILAATLDNTLKLW 241
Query: 2113 DTRTGLVLRGWPAHEGD----ILQIKAVEGSVLVSSSSDHSLTVW----KELEQKPTHH 2163
D G L+ + H+ + G +VS S D+ + +W KE+ QK H
Sbjct: 242 DYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH 300
Score = 40.0 bits (92), Expect = 0.026
Identities = 50/220 (22%), Positives = 91/220 (41%), Gaps = 15/220 (6%)
Query: 1940 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSV 1999
L++ GHS V C + +SGS D +VR+W + +T P H V
Sbjct: 122 LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT--GKCLKTLP-----AHSDPV 174
Query: 2000 FFVGQLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 2057
V +VS DG +WD +G+ L+T+ D P++ V P I A
Sbjct: 175 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID-DDNPPVSFVKFSP-NGKYILAA 232
Query: 2058 SSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTG 2117
+ D+TL+ D K G + G + A G+ +V+G + + + +T
Sbjct: 233 TLDNTLKLWDYSK-GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTK 291
Query: 2118 LVLRGWPAHEGDILQIKAVEGSVLVSSS---SDHSLTVWK 2154
+++ H ++ +++S+ +D ++ +WK
Sbjct: 292 EIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 48.5 bits (114), Expect = 7e-05
Identities = 57/239 (23%), Positives = 98/239 (41%), Gaps = 35/239 (14%)
Query: 1941 QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVF 2000
++ GH + VA S + +S S D+T+++W + + L + +
Sbjct: 81 KTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV--------SSGKCLKTLKGHSNYV 132
Query: 2001 FVGQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 2057
F +++ S D +V +WD TGK L+T+ P S P++AV + I +
Sbjct: 133 FCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL-PAHSD-PVSAVH-FNRDGSLIVSS 189
Query: 2058 SSDSTLRFVD-----CRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLL 2112
S D R D C K + + NP V + SP+G+ ++A + L
Sbjct: 190 SYDGLCRIWDTASGQCLKTLIDDD-------NPP-VSFVKFSPNGKYILAATLDNTLKLW 241
Query: 2113 DTRTGLVLRGWPAHEGD----ILQIKAVEGSVLVSSSSDHSLTVW----KELEQKPTHH 2163
D G L+ + H+ + G +VS S D+ + +W KE+ QK H
Sbjct: 242 DYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH 300
Score = 40.0 bits (92), Expect = 0.026
Identities = 50/220 (22%), Positives = 91/220 (41%), Gaps = 15/220 (6%)
Query: 1940 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSV 1999
L++ GHS V C + +SGS D +VR+W + +T P H V
Sbjct: 122 LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT--GKCLKTLP-----AHSDPV 174
Query: 2000 FFVGQLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 2057
V +VS DG +WD +G+ L+T+ D P++ V P I A
Sbjct: 175 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID-DDNPPVSFVKFSP-NGKYILAA 232
Query: 2058 SSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTG 2117
+ D+TL+ D K G + G + A G+ +V+G + + + +T
Sbjct: 233 TLDNTLKLWDYSK-GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTK 291
Query: 2118 LVLRGWPAHEGDILQIKAVEGSVLVSSS---SDHSLTVWK 2154
+++ H ++ +++S+ +D ++ +WK
Sbjct: 292 EIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331
>gi|239745807 PREDICTED: keratin associated protein 4-9 [Homo
sapiens]
Length = 254
Score = 48.5 bits (114), Expect = 7e-05
Identities = 69/268 (25%), Positives = 80/268 (29%), Gaps = 76/268 (28%)
Query: 111 RLQAPISWRRRDARAANARPGANHRPLLGNVAPPTRGPTGPRPGPASPGALALIALRVSD 170
R A S RR A A RP A PP P P A P A +L A
Sbjct: 7 RAAAKTSVRRPAAAPAAVRPPA--------AGPPAAAPAVVYPAAAGPSAASLCAAN--- 55
Query: 171 PLRKALRQTRVLKSRRKPRRLRLQCMLVRVVLSLTPSFPEPSALSDPSRWSPVLAPGSLC 230
P P P+A+ P P AP +C
Sbjct: 56 -----------------------------------PLVPAPAAVRPPVAGPPATAPAVVC 80
Query: 231 PAAPGAQDPRRGKRAPRPPLRRRRLPAAASAPAPVPRPSQPRRPGTPEAVASRAVAGLSP 290
PAA G RA P A APA V RP+ +P AVA AV
Sbjct: 81 PAAAGPS--AASLRAANP---------LAVAPAAVRRPAATLGAASPAAVAPAAVC--PA 127
Query: 291 ALPPGGLEEMAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGG 350
A P A A +PA L+++P APA
Sbjct: 128 AASPSAASLCAASPTAAAPAAASPAAA-----------------APLAVNPAAAAPAAAC 170
Query: 351 THVVALVPARWLASLRDRRLPLGPCPRA 378
VA PA LA + P P P A
Sbjct: 171 VQSVAESPATPLAIAQPVSSPAAPAPCA 198
Score = 44.3 bits (103), Expect = 0.001
Identities = 50/171 (29%), Positives = 69/171 (40%), Gaps = 26/171 (15%)
Query: 136 PLLGNVAPPTRGPTGPRPGPASPGAL--ALIALRVSDPLRKALRQTRVLKSRRKPRRLRL 193
P V PP GP P P A + +LR ++PL A R +P
Sbjct: 59 PAPAAVRPPVAGPPATAPAVVCPAAAGPSAASLRAANPLAVAPAAVR------RP----- 107
Query: 194 QCMLVRVVLSLTPSFPEPSALSDPSRWSPVLAPGSLCPAAPGAQDPRRGKRAPRPPLRRR 253
+ + +P+ P+A+ P+ SP A SLC A+P A P A PL
Sbjct: 108 ----AATLGAASPAAVAPAAVC-PAAASPSAA--SLCAASPTAAAPAAASPAAAAPL--- 157
Query: 254 RLPAAASAPAPVPRPSQPRRPGTPEAVASRAVAGLSP---ALPPGGLEEMA 301
+ AA+APA S P TP A+A + +P A+PP E A
Sbjct: 158 AVNPAAAAPAAACVQSVAESPATPLAIAQPVSSPAAPAPCAVPPLAAEPTA 208
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 103,083,733
Number of Sequences: 37866
Number of extensions: 5852628
Number of successful extensions: 42397
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 208
Number of HSP's successfully gapped in prelim test: 1137
Number of HSP's that attempted gapping in prelim test: 30793
Number of HSP's gapped (non-prelim): 9279
length of query: 2240
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2122
effective length of database: 13,779,330
effective search space: 29239738260
effective search space used: 29239738260
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.