Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 239749951

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
         (2639 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]            5662   0.0  
gi|116284392 mucin 2 precursor [Homo sapiens]                        2806   0.0  
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]   1271   0.0  
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]     1152   0.0  
gi|161019170 mucin 5AC [Homo sapiens]                                1135   0.0  
gi|151301154 mucin 6, gastric [Homo sapiens]                          817   0.0  
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ...   666   0.0  
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ...   663   0.0  
gi|89191868 von Willebrand factor preproprotein [Homo sapiens]        569   e-161
gi|239755460 PREDICTED: similar to mucin, partial [Homo sapiens]      536   e-151
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]             430   e-119
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]             430   e-119
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]             430   e-119
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]             430   e-119
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]             430   e-119
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]             430   e-119
gi|134031945 SCO-spondin [Homo sapiens]                               410   e-114
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom...   337   9e-92
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom...   337   9e-92
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap...   337   9e-92
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]            291   6e-78
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                  232   3e-60
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                  232   3e-60
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                  232   3e-60
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                   232   3e-60
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]        228   5e-59
gi|91982772 mucin 17 [Homo sapiens]                                   228   8e-59
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ...   227   1e-58
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                       213   2e-54
gi|27881494 zonadhesin isoform 6 [Homo sapiens]                       213   2e-54

>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 5662 bits (14688), Expect = 0.0
 Identities = 2639/2639 (100%), Positives = 2639/2639 (100%)

Query: 1    MGLPLARLAAVCLALSLAGGSELQTEGRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCD 60
            MGLPLARLAAVCLALSLAGGSELQTEGRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCD
Sbjct: 1    MGLPLARLAAVCLALSLAGGSELQTEGRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCD 60

Query: 61   YNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTP 120
            YNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTP
Sbjct: 61   YNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTP 120

Query: 121  HYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSE 180
            HYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSE
Sbjct: 121  HYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSE 180

Query: 181  FLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDL 240
            FLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDL
Sbjct: 181  FLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDL 240

Query: 241  VPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTC 300
            VPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTC
Sbjct: 241  VPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTC 300

Query: 301  PGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVV 360
            PGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVV
Sbjct: 301  PGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVV 360

Query: 361  FKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQA 420
            FKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQA
Sbjct: 361  FKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQA 420

Query: 421  SQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIE 480
            SQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIE
Sbjct: 421  SQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIE 480

Query: 481  SANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARAC 540
            SANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARAC
Sbjct: 481  SANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARAC 540

Query: 541  TAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCG 600
            TAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCG
Sbjct: 541  TAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCG 600

Query: 601  CPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSC 660
            CPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSC
Sbjct: 601  CPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSC 660

Query: 661  TAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKE 720
            TAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKE
Sbjct: 661  TAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKE 720

Query: 721  CPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFD 780
            CPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFD
Sbjct: 721  CPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFD 780

Query: 781  GHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVI 840
            GHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVI
Sbjct: 781  GHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVI 840

Query: 841  QRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRS 900
            QRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRS
Sbjct: 841  QRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRS 900

Query: 901  NNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVF 960
            NNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVF
Sbjct: 901  NNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVF 960

Query: 961  SICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPI 1020
            SICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPI
Sbjct: 961  SICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPI 1020

Query: 1021 FCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLK 1080
            FCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLK
Sbjct: 1021 FCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLK 1080

Query: 1081 KCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCY 1140
            KCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCY
Sbjct: 1081 KCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCY 1140

Query: 1141 WEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTP 1200
            WEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTP
Sbjct: 1141 WEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTP 1200

Query: 1201 KLCCLWSDWINEDHPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVC 1260
            KLCCLWSDWINEDHPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVC
Sbjct: 1201 KLCCLWSDWINEDHPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVC 1260

Query: 1261 DVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTT 1320
            DVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTT
Sbjct: 1261 DVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTT 1320

Query: 1321 TVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1380
            TVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP
Sbjct: 1321 TVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1380

Query: 1381 TTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1440
            TTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT
Sbjct: 1381 TTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1440

Query: 1441 PTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAI 1500
            PTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAI
Sbjct: 1441 PTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAI 1500

Query: 1501 TTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTG 1560
            TTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTG
Sbjct: 1501 TTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTG 1560

Query: 1561 TQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTT 1620
            TQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTT
Sbjct: 1561 TQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTT 1620

Query: 1621 VTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESST 1680
            VTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESST
Sbjct: 1621 VTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESST 1680

Query: 1681 PQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG 1740
            PQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG
Sbjct: 1681 PQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG 1740

Query: 1741 TPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLND 1800
            TPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLND
Sbjct: 1741 TPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLND 1800

Query: 1801 TYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTP 1860
            TYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTP
Sbjct: 1801 TYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTP 1860

Query: 1861 SKPTPGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGL 1920
            SKPTPGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGL
Sbjct: 1861 SKPTPGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGL 1920

Query: 1921 QPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGV 1980
            QPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGV
Sbjct: 1921 QPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGV 1980

Query: 1981 YIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEV 2040
            YIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEV
Sbjct: 1981 YIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEV 2040

Query: 2041 YQSGINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEI 2100
            YQSGINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEI
Sbjct: 2041 YQSGINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEI 2100

Query: 2101 VSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSL 2160
            VSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSL
Sbjct: 2101 VSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSL 2160

Query: 2161 FAQCHALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLV 2220
            FAQCHALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLV
Sbjct: 2161 FAQCHALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLV 2220

Query: 2221 ECPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 2280
            ECPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP
Sbjct: 2221 ECPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 2280

Query: 2281 DNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCC 2340
            DNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCC
Sbjct: 2281 DNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCC 2340

Query: 2341 NITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVY 2400
            NITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVY
Sbjct: 2341 NITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVY 2400

Query: 2401 SSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRP 2460
            SSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRP
Sbjct: 2401 SSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRP 2460

Query: 2461 DNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIPGSITFMPNG 2520
            DNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIPGSITFMPNG
Sbjct: 2461 DNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIPGSITFMPNG 2520

Query: 2521 CCKTCTPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYSAKAQALDHSCS 2580
            CCKTCTPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYSAKAQALDHSCS
Sbjct: 2521 CCKTCTPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYSAKAQALDHSCS 2580

Query: 2581 CCKEEKTSQREVVLSCPNGGSLTHTYTHIESCQCQDTVCGLPTGTSRRARRSPRHLGSG 2639
            CCKEEKTSQREVVLSCPNGGSLTHTYTHIESCQCQDTVCGLPTGTSRRARRSPRHLGSG
Sbjct: 2581 CCKEEKTSQREVVLSCPNGGSLTHTYTHIESCQCQDTVCGLPTGTSRRARRSPRHLGSG 2639


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 2806 bits (7275), Expect = 0.0
 Identities = 1307/1350 (96%), Positives = 1316/1350 (97%), Gaps = 8/1350 (0%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 3830 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3889

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3890 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3949

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3950 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4009

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 4010 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4069

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 4070 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4129

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 4130 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4189

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   TGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS
Sbjct: 4190 PTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 4249

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTP 1769
            TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTP
Sbjct: 4250 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTP 4309

Query: 1770 TPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTL 1829
            TPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTL
Sbjct: 4310 TPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTL 4369

Query: 1830 EFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCD 1889
            EFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCD
Sbjct: 4370 EFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCD 4429

Query: 1890 CFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHY 1949
            CFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHY
Sbjct: 4430 CFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHY 4489

Query: 1950 VTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVL 2009
            VTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVL
Sbjct: 4490 VTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVL 4549

Query: 2010 IKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRL 2069
            IKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRL
Sbjct: 4550 IKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRL 4609

Query: 2070 PYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTK 2129
            PYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTK
Sbjct: 4610 PYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTK 4669

Query: 2130 RPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGSSL 2189
            RPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGSSL
Sbjct: 4670 RPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGSSL 4729

Query: 2190 ECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNT 2249
            ECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNT
Sbjct: 4730 ECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNT 4789

Query: 2250 VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIIC 2309
            VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIIC
Sbjct: 4790 VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIIC 4849

Query: 2310 QPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKM 2369
            QPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKM
Sbjct: 4850 QPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKM 4909

Query: 2370 VPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPC 2429
            VPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPC
Sbjct: 4910 VPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPC 4969

Query: 2430 NTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKIH 2489
            NTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKIH
Sbjct: 4970 NTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKIH 5029

Query: 2490 NQLISSVSNITCPNFDASICIPGSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGC 2549
            NQLISSVSNITCPNFDASICIPGSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGC
Sbjct: 5030 NQLISSVSNITCPNFDASICIPGSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGC 5089

Query: 2550 TKTVLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEEKTSQREVVLSCPNGGSLTHTYTHI 2609
            TKTVLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEEKTSQREVVLSCPNGGSLTHTYTHI
Sbjct: 5090 TKTVLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEEKTSQREVVLSCPNGGSLTHTYTHI 5149

Query: 2610 ESCQCQDTVCGLPTGTSRRARRSPRHLGSG 2639
            ESCQCQDTVCGLPTGTSRRARRSPRHLGSG
Sbjct: 5150 ESCQCQDTVCGLPTGTSRRARRSPRHLGSG 5179



 Score = 2299 bits (5957), Expect = 0.0
 Identities = 1169/1551 (75%), Positives = 1226/1551 (79%), Gaps = 102/1551 (6%)

Query: 346  KTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQV 405
            KTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQV
Sbjct: 445  KTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQV 504

Query: 406  QLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCH 465
            QLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCH
Sbjct: 505  QLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCH 564

Query: 466  DKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNN 525
            DKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNN
Sbjct: 565  DKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNN 624

Query: 526  EDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEA 585
            EDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEA
Sbjct: 625  EDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEA 684

Query: 586  DSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRD 645
            DSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRD
Sbjct: 685  DSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRD 744

Query: 646  GRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPD 705
            GRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPD
Sbjct: 745  GRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPD 804

Query: 706  GLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYG 765
            GLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYG
Sbjct: 805  GLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYG 864

Query: 766  SGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFM 825
            SGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFM
Sbjct: 865  SGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFM 924

Query: 826  GRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSY 885
            GRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSY
Sbjct: 925  GRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSY 984

Query: 886  KGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRR 945
            KGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRR
Sbjct: 985  KGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRR 1044

Query: 946  SWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTK 1005
            SWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTK
Sbjct: 1045 SWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTK 1104

Query: 1006 EGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCY 1065
            EGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCY
Sbjct: 1105 EGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCY 1164

Query: 1066 PRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPE 1125
            PRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPE
Sbjct: 1165 PRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPE 1224

Query: 1126 EGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTT 1185
            EGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTT
Sbjct: 1225 EGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTT 1284

Query: 1186 TTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDGVCGAPEDIECRSVKDP 1245
            TTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDGVCGAPEDIECRSVKDP
Sbjct: 1285 TTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDGVCGAPEDIECRSVKDP 1344

Query: 1246 HLSLEQLGQKVQLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCC----ECVTQPT 1301
            HLSLEQLGQKVQ  CDVSVG ICKNEDQ   G  P   C +Y+I V CC    +C+T P+
Sbjct: 1345 HLSLEQLGQKVQ--CDVSVGFICKNEDQFGNG--PFGLCYDYKIRVNCCWPMDKCITTPS 1400

Query: 1302 TMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTP 1361
              TTT    P+P P T+TTT+ PT        TTP+P TTTTT   TP PT T +P   P
Sbjct: 1401 PPTTT----PSPPP-TSTTTLPPT--------TTPSPPTTTTT---TPPPTTTPSP---P 1441

Query: 1362 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPT 1421
            ITTTTT  PT TP+   + TTTP  TTT   PT TP+   T  S P TTTTT  PT TP+
Sbjct: 1442 ITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPS 1501

Query: 1422 GTQTPTTTPIT---TTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPIT 1478
                PTTTPIT   +TTT+ PT TP+      PT  TTT   T TP+P     PTTTPIT
Sbjct: 1502 ---PPTTTPITPPASTTTLPPTTTPS-----PPTTTTTTPPPTTTPSP-----PTTTPIT 1548

Query: 1479 TTTTVTPTPTPTGTQTPTPTAITTTTTVTP----TPTPTGTQTPTSTPITTTT---TVTP 1531
              T+ T  P PT T +P PT     TT TP    TP+P  T TP+   ITTTT   T TP
Sbjct: 1549 PPTSTTTLP-PTTTPSPPPT-----TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP 1602

Query: 1532 TPTPTGTQTPTPTPISTTTTVTPTPTPTGTQT--PTTTPI---TTTTTVTPTPTPT-GTQ 1585
            +P  T T TP PT   +  T TP   PT T T  PTTTP    TTTTT  PT TP+  T 
Sbjct: 1603 SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTT 1662

Query: 1586 TPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVT 1645
            T  +  ITTTTT  PT TP+S  +TT +P TTT T   TP+PT T +    PI+TTTT +
Sbjct: 1663 TTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMT---TPSPTTTPSS---PITTTTTPS 1716

Query: 1646 PTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAI 1705
             T TP+     PP  T T P +  TT +PP  + T     +TSSPLT +    S  PP  
Sbjct: 1717 STTTPS-----PPPTTMTTP-SPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTF 1770

Query: 1706 EMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTS 1765
               ST  P+TP  P     G   S  P+       T   G   G   A   S        
Sbjct: 1771 SPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANIS-------- 1822

Query: 1766 AWTPTPTPLSTPSIIRTTGLRPYPSSVL---ICCVLNDTYYAPGEEVYNGTYGDTCYFVN 1822
                           R T     P   L   + C ++       E+   G      + +N
Sbjct: 1823 --------------CRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLN 1868

Query: 1823 CSLS---CTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPP 1870
              ++   C       +  +T +  PTP  +TP  +  + TP+    GT+ P
Sbjct: 1869 YEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTP 1919



 Score =  881 bits (2277), Expect = 0.0
 Identities = 479/743 (64%), Positives = 530/743 (71%), Gaps = 56/743 (7%)

Query: 1158 SITTRPSTLTTFTTITLPTTPTTFTTTT----TTTTPTSSTVLSTTPKLCCL----WSDW 1209
            S TT PS  TT  T   PTT ++  TTT    + T PT S   +TTP   C+    W+ W
Sbjct: 1732 SPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGW 1791

Query: 1210 INEDHPSSGSDDGDRETFDGVCGA--PEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLI 1267
            ++   P+     GD E    VCG     +I CR+   P + + QLGQ V  VCDVSVGLI
Sbjct: 1792 LDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTV--VCDVSVGLI 1849

Query: 1268 CKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTP---TPITTTTTVTP 1324
            CKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTP   TPITTTTTVTP
Sbjct: 1850 CKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTP 1909

Query: 1325 TPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1384
            TPTPT TQ+ T TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP
Sbjct: 1910 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1969

Query: 1385 ITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 1444
            ITTTTTVTPTPTPTGTQTPT+TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT
Sbjct: 1970 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2029

Query: 1445 GTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTT 1504
            GTQ PT T ITTT+TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTT
Sbjct: 2030 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2089

Query: 1505 TVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTP 1564
            TVTPTPTPTGTQTPT+TPITTTTTVTPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTP
Sbjct: 2090 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2149

Query: 1565 TTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTAT 1624
            TTTPITTTTTVTPTPTPTGTQTPTT  ITTTTT+TPTPTPT T++ T TPITTTTTVT T
Sbjct: 2150 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2209

Query: 1625 PTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTS 1684
            PTPTGTQTPT  PI+TTTTVTPTPTPT   T  PT   T PI   TT  P P  +  QT 
Sbjct: 2210 PTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPT---TTPITTTTTVTPTPTPTGTQT- 2263

Query: 1685 RSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR 1744
              T++P+T +TT+  T  P    T T  P+  T P TT+   T +P P+ T +P  TP  
Sbjct: 2264 -PTTTPITTTTTVTPTPTP----TGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPIT 2316

Query: 1745 GTTTGS-----SSAPTPSTVQTTTTSAWTPTPTPLSTPS-----IIRTTGLRPYP----S 1790
             TTT +     +   TP+T   TTT+  TPTPTP  T +     I  TT + P P    +
Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2376

Query: 1791 SVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKST 1850
                   +  T          GT   T   +  + +            TP+PTPT +++ 
Sbjct: 2377 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-----------TPTPTPTGTQTP 2425

Query: 1851 PTPSKPSSTPSKPTP---GTKPP 1870
             T    ++T   PTP   GT+ P
Sbjct: 2426 TTTPITTTTTVTPTPTPTGTQTP 2448



 Score =  731 bits (1887), Expect = 0.0
 Identities = 399/592 (67%), Positives = 433/592 (73%), Gaps = 42/592 (7%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 3715 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3774

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3775 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3834

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3835 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3894

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3895 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3954

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3955 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4014

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 4015 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4074

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 4075 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 4123

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 4124 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4181

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVN-- 1822
            +  TPTPTP  T      TG   + S+  I  +   T   P E     T   T   +   
Sbjct: 4182 TTVTPTPTPTGT-----QTGPPTHTSTAPIAEL--TTSNPPPESSTPQTSRSTSSPLTES 4234

Query: 1823 ----CSLSCTLEFYNWSCPSTP-SPTPTPSKST--PTPSKPSSTPSKPTPGT 1867
                 +L   +E  + + PSTP +PT T    T  P PS  +S P  PT GT
Sbjct: 4235 TTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGT 4286



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 1967 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2026

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2027 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2086

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2087 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2146

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2147 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2206

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2207 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2266

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2267 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2326

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2327 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 2375

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2376 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2433

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 2434 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2493

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 2494 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2540



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2059 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2118

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2119 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2178

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2179 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2238

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2239 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2298

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2299 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2358

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2359 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2418

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2419 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 2467

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2468 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2525

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 2526 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2585

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 2586 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2632



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2151 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2210

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2211 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2270

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2271 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2330

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2331 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2390

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2391 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2450

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2451 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2510

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2511 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 2559

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2560 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2617

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 2618 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2677

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 2678 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2724



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2243 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2302

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2303 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2362

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2363 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2422

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2423 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2482

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2483 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2542

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2543 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2602

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2603 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 2651

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2652 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2709

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 2710 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2769

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 2770 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2816



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2335 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2394

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2395 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2454

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2455 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2514

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2515 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2574

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2575 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2634

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2635 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2694

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2695 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 2743

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2744 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2801

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 2802 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2861

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 2862 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2908



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2427 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2486

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2487 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2546

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2547 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2606

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2607 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2666

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2667 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2726

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2727 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2786

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2787 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 2835

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2836 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2893

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 2894 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2953

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 2954 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3000



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2519 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2578

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2579 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2638

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2698

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2699 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2758

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2759 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2818

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2819 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2878

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2879 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 2927

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2928 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2985

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 2986 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3045

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3046 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3092



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2611 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2670

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2671 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2790

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2791 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2850

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2851 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2910

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2911 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2970

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2971 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 3019

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3020 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3077

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 3078 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3137

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3138 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3184



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2703 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2762

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2763 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2822

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2823 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2882

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2883 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2942

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2943 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3002

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3062

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3063 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 3111

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3112 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3169

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 3170 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3229

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3230 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3276



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2795 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2854

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2855 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2914

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2915 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2974

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2975 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3034

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3035 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3094

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3095 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3154

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3155 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 3203

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3204 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3261

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 3262 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3321

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3322 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3368



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2887 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2946

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2947 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3006

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3007 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3066

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3067 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3126

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3127 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3186

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3187 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3246

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3247 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 3295

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3296 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3353

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 3354 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3413

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3414 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3460



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2979 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3038

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3039 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3098

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3099 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3158

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3159 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3218

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3219 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3278

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3279 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3338

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3339 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 3387

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3388 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3445

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 3446 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3505

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3506 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3552



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 3071 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3130

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3131 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3190

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3191 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3250

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3251 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3310

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3311 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3370

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3431 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 3479

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3480 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3537

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 3538 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3597

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3598 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3644



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 3094 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3153

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3154 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3273

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3274 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3333

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3334 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3393

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3394 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3453

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3454 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3502

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3503 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3560

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYPS----SVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P+           +  T          GT  
Sbjct: 3561 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3620

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + + T           P+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3621 PTTTPITTTTTVT-----------PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3667



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 3117 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3176

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3177 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3236

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3237 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3296

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3297 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3356

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3357 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3416

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3417 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3476

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3477 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3525

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3526 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3583

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYPS----SVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P+           +  T          GT  
Sbjct: 3584 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3643

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + + T           P+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3644 PTTTPITTTTTVT-----------PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3690



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 3163 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3222

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3223 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3282

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3283 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3342

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3343 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3402

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3403 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3462

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3463 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3522

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3523 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 3571

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3572 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3629

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 3630 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3689

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3690 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3736



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 3255 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3314

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3315 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3374

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3434

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3435 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3494

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3495 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3554

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3555 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3614

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3615 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 3663

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3664 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3721

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 3722 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3781

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3782 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3828



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 3347 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3406

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3407 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3466

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3467 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3526

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3527 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3586

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3587 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3646

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3647 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3706

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3707 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 3755

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3756 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3813

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 3814 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3873

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3874 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3920



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 3439 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3498

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3499 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3558

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3559 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3618

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3619 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3678

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3679 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3738

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3739 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3798

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3799 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 3847

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3848 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3905

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 3906 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3965

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3966 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4012



 Score =  730 bits (1884), Expect = 0.0
 Identities = 394/598 (65%), Positives = 432/598 (72%), Gaps = 49/598 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 3531 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3590

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3591 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3650

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3651 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3710

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3711 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3770

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3771 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3830

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3831 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3890

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3891 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 3939

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3940 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3997

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGTYG 1815
            +  TPTPTP  T +     I  TT + P P    +       +  T          GT  
Sbjct: 3998 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4057

Query: 1816 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 4058 PTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4104



 Score =  729 bits (1882), Expect = 0.0
 Identities = 393/594 (66%), Positives = 430/594 (72%), Gaps = 64/594 (10%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 3623 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3682

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3683 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3742

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3743 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3802

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3803 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3862

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3863 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3922

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3923 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3982

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3983 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP----TG 4031

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 4032 TQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4089

Query: 1765 SAWTPTPTPLSTPS-----IIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCY 1819
            +  TPTPTP  T +     I  TT + P P+                     GT   T  
Sbjct: 4090 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-------------------TGTQTPTTT 4130

Query: 1820 FVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 4131 PITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4173



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2013 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2072

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2073 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2132

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2133 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2192

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2193 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2252

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2253 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2312

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2313 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2372

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2373 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2421

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2422 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2479

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2480 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2531

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2532 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2580



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2036 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2095

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2096 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2155

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2156 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2215

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2216 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2275

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2276 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2335

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2336 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2395

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2396 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2444

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2445 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2502

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2503 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2554

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2603



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2082 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2141

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2142 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2201

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2202 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2261

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2262 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2321

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2322 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2382 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2441

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2442 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2490

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2491 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2548

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2549 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2600

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2601 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2649



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2105 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2164

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2165 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2224

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2284

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2285 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2344

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2345 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2404

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2405 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2464

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2465 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2513

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2514 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2571

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2572 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2623

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2624 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2672



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2128 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2187

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2188 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2247

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2248 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2307

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2308 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2367

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2368 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2427

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2428 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2487

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2488 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2536

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2537 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2594

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2595 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2646

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2647 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2695



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2174 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2233

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2234 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2294 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2353

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2354 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2413

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2414 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2473

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2474 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2533

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2534 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2582

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2583 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2640

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2641 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2692

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2693 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2741



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2197 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2256

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2257 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2316

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2376

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2377 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2436

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2437 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2496

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2556

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2557 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2605

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2606 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2663

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2664 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2715

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2716 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2764



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2220 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2279

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2280 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2339

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2340 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2399

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2400 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2459

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2460 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2519

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2520 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2579

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2580 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2628

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2629 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2686

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2687 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2738

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2739 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2787



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2266 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2325

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2326 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2445

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2446 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2505

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2506 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2565

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2566 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2625

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2626 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2674

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2675 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2732

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2733 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2784

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2785 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2833



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2289 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2348

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2349 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2408

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2468

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2469 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2528

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2529 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2588

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2589 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2648

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2649 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2697

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2698 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2755

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2756 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2807

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2808 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2856



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2312 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2371

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2372 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2431

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2432 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2491

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2492 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2551

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2552 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2611

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2672 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2720

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2721 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2778

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2779 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2830

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2831 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2879



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2358 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2417

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2418 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2477

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2478 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2537

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2538 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2597

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2598 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2657

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2658 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2717

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2718 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2766

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2767 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2824

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2825 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2876

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2877 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2925



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2381 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2440

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2441 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2500

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2501 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2560

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2561 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2620

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2621 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2680

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2740

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2741 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2789

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2790 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2847

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2848 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2899

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2948



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2404 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2463

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2464 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2523

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2583

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2584 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2643

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2644 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2703

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2704 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2763

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2764 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2812

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2813 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2870

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2871 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2922

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2923 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2971



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2450 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2509

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2510 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2569

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2570 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2629

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2630 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2689

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2690 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2749

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2750 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2810 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2858

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2859 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2916

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2917 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2968

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2969 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3017



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2473 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2532

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2533 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2592

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2593 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2652

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2653 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2712

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2713 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2772

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2773 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2832

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2833 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2881

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2882 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2939

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2940 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2991

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2992 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3040



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2496 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2555

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2556 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2615

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2616 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2675

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2676 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2735

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2736 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2795

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2796 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2855

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2856 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2904

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2905 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2962

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 2963 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3014

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3063



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2542 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2601

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2602 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2661

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2662 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2721

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2722 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2781

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2782 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2841

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2842 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2901

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2902 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2950

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2951 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3008

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3009 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3060

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3109



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2565 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2624

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2625 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2684

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2685 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2744

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2745 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2804

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2805 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2864

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2865 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2924

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2925 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2973

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2974 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3031

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3032 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3083

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3084 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3132



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2588 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2647

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2648 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2707

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2708 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2767

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2768 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2827

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2828 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2887

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2947

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2948 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 2996

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 2997 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3054

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3055 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3106

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3107 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3155



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2634 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2693

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2694 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2753

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2813

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2814 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2873

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2874 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2993

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 2994 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3042

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3043 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3100

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3101 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3152

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3153 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3201



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2657 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2716

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2717 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2776

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2777 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2836

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2837 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2896

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2897 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2956

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2957 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3016

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3017 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3065

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3066 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3123

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3124 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3175

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3176 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3224



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2680 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2739

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2740 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2799

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2800 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2859

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2860 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2919

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2920 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2979

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 2980 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3039

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3040 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3088

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3089 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3146

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3147 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3198

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3247



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2726 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2785

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2786 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2845

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2846 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2905

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2906 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2965

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2966 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3026 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3085

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3086 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3134

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3135 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3192

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3193 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3244

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3245 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3293



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2749 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2808

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2809 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2868

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2928

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2929 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2988

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 2989 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3048

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3049 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3108

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3109 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3157

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3158 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3215

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3216 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3267

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3268 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3316



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2772 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2831

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2832 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2891

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2892 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2951

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2952 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3011

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3012 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3071

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3072 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3131

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3132 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3180

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3181 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3238

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3239 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3290

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3291 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3339



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2818 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2877

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2878 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2937

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2938 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2997

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 2998 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3057

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3058 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3117

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3118 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3177

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3178 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3226

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3227 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3284

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3285 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3336

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3337 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3385



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2841 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2900

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2901 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2960

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3020

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3021 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3080

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3081 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3140

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3141 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3200

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3201 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3249

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3250 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3307

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3308 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3359

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3360 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3408



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2864 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2923

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2924 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2983

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 2984 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3043

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3044 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3103

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3104 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3163

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3164 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3223

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3224 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3272

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3273 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3330

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3331 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3382

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3383 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3431



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2910 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2969

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2970 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3029

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3030 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3089

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3090 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3149

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3150 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3209

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3210 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3269

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3270 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3318

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3319 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3376

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3377 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3428

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3429 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3477



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2933 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2992

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 2993 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3053 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3112

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3113 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3172

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3173 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3232

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3233 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3292

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3293 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3341

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3342 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3399

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3400 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3451

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3452 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3500



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 2956 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3015

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3016 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3135

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3136 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3195

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3196 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3255

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3315

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3316 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3364

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3365 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3422

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3423 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3474

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3475 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3523



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 3002 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3061

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3062 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3121

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3122 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3181

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3182 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3241

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3242 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3301

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3302 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3361

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3362 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3410

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3411 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3468

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3469 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3520

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3521 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3569



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 3025 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3084

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3085 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3144

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3145 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3204

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3205 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3264

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3265 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3324

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3325 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3384

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3385 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3433

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3434 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3491

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3492 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3543

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3544 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3592



 Score =  728 bits (1878), Expect = 0.0
 Identities = 393/592 (66%), Positives = 429/592 (72%), Gaps = 40/592 (6%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP 1349
            T P T TTT T  PTPT        PITTTTTVTPTPTPT TQ+ T TPITTTTTVTPTP
Sbjct: 3048 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3107

Query: 1350 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPIT 1409
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TPIT
Sbjct: 3108 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3167

Query: 1410 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
            TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGT
Sbjct: 3168 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3227

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
            QTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTV
Sbjct: 3228 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3287

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1589
            TPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT
Sbjct: 3288 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3347

Query: 1590 VLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPT 1649
              ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPT
Sbjct: 3348 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3407

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            PT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T 
Sbjct: 3408 PT--GTQTPT---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TG 3456

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTTTT 1764
            T  P+T   P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   TTT
Sbjct: 3457 TQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3514

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            +  TPTPTP  T +        P  + +     +  T    G +    T   T   V  +
Sbjct: 3515 TTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3566

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
             + T      + P T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 3567 PTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 3615



 Score =  726 bits (1874), Expect = 0.0
 Identities = 422/748 (56%), Positives = 473/748 (63%), Gaps = 72/748 (9%)

Query: 1156 ICSITTRPSTLTTFTTITLPTTPTTFTTTTT-TTTPTSSTVLSTTPKLCCLWSDWINEDH 1214
            I + TT   T T   T T  TTP T TTT T T TPT +   +TTP      +  +    
Sbjct: 1947 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTP 2003

Query: 1215 PSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQK 1274
              +G+              P      +      +    G +      ++           
Sbjct: 2004 TPTGTQ------------TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2051

Query: 1275 PGGVIPMAFCLNYEINVQCCECVTQPTTMTT-----TTTENPTP----------TPITTT 1319
             G   P    +     V      T   T TT     TTT  PTP          TPITTT
Sbjct: 2052 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2111

Query: 1320 TTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 1379
            TTVTPTPTPT TQ+ T TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT
Sbjct: 2112 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2171

Query: 1380 PTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1439
            PTTTPITTTTTVTPTPTPTGTQTPT+TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP
Sbjct: 2172 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2231

Query: 1440 TPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTA 1499
            TPTPTGTQ PT T ITTT+TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT T 
Sbjct: 2232 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2291

Query: 1500 ITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPT 1559
            ITTTTTVTPTPTPTGTQTPT+TPITTTTTVTPTPTPTGTQTPT TPI+TTTTVTPTPTPT
Sbjct: 2292 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2351

Query: 1560 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTT 1619
            GTQTPTTTPITTTTTVTPTPTPTGTQTPTT  ITTTTT+TPTPTPT T++ T TPITTTT
Sbjct: 2352 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2411

Query: 1620 TVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESS 1679
            TVT TPTPTGTQTPT  PI+TTTTVTPTPTPT   T  PT   T PI   TT  P P  +
Sbjct: 2412 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPT---TTPITTTTTVTPTPTPT 2466

Query: 1680 TPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPP 1739
              QT   T++P+T +TT+  T  P    T T  P+  T P TT+   T +P P+ T +P 
Sbjct: 2467 GTQT--PTTTPITTTTTVTPTPTP----TGTQTPT--TTPITTTTTVTPTPTPTGTQTPT 2518

Query: 1740 GTPTRGTTTGS-----SSAPTPSTVQTTTTSAWTPTPTPLSTPS-----IIRTTGLRPYP 1789
             TP   TTT +     +   TP+T   TTT+  TPTPTP  T +     I  TT + P P
Sbjct: 2519 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2578

Query: 1790 ----SSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPT 1845
                +       +  T          GT   T   +  + +            TP+PTPT
Sbjct: 2579 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-----------TPTPTPT 2627

Query: 1846 PSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             +++  T    ++T   PTP   GT+ P
Sbjct: 2628 GTQTPTTTPITTTTTVTPTPTPTGTQTP 2655



 Score =  726 bits (1874), Expect = 0.0
 Identities = 422/748 (56%), Positives = 473/748 (63%), Gaps = 72/748 (9%)

Query: 1156 ICSITTRPSTLTTFTTITLPTTPTTFTTTTT-TTTPTSSTVLSTTPKLCCLWSDWINEDH 1214
            I + TT   T T   T T  TTP T TTT T T TPT +   +TTP      +  +    
Sbjct: 2614 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTP 2670

Query: 1215 PSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQK 1274
              +G+              P      +      +    G +      ++           
Sbjct: 2671 TPTGTQ------------TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2718

Query: 1275 PGGVIPMAFCLNYEINVQCCECVTQPTTMTT-----TTTENPTP----------TPITTT 1319
             G   P    +     V      T   T TT     TTT  PTP          TPITTT
Sbjct: 2719 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2778

Query: 1320 TTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 1379
            TTVTPTPTPT TQ+ T TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT
Sbjct: 2779 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2838

Query: 1380 PTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1439
            PTTTPITTTTTVTPTPTPTGTQTPT+TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP
Sbjct: 2839 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2898

Query: 1440 TPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTA 1499
            TPTPTGTQ PT T ITTT+TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT T 
Sbjct: 2899 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2958

Query: 1500 ITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPT 1559
            ITTTTTVTPTPTPTGTQTPT+TPITTTTTVTPTPTPTGTQTPT TPI+TTTTVTPTPTPT
Sbjct: 2959 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3018

Query: 1560 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTT 1619
            GTQTPTTTPITTTTTVTPTPTPTGTQTPTT  ITTTTT+TPTPTPT T++ T TPITTTT
Sbjct: 3019 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3078

Query: 1620 TVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESS 1679
            TVT TPTPTGTQTPT  PI+TTTTVTPTPTPT   T  PT   T PI   TT  P P  +
Sbjct: 3079 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPT---TTPITTTTTVTPTPTPT 3133

Query: 1680 TPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPP 1739
              QT   T++P+T +TT+  T  P    T T  P+  T P TT+   T +P P+ T +P 
Sbjct: 3134 GTQT--PTTTPITTTTTVTPTPTP----TGTQTPT--TTPITTTTTVTPTPTPTGTQTPT 3185

Query: 1740 GTPTRGTTTGS-----SSAPTPSTVQTTTTSAWTPTPTPLSTPS-----IIRTTGLRPYP 1789
             TP   TTT +     +   TP+T   TTT+  TPTPTP  T +     I  TT + P P
Sbjct: 3186 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3245

Query: 1790 ----SSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPT 1845
                +       +  T          GT   T   +  + +            TP+PTPT
Sbjct: 3246 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-----------TPTPTPT 3294

Query: 1846 PSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             +++  T    ++T   PTP   GT+ P
Sbjct: 3295 GTQTPTTTPITTTTTVTPTPTPTGTQTP 3322



 Score =  726 bits (1874), Expect = 0.0
 Identities = 422/748 (56%), Positives = 473/748 (63%), Gaps = 72/748 (9%)

Query: 1156 ICSITTRPSTLTTFTTITLPTTPTTFTTTTT-TTTPTSSTVLSTTPKLCCLWSDWINEDH 1214
            I + TT   T T   T T  TTP T TTT T T TPT +   +TTP      +  +    
Sbjct: 3281 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTP 3337

Query: 1215 PSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQK 1274
              +G+              P      +      +    G +      ++           
Sbjct: 3338 TPTGTQ------------TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3385

Query: 1275 PGGVIPMAFCLNYEINVQCCECVTQPTTMTT-----TTTENPTP----------TPITTT 1319
             G   P    +     V      T   T TT     TTT  PTP          TPITTT
Sbjct: 3386 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3445

Query: 1320 TTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 1379
            TTVTPTPTPT TQ+ T TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT
Sbjct: 3446 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3505

Query: 1380 PTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1439
            PTTTPITTTTTVTPTPTPTGTQTPT+TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP
Sbjct: 3506 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3565

Query: 1440 TPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTA 1499
            TPTPTGTQ PT T ITTT+TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT T 
Sbjct: 3566 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625

Query: 1500 ITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPT 1559
            ITTTTTVTPTPTPTGTQTPT+TPITTTTTVTPTPTPTGTQTPT TPI+TTTTVTPTPTPT
Sbjct: 3626 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3685

Query: 1560 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTT 1619
            GTQTPTTTPITTTTTVTPTPTPTGTQTPTT  ITTTTT+TPTPTPT T++ T TPITTTT
Sbjct: 3686 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3745

Query: 1620 TVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESS 1679
            TVT TPTPTGTQTPT  PI+TTTTVTPTPTPT   T  PT   T PI   TT  P P  +
Sbjct: 3746 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPT---TTPITTTTTVTPTPTPT 3800

Query: 1680 TPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPP 1739
              QT   T++P+T +TT+  T  P    T T  P+  T P TT+   T +P P+ T +P 
Sbjct: 3801 GTQT--PTTTPITTTTTVTPTPTP----TGTQTPT--TTPITTTTTVTPTPTPTGTQTPT 3852

Query: 1740 GTPTRGTTTGS-----SSAPTPSTVQTTTTSAWTPTPTPLSTPS-----IIRTTGLRPYP 1789
             TP   TTT +     +   TP+T   TTT+  TPTPTP  T +     I  TT + P P
Sbjct: 3853 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3912

Query: 1790 ----SSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPT 1845
                +       +  T          GT   T   +  + +            TP+PTPT
Sbjct: 3913 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-----------TPTPTPT 3961

Query: 1846 PSKSTPTPSKPSSTPSKPTP---GTKPP 1870
             +++  T    ++T   PTP   GT+ P
Sbjct: 3962 GTQTPTTTPITTTTTVTPTPTPTGTQTP 3989



 Score =  715 bits (1846), Expect = 0.0
 Identities = 392/600 (65%), Positives = 430/600 (71%), Gaps = 53/600 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTV--TPTPTPTSTQSTTPTPITTTTTVTP 1347
            T P T TTT T  PTPT        PITTTTTV    TPTPT TQ+ T TPITTTTTVTP
Sbjct: 3209 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTP 3266

Query: 1348 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTP 1407
            TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TP
Sbjct: 3267 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3326

Query: 1408 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPT 1467
            ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPT
Sbjct: 3327 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3386

Query: 1468 GTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTT 1527
            GTQTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTT
Sbjct: 3387 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3446

Query: 1528 TVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1587
            TVTPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP
Sbjct: 3447 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3506

Query: 1588 TTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPT 1647
            TT  ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPT
Sbjct: 3507 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3566

Query: 1648 PTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 1707
            PTPT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    
Sbjct: 3567 PTPT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP---- 3615

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTT 1762
            T T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   T
Sbjct: 3616 TGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3673

Query: 1763 TTSAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGT 1813
            TT+  TPTPTP  T +     I  TT + P P    +       +  T          GT
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3733

Query: 1814 YGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
               T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3734 QTPTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3782



 Score =  715 bits (1846), Expect = 0.0
 Identities = 392/600 (65%), Positives = 430/600 (71%), Gaps = 53/600 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTV--TPTPTPTSTQSTTPTPITTTTTVTP 1347
            T P T TTT T  PTPT        PITTTTTV    TPTPT TQ+ T TPITTTTTVTP
Sbjct: 3232 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTP 3289

Query: 1348 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTP 1407
            TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TP
Sbjct: 3290 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3349

Query: 1408 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPT 1467
            ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPT
Sbjct: 3350 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3409

Query: 1468 GTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTT 1527
            GTQTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTT
Sbjct: 3410 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3469

Query: 1528 TVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1587
            TVTPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP
Sbjct: 3470 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3529

Query: 1588 TTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPT 1647
            TT  ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPT
Sbjct: 3530 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3589

Query: 1648 PTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 1707
            PTPT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    
Sbjct: 3590 PTPT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP---- 3638

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTT 1762
            T T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   T
Sbjct: 3639 TGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3696

Query: 1763 TTSAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGT 1813
            TT+  TPTPTP  T +     I  TT + P P    +       +  T          GT
Sbjct: 3697 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3756

Query: 1814 YGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
               T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3757 QTPTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3805



 Score =  715 bits (1846), Expect = 0.0
 Identities = 392/600 (65%), Positives = 430/600 (71%), Gaps = 53/600 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTV--TPTPTPTSTQSTTPTPITTTTTVTP 1347
            T P T TTT T  PTPT        PITTTTTV    TPTPT TQ+ T TPITTTTTVTP
Sbjct: 3278 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTP 3335

Query: 1348 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTP 1407
            TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TP
Sbjct: 3336 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3395

Query: 1408 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPT 1467
            ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPT
Sbjct: 3396 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3455

Query: 1468 GTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTT 1527
            GTQTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTT
Sbjct: 3456 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3515

Query: 1528 TVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1587
            TVTPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP
Sbjct: 3516 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3575

Query: 1588 TTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPT 1647
            TT  ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPT
Sbjct: 3576 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3635

Query: 1648 PTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 1707
            PTPT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    
Sbjct: 3636 PTPT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP---- 3684

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTT 1762
            T T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   T
Sbjct: 3685 TGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3742

Query: 1763 TTSAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGT 1813
            TT+  TPTPTP  T +     I  TT + P P    +       +  T          GT
Sbjct: 3743 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3802

Query: 1814 YGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
               T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3803 QTPTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3851



 Score =  715 bits (1846), Expect = 0.0
 Identities = 392/600 (65%), Positives = 430/600 (71%), Gaps = 53/600 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTV--TPTPTPTSTQSTTPTPITTTTTVTP 1347
            T P T TTT T  PTPT        PITTTTTV    TPTPT TQ+ T TPITTTTTVTP
Sbjct: 3462 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTP 3519

Query: 1348 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTP 1407
            TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TP
Sbjct: 3520 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3579

Query: 1408 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPT 1467
            ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPT
Sbjct: 3580 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3639

Query: 1468 GTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTT 1527
            GTQTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTT
Sbjct: 3640 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3699

Query: 1528 TVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1587
            TVTPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP
Sbjct: 3700 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3759

Query: 1588 TTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPT 1647
            TT  ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPT
Sbjct: 3760 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3819

Query: 1648 PTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 1707
            PTPT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    
Sbjct: 3820 PTPT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP---- 3868

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTT 1762
            T T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   T
Sbjct: 3869 TGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3926

Query: 1763 TTSAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGT 1813
            TT+  TPTPTP  T +     I  TT + P P    +       +  T          GT
Sbjct: 3927 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3986

Query: 1814 YGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
               T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 3987 QTPTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4035



 Score =  715 bits (1846), Expect = 0.0
 Identities = 392/600 (65%), Positives = 430/600 (71%), Gaps = 53/600 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTV--TPTPTPTSTQSTTPTPITTTTTVTP 1347
            T P T TTT T  PTPT        PITTTTTV    TPTPT TQ+ T TPITTTTTVTP
Sbjct: 3485 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTP 3542

Query: 1348 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTP 1407
            TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TP
Sbjct: 3543 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3602

Query: 1408 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPT 1467
            ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPT
Sbjct: 3603 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3662

Query: 1468 GTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTT 1527
            GTQTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTT
Sbjct: 3663 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3722

Query: 1528 TVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1587
            TVTPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP
Sbjct: 3723 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3782

Query: 1588 TTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPT 1647
            TT  ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPT
Sbjct: 3783 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3842

Query: 1648 PTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 1707
            PTPT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    
Sbjct: 3843 PTPT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP---- 3891

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTT 1762
            T T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   T
Sbjct: 3892 TGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3949

Query: 1763 TTSAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGT 1813
            TT+  TPTPTP  T +     I  TT + P P    +       +  T          GT
Sbjct: 3950 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4009

Query: 1814 YGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
               T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 4010 QTPTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4058



 Score =  715 bits (1846), Expect = 0.0
 Identities = 392/600 (65%), Positives = 430/600 (71%), Gaps = 53/600 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTV--TPTPTPTSTQSTTPTPITTTTTVTP 1347
            T P T TTT T  PTPT        PITTTTTV    TPTPT TQ+ T TPITTTTTVTP
Sbjct: 3508 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTP 3565

Query: 1348 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTP 1407
            TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TP
Sbjct: 3566 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625

Query: 1408 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPT 1467
            ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPT
Sbjct: 3626 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3685

Query: 1468 GTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTT 1527
            GTQTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTT
Sbjct: 3686 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3745

Query: 1528 TVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1587
            TVTPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP
Sbjct: 3746 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3805

Query: 1588 TTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPT 1647
            TT  ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPT
Sbjct: 3806 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3865

Query: 1648 PTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 1707
            PTPT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    
Sbjct: 3866 PTPT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP---- 3914

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTT 1762
            T T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   T
Sbjct: 3915 TGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3972

Query: 1763 TTSAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGT 1813
            TT+  TPTPTP  T +     I  TT + P P    +       +  T          GT
Sbjct: 3973 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4032

Query: 1814 YGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
               T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 4033 QTPTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4081



 Score =  715 bits (1846), Expect = 0.0
 Identities = 392/600 (65%), Positives = 430/600 (71%), Gaps = 53/600 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTV--TPTPTPTSTQSTTPTPITTTTTVTP 1347
            T P T TTT T  PTPT        PITTTTTV    TPTPT TQ+ T TPITTTTTVTP
Sbjct: 3554 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTP 3611

Query: 1348 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTP 1407
            TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TP
Sbjct: 3612 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3671

Query: 1408 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPT 1467
            ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPT
Sbjct: 3672 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3731

Query: 1468 GTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTT 1527
            GTQTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTT
Sbjct: 3732 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3791

Query: 1528 TVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1587
            TVTPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP
Sbjct: 3792 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3851

Query: 1588 TTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPT 1647
            TT  ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPT
Sbjct: 3852 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3911

Query: 1648 PTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 1707
            PTPT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    
Sbjct: 3912 PTPT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP---- 3960

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTT 1762
            T T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   T
Sbjct: 3961 TGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4018

Query: 1763 TTSAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGT 1813
            TT+  TPTPTP  T +     I  TT + P P    +       +  T          GT
Sbjct: 4019 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4078

Query: 1814 YGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
               T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 4079 QTPTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4127



 Score =  715 bits (1846), Expect = 0.0
 Identities = 392/600 (65%), Positives = 430/600 (71%), Gaps = 53/600 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTV--TPTPTPTSTQSTTPTPITTTTTVTP 1347
            T P T TTT T  PTPT        PITTTTTV    TPTPT TQ+ T TPITTTTTVTP
Sbjct: 3577 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTP 3634

Query: 1348 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTP 1407
            TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TP
Sbjct: 3635 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3694

Query: 1408 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPT 1467
            ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPT
Sbjct: 3695 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3754

Query: 1468 GTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTT 1527
            GTQTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTT
Sbjct: 3755 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3814

Query: 1528 TVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1587
            TVTPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP
Sbjct: 3815 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3874

Query: 1588 TTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPT 1647
            TT  ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPT
Sbjct: 3875 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3934

Query: 1648 PTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 1707
            PTPT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    
Sbjct: 3935 PTPT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP---- 3983

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTT 1762
            T T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   T
Sbjct: 3984 TGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4041

Query: 1763 TTSAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGT 1813
            TT+  TPTPTP  T +     I  TT + P P    +       +  T          GT
Sbjct: 4042 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4101

Query: 1814 YGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP---GTKPP 1870
               T   +  + +            TP+PTPT +++  T    ++T   PTP   GT+ P
Sbjct: 4102 QTPTTTPITTTTTV-----------TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4150



 Score =  715 bits (1846), Expect = 0.0
 Identities = 393/611 (64%), Positives = 433/611 (70%), Gaps = 53/611 (8%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTV--TPTPTPTSTQSTTPTPITTTTTVTP 1347
            T P T TTT T  PTPT        PITTTTTV    TPTPT TQ+ T TPITTTTTVTP
Sbjct: 3646 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTP 3703

Query: 1348 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTP 1407
            TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TP
Sbjct: 3704 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3763

Query: 1408 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPT 1467
            ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPT
Sbjct: 3764 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3823

Query: 1468 GTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTT 1527
            GTQTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTT
Sbjct: 3824 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3883

Query: 1528 TVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1587
            TVTPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP
Sbjct: 3884 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3943

Query: 1588 TTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPT 1647
            TT  ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPT
Sbjct: 3944 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4003

Query: 1648 PTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 1707
            PTPT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    
Sbjct: 4004 PTPT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP---- 4052

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTT 1762
            T T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   T
Sbjct: 4053 TGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4110

Query: 1763 TTSAWTPTPTPLSTPS-----IIRTTGLRPYP----SSVLICCVLNDTYYAPGEEVYNGT 1813
            TT+  TPTPTP  T +     I  TT + P P    +       +  T          GT
Sbjct: 4111 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4170

Query: 1814 YGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECP 1873
               T   +  + +            TP+PTPT +++ P P+  S+ P      + PP  P
Sbjct: 4171 QTPTTTPITTTTTV-----------TPTPTPTGTQTGP-PTHTSTAPIAELTTSNPP--P 4216

Query: 1874 DFDPPRQENET 1884
            +   P+    T
Sbjct: 4217 ESSTPQTSRST 4227



 Score =  715 bits (1845), Expect = 0.0
 Identities = 394/612 (64%), Positives = 430/612 (70%), Gaps = 60/612 (9%)

Query: 1298 TQPTTMTTTTTENPTPT--------PITTTTTV--TPTPTPTSTQSTTPTPITTTTTVTP 1347
            T P T TTT T  PTPT        PITTTTTV    TPTPT TQ+ T TPITTTTTVTP
Sbjct: 3669 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTP 3726

Query: 1348 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTP 1407
            TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT+TP
Sbjct: 3727 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3786

Query: 1408 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPT 1467
            ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPT
Sbjct: 3787 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3846

Query: 1468 GTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTT 1527
            GTQTPTTTPITTTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTT
Sbjct: 3847 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3906

Query: 1528 TVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1587
            TVTPTPTPTGTQTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP
Sbjct: 3907 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3966

Query: 1588 TTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPT 1647
            TT  ITTTTT+TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPT
Sbjct: 3967 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4026

Query: 1648 PTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 1707
            PTPT   T  PT   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    
Sbjct: 4027 PTPT--GTQTPT---TTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTP---- 4075

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS-----SSAPTPSTVQTT 1762
            T T  P+  T P TT+   T +P P+ T +P  TP   TTT +     +   TP+T   T
Sbjct: 4076 TGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4133

Query: 1763 TTSAWTPTPTPLSTPS-----IIRTTGLRPYP----------SSVLICCVLNDTYYAPGE 1807
            TT+  TPTPTP  T +     I  TT + P P          + +     +  T    G 
Sbjct: 4134 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4193

Query: 1808 EVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSST------PS 1861
            +    T+  T      +          S P   S TP  S+ST +P   S+T      P+
Sbjct: 4194 QTGPPTHTSTAPIAELTT---------SNPPPESSTPQTSRSTSSPLTESTTLLSTLPPA 4244

Query: 1862 KPTPGTKPPECP 1873
                 T PP  P
Sbjct: 4245 IEMTSTAPPSTP 4256



 Score =  697 bits (1799), Expect = 0.0
 Identities = 332/343 (96%), Positives = 332/343 (96%), Gaps = 5/343 (1%)

Query: 1   MGLPLARLAAVCLALSLAGGSELQTEGRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCD 60
           MGLPLARLAAVCLALSLAGGSELQTEGRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCD
Sbjct: 1   MGLPLARLAAVCLALSLAGGSELQTEGRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCD 60

Query: 61  YNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTP 120
           YNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTP
Sbjct: 61  YNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTP 120

Query: 121 HYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSE 180
           HYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSE
Sbjct: 121 HYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSE 180

Query: 181 FLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDL 240
           FLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDL
Sbjct: 181 FLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDL 240

Query: 241 VPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTC 300
           VPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTAT        KTC
Sbjct: 241 VPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATL-----CPKTC 295

Query: 301 PGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGAQAD 343
           PGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEG   D
Sbjct: 296 PGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYD 338



 Score =  589 bits (1518), Expect = e-167
 Identities = 329/518 (63%), Positives = 358/518 (69%), Gaps = 73/518 (14%)

Query: 1359 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTP 1418
            T P T TTT T  PTP     PTTTPITTTTTVTPTPTPTGTQTPT+TPITTTTTVTPTP
Sbjct: 1880 TQPTTMTTTTTENPTP-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1934

Query: 1419 TPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPIT 1478
            TPTGTQTPTTTPITTTTTVTPTPTPTGTQ PT T ITTT+TVTPTPTPTGTQTPTTTPIT
Sbjct: 1935 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1994

Query: 1479 TTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGT 1538
            TTTTVTPTPTPTGTQTPT T ITTTTTVTPTPTPTGTQTPT+TPITTTTTVTPTPTPTGT
Sbjct: 1995 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2054

Query: 1539 QTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTM 1598
            QTPT TPI+TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT  ITTTTT+
Sbjct: 2055 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2114

Query: 1599 TPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPP 1658
            TPTPTPT T++ T TPITTTTTVT TPTPTGTQTPT  PI+TTTTVTPTPTPT   T  P
Sbjct: 2115 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTP 2172

Query: 1659 THTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTA 1718
            T   T PI   TT  P P  +  QT   T++P+T +TT+  T  P    T T  P+T   
Sbjct: 2173 T---TTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP----TGTQTPTT--T 2221

Query: 1719 PTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPS 1778
            P TT+   T +P P+ T +P  TP   TTT +   PTP     T T   TPT TP++T  
Sbjct: 2222 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---PTP-----TPTGTQTPTTTPITT-- 2271

Query: 1779 IIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPS 1838
               TT + P P+                     GT   T                 + P 
Sbjct: 2272 ---TTTVTPTPTPT-------------------GTQTPT-----------------TTPI 2292

Query: 1839 TPSPTPTPSKSTPTPS---KPSSTPSKPTPGTKPPECP 1873
            T + T TP   TPTP+    P++TP   T    P   P
Sbjct: 2293 TTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP 2327



 Score =  338 bits (867), Expect = 4e-92
 Identities = 254/615 (41%), Positives = 303/615 (49%), Gaps = 117/615 (19%)

Query: 1300 PTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTP---TPTPTGTQT 1356
            PTT TTT     TP+P TTT    PT T T   +TTP+P  TTTT  P   TP+P  T T
Sbjct: 1605 PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1664

Query: 1357 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTSTPITTTTTVT 1415
            P+  PITTTTT  PT TP+   T T +P TTT TT +PT TP+   T T+TP ++TTT +
Sbjct: 1665 PSP-PITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTP-SSTTTPS 1722

Query: 1416 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTP--TGTQTPT 1473
            P PT   T +PTTTP   TTT+T  P PT T +P  T     S   PT +P  T T T  
Sbjct: 1723 PPPTTMTTPSPTTTPSPPTTTMTTLP-PTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP 1781

Query: 1474 TTPITTTTTVTPTPTPTGTQTPTPTA-------------ITTTTTVTPTPTPTGT--QTP 1518
              P+   T    +  P   +    T              I+   T+ P   P G   QT 
Sbjct: 1782 CVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPD-VPIGQLGQTV 1840

Query: 1519 TSTPITTTTTVTPTPTPTGTQ-----------------TPTPTPISTTTTVTPTPTPTGT 1561
                            P G                      PT ++TTTT  PTP     
Sbjct: 1841 VCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTP----- 1895

Query: 1562 QTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTV 1621
              PTTTPITTTTTVTPTPTPTGTQTPTT  ITTTTT+TPTPTPT T++ T TPITTTTTV
Sbjct: 1896 --PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1953

Query: 1622 TATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTP 1681
            T TPTPTGTQTPT  PI+TTTTVTPTPTPT   T  PT   T PI   TT  P P  +  
Sbjct: 1954 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT--GTQTPT---TTPITTTTTVTPTPTPTGT 2008

Query: 1682 QTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGT 1741
            QT   T++P+T +TT+  T  P    T T  P+T   P TT+   T +P P+ T +P  T
Sbjct: 2009 QTP--TTTPITTTTTVTPTPTP----TGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTT 2060

Query: 1742 PTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDT 1801
            P   TTT +   PTP     T T   TPT TP++T     TT + P P+           
Sbjct: 2061 PITTTTTVT---PTP-----TPTGTQTPTTTPITT-----TTTVTPTPTPT--------- 2098

Query: 1802 YYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPS---KPSS 1858
                      GT   T                 + P T + T TP   TPTP+    P++
Sbjct: 2099 ----------GTQTPT-----------------TTPITTTTTVTP---TPTPTGTQTPTT 2128

Query: 1859 TPSKPTPGTKPPECP 1873
            TP   T    P   P
Sbjct: 2129 TPITTTTTVTPTPTP 2143



 Score =  297 bits (760), Expect = 1e-79
 Identities = 214/505 (42%), Positives = 254/505 (50%), Gaps = 69/505 (13%)

Query: 1156 ICSITTRPSTLTTFTTITLPTTPTTFTTTTT-TTTPTSSTVLSTTPKLCCLWSDWINEDH 1214
            I + TT   T T   T T  TTP T TTT T T TPT +   +TTP      +  +    
Sbjct: 3948 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTP 4004

Query: 1215 PSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQK 1274
              +G+              P      +      +    G +      ++           
Sbjct: 4005 TPTGTQ------------TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4052

Query: 1275 PGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQST 1334
             G   P    +     V      T   T TTT        PITTTTTVTPTPTPT TQ+ 
Sbjct: 4053 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--------PITTTTTVTPTPTPTGTQTP 4104

Query: 1335 TPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1394
            T TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT
Sbjct: 4105 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4164

Query: 1395 PTPTGTQTPTSTPITTTTTVTPTPTPTGTQT--PT---TTPITTTTTVTPTP------TP 1443
            PTPTGTQTPT+TPITTTTTVTPTPTPTGTQT  PT   T PI   TT  P P      T 
Sbjct: 4165 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTS 4224

Query: 1444 TGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTT----TVTPTPTPTGTQTPTPTA 1499
              T +P   + T  ST+ P    T T  P+T    TTT    T++P P+ T +   TPT 
Sbjct: 4225 RSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR 4284

Query: 1500 ITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPT 1559
             TTT + +  PTP+  QT      TTT+  TPTPTP  T +     I  TT + P P   
Sbjct: 4285 GTTTGS-SSAPTPSTVQT------TTTSAWTPTPTPLSTPS-----IIRTTGLRPYP--- 4329

Query: 1560 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTT-----------MTPTPTPTSTK 1608
             +       +  T          GT   T   +  + +            TP+PTPT +K
Sbjct: 4330 -SSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSK 4388

Query: 1609 STTVTPITTTTTVTATPTPTGTQTP 1633
            ST  TP   ++T  + PTP GT+ P
Sbjct: 4389 STP-TPSKPSST-PSKPTP-GTKPP 4410



 Score =  224 bits (572), Expect = 7e-58
 Identities = 172/444 (38%), Positives = 208/444 (46%), Gaps = 77/444 (17%)

Query: 1449 PTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTP 1508
            P    ITT S  T TP+P  T T T  P     T TP+P  T T TP PT  T +  +T 
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPP-----TTTPSPPTTTTTTPPPTT-TPSPPITT 1444

Query: 1509 TPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTP 1568
            T TP  T TP S PI+TTTT  PT TP+    PT TP   TTT +P  T T T  PTTTP
Sbjct: 1445 TTTPPPTTTP-SPPISTTTTPPPTTTPS---PPTTTPSPPTTTPSPPTTTTTTPPPTTTP 1500

Query: 1569 ITTTTTVTPTPTPTGTQTPTTVL---ITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATP 1625
               TTT    P  T T  PTT      TTTTT  PT TP+   +T +TP T+TTT+  T 
Sbjct: 1501 SPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1560

Query: 1626 TPTGTQTPTMIPISTTT-----TVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESST 1680
            TP+   T T  P  TTT     T TP+P   T +T PPT T + P    TT+ PPP ++ 
Sbjct: 1561 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT--TTTTPPPTTTP 1618

Query: 1681 PQTSRSTSSPLTESTTLLSTL---PPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTS 1737
               + +  +P T +TTL  T    PP    T+  P +TP+ PTTT    T SPP +TTT+
Sbjct: 1619 SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTT----TPSPPITTTTT 1674

Query: 1738 PPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCV 1797
            PP T    TT  S    TPS   TT T     TP+P +TPS   TT   P  ++      
Sbjct: 1675 PPPT----TTPSSPITTTPSPPTTTMT-----TPSPTTTPSSPITTTTTPSSTT------ 1719

Query: 1798 LNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPT----P 1853
               T   P   +                            +TPSPT TPS  T T    P
Sbjct: 1720 ---TPSPPPTTM----------------------------TTPSPTTTPSPPTTTMTTLP 1748

Query: 1854 SKPSSTPSKPTPGTKPPECPDFDP 1877
               +S+P   TP       P F P
Sbjct: 1749 PTTTSSPLTTTPLPPSITPPTFSP 1772



 Score =  220 bits (561), Expect = 1e-56
 Identities = 161/535 (30%), Positives = 241/535 (45%), Gaps = 83/535 (15%)

Query: 637  QEERCVCRDG-RLHCRQIRLIGQSC-----------TAPKIHMDC-SNLTALATSKPRAL 683
            Q++RC C  G    C  +    + C           TA      C  NL  L +  P   
Sbjct: 251  QQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMD 310

Query: 684  SCQTLAAGYYHTEC-VSGCVCPDGLMDD--GRGGCVVEKECPCVHNNDLYSSGAKIKVDC 740
            +C  L       E  + GC CP+G + D  G  GCV   +C C  +  LY+ G +I  DC
Sbjct: 311  TCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITNDC 370

Query: 741  NTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGS 800
              C C  GRWVC    C GTC++ G  H  TFDGK Y F G C YV  +   G ++   S
Sbjct: 371  EQCVCNAGRWVCKDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAK---GDHND--S 425

Query: 801  FSIITENVPCGTTG-VTCSKAIKIFMGRTELKLEDKHRVVIQRDEGH-----------HV 848
            ++++ E  PCG+T   TC K +        L  + K  VV+ + +G            HV
Sbjct: 426  YALLGELAPCGSTDKQTCLKTV-------VLLADKKKNVVVFKSDGSVLLNELQVNLPHV 478

Query: 849  AYT---TREVGQYLVVESSTGI--IVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 903
              +    R    +++V  + G+   V       +F+ L  + +G V GLCGNF+    +D
Sbjct: 479  TASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDD 538

Query: 904  FTTRDHMVVSSELDFGNSWKEAPTCPD-VSTNPEPCSLNPHRRSWAEKQCSILK--SSVF 960
            F T   +V ++   F N+WK   +C D +    +PCSLN    ++AE  CS+LK   + F
Sbjct: 539  FKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPF 598

Query: 961  SICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCP 1019
              CHS VDP  +Y+ C +D+C+C    D  C C+A++SYA+ CT +G  ++ WR      
Sbjct: 599  GRCHSAVDPAEYYKRCKYDTCNCQNNED--CLCAALSSYARACTAKGVMLWGWR------ 650

Query: 1020 IFCDYYNPPHECEWHYEPCGNRSF---------ETCRTINGIHSNISVSY--LEGCYPRC 1068
                     H C      C N            +TCR+++   S+    +  ++GC   C
Sbjct: 651  --------EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGC--GC 700

Query: 1069 PKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCR 1123
            P     + ++  +CV   KC CY    +   G  V  +E  + CVC    ++ CR
Sbjct: 701  PDH--TFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE--ERCVC-RDGRLHCR 750



 Score =  196 bits (498), Expect = 3e-49
 Identities = 145/386 (37%), Positives = 180/386 (46%), Gaps = 85/386 (22%)

Query: 1494 TPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVT 1553
            TP+P     TTT +P PT T T  PT+TP   TTT T   TP  T TP+P PI+TTTT  
Sbjct: 1398 TPSPP----TTTPSPPPTSTTTLPPTTTPSPPTTTTT---TPPPTTTPSP-PITTTTTPP 1449

Query: 1554 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVT 1613
            PT TP+   + TTTP  TTT   PT TP+   T  +   TTTTT  PT TP+   +T +T
Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1509

Query: 1614 PITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSN 1673
            P  +TTT+  T TP+   T T  P  TTT   PT TP T    PPT T+T P    TT +
Sbjct: 1510 PPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT----PPTSTTTLP--PTTTPS 1563

Query: 1674 PPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPS 1733
            PPP ++T     +T SP T +T      PP I  T+  P +TP+ PTTT    T +PPP+
Sbjct: 1564 PPPTTTTTPPPTTTPSPPTTTTPS----PPTITTTTPPPTTTPSPPTTT----TTTPPPT 1615

Query: 1734 TTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVL 1793
            TT SPP T             TP T  T+TT     T  P +TPS   TT   P P++  
Sbjct: 1616 TTPSPPTT-------------TPITPPTSTT-----TLPPTTTPSPPPTTTTTPPPTTT- 1656

Query: 1794 ICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPT-PTPSKSTPT 1852
                                                       PS P+ T P+P  +T T
Sbjct: 1657 -------------------------------------------PSPPTTTTPSPPITTTT 1673

Query: 1853 PSKPSSTPSKPTPGTKPPECPDFDPP 1878
               P++TPS P   T  P       P
Sbjct: 1674 TPPPTTTPSSPITTTPSPPTTTMTTP 1699



 Score =  179 bits (453), Expect = 4e-44
 Identities = 133/360 (36%), Positives = 164/360 (45%), Gaps = 81/360 (22%)

Query: 1520 STPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1579
            +TP   TTT +P PT T T  PT TP   TTT T TP PT T +P   PITTTTT  PT 
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTT-TPPPTTTPSP---PITTTTTPPPTT 1452

Query: 1580 TPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPIS 1639
            TP+   + TT    TTT   PT TP+   +T   P TTTTT   T TP+   T  + P +
Sbjct: 1453 TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPA 1512

Query: 1640 TTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLS 1699
            +TTT+ PT TP+     PPT T+T P    T S P     TP TS +T  P T  +    
Sbjct: 1513 STTTLPPTTTPS-----PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS---- 1563

Query: 1700 TLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTV 1759
              PP    T+  P +TP+ PTTT    T SPP  TTT+PP T T          P+P T 
Sbjct: 1564 --PPPTTTTTPPPTTTPSPPTTT----TPSPPTITTTTPPPTTT----------PSPPTT 1607

Query: 1760 QTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCY 1819
             TTT       P P +TPS   TT + P  S+  +                         
Sbjct: 1608 TTTT-------PPPTTTPSPPTTTPITPPTSTTTL------------------------- 1635

Query: 1820 FVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGT-KPPECPDFDPP 1878
                             P T +P+P P+ +T  P  P++TPS PT  T  PP      PP
Sbjct: 1636 -----------------PPTTTPSPPPTTTTTPP--PTTTPSPPTTTTPSPPITTTTTPP 1676



 Score =  140 bits (352), Expect = 2e-32
 Identities = 118/466 (25%), Positives = 199/466 (42%), Gaps = 63/466 (13%)

Query: 1888 CDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDP 1947
            C C      Y++  +I KV+C      TC  G            C    C   C+ +G  
Sbjct: 820  CPCVHNNDLYSSGAKI-KVDCNTC---TCKRGRW---------VCTQAVCHGTCSIYGSG 866

Query: 1948 HYVTFDGLYYSYQGNCTYVLVEEI---SPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHE 2004
            HY+TFDG YY + G+C+YV V++    + S+ +F +  +N  C     V+C + + +   
Sbjct: 867  HYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTG-VTCSKAIKIFMG 925

Query: 2005 TQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLS 2064
              E+ ++  H + +Q   +     VA   ++ G         Y+V     G++V ++  +
Sbjct: 926  RTELKLEDKHRVVIQ---RDEGHHVAYTTREVG--------QYLVVESSTGIIVIWDKRT 974

Query: 2065 FSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHS 2124
                     +     G CG   + +++D       +VS+     + W       P CP  
Sbjct: 975  TVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSW----KEAPTCPDV 1030

Query: 2125 SSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFM 2184
            S        T P      PH+       C ++K S+F+ CH+ V P+ +Y+ACV DSC  
Sbjct: 1031 S--------TNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSC 1082

Query: 2185 -PGSSLE--CASLQAYAALCAQQNICLDWRNHTHGACLVEC----PSHR---EYQACGPA 2234
              G   E  C+++ +YA  C ++  C+ WR  T   C + C    P H     Y+ CG  
Sbjct: 1083 DTGGDCECFCSAVASYAQECTKEGACVFWR--TPDLCPIFCDYYNPPHECEWHYEPCGNR 1140

Query: 2235 EEPTCKSSSSQQNNTVL--VEGCF--CPEGTMNYAPGFDVCVKT--CGCVGPD-NVPREF 2287
               TC++ +   +N  +  +EGC+  CP+    Y      CV    CGC   D + P   
Sbjct: 1141 SFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGA 1200

Query: 2288 GEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEV 2333
                E  CK+CVC    S ++C+P+   +  + +  +DG +   E+
Sbjct: 1201 SVPTEETCKSCVC-TNSSQVVCRPE---EGKILNQTQDGAFCYWEI 1242



 Score =  140 bits (352), Expect = 2e-32
 Identities = 118/466 (25%), Positives = 199/466 (42%), Gaps = 63/466 (13%)

Query: 721  CPCVHNNDLYSSGAKI-KVDCNTC---TCKRGRW---------VCTQAVCHGTCSIYGSG 767
            C C      Y++  +I KV+C      TC  G            C    C   C+ +G  
Sbjct: 4428 CDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDP 4487

Query: 768  HYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTG-VTCSKAIKIFMG 826
            HY+TFDG YY + G+C+YV V++    + S+ +F +  +N  C     V+C + + +   
Sbjct: 4488 HYVTFDGLYYSYQGNCTYVLVEEI---SPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHE 4544

Query: 827  RTELKLEDKHRVVIQ---RDEGHHVAYTTREVG--------QYLVVESSTGIIVIWDKRT 875
              E+ ++  H + +Q   +     VA   ++ G         Y+V     G++V ++  +
Sbjct: 4545 TQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLS 4604

Query: 876  TVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSW----KEAPTCPDV 931
                     +     G CG   + +++D       +VS+     + W       P CP  
Sbjct: 4605 FSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHS 4664

Query: 932  S--------TNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSC 983
            S        T P      PH+       C ++K S+F+ CH+ V P+ +Y+ACV DSC  
Sbjct: 4665 SSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFM 4724

Query: 984  DTGGDCECFCSAVASYAQECTKEGACVFWR--TPDLCPIFCDYYNPPHECEWHYEPCGNR 1041
              G   E  C+++ +YA  C ++  C+ WR  T   C + C    P H     Y+ CG  
Sbjct: 4725 -PGSSLE--CASLQAYAALCAQQNICLDWRNHTHGACLVEC----PSHR---EYQACGPA 4774

Query: 1042 SFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGA 1101
               TC++ +   +N  +  +EGC+  CP+    Y      CV    CGC   D + P   
Sbjct: 4775 EEPTCKSSSSQQNNTVL--VEGCF--CPEGTMNYAPGFDVCVKT--CGCVGPD-NVPREF 4827

Query: 1102 SVPTEETCKSCVC-TNSSQVVCRPE---EGKILNQTQDGAFCYWEI 1143
                E  CK+CVC    S ++C+P+   +  + +  +DG +   E+
Sbjct: 4828 GEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEV 4873



 Score =  127 bits (319), Expect = 1e-28
 Identities = 100/376 (26%), Positives = 163/376 (43%), Gaps = 36/376 (9%)

Query: 758  HGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTC 817
            H  CS +G+ HY TFDG  + F G C Y    D  G   S   F++  +  P        
Sbjct: 34   HNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAG 90

Query: 818  SKAIKIFMGRTELKLEDKHRVVIQ----RDEGHHVAYTTREVGQYLVVESSTGIIVIWDK 873
             ++I + +    + L  +H  V+         +       +   Y  V S  G+ ++W++
Sbjct: 91   VESILLTIKDDTIYL-TRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNR 149

Query: 874  RTTVFIKLAPSYKGTVCGLCGNFDH-RSNNDFTTRDHMVVSSELDFGNSWK---EAPTCP 929
               + ++L   ++   CGLCG+++  +S ++F +    V+ S L+FGN  K       C 
Sbjct: 150  EDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDG--VLFSPLEFGNMQKINQPDVVCE 207

Query: 930  DVSTNPEPCSLNPHRRSWAEKQCS-ILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGD 988
            D      P S + HR      +C  +L +  F+ C   V  +P+  AC  D C C  GGD
Sbjct: 208  DPEEEVAPASCSEHR-----AECERLLTAEAFADCQDLVPLEPYLRACQQDRCRC-PGGD 261

Query: 989  CECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1047
              C CS VA ++++C+  G     WRT  LCP  C            Y   G+   +TC 
Sbjct: 262  -TCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTC-------PGNLVYLESGSPCMDTCS 313

Query: 1048 TINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEE 1107
             +  + S      ++GC+  CP+     +     CV   +C C +    Y PG  +  + 
Sbjct: 314  HLE-VSSLCEEHRMDGCF--CPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITND- 369

Query: 1108 TCKSCVCTNSSQVVCR 1123
             C+ CVC N+ + VC+
Sbjct: 370  -CEQCVC-NAGRWVCK 383



 Score =  114 bits (286), Expect = 1e-24
 Identities = 87/318 (27%), Positives = 141/318 (44%), Gaps = 21/318 (6%)

Query: 341 QADLPKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIG 400
           QA+ P  V  +    K+  ++ +    +LN   V+ PH +    + +  +Y  + S A G
Sbjct: 84  QAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA-G 142

Query: 401 VRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKA 460
           + L       + L   LD   +    GLCG++NGL+      + G++ +    F N  K 
Sbjct: 143 LTLMWNREDALML--ELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSP-LEFGNMQKI 199

Query: 461 QSSCHDKLDWLDDPCSLNIESANYAEHW--CSLLKKTETPFGRCHSAVDPAEYYKRCKYD 518
                   D + +     +  A+ +EH   C  L   E  F  C   V    Y + C+ D
Sbjct: 200 NQP-----DVVCEDPEEEVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQD 253

Query: 519 TCNCQNNEDCLCAALSSYARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQ 577
            C C   + C+C+ ++ ++R C+  G     WR   +C K   +CP + V+L + + C  
Sbjct: 254 RCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPK---TCPGNLVYLESGSPCMD 310

Query: 578 TCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKG--RCVPLAKCSCYHRGLYLEAGDVVV 635
           TC  L E  S C E    +DGC CP+ T  D+ G   CVP+++C C   G     G  + 
Sbjct: 311 TCSHL-EVSSLCEE--HRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEIT 367

Query: 636 RQEERCVCRDGRLHCRQI 653
              E+CVC  GR  C+ +
Sbjct: 368 NDCEQCVCNAGRWVCKDL 385



 Score =  114 bits (285), Expect = 1e-24
 Identities = 122/519 (23%), Positives = 195/519 (37%), Gaps = 55/519 (10%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C    C   C   G  H  TFDG  Y++ G+C YVL +      D++ +  +   C   D
Sbjct: 382  CKDLPCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAK--GDHNDSYALLGELAPCGSTD 439

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
            K +C +T+++  + +    K V +      V +N   V LP+      V++    +++  
Sbjct: 440  KQTCLKTVVLLADKK----KNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVS 495

Query: 2052 PELGVLVSYN---GLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA 2108
              +GV +       +   V L     G   +G CG       DD    SG + +     A
Sbjct: 496  MAIGVRLQVQLAPVMQLFVTLDQASQG-QVQGLCGNFNGLEGDDFKTASGLVEATGAGFA 554

Query: 2109 DQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIK--DSLFAQCHA 2166
            + W     ++  C         P            H        C L+K  ++ F +CH+
Sbjct: 555  NTW----KAQSSCHDKLDWLDDPCSLNIESANYAEH-------WCSLLKKTETPFGRCHS 603

Query: 2167 LVPPQHYYDACVFDSC-FMPGSSLECASLQAYAALCAQQNICL-DWRNHTHGACLVECPS 2224
             V P  YY  C +D+C         CA+L +YA  C  + + L  WR H     +  CP+
Sbjct: 604  AVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPN 663

Query: 2225 HREYQACGPAEEPTCKSSSSQQNNTV----LVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 2280
             + +       + TC+S S   ++ +     V+GC CP+ T     G  V +  C C   
Sbjct: 664  SQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCY-H 722

Query: 2281 DNVPREFGEHFEFDCKNCVCLEGGSGIICQPKR-----CSQKPVTHCVEDGTYLATEVNP 2335
              +  E G+      + CVC +G   + C+  R     C+   +     + T LAT    
Sbjct: 723  RGLYLEAGDVVVRQEERCVCRDG--RLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPR 780

Query: 2336 ADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQP 2395
            A +C  +     +T        VCP G     +   G C      E +  CVH N  Y  
Sbjct: 781  ALSCQTLAAGYYHTECV--SGCVCPDGLMDDGR---GGCV----VEKECPCVHNNDLYSS 831

Query: 2396 GSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434
            G+ +    C  C C              CT   C+ +CS
Sbjct: 832  GAKI-KVDCNTCTCK--------RGRWVCTQAVCHGTCS 861



 Score = 96.3 bits (238), Expect = 4e-19
 Identities = 87/337 (25%), Positives = 143/337 (42%), Gaps = 32/337 (9%)

Query: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKE-FAVHLKRGP-GQAEAPAGVESI 94
           C+  G  H  TFDG  + F G C Y  A   +G + + +A+  +  P G  +    ++++
Sbjct: 391 CALEGGSHITTFDGKTYTFHGDCYYVLA---KGDHNDSYALLGELAPCGSTDKQTCLKTV 447

Query: 95  LLTI---KDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA-GLTLMWNRE 150
           +L     K+  ++ +    +LN   V+ PH +    + +  +Y  + S A G+ L     
Sbjct: 448 VLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLA 507

Query: 151 DALML--ELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSP-LEFGNMQKINQPDVVCE 207
             + L   LD   +    GLCG++NGL+      + G++ +    F N  K       C 
Sbjct: 508 PVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSS---CH 564

Query: 208 DPEE--------EVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCP 258
           D  +         +  A+ +EH   C  L   E  F  C   V    Y + C+ D C C 
Sbjct: 565 DKLDWLDDPCSLNIESANYAEHW--CSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQ 622

Query: 259 GGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCS 318
             + C+C+ ++ ++R C+  G     WR        G   +CP + V+L + + C  TC 
Sbjct: 623 NNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVG---SCPNSQVFLYNLTTCQQTCR 679

Query: 319 HL-EVSSLCEE--HRMDGCFCPEGAQADLPKTVVLLA 352
            L E  S C E    +DGC CP+    D     V LA
Sbjct: 680 SLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLA 716



 Score = 96.3 bits (238), Expect = 4e-19
 Identities = 91/346 (26%), Positives = 148/346 (42%), Gaps = 41/346 (11%)

Query: 34   HNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAG 90
            H  CS +G+ HY TFDG  + F G C Y    D  G   S   F++  +  P        
Sbjct: 857  HGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTC 916

Query: 91   VESILLTIKDDTIYL-TRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNR 149
             ++I + +    + L  +H  V+         +       +   Y  V S  G+ ++W++
Sbjct: 917  SKAIKIFMGRTELKLEDKHRVVIQ----RDEGHHVAYTTREVGQYLVVESSTGIIVIWDK 972

Query: 150  EDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDG--VLFSPLEFGNMQKINQPDVVCE 207
               + ++L   ++   CGLCG+++  +S ++F +    V+ S L+FGN  K       C 
Sbjct: 973  RTTVFIKLAPSYKGTVCGLCGNFDH-RSNNDFTTRDHMVVSSELDFGNSWK---EAPTCP 1028

Query: 208  DPEEEVAPASCSEHR-----AECERLLTAEAFADCQDLVPLEPYLRACQQDRCRC-PGGD 261
            D      P S + HR      +C  +L +  F+ C   V  +P+  AC  D C C  GGD
Sbjct: 1029 DVSTNPEPCSLNPHRRSWAEKQCS-ILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGD 1087

Query: 262  -TCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSP------GASKTCPGNLVYLESGSPCM 314
              C CS VA ++++C+  G     WRT    + P           C  +  Y   G+   
Sbjct: 1088 CECFCSAVASYAQECTKEGACV-FWRTPD--LCPIFCDYYNPPHECEWH--YEPCGNRSF 1142

Query: 315  DTCSHLE-VSSLCEEHRMDGCF--CPEGA---QADLPKTVVLLADK 354
            +TC  +  + S      ++GC+  CP+     + DL K V   ADK
Sbjct: 1143 ETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVT--ADK 1186



 Score = 92.4 bits (228), Expect = 5e-18
 Identities = 100/401 (24%), Positives = 154/401 (38%), Gaps = 46/401 (11%)

Query: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000
            C+ WG+ HY TFDG  + + G C Y    +   S   F V++                L+
Sbjct: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILL 96

Query: 2001 VRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSY 2060
               +  + +  T H+        +N   V+ P+   GL + +S   Y       G+ + +
Sbjct: 97   TIKD--DTIYLTRHL------AVLNGAVVSTPHYSPGLLIEKSDA-YTKVYSRAGLTLMW 147

Query: 2061 NGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPH 2120
            N     +     +F N+T G CG      S    L  G + S  E    Q  +N P    
Sbjct: 148  NREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQ-KINQP---- 202

Query: 2121 CPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFD 2180
                    + P   V     +    +C      +L+    FA C  LVP + Y  AC  D
Sbjct: 203  ----DVVCEDPEEEVAPASCSEHRAECE-----RLLTAEAFADCQDLVPLEPYLRACQQD 253

Query: 2181 SCFMP-GSSLECASLQAYAALCAQQ-NICLDWRNHTHGACLVECPSHREYQACGPAEEPT 2238
             C  P G +  C+++  ++  C+       +WR  T   C   CP +  Y   G     T
Sbjct: 254  RCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTAT--LCPKTCPGNLVYLESGSPCMDT 311

Query: 2239 CK----SSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT----CGCVGPDNVPREFGEH 2290
            C     SS  +++    ++GCFCPEGT+    G   CV      C   G    P   G+ 
Sbjct: 312  CSHLEVSSLCEEHR---MDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTP---GQE 365

Query: 2291 FEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLAT 2331
               DC+ CVC  G    +C+   C   P T  +E G+++ T
Sbjct: 366  ITNDCEQCVCNAG--RWVCKDLPC---PGTCALEGGSHITT 401



 Score = 88.2 bits (217), Expect = 1e-16
 Identities = 105/469 (22%), Positives = 171/469 (36%), Gaps = 53/469 (11%)

Query: 331  MDGCFCPEGAQADLPKTVVLLADKK----KNVVVFKSDGSVLLNELQVNLPHVTASFSVF 386
            +D   C    +   P+T+++  + +    K V +      V +N   V LP+      V+
Sbjct: 4522 IDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVY 4581

Query: 387  RPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQ-VQGLCGNFNGLEGDDFKTASG 445
            +    +++    +GV +       +   V L     G   +G CG       DD    SG
Sbjct: 4582 QSGINYVVDIPELGVLVSYN---GLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSG 4638

Query: 446  LVEATGAGFANTW----KAQSSCHDKLDWLDDPCSLNIESANYAEH-------WCSLLKK 494
             + +     A+ W     ++  C         P            H        C L+K 
Sbjct: 4639 EIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIK- 4697

Query: 495  TETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHV 554
             ++ F +CH+ V P  YY  C +D+C         CA+L +YA  C  + + L  WR H 
Sbjct: 4698 -DSLFAQCHALVPPQHYYDACVFDSC-FMPGSSLECASLQAYAALCAQQNICL-DWRNHT 4754

Query: 555  CNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCV 614
                +  CP+ + +       + TC+S S   ++ +     V+GC CP+ T     G  V
Sbjct: 4755 HGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV----LVEGCFCPEGTMNYAPGFDV 4810

Query: 615  PLAKCSCY-HRGLYLEAGDVVVRQEERCVCRDG--RLHCRQIRLIGQSCTAPKIHMDCSN 671
             +  C C     +  E G+      + CVC +G   + C+  R     C+   +     +
Sbjct: 4811 CVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKR-----CSQKPVTHCVED 4865

Query: 672  LTALATSKPRALSCQTLAAGYYHTECV--SGCVCPDGLMDDGR---GGCV----VEKECP 722
             T LAT    A +C  +     +T        VCP G     +   G C      E +  
Sbjct: 4866 GTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGV 4925

Query: 723  CVHNNDLYSSGAKI-KVDCNTCTCK--------RGRWVCTQAVCHGTCS 762
            CVH N  Y  G+ +    C  C C              CT   C+ +CS
Sbjct: 4926 CVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 4974



 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 79/335 (23%), Positives = 124/335 (37%), Gaps = 35/335 (10%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILL 96
            C+ WG+ HY TFDG  + + G C Y    +   S   F V++                L+
Sbjct: 4481 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 4540

Query: 97   TIKD--DTIYLTRHL------AVLNGAVVSTPHYSPGLLIEKSDA-YTKVYSRAGLTLMW 147
               +  + +  T H+        +N   V+ P+   GL + +S   Y       G+ + +
Sbjct: 4541 VRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSY 4600

Query: 148  NREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQ-KINQP---- 202
            N     +     +F N+T G CG      S    L  G + S  E    Q  +N P    
Sbjct: 4601 NGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPH 4660

Query: 203  ----DVVCEDPEEEVAPASCSEHRAECE-----RLLTAEAFADCQDLVPLEPYLRACQQD 253
                    + P   V     +    +C      +L+    FA C  LVP + Y  AC  D
Sbjct: 4661 CPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFD 4720

Query: 254  RCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPC 313
             C  P G +  C+++  ++  C+       +WR  T          CP +  Y   G   
Sbjct: 4721 SCFMP-GSSLECASLQAYAALCAQQ-NICLDWRNHTHG---ACLVECPSHREYQACGPAE 4775

Query: 314  MDTCSHLEVSSLCEEHR---MDGCFCPEGAQADLP 345
              TC     SS  +++    ++GCFCPEG     P
Sbjct: 4776 EPTCK----SSSSQQNNTVLVEGCFCPEGTMNYAP 4806



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 51/176 (28%), Positives = 74/176 (42%), Gaps = 34/176 (19%)

Query: 1734 TTTSPPGTPTRGTTTGSSSAPTPSTVQTTTT------SAWTPTPTPLS------------ 1775
            TT + P TPT  TTT +++ PT STV +TT       S W     P S            
Sbjct: 1269 TTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDG 1328

Query: 1776 ---TPSIIRTTGLRPYPSSV-----LICCVLNDTYYAPGEEVY-NGTYGDTCYFVNCSLS 1826
                P  I    ++    S+      + C ++  +    E+ + NG +G  CY     ++
Sbjct: 1329 VCGAPEDIECRSVKDPHLSLEQLGQKVQCDVSVGFICKNEDQFGNGPFG-LCYDYKIRVN 1387

Query: 1827 CTLEFYNWSCPSTPSP---TPTPSKSTPTPSKPSSTPSKP-TPGTKPPECPDFDPP 1878
            C        C +TPSP   TP+P  ++ T   P++TPS P T  T PP      PP
Sbjct: 1388 CCWPMDK--CITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPP 1441


>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
          Length = 2013

 Score = 1271 bits (3288), Expect = 0.0
 Identities = 768/1993 (38%), Positives = 1015/1993 (50%), Gaps = 286/1993 (14%)

Query: 28   RTRNHGHN--VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQA 85
            R  N  HN  VCSTWG+FHYKTFDGDVFRFPGLC+Y F+  C  +Y++F + L+R   Q 
Sbjct: 70   RASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRS--QE 127

Query: 86   EAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTL 145
             A   +  +L+ +    I LT+   ++NG  V  P    G+LI++S +YTKV +R GL L
Sbjct: 128  SAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVL 187

Query: 146  MWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVV 205
            MWN +D+L+LELDTK+ N TCGLCGD+NG+   SE LS     +P+EFGN+QK++ P   
Sbjct: 188  MWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDDPTEQ 247

Query: 206  CEDPEEEVAPASCSEHRAECERLLTAEAFADC--------------QDLV---------- 241
            C+DP  E  P +CS     CE LL  + F+ C              QDL           
Sbjct: 248  CQDPVPE-PPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSC 306

Query: 242  ---PLEPYLRAC------------------------QQDRCRCPGGDTCVCSTVAEFSRQ 274
                L  Y R C                        Q   CR P  DTC   +  E SR 
Sbjct: 307  VCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTC---SNQEHSRA 363

Query: 275  CSH---AG------------GRPGNWRTAT-------SAVSPGASK-------TCPGNLV 305
            C     AG            G+ G    +        +A +PGA+        TC G   
Sbjct: 364  CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRW 423

Query: 306  YLESGSPCMDTCSHLEVSSLC----EEHRMDG-CF------CPEGAQADLP--------- 345
              +   PC  TCS L  +       +++ + G C       C   A   L          
Sbjct: 424  SCQE-VPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD 482

Query: 346  -----KTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIG 400
                 K+V L  D  + VVV K+ G V LN++   LP   A+ ++FRPS++ I+   ++G
Sbjct: 483  SETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLG 542

Query: 401  VRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKA 460
            ++L +QL P MQLF+ L    +GQ  GLCGNFN ++ DDF+T SG+VEAT A F NT+K 
Sbjct: 543  LQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT 602

Query: 461  QSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTC 520
            Q++C +  +  +DPCSL++E+  YA+HWCS L   + PFGRCH+AV P  YY  C +DTC
Sbjct: 603  QAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTC 662

Query: 521  NCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCR 580
            NC+ +EDCLCAALSSY  AC AKGV L GWR+ VC K + +CP S  + Y+++TCQ TCR
Sbjct: 663  NCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCR 722

Query: 581  SLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEER 640
            SLSE D  C  GF PVDGC CP  TFLD+ G+CV  + C CYHRG  +  G+ V      
Sbjct: 723  SLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAI 782

Query: 641  CVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSG 700
            C C  G+L C   +     C AP +  DC N T   T      SC TL    Y  +CV G
Sbjct: 783  CTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPG 842

Query: 701  CVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGT 760
            CVCPDGL+ DG GGC+  ++CPCVHN   Y +G  I+V CNTCTC    W CT   C  T
Sbjct: 843  CVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLAT 902

Query: 761  CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYC-GQNSSLGSFSIITENVPCGTTGVTCSK 819
            C++YG GHY+TFDG+ Y F+G C Y  VQ++C G++S+  SF ++TENVPCGTTG TCSK
Sbjct: 903  CAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSK 962

Query: 820  AIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFI 879
            AIKIF+G  ELKL      VI  DE   V YT R++G YLVV++  G++++WDK+T++FI
Sbjct: 963  AIKIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFI 1022

Query: 880  KLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCS 939
             L+P +KG VCGLCGNFD  + NDF TR   VV   L+FGNSWK +P+CPD     +PC+
Sbjct: 1023 NLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKDPCT 1082

Query: 940  LNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASY 999
             NP R+SWA+KQCSIL    F+ CH+ V+P  +YEACV+D+C+CD+GGDCECFC+AVA+Y
Sbjct: 1083 ANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAY 1142

Query: 1000 AQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVS 1059
            AQ C + G CV WRTP +CP+FCDYYNP  +CEWHY+PCG     TCR   G      V 
Sbjct: 1143 AQACHEVGLCVSWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRG-DCLRDVW 1201

Query: 1060 YLEGCYPRCPKDRPIYEEDLKKCVTADKC-----GCYVEDTHYPPGASVPTEETCKSCVC 1114
             LEGCYP+CP + PI++ED  +CV           C+V    Y PGA VP+++ C+SC+C
Sbjct: 1202 GLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLC 1261

Query: 1115 T--------NSSQVVC-----RPEEGKILNQTQDG-AFCYWEICGPNGTVEKHFNICSIT 1160
            T         +   VC     R   G ++  T DG   C    CG NGT+E+    CS T
Sbjct: 1262 TERGVECTYKAEACVCTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPT 1321

Query: 1161 TRPSTLTTFTTITLPTT-----------------------PTTFTTTTTTTTPTSSTVLS 1197
            T P   TTF+  T P                         PTT  T+  T  PT+S  L 
Sbjct: 1322 T-PVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASL- 1379

Query: 1198 TTPKLC---CLWSDWINEDHPSSGSDDGDRETFDG-------VCGAPEDIECRSVKDPHL 1247
              P +C   CLWS W++   P  G+D GD +T +        VC +P  +ECR+   P +
Sbjct: 1380 --PPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGV 1437

Query: 1248 SLEQLGQKVQLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTT 1307
             L  LGQ+VQ  C   VGL C+N +Q  G       C NY+I VQCC     P   +T++
Sbjct: 1438 PLRALGQRVQ--CSPDVGLTCRNREQASG------LCYNYQIRVQCC----TPLACSTSS 1485

Query: 1308 TENPTPTPITTTTTVT-------PTPTP----TSTQSTTPTPITTT----TTVTPTPTPT 1352
            +   T  P T+ TT T       P+ TP     ST  TTP P T T    T  TP+P P 
Sbjct: 1486 SPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTARTTPAPGTATSVKKTFSTPSPPPV 1545

Query: 1353 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTS 1405
               + ++   TT  T   +  PT T+  T++ +    T T       P P   G    T 
Sbjct: 1546 PATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTF 1605

Query: 1406 TPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG------TQAPTPTAITT 1456
              +     T   +P       ++   TP+             G       Q P P     
Sbjct: 1606 QNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICSHTEGLICLNKNQLP-PICYNY 1664

Query: 1457 TSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQ 1516
               +    T    +  T  P T  TT  PTP PTG QT T       +  T  PT T   
Sbjct: 1665 EIRIQCCETVNVCRDITRPPKTVATT-RPTPHPTGAQTQTTFTTHMPSASTEQPTATSRG 1723

Query: 1517 TPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTT---- 1572
             PT+T +T  T  TP    T    P  T         P+P P G    T   I  +    
Sbjct: 1724 GPTATSVTQGTHTTPV---TRNCHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKI 1780

Query: 1573 -------------------------TTVTPTPTPTG-------TQTPTTVLITTTTTMTP 1600
                                       V       G        Q P  + +     +  
Sbjct: 1781 CRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLC 1840

Query: 1601 TPTPTSTKSTTVTPITTTTTVTATPTPTG-----TQTPTMIPISTTTTVTPTPTPTTGST 1655
              TP     T+       T VTA  TP+G     TQ+ +    S TTT+      TT +T
Sbjct: 1841 CETPRGCPVTS-------TPVTAPSTPSGRAISPTQSTSSWQKSRTTTLV-----TTSTT 1888

Query: 1656 GPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPST 1715
              P  ++T      TTS P   +++  T+R+TS+    +T+     P  +  TST     
Sbjct: 1889 STPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTI---- 1944

Query: 1716 PTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTV---QTTTTSAWTPTPT 1772
             +APTT+    T +P  STT++P  + T   TT ++SAPT ST    QT+TTSA T + T
Sbjct: 1945 -SAPTTSI---TSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTT 2000

Query: 1773 --PLSTPSIIRTT 1783
              P +TPS + TT
Sbjct: 2001 SGPGTTPSPVPTT 2013



 Score =  127 bits (319), Expect = 1e-28
 Identities = 130/523 (24%), Positives = 202/523 (38%), Gaps = 63/523 (12%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C    C   C+  G  H+ TFDG  Y+  G+C+YVL +    S   F V  +   C   D
Sbjct: 425  CQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSA--FTVLAELRRCGLTD 482

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
              +C +++ +  +     ++TV ++    +V +N+    LP     + +++    +++  
Sbjct: 483  SETCLKSVTLSLDG----VQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQ 538

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQ-CGTCTNTTS---DDCILPSGEIVSNCEAA 2107
              LG+ ++   L  +++L + +     +GQ CG C N  S   DD    SG +    EA 
Sbjct: 539  TSLGLQLNLQ-LVPTMQL-FMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVV----EAT 592

Query: 2108 ADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDS--LFAQCH 2165
            A  +     ++  CP+  ++ + P        K   H        C  + D+   F +CH
Sbjct: 593  AAAFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQH-------WCSQLTDADGPFGRCH 645

Query: 2166 ALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALCAQQNICL-DWRNHTHGACLVECP 2223
            A V P  YY  C+FD+C    S    CA+L +Y   CA + + L  WR+      +  CP
Sbjct: 646  AAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCP 705

Query: 2224 SHREYQACGPAEEPTCKSSSSQQNNT----VLVEGCFCPEGTMNYAPGFDVCVKTCGCVG 2279
                Y       +PTC+S S          + V+GC CP+GT     G  V    C C  
Sbjct: 706  KSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYH 765

Query: 2280 PDN-VPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYL-ATEVNPAD 2337
              + +P   GE        C C  G    I       Q P   C     +       P D
Sbjct: 766  RGSMIPN--GESVHDSGAICTCTHGKLSCI-----GGQAPAPVCAAPMVFFDCRNATPGD 818

Query: 2338 T------CCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA 2391
            T       C+     C +  C     VCP G     +   G C     C     CVH  A
Sbjct: 819  TGAGCQKSCHTLDMTCYSPQC-VPGCVCPDGLVADGE---GGCITAEDCP----CVHNEA 870

Query: 2392 EYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434
             Y+ G  +    C  C C  +        +  CT  PC  +C+
Sbjct: 871  SYRAGQTIRVG-CNTCTCDSR--------MWRCTDDPCLATCA 904



 Score =  111 bits (278), Expect = 8e-24
 Identities = 113/414 (27%), Positives = 167/414 (40%), Gaps = 63/414 (15%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE----ISPSVDNFGVYIDNYHC 1987
            C    C   C  +GD HY+TFDG  YS+ G+C Y LV+        + D+F V  +N  C
Sbjct: 894  CTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPC 953

Query: 1988 DPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINY 2047
                  +C + + +     E  +K  H    +V+V    ++  +PY      + Q GI  
Sbjct: 954  GTTG-TTCSKAIKIFLGGFE--LKLSH---GKVEVIGTDESQEVPY-----TIRQMGIYL 1002

Query: 2048 VVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAA 2107
            VVD     VL+     S  + L    F     G CG   +   +D    S  +V +    
Sbjct: 1003 VVDTDIGLVLLWDKKTSIFINLS-PEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEF 1061

Query: 2108 ADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHAL 2167
             + W ++    P CP  +   K P           P +       C ++    FA CHA 
Sbjct: 1062 GNSWKLS----PSCP-DALAPKDPCT-------ANPFRKSWAQKQCSILHGPTFAACHAH 1109

Query: 2168 VPPQHYYDACVFDSCFM-PGSSLE--CASLQAYAALCAQQNICLDWRNHTHGACLVECPS 2224
            V P  YY+ACV D+C    G   E  C ++ AYA  C +  +C+ WR  T   C + C  
Sbjct: 1110 VEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVSWR--TPSICPLFCDY 1167

Query: 2225 HR-------EYQACGPAEEPTCKSSSSQQNNTVL-VEGCF--CPEGTMNYAPGFD----V 2270
            +         YQ CG     TC++        V  +EGC+  CP      AP FD     
Sbjct: 1168 YNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPP----EAPIFDEDKMQ 1223

Query: 2271 CVKTCGCVGPDNVPR--EFGEHF--------EFDCKNCVCLEGGSGIICQPKRC 2314
            CV TC    P   PR    G+ +        + +C++C+C E G     + + C
Sbjct: 1224 CVATCPT--PPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEAC 1275



 Score =  108 bits (271), Expect = 5e-23
 Identities = 110/402 (27%), Positives = 165/402 (41%), Gaps = 49/402 (12%)

Query: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000
            C+ WG  HY TFDG  + + G C YV  E    + ++F + +       + + + P    
Sbjct: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRR-----SQESAAPTLSR 135

Query: 2001 VRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSY 2060
            V  +   V+I+       +  V VN   V LP+ + G+ + QS  +Y      LG+++ +
Sbjct: 136  VLMKVDGVVIQLT-----KGSVLVNGHPVLLPFSQSGVLIQQSS-SYTKVEARLGLVLMW 189

Query: 2061 NGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPH 2120
            N     +     ++ N T G CG          +L     ++  E    Q + +DP    
Sbjct: 190  NHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKM-DDP---- 244

Query: 2121 CPHSSSTTKRPAVTVPGGGKTTPHKDC-TPSPLCQ-LIKDSLFAQCHALVPPQHYYDACV 2178
                   T++    VP      P ++C T   +C+ L+   LF+ C ALV    Y +AC 
Sbjct: 245  -------TEQCQDPVP-----EPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACR 292

Query: 2179 FDSCFMPGSSL---ECASLQAYAALCAQQN-ICLDWRNHTHGACLVECPSHREYQACGPA 2234
             D CF   + L    C +L  Y+  C     +  DWR      C  +CP++ +Y  C   
Sbjct: 293  QDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDF--CPQKCPNNMQYHECRSP 350

Query: 2235 EEPTCKSSS-SQQNNTVLVEGCFCPEGTMNYAPGFDVC--VKTCGCV--GPDNVPREFGE 2289
               TC +   S+      V GCFCPEGT+    G   C  V  C CV  G    P   G 
Sbjct: 351  CADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP---GA 407

Query: 2290 HFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLAT 2331
             +  DC NC C   G    CQ   C   P T  V  G + +T
Sbjct: 408  TYSTDCTNCTC--SGGRWSCQEVPC---PGTCSVLGGAHFST 444



 Score = 99.4 bits (246), Expect = 4e-20
 Identities = 144/574 (25%), Positives = 200/574 (34%), Gaps = 103/574 (17%)

Query: 1360 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPT 1419
            TP+  +T+ +P  T     TP TT  TT T  +      G+  P+STP T + +   T  
Sbjct: 1477 TPLACSTSSSPAQT-----TPPTTSKTTETRAS------GSSAPSSTPGTVSLSTART-- 1523

Query: 1420 PTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITT 1479
               T  P T      T  TP+P P    + +  + TT  T   +  PT T+  T++ +  
Sbjct: 1524 ---TPAPGTATSVKKTFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQE 1580

Query: 1480 TTTVT-------PTPTPTGTQTPTPTAITT---TTTVTPTPTPTGTQTPTSTPITTTTTV 1529
              T T       P P   G    T   +     T   +P       ++  +TP+      
Sbjct: 1581 LCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQD 1640

Query: 1530 TPTPTPTG------TQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1583
                   G       Q P P   +    +    T    +  T  P T  TT  PTP PTG
Sbjct: 1641 VICSHTEGLICLNKNQLP-PICYNYEIRIQCCETVNVCRDITRPPKTVATT-RPTPHPTG 1698

Query: 1584 TQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTT 1643
             QT TT      +  T  PT TS    T T +T  T  T         T    P  T T 
Sbjct: 1699 AQTQTTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPV-------TRNCHPRCTWTK 1751

Query: 1644 VTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLT----------- 1692
                  P+ G  G    T    I         PE  T    R+ S P             
Sbjct: 1752 WFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQC 1811

Query: 1693 -----------------------ESTTLLSTLPPAIEMTST--APPSTPT----APTTTS 1723
                                   E   L    P    +TST    PSTP+    +PT ++
Sbjct: 1812 SREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQST 1871

Query: 1724 GG-----HTLSPPPSTTTSPPGTPTRGTTTGSSSAPT-----PSTVQTTTTSAWTPTPTP 1773
                    T     STT++P  + T   TT ++SAPT       T +TT+ S  + T  P
Sbjct: 1872 SSWQKSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGP 1931

Query: 1774 LSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYN 1833
             +TPS + TT     P++ +       T  AP           T    +   + T     
Sbjct: 1932 GNTPSPVPTTSTISAPTTSITSAPTTSTTSAP-----------TSSTTSAPTTSTTSAPT 1980

Query: 1834 WSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGT 1867
             S  S+P  + T + +T T S P +TPS P P T
Sbjct: 1981 SSTTSSPQTSTTSAPTTSTTSGPGTTPS-PVPTT 2013



 Score = 40.8 bits (94), Expect = 0.018
 Identities = 37/124 (29%), Positives = 47/124 (37%), Gaps = 19/124 (15%)

Query: 2311 PKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMV 2370
            P  C QK    C  +  Y       ADTC N    +     C      CP G  +     
Sbjct: 331  PDFCPQK----CPNNMQYHECRSPCADTCSNQEHSRACEDHCVAG-CFCPEGTVLDDIGQ 385

Query: 2371 PGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCN 2430
             G C P     SK  CV+  A Y PG+  YS+ C +C C+            +C  VPC 
Sbjct: 386  TG-CVPV----SKCACVYNGAAYAPGA-TYSTDCTNCTCSG--------GRWSCQEVPCP 431

Query: 2431 TSCS 2434
             +CS
Sbjct: 432  GTCS 435



 Score = 40.4 bits (93), Expect = 0.023
 Identities = 56/197 (28%), Positives = 72/197 (36%), Gaps = 39/197 (19%)

Query: 1708 TSTAPPST---PTAPTTTSGGHTLSPPPSTT-TSPPGT--PTRGTTTGSSSAPT------ 1755
            T+  PP+T    T P   S  HT S  PS+  T PP +  PT   T+  +  PT      
Sbjct: 1321 TTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLP 1380

Query: 1756 PSTVQTTTTSAWTPTPTP--------LSTPSIIRTTGLRPYPSSVLICCVLNDTYYAP-- 1805
            P   +    S W     P          T   +R  G R   S   + C   D    P  
Sbjct: 1381 PVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLR 1440

Query: 1806 --GEEVY-NGTYGDTC------------YFVNCSLSCTLEFYNWSCPSTPSPTPTPSKST 1850
              G+ V  +   G TC            Y +       L     S P+  +P PT SK+T
Sbjct: 1441 ALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSSSPAQTTP-PTTSKTT 1499

Query: 1851 PTPSKPSSTPSKPTPGT 1867
             T +  SS PS  TPGT
Sbjct: 1500 ETRASGSSAPSS-TPGT 1515



 Score = 33.1 bits (74), Expect = 3.7
 Identities = 30/92 (32%), Positives = 38/92 (41%), Gaps = 18/92 (19%)

Query: 1796 CVLNDTYYAPGEEVYNGTYGDT-CYFVNCSLSCTLEFYNWSCPSTPSPTPTP-SKSTP-- 1851
            C  N   + PG+ +Y+ T G   C    C  + T+E   + C  T    PT  S STP  
Sbjct: 1277 CTYNGQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPL 1336

Query: 1852 ------TPSK-PSSTPSKP-------TPGTKP 1869
                  TPS  PSS  + P       T GT P
Sbjct: 1337 VVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSP 1368



 Score = 32.3 bits (72), Expect = 6.4
 Identities = 53/258 (20%), Positives = 79/258 (30%), Gaps = 26/258 (10%)

Query: 2317 KPVTHCVEDGTYLATEVNPADTCCNITV--CKCNTSLCKEKPSVCPLG--FEVKSKMVPG 2372
            KP+T C +  TY         TC +++     C+         +CP G   +   K V  
Sbjct: 699  KPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQA 758

Query: 2373 RCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTS 2432
              CP         C H  +    G  V+ S    C CT    +  L  +      P   +
Sbjct: 759  SNCP---------CYHRGSMIPNGESVHDSGAI-CTCT----HGKLSCIGGQAPAPVCAA 804

Query: 2433 CSPGFELMEA-PGE----CCKKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNC-TFFSCV 2486
                F+   A PG+    C K C         P      + P    +D +  C T   C 
Sbjct: 805  PMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCP 864

Query: 2487 KIHNQLISSVSNITCPNFDASICIPGSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSY 2546
             +HN+             +   C         + C  TC    +      T    +    
Sbjct: 865  CVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHY--LTFDGQSYSFN 922

Query: 2547 AGCTKTVLMNHCSGSCGT 2564
              C  T++ NHC G   T
Sbjct: 923  GDCEYTLVQNHCGGKDST 940


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 1152 bits (2979), Expect = 0.0
 Identities = 621/1466 (42%), Positives = 808/1466 (55%), Gaps = 173/1466 (11%)

Query: 32   HGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGV 91
            H   VCSTWG+FHYKTFDGDVFRFPGLC+Y F+  CR +Y++F V L+RG     +   V
Sbjct: 72   HNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRG--LVGSRPVV 129

Query: 92   ESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNRED 151
              +++  +   +  +    ++NG     P+   GLL+E+S  Y KV  R  LT +WN ED
Sbjct: 130  TRVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGED 189

Query: 152  ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCEDPEE 211
            + +LELD K+ N TCGLCGD+NGL +++EF +     +PL+FGN+QK++ P   C DP  
Sbjct: 190  SALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLP 249

Query: 212  EVAPASCSE-----HR-------AECERLLTAEAF--ADCQDLV--PLEP------YLRA 249
              A  +C++     HR       AEC  L+ + A+  A  QDL   P  P      Y R 
Sbjct: 250  LPA-GNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCATFVEYSRQ 308

Query: 250  C------------------------QQDRCRCPGGDTCV--------------------- 264
            C                        Q   C  P  DTC                      
Sbjct: 309  CAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPG 368

Query: 265  --CSTVAEFSRQ---------CSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPC 313
              C+ + + +           C+H GGR   +   TS  +  +S TC G L   +   PC
Sbjct: 369  RSCTVLDDITHSGCLPLGQCPCTH-GGR--TYSPGTSFNTTCSSCTCSGGLWQCQD-LPC 424

Query: 314  MDTCS-----------------HLEVSSLCEEHRMDGCF--------CPEGAQADLPKTV 348
              TCS                 H + S +  +   D  F        C      +  K V
Sbjct: 425  PGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENCLKAV 484

Query: 349  VLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLA 408
             L  D     +  ++DG V LN +   LP   A+ ++F PSS+ I+V   +G++L VQL 
Sbjct: 485  TLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLV 544

Query: 409  PVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKL 468
            P+MQ+FV LD A QGQ+ GLCGNFN  + DDF   SG+VEATGA FANTWKAQ++C +  
Sbjct: 545  PLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANAR 604

Query: 469  DWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDC 528
            +  +DPCSL++E+ NYA HWCS L    + F RCHS ++P  ++  C +DTCNC+ +EDC
Sbjct: 605  NSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDC 664

Query: 529  LCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSH 588
            LCAALSSY  AC AKGV L  WR+ VC K + +CP SQ + Y +  CQ TCR LSEAD  
Sbjct: 665  LCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVT 724

Query: 589  CLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRL 648
            C   F PVDGC CP  TFL++ G CVP  +C CY  G  L  G+VV  +   C C  G+L
Sbjct: 725  CSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKL 784

Query: 649  HCRQIRL-IGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGL 707
             C    L     C AP +++DCSN +A         SC TL  G + T CVSGCVCP GL
Sbjct: 785  SCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGL 844

Query: 708  MDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSG 767
            + DG GGC+ E++CPCVHN   Y  G  I+VDCNTCTC+  RW C+  +C GTC  YG G
Sbjct: 845  VSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDG 904

Query: 768  HYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGR 827
            H+ITFDG  Y F+G C Y+  QDYCG N++ G+F I+TEN+PCGTTG TCSKAIK+F+  
Sbjct: 905  HFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVES 964

Query: 828  TELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKG 887
             EL L++     + R  G    Y  R +G +LV+E+  G+ V WD++T+VFI+L   YKG
Sbjct: 965  YELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKG 1023

Query: 888  TVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSW 947
             VCGLCGNFD  + NDF TR   VV   L+FGNSWK +P+CPD     +PC+ NP R+SW
Sbjct: 1024 RVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSW 1083

Query: 948  AEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEG 1007
            A+KQCSIL    F+ C S+VD   +YEACV+D+C+CD+GGDCECFC+AVA+YAQ C   G
Sbjct: 1084 AQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAG 1143

Query: 1008 ACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPR 1067
             CV WRTPD CP+FCD+YNP   CEWHY+PCG    +TCR  +G H  + +  LEGCYP+
Sbjct: 1144 LCVSWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSG-HCLVDLPGLEGCYPK 1202

Query: 1068 CPKDRPIYEEDLKKCVTADKCGCYVED-THYPPGASVPTEETCKSCVCTNS--------S 1118
            CP  +P + ED  KCV   +CGCY +D  +Y  GA VPT E C+SC CT S         
Sbjct: 1203 CPPSQPFFNEDQMKCVA--QCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLE 1260

Query: 1119 QVVCRPE------EGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTRPSTLTTFTTI 1172
               C  E      +  I N T     C   ICG NGT+ +    C  T            
Sbjct: 1261 ACTCTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPGTP----------- 1309

Query: 1173 TLPTTPTTFTTTTT--TTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDG- 1229
               TTP TFTT     +TT  +  V +   +  C WS W N   P  G   GD ETF+  
Sbjct: 1310 --ATTPFTFTTAWVPHSTTSPALPVSTVCVREVCRWSSWYNGHRPEPGLGGGDFETFENL 1367

Query: 1230 ------VCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQKPGGVIPMAF 1283
                  VC    DIECR+ + P + LE+LGQ+V   CD   GL+C N  Q P        
Sbjct: 1368 RQRGYQVCPVLADIECRAAQLPDMPLEELGQQVD--CDRMRGLMCANSQQSP------PL 1419

Query: 1284 CLNYEINVQCCECV---------TQPTTMTTTTTENPTPTPITTT----TTVTPTPTPTS 1330
            C +YE+ V CCE V         T P    + +TE   PTP  TT    TT+  TP+  S
Sbjct: 1420 CHDYELRVLCCEYVPCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRS 1479

Query: 1331 TQSTTPTPITTTTTVTPTPTPTGTQT 1356
            T + T    +++  VT TP+  GT T
Sbjct: 1480 TAALTSQTGSSSGPVTVTPSAPGTTT 1505



 Score =  825 bits (2132), Expect = 0.0
 Identities = 589/1700 (34%), Positives = 815/1700 (47%), Gaps = 291/1700 (17%)

Query: 1160 TTRPSTLTTFTTITLPTTPT-TFTTTTTTTTPTSS---TVLSTTPKLCCLWSDWINEDHP 1215
            TT P   T  +  T   TP+ T T+T   ++PTS+   TV++T  +  C WS+W++  +P
Sbjct: 4087 TTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYP 4146

Query: 1216 SSGSDDGDRETFDG-------VCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLIC 1268
              G   GD +T+         VC  P  +ECR+   P + L +LGQ V+  C +  GL+C
Sbjct: 4147 MPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVE--CSLDFGLVC 4204

Query: 1269 KNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTP--------ITTTT 1320
            +N +Q    V     C NYEI V CC     P+T  T++T  P+ TP        +TTT 
Sbjct: 4205 RNREQ----VGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTA 4260

Query: 1321 TVTP----TPTPTSTQSTTPTP-ITTTTTVTPTPTPT------GTQTPTTTPI------- 1362
            T T     T TP+ST  T P P + T+   TPT T +        +T TT P+       
Sbjct: 4261 TTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATK 4320

Query: 1363 TTTTTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTP-------------------T 1398
            +T T+VTP P+ T   T      TTTP+ T +T+ P+ TP                   +
Sbjct: 4321 STATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATS 4380

Query: 1399 GTQTPTSTPITT----------TTTVTPTPTPTGTQTPTTT----PITTTTTVTPTPTPT 1444
             T TP+STP TT          TTT    PT T + TP TT     +TTT T T +   T
Sbjct: 4381 STSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGST 4440

Query: 1445 GTQAPTP------TAITTTSTVT----PTPTPTGTQTPTTTPITTTTTVTPTPTPT---- 1490
             T + TP      T  +TT+TVT     T T + TQ    TP  +TT  TPT T +    
Sbjct: 4441 ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATP 4500

Query: 1491 ----GTQTP---------TPTAI-----------TTTTTVTPTPTPTGTQ---TPTSTPI 1523
                GT T          TPTA            TT T ++ T TPT T    TP+STP 
Sbjct: 4501 SSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE 4560

Query: 1524 T--TTTTVTPTPTPTGTQ----TPTPTPISTTTTVTPTPTPTG-TQTPTTTP-------- 1568
            T  T+T +T T T TG      TP+ TP +  TT  PT T TG T TP+++P        
Sbjct: 4561 TVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPV 4620

Query: 1569 ----ITTTTTVTPTPTPTGTQTPTTV--------LITTTTTMTPT---PTPTSTKSTTVT 1613
                 TT TT TPT T   T TP+++        ++TTTTT   T    TP+S+  T+ T
Sbjct: 4621 WISTTTTPTTTTPT-TSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGT 4679

Query: 1614 P---ITTTTTVTATPTPTG-TQTPTMIPI-----STTTTVTPTPTPTTGSTGP------P 1658
            P    TT TT+TAT + T  + TP   PI     ST TT   T +  T S+ P      P
Sbjct: 4680 PPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLP 4739

Query: 1659 THTSTAPIAELTTSNP------------PPESSTPQTSRST----SSPLT--ESTTLLST 1700
              TSTA  +  T+  P            P +++TP ++ ST    S+P T   ST L +T
Sbjct: 4740 VLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTT 4799

Query: 1701 LPPAIEMTSTAPPS------------TPTAPTTTSGGH--TLSPPPSTT--TSPPGT--- 1741
                    STA PS            T TA TT + G   TLS  P TT   + P T   
Sbjct: 4800 ATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIAT 4859

Query: 1742 ---PTRGTTTGS-----------------------SSAPTPSTVQTTTTSAWTPTPTP-- 1773
               PT  T T S                       S+ P+ STV TT T A  P+  P  
Sbjct: 4860 VMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTF 4919

Query: 1774 -LSTPSIIRTTGLRP--YPS---SVLICCVLNDTYYAPGEEVYNGTYGDTCYF-VNCSLS 1826
             +ST S    T LRP  +PS   S    C     +++PGE +YN T    C+F   C+  
Sbjct: 4920 SVSTVSSSVLTTLRPTGFPSSHFSTPCFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQH 4979

Query: 1827 CTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWW 1886
            C ++ +  +CP++P P  +   S+P+P+               P C +  P RQ NETW 
Sbjct: 4980 CDIDRFQGACPTSPPPVSSAPLSSPSPA---------------PGCDNAIPLRQVNETWT 5024

Query: 1887 LCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDP-DGCCWHWECDCYCTGWG 1945
            L +C +A C  +N   +V ++ +P    TC N   P++V DP   C +H+EC+C C+ WG
Sbjct: 5025 LENCTVARCVGDN--RVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECICSMWG 5082

Query: 1946 DPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVS---CPRTLIVR 2002
              HY TFDG  Y+++GNCTYVL+ EI     N  +Y+DN++C  +   +   CPR L + 
Sbjct: 5083 GSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAARCPRALSIH 5142

Query: 2003 HETQEVLIKTVHMMPMQVQ--VQVNRQAVALPYKKYGLEVYQSGINYV-VDIPELGVLVS 2059
            +++ ++++ TV M+  + +  +  ++  V+  + K G+ V   G   + VDIP LGV V+
Sbjct: 5143 YKSMDIVL-TVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVT 5201

Query: 2060 YNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKP 2119
            +NG  F  RLPY  F NNT+GQCGTCTN   DDC+   G   ++C+  A  WLV D  K 
Sbjct: 5202 FNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKD 5261

Query: 2120 HC--PHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDAC 2177
             C  P  +  T  PA  V      TP   C P PLC L+   +FA+CH LVPP  +++AC
Sbjct: 5262 GCWAPTGTPPTASPAAPVSSTPTPTP---CPPQPLCDLMLSQVFAECHNLVPPGPFFNAC 5318

Query: 2178 VFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEP 2237
            + D C      + C SL+AYA LC  + +C DWR  T G C + CP  + Y+ CGP +  
Sbjct: 5319 ISDHC-RGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPA 5377

Query: 2238 TCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKN 2297
            TC S +       + EGCFCPE  + +     +CV+ C CVGPD  P+  GE +  +C++
Sbjct: 5378 TCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNCQS 5437

Query: 2298 CVCLEGGSGIICQPKRC-SQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKP 2356
            CVC EG   + C+P  C +Q     C   G    T     + CC  TVC CNT+ C +  
Sbjct: 5438 CVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSL 5497

Query: 2357 SVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSS-KCQDCVCTDKVDN 2415
             VCP G E       G CCP + C  + +C +    Y  G+    +  C  C C   +  
Sbjct: 5498 PVCPPGQESICTQEEGDCCPTFRCRPQ-LCSYNGTFYGVGATFPGALPCHMCTC---LSG 5553

Query: 2416 NTLLNVIACTHVPC-NTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQHVILKPGDFKS 2474
            +T    + C    C NT+C  GFE     G+CC +C QT C+   PD Q V L    + +
Sbjct: 5554 DTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACL--TPDGQPVQLNE-TWVN 5610

Query: 2475 DPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIPGSITFMPNGCCKTCTPRNETRVP 2534
               +NCT + C       + +    +CP  D S C  GS+     GCC +C   +     
Sbjct: 5611 SHVDNCTVYLCEAEGGVHLLTPQPASCP--DVSSC-RGSL--RKTGCCYSCEEDS----- 5660

Query: 2535 CSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEEKTSQREVVL 2594
            C     TT + + GC   V +  C GSC     YSA+AQA+ H C+CC+E +  +  V L
Sbjct: 5661 CQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHEETVPL 5720

Query: 2595 SCPNGGSLTHTYTHIESCQC 2614
             CPNG ++ HTYTH++ C C
Sbjct: 5721 HCPNGSAILHTYTHVDECGC 5740



 Score =  305 bits (782), Expect = 3e-82
 Identities = 262/758 (34%), Positives = 350/758 (46%), Gaps = 142/758 (18%)

Query: 1160 TTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLC---CLWSDWINEDHPS 1216
            TT   T  T  T    T   T T+T   ++PTS+ + +     C   C WS+W++  +P 
Sbjct: 2831 TTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPM 2890

Query: 1217 SGSDDGDRETFDG-------VCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICK 1269
             G   GD +T+         VC  P  +ECR+   P + L +LGQ V+  C +  GL+C+
Sbjct: 2891 PGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVE--CSLDFGLVCR 2948

Query: 1270 NEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTP------------IT 1317
            N +Q    V     C NYEI V CC     P+T  T++T  P+ TP             T
Sbjct: 2949 NREQ----VGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAAT 3004

Query: 1318 TTTTVTPTPTPTSTQSTTPTP-ITTTTTVTPTPTPT------GTQTPTTTPI-------T 1363
            TT T   T  P+ST  T P P + T+T  TPT T +        +T TT P+       +
Sbjct: 3005 TTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKS 3064

Query: 1364 TTTTVTPTPT----PTGT-QTPTTTPITTTTTVTPTPTPTGTQTPT--STPITTTTTVTP 1416
            T T+ TP P+     TGT    TTTP+ T +T+ P+ TP  T T T  +T  TTT   + 
Sbjct: 3065 TATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSS 3124

Query: 1417 TPTPTGTQ------TPTTTPITTTTTVTPTPTPTGTQA-------PTPTAITT-----TS 1458
              TP+ T       T  TT  TTT    PT TP+ T         P+ TA  T     T+
Sbjct: 3125 MSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTA 3184

Query: 1459 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTPTAITTTTTVTPTPTPTGT 1515
            T + T    GT    T+  TT T ++   TP+   GT T  P   +T TT T T     T
Sbjct: 3185 TASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSV---T 3241

Query: 1516 QTPTSTPITTTTTVTPTPTPTGTQ---TPTPTP--ISTTTTVTPTPTPT----GTQTPTT 1566
              P+S+  T  T ++ T TPT T    TP+ TP  + T+T +T T T T       TP++
Sbjct: 3242 AIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSS 3301

Query: 1567 TPITTTTTVTPTPTPTG-TQTPTT---------VLITTTTTMT---PTPTPTSTKST--T 1611
            TP T  TT  PT T TG T TP++         V I+TTTT T    T TP+S   T  T
Sbjct: 3302 TPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHT 3361

Query: 1612 VTPITTTTTVTAT---PTPTGTQTPTMIPISTTTTVT----------PTPTP-------- 1650
             T +TTTTT  AT    TP+ +   +  P S TTT T          P+ TP        
Sbjct: 3362 ATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPV 3421

Query: 1651 --TTGSTGPPTHTSTAPIAELTTSNPPPESSTPQT----SRSTSSPLTESTTLLSTLPPA 1704
              TT +T   T ++  P + L T++ PP  +T  T    S   SSP T  T   S     
Sbjct: 3422 LTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGI 3481

Query: 1705 IEMTSTAPPSTPT----APTTTSGGHTL----SPPPS--TTTSP--PGTPTRGTTTGSS- 1751
            +  T    PST T    A TT++  H+     SP PS  TT SP  PGT T G T G+S 
Sbjct: 3482 LGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSR 3541

Query: 1752 --SAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRP 1787
              +  TPS  +T+T    +PT  P++T   + TTG  P
Sbjct: 3542 TTATATPSKTRTSTLLPSSPTSAPITT---VVTTGCEP 3576



 Score =  290 bits (741), Expect = 2e-77
 Identities = 279/840 (33%), Positives = 365/840 (43%), Gaps = 135/840 (16%)

Query: 1099 PGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNICS 1158
            PG +  T  T  +   T  S    RP +   L  T            P GT         
Sbjct: 1689 PGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMAT----SRARPTGTASTASKEPL 1744

Query: 1159 ITTRPSTLTTFTTITLPTTPTTFTTTTT---TTTPTSSTVLSTTPKLCCLWSDWINEDHP 1215
             T+   TLT+  + +   T T  T TT    T T TS       PK  C W++W + D P
Sbjct: 1745 TTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPK--CEWTEWFDVDFP 1802

Query: 1216 SSGSDDGDRETFDGV-------CGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLIC 1268
            +SG   GD ETF+ +       C AP+ IECR+   P +S++Q+GQ   L C +  GL C
Sbjct: 1803 TSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQV--LTCSLETGLTC 1860

Query: 1269 KNEDQKPGGVIPMAFCLNYEINVQCCECVTQ-PTTMTTTTTENPTPTPITTTTTVTPTPT 1327
            KNEDQ   G   M  C NY + V CC+  +  P+T  T++T  P+ TP TT     PT T
Sbjct: 1861 KNEDQT--GRFNM--CFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTT 1916

Query: 1328 PTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1387
             T+T ST  T  T T+T+   P P    T  TTP  T++  TP+ +P    T T  P   
Sbjct: 1917 ATTTASTGST-ATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSP---GTATALPALR 1972

Query: 1388 TTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQ---TPTTTPIT--TTTTVTPTPT 1442
            +T  TPT T   T  P+S+  TT T ++ T TPT T    TP++TP T  T+T +T T T
Sbjct: 1973 STATTPTATSV-TPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATAT 2031

Query: 1443 PTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTPTAIT 1501
             TG          T S  TP+ TP GT   T  P TTTT  T TP+ + GT    P  I+
Sbjct: 2032 TTG---------ATGSVATPSSTP-GTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIS 2081

Query: 1502 TTTTVTPTPTPTGTQTPTSTPITT-TTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTG 1560
            TTTT T   T   T TP+S P TT T TV  T T T       TP S+T T   + TP  
Sbjct: 2082 TTTTPT---TRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQT---SGTPPS 2135

Query: 1561 TQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTT 1620
              T  TT   T +T  P+ TP GT TP   ++TTT T   TP  TS   T  + + TT T
Sbjct: 2136 LTTTATTITATGSTTNPSSTP-GT-TPIPPVLTTTAT---TPAATSNTVTPSSALGTTHT 2190

Query: 1621 VTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESST 1680
                 T   T   ++ P S  T  T   + T+G  G             TT    P + T
Sbjct: 2191 PPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILG-------------TTHITEPSTVT 2237

Query: 1681 PQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG 1740
              T  +T+     ST  LS+  P+   T+ +PPS    P TT+ GHT +   +T T+ P 
Sbjct: 2238 SHTLAATTGTTQHSTPALSSPHPS-SRTTESPPS----PGTTTPGHTTATSRTTATATP- 2291

Query: 1741 TPTRGTTTGSSSAPTPSTVQTTTT------SAWT-------PTPTP----LSTPSIIRTT 1783
            + TR T+T   S+PT + + T  T       AW+       P P P      T S IR  
Sbjct: 2292 SKTR-TSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAA 2350

Query: 1784 GLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYN---------- 1833
            G       + + C        P  E+           V CSL   L   N          
Sbjct: 2351 GGAVCEQPLGLECRAQAQPGVPLRELGQ--------VVECSLDFGLVCRNREQVGKFKMC 2402

Query: 1834 ------------WSCPSTPS------PTPTP------SKSTPTPSKPSSTPSKPTPGTKP 1869
                          CPSTP+      P+ TP      ++ T T +   ST S  TP + P
Sbjct: 2403 FNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTP 2462



 Score =  286 bits (733), Expect = 1e-76
 Identities = 231/621 (37%), Positives = 309/621 (49%), Gaps = 84/621 (13%)

Query: 1160 TTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSS---TVLSTTPKLCCLWSDWINEDHPS 1216
            TT   T  T  T    T   T T+T   ++PTS+   TV++T  +  C WS+W++  +P 
Sbjct: 3531 TTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPM 3590

Query: 1217 SGSDDGDRETFDG-------VCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICK 1269
             G   GD +T+         VC  P  +ECR+   P + L +LGQ V+  C +  GL+C+
Sbjct: 3591 PGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVE--CSLDFGLVCR 3648

Query: 1270 NEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTP--------ITTTTT 1321
            N +Q    V     C NYEI V CC     P+T  T++T  P+ TP        +TTT T
Sbjct: 3649 NREQ----VGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTAT 3704

Query: 1322 VTPTPTPTSTQSTTP-------TPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPT 1371
             T +   T+T S+TP        P TT T   P   T T + TQ    TP  +TT  TPT
Sbjct: 3705 TTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPT 3764

Query: 1372 PTPTGTQTPTTTPITTT-------TTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQ 1424
             T +   TP ++P T T       T  TPT T + T  P+S+  TT T ++ T TPT T 
Sbjct: 3765 VT-SSKATPFSSPGTATALPALRSTATTPTAT-SFTAIPSSSLGTTWTRLSQTTTPTATM 3822

Query: 1425 ---TPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTT 1481
               TP++TP T  T+   T T T T+A       T S  TP+ TP GT   T  P TTTT
Sbjct: 3823 STATPSSTPETAHTSTVLTTTATTTRA-------TGSVATPSSTP-GTAHTTKVPTTTTT 3874

Query: 1482 --TVTPTPTPTGTQTP------TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTP 1533
              TVTP+ +P   +TP      T T  T+ +TVTP+  P  T TPT    TTTT  T + 
Sbjct: 3875 GFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSM 3934

Query: 1534 TPTGTQTPT----PTPISTTTTVTPTPTPTG-TQTPTTTPI---TTTTTVTPTPTPTGTQ 1585
                + T T    P+ I+T TT+T T + T  + TP TTPI    TTT  TP  T + T 
Sbjct: 3935 ATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAAT-SSTV 3993

Query: 1586 TPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTA-TPTPTGTQTPTMIPISTTTTV 1644
            TP++ L TT T   P  T T T   +++P +  T  TA T   +GT   T I   +T T 
Sbjct: 3994 TPSSALGTTHTPPVPNTTAT-THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGT- 4051

Query: 1645 TPTPTPTTGST--GPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP 1702
            + TP  TTG+T    P  +S  P +  T S P P ++TP  + +TS      TT  +T  
Sbjct: 4052 SHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATS-----RTT--ATAT 4104

Query: 1703 PAIEMTSTAPPSTPT-APTTT 1722
            P+   TST  PS+PT AP TT
Sbjct: 4105 PSKTRTSTLLPSSPTSAPITT 4125



 Score =  283 bits (724), Expect = 2e-75
 Identities = 234/625 (37%), Positives = 309/625 (49%), Gaps = 91/625 (14%)

Query: 1160 TTRPSTLTTFTTITLPTTPT-TFTTTTTTTTPTSSTVLSTTPKLC---CLWSDWINEDHP 1215
            TT P   T  +  T   TP+ T T+T   ++PTS+ + +     C   C WS+W++  +P
Sbjct: 2273 TTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYP 2332

Query: 1216 SSGSDDGDRETFDG-------VCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLIC 1268
              G   GD +T+         VC  P  +ECR+   P + L +LGQ V+  C +  GL+C
Sbjct: 2333 MPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVE--CSLDFGLVC 2390

Query: 1269 KNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTP--------ITTTT 1320
            +N +Q    V     C NYEI V CC     P+T  T++T  P+ TP        +TTT 
Sbjct: 2391 RNREQ----VGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTA 2446

Query: 1321 TVTPTPTPTSTQSTTP-------TPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP 1370
            T T +   T+T S+TP        P TT T   P   T T + TQ    TP  +TT  TP
Sbjct: 2447 TTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTP 2506

Query: 1371 TPTPTGTQTPTTTPITTT-------TTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGT 1423
            T T +   TP ++P T T       T  TPT T + T  P+S+  TT T ++ T TPT T
Sbjct: 2507 TVT-SSKATPFSSPGTATALPALRSTATTPTAT-SFTAIPSSSLGTTWTRLSQTTTPTAT 2564

Query: 1424 Q---TPTTTPIT--TTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPIT 1478
                TP++TP T  T+T +T T T TG          T S  TP+ TP GT   T    T
Sbjct: 2565 MSTATPSSTPETVHTSTVLTTTATTTG---------ATGSVATPSSTP-GTAHTTKVLTT 2614

Query: 1479 TTTTVTPTPTPT-GTQTPTPTAITTTT-------TVTPTPTPTGTQTPTSTPITTTTTVT 1530
            TTT  T TP+ + GT    P  I+TTT       TVTP+  P  T TPT    TTTT  T
Sbjct: 2615 TTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVAT 2674

Query: 1531 PT-PTPTGTQTPTPTPISTTTTVTPTPTPTG-----TQTPTTTPI---TTTTTVTPTPTP 1581
             +  TP+ +   + TP S TTT T T T TG     + TP TTPI    TTT  TP  T 
Sbjct: 2675 GSMATPSSSTQTSGTPPSLTTTAT-TITATGSTTNPSSTPGTTPIPPVLTTTATTPAAT- 2732

Query: 1582 TGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTA-TPTPTGTQTPTMIPIST 1640
            + T TP++ L TT T   P  T T T   +++P +  T  TA T   +GT   T I   +
Sbjct: 2733 SSTVTPSSALGTTHTPPVPNTTAT-THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPS 2791

Query: 1641 TTTVTPTPTPTTGST--GPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLL 1698
            T T + TP  TTG+T    P  +S  P +  T S P P ++TP  +R+TS      TT  
Sbjct: 2792 TGT-SHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATS-----RTT-- 2843

Query: 1699 STLPPAIEMTSTAPPSTPT-APTTT 1722
            +T  P+   TST  PS+PT AP TT
Sbjct: 2844 ATATPSKTRTSTLLPSSPTSAPITT 2868



 Score =  259 bits (661), Expect = 3e-68
 Identities = 281/908 (30%), Positives = 380/908 (41%), Gaps = 184/908 (20%)

Query: 1110 KSCVCTNSSQV--VCRPEEGKILNQTQDGAFCYWEICGPN---GTVEKHFNICSITTRPS 1164
            +  +C NS Q   +C   E ++L        C +  CGP+   GT  +     S +T P+
Sbjct: 1406 RGLMCANSQQSPPLCHDYELRVL-------CCEYVPCGPSPAPGTSPQPS--LSASTEPA 1456

Query: 1165 TLT-TFTTITLPTT-----PTTFTTTTTTTTPTSSTVLSTTPKL-----C---CLWSDWI 1210
              T T TT T  TT         T   T+ T +SS  ++ TP       C   C W++W 
Sbjct: 1457 VPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVTVTPSAPGTTTCQPRCQWTEWF 1516

Query: 1211 NEDHPSSGSDDGDRETFDGV-------CGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVS 1263
            +ED+P S    GD E++D +       C  P+DIEC++   P+ +L Q+GQKV   CDV 
Sbjct: 1517 DEDYPKSEQLGGDVESYDKIRAAGGHLCQQPKDIECQAESFPNWTLAQVGQKVH--CDVH 1574

Query: 1264 VGLICKNEDQKPGGVIPMAFCLNYEINVQCCE---C---------VTQPTTMTTTTTE-- 1309
             GL+C+N +Q+  GV  M  C NY I V CC    C          T+  T TTTTT+  
Sbjct: 1575 FGLVCRNWEQE--GVFKM--CYNYRIRVLCCSDDHCRGRATTPPPTTELETATTTTTQAL 1630

Query: 1310 ----NPTPTPITT-----TTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTT 1360
                 PT +P  T     +TT  PT +   T     + + T TT  PT TP G+  PT  
Sbjct: 1631 FSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATTGGPT-TPAGSTEPTVP 1689

Query: 1361 PITTTT-----------------------TVTPTPTPTGTQTPTTT-------PITTTTT 1390
             + T+T                       T+ PT   T    PT T       P+TT+  
Sbjct: 1690 GVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLA 1749

Query: 1391 VTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT------ 1444
             T T   + +Q  TSTP T TT    T T T   T    P    T       PT      
Sbjct: 1750 PTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGG 1809

Query: 1445 ------------GTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG- 1491
                        G     P +I   +   P  +        T  + T  T       TG 
Sbjct: 1810 DMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGLTCK-NEDQTGR 1868

Query: 1492 -----------------TQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPT 1534
                             +  P+  A ++T T + TP  T   T  +T  TTT +   T T
Sbjct: 1869 FNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTAT 1928

Query: 1535 PTGTQTPTPTPISTTTTVTPTPTPTGTQ-TPTTTPITTT-------TTVTPTPTPTGTQT 1586
            PT T    P P   TTT T TPT T ++ TP+++P T T       T  TPT T   T  
Sbjct: 1929 PTSTLRTAPPPKVLTTTAT-TPTVTSSKATPSSSPGTATALPALRSTATTPTATSV-TPI 1986

Query: 1587 PTTVLITTTTTMTPTPTPTSTKSTTV---TPIT--TTTTVTATPTPTGTQTPTMIPISTT 1641
            P++ L TT T ++ T TPT+T ST     TP T  T+T +TAT T TG       P ST 
Sbjct: 1987 PSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTP 2046

Query: 1642 TTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSP----------- 1690
             T   T  PTT +TG     S++P   LT       ++TP T  ST +P           
Sbjct: 2047 GTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTAT 2106

Query: 1691 -LTESTTLLST----LPPAIEMTSTAPPS-TPTAPTTTSGGHTLSP--PPSTTTSPPGTP 1742
             LT +TT ++T     P +   TS  PPS T TA T T+ G T +P   P TT  PP   
Sbjct: 2107 VLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVL- 2165

Query: 1743 TRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTY 1802
               TTT ++ A T +TV  T +SA   T TP   P+ + TT  R  P S         T 
Sbjct: 2166 ---TTTATTPAATSNTV--TPSSALGTTHTP-PVPNTMATTHGRSLPPS------SPHTV 2213

Query: 1803 YAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSK 1862
                    +G  G T    + +   T+  +  +  +  +   TP+ S+P PS   +T S 
Sbjct: 2214 RTAWTSATSGILGTT----HITEPSTVTSHTLAATTGTTQHSTPALSSPHPSS-RTTESP 2268

Query: 1863 PTPGTKPP 1870
            P+PGT  P
Sbjct: 2269 PSPGTTTP 2276



 Score =  206 bits (525), Expect = 2e-52
 Identities = 249/856 (29%), Positives = 324/856 (37%), Gaps = 153/856 (17%)

Query: 1103 VPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTR 1162
            VP  E  +   C+    +VCR       N+ Q G F   ++C      E     C+    
Sbjct: 2928 VPLRELGQVVECSLDFGLVCR-------NREQVGKF---KMCF---NYEIRVFCCNYGHC 2974

Query: 1163 PSTLTTFTTITLPTTP------TTFTTTTTTTTPTSSTVL-STTPKLCCLWSDWINEDHP 1215
            PST  T +T T  +TP      T  TT  TTT  T ST + S+TP               
Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTP--------------- 3019

Query: 1216 SSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQKP 1275
                  G       +          S K    S  +    + ++   +      +    P
Sbjct: 3020 ------GTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIP 3073

Query: 1276 GGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPT--PTPITTTTTVTPTPTPTSTQS 1333
               +     L  +         T   + T  TT   T   T  TTT   +   TP+ST  
Sbjct: 3074 SFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPG 3133

Query: 1334 TTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1393
            TT      TT  T T     T TP++TP TT     P+ T T      T P  +T T + 
Sbjct: 3134 TTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTAT-----VTVPTGSTATASS 3188

Query: 1394 TPTPTGTQTPTSTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPT-------- 1444
            T    GT    ++  TT T ++   TP+ +  T T  P   +T  TPT T          
Sbjct: 3189 TRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSL 3248

Query: 1445 GT------QAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTT------VTPTPTP-TG 1491
            GT      Q  TPTA  T ST TP+ TP    T T    TTTTT       TP+ TP T 
Sbjct: 3249 GTAWTRLSQTTTPTA--TMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTA 3306

Query: 1492 TQTPTPTAITTTTTVTPTPTPTGTQTP------TSTPITTTTTVTPTPTPTGTQTPTPTP 1545
              T  PT  TT  T TP+ +P    TP      T+TP T  +TVTP+  P  T T T   
Sbjct: 3307 HTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLT 3366

Query: 1546 ISTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTP--TP 1602
             +TTT  T +  TP+ +   + TP + TTT T T T TG+        TT  + TP  TP
Sbjct: 3367 TTTTTVATGSMATPSSSTQTSGTPPSLTTTAT-TITATGS--------TTNPSSTPGTTP 3417

Query: 1603 TPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTS 1662
             P    +T  TP  T++TVT +     T TP  +P +T TT   +  P++  T     TS
Sbjct: 3418 IPPVLTTTATTPAATSSTVTPSSALGTTHTPP-VPNTTATTHGRSLPPSSPHTVRTAWTS 3476

Query: 1663 TAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT 1722
                   TT    P + T  T  +T+S    ST  LS+  P+   T+ +PPS    P TT
Sbjct: 3477 ATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPS-SRTTESPPS----PGTT 3531

Query: 1723 SGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTT----TSAWT-------PTP 1771
            + GHT     +T T+ P      T   SS    P T   TT      AW+       P P
Sbjct: 3532 TPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMP 3591

Query: 1772 TP----LSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSC 1827
             P      T S IR  G       + + C        P  E+           V CSL  
Sbjct: 3592 GPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQ--------VVECSLDF 3643

Query: 1828 TLEFYN----------------------WSCPSTP--SPTPTPS----------KSTPTP 1853
             L   N                        CPSTP  S T TPS          K T T 
Sbjct: 3644 GLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTA 3703

Query: 1854 SKPSSTPSKPTPGTKP 1869
            +   ST S  TP + P
Sbjct: 3704 TTTESTGSTATPSSTP 3719



 Score =  202 bits (513), Expect = 5e-51
 Identities = 248/829 (29%), Positives = 321/829 (38%), Gaps = 161/829 (19%)

Query: 1160 TTRPSTLT------TFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINED 1213
            TTR ST+T      T  T T+ TT TT   T +  TP+SST  S TP      +  I   
Sbjct: 3344 TTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTIT-- 3401

Query: 1214 HPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQ 1273
              ++GS      T  G    P  +   +      S             V+          
Sbjct: 3402 --ATGSTTNPSST-PGTTPIPPVLTTTATTPAATS-----------STVTPSSALGTTHT 3447

Query: 1274 KPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVT---PTPTPTS 1330
             P   +P      +  ++      T  T  T+ T+     T IT  +TVT   P  T ++
Sbjct: 3448 PP---VPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTST 3504

Query: 1331 TQSTTPT-----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 1380
            TQ +TP      P + TT   P+P   GT TP  T  T+ TT T TP+ T T T     P
Sbjct: 3505 TQHSTPALSSPHPSSRTTESPPSP---GTTTPGHTRGTSRTTATATPSKTRTSTLLPSSP 3561

Query: 1381 TTTPITTTTTVT---------------PTPTPTGTQTPTSTPITTTTTVT---PTPTPTG 1422
            T+ PITT  T                 P P P+G    T + I          P      
Sbjct: 3562 TSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECR 3621

Query: 1423 TQTPTTTPITTTTTVTPTPTPTG-------------------------TQAPTPTAITTT 1457
             Q     P+     V       G                              P+   T+
Sbjct: 3622 AQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATS 3681

Query: 1458 STVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTP--T 1509
            ST TP+ TP      T   T  TT  +T +T TP+ TP  T   T  + T T TV    T
Sbjct: 3682 STATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGST 3741

Query: 1510 PTPTGTQTPTSTPITTTTTVTPTPTPT--------GTQTPTPTPISTTTTVTPT------ 1555
             T + TQ    TP  +TT  TPT T +        GT T  P   ST TT T T      
Sbjct: 3742 ATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIP 3801

Query: 1556 PTPTGTQ----TPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTT------MTPTPTPT 1605
             +  GT     + TTTP  T +T TP+ TP    T T +  T TTT       TP+ TP 
Sbjct: 3802 SSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTP- 3860

Query: 1606 STKSTTVTPITTTTTVTATPTPT-GTQTPTMIPISTTTTVTP-----TPTPTTGSTGPPT 1659
             T  TT  P TTTT  T TP+ + GT     + ISTTTT T      TP+   G+T  PT
Sbjct: 3861 GTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPT 3920

Query: 1660 HTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLL----STLPPAIEMTSTAPP-- 1713
              +T      T S   P SST QTS +  S +T +TT+     +T P +   T+  PP  
Sbjct: 3921 VLTTTTTTVATGSMATPSSST-QTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVL 3979

Query: 1714 -STPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAP-TPSTVQTTTTSAWTPT- 1770
             +T T P  TS   T S    TT +PP   T  TT G S +P +P TV+T  TSA + T 
Sbjct: 3980 TTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTL 4039

Query: 1771 -PTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTL 1829
              T ++ PS    TG    P++                     T G T +      S   
Sbjct: 4040 GTTHITEPS----TGTSHTPAA---------------------TTGTTQHSTPALSSPHP 4074

Query: 1830 EFYNWSCPSTPSPTPTPSKSTPTP-SKPSSTPSKPTPGTKPPECPDFDP 1877
                   P +P  T TP  +T T  +  ++TPSK    T  P  P   P
Sbjct: 4075 SSRTTESPPSPG-TTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAP 4122



 Score =  192 bits (489), Expect = 3e-48
 Identities = 233/823 (28%), Positives = 320/823 (38%), Gaps = 184/823 (22%)

Query: 1160 TTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGS 1219
            T   ST T+ T  +L TT TT T T +TT P+S+   +  P +    +       P++ S
Sbjct: 2122 TPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATT-----PAATS 2176

Query: 1220 DDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLV-CDVSVGLICKNEDQKPGGV 1278
            +     +  G    P      +              V+      + G++      +P  V
Sbjct: 2177 NTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTV 2236

Query: 1279 IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPIT---------TTTTVTPTPTPT 1329
                              ++ P   + TT   P+P   T         TT T TP+ T T
Sbjct: 2237 TSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRT 2296

Query: 1330 ST---QSTTPTPITTTTTVT---------------PTPTPTGTQTPTTTPITTTTTVT-- 1369
            ST    S T  PITT  T+                P P P+G    T + I         
Sbjct: 2297 STLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCE 2356

Query: 1370 -PTPTPTGTQTPTTTPITTTTTVTP----------------------------------- 1393
             P       Q     P+     V                                     
Sbjct: 2357 QPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH 2416

Query: 1394 ---TPTPTGTQTPTSTPITT------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 1444
               TP  + T  P+STP TT      TTT T T +   T TP++TP TT     P+ T T
Sbjct: 2417 CPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTAT 2476

Query: 1445 GTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTT 1504
             T  PT +  T +ST     TP    T  TTP  T++  TP  +P GT T  P   +T T
Sbjct: 2477 VT-VPTGSTATASSTQATAGTPH-VSTTATTPTVTSSKATPFSSP-GTATALPALRSTAT 2533

Query: 1505 TVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTP 1564
            T T T   + T  P+S+  TT T ++ T TPT T + T TP ST  TV    T T   T 
Sbjct: 2534 TPTAT---SFTAIPSSSLGTTWTRLSQTTTPTATMS-TATPSSTPETVH---TSTVLTTT 2586

Query: 1565 TTTPITTTTTVTPTPTPTGTQTPTTVLITTTT--TMTPTPTPTSTK------STTVTPIT 1616
             TT   T +  TP+ TP GT   T VL TTTT  T TP+ +P + +      STT TP T
Sbjct: 2587 ATTTGATGSVATPSSTP-GTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTT 2645

Query: 1617 TTTTVTATPTPTGTQTPTMIPISTTTTVT---PTPTPTTGSTG-PPTHTSTAPIAELTTS 1672
              +TVT +  P  T TPT++  +TTT  T    TP+ +T ++G PP+ T+TA     T S
Sbjct: 2646 RGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGS 2705

Query: 1673 NPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPP 1732
               P SSTP T+                +PP +  T+T P +T +  T +S         
Sbjct: 2706 TTNP-SSTPGTT---------------PIPPVLTTTATTPAATSSTVTPSSA-------L 2742

Query: 1733 STTTSPPGTPTRGTTTGSSSAPT-PSTVQTTTTSAWTPT--PTPLSTPSIIRTTGLRPYP 1789
             TT +PP   T  TT G S +P+ P TV+T  TSA + T   T ++ PS    TG    P
Sbjct: 2743 GTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPS----TGTSHTP 2798

Query: 1790 SSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCP--STPSPTPTPS 1847
            ++                     T G T +               S P  S+P P+   +
Sbjct: 2799 AA---------------------TTGTTQH---------------STPALSSPHPSSRTT 2822

Query: 1848 KSTPTP-------------SKPSSTPSKPTPGTKPPECPDFDP 1877
            +S P+P             +  ++TPSK    T  P  P   P
Sbjct: 2823 ESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAP 2865



 Score =  192 bits (487), Expect = 5e-48
 Identities = 238/824 (28%), Positives = 313/824 (37%), Gaps = 139/824 (16%)

Query: 1158 SITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSS 1217
            S+ T  ST  T  T  +PTT    TTT  T TP+SS   + TP +      WI+     +
Sbjct: 2038 SVATPSSTPGTAHTTKVPTT----TTTGFTATPSSSPGTALTPPV------WISTTTTPT 2087

Query: 1218 --------GSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCD---VSVGL 1266
                     S  G   T   +      +   S+  P  S +  G    L      ++   
Sbjct: 2088 TRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATG 2147

Query: 1267 ICKNEDQKPGGV-IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPT 1325
               N    PG   IP                VT  + + TT T  P P  + TT   +  
Sbjct: 2148 STTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTP-PVPNTMATTHGRSLP 2206

Query: 1326 PTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---------------VTP 1370
            P+   T  T  T  T+    T   T   T T  T   TT TT                T 
Sbjct: 2207 PSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTE 2266

Query: 1371 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----PTSTPITTTTTVT---------- 1415
            +P   GT TP  T  T+ TT T TP+ T T T     PTS PITT  T+           
Sbjct: 2267 SPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEW 2326

Query: 1416 -----PTPTPTGTQTPTTTPITTTTTVT---PTPTPTGTQAPTPTAITTTSTVTPTPTPT 1467
                 P P P+G    T + I          P       QA     +     V       
Sbjct: 2327 LDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDF 2386

Query: 1468 GTQTPT--------------------------TTPITTTTTVTPTPTPTGTQTPTPTAIT 1501
            G                               +TP T++T + P+ TP  T   T     
Sbjct: 2387 GLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAM-PSSTPGTTWILT----E 2441

Query: 1502 TTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGT 1561
             TTT T T +   T TP+STP TT     P+ T T T      P  +T T + T    GT
Sbjct: 2442 LTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVT-----VPTGSTATASSTQATAGT 2496

Query: 1562 ---QTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTP---TPTPTSTKSTTVTPI 1615
                T  TTP  T++  TP  +P GT T    L +T TT T    T  P+S+  TT T +
Sbjct: 2497 PHVSTTATTPTVTSSKATPFSSP-GTATALPALRSTATTPTATSFTAIPSSSLGTTWTRL 2555

Query: 1616 TTTTTVTAT-PTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHT-----STAPIAEL 1669
            + TTT TAT  T T + TP  +  ST  T T T T  TGS   P+ T     +T  +   
Sbjct: 2556 SQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTT 2615

Query: 1670 TTSNPPPESSTPQTSR-------STSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT 1722
            TT      SS+P T+R       +T++P T  +T+    P +I  T+  P    T  TT 
Sbjct: 2616 TTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTV---TPSSIPGTTHTPTVLTTTTTTV 2672

Query: 1723 SGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSII-R 1781
            + G   +P  ST TS  GTP   TTT ++   T ST   ++T   TP P  L+T +    
Sbjct: 2673 ATGSMATPSSSTQTS--GTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPA 2730

Query: 1782 TTGLRPYPSSVLICC----VLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCP 1837
             T     PSS L       V N T    G  +   +          + S TL   + + P
Sbjct: 2731 ATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEP 2790

Query: 1838 ST-PSPTP----------TPSKSTPTPSKPSSTPSKPTPGTKPP 1870
            ST  S TP          TP+ S+P PS   +T S P+PGT  P
Sbjct: 2791 STGTSHTPAATTGTTQHSTPALSSPHPSS-RTTESPPSPGTTTP 2833



 Score =  187 bits (476), Expect = 9e-47
 Identities = 198/659 (30%), Positives = 275/659 (41%), Gaps = 123/659 (18%)

Query: 1301 TTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQ----T 1356
            +T TT T  +   TP ++  T T  P   + +ST  TP  T+ T  P+ +  GT     +
Sbjct: 3201 STATTPTVISSRATPSSSPGTATALP---ALRSTATTPTATSVTAIPSSS-LGTAWTRLS 3256

Query: 1357 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTSTPITT 1410
             TTTP  T +T TP+ TP    T T    TTTTT       TP+ TP GT   T  P TT
Sbjct: 3257 QTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTP-GTAHTTKVPTTT 3315

Query: 1411 TT--TVTPTPTPTGTQTP------TTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTP 1462
            TT  T TP+ +P    TP      TTTP T  +TVTP+  P  T   T T +TTT+T   
Sbjct: 3316 TTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTH--TATVLTTTTTTVA 3373

Query: 1463 T---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPT 1519
            T    TP+ +   + TP + TTT T T T TG+ T  P++   TT + P  T T T    
Sbjct: 3374 TGSMATPSSSTQTSGTPPSLTTTAT-TITATGS-TTNPSSTPGTTPIPPVLTTTAT---- 3427

Query: 1520 STPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1579
             TP  T++TVTP+     T TP P P +T TT   +  P+   T  T   + T+ +  T 
Sbjct: 3428 -TPAATSSTVTPSSALGTTHTP-PVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTT 3485

Query: 1580 --TPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIP 1637
              T   T T  T   TT+TT   TP  +S       P  ++ T  + P+P GT TP    
Sbjct: 3486 HITEPSTVTSHTPAATTSTTQHSTPALSS-------PHPSSRTTESPPSP-GTTTPGHTR 3537

Query: 1638 ISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPES--------STPQTSRS--- 1686
             ++ TT T TP+ T  ST  P+  ++API  + T+   P+         S P    S   
Sbjct: 3538 GTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGD 3597

Query: 1687 --TSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPT------------------------ 1720
              T S +  +   +   P  +E  + A P  P                            
Sbjct: 3598 FDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFK 3657

Query: 1721 ----------TTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPT 1770
                        + GH  S P +++T+ P      +T G++   T  T   TTT +   T
Sbjct: 3658 MCFNYEIRVFCCNYGHCPSTPATSSTATP-----SSTPGTTWILTKLTTTATTTESTGST 3712

Query: 1771 PTPLSTPSIIRTTGLRPYPSSVLICCV-LNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTL 1829
             TP STP    TT +   PS+     V    T  A   +   GT        + S + T 
Sbjct: 3713 ATPSSTPG---TTWILTEPSTTATVTVPTGSTATASSTQATAGT-------PHVSTTAT- 3761

Query: 1830 EFYNWSCPSTPSPTPTPSKSTP--TPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWW 1886
                       +PT T SK+TP  +P   ++ P+  +  T P        P     T W
Sbjct: 3762 -----------TPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTW 3809



 Score =  172 bits (437), Expect = 3e-42
 Identities = 174/549 (31%), Positives = 229/549 (41%), Gaps = 69/549 (12%)

Query: 1103 VPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTR 1162
            VP  E  +   C+    +VCR       N+ Q G F   ++C      E     C+    
Sbjct: 3628 VPLRELGQVVECSLDFGLVCR-------NREQVGKF---KMCF---NYEIRVFCCNYGHC 3674

Query: 1163 PSTLTTFTTITLPTTP------TTFTTTTTTTTPTSSTVL-STTPKLCCLWSDWINEDHP 1215
            PST  T +T T  +TP      T  TTT TTT  T ST   S+TP      + WI  +  
Sbjct: 3675 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTP-----GTTWILTEPS 3729

Query: 1216 SSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQKP 1275
            ++ +      T      A       +   PH+S              +V          P
Sbjct: 3730 TTAT-----VTVPTGSTATASSTQATAGTPHVS--------TTATTPTVTSSKATPFSSP 3776

Query: 1276 GGVIPMAFCLNYEINVQCCECVTQPTTM--TTTTTENPTPTPITTTTTVTPTPTPTSTQS 1333
            G    +    +             P++   TT T  + T TP  T +T TP+ TP +  +
Sbjct: 3777 GTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHT 3836

Query: 1334 TTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-TQTPTTTPITTTTTVT 1392
            +T      TTT T T       TP++TP T  TT  PT T TG T TP+++P T      
Sbjct: 3837 ST----VLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTAR---- 3888

Query: 1393 PTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---PTP-TPTGTQA 1448
               TP    + T+TP T+ +TVTP+  P  T TPT    TTTT  T    TP + T T  
Sbjct: 3889 ---TPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSG 3945

Query: 1449 PTPTAITTTSTVTPTPTPTG-TQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVT 1507
              P+ ITT +T+T T + T  + TP TTPI    T T T     + T TP++   TT   
Sbjct: 3946 TPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTP 4005

Query: 1508 PTPTPT----GTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQ- 1562
            P P  T    G     S+P T  T  T   + T   T    P ST T+ TP  T   TQ 
Sbjct: 4006 PVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEP-STGTSHTPAATTGTTQH 4064

Query: 1563 -TPTTTPITTTTTVTPTPTPTGTQTP--TTVLITTTTTMTPTPTPTST---KSTTVTPIT 1616
             TP  +    ++  T +P   GT TP  TT    TT T TP+ T TST    S T  PIT
Sbjct: 4065 STPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPIT 4124

Query: 1617 TTTTVTATP 1625
            T  T    P
Sbjct: 4125 TVVTTGCEP 4133



 Score =  127 bits (320), Expect = 1e-28
 Identities = 120/459 (26%), Positives = 185/459 (40%), Gaps = 84/459 (18%)

Query: 757  CHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVT 816
            C   CS++G  HY TFDG  Y F G+C+YV +++    ++  G+ S+  +N  C  +   
Sbjct: 5074 CECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREI---HARFGNLSLYLDNHYCTASATA 5130

Query: 817  ----CSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWD 872
                C +A+ I     ++ L     +V  ++EG  + +    V       S  G++V   
Sbjct: 5131 AAARCPRALSIHYKSMDIVLTVT--MVHGKEEGL-ILFDQIPVSSGF---SKNGVLVSVL 5184

Query: 873  KRTTVFIKL-----APSYKGTVC--------------GLCGNFDHRSNNDFTTRDHMVVS 913
              TT+ + +     + ++ G V               G CG   +   +D   RD    +
Sbjct: 5185 GTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAA 5244

Query: 914  SELDFGNSW------------------KEAPTCPDVST-NPEPCSLNPHRRSWAEKQCSI 954
            S  D   +W                    +P  P  ST  P PC   P         C +
Sbjct: 5245 SCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQP--------LCDL 5296

Query: 955  LKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWR- 1013
            + S VF+ CH+ V P PF+ AC+ D C     G  E  C ++ +YA+ C   G C  WR 
Sbjct: 5297 MLSQVFAECHNLVPPGPFFNACISDHCR----GRLEVPCQSLEAYAELCRARGVCSDWRG 5352

Query: 1014 -TPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDR 1072
             T  LC + C    PP +    Y+PCG     TC + N   S       EGC+  CP+D+
Sbjct: 5353 ATGGLCDLTC----PPTKV---YKPCGPIQPATCNSRN--QSPQLEGMAEGCF--CPEDQ 5401

Query: 1073 PIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSS-QVVCRP----EEG 1127
             ++   +  CV A  C C   D  +P          C+SCVC   S  V C+P     +G
Sbjct: 5402 ILFNAHMGICVQA--CPCVGPD-GFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQG 5458

Query: 1128 KILNQTQDGAFCYWEICGPNGTVEKHFNICSITTRPSTL 1166
            +     + G          N    +   +C+ TT P +L
Sbjct: 5459 QPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSL 5497



 Score =  118 bits (295), Expect = 9e-26
 Identities = 151/617 (24%), Positives = 236/617 (38%), Gaps = 119/617 (19%)

Query: 1796 CVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSK 1855
            C  + T  APGE V++   G  C      LSC             S   +   + P    
Sbjct: 757  CYAHGTVLAPGEVVHDE--GAVCSCTGGKLSCL----------GASLQKSTGCAAPMVYL 804

Query: 1856 PSSTPSKPTPGTKP-PECPDFD--------------PPRQENETWWLC----DCFMATCK 1896
              S  S  TPG +    C   D              PP   ++    C    DC    C 
Sbjct: 805  DCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDC---PCV 861

Query: 1897 YNNTV----EIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTF 1952
            +N       E ++V+C      TC N     R E     C H  C   C  +GD H++TF
Sbjct: 862  HNEATYKPGETIRVDCNTC---TCRNR----RWE-----CSHRLCLGTCVAYGDGHFITF 909

Query: 1953 DGLYYSYQGNCTYVLVEEI---SPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVL 2009
            DG  YS++G+C Y+L ++    + +   F +  +N  C      +C + + +  E+ E++
Sbjct: 910  DGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTG-TTCSKAIKLFVESYELI 968

Query: 2010 IKTVHMMPMQVQVQVNRQAVAL------PYKKYGLEVYQSGINYVVDIPELGVLVSYN-G 2062
            ++           +   +AVA       PYK     +   GI  V++    G+ VS++  
Sbjct: 969  LQ-----------EGTFKAVARGPGGDPPYK-----IRYMGIFLVIETH--GMAVSWDRK 1010

Query: 2063 LSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCP 2122
             S  +RL +  +     G CG   +   +D    S  +V +     + W ++    P CP
Sbjct: 1011 TSVFIRL-HQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLS----PSCP 1065

Query: 2123 HSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC 2182
              +   K P           P +       C ++    FA C + V    YY+ACV D+C
Sbjct: 1066 -DALAPKDPCT-------ANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDAC 1117

Query: 2183 FM-PGSSLE--CASLQAYAALCAQQNICLDWRNHTHGACLVECPSHR-------EYQACG 2232
                G   E  C ++ AYA  C    +C+ WR  T   C + C  +         YQ CG
Sbjct: 1118 ACDSGGDCECFCTAVAAYAQACHDAGLCVSWR--TPDTCPLFCDFYNPHGGCEWHYQPCG 1175

Query: 2233 PAEEPTCKSSSSQ-QNNTVLVEGCF--CPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGE 2289
                 TC++ S     +   +EGC+  CP     +      CV  CGC   D    + G 
Sbjct: 1176 APCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGA 1235

Query: 2290 HFEF--DCKNCVCLEGGSGIIC----QPKRCSQKPVTHCVEDGTYLATEVNPADTCCNIT 2343
                  +C++C C    SGI C    +   C+ +  T+  +D  Y  T+   A   C I 
Sbjct: 1236 RVPTAENCQSCNCTP--SGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGA---CLIA 1290

Query: 2344 VCKCNTSLCKEKPSVCP 2360
            +C  N ++ + K   CP
Sbjct: 1291 ICGSNGTIIR-KAVACP 1306



 Score =  115 bits (288), Expect = 6e-25
 Identities = 124/519 (23%), Positives = 200/519 (38%), Gaps = 65/519 (12%)

Query: 1915 TCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPS 1974
            TCS GL           C    C   C+  G  H  T+D   Y   G+C+YVL ++ + S
Sbjct: 411  TCSGGLWQ---------CQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADS 461

Query: 1975 VDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKT-----VHMMPMQVQVQVNRQAV 2029
              +F V  +   C   D  +C + + +  +  +  I+      V +  +  Q+ ++   +
Sbjct: 462  --SFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANI 519

Query: 2030 ALPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRL-PYHRFGNNTKGQCGTCTNT 2088
             L        V Q+G+   + +  + ++  +      VRL P H+      G CG     
Sbjct: 520  TLFTPSSFFIVVQTGLGLQLLVQLVPLMQVF------VRLDPAHQ--GQMCGLCGNFNQN 571

Query: 2089 TSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCT 2148
             +DD    SG + +   A A+ W     ++  C ++ ++ + P            H    
Sbjct: 572  QADDFTALSGVVEATGAAFANTW----KAQAACANARNSFEDPCSLSVENENYARH---- 623

Query: 2149 PSPLCQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALCAQQN 2205
                C  + D  S F++CH+++ P+ ++  C+FD+C    S    CA+L +Y   CA + 
Sbjct: 624  ---WCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKG 680

Query: 2206 ICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQ----QNNTVLVEGCFCPEG 2260
            + L DWR+      +  CP  + Y     A +PTC+  S        + V V+GC CP G
Sbjct: 681  VQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAG 740

Query: 2261 TMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVT 2320
            T     G  V  + C C     V    GE    +   C C  G    +      S +  T
Sbjct: 741  TFLNDAGACVPAQECPCYAHGTVLAP-GEVVHDEGAVCSCTGGKLSCL----GASLQKST 795

Query: 2321 HCVEDGTYLATEVNPADT-------CCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGR 2373
             C     YL    + A T        C+     C ++ C     VCP G         G 
Sbjct: 796  GCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHC-VSGCVCPPGLVSDGS---GG 851

Query: 2374 CCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDK 2412
            C      E    CVH  A Y+PG  +    C  C C ++
Sbjct: 852  CI----AEEDCPCVHNEATYKPGETI-RVDCNTCTCRNR 885



 Score = 98.2 bits (243), Expect = 9e-20
 Identities = 107/403 (26%), Positives = 156/403 (38%), Gaps = 53/403 (13%)

Query: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000
            C+ WGD HY TFDG  + + G C YV  E    + ++F V +              R L+
Sbjct: 77   CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQL-------------RRGLV 123

Query: 2001 -VRHETQEVLIKTVHMM--PMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVL 2057
              R     V+IK   ++       V +N Q   LPY + GL V QSG +Y+     L + 
Sbjct: 124  GSRPVVTRVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSG-DYIKVSIRLVLT 182

Query: 2058 VSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPS 2117
              +NG   ++     ++ N T G CG      + +        ++  +    Q L  D  
Sbjct: 183  FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKL--DGP 240

Query: 2118 KPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDAC 2177
               CP          + +P G  T     C      + +    FA+CHALV    Y  AC
Sbjct: 241  TEQCP--------DPLPLPAGNCTDEEGICH-----RTLLGPAFAECHALVDSTAYLAAC 287

Query: 2178 VFDSCFMPGSSLECASLQAYAALCAQQ-NICLDWRNHTHGACLVECPSHREYQACGPAEE 2236
              D C  P  +  CA+   Y+  CA       +WR      C   CP + ++Q CG    
Sbjct: 288  AQDLCRCP--TCPCATFVEYSRQCAHAGGQPRNWR--CPELCPRTCPLNMQHQECGSPCT 343

Query: 2237 PTCKS-SSSQQNNTVLVEGCFCPEGTM-----NYAPGFDVCVKTCGCV--GPDNVPREFG 2288
             TC +   +Q      V+GCFCP G       +      + +  C C   G    P   G
Sbjct: 344  DTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSP---G 400

Query: 2289 EHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLAT 2331
              F   C +C C   G    CQ   C   P T  V+ G +++T
Sbjct: 401  TSFNTTCSSCTC--SGGLWQCQDLPC---PGTCSVQGGAHIST 438



 Score = 80.9 bits (198), Expect = 2e-14
 Identities = 85/332 (25%), Positives = 126/332 (37%), Gaps = 38/332 (11%)

Query: 36   VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGV---- 91
            +CS WG  HY TFDG  + F G C Y    +    +   +++L      A A A      
Sbjct: 5077 ICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAARCP 5136

Query: 92   ESILLTIKDDTIYLT--------RHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYS--RA 141
             ++ +  K   I LT          L + +   VS+     G+L+      T        
Sbjct: 5137 RALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPAL 5196

Query: 142  GLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKI-- 199
            G+++ +N +        + F N+T G CG     Q       DG   +  +  +M K   
Sbjct: 5197 GVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCK--DMAKTWL 5254

Query: 200  --NQPDVVCEDPE------EEVAPASCSEHRAECER-----LLTAEAFADCQDLVPLEPY 246
              +     C  P          AP S +     C       L+ ++ FA+C +LVP  P+
Sbjct: 5255 VPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPF 5314

Query: 247  LRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVY 306
              AC  D CR  G     C ++  ++  C  A G   +WR AT  +      TCP   VY
Sbjct: 5315 FNACISDHCR--GRLEVPCQSLEAYAELC-RARGVCSDWRGATGGL---CDLTCPPTKVY 5368

Query: 307  LESGSPCMDTCSHLEVSSLCEEHRMDGCFCPE 338
               G     TC+    S    E   +GCFCPE
Sbjct: 5369 KPCGPIQPATCNSRNQSPQL-EGMAEGCFCPE 5399



 Score = 79.3 bits (194), Expect = 5e-14
 Identities = 97/398 (24%), Positives = 140/398 (35%), Gaps = 55/398 (13%)

Query: 426  QGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYA 485
            +G CG     + DD     G   A+    A TW    S  D   W          +A+ A
Sbjct: 5221 EGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGC-WAPTGTP---PTASPA 5276

Query: 486  EHWCSLLKKTETP------------FGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAAL 533
                S    T  P            F  CH+ V P  ++  C  D  +C+   +  C +L
Sbjct: 5277 APVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISD--HCRGRLEVPCQSL 5334

Query: 534  SSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGF 593
             +YA  C A+GV    WR         +CP ++V+         TC S +++    LEG 
Sbjct: 5335 EAYAELCRARGVCS-DWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQ--LEGM 5391

Query: 594  APVDGCGCPDHTFLDEKGRCVPLAKCSCY-HRGLYLEAGDVVVRQEERCVCRDG--RLHC 650
            A  +GC CP+   L      + +  C C    G     G+  V   + CVC +G   + C
Sbjct: 5392 A--EGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQC 5449

Query: 651  RQIRLIGQSCTAPKIHMDCSNLTALATSKPRALS--CQTLAAGYYHTECVSGC-VCPDG- 706
            + +    Q    P     C+    +  ++PRA +  C         T C     VCP G 
Sbjct: 5450 KPLPCDAQGQPPP-----CNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQ 5504

Query: 707  --LMDDGRGGCVVEKECP---CVHNNDLYSSGAKI--KVDCNTCTCKRG-----RWVCTQ 754
              +     G C     C    C +N   Y  GA     + C+ CTC  G        C +
Sbjct: 5505 ESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQE 5564

Query: 755  AVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYC 792
              C+ T    G         +Y    G C    VQ  C
Sbjct: 5565 DACNNTTCPQGF--------EYKRVAGQCCGECVQTAC 5594



 Score = 35.4 bits (80), Expect = 0.75
 Identities = 26/100 (26%), Positives = 37/100 (37%), Gaps = 16/100 (16%)

Query: 2337 DTCCNITVCKCNTSLCKEKPSVCPLGFE--VKSKMVPGRCCPFYWCESKGVCVHGNAEYQ 2394
            DTC N    +     C +    CP G    V   +    C P   C     C HG   Y 
Sbjct: 344  DTCSNPQRAQLCEDHCVDG-CFCPPGRSCTVLDDITHSGCLPLGQCP----CTHGGRTYS 398

Query: 2395 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434
            PG+  +++ C  C C+          +  C  +PC  +CS
Sbjct: 399  PGTS-FNTTCSSCTCSG--------GLWQCQDLPCPGTCS 429



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 7/71 (9%)

Query: 1796 CVLNDTYYAPGEEVYNGTYG-DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTP------SK 1848
            C   D  Y+  + +YN T G   C    C  + T+     +CP TP+ TP          
Sbjct: 1264 CTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPGTPATTPFTFTTAWVPH 1323

Query: 1849 STPTPSKPSST 1859
            ST +P+ P ST
Sbjct: 1324 STTSPALPVST 1334



 Score = 32.7 bits (73), Expect = 4.9
 Identities = 19/41 (46%), Positives = 23/41 (56%)

Query: 1158 SITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLST 1198
            S  T  STL T  T  + TT  T  T T +T P+SSTV +T
Sbjct: 4866 STATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTT 4906



 Score = 32.3 bits (72), Expect = 6.4
 Identities = 21/49 (42%), Positives = 28/49 (57%), Gaps = 3/49 (6%)

Query: 1156 ICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTP--TSSTV-LSTTPK 1201
            + + T   ST T+FT I   T  TT+T    TTTP  T ST+  S+TP+
Sbjct: 4740 VLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPE 4788


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 1135 bits (2936), Expect = 0.0
 Identities = 623/1500 (41%), Positives = 810/1500 (54%), Gaps = 207/1500 (13%)

Query: 32   HGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGV 91
            H   VCSTWG+FHYKTFDGDVFRFPGLC+Y F+  CR +Y++F V L+RG     +   V
Sbjct: 728  HNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRG--LVGSRPVV 785

Query: 92   ESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNRED 151
              +++  +   +  +    ++NG     P+   GLL+E+S  Y KV  R  LT +WN ED
Sbjct: 786  TRVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGED 845

Query: 152  ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCEDPEE 211
            + +LELD K+ N TCGLCGD+NGL +++EF +     +PL+FGN+QK++ P   C DP  
Sbjct: 846  SALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLP 905

Query: 212  EVAPASCSE-----HR-------AECERLLTAEAF--ADCQDLV--PLEP------YLRA 249
              A  +C++     HR       AEC  L+ + A+  A  QDL   P  P      Y R 
Sbjct: 906  LPA-GNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCATFVEYSRQ 964

Query: 250  C------------------------QQDRCRCPGGDTCV--------------------- 264
            C                        Q   C  P  DTC                      
Sbjct: 965  CAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPG 1024

Query: 265  --CSTVAEFSRQ---------CSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPC 313
              C+ + + +           C+H GGR   +   TS  +  +S TC G L   +   PC
Sbjct: 1025 RSCTVLDDITHSGCLPLGQCPCTH-GGR--TYSPGTSFNTTCSSCTCSGGLWQCQD-LPC 1080

Query: 314  MDTCS-----------------HLEVSSLCEEHRMDGCF--------CPEGAQADLPKTV 348
              TCS                 H + S +  +   D  F        C      +  K V
Sbjct: 1081 PGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENCLKAV 1140

Query: 349  VLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLA 408
             L  D     +  ++DG V LN +   LP   A+ ++F PSS+ I+V   +G++L VQL 
Sbjct: 1141 TLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLV 1200

Query: 409  PVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKL 468
            P+MQ+FV LD A QGQ+ GLCGNFN  + DDF   SG+VEATGA FANTWKAQ++C +  
Sbjct: 1201 PLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANAR 1260

Query: 469  DWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDC 528
            +  +DPCSL++E+ NYA HWCS L    + F RCHS ++P  ++  C +DTCNC+ +EDC
Sbjct: 1261 NSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDC 1320

Query: 529  LCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSH 588
            LCAALSSY  AC AKGV L  WR+ VC K + +CP SQ + Y +  CQ TCR LSEAD  
Sbjct: 1321 LCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVT 1380

Query: 589  CLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRL 648
            C   F PVDGC CP  TFL++ G CVP  +C CY  G  L  G+VV  +   C C  G+L
Sbjct: 1381 CSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKL 1440

Query: 649  HCRQIRL-IGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGL 707
             C    L     C AP +++DCSN +A         SC TL  G + T CVSGCVCP GL
Sbjct: 1441 SCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGL 1500

Query: 708  MDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSG 767
            + DG GGC+ E++CPCVHN   Y  G  I+VDCNTCTC+  RW C+  +C GTC  YG G
Sbjct: 1501 VSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDG 1560

Query: 768  HYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMG- 826
            H+ITFDG  Y F+G C Y+  QDYCG N++ G+F I+TEN+PCGTTG TCSKAIK+F+  
Sbjct: 1561 HFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEV 1620

Query: 827  RT---------------------------------ELKLEDKHRVVIQRDEGHHVAYTTR 853
            RT                                 EL L++     + R  G    Y  R
Sbjct: 1621 RTAPAVSTPDPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIR 1680

Query: 854  EVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVS 913
             +G +LV+E+  G+ V WD++T+VFI+L   YKG VCGLCGNFD  + NDF TR   VV 
Sbjct: 1681 YMGIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVG 1739

Query: 914  SELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFY 973
              L+FGNSWK +P+CPD     +PC+ NP R+SWA+KQCSIL    F+ C S+VD   +Y
Sbjct: 1740 DALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYY 1799

Query: 974  EACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEW 1033
            EACV+D+C+CD+GGDCECFC+AVA+YAQ C   G CV WRTPD CP+FCD+YNP   CEW
Sbjct: 1800 EACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEW 1859

Query: 1034 HYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVE 1093
            HY+PCG    +TCR  +G H  + +  LEGCYP+CP  +P + ED  KCV   +CGCY +
Sbjct: 1860 HYQPCGAPCLKTCRNPSG-HCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVA--QCGCYDK 1916

Query: 1094 D-THYPPGASVPTEETCKSCVCTNS--------SQVVCRPE------EGKILNQTQDGAF 1138
            D  +Y  GA VPT E C+SC CT S            C  E      +  I N T     
Sbjct: 1917 DGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGA 1976

Query: 1139 CYWEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTT--TTTPTSSTVL 1196
            C   ICG NGT+ +    C  T               TTP TFTT     +TT  +  V 
Sbjct: 1977 CLIAICGSNGTIIRKAVACPGTP-------------ATTPFTFTTAWVPHSTTSPALPVS 2023

Query: 1197 STTPKLCCLWSDWINEDHPSSGSDDGDRETFDG-------VCGAPEDIECRSVKDPHLSL 1249
            +   +  C WS W N   P  G   GD ETF+        VC    DIECR+ + P + L
Sbjct: 2024 TVCVREVCRWSSWYNGHRPEPGLGGGDFETFENLRQRGYQVCPVLADIECRAAQLPDMPL 2083

Query: 1250 EQLGQKVQLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECV---------TQP 1300
            E+LGQ+V   CD   GL+C N  Q P        C +YE+ V CCE V         T P
Sbjct: 2084 EELGQQVD--CDRMRGLMCANSQQSP------PLCHDYELRVLCCEYVPCGPSPAPGTSP 2135

Query: 1301 TTMTTTTTENPTPTPITTT----TTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQT 1356
                + +TE   PTP  TT    TT+  TP+  ST + T    +++  VT TP+  GT T
Sbjct: 2136 QPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVTVTPSAPGTTT 2195



 Score =  811 bits (2094), Expect = 0.0
 Identities = 549/1600 (34%), Positives = 756/1600 (47%), Gaps = 207/1600 (12%)

Query: 1160 TTRPSTLTTFTTITLPTTPT-TFTTTTTTTTPTSS---TVLSTTPKLCCLWSDWINEDHP 1215
            TT P   T  +  T   TP+ T T+T   ++PTS+   TV++T  +  C WS+W++  +P
Sbjct: 4557 TTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYP 4616

Query: 1216 SSGSDDGDRETFDG-------VCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLIC 1268
              G   GD +T+         VC  P  +ECR+   P + L +LGQ V+  C +  GL+C
Sbjct: 4617 MPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVE--CSLDFGLVC 4674

Query: 1269 KNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTP--------ITTTT 1320
            +N +Q    V     C NYEI V CC     P+T  T++T  P+ TP        +TTT 
Sbjct: 4675 RNREQ----VGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTA 4730

Query: 1321 TVTP----TPTPTSTQSTTPTPI------------------------------------- 1339
            T T     T TP+ST  T P P                                      
Sbjct: 4731 TTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATK 4790

Query: 1340 TTTTTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPT------TTPITTT 1388
            +T T+VTP P+ T   T      TTTP+ T +T+ P+ TP  T T T      TT   T+
Sbjct: 4791 STATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATS 4850

Query: 1389 TTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQA 1448
            +T TP+ TP  T   T      TTT    PT T + TP TT I T  T T T        
Sbjct: 4851 STSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTAT-------- 4902

Query: 1449 PTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTPTAITTTTT 1505
               T  +T ST TP+ TP GT    T P TT T   P   T T + TQ    T   +TT 
Sbjct: 4903 ---TTASTGSTATPSSTP-GTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTA 4958

Query: 1506 VTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQT-- 1563
             TPT T +   TP+S+P   T T  P    T T     TP +T+ T  P+ +   T T  
Sbjct: 4959 TTPTVT-SSKATPSSSP--GTATALPALRSTAT-----TPTATSFTAIPSSSLGTTWTRL 5010

Query: 1564 -PTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTT------MTPTPTPTSTKSTTVTPIT 1616
              TTTP  T +T TP+ TP    T T +  T TTT       TP+ TP  T  TT  P T
Sbjct: 5011 SQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTP-GTAHTTKVPTT 5069

Query: 1617 TTTTVTATPTP---TGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSN 1673
            TTT  TATP+    T    PT  P+ST +T+  + TP T      THTST      T + 
Sbjct: 5070 TTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPET------THTSTVLTTTATMTR 5123

Query: 1674 PPPESSTPQTSRSTSSPLTESTTLLSTL-----------PPAIEMTSTAPPSTPTAPTTT 1722
                ++TP ++  T+  LTE TT  +T             P      T P +  T    T
Sbjct: 5124 ATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPT 5183

Query: 1723 SGGHTLSPPPSTTTSPPGTPTRGT--TTGSSSAPTPSTVQTTTTSAWTPTPTP---LSTP 1777
                T S    T  +P    T  T  T  +S+ P+ STV TT T A  P+  P   +ST 
Sbjct: 5184 GSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTV 5243

Query: 1778 SIIRTTGLRP--YPS---SVLICCVLNDTYYAPGEEVYNGTYGDTCYF-VNCSLSCTLEF 1831
            S    T LRP  +PS   S    C     +++PGE +YN T    C+F   C+  C ++ 
Sbjct: 5244 SSSVLTTLRPTGFPSSHFSTPCFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQHCDIDR 5303

Query: 1832 YNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCDCF 1891
            +  +CP++P P  +   S+P+P+               P C +  P RQ NETW L +C 
Sbjct: 5304 FQGACPTSPPPVSSAPLSSPSPA---------------PGCDNAIPLRQVNETWTLENCT 5348

Query: 1892 MATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDP-DGCCWHWECDCYCTG------- 1943
            +A C  +N   +V ++ +P    TC N   P++V DP   C +H+EC+C C G       
Sbjct: 5349 VARCVGDN--RVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGITPG 5406

Query: 1944 ------WGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVS--- 1994
                  WG  HY TFDG  Y+++GNCTYVL+ EI     N  +Y+DN++C  +   +   
Sbjct: 5407 AGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAA 5466

Query: 1995 --CPRTLIVRHETQEVLIKTVHMMPMQVQ--VQVNRQAVALPYKKYGLEVYQSGINYV-V 2049
              CPR L + +++ ++++ TV M+  + +  +  ++  V+  + K G+ V   G   + V
Sbjct: 5467 ARCPRALSIHYKSMDIVL-TVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRV 5525

Query: 2050 DIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAAD 2109
            DIP LGV V++NG  F  RLPY  F NNT+GQCGTCTN   DDC+   G   ++C+  A 
Sbjct: 5526 DIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAK 5585

Query: 2110 QWLVNDPSKPHC--PHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHAL 2167
             WLV D  K  C  P  +  T  PA  V      TP   C P PLC L+   +FA+CH L
Sbjct: 5586 TWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTP---CPPQPLCDLMLSQVFAECHNL 5642

Query: 2168 VPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHRE 2227
            VPP  +++AC+ D C      + C SL+AYA LC  + +C DWR  T G C + CP  + 
Sbjct: 5643 VPPGPFFNACISDHC-RGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKV 5701

Query: 2228 YQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREF 2287
            Y+ CGP +  TC S +       + EGCFCPE  + +     +CV+ C CVGPD  P+  
Sbjct: 5702 YKPCGPIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFP 5761

Query: 2288 GEHFEFDCKNCVCLEGGSGIICQPKRC-SQKPVTHCVEDGTYLATEVNPADTCCNITVCK 2346
            GE +  +C++CVC EG   + C+P  C +Q     C   G    T     + CC  TVC 
Sbjct: 5762 GERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCV 5821

Query: 2347 CNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSS-KCQ 2405
            CNT+ C +   VCP G E       G CCP + C  + +C +    Y  G+    +  C 
Sbjct: 5822 CNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQ-LCSYNGTFYGVGATFPGALPCH 5880

Query: 2406 DCVCTDKVDNNTLLNVIACTHVPC-NTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQH 2464
             C C   +  +T    + C    C NT+C  GFE     G+CC +C QT C+   PD Q 
Sbjct: 5881 MCTC---LSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACL--TPDGQP 5935

Query: 2465 VILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIPGSITFMPNGCCKT 2524
            V L    + +   +NCT + C       + +    +CP  D S C  GS+     GCC +
Sbjct: 5936 VQLNE-TWVNSHVDNCTVYLCEAEGGVHLLTPQPASCP--DVSSC-RGSL--RKTGCCYS 5989

Query: 2525 CTPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYSAKAQALDHSCSCCKE 2584
            C   +     C     TT + + GC   V +  C GSC     YSA+AQA+ H C+CC+E
Sbjct: 5990 CEEDS-----CQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQE 6044

Query: 2585 EKTSQREVVLSCPNGGSLTHTYTHIESCQCQDTVCGLPTG 2624
             +  +  V L CPNG ++ HTYTH     C     GL  G
Sbjct: 6045 RRVHEETVPLHCPNGSAILHTYTHAVQVLCGLLAWGLQAG 6084



 Score =  315 bits (807), Expect = 4e-85
 Identities = 205/562 (36%), Positives = 283/562 (50%), Gaps = 114/562 (20%)

Query: 28  RTRNHGHN--VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQA 85
           R  N  HN  VCSTWG+FHYKTFDGDVFRFPGLC+Y F+  C  +Y++F + L+R   Q 
Sbjct: 70  RASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRS--QE 127

Query: 86  EAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTL 145
            A   +  +L+ +    I LT+   ++NG  V  P    G+LI++S +YTKV +R GL L
Sbjct: 128 SAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGLVL 187

Query: 146 MWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVV 205
           MWN +D+L+LELDTK+ N TCGLCGD+NG+   SE LS     +P+EFGN+QK++ P   
Sbjct: 188 MWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDDPTEQ 247

Query: 206 CEDPEEEVAPASCSEHRAECERLLTAEAFADC--------------QDLV---------- 241
           C+DP  E  P +CS     CE LL  + F+ C              QDL           
Sbjct: 248 CQDPVPE-PPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSC 306

Query: 242 ---PLEPYLRAC------------------------QQDRCRCPGGDTCVCSTVAEFSRQ 274
               L  Y R C                        Q   CR P  DTC   +  E SR 
Sbjct: 307 VCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTC---SNQEHSRA 363

Query: 275 CSH---AG------------GRPGNWRTAT-------SAVSPGASK-------TCPGNLV 305
           C     AG            G+ G    +        +A +PGA+        TC G   
Sbjct: 364 CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRW 423

Query: 306 YLESGSPCMDTCSHLEVSSLC----EEHRMDG-CF------CPEGAQADLP--------- 345
             +   PC  TCS L  +       +++ + G C       C   A   L          
Sbjct: 424 SCQE-VPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTD 482

Query: 346 -----KTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIG 400
                K+V L  D  + VVV K+ G V LN++   LP   A+ ++FRPS++ I+   ++G
Sbjct: 483 SETCLKSVTLSLDGAQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLG 542

Query: 401 VRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKA 460
           ++L +QL P MQLF+ L    +GQ  GLCGNFN ++ DDF+T SG+VEAT A F NT+K 
Sbjct: 543 LQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT 602

Query: 461 QSSCHDKLDWLDDPCSLNIESA 482
           Q++C +  +  +DPCSL++E+A
Sbjct: 603 QAACPNIRNSFEDPCSLSVENA 624



 Score =  306 bits (785), Expect = 1e-82
 Identities = 247/715 (34%), Positives = 332/715 (46%), Gaps = 111/715 (15%)

Query: 1160 TTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLC---CLWSDWINEDHPS 1216
            TT   T  T  T    T   T T+T   ++PTS+ + +     C   C WS+W++  +P 
Sbjct: 3411 TTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPM 3470

Query: 1217 SGSDDGDRETFDG-------VCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICK 1269
             G   GD +T+         VC  P  +ECR+   P + L +LGQ V+  C +  GL+C+
Sbjct: 3471 PGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVE--CSLDFGLVCR 3528

Query: 1270 NEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTP------------IT 1317
            N +Q    V     C NYEI V CC     P+T  T++T  P+ TP             T
Sbjct: 3529 NREQ----VGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAAT 3584

Query: 1318 TTTTVTPTPTPTSTQSTTPTP-ITTTTTVTPTPTPT------GTQTPTTTPI-------T 1363
            TT T   T  P+ST  T P P + T+T  TPT T +        +T TT P+       +
Sbjct: 3585 TTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKS 3644

Query: 1364 TTTTVTPTPT----PTGT-QTPTTTPITTTTTVTPTPTPTGTQT---------------- 1402
            T T+ TP P+     TGT    TTTP+ T +T+ P+ TP  T T                
Sbjct: 3645 TATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSS 3704

Query: 1403 ---PTSTPITT------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTA 1453
               P+STP TT      TT  T T     T TP++TP TT     P+ T T T  PT + 
Sbjct: 3705 MSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVT-VPTGST 3763

Query: 1454 ITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPT 1513
             T +ST     T     +  TTP   ++  TP+ +P GT T  P   +T TT T T    
Sbjct: 3764 ATASSTRATAGTLKVLTSTATTPTVISSRATPSSSP-GTATALPALRSTATTPTATSV-- 3820

Query: 1514 GTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTT 1573
             T  P+S+  T  T ++ T TPT T + T TP ST  TV    T T   T TTT   T +
Sbjct: 3821 -TAIPSSSLGTAWTRLSQTTTPTATMS-TATPSSTPETV---HTSTVLTTTTTTTRATGS 3875

Query: 1574 TVTPTPTPTGTQTPTTVLITTTTTMTPTP--------TPTSTKSTTVTPITTTTTVTATP 1625
              TP+ TP GT   T V  TTTT  T TP        TP    STT TP T  +TVT + 
Sbjct: 3876 VATPSSTP-GTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSS 3934

Query: 1626 TPTGTQTPTMIPISTTTTVT---PTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQ 1682
             P  T T T++  +TTT  T    TP+ +T ++G  THT   P    TT       S+P 
Sbjct: 3935 IPGTTHTATVLTTTTTTVATGSMATPSSSTQTSG-TTHTPPVPNTTATTHGRSLPPSSPH 3993

Query: 1683 TSRST----------SSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPP 1732
            T R+           ++ +TE +T+ S  P A   TST   STP   +      T   PP
Sbjct: 3994 TVRTAWTSATSGILGTTHITEPSTVTSHTPAA--TTSTTQHSTPALSSPHPSSRTTESPP 4051

Query: 1733 STTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRP 1787
            S  T+ PG  TRGT+  +++A TPS  +T+T    +PT  P++T   + TTG  P
Sbjct: 4052 SPGTTTPG-HTRGTSRTTATA-TPSKTRTSTLLPSSPTSAPITT---VVTTGCEP 4101



 Score =  273 bits (697), Expect = 2e-72
 Identities = 276/878 (31%), Positives = 373/878 (42%), Gaps = 159/878 (18%)

Query: 1099 PGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNICS 1158
            PG +  T  T  +   T  S    RP +   L  T            P GT         
Sbjct: 2379 PGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMAT----SRARPTGTASTASKEPL 2434

Query: 1159 ITTRPSTLTTFTTITLPTTPTTFTTTTT---TTTPTSSTVLSTTPKLCCLWSDWINEDHP 1215
             T+   TLT+  + +   T T  T TT    T T TS       PK  C W++W + D P
Sbjct: 2435 TTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPK--CEWTEWFDVDFP 2492

Query: 1216 SSGSDDGDRETFDGV-------CGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLIC 1268
            +SG   GD ETF+ +       C AP+ IECR+   P +S++Q+GQ   L C +  GL C
Sbjct: 2493 TSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQV--LTCSLETGLTC 2550

Query: 1269 KNEDQKPGGVIPMAFCLNYEINVQCCECVTQ-PTTMTTTTTENPTPTPITT------TTT 1321
            KNEDQ   G   M  C NY + V CC+  +  P+T  T++T  P+ TP TT      TTT
Sbjct: 2551 KNEDQT--GRFNM--CFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTT 2606

Query: 1322 VTPTP------TPTSTQSTTPTPITTTTTVTPTPTPTGTQ-TPTTTPITTT-------TT 1367
             T T       TPTST  T P P   TTT T TPT T ++ TP+++P T T       T 
Sbjct: 2607 ATTTASTGSTATPTSTLRTAPPPKVLTTTAT-TPTVTSSKATPSSSPGTATALPALRSTA 2665

Query: 1368 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTSTPIT--TTTTVTPTPTPTG 1422
             TPT T   T  P+++  TT T ++ T TPT T    TP+STP T  T+T +T T T TG
Sbjct: 2666 TTPTATSV-TPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTG 2724

Query: 1423 ----TQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPIT 1478
                  TP++TP T  TT  PT T TG  A TP++   T+   P    T     TTTP T
Sbjct: 2725 ATGSVATPSSTPGTAHTTKVPTTTTTGFTA-TPSSSPGTALTPPVWIST-----TTTPTT 2778

Query: 1479 TTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGT 1538
              +TVTP+  P GT T T T +TTTTT   T +     TP+S+  T+ TT TP       
Sbjct: 2779 RGSTVTPSSIP-GT-THTATVLTTTTTTVATGS---MATPSSSTQTSGTTHTP------- 2826

Query: 1539 QTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTM 1598
              P P  ++TT   +  P+   T     T  T+    T   T   T T  T+  TT TT 
Sbjct: 2827 --PVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQ 2884

Query: 1599 TPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPP 1658
              TP  +S       P  ++ T  + P+P GT TP     ++ TT T TP+ T  ST  P
Sbjct: 2885 HSTPALSS-------PHPSSRTTESPPSP-GTTTPGHTTATSRTTATATPSKTRTSTLLP 2936

Query: 1659 THTSTAPIAELTTSNPPPES--------STPQTSRS-----TSSPLTESTTLLSTLPPAI 1705
            +  ++API  + T    P+         S P    S     T S +  +   +   P  +
Sbjct: 2937 SSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGL 2996

Query: 1706 EMTSTAPPSTPTAPT----------------------------------TTSGGHTLSPP 1731
            E  + A P  P                                        + GH  S P
Sbjct: 2997 ECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTP 3056

Query: 1732 PSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSS 1791
             +++T+ P      +T G++   T  T   TTT +   T TP STP    TT +   PS+
Sbjct: 3057 ATSSTAMP-----SSTPGTTWILTELTTTATTTESTGSTATPSSTPG---TTWILTEPST 3108

Query: 1792 VLICCV-LNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKST 1850
                 V    T  A   +   GT        + S + T            +PT T SK+T
Sbjct: 3109 TATVTVPTGSTATASSTQATAGT-------PHVSTTAT------------TPTVTSSKAT 3149

Query: 1851 P--TPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWW 1886
            P  +P   ++ P+  +  T P        P     T W
Sbjct: 3150 PFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTW 3187



 Score =  272 bits (696), Expect = 3e-72
 Identities = 261/863 (30%), Positives = 360/863 (41%), Gaps = 183/863 (21%)

Query: 1160 TTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSS---TVLSTTPKLCCLWSDWINEDHPS 1216
            TT   T  T  T    T   T T+T   ++PTS+   TV++T  +  C WS+W++  +P 
Sbjct: 4056 TTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPM 4115

Query: 1217 SGSDDGDRETFDG-------VCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICK 1269
             G   GD +T+         VC  P  +ECR+   P + L +LGQ V+  C +  GL+C+
Sbjct: 4116 PGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVE--CSLDFGLVCR 4173

Query: 1270 NEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPT 1329
            N +Q    V     C NYEI V CC     P+T  T++T  P+ TP TT      T T T
Sbjct: 4174 NREQ----VGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTAT 4229

Query: 1330 STQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPIT 1386
            +T+S       T +T TP+ TP GT    T P TT T   P   T T + TQ    TP  
Sbjct: 4230 TTES-------TGSTATPSSTP-GTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHV 4281

Query: 1387 TTTTVTPTPTPTGTQTPTSTPITTT-------TTVTPTPTPTGTQTPTTTPITTTTTVTP 1439
            +TT  TPT T +   TP S+P T T       T  TPT T + T  P+++  TT T ++ 
Sbjct: 4282 STTATTPTVT-SSKATPFSSPGTATALPALRSTATTPTAT-SFTAIPSSSLGTTWTRLSQ 4339

Query: 1440 TPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTT------VTPTPTP-TGT 1492
            T TPT T           ST TP+ TP    T T    T TTT       TP+ TP T  
Sbjct: 4340 TTTPTATM----------STATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAH 4389

Query: 1493 QTPTPTAITTTTTVTPTPTPTGTQTP------TSTPITTTTTVTPTPTPTGTQTPTPTPI 1546
             T  PT  TT  TVTP+ +P   +TP      T+TP T+ +TVTP+  P  T TPT    
Sbjct: 4390 TTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTT 4449

Query: 1547 STTTTVT---PTPTPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTTVLITTTT-T 1597
            +TTT  T    TP+ + TQT  TT     P TT TT   + +P+   T  T   + T+ T
Sbjct: 4450 TTTTVATGSMATPS-SSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGT 4508

Query: 1598 MTPTPTPTSTKSTTVTPITTTTT----------------VTATPTPTGTQTPTMIPISTT 1641
            +  T     +  T+ TP  TT T                 T +P   GT TP     ++ 
Sbjct: 4509 LGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSR 4568

Query: 1642 TTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPES--------STPQTSRS-----TS 1688
            TT T TP+ T  ST  P+  ++API  + T+   P+         S P    S     T 
Sbjct: 4569 TTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTY 4628

Query: 1689 SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPT---------------------------- 1720
            S +  +   +   P  +E  + A P  P                                
Sbjct: 4629 SNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFN 4688

Query: 1721 ------TTSGGHTLSPPPSTTT----SPPGTP---TRGTTTGSSSAPTPSTVQTTTTSAW 1767
                    + GH  S P +++T    S PGT    T  TTT +++A T ST   ++T   
Sbjct: 4689 YEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGT 4748

Query: 1768 TPTPTPLSTPSIIRT------------------------------TGLRPYPSSVL---- 1793
             P P  L++P+   T                              T + P PSS L    
Sbjct: 4749 APPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTG 4808

Query: 1794 ICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTP--------- 1844
                   T  A    ++  +  +T +      +        S  STPS TP         
Sbjct: 4809 TLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTEL 4868

Query: 1845 TPSKSTPTPSKPSSTPSKPTPGT 1867
            T + +T   + P++TPS  TPGT
Sbjct: 4869 TTAATTTAATGPTATPSS-TPGT 4890



 Score =  266 bits (680), Expect = 2e-70
 Identities = 250/782 (31%), Positives = 329/782 (42%), Gaps = 156/782 (19%)

Query: 1160 TTRPSTLTTFTTITLPTTPT-TFTTTTTTTTPTSSTVLSTTPKLC---CLWSDWINEDHP 1215
            TT P   T  +  T   TP+ T T+T   ++PTS+ + +     C   C WS+W++  +P
Sbjct: 2908 TTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYP 2967

Query: 1216 SSGSDDGDRETFDG-------VCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLIC 1268
              G   GD +T+         VC  P  +ECR+   P + L +LGQ V+  C +  GL+C
Sbjct: 2968 MPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVE--CSLDFGLVC 3025

Query: 1269 KNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTP 1328
            +N +Q    V     C NYEI V CC     P+T  T++T  P+ TP TT      T T 
Sbjct: 3026 RNREQ----VGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTA 3081

Query: 1329 TSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1388
            T+T+S       T +T TP+ TP GT    T P TT T   PT +               
Sbjct: 3082 TTTES-------TGSTATPSSTP-GTTWILTEPSTTATVTVPTGS--------------- 3118

Query: 1389 TTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQA 1448
                 T T + TQ    TP  +TT  TPT T +       TP ++  T T  P    T A
Sbjct: 3119 -----TATASSTQATAGTPHVSTTATTPTVTSS-----KATPFSSPGTATALPALRST-A 3167

Query: 1449 PTPTAITTTSTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVT 1507
             TPTA + T+  + +   T T+ + TTTP  T +T TP+ TP    T T      TTT T
Sbjct: 3168 TTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTST----VLTTTAT 3223

Query: 1508 PTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTT 1567
             T       TP+STP T  TT   T T TG    T TP S+  T    P    T   TTT
Sbjct: 3224 TTGATGSVATPSSTPGTAHTTKVLTTTTTGF---TATPSSSPGTARTLPVWIST---TTT 3277

Query: 1568 PITTTTTVTPTPTPTGTQTPTTVLITTTTTMT---PTP-TPTSTKSTTVTPITTTTTVTA 1623
            P T  +TVTP+  P  T TPT +  TTTT  T    TP + T T  TT TP    TT T 
Sbjct: 3278 PTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTAT- 3336

Query: 1624 TPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQT 1683
                  T   ++ P S  T  T   + T+G+ G             TT    P + T  T
Sbjct: 3337 ------THGRSLSPSSPHTVRTAWTSATSGTLG-------------TTHITEPSTGTSHT 3377

Query: 1684 SRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPT 1743
              +T+     ST  LS+  P+   T+ +PPS    P TT+ GHT +   +T T+ P + T
Sbjct: 3378 PAATTGTTQHSTPALSSPHPS-SRTTESPPS----PGTTTPGHTRATSRTTATATP-SKT 3431

Query: 1744 RGTTTGSSSAPTPSTVQTTTT------SAWT-------PTPTP----LSTPSIIRTTGLR 1786
            R T+T   S+PT + + T  T       AW+       P P P      T S IR  G  
Sbjct: 3432 R-TSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGA 3490

Query: 1787 PYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYN------------- 1833
                 + + C        P  E+           V CSL   L   N             
Sbjct: 3491 VCEQPLGLECRAQAQPGVPLRELGQ--------VVECSLDFGLVCRNREQVGKFKMCFNY 3542

Query: 1834 ---------WSCPSTP--SPTPTPSK--------------STPTPSKPSSTPSKPTPGTK 1868
                       CPSTP  S T TPS               +T T +  S+     TPGT 
Sbjct: 3543 EIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTA 3602

Query: 1869 PP 1870
            PP
Sbjct: 3603 PP 3604



 Score =  211 bits (536), Expect = 1e-53
 Identities = 257/868 (29%), Positives = 351/868 (40%), Gaps = 159/868 (18%)

Query: 1110 KSCVCTNSSQV--VCRPEEGKILNQTQDGAFCYWEICGPN---GTVEKHFNICSITTRPS 1164
            +  +C NS Q   +C   E ++L        C +  CGP+   GT  +     S +T P+
Sbjct: 2096 RGLMCANSQQSPPLCHDYELRVL-------CCEYVPCGPSPAPGTSPQPS--LSASTEPA 2146

Query: 1165 TLT-TFTTITLPTT-----PTTFTTTTTTTTPTSSTVLSTTPKL-----C---CLWSDWI 1210
              T T TT T  TT         T   T+ T +SS  ++ TP       C   C W++W 
Sbjct: 2147 VPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVTVTPSAPGTTTCQPRCQWTEWF 2206

Query: 1211 NEDHPSSGSDDGDRETFDGV-------CGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVS 1263
            +ED+P S    GD E++D +       C  P+DIEC++   P+ +L Q+GQKV   CDV 
Sbjct: 2207 DEDYPKSEQLGGDVESYDKIRAAGGHLCQQPKDIECQAESFPNWTLAQVGQKVH--CDVH 2264

Query: 1264 VGLICKNEDQKPGGVIPMAFCLNYEINVQCCE---CVTQPTTMTTTTTENPTPTPITTTT 1320
             GL+C+N +Q+  GV  M  C NY I V CC    C  + TT   TT      T  TTT 
Sbjct: 2265 FGLVCRNWEQE--GVFKM--CYNYRIRVLCCSDDHCRGRATTPPPTTELETATT--TTTQ 2318

Query: 1321 TVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1380
             +  TP PTS+   T  P  +TT V PT +   T    T+ + T TT  PT TP G+  P
Sbjct: 2319 ALFSTPQPTSSPGLTRAPPASTTAV-PTLSEGLTSPRYTSTLGTATTGGPT-TPAGSTEP 2376

Query: 1381 TTTPITTTTTVTPTPTP-----TGTQTPTSTP-ITTTTTVTPTPTPTGTQTPTTTPITTT 1434
            T   + T+T  T +  P      GT  P+  P +  TT  T    PTGT + T +    T
Sbjct: 2377 TVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGTAS-TASKEPLT 2435

Query: 1435 TTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 1494
            T++ PT T         + ++T+   T TP    T +P T   T+  T    P    T+ 
Sbjct: 2436 TSLAPTLT---------SELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTE- 2485

Query: 1495 PTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTP 1554
                         PT    G    T   I             G     P  I       P
Sbjct: 2486 -------WFDVDFPTSGVAGGDMETFENIRAA---------GGKMCWAPKSIECRAENYP 2529

Query: 1555 TPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTVLITTTTTMTPTPTPTSTKS 1609
              +        T  + T  T       TG           VL     +  P+   TS+ +
Sbjct: 2530 EVSIDQVGQVLTCSLETGLT-CKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTA 2588

Query: 1610 T-TVTPITT------TTTVTATPTPTGTQTPTMI-------PISTTTTVTPTPTPT--TG 1653
            T + TP TT      TTT T T +   T TPT          + TTT  TPT T +  T 
Sbjct: 2589 TPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATP 2648

Query: 1654 STGPPTHT------STAPIAELTTSNPPPESS------------TPQTSRSTSSP-LTES 1694
            S+ P T T      STA     T+  P P SS            TP  + ST++P  T  
Sbjct: 2649 SSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE 2708

Query: 1695 TTLLSTLPPAIEMTSTA------PPSTP------TAPTTTSGGHTLSP--PPSTTTSPP- 1739
            T   ST+  A   T+ A      P STP        PTTT+ G T +P   P T  +PP 
Sbjct: 2709 TAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPV 2768

Query: 1740 --GTPTRGTTTGSSSAPT--PSTVQ-------TTTTSAWTPTPTPLSTPSIIRTTGLRPY 1788
               T T  TT GS+  P+  P T         TTTT A     TP S+     TT   P 
Sbjct: 2769 WISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPV 2828

Query: 1789 PSSVLICCVLN------DTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSP 1842
            P+++      +       T         +G  G T    + +   T+  +  +  +  + 
Sbjct: 2829 PNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTT----HITEPSTVTSHTLAATTGTTQ 2884

Query: 1843 TPTPSKSTPTPSKPSSTPSKPTPGTKPP 1870
              TP+ S+P PS   +T S P+PGT  P
Sbjct: 2885 HSTPALSSPHPSS-RTTESPPSPGTTTP 2911



 Score =  194 bits (494), Expect = 7e-49
 Identities = 182/540 (33%), Positives = 234/540 (43%), Gaps = 78/540 (14%)

Query: 1371 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTP 1430
            TP  + T TP++TP TT      T   T T T  ST I ++T  T  P    T T  TTP
Sbjct: 3557 TPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTST-ATTP 3615

Query: 1431 ITTTTTVTPTPTP-TGTQAPTPTAITTTSTVTP-TPTP------TGT-QTPTTTPITTTT 1481
              T++  T + +P T T  P  T+  T ST T  TP P      TGT    TTTP+ T +
Sbjct: 3616 TATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMS 3675

Query: 1482 TVTPTPTPTGTQTPTPTAITTTTT------VTPTPTPTGTQTPTSTPITTTTTVTPTPTP 1535
            T+ P+ TP  T T T      TTT       TP+ TP  T   T      TTT    PT 
Sbjct: 3676 TIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTA 3735

Query: 1536 TGTQTPTPTPI----STTTTVTPTPTPTGTQTPT--------------TTPITTTTTVTP 1577
            T + TP  T I    STT TVT     T T + T              TTP   ++  TP
Sbjct: 3736 TPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATP 3795

Query: 1578 TPTPTGTQTPTTVLITTTTTMTPTPT---PTSTKSTTVTPITTTTTVTAT-PTPTGTQTP 1633
            + +P GT T    L +T TT T T     P+S+  T  T ++ TTT TAT  T T + TP
Sbjct: 3796 SSSP-GTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTP 3854

Query: 1634 TMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTE 1693
              +  ST  T T T T  TGS   P                   SSTP T+ +T  P T 
Sbjct: 3855 ETVHTSTVLTTTTTTTRATGSVATP-------------------SSTPGTAHTTKVPTTT 3895

Query: 1694 STTLLSTLPPAIEMTSTAPP---STPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS 1750
            +T   +T P +   T+  PP   ST T PTT     T S  P TT +     T  TT  +
Sbjct: 3896 TTGFTAT-PSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVAT 3954

Query: 1751 SSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVY 1810
             S  TPS+  +T TS  T TP     P+   TT  R  P S         T         
Sbjct: 3955 GSMATPSS--STQTSGTTHTP---PVPNTTATTHGRSLPPS------SPHTVRTAWTSAT 4003

Query: 1811 NGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPP 1870
            +G  G T    + +   T+  +  +  ++ +   TP+ S+P PS   +T S P+PGT  P
Sbjct: 4004 SGILGTT----HITEPSTVTSHTPAATTSTTQHSTPALSSPHPSS-RTTESPPSPGTTTP 4058



 Score =  188 bits (477), Expect = 7e-47
 Identities = 205/676 (30%), Positives = 264/676 (39%), Gaps = 139/676 (20%)

Query: 1298 TQPTTMTTTTTENPTP------TPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTP 1351
            T PTT  +T T +  P      T +TTTTT   T +  +  S+T T  TT T   P  T 
Sbjct: 3921 TTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTA 3980

Query: 1352 T--GTQTPTTTPIT----------------------TTTTVTPTPTPTGTQ--TPTTTPI 1385
            T  G   P ++P T                      T T+ TP  T + TQ  TP  +  
Sbjct: 3981 TTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSP 4040

Query: 1386 TTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQT-----PTTTPITTTTTVT-- 1438
              ++  T +P   GT TP  T  T+ TT T TP+ T T T     PT+ PITT  T    
Sbjct: 4041 HPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCE 4100

Query: 1439 -------------PTPTPTGTQAPTPTAITTTSTVT---PTPTPTGTQTPTTTPITTTTT 1482
                         P P P+G    T + I          P       Q     P+     
Sbjct: 4101 PQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQ 4160

Query: 1483 VTPTPTPTGTQTPTPTAITTTTTV---------------TPTPTPTGTQTPTSTPITT-- 1525
            V       G        +                       TP  + T TP+STP TT  
Sbjct: 4161 VVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWI 4220

Query: 1526 ----TTTVTPTPTPTGTQTPTPTP--------ISTTTTVT----PTPTPTGTQTPTTTPI 1569
                TTT T T +   T TP+ TP         STT TVT     T T + TQ    TP 
Sbjct: 4221 LTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPH 4280

Query: 1570 TTTTTVTPTPTPT--------GTQTPTTVLITTTTTMTP---TPTPTSTKSTTVTPITTT 1618
             +TT  TPT T +        GT T    L +T TT T    T  P+S+  TT T ++ T
Sbjct: 4281 VSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQT 4340

Query: 1619 TTVTAT-PTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPE 1677
            TT TAT  T T + TP     ST  T T T T  TGS   P                   
Sbjct: 4341 TTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATP------------------- 4381

Query: 1678 SSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPP---STPTAPTTTSGGHTLSPPPST 1734
            SSTP T+ +T  P T +TT  +  P +   T+  PP   ST T PTT+    T S  P T
Sbjct: 4382 SSTPGTAHTTKVP-TTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGT 4440

Query: 1735 TTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLI 1794
            T +P    T  TT  + S  TPS+   T+ +  TP P P +T +   T G    PSS   
Sbjct: 4441 THTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTP-PVPNTTAT---THGRSLSPSS--- 4493

Query: 1795 CCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPS 1854
                  T         +GT G T    + +   T   +  +  +  +   TP+ S+P PS
Sbjct: 4494 ----PHTVRTAWTSATSGTLGTT----HITEPSTGTSHTPAATTGTTQHSTPALSSPHPS 4545

Query: 1855 KPSSTPSKPTPGTKPP 1870
               +T S P+PGT  P
Sbjct: 4546 S-RTTESPPSPGTTTP 4560



 Score =  178 bits (451), Expect = 7e-44
 Identities = 192/646 (29%), Positives = 262/646 (40%), Gaps = 86/646 (13%)

Query: 1103 VPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTR 1162
            VP  E  +   C+    +VCR       N+ Q G F   ++C      E     C+    
Sbjct: 3508 VPLRELGQVVECSLDFGLVCR-------NREQVGKF---KMCF---NYEIRVFCCNYGHC 3554

Query: 1163 PSTLTTFTTITLPTTP------TTFTTTTTTTTPTSSTVL-STTPKLCCLWSDWINEDHP 1215
            PST  T +T T  +TP      T  TT  TTT  T ST + S+TP               
Sbjct: 3555 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTP--------------- 3599

Query: 1216 SSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQKP 1275
                  G       +          S K    S  +    + ++   +      +    P
Sbjct: 3600 ------GTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIP 3653

Query: 1276 GGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPT--PTPITTTTTVTPTPTPTSTQS 1333
               +     L  +         T   + T  TT   T   T  TTT   +   TP+ST  
Sbjct: 3654 SFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPG 3713

Query: 1334 TTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1393
            TT      TT  T T     T TP++TP TT     P+ T T      T P  +T T + 
Sbjct: 3714 TTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTAT-----VTVPTGSTATASS 3768

Query: 1394 TPTPTGTQTPTSTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQAPTPT 1452
            T    GT    ++  TT T ++   TP+ +  T T  P   +T  TPT T   T  P+ +
Sbjct: 3769 TRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSV-TAIPSSS 3827

Query: 1453 AITTTSTVTPTPTPTGTQ---TPTTTPITT------TTTVTPTPTPTGTQTPTPTAITTT 1503
              T  + ++ T TPT T    TP++TP T       TTT T T       TP+ T  T  
Sbjct: 3828 LGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAH 3887

Query: 1504 TTVTPTPTPTG-TQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQ 1562
            TT  PT T TG T TP+S+P T         TP    + T TP +  +TVTP+  P  T 
Sbjct: 3888 TTKVPTTTTTGFTATPSSSPGTAL-------TPPVWISTTTTPTTRGSTVTPSSIPGTTH 3940

Query: 1563 TPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKST---TVTPITTTT 1619
            T T    TTTT  T +       TP++   T+ TT TP P P +T +T   ++ P +  T
Sbjct: 3941 TATVLTTTTTTVATGS-----MATPSSSTQTSGTTHTP-PVPNTTATTHGRSLPPSSPHT 3994

Query: 1620 TVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGST--GPPTHTSTAPIAELTTSNPPPE 1677
              TA  + T     T      +T  + TP  TT +T    P  +S  P +  T S P P 
Sbjct: 3995 VRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPG 4054

Query: 1678 SSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPT-APTTT 1722
            ++TP  +R TS      TT  +T  P+   TST  PS+PT AP TT
Sbjct: 4055 TTTPGHTRGTS-----RTT--ATATPSKTRTSTLLPSSPTSAPITT 4093



 Score =  173 bits (438), Expect = 2e-42
 Identities = 201/718 (27%), Positives = 280/718 (38%), Gaps = 183/718 (25%)

Query: 1298 TQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTP------------ITTTTT- 1344
            T PT   +T T + TP  + T+T +T T T T    +  TP            +TTTTT 
Sbjct: 3194 TTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTG 3253

Query: 1345 --VTPTPTPTGTQT------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1396
               TP+ +P   +T       TTTP T  +TVTP+  P  T TPT    TTTT  T +  
Sbjct: 3254 FTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMA 3313

Query: 1397 PTGTQTPTS-------TPITTTTTVTPTPTPTGTQTPTT--------------------- 1428
               + T TS        P TT TT   + +P+   T  T                     
Sbjct: 3314 TPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTG 3373

Query: 1429 ---TPITTTTTV----------------TPTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
               TP  TT T                 T +P   GT  P  T  T+ +T T TP+ T T
Sbjct: 3374 TSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRT 3433

Query: 1470 QT-----PTTTPITTTTTVT---------------PTPTPTGTQTPTPTAITTTTTVT-- 1507
             T     PT+ PITT  T+                P P P+G    T + I         
Sbjct: 3434 STLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCE 3493

Query: 1508 -PTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPT------------------------ 1542
             P       Q     P+     V       G                             
Sbjct: 3494 QPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH 3553

Query: 1543 -PTPISTTTTVTPTPTP------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTT 1595
             P+  +T++T TP+ TP      T   T  TT  TT +T  P+ TP GT  P  VL +T 
Sbjct: 3554 CPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTP-GTAPPPKVLTSTA 3612

Query: 1596 TTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGST 1655
            TT    PT TS+K+T+ +   T TT+   P  T T T      ST T+ TP P+ T G+T
Sbjct: 3613 TT----PTATSSKATSSSSPRTATTL---PVLTSTATK-----STATSFTPIPSFTLGTT 3660

Query: 1656 GPPTHTSTAPIAELTTS-----NPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTST 1710
            G         + E TT+     +    SSTP+T+ +++   T++TT  +T   ++   S+
Sbjct: 3661 GT--------LPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRAT--SSMSTPSS 3710

Query: 1711 APPST------PTAPTTTSGGHTLSPPPST-----------TTSPPGTPTRGTTTGSSSA 1753
             P +T       TA TTT+     + P ST           TT+    PT  T T SS+ 
Sbjct: 3711 TPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTR 3770

Query: 1754 PTPSTVQTTTTSAWTPT-----PTPLSTPS------IIRTTGLRPYPSSVLICCVLNDTY 1802
             T  T++  T++A TPT      TP S+P        +R+T   P  +SV     +  + 
Sbjct: 3771 ATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSV---TAIPSSS 3827

Query: 1803 YAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTP 1860
                    + T   T      + S T E  + S   T   T T +++T + + PSSTP
Sbjct: 3828 LGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLT--TTTTTTRATGSVATPSSTP 3883



 Score =  171 bits (432), Expect = 1e-41
 Identities = 190/667 (28%), Positives = 259/667 (38%), Gaps = 139/667 (20%)

Query: 1300 PTTMTTTTTENPTPTPITTTTTVTPTPTPT---STQSTTPTPITTTTTVTPTPTPTGTQT 1356
            P TM TT   +  P+   T  T   + T     +T  T P+ +T+ T    T T   +  
Sbjct: 2829 PNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTP 2888

Query: 1357 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----PTSTPITTT 1411
              ++P  ++ T    P+P GT TP  T  T+ TT T TP+ T T T     PTS PITT 
Sbjct: 2889 ALSSPHPSSRTTESPPSP-GTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTV 2947

Query: 1412 TTVT---------------PTPTPTGTQTPTTTPITTTTTVT---PTPTPTGTQAPTPTA 1453
             T+                P P P+G    T + I          P       QA     
Sbjct: 2948 VTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVP 3007

Query: 1454 ITTTSTVTPTPTPTGTQTPTTTPI---------------------TTTTTVTPTPTPTGT 1492
            +     V       G        +                      +T   + T  P+ T
Sbjct: 3008 LRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSST 3067

Query: 1493 QTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTV 1552
               T      TTT T T +   T TP+STP TT     P+ T T T      P  +T T 
Sbjct: 3068 PGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVT-----VPTGSTATA 3122

Query: 1553 TPTPTPTGT---QTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTP---TPTS 1606
            + T    GT    T  TTP  T++  TP  +P GT T    L +T TT T T     P+S
Sbjct: 3123 SSTQATAGTPHVSTTATTPTVTSSKATPFSSP-GTATALPALRSTATTPTATSFTAIPSS 3181

Query: 1607 TKSTTVTPITTTTTVTAT-PTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHT---- 1661
            +  TT T ++ TTT TAT  T T + TP  +  ST  T T T T  TGS   P+ T    
Sbjct: 3182 SLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTA 3241

Query: 1662 -STAPIAELTTSNPPPESSTPQTSRS-------TSSPLTESTTLLSTLPPAIEMTSTAPP 1713
             +T  +   TT      SS+P T+R+       T++P T  +T+    P +I  T+  P 
Sbjct: 3242 HTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVT---PSSIPGTTHTPT 3298

Query: 1714 STPTAPTTTSGGHTLSPPPSTTTS-----PPGTPTRGTTTGSSSAPT-PSTVQTTTTSAW 1767
               T  TT + G   +P  ST TS     PP   T  TT G S +P+ P TV+T  TSA 
Sbjct: 3299 VLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSAT 3358

Query: 1768 TPT--PTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSL 1825
            + T   T ++ PS    TG    P++                     T G T +      
Sbjct: 3359 SGTLGTTHITEPS----TGTSHTPAA---------------------TTGTTQH------ 3387

Query: 1826 SCTLEFYNWSCP--STPSPTPTPSKSTPTP-------------SKPSSTPSKPTPGTKPP 1870
                     S P  S+P P+   ++S P+P             +  ++TPSK    T  P
Sbjct: 3388 ---------STPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLP 3438

Query: 1871 ECPDFDP 1877
              P   P
Sbjct: 3439 SSPTSAP 3445



 Score =  159 bits (401), Expect = 5e-38
 Identities = 91/265 (34%), Positives = 136/265 (51%), Gaps = 32/265 (12%)

Query: 697 CVSGCVCPDG--LMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQ 754
           CV+GC CP+G  L D G+ GCV   +C CV+N   Y+ GA    DC  CTC  GRW C +
Sbjct: 368 CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQE 427

Query: 755 AVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCG-TT 813
             C GTCS+ G  H+ TFDGK Y   G CSYV  +  C  +    +F+++ E   CG T 
Sbjct: 428 VPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKP-CDSS----AFTVLAELRRCGLTD 482

Query: 814 GVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGH---HVAYTTREVGQ-----------YL 859
             TC K++        L L+    VV+ +  G    +  YT   +             ++
Sbjct: 483 SETCLKSV-------TLSLDGAQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFI 535

Query: 860 VVESSTGIIVIWDKRTT--VFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELD 917
           + ++S G+ +      T  +F++LAP  +G  CGLCGNF+    +DF T   +V ++   
Sbjct: 536 IAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAA 595

Query: 918 FGNSWKEAPTCPDVSTN-PEPCSLN 941
           F N++K    CP++  +  +PCSL+
Sbjct: 596 FFNTFKTQAACPNIRNSFEDPCSLS 620



 Score =  135 bits (341), Expect = 4e-31
 Identities = 122/432 (28%), Positives = 180/432 (41%), Gaps = 60/432 (13%)

Query: 761  CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKA 820
            CS +GS HY TFDG  + F G C+YV   ++CG  ++   F+I               ++
Sbjct: 81   CSTWGSFHYKTFDGDVFRFPGLCNYV-FSEHCG--AAYEDFNIQLRR---------SQES 128

Query: 821  IKIFMGRTELKLEDKHRVVIQRDEG------HHVAYTTREVG-------QYLVVESSTGI 867
                + R  +K++    VVIQ  +G      H V     + G        Y  VE+  G+
Sbjct: 129  AAPTLSRVLMKVDG---VVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGL 185

Query: 868  IVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK-EAP 926
            +++W+   ++ ++L   Y    CGLCG+F+           H    + ++FGN  K + P
Sbjct: 186  VLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVS-ELLSHNTKLTPMEFGNLQKMDDP 244

Query: 927  TCPDVSTNPEPCSLNPHRRSWAEKQCS-ILKSSVFSICHSKVDPKPFYEACVHDSCSCDT 985
            T       PEP    P   S     C  +L   +FS C + VD   + EAC  D C C+ 
Sbjct: 245  TEQCQDPVPEP----PRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCED 300

Query: 986  GGDCECFCSAVASYAQECTKEGAC-VFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFE 1044
                 C C  +A Y+++CT  G     WR PD CP  C      HEC     PC     +
Sbjct: 301  TDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECR---SPCA----D 353

Query: 1045 TCRTINGIHSNISVSY-LEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASV 1103
            TC   N  HS     + + GC+  CP+   + +     CV   KC C      Y PGA+ 
Sbjct: 354  TCS--NQEHSRACEDHCVAGCF--CPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409

Query: 1104 PTEETCKSCVCTN---SSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSIT 1160
             T+  C +C C+    S Q V  P    +L       F      G   TV  H +   + 
Sbjct: 410  STD--CTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTF-----DGKQYTV--HGDCSYVL 460

Query: 1161 TRPSTLTTFTTI 1172
            T+P   + FT +
Sbjct: 461  TKPCDSSAFTVL 472



 Score =  131 bits (330), Expect = 8e-30
 Identities = 152/608 (25%), Positives = 238/608 (39%), Gaps = 101/608 (16%)

Query: 619  CSCYHRGLYLEAGDVVVRQEERCVCRDGRL---HCRQIRLIGQSCTAPK-IHMDCSNLTA 674
            C C   G +   G+V+  + +R  C    +   HC   R  G   T+P  +     +  +
Sbjct: 5265 CFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSSPS 5324

Query: 675  LATSKPRALSCQTLAAGYYHTEC-VSGCVCPDG--LMDDGRGGCV--VEKECPCVHNNDL 729
             A     A+  + +   +    C V+ CV  +   L+D      V  V K  P   ++  
Sbjct: 5325 PAPGCDNAIPLRQVNETWTLENCTVARCVGDNRVVLLDPKPVANVTCVNKHLPIKVSDP- 5383

Query: 730  YSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQ 789
             S       +C  C C  GR +   A   G CS++G  HY TFDG  Y F G+C+YV ++
Sbjct: 5384 -SQPCDFHYECE-CECVGGRGITPGA---GICSMWGGSHYSTFDGTSYTFRGNCTYVLMR 5438

Query: 790  DYCGQNSSLGSFSIITENVPCGTTGVT------CSKAIKIFMGRTELKLEDKHRVVIQRD 843
            +    ++  G+ S+  +N  C  +         C +A+ I     ++ L     +V  ++
Sbjct: 5439 EI---HARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVT--MVHGKE 5493

Query: 844  EGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKL-----APSYKGTVC-------- 890
            EG  + +    V       S  G++V     TT+ + +     + ++ G V         
Sbjct: 5494 EGL-ILFDQIPVSSGF---SKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSL 5549

Query: 891  ------GLCGNFDHRSNNDFTTRDHMVVSSELDFGNSW------------------KEAP 926
                  G CG   +   +D   RD    +S  D   +W                    +P
Sbjct: 5550 FHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASP 5609

Query: 927  TCPDVST-NPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDT 985
              P  ST  P PC   P         C ++ S VF+ CH+ V P PF+ AC+ D C    
Sbjct: 5610 AAPVSSTPTPTPCPPQP--------LCDLMLSQVFAECHNLVPPGPFFNACISDHCR--- 5658

Query: 986  GGDCECFCSAVASYAQECTKEGACVFWR--TPDLCPIFCDYYNPPHECEWHYEPCGNRSF 1043
             G  E  C ++ +YA+ C   G C  WR  T  LC + C    PP +    Y+PCG    
Sbjct: 5659 -GRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTC----PPTKV---YKPCGPIQP 5710

Query: 1044 ETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASV 1103
             TC + N   S       EGC+  CP+D+ ++   +  CV A  C C   D  +P     
Sbjct: 5711 ATCNSRN--QSPQLEGMAEGCF--CPEDQILFNAHMGICVQA--CPCVGPD-GFPKFPGE 5763

Query: 1104 PTEETCKSCVCTNSS-QVVCRP----EEGKILNQTQDGAFCYWEICGPNGTVEKHFNICS 1158
                 C+SCVC   S  V C+P     +G+     + G          N    +   +C+
Sbjct: 5764 RWVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCN 5823

Query: 1159 ITTRPSTL 1166
             TT P +L
Sbjct: 5824 TTTCPQSL 5831



 Score =  115 bits (288), Expect = 6e-25
 Identities = 124/519 (23%), Positives = 200/519 (38%), Gaps = 65/519 (12%)

Query: 1915 TCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPS 1974
            TCS GL           C    C   C+  G  H  T+D   Y   G+C+YVL ++ + S
Sbjct: 1067 TCSGGLWQ---------CQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADS 1117

Query: 1975 VDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKT-----VHMMPMQVQVQVNRQAV 2029
              +F V  +   C   D  +C + + +  +  +  I+      V +  +  Q+ ++   +
Sbjct: 1118 --SFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANI 1175

Query: 2030 ALPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRL-PYHRFGNNTKGQCGTCTNT 2088
             L        V Q+G+   + +  + ++  +      VRL P H+      G CG     
Sbjct: 1176 TLFTPSSFFIVVQTGLGLQLLVQLVPLMQVF------VRLDPAHQ--GQMCGLCGNFNQN 1227

Query: 2089 TSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCT 2148
             +DD    SG + +   A A+ W     ++  C ++ ++ + P            H    
Sbjct: 1228 QADDFTALSGVVEATGAAFANTW----KAQAACANARNSFEDPCSLSVENENYARH---- 1279

Query: 2149 PSPLCQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALCAQQN 2205
                C  + D  S F++CH+++ P+ ++  C+FD+C    S    CA+L +Y   CA + 
Sbjct: 1280 ---WCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKG 1336

Query: 2206 ICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQ----QNNTVLVEGCFCPEG 2260
            + L DWR+      +  CP  + Y     A +PTC+  S        + V V+GC CP G
Sbjct: 1337 VQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAG 1396

Query: 2261 TMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVT 2320
            T     G  V  + C C     V    GE    +   C C  G    +      S +  T
Sbjct: 1397 TFLNDAGACVPAQECPCYAHGTVLAP-GEVVHDEGAVCSCTGGKLSCL----GASLQKST 1451

Query: 2321 HCVEDGTYLATEVNPADT-------CCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGR 2373
             C     YL    + A T        C+     C ++ C     VCP G         G 
Sbjct: 1452 GCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHC-VSGCVCPPGLVSDGS---GG 1507

Query: 2374 CCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDK 2412
            C      E    CVH  A Y+PG  +    C  C C ++
Sbjct: 1508 CI----AEEDCPCVHNEATYKPGETI-RVDCNTCTCRNR 1541



 Score =  110 bits (275), Expect = 2e-23
 Identities = 109/420 (25%), Positives = 169/420 (40%), Gaps = 56/420 (13%)

Query: 340 AQADLPKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAI 399
           +Q     T+  +  K   VV+  + GSVL+N   V LP   +   + + SSY        
Sbjct: 125 SQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSY-------- 176

Query: 400 GVRLQVQLAPVMQ------LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAG 453
             +++ +L  V+       L + LD     +  GLCG+FNG+     +  S   + T   
Sbjct: 177 -TKVEARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVS-ELLSHNTKLTPME 234

Query: 454 FANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYK 513
           F N  K      D  +   DP      + +     C  L   +  F  C + VD   Y +
Sbjct: 235 FGNLQKMD----DPTEQCQDPVPEPPRNCSTGFGICEELLHGQL-FSGCVALVDVGSYLE 289

Query: 514 RCKYDTCNCQNNE--DCLCAALSSYARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLY 570
            C+ D C C++ +   C+C  L+ Y+R CT  G +   WR    C +    CPN+  +  
Sbjct: 290 ACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQ---KCPNNMQYHE 346

Query: 571 NLTTCQQTCRSLSEA---DSHCLEGFAPVDGCGCPDHTFLDEKGR--CVPLAKCSCYHRG 625
             + C  TC +   +   + HC      V GC CP+ T LD+ G+  CVP++KC+C + G
Sbjct: 347 CRSPCADTCSNQEHSRACEDHC------VAGCFCPEGTVLDDIGQTGCVPVSKCACVYNG 400

Query: 626 LYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTA-------------PKIHMDCSN- 671
                G         C C  GR  C+++   G +C+                +H DCS  
Sbjct: 401 AAYAPGATYSTDCTNCTCSGGRWSCQEVPCPG-TCSVLGGAHFSTFDGKQYTVHGDCSYV 459

Query: 672 LTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYS 731
           LT    S    +  +    G   +E    C+    L  DG    VV K    V  N +Y+
Sbjct: 460 LTKPCDSSAFTVLAELRRCGLTDSET---CLKSVTLSLDGAQTVVVIKASGEVFLNQIYT 516



 Score =  109 bits (273), Expect = 3e-23
 Identities = 147/633 (23%), Positives = 234/633 (36%), Gaps = 117/633 (18%)

Query: 1796 CVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSK 1855
            C  + T  APGE V++   G  C      LSC             S   +   + P    
Sbjct: 1413 CYAHGTVLAPGEVVHDE--GAVCSCTGGKLSCL----------GASLQKSTGCAAPMVYL 1460

Query: 1856 PSSTPSKPTPGTKP-PECPDFD--------------PPRQENETWWLC----DCFMATCK 1896
              S  S  TPG +    C   D              PP   ++    C    DC    C 
Sbjct: 1461 DCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDC---PCV 1517

Query: 1897 YNNTV----EIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTF 1952
            +N       E ++V+C      TC N     R E     C H  C   C  +GD H++TF
Sbjct: 1518 HNEATYKPGETIRVDCNTC---TCRNR----RWE-----CSHRLCLGTCVAYGDGHFITF 1565

Query: 1953 DGLYYSYQGNCTYVLVEEI---SPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEV- 2008
            DG  YS++G+C Y+L ++    + +   F +  +N  C      +C + + +  E +   
Sbjct: 1566 DGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTG-TTCSKAIKLFVEVRTAP 1624

Query: 2009 LIKTVHMM---PMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE-----------L 2054
             + T       P   +  V  +    P + Y L + +     V   P            +
Sbjct: 1625 AVSTPDPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGI 1684

Query: 2055 GVLVSYNGLSFS--------VRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEA 2106
             +++  +G++ S        +RL +  +     G CG   +   +D    S  +V +   
Sbjct: 1685 FLVIETHGMAVSWDRKTSVFIRL-HQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALE 1743

Query: 2107 AADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHA 2166
              + W ++    P CP + +  K P           P +       C ++    FA C +
Sbjct: 1744 FGNSWKLS----PSCPDALAP-KDPCTA-------NPFRKSWAQKQCSILHGPTFAACRS 1791

Query: 2167 LVPPQHYYDACVFDSCFM-PGSSLE--CASLQAYAALCAQQNICLDWRNHTHGACLVECP 2223
             V    YY+ACV D+C    G   E  C ++ AYA  C    +C+ WR  T   C + C 
Sbjct: 1792 QVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWR--TPDTCPLFCD 1849

Query: 2224 SHR-------EYQACGPAEEPTCKSSSSQ-QNNTVLVEGCF--CPEGTMNYAPGFDVCVK 2273
             +         YQ CG     TC++ S     +   +EGC+  CP     +      CV 
Sbjct: 1850 FYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVA 1909

Query: 2274 TCGCVGPDNVPREFGEHFEF--DCKNCVCLEGGSGIIC----QPKRCSQKPVTHCVEDGT 2327
             CGC   D    + G       +C++C C    SGI C    +   C+ +  T+  +D  
Sbjct: 1910 QCGCYDKDGNYYDVGARVPTAENCQSCNCTP--SGIQCAHSLEACTCTYEDRTYSYQDVI 1967

Query: 2328 YLATEVNPADTCCNITVCKCNTSLCKEKPSVCP 2360
            Y  T+   A   C I +C  N ++ + K   CP
Sbjct: 1968 YNTTDGLGA---CLIAICGSNGTIIR-KAVACP 1996



 Score =  108 bits (271), Expect = 5e-23
 Identities = 110/402 (27%), Positives = 165/402 (41%), Gaps = 49/402 (12%)

Query: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000
            C+ WG  HY TFDG  + + G C YV  E    + ++F + +       + + + P    
Sbjct: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRR-----SQESAAPTLSR 135

Query: 2001 VRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSY 2060
            V  +   V+I+       +  V VN   V LP+ + G+ + QS  +Y      LG+++ +
Sbjct: 136  VLMKVDGVVIQLT-----KGSVLVNGHPVLLPFSQSGVLIQQSS-SYTKVEARLGLVLMW 189

Query: 2061 NGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPH 2120
            N     +     ++ N T G CG          +L     ++  E    Q + +DP    
Sbjct: 190  NHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKM-DDP---- 244

Query: 2121 CPHSSSTTKRPAVTVPGGGKTTPHKDC-TPSPLCQ-LIKDSLFAQCHALVPPQHYYDACV 2178
                   T++    VP      P ++C T   +C+ L+   LF+ C ALV    Y +AC 
Sbjct: 245  -------TEQCQDPVP-----EPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACR 292

Query: 2179 FDSCFMPGSSL---ECASLQAYAALCAQQN-ICLDWRNHTHGACLVECPSHREYQACGPA 2234
             D CF   + L    C +L  Y+  C     +  DWR      C  +CP++ +Y  C   
Sbjct: 293  QDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDF--CPQKCPNNMQYHECRSP 350

Query: 2235 EEPTCKSSS-SQQNNTVLVEGCFCPEGTMNYAPGFDVC--VKTCGCV--GPDNVPREFGE 2289
               TC +   S+      V GCFCPEGT+    G   C  V  C CV  G    P   G 
Sbjct: 351  CADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP---GA 407

Query: 2290 HFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLAT 2331
             +  DC NC C   G    CQ   C   P T  V  G + +T
Sbjct: 408  TYSTDCTNCTC--SGGRWSCQEVPC---PGTCSVLGGAHFST 444



 Score = 98.2 bits (243), Expect = 9e-20
 Identities = 107/403 (26%), Positives = 156/403 (38%), Gaps = 53/403 (13%)

Query: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000
            C+ WGD HY TFDG  + + G C YV  E    + ++F V +              R L+
Sbjct: 733  CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQL-------------RRGLV 779

Query: 2001 -VRHETQEVLIKTVHMM--PMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVL 2057
              R     V+IK   ++       V +N Q   LPY + GL V QSG +Y+     L + 
Sbjct: 780  GSRPVVTRVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSG-DYIKVSIRLVLT 838

Query: 2058 VSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPS 2117
              +NG   ++     ++ N T G CG      + +        ++  +    Q L  D  
Sbjct: 839  FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKL--DGP 896

Query: 2118 KPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDAC 2177
               CP          + +P G  T     C      + +    FA+CHALV    Y  AC
Sbjct: 897  TEQCP--------DPLPLPAGNCTDEEGICH-----RTLLGPAFAECHALVDSTAYLAAC 943

Query: 2178 VFDSCFMPGSSLECASLQAYAALCAQQ-NICLDWRNHTHGACLVECPSHREYQACGPAEE 2236
              D C  P  +  CA+   Y+  CA       +WR      C   CP + ++Q CG    
Sbjct: 944  AQDLCRCP--TCPCATFVEYSRQCAHAGGQPRNWR--CPELCPRTCPLNMQHQECGSPCT 999

Query: 2237 PTCKS-SSSQQNNTVLVEGCFCPEGTM-----NYAPGFDVCVKTCGCV--GPDNVPREFG 2288
             TC +   +Q      V+GCFCP G       +      + +  C C   G    P   G
Sbjct: 1000 DTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSP---G 1056

Query: 2289 EHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLAT 2331
              F   C +C C   G    CQ   C   P T  V+ G +++T
Sbjct: 1057 TSFNTTCSSCTC--SGGLWQCQDLPC---PGTCSVQGGAHIST 1094



 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 88/343 (25%), Positives = 129/343 (37%), Gaps = 40/343 (11%)

Query: 27   GRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAE 86
            GR    G  +CS WG  HY TFDG  + F G C Y    +    +   +++L      A 
Sbjct: 5400 GRGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTAS 5459

Query: 87   APAGV------ESILLTIKDDTIYLT--------RHLAVLNGAVVSTPHYSPGLLIEKSD 132
            A A         ++ +  K   I LT          L + +   VS+     G+L+    
Sbjct: 5460 ATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLG 5519

Query: 133  AYTKVYS--RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSP 190
              T        G+++ +N +        + F N+T G CG     Q       DG   + 
Sbjct: 5520 TTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAAS 5579

Query: 191  LEFGNMQKI----NQPDVVCEDPE------EEVAPASCSEHRAECER-----LLTAEAFA 235
             +  +M K     +     C  P          AP S +     C       L+ ++ FA
Sbjct: 5580 CK--DMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFA 5637

Query: 236  DCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPG 295
            +C +LVP  P+  AC  D CR  G     C ++  ++  C  A G   +WR AT  +   
Sbjct: 5638 ECHNLVPPGPFFNACISDHCR--GRLEVPCQSLEAYAELC-RARGVCSDWRGATGGL--- 5691

Query: 296  ASKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPE 338
               TCP   VY   G     TC+    S    E   +GCFCPE
Sbjct: 5692 CDLTCPPTKVYKPCGPIQPATCNSRNQSPQL-EGMAEGCFCPE 5733



 Score = 79.3 bits (194), Expect = 5e-14
 Identities = 97/398 (24%), Positives = 140/398 (35%), Gaps = 55/398 (13%)

Query: 426  QGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYA 485
            +G CG     + DD     G   A+    A TW    S  D   W          +A+ A
Sbjct: 5555 EGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGC-WAPTGTP---PTASPA 5610

Query: 486  EHWCSLLKKTETP------------FGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAAL 533
                S    T  P            F  CH+ V P  ++  C  D  +C+   +  C +L
Sbjct: 5611 APVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISD--HCRGRLEVPCQSL 5668

Query: 534  SSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGF 593
             +YA  C A+GV    WR         +CP ++V+         TC S +++    LEG 
Sbjct: 5669 EAYAELCRARGVCS-DWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQ--LEGM 5725

Query: 594  APVDGCGCPDHTFLDEKGRCVPLAKCSCY-HRGLYLEAGDVVVRQEERCVCRDG--RLHC 650
            A  +GC CP+   L      + +  C C    G     G+  V   + CVC +G   + C
Sbjct: 5726 A--EGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQC 5783

Query: 651  RQIRLIGQSCTAPKIHMDCSNLTALATSKPRALS--CQTLAAGYYHTECVSGC-VCPDG- 706
            + +    Q    P     C+    +  ++PRA +  C         T C     VCP G 
Sbjct: 5784 KPLPCDAQGQPPP-----CNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQ 5838

Query: 707  --LMDDGRGGCVVEKECP---CVHNNDLYSSGAKI--KVDCNTCTCKRG-----RWVCTQ 754
              +     G C     C    C +N   Y  GA     + C+ CTC  G        C +
Sbjct: 5839 ESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQE 5898

Query: 755  AVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYC 792
              C+ T    G         +Y    G C    VQ  C
Sbjct: 5899 DACNNTTCPQGF--------EYKRVAGQCCGECVQTAC 5928



 Score = 52.8 bits (125), Expect = 5e-06
 Identities = 48/204 (23%), Positives = 91/204 (44%), Gaps = 16/204 (7%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C    C   C+  G  H+ TFDG  Y+  G+C+YVL +    S   F V  +   C   D
Sbjct: 425  CQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSA--FTVLAELRRCGLTD 482

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
              +C +++ +  +  +    TV ++    +V +N+    LP     + +++    +++  
Sbjct: 483  SETCLKSVTLSLDGAQ----TVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQ 538

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQ-CGTCTNTTS---DDCILPSGEIVSNCEAA 2107
              LG+ ++   L  +++L + +     +GQ CG C N  S   DD    SG +    EA 
Sbjct: 539  TSLGLQLNLQ-LVPTMQL-FMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVV----EAT 592

Query: 2108 ADQWLVNDPSKPHCPHSSSTTKRP 2131
            A  +     ++  CP+  ++ + P
Sbjct: 593  AAAFFNTFKTQAACPNIRNSFEDP 616



 Score = 40.8 bits (94), Expect = 0.018
 Identities = 37/124 (29%), Positives = 47/124 (37%), Gaps = 19/124 (15%)

Query: 2311 PKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMV 2370
            P  C QK    C  +  Y       ADTC N    +     C      CP G  +     
Sbjct: 331  PDFCPQK----CPNNMQYHECRSPCADTCSNQEHSRACEDHCVAG-CFCPEGTVLDDIGQ 385

Query: 2371 PGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCN 2430
             G C P     SK  CV+  A Y PG+  YS+ C +C C+            +C  VPC 
Sbjct: 386  TG-CVPV----SKCACVYNGAAYAPGA-TYSTDCTNCTCSG--------GRWSCQEVPCP 431

Query: 2431 TSCS 2434
             +CS
Sbjct: 432  GTCS 435



 Score = 35.4 bits (80), Expect = 0.75
 Identities = 26/100 (26%), Positives = 37/100 (37%), Gaps = 16/100 (16%)

Query: 2337 DTCCNITVCKCNTSLCKEKPSVCPLGFE--VKSKMVPGRCCPFYWCESKGVCVHGNAEYQ 2394
            DTC N    +     C +    CP G    V   +    C P   C     C HG   Y 
Sbjct: 1000 DTCSNPQRAQLCEDHCVDG-CFCPPGRSCTVLDDITHSGCLPLGQCP----CTHGGRTYS 1054

Query: 2395 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434
            PG+  +++ C  C C+          +  C  +PC  +CS
Sbjct: 1055 PGTS-FNTTCSSCTCSG--------GLWQCQDLPCPGTCS 1085



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 7/71 (9%)

Query: 1796 CVLNDTYYAPGEEVYNGTYG-DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTP------SK 1848
            C   D  Y+  + +YN T G   C    C  + T+     +CP TP+ TP          
Sbjct: 1954 CTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPGTPATTPFTFTTAWVPH 2013

Query: 1849 STPTPSKPSST 1859
            ST +P+ P ST
Sbjct: 2014 STTSPALPVST 2024



 Score = 32.7 bits (73), Expect = 4.9
 Identities = 19/41 (46%), Positives = 23/41 (56%)

Query: 1158 SITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLST 1198
            S  T  STL T  T  + TT  T  T T +T P+SSTV +T
Sbjct: 5185 STATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTT 5225


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score =  817 bits (2111), Expect = 0.0
 Identities = 599/1812 (33%), Positives = 827/1812 (45%), Gaps = 312/1812 (17%)

Query: 283  GNWRTATSAVSPGASKTCPGNLVYLESGSPCM--DTCSHLEVSS--LCEEHRMDGCFCPE 338
            G W   T    PG      G+ V      P     TC+++ + S  L E+  +   +   
Sbjct: 384  GRW-VCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKS 442

Query: 339  GAQADLPKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMA 398
            G        V ++   +++ +V   D  V  N     LP+ T + +VFR +S H+ ++ +
Sbjct: 443  GVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATS 502

Query: 399  IGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTW 458
             G+ L VQL P+ Q +VT+    +GQ +GLCGNFNG   DDF T+ G+ E T + F ++W
Sbjct: 503  FGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSW 562

Query: 459  KAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYD 518
            +A  +C   L+   DPCS++  +   AE  CS+L +T T F RCH+ V+PA +YKRC Y 
Sbjct: 563  RA-GNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQ 621

Query: 519  TCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQT 578
             CN +     +CAAL  Y  AC+ +GV+LWGWR  V N  +  C  +  F YN   C++T
Sbjct: 622  ACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTI-PCTGNTTFSYNSQACERT 680

Query: 579  CRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGL-YLEAGDVVVRQ 637
            C SLS+  + C     PVDGC CPD T+L++KG CV  A+C C   G  ++ A    V  
Sbjct: 681  CLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVIN 740

Query: 638  EERCVCRDGRLHCRQI-RLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGY--YH 694
               C C +GRL C Q  ++   SC APK    CS  +        A +CQ LA G     
Sbjct: 741  GITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVP 800

Query: 695  TECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQ 754
            T+C  GCVC +GL ++  G CV  +ECPC  +   Y  GA++  DC TC+C RGRW C Q
Sbjct: 801  TKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQ 860

Query: 755  AV-CHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTT 813
               C  TC++YG GH ITFDG+ + FDG+C Y+   D CG N S  +F I+TENV CG +
Sbjct: 861  GTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNS 920

Query: 814  GVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESST----GIIV 869
            GVTCS+AIKIF+G   + L D++  V    E  HV          LVV+ S      + +
Sbjct: 921  GVTCSRAIKIFLGGLSVVLADRNYTVT--GEEPHVQLGVTPGALSLVVDISIPGRYNLTL 978

Query: 870  IWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCP 929
            IW++  T+ I++A + +  +CGLCGNF+    +DF TR   V SSEL+  NSWKE+P C 
Sbjct: 979  IWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPLCG 1038

Query: 930  DVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC 989
            DVS   +PCSLN  RRSWAE++CS++ S  F+ CHSKV   P+YEACV D+C CD+GGDC
Sbjct: 1039 DVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDC 1098

Query: 990  ECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHE-------------CEWHYE 1036
            EC C AVA+YAQ C  +G CV WRTP  CPI+C +YN   +             C WHY+
Sbjct: 1099 ECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQ 1158

Query: 1037 PCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTH 1096
            PC                ++  S +EGCY  C +D   ++ +   CV      C    T 
Sbjct: 1159 PC---------LCPSQPQSVPGSNIEGCY-NCSQDE-YFDHEEGVCVP-----CMPPTTP 1202

Query: 1097 YPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNI 1156
             PP  + P   T  S           RP +              W + G + T+     +
Sbjct: 1203 QPP--TTPQLPTTGS-----------RPTQ-------------VWPMTGTSTTI----GL 1232

Query: 1157 CSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPS 1216
             S +T PS  +  T  + PT       T T++ PT+S+     P              P 
Sbjct: 1233 LS-STGPSPSSNHTPAS-PTQTPLLPATLTSSKPTASSGEPPRPTTAVT---------PQ 1281

Query: 1217 SGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQKPG 1276
            + S      T       P   +  +      +        Q     ++ L          
Sbjct: 1282 ATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTL----PTPATS 1337

Query: 1277 GVIP-MAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTP--ITTTTTVTPTPTPTSTQS 1333
            G  P +    N E+        T P     +TT   TP P   T  T    T T T+T+ 
Sbjct: 1338 GTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEY 1397

Query: 1334 TTPTPITTTTTVTPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTPTTTPITTTT 1389
            TTP     T   T +P   G+  P+T P+T T    TT  PTP+   T  PT  P  +T+
Sbjct: 1398 TTP----QTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTS 1453

Query: 1390 TVTP------TPT-------------PTGTQTPTSTPITTTTTVTP---TPTPTGT---- 1423
             VTP      TPT             PTGT  P +T   T +T T    TPT +GT    
Sbjct: 1454 LVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAH 1513

Query: 1424 ------QTPTT----------TPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPT 1467
                  +TPT+            +T T+T T TP PT T+  TP A T ++T +  P P 
Sbjct: 1514 SSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPF 1573

Query: 1468 GTQTP--------TTTPITTTT--TVTPTPTPTGTQTPTPTAI----------TTTTTVT 1507
             T +P        +T P+T T+  T T  PTP+  QT  PT +          +T T +T
Sbjct: 1574 TTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIT 1633

Query: 1508 PT-----------PTPTGT-QTPTSTPITTTTTVTPTPTPTGTQT----------PTPTP 1545
            PT             PTGT   PT+   T +T   PT T T + T           T T 
Sbjct: 1634 PTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTS 1693

Query: 1546 I--------------STTTTVTPTPTPTGTQTPTTT------------------------ 1567
            +              ++TT +TP PT TGT   T T                        
Sbjct: 1694 LHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHT 1753

Query: 1568 --------PITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTT 1619
                      T+TT++TP  T TGT+TP     + T++  PTP  T +  T  TPI++T 
Sbjct: 1754 SSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTG 1813

Query: 1620 TVTAT--------PTPTGTQT--PTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAEL 1669
             VTAT        PTP+   T  PT +P  +T+ V    TP+T +   PTHT  A  A +
Sbjct: 1814 PVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLV----TPSTHTVIIPTHTQMATSASI 1869

Query: 1670 ----TTSNPPPES------------STPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPP 1713
                T + PPP +             TP TS ++ SP + ST   ST  P    ++  P 
Sbjct: 1870 HSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPE 1929

Query: 1714 STPTAPT-----------------TTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA--- 1753
             TPT+ T                 TTS   +  P P TT SPP   +  ++TG  +A   
Sbjct: 1930 VTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSF 1989

Query: 1754 ------PTPSTVQTTTTSAWTPTPTPLSTPS----IIRT--------------TGLRPYP 1789
                  PTPS  QTT  +   P  T L TPS    II T              TG  P P
Sbjct: 1990 QTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPP 2049

Query: 1790 SSVLICCVLNDTYYAPGEEV-YNGTYGDTCYFVNCSLSCT-LEFYNWSCPSTPSPTPTPS 1847
            +++        T+ AP   V  +GT      F   + S + +   +W   ++ S  P+  
Sbjct: 2050 TTLK---ATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSP 2106

Query: 1848 KSTPTPSKPSST 1859
             +T  P   S+T
Sbjct: 2107 ITTQLPHLSSAT 2118



 Score =  214 bits (545), Expect = 9e-55
 Identities = 235/808 (29%), Positives = 329/808 (40%), Gaps = 125/808 (15%)

Query: 1163 PSTLTTFTTITLPTTPTTFTTTT-----------TTTTPTSSTVLSTTPKLCCLWSDWIN 1211
            P T  T TT   PT  +T   TT           T TT T +T   TTP+          
Sbjct: 1352 PGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPT 1411

Query: 1212 EDHPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHL-----SLEQLGQKVQLVCDVSVGL 1266
               P   +      +F      P      +    H+     SL        +    +   
Sbjct: 1412 AGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMA 1471

Query: 1267 ICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMT----TTTTENPTPT-------- 1314
               +    P G IP    L    +      +T  T+ T    ++ + N TPT        
Sbjct: 1472 TSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSS 1531

Query: 1315 ----PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTP--------TTTPI 1362
                 +T T+T T TP PTST++ TP   T + T +  P P  T +P        +T P+
Sbjct: 1532 THHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPM 1591

Query: 1363 TT----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTSTPITT--TT 1412
            T     TTT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  TS  I +  T 
Sbjct: 1592 TATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTG 1651

Query: 1413 TVTPTPTPTGTQTPTTTPITTTTT-------------VTPTPTPTGTQAPTPTAITTTST 1459
            T+ P  T   T +  T P  T TT              T T   + T +      T+TST
Sbjct: 1652 TIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTST 1711

Query: 1460 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAI--------------TTTTT 1505
               TP PT T TP   P+T TT+ T     + +   T T++              T+TT+
Sbjct: 1712 TNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTS 1768

Query: 1506 VTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPIST----------TTTVTPT 1555
            +TP  T TGT+TP +   + T++  PTP  T +     TPIS+          TTT  PT
Sbjct: 1769 ITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPT 1828

Query: 1556 PTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTVLITTTTTMTPTPTPTSTKST- 1610
            P+   T  PT  P  +T+ VTP+      PT TQ  T+  I +  T T  P PT+ K+T 
Sbjct: 1829 PSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGT-IPPPTTIKATG 1887

Query: 1611 ---TVTPITTTTTVTA-TPTPTGT-QTPTMIPISTTTTVTPTPTPTTGSTGPPTHTST-- 1663
               T  P+T TT+ T+ +P+   T +T T +P  T++T  P  TPT+ +   P HTST  
Sbjct: 1888 STHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGT 1947

Query: 1664 -APIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP-PAIEMTSTAPPSTPTAPTT 1721
              P+A  T+++    SS   T  +T SP T S+   ST P  A    +T    TP+ P T
Sbjct: 1948 RTPVAHTTSAS----SSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQT 2003

Query: 1722 TSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPT------PTPLS 1775
            T   H   PP ST+   P T T   TT +  A + S   T T +   PT       T  +
Sbjct: 2004 TLPTHV--PPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTA 2061

Query: 1776 TPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWS 1835
             P  + T+G     SS       +    +      N +          S   T +  + S
Sbjct: 2062 PPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPP------SSPITTQLPHLS 2115

Query: 1836 CPSTPSPTPT--PSKSTPTPSKPSSTPS 1861
              +TP  T     S  +P+PS PS+  S
Sbjct: 2116 SATTPVSTTNQLSSSFSPSPSAPSTVSS 2143



 Score =  213 bits (542), Expect = 2e-54
 Identities = 202/632 (31%), Positives = 274/632 (43%), Gaps = 73/632 (11%)

Query: 1298 TQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITT---TTTVTPTPTPTGT 1354
            T P+  +  T  +PT TP+   T  +  PT +S +   PT   T   T+ + PT T   T
Sbjct: 1236 TGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRST 1295

Query: 1355 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTST----PITT 1410
             T  T    TT     T +P  T T  +T  TT T  TP  + T    P ST    P TT
Sbjct: 1296 ATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTT 1355

Query: 1411 TTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTST--VTPTPTPT 1467
             T  T P PTP  T  PTT      T  T T T   TQ  T T  TT  T   T +P   
Sbjct: 1356 ATQTTGPRPTPASTTGPTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTA 1412

Query: 1468 GTQTPTTTPITTT----TTVTPTPTPTGTQTPTPTAITTTTTVTP------TPT------ 1511
            G+  P+T P+T T    TT  PTP+   T  PT     +T+ VTP      TPT      
Sbjct: 1413 GSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMAT 1472

Query: 1512 -------PTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQT- 1563
                   PTGT  P +T   T +T T  P    T   +    S +T  TPT   + T + 
Sbjct: 1473 SASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSST 1532

Query: 1564 --PTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTV 1621
              P  TP T+TTT+TP PT T T+TP     + T++  P P  T +  T  +P ++T  +
Sbjct: 1533 HHPEVTP-TSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPM 1591

Query: 1622 TAT--------PTPTGTQT--PTMIPISTTTTVTPTPTPTTGSTGPPTH---TSTAPIAE 1668
            TAT        PTP+  QT  PT +P  +T+ V    TP+T +   PTH    ++A I  
Sbjct: 1592 TATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLV----TPSTHTVITPTHAQMATSASIHS 1647

Query: 1669 LTTSNPPPESSTPQTSRSTSSPLTESTT-----LLSTLPPAIEMTS--TAPPSTPTAPTT 1721
            + T   PP ++   T  + ++P    TT      LS+L  A   TS  +   ST  A  T
Sbjct: 1648 MPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEAT 1707

Query: 1722 TSGGHTLSPPPSTTTSPPGTPTRGTTTGS----SSAPTPSTVQTTTTSAWTPTPTPLSTP 1777
            ++    ++P P++T +PP T T   T+ S    S+A T +++ + T+S   P  T  ST 
Sbjct: 1708 STSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTT 1767

Query: 1778 SII---RTTGLR-PYPSSVLICCVLNDTYYAPGEEVYNGT-YGDTCYFVNCSLSCTLEFY 1832
            SI     +TG R P   +         T +         T    T      S   T  + 
Sbjct: 1768 SITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYP 1827

Query: 1833 NWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPT 1864
              S P T  PT  PS ST   +  + T   PT
Sbjct: 1828 TPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPT 1859



 Score =  211 bits (537), Expect = 8e-54
 Identities = 234/812 (28%), Positives = 348/812 (42%), Gaps = 167/812 (20%)

Query: 1160 TTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGS 1219
            +T P T T+F T T   TP+   TT  T  P  ST L  TP    +    I   H    +
Sbjct: 1587 STGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSL-VTPSTHTV----ITPTHAQMAT 1641

Query: 1220 DDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQKPGGVI 1279
                     G    P  +  ++    H +              ++ L      Q    + 
Sbjct: 1642 SASIHSMPTGTIPPPTTL--KATGSTHTA-------------PTMTLTTSGTSQALSSLN 1686

Query: 1280 PMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPT---PITTTTTVTPTPTPTSTQSTTP 1336
                  +   +          +T TT  T NPT T   P+T TT+ T     + + + T 
Sbjct: 1687 TAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTS 1746

Query: 1337 TPI--------------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1382
            T +              T+TT++TP  T TGT+TP     + T++  PTP  T +    T
Sbjct: 1747 TSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGT 1806

Query: 1383 TPITTT----------TTVTPTPTPTGTQTPTSTPITTTTTVTPT------PT------- 1419
            TPI++T          TT  PTP+   T  PT  P  +T+ VTP+      PT       
Sbjct: 1807 TPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATS 1866

Query: 1420 ------PTGTQTPTTTPITTTTTVTP---TPTPTGTQAPTPTAITTTSTVTPTPTPTG-T 1469
                  PTGT  P TT   T +T T    TPT +GT + +P++ +T  T T  P  T  T
Sbjct: 1867 ASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGT-SQSPSSFSTAKTSTSLPYHTSST 1925

Query: 1470 QTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTP-----TPTGTQTPTST-PI 1523
              P  TP T+TT +TP  T TGT+TP     + +++  PTP      PTG+   +ST P+
Sbjct: 1926 HHPEVTP-TSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPM 1984

Query: 1524 TTT----TTVTPTPTPTGTQTPTPTPISTTTTVTPT-------------------PTPTG 1560
            T T    TT  PTP+   T  PT  P  +T+ VTP+                    TPTG
Sbjct: 1985 TATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTG 2044

Query: 1561 TQTPTTT-----------PITTTTTVT-PTPTPTGTQTPTTVLITTT------TTMTPTP 1602
            T  P TT           P+T TT+ T  T +   T T ++  I+++      ++  P  
Sbjct: 2045 TVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPS 2104

Query: 1603 TPTSTK----STTVTPITTTTTVTA--TPTPTGTQT-PTMIPISTTTTVTPTPTPTTGST 1655
            +P +T+    S+  TP++TT  +++  +P+P+   T  + +P S ++  T +P+  T S+
Sbjct: 2105 SPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSS 2164

Query: 1656 --GPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPL-----TESTTLLSTLPPAIE-- 1706
                P H++T     L++ +    S+ P T+  ++SPL       STT+ +TLP  I   
Sbjct: 2165 FVSAPVHSTT-----LSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSP 2219

Query: 1707 --MTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTT 1764
              +++  P ST T   T S     S   S+T + P TP   TT  + +AP  S+  TT+ 
Sbjct: 2220 FTLSALLPISTVTVSPTPS-----SHLASSTIAFPSTPR--TTASTHTAPAFSSQSTTSR 2272

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            S    T  P S   +  T+G+   P+S     V N T   PG      T   T  F+  S
Sbjct: 2273 STSLTTRVPTS-GFVSLTSGVTGIPTSP----VTNLTTRHPGP-----TLSPTTRFLTSS 2322

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKP 1856
            L+        +  STP+  P  S  TPTP+ P
Sbjct: 2323 LT--------AHGSTPASAPVSSLGTPTPTSP 2346



 Score =  205 bits (521), Expect = 5e-52
 Identities = 224/740 (30%), Positives = 312/740 (42%), Gaps = 188/740 (25%)

Query: 1305 TTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTP------- 1357
            T++T +P  TP +TTT    TP PTST++ TP   T + T +  P P  T +P       
Sbjct: 1529 TSSTHHPEVTPTSTTTI---TPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPF 1585

Query: 1358 -TTTPITTT----TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPT---------- 1396
             +T P+T T    TT  PTP+   T  PT  P  +T+ VTP      TPT          
Sbjct: 1586 SSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASI 1645

Query: 1397 ---PTGT-QTPTSTPITTTTTVTPTPTPTGTQTP----------TTTPI----------- 1431
               PTGT   PT+   T +T   PT T T + T           T+T +           
Sbjct: 1646 HSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAE 1705

Query: 1432 ---TTTTTVTPTPTPTGTQAPTPT---------AITTTSTVTPTPTPTGTQTPTTTPITT 1479
               T+TT +TP PT TGT   T T         + +T  T T   + T +        T+
Sbjct: 1706 ATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTS 1765

Query: 1480 TTTVTPTPTPTGTQTPTPTAITTTTTVTPTP-----TPTGTQTPTST-PITTT----TTV 1529
            TT++TP  T TGT+TP     + T++  PTP      PTGT   +ST P+T T    TT 
Sbjct: 1766 TTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTT 1825

Query: 1530 TPTPTPTGTQTPTPTPISTTTTVTPT------PT-------------PTGTQTPTTTPIT 1570
             PTP+   T  PT  P  +T+ VTP+      PT             PTGT  P TT   
Sbjct: 1826 YPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKA 1885

Query: 1571 TTTTVTP---TPTPTGT-QTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPT 1626
            T +T T    TPT +GT Q+P++     T+T  P  T +ST    VTP T+TT +T   T
Sbjct: 1886 TGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHT-SSTHHPEVTP-TSTTNITPKHT 1943

Query: 1627 PTGTQTPTMIPISTTTTVTPTP----TPTTGS-----TGPPTHTS----------TAPIA 1667
             TGT+TP     S +++  PTP    +P TGS     TGP T TS          + P  
Sbjct: 1944 STGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQT 2003

Query: 1668 ELTTSNPPPESS-----------TPQTSRSTSSPLTESTTLLSTLPP-----AIEMTSTA 1711
             L T  PP  +S           T  T  +TS+ +  + T   T+PP     A   T TA
Sbjct: 2004 TLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPT--GTVPPPTTLKATGSTHTA 2061

Query: 1712 PPSTPTAPTTTSGGHTLSP--------------PPSTTTSPPGTPTRGTTTGSSSAPTPS 1757
            PP T T   T+    + S               P ++++ PP +P        SSA TP 
Sbjct: 2062 PPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPV 2121

Query: 1758 TVQTTTTSAWTPTPTPLSTPSII--------RTTGLRPYPSSVLICCVLNDTYYAPGEEV 1809
            +     +S+++P+P+  ST S          +T+      SS  +   ++ T  + G   
Sbjct: 2122 STTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHS 2181

Query: 1810 YNGTYGDTCYF-----------VNCSLSCTLEFYNWSCPST-----------PSPTPTPS 1847
               T+  T               + ++  TL  +  S P T            SPTP+  
Sbjct: 2182 SLSTHPTTASVSASPLFPSSPAASTTIRATLP-HTISSPFTLSALLPISTVTVSPTPSSH 2240

Query: 1848 KSTPT---PSKPSSTPSKPT 1864
             ++ T   PS P +T S  T
Sbjct: 2241 LASSTIAFPSTPRTTASTHT 2260



 Score =  192 bits (489), Expect = 3e-48
 Identities = 184/602 (30%), Positives = 255/602 (42%), Gaps = 58/602 (9%)

Query: 1307 TTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTT 1366
            TT  P  TP   TT   PT     T ++T   + ++T  +P+   T   +PT TP+   T
Sbjct: 1200 TTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPA-SPTQTPLLPAT 1258

Query: 1367 TVTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQT 1425
              +  PT +  + P  TT +T   T    PT T   T T   +T  TT     T +   T
Sbjct: 1259 LTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATT 1318

Query: 1426 PTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTP 1485
             T    T TT   PTP  +GT   +PT   +T+   P  T T T  P  TP +TT   TP
Sbjct: 1319 STAQSTTRTTMTLPTPATSGT---SPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTP 1375

Query: 1486 TPTPTGTQTPTPTAITTTTTVTPTP-TPTGTQTPTS--TPITTTTTVTPTPTPTGTQTPT 1542
             P      T T T  T TTT   TP TP  T +P +  +P+ +T  VT T     T  PT
Sbjct: 1376 QPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPT 1435

Query: 1543 PTPISTTTTVTPTPTPTGTQTPTT-TPITTT-----TTVTPTPTPTGTQTPTTVLITTTT 1596
            P+   TT      P  T   TP+T T IT T     T+ +    PTGT  P T L  T +
Sbjct: 1436 PSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGS 1495

Query: 1597 TMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQT---PTMIPISTTTTVTPTPTPTTG 1653
            T T  P   +T  T+    + +T  T T   + T +   P + P STTT +TP PT T  
Sbjct: 1496 THTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTT-ITPNPTSTRT 1554

Query: 1654 STGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP-PAIEMTSTAP 1712
             T P  HT++A     T+S PPP         +T SP T S+   ST P  A    +T  
Sbjct: 1555 RT-PVAHTNSA-----TSSRPPPPF-------TTHSPPTGSSPFSSTGPMTATSFKTTTT 1601

Query: 1713 PSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA-------------PTPSTV 1759
              TP+ P TT   H   PP ST+   P T T  T T +  A             P P+T+
Sbjct: 1602 YPTPSHPQTTLPTHV--PPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTL 1659

Query: 1760 QTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVY------NGT 1813
            + T ++   PT T  ++ +    + L    +S  +    + T++A            N T
Sbjct: 1660 KATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPT 1719

Query: 1814 YGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTP-----SKPSSTPSKPTPGTK 1868
               T      +   +    ++S   T +   + + ST  P     S  S TP+  + GT+
Sbjct: 1720 STGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTR 1779

Query: 1869 PP 1870
             P
Sbjct: 1780 TP 1781



 Score =  180 bits (456), Expect = 2e-44
 Identities = 134/462 (29%), Positives = 213/462 (46%), Gaps = 58/462 (12%)

Query: 656  IGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDG-LMDD--GR 712
            +GQ C A +++ +C +      S P+  SC +         C  GC CP+G +++D    
Sbjct: 299  VGQ-CPANQVYQECGSACVKTCSNPQH-SCSS--------SCTFGCFCPEGTVLNDLSNN 348

Query: 713  GGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITF 772
              CV   +CPCV +  +Y+ G      C TC C  GRWVCT+  C G CS+ G     TF
Sbjct: 349  HTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTF 408

Query: 773  DGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKL 832
            D + Y F G C+Y+ +Q    Q    G+   + +    G +    S    +++ R +  +
Sbjct: 409  DARPYRFHGTCTYILLQS--PQLPEDGALMAVYDK--SGVSHSETSLVAVVYLSRQDKIV 464

Query: 833  EDKHRVVIQRDEGHHVAYTTREV------GQYLVVESSTGIIVIWDKRT--TVFIKLAPS 884
              +  VV    E   + Y TR +        +L + +S G+ ++   R     ++ + P 
Sbjct: 465  ISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQ 524

Query: 885  YKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCP-DVSTNPEPCSLNPH 943
            ++G   GLCGNF+  + +DFTT   +   +   F +SW+ A  CP  +    +PCS++  
Sbjct: 525  FRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWR-AGNCPAALERETDPCSMSQL 583

Query: 944  RRSWAEKQCSIL--KSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECF---CSAVAS 998
             +  AE  CS+L    +VF  CH+ V+P PFY+ CV+ +C+ +     E F   C+A+  
Sbjct: 584  NKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYE-----ETFPHICAALGD 638

Query: 999  YAQECTKEGACVF-WRTP-DLCPIFCD-----YYNPPHECEWHYEPCGNRSFETCRTING 1051
            Y   C+  G  ++ WR+  D C I C       YN    CE       +R+ E C     
Sbjct: 639  YVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYN-SQACERTCLSLSDRATE-CH---- 692

Query: 1052 IHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVE 1093
             HS + V   +GC   CP     Y     +CV   +C C +E
Sbjct: 693  -HSAVPV---DGC--NCPDG--TYLNQKGECVRKAQCPCILE 726



 Score =  167 bits (422), Expect = 2e-40
 Identities = 103/312 (33%), Positives = 162/312 (51%), Gaps = 26/312 (8%)

Query: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILL 96
           CSTWG  H+ TFD  V+ F G C+Y FA+ C+ ++  F+V L+RGP        +  I++
Sbjct: 45  CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGP-----DGSISRIIV 99

Query: 97  TIKDDTIYLTRH-LAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSR---AGLTLMWNREDA 152
            +    + ++   ++V +  V+S P+ S GL I       ++ ++     L ++W  +  
Sbjct: 100 ELGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSH 159

Query: 153 LMLELDTKFRNHTCGLCGDYNGLQSYSEFLS-DGVLFSPLEFGNMQKINQPDVVCEDPEE 211
           LM+ ++ K+    CGLCG+++G +  +EF+S +G    P +F  +QK++ P  +C   + 
Sbjct: 160 LMVLVERKYMGQMCGLCGNFDG-KVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDI 218

Query: 212 EVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRC--PGGDTCVCSTVA 269
                  ++H   C +LLT  A  +C   V  EP++ +CQ D      PG     C+T++
Sbjct: 219 PSTHVRQAQHARICTQLLTLVA-PECS--VSKEPFVLSCQADVAAAPQPGPQNSSCATLS 275

Query: 270 EFSRQCSHAGGRPGNWRTATSAVSPGASKT--CPGNLVYLESGSPCMDTCSHLEVSSLCE 327
           E+SRQCS  G     WR      SPG      CP N VY E GS C+ TCS+ + S  C 
Sbjct: 276 EYSRQCSMVGQPVRRWR------SPGLCSVGQCPANQVYQECGSACVKTCSNPQHS--CS 327

Query: 328 EHRMDGCFCPEG 339
                GCFCPEG
Sbjct: 328 SSCTFGCFCPEG 339



 Score =  142 bits (357), Expect = 6e-33
 Identities = 145/472 (30%), Positives = 186/472 (39%), Gaps = 54/472 (11%)

Query: 1416 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQ-TPTT 1474
            P   PT  Q PTT  + TT +    PT       T T I   S+  P+P+   T  +PT 
Sbjct: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251

Query: 1475 TPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPT 1534
            TP+   T  +  PT +  + P PT   T    +  P PT T   T+T  T T   T    
Sbjct: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLP-PTATLRSTATKPTVTQATTRATA 1310

Query: 1535 PTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITT 1594
             T +   T T  STT T    PTP  + T  T P +T   + P  T T T  P     +T
Sbjct: 1311 STASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQEL-PGTTATQTTGPRPTPAST 1369

Query: 1595 TTTMTPTPTPTSTKSTTVTPITTTTTVTATPTP-TGTQTPTMIPISTTTTVTPTPTPTTG 1653
            T   TP P           P  T TT T T T  T  QTP        TT +P   PT G
Sbjct: 1370 TGPTTPQP------GQPTRPTATETTQTRTTTEYTTPQTP-------HTTHSP---PTAG 1413

Query: 1654 STGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSP------LTESTTLLSTLPPAIEM 1707
            S  P T   TA     TT+ P P  S P+T+  T  P      +T ST  + T   A   
Sbjct: 1414 SPVPSTGPVTATSFHATTTYPTP--SHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMA 1471

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA----PTPSTVQTTT 1763
            TS +  S PT   T     TL    ST T+PP TPT   T+ + S+     TP+++ + T
Sbjct: 1472 TSASNHSAPTG--TIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHT 1529

Query: 1764 TSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEE-----------VYNG 1812
            +S   P  TP S      TT + P P+S      +  T  A                 + 
Sbjct: 1530 SSTHHPEVTPTS------TTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSS 1583

Query: 1813 TYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPT 1864
             +  T      S   T  +   S P T  PT  P  ST   +  + T   PT
Sbjct: 1584 PFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPT 1635



 Score =  123 bits (308), Expect = 3e-27
 Identities = 127/424 (29%), Positives = 177/424 (41%), Gaps = 69/424 (16%)

Query: 1485 PTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQ-TPTP 1543
            P   PT  Q PT   + TT +    PT     T TST I   ++  P+P+   T  +PT 
Sbjct: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251

Query: 1544 TPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPT 1603
            TP+   T  +  PT +  + P  T     T VTP  T   +  P T  + +T T  PT T
Sbjct: 1252 TPLLPATLTSSKPTASSGEPPRPT-----TAVTPQAT---SGLPPTATLRSTAT-KPTVT 1302

Query: 1604 PTSTKST--TVTPITTTTTVTAT------PTPTGTQTPTMIPIST-----------TTTV 1644
              +T++T  T +P TT+T  + T      PTP  + T   +P ST           TT  
Sbjct: 1303 QATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGP 1362

Query: 1645 TPTPTPTTGSTGPPTHTSTAPIA-ELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP- 1702
             PTP  TTG T P     T P A E T +    E +TPQT  +T SP T  + + ST P 
Sbjct: 1363 RPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPV 1422

Query: 1703 PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTT 1762
             A    +T    TP+ P TT   H   PP ST+   P T T  T       PT + + T+
Sbjct: 1423 TATSFHATTTYPTPSHPETTLPTHV--PPFSTSLVTPSTHTVIT-------PTHAQMATS 1473

Query: 1763 TTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVN 1822
             ++   PT T +  P+ ++ TG                T+ AP   +   T G +    +
Sbjct: 1474 ASNHSAPTGT-IPPPTTLKATG---------------STHTAP--PITPTTSGTSQAHSS 1515

Query: 1823 CSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSK--------PTPGTKPPECPD 1874
             S + T    +    ST  P  TP+ +T     P+ST ++         T    PP    
Sbjct: 1516 FSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTT 1575

Query: 1875 FDPP 1878
              PP
Sbjct: 1576 HSPP 1579



 Score =  104 bits (260), Expect = 1e-21
 Identities = 120/507 (23%), Positives = 183/507 (36%), Gaps = 70/507 (13%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C    C  +C+  G     TFD   Y + G CTY+L++  SP +   G  +  Y      
Sbjct: 388  CTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQ--SPQLPEDGALMAVYDKSGVS 445

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
                    +V    Q+ ++     +     V  N +A  LPYK   + V++    ++   
Sbjct: 446  HSETSLVAVVYLSRQDKIV-----ISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMA 500

Query: 2052 PELG--VLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAAD 2109
               G  ++V    +  +      +F   T+G CG     T+DD     G          D
Sbjct: 501  TSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVD 560

Query: 2110 QWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIK-DSLFAQCHALV 2168
             W        +CP +      P         +  +K C  +    L++  ++F +CHA V
Sbjct: 561  SWRAG-----NCPAALERETDPC------SMSQLNKVCAETHCSMLLRTGTVFERCHATV 609

Query: 2169 PPQHYYDACVFDSC-FMPGSSLECASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHR 2226
             P  +Y  CV+ +C +       CA+L  Y   C+ + + L  WR+     C + C  + 
Sbjct: 610  NPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDN-CTIPCTGNT 668

Query: 2227 EYQACGPAEEPTCKSSSSQ----QNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCV--GP 2280
             +     A E TC S S +     ++ V V+GC CP+GT     G  V    C C+  G 
Sbjct: 669  TFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGY 728

Query: 2281 DNVPREFGEHFEFDCKNCVCLEGGSGIICQP-------------KRCSQ----KPVTHCV 2323
              +  E  +    +   C C+ G      +P             K CSQ    K    C 
Sbjct: 729  KFILAE--QSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACA 786

Query: 2324 EDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESK 2383
                 LAT V    T C    C C   L +     C          VP   CP   CE  
Sbjct: 787  PTCQMLATGVACVPTKCE-PGCVCAEGLYENADGQC----------VPPEECP---CEFS 832

Query: 2384 GVCVHGNAEYQPGSPVYSSKCQDCVCT 2410
            GV   G AE         + C+ C C+
Sbjct: 833  GVSYPGGAELH-------TDCRTCSCS 852



 Score =  104 bits (259), Expect = 1e-21
 Identities = 104/373 (27%), Positives = 159/373 (42%), Gaps = 49/373 (13%)

Query: 759  GTCSIYGSGHYITFDGKYYDFDGHCSYV-------AVQDYCGQNSSLGSFSIITENVPCG 811
            G CS +G+GH+ TFD   YDF G C+Y+       A   +  Q       SI    V  G
Sbjct: 43   GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELG 102

Query: 812  TTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIW 871
             + VT S+AI        + L      +     G  V    R V + L +E    + V+W
Sbjct: 103  ASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSV----RLVAKQLELE----LEVVW 154

Query: 872  DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDV 931
               + + + +   Y G +CGLCGNFD +  N+F       VS E  F    K A     +
Sbjct: 155  GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEF-------VSEEGKFLEPHKFA-ALQKL 206

Query: 932  STNPEPCSL----NPH-RRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTG 986
                E C+     + H R++   + C+ L + V   C   V  +PF  +C  D  +    
Sbjct: 207  DDPGEICTFQDIPSTHVRQAQHARICTQLLTLVAPEC--SVSKEPFVLSCQADVAAAPQP 264

Query: 987  GDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWH--YEPCGNRSF 1043
            G     C+ ++ Y+++C+  G  V  WR+P LC +         +C  +  Y+ CG+   
Sbjct: 265  GPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSV--------GQCPANQVYQECGSACV 316

Query: 1044 ETCRTINGIHSNISVSYLEGCYPRCPKDRPIYE-EDLKKCVTADKCGCYVEDTHYPPGAS 1102
            +TC   N  HS  S S   GC+  CP+   + +  +   CV   +C C +    Y PG  
Sbjct: 317  KTCS--NPQHS-CSSSCTFGCF--CPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGE- 370

Query: 1103 VPTEETCKSCVCT 1115
              T   C++C CT
Sbjct: 371  -VTIAACQTCRCT 382



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 85/298 (28%), Positives = 129/298 (43%), Gaps = 33/298 (11%)

Query: 15   LSLAGGSELQTEGRTRN------------HGHNVCSTWGNFHYKTFDGDVFRFPGLCDYN 62
            +S  GG+EL T+ RT +            H  + C+ +G  H  TFDG  F F G C+Y 
Sbjct: 834  VSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYI 893

Query: 63   FASDCRG------SYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAV 116
             A+D  G      ++K    ++  G         ++  L  +    +   R+  V     
Sbjct: 894  LATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLS--VVLADRNYTVTGEEP 951

Query: 117  VSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNG-L 175
                  +PG L    D    +  R  LTL+WNR   +++ +    ++  CGLCG++NG +
Sbjct: 952  HVQLGVTPGALSLVVDI--SIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNM 1009

Query: 176  QSYSEFLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEVAPASCSE-HRAECER---LLTA 231
            +   E  S  V  S LE  N  K      +C D      P S +   R+  ER   ++ +
Sbjct: 1010 KDDFETRSRYVASSELELVNSWK---ESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINS 1066

Query: 232  EAFADCQDLVPLEPYLRACQQDRCRC-PGGD-TCVCSTVAEFSRQCSHAGGRPGNWRT 287
            + FA C   V   PY  AC +D C C  GGD  C+C  VA +++ C   G    +WRT
Sbjct: 1067 QTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCV-DWRT 1123



 Score = 90.9 bits (224), Expect = 2e-17
 Identities = 112/490 (22%), Positives = 177/490 (36%), Gaps = 72/490 (14%)

Query: 1820 FVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPR 1879
            F +CS S   +F   +C  T     T     PT  +P    ++        +C    PP 
Sbjct: 770  FKSCSQSSENKF-GAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCV---PPE 825

Query: 1880 QENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDC 1939
            +       C C  +   Y    E+   +C      +CS G           C     C  
Sbjct: 826  E-------CPCEFSGVSYPGGAEL-HTDCRTC---SCSRGRW--------ACQQGTHCPS 866

Query: 1940 YCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE---ISPSVDNFGVYIDNYHCDPNDKVSCP 1996
             CT +G+ H +TFDG  + + GNC Y+L  +   ++ S   F +  +N  C  N  V+C 
Sbjct: 867  TCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG-NSGVTCS 925

Query: 1997 RTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELG- 2055
            R +             + +  + V +      V        L V    ++ VVDI   G 
Sbjct: 926  RAI------------KIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVDISIPGR 973

Query: 2056 ---VLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWL 2112
                L+    ++  +R+      +   G CG       DD    S  + S+     + W 
Sbjct: 974  YNLTLIWNRHMTILIRIA-RASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSW- 1031

Query: 2113 VNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQH 2172
                  P C   S  T   ++           +       C +I    FA CH+ V    
Sbjct: 1032 ---KESPLCGDVSFVTDPCSLNA--------FRRSWAERKCSVINSQTFATCHSKVYHLP 1080

Query: 2173 YYDACVFDSCFM-PGSSLECA--SLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQ 2229
            YY+ACV D+C    G   EC   ++ AYA  C  + +C+DWR  T   C + C  +  + 
Sbjct: 1081 YYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWR--TPAFCPIYCGFYNTHT 1138

Query: 2230 ACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGE 2289
              G  E       + + N T   + C CP    +  PG +  ++ C     D    E+ +
Sbjct: 1139 QDGHGE----YQYTQEANCTWHYQPCLCPSQPQS-VPGSN--IEGCYNCSQD----EYFD 1187

Query: 2290 HFEFDCKNCV 2299
            H E  C  C+
Sbjct: 1188 HEEGVCVPCM 1197



 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 82/311 (26%), Positives = 135/311 (43%), Gaps = 42/311 (13%)

Query: 359 VVFKSDGSVLLNELQV-NLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTL 417
           VV  S+  + + ++ V +LP+ +    +        +V+  + + L+V   P   L V +
Sbjct: 105 VVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLV 164

Query: 418 DQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDP--- 474
           ++   GQ+ GLCGNF+G   ++F +  G        F    K  +     L  LDDP   
Sbjct: 165 ERKYMGQMCGLCGNFDGKVTNEFVSEEG-------KFLEPHKFAA-----LQKLDDPGEI 212

Query: 475 C------SLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNC--QNNE 526
           C      S ++  A +A   C+ L     P   C  + +P  +   C+ D         +
Sbjct: 213 CTFQDIPSTHVRQAQHA-RICTQLLTLVAP--ECSVSKEP--FVLSCQADVAAAPQPGPQ 267

Query: 527 DCLCAALSSYARACTAKGVMLWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEA 585
           +  CA LS Y+R C+  G  +  WR   +C+  VG CP +QV+    + C +TC +   +
Sbjct: 268 NSSCATLSEYSRQCSMVGQPVRRWRSPGLCS--VGQCPANQVYQECGSACVKTCSNPQHS 325

Query: 586 -DSHCLEGFAPVDGCGCPDHTFLDEKGR---CVPLAKCSCYHRGLYLEAGDVVVRQEERC 641
             S C        GC CP+ T L++      CVP+ +C C   G     G+V +   + C
Sbjct: 326 CSSSC------TFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTC 379

Query: 642 VCRDGRLHCRQ 652
            C  GR  C +
Sbjct: 380 RCTLGRWVCTE 390



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 89/327 (27%), Positives = 144/327 (44%), Gaps = 36/327 (11%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVT------PTPT 1350
            V  PTT+  T + +  P    TT+  + T +  ST + + + I++++ +       P  +
Sbjct: 2046 VPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSS 2105

Query: 1351 PTGTQTP----TTTPITTTTTVTPT--PTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTP 1403
            P  TQ P     TTP++TT  ++ +  P+P+   T ++  P + ++  T +P+   + + 
Sbjct: 2106 PITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSF 2165

Query: 1404 TSTPITTTTTVTPTPTPTGTQTPTTTPITTT----------TTVTPTPTPTGTQAPTPTA 1453
             S P+ +TT  + + +   T  PTT  ++ +          TT+  T   T +   T +A
Sbjct: 2166 VSAPVHSTTLSSGSHSSLSTH-PTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSA 2224

Query: 1454 ITTTSTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTP- 1510
            +   STVT +PTP+     +T   P T  TT +    P  +   T +  T+ TT  PT  
Sbjct: 2225 LLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSG 2284

Query: 1511 ----TPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPT---GTQT 1563
                T   T  PTS P+T  TT  P PT + T T   T   T    TP   P    GT T
Sbjct: 2285 FVSLTSGVTGIPTS-PVTNLTTRHPGPTLSPT-TRFLTSSLTAHGSTPASAPVSSLGTPT 2342

Query: 1564 PTTTPITTTTTVTPTPTPTGTQTPTTV 1590
            PT+  + +        T  G     TV
Sbjct: 2343 PTSPGVCSVREQQEEITFKGCMANVTV 2369



 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 104/409 (25%), Positives = 162/409 (39%), Gaps = 64/409 (15%)

Query: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000
            C+ WG  H+ TFD   Y + G C Y+       +   F V +      P+  +S    +I
Sbjct: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRR---GPDGSIS---RII 98

Query: 2001 VRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEV--YQSGINYVVDIPELGVLV 2058
            V      V +    +    + V      ++LPY   GL++  +   +  V    EL + V
Sbjct: 99   VELGASVVTVSEAIISVKDIGV------ISLPYTSNGLQITPFGQSVRLVAKQLELELEV 152

Query: 2059 SYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSK 2118
             +   S  + L   ++     G CG      +++ +   G+ +   + AA Q L +DP +
Sbjct: 153  VWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKL-DDPGE 211

Query: 2119 PHCPHSS--STTKRPAVTVPGGGKTTPHKDCTP-----SPLCQLIKDSLFAQCHALVPPQ 2171
              C      ST  R A            + CT      +P C + K+     C A V   
Sbjct: 212  -ICTFQDIPSTHVRQAQHA---------RICTQLLTLVAPECSVSKEPFVLSCQADVA-- 259

Query: 2172 HYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNICL-DWRNHTHGACLV-ECPSHREY 2228
                     +   PG  +  CA+L  Y+  C+     +  WR  + G C V +CP+++ Y
Sbjct: 260  ---------AAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWR--SPGLCSVGQCPANQVY 308

Query: 2229 QACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGT-MNYAPGFDVCVKT--CGCV--GPDNV 2283
            Q CG A   TC S+     ++    GCFCPEGT +N       CV    C CV  G    
Sbjct: 309  QECGSACVKTC-SNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYA 367

Query: 2284 PREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHC-VEDGTYLAT 2331
            P   GE     C+ C C  G    +C  + C      HC +E G+++ T
Sbjct: 368  P---GEVTIAACQTCRCTLG--RWVCTERPCP----GHCSLEGGSFVTT 407



 Score = 72.4 bits (176), Expect = 6e-12
 Identities = 76/325 (23%), Positives = 124/325 (38%), Gaps = 31/325 (9%)

Query: 33  GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCR----GSYKEFAVHLKRGPGQAEAP 88
           GH  CS  G     TFD   +RF G C Y      +    G+    AV+ K G   +E  
Sbjct: 395 GH--CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGAL--MAVYDKSGVSHSETS 450

Query: 89  AGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLI-EKSDAYTKVYSRAGLTLMW 147
             V  + L+ +D  +     +   NG     P+ +  + +  ++  + ++ +  GL L+ 
Sbjct: 451 L-VAVVYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVV 509

Query: 148 NREDALM--LELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVL--FSPLEFGNMQKINQPD 203
                    + +  +FR  T GLCG++NG  +     S G+    + L   + +  N P 
Sbjct: 510 QLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPA 569

Query: 204 VVCEDPEEEVAPASCSEHRAECER------LLTAEAFADCQDLVPLEPYLRACQQDRCRC 257
            +    E E  P S S+    C        L T   F  C   V   P+ + C    C  
Sbjct: 570 AL----ERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNY 625

Query: 258 PGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTC 317
                 +C+ + ++   CS  G     WR++        +  C GN  +  +   C  TC
Sbjct: 626 EETFPHICAALGDYVHACSLRGVLLWGWRSSVD----NCTIPCTGNTTFSYNSQACERTC 681

Query: 318 SHLEVSSLCEEHR---MDGCFCPEG 339
             L   +    H    +DGC CP+G
Sbjct: 682 LSLSDRATECHHSAVPVDGCNCPDG 706



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 71/261 (27%), Positives = 100/261 (38%), Gaps = 50/261 (19%)

Query: 1629 GTQTPTMIPISTTTTVTPTPTPTTGS----TGPPTHTSTAPIAELTTSNPPPESSTPQTS 1684
            G   P M P +     TP   PTTGS      P T TST  I  L+++ P P S+    S
Sbjct: 1191 GVCVPCMPPTTPQPPTTPQ-LPTTGSRPTQVWPMTGTSTT-IGLLSSTGPSPSSNHTPAS 1248

Query: 1685 RSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR 1744
              T +PL  +T  L++  P         P+T   P  TSG    +   ST T P  T T+
Sbjct: 1249 -PTQTPLLPAT--LTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKP--TVTQ 1303

Query: 1745 GTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRP-YPSSVLICCVLNDTYY 1803
             TT  ++S  +P+T  T+T  + T T   L TP+   T+G  P  P S            
Sbjct: 1304 ATTRATASTASPAT--TSTAQSTTRTTMTLPTPA---TSGTSPTLPKST----------- 1347

Query: 1804 APGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKP 1863
               +E+   T   T                    + P PTP  +    TP     T    
Sbjct: 1348 --NQELPGTTATQT--------------------TGPRPTPASTTGPTTPQPGQPTRPTA 1385

Query: 1864 TPGTKPPECPDFDPPRQENET 1884
            T  T+     ++  P+  + T
Sbjct: 1386 TETTQTRTTTEYTTPQTPHTT 1406



 Score = 55.5 bits (132), Expect = 7e-07
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 4/99 (4%)

Query: 2526 TPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEE 2585
            TP   +   CS      E+++ GC   V +  C G+C +   ++   Q +D  CSCC+  
Sbjct: 2340 TPTPTSPGVCSVREQQEEITFKGCMANVTVTRCEGACISAASFNIITQQVDARCSCCRPL 2399

Query: 2586 KTSQREVVLSCPN----GGSLTHTYTHIESCQCQDTVCG 2620
             + ++++ L CP+    G  L  T      C C    CG
Sbjct: 2400 HSYEQQLELPCPDPSTPGRRLVLTLQVFSHCVCSSVACG 2438


>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
            sapiens]
          Length = 2134

 Score =  666 bits (1719), Expect = 0.0
 Identities = 462/1576 (29%), Positives = 696/1576 (44%), Gaps = 155/1576 (9%)

Query: 38   STWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQ------------- 84
            STW    YK+F+G +F F   C Y F   C  S  +F + +KR   +             
Sbjct: 609  STWSKGAYKSFNGRIFFFESSCPYTFCRHCIESGGDFNIEIKRNNDRQDINEHIANSKIP 668

Query: 85   AEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
             + P  V       +D   +  +        ++ T     G +   S+ Y  +       
Sbjct: 669  GDCPNAVGKSYEVCEDGIQHCNK--------IIGTYFEKCGKVAALSNDYKMI------- 713

Query: 145  LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDV 204
                    +     T+ +  TC    + + L +     SDG    P  F + +  +  DV
Sbjct: 714  -------CIDEYCQTRDKTSTCDTYSELSRLCA-----SDG----PGTFESWR--SDSDV 755

Query: 205  VCED---PEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGD 261
            VCE    PE+ +       + A C  +   +           E YL     ++ +C    
Sbjct: 756  VCETQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKA 815

Query: 262  TCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMD------ 315
             C C +     +      G  G+  T   A        CPG      S     D      
Sbjct: 816  ECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSSLTTFDGVKYNF 875

Query: 316  --TCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNV--VVFKSDGSVLLNE 371
               C  L V +      ++   CP G       +V LL +    V   VF SDG+V  ++
Sbjct: 876  PGNCHFLAVHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDK 935

Query: 372  LQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGN 431
            ++    + +    +F  SS ++ V     V+LQ+Q+ PVMQL+V++         GLCG+
Sbjct: 936  IRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGS 995

Query: 432  FNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCS-LNIESANYAEHWCS 490
            +N    DDF ++  ++E T   FAN+W+  S          +P S ++IE   +AE  C 
Sbjct: 996  YNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG------NPSSCISIEKEKFAERHCG 1049

Query: 491  LLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGW 550
            +L  +  P   CH  V+P  Y++ CK  TC C+N++DCLC  L +Y +AC  K   + GW
Sbjct: 1050 ILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGW 1109

Query: 551  REHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEK 610
            R  +C     SCP+  VF YN+  C  +CRSLSE D  C     PVDGC CPD  + + +
Sbjct: 1110 RTGLCEH---SCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNE 1166

Query: 611  GRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCR-QIRLIGQSCTAPKIHMDC 669
            G CV  ++C CY     ++ G ++   + +CVCRDG L C+  I L  Q+C+    ++DC
Sbjct: 1167 GNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDC 1226

Query: 670  SNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDL 729
            S+  A   +  R  S + +     +  C  GC CP+G++ + +G CV   +CPC      
Sbjct: 1227 SDPKAQRRTN-RTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGRE 1285

Query: 730  YSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQ 789
            Y  G+   V CN CTC +G W CTQ  C   C IYG GH  TFDGK Y FDG C Y  ++
Sbjct: 1286 YDEGSVTSVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLE 1345

Query: 790  DYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHV- 848
            DYCG  +  G+F I+TE+VPC   G+TCS+ I +      + L+D     ++  E     
Sbjct: 1346 DYCGHEN--GTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCE 1403

Query: 849  ----AYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDF 904
                AY+   VG YL+++   GIIVIWDK T + + L P++ G VCGLCGN +    +DF
Sbjct: 1404 LNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDF 1463

Query: 905  TTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICH 964
            TTR   V S  L+FGNSWK +  C D      PC  NP+ ++WA ++C IL+ S F  CH
Sbjct: 1464 TTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCH 1523

Query: 965  SKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDY 1024
            +KVDP  +++ C+ ++C+CD  G    FC+AVA YA+ C+  G CV WR P+LCP++CDY
Sbjct: 1524 NKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDY 1583

Query: 1025 YNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVT 1084
            YN P EC WHYEPCG  + +TC+  + +      S LEGCY +CP   P  +E+  KCV+
Sbjct: 1584 YNAPGECRWHYEPCGTVTAKTCK--DQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVS 1641

Query: 1085 ADKCGCYVEDTHYPPGASVPTEETC-KSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEI 1143
              +C C+  D   P G  +  E+ C ++C C  + Q+ C   E    N T       + +
Sbjct: 1642 LSECSCFYNDV-IPAGGVI--EDNCGRTCYCI-AGQLEC--SETAPTNST-------FAV 1688

Query: 1144 CGPNGT--VEKHFNICSITTRPSTLTTFTTITLPTTPTTFTTT-------TTTTTPTSST 1194
                 T  +     I  +T  PST  +   IT  ++ TT TT        TT  T TS  
Sbjct: 1689 STTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLTEPFTTGITETSVP 1748

Query: 1195 VLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQ 1254
            ++ST+       +       P+     G   T  GV  A       +        E+ G 
Sbjct: 1749 IISTSGN-----AGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTS------ERAGT 1797

Query: 1255 KVQLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPT 1314
                    +VG      +  PG  +      +    V        P    T++  + +  
Sbjct: 1798 PRVSGATPAVGGGSTPGEAGPGATV------SGSTGVSAGSITASPGASATSSESSKSG- 1850

Query: 1315 PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1374
              TT  +V      TS+++T+   ++  T  +      G+   + + IT  T+ T +  P
Sbjct: 1851 --TTGPSVGGKTGATSSEATSSEGMSGVTGQS-----LGSTAGSDSEITAKTSFTGSSPP 1903

Query: 1375 TGTQTP-----------TTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTV----TPTPT 1419
                 P           TT      TT       +G    T   +  TT+     T   +
Sbjct: 1904 GKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTS 1963

Query: 1420 PTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTT----- 1474
             TG   P  T ++ T  V+P  TP    + TP      +T       +G  + T      
Sbjct: 1964 GTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAF 2023

Query: 1475 ---TPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTP 1531
               TP  +  + T +P    T   + TA+T + +   TP   GT    ++    T+  + 
Sbjct: 2024 LRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTP---GTPGGATSGGKITSGWSS 2080

Query: 1532 TPTPTGTQTPTPTPIS 1547
            + T TG+   TP  IS
Sbjct: 2081 SGTSTGSSN-TPGEIS 2095



 Score =  110 bits (274), Expect = 2e-23
 Identities = 98/398 (24%), Positives = 156/398 (39%), Gaps = 59/398 (14%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDN-FGVYIDNYHCDPN 1990
            C   EC   C  +G+ H  TFDG  YS+ G C Y  +E+     +  F +  ++  C   
Sbjct: 1308 CTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCC-E 1366

Query: 1991 DKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVY-----QSGI 2045
            D ++C R +IV  + Q ++++   +  ++       +  A  Y  + + +Y     Q+GI
Sbjct: 1367 DGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGI 1426

Query: 2046 NYVVDI-PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNC 2104
              + D    L V++  N            +     G CG       DD       + S  
Sbjct: 1427 IVIWDKNTRLSVILDPN------------WNGKVCGLCGNNNGDLKDDFTTRYSSVASGA 1474

Query: 2105 EAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQC 2164
                + W            S   +   A T P    + P+        C++++DS F  C
Sbjct: 1475 LEFGNSWKT----------SQECSDTVAQTFPCD--SNPYCKAWAVRKCEILRDSTFRDC 1522

Query: 2165 HALVPPQHYYDACVFDSCF--MPGSSLE-CASLQAYAALCAQQNICLDWRNHTHGACLVE 2221
            H  V P  Y+D C+ ++C   M G  L  C ++  YA  C+   +C+ WR      C V 
Sbjct: 1523 HNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRK--PNLCPVY 1580

Query: 2222 CPSHR-------EYQACGPAEEPTCKSSSSQQNNTVLVEGCF--CPEGTMNYAPGFD--- 2269
            C  +         Y+ CG     TCK     Q  + L+EGC+  CP+     AP  D   
Sbjct: 1581 CDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDS----APYLDENT 1636

Query: 2270 ---VCVKTCGCVGPDNVPREFGEHFEFDC-KNCVCLEG 2303
               V +  C C   D +P   G   E +C + C C+ G
Sbjct: 1637 MKCVSLSECSCFYNDVIPA--GGVIEDNCGRTCYCIAG 1672



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 124/565 (21%), Positives = 214/565 (37%), Gaps = 93/565 (16%)

Query: 1903 IVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWG-------------DPHY 1949
            ++K EC   P  +     QP  V +  G C   +C C    W                  
Sbjct: 812  VLKAEC---PCESSGTVYQPGEVRE--GPCGS-QCTCQDAKWSCTEALCPGRCKVEGSSL 865

Query: 1950 VTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVL 2009
             TFDG+ Y++ GNC ++ V       +++ + ++   C      +C  ++ +   +   +
Sbjct: 866  TTFDGVKYNFPGNCHFLAVHN-----EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPV 920

Query: 2010 IKTVHMMPMQV-QVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN---GLSF 2065
             K V      V   ++  Q     Y    ++++ +  +Y+       V +       +  
Sbjct: 921  DKYVFNSDGTVTNDKIRNQGY---YYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQL 977

Query: 2066 SVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSS 2125
             V +P ++F  +T G CG+  N   DD +     +    +A A+ W +       CP  +
Sbjct: 978  YVSMPPNQF-TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-----CPKGN 1031

Query: 2126 STTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSL--FAQCHALVPPQHYYDACVFDSCF 2183
             ++    +++         K+      C ++ DS    A CH +V P+ Y++ C   +C 
Sbjct: 1032 PSS---CISI--------EKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCT 1080

Query: 2184 MPGSS-LECASLQAYAALCAQ-QNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKS 2241
               S    C  L  Y   CA+ +   + WR    G C   CPS   ++    A   +C+S
Sbjct: 1081 CENSQDCLCTILGNYVKACAEKETYIVGWRT---GLCEHSCPSGLVFKYNVKACNSSCRS 1137

Query: 2242 SSSQQNNT----VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKN 2297
             S +  +     V V+GC CP+       G  V    C C   D V +  G+    D   
Sbjct: 1138 LSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQP-GKLIHIDDNK 1196

Query: 2298 CVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPAD---------TCCNITVCKCN 2348
            CVC +G   ++C      Q P+   +++ +  A  V+ +D         TC    +   +
Sbjct: 1197 CVCRDG--ILLC------QIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFD 1248

Query: 2349 TSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCV 2408
             +L  ++   CP G    SK +    C F    +   C  G  EY  GS V S  C +C 
Sbjct: 1249 ENLPCKRGCFCPEGMVRNSKGI----CVF---PNDCPCSFGGREYDEGS-VTSVGCNECT 1300

Query: 2409 CTDKVDNNTLLNVIACTHVPCNTSC 2433
            C        +    +CT   C T C
Sbjct: 1301 C--------IKGSWSCTQNECQTIC 1317



 Score = 90.1 bits (222), Expect = 3e-17
 Identities = 84/327 (25%), Positives = 128/327 (39%), Gaps = 21/327 (6%)

Query: 29   TRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASD-CRGSYKEFAVHLKRGPGQAEA 87
            T+N    +C  +G  H +TFDG  + F GLC Y+F  D C      F +  +  P   + 
Sbjct: 1309 TQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDG 1368

Query: 88   PAGVESILLTIKDDTIYLT--RHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTL 145
                  I++  +D  I L   +  AV +         +    I     Y  +  + G+ +
Sbjct: 1369 LTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIV 1428

Query: 146  MWNREDALMLELDTKFRNHTCGLCGDYNG-LQSYSEFLSDGVLFSPLEFGNMQKINQPDV 204
            +W++   L + LD  +    CGLCG+ NG L+         V    LEFGN  K +Q   
Sbjct: 1429 IWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE-- 1486

Query: 205  VCEDPEEEVAPASCSEH-----RAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRC-- 257
             C D   +  P   + +       +CE +L    F DC + V    Y   C ++ C C  
Sbjct: 1487 -CSDTVAQTFPCDSNPYCKAWAVRKCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDM 1544

Query: 258  PGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNL--VYLESGSPCMD 315
             G     C+ VA ++  CS A G   +WR              PG     Y   G+    
Sbjct: 1545 EGKYLGFCTAVAMYAEACS-AVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAK 1603

Query: 316  TCSHLEVSSLCEEHRMDGCF--CPEGA 340
            TC    V        ++GC+  CP+ A
Sbjct: 1604 TCKDQLVGQKFSS-LLEGCYAKCPDSA 1629



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 113/443 (25%), Positives = 164/443 (37%), Gaps = 44/443 (9%)

Query: 1324 PTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1383
            PT +  +  +TT T I +T       T  G  T  + P  TT++   T T  G   P T 
Sbjct: 1681 PTNSTFAVSTTTATTILSTGAAITLVTG-GPSTAASIPAITTSSSETTGTTLG---PLTE 1736

Query: 1384 PITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1443
            P TT  T T  P        TS     T  V+PT T       TT  +   TT   +   
Sbjct: 1737 PFTTGITETSVPI-----ISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASEN- 1790

Query: 1444 TGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTT 1503
            T  +A TP     T  V    TP G   P  T ++ +T V+      G+ T +P A  T+
Sbjct: 1791 TSERAGTPRVSGATPAVGGGSTP-GEAGPGAT-VSGSTGVS-----AGSITASPGASATS 1843

Query: 1504 TTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQT 1563
            +  + + T TG      T  T++   +       T     +   + + +T   + TG+  
Sbjct: 1844 SESSKSGT-TGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTGSSP 1902

Query: 1564 PTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTA 1623
            P    +T  +  +P     GT     V  T       +    ST+ +     +  +  TA
Sbjct: 1903 P--GKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTA 1960

Query: 1624 TPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIA----------ELTTSN 1673
              + TG   P    +S T  V+P  TP    +  P        +           LT  N
Sbjct: 1961 GTSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLN 2020

Query: 1674 PPPESSTPQTS--RSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPP 1731
            P     TP  S   +TSSP+++ T   S     I  +    P TP     TSGG   S  
Sbjct: 2021 PAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGG--ATSGGKITS-- 2076

Query: 1732 PSTTTSPPGTPTRGTTTGSSSAP 1754
                    G  + GT+TGSS+ P
Sbjct: 2077 --------GWSSSGTSTGSSNTP 2091



 Score = 63.5 bits (153), Expect = 3e-09
 Identities = 104/413 (25%), Positives = 152/413 (36%), Gaps = 62/413 (15%)

Query: 1485 PTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPT 1544
            PT +     T T T I +T       T  G  T  S P  TT++   T T  G   P   
Sbjct: 1681 PTNSTFAVSTTTATTILSTGAAITLVTG-GPSTAASIPAITTSSSETTGTTLG---PLTE 1736

Query: 1545 PISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP 1604
            P +T  T T  P  +     T+     T  V+PT T       TT  +   TT   +   
Sbjct: 1737 PFTTGITETSVPIIS-----TSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASEN- 1790

Query: 1605 TSTKSTTVTPITTTTTVTATPTP------------TGTQTPTMIPISTTTTVTPTPTPTT 1652
            TS ++ T      T  V    TP            TG    + I  S   + T + +  +
Sbjct: 1791 TSERAGTPRVSGATPAVGGGSTPGEAGPGATVSGSTGVSAGS-ITASPGASATSSESSKS 1849

Query: 1653 GSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTS---SPLTESTTLLSTLPPAIEMTS 1709
            G+TGP     T   +   TS+      T Q+  ST+   S +T  T+   + PP  ++T 
Sbjct: 1850 GTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTGSSPPG-KLTR 1908

Query: 1710 TAPPSTP-----------TAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPST 1758
             +P S              A T  +G +T     ST  S   T + G+   + ++ T  T
Sbjct: 1909 PSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDT 1968

Query: 1759 VQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGE-EVYNGTYGDT 1817
                T  + TP  +P +TP           P S             PGE ++ N ++G +
Sbjct: 1969 GPGNTAVSGTPVVSPGATPGA---------PGS-----------STPGEADIGNTSFGKS 2008

Query: 1818 CYFVNCSLSCTLEFYNWSCP--STPSPTPTP-SKSTPTPSKPSSTPSKPTPGT 1867
                + SL+     +    P  S  S T +P SK T   S  + T S   PGT
Sbjct: 2009 GKSGHDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGT 2061



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 5/112 (4%)

Query: 2153 CQLIKDSLFAQCHALVPPQHYYDA-CVFDSCFMPGSSLECASLQAYAALCAQQN--ICLD 2209
            C  I  + F +C  +    + Y   C+ + C     +  C +    + LCA         
Sbjct: 689  CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 748

Query: 2210 WRNHTHGACLVE-CPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEG 2260
            WR+ +   C  + CP    Y+ CGP+   TC + +  Q++   V GC CPEG
Sbjct: 749  WRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQDSE-CVSGCTCPEG 799



 Score = 40.8 bits (94), Expect = 0.018
 Identities = 34/123 (27%), Positives = 47/123 (38%), Gaps = 28/123 (22%)

Query: 2219 LVECPSHREYQACG-PAEEPTCKSSSSQQNNTVLVE------GCFCPEGTMNYAPGFDVC 2271
            L  C    EY  C  P  +     + S +N  V  E      GCFCPEG +  + G    
Sbjct: 1214 LQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGI--- 1270

Query: 2272 VKTCGCVGPDNVPREFGEHFEFD--------CKNCVCLEGGSGIICQPKRCSQKPVTHCV 2323
                 CV P++ P  FG   E+D        C  C C++G     C    C  + + H  
Sbjct: 1271 -----CVFPNDCPCSFGGR-EYDEGSVTSVGCNECTCIKGSWS--CTQNEC--QTICHIY 1320

Query: 2324 EDG 2326
             +G
Sbjct: 1321 GEG 1323


>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
            sapiens]
          Length = 2134

 Score =  663 bits (1711), Expect = 0.0
 Identities = 463/1580 (29%), Positives = 696/1580 (44%), Gaps = 163/1580 (10%)

Query: 38   STWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQ------------- 84
            STW    YK+F+G +F F   C Y F   C  S  +F + +KR   +             
Sbjct: 609  STWSKGAYKSFNGRIFFFESSCPYTFCRHCIESGGDFNIEIKRNNDRQDINEHIANSKIP 668

Query: 85   AEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
             + P  V       +D   +  +        ++ T     G +   S+ Y  +       
Sbjct: 669  GDCPNAVGKSYEVCEDGIQHCNK--------IIGTYFEKCGKVAALSNDYKMI------- 713

Query: 145  LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDV 204
                    +     T+ +  TC    + + L +     SDG    P  F + +  +  DV
Sbjct: 714  -------CIDEYCQTRDKTSTCDTYSELSRLCA-----SDG----PGTFESWR--SDSDV 755

Query: 205  VCED---PEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGD 261
            VC     PE+ +       + A C  +   +           E YL     ++ +C    
Sbjct: 756  VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKA 815

Query: 262  TCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMD------ 315
             C C +     +      G  G+  T   A        CPG      S     D      
Sbjct: 816  ECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSSLTTFDGVKYNF 875

Query: 316  --TCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNV--VVFKSDGSVLLNE 371
               C  L V +      ++   CP G       +V LL +    V   VF SDG+V  ++
Sbjct: 876  PGNCHFLAVHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDK 935

Query: 372  LQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGN 431
            ++    + +    +F  SS ++ V     V+LQ+Q+ PVMQL+V++         GLCG+
Sbjct: 936  IRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGS 995

Query: 432  FNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCS-LNIESANYAEHWCS 490
            +N    DDF ++  ++E T   FAN+W+  S          +P S ++IE   +AE  C 
Sbjct: 996  YNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG------NPSSCISIEKEKFAERHCG 1049

Query: 491  LLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGW 550
            +L  +  P   CH  V+P  Y++ CK  TC C+N++DCLC  L +Y +AC  K   + GW
Sbjct: 1050 ILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGW 1109

Query: 551  REHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEK 610
            R  +C     SCP+  VF YN+  C  +CRSLSE D  C     PVDGC CPD  + + +
Sbjct: 1110 RTGLCEH---SCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNE 1166

Query: 611  GRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCR-QIRLIGQSCTAPKIHMDC 669
            G CV  ++C CY     ++ G ++   + +CVCRDG L C+  I L  Q+C+    ++DC
Sbjct: 1167 GNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDC 1226

Query: 670  SNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDL 729
            S+  A   +  R  S + +     +  C  GC CP+G++ + +G CV   +CPC      
Sbjct: 1227 SDPKAQRRTN-RTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGRE 1285

Query: 730  YSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQ 789
            Y  G+   V CN CTC +G W CTQ  C   C IYG GH  TFDGK Y FDG C Y  ++
Sbjct: 1286 YDEGSVTSVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLE 1345

Query: 790  DYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHV- 848
            DYCG  +  G+F I+TE+VPC   G+TCS+ I +      + L+D     ++  E     
Sbjct: 1346 DYCGHEN--GTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCE 1403

Query: 849  ----AYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDF 904
                AY+   VG YL+++   GIIVIWDK T + + L P++ G VCGLCGN +    +DF
Sbjct: 1404 LNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDF 1463

Query: 905  TTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICH 964
            TTR   V S  L+FGNSWK +  C D      PC  NP+ ++WA ++C IL+ S F  CH
Sbjct: 1464 TTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCH 1523

Query: 965  SKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDY 1024
            +KVDP  +++ C+ ++C+CD  G    FC+AVA YA+ C+  G CV WR P+LCP++CDY
Sbjct: 1524 NKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDY 1583

Query: 1025 YNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVT 1084
            YN P EC WHYEPCG  + +TC+  + +      S LEGCY +CP   P  +E+  KCV+
Sbjct: 1584 YNAPGECRWHYEPCGTVTAKTCK--DQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVS 1641

Query: 1085 ADKCGCYVEDTHYPPGASVPTEETC-KSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEI 1143
              +C C+  D   P G  +  E+ C ++C C  + Q+ C   E    N T       + +
Sbjct: 1642 LSECSCFYNDV-IPAGGVI--EDNCGRTCYCI-AGQLEC--SETAPTNST-------FAV 1688

Query: 1144 CGPNGT--VEKHFNICSITTRPSTLTTFTTITLPTTPTTFTTT-------TTTTTPTSST 1194
                 T  +     I  +T  PST  +   IT  ++ TT TT        TT  T TS  
Sbjct: 1689 STTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLTEPFTTGITETSVP 1748

Query: 1195 VLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDGV----CGAPEDIECRSVKDPHLSLE 1250
            ++ST+       +       P+     G   T  GV     GA  +        P +S E
Sbjct: 1749 IISTSGN-----AGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERAGTPRVSGE 1803

Query: 1251 QLGQKVQLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTEN 1310
                        +VG      +  PG  +      +    V        P    T++  +
Sbjct: 1804 ----------TPAVGGGSTPGEAGPGATV------SGSTGVSAGSITASPGASATSSESS 1847

Query: 1311 PTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1370
             +    TT  +V      TS+++T+   ++  T  +      G+   + + IT  T+ T 
Sbjct: 1848 KSG---TTGPSVGGKTGATSSEATSSEGMSGVTGQS-----LGSTAGSDSEITAKTSFTG 1899

Query: 1371 TPTPTGTQTP-----------TTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTV----T 1415
            +  P     P           TT      TT       +G    T   +  TT+     T
Sbjct: 1900 SSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNT 1959

Query: 1416 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTT- 1474
               + TG   P  T ++ T  V+P  TP    + TP      +T       +G  + T  
Sbjct: 1960 AGTSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVL 2019

Query: 1475 -------TPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTT 1527
                   TP  +  + T +P    T   + TA+T + +   TP   GT    ++    T+
Sbjct: 2020 NPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTP---GTPGGATSGGKITS 2076

Query: 1528 TVTPTPTPTGTQTPTPTPIS 1547
              + + T TG    TP  IS
Sbjct: 2077 GWSSSGTSTGASN-TPGEIS 2095



 Score =  110 bits (274), Expect = 2e-23
 Identities = 98/398 (24%), Positives = 156/398 (39%), Gaps = 59/398 (14%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDN-FGVYIDNYHCDPN 1990
            C   EC   C  +G+ H  TFDG  YS+ G C Y  +E+     +  F +  ++  C   
Sbjct: 1308 CTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCC-E 1366

Query: 1991 DKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVY-----QSGI 2045
            D ++C R +IV  + Q ++++   +  ++       +  A  Y  + + +Y     Q+GI
Sbjct: 1367 DGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGI 1426

Query: 2046 NYVVDI-PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNC 2104
              + D    L V++  N            +     G CG       DD       + S  
Sbjct: 1427 IVIWDKNTRLSVILDPN------------WNGKVCGLCGNNNGDLKDDFTTRYSSVASGA 1474

Query: 2105 EAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQC 2164
                + W            S   +   A T P    + P+        C++++DS F  C
Sbjct: 1475 LEFGNSWKT----------SQECSDTVAQTFPCD--SNPYCKAWAVRKCEILRDSTFRDC 1522

Query: 2165 HALVPPQHYYDACVFDSCF--MPGSSLE-CASLQAYAALCAQQNICLDWRNHTHGACLVE 2221
            H  V P  Y+D C+ ++C   M G  L  C ++  YA  C+   +C+ WR      C V 
Sbjct: 1523 HNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRK--PNLCPVY 1580

Query: 2222 CPSHR-------EYQACGPAEEPTCKSSSSQQNNTVLVEGCF--CPEGTMNYAPGFD--- 2269
            C  +         Y+ CG     TCK     Q  + L+EGC+  CP+     AP  D   
Sbjct: 1581 CDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDS----APYLDENT 1636

Query: 2270 ---VCVKTCGCVGPDNVPREFGEHFEFDC-KNCVCLEG 2303
               V +  C C   D +P   G   E +C + C C+ G
Sbjct: 1637 MKCVSLSECSCFYNDVIPA--GGVIEDNCGRTCYCIAG 1672



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 124/565 (21%), Positives = 214/565 (37%), Gaps = 93/565 (16%)

Query: 1903 IVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWG-------------DPHY 1949
            ++K EC   P  +     QP  V +  G C   +C C    W                  
Sbjct: 812  VLKAEC---PCESSGTVYQPGEVRE--GPCGS-QCTCQDAKWSCTEALCPGRCKVEGSSL 865

Query: 1950 VTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVL 2009
             TFDG+ Y++ GNC ++ V       +++ + ++   C      +C  ++ +   +   +
Sbjct: 866  TTFDGVKYNFPGNCHFLAVHN-----EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPV 920

Query: 2010 IKTVHMMPMQV-QVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN---GLSF 2065
             K V      V   ++  Q     Y    ++++ +  +Y+       V +       +  
Sbjct: 921  DKYVFNSDGTVTNDKIRNQGY---YYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQL 977

Query: 2066 SVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSS 2125
             V +P ++F  +T G CG+  N   DD +     +    +A A+ W +       CP  +
Sbjct: 978  YVSMPPNQF-TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-----CPKGN 1031

Query: 2126 STTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSL--FAQCHALVPPQHYYDACVFDSCF 2183
             ++    +++         K+      C ++ DS    A CH +V P+ Y++ C   +C 
Sbjct: 1032 PSS---CISI--------EKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCT 1080

Query: 2184 MPGSS-LECASLQAYAALCAQ-QNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKS 2241
               S    C  L  Y   CA+ +   + WR    G C   CPS   ++    A   +C+S
Sbjct: 1081 CENSQDCLCTILGNYVKACAEKETYIVGWRT---GLCEHSCPSGLVFKYNVKACNSSCRS 1137

Query: 2242 SSSQQNNT----VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKN 2297
             S +  +     V V+GC CP+       G  V    C C   D V +  G+    D   
Sbjct: 1138 LSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQP-GKLIHIDDNK 1196

Query: 2298 CVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPAD---------TCCNITVCKCN 2348
            CVC +G   ++C      Q P+   +++ +  A  V+ +D         TC    +   +
Sbjct: 1197 CVCRDG--ILLC------QIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFD 1248

Query: 2349 TSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCV 2408
             +L  ++   CP G    SK +    C F    +   C  G  EY  GS V S  C +C 
Sbjct: 1249 ENLPCKRGCFCPEGMVRNSKGI----CVF---PNDCPCSFGGREYDEGS-VTSVGCNECT 1300

Query: 2409 CTDKVDNNTLLNVIACTHVPCNTSC 2433
            C        +    +CT   C T C
Sbjct: 1301 C--------IKGSWSCTQNECQTIC 1317



 Score = 90.1 bits (222), Expect = 3e-17
 Identities = 84/327 (25%), Positives = 128/327 (39%), Gaps = 21/327 (6%)

Query: 29   TRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASD-CRGSYKEFAVHLKRGPGQAEA 87
            T+N    +C  +G  H +TFDG  + F GLC Y+F  D C      F +  +  P   + 
Sbjct: 1309 TQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDG 1368

Query: 88   PAGVESILLTIKDDTIYLT--RHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTL 145
                  I++  +D  I L   +  AV +         +    I     Y  +  + G+ +
Sbjct: 1369 LTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIV 1428

Query: 146  MWNREDALMLELDTKFRNHTCGLCGDYNG-LQSYSEFLSDGVLFSPLEFGNMQKINQPDV 204
            +W++   L + LD  +    CGLCG+ NG L+         V    LEFGN  K +Q   
Sbjct: 1429 IWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE-- 1486

Query: 205  VCEDPEEEVAPASCSEH-----RAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRC-- 257
             C D   +  P   + +       +CE +L    F DC + V    Y   C ++ C C  
Sbjct: 1487 -CSDTVAQTFPCDSNPYCKAWAVRKCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDM 1544

Query: 258  PGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNL--VYLESGSPCMD 315
             G     C+ VA ++  CS A G   +WR              PG     Y   G+    
Sbjct: 1545 EGKYLGFCTAVAMYAEACS-AVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAK 1603

Query: 316  TCSHLEVSSLCEEHRMDGCF--CPEGA 340
            TC    V        ++GC+  CP+ A
Sbjct: 1604 TCKDQLVGQKFSS-LLEGCYAKCPDSA 1629



 Score = 82.0 bits (201), Expect = 7e-15
 Identities = 112/443 (25%), Positives = 164/443 (37%), Gaps = 44/443 (9%)

Query: 1324 PTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1383
            PT +  +  +TT T I +T       T  G  T  + P  TT++   T T  G   P T 
Sbjct: 1681 PTNSTFAVSTTTATTILSTGAAITLVTG-GPSTAASIPAITTSSSETTGTTLG---PLTE 1736

Query: 1384 PITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1443
            P TT  T T  P        TS     T  V+PT T       TT  +   TT   +   
Sbjct: 1737 PFTTGITETSVPI-----ISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASEN- 1790

Query: 1444 TGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTT 1503
            T  +A TP     T  V    TP G   P  T ++ +T V+      G+ T +P A  T+
Sbjct: 1791 TSERAGTPRVSGETPAVGGGSTP-GEAGPGAT-VSGSTGVS-----AGSITASPGASATS 1843

Query: 1504 TTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQT 1563
            +  + + T TG      T  T++   +       T     +   + + +T   + TG+  
Sbjct: 1844 SESSKSGT-TGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTGSSP 1902

Query: 1564 PTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTA 1623
            P    +T  +  +P     GT     V  T       +    ST+ +     +  +  TA
Sbjct: 1903 P--GKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTA 1960

Query: 1624 TPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIA----------ELTTSN 1673
              + TG   P    +S T  V+P  TP    +  P        +           LT  N
Sbjct: 1961 GTSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLN 2020

Query: 1674 PPPESSTPQTS--RSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPP 1731
            P     TP  S   +TSSP+++ T   S     I  +    P TP     TSGG   S  
Sbjct: 2021 PAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGG--ATSGGKITS-- 2076

Query: 1732 PSTTTSPPGTPTRGTTTGSSSAP 1754
                    G  + GT+TG+S+ P
Sbjct: 2077 --------GWSSSGTSTGASNTP 2091



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 104/413 (25%), Positives = 152/413 (36%), Gaps = 62/413 (15%)

Query: 1485 PTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPT 1544
            PT +     T T T I +T       T  G  T  S P  TT++   T T  G   P   
Sbjct: 1681 PTNSTFAVSTTTATTILSTGAAITLVTG-GPSTAASIPAITTSSSETTGTTLG---PLTE 1736

Query: 1545 PISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP 1604
            P +T  T T  P  +     T+     T  V+PT T       TT  +   TT   +   
Sbjct: 1737 PFTTGITETSVPIIS-----TSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASEN- 1790

Query: 1605 TSTKSTTVTPITTTTTVTATPTP------------TGTQTPTMIPISTTTTVTPTPTPTT 1652
            TS ++ T      T  V    TP            TG    + I  S   + T + +  +
Sbjct: 1791 TSERAGTPRVSGETPAVGGGSTPGEAGPGATVSGSTGVSAGS-ITASPGASATSSESSKS 1849

Query: 1653 GSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTS---SPLTESTTLLSTLPPAIEMTS 1709
            G+TGP     T   +   TS+      T Q+  ST+   S +T  T+   + PP  ++T 
Sbjct: 1850 GTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTGSSPPG-KLTR 1908

Query: 1710 TAPPSTP-----------TAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPST 1758
             +P S              A T  +G +T     ST  S   T + G+   + ++ T  T
Sbjct: 1909 PSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDT 1968

Query: 1759 VQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGE-EVYNGTYGDT 1817
                T  + TP  +P +TP           P S             PGE ++ N ++G +
Sbjct: 1969 GPGNTAVSGTPVVSPGATPGA---------PGS-----------STPGEADIGNTSFGKS 2008

Query: 1818 CYFVNCSLSCTLEFYNWSCP--STPSPTPTP-SKSTPTPSKPSSTPSKPTPGT 1867
                + SL+     +    P  S  S T +P SK T   S  + T S   PGT
Sbjct: 2009 GKSGHDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGT 2061



 Score = 48.9 bits (115), Expect = 7e-05
 Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 5/112 (4%)

Query: 2153 CQLIKDSLFAQCHALVPPQHYYDA-CVFDSCFMPGSSLECASLQAYAALCAQQN--ICLD 2209
            C  I  + F +C  +    + Y   C+ + C     +  C +    + LCA         
Sbjct: 689  CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 748

Query: 2210 WRNHTHGACLVE-CPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEG 2260
            WR+ +   C  + CP    Y+ CGP+   TC + +  Q++   V GC CPEG
Sbjct: 749  WRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSE-CVSGCTCPEG 799



 Score = 40.8 bits (94), Expect = 0.018
 Identities = 34/123 (27%), Positives = 47/123 (38%), Gaps = 28/123 (22%)

Query: 2219 LVECPSHREYQACG-PAEEPTCKSSSSQQNNTVLVE------GCFCPEGTMNYAPGFDVC 2271
            L  C    EY  C  P  +     + S +N  V  E      GCFCPEG +  + G    
Sbjct: 1214 LQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGI--- 1270

Query: 2272 VKTCGCVGPDNVPREFGEHFEFD--------CKNCVCLEGGSGIICQPKRCSQKPVTHCV 2323
                 CV P++ P  FG   E+D        C  C C++G     C    C  + + H  
Sbjct: 1271 -----CVFPNDCPCSFGGR-EYDEGSVTSVGCNECTCIKGSWS--CTQNEC--QTICHIY 1320

Query: 2324 EDG 2326
             +G
Sbjct: 1321 GEG 1323


>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
          Length = 2813

 Score =  569 bits (1466), Expect = e-161
 Identities = 393/1278 (30%), Positives = 557/1278 (43%), Gaps = 183/1278 (14%)

Query: 6    ARLAAVCLALSLAGGSELQTEGRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFAS 65
            AR A V LAL+L     L  EG         CS +G+    TFDG ++ F G C Y  A 
Sbjct: 4    ARFAGVLLALALILPGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG 63

Query: 66   DCRGSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAV------VST 119
             C+          + G          + + L++     +   HL V NG V      VS 
Sbjct: 64   GCQKRSFSIIGDFQNG----------KRVSLSVYLGEFF-DIHLFV-NGTVTQGDQRVSM 111

Query: 120  PHYSPGLLIEKSDAYTKVYSRA-GLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSY 178
            P+ S GL +E    Y K+   A G     +      + L  ++ N TCGLCG++N     
Sbjct: 112  PYASKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAED 171

Query: 179  SEFLSDGVLFS-PLEFGNM----------QKINQPDVVCE-------------------- 207
                 +G L S P +F N           ++ + P   C                     
Sbjct: 172  DFMTQEGTLTSDPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKST 231

Query: 208  ----------DPEEEVA-----------------PASCSEHRAECERLLTAEAFAD---C 237
                      DPE  VA                 PA     R   +  +    + D   C
Sbjct: 232  SVFARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSAC 291

Query: 238  QDLVP--------LEPYLRACQQ------------DRCRCPGGDT-----CVCSTVAEFS 272
              + P        + P  R CQ             D C CP G       CV ST     
Sbjct: 292  SPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECP-- 349

Query: 273  RQCSHAGGR--PGNW--RTATSAVSPGA-----SKTCPGN-LVYLESGSPCMDT------ 316
              C H+G R  PG    R   + +   +     ++ CPG  LV  +S     D       
Sbjct: 350  --CVHSGKRYPPGTSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFS 407

Query: 317  --CSHLEVSSLCEEHR----MDGCFCPEGAQADLPKTV-VLLADKKKNVVVFKSDGSVLL 369
              C +L ++  C++H     ++   C +   A   ++V V L     ++V  K    V +
Sbjct: 408  GICQYL-LARDCQDHSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAM 466

Query: 370  NELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLC 429
            +   V LP +     +    +    V ++ G  LQ+      +L V L     G+  GLC
Sbjct: 467  DGQDVQLPLLKGDLRI--QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLC 524

Query: 430  GNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWC 489
            GN+NG +GDDF T SGL E     F N WK    C D      DPC+LN     ++E  C
Sbjct: 525  GNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMTRFSEEAC 584

Query: 490  SLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWG 549
            ++L  T   F  CH AV P  Y + C+YD C+C +  +CLC AL+SYA AC  +GV +  
Sbjct: 585  AVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGRGVRV-A 641

Query: 550  WREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDE 609
            WRE    +   +CP  QV+L   T C  TCRSLS  D  C E  A ++GC CP   ++DE
Sbjct: 642  WREP--GRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNE--ACLEGCFCPPGLYMDE 697

Query: 610  KGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQ----------- 658
            +G CVP A+C CY+ G   +  D+       C C DG +HC    + G            
Sbjct: 698  RGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSSPL 757

Query: 659  --------SCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDD 710
                    SC  P + + C      A       +CQ          CVSGC+CP G++  
Sbjct: 758  SHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRH 817

Query: 711  GRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYI 770
                CV  + CPC H    Y+ G  +K+ CNTC C+  +W CT  VC  TCS  G  HY+
Sbjct: 818  -ENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYL 876

Query: 771  TFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTEL 830
            TFDG  Y F G C YV VQDYCG N   G+F I+  N  C    V C K + I +   E+
Sbjct: 877  TFDGLKYLFPGECQYVLVQDYCGSNP--GTFRILVGNKGCSHPSVKCKKRVTILVEGGEI 934

Query: 831  KLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVC 890
            +L D   V ++R       +   E G+Y+++     + V+WD+  ++ + L  +Y+  VC
Sbjct: 935  ELFD-GEVNVKRPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVC 993

Query: 891  GLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPD-----VSTNPEPCSLNPHRR 945
            GLCGNFD   NND T+ +  V    +DFGNSWK +  C D     + ++P  C  N  ++
Sbjct: 994  GLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQ 1053

Query: 946  SWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTK 1005
            +  +  C IL S VF  C+  VDP+P+ + C++D+CSC++ GDC CFC  +A+YA  C +
Sbjct: 1054 TMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQ 1113

Query: 1006 EGACVFWRTPDLCPIFCDYYN---PPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLE 1062
             G  V WRT  LCP  C+  N     +ECEW Y  C      TC+    +     V  +E
Sbjct: 1114 HGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPL--ACPVQCVE 1171

Query: 1063 GCYPRCPKDRPIYEEDLKKCVTADKCG-CYVEDTHYPPGASV---PTE-ETCKSCVC--T 1115
            GC+  CP  + I +E L+ CV  + C  C V    +  G  V   P++ E C+ C C   
Sbjct: 1172 GCHAHCPPGK-ILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVV 1230

Query: 1116 NSSQVVCRPEEGKILNQT 1133
            N +   C+   G ++  T
Sbjct: 1231 NLTCEACQEPGGLVVPPT 1248



 Score =  253 bits (646), Expect = 2e-66
 Identities = 211/809 (26%), Positives = 314/809 (38%), Gaps = 142/809 (17%)

Query: 1872 CPDFDP-PRQENETWWLCD-CFMATCKYNNTVEIV--KVECEPPPMPTCSNGLQPVRVED 1927
            C D D   ++  + W L D C   TC+ +    +   +V C+    P+C N   PV+VE+
Sbjct: 1879 CMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEE 1938

Query: 1928 PDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHC 1987
              GC   W C C CTG    H VTFDG  +   G+C+YVL +     ++   V + N  C
Sbjct: 1939 TCGC--RWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLE---VILHNGAC 1993

Query: 1988 DPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSG-IN 2046
             P  +  C +++ V+H    V + +       ++V VN + V++PY    +EV   G I 
Sbjct: 1994 SPGARQGCMKSIEVKHSALSVELHS------DMEVTVNGRLVSVPYVGGNMEVNVYGAIM 2047

Query: 2047 YVVDIPELGVLVSY--NGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNC 2104
            + V    LG + ++      F ++L    F + T G CG C    ++D +L  G + ++ 
Sbjct: 2048 HEVRFNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDW 2107

Query: 2105 EAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQC 2164
            +    +W V  P +   P        P                  S  CQ++   LFA+C
Sbjct: 2108 KTLVQEWTVQRPGQTCQPILEEQCLVP-----------------DSSHCQVLLLPLFAEC 2150

Query: 2165 HALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPS 2224
            H ++ P  +Y  C  DSC        C  + +YA LC    +C+DWR  T   C + CP 
Sbjct: 2151 HKVLAPATFYAICQQDSCH---QEQVCEVIASYAHLCRTNGVCVDWR--TPDFCAMSCPP 2205

Query: 2225 HREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTC-GCVGPDNV 2283
               Y  C       C  + S   +    EGCFCP   +    G  V  + C  C+G D V
Sbjct: 2206 SLVYNHCEHGCPRHCDGNVSSCGDHP-SEGCFCPPDKV-MLEGSCVPEEACTQCIGEDGV 2263

Query: 2284 PREFGEHFEFD---CKNCVCLEGGS----------------------------------- 2305
              +F E +  D   C+ C CL G                                     
Sbjct: 2264 QHQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEY 2323

Query: 2306 GIICQPKRCSQKPVTHCVEDGTYLATEVNPAD---------------------------- 2337
              +C P  C   PV HC E G    T  NP +                            
Sbjct: 2324 ECVCDPVSCDLPPVPHC-ERGLQ-PTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLP 2381

Query: 2338 -----TCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAE 2392
                  CC+   C CN   C      CPLG+ + S       C    C    VCVH +  
Sbjct: 2382 TLRKTQCCDEYECACN---CVNSTVSCPLGY-LASTATNDCGCTTTTCLPDKVCVHRSTI 2437

Query: 2393 YQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQ 2452
            Y P    +   C  C CTD  D    L V  C+  PC  SC  GF  +   GECC +C  
Sbjct: 2438 Y-PVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGECCGRCLP 2496

Query: 2453 THCII----KRPDNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASI 2508
            + C +     R D+Q      G   + P+N C    CV++  ++     N++CP  +  +
Sbjct: 2497 SACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCPQLEVPV 2556

Query: 2509 CIPG-SITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVM 2567
            C  G  ++   + CC +C  R E    C         +  G  KTV+++ C+ +C   V 
Sbjct: 2557 CPSGFQLSCKTSACCPSC--RCERMEAC-----MLNGTVIGPGKTVMIDVCT-TCRCMVQ 2608

Query: 2568 YSA----KAQALDHSCSCC----KEEKTS 2588
                   K +    +C+ C    KEE  +
Sbjct: 2609 VGVISGFKLECRKTTCNPCPLGYKEENNT 2637



 Score =  131 bits (329), Expect = 1e-29
 Identities = 147/591 (24%), Positives = 215/591 (36%), Gaps = 96/591 (16%)

Query: 1911 PPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 1970
            PP  + S         +    C + EC   C   G  H+ +FD  Y+++ G C Y+L  +
Sbjct: 358  PPGTSLSRDCNTCICRNSQWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARD 417

Query: 1971 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVR-HETQEVLIKTVHMMPMQVQVQVNRQAV 2029
                  +F + I+   C  +    C R++ VR       L+K  H       V ++ Q V
Sbjct: 418  CQD--HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKH----GAGVAMDGQDV 471

Query: 2030 ALPYKKYGLEVYQS-----GINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGT 2084
             LP  K  L +  +      ++Y  D+      + ++G    +      +   T G CG 
Sbjct: 472  QLPLLKGDLRIQHTVTASVRLSYGEDLQ-----MDWDGRGRLLVKLSPVYAGKTCGLCGN 526

Query: 2085 CTNTTSDDCILPSGEIVSNCEAAADQW-LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTP 2143
                  DD + PSG      E   + W L  D       HS      P +T         
Sbjct: 527  YNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT--------- 577

Query: 2144 HKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC-FMPGSSLECASLQAYAALCA 2202
                     C ++    F  CH  V P  Y   C +D C    G    C +L +YAA CA
Sbjct: 578  ---RFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACA 634

Query: 2203 QQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSS--SQQNNTVLVEGCFCPEG 2260
             + + + WR    G C + CP  + Y  CG     TC+S S   ++ N   +EGCFCP G
Sbjct: 635  GRGVRVAWRE--PGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPG 692

Query: 2261 TMNYAPGFDVCVKTCGCVGPDNV--PRE-FGEHFEFDCKNCVCLEG-----GSGI--ICQ 2310
                  G  V    C C     +  P + F +H       C C +G      SG+     
Sbjct: 693  LYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTM----CYCEDGFMHCTMSGVPGSLL 748

Query: 2311 PKRCSQKPVTH----CVEDGTYLATEVNPAD-----------TCCNITVCKCNTSLCKEK 2355
            P      P++H     +     +   V PAD           TC N  + +C +  C   
Sbjct: 749  PDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDL-ECMSMGC-VS 806

Query: 2356 PSVCPLGF-EVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVD 2414
              +CP G    +++ V    CP         C H   EY PG  V    C  CVC D+  
Sbjct: 807  GCLCPPGMVRHENRCVALERCP---------CFHQGKEYAPGETV-KIGCNTCVCRDRKW 856

Query: 2415 NNTLLNVIACTHVPCNTSCS----------PGFELMEAPGECCKKCEQTHC 2455
            N        CT   C+ +CS           G + +  PGEC     Q +C
Sbjct: 857  N--------CTDHVCDATCSTIGMAHYLTFDGLKYL-FPGECQYVLVQDYC 898



 Score =  122 bits (306), Expect = 5e-27
 Identities = 127/453 (28%), Positives = 179/453 (39%), Gaps = 85/453 (18%)

Query: 696  ECVSGCVCPDG--LMDDGRGGCV--VEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWV 751
            +C +    PDG  L+   R  C   +   CP        +S + +KV+  TC C   RW 
Sbjct: 1898 QCHTVTCQPDGQTLLKSHRVNCDRGLRPSCP--------NSQSPVKVE-ETCGC---RWT 1945

Query: 752  CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCG 811
            C   VC G+     + H +TFDG+ +   G CSYV  Q+            +I  N  C 
Sbjct: 1946 CP-CVCTGS----STRHIVTFDGQNFKLTGSCSYVLFQN------KEQDLEVILHNGACS 1994

Query: 812  TTGVT-CSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT----TREVGQYLVVESST- 865
                  C K+I++      ++L     V +    G  V+        EV  Y  +     
Sbjct: 1995 PGARQGCMKSIEVKHSALSVELHSDMEVTVN---GRLVSVPYVGGNMEVNVYGAIMHEVR 2051

Query: 866  ----GIIVIWDKRTTVF-IKLAP-SYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFG 919
                G I  +  +   F ++L+P ++     GLCG  D    NDF  RD  V +      
Sbjct: 2052 FNHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLV 2111

Query: 920  NSW---KEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEAC 976
              W   +   TC  +    E C +           C +L   +F+ CH  + P  FY  C
Sbjct: 2112 QEWTVQRPGQTCQPILE--EQCLVPD------SSHCQVLLLPLFAECHKVLAPATFYAIC 2163

Query: 977  VHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCD----YYNPPHECE 1032
              DSC        E  C  +ASYA  C   G CV WRTPD C + C     Y +  H C 
Sbjct: 2164 QQDSCHQ------EQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCP 2217

Query: 1033 WHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKC-GCY 1091
             H +  GN S  +C    G H +      EGC+  CP D+ + E     CV  + C  C 
Sbjct: 2218 RHCD--GNVS--SC----GDHPS------EGCF--CPPDKVMLE---GSCVPEEACTQCI 2258

Query: 1092 VED--THYPPGASVPTEETCKSCVCTNSSQVVC 1122
             ED   H    A VP  + C+ C C +  +V C
Sbjct: 2259 GEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNC 2291



 Score =  120 bits (301), Expect = 2e-26
 Identities = 108/452 (23%), Positives = 157/452 (34%), Gaps = 76/452 (16%)

Query: 2230 ACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPREF 2287
            +C P   PT + +            C C   T++   G+     T  CGC     +P + 
Sbjct: 2374 SCPPHRLPTLRKTQCCDEYEC---ACNCVNSTVSCPLGYLASTATNDCGCTTTTCLPDKV 2430

Query: 2288 ----------GEHFEFDCKNCVCLEGGSGII-CQPKRCSQKPVTHCVEDG-TYLATEVNP 2335
                      G+ +E  C  C C +    ++  +  +CSQKP       G TY+  E   
Sbjct: 2431 CVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQKPCEDSCRSGFTYVLHEGEC 2490

Query: 2336 ADTC---------------------------------CNITVC----------KCNTSLC 2352
               C                                 C I  C          + N S  
Sbjct: 2491 CGRCLPSACEVVTGSPRGDSQSSWKSVGSQWASPENPCLINECVRVKEEVFIQQRNVSCP 2550

Query: 2353 KEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDK 2412
            + +  VCP GF++  K     CCP   CE    C+       PG  V    C  C C  +
Sbjct: 2551 QLEVPVCPSGFQLSCKT--SACCPSCRCERMEACMLNGTVIGPGKTVMIDVCTTCRCMVQ 2608

Query: 2413 VDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQHVILKPGDF 2472
            V   +    + C    CN  C  G++     GECC +C  T C I+    Q + LK  + 
Sbjct: 2609 VGVISGFK-LECRKTTCNP-CPLGYKEENNTGECCGRCLPTACTIQLRGGQIMTLKRDET 2666

Query: 2473 KSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIP--GSITFMPNGCCKTCTPRNE 2530
              D  +  T F  V    +         CP FD   C+   G I  +P  CC TC     
Sbjct: 2667 LQDGCD--THFCKVNERGEYFWEKRVTGCPPFDEHKCLAEGGKIMKIPGTCCDTCEEPE- 2723

Query: 2531 TRVPCSTVPVTTEVSYAGCTKT---VLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEEKT 2587
                C+ +    +    G  K+   V +++C G C +  MYS     +   CSCC   +T
Sbjct: 2724 ----CNDITARLQYVKVGSCKSEVEVDIHYCQGKCASKAMYSIDINDVQDQCSCCSPTRT 2779

Query: 2588 SQREVVLSCPNGGSLTHTYTHIESCQCQDTVC 2619
               +V L C NG  + H   +   C+C    C
Sbjct: 2780 EPMQVALHCTNGSVVYHEVLNAMECKCSPRKC 2811



 Score =  109 bits (273), Expect = 3e-23
 Identities = 117/473 (24%), Positives = 178/473 (37%), Gaps = 75/473 (15%)

Query: 1898 NNTVEIVKVEC-----EPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTF 1952
            N  V + +  C     E  P  T   G       D    C    CD  C+  G  HY+TF
Sbjct: 819  NRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCSTIGMAHYLTF 878

Query: 1953 DGLYYSYQGNCTYVLVEEISPS-VDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIK 2011
            DGL Y + G C YVLV++   S    F + + N  C  +  V C + + +  E  E+ + 
Sbjct: 879  DGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCS-HPSVKCKKRVTILVEGGEIEL- 936

Query: 2012 TVHMMPMQVQVQVNRQAVALPYK-KYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRLP 2070
                     +V V R     P K +   EV +SG   ++ + +   +V    LS SV L 
Sbjct: 937  ------FDGEVNVKR-----PMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLK 985

Query: 2071 YHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKR 2130
               +     G CG      ++D    + ++  +     + W V+          + T K 
Sbjct: 986  -QTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSS-------QCADTRKV 1037

Query: 2131 PAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC---FMPGS 2187
            P  + P        K       C+++   +F  C+ LV P+ Y D C++D+C    +   
Sbjct: 1038 PLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDC 1097

Query: 2188 SLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHR----------EYQACGPAEEP 2237
            +  C ++ AYA +CAQ    + WR  T   C   C               Y +C PA + 
Sbjct: 1098 ACFCDTIAAYAHVCAQHGKVVTWRTAT--LCPQSCEERNLRENGYECEWRYNSCAPACQV 1155

Query: 2238 TCKSSSSQQNNTVLVEGC--FCPEGTMNYAPGFDVCVKTCGCVGPDNVP------REFG- 2288
            TC+           VEGC   CP G +      D  ++T  CV P++ P      R F  
Sbjct: 1156 TCQHPEPLACPVQCVEGCHAHCPPGKI-----LDELLQT--CVDPEDCPVCEVAGRRFAS 1208

Query: 2289 -----------EHFEF---DCKNCVC--LEGGSGIICQPKRCSQKPVTHCVED 2325
                       EH +    D  N  C   +   G++  P      P T  VED
Sbjct: 1209 GKKVTLNPSDPEHCQICHCDVVNLTCEACQEPGGLVVPPTDAPVSPTTLYVED 1261



 Score =  100 bits (249), Expect = 2e-20
 Identities = 105/381 (27%), Positives = 156/381 (40%), Gaps = 38/381 (9%)

Query: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000
            C+ +G     TFDG  YS+ G C+Y+L         +F +  D  +     +VS    L 
Sbjct: 35   CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR--SFSIIGDFQN---GKRVSLSVYLG 89

Query: 2001 VRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSY 2060
               +        +H+  +   V    Q V++PY   GL +      Y +     G +   
Sbjct: 90   EFFD--------IHLF-VNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARI 140

Query: 2061 NGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPH 2120
            +G      L   R+ N T G CG       DD +   G + S+    A+ W ++   +  
Sbjct: 141  DGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSS-GEQW 199

Query: 2121 CPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKD-SLFAQCHALVPPQHYYDACVF 2179
            C  +S  +    ++     K    +       CQL+K  S+FA+CH LV P+ +   C  
Sbjct: 200  CERASPPSSSCNISSGEMQKGLWEQ-------CQLLKSTSVFARCHPLVDPEPFVALCEK 252

Query: 2180 DSCFMPGSSLECA--SLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEE 2236
              C   G  LECA  +L  YA  CAQ+ + L  W +H+  AC   CP+  EY+ C     
Sbjct: 253  TLCECAG-GLECACPALLEYARTCAQEGMVLYGWTDHS--ACSPVCPAGMEYRQCVSPCA 309

Query: 2237 PTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCV--GPDNVPREFGEHFEF 2293
             TC+S   ++      V+GC CPEG +    G  V    C CV  G    P   G     
Sbjct: 310  RTCQSLHINEMCQERCVDGCSCPEGQL-LDEGLCVESTECPCVHSGKRYPP---GTSLSR 365

Query: 2294 DCKNCVCLEGGSGIICQPKRC 2314
            DC  C+C    S  IC  + C
Sbjct: 366  DCNTCIC--RNSQWICSNEEC 384



 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 82/312 (26%), Positives = 125/312 (40%), Gaps = 32/312 (10%)

Query: 36   VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESIL 95
            VC+     H  TFDG  F+  G C Y      +   ++  V L  G     A  G     
Sbjct: 1949 VCTGSSTRHIVTFDGQNFKLTGSCSYVL---FQNKEQDLEVILHNGACSPGARQGCMK-S 2004

Query: 96   LTIKDDTIYLTRHL---AVLNGAVVSTPHYSPGLLIEKSDA--YTKVYSRAGLTLMWN-R 149
            + +K   + +  H      +NG +VS P+    + +    A  +   ++  G    +  +
Sbjct: 2005 IEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQ 2064

Query: 150  EDALMLELDTK-FRNHTCGLCG--DYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVV 205
             +   L+L  K F + T GLCG  D NG   +   L DG + +  +       + +P   
Sbjct: 2065 NNEFQLQLSPKTFASKTYGLCGICDENGANDF--MLRDGTVTTDWKTLVQEWTVQRPGQT 2122

Query: 206  CEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCVC 265
            C+   EE      S H   C+ LL    FA+C  ++    +   CQQD C        VC
Sbjct: 2123 CQPILEEQCLVPDSSH---CQVLL-LPLFAECHKVLAPATFYAICQQDSCH----QEQVC 2174

Query: 266  STVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVSSL 325
              +A ++  C    G   +WRT         + +CP +LVY      C   C    VSS 
Sbjct: 2175 EVIASYAHLC-RTNGVCVDWRTPDF-----CAMSCPPSLVYNHCEHGCPRHCDG-NVSS- 2226

Query: 326  CEEHRMDGCFCP 337
            C +H  +GCFCP
Sbjct: 2227 CGDHPSEGCFCP 2238



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 85/346 (24%), Positives = 129/346 (37%), Gaps = 55/346 (15%)

Query: 336  CPEGAQADLPKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSY---- 391
            C  GA+    K++ +        V   SD  V +N   V++P+V  +  V    +     
Sbjct: 1993 CSPGARQGCMKSIEVKHSALS--VELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEV 2050

Query: 392  ------HIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASG 445
                  HI          Q+QL+P         +    +  GLCG  +    +DF    G
Sbjct: 2051 RFNHLGHIFTFTPQNNEFQLQLSP---------KTFASKTYGLCGICDENGANDFMLRDG 2101

Query: 446  LVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSA 505
             V          W  Q         L++ C +   S     H   LL      F  CH  
Sbjct: 2102 TVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDSS-----HCQVLLLPL---FAECHKV 2153

Query: 506  VDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWR-EHVCNKDVGSCPN 564
            + PA +Y  C+ D+C    +++ +C  ++SYA  C   GV +  WR    C     SCP 
Sbjct: 2154 LAPATFYAICQQDSC----HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFC---AMSCPP 2205

Query: 565  SQVFLYNLTTCQQTC-RSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCS-CY 622
            S V+ +    C + C  ++S    H      P +GC CP    + E G CVP   C+ C 
Sbjct: 2206 SLVYNHCEHGCPRHCDGNVSSCGDH------PSEGCFCPPDKVMLE-GSCVPEEACTQCI 2258

Query: 623  H----RGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPK 664
                 +  +LEA     +  + C C  G    R++    Q C   K
Sbjct: 2259 GEDGVQHQFLEAWVPDHQPCQICTCLSG----RKVNCTTQPCPTAK 2300


>gi|239755460 PREDICTED: similar to mucin, partial [Homo sapiens]
          Length = 1064

 Score =  536 bits (1381), Expect = e-151
 Identities = 340/1075 (31%), Positives = 473/1075 (44%), Gaps = 96/1075 (8%)

Query: 1579 PTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMI-- 1636
            P PT   T TT   TT+TT  P  TP+   +T+ TP++ T+T   + + T    P     
Sbjct: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101

Query: 1637 -PISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTEST 1695
             P+   T       P+ G  G    T    I         PE  T    R+ S P     
Sbjct: 102  HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIE 161

Query: 1696 TLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPT 1755
             L   +  + E            P      + +      T  P G P    T   +S PT
Sbjct: 162  HLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCET--PRGCPVTSVTPYGTS-PT 218

Query: 1756 PSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVY-NGTY 1814
             +   + +TS  + +    S  S    +    Y +    C V  D  Y  G  +Y +   
Sbjct: 219  NALYPSLSTSMVSASVASTSVASSSVASSSVAYSTQTCFCNVA-DRLYPAGSTIYRHRDL 277

Query: 1815 GDTCYFVNCSLSC-TLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECP 1873
               CY+  CS  C  +   +  CPST  P P P+ S      PS + S+P        CP
Sbjct: 278  AGHCYYALCSQDCQVVRGVDSDCPSTTLP-PAPATS------PSISTSEPVTELG---CP 327

Query: 1874 DFDPPRQENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCW 1933
            +  PPR++ ETW   +C  ATC+ NN + +    C     PTC+NG   V+V D DGCC 
Sbjct: 328  NAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCH 387

Query: 1934 HWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKV 1993
            H++C C C+GWGDPHY+TFDG YY++  NCTYVLV++I P   +F V +DNY C   D +
Sbjct: 388  HYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGL 447

Query: 1994 SCPRTLIVRHETQEVLI--KTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
            SCPR++I+ +    V++  K VH + M  ++  N + V+  ++K G+ V + G+     I
Sbjct: 448  SCPRSIILEYHQDRVVLTRKPVHGV-MTNEIIFNNKVVSPGFRKNGIVVSRIGVKMYATI 506

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 2111
            PELGV V ++GL FSV +P+ +F            N T   C                  
Sbjct: 507  PELGVQVMFSGLIFSVEVPFSKFA-----------NNTEGQCXXXXXXX----------- 544

Query: 2112 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQ 2171
                                         TTP   C PSP+CQLI   +F  CH ++PP 
Sbjct: 545  -----------------------------TTPPAPCLPSPICQLILSKVFEPCHTVIPPL 575

Query: 2172 HYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQAC 2231
             +Y+ CVFD C M    + C+SL+ YAALCA  +IC+DWR  T   C   CP+ + YQ C
Sbjct: 576  LFYEGCVFDRCHMTDLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKVYQPC 635

Query: 2232 GPAEEPTCKSSSSQQNNTV-----LVEGCFCPEGTMNYAPGFDVCVKT-C-GCVGPDNVP 2284
            GP+    C  + S     +     + EGCFCPEG   ++    VCV T C  C+GP   P
Sbjct: 636  GPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTLFSTSAQVCVPTGCPRCLGPHGEP 695

Query: 2285 REFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITV 2344
             + G     DC+ C C      + C+PK C   P   C   G         A  CC    
Sbjct: 696  VKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPA--CPLPGFVPVPAAPQAGQCCPQYS 753

Query: 2345 CKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKC 2404
            C CNTS C  KP  CP G         G CCP   C S  VC      YQPG+ V SS C
Sbjct: 754  CACNTSRC-PKPVGCPEGARAIPTYQEGACCPVQNC-SWTVCSINGTLYQPGAVVSSSLC 811

Query: 2405 QDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQH 2464
            + C C       +   V++C    CNT C  GFE  E  G+CC  C Q  C+     +  
Sbjct: 812  ETCRCELPGGPPSDAFVVSCETQICNTHCPVGFEYQEQSGQCCGTCVQVACVTNTSKSPA 871

Query: 2465 VILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDASICIPGSITFMPNGCCKT 2524
             +  PG+  SD  N+C    C K  + L+   +   CP    S+          +GCC+ 
Sbjct: 872  HLFYPGETWSDAGNHCVTHQCEKHQDGLVVVTTKKACPPLSCSL---DEARMSKDGCCRF 928

Query: 2525 C---TPRNETRVPCSTVPVTTEVSYAGCTKT--VLMNHCSGSCG-TFVMYSAKAQALDHS 2578
            C    P  + +  C+    +  +   GC+ +  V + +C G+CG +  MYS +   ++H 
Sbjct: 929  CPPPPPPYQNQSTCAVYHRSLIIQQQGCSSSEPVRLAYCRGNCGDSSSMYSLEGNTVEHR 988

Query: 2579 CSCCKEEKTSQREVVLSCPNGGSLTHTYTHIESCQCQDTVCGLPTGTSRRARRSP 2633
            C CC+E +TS R V L C +G S   +YT +E C C    C  P  T       P
Sbjct: 989  CQCCQELRTSLRNVTLHCTDGSSRAFSYTEVEECGCMGRRCPAPGDTQHSEEAEP 1043



 Score =  110 bits (276), Expect = 1e-23
 Identities = 126/536 (23%), Positives = 194/536 (36%), Gaps = 97/536 (18%)

Query: 619  CSCYHRGLYLEAGDVVVRQEE---RCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTAL 675
            C C        AG  + R  +    C        C+ +R +   C +  +    +   ++
Sbjct: 256  CFCNVADRLYPAGSTIYRHRDLAGHCYYALCSQDCQVVRGVDSDCPSTTLPPAPATSPSI 315

Query: 676  ATSKP-RALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGA 734
            +TS+P   L C          E  +   C +   +      +  + CP V      +   
Sbjct: 316  STSEPVTELGCPNAVPPRKKGETWATPNCSEATCEGNNVISLRPRTCPRVEKPTCANGYP 375

Query: 735  KIKV-DCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCG 793
             +KV D + C        C    C   CS +G  HYITFDG YY F  +C+YV VQ    
Sbjct: 376  AVKVADQDGC--------CHHYQCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIV- 426

Query: 794  QNSSLGSFSIITENVPCGTT-GVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTT 852
                 G F ++ +N  CG   G++C ++I +           + RVV+ R   H V  T 
Sbjct: 427  --PVYGHFRVLVDNYFCGAEDGLSCPRSIILEY--------HQDRVVLTRKPVHGVM-TN 475

Query: 853  REVGQYLVVESS---TGIIV----IWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFT 905
              +    VV       GI+V    +    T   + +   + G +  +   F   +NN   
Sbjct: 476  EIIFNNKVVSPGFRKNGIVVSRIGVKMYATIPELGVQVMFSGLIFSVEVPFSKFANN--- 532

Query: 906  TRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHS 965
                             +        +T P PC  +P         C ++ S VF  CH+
Sbjct: 533  --------------TEGQCXXXXXXXTTPPAPCLPSPI--------CQLILSKVFEPCHT 570

Query: 966  KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFW--RTPDLCPIFCD 1023
             + P  FYE CV D C      D +  CS++  YA  C     C+ W  RT  +CP  C 
Sbjct: 571  VIPPLLFYEGCVFDRCHMT---DLDVVCSSLELYAALCASHDICIDWRGRTGHMCPFTC- 626

Query: 1024 YYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVS---------YLEGCYPRCPKDRPI 1074
                    +  Y+PCG  +   C      + N S S           EGC+  CP+   +
Sbjct: 627  ------PADKVYQPCGPSNPSYC------YGNDSASLGALPEAGPITEGCF--CPEGMTL 672

Query: 1075 YEEDLKKCVTADKCGCYVEDTHYPPGASVPTEET----CKSCVCTNSS-QVVCRPE 1125
            +    + CV      C       P G  V    T    C+ C C  ++  + CRP+
Sbjct: 673  FSTSAQVCVPTGCPRCL-----GPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPK 723



 Score =  104 bits (259), Expect = 1e-21
 Identities = 69/218 (31%), Positives = 103/218 (47%), Gaps = 35/218 (16%)

Query: 1155 NICSITTRPSTL--TTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLC--------- 1203
            N+C + T  +T   TT TT    TTP+   TT+TT    +ST   +  K           
Sbjct: 42   NLCPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101

Query: 1204 ---CLWSDWINEDHPSSGSDDGDRETFDG-------VCGAPEDI---ECRSVKDPHLSLE 1250
               C W+ W + D PS G   GD+ET++        +C  PE+I   +CR+   P +++E
Sbjct: 102  HPLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIE 161

Query: 1251 QLGQKVQLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCEC-----VTQPTTMTT 1305
             LGQ VQ  C    GL+C+N+DQ+     P   CLNYE+ V CCE      VT  T   T
Sbjct: 162  HLGQVVQ--CSREEGLVCRNQDQQG----PFKMCLNYEVRVLCCETPRGCPVTSVTPYGT 215

Query: 1306 TTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTT 1343
            + T    P+  T+  + +   T  ++ S   + +  +T
Sbjct: 216  SPTNALYPSLSTSMVSASVASTSVASSSVASSSVAYST 253



 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 109/511 (21%), Positives = 182/511 (35%), Gaps = 84/511 (16%)

Query: 314 MDTCSHLEVSSLCEEHR-----MDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSDGSVL 368
           +D C+++ V  +   +      +D  FC        P++++L   + + V+  K    V+
Sbjct: 414 LDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSIILEYHQDRVVLTRKPVHGVM 473

Query: 369 LNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGL 428
            NE+  N   V+  F         I+VS  IGV++   +  +                G+
Sbjct: 474 TNEIIFNNKVVSPGFR-----KNGIVVSR-IGVKMYATIPEL----------------GV 511

Query: 429 CGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHW 488
              F+GL           VE   + FAN  + Q  C         P +  + S       
Sbjct: 512 QVMFSGLIFS--------VEVPFSKFANNTEGQ--CXXXXXXXTTPPAPCLPSPI----- 556

Query: 489 CSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLW 548
           C L+      F  CH+ + P  +Y+ C +D C+   + D +C++L  YA  C +  + + 
Sbjct: 557 CQLI--LSKVFEPCHTVIPPLLFYEGCVFDRCH-MTDLDVVCSSLELYAALCASHDICI- 612

Query: 549 GWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPV-DGCGCPD--HT 605
            WR    +    +CP  +V+     +    C     A    L    P+ +GC CP+    
Sbjct: 613 DWRGRTGHMCPFTCPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEGMTL 672

Query: 606 FLDEKGRCVPLAKCSCY-HRGLYLEAGDVVVRQEERCVCRDG--RLHCR-QIRLIGQSCT 661
           F      CVP     C    G  ++ G  V    + C C      L CR ++  +  +C 
Sbjct: 673 FSTSAQVCVPTGCPRCLGPHGEPVKVGHTVGMDCQECTCEAATWTLTCRPKLCPLPPACP 732

Query: 662 APKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDG---LMDDGRGGCVVE 718
            P           +  +      C   +     + C     CP+G   +     G C   
Sbjct: 733 LP-------GFVPVPAAPQAGQCCPQYSCACNTSRCPKPVGCPEGARAIPTYQEGACCPV 785

Query: 719 KECP---CVHNNDLYSSGAKIKVD-CNTCTCK------RGRWV--CTQAVCHGTCSIYGS 766
           + C    C  N  LY  GA +    C TC C+         +V  C   +C+  C +   
Sbjct: 786 QNCSWTVCSINGTLYQPGAVVSSSLCETCRCELPGGPPSDAFVVSCETQICNTHCPV--- 842

Query: 767 GHYITFDGKYYDFDGHCSYVAVQDYCGQNSS 797
                   +Y +  G C    VQ  C  N+S
Sbjct: 843 ------GFEYQEQSGQCCGTCVQVACVTNTS 867



 Score = 65.1 bits (157), Expect = 9e-10
 Identities = 78/313 (24%), Positives = 118/313 (37%), Gaps = 46/313 (14%)

Query: 36  VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKR-GPGQAEAPAGVESI 94
           VCS WG+ HY TFDG  + F   C Y         Y  F V +     G  +  +   SI
Sbjct: 394 VCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVYGHFRVLVDNYFCGAEDGLSCPRSI 453

Query: 95  LLTIKDDTIYLTR---HLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNRED 151
           +L    D + LTR   H  + N  + +    SPG    K+     V SR G+ +      
Sbjct: 454 ILEYHQDRVVLTRKPVHGVMTNEIIFNNKVVSPG--FRKNGI---VVSRIGVKMY----- 503

Query: 152 ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFS-PLEFGNMQKINQPDVVCEDPE 210
           A + EL                      + +  G++FS  + F       +         
Sbjct: 504 ATIPELGV--------------------QVMFSGLIFSVEVPFSKFANNTEGQCXXXXXX 543

Query: 211 EEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAE 270
               PA C    +   +L+ ++ F  C  ++P   +   C  DRC     D  VCS++  
Sbjct: 544 XTTPPAPCLP--SPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLDV-VCSSLEL 600

Query: 271 FSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHR 330
           ++  C+ +     +WR  T  + P    TCP + VY   G      C   + +SL     
Sbjct: 601 YAALCA-SHDICIDWRGRTGHMCP---FTCPADKVYQPCGPSNPSYCYGNDSASLGALPE 656

Query: 331 ----MDGCFCPEG 339
                +GCFCPEG
Sbjct: 657 AGPITEGCFCPEG 669



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 5/73 (6%)

Query: 1296 CVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTG-- 1353
            C      +   +  N  P P TT+TT  PT + TS   TTP+P+ TT+T   + T T   
Sbjct: 28   CSYNQNNLCLYSQHNLCPVP-TTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHL 86

Query: 1354 --TQTPTTTPITT 1364
              ++T  + P+T+
Sbjct: 87   SVSKTTHSQPVTS 99



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 87/393 (22%), Positives = 136/393 (34%), Gaps = 50/393 (12%)

Query: 1462 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTST 1521
            P PT + T  PTT+  T+    TP+P PT + TP     T+  +V+ T T +   T    
Sbjct: 45   PVPTTSTTSAPTTS-TTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKT-THSQPVTSDCH 102

Query: 1522 PITTTT----TVTPTPTPTGTQTPTPTPISTT------TTVTPTPTPTGTQTPTTTPITT 1571
            P+   T       P+P P G    T   I  +           T      ++     I  
Sbjct: 103  PLCAWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAESHPEVNIEH 162

Query: 1572 TTTVTPTPTPTG-------TQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTAT 1624
               V       G        Q P  + +     +    TP     T+VTP  T+ T    
Sbjct: 163  LGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSVTPYGTSPTNALY 222

Query: 1625 PTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTS 1684
            P    + + +M+  S  +T   + +  + S    T T    +A+       P  ST    
Sbjct: 223  P----SLSTSMVSASVASTSVASSSVASSSVAYSTQTCFCNVADRLY----PAGSTIYRH 274

Query: 1685 RSTSSPLTESTTLLSTLPPAIEMTSTAPPST--PTAPTTTSGGHTLSPPPSTTTSPPGTP 1742
            R  +     +  L S     +    +  PST  P AP T+    T S P +    P   P
Sbjct: 275  RDLAGHCYYA--LCSQDCQVVRGVDSDCPSTTLPPAPATSPSIST-SEPVTELGCPNAVP 331

Query: 1743 TRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVL--------- 1793
             R    G + A TP+  + T       +  P + P + + T    YP+  +         
Sbjct: 332  PR--KKGETWA-TPNCSEATCEGNNVISLRPRTCPRVEKPTCANGYPAVKVADQDGCCHH 388

Query: 1794 -----ICCVLNDTYYAPGEEVYNGTYGDTCYFV 1821
                 +C    D +Y   +  Y  T+ D C +V
Sbjct: 389  YQCQCVCSGWGDPHYITFDGTYY-TFLDNCTYV 420



 Score = 40.0 bits (92), Expect = 0.030
 Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 8/84 (9%)

Query: 1328 PTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---P 1384
            P  T STT  P TT+TT  P  TP+   T +TTP++ T+T   + + T    P T+   P
Sbjct: 45   PVPTTSTTSAP-TTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHP 103

Query: 1385 ITTTT----TVTPTPTPTGTQTPT 1404
            +   T       P+P P G    T
Sbjct: 104  LCAWTKWFDVDFPSPGPHGGDKET 127



 Score = 38.5 bits (88), Expect = 0.089
 Identities = 27/71 (38%), Positives = 38/71 (53%), Gaps = 6/71 (8%)

Query: 1726 HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGL 1785
            H L P P+T+T+    PT  TT+G  +  TPS V TT+T+  + T T  S  S+ +TT  
Sbjct: 41   HNLCPVPTTSTT--SAPTTSTTSGPGT--TPSPVPTTSTTPVSKTST--SHLSVSKTTHS 94

Query: 1786 RPYPSSVLICC 1796
            +P  S     C
Sbjct: 95   QPVTSDCHPLC 105



 Score = 37.7 bits (86), Expect = 0.15
 Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 1349 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTST-- 1406
            P PT   T TT+  TT+TT  P  TP+   T +TTP++ T+T   + + T    P ++  
Sbjct: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101

Query: 1407 -PITTTT----TVTPTPTPTGTQTPT 1427
             P+   T       P+P P G    T
Sbjct: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127



 Score = 37.7 bits (86), Expect = 0.15
 Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 10/86 (11%)

Query: 1372 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTT-- 1429
            P PT   T TT+  TT+TT  P  TP+   T ++TP++ T+T   + + T    P T+  
Sbjct: 45   PVPT---TSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDC 101

Query: 1430 -PITTTT----TVTPTPTPTGTQAPT 1450
             P+   T       P+P P G    T
Sbjct: 102  HPLCAWTKWFDVDFPSPGPHGGDKET 127



 Score = 36.2 bits (82), Expect = 0.44
 Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 10/87 (11%)

Query: 1416 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTT 1475
            P PT + T  PTT   +TT+    TP+P  T + TP + T+TS ++ + T T +Q  T+ 
Sbjct: 45   PVPTTSTTSAPTT---STTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKT-THSQPVTSD 100

Query: 1476 --PITTTT----TVTPTPTPTGTQTPT 1496
              P+   T       P+P P G    T
Sbjct: 101  CHPLCAWTKWFDVDFPSPGPHGGDKET 127



 Score = 35.8 bits (81), Expect = 0.58
 Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 3/61 (4%)

Query: 1330 STQSTTPTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTP--TGTQTPTTTPIT 1386
            S  +  P P T+TT+   T T +G   TP+  P T+TT V+ T T   + ++T  + P+T
Sbjct: 39   SQHNLCPVPTTSTTSAPTTSTTSGPGTTPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVT 98

Query: 1387 T 1387
            +
Sbjct: 99   S 99



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 11/68 (16%)

Query: 1284 CLNYEINVQCCECVTQPTTM--TTTTTENP--TPTPITTTTTVTPTPTPTSTQSTTPTPI 1339
            CL  + N+  C   T  TT   TT+TT  P  TP+P+ TT+T     TP S  ST+   +
Sbjct: 36   CLYSQHNL--CPVPTTSTTSAPTTSTTSGPGTTPSPVPTTST-----TPVSKTSTSHLSV 88

Query: 1340 TTTTTVTP 1347
            + TT   P
Sbjct: 89   SKTTHSQP 96



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 12/85 (14%)

Query: 1304 TTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTT--- 1360
            TT+TT  PT T  T+    TP+P PT    T+ TP++ T+T   + + T    P T+   
Sbjct: 48   TTSTTSAPT-TSTTSGPGTTPSPVPT----TSTTPVSKTSTSHLSVSKTTHSQPVTSDCH 102

Query: 1361 PITTTT----TVTPTPTPTGTQTPT 1381
            P+   T       P+P P G    T
Sbjct: 103  PLCAWTKWFDVDFPSPGPHGGDKET 127



 Score = 32.3 bits (72), Expect = 6.4
 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 1403 PTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTP 1462
            P  T  TT+   T T +  GT TP+  P T+TT V+ T T   + + T  +   TS   P
Sbjct: 45   PVPTTSTTSAPTTSTTSGPGT-TPSPVPTTSTTPVSKTSTSHLSVSKTTHSQPVTSDCHP 103


>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2852

 Score =  430 bits (1105), Expect = e-119
 Identities = 243/698 (34%), Positives = 377/698 (54%), Gaps = 39/698 (5%)

Query: 347  TVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQ 406
            +V+L  D ++ V + ++   +L ++ ++  P+   +F + R SS  + V   +GVR+   
Sbjct: 498  SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYD 557

Query: 407  LAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHD 466
                ++L++ +DQ       GLCG FNG   DDF +  G+ E+T   F N+WK  S+C  
Sbjct: 558  REG-LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP 616

Query: 467  KLDWLD-DPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNN 525
             +     DPC +++++A+Y+   CS+L  T   F  C + + P  Y+++C+ D C C   
Sbjct: 617  LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC--G 672

Query: 526  EDCLCAALSSYARACTAKGVML-WGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE 584
            + CLCA L+ YA  C   G+ + +  R   C     SC  S+ +   +  C +TC+ L+ 
Sbjct: 673  QPCLCATLAHYAHLCRRHGLPVDFRARLPACAL---SCEASKEYSPCVAPCGRTCQDLAS 729

Query: 585  ADSHCLEGFAP------VDGCGCPDHTFLDEKGR-CVPLAKCSCYHRGLYLEAGDVVVRQ 637
             ++  ++G         V+GC CP  T+LD +   CVP  +CSC+ +G+    GD  +  
Sbjct: 730  PEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 789

Query: 638  EERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNL-TALATSKPRALSCQTLAAGYY-HT 695
               C C+DG + C   R    +C A ++ ++CS+L T L  S+ R    Q L        
Sbjct: 790  LGHCHCKDGVMSCDS-RAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 848

Query: 696  ECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQA 755
             C+SGC CP GL+  G   C + +ECPC      Y  G ++   C+TC C+RG + CT  
Sbjct: 849  PCLSGCACPQGLLRHG-DACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 907

Query: 756  VCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGV 815
             C  TC+ YG  HY TFDG  +DF G C    V+     ++S  SFS+I ENV C ++G+
Sbjct: 908  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVSFSVIVENVNCYSSGM 962

Query: 816  TCSKAIKIFMGRTELKLEDK------HRVVIQRDEGHHVAYTTREVGQYLVVE-SSTGII 868
             C K I I +G + +  +D          +  + E H     T  VG + +V      I 
Sbjct: 963  ICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVH-----TWRVGFFTLVHFPQEHIT 1017

Query: 869  VIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC 928
            ++WD+RTTV ++  P ++G + GLCGNFD ++ N+  T +++ +++  +FG+SW  A  C
Sbjct: 1018 LLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA-AVEC 1076

Query: 929  PDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGD 988
            PD     + C LNP R  +A+K+CSIL S VF ICH  VD   FY  C+ D+C C  GGD
Sbjct: 1077 PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGD 1136

Query: 989  CECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1026
            CECFC++V++YA +C + G  V WRTP LCP  CD++N
Sbjct: 1137 CECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174



 Score =  239 bits (610), Expect = 3e-62
 Identities = 318/1356 (23%), Positives = 477/1356 (35%), Gaps = 232/1356 (17%)

Query: 1288 EINVQCC---ECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTT 1344
            E+  +C    +CV     + T    N T  P    +   PTP+    Q +  +P   T T
Sbjct: 1380 EVTQRCVYLEDCVEPAVWVPTEALGNETLPP----SQGLPTPSDEEPQLSQESP--RTPT 1433

Query: 1345 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1404
              P  TP    T    P   T T  P  +P  TQT    P+  T +  P      T++P 
Sbjct: 1434 HRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPLELTASQLPAGP---TESPA 1489

Query: 1405 STPITTTTTVTP-TPT----PTGTQTPT---------TTPITTTTTVTPTPTPTGTQAPT 1450
            S  +T +    P TP     P   QTPT         TT +T     +P  T +    P 
Sbjct: 1490 SKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPA 1549

Query: 1451 PTAITTTSTVT-----------PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ----TP 1495
            P     T  VT             P P+ T +P++ P+ +   ++ +PT +G+     TP
Sbjct: 1550 PRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTP 1609

Query: 1496 TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPT 1555
              T + + T V P PT   + +  STP+T   T          Q P  +P++T +     
Sbjct: 1610 AVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAE-------QVPV-SPLATRSLEIVL 1660

Query: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-VLITTTTTMTPTPTP------TSTK 1608
             T  G +   + P+ +  +  P P P+    P     + T +   P  TP      T+T 
Sbjct: 1661 STEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATD 1719

Query: 1609 STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAE 1668
                TP  +  +   +   +G    T +P++   T  P  TP     GP     T P+  
Sbjct: 1720 GLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP-----GPKASVITTPLQP 1774

Query: 1669 LTTSNP-------------------PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
              T+ P                   PP    P  + +    L  +T   S + P  E T+
Sbjct: 1775 QATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTA 1834

Query: 1710 TAPPSTPTAPTTTSGG---HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 1766
            +     P   TT         +S P S   S  G PT   T  +S   TP   +     A
Sbjct: 1835 SMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE-LTPATSHPLTPLVAEPEGAQA 1893

Query: 1767 WTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLS 1826
             T  P P S      +    P  S +++   L + +         GT             
Sbjct: 1894 GTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAH---------GTSAGPHLAAEPVDE 1944

Query: 1827 CTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWW 1886
             T E    S P+             T    +ST   P                       
Sbjct: 1945 ATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------------------- 1985

Query: 1887 LCDCFMATCKYNNTVEIVKVECEPPPM--PTCSNGLQPVRVEDPDGCCWHWECDCYCTGW 1944
              DC    C     + + + +  P     P C      VRV   D CC  WEC C C+ +
Sbjct: 1986 --DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIF 2042

Query: 1945 GDPHYVTFDGLYYSYQGNCTYVLVEEISPS-------VDNFGVYIDNYHCDPNDKVSCPR 1997
             D  +VTFDG + +      Y+L +  SP        +D     + + +  P     C  
Sbjct: 2043 PDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLDCKSANLGHLNWPP----FCLV 2096

Query: 1998 TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVL 2057
             L + H   +V I   +      +V V+ Q V  P  +YG  +  +G  Y++  P    +
Sbjct: 2097 MLNMTHLAHQVTIDRFNR-----KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQI 2151

Query: 2058 VSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA---DQWLVN 2114
               +     +            G CG C    ++D  L  G +V   E  A   D W V 
Sbjct: 2152 QWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVP 2211

Query: 2115 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYY 2174
                     SS T+       P    TT   DC  SP  +++ +  F+ CH  VPP+ + 
Sbjct: 2212 ---------SSLTSVGQTRFRPDSCATT---DC--SPCLRMVSNRTFSACHRFVPPESFC 2257

Query: 2175 DACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPA 2234
            +  + D+ ++      C +L  Y A+C + ++C++WR   +  C   C S   YQAC  A
Sbjct: 2258 ELWIRDTKYV---QQPCVALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTA 2312

Query: 2235 EEP--TCKSSS----SQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPRE 2286
             EP  TC+         ++  VL EGC C EGT+ +     +C+    C C     VPR 
Sbjct: 2313 CEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2372

Query: 2287 FGEHFEFDCKNCVC--LEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITV 2344
             GE +      C     +    I+     C       C+  G  +A  +   D CC  TV
Sbjct: 2373 LGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE-VALLLPTKDPCCLGTV 2431

Query: 2345 CKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCE-SKGVCVHGNAEYQPG------- 2396
            C CN +LC+     C  G  + +      CCP Y CE    +C    AE  P        
Sbjct: 2432 CVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLC---EAELVPSCRQDQIL 2488

Query: 2397 ---------SPVYSSKCQDC-----VCTD----KVDNNTL-----LNVIACTHVPC-NTS 2432
                        Y   C DC      C +     V  NT      L    C +  C    
Sbjct: 2489 ITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQ 2548

Query: 2433 CSPGFELME--APGECC--KKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKI 2488
            C  G  L+E  +P  CC  K CE   C               D  + P   C  +   ++
Sbjct: 2549 CGLGTALVEVWSPDRCCPYKSCE---C---------------DCDTIPVPRCHLWEKSQL 2590

Query: 2489 HNQLISSVSNIT-CPNFD---ASICIPGSITFMPNG 2520
              + + SV N+  C  ++   A +C+   +  M  G
Sbjct: 2591 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPG 2626



 Score =  231 bits (589), Expect = 7e-60
 Identities = 190/769 (24%), Positives = 312/769 (40%), Gaps = 164/769 (21%)

Query: 372  LQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGN 431
            ++V LPHV  S  + + + Y I+   +      +       +++ +     G   GLCGN
Sbjct: 158  MRVQLPHVMGSARLQQLAGYVIVRHQSA---FTLAWDGASAVYIKMSPELLGWTHGLCGN 214

Query: 432  FNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDD----PC-SLNIESANYAE 486
             N    DD  T+SG +      F ++W+ Q+               PC   N  +     
Sbjct: 215  NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274

Query: 487  HWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVM 546
              C  L +   PF  CH+ V P  +       T +C ++   LC ++           V 
Sbjct: 275  EQCEALLRP--PFDACHAYVSPLPF-------TASCTSD---LCQSMGD---------VA 313

Query: 547  LWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTF 606
             W                              CR+L+E    C +   P+ G        
Sbjct: 314  TW------------------------------CRALAEYARACAQAGRPLQGW------- 336

Query: 607  LDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIH 666
                                             R   R   +HC++       C A    
Sbjct: 337  ---------------------------------RTQLRQCTVHCKEKAFTYNECIA---- 359

Query: 667  MDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHN 726
                     A+  PRA    +  A      CV GC CP+GL+ +  GGCV   ECPC  +
Sbjct: 360  ------CCPASCHPRASCVDSEIA------CVDGCYCPNGLIFED-GGCVAPAECPCEFH 406

Query: 727  NDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYV 786
              LY  G+ +K DCNTCTC  G+W C+ AVC   CS+ G  H+ TFDG+ Y F   C Y+
Sbjct: 407  GTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYI 466

Query: 787  AVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRT-----------ELKLED 834
                   ++ S G+F++  +N PCG      C +++ + + +            ++ L D
Sbjct: 467  -----LAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFD 521

Query: 835  KHRVVIQRDEGHHVAYTTREVGQ-YLVVESSTGIIVIWDKR-TTVFIKLAPSYKGTVCGL 892
            +++++    +    A+  R +   +L V ++ G+ V++D+    +++++   +     GL
Sbjct: 522  QYKIIPPYTDD---AFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGL 578

Query: 893  CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC-PDVSTNP-EPCSLNPHRRSWAEK 950
            CG F+  + +DF +   +  S+   FGNSWK    C P VS +P +PC ++    S++ +
Sbjct: 579  CGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQ 638

Query: 951  QCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV 1010
             CS+L   +F+ C + + P P++E C  D+C C       C C+ +A YA  C + G  V
Sbjct: 639  ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPV 694

Query: 1011 FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTIN-----GIHSNISVS---YL 1061
             +R     C + C       E    Y PC      TC+ +      G+     +S    +
Sbjct: 695  DFRARLPACALSC-------EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 747

Query: 1062 EGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGAS-VPTEETC 1109
            EGC   CP D  + +     CV  ++C C+ +   YPPG S +P+   C
Sbjct: 748  EGC--ACPPDTYL-DTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 793



 Score =  157 bits (398), Expect = 1e-37
 Identities = 125/396 (31%), Positives = 180/396 (45%), Gaps = 40/396 (10%)

Query: 761  CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG-SFSIITENVP-CGTTGVTCS 818
            C  +G  H  TFDG YY   G  SY  V    G++   G SFSI   N P CG++  TCS
Sbjct: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 134

Query: 819  KAIKIF-MGRTELKLEDKHRVVIQRDEGHHVAYTTR--EVGQYLVVESSTGIIVIWDKRT 875
            +A+ +F +G  E+ L  +      R +  HV  + R  ++  Y++V   +   + WD  +
Sbjct: 135  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 194

Query: 876  TVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE----APTCPDV 931
             V+IK++P   G   GLCGN +    +D  T    +    ++F +SW+E     P  P  
Sbjct: 195  AVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTT 254

Query: 932  STNPEPCSL--NPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC 989
            S+ P P  L  NP       +QC  L    F  CH+ V P PF  +C  D   C + GD 
Sbjct: 255  SSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LCQSMGDV 312

Query: 990  ECFCSAVASYAQECTKEGACV-FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1047
              +C A+A YA+ C + G  +  WRT    C + C       E  + Y  C      +C 
Sbjct: 313  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC------KEKAFTYNECIACCPASCH 366

Query: 1048 TINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEE 1107
                   +  ++ ++GCY  CP    I+E+    CV   +C C    T YPPG+ V  +E
Sbjct: 367  P-RASCVDSEIACVDGCY--CPNGL-IFEDG--GCVAPAECPCEFHGTLYPPGSVV--KE 418

Query: 1108 TCKSCVCTNS----SQVVCRPE---EGKILNQTQDG 1136
             C +C CT+     S  VC  E    G I   T DG
Sbjct: 419  DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 454



 Score =  119 bits (297), Expect = 5e-26
 Identities = 139/580 (23%), Positives = 226/580 (38%), Gaps = 108/580 (18%)

Query: 1895 CKYNNTV----EIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECD-----CYCTGWG 1945
            C+++ T+     +VK +C      TC++G               WEC        C+  G
Sbjct: 403  CEFHGTLYPPGSVVKEDCNTC---TCTSG--------------KWECSTAVCPAECSVTG 445

Query: 1946 DPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTL-IVRHE 2004
            D H+ TFDG  Y++   C Y+L +  S S   F V + N  C  N   +C +++ ++ H+
Sbjct: 446  DIHFTTFDGRRYTFPATCQYILAK--SRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 503

Query: 2005 TQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN--G 2062
                  + V +      +  ++  +  PY     E+ +    ++     +GV V Y+  G
Sbjct: 504  DPR---RQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560

Query: 2063 LSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCP 2122
            L   +++   R+  +T G CGT    T DD + P G   S  +   + W       P   
Sbjct: 561  LRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV- 618

Query: 2123 HSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC 2182
             S S      V +     +           C ++   +FA C A + P  Y++ C  D+C
Sbjct: 619  -SGSPLDPCDVHLQAASYSV--------QACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669

Query: 2183 FMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 2242
               G    CA+L  YA LC +  + +D+R     AC + C + +EY  C      TC+  
Sbjct: 670  -RCGQPCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPCGRTCQDL 727

Query: 2243 SSQQ----------NNTVLVEGCFCPEGTMNYAPGFDVCV--KTCGC--VGPDNVPREFG 2288
            +S +          +    VEGC CP  T       D+CV    C C   G D  P   G
Sbjct: 728  ASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-DLCVPRNQCSCHFQGVDYPP---G 783

Query: 2289 EHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCN 2348
            +       +C C +G   + C     S+ P   C     +    VN +D   ++ + +  
Sbjct: 784  DSDIPSLGHCHCKDG--VMSCD----SRAPAAACPAGQVF----VNCSDLHTDLELSRER 833

Query: 2349 TSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA--------------EYQ 2394
            T  C+++  +  L    +   + G  CP      +G+  HG+A              EY 
Sbjct: 834  T--CEQQ--LLNLSVSARGPCLSGCACP------QGLLRHGDACFLPEECPCTWKGKEYF 883

Query: 2395 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434
            PG  V  S C  CVC              CT  PC ++C+
Sbjct: 884  PGDQV-MSPCHTCVCQ--------RGSFQCTLHPCASTCT 914



 Score =  115 bits (289), Expect = 4e-25
 Identities = 109/399 (27%), Positives = 155/399 (38%), Gaps = 49/399 (12%)

Query: 1936 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 1995
            E D  C  WG  H  TFDGLYY   G  +Y LV    P   +F + + N     +   +C
Sbjct: 74   ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 133

Query: 1996 PR--TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE 2053
             R  +L    E +  L K V    M+VQ         LP+   G    Q    YV+   +
Sbjct: 134  SRAVSLFFVGEQEIHLAKEVTHGGMRVQ---------LPH-VMGSARLQQLAGYVIVRHQ 183

Query: 2054 LGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV 2113
                ++++G S             T G CG       DD +  SG++  +       W  
Sbjct: 184  SAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE 243

Query: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHY 2173
              P++P  P +SS  + P +    G     ++       C+ +    F  CHA V P  +
Sbjct: 244  QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRPPFDACHAYVSPLPF 297

Query: 2174 YDACVFDSCFMPGS-SLECASLQAYAALCAQQNICLD-WRNHTHGACLVECP----SHRE 2227
              +C  D C   G  +  C +L  YA  CAQ    L  WR      C V C     ++ E
Sbjct: 298  TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNE 356

Query: 2228 YQACGPAEEPTCKSSSSQQNNTV-LVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 2286
              AC PA   +C   +S  ++ +  V+GC+CP G         +  +  GCV P   P E
Sbjct: 357  CIACCPA---SCHPRASCVDSEIACVDGCYCPNG---------LIFEDGGCVAPAECPCE 404

Query: 2287 F-------GEHFEFDCKNCVCLEGG---SGIICQPKRCS 2315
            F       G   + DC  C C  G    S  +C P  CS
Sbjct: 405  FHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC-PAECS 442



 Score =  109 bits (273), Expect = 3e-23
 Identities = 91/329 (27%), Positives = 145/329 (44%), Gaps = 32/329 (9%)

Query: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGP-GQAEAPAGVESIL 95
           CS  G+ H+ TFDG  + FP  C Y  A     S   F V L+  P G  +  A V+S+ 
Sbjct: 441 CSVTGDIHFTTFDGRRYTFPATCQYILAKS--RSSGTFTVTLQNAPCGLNQDGACVQSVS 498

Query: 96  LTIKDD-----TIYLTRHLAVLNGAVVSTPHYSPGLLIEK-SDAYTKVYSRAGLTLMWNR 149
           + +  D     T+     + + +   +  P+      I + S  + +V +  G+ ++++R
Sbjct: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558

Query: 150 ED-ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSD-GVLFS-PLEFGNMQKINQ--PDV 204
           E   L L++D ++   T GLCG +NG  +  +FLS  GV  S P  FGN  K       +
Sbjct: 559 EGLRLYLQVDQRWVEDTVGLCGTFNG-NTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 617

Query: 205 VCEDPEEEV-APASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
           V   P +        + +  +   +LT E FA C   +   PY   C++D CRC  G  C
Sbjct: 618 VSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRC--GQPC 675

Query: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323
           +C+T+A ++  C    G P ++R    A  P  + +C  +  Y    +PC  TC  L   
Sbjct: 676 LCATLAHYAHLC-RRHGLPVDFR----ARLPACALSCEASKEYSPCVAPCGRTCQDLASP 730

Query: 324 SLC---------EEHRMDGCFCPEGAQAD 343
             C          +  ++GC CP     D
Sbjct: 731 EACGVDGGDDLSRDECVEGCACPPDTYLD 759



 Score =  102 bits (255), Expect = 4e-21
 Identities = 154/720 (21%), Positives = 244/720 (33%), Gaps = 105/720 (14%)

Query: 1031 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1090
            CEW Y+ C +  F+TCR      S   V  +EGC P CP  + + +E  ++CV  + C  
Sbjct: 1336 CEWRYDACASPCFQTCRDPRAA-SCRDVPRVEGCVPVCPTPQ-VLDEVTQRCVYLEDC-- 1391

Query: 1091 YVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1150
                    P   VPTE      +  +        EE + L+Q       +     P   +
Sbjct: 1392 ------VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQ-LSQESPRTPTHRPALTPAAPL 1444

Query: 1151 EKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSS----------TVLSTTP 1200
                N     T    ++   T T    P   T +     PT S            +  TP
Sbjct: 1445 TTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1504

Query: 1201 KLCCLWSDWINEDHPSSGSDDGDRETFDGV---CGAPE-DIECRSVKDPHLSLEQLGQKV 1256
            +   L    +    P+ G   G  ET        G+P   +  RS   P           
Sbjct: 1505 ESSSL---PVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFP-------- 1553

Query: 1257 QLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPI 1316
                     L+ K    +  G +P+                 + T    + T +P+  P+
Sbjct: 1554 ---------LMTKAVTVRGHGSLPV-----------------RTTPPQPSLTASPSSRPV 1587

Query: 1317 TTTTTVTPTPTPTSTQSTTPTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1373
             +   ++ +PT + +     TP  T   + T  P PT   + +  +TP+T   T      
Sbjct: 1588 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGT------ 1641

Query: 1374 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTT-TPIT 1432
                Q P  +P+ T +      T  G +   S P+ +  +  P P P+    P   T + 
Sbjct: 1642 -AAEQVP-VSPLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMA 1698

Query: 1433 TTTTVTPTPTP------TGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPT 1486
            T +   P  TP      T T     T   +  +  P+   +G    T+ P+    T  P 
Sbjct: 1699 TRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAP- 1757

Query: 1487 PTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPI 1546
                   TP P A   TT + P          T+ P  T + V P      TQ   PT I
Sbjct: 1758 -----VATPGPKASVITTPLQP--------QATTLPAQTLSPVLPFTPAAMTQAHPPTHI 1804

Query: 1547 STTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP 1604
            +     T      G   PT+   P+   T    +  P  + T    +++   ++ PT   
Sbjct: 1805 APPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSL-PTSMY 1863

Query: 1605 TSTKS--TTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTS 1662
             S +   T +TP T+         P G Q  T +P+ T+  ++     T           
Sbjct: 1864 GSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDS--MLVL 1921

Query: 1663 TAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST---LPPAIEMTSTAPPSTPTAP 1719
               +AE   ++  P  +      +T+ P   S   LS    L  A+  T+ A  ST   P
Sbjct: 1922 LPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 78/317 (24%), Positives = 124/317 (39%), Gaps = 18/317 (5%)

Query: 35  NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
           ++C  WG  H +TFDG  +   G   Y          + F++ +   P    +P      
Sbjct: 77  SICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRA 136

Query: 95  --LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152
             L  + +  I+L + +    G  V  PH      +++   Y  V  ++  TL W+   A
Sbjct: 137 VSLFFVGEQEIHLAKEVTH-GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASA 195

Query: 153 LMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNM---QKINQP-----D 203
           + +++  +    T GLCG+ N         S G L   + EF +    Q  NQP      
Sbjct: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255

Query: 204 VVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
            +   P  +  P +      +CE LL    F  C   V   P+  +C  D C+  G    
Sbjct: 256 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 314

Query: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323
            C  +AE++R C+ AG     WRT     +    +       Y E  + C  +C H   S
Sbjct: 315 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKA---FTYNECIACCPASC-HPRAS 370

Query: 324 SLCEEHR-MDGCFCPEG 339
            +  E   +DGC+CP G
Sbjct: 371 CVDSEIACVDGCYCPNG 387



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 70/313 (22%), Positives = 118/313 (37%), Gaps = 46/313 (14%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C    C   CT +GD HY TFDGL + + G C   LV+  S S  +F V ++N +C  + 
Sbjct: 904  CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK--STSDVSFSVIVENVNCYSSG 961

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
             + C + + +      ++       P       ++Q V           ++ G   +V  
Sbjct: 962  MI-CRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEV---------HTWRVGFFTLVHF 1011

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 2111
            P+  + + ++  +        ++     G CG     T ++   P    ++N +     W
Sbjct: 1012 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1071

Query: 2112 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL--------CQLIKDSLFAQ 2163
               +     CP +                  P   C  +PL        C ++   +F  
Sbjct: 1072 AAVE-----CPDTLD----------------PRDMCVLNPLREPFAKKECSILLSEVFEI 1110

Query: 2164 CHALVPPQHYYDACVFDSC-FMPGSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLV 2220
            CH +V    +Y  C+ D+C    G   EC  AS+ AYA  C Q  + +DWR  T   C  
Sbjct: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLCPY 1168

Query: 2221 ECPSHREYQACGP 2233
            +C    +    GP
Sbjct: 1169 DCDFFNKVLGKGP 1181



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 89/398 (22%), Positives = 145/398 (36%), Gaps = 67/398 (16%)

Query: 752  CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY----------CGQNSSLGS- 800
            C    C   CSI+    ++TFDG +        Y+  Q            C ++++LG  
Sbjct: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHL 2088

Query: 801  ----FSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVG 856
                F ++  N+    T +     I  F  +  + L+     V +        +   + G
Sbjct: 2089 NWPPFCLVMLNM----THLAHQVTIDRFNRKVTVDLQPVWPPVSR------YGFRIEDTG 2138

Query: 857  QYLVVESSTGIIVIW-DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSE 915
               ++ + + I + W      + ++ + + K    GLCG  D  + ND T +D  VV   
Sbjct: 2139 HMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGA 2198

Query: 916  LD---FGNSWKEAPTCPDVSTN---PEPCSLNPHRRSWAEKQCS----ILKSSVFSICHS 965
             D   F +SW+   +   V      P+ C         A   CS    ++ +  FS CH 
Sbjct: 2199 EDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHR 2249

Query: 966  KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYY 1025
             V P+ F E  + D+            C A+  Y   C K   C+ WR  D CP  C   
Sbjct: 2250 FVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2303

Query: 1026 NPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYL----EGCYPRCPKDRPIYEEDLKK 1081
            +    C    EP      +TC+  +GI   +   +     EGC   C +   ++      
Sbjct: 2304 STYQACVTACEPP-----KTCQ--DGILGPLDPEHCQVLGEGCV--CSEGTILHRRHSAL 2354

Query: 1082 CVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQ 1119
            C+   KC C   D+   P A   T  +  S  C +  Q
Sbjct: 2355 CIPEAKCAC--TDSMGVPRALGETWNSSLSGCCQHQCQ 2390



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 66/274 (24%), Positives = 120/274 (43%), Gaps = 43/274 (15%)

Query: 35   NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
            + C+ +G+ HY+TFDG  F F G C                VHL +          VE++
Sbjct: 911  STCTAYGDRHYRTFDGLPFDFVGACK---------------VHLVKSTSDVSFSVIVENV 955

Query: 95   ------LLTIKDDTIYLTRHLAVLNGAVVSTPHYSP-GLLIEKSDAYT--------KVYS 139
                  ++  K  +I +   L V +     + + SP   L +K + +T          + 
Sbjct: 956  NCYSSGMICRKFISINVGNSLIVFDD---DSGNPSPESFLDDKQEVHTWRVGFFTLVHFP 1012

Query: 140  RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDG--VLFSPLEFGNM- 196
            +  +TL+W++   + ++   +++    GLCG+++ L++ +E  +     L +P EFG+  
Sbjct: 1013 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFD-LKTINEMRTPENLELTNPQEFGSSW 1071

Query: 197  QKINQPDVVCEDPEEEVAPASCSEHRAECE-RLLTAEAFADCQDLVPLEPYLRACQQDRC 255
              +  PD +  DP +        E  A+ E  +L +E F  C  +V +  +   C  D C
Sbjct: 1072 AAVECPDTL--DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTC 1129

Query: 256  RCPGGD--TCVCSTVAEFSRQCSHAGGRPGNWRT 287
             C  G    C C++V+ ++ QC   G    +WRT
Sbjct: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRT 1162



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 59/226 (26%), Positives = 84/226 (37%), Gaps = 39/226 (17%)

Query: 413  LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATG---AGFANTWKAQSSCHD--K 467
            + V   + S+ Q  GLCG  +G   +D     G V       A F ++W+  SS     +
Sbjct: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219

Query: 468  LDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNED 527
              +  D C+    S       C  +    T F  CH  V P  + +    DT   Q    
Sbjct: 2220 TRFRPDSCATTDCSP------CLRMVSNRT-FSACHRFVPPESFCELWIRDTKYVQQP-- 2270

Query: 528  CLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADS 587
              C AL+ Y   C    V +  WR          CP    FL +  +  Q C +  E   
Sbjct: 2271 --CVALTVYVAMCHKFHVCI-EWRRS------DYCP----FLCSSDSTYQACVTACEPPK 2317

Query: 588  HCLEGF-APVD---------GCGCPDHTFLDEK--GRCVPLAKCSC 621
             C +G   P+D         GC C + T L  +    C+P AKC+C
Sbjct: 2318 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363


>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2924

 Score =  430 bits (1105), Expect = e-119
 Identities = 243/698 (34%), Positives = 377/698 (54%), Gaps = 39/698 (5%)

Query: 347  TVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQ 406
            +V+L  D ++ V + ++   +L ++ ++  P+   +F + R SS  + V   +GVR+   
Sbjct: 570  SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYD 629

Query: 407  LAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHD 466
                ++L++ +DQ       GLCG FNG   DDF +  G+ E+T   F N+WK  S+C  
Sbjct: 630  REG-LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP 688

Query: 467  KLDWLD-DPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNN 525
             +     DPC +++++A+Y+   CS+L  T   F  C + + P  Y+++C+ D C C   
Sbjct: 689  LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC--G 744

Query: 526  EDCLCAALSSYARACTAKGVML-WGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE 584
            + CLCA L+ YA  C   G+ + +  R   C     SC  S+ +   +  C +TC+ L+ 
Sbjct: 745  QPCLCATLAHYAHLCRRHGLPVDFRARLPACAL---SCEASKEYSPCVAPCGRTCQDLAS 801

Query: 585  ADSHCLEGFAP------VDGCGCPDHTFLDEKGR-CVPLAKCSCYHRGLYLEAGDVVVRQ 637
             ++  ++G         V+GC CP  T+LD +   CVP  +CSC+ +G+    GD  +  
Sbjct: 802  PEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 861

Query: 638  EERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNL-TALATSKPRALSCQTLAAGYY-HT 695
               C C+DG + C   R    +C A ++ ++CS+L T L  S+ R    Q L        
Sbjct: 862  LGHCHCKDGVMSCDS-RAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 920

Query: 696  ECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQA 755
             C+SGC CP GL+  G   C + +ECPC      Y  G ++   C+TC C+RG + CT  
Sbjct: 921  PCLSGCACPQGLLRHG-DACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 979

Query: 756  VCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGV 815
             C  TC+ YG  HY TFDG  +DF G C    V+     ++S  SFS+I ENV C ++G+
Sbjct: 980  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVSFSVIVENVNCYSSGM 1034

Query: 816  TCSKAIKIFMGRTELKLEDK------HRVVIQRDEGHHVAYTTREVGQYLVVE-SSTGII 868
             C K I I +G + +  +D          +  + E H     T  VG + +V      I 
Sbjct: 1035 ICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVH-----TWRVGFFTLVHFPQEHIT 1089

Query: 869  VIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC 928
            ++WD+RTTV ++  P ++G + GLCGNFD ++ N+  T +++ +++  +FG+SW  A  C
Sbjct: 1090 LLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA-AVEC 1148

Query: 929  PDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGD 988
            PD     + C LNP R  +A+K+CSIL S VF ICH  VD   FY  C+ D+C C  GGD
Sbjct: 1149 PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGD 1208

Query: 989  CECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1026
            CECFC++V++YA +C + G  V WRTP LCP  CD++N
Sbjct: 1209 CECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1246



 Score =  239 bits (610), Expect = 3e-62
 Identities = 318/1356 (23%), Positives = 477/1356 (35%), Gaps = 232/1356 (17%)

Query: 1288 EINVQCC---ECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTT 1344
            E+  +C    +CV     + T    N T  P    +   PTP+    Q +  +P   T T
Sbjct: 1452 EVTQRCVYLEDCVEPAVWVPTEALGNETLPP----SQGLPTPSDEEPQLSQESP--RTPT 1505

Query: 1345 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1404
              P  TP    T    P   T T  P  +P  TQT    P+  T +  P      T++P 
Sbjct: 1506 HRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPLELTASQLPAGP---TESPA 1561

Query: 1405 STPITTTTTVTP-TPT----PTGTQTPT---------TTPITTTTTVTPTPTPTGTQAPT 1450
            S  +T +    P TP     P   QTPT         TT +T     +P  T +    P 
Sbjct: 1562 SKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPA 1621

Query: 1451 PTAITTTSTVT-----------PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ----TP 1495
            P     T  VT             P P+ T +P++ P+ +   ++ +PT +G+     TP
Sbjct: 1622 PRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTP 1681

Query: 1496 TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPT 1555
              T + + T V P PT   + +  STP+T   T          Q P  +P++T +     
Sbjct: 1682 AVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAE-------QVPV-SPLATRSLEIVL 1732

Query: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-VLITTTTTMTPTPTP------TSTK 1608
             T  G +   + P+ +  +  P P P+    P     + T +   P  TP      T+T 
Sbjct: 1733 STEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATD 1791

Query: 1609 STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAE 1668
                TP  +  +   +   +G    T +P++   T  P  TP     GP     T P+  
Sbjct: 1792 GLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP-----GPKASVITTPLQP 1846

Query: 1669 LTTSNP-------------------PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
              T+ P                   PP    P  + +    L  +T   S + P  E T+
Sbjct: 1847 QATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTA 1906

Query: 1710 TAPPSTPTAPTTTSGG---HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 1766
            +     P   TT         +S P S   S  G PT   T  +S   TP   +     A
Sbjct: 1907 SMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE-LTPATSHPLTPLVAEPEGAQA 1965

Query: 1767 WTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLS 1826
             T  P P S      +    P  S +++   L + +         GT             
Sbjct: 1966 GTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAH---------GTSAGPHLAAEPVDE 2016

Query: 1827 CTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWW 1886
             T E    S P+             T    +ST   P                       
Sbjct: 2017 ATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------------------- 2057

Query: 1887 LCDCFMATCKYNNTVEIVKVECEPPPM--PTCSNGLQPVRVEDPDGCCWHWECDCYCTGW 1944
              DC    C     + + + +  P     P C      VRV   D CC  WEC C C+ +
Sbjct: 2058 --DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIF 2114

Query: 1945 GDPHYVTFDGLYYSYQGNCTYVLVEEISPS-------VDNFGVYIDNYHCDPNDKVSCPR 1997
             D  +VTFDG + +      Y+L +  SP        +D     + + +  P     C  
Sbjct: 2115 PDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLDCKSANLGHLNWPP----FCLV 2168

Query: 1998 TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVL 2057
             L + H   +V I   +      +V V+ Q V  P  +YG  +  +G  Y++  P    +
Sbjct: 2169 MLNMTHLAHQVTIDRFNR-----KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQI 2223

Query: 2058 VSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA---DQWLVN 2114
               +     +            G CG C    ++D  L  G +V   E  A   D W V 
Sbjct: 2224 QWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVP 2283

Query: 2115 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYY 2174
                     SS T+       P    TT   DC  SP  +++ +  F+ CH  VPP+ + 
Sbjct: 2284 ---------SSLTSVGQTRFRPDSCATT---DC--SPCLRMVSNRTFSACHRFVPPESFC 2329

Query: 2175 DACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPA 2234
            +  + D+ ++      C +L  Y A+C + ++C++WR   +  C   C S   YQAC  A
Sbjct: 2330 ELWIRDTKYV---QQPCVALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTA 2384

Query: 2235 EEP--TCKSSS----SQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPRE 2286
             EP  TC+         ++  VL EGC C EGT+ +     +C+    C C     VPR 
Sbjct: 2385 CEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2444

Query: 2287 FGEHFEFDCKNCVC--LEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITV 2344
             GE +      C     +    I+     C       C+  G  +A  +   D CC  TV
Sbjct: 2445 LGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE-VALLLPTKDPCCLGTV 2503

Query: 2345 CKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCE-SKGVCVHGNAEYQPG------- 2396
            C CN +LC+     C  G  + +      CCP Y CE    +C    AE  P        
Sbjct: 2504 CVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLC---EAELVPSCRQDQIL 2560

Query: 2397 ---------SPVYSSKCQDC-----VCTD----KVDNNTL-----LNVIACTHVPC-NTS 2432
                        Y   C DC      C +     V  NT      L    C +  C    
Sbjct: 2561 ITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQ 2620

Query: 2433 CSPGFELME--APGECC--KKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKI 2488
            C  G  L+E  +P  CC  K CE   C               D  + P   C  +   ++
Sbjct: 2621 CGLGTALVEVWSPDRCCPYKSCE---C---------------DCDTIPVPRCHLWEKSQL 2662

Query: 2489 HNQLISSVSNIT-CPNFD---ASICIPGSITFMPNG 2520
              + + SV N+  C  ++   A +C+   +  M  G
Sbjct: 2663 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPG 2698



 Score =  231 bits (589), Expect = 7e-60
 Identities = 190/769 (24%), Positives = 312/769 (40%), Gaps = 164/769 (21%)

Query: 372  LQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGN 431
            ++V LPHV  S  + + + Y I+   +      +       +++ +     G   GLCGN
Sbjct: 230  MRVQLPHVMGSARLQQLAGYVIVRHQSA---FTLAWDGASAVYIKMSPELLGWTHGLCGN 286

Query: 432  FNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDD----PC-SLNIESANYAE 486
             N    DD  T+SG +      F ++W+ Q+               PC   N  +     
Sbjct: 287  NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346

Query: 487  HWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVM 546
              C  L +   PF  CH+ V P  +       T +C ++   LC ++           V 
Sbjct: 347  EQCEALLRP--PFDACHAYVSPLPF-------TASCTSD---LCQSMGD---------VA 385

Query: 547  LWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTF 606
             W                              CR+L+E    C +   P+ G        
Sbjct: 386  TW------------------------------CRALAEYARACAQAGRPLQGW------- 408

Query: 607  LDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIH 666
                                             R   R   +HC++       C A    
Sbjct: 409  ---------------------------------RTQLRQCTVHCKEKAFTYNECIA---- 431

Query: 667  MDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHN 726
                     A+  PRA    +  A      CV GC CP+GL+ +  GGCV   ECPC  +
Sbjct: 432  ------CCPASCHPRASCVDSEIA------CVDGCYCPNGLIFED-GGCVAPAECPCEFH 478

Query: 727  NDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYV 786
              LY  G+ +K DCNTCTC  G+W C+ AVC   CS+ G  H+ TFDG+ Y F   C Y+
Sbjct: 479  GTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYI 538

Query: 787  AVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRT-----------ELKLED 834
                   ++ S G+F++  +N PCG      C +++ + + +            ++ L D
Sbjct: 539  -----LAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFD 593

Query: 835  KHRVVIQRDEGHHVAYTTREVGQ-YLVVESSTGIIVIWDKR-TTVFIKLAPSYKGTVCGL 892
            +++++    +    A+  R +   +L V ++ G+ V++D+    +++++   +     GL
Sbjct: 594  QYKIIPPYTDD---AFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGL 650

Query: 893  CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC-PDVSTNP-EPCSLNPHRRSWAEK 950
            CG F+  + +DF +   +  S+   FGNSWK    C P VS +P +PC ++    S++ +
Sbjct: 651  CGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQ 710

Query: 951  QCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV 1010
             CS+L   +F+ C + + P P++E C  D+C C       C C+ +A YA  C + G  V
Sbjct: 711  ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPV 766

Query: 1011 FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTIN-----GIHSNISVS---YL 1061
             +R     C + C       E    Y PC      TC+ +      G+     +S    +
Sbjct: 767  DFRARLPACALSC-------EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 819

Query: 1062 EGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGAS-VPTEETC 1109
            EGC   CP D  + +     CV  ++C C+ +   YPPG S +P+   C
Sbjct: 820  EGC--ACPPDTYL-DTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 865



 Score =  157 bits (398), Expect = 1e-37
 Identities = 125/396 (31%), Positives = 180/396 (45%), Gaps = 40/396 (10%)

Query: 761  CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG-SFSIITENVP-CGTTGVTCS 818
            C  +G  H  TFDG YY   G  SY  V    G++   G SFSI   N P CG++  TCS
Sbjct: 151  CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 206

Query: 819  KAIKIF-MGRTELKLEDKHRVVIQRDEGHHVAYTTR--EVGQYLVVESSTGIIVIWDKRT 875
            +A+ +F +G  E+ L  +      R +  HV  + R  ++  Y++V   +   + WD  +
Sbjct: 207  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 266

Query: 876  TVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE----APTCPDV 931
             V+IK++P   G   GLCGN +    +D  T    +    ++F +SW+E     P  P  
Sbjct: 267  AVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTT 326

Query: 932  STNPEPCSL--NPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC 989
            S+ P P  L  NP       +QC  L    F  CH+ V P PF  +C  D   C + GD 
Sbjct: 327  SSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LCQSMGDV 384

Query: 990  ECFCSAVASYAQECTKEGACV-FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1047
              +C A+A YA+ C + G  +  WRT    C + C       E  + Y  C      +C 
Sbjct: 385  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC------KEKAFTYNECIACCPASCH 438

Query: 1048 TINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEE 1107
                   +  ++ ++GCY  CP    I+E+    CV   +C C    T YPPG+ V  +E
Sbjct: 439  P-RASCVDSEIACVDGCY--CPNGL-IFEDG--GCVAPAECPCEFHGTLYPPGSVV--KE 490

Query: 1108 TCKSCVCTNS----SQVVCRPE---EGKILNQTQDG 1136
             C +C CT+     S  VC  E    G I   T DG
Sbjct: 491  DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 526



 Score =  119 bits (297), Expect = 5e-26
 Identities = 139/580 (23%), Positives = 226/580 (38%), Gaps = 108/580 (18%)

Query: 1895 CKYNNTV----EIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECD-----CYCTGWG 1945
            C+++ T+     +VK +C      TC++G               WEC        C+  G
Sbjct: 475  CEFHGTLYPPGSVVKEDCNTC---TCTSG--------------KWECSTAVCPAECSVTG 517

Query: 1946 DPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTL-IVRHE 2004
            D H+ TFDG  Y++   C Y+L +  S S   F V + N  C  N   +C +++ ++ H+
Sbjct: 518  DIHFTTFDGRRYTFPATCQYILAK--SRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 575

Query: 2005 TQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN--G 2062
                  + V +      +  ++  +  PY     E+ +    ++     +GV V Y+  G
Sbjct: 576  DPR---RQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632

Query: 2063 LSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCP 2122
            L   +++   R+  +T G CGT    T DD + P G   S  +   + W       P   
Sbjct: 633  LRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV- 690

Query: 2123 HSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC 2182
             S S      V +     +           C ++   +FA C A + P  Y++ C  D+C
Sbjct: 691  -SGSPLDPCDVHLQAASYSV--------QACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 741

Query: 2183 FMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 2242
               G    CA+L  YA LC +  + +D+R     AC + C + +EY  C      TC+  
Sbjct: 742  -RCGQPCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPCGRTCQDL 799

Query: 2243 SSQQ----------NNTVLVEGCFCPEGTMNYAPGFDVCV--KTCGC--VGPDNVPREFG 2288
            +S +          +    VEGC CP  T       D+CV    C C   G D  P   G
Sbjct: 800  ASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-DLCVPRNQCSCHFQGVDYPP---G 855

Query: 2289 EHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCN 2348
            +       +C C +G   + C     S+ P   C     +    VN +D   ++ + +  
Sbjct: 856  DSDIPSLGHCHCKDG--VMSCD----SRAPAAACPAGQVF----VNCSDLHTDLELSRER 905

Query: 2349 TSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA--------------EYQ 2394
            T  C+++  +  L    +   + G  CP      +G+  HG+A              EY 
Sbjct: 906  T--CEQQ--LLNLSVSARGPCLSGCACP------QGLLRHGDACFLPEECPCTWKGKEYF 955

Query: 2395 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434
            PG  V  S C  CVC              CT  PC ++C+
Sbjct: 956  PGDQV-MSPCHTCVCQ--------RGSFQCTLHPCASTCT 986



 Score =  115 bits (289), Expect = 4e-25
 Identities = 109/399 (27%), Positives = 155/399 (38%), Gaps = 49/399 (12%)

Query: 1936 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 1995
            E D  C  WG  H  TFDGLYY   G  +Y LV    P   +F + + N     +   +C
Sbjct: 146  ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 205

Query: 1996 PR--TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE 2053
             R  +L    E +  L K V    M+VQ         LP+   G    Q    YV+   +
Sbjct: 206  SRAVSLFFVGEQEIHLAKEVTHGGMRVQ---------LPH-VMGSARLQQLAGYVIVRHQ 255

Query: 2054 LGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV 2113
                ++++G S             T G CG       DD +  SG++  +       W  
Sbjct: 256  SAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE 315

Query: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHY 2173
              P++P  P +SS  + P +    G     ++       C+ +    F  CHA V P  +
Sbjct: 316  QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRPPFDACHAYVSPLPF 369

Query: 2174 YDACVFDSCFMPGS-SLECASLQAYAALCAQQNICLD-WRNHTHGACLVECP----SHRE 2227
              +C  D C   G  +  C +L  YA  CAQ    L  WR      C V C     ++ E
Sbjct: 370  TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNE 428

Query: 2228 YQACGPAEEPTCKSSSSQQNNTV-LVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 2286
              AC PA   +C   +S  ++ +  V+GC+CP G         +  +  GCV P   P E
Sbjct: 429  CIACCPA---SCHPRASCVDSEIACVDGCYCPNG---------LIFEDGGCVAPAECPCE 476

Query: 2287 F-------GEHFEFDCKNCVCLEGG---SGIICQPKRCS 2315
            F       G   + DC  C C  G    S  +C P  CS
Sbjct: 477  FHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC-PAECS 514



 Score =  109 bits (273), Expect = 3e-23
 Identities = 91/329 (27%), Positives = 145/329 (44%), Gaps = 32/329 (9%)

Query: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGP-GQAEAPAGVESIL 95
           CS  G+ H+ TFDG  + FP  C Y  A     S   F V L+  P G  +  A V+S+ 
Sbjct: 513 CSVTGDIHFTTFDGRRYTFPATCQYILAKS--RSSGTFTVTLQNAPCGLNQDGACVQSVS 570

Query: 96  LTIKDD-----TIYLTRHLAVLNGAVVSTPHYSPGLLIEK-SDAYTKVYSRAGLTLMWNR 149
           + +  D     T+     + + +   +  P+      I + S  + +V +  G+ ++++R
Sbjct: 571 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630

Query: 150 ED-ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSD-GVLFS-PLEFGNMQKINQ--PDV 204
           E   L L++D ++   T GLCG +NG  +  +FLS  GV  S P  FGN  K       +
Sbjct: 631 EGLRLYLQVDQRWVEDTVGLCGTFNG-NTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 689

Query: 205 VCEDPEEEV-APASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
           V   P +        + +  +   +LT E FA C   +   PY   C++D CRC  G  C
Sbjct: 690 VSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRC--GQPC 747

Query: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323
           +C+T+A ++  C    G P ++R    A  P  + +C  +  Y    +PC  TC  L   
Sbjct: 748 LCATLAHYAHLC-RRHGLPVDFR----ARLPACALSCEASKEYSPCVAPCGRTCQDLASP 802

Query: 324 SLC---------EEHRMDGCFCPEGAQAD 343
             C          +  ++GC CP     D
Sbjct: 803 EACGVDGGDDLSRDECVEGCACPPDTYLD 831



 Score = 96.7 bits (239), Expect = 3e-19
 Identities = 152/720 (21%), Positives = 241/720 (33%), Gaps = 105/720 (14%)

Query: 1031 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1090
            CEW Y+ C +  F+TCR      S   V     C P CP  + + +E  ++CV  + C  
Sbjct: 1408 CEWRYDACASPCFQTCRDPRAA-SCRDVPRGRSCVPVCPTPQ-VLDEVTQRCVYLEDC-- 1463

Query: 1091 YVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1150
                    P   VPTE      +  +        EE + L+Q       +     P   +
Sbjct: 1464 ------VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQ-LSQESPRTPTHRPALTPAAPL 1516

Query: 1151 EKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSS----------TVLSTTP 1200
                N     T    ++   T T    P   T +     PT S            +  TP
Sbjct: 1517 TTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1576

Query: 1201 KLCCLWSDWINEDHPSSGSDDGDRETFDGV---CGAPE-DIECRSVKDPHLSLEQLGQKV 1256
            +   L    +    P+ G   G  ET        G+P   +  RS   P           
Sbjct: 1577 ESSSL---PVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFP-------- 1625

Query: 1257 QLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPI 1316
                     L+ K    +  G +P+                 + T    + T +P+  P+
Sbjct: 1626 ---------LMTKAVTVRGHGSLPV-----------------RTTPPQPSLTASPSSRPV 1659

Query: 1317 TTTTTVTPTPTPTSTQSTTPTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1373
             +   ++ +PT + +     TP  T   + T  P PT   + +  +TP+T   T      
Sbjct: 1660 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGT------ 1713

Query: 1374 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTT-TPIT 1432
                Q P  +P+ T +      T  G +   S P+ +  +  P P P+    P   T + 
Sbjct: 1714 -AAEQVP-VSPLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMA 1770

Query: 1433 TTTTVTPTPTP------TGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPT 1486
            T +   P  TP      T T     T   +  +  P+   +G    T+ P+    T  P 
Sbjct: 1771 TRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAP- 1829

Query: 1487 PTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPI 1546
                   TP P A   TT + P          T+ P  T + V P      TQ   PT I
Sbjct: 1830 -----VATPGPKASVITTPLQP--------QATTLPAQTLSPVLPFTPAAMTQAHPPTHI 1876

Query: 1547 STTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP 1604
            +     T      G   PT+   P+   T    +  P  + T    +++   ++ PT   
Sbjct: 1877 APPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSL-PTSMY 1935

Query: 1605 TSTKS--TTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTS 1662
             S +   T +TP T+         P G Q  T +P+ T+  ++     T           
Sbjct: 1936 GSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDS--MLVL 1993

Query: 1663 TAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST---LPPAIEMTSTAPPSTPTAP 1719
               +AE   ++  P  +      +T+ P   S   LS    L  A+  T+ A  ST   P
Sbjct: 1994 LPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 78/317 (24%), Positives = 124/317 (39%), Gaps = 18/317 (5%)

Query: 35  NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
           ++C  WG  H +TFDG  +   G   Y          + F++ +   P    +P      
Sbjct: 149 SICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRA 208

Query: 95  --LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152
             L  + +  I+L + +    G  V  PH      +++   Y  V  ++  TL W+   A
Sbjct: 209 VSLFFVGEQEIHLAKEVTH-GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASA 267

Query: 153 LMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNM---QKINQP-----D 203
           + +++  +    T GLCG+ N         S G L   + EF +    Q  NQP      
Sbjct: 268 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327

Query: 204 VVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
            +   P  +  P +      +CE LL    F  C   V   P+  +C  D C+  G    
Sbjct: 328 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 386

Query: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323
            C  +AE++R C+ AG     WRT     +    +       Y E  + C  +C H   S
Sbjct: 387 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKA---FTYNECIACCPASC-HPRAS 442

Query: 324 SLCEEHR-MDGCFCPEG 339
            +  E   +DGC+CP G
Sbjct: 443 CVDSEIACVDGCYCPNG 459



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 70/313 (22%), Positives = 118/313 (37%), Gaps = 46/313 (14%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C    C   CT +GD HY TFDGL + + G C   LV+  S S  +F V ++N +C  + 
Sbjct: 976  CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK--STSDVSFSVIVENVNCYSSG 1033

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
             + C + + +      ++       P       ++Q V           ++ G   +V  
Sbjct: 1034 MI-CRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEV---------HTWRVGFFTLVHF 1083

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 2111
            P+  + + ++  +        ++     G CG     T ++   P    ++N +     W
Sbjct: 1084 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1143

Query: 2112 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL--------CQLIKDSLFAQ 2163
               +     CP +                  P   C  +PL        C ++   +F  
Sbjct: 1144 AAVE-----CPDTLD----------------PRDMCVLNPLREPFAKKECSILLSEVFEI 1182

Query: 2164 CHALVPPQHYYDACVFDSC-FMPGSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLV 2220
            CH +V    +Y  C+ D+C    G   EC  AS+ AYA  C Q  + +DWR  T   C  
Sbjct: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLCPY 1240

Query: 2221 ECPSHREYQACGP 2233
            +C    +    GP
Sbjct: 1241 DCDFFNKVLGKGP 1253



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 89/398 (22%), Positives = 145/398 (36%), Gaps = 67/398 (16%)

Query: 752  CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY----------CGQNSSLGS- 800
            C    C   CSI+    ++TFDG +        Y+  Q            C ++++LG  
Sbjct: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHL 2160

Query: 801  ----FSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVG 856
                F ++  N+    T +     I  F  +  + L+     V +        +   + G
Sbjct: 2161 NWPPFCLVMLNM----THLAHQVTIDRFNRKVTVDLQPVWPPVSR------YGFRIEDTG 2210

Query: 857  QYLVVESSTGIIVIW-DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSE 915
               ++ + + I + W      + ++ + + K    GLCG  D  + ND T +D  VV   
Sbjct: 2211 HMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGA 2270

Query: 916  LD---FGNSWKEAPTCPDVSTN---PEPCSLNPHRRSWAEKQCS----ILKSSVFSICHS 965
             D   F +SW+   +   V      P+ C         A   CS    ++ +  FS CH 
Sbjct: 2271 EDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHR 2321

Query: 966  KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYY 1025
             V P+ F E  + D+            C A+  Y   C K   C+ WR  D CP  C   
Sbjct: 2322 FVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2375

Query: 1026 NPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYL----EGCYPRCPKDRPIYEEDLKK 1081
            +    C    EP      +TC+  +GI   +   +     EGC   C +   ++      
Sbjct: 2376 STYQACVTACEPP-----KTCQ--DGILGPLDPEHCQVLGEGCV--CSEGTILHRRHSAL 2426

Query: 1082 CVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQ 1119
            C+   KC C   D+   P A   T  +  S  C +  Q
Sbjct: 2427 CIPEAKCAC--TDSMGVPRALGETWNSSLSGCCQHQCQ 2462



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 66/274 (24%), Positives = 120/274 (43%), Gaps = 43/274 (15%)

Query: 35   NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
            + C+ +G+ HY+TFDG  F F G C                VHL +          VE++
Sbjct: 983  STCTAYGDRHYRTFDGLPFDFVGACK---------------VHLVKSTSDVSFSVIVENV 1027

Query: 95   ------LLTIKDDTIYLTRHLAVLNGAVVSTPHYSP-GLLIEKSDAYT--------KVYS 139
                  ++  K  +I +   L V +     + + SP   L +K + +T          + 
Sbjct: 1028 NCYSSGMICRKFISINVGNSLIVFDD---DSGNPSPESFLDDKQEVHTWRVGFFTLVHFP 1084

Query: 140  RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDG--VLFSPLEFGNM- 196
            +  +TL+W++   + ++   +++    GLCG+++ L++ +E  +     L +P EFG+  
Sbjct: 1085 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFD-LKTINEMRTPENLELTNPQEFGSSW 1143

Query: 197  QKINQPDVVCEDPEEEVAPASCSEHRAECE-RLLTAEAFADCQDLVPLEPYLRACQQDRC 255
              +  PD +  DP +        E  A+ E  +L +E F  C  +V +  +   C  D C
Sbjct: 1144 AAVECPDTL--DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTC 1201

Query: 256  RCPGGD--TCVCSTVAEFSRQCSHAGGRPGNWRT 287
             C  G    C C++V+ ++ QC   G    +WRT
Sbjct: 1202 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRT 1234



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 59/226 (26%), Positives = 84/226 (37%), Gaps = 39/226 (17%)

Query: 413  LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATG---AGFANTWKAQSSCHD--K 467
            + V   + S+ Q  GLCG  +G   +D     G V       A F ++W+  SS     +
Sbjct: 2232 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2291

Query: 468  LDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNED 527
              +  D C+    S       C  +    T F  CH  V P  + +    DT   Q    
Sbjct: 2292 TRFRPDSCATTDCSP------CLRMVSNRT-FSACHRFVPPESFCELWIRDTKYVQQP-- 2342

Query: 528  CLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADS 587
              C AL+ Y   C    V +  WR          CP    FL +  +  Q C +  E   
Sbjct: 2343 --CVALTVYVAMCHKFHVCI-EWRRS------DYCP----FLCSSDSTYQACVTACEPPK 2389

Query: 588  HCLEGF-APVD---------GCGCPDHTFLDEK--GRCVPLAKCSC 621
             C +G   P+D         GC C + T L  +    C+P AKC+C
Sbjct: 2390 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435


>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score =  430 bits (1105), Expect = e-119
 Identities = 243/698 (34%), Positives = 377/698 (54%), Gaps = 39/698 (5%)

Query: 347  TVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQ 406
            +V+L  D ++ V + ++   +L ++ ++  P+   +F + R SS  + V   +GVR+   
Sbjct: 498  SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYD 557

Query: 407  LAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHD 466
                ++L++ +DQ       GLCG FNG   DDF +  G+ E+T   F N+WK  S+C  
Sbjct: 558  REG-LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP 616

Query: 467  KLDWLD-DPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNN 525
             +     DPC +++++A+Y+   CS+L  T   F  C + + P  Y+++C+ D C C   
Sbjct: 617  LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC--G 672

Query: 526  EDCLCAALSSYARACTAKGVML-WGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE 584
            + CLCA L+ YA  C   G+ + +  R   C     SC  S+ +   +  C +TC+ L+ 
Sbjct: 673  QPCLCATLAHYAHLCRRHGLPVDFRARLPACAL---SCEASKEYSPCVAPCGRTCQDLAS 729

Query: 585  ADSHCLEGFAP------VDGCGCPDHTFLDEKGR-CVPLAKCSCYHRGLYLEAGDVVVRQ 637
             ++  ++G         V+GC CP  T+LD +   CVP  +CSC+ +G+    GD  +  
Sbjct: 730  PEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 789

Query: 638  EERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNL-TALATSKPRALSCQTLAAGYY-HT 695
               C C+DG + C   R    +C A ++ ++CS+L T L  S+ R    Q L        
Sbjct: 790  LGHCHCKDGVMSCDS-RAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 848

Query: 696  ECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQA 755
             C+SGC CP GL+  G   C + +ECPC      Y  G ++   C+TC C+RG + CT  
Sbjct: 849  PCLSGCACPQGLLRHG-DACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 907

Query: 756  VCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGV 815
             C  TC+ YG  HY TFDG  +DF G C    V+     ++S  SFS+I ENV C ++G+
Sbjct: 908  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVSFSVIVENVNCYSSGM 962

Query: 816  TCSKAIKIFMGRTELKLEDK------HRVVIQRDEGHHVAYTTREVGQYLVVE-SSTGII 868
             C K I I +G + +  +D          +  + E H     T  VG + +V      I 
Sbjct: 963  ICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVH-----TWRVGFFTLVHFPQEHIT 1017

Query: 869  VIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC 928
            ++WD+RTTV ++  P ++G + GLCGNFD ++ N+  T +++ +++  +FG+SW  A  C
Sbjct: 1018 LLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA-AVEC 1076

Query: 929  PDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGD 988
            PD     + C LNP R  +A+K+CSIL S VF ICH  VD   FY  C+ D+C C  GGD
Sbjct: 1077 PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGD 1136

Query: 989  CECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1026
            CECFC++V++YA +C + G  V WRTP LCP  CD++N
Sbjct: 1137 CECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174



 Score =  237 bits (605), Expect = 1e-61
 Identities = 319/1356 (23%), Positives = 478/1356 (35%), Gaps = 232/1356 (17%)

Query: 1288 EINVQCC---ECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTT 1344
            E+  +C    +CV     + T    N T  P    +   PTP+    Q +  +P   T T
Sbjct: 1380 EVTQRCVYLEDCVEPAVWVPTEALGNETLPP----SQGLPTPSDEEPQLSQESP--RTPT 1433

Query: 1345 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1404
              P  TP    T    P   T T  P  +P  TQT    P+  T +  P      T++P 
Sbjct: 1434 HRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPLELTASQLPAGP---TESPA 1489

Query: 1405 STPITTTTTVTP-TPT----PTGTQTPT---------TTPITTTTTVTPTPTPTGTQAPT 1450
            S  +T +    P TP     P   QTPT         TT +T     +P  T +    P 
Sbjct: 1490 SKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPA 1549

Query: 1451 PTAITTTSTVT----------PTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQ----TP 1495
            P     T  VT           TP  P+ T +P++ P+ +   ++ +PT +G+     TP
Sbjct: 1550 PRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTP 1609

Query: 1496 TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPT 1555
              T + + T V P PT   + +  STP+T   T          Q P  +P++T +     
Sbjct: 1610 AVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAE-------QVPV-SPLATRSLEIVL 1660

Query: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-VLITTTTTMTPTPTP------TSTK 1608
             T  G +   + P+ +  +  P P P+    P     + T +   P  TP      T+T 
Sbjct: 1661 STEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATD 1719

Query: 1609 STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAE 1668
                TP  +  +   +   +G    T +P++   T  P  TP     GP     T P+  
Sbjct: 1720 GLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP-----GPKASVITTPLQP 1774

Query: 1669 LTTSNP-------------------PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
              T+ P                   PP    P  + +    L  +T   S + P  E T+
Sbjct: 1775 QATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTA 1834

Query: 1710 TAPPSTPTAPTTTSGG---HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 1766
            +     P   TT         +S P S   S  G PT   T  +S   TP   +     A
Sbjct: 1835 SMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE-LTPATSHPLTPLVAEPEGAQA 1893

Query: 1767 WTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLS 1826
             T  P P S      +    P  S +++   L + +         GT             
Sbjct: 1894 GTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAH---------GTSAGPHLAAEPVDE 1944

Query: 1827 CTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWW 1886
             T E    S P+             T    +ST   P                       
Sbjct: 1945 ATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------------------- 1985

Query: 1887 LCDCFMATCKYNNTVEIVKVECEPPPM--PTCSNGLQPVRVEDPDGCCWHWECDCYCTGW 1944
              DC    C     + + + +  P     P C      VRV   D CC  WEC C C+ +
Sbjct: 1986 --DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIF 2042

Query: 1945 GDPHYVTFDGLYYSYQGNCTYVLVEEISPS-------VDNFGVYIDNYHCDPNDKVSCPR 1997
             D  +VTFDG + +      Y+L +  SP        +D     + + +  P     C  
Sbjct: 2043 PDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLDCKSANLGHLNWPP----FCLV 2096

Query: 1998 TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVL 2057
             L + H   +V I   +      +V V+ Q V  P  +YG  +  +G  Y++  P    +
Sbjct: 2097 MLNMTHLAHQVTIDRFNR-----KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQI 2151

Query: 2058 VSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA---DQWLVN 2114
               +     +            G CG C    ++D  L  G +V   E  A   D W V 
Sbjct: 2152 QWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVP 2211

Query: 2115 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYY 2174
                     SS T+       P    TT   DC  SP  +++ +  F+ CH  VPP+ + 
Sbjct: 2212 ---------SSLTSVGQTRFRPDSCATT---DC--SPCLRMVSNRTFSACHRFVPPESFC 2257

Query: 2175 DACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPA 2234
            +  + D+ ++      C +L  Y A+C + ++C++WR   +  C   C S   YQAC  A
Sbjct: 2258 ELWIRDTKYV---QQPCVALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTA 2312

Query: 2235 EEP--TCKSSS----SQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPRE 2286
             EP  TC+         ++  VL EGC C EGT+ +     +C+    C C     VPR 
Sbjct: 2313 CEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2372

Query: 2287 FGEHFEFDCKNCVC--LEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITV 2344
             GE +      C     +    I+     C       C+  G  +A  +   D CC  TV
Sbjct: 2373 LGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE-VALLLPTKDPCCLGTV 2431

Query: 2345 CKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCE-SKGVCVHGNAEYQPG------- 2396
            C CN +LC+     C  G  + +      CCP Y CE    +C    AE  P        
Sbjct: 2432 CVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLC---EAELVPSCRQDQIL 2488

Query: 2397 ---------SPVYSSKCQDC-----VCTD----KVDNNTL-----LNVIACTHVPC-NTS 2432
                        Y   C DC      C +     V  NT      L    C +  C    
Sbjct: 2489 ITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQ 2548

Query: 2433 CSPGFELME--APGECC--KKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKI 2488
            C  G  L+E  +P  CC  K CE   C               D  + P   C  +   ++
Sbjct: 2549 CGLGTALVEVWSPDRCCPYKSCE---C---------------DCDTIPVPRCHLWEKSQL 2590

Query: 2489 HNQLISSVSNIT-CPNFD---ASICIPGSITFMPNG 2520
              + + SV N+  C  ++   A +C+   +  M  G
Sbjct: 2591 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPG 2626



 Score =  231 bits (589), Expect = 7e-60
 Identities = 190/769 (24%), Positives = 312/769 (40%), Gaps = 164/769 (21%)

Query: 372  LQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGN 431
            ++V LPHV  S  + + + Y I+   +      +       +++ +     G   GLCGN
Sbjct: 158  MRVQLPHVMGSARLQQLAGYVIVRHQSA---FTLAWDGASAVYIKMSPELLGWTHGLCGN 214

Query: 432  FNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDD----PC-SLNIESANYAE 486
             N    DD  T+SG +      F ++W+ Q+               PC   N  +     
Sbjct: 215  NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274

Query: 487  HWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVM 546
              C  L +   PF  CH+ V P  +       T +C ++   LC ++           V 
Sbjct: 275  EQCEALLRP--PFDACHAYVSPLPF-------TASCTSD---LCQSMGD---------VA 313

Query: 547  LWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTF 606
             W                              CR+L+E    C +   P+ G        
Sbjct: 314  TW------------------------------CRALAEYARACAQAGRPLQGW------- 336

Query: 607  LDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIH 666
                                             R   R   +HC++       C A    
Sbjct: 337  ---------------------------------RTQLRQCTVHCKEKAFTYNECIA---- 359

Query: 667  MDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHN 726
                     A+  PRA    +  A      CV GC CP+GL+ +  GGCV   ECPC  +
Sbjct: 360  ------CCPASCHPRASCVDSEIA------CVDGCYCPNGLIFED-GGCVAPAECPCEFH 406

Query: 727  NDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYV 786
              LY  G+ +K DCNTCTC  G+W C+ AVC   CS+ G  H+ TFDG+ Y F   C Y+
Sbjct: 407  GTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYI 466

Query: 787  AVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRT-----------ELKLED 834
                   ++ S G+F++  +N PCG      C +++ + + +            ++ L D
Sbjct: 467  -----LAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFD 521

Query: 835  KHRVVIQRDEGHHVAYTTREVGQ-YLVVESSTGIIVIWDKR-TTVFIKLAPSYKGTVCGL 892
            +++++    +    A+  R +   +L V ++ G+ V++D+    +++++   +     GL
Sbjct: 522  QYKIIPPYTDD---AFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGL 578

Query: 893  CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC-PDVSTNP-EPCSLNPHRRSWAEK 950
            CG F+  + +DF +   +  S+   FGNSWK    C P VS +P +PC ++    S++ +
Sbjct: 579  CGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQ 638

Query: 951  QCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV 1010
             CS+L   +F+ C + + P P++E C  D+C C       C C+ +A YA  C + G  V
Sbjct: 639  ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPV 694

Query: 1011 FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTIN-----GIHSNISVS---YL 1061
             +R     C + C       E    Y PC      TC+ +      G+     +S    +
Sbjct: 695  DFRARLPACALSC-------EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 747

Query: 1062 EGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGAS-VPTEETC 1109
            EGC   CP D  + +     CV  ++C C+ +   YPPG S +P+   C
Sbjct: 748  EGC--ACPPDTYL-DTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 793



 Score =  157 bits (398), Expect = 1e-37
 Identities = 125/396 (31%), Positives = 180/396 (45%), Gaps = 40/396 (10%)

Query: 761  CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG-SFSIITENVP-CGTTGVTCS 818
            C  +G  H  TFDG YY   G  SY  V    G++   G SFSI   N P CG++  TCS
Sbjct: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 134

Query: 819  KAIKIF-MGRTELKLEDKHRVVIQRDEGHHVAYTTR--EVGQYLVVESSTGIIVIWDKRT 875
            +A+ +F +G  E+ L  +      R +  HV  + R  ++  Y++V   +   + WD  +
Sbjct: 135  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 194

Query: 876  TVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE----APTCPDV 931
             V+IK++P   G   GLCGN +    +D  T    +    ++F +SW+E     P  P  
Sbjct: 195  AVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTT 254

Query: 932  STNPEPCSL--NPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC 989
            S+ P P  L  NP       +QC  L    F  CH+ V P PF  +C  D   C + GD 
Sbjct: 255  SSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LCQSMGDV 312

Query: 990  ECFCSAVASYAQECTKEGACV-FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1047
              +C A+A YA+ C + G  +  WRT    C + C       E  + Y  C      +C 
Sbjct: 313  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC------KEKAFTYNECIACCPASCH 366

Query: 1048 TINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEE 1107
                   +  ++ ++GCY  CP    I+E+    CV   +C C    T YPPG+ V  +E
Sbjct: 367  P-RASCVDSEIACVDGCY--CPNGL-IFEDG--GCVAPAECPCEFHGTLYPPGSVV--KE 418

Query: 1108 TCKSCVCTNS----SQVVCRPE---EGKILNQTQDG 1136
             C +C CT+     S  VC  E    G I   T DG
Sbjct: 419  DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 454



 Score =  119 bits (297), Expect = 5e-26
 Identities = 139/580 (23%), Positives = 226/580 (38%), Gaps = 108/580 (18%)

Query: 1895 CKYNNTV----EIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECD-----CYCTGWG 1945
            C+++ T+     +VK +C      TC++G               WEC        C+  G
Sbjct: 403  CEFHGTLYPPGSVVKEDCNTC---TCTSG--------------KWECSTAVCPAECSVTG 445

Query: 1946 DPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTL-IVRHE 2004
            D H+ TFDG  Y++   C Y+L +  S S   F V + N  C  N   +C +++ ++ H+
Sbjct: 446  DIHFTTFDGRRYTFPATCQYILAK--SRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 503

Query: 2005 TQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN--G 2062
                  + V +      +  ++  +  PY     E+ +    ++     +GV V Y+  G
Sbjct: 504  DPR---RQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560

Query: 2063 LSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCP 2122
            L   +++   R+  +T G CGT    T DD + P G   S  +   + W       P   
Sbjct: 561  LRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV- 618

Query: 2123 HSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC 2182
             S S      V +     +           C ++   +FA C A + P  Y++ C  D+C
Sbjct: 619  -SGSPLDPCDVHLQAASYSV--------QACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669

Query: 2183 FMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 2242
               G    CA+L  YA LC +  + +D+R     AC + C + +EY  C      TC+  
Sbjct: 670  -RCGQPCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPCGRTCQDL 727

Query: 2243 SSQQ----------NNTVLVEGCFCPEGTMNYAPGFDVCV--KTCGC--VGPDNVPREFG 2288
            +S +          +    VEGC CP  T       D+CV    C C   G D  P   G
Sbjct: 728  ASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-DLCVPRNQCSCHFQGVDYPP---G 783

Query: 2289 EHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCN 2348
            +       +C C +G   + C     S+ P   C     +    VN +D   ++ + +  
Sbjct: 784  DSDIPSLGHCHCKDG--VMSCD----SRAPAAACPAGQVF----VNCSDLHTDLELSRER 833

Query: 2349 TSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA--------------EYQ 2394
            T  C+++  +  L    +   + G  CP      +G+  HG+A              EY 
Sbjct: 834  T--CEQQ--LLNLSVSARGPCLSGCACP------QGLLRHGDACFLPEECPCTWKGKEYF 883

Query: 2395 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434
            PG  V  S C  CVC              CT  PC ++C+
Sbjct: 884  PGDQV-MSPCHTCVCQ--------RGSFQCTLHPCASTCT 914



 Score =  115 bits (289), Expect = 4e-25
 Identities = 109/399 (27%), Positives = 155/399 (38%), Gaps = 49/399 (12%)

Query: 1936 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 1995
            E D  C  WG  H  TFDGLYY   G  +Y LV    P   +F + + N     +   +C
Sbjct: 74   ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 133

Query: 1996 PR--TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE 2053
             R  +L    E +  L K V    M+VQ         LP+   G    Q    YV+   +
Sbjct: 134  SRAVSLFFVGEQEIHLAKEVTHGGMRVQ---------LPH-VMGSARLQQLAGYVIVRHQ 183

Query: 2054 LGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV 2113
                ++++G S             T G CG       DD +  SG++  +       W  
Sbjct: 184  SAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE 243

Query: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHY 2173
              P++P  P +SS  + P +    G     ++       C+ +    F  CHA V P  +
Sbjct: 244  QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRPPFDACHAYVSPLPF 297

Query: 2174 YDACVFDSCFMPGS-SLECASLQAYAALCAQQNICLD-WRNHTHGACLVECP----SHRE 2227
              +C  D C   G  +  C +L  YA  CAQ    L  WR      C V C     ++ E
Sbjct: 298  TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNE 356

Query: 2228 YQACGPAEEPTCKSSSSQQNNTV-LVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 2286
              AC PA   +C   +S  ++ +  V+GC+CP G         +  +  GCV P   P E
Sbjct: 357  CIACCPA---SCHPRASCVDSEIACVDGCYCPNG---------LIFEDGGCVAPAECPCE 404

Query: 2287 F-------GEHFEFDCKNCVCLEGG---SGIICQPKRCS 2315
            F       G   + DC  C C  G    S  +C P  CS
Sbjct: 405  FHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC-PAECS 442



 Score =  109 bits (273), Expect = 3e-23
 Identities = 91/329 (27%), Positives = 145/329 (44%), Gaps = 32/329 (9%)

Query: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGP-GQAEAPAGVESIL 95
           CS  G+ H+ TFDG  + FP  C Y  A     S   F V L+  P G  +  A V+S+ 
Sbjct: 441 CSVTGDIHFTTFDGRRYTFPATCQYILAKS--RSSGTFTVTLQNAPCGLNQDGACVQSVS 498

Query: 96  LTIKDD-----TIYLTRHLAVLNGAVVSTPHYSPGLLIEK-SDAYTKVYSRAGLTLMWNR 149
           + +  D     T+     + + +   +  P+      I + S  + +V +  G+ ++++R
Sbjct: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558

Query: 150 ED-ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSD-GVLFS-PLEFGNMQKINQ--PDV 204
           E   L L++D ++   T GLCG +NG  +  +FLS  GV  S P  FGN  K       +
Sbjct: 559 EGLRLYLQVDQRWVEDTVGLCGTFNG-NTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 617

Query: 205 VCEDPEEEV-APASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
           V   P +        + +  +   +LT E FA C   +   PY   C++D CRC  G  C
Sbjct: 618 VSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRC--GQPC 675

Query: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323
           +C+T+A ++  C    G P ++R    A  P  + +C  +  Y    +PC  TC  L   
Sbjct: 676 LCATLAHYAHLC-RRHGLPVDFR----ARLPACALSCEASKEYSPCVAPCGRTCQDLASP 730

Query: 324 SLC---------EEHRMDGCFCPEGAQAD 343
             C          +  ++GC CP     D
Sbjct: 731 EACGVDGGDDLSRDECVEGCACPPDTYLD 759



 Score =  104 bits (259), Expect = 1e-21
 Identities = 154/720 (21%), Positives = 245/720 (34%), Gaps = 105/720 (14%)

Query: 1031 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1090
            CEW Y+ C +  F+TCR      S   V  +EGC P CP  + + +E  ++CV  + C  
Sbjct: 1336 CEWRYDACASPCFQTCRDPRAA-SCRDVPRVEGCVPVCPTPQ-VLDEVTQRCVYLEDC-- 1391

Query: 1091 YVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1150
                    P   VPTE      +  +        EE + L+Q       +     P   +
Sbjct: 1392 ------VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQ-LSQESPRTPTHRPALTPAAPL 1444

Query: 1151 EKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSS----------TVLSTTP 1200
                N     T    ++   T T    P   T +     PT S            +  TP
Sbjct: 1445 TTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1504

Query: 1201 KLCCLWSDWINEDHPSSGSDDGDRETFDGV---CGAPE-DIECRSVKDPHLSLEQLGQKV 1256
            +   L    +    P+ G   G  ET        G+P   +  RS   P           
Sbjct: 1505 ESSSL---PVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFP-------- 1553

Query: 1257 QLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPI 1316
                     L+ K    +  G +P+                 + T +  + T +P+  P+
Sbjct: 1554 ---------LMTKAVTVRGHGSLPV-----------------RTTPLQPSLTASPSSRPV 1587

Query: 1317 TTTTTVTPTPTPTSTQSTTPTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1373
             +   ++ +PT + +     TP  T   + T  P PT   + +  +TP+T   T      
Sbjct: 1588 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGT------ 1641

Query: 1374 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTT-TPIT 1432
                Q P  +P+ T +      T  G +   S P+ +  +  P P P+    P   T + 
Sbjct: 1642 -AAEQVP-VSPLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMA 1698

Query: 1433 TTTTVTPTPTP------TGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPT 1486
            T +   P  TP      T T     T   +  +  P+   +G    T+ P+    T  P 
Sbjct: 1699 TRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAP- 1757

Query: 1487 PTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPI 1546
                   TP P A   TT + P          T+ P  T + V P      TQ   PT I
Sbjct: 1758 -----VATPGPKASVITTPLQP--------QATTLPAQTLSPVLPFTPAAMTQAHPPTHI 1804

Query: 1547 STTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP 1604
            +     T      G   PT+   P+   T    +  P  + T    +++   ++ PT   
Sbjct: 1805 APPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSL-PTSMY 1863

Query: 1605 TSTKS--TTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTS 1662
             S +   T +TP T+         P G Q  T +P+ T+  ++     T           
Sbjct: 1864 GSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDS--MLVL 1921

Query: 1663 TAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST---LPPAIEMTSTAPPSTPTAP 1719
               +AE   ++  P  +      +T+ P   S   LS    L  A+  T+ A  ST   P
Sbjct: 1922 LPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 78/317 (24%), Positives = 124/317 (39%), Gaps = 18/317 (5%)

Query: 35  NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
           ++C  WG  H +TFDG  +   G   Y          + F++ +   P    +P      
Sbjct: 77  SICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRA 136

Query: 95  --LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152
             L  + +  I+L + +    G  V  PH      +++   Y  V  ++  TL W+   A
Sbjct: 137 VSLFFVGEQEIHLAKEVTH-GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASA 195

Query: 153 LMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNM---QKINQP-----D 203
           + +++  +    T GLCG+ N         S G L   + EF +    Q  NQP      
Sbjct: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255

Query: 204 VVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
            +   P  +  P +      +CE LL    F  C   V   P+  +C  D C+  G    
Sbjct: 256 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 314

Query: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323
            C  +AE++R C+ AG     WRT     +    +       Y E  + C  +C H   S
Sbjct: 315 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKA---FTYNECIACCPASC-HPRAS 370

Query: 324 SLCEEHR-MDGCFCPEG 339
            +  E   +DGC+CP G
Sbjct: 371 CVDSEIACVDGCYCPNG 387



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 70/313 (22%), Positives = 118/313 (37%), Gaps = 46/313 (14%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C    C   CT +GD HY TFDGL + + G C   LV+  S S  +F V ++N +C  + 
Sbjct: 904  CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK--STSDVSFSVIVENVNCYSSG 961

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
             + C + + +      ++       P       ++Q V           ++ G   +V  
Sbjct: 962  MI-CRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEV---------HTWRVGFFTLVHF 1011

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 2111
            P+  + + ++  +        ++     G CG     T ++   P    ++N +     W
Sbjct: 1012 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1071

Query: 2112 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL--------CQLIKDSLFAQ 2163
               +     CP +                  P   C  +PL        C ++   +F  
Sbjct: 1072 AAVE-----CPDTLD----------------PRDMCVLNPLREPFAKKECSILLSEVFEI 1110

Query: 2164 CHALVPPQHYYDACVFDSC-FMPGSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLV 2220
            CH +V    +Y  C+ D+C    G   EC  AS+ AYA  C Q  + +DWR  T   C  
Sbjct: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLCPY 1168

Query: 2221 ECPSHREYQACGP 2233
            +C    +    GP
Sbjct: 1169 DCDFFNKVLGKGP 1181



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 89/398 (22%), Positives = 145/398 (36%), Gaps = 67/398 (16%)

Query: 752  CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY----------CGQNSSLGS- 800
            C    C   CSI+    ++TFDG +        Y+  Q            C ++++LG  
Sbjct: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHL 2088

Query: 801  ----FSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVG 856
                F ++  N+    T +     I  F  +  + L+     V +        +   + G
Sbjct: 2089 NWPPFCLVMLNM----THLAHQVTIDRFNRKVTVDLQPVWPPVSR------YGFRIEDTG 2138

Query: 857  QYLVVESSTGIIVIW-DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSE 915
               ++ + + I + W      + ++ + + K    GLCG  D  + ND T +D  VV   
Sbjct: 2139 HMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGA 2198

Query: 916  LD---FGNSWKEAPTCPDVSTN---PEPCSLNPHRRSWAEKQCS----ILKSSVFSICHS 965
             D   F +SW+   +   V      P+ C         A   CS    ++ +  FS CH 
Sbjct: 2199 EDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHR 2249

Query: 966  KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYY 1025
             V P+ F E  + D+            C A+  Y   C K   C+ WR  D CP  C   
Sbjct: 2250 FVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2303

Query: 1026 NPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYL----EGCYPRCPKDRPIYEEDLKK 1081
            +    C    EP      +TC+  +GI   +   +     EGC   C +   ++      
Sbjct: 2304 STYQACVTACEPP-----KTCQ--DGILGPLDPEHCQVLGEGCV--CSEGTILHRRHSAL 2354

Query: 1082 CVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQ 1119
            C+   KC C   D+   P A   T  +  S  C +  Q
Sbjct: 2355 CIPEAKCAC--TDSMGVPRALGETWNSSLSGCCQHQCQ 2390



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 66/274 (24%), Positives = 120/274 (43%), Gaps = 43/274 (15%)

Query: 35   NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
            + C+ +G+ HY+TFDG  F F G C                VHL +          VE++
Sbjct: 911  STCTAYGDRHYRTFDGLPFDFVGACK---------------VHLVKSTSDVSFSVIVENV 955

Query: 95   ------LLTIKDDTIYLTRHLAVLNGAVVSTPHYSP-GLLIEKSDAYT--------KVYS 139
                  ++  K  +I +   L V +     + + SP   L +K + +T          + 
Sbjct: 956  NCYSSGMICRKFISINVGNSLIVFDD---DSGNPSPESFLDDKQEVHTWRVGFFTLVHFP 1012

Query: 140  RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDG--VLFSPLEFGNM- 196
            +  +TL+W++   + ++   +++    GLCG+++ L++ +E  +     L +P EFG+  
Sbjct: 1013 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFD-LKTINEMRTPENLELTNPQEFGSSW 1071

Query: 197  QKINQPDVVCEDPEEEVAPASCSEHRAECE-RLLTAEAFADCQDLVPLEPYLRACQQDRC 255
              +  PD +  DP +        E  A+ E  +L +E F  C  +V +  +   C  D C
Sbjct: 1072 AAVECPDTL--DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTC 1129

Query: 256  RCPGGD--TCVCSTVAEFSRQCSHAGGRPGNWRT 287
             C  G    C C++V+ ++ QC   G    +WRT
Sbjct: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRT 1162



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 59/226 (26%), Positives = 84/226 (37%), Gaps = 39/226 (17%)

Query: 413  LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATG---AGFANTWKAQSSCHD--K 467
            + V   + S+ Q  GLCG  +G   +D     G V       A F ++W+  SS     +
Sbjct: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219

Query: 468  LDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNED 527
              +  D C+    S       C  +    T F  CH  V P  + +    DT   Q    
Sbjct: 2220 TRFRPDSCATTDCSP------CLRMVSNRT-FSACHRFVPPESFCELWIRDTKYVQQP-- 2270

Query: 528  CLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADS 587
              C AL+ Y   C    V +  WR          CP    FL +  +  Q C +  E   
Sbjct: 2271 --CVALTVYVAMCHKFHVCI-EWRRS------DYCP----FLCSSDSTYQACVTACEPPK 2317

Query: 588  HCLEGF-APVD---------GCGCPDHTFLDEK--GRCVPLAKCSC 621
             C +G   P+D         GC C + T L  +    C+P AKC+C
Sbjct: 2318 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363


>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score =  430 bits (1105), Expect = e-119
 Identities = 243/698 (34%), Positives = 377/698 (54%), Gaps = 39/698 (5%)

Query: 347  TVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQ 406
            +V+L  D ++ V + ++   +L ++ ++  P+   +F + R SS  + V   +GVR+   
Sbjct: 570  SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYD 629

Query: 407  LAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHD 466
                ++L++ +DQ       GLCG FNG   DDF +  G+ E+T   F N+WK  S+C  
Sbjct: 630  REG-LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP 688

Query: 467  KLDWLD-DPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNN 525
             +     DPC +++++A+Y+   CS+L  T   F  C + + P  Y+++C+ D C C   
Sbjct: 689  LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC--G 744

Query: 526  EDCLCAALSSYARACTAKGVML-WGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE 584
            + CLCA L+ YA  C   G+ + +  R   C     SC  S+ +   +  C +TC+ L+ 
Sbjct: 745  QPCLCATLAHYAHLCRRHGLPVDFRARLPACAL---SCEASKEYSPCVAPCGRTCQDLAS 801

Query: 585  ADSHCLEGFAP------VDGCGCPDHTFLDEKGR-CVPLAKCSCYHRGLYLEAGDVVVRQ 637
             ++  ++G         V+GC CP  T+LD +   CVP  +CSC+ +G+    GD  +  
Sbjct: 802  PEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 861

Query: 638  EERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNL-TALATSKPRALSCQTLAAGYY-HT 695
               C C+DG + C   R    +C A ++ ++CS+L T L  S+ R    Q L        
Sbjct: 862  LGHCHCKDGVMSCDS-RAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 920

Query: 696  ECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQA 755
             C+SGC CP GL+  G   C + +ECPC      Y  G ++   C+TC C+RG + CT  
Sbjct: 921  PCLSGCACPQGLLRHG-DACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 979

Query: 756  VCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGV 815
             C  TC+ YG  HY TFDG  +DF G C    V+     ++S  SFS+I ENV C ++G+
Sbjct: 980  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVSFSVIVENVNCYSSGM 1034

Query: 816  TCSKAIKIFMGRTELKLEDK------HRVVIQRDEGHHVAYTTREVGQYLVVE-SSTGII 868
             C K I I +G + +  +D          +  + E H     T  VG + +V      I 
Sbjct: 1035 ICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVH-----TWRVGFFTLVHFPQEHIT 1089

Query: 869  VIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC 928
            ++WD+RTTV ++  P ++G + GLCGNFD ++ N+  T +++ +++  +FG+SW  A  C
Sbjct: 1090 LLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA-AVEC 1148

Query: 929  PDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGD 988
            PD     + C LNP R  +A+K+CSIL S VF ICH  VD   FY  C+ D+C C  GGD
Sbjct: 1149 PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGD 1208

Query: 989  CECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1026
            CECFC++V++YA +C + G  V WRTP LCP  CD++N
Sbjct: 1209 CECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1246



 Score =  237 bits (605), Expect = 1e-61
 Identities = 319/1356 (23%), Positives = 478/1356 (35%), Gaps = 232/1356 (17%)

Query: 1288 EINVQCC---ECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTT 1344
            E+  +C    +CV     + T    N T  P    +   PTP+    Q +  +P   T T
Sbjct: 1452 EVTQRCVYLEDCVEPAVWVPTEALGNETLPP----SQGLPTPSDEEPQLSQESP--RTPT 1505

Query: 1345 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1404
              P  TP    T    P   T T  P  +P  TQT    P+  T +  P      T++P 
Sbjct: 1506 HRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPLELTASQLPAGP---TESPA 1561

Query: 1405 STPITTTTTVTP-TPT----PTGTQTPT---------TTPITTTTTVTPTPTPTGTQAPT 1450
            S  +T +    P TP     P   QTPT         TT +T     +P  T +    P 
Sbjct: 1562 SKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPA 1621

Query: 1451 PTAITTTSTVT----------PTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQ----TP 1495
            P     T  VT           TP  P+ T +P++ P+ +   ++ +PT +G+     TP
Sbjct: 1622 PRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTP 1681

Query: 1496 TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPT 1555
              T + + T V P PT   + +  STP+T   T          Q P  +P++T +     
Sbjct: 1682 AVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAE-------QVPV-SPLATRSLEIVL 1732

Query: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-VLITTTTTMTPTPTP------TSTK 1608
             T  G +   + P+ +  +  P P P+    P     + T +   P  TP      T+T 
Sbjct: 1733 STEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATD 1791

Query: 1609 STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAE 1668
                TP  +  +   +   +G    T +P++   T  P  TP     GP     T P+  
Sbjct: 1792 GLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP-----GPKASVITTPLQP 1846

Query: 1669 LTTSNP-------------------PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
              T+ P                   PP    P  + +    L  +T   S + P  E T+
Sbjct: 1847 QATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTA 1906

Query: 1710 TAPPSTPTAPTTTSGG---HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 1766
            +     P   TT         +S P S   S  G PT   T  +S   TP   +     A
Sbjct: 1907 SMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE-LTPATSHPLTPLVAEPEGAQA 1965

Query: 1767 WTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLS 1826
             T  P P S      +    P  S +++   L + +         GT             
Sbjct: 1966 GTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAH---------GTSAGPHLAAEPVDE 2016

Query: 1827 CTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWW 1886
             T E    S P+             T    +ST   P                       
Sbjct: 2017 ATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------------------- 2057

Query: 1887 LCDCFMATCKYNNTVEIVKVECEPPPM--PTCSNGLQPVRVEDPDGCCWHWECDCYCTGW 1944
              DC    C     + + + +  P     P C      VRV   D CC  WEC C C+ +
Sbjct: 2058 --DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIF 2114

Query: 1945 GDPHYVTFDGLYYSYQGNCTYVLVEEISPS-------VDNFGVYIDNYHCDPNDKVSCPR 1997
             D  +VTFDG + +      Y+L +  SP        +D     + + +  P     C  
Sbjct: 2115 PDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLDCKSANLGHLNWPP----FCLV 2168

Query: 1998 TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVL 2057
             L + H   +V I   +      +V V+ Q V  P  +YG  +  +G  Y++  P    +
Sbjct: 2169 MLNMTHLAHQVTIDRFNR-----KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQI 2223

Query: 2058 VSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA---DQWLVN 2114
               +     +            G CG C    ++D  L  G +V   E  A   D W V 
Sbjct: 2224 QWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVP 2283

Query: 2115 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYY 2174
                     SS T+       P    TT   DC  SP  +++ +  F+ CH  VPP+ + 
Sbjct: 2284 ---------SSLTSVGQTRFRPDSCATT---DC--SPCLRMVSNRTFSACHRFVPPESFC 2329

Query: 2175 DACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPA 2234
            +  + D+ ++      C +L  Y A+C + ++C++WR   +  C   C S   YQAC  A
Sbjct: 2330 ELWIRDTKYV---QQPCVALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTA 2384

Query: 2235 EEP--TCKSSS----SQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPRE 2286
             EP  TC+         ++  VL EGC C EGT+ +     +C+    C C     VPR 
Sbjct: 2385 CEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2444

Query: 2287 FGEHFEFDCKNCVC--LEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITV 2344
             GE +      C     +    I+     C       C+  G  +A  +   D CC  TV
Sbjct: 2445 LGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE-VALLLPTKDPCCLGTV 2503

Query: 2345 CKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCE-SKGVCVHGNAEYQPG------- 2396
            C CN +LC+     C  G  + +      CCP Y CE    +C    AE  P        
Sbjct: 2504 CVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLC---EAELVPSCRQDQIL 2560

Query: 2397 ---------SPVYSSKCQDC-----VCTD----KVDNNTL-----LNVIACTHVPC-NTS 2432
                        Y   C DC      C +     V  NT      L    C +  C    
Sbjct: 2561 ITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQ 2620

Query: 2433 CSPGFELME--APGECC--KKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKI 2488
            C  G  L+E  +P  CC  K CE   C               D  + P   C  +   ++
Sbjct: 2621 CGLGTALVEVWSPDRCCPYKSCE---C---------------DCDTIPVPRCHLWEKSQL 2662

Query: 2489 HNQLISSVSNIT-CPNFD---ASICIPGSITFMPNG 2520
              + + SV N+  C  ++   A +C+   +  M  G
Sbjct: 2663 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPG 2698



 Score =  231 bits (589), Expect = 7e-60
 Identities = 190/769 (24%), Positives = 312/769 (40%), Gaps = 164/769 (21%)

Query: 372  LQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGN 431
            ++V LPHV  S  + + + Y I+   +      +       +++ +     G   GLCGN
Sbjct: 230  MRVQLPHVMGSARLQQLAGYVIVRHQSA---FTLAWDGASAVYIKMSPELLGWTHGLCGN 286

Query: 432  FNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDD----PC-SLNIESANYAE 486
             N    DD  T+SG +      F ++W+ Q+               PC   N  +     
Sbjct: 287  NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346

Query: 487  HWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVM 546
              C  L +   PF  CH+ V P  +       T +C ++   LC ++           V 
Sbjct: 347  EQCEALLRP--PFDACHAYVSPLPF-------TASCTSD---LCQSMGD---------VA 385

Query: 547  LWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTF 606
             W                              CR+L+E    C +   P+ G        
Sbjct: 386  TW------------------------------CRALAEYARACAQAGRPLQGW------- 408

Query: 607  LDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIH 666
                                             R   R   +HC++       C A    
Sbjct: 409  ---------------------------------RTQLRQCTVHCKEKAFTYNECIA---- 431

Query: 667  MDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHN 726
                     A+  PRA    +  A      CV GC CP+GL+ +  GGCV   ECPC  +
Sbjct: 432  ------CCPASCHPRASCVDSEIA------CVDGCYCPNGLIFED-GGCVAPAECPCEFH 478

Query: 727  NDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYV 786
              LY  G+ +K DCNTCTC  G+W C+ AVC   CS+ G  H+ TFDG+ Y F   C Y+
Sbjct: 479  GTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYI 538

Query: 787  AVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRT-----------ELKLED 834
                   ++ S G+F++  +N PCG      C +++ + + +            ++ L D
Sbjct: 539  -----LAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFD 593

Query: 835  KHRVVIQRDEGHHVAYTTREVGQ-YLVVESSTGIIVIWDKR-TTVFIKLAPSYKGTVCGL 892
            +++++    +    A+  R +   +L V ++ G+ V++D+    +++++   +     GL
Sbjct: 594  QYKIIPPYTDD---AFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGL 650

Query: 893  CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC-PDVSTNP-EPCSLNPHRRSWAEK 950
            CG F+  + +DF +   +  S+   FGNSWK    C P VS +P +PC ++    S++ +
Sbjct: 651  CGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQ 710

Query: 951  QCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV 1010
             CS+L   +F+ C + + P P++E C  D+C C       C C+ +A YA  C + G  V
Sbjct: 711  ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPV 766

Query: 1011 FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTIN-----GIHSNISVS---YL 1061
             +R     C + C       E    Y PC      TC+ +      G+     +S    +
Sbjct: 767  DFRARLPACALSC-------EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 819

Query: 1062 EGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGAS-VPTEETC 1109
            EGC   CP D  + +     CV  ++C C+ +   YPPG S +P+   C
Sbjct: 820  EGC--ACPPDTYL-DTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 865



 Score =  157 bits (398), Expect = 1e-37
 Identities = 125/396 (31%), Positives = 180/396 (45%), Gaps = 40/396 (10%)

Query: 761  CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG-SFSIITENVP-CGTTGVTCS 818
            C  +G  H  TFDG YY   G  SY  V    G++   G SFSI   N P CG++  TCS
Sbjct: 151  CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 206

Query: 819  KAIKIF-MGRTELKLEDKHRVVIQRDEGHHVAYTTR--EVGQYLVVESSTGIIVIWDKRT 875
            +A+ +F +G  E+ L  +      R +  HV  + R  ++  Y++V   +   + WD  +
Sbjct: 207  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 266

Query: 876  TVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE----APTCPDV 931
             V+IK++P   G   GLCGN +    +D  T    +    ++F +SW+E     P  P  
Sbjct: 267  AVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTT 326

Query: 932  STNPEPCSL--NPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC 989
            S+ P P  L  NP       +QC  L    F  CH+ V P PF  +C  D   C + GD 
Sbjct: 327  SSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LCQSMGDV 384

Query: 990  ECFCSAVASYAQECTKEGACV-FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1047
              +C A+A YA+ C + G  +  WRT    C + C       E  + Y  C      +C 
Sbjct: 385  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC------KEKAFTYNECIACCPASCH 438

Query: 1048 TINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEE 1107
                   +  ++ ++GCY  CP    I+E+    CV   +C C    T YPPG+ V  +E
Sbjct: 439  P-RASCVDSEIACVDGCY--CPNGL-IFEDG--GCVAPAECPCEFHGTLYPPGSVV--KE 490

Query: 1108 TCKSCVCTNS----SQVVCRPE---EGKILNQTQDG 1136
             C +C CT+     S  VC  E    G I   T DG
Sbjct: 491  DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 526



 Score =  119 bits (297), Expect = 5e-26
 Identities = 139/580 (23%), Positives = 226/580 (38%), Gaps = 108/580 (18%)

Query: 1895 CKYNNTV----EIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECD-----CYCTGWG 1945
            C+++ T+     +VK +C      TC++G               WEC        C+  G
Sbjct: 475  CEFHGTLYPPGSVVKEDCNTC---TCTSG--------------KWECSTAVCPAECSVTG 517

Query: 1946 DPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTL-IVRHE 2004
            D H+ TFDG  Y++   C Y+L +  S S   F V + N  C  N   +C +++ ++ H+
Sbjct: 518  DIHFTTFDGRRYTFPATCQYILAK--SRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 575

Query: 2005 TQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN--G 2062
                  + V +      +  ++  +  PY     E+ +    ++     +GV V Y+  G
Sbjct: 576  DPR---RQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632

Query: 2063 LSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCP 2122
            L   +++   R+  +T G CGT    T DD + P G   S  +   + W       P   
Sbjct: 633  LRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV- 690

Query: 2123 HSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC 2182
             S S      V +     +           C ++   +FA C A + P  Y++ C  D+C
Sbjct: 691  -SGSPLDPCDVHLQAASYSV--------QACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 741

Query: 2183 FMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 2242
               G    CA+L  YA LC +  + +D+R     AC + C + +EY  C      TC+  
Sbjct: 742  -RCGQPCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPCGRTCQDL 799

Query: 2243 SSQQ----------NNTVLVEGCFCPEGTMNYAPGFDVCV--KTCGC--VGPDNVPREFG 2288
            +S +          +    VEGC CP  T       D+CV    C C   G D  P   G
Sbjct: 800  ASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-DLCVPRNQCSCHFQGVDYPP---G 855

Query: 2289 EHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCN 2348
            +       +C C +G   + C     S+ P   C     +    VN +D   ++ + +  
Sbjct: 856  DSDIPSLGHCHCKDG--VMSCD----SRAPAAACPAGQVF----VNCSDLHTDLELSRER 905

Query: 2349 TSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA--------------EYQ 2394
            T  C+++  +  L    +   + G  CP      +G+  HG+A              EY 
Sbjct: 906  T--CEQQ--LLNLSVSARGPCLSGCACP------QGLLRHGDACFLPEECPCTWKGKEYF 955

Query: 2395 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434
            PG  V  S C  CVC              CT  PC ++C+
Sbjct: 956  PGDQV-MSPCHTCVCQ--------RGSFQCTLHPCASTCT 986



 Score =  115 bits (289), Expect = 4e-25
 Identities = 109/399 (27%), Positives = 155/399 (38%), Gaps = 49/399 (12%)

Query: 1936 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 1995
            E D  C  WG  H  TFDGLYY   G  +Y LV    P   +F + + N     +   +C
Sbjct: 146  ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 205

Query: 1996 PR--TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE 2053
             R  +L    E +  L K V    M+VQ         LP+   G    Q    YV+   +
Sbjct: 206  SRAVSLFFVGEQEIHLAKEVTHGGMRVQ---------LPH-VMGSARLQQLAGYVIVRHQ 255

Query: 2054 LGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV 2113
                ++++G S             T G CG       DD +  SG++  +       W  
Sbjct: 256  SAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE 315

Query: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHY 2173
              P++P  P +SS  + P +    G     ++       C+ +    F  CHA V P  +
Sbjct: 316  QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRPPFDACHAYVSPLPF 369

Query: 2174 YDACVFDSCFMPGS-SLECASLQAYAALCAQQNICLD-WRNHTHGACLVECP----SHRE 2227
              +C  D C   G  +  C +L  YA  CAQ    L  WR      C V C     ++ E
Sbjct: 370  TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNE 428

Query: 2228 YQACGPAEEPTCKSSSSQQNNTV-LVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 2286
              AC PA   +C   +S  ++ +  V+GC+CP G         +  +  GCV P   P E
Sbjct: 429  CIACCPA---SCHPRASCVDSEIACVDGCYCPNG---------LIFEDGGCVAPAECPCE 476

Query: 2287 F-------GEHFEFDCKNCVCLEGG---SGIICQPKRCS 2315
            F       G   + DC  C C  G    S  +C P  CS
Sbjct: 477  FHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC-PAECS 514



 Score =  109 bits (273), Expect = 3e-23
 Identities = 91/329 (27%), Positives = 145/329 (44%), Gaps = 32/329 (9%)

Query: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGP-GQAEAPAGVESIL 95
           CS  G+ H+ TFDG  + FP  C Y  A     S   F V L+  P G  +  A V+S+ 
Sbjct: 513 CSVTGDIHFTTFDGRRYTFPATCQYILAKS--RSSGTFTVTLQNAPCGLNQDGACVQSVS 570

Query: 96  LTIKDD-----TIYLTRHLAVLNGAVVSTPHYSPGLLIEK-SDAYTKVYSRAGLTLMWNR 149
           + +  D     T+     + + +   +  P+      I + S  + +V +  G+ ++++R
Sbjct: 571 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630

Query: 150 ED-ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSD-GVLFS-PLEFGNMQKINQ--PDV 204
           E   L L++D ++   T GLCG +NG  +  +FLS  GV  S P  FGN  K       +
Sbjct: 631 EGLRLYLQVDQRWVEDTVGLCGTFNG-NTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 689

Query: 205 VCEDPEEEV-APASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
           V   P +        + +  +   +LT E FA C   +   PY   C++D CRC  G  C
Sbjct: 690 VSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRC--GQPC 747

Query: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323
           +C+T+A ++  C    G P ++R    A  P  + +C  +  Y    +PC  TC  L   
Sbjct: 748 LCATLAHYAHLC-RRHGLPVDFR----ARLPACALSCEASKEYSPCVAPCGRTCQDLASP 802

Query: 324 SLC---------EEHRMDGCFCPEGAQAD 343
             C          +  ++GC CP     D
Sbjct: 803 EACGVDGGDDLSRDECVEGCACPPDTYLD 831



 Score = 98.2 bits (243), Expect = 9e-20
 Identities = 152/720 (21%), Positives = 242/720 (33%), Gaps = 105/720 (14%)

Query: 1031 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1090
            CEW Y+ C +  F+TCR      S   V     C P CP  + + +E  ++CV  + C  
Sbjct: 1408 CEWRYDACASPCFQTCRDPRAA-SCRDVPRGRSCVPVCPTPQ-VLDEVTQRCVYLEDC-- 1463

Query: 1091 YVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1150
                    P   VPTE      +  +        EE + L+Q       +     P   +
Sbjct: 1464 ------VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQ-LSQESPRTPTHRPALTPAAPL 1516

Query: 1151 EKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSS----------TVLSTTP 1200
                N     T    ++   T T    P   T +     PT S            +  TP
Sbjct: 1517 TTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1576

Query: 1201 KLCCLWSDWINEDHPSSGSDDGDRETFDGV---CGAPE-DIECRSVKDPHLSLEQLGQKV 1256
            +   L    +    P+ G   G  ET        G+P   +  RS   P           
Sbjct: 1577 ESSSL---PVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFP-------- 1625

Query: 1257 QLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPI 1316
                     L+ K    +  G +P+                 + T +  + T +P+  P+
Sbjct: 1626 ---------LMTKAVTVRGHGSLPV-----------------RTTPLQPSLTASPSSRPV 1659

Query: 1317 TTTTTVTPTPTPTSTQSTTPTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1373
             +   ++ +PT + +     TP  T   + T  P PT   + +  +TP+T   T      
Sbjct: 1660 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGT------ 1713

Query: 1374 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTT-TPIT 1432
                Q P  +P+ T +      T  G +   S P+ +  +  P P P+    P   T + 
Sbjct: 1714 -AAEQVP-VSPLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMA 1770

Query: 1433 TTTTVTPTPTP------TGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPT 1486
            T +   P  TP      T T     T   +  +  P+   +G    T+ P+    T  P 
Sbjct: 1771 TRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAP- 1829

Query: 1487 PTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPI 1546
                   TP P A   TT + P          T+ P  T + V P      TQ   PT I
Sbjct: 1830 -----VATPGPKASVITTPLQP--------QATTLPAQTLSPVLPFTPAAMTQAHPPTHI 1876

Query: 1547 STTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP 1604
            +     T      G   PT+   P+   T    +  P  + T    +++   ++ PT   
Sbjct: 1877 APPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSL-PTSMY 1935

Query: 1605 TSTKS--TTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTS 1662
             S +   T +TP T+         P G Q  T +P+ T+  ++     T           
Sbjct: 1936 GSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDS--MLVL 1993

Query: 1663 TAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST---LPPAIEMTSTAPPSTPTAP 1719
               +AE   ++  P  +      +T+ P   S   LS    L  A+  T+ A  ST   P
Sbjct: 1994 LPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 78/317 (24%), Positives = 124/317 (39%), Gaps = 18/317 (5%)

Query: 35  NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
           ++C  WG  H +TFDG  +   G   Y          + F++ +   P    +P      
Sbjct: 149 SICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRA 208

Query: 95  --LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152
             L  + +  I+L + +    G  V  PH      +++   Y  V  ++  TL W+   A
Sbjct: 209 VSLFFVGEQEIHLAKEVTH-GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASA 267

Query: 153 LMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNM---QKINQP-----D 203
           + +++  +    T GLCG+ N         S G L   + EF +    Q  NQP      
Sbjct: 268 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327

Query: 204 VVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
            +   P  +  P +      +CE LL    F  C   V   P+  +C  D C+  G    
Sbjct: 328 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 386

Query: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323
            C  +AE++R C+ AG     WRT     +    +       Y E  + C  +C H   S
Sbjct: 387 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKA---FTYNECIACCPASC-HPRAS 442

Query: 324 SLCEEHR-MDGCFCPEG 339
            +  E   +DGC+CP G
Sbjct: 443 CVDSEIACVDGCYCPNG 459



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 70/313 (22%), Positives = 118/313 (37%), Gaps = 46/313 (14%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C    C   CT +GD HY TFDGL + + G C   LV+  S S  +F V ++N +C  + 
Sbjct: 976  CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK--STSDVSFSVIVENVNCYSSG 1033

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
             + C + + +      ++       P       ++Q V           ++ G   +V  
Sbjct: 1034 MI-CRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEV---------HTWRVGFFTLVHF 1083

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 2111
            P+  + + ++  +        ++     G CG     T ++   P    ++N +     W
Sbjct: 1084 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1143

Query: 2112 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL--------CQLIKDSLFAQ 2163
               +     CP +                  P   C  +PL        C ++   +F  
Sbjct: 1144 AAVE-----CPDTLD----------------PRDMCVLNPLREPFAKKECSILLSEVFEI 1182

Query: 2164 CHALVPPQHYYDACVFDSC-FMPGSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLV 2220
            CH +V    +Y  C+ D+C    G   EC  AS+ AYA  C Q  + +DWR  T   C  
Sbjct: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLCPY 1240

Query: 2221 ECPSHREYQACGP 2233
            +C    +    GP
Sbjct: 1241 DCDFFNKVLGKGP 1253



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 89/398 (22%), Positives = 145/398 (36%), Gaps = 67/398 (16%)

Query: 752  CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY----------CGQNSSLGS- 800
            C    C   CSI+    ++TFDG +        Y+  Q            C ++++LG  
Sbjct: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHL 2160

Query: 801  ----FSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVG 856
                F ++  N+    T +     I  F  +  + L+     V +        +   + G
Sbjct: 2161 NWPPFCLVMLNM----THLAHQVTIDRFNRKVTVDLQPVWPPVSR------YGFRIEDTG 2210

Query: 857  QYLVVESSTGIIVIW-DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSE 915
               ++ + + I + W      + ++ + + K    GLCG  D  + ND T +D  VV   
Sbjct: 2211 HMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGA 2270

Query: 916  LD---FGNSWKEAPTCPDVSTN---PEPCSLNPHRRSWAEKQCS----ILKSSVFSICHS 965
             D   F +SW+   +   V      P+ C         A   CS    ++ +  FS CH 
Sbjct: 2271 EDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHR 2321

Query: 966  KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYY 1025
             V P+ F E  + D+            C A+  Y   C K   C+ WR  D CP  C   
Sbjct: 2322 FVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2375

Query: 1026 NPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYL----EGCYPRCPKDRPIYEEDLKK 1081
            +    C    EP      +TC+  +GI   +   +     EGC   C +   ++      
Sbjct: 2376 STYQACVTACEPP-----KTCQ--DGILGPLDPEHCQVLGEGCV--CSEGTILHRRHSAL 2426

Query: 1082 CVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQ 1119
            C+   KC C   D+   P A   T  +  S  C +  Q
Sbjct: 2427 CIPEAKCAC--TDSMGVPRALGETWNSSLSGCCQHQCQ 2462



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 66/274 (24%), Positives = 120/274 (43%), Gaps = 43/274 (15%)

Query: 35   NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
            + C+ +G+ HY+TFDG  F F G C                VHL +          VE++
Sbjct: 983  STCTAYGDRHYRTFDGLPFDFVGACK---------------VHLVKSTSDVSFSVIVENV 1027

Query: 95   ------LLTIKDDTIYLTRHLAVLNGAVVSTPHYSP-GLLIEKSDAYT--------KVYS 139
                  ++  K  +I +   L V +     + + SP   L +K + +T          + 
Sbjct: 1028 NCYSSGMICRKFISINVGNSLIVFDD---DSGNPSPESFLDDKQEVHTWRVGFFTLVHFP 1084

Query: 140  RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDG--VLFSPLEFGNM- 196
            +  +TL+W++   + ++   +++    GLCG+++ L++ +E  +     L +P EFG+  
Sbjct: 1085 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFD-LKTINEMRTPENLELTNPQEFGSSW 1143

Query: 197  QKINQPDVVCEDPEEEVAPASCSEHRAECE-RLLTAEAFADCQDLVPLEPYLRACQQDRC 255
              +  PD +  DP +        E  A+ E  +L +E F  C  +V +  +   C  D C
Sbjct: 1144 AAVECPDTL--DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTC 1201

Query: 256  RCPGGD--TCVCSTVAEFSRQCSHAGGRPGNWRT 287
             C  G    C C++V+ ++ QC   G    +WRT
Sbjct: 1202 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRT 1234



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 59/226 (26%), Positives = 84/226 (37%), Gaps = 39/226 (17%)

Query: 413  LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATG---AGFANTWKAQSSCHD--K 467
            + V   + S+ Q  GLCG  +G   +D     G V       A F ++W+  SS     +
Sbjct: 2232 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2291

Query: 468  LDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNED 527
              +  D C+    S       C  +    T F  CH  V P  + +    DT   Q    
Sbjct: 2292 TRFRPDSCATTDCSP------CLRMVSNRT-FSACHRFVPPESFCELWIRDTKYVQQP-- 2342

Query: 528  CLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADS 587
              C AL+ Y   C    V +  WR          CP    FL +  +  Q C +  E   
Sbjct: 2343 --CVALTVYVAMCHKFHVCI-EWRRS------DYCP----FLCSSDSTYQACVTACEPPK 2389

Query: 588  HCLEGF-APVD---------GCGCPDHTFLDEK--GRCVPLAKCSC 621
             C +G   P+D         GC C + T L  +    C+P AKC+C
Sbjct: 2390 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435


>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score =  430 bits (1105), Expect = e-119
 Identities = 243/698 (34%), Positives = 377/698 (54%), Gaps = 39/698 (5%)

Query: 347  TVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQ 406
            +V+L  D ++ V + ++   +L ++ ++  P+   +F + R SS  + V   +GVR+   
Sbjct: 498  SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYD 557

Query: 407  LAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHD 466
                ++L++ +DQ       GLCG FNG   DDF +  G+ E+T   F N+WK  S+C  
Sbjct: 558  REG-LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP 616

Query: 467  KLDWLD-DPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNN 525
             +     DPC +++++A+Y+   CS+L  T   F  C + + P  Y+++C+ D C C   
Sbjct: 617  LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC--G 672

Query: 526  EDCLCAALSSYARACTAKGVML-WGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE 584
            + CLCA L+ YA  C   G+ + +  R   C     SC  S+ +   +  C +TC+ L+ 
Sbjct: 673  QPCLCATLAHYAHLCRRHGLPVDFRARLPACAL---SCEASKEYSPCVAPCGRTCQDLAS 729

Query: 585  ADSHCLEGFAP------VDGCGCPDHTFLDEKGR-CVPLAKCSCYHRGLYLEAGDVVVRQ 637
             ++  ++G         V+GC CP  T+LD +   CVP  +CSC+ +G+    GD  +  
Sbjct: 730  PEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 789

Query: 638  EERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNL-TALATSKPRALSCQTLAAGYY-HT 695
               C C+DG + C   R    +C A ++ ++CS+L T L  S+ R    Q L        
Sbjct: 790  LGHCHCKDGVMSCDS-RAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 848

Query: 696  ECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQA 755
             C+SGC CP GL+  G   C + +ECPC      Y  G ++   C+TC C+RG + CT  
Sbjct: 849  PCLSGCACPQGLLRHG-DACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 907

Query: 756  VCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGV 815
             C  TC+ YG  HY TFDG  +DF G C    V+     ++S  SFS+I ENV C ++G+
Sbjct: 908  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVSFSVIVENVNCYSSGM 962

Query: 816  TCSKAIKIFMGRTELKLEDK------HRVVIQRDEGHHVAYTTREVGQYLVVE-SSTGII 868
             C K I I +G + +  +D          +  + E H     T  VG + +V      I 
Sbjct: 963  ICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVH-----TWRVGFFTLVHFPQEHIT 1017

Query: 869  VIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC 928
            ++WD+RTTV ++  P ++G + GLCGNFD ++ N+  T +++ +++  +FG+SW  A  C
Sbjct: 1018 LLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA-AVEC 1076

Query: 929  PDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGD 988
            PD     + C LNP R  +A+K+CSIL S VF ICH  VD   FY  C+ D+C C  GGD
Sbjct: 1077 PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGD 1136

Query: 989  CECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1026
            CECFC++V++YA +C + G  V WRTP LCP  CD++N
Sbjct: 1137 CECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1174



 Score =  239 bits (610), Expect = 3e-62
 Identities = 318/1356 (23%), Positives = 477/1356 (35%), Gaps = 232/1356 (17%)

Query: 1288 EINVQCC---ECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTT 1344
            E+  +C    +CV     + T    N T  P    +   PTP+    Q +  +P   T T
Sbjct: 1380 EVTQRCVYLEDCVEPAVWVPTEALGNETLPP----SQGLPTPSDEEPQLSQESP--RTPT 1433

Query: 1345 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1404
              P  TP    T    P   T T  P  +P  TQT    P+  T +  P      T++P 
Sbjct: 1434 HRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPLELTASQLPAGP---TESPA 1489

Query: 1405 STPITTTTTVTP-TPT----PTGTQTPT---------TTPITTTTTVTPTPTPTGTQAPT 1450
            S  +T +    P TP     P   QTPT         TT +T     +P  T +    P 
Sbjct: 1490 SKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPA 1549

Query: 1451 PTAITTTSTVT-----------PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ----TP 1495
            P     T  VT             P P+ T +P++ P+ +   ++ +PT +G+     TP
Sbjct: 1550 PRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTP 1609

Query: 1496 TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPT 1555
              T + + T V P PT   + +  STP+T   T          Q P  +P++T +     
Sbjct: 1610 AVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAE-------QVPV-SPLATRSLEIVL 1660

Query: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-VLITTTTTMTPTPTP------TSTK 1608
             T  G +   + P+ +  +  P P P+    P     + T +   P  TP      T+T 
Sbjct: 1661 STEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATD 1719

Query: 1609 STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAE 1668
                TP  +  +   +   +G    T +P++   T  P  TP     GP     T P+  
Sbjct: 1720 GLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP-----GPKASVITTPLQP 1774

Query: 1669 LTTSNP-------------------PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
              T+ P                   PP    P  + +    L  +T   S + P  E T+
Sbjct: 1775 QATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTA 1834

Query: 1710 TAPPSTPTAPTTTSGG---HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 1766
            +     P   TT         +S P S   S  G PT   T  +S   TP   +     A
Sbjct: 1835 SMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE-LTPATSHPLTPLVAEPEGAQA 1893

Query: 1767 WTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLS 1826
             T  P P S      +    P  S +++   L + +         GT             
Sbjct: 1894 GTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAH---------GTSAGPHLAAEPVDE 1944

Query: 1827 CTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWW 1886
             T E    S P+             T    +ST   P                       
Sbjct: 1945 ATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------------------- 1985

Query: 1887 LCDCFMATCKYNNTVEIVKVECEPPPM--PTCSNGLQPVRVEDPDGCCWHWECDCYCTGW 1944
              DC    C     + + + +  P     P C      VRV   D CC  WEC C C+ +
Sbjct: 1986 --DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIF 2042

Query: 1945 GDPHYVTFDGLYYSYQGNCTYVLVEEISPS-------VDNFGVYIDNYHCDPNDKVSCPR 1997
             D  +VTFDG + +      Y+L +  SP        +D     + + +  P     C  
Sbjct: 2043 PDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLDCKSANLGHLNWPP----FCLV 2096

Query: 1998 TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVL 2057
             L + H   +V I   +      +V V+ Q V  P  +YG  +  +G  Y++  P    +
Sbjct: 2097 MLNMTHLAHQVTIDRFNR-----KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQI 2151

Query: 2058 VSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA---DQWLVN 2114
               +     +            G CG C    ++D  L  G +V   E  A   D W V 
Sbjct: 2152 QWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVP 2211

Query: 2115 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYY 2174
                     SS T+       P    TT   DC  SP  +++ +  F+ CH  VPP+ + 
Sbjct: 2212 ---------SSLTSVGQTRFRPDSCATT---DC--SPCLRMVSNRTFSACHRFVPPESFC 2257

Query: 2175 DACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPA 2234
            +  + D+ ++      C +L  Y A+C + ++C++WR   +  C   C S   YQAC  A
Sbjct: 2258 ELWIRDTKYV---QQPCVALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTA 2312

Query: 2235 EEP--TCKSSS----SQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPRE 2286
             EP  TC+         ++  VL EGC C EGT+ +     +C+    C C     VPR 
Sbjct: 2313 CEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2372

Query: 2287 FGEHFEFDCKNCVC--LEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITV 2344
             GE +      C     +    I+     C       C+  G  +A  +   D CC  TV
Sbjct: 2373 LGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE-VALLLPTKDPCCLGTV 2431

Query: 2345 CKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCE-SKGVCVHGNAEYQPG------- 2396
            C CN +LC+     C  G  + +      CCP Y CE    +C    AE  P        
Sbjct: 2432 CVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLC---EAELVPSCRQDQIL 2488

Query: 2397 ---------SPVYSSKCQDC-----VCTD----KVDNNTL-----LNVIACTHVPC-NTS 2432
                        Y   C DC      C +     V  NT      L    C +  C    
Sbjct: 2489 ITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQ 2548

Query: 2433 CSPGFELME--APGECC--KKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKI 2488
            C  G  L+E  +P  CC  K CE   C               D  + P   C  +   ++
Sbjct: 2549 CGLGTALVEVWSPDRCCPYKSCE---C---------------DCDTIPVPRCHLWEKSQL 2590

Query: 2489 HNQLISSVSNIT-CPNFD---ASICIPGSITFMPNG 2520
              + + SV N+  C  ++   A +C+   +  M  G
Sbjct: 2591 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPG 2626



 Score =  231 bits (589), Expect = 7e-60
 Identities = 190/769 (24%), Positives = 312/769 (40%), Gaps = 164/769 (21%)

Query: 372  LQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGN 431
            ++V LPHV  S  + + + Y I+   +      +       +++ +     G   GLCGN
Sbjct: 158  MRVQLPHVMGSARLQQLAGYVIVRHQSA---FTLAWDGASAVYIKMSPELLGWTHGLCGN 214

Query: 432  FNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDD----PC-SLNIESANYAE 486
             N    DD  T+SG +      F ++W+ Q+               PC   N  +     
Sbjct: 215  NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274

Query: 487  HWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVM 546
              C  L +   PF  CH+ V P  +       T +C ++   LC ++           V 
Sbjct: 275  EQCEALLRP--PFDACHAYVSPLPF-------TASCTSD---LCQSMGD---------VA 313

Query: 547  LWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTF 606
             W                              CR+L+E    C +   P+ G        
Sbjct: 314  TW------------------------------CRALAEYARACAQAGRPLQGW------- 336

Query: 607  LDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIH 666
                                             R   R   +HC++       C A    
Sbjct: 337  ---------------------------------RTQLRQCTVHCKEKAFTYNECIA---- 359

Query: 667  MDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHN 726
                     A+  PRA    +  A      CV GC CP+GL+ +  GGCV   ECPC  +
Sbjct: 360  ------CCPASCHPRASCVDSEIA------CVDGCYCPNGLIFED-GGCVAPAECPCEFH 406

Query: 727  NDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYV 786
              LY  G+ +K DCNTCTC  G+W C+ AVC   CS+ G  H+ TFDG+ Y F   C Y+
Sbjct: 407  GTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYI 466

Query: 787  AVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRT-----------ELKLED 834
                   ++ S G+F++  +N PCG      C +++ + + +            ++ L D
Sbjct: 467  -----LAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFD 521

Query: 835  KHRVVIQRDEGHHVAYTTREVGQ-YLVVESSTGIIVIWDKR-TTVFIKLAPSYKGTVCGL 892
            +++++    +    A+  R +   +L V ++ G+ V++D+    +++++   +     GL
Sbjct: 522  QYKIIPPYTDD---AFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGL 578

Query: 893  CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC-PDVSTNP-EPCSLNPHRRSWAEK 950
            CG F+  + +DF +   +  S+   FGNSWK    C P VS +P +PC ++    S++ +
Sbjct: 579  CGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQ 638

Query: 951  QCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV 1010
             CS+L   +F+ C + + P P++E C  D+C C       C C+ +A YA  C + G  V
Sbjct: 639  ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPV 694

Query: 1011 FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTIN-----GIHSNISVS---YL 1061
             +R     C + C       E    Y PC      TC+ +      G+     +S    +
Sbjct: 695  DFRARLPACALSC-------EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 747

Query: 1062 EGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGAS-VPTEETC 1109
            EGC   CP D  + +     CV  ++C C+ +   YPPG S +P+   C
Sbjct: 748  EGC--ACPPDTYL-DTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 793



 Score =  157 bits (398), Expect = 1e-37
 Identities = 125/396 (31%), Positives = 180/396 (45%), Gaps = 40/396 (10%)

Query: 761  CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG-SFSIITENVP-CGTTGVTCS 818
            C  +G  H  TFDG YY   G  SY  V    G++   G SFSI   N P CG++  TCS
Sbjct: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 134

Query: 819  KAIKIF-MGRTELKLEDKHRVVIQRDEGHHVAYTTR--EVGQYLVVESSTGIIVIWDKRT 875
            +A+ +F +G  E+ L  +      R +  HV  + R  ++  Y++V   +   + WD  +
Sbjct: 135  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 194

Query: 876  TVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE----APTCPDV 931
             V+IK++P   G   GLCGN +    +D  T    +    ++F +SW+E     P  P  
Sbjct: 195  AVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTT 254

Query: 932  STNPEPCSL--NPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC 989
            S+ P P  L  NP       +QC  L    F  CH+ V P PF  +C  D   C + GD 
Sbjct: 255  SSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LCQSMGDV 312

Query: 990  ECFCSAVASYAQECTKEGACV-FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1047
              +C A+A YA+ C + G  +  WRT    C + C       E  + Y  C      +C 
Sbjct: 313  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC------KEKAFTYNECIACCPASCH 366

Query: 1048 TINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEE 1107
                   +  ++ ++GCY  CP    I+E+    CV   +C C    T YPPG+ V  +E
Sbjct: 367  P-RASCVDSEIACVDGCY--CPNGL-IFEDG--GCVAPAECPCEFHGTLYPPGSVV--KE 418

Query: 1108 TCKSCVCTNS----SQVVCRPE---EGKILNQTQDG 1136
             C +C CT+     S  VC  E    G I   T DG
Sbjct: 419  DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 454



 Score =  119 bits (297), Expect = 5e-26
 Identities = 139/580 (23%), Positives = 226/580 (38%), Gaps = 108/580 (18%)

Query: 1895 CKYNNTV----EIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECD-----CYCTGWG 1945
            C+++ T+     +VK +C      TC++G               WEC        C+  G
Sbjct: 403  CEFHGTLYPPGSVVKEDCNTC---TCTSG--------------KWECSTAVCPAECSVTG 445

Query: 1946 DPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTL-IVRHE 2004
            D H+ TFDG  Y++   C Y+L +  S S   F V + N  C  N   +C +++ ++ H+
Sbjct: 446  DIHFTTFDGRRYTFPATCQYILAK--SRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 503

Query: 2005 TQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN--G 2062
                  + V +      +  ++  +  PY     E+ +    ++     +GV V Y+  G
Sbjct: 504  DPR---RQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 560

Query: 2063 LSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCP 2122
            L   +++   R+  +T G CGT    T DD + P G   S  +   + W       P   
Sbjct: 561  LRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV- 618

Query: 2123 HSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC 2182
             S S      V +     +           C ++   +FA C A + P  Y++ C  D+C
Sbjct: 619  -SGSPLDPCDVHLQAASYSV--------QACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669

Query: 2183 FMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 2242
               G    CA+L  YA LC +  + +D+R     AC + C + +EY  C      TC+  
Sbjct: 670  -RCGQPCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPCGRTCQDL 727

Query: 2243 SSQQ----------NNTVLVEGCFCPEGTMNYAPGFDVCV--KTCGC--VGPDNVPREFG 2288
            +S +          +    VEGC CP  T       D+CV    C C   G D  P   G
Sbjct: 728  ASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-DLCVPRNQCSCHFQGVDYPP---G 783

Query: 2289 EHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCN 2348
            +       +C C +G   + C     S+ P   C     +    VN +D   ++ + +  
Sbjct: 784  DSDIPSLGHCHCKDG--VMSCD----SRAPAAACPAGQVF----VNCSDLHTDLELSRER 833

Query: 2349 TSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA--------------EYQ 2394
            T  C+++  +  L    +   + G  CP      +G+  HG+A              EY 
Sbjct: 834  T--CEQQ--LLNLSVSARGPCLSGCACP------QGLLRHGDACFLPEECPCTWKGKEYF 883

Query: 2395 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434
            PG  V  S C  CVC              CT  PC ++C+
Sbjct: 884  PGDQV-MSPCHTCVCQ--------RGSFQCTLHPCASTCT 914



 Score =  115 bits (289), Expect = 4e-25
 Identities = 109/399 (27%), Positives = 155/399 (38%), Gaps = 49/399 (12%)

Query: 1936 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 1995
            E D  C  WG  H  TFDGLYY   G  +Y LV    P   +F + + N     +   +C
Sbjct: 74   ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 133

Query: 1996 PR--TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE 2053
             R  +L    E +  L K V    M+VQ         LP+   G    Q    YV+   +
Sbjct: 134  SRAVSLFFVGEQEIHLAKEVTHGGMRVQ---------LPH-VMGSARLQQLAGYVIVRHQ 183

Query: 2054 LGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV 2113
                ++++G S             T G CG       DD +  SG++  +       W  
Sbjct: 184  SAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE 243

Query: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHY 2173
              P++P  P +SS  + P +    G     ++       C+ +    F  CHA V P  +
Sbjct: 244  QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRPPFDACHAYVSPLPF 297

Query: 2174 YDACVFDSCFMPGS-SLECASLQAYAALCAQQNICLD-WRNHTHGACLVECP----SHRE 2227
              +C  D C   G  +  C +L  YA  CAQ    L  WR      C V C     ++ E
Sbjct: 298  TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNE 356

Query: 2228 YQACGPAEEPTCKSSSSQQNNTV-LVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 2286
              AC PA   +C   +S  ++ +  V+GC+CP G         +  +  GCV P   P E
Sbjct: 357  CIACCPA---SCHPRASCVDSEIACVDGCYCPNG---------LIFEDGGCVAPAECPCE 404

Query: 2287 F-------GEHFEFDCKNCVCLEGG---SGIICQPKRCS 2315
            F       G   + DC  C C  G    S  +C P  CS
Sbjct: 405  FHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC-PAECS 442



 Score =  109 bits (273), Expect = 3e-23
 Identities = 91/329 (27%), Positives = 145/329 (44%), Gaps = 32/329 (9%)

Query: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGP-GQAEAPAGVESIL 95
           CS  G+ H+ TFDG  + FP  C Y  A     S   F V L+  P G  +  A V+S+ 
Sbjct: 441 CSVTGDIHFTTFDGRRYTFPATCQYILAKS--RSSGTFTVTLQNAPCGLNQDGACVQSVS 498

Query: 96  LTIKDD-----TIYLTRHLAVLNGAVVSTPHYSPGLLIEK-SDAYTKVYSRAGLTLMWNR 149
           + +  D     T+     + + +   +  P+      I + S  + +V +  G+ ++++R
Sbjct: 499 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558

Query: 150 ED-ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSD-GVLFS-PLEFGNMQKINQ--PDV 204
           E   L L++D ++   T GLCG +NG  +  +FLS  GV  S P  FGN  K       +
Sbjct: 559 EGLRLYLQVDQRWVEDTVGLCGTFNG-NTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 617

Query: 205 VCEDPEEEV-APASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
           V   P +        + +  +   +LT E FA C   +   PY   C++D CRC  G  C
Sbjct: 618 VSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRC--GQPC 675

Query: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323
           +C+T+A ++  C    G P ++R    A  P  + +C  +  Y    +PC  TC  L   
Sbjct: 676 LCATLAHYAHLC-RRHGLPVDFR----ARLPACALSCEASKEYSPCVAPCGRTCQDLASP 730

Query: 324 SLC---------EEHRMDGCFCPEGAQAD 343
             C          +  ++GC CP     D
Sbjct: 731 EACGVDGGDDLSRDECVEGCACPPDTYLD 759



 Score =  102 bits (255), Expect = 4e-21
 Identities = 154/720 (21%), Positives = 244/720 (33%), Gaps = 105/720 (14%)

Query: 1031 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1090
            CEW Y+ C +  F+TCR      S   V  +EGC P CP  + + +E  ++CV  + C  
Sbjct: 1336 CEWRYDACASPCFQTCRDPRAA-SCRDVPRVEGCVPVCPTPQ-VLDEVTQRCVYLEDC-- 1391

Query: 1091 YVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1150
                    P   VPTE      +  +        EE + L+Q       +     P   +
Sbjct: 1392 ------VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQ-LSQESPRTPTHRPALTPAAPL 1444

Query: 1151 EKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSS----------TVLSTTP 1200
                N     T    ++   T T    P   T +     PT S            +  TP
Sbjct: 1445 TTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1504

Query: 1201 KLCCLWSDWINEDHPSSGSDDGDRETFDGV---CGAPE-DIECRSVKDPHLSLEQLGQKV 1256
            +   L    +    P+ G   G  ET        G+P   +  RS   P           
Sbjct: 1505 ESSSL---PVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFP-------- 1553

Query: 1257 QLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPI 1316
                     L+ K    +  G +P+                 + T    + T +P+  P+
Sbjct: 1554 ---------LMTKAVTVRGHGSLPV-----------------RTTPPQPSLTASPSSRPV 1587

Query: 1317 TTTTTVTPTPTPTSTQSTTPTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1373
             +   ++ +PT + +     TP  T   + T  P PT   + +  +TP+T   T      
Sbjct: 1588 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGT------ 1641

Query: 1374 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTT-TPIT 1432
                Q P  +P+ T +      T  G +   S P+ +  +  P P P+    P   T + 
Sbjct: 1642 -AAEQVP-VSPLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMA 1698

Query: 1433 TTTTVTPTPTP------TGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPT 1486
            T +   P  TP      T T     T   +  +  P+   +G    T+ P+    T  P 
Sbjct: 1699 TRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAP- 1757

Query: 1487 PTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPI 1546
                   TP P A   TT + P          T+ P  T + V P      TQ   PT I
Sbjct: 1758 -----VATPGPKASVITTPLQP--------QATTLPAQTLSPVLPFTPAAMTQAHPPTHI 1804

Query: 1547 STTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP 1604
            +     T      G   PT+   P+   T    +  P  + T    +++   ++ PT   
Sbjct: 1805 APPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSL-PTSMY 1863

Query: 1605 TSTKS--TTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTS 1662
             S +   T +TP T+         P G Q  T +P+ T+  ++     T           
Sbjct: 1864 GSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDS--MLVL 1921

Query: 1663 TAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST---LPPAIEMTSTAPPSTPTAP 1719
               +AE   ++  P  +      +T+ P   S   LS    L  A+  T+ A  ST   P
Sbjct: 1922 LPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 1981



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 78/317 (24%), Positives = 124/317 (39%), Gaps = 18/317 (5%)

Query: 35  NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
           ++C  WG  H +TFDG  +   G   Y          + F++ +   P    +P      
Sbjct: 77  SICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRA 136

Query: 95  --LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152
             L  + +  I+L + +    G  V  PH      +++   Y  V  ++  TL W+   A
Sbjct: 137 VSLFFVGEQEIHLAKEVTH-GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASA 195

Query: 153 LMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNM---QKINQP-----D 203
           + +++  +    T GLCG+ N         S G L   + EF +    Q  NQP      
Sbjct: 196 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 255

Query: 204 VVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
            +   P  +  P +      +CE LL    F  C   V   P+  +C  D C+  G    
Sbjct: 256 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 314

Query: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323
            C  +AE++R C+ AG     WRT     +    +       Y E  + C  +C H   S
Sbjct: 315 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKA---FTYNECIACCPASC-HPRAS 370

Query: 324 SLCEEHR-MDGCFCPEG 339
            +  E   +DGC+CP G
Sbjct: 371 CVDSEIACVDGCYCPNG 387



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 70/313 (22%), Positives = 118/313 (37%), Gaps = 46/313 (14%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C    C   CT +GD HY TFDGL + + G C   LV+  S S  +F V ++N +C  + 
Sbjct: 904  CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK--STSDVSFSVIVENVNCYSSG 961

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
             + C + + +      ++       P       ++Q V           ++ G   +V  
Sbjct: 962  MI-CRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEV---------HTWRVGFFTLVHF 1011

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 2111
            P+  + + ++  +        ++     G CG     T ++   P    ++N +     W
Sbjct: 1012 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1071

Query: 2112 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL--------CQLIKDSLFAQ 2163
               +     CP +                  P   C  +PL        C ++   +F  
Sbjct: 1072 AAVE-----CPDTLD----------------PRDMCVLNPLREPFAKKECSILLSEVFEI 1110

Query: 2164 CHALVPPQHYYDACVFDSC-FMPGSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLV 2220
            CH +V    +Y  C+ D+C    G   EC  AS+ AYA  C Q  + +DWR  T   C  
Sbjct: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLCPY 1168

Query: 2221 ECPSHREYQACGP 2233
            +C    +    GP
Sbjct: 1169 DCDFFNKVLGKGP 1181



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 89/398 (22%), Positives = 145/398 (36%), Gaps = 67/398 (16%)

Query: 752  CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY----------CGQNSSLGS- 800
            C    C   CSI+    ++TFDG +        Y+  Q            C ++++LG  
Sbjct: 2030 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHL 2088

Query: 801  ----FSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVG 856
                F ++  N+    T +     I  F  +  + L+     V +        +   + G
Sbjct: 2089 NWPPFCLVMLNM----THLAHQVTIDRFNRKVTVDLQPVWPPVSR------YGFRIEDTG 2138

Query: 857  QYLVVESSTGIIVIW-DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSE 915
               ++ + + I + W      + ++ + + K    GLCG  D  + ND T +D  VV   
Sbjct: 2139 HMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGA 2198

Query: 916  LD---FGNSWKEAPTCPDVSTN---PEPCSLNPHRRSWAEKQCS----ILKSSVFSICHS 965
             D   F +SW+   +   V      P+ C         A   CS    ++ +  FS CH 
Sbjct: 2199 EDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHR 2249

Query: 966  KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYY 1025
             V P+ F E  + D+            C A+  Y   C K   C+ WR  D CP  C   
Sbjct: 2250 FVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2303

Query: 1026 NPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYL----EGCYPRCPKDRPIYEEDLKK 1081
            +    C    EP      +TC+  +GI   +   +     EGC   C +   ++      
Sbjct: 2304 STYQACVTACEPP-----KTCQ--DGILGPLDPEHCQVLGEGCV--CSEGTILHRRHSAL 2354

Query: 1082 CVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQ 1119
            C+   KC C   D+   P A   T  +  S  C +  Q
Sbjct: 2355 CIPEAKCAC--TDSMGVPRALGETWNSSLSGCCQHQCQ 2390



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 66/274 (24%), Positives = 120/274 (43%), Gaps = 43/274 (15%)

Query: 35   NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
            + C+ +G+ HY+TFDG  F F G C                VHL +          VE++
Sbjct: 911  STCTAYGDRHYRTFDGLPFDFVGACK---------------VHLVKSTSDVSFSVIVENV 955

Query: 95   ------LLTIKDDTIYLTRHLAVLNGAVVSTPHYSP-GLLIEKSDAYT--------KVYS 139
                  ++  K  +I +   L V +     + + SP   L +K + +T          + 
Sbjct: 956  NCYSSGMICRKFISINVGNSLIVFDD---DSGNPSPESFLDDKQEVHTWRVGFFTLVHFP 1012

Query: 140  RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDG--VLFSPLEFGNM- 196
            +  +TL+W++   + ++   +++    GLCG+++ L++ +E  +     L +P EFG+  
Sbjct: 1013 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFD-LKTINEMRTPENLELTNPQEFGSSW 1071

Query: 197  QKINQPDVVCEDPEEEVAPASCSEHRAECE-RLLTAEAFADCQDLVPLEPYLRACQQDRC 255
              +  PD +  DP +        E  A+ E  +L +E F  C  +V +  +   C  D C
Sbjct: 1072 AAVECPDTL--DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTC 1129

Query: 256  RCPGGD--TCVCSTVAEFSRQCSHAGGRPGNWRT 287
             C  G    C C++V+ ++ QC   G    +WRT
Sbjct: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRT 1162



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 59/226 (26%), Positives = 84/226 (37%), Gaps = 39/226 (17%)

Query: 413  LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATG---AGFANTWKAQSSCHD--K 467
            + V   + S+ Q  GLCG  +G   +D     G V       A F ++W+  SS     +
Sbjct: 2160 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2219

Query: 468  LDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNED 527
              +  D C+    S       C  +    T F  CH  V P  + +    DT   Q    
Sbjct: 2220 TRFRPDSCATTDCSP------CLRMVSNRT-FSACHRFVPPESFCELWIRDTKYVQQP-- 2270

Query: 528  CLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADS 587
              C AL+ Y   C    V +  WR          CP    FL +  +  Q C +  E   
Sbjct: 2271 --CVALTVYVAMCHKFHVCI-EWRRS------DYCP----FLCSSDSTYQACVTACEPPK 2317

Query: 588  HCLEGF-APVD---------GCGCPDHTFLDEK--GRCVPLAKCSC 621
             C +G   P+D         GC C + T L  +    C+P AKC+C
Sbjct: 2318 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2363


>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score =  430 bits (1105), Expect = e-119
 Identities = 243/698 (34%), Positives = 377/698 (54%), Gaps = 39/698 (5%)

Query: 347  TVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQ 406
            +V+L  D ++ V + ++   +L ++ ++  P+   +F + R SS  + V   +GVR+   
Sbjct: 570  SVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYD 629

Query: 407  LAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHD 466
                ++L++ +DQ       GLCG FNG   DDF +  G+ E+T   F N+WK  S+C  
Sbjct: 630  REG-LRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSP 688

Query: 467  KLDWLD-DPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNN 525
             +     DPC +++++A+Y+   CS+L  T   F  C + + P  Y+++C+ D C C   
Sbjct: 689  LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC--G 744

Query: 526  EDCLCAALSSYARACTAKGVML-WGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE 584
            + CLCA L+ YA  C   G+ + +  R   C     SC  S+ +   +  C +TC+ L+ 
Sbjct: 745  QPCLCATLAHYAHLCRRHGLPVDFRARLPACAL---SCEASKEYSPCVAPCGRTCQDLAS 801

Query: 585  ADSHCLEGFAP------VDGCGCPDHTFLDEKGR-CVPLAKCSCYHRGLYLEAGDVVVRQ 637
             ++  ++G         V+GC CP  T+LD +   CVP  +CSC+ +G+    GD  +  
Sbjct: 802  PEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPS 861

Query: 638  EERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNL-TALATSKPRALSCQTLAAGYY-HT 695
               C C+DG + C   R    +C A ++ ++CS+L T L  S+ R    Q L        
Sbjct: 862  LGHCHCKDGVMSCDS-RAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARG 920

Query: 696  ECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQA 755
             C+SGC CP GL+  G   C + +ECPC      Y  G ++   C+TC C+RG + CT  
Sbjct: 921  PCLSGCACPQGLLRHG-DACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLH 979

Query: 756  VCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGV 815
             C  TC+ YG  HY TFDG  +DF G C    V+     ++S  SFS+I ENV C ++G+
Sbjct: 980  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK-----STSDVSFSVIVENVNCYSSGM 1034

Query: 816  TCSKAIKIFMGRTELKLEDK------HRVVIQRDEGHHVAYTTREVGQYLVVE-SSTGII 868
             C K I I +G + +  +D          +  + E H     T  VG + +V      I 
Sbjct: 1035 ICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVH-----TWRVGFFTLVHFPQEHIT 1089

Query: 869  VIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC 928
            ++WD+RTTV ++  P ++G + GLCGNFD ++ N+  T +++ +++  +FG+SW  A  C
Sbjct: 1090 LLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWA-AVEC 1148

Query: 929  PDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGD 988
            PD     + C LNP R  +A+K+CSIL S VF ICH  VD   FY  C+ D+C C  GGD
Sbjct: 1149 PDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGD 1208

Query: 989  CECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1026
            CECFC++V++YA +C + G  V WRTP LCP  CD++N
Sbjct: 1209 CECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFN 1246



 Score =  239 bits (610), Expect = 3e-62
 Identities = 318/1356 (23%), Positives = 477/1356 (35%), Gaps = 232/1356 (17%)

Query: 1288 EINVQCC---ECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTT 1344
            E+  +C    +CV     + T    N T  P    +   PTP+    Q +  +P   T T
Sbjct: 1452 EVTQRCVYLEDCVEPAVWVPTEALGNETLPP----SQGLPTPSDEEPQLSQESP--RTPT 1505

Query: 1345 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1404
              P  TP    T    P   T T  P  +P  TQT    P+  T +  P      T++P 
Sbjct: 1506 HRPALTPAAPLTTALNP-PVTATEEPVVSPGPTQTTLQQPLELTASQLPAGP---TESPA 1561

Query: 1405 STPITTTTTVTP-TPT----PTGTQTPT---------TTPITTTTTVTPTPTPTGTQAPT 1450
            S  +T +    P TP     P   QTPT         TT +T     +P  T +    P 
Sbjct: 1562 SKGVTASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPA 1621

Query: 1451 PTAITTTSTVT-----------PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ----TP 1495
            P     T  VT             P P+ T +P++ P+ +   ++ +PT +G+     TP
Sbjct: 1622 PRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTP 1681

Query: 1496 TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPT 1555
              T + + T V P PT   + +  STP+T   T          Q P  +P++T +     
Sbjct: 1682 AVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAE-------QVPV-SPLATRSLEIVL 1732

Query: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-VLITTTTTMTPTPTP------TSTK 1608
             T  G +   + P+ +  +  P P P+    P     + T +   P  TP      T+T 
Sbjct: 1733 STEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMATRSPALPPETPAAASLSTATD 1791

Query: 1609 STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAE 1668
                TP  +  +   +   +G    T +P++   T  P  TP     GP     T P+  
Sbjct: 1792 GLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP-----GPKASVITTPLQP 1846

Query: 1669 LTTSNP-------------------PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
              T+ P                   PP    P  + +    L  +T   S + P  E T+
Sbjct: 1847 QATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTA 1906

Query: 1710 TAPPSTPTAPTTTSGG---HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 1766
            +     P   TT         +S P S   S  G PT   T  +S   TP   +     A
Sbjct: 1907 SMVSVVPRKSTTGKVAILSKQVSLPTSMYGSAEGGPTE-LTPATSHPLTPLVAEPEGAQA 1965

Query: 1767 WTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLS 1826
             T  P P S      +    P  S +++   L + +         GT             
Sbjct: 1966 GTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAH---------GTSAGPHLAAEPVDE 2016

Query: 1827 CTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWW 1886
             T E    S P+             T    +ST   P                       
Sbjct: 2017 ATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVPIAEQ------------------- 2057

Query: 1887 LCDCFMATCKYNNTVEIVKVECEPPPM--PTCSNGLQPVRVEDPDGCCWHWECDCYCTGW 1944
              DC    C     + + + +  P     P C      VRV   D CC  WEC C C+ +
Sbjct: 2058 --DCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGG-DRCCPLWECACRCSIF 2114

Query: 1945 GDPHYVTFDGLYYSYQGNCTYVLVEEISPS-------VDNFGVYIDNYHCDPNDKVSCPR 1997
             D  +VTFDG + +      Y+L +  SP        +D     + + +  P     C  
Sbjct: 2115 PDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLDCKSANLGHLNWPP----FCLV 2168

Query: 1998 TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVL 2057
             L + H   +V I   +      +V V+ Q V  P  +YG  +  +G  Y++  P    +
Sbjct: 2169 MLNMTHLAHQVTIDRFNR-----KVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQI 2223

Query: 2058 VSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAA---DQWLVN 2114
               +     +            G CG C    ++D  L  G +V   E  A   D W V 
Sbjct: 2224 QWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVP 2283

Query: 2115 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYY 2174
                     SS T+       P    TT   DC  SP  +++ +  F+ CH  VPP+ + 
Sbjct: 2284 ---------SSLTSVGQTRFRPDSCATT---DC--SPCLRMVSNRTFSACHRFVPPESFC 2329

Query: 2175 DACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPA 2234
            +  + D+ ++      C +L  Y A+C + ++C++WR   +  C   C S   YQAC  A
Sbjct: 2330 ELWIRDTKYV---QQPCVALTVYVAMCHKFHVCIEWRRSDY--CPFLCSSDSTYQACVTA 2384

Query: 2235 EEP--TCKSSS----SQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVGPDNVPRE 2286
             EP  TC+         ++  VL EGC C EGT+ +     +C+    C C     VPR 
Sbjct: 2385 CEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2444

Query: 2287 FGEHFEFDCKNCVC--LEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITV 2344
             GE +      C     +    I+     C       C+  G  +A  +   D CC  TV
Sbjct: 2445 LGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE-VALLLPTKDPCCLGTV 2503

Query: 2345 CKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCE-SKGVCVHGNAEYQPG------- 2396
            C CN +LC+     C  G  + +      CCP Y CE    +C    AE  P        
Sbjct: 2504 CVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLC---EAELVPSCRQDQIL 2560

Query: 2397 ---------SPVYSSKCQDC-----VCTD----KVDNNTL-----LNVIACTHVPC-NTS 2432
                        Y   C DC      C +     V  NT      L    C +  C    
Sbjct: 2561 ITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQ 2620

Query: 2433 CSPGFELME--APGECC--KKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKI 2488
            C  G  L+E  +P  CC  K CE   C               D  + P   C  +   ++
Sbjct: 2621 CGLGTALVEVWSPDRCCPYKSCE---C---------------DCDTIPVPRCHLWEKSQL 2662

Query: 2489 HNQLISSVSNIT-CPNFD---ASICIPGSITFMPNG 2520
              + + SV N+  C  ++   A +C+   +  M  G
Sbjct: 2663 DEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPG 2698



 Score =  231 bits (589), Expect = 7e-60
 Identities = 190/769 (24%), Positives = 312/769 (40%), Gaps = 164/769 (21%)

Query: 372  LQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGN 431
            ++V LPHV  S  + + + Y I+   +      +       +++ +     G   GLCGN
Sbjct: 230  MRVQLPHVMGSARLQQLAGYVIVRHQSA---FTLAWDGASAVYIKMSPELLGWTHGLCGN 286

Query: 432  FNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDD----PC-SLNIESANYAE 486
             N    DD  T+SG +      F ++W+ Q+               PC   N  +     
Sbjct: 287  NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346

Query: 487  HWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVM 546
              C  L +   PF  CH+ V P  +       T +C ++   LC ++           V 
Sbjct: 347  EQCEALLRP--PFDACHAYVSPLPF-------TASCTSD---LCQSMGD---------VA 385

Query: 547  LWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTF 606
             W                              CR+L+E    C +   P+ G        
Sbjct: 386  TW------------------------------CRALAEYARACAQAGRPLQGW------- 408

Query: 607  LDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIH 666
                                             R   R   +HC++       C A    
Sbjct: 409  ---------------------------------RTQLRQCTVHCKEKAFTYNECIA---- 431

Query: 667  MDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHN 726
                     A+  PRA    +  A      CV GC CP+GL+ +  GGCV   ECPC  +
Sbjct: 432  ------CCPASCHPRASCVDSEIA------CVDGCYCPNGLIFED-GGCVAPAECPCEFH 478

Query: 727  NDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYV 786
              LY  G+ +K DCNTCTC  G+W C+ AVC   CS+ G  H+ TFDG+ Y F   C Y+
Sbjct: 479  GTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYI 538

Query: 787  AVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRT-----------ELKLED 834
                   ++ S G+F++  +N PCG      C +++ + + +            ++ L D
Sbjct: 539  -----LAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFD 593

Query: 835  KHRVVIQRDEGHHVAYTTREVGQ-YLVVESSTGIIVIWDKR-TTVFIKLAPSYKGTVCGL 892
            +++++    +    A+  R +   +L V ++ G+ V++D+    +++++   +     GL
Sbjct: 594  QYKIIPPYTDD---AFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGL 650

Query: 893  CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC-PDVSTNP-EPCSLNPHRRSWAEK 950
            CG F+  + +DF +   +  S+   FGNSWK    C P VS +P +PC ++    S++ +
Sbjct: 651  CGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQ 710

Query: 951  QCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV 1010
             CS+L   +F+ C + + P P++E C  D+C C       C C+ +A YA  C + G  V
Sbjct: 711  ACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ----PCLCATLAHYAHLCRRHGLPV 766

Query: 1011 FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTIN-----GIHSNISVS---YL 1061
             +R     C + C       E    Y PC      TC+ +      G+     +S    +
Sbjct: 767  DFRARLPACALSC-------EASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 819

Query: 1062 EGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGAS-VPTEETC 1109
            EGC   CP D  + +     CV  ++C C+ +   YPPG S +P+   C
Sbjct: 820  EGC--ACPPDTYL-DTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHC 865



 Score =  157 bits (398), Expect = 1e-37
 Identities = 125/396 (31%), Positives = 180/396 (45%), Gaps = 40/396 (10%)

Query: 761  CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG-SFSIITENVP-CGTTGVTCS 818
            C  +G  H  TFDG YY   G  SY  V    G++   G SFSI   N P CG++  TCS
Sbjct: 151  CRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQCGSSPYTCS 206

Query: 819  KAIKIF-MGRTELKLEDKHRVVIQRDEGHHVAYTTR--EVGQYLVVESSTGIIVIWDKRT 875
            +A+ +F +G  E+ L  +      R +  HV  + R  ++  Y++V   +   + WD  +
Sbjct: 207  RAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS 266

Query: 876  TVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE----APTCPDV 931
             V+IK++P   G   GLCGN +    +D  T    +    ++F +SW+E     P  P  
Sbjct: 267  AVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTT 326

Query: 932  STNPEPCSL--NPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC 989
            S+ P P  L  NP       +QC  L    F  CH+ V P PF  +C  D   C + GD 
Sbjct: 327  SSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD--LCQSMGDV 384

Query: 990  ECFCSAVASYAQECTKEGACV-FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1047
              +C A+A YA+ C + G  +  WRT    C + C       E  + Y  C      +C 
Sbjct: 385  ATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC------KEKAFTYNECIACCPASCH 438

Query: 1048 TINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEE 1107
                   +  ++ ++GCY  CP    I+E+    CV   +C C    T YPPG+ V  +E
Sbjct: 439  P-RASCVDSEIACVDGCY--CPNGL-IFEDG--GCVAPAECPCEFHGTLYPPGSVV--KE 490

Query: 1108 TCKSCVCTNS----SQVVCRPE---EGKILNQTQDG 1136
             C +C CT+     S  VC  E    G I   T DG
Sbjct: 491  DCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDG 526



 Score =  119 bits (297), Expect = 5e-26
 Identities = 139/580 (23%), Positives = 226/580 (38%), Gaps = 108/580 (18%)

Query: 1895 CKYNNTV----EIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECD-----CYCTGWG 1945
            C+++ T+     +VK +C      TC++G               WEC        C+  G
Sbjct: 475  CEFHGTLYPPGSVVKEDCNTC---TCTSG--------------KWECSTAVCPAECSVTG 517

Query: 1946 DPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTL-IVRHE 2004
            D H+ TFDG  Y++   C Y+L +  S S   F V + N  C  N   +C +++ ++ H+
Sbjct: 518  DIHFTTFDGRRYTFPATCQYILAK--SRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 575

Query: 2005 TQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN--G 2062
                  + V +      +  ++  +  PY     E+ +    ++     +GV V Y+  G
Sbjct: 576  DPR---RQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREG 632

Query: 2063 LSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCP 2122
            L   +++   R+  +T G CGT    T DD + P G   S  +   + W       P   
Sbjct: 633  LRLYLQVD-QRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLV- 690

Query: 2123 HSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSC 2182
             S S      V +     +           C ++   +FA C A + P  Y++ C  D+C
Sbjct: 691  -SGSPLDPCDVHLQAASYSV--------QACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 741

Query: 2183 FMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 2242
               G    CA+L  YA LC +  + +D+R     AC + C + +EY  C      TC+  
Sbjct: 742  -RCGQPCLCATLAHYAHLCRRHGLPVDFRARL-PACALSCEASKEYSPCVAPCGRTCQDL 799

Query: 2243 SSQQ----------NNTVLVEGCFCPEGTMNYAPGFDVCV--KTCGC--VGPDNVPREFG 2288
            +S +          +    VEGC CP  T       D+CV    C C   G D  P   G
Sbjct: 800  ASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQA-DLCVPRNQCSCHFQGVDYPP---G 855

Query: 2289 EHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCN 2348
            +       +C C +G   + C     S+ P   C     +    VN +D   ++ + +  
Sbjct: 856  DSDIPSLGHCHCKDG--VMSCD----SRAPAAACPAGQVF----VNCSDLHTDLELSRER 905

Query: 2349 TSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA--------------EYQ 2394
            T  C+++  +  L    +   + G  CP      +G+  HG+A              EY 
Sbjct: 906  T--CEQQ--LLNLSVSARGPCLSGCACP------QGLLRHGDACFLPEECPCTWKGKEYF 955

Query: 2395 PGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434
            PG  V  S C  CVC              CT  PC ++C+
Sbjct: 956  PGDQV-MSPCHTCVCQ--------RGSFQCTLHPCASTCT 986



 Score =  115 bits (289), Expect = 4e-25
 Identities = 109/399 (27%), Positives = 155/399 (38%), Gaps = 49/399 (12%)

Query: 1936 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 1995
            E D  C  WG  H  TFDGLYY   G  +Y LV    P   +F + + N     +   +C
Sbjct: 146  ERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTC 205

Query: 1996 PR--TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPE 2053
             R  +L    E +  L K V    M+VQ         LP+   G    Q    YV+   +
Sbjct: 206  SRAVSLFFVGEQEIHLAKEVTHGGMRVQ---------LPH-VMGSARLQQLAGYVIVRHQ 255

Query: 2054 LGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV 2113
                ++++G S             T G CG       DD +  SG++  +       W  
Sbjct: 256  SAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE 315

Query: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHY 2173
              P++P  P +SS  + P +    G     ++       C+ +    F  CHA V P  +
Sbjct: 316  QAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQ------CEALLRPPFDACHAYVSPLPF 369

Query: 2174 YDACVFDSCFMPGS-SLECASLQAYAALCAQQNICLD-WRNHTHGACLVECP----SHRE 2227
              +C  D C   G  +  C +L  YA  CAQ    L  WR      C V C     ++ E
Sbjct: 370  TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLR-QCTVHCKEKAFTYNE 428

Query: 2228 YQACGPAEEPTCKSSSSQQNNTV-LVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 2286
              AC PA   +C   +S  ++ +  V+GC+CP G         +  +  GCV P   P E
Sbjct: 429  CIACCPA---SCHPRASCVDSEIACVDGCYCPNG---------LIFEDGGCVAPAECPCE 476

Query: 2287 F-------GEHFEFDCKNCVCLEGG---SGIICQPKRCS 2315
            F       G   + DC  C C  G    S  +C P  CS
Sbjct: 477  FHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC-PAECS 514



 Score =  109 bits (273), Expect = 3e-23
 Identities = 91/329 (27%), Positives = 145/329 (44%), Gaps = 32/329 (9%)

Query: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGP-GQAEAPAGVESIL 95
           CS  G+ H+ TFDG  + FP  C Y  A     S   F V L+  P G  +  A V+S+ 
Sbjct: 513 CSVTGDIHFTTFDGRRYTFPATCQYILAKS--RSSGTFTVTLQNAPCGLNQDGACVQSVS 570

Query: 96  LTIKDD-----TIYLTRHLAVLNGAVVSTPHYSPGLLIEK-SDAYTKVYSRAGLTLMWNR 149
           + +  D     T+     + + +   +  P+      I + S  + +V +  G+ ++++R
Sbjct: 571 VILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630

Query: 150 ED-ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSD-GVLFS-PLEFGNMQKINQ--PDV 204
           E   L L++D ++   T GLCG +NG  +  +FLS  GV  S P  FGN  K       +
Sbjct: 631 EGLRLYLQVDQRWVEDTVGLCGTFNG-NTQDDFLSPVGVPESTPQLFGNSWKTLSACSPL 689

Query: 205 VCEDPEEEV-APASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
           V   P +        + +  +   +LT E FA C   +   PY   C++D CRC  G  C
Sbjct: 690 VSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRC--GQPC 747

Query: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323
           +C+T+A ++  C    G P ++R    A  P  + +C  +  Y    +PC  TC  L   
Sbjct: 748 LCATLAHYAHLC-RRHGLPVDFR----ARLPACALSCEASKEYSPCVAPCGRTCQDLASP 802

Query: 324 SLC---------EEHRMDGCFCPEGAQAD 343
             C          +  ++GC CP     D
Sbjct: 803 EACGVDGGDDLSRDECVEGCACPPDTYLD 831



 Score = 96.7 bits (239), Expect = 3e-19
 Identities = 152/720 (21%), Positives = 241/720 (33%), Gaps = 105/720 (14%)

Query: 1031 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1090
            CEW Y+ C +  F+TCR      S   V     C P CP  + + +E  ++CV  + C  
Sbjct: 1408 CEWRYDACASPCFQTCRDPRAA-SCRDVPRGRSCVPVCPTPQ-VLDEVTQRCVYLEDC-- 1463

Query: 1091 YVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1150
                    P   VPTE      +  +        EE + L+Q       +     P   +
Sbjct: 1464 ------VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQ-LSQESPRTPTHRPALTPAAPL 1516

Query: 1151 EKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSS----------TVLSTTP 1200
                N     T    ++   T T    P   T +     PT S            +  TP
Sbjct: 1517 TTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1576

Query: 1201 KLCCLWSDWINEDHPSSGSDDGDRETFDGV---CGAPE-DIECRSVKDPHLSLEQLGQKV 1256
            +   L    +    P+ G   G  ET        G+P   +  RS   P           
Sbjct: 1577 ESSSL---PVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSRSPPAPRFP-------- 1625

Query: 1257 QLVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPI 1316
                     L+ K    +  G +P+                 + T    + T +P+  P+
Sbjct: 1626 ---------LMTKAVTVRGHGSLPV-----------------RTTPPQPSLTASPSSRPV 1659

Query: 1317 TTTTTVTPTPTPTSTQSTTPTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1373
             +   ++ +PT + +     TP  T   + T  P PT   + +  +TP+T   T      
Sbjct: 1660 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQSASSPSTPLTVAGT------ 1713

Query: 1374 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTT-TPIT 1432
                Q P  +P+ T +      T  G +   S P+ +  +  P P P+    P   T + 
Sbjct: 1714 -AAEQVP-VSPLATRSLEIVLSTEKG-EAGHSQPMGSPASPQPHPLPSAPPRPAQHTTMA 1770

Query: 1433 TTTTVTPTPTP------TGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPT 1486
            T +   P  TP      T T     T   +  +  P+   +G    T+ P+    T  P 
Sbjct: 1771 TRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAP- 1829

Query: 1487 PTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPI 1546
                   TP P A   TT + P          T+ P  T + V P      TQ   PT I
Sbjct: 1830 -----VATPGPKASVITTPLQP--------QATTLPAQTLSPVLPFTPAAMTQAHPPTHI 1876

Query: 1547 STTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP 1604
            +     T      G   PT+   P+   T    +  P  + T    +++   ++ PT   
Sbjct: 1877 APPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSL-PTSMY 1935

Query: 1605 TSTKS--TTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTS 1662
             S +   T +TP T+         P G Q  T +P+ T+  ++     T           
Sbjct: 1936 GSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDS--MLVL 1993

Query: 1663 TAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST---LPPAIEMTSTAPPSTPTAP 1719
               +AE   ++  P  +      +T+ P   S   LS    L  A+  T+ A  ST   P
Sbjct: 1994 LPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSIVEGLAEALATTTEANTSTTCVP 2053



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 78/317 (24%), Positives = 124/317 (39%), Gaps = 18/317 (5%)

Query: 35  NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
           ++C  WG  H +TFDG  +   G   Y          + F++ +   P    +P      
Sbjct: 149 SICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRA 208

Query: 95  --LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152
             L  + +  I+L + +    G  V  PH      +++   Y  V  ++  TL W+   A
Sbjct: 209 VSLFFVGEQEIHLAKEVTH-GGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASA 267

Query: 153 LMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNM---QKINQP-----D 203
           + +++  +    T GLCG+ N         S G L   + EF +    Q  NQP      
Sbjct: 268 VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTS 327

Query: 204 VVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTC 263
            +   P  +  P +      +CE LL    F  C   V   P+  +C  D C+  G    
Sbjct: 328 SLPRPPCLQQNPGTMQGVYEQCEALLRPP-FDACHAYVSPLPFTASCTSDLCQSMGDVAT 386

Query: 264 VCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVS 323
            C  +AE++R C+ AG     WRT     +    +       Y E  + C  +C H   S
Sbjct: 387 WCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKA---FTYNECIACCPASC-HPRAS 442

Query: 324 SLCEEHR-MDGCFCPEG 339
            +  E   +DGC+CP G
Sbjct: 443 CVDSEIACVDGCYCPNG 459



 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 70/313 (22%), Positives = 118/313 (37%), Gaps = 46/313 (14%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C    C   CT +GD HY TFDGL + + G C   LV+  S S  +F V ++N +C  + 
Sbjct: 976  CTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVK--STSDVSFSVIVENVNCYSSG 1033

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
             + C + + +      ++       P       ++Q V           ++ G   +V  
Sbjct: 1034 MI-CRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEV---------HTWRVGFFTLVHF 1083

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 2111
            P+  + + ++  +        ++     G CG     T ++   P    ++N +     W
Sbjct: 1084 PQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSW 1143

Query: 2112 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL--------CQLIKDSLFAQ 2163
               +     CP +                  P   C  +PL        C ++   +F  
Sbjct: 1144 AAVE-----CPDTLD----------------PRDMCVLNPLREPFAKKECSILLSEVFEI 1182

Query: 2164 CHALVPPQHYYDACVFDSC-FMPGSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLV 2220
            CH +V    +Y  C+ D+C    G   EC  AS+ AYA  C Q  + +DWR  T   C  
Sbjct: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWR--TPRLCPY 1240

Query: 2221 ECPSHREYQACGP 2233
            +C    +    GP
Sbjct: 1241 DCDFFNKVLGKGP 1253



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 89/398 (22%), Positives = 145/398 (36%), Gaps = 67/398 (16%)

Query: 752  CTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY----------CGQNSSLGS- 800
            C    C   CSI+    ++TFDG +        Y+  Q            C ++++LG  
Sbjct: 2102 CPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDC-KSANLGHL 2160

Query: 801  ----FSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVG 856
                F ++  N+    T +     I  F  +  + L+     V +        +   + G
Sbjct: 2161 NWPPFCLVMLNM----THLAHQVTIDRFNRKVTVDLQPVWPPVSR------YGFRIEDTG 2210

Query: 857  QYLVVESSTGIIVIW-DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSE 915
               ++ + + I + W      + ++ + + K    GLCG  D  + ND T +D  VV   
Sbjct: 2211 HMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGA 2270

Query: 916  LD---FGNSWKEAPTCPDVSTN---PEPCSLNPHRRSWAEKQCS----ILKSSVFSICHS 965
             D   F +SW+   +   V      P+ C         A   CS    ++ +  FS CH 
Sbjct: 2271 EDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------ATTDCSPCLRMVSNRTFSACHR 2321

Query: 966  KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYY 1025
             V P+ F E  + D+            C A+  Y   C K   C+ WR  D CP  C   
Sbjct: 2322 FVPPESFCELWIRDTKYVQQP------CVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSD 2375

Query: 1026 NPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYL----EGCYPRCPKDRPIYEEDLKK 1081
            +    C    EP      +TC+  +GI   +   +     EGC   C +   ++      
Sbjct: 2376 STYQACVTACEPP-----KTCQ--DGILGPLDPEHCQVLGEGCV--CSEGTILHRRHSAL 2426

Query: 1082 CVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQ 1119
            C+   KC C   D+   P A   T  +  S  C +  Q
Sbjct: 2427 CIPEAKCAC--TDSMGVPRALGETWNSSLSGCCQHQCQ 2462



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 66/274 (24%), Positives = 120/274 (43%), Gaps = 43/274 (15%)

Query: 35   NVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
            + C+ +G+ HY+TFDG  F F G C                VHL +          VE++
Sbjct: 983  STCTAYGDRHYRTFDGLPFDFVGACK---------------VHLVKSTSDVSFSVIVENV 1027

Query: 95   ------LLTIKDDTIYLTRHLAVLNGAVVSTPHYSP-GLLIEKSDAYT--------KVYS 139
                  ++  K  +I +   L V +     + + SP   L +K + +T          + 
Sbjct: 1028 NCYSSGMICRKFISINVGNSLIVFDD---DSGNPSPESFLDDKQEVHTWRVGFFTLVHFP 1084

Query: 140  RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDG--VLFSPLEFGNM- 196
            +  +TL+W++   + ++   +++    GLCG+++ L++ +E  +     L +P EFG+  
Sbjct: 1085 QEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFD-LKTINEMRTPENLELTNPQEFGSSW 1143

Query: 197  QKINQPDVVCEDPEEEVAPASCSEHRAECE-RLLTAEAFADCQDLVPLEPYLRACQQDRC 255
              +  PD +  DP +        E  A+ E  +L +E F  C  +V +  +   C  D C
Sbjct: 1144 AAVECPDTL--DPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTC 1201

Query: 256  RCPGGD--TCVCSTVAEFSRQCSHAGGRPGNWRT 287
             C  G    C C++V+ ++ QC   G    +WRT
Sbjct: 1202 GCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRT 1234



 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 59/226 (26%), Positives = 84/226 (37%), Gaps = 39/226 (17%)

Query: 413  LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATG---AGFANTWKAQSSCHD--K 467
            + V   + S+ Q  GLCG  +G   +D     G V       A F ++W+  SS     +
Sbjct: 2232 MIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQ 2291

Query: 468  LDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNED 527
              +  D C+    S       C  +    T F  CH  V P  + +    DT   Q    
Sbjct: 2292 TRFRPDSCATTDCSP------CLRMVSNRT-FSACHRFVPPESFCELWIRDTKYVQQP-- 2342

Query: 528  CLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADS 587
              C AL+ Y   C    V +  WR          CP    FL +  +  Q C +  E   
Sbjct: 2343 --CVALTVYVAMCHKFHVCI-EWRRS------DYCP----FLCSSDSTYQACVTACEPPK 2389

Query: 588  HCLEGF-APVD---------GCGCPDHTFLDEK--GRCVPLAKCSC 621
             C +G   P+D         GC C + T L  +    C+P AKC+C
Sbjct: 2390 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCAC 2435


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score =  410 bits (1054), Expect = e-114
 Identities = 285/947 (30%), Positives = 427/947 (45%), Gaps = 113/947 (11%)

Query: 225  CERLLTA-EAFADCQDLVPL------EPYLRACQQD---RCRCPGG---DTCVCSTVAE- 270
            CERL    + ++DC  L P       +    +C+++    C CP G   +  +C   A  
Sbjct: 465  CERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHC 524

Query: 271  ---FSRQ-----------CSHAGGRPGNWRTATSAVSP--------GASKTCPGNLVYLE 308
               + RQ           C+    R G W  A  A+ P        G   T  G      
Sbjct: 525  PCYYCRQRYVPGDTVRQLCNPCVCRDGRWHCA-QALCPAECAVGGDGHYLTFDGRSYSFW 583

Query: 309  SGSPCMDTCSHLEVSS----LCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSD 364
             G  C  +     V      L E    D   C       L  T + L D           
Sbjct: 584  GGQGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLRDS---------- 633

Query: 365  GSVLLNELQVNLPHVTAS-FSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQG 423
            G+VL+N   V LP + A   SV R SS  +++       L     PV   ++TLD     
Sbjct: 634  GAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVA--YITLDPRHAH 691

Query: 424  QVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKA--QSSCHDKLDWLDDPCSLNIES 481
            QVQGLCG F   + DDF T +G VE + A FA+ ++   +  C  +   L  PC+ + + 
Sbjct: 692  QVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQR 751

Query: 482  ANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACT 541
              +AE  C++L  +   F  CH  VD   +Y RC    C C    DCLC  LS+YAR C 
Sbjct: 752  HAFAEAACAILHSSV--FQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCA 809

Query: 542  AKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGC 601
             +G       + +C      CP  Q +      C Q C    +    C E  + V GC C
Sbjct: 810  QEGASPPWRNQTLCPV---MCPGGQEYRECAPACGQHCGKPED----CGELGSCVAGCNC 862

Query: 602  PDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCT 661
            P     D +G+CVP + C C         G   +++  RC+C++  L     R       
Sbjct: 863  PLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAF 922

Query: 662  APKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDG--LMDDGRGGCVVEK 719
             P+  +       L    P A    +  AG        GCVCP G  L+D+    CV   
Sbjct: 923  CPRELVYAPGACLLTCDSPSAN--HSCPAG-----STDGCVCPPGTVLLDER---CVPPD 972

Query: 720  ECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDF 779
             CPC H+   Y   A I+ DCN C C+  +W CT     G C   G+ HY+TFDG  + +
Sbjct: 973  LCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTY 1032

Query: 780  DGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVV 839
             G C Y+ V++      + G F++  +N+PCG +G+TC+KA+ + +  T + +     V 
Sbjct: 1033 PGACEYLLVRE------ASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVT 1086

Query: 840  IQRDEGHHVA----YT-----TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVC 890
            +    G  V     YT      R  G +L++ +  G+ ++WD  T V ++L+P ++G V 
Sbjct: 1087 VN---GVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVA 1143

Query: 891  GLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEK 950
            GLCG+FD  ++ND  +R  ++  +     +SW+ +P CP+    P PC++N HR  WA  
Sbjct: 1144 GLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARA 1203

Query: 951  QCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV 1010
            +C  L   +F++CH++V P+  YE C++D+C CD+GGDCEC CSA+A+YA EC + G  V
Sbjct: 1204 RCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHV 1263

Query: 1011 FWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTIN---GIHSNISVSYLEGCYPR 1067
             WR+ +LC + C       E    YE CG     TC   +   G H  + V+ +EGC+  
Sbjct: 1264 RWRSQELCSLQC-------EGGQVYEACGPTCPPTCHEQHPEPGWHCQV-VACVEGCF-- 1313

Query: 1068 CPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVC 1114
            CP+   ++      C+    C C      +PPG+ +  ++ C +C C
Sbjct: 1314 CPEGTLLHG---GACLEPASCPCEWGRNSFPPGSVL--QKDCGNCTC 1355



 Score =  160 bits (404), Expect = 2e-38
 Identities = 179/705 (25%), Positives = 256/705 (36%), Gaps = 148/705 (20%)

Query: 1796 CVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPT---------P 1846
            C L    YAPG                C+     E   W+C +   P+           P
Sbjct: 882  CQLGARRYAPGSATMK----------ECNRCICQERGLWNCTARHCPSQAFCPRELVYAP 931

Query: 1847 SKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNTVEIVKV 1906
                 T   PS+  S P   T    CP                          TV ++  
Sbjct: 932  GACLLTCDSPSANHSCPAGSTDGCVCPP------------------------GTV-LLDE 966

Query: 1907 ECEPPPMPTCSNG----LQPVRVEDPDGCCW----HWECDCY-----CTGWGDPHYVTFD 1953
             C PP +  C +     L    +++    C      W C        C   G PHYVTFD
Sbjct: 967  RCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFD 1026

Query: 1954 GLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTV 2013
            GL ++Y G C Y+LV E S     F V   N  C  +  ++C + L VR E        V
Sbjct: 1027 GLAFTYPGACEYLLVREAS---GLFTVSAQNLPCGASG-LTCTKALAVRLEG-----TVV 1077

Query: 2014 HMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRLPY 2071
            HM+  +  V VN  +V  P  Y   GL + ++G+ +++    LG+ + ++G +  +    
Sbjct: 1078 HMLRGRA-VTVNGVSVTPPKVYTGPGLSLRRAGL-FLLLSTHLGLTLLWDGGTRVLVQLS 1135

Query: 2072 HRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRP 2131
             +F     G CG      S+D     G +    E AA  W ++    P CP         
Sbjct: 1136 PQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLS----PLCPEPGD----- 1186

Query: 2132 AVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFM-PGSSLE 2190
               +P       H+       C  +   LF  CHA VPPQ +Y+ C++D+C    G   E
Sbjct: 1187 ---LPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCE 1243

Query: 2191 --CASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQ-- 2246
              C+++  YA  CA+    + WR+     C ++C   + Y+ACGP   PTC     +   
Sbjct: 1244 CLCSAIATYADECARHGHHVRWRSQE--LCSLQCEGGQVYEACGPTCPPTCHEQHPEPGW 1301

Query: 2247 --NNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEH-------FEFDCKN 2297
                   VEGCFCPEGT+ +            C+ P + P E+G +        + DC N
Sbjct: 1302 HCQVVACVEGCFCPEGTLLHGG---------ACLEPASCPCEWGRNSFPPGSVLQKDCGN 1352

Query: 2298 CVCLE-----GGSGIICQP--KRCSQKPVT-----HCVEDGTYLATEVNPADTCCNITVC 2345
            C C E     GG G  C+     C++         HCV  G            C N   C
Sbjct: 1353 CTCQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGW----------LCDNQDDC 1402

Query: 2346 KCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPF-YWCESKGVCVHGNAEYQPGSPVYSSKC 2404
               +    E+    P   E +     G C P    C+ +  C  G  E     P     C
Sbjct: 1403 GDGSD---EEGCAAPGCGEGQMTCSSGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLAC 1459

Query: 2405 QD--CV-----------CTDKVDNNTLLNVIACTHVPCNTSCSPG 2436
             D  C+           C D  D  + L  + C  VP   SC  G
Sbjct: 1460 ADGRCLPPALLCDGHPDCLDAADEESCLGQVTC--VPGEVSCVDG 1502



 Score =  137 bits (346), Expect = 1e-31
 Identities = 139/492 (28%), Positives = 195/492 (39%), Gaps = 61/492 (12%)

Query: 1933 WHWE---CDCYCTGWGDPHYVTFDGLYYSYQGN--CTYVLVEEISPSVDNFGVYIDNYHC 1987
            WH     C   C   GD HY+TFDG  YS+ G   C Y LV++         + +++  C
Sbjct: 553  WHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKG--QLLILLEHGAC 610

Query: 1988 DPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPY-KKYGLEVYQSGIN 2046
            D     SC   + V  E   + ++          V VN Q V LP+    GL V ++   
Sbjct: 611  DAG---SCLHAISVSLEDTHIQLRD------SGAVLVNGQDVGLPWIGAEGLSVRRASSA 661

Query: 2047 YVVDIPELGVLVSYNGLSFSVRL----PYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVS 2102
            +++ +   G  V + GLS  V      P H   +  +G CGT T    DD + P+G++ +
Sbjct: 662  FLL-LRWPGAQVLW-GLSDPVAYITLDPRH--AHQVQGLCGTFTQNQQDDFLTPAGDVET 717

Query: 2103 NCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFA 2162
            +  A A ++ V    K  CP   S    P  T          +       C ++  S+F 
Sbjct: 718  SIAAFASKFQV--AGKGRCPSEDSALLSPCTT-------HSQRHAFAEAACAILHSSVFQ 768

Query: 2163 QCHALVPPQHYYDACVFDSCFM-PGSSLECASLQAYAALCAQQNICLDWRNHTHGACLVE 2221
            +CH LV  + +Y  C+   C   PGS   C  L AYA  CAQ+     WRN T   C V 
Sbjct: 769  ECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQT--LCPVM 826

Query: 2222 CPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGC-VGP 2280
            CP  +EY+ C PA    C            V GC CP G +    G  V    C C +G 
Sbjct: 827  CPGGQEYRECAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGA 886

Query: 2281 DNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQK---PVTHCVEDGTYLATEVNPAD 2337
                   G     +C  C+C E G    C  + C  +   P       G  L T  +P+ 
Sbjct: 887  RRYAP--GSATMKECNRCICQERGLW-NCTARHCPSQAFCPRELVYAPGACLLTCDSPS- 942

Query: 2338 TCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGS 2397
               N +    +T  C     VCP G    + ++  RC P   C     C H    Y P +
Sbjct: 943  --ANHSCPAGSTDGC-----VCPPG----TVLLDERCVPPDLCP----CRHSGQWYLPNA 987

Query: 2398 PVYSSKCQDCVC 2409
             +    C  CVC
Sbjct: 988  TI-QEDCNVCVC 998



 Score =  130 bits (327), Expect = 2e-29
 Identities = 94/315 (29%), Positives = 143/315 (45%), Gaps = 23/315 (7%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILL 96
            C   G  HY TFDG  F +PG C+Y    +  G +   A +L  G   A      +++ +
Sbjct: 1014 CQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCG---ASGLTCTKALAV 1070

Query: 97   TIKDDTIYLTRHLAV-LNGAVVSTP--HYSPGLLIEKSDAYTKVYSRAGLTLMWNREDAL 153
             ++   +++ R  AV +NG  V+ P  +  PGL + ++  +  + +  GLTL+W+    +
Sbjct: 1071 RLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRV 1130

Query: 154  MLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEV 213
            +++L  +FR    GLCGD++G  S       GVL    E         P  +C +P +  
Sbjct: 1131 LVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSP--LCPEPGDLP 1188

Query: 214  APASCSEHRAECER----LLTAEAFADCQDLVPLEPYLRACQQDRCRC-PGGD-TCVCST 267
             P + + HRA   R     L    F  C   VP + +   C  D C C  GGD  C+CS 
Sbjct: 1189 HPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSA 1248

Query: 268  VAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTC--SHLEVSSL 325
            +A ++ +C+  G     WR+         S  C G  VY   G  C  TC   H E    
Sbjct: 1249 IATYADECARHGHHV-RWRSQEL-----CSLQCEGGQVYEACGPTCPPTCHEQHPEPGWH 1302

Query: 326  CEEHR-MDGCFCPEG 339
            C+    ++GCFCPEG
Sbjct: 1303 CQVVACVEGCFCPEG 1317



 Score =  129 bits (325), Expect = 3e-29
 Identities = 84/272 (30%), Positives = 130/272 (47%), Gaps = 27/272 (9%)

Query: 400 GVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWK 459
           G+ + V+L     + +++D    GQ QGLCG +NG   DDF    G +    A F N+W+
Sbjct: 294 GLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWR 353

Query: 460 ---AQSSCHDKLDWLD--DPCSL---NIESANY---AEHWCSLLKKTETPFGRCHSAVDP 508
              ++S C D ++     DP  L   ++E  +    A+  C  L   E PFG+CH+ V P
Sbjct: 354 LPGSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQL--LEGPFGQCHAQVSP 411

Query: 509 AEYYKRCKYDTC-------NCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGS 561
           AEY++ C +  C         +  +  +CA  +SY +AC  + + +   +   C +    
Sbjct: 412 AEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCER---L 468

Query: 562 CPNSQVFLYNLTTCQQTCRSLSEADSH-CLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCS 620
           CP  Q++   ++ C  +C ++ + +   C E    V GC CP   F +    CVP A C 
Sbjct: 469 CPGGQLYSDCVSLCPPSCEAVGQGEEESCRE--ECVSGCECPRGLFWNGT-LCVPAAHCP 525

Query: 621 CYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQ 652
           CY+       GD V +    CVCRDGR HC Q
Sbjct: 526 CYYCRQRYVPGDTVRQLCNPCVCRDGRWHCAQ 557



 Score =  113 bits (283), Expect = 2e-24
 Identities = 100/399 (25%), Positives = 156/399 (39%), Gaps = 62/399 (15%)

Query: 760  TCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSK 819
            TC+ +   HY TFDG++Y F G C+Y+      G   S  +  +        T G  C +
Sbjct: 194  TCASWSGFHYRTFDGRHYHFLGRCTYLLA----GAADSTWAVHL--------TPGDRCPQ 241

Query: 820  ---AIKIFMGRTELKLED-----KHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIW 871
                 ++ MG  E+ ++      K ++V +         + + +G +LV+    G++V  
Sbjct: 242  PGHCQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRL 301

Query: 872  DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK---EAPTC 928
            D+  ++ I +     G   GLCG ++    +DF      +      FGNSW+       C
Sbjct: 302  DRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGC 361

Query: 929  PDVSTNPEPC--------SLNP-HRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHD 979
             D     + C         + P H R+ A+  C  L    F  CH++V P  ++EAC+  
Sbjct: 362  LDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFA 421

Query: 980  SCSCDTGGD-----CECFCSAVASYAQECTKEGACVFWRTPDLCPIFCD----YYNPPHE 1030
             C+    G       +  C+  ASY Q C +    + WR P  C   C     Y +    
Sbjct: 422  YCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSL 481

Query: 1031 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1090
            C    E  G    E+CR              E C   C   R ++      CV A  C C
Sbjct: 482  CPPSCEAVGQGEEESCR--------------EECVSGCECPRGLFWNG-TLCVPAAHCPC 526

Query: 1091 YVEDTHYPPGASVPTEETCKSCVCTNS----SQVVCRPE 1125
            Y     Y PG +V   + C  CVC +     +Q +C  E
Sbjct: 527  YYCRQRYVPGDTV--RQLCNPCVCRDGRWHCAQALCPAE 563



 Score =  102 bits (253), Expect = 7e-21
 Identities = 105/397 (26%), Positives = 157/397 (39%), Gaps = 60/397 (15%)

Query: 1934 HWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKV 1993
            H      C  W   HY TFDG +Y + G CTY+L    + + D+        H  P D+ 
Sbjct: 188  HQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLL----AGAADSTWA----VHLTPGDR- 238

Query: 1994 SCPRTLIVRHET---QEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVD 2050
             CP+    +  T   +EVLI+  +     V V+         +  +GL +   G +++V 
Sbjct: 239  -CPQPGHCQRVTMGPEEVLIQAGN-----VSVKGQLVPEGQSWLLHGLSLQWLG-DWLVL 291

Query: 2051 IPELGVLVSYN---GLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAA 2107
               LGV+V  +    +S SV    H     T+G CG       DD + P G +       
Sbjct: 292  SGGLGVVVRLDRTGSISISVD---HELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATF 348

Query: 2108 ADQWLVNDPSKPHCPHSSSTTKR-------PAVTVPGGGKTTPHKDCTPSPLCQLIKDSL 2160
             + W +   S+  C  +    +         A   PG      H       +C  + +  
Sbjct: 349  GNSWRL-PGSESGCLDAVEVAQGCDPLGLIDADVEPG------HLRAEAQDVCHQLLEGP 401

Query: 2161 FAQCHALVPPQHYYDACVFDSC--FMPGSSLE------CASLQAYAALCAQQNICLDWRN 2212
            F QCHA V P  Y++AC+F  C   M GS  E      CA+  +Y   CA+++I + WR 
Sbjct: 402  FGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRK 461

Query: 2213 HTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV---LVEGCFCPEGTMNYAPGFD 2269
               G C   CP  + Y  C     P+C++    +  +     V GC CP G         
Sbjct: 462  --PGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNG---T 516

Query: 2270 VCVKTCGCVGPDNVPREF---GEHFEFDCKNCVCLEG 2303
            +CV    C  P    R+    G+     C  CVC +G
Sbjct: 517  LCVPAAHC--PCYYCRQRYVPGDTVRQLCNPCVCRDG 551



 Score = 86.7 bits (213), Expect = 3e-16
 Identities = 83/317 (26%), Positives = 132/317 (41%), Gaps = 29/317 (9%)

Query: 37  CSTWGNFHYKTFDGDVFRFPG--LCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESI 94
           C+  G+ HY TFDG  + F G   C Y+   D    Y +  + +    G  +A + + +I
Sbjct: 564 CAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQD----YVKGQLLILLEHGACDAGSCLHAI 619

Query: 95  LLTIKDDTIYLTRHLAVL-NGAVVSTPHY-SPGLLIEKSDAYTKVYSRAGLTLMWNREDA 152
            ++++D  I L    AVL NG  V  P   + GL + ++ +   +    G  ++W   D 
Sbjct: 620 SVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDP 679

Query: 153 L-MLELDTKFRNHTCGLCGDYNGLQSYSEFLSDG--VLFSPLEFGNMQKINQPDVVCEDP 209
           +  + LD +  +   GLCG +   Q   +FL+    V  S   F +  ++        + 
Sbjct: 680 VAYITLDPRHAHQVQGLCGTFTQNQQ-DDFLTPAGDVETSIAAFASKFQVAGKGRCPSED 738

Query: 210 EEEVAPASCSEHR-----AECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCV 264
              ++P +    R     A C  +L +  F +C  LV  EP+   C    C C  G  C+
Sbjct: 739 SALLSPCTTHSQRHAFAEAAC-AILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCL 797

Query: 265 CSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVSS 324
           C  ++ ++R+C+  G  P  WR  T          CPG   Y E    C   C   E   
Sbjct: 798 CPVLSAYARRCAQEGASP-PWRNQTL-----CPVMCPGGQEYRECAPACGQHCGKPED-- 849

Query: 325 LCEE--HRMDGCFCPEG 339
            C E    + GC CP G
Sbjct: 850 -CGELGSCVAGCNCPLG 865



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 83/333 (24%), Positives = 128/333 (38%), Gaps = 47/333 (14%)

Query: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILL 96
           C++W  FHY+TFDG  + F G C Y  A     ++   AVHL  G      P       +
Sbjct: 195 CASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTW---AVHLTPGD---RCPQPGHCQRV 248

Query: 97  TIKDDTIYLTRHLAVLNGAVV--STPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALM 154
           T+  + + +      + G +V         GL ++    +  +    G+ +  +R  ++ 
Sbjct: 249 TMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSIS 308

Query: 155 LELDTKFRNHTCGLCGDYNGLQSYSEFL--SDGVLFSPLEFGNMQKINQPDVVCEDPEE- 211
           + +D +    T GLCG YNG     +F+    G+      FGN  ++   +  C D  E 
Sbjct: 309 ISVDHELWGQTQGLCGLYNGWPE-DDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEV 367

Query: 212 ------------EVAPASC-SEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCR-- 256
                       +V P    +E +  C +LL    F  C   V    Y  AC    C   
Sbjct: 368 AQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEG-PFGQCHAQVSPAEYHEACLFAYCAGA 426

Query: 257 -----CPGGDTCVCSTVAEFSRQCS--HAGGRPGNWRTATSAVSPG-ASKTCPGNLVYLE 308
                  G    VC+T A + + C+  H   R   WR       PG   + CPG  +Y +
Sbjct: 427 MAGSGQEGRQQAVCATFASYVQACARRHIHIR---WR------KPGFCERLCPGGQLYSD 477

Query: 309 SGSPCMDTCSHL--EVSSLCEEHRMDGCFCPEG 339
             S C  +C  +       C E  + GC CP G
Sbjct: 478 CVSLCPPSCEAVGQGEEESCREECVSGCECPRG 510



 Score = 79.3 bits (194), Expect = 5e-14
 Identities = 65/228 (28%), Positives = 77/228 (33%), Gaps = 47/228 (20%)

Query: 562  CPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSC 621
            CP  QV     T+C   C  L        E   P  GCGCP    L   G CVP   C C
Sbjct: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQP--GCGCPGGQLL-HNGTCVPPTACPC 4874

Query: 622  YHRGL-------------YLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPK---- 664
                L              L  G V+ R   RCVC  G   C  +      C  P     
Sbjct: 4875 TQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLV-----DCQVPPGETW 4929

Query: 665  ----------IHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGG 714
                          C  + A  T      +C +  A        SGCVC  G      G 
Sbjct: 4930 QQVAPGELGLCEQTCLEMNATKTQS----NCSSARA--------SGCVCQPGHFRSQAGP 4977

Query: 715  CVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCS 762
            CV E  C C H    +  G++ +  C +C C  GR VCTQ     TC+
Sbjct: 4978 CVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025



 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 40/159 (25%), Positives = 58/159 (36%), Gaps = 31/159 (19%)

Query: 597  DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLI 656
            D CGC      D  G C    +C C            +    + C      +  R   L 
Sbjct: 1232 DACGC------DSGGDC----ECLC----------SAIATYADECARHGHHVRWRSQELC 1271

Query: 657  GQSCTAPKIHMDCSNL---TALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRG 713
               C   +++  C      T           CQ +A       CV GC CP+G +  G G
Sbjct: 1272 SLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVA-------CVEGCFCPEGTLLHG-G 1323

Query: 714  GCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVC 752
             C+    CPC    + +  G+ ++ DC  CTC+ G+W C
Sbjct: 1324 ACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362



 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 53/194 (27%), Positives = 73/194 (37%), Gaps = 26/194 (13%)

Query: 582  LSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCV-----PLAKCSC----YHRGLYLEAGD 632
            +++AD  C   F  +D  GC      +E   CV        +CSC      R  +     
Sbjct: 4338 MAKADPTCNSTFLHLDTQGCYSGPCPEE---CVWSSWSSWTRCSCRVLVQQRYRHQGPAS 4394

Query: 633  VVVRQEERCVCRDGRLH-CRQIRLIGQSCTAP-KIHMDCSNLTALATSKPRALSCQTLAA 690
               R    C   DG    C        SCT P + H   S    L  +      CQ L  
Sbjct: 4395 RGARAGAPCTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPP 4454

Query: 691  GYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDL-----YSSGAKIKVDCNTCTC 745
                  C  GC CP GL++   GGC+  +EC C H +        + G ++++ C  C C
Sbjct: 4455 ------CQPGCYCPKGLLEQA-GGCIPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECEC 4507

Query: 746  KRGRWVCTQAVCHG 759
            +RG   CT   C G
Sbjct: 4508 RRGELHCTSQGCQG 4521



 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 27/66 (40%), Positives = 34/66 (51%), Gaps = 2/66 (3%)

Query: 697  CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD-CNTCTCKRGRWVCTQA 755
            C  GC CP GL       C+   +CPC  +  LY+SGA  ++D CN CTC  G+  CT  
Sbjct: 2922 CAPGCTCPPGLFLHN-ASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSE 2980

Query: 756  VCHGTC 761
             C   C
Sbjct: 2981 RCPVAC 2986



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 100/457 (21%), Positives = 151/457 (33%), Gaps = 119/457 (26%)

Query: 2254 GCFCPEGTMNYAPGFDVCVKTCGCVGPD-NVPREFG--EHFEFDCKNCVCLEG------- 2303
            GC CP G +    G  V + +C C  P  N   E    +  + DC+NC C+         
Sbjct: 4703 GCRCPPGQL-VQDGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQ 4761

Query: 2304 ------------------GSGIICQPKRCSQKP-VTHCVEDGTYLATEVN--PADTCCNI 2342
                              G G + + + C   P V  C    T    E N  P   C   
Sbjct: 4762 ECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPG 4821

Query: 2343 TVCKCNTSLCKEKPSVC----PLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA------- 2391
             V     + C   P +C    P    V+    PG  CP       G CV   A       
Sbjct: 4822 QVLSACATSC---PCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHS 4878

Query: 2392 --------------EYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGF 2437
                          E  PG+ V +  C  CVC             +C+ V C       +
Sbjct: 4879 LPWGLTLTLEEQAQELPPGT-VLTRNCTRCVCHG--------GAFSCSLVDCQVPPGETW 4929

Query: 2438 ELMEAPGE---CCKKC-------EQTHCIIKRPDNQHVILKPGDFKSD-----PKNNCTF 2482
            + + APGE   C + C        Q++C   R      + +PG F+S      P+++C  
Sbjct: 4930 QQV-APGELGLCEQTCLEMNATKTQSNCSSARASG--CVCQPGHFRSQAGPCVPEDHCEC 4986

Query: 2483 F-----------------SCVKIHNQLISS--VSNITCPNFDASICIPGSITFMPNGCCK 2523
            +                 SC+ +  + + +   S +TC   +  +  PGS       CC 
Sbjct: 4987 WHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGS-------CCP 5039

Query: 2524 TCTPR--NETRVPCSTVPVTTEVSYAGC-TKTVLMNHCSGSCGTFVMYSAKAQALDHSCS 2580
            +C      E    C  +      +   C    V +++CSG C +      +   L   C 
Sbjct: 5040 SCRREAPEEQSPSCQLLTELRNFTKGTCYLDQVEVSYCSGYCPSSTHVMPEEPYLQSQCD 5099

Query: 2581 CCK---EEKTSQREVVLSCPNGGSLTHTYTHIESCQC 2614
            CC    + ++  R + L C  G +       I SCQC
Sbjct: 5100 CCSYRLDPESPVRILNLRCLGGHTEPVVLPVIHSCQC 5136



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 49/180 (27%), Positives = 63/180 (35%), Gaps = 20/180 (11%)

Query: 577  QTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVR 636
            Q C         C     PVDG          E     P + CS   RG           
Sbjct: 1730 QNCPGPEHQSQACFTAACPVDG----------EWSTWSPWSVCSEPCRGTMTRQRQCHSP 1779

Query: 637  QE--ERCVCRDGRLHC-RQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYY 693
            Q     C    G LH  RQ +   Q       +  CS         P  L+C  ++    
Sbjct: 1780 QNGGRTCAALPGGLHSTRQTKPCPQDGCP---NATCSGELMFQPCAPCPLTCDDISGQVT 1836

Query: 694  ---HTECVS-GCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGR 749
                  C S GC CP+G +    G CV  ++CPC+ +   Y  G +IK DC  C C+ GR
Sbjct: 1837 CPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKADCQLCICQDGR 1896



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 62/271 (22%), Positives = 82/271 (30%), Gaps = 93/271 (34%)

Query: 575  CQQTCRSLSEADSHCLEGFAPVDG-CGCPDHTFLDEKGRCVPLAKCSC-YHRGLY----- 627
            C ++C+ LS   S C  G       CGCP    L + G CVP A C C Y  G       
Sbjct: 3542 CPRSCQDLSPG-SVCQPGSVGCQPTCGCPLGQ-LSQDGLCVPPAHCRCQYQPGAMGIPEN 3599

Query: 628  --------------LEAGDVVVRQEERCVCRDGRLHCRQI-------------------- 653
                          LE G+VV    + C C  G L C+++                    
Sbjct: 3600 QSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSV 3659

Query: 654  ------RLIGQSCTAPKIHMDCSNLTALATSKPRALSCQ--------------------- 686
                  +L  + C  P            +T   R   C                      
Sbjct: 3660 SCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHV 3719

Query: 687  TLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHN-------------------- 726
            T   G +   C  GC CP+G     R  CV  +ECPCV                      
Sbjct: 3720 TQQVGCFSEGCEEGCHCPEGTFQH-RLACV--QECPCVLTAWLLQELGATIGDPGQPLGP 3776

Query: 727  NDLYSSGAKIKVDCNTCTCKRGRWVCTQAVC 757
             D   SG  ++  C  C+C  G+  C+   C
Sbjct: 3777 GDELDSGQTLRTSCGNCSCAHGKLSCSLDDC 3807



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 66/276 (23%), Positives = 94/276 (34%), Gaps = 76/276 (27%)

Query: 550  WREHVCNKDVGSCPNSQ----VFLYNLTT-CQQTCRSLSEADSHCLEGFAPVDGCGCPDH 604
            W +  CN   G CP  +    VF  +    C  +C  L +    CL+G     GC CP  
Sbjct: 4654 WAQESCNG--GPCPECEAQDTVFTLDCANQCPHSCADLWDR-VQCLQGPCR-PGCRCPPG 4709

Query: 605  TFLDEKGRCVPLAKCSC----YHRGLYLEAGDVVVRQEERCVCRDGRLHC--RQIRLIG- 657
              + + GRCVP++ C C     +    L     V    + C C +  L C  ++  ++G 
Sbjct: 4710 QLVQD-GRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGP 4768

Query: 658  ----QSCTAP------KIHMDCSN-------------------------------LTALA 676
                 SC+AP      + H  C                                 L+A A
Sbjct: 4769 WSAWSSCSAPCGGGTMERHRTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACA 4828

Query: 677  TSKPRALSCQTLAAGYYHTE--CVSGCVCPDGLMDDGRGGCVVEKECPCVHNN------- 727
            TS P    C  L  G    +  C  GC CP G +    G CV    CPC  ++       
Sbjct: 4829 TSCP--CLCWHLQPGAICVQEPCQPGCGCPGGQLLH-NGTCVPPTACPCTQHSLPWGLTL 4885

Query: 728  ------DLYSSGAKIKVDCNTCTCKRGRWVCTQAVC 757
                       G  +  +C  C C  G + C+   C
Sbjct: 4886 TLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 59/240 (24%), Positives = 89/240 (37%), Gaps = 38/240 (15%)

Query: 2222 CPSHREYQACGPAEEPTCKSSSSQ----QNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGC 2277
            C     +Q C P    TC   S Q     +      GC+CPEG +  + G+ V  + C C
Sbjct: 1812 CSGELMFQPCAPCPL-TCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPC 1870

Query: 2278 VGPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPAD 2337
            +  D      G+  + DC+ C+C +G      +P+RC   P   C  D  +  +  +P  
Sbjct: 1871 L-VDGARYWPGQRIKADCQLCICQDG------RPRRCRLNP--DCAVDCGW--SSWSPWA 1919

Query: 2338 TCCNITVCKCNTSLCK------EKPSVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNA 2391
             C       C +   +        P     G + +      R C    CE    C H   
Sbjct: 1920 KCLG----PCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPCEG---CEHQGQ 1972

Query: 2392 EYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIA-CTHVPCNTSCSPGFELMEAPGECCKKC 2450
             ++ G   +   C+ C C        L N+ A C+      SC  G+ L+E  GE C  C
Sbjct: 1973 VHRVGERWHGGPCRVCQC--------LHNLTAHCSPYCPLGSCPQGWVLVEGTGESCCHC 2024



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 94/390 (24%), Positives = 125/390 (32%), Gaps = 77/390 (19%)

Query: 2081 QCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHC-------PHSSSTTKRP-- 2131
            Q G C   +S  C LPS    ++ E A  Q +  D     C       PH       P  
Sbjct: 4713 QDGRCVPISSCRCGLPSAN--ASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPWS 4770

Query: 2132 ---AVTVP-GGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGS 2187
               + + P GGG    H+ C   P          A C A    Q     C    C     
Sbjct: 4771 AWSSCSAPCGGGTMERHRTCEGGPGV--------APCQAQDTEQR--QECNLQPC----- 4815

Query: 2188 SLECASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQ- 2246
              EC   Q  +A CA    CL W       C+ E         C    +P C     Q  
Sbjct: 4816 -PECPPGQVLSA-CATSCPCLCWHLQPGAICVQE--------PC----QPGCGCPGGQLL 4861

Query: 2247 NNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSG 2306
            +N   V    CP    +   G  + ++      P       G     +C  CVC   G  
Sbjct: 4862 HNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPP------GTVLTRNCTRCVC--HGGA 4913

Query: 2307 IICQPKRCSQKPVTHCVEDGTYLAT-EVNPADTCC---NITVCKCNTSLCKEKPSVCPLG 2362
              C    C   P     E    +A  E+   +  C   N T  + N S  +    VC  G
Sbjct: 4914 FSCSLVDCQVPPG----ETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPG 4969

Query: 2363 FEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVI 2422
                 +   G C P   CE    C H    + PGS  +   C+ C+C        L    
Sbjct: 4970 H---FRSQAGPCVPEDHCE----CWHLGRPHLPGSE-WQEACESCLC--------LSGRP 5013

Query: 2423 ACTHVPCNTSCSPGFELMEAPGECCKKCEQ 2452
             CT      +C+ G E++  PG CC  C +
Sbjct: 5014 VCTQHCSPLTCAQGEEMVLEPGSCCPSCRR 5043



 Score = 48.9 bits (115), Expect = 7e-05
 Identities = 32/103 (31%), Positives = 43/103 (41%), Gaps = 19/103 (18%)

Query: 660  CTAPKIHMDCSNLTALATSKPRALSCQTLAA--GYYHTECVSGCVCPDGLMDDGRGGCVV 717
            C   K  +DC+   A         SC  L+A  G   T C  GC CP G++      CV 
Sbjct: 3090 CPRDKQWLDCAQGPA---------SCAELSAPRGTNQT-CHPGCHCPSGMLLLNNV-CVP 3138

Query: 718  EKECPCVHNNDLYSSGAKIKVDCNTCTCKRG------RWVCTQ 754
             ++CPC H   LY  G+ +   C  C+C  G       W C +
Sbjct: 3139 TQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAE 3181



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 69/287 (24%), Positives = 103/287 (35%), Gaps = 69/287 (24%)

Query: 500  GRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDV 559
            G C SA    +    C+ D  +     DC+ A  S ++    + G+ L   R+ +    +
Sbjct: 2474 GECLSAERRCDLRPDCQ-DGSDEDGCVDCVLAPWSVWSSCSRSCGLGLTFQRQELLRPPL 2532

Query: 560  --GSCPNSQVFLYNLTTC-QQTCR--------------SLSEADSH------CLEGFAPV 596
              GSCP  +   +   +C  Q C               S+S    H      C++     
Sbjct: 2533 PGGSCPRDR---FRSQSCFVQACPVAGAWAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKN 2589

Query: 597  DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLI 656
             G  CP  +   E+  C  L  CS    G   E G V V  +   +C+ G      +   
Sbjct: 2590 GGAPCPGAS--QERAPC-GLQPCS---GGTDCELGRVYVSAD---LCQKGL-----VPPC 2635

Query: 657  GQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDG-LMDDGRGGC 715
              SC  PK +  CS                          CV GC CP G L+ D R  C
Sbjct: 2636 PPSCLDPKANRSCSG------------------------HCVEGCRCPPGLLLHDTR--C 2669

Query: 716  VVEKECPCVHNNDLYSSGAKIKV-DCNTCTCKRGRWVCTQAVCHGTC 761
            +   ECPC+   +L   G    + +C+ C C++G  +C    C   C
Sbjct: 2670 LPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGGCPLPC 2716



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 46/200 (23%), Positives = 72/200 (36%), Gaps = 15/200 (7%)

Query: 562  CPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSC 621
            CP     +     C + C  L E    C +      GC CP  + L++ G CVP+  C C
Sbjct: 4062 CPAGMEVVTCANRCPRRCSDLQEGIV-CQDDQVCQKGCRCPKGS-LEQDGGCVPIGHCDC 4119

Query: 622  YH-RGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKP 680
               +G     G         C C+ G+L C       Q C  P  H   S+ +A +   P
Sbjct: 4120 TDAQGHSWAPGSQHQDACNNCSCQAGQLSC-----TAQPC-PPPTHCAWSHWSAWS---P 4170

Query: 681  RALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECP--CVHNNDLYSSG-AKIK 737
             + SC             SG   P+   +  +     +  CP  C+      + G + ++
Sbjct: 4171 CSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWLQ 4230

Query: 738  VDCNTCTCKRGRWVCTQAVC 757
             +C  C+C     +C    C
Sbjct: 4231 GECQRCSCTPEGVICEDTEC 4250



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 35/120 (29%), Positives = 48/120 (40%), Gaps = 15/120 (12%)

Query: 649  HCRQIRLIGQSCTAPKIHMDCSNLTALATSK------PRALSCQTLAAGYYHTECVSGCV 702
            +C   R  G+ C A  +    +N TA+  ++      P   SC  L    +   C  GC 
Sbjct: 3290 YCEGPRAQGEVCQA--LPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWR--CQPGCY 3345

Query: 703  CPDGLMDDGRGG-CVVEKECPCVH--NNDLYSSGAKIKVD--CNTCTCKRGRWVCTQAVC 757
            CP G +    G  CV    C C+       +  GA++     CN CTC  GR  CT   C
Sbjct: 3346 CPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPC 3405



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 49/205 (23%), Positives = 70/205 (34%), Gaps = 35/205 (17%)

Query: 2218 CLVECPSHREYQACGPAEEPTCKSSSSQ---QNNTVLVEGCFCPEGTMNYAPGFDVCVKT 2274
            C   CP+  E   C       C         Q++ V  +GC CP+G++    G  V +  
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGC-VPIGH 4116

Query: 2275 CGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVN 2334
            C C          G   +  C NC C  G      QP  C   P THC        +  +
Sbjct: 4117 CDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQP--C--PPPTHCAWSHW---SAWS 4169

Query: 2335 PADTCC----NITVCKCNTS-----LCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESKGV 2385
            P    C      +  + +TS      C+E+ S        +S+  P   CP        +
Sbjct: 4170 PCSHSCGPRGQQSRFRSSTSGSWAPECREEQS--------QSQPCPQPSCP-------PL 4214

Query: 2386 CVHGNAEYQPGSPVYSSKCQDCVCT 2410
            C+ G      G      +CQ C CT
Sbjct: 4215 CLQGTRSRTLGDSWLQGECQRCSCT 4239



 Score = 40.8 bits (94), Expect = 0.018
 Identities = 28/87 (32%), Positives = 32/87 (36%), Gaps = 5/87 (5%)

Query: 560  GSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKC 619
            G CP  + +L     C Q   S +E  +          GC CP    L     CVP   C
Sbjct: 3088 GMCPRDKQWL----DCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLL-LNNVCVPTQDC 3142

Query: 620  SCYHRGLYLEAGDVVVRQEERCVCRDG 646
             C H G     G  VVR  E C C  G
Sbjct: 3143 PCAHEGHLYPPGSTVVRPCENCSCVSG 3169



 Score = 40.0 bits (92), Expect = 0.030
 Identities = 31/108 (28%), Positives = 39/108 (36%), Gaps = 32/108 (29%)

Query: 2222 CPSHREYQACGPAEEPTCKSSSSQQNNTV------LVEGCFCPEGTMNYAPGFDVCVKTC 2275
            CP+ R Y+ C P E   C  S +     V        EGC CPEGT  +      CV+ C
Sbjct: 3697 CPAGRLYRECQPGEG--CPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRL---ACVQEC 3751

Query: 2276 GCV--------------------GPDNVPREFGEHFEFDCKNCVCLEG 2303
             CV                    GP +   + G+     C NC C  G
Sbjct: 3752 PCVLTAWLLQELGATIGDPGQPLGPGD-ELDSGQTLRTSCGNCSCAHG 3798



 Score = 39.3 bits (90), Expect = 0.052
 Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 19/95 (20%)

Query: 2359 CPLG--FEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNN 2416
            CPLG  ++ + + VP   CP         C  G   Y PGS     +C  C+C ++    
Sbjct: 862  CPLGLLWDPEGQCVPPSLCP---------CQLGARRYAPGSATMK-ECNRCICQER---- 907

Query: 2417 TLLNVIACTHVPCNTSCSPGFELMEAPGECCKKCE 2451
             L N  A  H P    C    EL+ APG C   C+
Sbjct: 908  GLWNCTA-RHCPSQAFCPR--ELVYAPGACLLTCD 939



 Score = 37.7 bits (86), Expect = 0.15
 Identities = 35/124 (28%), Positives = 46/124 (37%), Gaps = 21/124 (16%)

Query: 575  CQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGR-CVPLAKCSC--------YHRG 625
            C ++C  L     HC+    P  GC CP    L   G  CV    CSC        +H G
Sbjct: 3326 CPRSCDDLV----HCVWRCQP--GCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPG 3379

Query: 626  LYLEAGDVVVRQEERCVCRDGRLHCRQI--RLIGQSCTAPKIHMDCSNLTALATSKPRAL 683
              L   D        C C +GRL+C  +   + G  C   +  M          S+ RA 
Sbjct: 3380 ARLARPDGC----NHCTCLEGRLNCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRSRSRAC 3435

Query: 684  SCQT 687
            +C T
Sbjct: 3436 ACPT 3439



 Score = 37.0 bits (84), Expect = 0.26
 Identities = 53/234 (22%), Positives = 76/234 (32%), Gaps = 67/234 (28%)

Query: 893  CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE-APTCPDVSTNPEPCSLNPHRRSWAEKQ 951
            C   +H+S   FT      V  E    + W   +  C    T    C    H      + 
Sbjct: 1732 CPGPEHQSQACFTAA--CPVDGEWSTWSPWSVCSEPCRGTMTRQRQC----HSPQNGGRT 1785

Query: 952  CSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF 1011
            C+ L   +    HS    KP    C  D C   T       CS    + Q C        
Sbjct: 1786 CAALPGGL----HSTRQTKP----CPQDGCPNAT-------CSGELMF-QPCAP------ 1823

Query: 1012 WRTPDLCPIFCDYYNPPHEC--EWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCP 1069
                  CP+ CD  +    C  +W   PCG+                      GC+  CP
Sbjct: 1824 ------CPLTCDDISGQVTCPPDW---PCGS---------------------PGCW--CP 1851

Query: 1070 KDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCR 1123
            + + +  E    CV   +C C V+   Y PG  +  +  C+ C+C +     CR
Sbjct: 1852 EGQVLGSEGW--CVWPRQCPCLVDGARYWPGQRIKAD--CQLCICQDGRPRRCR 1901



 Score = 37.0 bits (84), Expect = 0.26
 Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 6/91 (6%)

Query: 1653 GSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAP 1712
            G   P + T T P++    S  P    + Q   +T  P  E+ TL    PP +   +  P
Sbjct: 2312 GQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIPQMEARTL----PPGMAAVTVVP 2367

Query: 1713 PSTPTAPTTTSGGHTLSPP-PSTTTSPPGTP 1742
            P  P  P T +G      P P     P  TP
Sbjct: 2368 PH-PVTPATPAGQSVAPGPFPPVQCGPGQTP 2397



 Score = 37.0 bits (84), Expect = 0.26
 Identities = 28/113 (24%), Positives = 44/113 (38%), Gaps = 30/113 (26%)

Query: 2201 CAQQNICLDWRNHTHGA-CLVECPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPE 2259
            C++ +    +  H  G+ C   C +H  +Q C   + P C+             GC+CP+
Sbjct: 4418 CSEDSCTPPFEFHACGSPCAGLCATHLSHQLC--QDLPPCQP------------GCYCPK 4463

Query: 2260 GTMNYAPGFDVCV--KTCGC-------VGPDNVPREFGEHFEFDCKNCVCLEG 2303
            G +  A G   C+  + C C        G    P   G+  +  CK C C  G
Sbjct: 4464 GLLEQAGG---CIPPEECNCWHTSAAGAGMTLAP---GDRLQLGCKECECRRG 4510



 Score = 35.8 bits (81), Expect = 0.58
 Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 20/144 (13%)

Query: 2222 CPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKT--CGCVG 2279
            CP  +++  C        + S+ +  N     GC CP G +      +VCV T  C C  
Sbjct: 3090 CPRDKQWLDCAQGPASCAELSAPRGTNQTCHPGCHCPSGMLLLN---NVCVPTQDCPCAH 3146

Query: 2280 PDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 2339
              ++    G      C+NC C+   SG+I     CS  P   C E G    +   P   C
Sbjct: 3147 EGHLYPP-GSTVVRPCENCSCV---SGLIA---NCSSWP---CAE-GEPTWSPWTPWSQC 3195

Query: 2340 ---CNITVCKCNTSLCKEKPSVCP 2360
               C    C      C   PS  P
Sbjct: 3196 SASCGPARCH-RHRFCARSPSAVP 3218



 Score = 35.4 bits (80), Expect = 0.75
 Identities = 30/106 (28%), Positives = 47/106 (44%), Gaps = 21/106 (19%)

Query: 1058 VSYLEG-CYP--RCPKDRPIYEEDLKKCVTADKCGCYVEDTH----YPPGASVPTEETCK 1110
            V  L+G C P  RCP  + + +    +CV    C C +   +      P  +V  +  C+
Sbjct: 4693 VQCLQGPCRPGCRCPPGQLVQDG---RCVPISSCRCGLPSANASWELAPAQAVQLD--CQ 4747

Query: 1111 SCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGP---NGTVEKH 1153
            +C C N S +VC  +E  +L     G +  W  C      GT+E+H
Sbjct: 4748 NCTCVNES-LVCPHQECPVL-----GPWSAWSSCSAPCGGGTMERH 4787



 Score = 33.9 bits (76), Expect = 2.2
 Identities = 58/254 (22%), Positives = 87/254 (34%), Gaps = 73/254 (28%)

Query: 2221 ECPSHREYQACGPAEEPTCKSSSS----QQNNTVLVEGCFCPEGTMNY-----APGFDVC 2271
            +C   +    CG     +C+  S     Q  +      C CP G ++       P    C
Sbjct: 3528 DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC 3587

Query: 2272 VKTCGCVG-PDNVPREFGEHFEF------------DCKNCVCLEGGSGIICQPKRCSQKP 2318
                G +G P+N  R  G  F               C NC C+   +GI+    +C + P
Sbjct: 3588 QYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCV---AGIL----QCQEVP 3640

Query: 2319 VTHCVEDGTYLATEVNPADTC--------------CNITVC--------KCNTSLCKEKP 2356
               C + G +  +   P + C              C    C         C+T +C+E  
Sbjct: 3641 --DCPDPGVW--SSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCRE-- 3694

Query: 2357 SVCPLGFEVKSKMVPGRCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQD-CVCTDKVDN 2415
            + CP G  +  +  PG  CPF        C H     Q G   +S  C++ C C +    
Sbjct: 3695 AGCPAG-RLYRECQPGEGCPF-------SCAH--VTQQVG--CFSEGCEEGCHCPEGTFQ 3742

Query: 2416 NTLLNVIACTHVPC 2429
            + L  V  C   PC
Sbjct: 3743 HRLACVQEC---PC 3753



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 33/121 (27%), Positives = 44/121 (36%), Gaps = 13/121 (10%)

Query: 1064 CYP--RCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVV 1121
            C+P   CP    +       CV    C C  E   YPPG++V     C++C C +     
Sbjct: 3119 CHPGCHCPSGMLLLNN---VCVPTQDCPCAHEGHLYPPGSTV--VRPCENCSCVSGLIAN 3173

Query: 1122 CRP---EEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPTTP 1178
            C      EG+               CGP       F   S +  PST+     + LP TP
Sbjct: 3174 CSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTV---APLPLPATP 3230

Query: 1179 T 1179
            T
Sbjct: 3231 T 3231



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 29/122 (23%), Positives = 44/122 (36%), Gaps = 18/122 (14%)

Query: 237  CQDLVPLEPYLRACQQDRCRCPGG----------DTCVCSTVAEFSRQCSHA----GGRP 282
            C +++      R C    C  PGG          D       +  SR CS      GG P
Sbjct: 3983 CPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSCSSPPSKNGGAP 4042

Query: 283  --GNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHRM--DGCFCPE 338
              G    A           CP  +  +   + C   CS L+   +C++ ++   GC CP+
Sbjct: 4043 CAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPK 4102

Query: 339  GA 340
            G+
Sbjct: 4103 GS 4104



 Score = 32.7 bits (73), Expect = 4.9
 Identities = 26/95 (27%), Positives = 34/95 (35%), Gaps = 28/95 (29%)

Query: 248  RACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYL 307
            R C +  C  P   +  CST     + C  AG                    CP   +Y 
Sbjct: 3670 RRCARPPCPGPARQSRTCST-----QVCREAG--------------------CPAGRLYR 3704

Query: 308  ES--GSPCMDTCSHLEVSSLC-EEHRMDGCFCPEG 339
            E   G  C  +C+H+     C  E   +GC CPEG
Sbjct: 3705 ECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEG 3739



 Score = 32.7 bits (73), Expect = 4.9
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 9/81 (11%)

Query: 1044 ETCRTINGI--HSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGA 1101
            +TC  +N     SN S +   GC   C      +      CV  D C C+     + PG+
Sbjct: 4942 QTCLEMNATKTQSNCSSARASGCV--CQPGH--FRSQAGPCVPEDHCECWHLGRPHLPGS 4997

Query: 1102 SVPTEETCKSCVCTNSSQVVC 1122
                +E C+SC+C  S + VC
Sbjct: 4998 E--WQEACESCLCL-SGRPVC 5015



 Score = 32.3 bits (72), Expect = 6.4
 Identities = 56/222 (25%), Positives = 69/222 (31%), Gaps = 67/222 (30%)

Query: 2219 LVECPS-HREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGC 2277
            L  CP    + QAC  A  P     S+    +V  E C    GTM          +   C
Sbjct: 1729 LQNCPGPEHQSQACFTAACPVDGEWSTWSPWSVCSEPC---RGTMT---------RQRQC 1776

Query: 2278 VGPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPAD 2337
              P N  R            C  L GG     Q K C                    P D
Sbjct: 1777 HSPQNGGR-----------TCAALPGGLHSTRQTKPC--------------------PQD 1805

Query: 2338 TCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMV----------PGRCCP-------FYWC 2380
             C N T   C+  L  +  + CPL  +  S  V          PG  CP         WC
Sbjct: 1806 GCPNAT---CSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWC 1862

Query: 2381 --ESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLN 2420
                +  C+   A Y PG  +  + CQ C+C D       LN
Sbjct: 1863 VWPRQCPCLVDGARYWPGQRI-KADCQLCICQDGRPRRCRLN 1903



 Score = 32.3 bits (72), Expect = 6.4
 Identities = 62/280 (22%), Positives = 93/280 (33%), Gaps = 56/280 (20%)

Query: 2370 VPG---RCCPFYWCESKGVCVHGNAEYQPGSPVYSSKCQDCVCTDKVDNNTLLNVIACTH 2426
            VPG   R  P+ WC+    C  G +          SK     C  +     L     C  
Sbjct: 4003 VPGGWSRWSPWSWCDRS--CGGGQSLRSRSCSSPPSKNGGAPCAGERHQARL-----CNP 4055

Query: 2427 VPCNTSCSPGFELMEAPGECCKKCEQTHCIIKRPDNQHVILK-----PGDFKSDPKNNCT 2481
            +PC   C  G E++     C ++C      I   D+Q V  K      G  + D      
Sbjct: 4056 MPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQ-VCQKGCRCPKGSLEQDG----- 4109

Query: 2482 FFSCVKIHNQLISSVSNITCPNFDASICIPGSITFMPNGCCKTCTPRNETRVPCSTVPVT 2541
               CV I         +  C +       PGS        C  C+ +   ++ C+  P  
Sbjct: 4110 --GCVPI--------GHCDCTDAQGHSWAPGS---QHQDACNNCSCQ-AGQLSCTAQPCP 4155

Query: 2542 TEVSYAGCTKTVLMNHCSGSCGTFVMYSAKAQALDHSCS--CCKEEKTSQREVVLSCP-- 2597
               ++   +     + CS SCG     S    +   S +  C +E+  SQ     SCP  
Sbjct: 4156 PP-THCAWSHWSAWSPCSHSCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPSCPPL 4214

Query: 2598 -----NGGSLTHTYTHIESCQ----------CQDTVCGLP 2622
                    +L  ++   E CQ          C+DT C +P
Sbjct: 4215 CLQGTRSRTLGDSWLQGE-CQRCSCTPEGVICEDTECAVP 4253


>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
            sapiens]
          Length = 2250

 Score =  337 bits (864), Expect = 9e-92
 Identities = 197/652 (30%), Positives = 322/652 (49%), Gaps = 70/652 (10%)

Query: 389  SSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVE 448
            SS  I++    G+++   +    ++++ L  A + +  GLCG FNG   DDF + SG++E
Sbjct: 520  SSLFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIE 578

Query: 449  ATGAGFANTWKAQSSCHDKLDW-LDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVD 507
             T    AN W+  S+C   +   + DPC++N ++  YA H C ++   +  F  CH  + 
Sbjct: 579  GTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAH-CDVIH--QELFAPCHIYIS 635

Query: 508  PAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQV 567
            P  YY+ C++D C C ++  CLC AL+ YA  C   GV +  +R  +    V  C    +
Sbjct: 636  PGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGVPI-DFRTQISFCAV-VCQKGML 691

Query: 568  FLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEK-GRCVPLAKCSCYHRGL 626
            + +  + C  +C SLS  +  C +  A  +GC CP+  F ++    CVP+  C C++RG 
Sbjct: 692  YHHCSSFCLHSCISLSSPEQ-CSDDCA--EGCNCPEGKFYEDTLNFCVPIFHCRCHYRGS 748

Query: 627  YLEAGDVVVRQEERCVCRDGRLHCRQIRLIG--QSCTAPKIHMDCS--NLTALATSKPRA 682
              + G+++      C C +G + C ++        C   K + DC   +    A      
Sbjct: 749  VYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCE 808

Query: 683  LSCQTLAAGYYHTE---CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD 739
             +C  LA  +  T    C+SGCVC  G+                                
Sbjct: 809  TTCANLAMNFTCTPSSPCISGCVCAPGV-------------------------------- 836

Query: 740  CNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG 799
                 C+RG + CT   C   C+IYG  HY +FDG  YD+   C    ++     ++   
Sbjct: 837  -----CRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIK-----SADDS 886

Query: 800  SFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHV----AYTTREV 855
              S+I +N  C    + CSK++ I +G TE+ L D      Q+  G  +     Y   + 
Sbjct: 887  DISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYK--QKQSGFFLENKSTYQLWKA 944

Query: 856  GQYLVVE-SSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSS 914
            G Y+VV      I ++WD++TT+ IK+ P +K  + GLCGNFD  ++ND TT +++ V +
Sbjct: 945  GYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRN 1004

Query: 915  ELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYE 974
               FG+SW     C       +PC  + ++  +A+K+CSIL S +F+ C + +D   F +
Sbjct: 1005 ARVFGDSWALGQ-CESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAK 1063

Query: 975  ACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1026
             C  D+C+C+ GGDCEC C+++A+YA +C +EG  + WR+  +C + C+YYN
Sbjct: 1064 NCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCEYYN 1115



 Score =  202 bits (513), Expect = 5e-51
 Identities = 118/433 (27%), Positives = 207/433 (47%), Gaps = 35/433 (8%)

Query: 697  CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAV 756
            C+ GC CPDGL+ D  G C+  + CPC  +   YS G+KI+ +C  C C  G W CT+  
Sbjct: 361  CLDGCYCPDGLVMDN-GTCISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQD 419

Query: 757  CHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPC-GTTGV 815
            C   CS+ G  H+ TFDG++Y F G C Y+ V     + +    F+I  +  PC    G+
Sbjct: 420  CPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV-----KGTGKDKFTITLQKAPCEQNLGL 474

Query: 816  TCSKAIKIFMG---RTELKLEDKHRVVIQRDEGHH---VAYTTREVGQYLVVESSTGIIV 869
             C ++I + +      ++ L    +++   ++G +   +         +++++++ G+ +
Sbjct: 475  VCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKI 534

Query: 870  IWD-KRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC 928
            ++      ++I+L  ++K    GLCG F+    +DF +   M+  +     N+W+ + TC
Sbjct: 535  LFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTC 594

Query: 929  --PDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTG 986
              P      +PC++N     +A   C ++   +F+ CH  + P  +Y+ C HD+C C + 
Sbjct: 595  FAPVHVPVVDPCNINQQNIGYA-AHCDVIHQELFAPCHIYISPGLYYQLCRHDACKCGS- 652

Query: 987  GDCECFCSAVASYAQECTKEGACVFWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFET 1045
                C C+A+A YA  C + G  + +RT    C + C       +    Y  C +    +
Sbjct: 653  ---SCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVC-------QKGMLYHHCSSFCLHS 702

Query: 1046 CRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPT 1105
            C +++      S    EGC   CP+ +  YE+ L  CV    C C+   + Y PG  +PT
Sbjct: 703  CISLSS-PEQCSDDCAEGC--NCPEGK-FYEDTLNFCVPIFHCRCHYRGSVYQPGELIPT 758

Query: 1106 EETCKSCVCTNSS 1118
                  C C+N +
Sbjct: 759  PSGL--CQCSNGT 769



 Score =  172 bits (435), Expect = 5e-42
 Identities = 131/485 (27%), Positives = 214/485 (44%), Gaps = 46/485 (9%)

Query: 1913 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 1972
            MP C    +PV+V   D CC  WEC C C+   +   +TFDG   +     +Y+LV  I 
Sbjct: 1414 MPDCGFRGRPVQVNS-DICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILV-RIP 1471

Query: 1973 PSVDNFGVYIDNYHCDPNDKVS--CPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVA 2030
              +    +   + +  P+ ++S  C + L V     ++++       +  +V+V+   V 
Sbjct: 1472 GEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNR-----LARKVEVDSIVVP 1526

Query: 2031 LPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRLPY---HRFGNNTKGQCGTCTN 2087
            LP+    L +  SG  YV+  P  G+++ ++ L+  + + +       + T+G CG C  
Sbjct: 1527 LPFSSQELSIEDSGSMYVITTP-AGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNE 1585

Query: 2088 TTSDDCILPSGEIVSNCEAAA---DQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPH 2144
               DD  + +G I++N E      + W +    +        T +RP        +    
Sbjct: 1586 DPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFE-------VTMRRPV-------RNCTE 1631

Query: 2145 KDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQ 2204
             DC  S    L+   +F  CH  V P+ + +    +  +    + EC +L AY ALC + 
Sbjct: 1632 HDC--SQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYF--WNYECDALSAYVALCNKF 1687

Query: 2205 NICLDWRNHTHGACLVECPSHREYQAC-GPAEEPTCKSSSSQQNNTV--LVEGCFCPEGT 2261
            +IC+ WR  T   C + CP  +EYQ C  P E  TC +     + +   L E C C  GT
Sbjct: 1688 DICIQWR--TPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGT 1745

Query: 2262 MNYAPGFDVCV--KTCGCVGPDNVPREFGEHFEFDCKNCV---CLEGGSGIICQPKRCSQ 2316
            + + P    C+  K C C   ++ PR  GE +      C    CLE GS I  +P  C +
Sbjct: 1746 VLHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPD-CDE 1804

Query: 2317 KPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCP 2376
            +P   C  +   +   ++   TCC+  VC C+T+LC+     C    ++     P  CCP
Sbjct: 1805 EPTPVCEREAEVVMGIIDKW-TCCSKEVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCP 1863

Query: 2377 FYWCE 2381
             Y CE
Sbjct: 1864 QYKCE 1868



 Score =  134 bits (338), Expect = 9e-31
 Identities = 103/373 (27%), Positives = 162/373 (43%), Gaps = 43/373 (11%)

Query: 759  GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVP-CGTTGVTC 817
            G C  +G  H+ TFDG YY F G+CSY+  +D CG       +++   N P C  +  +C
Sbjct: 62   GICKTWGQYHFETFDGIYYYFPGNCSYIFAKD-CGDLEP--RYTVWVHNSPKCLGSVYSC 118

Query: 818  SKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTRE-VGQ--------YLVVESSTGII 868
             ++I +F    E     + R+     + + ++ T  + +GQ        Y++V+++ G  
Sbjct: 119  YRSISLFFSNQE-----EIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFS 173

Query: 869  VIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK----- 923
            + WD  + +++KL+  +KG  CGLCGN++   ++DF             F NSW      
Sbjct: 174  LAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPD 233

Query: 924  EAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSC 983
            +       S  P PCS           +C IL    F  CH  +DP  +  +CV+D C  
Sbjct: 234  DTKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKT 293

Query: 984  DTGGDCECFCSAVASYAQECTKEGACV-FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNR 1041
            D   D E +C A   YA+ C+  G  +  WR     C   CD      +C     P    
Sbjct: 294  D---DDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPP--TC 348

Query: 1042 SFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGA 1101
            +FE     + +H       L+GCY  CP    +   D   C++ + C C      Y  G+
Sbjct: 349  TFEKQCLGSNLHC------LDGCY--CPDGLVM---DNGTCISLENCPCGFHGLAYSVGS 397

Query: 1102 SVPTEETCKSCVC 1114
             +  E+ C  CVC
Sbjct: 398  KI--EQECTECVC 408



 Score =  134 bits (337), Expect = 1e-30
 Identities = 93/337 (27%), Positives = 140/337 (41%), Gaps = 22/337 (6%)

Query: 20  GSELQTEGRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLK 79
           G+  Q      N    +C TWG +H++TFDG  + FPG C Y FA DC      + V + 
Sbjct: 47  GTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVH 106

Query: 80  RGPGQAEAPAGVESILLTI-----KDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAY 134
             P   +    V S   +I       + I +  H    NG  ++ P     + IEK   Y
Sbjct: 107 NSP---KCLGSVYSCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADY 163

Query: 135 TKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEF--LSDGVLFSPLE 192
             V +  G +L W+    + L+L    +  +CGLCG+YN +QS  +F  L +        
Sbjct: 164 ILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQS-DDFIILQEDYTEDIAM 222

Query: 193 FGNMQKINQPDVVCEDPEEEVAPASCSEHRAECE------RLLTAEAFADCQDLVPLEPY 246
           F N   +  PD           P  CS      E      ++L    F  C + +    Y
Sbjct: 223 FANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLY 282

Query: 247 LRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVY 306
           + +C  D C+    +T  C    E++R CSHAG    +WR       P  +  C  + V+
Sbjct: 283 IASCVNDLCKTDDDET-YCRAATEYARACSHAGYPIQDWRDD----FPACTDKCDDSFVH 337

Query: 307 LESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGAQAD 343
            +  S C  TC+  +       H +DGC+CP+G   D
Sbjct: 338 RDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMD 374



 Score =  128 bits (321), Expect = 9e-29
 Identities = 135/518 (26%), Positives = 185/518 (35%), Gaps = 93/518 (17%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C   +C   C+  GD H+ TFDG +YS+ G C Y+LV+      D F + +    C+ N 
Sbjct: 415  CTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK--GTGKDKFTITLQKAPCEQNL 472

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
             + C +++ +  E                QV + R    L     G       +N +V+I
Sbjct: 473  GLVCLQSITLILEDD-----------FNKQVTLGRGGQILTSPNQGF-----NLNGIVEI 516

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFG------------NNTKGQCGTCTNTTSDDCILPSGE 2099
              L  L      +F +++ +   G              T G CGT      DD + PSG 
Sbjct: 517  QTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGM 576

Query: 2100 IVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDS 2159
            I    +  A+ W V           SST   P             ++   +  C +I   
Sbjct: 577  IEGTPQLHANAWRV-----------SSTCFAPVHVPVVDPCNINQQNIGYAAHCDVIHQE 625

Query: 2160 LFAQCHALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACL 2219
            LFA CH  + P  YY  C  D+C   GSS  C +L  YA LC Q  + +D+R      C 
Sbjct: 626  LFAPCHIYISPGLYYQLCRHDAC-KCGSSCLCNALAHYAYLCGQHGVPIDFRTQI-SFCA 683

Query: 2220 VECPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCV 2278
            V C     Y  C      +C S SS +Q +    EGC CPEG   Y    + CV      
Sbjct: 684  VVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKF-YEDTLNFCVPIF--- 739

Query: 2279 GPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADT 2338
                              +C C   GS  + QP      P   C                
Sbjct: 740  ------------------HCRCHYRGS--VYQPGELIPTPSGLC---------------Q 764

Query: 2339 CCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPF--YWCESKGVCVHGNAEYQPG 2396
            C N TV KC+         +CP G E      P    P     CE+    +  N    P 
Sbjct: 765  CSNGTV-KCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPS 823

Query: 2397 SPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434
            SP  S     CVC   V    + N   CT+ PC   C+
Sbjct: 824  SPCISG----CVCAPGVCRRGMFN---CTYYPCPAVCT 854



 Score =  122 bits (306), Expect = 5e-27
 Identities = 103/412 (25%), Positives = 161/412 (39%), Gaps = 42/412 (10%)

Query: 257 CPGGDTCVCSTVAEFSRQC----SHAGGRPG---NWRTATSAVSPGASKTCPGNLVYLES 309
           C    TC C        +C    +   GR G    W         G     PGN  Y+ +
Sbjct: 32  CSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFA 91

Query: 310 GSPCMDTCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSDGSVLL 369
                  C  LE       H    C    G+     +++ L    ++ + ++  +  +  
Sbjct: 92  KD-----CGDLEPRYTVWVHNSPKCL---GSVYSCYRSISLFFSNQEEIRIYGHE--IKK 141

Query: 370 NELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLC 429
           N + + LP       + + + Y I+V    G  L      +  +++ L +  +G+  GLC
Sbjct: 142 NGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWD--GISGIYLKLSEDHKGKSCGLC 198

Query: 430 GNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKL----DWLDDPCSLNIESANYA 485
           GN+N ++ DDF           A FAN+W  Q+    K         +PCS  + +    
Sbjct: 199 GNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAI 258

Query: 486 EHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGV 545
              C +L   + PF  CH  +DP  Y   C  D C   ++E   C A + YARAC+  G 
Sbjct: 259 FFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET-YCRAATEYARACSHAGY 315

Query: 546 MLWGWREH--VCNKDVGSCPNSQVFLYNLTTCQQTC---RSLSEADSHCLEGFAPVDGCG 600
            +  WR+    C      C +S V    ++ C  TC   +    ++ HCL      DGC 
Sbjct: 316 PIQDWRDDFPACTD---KCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCL------DGCY 366

Query: 601 CPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQ 652
           CPD   +D  G C+ L  C C   GL    G  + ++   CVC  G  +C +
Sbjct: 367 CPDGLVMDN-GTCISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTE 417



 Score =  122 bits (306), Expect = 5e-27
 Identities = 93/372 (25%), Positives = 156/372 (41%), Gaps = 27/372 (7%)

Query: 1938 DCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPR 1997
            D  C  WG  H+ TFDG+YY + GNC+Y+  ++       + V++ N         SC R
Sbjct: 61   DGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYR 120

Query: 1998 TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVL 2057
            ++ +    QE +    H      +++ N  ++ LP +  G    +   +Y++     G  
Sbjct: 121  SISLFFSNQEEIRIYGH------EIKKNGISLTLP-QTIGQIFIEKLADYILVKTTFGFS 173

Query: 2058 VSYNGLS-FSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDP 2116
            ++++G+S   ++L     G +  G CG   +  SDD I+   +   +    A+ W V  P
Sbjct: 174  LAWDGISGIYLKLSEDHKGKSC-GLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTP 232

Query: 2117 SKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDA 2176
                C  + S    P  +     +    K       CQ++    F  CH  + P  Y  +
Sbjct: 233  DDTKCVLTPSDFPNPCSSGMPAFEAIFFK-------CQILLQFPFLSCHEYIDPYLYIAS 285

Query: 2177 CVFDSCFMPGSSLECASLQAYAALCAQQNICL-DWRNHTHGACLVECPS---HREYQACG 2232
            CV D C        C +   YA  C+     + DWR+    AC  +C     HR+  +C 
Sbjct: 286  CVNDLCKTDDDETYCRAATEYARACSHAGYPIQDWRD-DFPACTDKCDDSFVHRDCISCC 344

Query: 2233 PAEEPTCK-SSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHF 2291
            P   PTC        +N   ++GC+CP+G +    G  + ++ C C G   +    G   
Sbjct: 345  P---PTCTFEKQCLGSNLHCLDGCYCPDGLV-MDNGTCISLENCPC-GFHGLAYSVGSKI 399

Query: 2292 EFDCKNCVCLEG 2303
            E +C  CVC+ G
Sbjct: 400  EQECTECVCVGG 411



 Score =  107 bits (268), Expect = 1e-22
 Identities = 87/354 (24%), Positives = 127/354 (35%), Gaps = 55/354 (15%)

Query: 2309 CQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSK 2368
            C  + C+ KPV  C  DG +L  ++N    CC    C C  +LC      C     +  +
Sbjct: 1903 CVCESCT-KPVPLC-HDGEFLTVDLNSTHFCCPQYYCVCEPNLCPMPLLNCAEDMNLVKE 1960

Query: 2369 MVPGRCCPF-----------------------------------YWCESKGVCVHGNAEY 2393
             V G+CCP                                    Y CE   VCV      
Sbjct: 1961 NVSGQCCPTWHCECNCENLVMPTCEVGEFTAIDHNFQSDCGCIQYLCEKDDVCVFQEVSV 2020

Query: 2394 -QPGSPVYS----SKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGE--C 2446
              PG  +        C    C ++ DN+T  + +  T V C+  C        +P +  C
Sbjct: 2021 LNPGQSMIKYLEEDFCYTIECLEEKDNHTGFHTLNFTLVNCSKKCDVHQVYTPSPSDYGC 2080

Query: 2447 CKKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDA 2506
            C  C+   C     +   V+   G   S    NCT + CVK     I     + CP F+ 
Sbjct: 2081 CGTCKNVSCKFHMENGTSVVYAVG---STWHYNCTTYECVKTDEGAIILNYTMVCPPFNE 2137

Query: 2507 SIC--IPGSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGCTKTVLMN--HCSGSC 2562
            + C    G +     GCCK C  + E R+ C  V + + +    C     +N   C G C
Sbjct: 2138 TECKMSEGIVKLYNEGCCKIC--KREERI-CQKVIIKSVIRKQDCMSQSPINVASCDGKC 2194

Query: 2563 GTFVMYSAKAQALDHSCSCCKEEKTSQREVVLSCP-NGGSLTHTYTHIESCQCQ 2615
             +  +Y+   ++    C CC+E       V L C  NG  + +T      C CQ
Sbjct: 2195 PSATIYNINIESHLRFCKCCRENGVRNLSVPLYCSGNGTEIMYTLQEPIDCTCQ 2248



 Score = 95.5 bits (236), Expect = 6e-19
 Identities = 79/319 (24%), Positives = 149/319 (46%), Gaps = 33/319 (10%)

Query: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKE-FAVHLKRGPGQAEAP-AGVESI 94
           CS  G+ H+ TFDG  + F G+C Y      +G+ K+ F + L++ P +       ++SI
Sbjct: 424 CSVVGDSHFTTFDGRHYSFIGMCQYILV---KGTGKDKFTITLQKAPCEQNLGLVCLQSI 480

Query: 95  LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGL--LIE---KSDAYTKVYSRAGLTLMWNR 149
            L ++DD  +  +      G ++++P+    L  ++E    S  +  + +  GL +++  
Sbjct: 481 TLILEDD--FNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAI 538

Query: 150 E-DALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLF--SPLEFGNMQKINQPDVVC 206
           + + + ++L + ++  T GLCG +NG     +FLS   +   +P    N  +++     C
Sbjct: 539 DGERIYIQLTSAWKRRTLGLCGTFNG-NIRDDFLSPSGMIEGTPQLHANAWRVSS---TC 594

Query: 207 EDPEEEVAPASCSEHR------AECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGG 260
             P        C+ ++      A C+ ++  E FA C   +    Y + C+ D C+C  G
Sbjct: 595 FAPVHVPVVDPCNINQQNIGYAAHCD-VIHQELFAPCHIYISPGLYYQLCRHDACKC--G 651

Query: 261 DTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHL 320
            +C+C+ +A ++  C   G  P ++RT  S      +  C   ++Y    S C+ +C  L
Sbjct: 652 SSCLCNALAHYAYLCGQHGV-PIDFRTQISF----CAVVCQKGMLYHHCSSFCLHSCISL 706

Query: 321 EVSSLCEEHRMDGCFCPEG 339
                C +   +GC CPEG
Sbjct: 707 SSPEQCSDDCAEGCNCPEG 725



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 76/307 (24%), Positives = 121/307 (39%), Gaps = 33/307 (10%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C ++ C   CT +GD HY +FDGL Y Y  +C   L++    S  +  V   N  C  ND
Sbjct: 844  CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDS--DISVIAQNKKCFDND 901

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
             V     LI   +T+  L  T +           +Q+      K   +++++G   VV  
Sbjct: 902  IVCSKSVLISVGDTEIYLNDTPYKQ---------KQSGFFLENKSTYQLWKAGYYIVVYF 952

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 2111
            PE  + + ++  +        ++ N   G CG     TS+D    +   V N     D W
Sbjct: 953  PEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW 1012

Query: 2112 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--SPLCQLIKDSLFAQCHALVP 2169
             +     P        T +P            H++  P     C ++   +FA C  ++ 
Sbjct: 1013 ALGQCESP------DETIKPCEA---------HQNKFPYAKKECSILYSDIFASCRNVID 1057

Query: 2170 PQHYYDACVFDSCFMP-GSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLVECPSHR 2226
               +   C  D+C    G   EC   S+ AYA  C Q+ I + WR+ T   C ++C  + 
Sbjct: 1058 VTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSST--VCSLDCEYYN 1115

Query: 2227 EYQACGP 2233
            E    GP
Sbjct: 1116 EGLGEGP 1122



 Score = 85.9 bits (211), Expect = 5e-16
 Identities = 63/279 (22%), Positives = 129/279 (46%), Gaps = 50/279 (17%)

Query: 36   VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCR------GSYKEFAVHLKRGPGQAEAPA 89
            VC+ +G+ HY +FDG         +Y++ SDC+          + +V  +          
Sbjct: 852  VCTIYGDRHYYSFDG--------LEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV 903

Query: 90   GVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSP--GLLIEKSDAY---------TKVY 138
              +S+L+++ D  IYL             TP+     G  +E    Y            +
Sbjct: 904  CSKSVLISVGDTEIYLN-----------DTPYKQKQSGFFLENKSTYQLWKAGYYIVVYF 952

Query: 139  SRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGV-LFSPLEFGNMQ 197
                +T++W+R+  + +++  +++N   GLCG+++   S     S+ + + +   FG+  
Sbjct: 953  PEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW 1012

Query: 198  KINQPDVVCEDPEEEVAPASCSEHR-----AECERLLTAEAFADCQDLVPLEPYLRACQQ 252
             + Q    CE P+E + P    +++      EC  +L ++ FA C++++ +  + + C +
Sbjct: 1013 ALGQ----CESPDETIKPCEAHQNKFPYAKKECS-ILYSDIFASCRNVIDVTSFAKNCHE 1067

Query: 253  DRCRCP-GGD-TCVCSTVAEFSRQCSHAGGRPGNWRTAT 289
            D C C  GGD  C+C+++A ++ +C    G   +WR++T
Sbjct: 1068 DTCNCNLGGDCECLCTSIAAYAYKCCQE-GISIHWRSST 1105



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 96/453 (21%), Positives = 155/453 (34%), Gaps = 70/453 (15%)

Query: 733  GAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYC 792
            G  ++V+ + C        C +  C   CS+      ITFDG         SY+ V+   
Sbjct: 1421 GRPVQVNSDIC--------CPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVR-IP 1471

Query: 793  GQNSSLGSFSIITENVPCGTTGVTCSKAI-------KIFMGRTELKLEDKHRVVIQRDEG 845
            G+              P G     C K +       KI + R   K+E    VV      
Sbjct: 1472 GEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSS 1531

Query: 846  HHVAYTTREVGQYLVVESSTGIIVIWDKRTTV------FIKLAPSYKGTVCGLCGNFDHR 899
              ++    + G   V+ +  G+I+ W   T +      F     SY   +CG+C   +  
Sbjct: 1532 QELSI--EDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGIC---NED 1586

Query: 900  SNNDFTTRDHMVVSSELDFG---NSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCS--- 953
             ++D   ++  ++++  D G    SW+   +       P         R+  E  CS   
Sbjct: 1587 PDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPV--------RNCTEHDCSQCI 1638

Query: 954  -ILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFW 1012
             +L   +F  CH KV P+ F   C     +     + EC   A+++Y   C K   C+ W
Sbjct: 1639 DLLNRRIFIPCHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQW 1693

Query: 1013 RTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDR 1072
            RTPD C + C        C     PC  R   TC           ++  E C   C    
Sbjct: 1694 RTPDYCSLSCPEGKEYQPC---VRPCEAR---TCLNQWFYGHTSCLNLREDCV--CKVGT 1745

Query: 1073 PIYEEDLKKCVTADKCGCYVEDTHYPPGASV----PTEETCKSCV-----------CTNS 1117
             ++     +C+   +C C   +        +      E T   C+           C   
Sbjct: 1746 VLHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEE 1805

Query: 1118 SQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1150
               VC  E   ++        C  E+CG + T+
Sbjct: 1806 PTPVCEREAEVVMGIIDKWTCCSKEVCGCDTTL 1838



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 27/71 (38%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 1031 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1090
            CEW YEPC    F+TC     +     +  +EGC P CPK+  I +E   KCV    C  
Sbjct: 1277 CEWRYEPCATPCFKTCSDPEALACKF-LPPVEGCLPYCPKNM-ILDEVTLKCVYPRDCIP 1334

Query: 1091 YV--EDTHYPP 1099
             +  E T  PP
Sbjct: 1335 VIPTEPTLMPP 1345



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 59/276 (21%), Positives = 105/276 (38%), Gaps = 33/276 (11%)

Query: 358  VVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTL 417
            ++V +    V ++ + V LP  +   S+    S +++ + A  +     L  ++ +    
Sbjct: 1509 IIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGF 1568

Query: 418  DQASQGQVQGLCGNFNGLEGDDFKTASGLV----EATGAGFANTWKAQSSCHDKLDWLDD 473
                    +GLCG  N    DD +  +G +    E  G  F  +W+ + S          
Sbjct: 1569 RFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGL-FIESWEIEKSFE-------- 1619

Query: 474  PCSLNIESANYAEHWCS----LLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCL 529
              ++     N  EH CS    LL +    F  CH  V P ++ ++   +     N E   
Sbjct: 1620 -VTMRRPVRNCTEHDCSQCIDLLNR--RIFIPCHDKVSPEDFCEKMWINYTYFWNYE--- 1673

Query: 530  CAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQ-QTC-RSLSEADS 587
            C ALS+Y   C    + +       C+    SCP  + +   +  C+ +TC        +
Sbjct: 1674 CDALSAYVALCNKFDICIQWRTPDYCSL---SCPEGKEYQPCVRPCEARTCLNQWFYGHT 1730

Query: 588  HCLEGFAPVDGCGCPDHTFL--DEKGRCVPLAKCSC 621
             CL      + C C   T L      +C+P  +C+C
Sbjct: 1731 SCLN---LREDCVCKVGTVLHRPHSAQCIPEKECAC 1763



 Score = 35.4 bits (80), Expect = 0.75
 Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 3/70 (4%)

Query: 1876 DPPRQENETW--WLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVR-VEDPDGCC 1932
            D PR   E W   + +C +  C  N ++  ++ +C+  P P C    + V  + D   CC
Sbjct: 1768 DQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCC 1827

Query: 1933 WHWECDCYCT 1942
                C C  T
Sbjct: 1828 SKEVCGCDTT 1837



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 59/261 (22%), Positives = 98/261 (37%), Gaps = 37/261 (14%)

Query: 112  LNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFR----NHTCG 167
            ++  VV  P  S  L IE S +   + + AGL + W+    + +++   FR    ++T G
Sbjct: 1520 VDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGI-IDIHFGFRFNLSSYTEG 1578

Query: 168  LCGDYNGLQSYSEFLSDGVLFSPLE----FGNMQKINQP-DVVCEDPEEEVAPASCSEHR 222
            LCG  N        + +G + + +E    F    +I +  +V    P       +C+EH 
Sbjct: 1579 LCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVR-----NCTEHD 1633

Query: 223  -AECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGR 281
             ++C  LL    F  C D V  E +   C++            C  ++ +   C+     
Sbjct: 1634 CSQCIDLLNRRIFIPCHDKVSPEDF---CEKMWINYTYFWNYECDALSAYVALCNKF-DI 1689

Query: 282  PGNWRTATSAVSPGASKTCPGNLVYLESGSPC-MDTC------SHLEVSSLCEEHRMDGC 334
               WRT         S +CP    Y     PC   TC       H    +L E+     C
Sbjct: 1690 CIQWRTPDY-----CSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLRED-----C 1739

Query: 335  FCPEGAQADLPKTVVLLADKK 355
             C  G     P +   + +K+
Sbjct: 1740 VCKVGTVLHRPHSAQCIPEKE 1760



 Score = 34.3 bits (77), Expect = 1.7
 Identities = 25/101 (24%), Positives = 40/101 (39%), Gaps = 13/101 (12%)

Query: 1867 TKP-PECPDFDPPRQE-NETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVR 1924
            TKP P C D +    + N T + C  +   C+ N           P P+  C+  +  V+
Sbjct: 1909 TKPVPLCHDGEFLTVDLNSTHFCCPQYYCVCEPNLC---------PMPLLNCAEDMNLVK 1959

Query: 1925 VEDPDGCCWHWECDCYCTGWGDP--HYVTFDGLYYSYQGNC 1963
                  CC  W C+C C     P      F  + +++Q +C
Sbjct: 1960 ENVSGQCCPTWHCECNCENLVMPTCEVGEFTAIDHNFQSDC 2000



 Score = 32.3 bits (72), Expect = 6.4
 Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 16/78 (20%)

Query: 1870 PECPDFDPPRQENETW--------WLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQ 1921
            P+C +   P  E E          W C C    C  + T+      CE   +PTC+N  +
Sbjct: 1800 PDCDEEPTPVCEREAEVVMGIIDKWTC-CSKEVCGCDTTL------CETS-IPTCTNSQK 1851

Query: 1922 PVRVEDPDGCCWHWECDC 1939
             +    P  CC  ++C+C
Sbjct: 1852 LIVGHSPLSCCPQYKCEC 1869


>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
            sapiens]
          Length = 2250

 Score =  337 bits (864), Expect = 9e-92
 Identities = 197/652 (30%), Positives = 322/652 (49%), Gaps = 70/652 (10%)

Query: 389  SSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVE 448
            SS  I++    G+++   +    ++++ L  A + +  GLCG FNG   DDF + SG++E
Sbjct: 520  SSLFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIE 578

Query: 449  ATGAGFANTWKAQSSCHDKLDW-LDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVD 507
             T    AN W+  S+C   +   + DPC++N ++  YA H C ++   +  F  CH  + 
Sbjct: 579  GTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAH-CDVIH--QELFAPCHIYIS 635

Query: 508  PAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQV 567
            P  YY+ C++D C C ++  CLC AL+ YA  C   GV +  +R  +    V  C    +
Sbjct: 636  PGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGVPI-DFRTQISFCAV-VCQKGML 691

Query: 568  FLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEK-GRCVPLAKCSCYHRGL 626
            + +  + C  +C SLS  +  C +  A  +GC CP+  F ++    CVP+  C C++RG 
Sbjct: 692  YHHCSSFCLHSCISLSSPEQ-CSDDCA--EGCNCPEGKFYEDTLNFCVPIFHCRCHYRGS 748

Query: 627  YLEAGDVVVRQEERCVCRDGRLHCRQIRLIG--QSCTAPKIHMDCS--NLTALATSKPRA 682
              + G+++      C C +G + C ++        C   K + DC   +    A      
Sbjct: 749  VYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCE 808

Query: 683  LSCQTLAAGYYHTE---CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD 739
             +C  LA  +  T    C+SGCVC  G+                                
Sbjct: 809  TTCANLAMNFTCTPSSPCISGCVCAPGV-------------------------------- 836

Query: 740  CNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG 799
                 C+RG + CT   C   C+IYG  HY +FDG  YD+   C    ++     ++   
Sbjct: 837  -----CRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIK-----SADDS 886

Query: 800  SFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHV----AYTTREV 855
              S+I +N  C    + CSK++ I +G TE+ L D      Q+  G  +     Y   + 
Sbjct: 887  DISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYK--QKQSGFFLENKSTYQLWKA 944

Query: 856  GQYLVVE-SSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSS 914
            G Y+VV      I ++WD++TT+ IK+ P +K  + GLCGNFD  ++ND TT +++ V +
Sbjct: 945  GYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRN 1004

Query: 915  ELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYE 974
               FG+SW     C       +PC  + ++  +A+K+CSIL S +F+ C + +D   F +
Sbjct: 1005 ARVFGDSWALGQ-CESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAK 1063

Query: 975  ACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1026
             C  D+C+C+ GGDCEC C+++A+YA +C +EG  + WR+  +C + C+YYN
Sbjct: 1064 NCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCEYYN 1115



 Score =  202 bits (513), Expect = 5e-51
 Identities = 118/433 (27%), Positives = 207/433 (47%), Gaps = 35/433 (8%)

Query: 697  CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAV 756
            C+ GC CPDGL+ D  G C+  + CPC  +   YS G+KI+ +C  C C  G W CT+  
Sbjct: 361  CLDGCYCPDGLVMDN-GTCISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQD 419

Query: 757  CHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPC-GTTGV 815
            C   CS+ G  H+ TFDG++Y F G C Y+ V     + +    F+I  +  PC    G+
Sbjct: 420  CPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV-----KGTGKDKFTITLQKAPCEQNLGL 474

Query: 816  TCSKAIKIFMG---RTELKLEDKHRVVIQRDEGHH---VAYTTREVGQYLVVESSTGIIV 869
             C ++I + +      ++ L    +++   ++G +   +         +++++++ G+ +
Sbjct: 475  VCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKI 534

Query: 870  IWD-KRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC 928
            ++      ++I+L  ++K    GLCG F+    +DF +   M+  +     N+W+ + TC
Sbjct: 535  LFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTC 594

Query: 929  --PDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTG 986
              P      +PC++N     +A   C ++   +F+ CH  + P  +Y+ C HD+C C + 
Sbjct: 595  FAPVHVPVVDPCNINQQNIGYA-AHCDVIHQELFAPCHIYISPGLYYQLCRHDACKCGS- 652

Query: 987  GDCECFCSAVASYAQECTKEGACVFWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFET 1045
                C C+A+A YA  C + G  + +RT    C + C       +    Y  C +    +
Sbjct: 653  ---SCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVC-------QKGMLYHHCSSFCLHS 702

Query: 1046 CRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPT 1105
            C +++      S    EGC   CP+ +  YE+ L  CV    C C+   + Y PG  +PT
Sbjct: 703  CISLSS-PEQCSDDCAEGC--NCPEGK-FYEDTLNFCVPIFHCRCHYRGSVYQPGELIPT 758

Query: 1106 EETCKSCVCTNSS 1118
                  C C+N +
Sbjct: 759  PSGL--CQCSNGT 769



 Score =  172 bits (435), Expect = 5e-42
 Identities = 131/485 (27%), Positives = 214/485 (44%), Gaps = 46/485 (9%)

Query: 1913 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 1972
            MP C    +PV+V   D CC  WEC C C+   +   +TFDG   +     +Y+LV  I 
Sbjct: 1414 MPDCGFRGRPVQVNS-DICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILV-RIP 1471

Query: 1973 PSVDNFGVYIDNYHCDPNDKVS--CPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVA 2030
              +    +   + +  P+ ++S  C + L V     ++++       +  +V+V+   V 
Sbjct: 1472 GEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNR-----LARKVEVDSIVVP 1526

Query: 2031 LPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRLPY---HRFGNNTKGQCGTCTN 2087
            LP+    L +  SG  YV+  P  G+++ ++ L+  + + +       + T+G CG C  
Sbjct: 1527 LPFSSQELSIEDSGSMYVITTP-AGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNE 1585

Query: 2088 TTSDDCILPSGEIVSNCEAAA---DQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPH 2144
               DD  + +G I++N E      + W +    +        T +RP        +    
Sbjct: 1586 DPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFE-------VTMRRPV-------RNCTE 1631

Query: 2145 KDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQ 2204
             DC  S    L+   +F  CH  V P+ + +    +  +    + EC +L AY ALC + 
Sbjct: 1632 HDC--SQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYF--WNYECDALSAYVALCNKF 1687

Query: 2205 NICLDWRNHTHGACLVECPSHREYQAC-GPAEEPTCKSSSSQQNNTV--LVEGCFCPEGT 2261
            +IC+ WR  T   C + CP  +EYQ C  P E  TC +     + +   L E C C  GT
Sbjct: 1688 DICIQWR--TPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGT 1745

Query: 2262 MNYAPGFDVCV--KTCGCVGPDNVPREFGEHFEFDCKNCV---CLEGGSGIICQPKRCSQ 2316
            + + P    C+  K C C   ++ PR  GE +      C    CLE GS I  +P  C +
Sbjct: 1746 ILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPD-CDE 1804

Query: 2317 KPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCP 2376
            +P   C  +   +   ++   TCC+  VC C+T+LC+     C    ++     P  CCP
Sbjct: 1805 EPTPVCEREAEVVMGIIDKW-TCCSKEVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCP 1863

Query: 2377 FYWCE 2381
             Y CE
Sbjct: 1864 QYKCE 1868



 Score =  134 bits (338), Expect = 9e-31
 Identities = 103/373 (27%), Positives = 162/373 (43%), Gaps = 43/373 (11%)

Query: 759  GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVP-CGTTGVTC 817
            G C  +G  H+ TFDG YY F G+CSY+  +D CG       +++   N P C  +  +C
Sbjct: 62   GICKTWGQYHFETFDGIYYYFPGNCSYIFAKD-CGDLEP--RYTVWVHNSPKCLGSVYSC 118

Query: 818  SKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTRE-VGQ--------YLVVESSTGII 868
             ++I +F    E     + R+     + + ++ T  + +GQ        Y++V+++ G  
Sbjct: 119  YRSISLFFSNQE-----EIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFS 173

Query: 869  VIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK----- 923
            + WD  + +++KL+  +KG  CGLCGN++   ++DF             F NSW      
Sbjct: 174  LAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPD 233

Query: 924  EAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSC 983
            +       S  P PCS           +C IL    F  CH  +DP  +  +CV+D C  
Sbjct: 234  DTKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKT 293

Query: 984  DTGGDCECFCSAVASYAQECTKEGACV-FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNR 1041
            D   D E +C A   YA+ C+  G  +  WR     C   CD      +C     P    
Sbjct: 294  D---DDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPP--TC 348

Query: 1042 SFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGA 1101
            +FE     + +H       L+GCY  CP    +   D   C++ + C C      Y  G+
Sbjct: 349  TFEKQCLGSNLHC------LDGCY--CPDGLVM---DNGTCISLENCPCGFHGLAYSVGS 397

Query: 1102 SVPTEETCKSCVC 1114
             +  E+ C  CVC
Sbjct: 398  KI--EQECTECVC 408



 Score =  134 bits (337), Expect = 1e-30
 Identities = 93/337 (27%), Positives = 140/337 (41%), Gaps = 22/337 (6%)

Query: 20  GSELQTEGRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLK 79
           G+  Q      N    +C TWG +H++TFDG  + FPG C Y FA DC      + V + 
Sbjct: 47  GTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVH 106

Query: 80  RGPGQAEAPAGVESILLTI-----KDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAY 134
             P   +    V S   +I       + I +  H    NG  ++ P     + IEK   Y
Sbjct: 107 NSP---KCLGSVYSCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADY 163

Query: 135 TKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEF--LSDGVLFSPLE 192
             V +  G +L W+    + L+L    +  +CGLCG+YN +QS  +F  L +        
Sbjct: 164 ILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQS-DDFIILQEDYTEDIAM 222

Query: 193 FGNMQKINQPDVVCEDPEEEVAPASCSEHRAECE------RLLTAEAFADCQDLVPLEPY 246
           F N   +  PD           P  CS      E      ++L    F  C + +    Y
Sbjct: 223 FANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLY 282

Query: 247 LRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVY 306
           + +C  D C+    +T  C    E++R CSHAG    +WR       P  +  C  + V+
Sbjct: 283 IASCVNDLCKTDDDET-YCRAATEYARACSHAGYPIQDWRDD----FPACTDKCDDSFVH 337

Query: 307 LESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGAQAD 343
            +  S C  TC+  +       H +DGC+CP+G   D
Sbjct: 338 RDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMD 374



 Score =  128 bits (321), Expect = 9e-29
 Identities = 135/518 (26%), Positives = 185/518 (35%), Gaps = 93/518 (17%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C   +C   C+  GD H+ TFDG +YS+ G C Y+LV+      D F + +    C+ N 
Sbjct: 415  CTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK--GTGKDKFTITLQKAPCEQNL 472

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
             + C +++ +  E                QV + R    L     G       +N +V+I
Sbjct: 473  GLVCLQSITLILEDD-----------FNKQVTLGRGGQILTSPNQGF-----NLNGIVEI 516

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFG------------NNTKGQCGTCTNTTSDDCILPSGE 2099
              L  L      +F +++ +   G              T G CGT      DD + PSG 
Sbjct: 517  QTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGM 576

Query: 2100 IVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDS 2159
            I    +  A+ W V           SST   P             ++   +  C +I   
Sbjct: 577  IEGTPQLHANAWRV-----------SSTCFAPVHVPVVDPCNINQQNIGYAAHCDVIHQE 625

Query: 2160 LFAQCHALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACL 2219
            LFA CH  + P  YY  C  D+C   GSS  C +L  YA LC Q  + +D+R      C 
Sbjct: 626  LFAPCHIYISPGLYYQLCRHDAC-KCGSSCLCNALAHYAYLCGQHGVPIDFRTQI-SFCA 683

Query: 2220 VECPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCV 2278
            V C     Y  C      +C S SS +Q +    EGC CPEG   Y    + CV      
Sbjct: 684  VVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKF-YEDTLNFCVPIF--- 739

Query: 2279 GPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADT 2338
                              +C C   GS  + QP      P   C                
Sbjct: 740  ------------------HCRCHYRGS--VYQPGELIPTPSGLC---------------Q 764

Query: 2339 CCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPF--YWCESKGVCVHGNAEYQPG 2396
            C N TV KC+         +CP G E      P    P     CE+    +  N    P 
Sbjct: 765  CSNGTV-KCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPS 823

Query: 2397 SPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434
            SP  S     CVC   V    + N   CT+ PC   C+
Sbjct: 824  SPCISG----CVCAPGVCRRGMFN---CTYYPCPAVCT 854



 Score =  122 bits (306), Expect = 5e-27
 Identities = 103/412 (25%), Positives = 161/412 (39%), Gaps = 42/412 (10%)

Query: 257 CPGGDTCVCSTVAEFSRQC----SHAGGRPG---NWRTATSAVSPGASKTCPGNLVYLES 309
           C    TC C        +C    +   GR G    W         G     PGN  Y+ +
Sbjct: 32  CSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFA 91

Query: 310 GSPCMDTCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSDGSVLL 369
                  C  LE       H    C    G+     +++ L    ++ + ++  +  +  
Sbjct: 92  KD-----CGDLEPRYTVWVHNSPKCL---GSVYSCYRSISLFFSNQEEIRIYGHE--IKK 141

Query: 370 NELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLC 429
           N + + LP       + + + Y I+V    G  L      +  +++ L +  +G+  GLC
Sbjct: 142 NGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWD--GISGIYLKLSEDHKGKSCGLC 198

Query: 430 GNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKL----DWLDDPCSLNIESANYA 485
           GN+N ++ DDF           A FAN+W  Q+    K         +PCS  + +    
Sbjct: 199 GNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAI 258

Query: 486 EHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGV 545
              C +L   + PF  CH  +DP  Y   C  D C   ++E   C A + YARAC+  G 
Sbjct: 259 FFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET-YCRAATEYARACSHAGY 315

Query: 546 MLWGWREH--VCNKDVGSCPNSQVFLYNLTTCQQTC---RSLSEADSHCLEGFAPVDGCG 600
            +  WR+    C      C +S V    ++ C  TC   +    ++ HCL      DGC 
Sbjct: 316 PIQDWRDDFPACTD---KCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCL------DGCY 366

Query: 601 CPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQ 652
           CPD   +D  G C+ L  C C   GL    G  + ++   CVC  G  +C +
Sbjct: 367 CPDGLVMDN-GTCISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTE 417



 Score =  122 bits (306), Expect = 5e-27
 Identities = 93/372 (25%), Positives = 156/372 (41%), Gaps = 27/372 (7%)

Query: 1938 DCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPR 1997
            D  C  WG  H+ TFDG+YY + GNC+Y+  ++       + V++ N         SC R
Sbjct: 61   DGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYR 120

Query: 1998 TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVL 2057
            ++ +    QE +    H      +++ N  ++ LP +  G    +   +Y++     G  
Sbjct: 121  SISLFFSNQEEIRIYGH------EIKKNGISLTLP-QTIGQIFIEKLADYILVKTTFGFS 173

Query: 2058 VSYNGLS-FSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDP 2116
            ++++G+S   ++L     G +  G CG   +  SDD I+   +   +    A+ W V  P
Sbjct: 174  LAWDGISGIYLKLSEDHKGKSC-GLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTP 232

Query: 2117 SKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDA 2176
                C  + S    P  +     +    K       CQ++    F  CH  + P  Y  +
Sbjct: 233  DDTKCVLTPSDFPNPCSSGMPAFEAIFFK-------CQILLQFPFLSCHEYIDPYLYIAS 285

Query: 2177 CVFDSCFMPGSSLECASLQAYAALCAQQNICL-DWRNHTHGACLVECPS---HREYQACG 2232
            CV D C        C +   YA  C+     + DWR+    AC  +C     HR+  +C 
Sbjct: 286  CVNDLCKTDDDETYCRAATEYARACSHAGYPIQDWRD-DFPACTDKCDDSFVHRDCISCC 344

Query: 2233 PAEEPTCK-SSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHF 2291
            P   PTC        +N   ++GC+CP+G +    G  + ++ C C G   +    G   
Sbjct: 345  P---PTCTFEKQCLGSNLHCLDGCYCPDGLV-MDNGTCISLENCPC-GFHGLAYSVGSKI 399

Query: 2292 EFDCKNCVCLEG 2303
            E +C  CVC+ G
Sbjct: 400  EQECTECVCVGG 411



 Score =  107 bits (267), Expect = 2e-22
 Identities = 87/354 (24%), Positives = 127/354 (35%), Gaps = 55/354 (15%)

Query: 2309 CQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSK 2368
            C  + C+ KPV  C  DG +L  ++N    CC    C C  +LC      C     +  +
Sbjct: 1903 CVCESCT-KPVPLC-HDGEFLTVDLNSTHFCCPQYYCVCEPNLCPMPLLNCAEDMNLVKE 1960

Query: 2369 MVPGRCCPF-----------------------------------YWCESKGVCVHGNAEY 2393
             V G+CCP                                    Y CE   VCV      
Sbjct: 1961 NVSGQCCPTWHCECNCENLVMPTCEVGEFTAIDHNFQSDCGCIQYLCEKDDVCVFQEVSV 2020

Query: 2394 -QPGSPVYS----SKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGE--C 2446
              PG  +        C    C ++ DN+T  + +  T V C+  C        +P +  C
Sbjct: 2021 LNPGQSMIKYLEEDFCYTIECLEEKDNHTGFHTLNFTLVNCSKKCDVHQVYTPSPSDYGC 2080

Query: 2447 CKKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDA 2506
            C  C+   C     +   V+   G   S    NCT + CVK     I     + CP F+ 
Sbjct: 2081 CGTCKNVSCKFHMENGTSVVYAVG---STWHYNCTTYECVKTDEGAIILNYTMVCPPFNE 2137

Query: 2507 SICI--PGSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGCTKTVLMN--HCSGSC 2562
            + C    G +     GCCK C  + E R+ C  V + + +    C     +N   C G C
Sbjct: 2138 TECKMNEGIVKLYNEGCCKIC--KREERI-CQKVIIKSVIRKQDCMSQSPINVASCDGKC 2194

Query: 2563 GTFVMYSAKAQALDHSCSCCKEEKTSQREVVLSCP-NGGSLTHTYTHIESCQCQ 2615
             +  +Y+   ++    C CC+E       V L C  NG  + +T      C CQ
Sbjct: 2195 PSATIYNINIESHLRFCKCCRENGVRNLSVPLYCSGNGTEIMYTLQEPIDCTCQ 2248



 Score = 95.5 bits (236), Expect = 6e-19
 Identities = 79/319 (24%), Positives = 149/319 (46%), Gaps = 33/319 (10%)

Query: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKE-FAVHLKRGPGQAEAP-AGVESI 94
           CS  G+ H+ TFDG  + F G+C Y      +G+ K+ F + L++ P +       ++SI
Sbjct: 424 CSVVGDSHFTTFDGRHYSFIGMCQYILV---KGTGKDKFTITLQKAPCEQNLGLVCLQSI 480

Query: 95  LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGL--LIE---KSDAYTKVYSRAGLTLMWNR 149
            L ++DD  +  +      G ++++P+    L  ++E    S  +  + +  GL +++  
Sbjct: 481 TLILEDD--FNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAI 538

Query: 150 E-DALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLF--SPLEFGNMQKINQPDVVC 206
           + + + ++L + ++  T GLCG +NG     +FLS   +   +P    N  +++     C
Sbjct: 539 DGERIYIQLTSAWKRRTLGLCGTFNG-NIRDDFLSPSGMIEGTPQLHANAWRVSS---TC 594

Query: 207 EDPEEEVAPASCSEHR------AECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGG 260
             P        C+ ++      A C+ ++  E FA C   +    Y + C+ D C+C  G
Sbjct: 595 FAPVHVPVVDPCNINQQNIGYAAHCD-VIHQELFAPCHIYISPGLYYQLCRHDACKC--G 651

Query: 261 DTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHL 320
            +C+C+ +A ++  C   G  P ++RT  S      +  C   ++Y    S C+ +C  L
Sbjct: 652 SSCLCNALAHYAYLCGQHGV-PIDFRTQISF----CAVVCQKGMLYHHCSSFCLHSCISL 706

Query: 321 EVSSLCEEHRMDGCFCPEG 339
                C +   +GC CPEG
Sbjct: 707 SSPEQCSDDCAEGCNCPEG 725



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 76/307 (24%), Positives = 121/307 (39%), Gaps = 33/307 (10%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C ++ C   CT +GD HY +FDGL Y Y  +C   L++    S  +  V   N  C  ND
Sbjct: 844  CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDS--DISVIAQNKKCFDND 901

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
             V     LI   +T+  L  T +           +Q+      K   +++++G   VV  
Sbjct: 902  IVCSKSVLISVGDTEIYLNDTPYKQ---------KQSGFFLENKSTYQLWKAGYYIVVYF 952

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 2111
            PE  + + ++  +        ++ N   G CG     TS+D    +   V N     D W
Sbjct: 953  PEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW 1012

Query: 2112 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--SPLCQLIKDSLFAQCHALVP 2169
             +     P        T +P            H++  P     C ++   +FA C  ++ 
Sbjct: 1013 ALGQCESP------DETIKPCEA---------HQNKFPYAKKECSILYSDIFASCRNVID 1057

Query: 2170 PQHYYDACVFDSCFMP-GSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLVECPSHR 2226
               +   C  D+C    G   EC   S+ AYA  C Q+ I + WR+ T   C ++C  + 
Sbjct: 1058 VTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSST--VCSLDCEYYN 1115

Query: 2227 EYQACGP 2233
            E    GP
Sbjct: 1116 EGLGEGP 1122



 Score = 85.9 bits (211), Expect = 5e-16
 Identities = 63/279 (22%), Positives = 129/279 (46%), Gaps = 50/279 (17%)

Query: 36   VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCR------GSYKEFAVHLKRGPGQAEAPA 89
            VC+ +G+ HY +FDG         +Y++ SDC+          + +V  +          
Sbjct: 852  VCTIYGDRHYYSFDG--------LEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV 903

Query: 90   GVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSP--GLLIEKSDAY---------TKVY 138
              +S+L+++ D  IYL             TP+     G  +E    Y            +
Sbjct: 904  CSKSVLISVGDTEIYLN-----------DTPYKQKQSGFFLENKSTYQLWKAGYYIVVYF 952

Query: 139  SRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGV-LFSPLEFGNMQ 197
                +T++W+R+  + +++  +++N   GLCG+++   S     S+ + + +   FG+  
Sbjct: 953  PEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW 1012

Query: 198  KINQPDVVCEDPEEEVAPASCSEHR-----AECERLLTAEAFADCQDLVPLEPYLRACQQ 252
             + Q    CE P+E + P    +++      EC  +L ++ FA C++++ +  + + C +
Sbjct: 1013 ALGQ----CESPDETIKPCEAHQNKFPYAKKECS-ILYSDIFASCRNVIDVTSFAKNCHE 1067

Query: 253  DRCRCP-GGD-TCVCSTVAEFSRQCSHAGGRPGNWRTAT 289
            D C C  GGD  C+C+++A ++ +C    G   +WR++T
Sbjct: 1068 DTCNCNLGGDCECLCTSIAAYAYKCCQE-GISIHWRSST 1105



 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 96/453 (21%), Positives = 155/453 (34%), Gaps = 70/453 (15%)

Query: 733  GAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYC 792
            G  ++V+ + C        C +  C   CS+      ITFDG         SY+ V+   
Sbjct: 1421 GRPVQVNSDIC--------CPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVR-IP 1471

Query: 793  GQNSSLGSFSIITENVPCGTTGVTCSKAI-------KIFMGRTELKLEDKHRVVIQRDEG 845
            G+              P G     C K +       KI + R   K+E    VV      
Sbjct: 1472 GEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSS 1531

Query: 846  HHVAYTTREVGQYLVVESSTGIIVIWDKRTTV------FIKLAPSYKGTVCGLCGNFDHR 899
              ++    + G   V+ +  G+I+ W   T +      F     SY   +CG+C   +  
Sbjct: 1532 QELSI--EDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGIC---NED 1586

Query: 900  SNNDFTTRDHMVVSSELDFG---NSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCS--- 953
             ++D   ++  ++++  D G    SW+   +       P         R+  E  CS   
Sbjct: 1587 PDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPV--------RNCTEHDCSQCI 1638

Query: 954  -ILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFW 1012
             +L   +F  CH KV P+ F   C     +     + EC   A+++Y   C K   C+ W
Sbjct: 1639 DLLNRRIFIPCHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQW 1693

Query: 1013 RTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDR 1072
            RTPD C + C        C     PC  R   TC           ++  E C   C    
Sbjct: 1694 RTPDYCSLSCPEGKEYQPC---VRPCEAR---TCLNQWFYGHTSCLNLREDCV--CKVGT 1745

Query: 1073 PIYEEDLKKCVTADKCGCYVEDTHYPPGASV----PTEETCKSCV-----------CTNS 1117
             ++     +C+   +C C   +        +      E T   C+           C   
Sbjct: 1746 ILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEE 1805

Query: 1118 SQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1150
               VC  E   ++        C  E+CG + T+
Sbjct: 1806 PTPVCEREAEVVMGIIDKWTCCSKEVCGCDTTL 1838



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 27/71 (38%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 1031 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1090
            CEW YEPC    F+TC     +     +  +EGC P CPK+  I +E   KCV    C  
Sbjct: 1277 CEWRYEPCATPCFKTCSDPEALACKF-LPPVEGCLPYCPKNM-ILDEVTLKCVYPRDCIP 1334

Query: 1091 YV--EDTHYPP 1099
             +  E T  PP
Sbjct: 1335 VIPTEPTLMPP 1345



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 59/276 (21%), Positives = 105/276 (38%), Gaps = 33/276 (11%)

Query: 358  VVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTL 417
            ++V +    V ++ + V LP  +   S+    S +++ + A  +     L  ++ +    
Sbjct: 1509 IIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGF 1568

Query: 418  DQASQGQVQGLCGNFNGLEGDDFKTASGLV----EATGAGFANTWKAQSSCHDKLDWLDD 473
                    +GLCG  N    DD +  +G +    E  G  F  +W+ + S          
Sbjct: 1569 RFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGL-FIESWEIEKSFE-------- 1619

Query: 474  PCSLNIESANYAEHWCS----LLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCL 529
              ++     N  EH CS    LL +    F  CH  V P ++ ++   +     N E   
Sbjct: 1620 -VTMRRPVRNCTEHDCSQCIDLLNR--RIFIPCHDKVSPEDFCEKMWINYTYFWNYE--- 1673

Query: 530  CAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQ-QTC-RSLSEADS 587
            C ALS+Y   C    + +       C+    SCP  + +   +  C+ +TC        +
Sbjct: 1674 CDALSAYVALCNKFDICIQWRTPDYCSL---SCPEGKEYQPCVRPCEARTCLNQWFYGHT 1730

Query: 588  HCLEGFAPVDGCGCPDHTFL--DEKGRCVPLAKCSC 621
             CL      + C C   T L      +C+P  +C+C
Sbjct: 1731 SCLN---LREDCVCKVGTILHRPHSAQCIPEKECAC 1763



 Score = 35.4 bits (80), Expect = 0.75
 Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 3/70 (4%)

Query: 1876 DPPRQENETW--WLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVR-VEDPDGCC 1932
            D PR   E W   + +C +  C  N ++  ++ +C+  P P C    + V  + D   CC
Sbjct: 1768 DQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCC 1827

Query: 1933 WHWECDCYCT 1942
                C C  T
Sbjct: 1828 SKEVCGCDTT 1837



 Score = 34.3 bits (77), Expect = 1.7
 Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 16/145 (11%)

Query: 112  LNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFR----NHTCG 167
            ++  VV  P  S  L IE S +   + + AGL + W+    + +++   FR    ++T G
Sbjct: 1520 VDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGI-IDIHFGFRFNLSSYTEG 1578

Query: 168  LCGDYNGLQSYSEFLSDGVLFSPLE----FGNMQKINQP-DVVCEDPEEEVAPASCSEHR 222
            LCG  N        + +G + + +E    F    +I +  +V    P       +C+EH 
Sbjct: 1579 LCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVR-----NCTEHD 1633

Query: 223  -AECERLLTAEAFADCQDLVPLEPY 246
             ++C  LL    F  C D V  E +
Sbjct: 1634 CSQCIDLLNRRIFIPCHDKVSPEDF 1658



 Score = 34.3 bits (77), Expect = 1.7
 Identities = 25/101 (24%), Positives = 40/101 (39%), Gaps = 13/101 (12%)

Query: 1867 TKP-PECPDFDPPRQE-NETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVR 1924
            TKP P C D +    + N T + C  +   C+ N           P P+  C+  +  V+
Sbjct: 1909 TKPVPLCHDGEFLTVDLNSTHFCCPQYYCVCEPNLC---------PMPLLNCAEDMNLVK 1959

Query: 1925 VEDPDGCCWHWECDCYCTGWGDP--HYVTFDGLYYSYQGNC 1963
                  CC  W C+C C     P      F  + +++Q +C
Sbjct: 1960 ENVSGQCCPTWHCECNCENLVMPTCEVGEFTAIDHNFQSDC 2000



 Score = 32.3 bits (72), Expect = 6.4
 Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 16/78 (20%)

Query: 1870 PECPDFDPPRQENETW--------WLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQ 1921
            P+C +   P  E E          W C C    C  + T+      CE   +PTC+N  +
Sbjct: 1800 PDCDEEPTPVCEREAEVVMGIIDKWTC-CSKEVCGCDTTL------CETS-IPTCTNSQK 1851

Query: 1922 PVRVEDPDGCCWHWECDC 1939
             +    P  CC  ++C+C
Sbjct: 1852 LIVGHSPLSCCPQYKCEC 1869


>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
          Length = 2250

 Score =  337 bits (864), Expect = 9e-92
 Identities = 197/652 (30%), Positives = 322/652 (49%), Gaps = 70/652 (10%)

Query: 389  SSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVE 448
            SS  I++    G+++   +    ++++ L  A + +  GLCG FNG   DDF + SG++E
Sbjct: 520  SSLFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIE 578

Query: 449  ATGAGFANTWKAQSSCHDKLDW-LDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVD 507
             T    AN W+  S+C   +   + DPC++N ++  YA H C ++   +  F  CH  + 
Sbjct: 579  GTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAH-CDVIH--QELFAPCHIYIS 635

Query: 508  PAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQV 567
            P  YY+ C++D C C ++  CLC AL+ YA  C   GV +  +R  +    V  C    +
Sbjct: 636  PGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGVPI-DFRTQISFCAV-VCQKGML 691

Query: 568  FLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEK-GRCVPLAKCSCYHRGL 626
            + +  + C  +C SLS  +  C +  A  +GC CP+  F ++    CVP+  C C++RG 
Sbjct: 692  YHHCSSFCLHSCISLSSPEQ-CSDDCA--EGCNCPEGKFYEDTLNFCVPIFHCRCHYRGS 748

Query: 627  YLEAGDVVVRQEERCVCRDGRLHCRQIRLIG--QSCTAPKIHMDCS--NLTALATSKPRA 682
              + G+++      C C +G + C ++        C   K + DC   +    A      
Sbjct: 749  VYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCE 808

Query: 683  LSCQTLAAGYYHTE---CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD 739
             +C  LA  +  T    C+SGCVC  G+                                
Sbjct: 809  TTCANLAMNFTCTPSSPCISGCVCAPGV-------------------------------- 836

Query: 740  CNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLG 799
                 C+RG + CT   C   C+IYG  HY +FDG  YD+   C    ++     ++   
Sbjct: 837  -----CRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIK-----SADDS 886

Query: 800  SFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHV----AYTTREV 855
              S+I +N  C    + CSK++ I +G TE+ L D      Q+  G  +     Y   + 
Sbjct: 887  DISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYK--QKQSGFFLENKSTYQLWKA 944

Query: 856  GQYLVVE-SSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSS 914
            G Y+VV      I ++WD++TT+ IK+ P +K  + GLCGNFD  ++ND TT +++ V +
Sbjct: 945  GYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRN 1004

Query: 915  ELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYE 974
               FG+SW     C       +PC  + ++  +A+K+CSIL S +F+ C + +D   F +
Sbjct: 1005 ARVFGDSWALGQ-CESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAK 1063

Query: 975  ACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYN 1026
             C  D+C+C+ GGDCEC C+++A+YA +C +EG  + WR+  +C + C+YYN
Sbjct: 1064 NCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCEYYN 1115



 Score =  202 bits (513), Expect = 5e-51
 Identities = 118/433 (27%), Positives = 207/433 (47%), Gaps = 35/433 (8%)

Query: 697  CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAV 756
            C+ GC CPDGL+ D  G C+  + CPC  +   YS G+KI+ +C  C C  G W CT+  
Sbjct: 361  CLDGCYCPDGLVMDN-GTCISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQD 419

Query: 757  CHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPC-GTTGV 815
            C   CS+ G  H+ TFDG++Y F G C Y+ V     + +    F+I  +  PC    G+
Sbjct: 420  CPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV-----KGTGKDKFTITLQKAPCEQNLGL 474

Query: 816  TCSKAIKIFMG---RTELKLEDKHRVVIQRDEGHH---VAYTTREVGQYLVVESSTGIIV 869
             C ++I + +      ++ L    +++   ++G +   +         +++++++ G+ +
Sbjct: 475  VCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKI 534

Query: 870  IWD-KRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTC 928
            ++      ++I+L  ++K    GLCG F+    +DF +   M+  +     N+W+ + TC
Sbjct: 535  LFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTC 594

Query: 929  --PDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTG 986
              P      +PC++N     +A   C ++   +F+ CH  + P  +Y+ C HD+C C + 
Sbjct: 595  FAPVHVPVVDPCNINQQNIGYA-AHCDVIHQELFAPCHIYISPGLYYQLCRHDACKCGS- 652

Query: 987  GDCECFCSAVASYAQECTKEGACVFWRTP-DLCPIFCDYYNPPHECEWHYEPCGNRSFET 1045
                C C+A+A YA  C + G  + +RT    C + C       +    Y  C +    +
Sbjct: 653  ---SCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVC-------QKGMLYHHCSSFCLHS 702

Query: 1046 CRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPT 1105
            C +++      S    EGC   CP+ +  YE+ L  CV    C C+   + Y PG  +PT
Sbjct: 703  CISLSS-PEQCSDDCAEGC--NCPEGK-FYEDTLNFCVPIFHCRCHYRGSVYQPGELIPT 758

Query: 1106 EETCKSCVCTNSS 1118
                  C C+N +
Sbjct: 759  PSGL--CQCSNGT 769



 Score =  172 bits (435), Expect = 5e-42
 Identities = 131/485 (27%), Positives = 214/485 (44%), Gaps = 46/485 (9%)

Query: 1913 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 1972
            MP C    +PV+V   D CC  WEC C C+   +   +TFDG   +     +Y+LV  I 
Sbjct: 1414 MPDCGFRGRPVQVNS-DICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILV-RIP 1471

Query: 1973 PSVDNFGVYIDNYHCDPNDKVS--CPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVA 2030
              +    +   + +  P+ ++S  C + L V     ++++       +  +V+V+   V 
Sbjct: 1472 GEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNR-----LARKVEVDSIVVP 1526

Query: 2031 LPYKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRLPY---HRFGNNTKGQCGTCTN 2087
            LP+    L +  SG  YV+  P  G+++ ++ L+  + + +       + T+G CG C  
Sbjct: 1527 LPFSSQELSIEDSGSMYVITTP-AGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNE 1585

Query: 2088 TTSDDCILPSGEIVSNCEAAA---DQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPH 2144
               DD  + +G I++N E      + W +    +        T +RP        +    
Sbjct: 1586 DPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFE-------VTMRRPV-------RNCTE 1631

Query: 2145 KDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQ 2204
             DC  S    L+   +F  CH  V P+ + +    +  +    + EC +L AY ALC + 
Sbjct: 1632 HDC--SQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYF--WNYECDALSAYVALCNKF 1687

Query: 2205 NICLDWRNHTHGACLVECPSHREYQAC-GPAEEPTCKSSSSQQNNTV--LVEGCFCPEGT 2261
            +IC+ WR  T   C + CP  +EYQ C  P E  TC +     + +   L E C C  GT
Sbjct: 1688 DICIQWR--TPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGT 1745

Query: 2262 MNYAPGFDVCV--KTCGCVGPDNVPREFGEHFEFDCKNCV---CLEGGSGIICQPKRCSQ 2316
            + + P    C+  K C C   ++ PR  GE +      C    CLE GS I  +P  C +
Sbjct: 1746 ILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPD-CDE 1804

Query: 2317 KPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCP 2376
            +P   C  +   +   ++   TCC+  VC C+T+LC+     C    ++     P  CCP
Sbjct: 1805 EPTPVCEREAEVVMGIIDKW-TCCSKEVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCP 1863

Query: 2377 FYWCE 2381
             Y CE
Sbjct: 1864 QYKCE 1868



 Score =  134 bits (338), Expect = 9e-31
 Identities = 103/373 (27%), Positives = 162/373 (43%), Gaps = 43/373 (11%)

Query: 759  GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVP-CGTTGVTC 817
            G C  +G  H+ TFDG YY F G+CSY+  +D CG       +++   N P C  +  +C
Sbjct: 62   GICKTWGQYHFETFDGIYYYFPGNCSYIFAKD-CGDLEP--RYTVWVHNSPKCLGSVYSC 118

Query: 818  SKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTRE-VGQ--------YLVVESSTGII 868
             ++I +F    E     + R+     + + ++ T  + +GQ        Y++V+++ G  
Sbjct: 119  YRSISLFFSNQE-----EIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFS 173

Query: 869  VIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK----- 923
            + WD  + +++KL+  +KG  CGLCGN++   ++DF             F NSW      
Sbjct: 174  LAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPD 233

Query: 924  EAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSC 983
            +       S  P PCS           +C IL    F  CH  +DP  +  +CV+D C  
Sbjct: 234  DTKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKT 293

Query: 984  DTGGDCECFCSAVASYAQECTKEGACV-FWRTP-DLCPIFCDYYNPPHECEWHYEPCGNR 1041
            D   D E +C A   YA+ C+  G  +  WR     C   CD      +C     P    
Sbjct: 294  D---DDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPP--TC 348

Query: 1042 SFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGA 1101
            +FE     + +H       L+GCY  CP    +   D   C++ + C C      Y  G+
Sbjct: 349  TFEKQCLGSNLHC------LDGCY--CPDGLVM---DNGTCISLENCPCGFHGLAYSVGS 397

Query: 1102 SVPTEETCKSCVC 1114
             +  E+ C  CVC
Sbjct: 398  KI--EQECTECVC 408



 Score =  134 bits (337), Expect = 1e-30
 Identities = 93/337 (27%), Positives = 140/337 (41%), Gaps = 22/337 (6%)

Query: 20  GSELQTEGRTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLK 79
           G+  Q      N    +C TWG +H++TFDG  + FPG C Y FA DC      + V + 
Sbjct: 47  GTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVH 106

Query: 80  RGPGQAEAPAGVESILLTI-----KDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAY 134
             P   +    V S   +I       + I +  H    NG  ++ P     + IEK   Y
Sbjct: 107 NSP---KCLGSVYSCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADY 163

Query: 135 TKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEF--LSDGVLFSPLE 192
             V +  G +L W+    + L+L    +  +CGLCG+YN +QS  +F  L +        
Sbjct: 164 ILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQS-DDFIILQEDYTEDIAM 222

Query: 193 FGNMQKINQPDVVCEDPEEEVAPASCSEHRAECE------RLLTAEAFADCQDLVPLEPY 246
           F N   +  PD           P  CS      E      ++L    F  C + +    Y
Sbjct: 223 FANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLY 282

Query: 247 LRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVY 306
           + +C  D C+    +T  C    E++R CSHAG    +WR       P  +  C  + V+
Sbjct: 283 IASCVNDLCKTDDDET-YCRAATEYARACSHAGYPIQDWRDD----FPACTDKCDDSFVH 337

Query: 307 LESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGAQAD 343
            +  S C  TC+  +       H +DGC+CP+G   D
Sbjct: 338 RDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMD 374



 Score =  128 bits (321), Expect = 9e-29
 Identities = 135/518 (26%), Positives = 185/518 (35%), Gaps = 93/518 (17%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C   +C   C+  GD H+ TFDG +YS+ G C Y+LV+      D F + +    C+ N 
Sbjct: 415  CTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK--GTGKDKFTITLQKAPCEQNL 472

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
             + C +++ +  E                QV + R    L     G       +N +V+I
Sbjct: 473  GLVCLQSITLILEDD-----------FNKQVTLGRGGQILTSPNQGF-----NLNGIVEI 516

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFG------------NNTKGQCGTCTNTTSDDCILPSGE 2099
              L  L      +F +++ +   G              T G CGT      DD + PSG 
Sbjct: 517  QTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGM 576

Query: 2100 IVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDS 2159
            I    +  A+ W V           SST   P             ++   +  C +I   
Sbjct: 577  IEGTPQLHANAWRV-----------SSTCFAPVHVPVVDPCNINQQNIGYAAHCDVIHQE 625

Query: 2160 LFAQCHALVPPQHYYDACVFDSCFMPGSSLECASLQAYAALCAQQNICLDWRNHTHGACL 2219
            LFA CH  + P  YY  C  D+C   GSS  C +L  YA LC Q  + +D+R      C 
Sbjct: 626  LFAPCHIYISPGLYYQLCRHDAC-KCGSSCLCNALAHYAYLCGQHGVPIDFRTQI-SFCA 683

Query: 2220 VECPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCV 2278
            V C     Y  C      +C S SS +Q +    EGC CPEG   Y    + CV      
Sbjct: 684  VVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKF-YEDTLNFCVPIF--- 739

Query: 2279 GPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADT 2338
                              +C C   GS  + QP      P   C                
Sbjct: 740  ------------------HCRCHYRGS--VYQPGELIPTPSGLC---------------Q 764

Query: 2339 CCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPF--YWCESKGVCVHGNAEYQPG 2396
            C N TV KC+         +CP G E      P    P     CE+    +  N    P 
Sbjct: 765  CSNGTV-KCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPS 823

Query: 2397 SPVYSSKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCS 2434
            SP  S     CVC   V    + N   CT+ PC   C+
Sbjct: 824  SPCISG----CVCAPGVCRRGMFN---CTYYPCPAVCT 854



 Score =  122 bits (306), Expect = 5e-27
 Identities = 103/412 (25%), Positives = 161/412 (39%), Gaps = 42/412 (10%)

Query: 257 CPGGDTCVCSTVAEFSRQC----SHAGGRPG---NWRTATSAVSPGASKTCPGNLVYLES 309
           C    TC C        +C    +   GR G    W         G     PGN  Y+ +
Sbjct: 32  CSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFA 91

Query: 310 GSPCMDTCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSDGSVLL 369
                  C  LE       H    C    G+     +++ L    ++ + ++  +  +  
Sbjct: 92  KD-----CGDLEPRYTVWVHNSPKCL---GSVYSCYRSISLFFSNQEEIRIYGHE--IKK 141

Query: 370 NELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLC 429
           N + + LP       + + + Y I+V    G  L      +  +++ L +  +G+  GLC
Sbjct: 142 NGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWD--GISGIYLKLSEDHKGKSCGLC 198

Query: 430 GNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKL----DWLDDPCSLNIESANYA 485
           GN+N ++ DDF           A FAN+W  Q+    K         +PCS  + +    
Sbjct: 199 GNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAI 258

Query: 486 EHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGV 545
              C +L   + PF  CH  +DP  Y   C  D C   ++E   C A + YARAC+  G 
Sbjct: 259 FFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET-YCRAATEYARACSHAGY 315

Query: 546 MLWGWREH--VCNKDVGSCPNSQVFLYNLTTCQQTC---RSLSEADSHCLEGFAPVDGCG 600
            +  WR+    C      C +S V    ++ C  TC   +    ++ HCL      DGC 
Sbjct: 316 PIQDWRDDFPACTD---KCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCL------DGCY 366

Query: 601 CPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQ 652
           CPD   +D  G C+ L  C C   GL    G  + ++   CVC  G  +C +
Sbjct: 367 CPDGLVMDN-GTCISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTE 417



 Score =  122 bits (306), Expect = 5e-27
 Identities = 93/372 (25%), Positives = 156/372 (41%), Gaps = 27/372 (7%)

Query: 1938 DCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPR 1997
            D  C  WG  H+ TFDG+YY + GNC+Y+  ++       + V++ N         SC R
Sbjct: 61   DGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYR 120

Query: 1998 TLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVL 2057
            ++ +    QE +    H      +++ N  ++ LP +  G    +   +Y++     G  
Sbjct: 121  SISLFFSNQEEIRIYGH------EIKKNGISLTLP-QTIGQIFIEKLADYILVKTTFGFS 173

Query: 2058 VSYNGLS-FSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDP 2116
            ++++G+S   ++L     G +  G CG   +  SDD I+   +   +    A+ W V  P
Sbjct: 174  LAWDGISGIYLKLSEDHKGKSC-GLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTP 232

Query: 2117 SKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDA 2176
                C  + S    P  +     +    K       CQ++    F  CH  + P  Y  +
Sbjct: 233  DDTKCVLTPSDFPNPCSSGMPAFEAIFFK-------CQILLQFPFLSCHEYIDPYLYIAS 285

Query: 2177 CVFDSCFMPGSSLECASLQAYAALCAQQNICL-DWRNHTHGACLVECPS---HREYQACG 2232
            CV D C        C +   YA  C+     + DWR+    AC  +C     HR+  +C 
Sbjct: 286  CVNDLCKTDDDETYCRAATEYARACSHAGYPIQDWRD-DFPACTDKCDDSFVHRDCISCC 344

Query: 2233 PAEEPTCK-SSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHF 2291
            P   PTC        +N   ++GC+CP+G +    G  + ++ C C G   +    G   
Sbjct: 345  P---PTCTFEKQCLGSNLHCLDGCYCPDGLV-MDNGTCISLENCPC-GFHGLAYSVGSKI 399

Query: 2292 EFDCKNCVCLEG 2303
            E +C  CVC+ G
Sbjct: 400  EQECTECVCVGG 411



 Score =  107 bits (266), Expect = 2e-22
 Identities = 87/354 (24%), Positives = 127/354 (35%), Gaps = 55/354 (15%)

Query: 2309 CQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSK 2368
            C  + C+ KPV  C  DG +L  ++N    CC    C C  +LC      C     +  +
Sbjct: 1903 CVCESCT-KPVPLC-HDGEFLTVDLNSTHFCCPQYYCVCEPNLCPMPLLNCAEDMNLVKE 1960

Query: 2369 MVPGRCCPF-----------------------------------YWCESKGVCVHGNAEY 2393
             V G+CCP                                    Y CE   VCV      
Sbjct: 1961 NVSGQCCPTWHCECNCENLIMPTCEVGEFTAIDHNFQSDCGCIQYLCEKDDVCVFQEVSV 2020

Query: 2394 -QPGSPVYS----SKCQDCVCTDKVDNNTLLNVIACTHVPCNTSCSPGFELMEAPGE--C 2446
              PG  +        C    C ++ DN+T  + +  T V C+  C        +P +  C
Sbjct: 2021 LNPGQSMIKYLEEDFCYAIECLEEKDNHTGFHTLNFTLVNCSKKCDVHQVYTPSPSDYGC 2080

Query: 2447 CKKCEQTHCIIKRPDNQHVILKPGDFKSDPKNNCTFFSCVKIHNQLISSVSNITCPNFDA 2506
            C  C+   C     +   V+   G   S    NCT + CVK     I     + CP F+ 
Sbjct: 2081 CGTCKNVSCKFHMENGTSVVYAVG---STWHYNCTTYECVKTDEGAIILNYTMVCPPFNE 2137

Query: 2507 SICI--PGSITFMPNGCCKTCTPRNETRVPCSTVPVTTEVSYAGCTKTVLMN--HCSGSC 2562
            + C    G +     GCCK C  + E R+ C  V + + +    C     +N   C G C
Sbjct: 2138 TECKMNEGIVKLYNEGCCKIC--KREERI-CQKVIIKSVIRKQDCMSQSPINVASCDGKC 2194

Query: 2563 GTFVMYSAKAQALDHSCSCCKEEKTSQREVVLSCP-NGGSLTHTYTHIESCQCQ 2615
             +  +Y+   ++    C CC+E       V L C  NG  + +T      C CQ
Sbjct: 2195 PSATIYNINIESHLRFCKCCRENGVRNLSVPLYCSGNGTEIMYTLQEPIDCTCQ 2248



 Score = 95.5 bits (236), Expect = 6e-19
 Identities = 79/319 (24%), Positives = 149/319 (46%), Gaps = 33/319 (10%)

Query: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKE-FAVHLKRGPGQAEAP-AGVESI 94
           CS  G+ H+ TFDG  + F G+C Y      +G+ K+ F + L++ P +       ++SI
Sbjct: 424 CSVVGDSHFTTFDGRHYSFIGMCQYILV---KGTGKDKFTITLQKAPCEQNLGLVCLQSI 480

Query: 95  LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGL--LIE---KSDAYTKVYSRAGLTLMWNR 149
            L ++DD  +  +      G ++++P+    L  ++E    S  +  + +  GL +++  
Sbjct: 481 TLILEDD--FNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAI 538

Query: 150 E-DALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLF--SPLEFGNMQKINQPDVVC 206
           + + + ++L + ++  T GLCG +NG     +FLS   +   +P    N  +++     C
Sbjct: 539 DGERIYIQLTSAWKRRTLGLCGTFNG-NIRDDFLSPSGMIEGTPQLHANAWRVSS---TC 594

Query: 207 EDPEEEVAPASCSEHR------AECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGG 260
             P        C+ ++      A C+ ++  E FA C   +    Y + C+ D C+C  G
Sbjct: 595 FAPVHVPVVDPCNINQQNIGYAAHCD-VIHQELFAPCHIYISPGLYYQLCRHDACKC--G 651

Query: 261 DTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHL 320
            +C+C+ +A ++  C   G  P ++RT  S      +  C   ++Y    S C+ +C  L
Sbjct: 652 SSCLCNALAHYAYLCGQHGV-PIDFRTQISF----CAVVCQKGMLYHHCSSFCLHSCISL 706

Query: 321 EVSSLCEEHRMDGCFCPEG 339
                C +   +GC CPEG
Sbjct: 707 SSPEQCSDDCAEGCNCPEG 725



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 76/307 (24%), Positives = 121/307 (39%), Gaps = 33/307 (10%)

Query: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991
            C ++ C   CT +GD HY +FDGL Y Y  +C   L++    S  +  V   N  C  ND
Sbjct: 844  CTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDS--DISVIAQNKKCFDND 901

Query: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051
             V     LI   +T+  L  T +           +Q+      K   +++++G   VV  
Sbjct: 902  IVCSKSVLISVGDTEIYLNDTPYKQ---------KQSGFFLENKSTYQLWKAGYYIVVYF 952

Query: 2052 PELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQW 2111
            PE  + + ++  +        ++ N   G CG     TS+D    +   V N     D W
Sbjct: 953  PEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW 1012

Query: 2112 LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--SPLCQLIKDSLFAQCHALVP 2169
             +     P        T +P            H++  P     C ++   +FA C  ++ 
Sbjct: 1013 ALGQCESP------DETIKPCEA---------HQNKFPYAKKECSILYSDIFASCRNVID 1057

Query: 2170 PQHYYDACVFDSCFMP-GSSLEC--ASLQAYAALCAQQNICLDWRNHTHGACLVECPSHR 2226
               +   C  D+C    G   EC   S+ AYA  C Q+ I + WR+ T   C ++C  + 
Sbjct: 1058 VTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSST--VCSLDCEYYN 1115

Query: 2227 EYQACGP 2233
            E    GP
Sbjct: 1116 EGLGEGP 1122



 Score = 85.9 bits (211), Expect = 5e-16
 Identities = 63/279 (22%), Positives = 129/279 (46%), Gaps = 50/279 (17%)

Query: 36   VCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCR------GSYKEFAVHLKRGPGQAEAPA 89
            VC+ +G+ HY +FDG         +Y++ SDC+          + +V  +          
Sbjct: 852  VCTIYGDRHYYSFDG--------LEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIV 903

Query: 90   GVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSP--GLLIEKSDAY---------TKVY 138
              +S+L+++ D  IYL             TP+     G  +E    Y            +
Sbjct: 904  CSKSVLISVGDTEIYLN-----------DTPYKQKQSGFFLENKSTYQLWKAGYYIVVYF 952

Query: 139  SRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGV-LFSPLEFGNMQ 197
                +T++W+R+  + +++  +++N   GLCG+++   S     S+ + + +   FG+  
Sbjct: 953  PEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW 1012

Query: 198  KINQPDVVCEDPEEEVAPASCSEHR-----AECERLLTAEAFADCQDLVPLEPYLRACQQ 252
             + Q    CE P+E + P    +++      EC  +L ++ FA C++++ +  + + C +
Sbjct: 1013 ALGQ----CESPDETIKPCEAHQNKFPYAKKECS-ILYSDIFASCRNVIDVTSFAKNCHE 1067

Query: 253  DRCRCP-GGD-TCVCSTVAEFSRQCSHAGGRPGNWRTAT 289
            D C C  GGD  C+C+++A ++ +C    G   +WR++T
Sbjct: 1068 DTCNCNLGGDCECLCTSIAAYAYKCCQE-GISIHWRSST 1105



 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 96/453 (21%), Positives = 155/453 (34%), Gaps = 70/453 (15%)

Query: 733  GAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYC 792
            G  ++V+ + C        C +  C   CS+      ITFDG         SY+ V+   
Sbjct: 1421 GRPVQVNSDIC--------CPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVR-IP 1471

Query: 793  GQNSSLGSFSIITENVPCGTTGVTCSKAI-------KIFMGRTELKLEDKHRVVIQRDEG 845
            G+              P G     C K +       KI + R   K+E    VV      
Sbjct: 1472 GEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSS 1531

Query: 846  HHVAYTTREVGQYLVVESSTGIIVIWDKRTTV------FIKLAPSYKGTVCGLCGNFDHR 899
              ++    + G   V+ +  G+I+ W   T +      F     SY   +CG+C   +  
Sbjct: 1532 QELSI--EDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGIC---NED 1586

Query: 900  SNNDFTTRDHMVVSSELDFG---NSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCS--- 953
             ++D   ++  ++++  D G    SW+   +       P         R+  E  CS   
Sbjct: 1587 PDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPV--------RNCTEHDCSQCI 1638

Query: 954  -ILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVFW 1012
             +L   +F  CH KV P+ F   C     +     + EC   A+++Y   C K   C+ W
Sbjct: 1639 DLLNRRIFIPCHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQW 1693

Query: 1013 RTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDR 1072
            RTPD C + C        C     PC  R   TC           ++  E C   C    
Sbjct: 1694 RTPDYCSLSCPEGKEYQPC---VRPCEAR---TCLNQWFYGHTSCLNLREDCV--CKVGT 1745

Query: 1073 PIYEEDLKKCVTADKCGCYVEDTHYPPGASV----PTEETCKSCV-----------CTNS 1117
             ++     +C+   +C C   +        +      E T   C+           C   
Sbjct: 1746 ILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEE 1805

Query: 1118 SQVVCRPEEGKILNQTQDGAFCYWEICGPNGTV 1150
               VC  E   ++        C  E+CG + T+
Sbjct: 1806 PTPVCEREAEVVMGIIDKWTCCSKEVCGCDTTL 1838



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 27/71 (38%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 1031 CEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGC 1090
            CEW YEPC    F+TC     +     +  +EGC P CPK+  I +E   KCV    C  
Sbjct: 1277 CEWRYEPCATPCFKTCSDPEALACKF-LPPVEGCLPYCPKNM-ILDEVTLKCVYPRDCIP 1334

Query: 1091 YV--EDTHYPP 1099
             +  E T  PP
Sbjct: 1335 VIPTEPTLMPP 1345



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 59/276 (21%), Positives = 105/276 (38%), Gaps = 33/276 (11%)

Query: 358  VVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTL 417
            ++V +    V ++ + V LP  +   S+    S +++ + A  +     L  ++ +    
Sbjct: 1509 IIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGF 1568

Query: 418  DQASQGQVQGLCGNFNGLEGDDFKTASGLV----EATGAGFANTWKAQSSCHDKLDWLDD 473
                    +GLCG  N    DD +  +G +    E  G  F  +W+ + S          
Sbjct: 1569 RFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGL-FIESWEIEKSFE-------- 1619

Query: 474  PCSLNIESANYAEHWCS----LLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCL 529
              ++     N  EH CS    LL +    F  CH  V P ++ ++   +     N E   
Sbjct: 1620 -VTMRRPVRNCTEHDCSQCIDLLNR--RIFIPCHDKVSPEDFCEKMWINYTYFWNYE--- 1673

Query: 530  CAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQ-QTC-RSLSEADS 587
            C ALS+Y   C    + +       C+    SCP  + +   +  C+ +TC        +
Sbjct: 1674 CDALSAYVALCNKFDICIQWRTPDYCSL---SCPEGKEYQPCVRPCEARTCLNQWFYGHT 1730

Query: 588  HCLEGFAPVDGCGCPDHTFL--DEKGRCVPLAKCSC 621
             CL      + C C   T L      +C+P  +C+C
Sbjct: 1731 SCLN---LREDCVCKVGTILHRPHSAQCIPEKECAC 1763



 Score = 35.4 bits (80), Expect = 0.75
 Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 3/70 (4%)

Query: 1876 DPPRQENETW--WLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVR-VEDPDGCC 1932
            D PR   E W   + +C +  C  N ++  ++ +C+  P P C    + V  + D   CC
Sbjct: 1768 DQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCC 1827

Query: 1933 WHWECDCYCT 1942
                C C  T
Sbjct: 1828 SKEVCGCDTT 1837



 Score = 34.3 bits (77), Expect = 1.7
 Identities = 37/145 (25%), Positives = 63/145 (43%), Gaps = 16/145 (11%)

Query: 112  LNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFR----NHTCG 167
            ++  VV  P  S  L IE S +   + + AGL + W+    + +++   FR    ++T G
Sbjct: 1520 VDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGI-IDIHFGFRFNLSSYTEG 1578

Query: 168  LCGDYNGLQSYSEFLSDGVLFSPLE----FGNMQKINQP-DVVCEDPEEEVAPASCSEHR 222
            LCG  N        + +G + + +E    F    +I +  +V    P       +C+EH 
Sbjct: 1579 LCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVR-----NCTEHD 1633

Query: 223  -AECERLLTAEAFADCQDLVPLEPY 246
             ++C  LL    F  C D V  E +
Sbjct: 1634 CSQCIDLLNRRIFIPCHDKVSPEDF 1658



 Score = 33.9 bits (76), Expect = 2.2
 Identities = 25/101 (24%), Positives = 40/101 (39%), Gaps = 13/101 (12%)

Query: 1867 TKP-PECPDFDPPRQE-NETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVR 1924
            TKP P C D +    + N T + C  +   C+ N           P P+  C+  +  V+
Sbjct: 1909 TKPVPLCHDGEFLTVDLNSTHFCCPQYYCVCEPNLC---------PMPLLNCAEDMNLVK 1959

Query: 1925 VEDPDGCCWHWECDCYCTGWGDP--HYVTFDGLYYSYQGNC 1963
                  CC  W C+C C     P      F  + +++Q +C
Sbjct: 1960 ENVSGQCCPTWHCECNCENLIMPTCEVGEFTAIDHNFQSDC 2000



 Score = 32.3 bits (72), Expect = 6.4
 Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 16/78 (20%)

Query: 1870 PECPDFDPPRQENETW--------WLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQ 1921
            P+C +   P  E E          W C C    C  + T+      CE   +PTC+N  +
Sbjct: 1800 PDCDEEPTPVCEREAEVVMGIIDKWTC-CSKEVCGCDTTL------CETS-IPTCTNSQK 1851

Query: 1922 PVRVEDPDGCCWHWECDC 1939
             +    P  CC  ++C+C
Sbjct: 1852 LIVGHSPLSCCPQYKCEC 1869


>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
          Length = 1950

 Score =  291 bits (745), Expect = 6e-78
 Identities = 236/883 (26%), Positives = 360/883 (40%), Gaps = 134/883 (15%)

Query: 698  VSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVC 757
            V GC CPD +  +  G CV++ +C C  N+++   G  I  D N C C+ G  +C     
Sbjct: 1130 VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDDNKCVCRDGILLCQ---- 1185

Query: 758  HGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTC 817
                        I  D    +  G   YV   D   Q  +  + S  T N+P        
Sbjct: 1186 ------------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS--TRNIPV------- 1224

Query: 818  SKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTV 877
                           +D               Y   E G + ++  S   +   +   T 
Sbjct: 1225 --------------FDD---------------YCGHENGTFRILTES---VPCCEDGLTC 1252

Query: 878  FIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEP 937
              K+  +++G VCGLCGN +    +DFTTR   V S  L+FGNSWK +  C D      P
Sbjct: 1253 SRKIIVAFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFP 1312

Query: 938  CSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVA 997
            C  NP+ ++WA ++C IL+ S F  CH+KVDP  +++ C+ ++C+CD  G    FC+AVA
Sbjct: 1313 CDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVA 1372

Query: 998  SYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNIS 1057
             YA+ C+  G CV WR P+LCP++CDYYN P EC WHYEPCG  + +TC+  + +     
Sbjct: 1373 MYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCK--DQLVGQKF 1430

Query: 1058 VSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETC-KSCVCTN 1116
             S LEGCY +CP   P  +E+  KCV+  +C C+  D   P G  +  E+ C ++C C  
Sbjct: 1431 SSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDV-IPAGGVI--EDNCGRTCYCI- 1486

Query: 1117 SSQVVCRPEEGKILNQTQDGAFCYWEICGPNGT--VEKHFNICSITTRPSTLTTFTTITL 1174
            + Q+ C   E    N T       + +     T  +     I  +T  PST  +   IT 
Sbjct: 1487 AGQLEC--SETAPTNST-------FAVSTTTATTILSTGAAITLVTGGPSTAASIPAITT 1537

Query: 1175 PTTPTTFTTT-------TTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETF 1227
             ++ TT TT        TT  T TS  ++ST+       +       P+     G   T 
Sbjct: 1538 SSSETTGTTLGPLTEPFTTGITETSVPIISTSGN-----AGMTGVVSPTVTGASGMAGTT 1592

Query: 1228 DGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQKPGGVIPMAFCLNY 1287
             GV  A       +        E+ G         +VG      +  PG  +      + 
Sbjct: 1593 GGVDAATTGAASENTS------ERAGTPRVSGATPAVGGGSTPGEAGPGATV------SG 1640

Query: 1288 EINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTP 1347
               V        P    T++  + +    TT  +V      TS+++T+   ++  T  + 
Sbjct: 1641 STGVSAGSITASPGASATSSESSKSG---TTGPSVGGKTGATSSEATSSEGMSGVTGQS- 1696

Query: 1348 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-----------TTTPITTTTTVTPTPT 1396
                 G+   + + IT  T+ T +  P     P           TT      TT      
Sbjct: 1697 ----LGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGEN 1752

Query: 1397 PTGTQTPTSTPITTTTTV----TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPT 1452
             +G    T   +  TT+     T   + TG   P  T ++ T  V+P  TP    + TP 
Sbjct: 1753 TSGALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPG 1812

Query: 1453 AITTTSTVTPTPTPTGTQTPTT--------TPITTTTTVTPTPTPTGTQTPTPTAITTTT 1504
                 +T       +G  + T         TP  +  + T +P    T   + TA+T + 
Sbjct: 1813 EADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISG 1872

Query: 1505 TVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPIS 1547
            +   TP   GT    ++    T+  + + T TG+   TP  IS
Sbjct: 1873 SKPGTP---GTPGGATSGGKITSGWSSSGTSTGSSN-TPGEIS 1911



 Score =  257 bits (656), Expect = 1e-67
 Identities = 187/654 (28%), Positives = 285/654 (43%), Gaps = 65/654 (9%)

Query: 38   STWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILLT 97
            STW    YK+F+G +F F   C Y F   C  S  +F + +KR                 
Sbjct: 598  STWSKGAYKSFNGRIFFFESSCPYTFCRHCIESGGDFNIEIKRN---------------- 641

Query: 98   IKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEK-SDAYTKVYSRAGLTLMWNREDALMLE 156
              +D   +  H+A  N  +      + G   E   D   K    A L+      D  M+ 
Sbjct: 642  --NDRQDINEHIA--NSKIPGDCPNAVGKSYEVCEDGIQKCGKVAALS-----NDYKMIC 692

Query: 157  LD----TKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED---P 209
            +D    T+ +  TC    + + L +     SDG    P  F + +  +  DVVCE    P
Sbjct: 693  IDEYCQTRDKTSTCDTYSELSRLCA-----SDG----PGTFESWR--SDSDVVCETQRCP 741

Query: 210  EEEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVA 269
            E+ +       + A C  +   +           E YL     ++ +C     C C +  
Sbjct: 742  EQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSG 801

Query: 270  EFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMD--------TCSHLE 321
               +      G  G+  T   A        CPG      S     D         C  L 
Sbjct: 802  TVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSSLTTFDGVKYNFPGNCHFLA 861

Query: 322  VSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNV--VVFKSDGSVLLNELQVNLPHV 379
            V +      ++   CP G       +V LL +    V   VF SDG+V  ++++    + 
Sbjct: 862  VHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYY 921

Query: 380  TASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDD 439
            +    +F  SS ++ V     V+LQ+Q+ PVMQL+V++         GLCG++N    DD
Sbjct: 922  SDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDD 981

Query: 440  FKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCS-LNIESANYAEHWCSLLKKTETP 498
            F ++  ++E T   FAN+W+  S          +P S ++IE   +AE  C +L  +  P
Sbjct: 982  FMSSQNILEKTSQAFANSWEMMSCPKG------NPSSCISIEKEKFAERHCGILLDSSGP 1035

Query: 499  FGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKD 558
               CH  V+P  Y++ CK  TC C+N++DCLC  L +Y +AC  K   + GWR  +C   
Sbjct: 1036 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEH- 1094

Query: 559  VGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK 618
              SCP+  VF YN+  C  +CRSLSE D  C     PVDGC CPD  + + +G CV  ++
Sbjct: 1095 --SCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQ 1152

Query: 619  CSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCR-QIRLIGQSCTAPKIHMDCSN 671
            C CY     ++ G ++   + +CVCRDG L C+  I L  Q+C+    ++DCS+
Sbjct: 1153 CDCYINDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSD 1206



 Score =  192 bits (488), Expect = 4e-48
 Identities = 138/483 (28%), Positives = 230/483 (47%), Gaps = 69/483 (14%)

Query: 658  QSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDG-LMDD--GRGG 714
            Q C    I+ +C        S P   +C  +A  +  +ECVSGC CP+G L+DD   +G 
Sbjct: 738  QRCPEQHIYKECG------PSNPA--TCSNVAP-FQDSECVSGCTCPEGYLLDDIGEKGK 788

Query: 715  CVVEKECPCVHNNDLYSSGAKIKVDCNT-CTCKRGRWVCTQAVCHGTCSIYGSGHYITFD 773
            CV++ ECPC  +  +Y  G   +  C + CTC+  +W CT+A+C G C + GS    TFD
Sbjct: 789  CVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSS-LTTFD 847

Query: 774  GKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPC--GTTGVTCSKAIKIFMGR---- 827
            G  Y+F G+C ++AV +          +SI  E  PC  G TG TC  ++ + +      
Sbjct: 848  GVKYNFPGNCHFLAVHNE--------DWSISVELRPCPSGQTG-TCLNSVTLLLNSSVPV 898

Query: 828  -----------TELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTT 876
                       T  K+ ++      + +  + + +  +V  Y  V+    I+ +      
Sbjct: 899  DKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQ---- 954

Query: 877  VFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPE 936
            +++ + P+      GLCG++++++ +DF +  +++  +   F NSW E  +CP    NP 
Sbjct: 955  LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSW-EMMSCP--KGNPS 1011

Query: 937  PCSLNPHRRSWAEKQCSIL--KSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCS 994
             C ++  +  +AE+ C IL   S   + CH  V+PKP++E C   +C+C+   D  C C+
Sbjct: 1012 SC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLCT 1068

Query: 995  AVASYAQECT-KEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIH 1053
             + +Y + C  KE   V WRT  LC   C     P    + Y      S  +CR+++   
Sbjct: 1069 ILGNYVKACAEKETYIVGWRT-GLCEHSC-----PSGLVFKYNVKACNS--SCRSLSERD 1120

Query: 1054 SNISVS--YLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKS 1111
             +  V    ++GC   CP    +Y+ +   CV   +C CY+ D    PG  + T++    
Sbjct: 1121 RSCDVEDVPVDGC--TCPD--AMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDD--NK 1174

Query: 1112 CVC 1114
            CVC
Sbjct: 1175 CVC 1177



 Score =  132 bits (333), Expect = 3e-30
 Identities = 161/677 (23%), Positives = 261/677 (38%), Gaps = 98/677 (14%)

Query: 47   TFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGP-GQAEAPAGVESILLTIKDDTIYL 105
            TFDG  + FPG C +    +   S    +V L+  P GQ        ++LL   + ++ +
Sbjct: 845  TFDGVKYNFPGNCHFLAVHNEDWS---ISVELRPCPSGQTGTCLNSVTLLL---NSSVPV 898

Query: 106  TRHLAVLNGAVVSTP------HYSPGLLI-EKSDAYTKV--YSRAGLTLMWNREDALMLE 156
             +++   +G V +        +YS  + I   S +Y +V  Y    L +       L + 
Sbjct: 899  DKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVS 958

Query: 157  LDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVVCEDPEEEVAP 215
            +       T GLCG YN         S  +L    + F N  ++    + C        P
Sbjct: 959  MPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM----MSCPKGN----P 1010

Query: 216  ASCSEHRAE------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTV 268
            +SC     E      C  LL +    A C  +V  +PY   C++  C C     C+C+ +
Sbjct: 1011 SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 1070

Query: 269  AEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTC---SHLEVSSL 325
              + + C+        WRT           +CP  LV+  +   C  +C   S  + S  
Sbjct: 1071 GNYVKACAEKETYIVGWRTGL------CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCD 1124

Query: 326  CEEHRMDG--------------------CFCPEGAQADLPKTVVLLADKK----KNVVVF 361
             E+  +DG                    C C    +   P  ++   D K      +++ 
Sbjct: 1125 VEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDDNKCVCRDGILLC 1184

Query: 362  KSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGV------------RLQVQLAP 409
            +    + L        +V  S    +  +     +  I V            R+  +  P
Sbjct: 1185 QIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDDYCGHENGTFRILTESVP 1244

Query: 410  VMQLFVTLDQ----ASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCH 465
              +  +T  +    A QG+V GLCGN NG   DDF T    V +    F N+WK    C 
Sbjct: 1245 CCEDGLTCSRKIIVAFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECS 1304

Query: 466  DKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNN 525
            D +     PC  N     +A   C +L+  ++ F  CH+ VDP+ Y+  C  + C C   
Sbjct: 1305 DTVA-QTFPCDSNPYCKAWAVRKCEILR--DSTFRDCHNKVDPSAYHDVCIEEACACDME 1361

Query: 526  EDCL--CAALSSYARACTAKGVMLWGWREHVCNK--DVGSCPNSQVFLYNL--TTCQQTC 579
               L  C A++ YA AC+A GV +   + ++C    D  + P    + Y    T   +TC
Sbjct: 1362 GKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTC 1421

Query: 580  RS--LSEADSHCLEGFAPVDGCGCPDHT-FLDEKG-RCVPLAKCSCYHRGLYLEAGDVVV 635
            +   + +  S  LEG        CPD   +LDE   +CV L++CSC++  +    G +  
Sbjct: 1422 KDQLVGQKFSSLLEGCY----AKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGVIED 1477

Query: 636  RQEERCVCRDGRLHCRQ 652
                 C C  G+L C +
Sbjct: 1478 NCGRTCYCIAGQLECSE 1494



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 113/443 (25%), Positives = 164/443 (37%), Gaps = 44/443 (9%)

Query: 1324 PTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1383
            PT +  +  +TT T I +T       T  G  T  + P  TT++   T T  G   P T 
Sbjct: 1497 PTNSTFAVSTTTATTILSTGAAITLVTG-GPSTAASIPAITTSSSETTGTTLG---PLTE 1552

Query: 1384 PITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1443
            P TT  T T  P        TS     T  V+PT T       TT  +   TT   +   
Sbjct: 1553 PFTTGITETSVPI-----ISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASEN- 1606

Query: 1444 TGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTT 1503
            T  +A TP     T  V    TP G   P  T ++ +T V+      G+ T +P A  T+
Sbjct: 1607 TSERAGTPRVSGATPAVGGGSTP-GEAGPGAT-VSGSTGVS-----AGSITASPGASATS 1659

Query: 1504 TTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQT 1563
            +  + + T TG      T  T++   +       T     +   + + +T   + TG+  
Sbjct: 1660 SESSKSGT-TGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTGSSP 1718

Query: 1564 PTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTA 1623
            P    +T  +  +P     GT     V  T       +    ST+ +     +  +  TA
Sbjct: 1719 P--GKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTA 1776

Query: 1624 TPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIA----------ELTTSN 1673
              + TG   P    +S T  V+P  TP    +  P        +           LT  N
Sbjct: 1777 GTSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLN 1836

Query: 1674 PPPESSTPQTS--RSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPP 1731
            P     TP  S   +TSSP+++ T   S     I  +    P TP     TSGG   S  
Sbjct: 1837 PAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGG--ATSGGKITS-- 1892

Query: 1732 PSTTTSPPGTPTRGTTTGSSSAP 1754
                    G  + GT+TGSS+ P
Sbjct: 1893 --------GWSSSGTSTGSSNTP 1907



 Score = 80.9 bits (198), Expect = 2e-14
 Identities = 65/249 (26%), Positives = 94/249 (37%), Gaps = 39/249 (15%)

Query: 2074 FGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAV 2133
            F     G CG       DD       + S      + W            S   +   A 
Sbjct: 1260 FQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----------SQECSDTVAQ 1309

Query: 2134 TVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCF--MPGSSLE- 2190
            T P    + P+        C++++DS F  CH  V P  Y+D C+ ++C   M G  L  
Sbjct: 1310 TFPCD--SNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1367

Query: 2191 CASLQAYAALCAQQNICLDWRNHTHGACLVECPSHR-------EYQACGPAEEPTCKSSS 2243
            C ++  YA  C+   +C+ WR      C V C  +         Y+ CG     TCK   
Sbjct: 1368 CTAVAMYAEACSAVGVCVSWRK--PNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQL 1425

Query: 2244 SQQNNTVLVEGCF--CPEGTMNYAPGFD------VCVKTCGCVGPDNVPREFGEHFEFDC 2295
              Q  + L+EGC+  CP+     AP  D      V +  C C   D +P   G   E +C
Sbjct: 1426 VGQKFSSLLEGCYAKCPDS----APYLDENTMKCVSLSECSCFYNDVIPA--GGVIEDNC 1479

Query: 2296 -KNCVCLEG 2303
             + C C+ G
Sbjct: 1480 GRTCYCIAG 1488



 Score = 79.0 bits (193), Expect = 6e-14
 Identities = 94/433 (21%), Positives = 167/433 (38%), Gaps = 62/433 (14%)

Query: 1903 IVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWG-------------DPHY 1949
            ++K EC   P  +     QP  V +  G C   +C C    W                  
Sbjct: 790  VLKAEC---PCESSGTVYQPGEVRE--GPCGS-QCTCQDAKWSCTEALCPGRCKVEGSSL 843

Query: 1950 VTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVL 2009
             TFDG+ Y++ GNC ++ V       +++ + ++   C      +C  ++ +   +   +
Sbjct: 844  TTFDGVKYNFPGNCHFLAVHN-----EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPV 898

Query: 2010 IKTVHMMPMQV-QVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN---GLSF 2065
             K V      V   ++  Q     Y    ++++ +  +Y+       V +       +  
Sbjct: 899  DKYVFNSDGTVTNDKIRNQGY---YYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQL 955

Query: 2066 SVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSS 2125
             V +P ++F  +T G CG+  N   DD +     +    +A A+ W +       CP  +
Sbjct: 956  YVSMPPNQF-TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-----CPKGN 1009

Query: 2126 STTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSL--FAQCHALVPPQHYYDACVFDSCF 2183
             ++    +++         K+      C ++ DS    A CH +V P+ Y++ C   +C 
Sbjct: 1010 PSS---CISI--------EKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCT 1058

Query: 2184 MPGSS-LECASLQAYAALCAQ-QNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKS 2241
               S    C  L  Y   CA+ +   + WR    G C   CPS   ++    A   +C+S
Sbjct: 1059 CENSQDCLCTILGNYVKACAEKETYIVGWRT---GLCEHSCPSGLVFKYNVKACNSSCRS 1115

Query: 2242 SSSQQNNT----VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKN 2297
             S +  +     V V+GC CP+       G  V    C C   D V +  G+    D   
Sbjct: 1116 LSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQP-GKLIHTDDNK 1174

Query: 2298 CVCLEGGSGIICQ 2310
            CVC +G   ++CQ
Sbjct: 1175 CVCRDG--ILLCQ 1185



 Score = 63.5 bits (153), Expect = 3e-09
 Identities = 104/413 (25%), Positives = 152/413 (36%), Gaps = 62/413 (15%)

Query: 1485 PTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPT 1544
            PT +     T T T I +T       T  G  T  S P  TT++   T T  G   P   
Sbjct: 1497 PTNSTFAVSTTTATTILSTGAAITLVTG-GPSTAASIPAITTSSSETTGTTLG---PLTE 1552

Query: 1545 PISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP 1604
            P +T  T T  P  +     T+     T  V+PT T       TT  +   TT   +   
Sbjct: 1553 PFTTGITETSVPIIS-----TSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASEN- 1606

Query: 1605 TSTKSTTVTPITTTTTVTATPTP------------TGTQTPTMIPISTTTTVTPTPTPTT 1652
            TS ++ T      T  V    TP            TG    + I  S   + T + +  +
Sbjct: 1607 TSERAGTPRVSGATPAVGGGSTPGEAGPGATVSGSTGVSAGS-ITASPGASATSSESSKS 1665

Query: 1653 GSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTS---SPLTESTTLLSTLPPAIEMTS 1709
            G+TGP     T   +   TS+      T Q+  ST+   S +T  T+   + PP  ++T 
Sbjct: 1666 GTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTGSSPPG-KLTR 1724

Query: 1710 TAPPSTP-----------TAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPST 1758
             +P S              A T  +G +T     ST  S   T + G+   + ++ T  T
Sbjct: 1725 PSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDT 1784

Query: 1759 VQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGE-EVYNGTYGDT 1817
                T  + TP  +P +TP           P S             PGE ++ N ++G +
Sbjct: 1785 GPGNTAVSGTPVVSPGATPGA---------PGS-----------STPGEADIGNTSFGKS 1824

Query: 1818 CYFVNCSLSCTLEFYNWSCP--STPSPTPTP-SKSTPTPSKPSSTPSKPTPGT 1867
                + SL+     +    P  S  S T +P SK T   S  + T S   PGT
Sbjct: 1825 GKSGHDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGT 1877



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 4/91 (4%)

Query: 2173 YYDACVFDSCFMPGSSLECASLQAYAALCAQQN--ICLDWRNHTHGACLVE-CPSHREYQ 2229
            Y   C+ + C     +  C +    + LCA         WR+ +   C  + CP    Y+
Sbjct: 688  YKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYK 747

Query: 2230 ACGPAEEPTCKSSSSQQNNTVLVEGCFCPEG 2260
             CGP+   TC + +  Q++   V GC CPEG
Sbjct: 748  ECGPSNPATCSNVAPFQDSE-CVSGCTCPEG 777



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 46/172 (26%), Positives = 67/172 (38%), Gaps = 29/172 (16%)

Query: 603  DHTFLDEKGRCVPLA--------KCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIR 654
            D TF D   +  P A         C+C   G YL     V    E C      +  R+  
Sbjct: 1332 DSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPN 1391

Query: 655  LIGQSC---TAP---KIHMD-CSNLTALATSKPRALSCQTLAAGYYHTECVSGCV--CPD 705
            L    C    AP   + H + C  +TA         +C+    G   +  + GC   CPD
Sbjct: 1392 LCPVYCDYYNAPGECRWHYEPCGTVTAK--------TCKDQLVGQKFSSLLEGCYAKCPD 1443

Query: 706  GL--MDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDC-NTCTCKRGRWVCTQ 754
                +D+    CV   EC C + ND+  +G  I+ +C  TC C  G+  C++
Sbjct: 1444 SAPYLDENTMKCVSLSECSCFY-NDVIPAGGVIEDNCGRTCYCIAGQLECSE 1494


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score =  232 bits (592), Expect = 3e-60
 Identities = 225/775 (29%), Positives = 292/775 (37%), Gaps = 114/775 (14%)

Query: 1160 TTRPSTLTTFTTITLPTTPTTFT----TTTTTTTPTSSTVLS--TTPKLCCLWSDWINED 1213
            T +  T T    +T P  PT  T     +TT   PT +T+ S  TTPK     +    + 
Sbjct: 198  TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP---APTTTKS 254

Query: 1214 HPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQ 1273
             P++  +     T +     P++    + K+P  +  +                     +
Sbjct: 255  APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP-------APTTPK 307

Query: 1274 KPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQS 1333
            KP    P                 T P   T TT + P PT      T    P PT+ + 
Sbjct: 308  KPAPTTPKE------------PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 355

Query: 1334 ---TTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1390
               TTP     TT   P PT T   +PTT      TT    PT T    PTTT    TT 
Sbjct: 356  PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415

Query: 1391 VTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGTQAP 1449
              P+PT T    PT TP     T    P PT  + P  TTP     T T  P PT  + P
Sbjct: 416  KEPSPTTTKEPAPT-TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 474

Query: 1450 TPTAITTTSTVTP---TPT------PTGTQTPT-TTPITTTTTVTPTPTPTGTQTPTPT- 1498
             PT    T+  TP   TPT      PT  + P  TTP     T    PTPT  + P PT 
Sbjct: 475  APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT 534

Query: 1499 ------------AITT------TTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQT 1540
                        A TT      TT   P PT T  +T  +TP  T  T    P PT  + 
Sbjct: 535  PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-TPKETAPTTPKGTAPTTLKEPAPTTPKK 593

Query: 1541 PTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTVLITTTTTMT 1599
            P P  ++ TTT  PT T      PTT   T  TT   P PT      PTT   T  TT+ 
Sbjct: 594  PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK 653

Query: 1600 PTPTPTSTK---------STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTP 1650
              P PT+ K         +TT  P +TT+   A  TP  T   T  P     T    P P
Sbjct: 654  E-PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT--PKEPAPTTPKKPAP 710

Query: 1651 TTGSTGPPTHTSTAP---IAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 1707
            TT  T PPT +  +      E TT +  P+ STP+ S   +    E++     +P     
Sbjct: 711  TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP 770

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTT--GSSSAPTPSTVQTTTTS 1765
             +T P  T TA   T+     + P +TT +P  T    TTT   + S  T +T Q T+T+
Sbjct: 771  AATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTT 830

Query: 1766 AWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSL 1825
                TP  ++T   ++TT L P  ++        +    P E                  
Sbjct: 831  TQDTTPFKITT---LKTTTLAPKVTTTKKTITTTEIMNKPEE------------------ 869

Query: 1826 SCTLEFYNWSCPSTPSPTPTPSK-STPTPSKPSSTPSKPTPGTKPPECPDFDPPR 1879
                        + P    T SK +TP P KP+  P KPT   KP   P    P+
Sbjct: 870  -----------TAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPK 913



 Score =  216 bits (550), Expect = 2e-55
 Identities = 199/615 (32%), Positives = 240/615 (39%), Gaps = 75/615 (12%)

Query: 1297 VTQPTTMTTTTTENPT-PTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQ 1355
            + +PT    TTT+ P   TP   T T    P  T+ +  TPT I +  T    P PT T+
Sbjct: 194  LAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 253

Query: 1356 TPTTTPI--TTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPT----PTPTGTQTPT-ST 1406
            +  TTP     TTT  P PT      PTTT  P  TTT   PT    P PT  + P  +T
Sbjct: 254  SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 313

Query: 1407 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPT-----AITT----- 1456
            P     T    PTPT  + P  T      T    P PT  + P PT     A TT     
Sbjct: 314  PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 373

Query: 1457 -TSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGT 1515
             T+T  P+PT      PTTT    TTT  P PT T +   TP   + TTT  P PT    
Sbjct: 374  PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 433

Query: 1516 QTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTP-TPTPTGTQTPTTTPITTTTT 1574
              PT TP     T    P PT  + P PT        TP  P PT   TP  T  TT   
Sbjct: 434  PAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT---TPKETAPTTPKK 489

Query: 1575 VTP-TPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTP 1633
            +TP TP      TP     TT   + PT     T +T   P  TT    A  TP      
Sbjct: 490  LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 549

Query: 1634 TMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPI-----AELTTSNPPPESSTPQTSR--- 1685
            T    + TT   P PT T   T P T   TAP      A  T   P P+   P T++   
Sbjct: 550  TPKEPAPTTPKEPAPT-TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 608

Query: 1686 STSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSG--GHTLSPPPSTTTSPPG--- 1740
            ST+      TT   T P   +  +   P  P APTT  G    TL  P  TT   P    
Sbjct: 609  STTCDKPAPTTPKGTAPTTPKEPAPTTPKEP-APTTPKGTAPTTLKEPAPTTPKKPAPKE 667

Query: 1741 ---TPTRGTTTGSSSAPTPST-VQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICC 1796
               T T+G T+ +S  P P+T  +T  T+   P PT    P+   TT   P P++     
Sbjct: 668  LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA--PTTPETPPPTT----- 720

Query: 1797 VLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTP--SPTPTPSKSTPTPS 1854
                       EV   T       ++ S             STP  S  PTP     +P 
Sbjct: 721  ----------SEVSTPTTTKEPTTIHKSPD----------ESTPELSAEPTPKALENSPK 760

Query: 1855 KPSSTPSKPTPGTKP 1869
            +P    +K    TKP
Sbjct: 761  EPGVPTTKTPAATKP 775



 Score =  214 bits (544), Expect = 1e-54
 Identities = 197/631 (31%), Positives = 240/631 (38%), Gaps = 75/631 (11%)

Query: 1285 LNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTP--TPTSTQSTTPTPITTT 1342
            +N E  V+  E  T     +T   E  T    T +   T      PTS     PTP   T
Sbjct: 144  VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET 203

Query: 1343 TTVTPT------PTPTGTQTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1394
            TT  P       PTPT  + P  TT    T TT+   PT      PTTT    TT   P 
Sbjct: 204  TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 263

Query: 1395 PTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAI 1454
            PT T    PT TP     T T  P PT T++  TTP     T    P PT  + P PT  
Sbjct: 264  PTTTKEPAPT-TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 322

Query: 1455 TTTSTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAI---TTTTTVTPTP 1510
               +  TP  P PT  +   TTP     T    P PT  + P PT       TTT  P+P
Sbjct: 323  KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 382

Query: 1511 TPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPIT 1570
            T      PT+T    TTT  P PT T +   TP   S TTT  P PT      PTT P  
Sbjct: 383  TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT-PKK 441

Query: 1571 TTTTVTPTPTPTGTQTP---TTVLITTTTTMTPTPT-PTSTKSTTVTPITTTTTVTATPT 1626
               T    P PT  + P   TT     TT   P PT P  T  TT   +T TT     PT
Sbjct: 442  PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 501

Query: 1627 PTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRS 1686
                  PT  P     T    PTPTT     PT                P+++ P T + 
Sbjct: 502  TPEKPAPTT-PEELAPTTPEEPTPTTPEEPAPT---------------TPKAAAPNTPKE 545

Query: 1687 TSSPLTESTTLLSTLPPAIEMTSTAPPSTP--TAPTTTSGGHTLSPPPSTTTSPPG---- 1740
             +    +     +   PA        P+TP  TAPT      TL  P  TT   P     
Sbjct: 546  PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKEL 599

Query: 1741 --TPTRGTTTGSSSAPTPSTVQ-TTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCV 1797
              T T+  T+ +   P P+T + T  T+   P PT    P+   TT     P+++     
Sbjct: 600  APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA--PTTPKGTAPTTLKEPAP 657

Query: 1798 LNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTP-TPSKP 1856
                  AP E     T G T                 +    P+PT TP ++ P TP +P
Sbjct: 658  TTPKKPAPKELAPTTTKGPTS----------------TTSDKPAPT-TPKETAPTTPKEP 700

Query: 1857 S-STPSKP---TPGTKPPECPDFDPPRQENE 1883
            + +TP KP   TP T PP   +   P    E
Sbjct: 701  APTTPKKPAPTTPETPPPTTSEVSTPTTTKE 731



 Score =  185 bits (469), Expect = 6e-46
 Identities = 158/490 (32%), Positives = 196/490 (40%), Gaps = 27/490 (5%)

Query: 1298 TQPTTMTTTTTENPTPT----PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTG 1353
            T P  +  TT E PTPT    P  TT       TP     TTP     TT   P PT T 
Sbjct: 509  TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-TP 567

Query: 1354 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTT 1413
             +T  TTP  T  T    P PT  + P    +  TTT  PT T      PT TP  T  T
Sbjct: 568  KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT-TPKGTAPT 626

Query: 1414 VTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTP 1472
                P PT  + P  TTP  T  T    P PT  + P P  +  T+T  PT T +    P
Sbjct: 627  TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 686

Query: 1473 TTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPT 1532
            TT P  T  T    P PT  + P PT     T  TP PT +   TPT+T   TT   +P 
Sbjct: 687  TT-PKETAPTTPKEPAPTTPKKPAPT-----TPETPPPTTSEVSTPTTTKEPTTIHKSPD 740

Query: 1533 P-TPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVL 1591
              TP  +  PTP  +  +      PT   T+TP  T    TTT     T    +T  T  
Sbjct: 741  ESTPELSAEPTPKALENSPKEPGVPT---TKTPAATKPEMTTTAKDKTTERDLRT--TPE 795

Query: 1592 ITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPT 1651
             TT        T T+T+ TT + IT TTT   T T T   TP  I    TTT+ P  T T
Sbjct: 796  TTTAAPKMTKETATTTEKTTESKITATTT-QVTSTTTQDTTPFKITTLKTTTLAPKVT-T 853

Query: 1652 TGSTGPPTHTSTAP--IAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            T  T   T     P   A+        +++TP+  + T +P   ++T      P +    
Sbjct: 854  TKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRK-- 911

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTP 1769
              P +TPT    TS    L+P      +   T TR   T +S     +        A   
Sbjct: 912  --PKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 969

Query: 1770 TPTPLSTPSI 1779
            TP  L  P +
Sbjct: 970  TPHMLLRPHV 979



 Score =  167 bits (423), Expect = 1e-40
 Identities = 193/690 (27%), Positives = 241/690 (34%), Gaps = 124/690 (17%)

Query: 1282 AFCLNYEINVQCCE-----CVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTP 1336
            A C  Y+   +CC      C          T + PTP P            P   ++ + 
Sbjct: 47   AQCKKYD---KCCPDYESFCAEVKDNKKNRTKKKPTPKP------------PVVDEAGSG 91

Query: 1337 TPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT-PTGTQTPTTTPITT---TTTV 1391
                     TP  + T     +T+P ITT   + P P+ P  + T   T +T    TT  
Sbjct: 92   LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 151

Query: 1392 TPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTP 1451
            T   T T  QT T     TT+               T  I  T+     PT      PTP
Sbjct: 152  TKETTTTNKQTSTDGKEKTTSA------------KETQSIEKTSAKDLAPTSKVLAKPTP 199

Query: 1452 TAITTTS----TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVT 1507
             A TTT     T    PTPT  + P +T     T  T    PT  + P PT   +  T  
Sbjct: 200  KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 259

Query: 1508 PTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTT 1567
              P PT T+ P  T     T   P PT T    PT T  + TT   P PT      PTT 
Sbjct: 260  KEPAPTTTKEPAPT-----TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 314

Query: 1568 PITTTTTVT-PTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPT 1626
                 TT   PTPT      PTT     TT   P PT     + T TP     T    P 
Sbjct: 315  KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKEPA 373

Query: 1627 PTGTQTPTMIPISTTTTVTPTPT-----PTTGSTGPPTHTSTAPI-----AELTTSNPPP 1676
            PT T+ P     S TT   P PT     PTT     PT T +AP      +  TT  P P
Sbjct: 374  PTTTKEP-----SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428

Query: 1677 ESSTPQTSRSTSSPLTESTTLLSTLP-----PAIEMTSTAPPSTPTAPTTTSGGHTLSPP 1731
              +TP+    T+      TT     P     PA   T    P+TP  P  T+   T    
Sbjct: 429  --TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 486

Query: 1732 PSTTTSPPGTPTR-GTTTGSSSAP-TPSTVQTTTTSAWTPT----PTPLSTPSIIRTTGL 1785
            P   T  P TP +   TT    AP TP  +  TT    TPT    P P +  +    T  
Sbjct: 487  PKKLT--PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 544

Query: 1786 RPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPT 1845
             P P++             P E                           + P  P+PT T
Sbjct: 545  EPAPTT-------------PKEPAP------------------------TTPKEPAPT-T 566

Query: 1846 PSKSTPTPSKPS--STPSKPTPGT-KPPECPDFDPPRQENETWWLCDCFMATCKYNNTVE 1902
            P ++ PT  K +  +T  +P P T K P   +  P   +  T   CD    T     T  
Sbjct: 567  PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP-KGTAP 625

Query: 1903 IVKVECEP----PPMPTCSNGLQPVRVEDP 1928
                E  P     P PT   G  P  +++P
Sbjct: 626  TTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 655



 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 85/271 (31%), Positives = 104/271 (38%), Gaps = 16/271 (5%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQT 1356
            V+ PTT    TT + +P   T   +  PTP         P   TT T     P  T T  
Sbjct: 723  VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 782

Query: 1357 PTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTSTPITTTT 1412
              TT     TT  T T  P  T  +T TTT  TT + +T T T  T T T  +TP   TT
Sbjct: 783  DKTTERDLRTTPETTTAAPKMT-KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 841

Query: 1413 TVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQAPTPTAITTTSTVTPTPT---PTG 1468
              T T  P  T T  T  ITTT  +  P  T       T +  TT     PT     PT 
Sbjct: 842  LKTTTLAPKVTTTKKT--ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 899

Query: 1469 TQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTT 1528
            T+ P T P       TPTP      T T   +  T+ +      T T+ P  TP +    
Sbjct: 900  TKKPKTMPRVRKPKTTPTPR---KMTSTMPELNPTSRIAEAMLQTTTR-PNQTPNSKLVE 955

Query: 1529 VTP-TPTPTGTQTPTPTPISTTTTVTPTPTP 1558
            V P +    G +  TP  +       P  TP
Sbjct: 956  VNPKSEDAGGAEGETPHMLLRPHVFMPEVTP 986


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score =  232 bits (592), Expect = 3e-60
 Identities = 225/775 (29%), Positives = 292/775 (37%), Gaps = 114/775 (14%)

Query: 1160 TTRPSTLTTFTTITLPTTPTTFT----TTTTTTTPTSSTVLS--TTPKLCCLWSDWINED 1213
            T +  T T    +T P  PT  T     +TT   PT +T+ S  TTPK     +    + 
Sbjct: 239  TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP---APTTTKS 295

Query: 1214 HPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQ 1273
             P++  +     T +     P++    + K+P  +  +                     +
Sbjct: 296  APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP-------APTTPK 348

Query: 1274 KPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQS 1333
            KP    P                 T P   T TT + P PT      T    P PT+ + 
Sbjct: 349  KPAPTTPKE------------PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 396

Query: 1334 ---TTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1390
               TTP     TT   P PT T   +PTT      TT    PT T    PTTT    TT 
Sbjct: 397  PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456

Query: 1391 VTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGTQAP 1449
              P+PT T    PT TP     T    P PT  + P  TTP     T T  P PT  + P
Sbjct: 457  KEPSPTTTKEPAPT-TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 515

Query: 1450 TPTAITTTSTVTP---TPT------PTGTQTPT-TTPITTTTTVTPTPTPTGTQTPTPT- 1498
             PT    T+  TP   TPT      PT  + P  TTP     T    PTPT  + P PT 
Sbjct: 516  APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT 575

Query: 1499 ------------AITT------TTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQT 1540
                        A TT      TT   P PT T  +T  +TP  T  T    P PT  + 
Sbjct: 576  PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-TPKETAPTTPKGTAPTTLKEPAPTTPKK 634

Query: 1541 PTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTVLITTTTTMT 1599
            P P  ++ TTT  PT T      PTT   T  TT   P PT      PTT   T  TT+ 
Sbjct: 635  PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK 694

Query: 1600 PTPTPTSTK---------STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTP 1650
              P PT+ K         +TT  P +TT+   A  TP  T   T  P     T    P P
Sbjct: 695  E-PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT--PKEPAPTTPKKPAP 751

Query: 1651 TTGSTGPPTHTSTAP---IAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 1707
            TT  T PPT +  +      E TT +  P+ STP+ S   +    E++     +P     
Sbjct: 752  TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP 811

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTT--GSSSAPTPSTVQTTTTS 1765
             +T P  T TA   T+     + P +TT +P  T    TTT   + S  T +T Q T+T+
Sbjct: 812  AATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTT 871

Query: 1766 AWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSL 1825
                TP  ++T   ++TT L P  ++        +    P E                  
Sbjct: 872  TQDTTPFKITT---LKTTTLAPKVTTTKKTITTTEIMNKPEE------------------ 910

Query: 1826 SCTLEFYNWSCPSTPSPTPTPSK-STPTPSKPSSTPSKPTPGTKPPECPDFDPPR 1879
                        + P    T SK +TP P KP+  P KPT   KP   P    P+
Sbjct: 911  -----------TAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPK 954



 Score =  216 bits (550), Expect = 2e-55
 Identities = 199/615 (32%), Positives = 240/615 (39%), Gaps = 75/615 (12%)

Query: 1297 VTQPTTMTTTTTENPT-PTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQ 1355
            + +PT    TTT+ P   TP   T T    P  T+ +  TPT I +  T    P PT T+
Sbjct: 235  LAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 294

Query: 1356 TPTTTPI--TTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPT----PTPTGTQTPT-ST 1406
            +  TTP     TTT  P PT      PTTT  P  TTT   PT    P PT  + P  +T
Sbjct: 295  SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 354

Query: 1407 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPT-----AITT----- 1456
            P     T    PTPT  + P  T      T    P PT  + P PT     A TT     
Sbjct: 355  PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 414

Query: 1457 -TSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGT 1515
             T+T  P+PT      PTTT    TTT  P PT T +   TP   + TTT  P PT    
Sbjct: 415  PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 474

Query: 1516 QTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTP-TPTPTGTQTPTTTPITTTTT 1574
              PT TP     T    P PT  + P PT        TP  P PT   TP  T  TT   
Sbjct: 475  PAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT---TPKETAPTTPKK 530

Query: 1575 VTP-TPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTP 1633
            +TP TP      TP     TT   + PT     T +T   P  TT    A  TP      
Sbjct: 531  LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 590

Query: 1634 TMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPI-----AELTTSNPPPESSTPQTSR--- 1685
            T    + TT   P PT T   T P T   TAP      A  T   P P+   P T++   
Sbjct: 591  TPKEPAPTTPKEPAPT-TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 649

Query: 1686 STSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSG--GHTLSPPPSTTTSPPG--- 1740
            ST+      TT   T P   +  +   P  P APTT  G    TL  P  TT   P    
Sbjct: 650  STTCDKPAPTTPKGTAPTTPKEPAPTTPKEP-APTTPKGTAPTTLKEPAPTTPKKPAPKE 708

Query: 1741 ---TPTRGTTTGSSSAPTPST-VQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICC 1796
               T T+G T+ +S  P P+T  +T  T+   P PT    P+   TT   P P++     
Sbjct: 709  LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA--PTTPETPPPTT----- 761

Query: 1797 VLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTP--SPTPTPSKSTPTPS 1854
                       EV   T       ++ S             STP  S  PTP     +P 
Sbjct: 762  ----------SEVSTPTTTKEPTTIHKSPD----------ESTPELSAEPTPKALENSPK 801

Query: 1855 KPSSTPSKPTPGTKP 1869
            +P    +K    TKP
Sbjct: 802  EPGVPTTKTPAATKP 816



 Score =  214 bits (544), Expect = 1e-54
 Identities = 197/631 (31%), Positives = 240/631 (38%), Gaps = 75/631 (11%)

Query: 1285 LNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTP--TPTSTQSTTPTPITTT 1342
            +N E  V+  E  T     +T   E  T    T +   T      PTS     PTP   T
Sbjct: 185  VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET 244

Query: 1343 TTVTPT------PTPTGTQTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1394
            TT  P       PTPT  + P  TT    T TT+   PT      PTTT    TT   P 
Sbjct: 245  TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 304

Query: 1395 PTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAI 1454
            PT T    PT TP     T T  P PT T++  TTP     T    P PT  + P PT  
Sbjct: 305  PTTTKEPAPT-TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 363

Query: 1455 TTTSTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAI---TTTTTVTPTP 1510
               +  TP  P PT  +   TTP     T    P PT  + P PT       TTT  P+P
Sbjct: 364  KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 423

Query: 1511 TPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPIT 1570
            T      PT+T    TTT  P PT T +   TP   S TTT  P PT      PTT P  
Sbjct: 424  TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT-PKK 482

Query: 1571 TTTTVTPTPTPTGTQTP---TTVLITTTTTMTPTPT-PTSTKSTTVTPITTTTTVTATPT 1626
               T    P PT  + P   TT     TT   P PT P  T  TT   +T TT     PT
Sbjct: 483  PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 542

Query: 1627 PTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRS 1686
                  PT  P     T    PTPTT     PT                P+++ P T + 
Sbjct: 543  TPEKPAPTT-PEELAPTTPEEPTPTTPEEPAPT---------------TPKAAAPNTPKE 586

Query: 1687 TSSPLTESTTLLSTLPPAIEMTSTAPPSTP--TAPTTTSGGHTLSPPPSTTTSPPG---- 1740
             +    +     +   PA        P+TP  TAPT      TL  P  TT   P     
Sbjct: 587  PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKEL 640

Query: 1741 --TPTRGTTTGSSSAPTPSTVQ-TTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCV 1797
              T T+  T+ +   P P+T + T  T+   P PT    P+   TT     P+++     
Sbjct: 641  APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA--PTTPKGTAPTTLKEPAP 698

Query: 1798 LNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTP-TPSKP 1856
                  AP E     T G T                 +    P+PT TP ++ P TP +P
Sbjct: 699  TTPKKPAPKELAPTTTKGPTS----------------TTSDKPAPT-TPKETAPTTPKEP 741

Query: 1857 S-STPSKP---TPGTKPPECPDFDPPRQENE 1883
            + +TP KP   TP T PP   +   P    E
Sbjct: 742  APTTPKKPAPTTPETPPPTTSEVSTPTTTKE 772



 Score =  185 bits (469), Expect = 6e-46
 Identities = 158/490 (32%), Positives = 196/490 (40%), Gaps = 27/490 (5%)

Query: 1298 TQPTTMTTTTTENPTPT----PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTG 1353
            T P  +  TT E PTPT    P  TT       TP     TTP     TT   P PT T 
Sbjct: 550  TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-TP 608

Query: 1354 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTT 1413
             +T  TTP  T  T    P PT  + P    +  TTT  PT T      PT TP  T  T
Sbjct: 609  KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT-TPKGTAPT 667

Query: 1414 VTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTP 1472
                P PT  + P  TTP  T  T    P PT  + P P  +  T+T  PT T +    P
Sbjct: 668  TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 727

Query: 1473 TTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPT 1532
            TT P  T  T    P PT  + P PT     T  TP PT +   TPT+T   TT   +P 
Sbjct: 728  TT-PKETAPTTPKEPAPTTPKKPAPT-----TPETPPPTTSEVSTPTTTKEPTTIHKSPD 781

Query: 1533 P-TPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVL 1591
              TP  +  PTP  +  +      PT   T+TP  T    TTT     T    +T  T  
Sbjct: 782  ESTPELSAEPTPKALENSPKEPGVPT---TKTPAATKPEMTTTAKDKTTERDLRT--TPE 836

Query: 1592 ITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPT 1651
             TT        T T+T+ TT + IT TTT   T T T   TP  I    TTT+ P  T T
Sbjct: 837  TTTAAPKMTKETATTTEKTTESKITATTT-QVTSTTTQDTTPFKITTLKTTTLAPKVT-T 894

Query: 1652 TGSTGPPTHTSTAP--IAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            T  T   T     P   A+        +++TP+  + T +P   ++T      P +    
Sbjct: 895  TKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRK-- 952

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTP 1769
              P +TPT    TS    L+P      +   T TR   T +S     +        A   
Sbjct: 953  --PKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1010

Query: 1770 TPTPLSTPSI 1779
            TP  L  P +
Sbjct: 1011 TPHMLLRPHV 1020



 Score =  167 bits (423), Expect = 1e-40
 Identities = 193/690 (27%), Positives = 241/690 (34%), Gaps = 124/690 (17%)

Query: 1282 AFCLNYEINVQCCE-----CVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTP 1336
            A C  Y+   +CC      C          T + PTP P            P   ++ + 
Sbjct: 88   AQCKKYD---KCCPDYESFCAEVKDNKKNRTKKKPTPKP------------PVVDEAGSG 132

Query: 1337 TPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPT-PTGTQTPTTTPITT---TTTV 1391
                     TP  + T     +T+P ITT   + P P+ P  + T   T +T    TT  
Sbjct: 133  LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 192

Query: 1392 TPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTP 1451
            T   T T  QT T     TT+               T  I  T+     PT      PTP
Sbjct: 193  TKETTTTNKQTSTDGKEKTTSA------------KETQSIEKTSAKDLAPTSKVLAKPTP 240

Query: 1452 TAITTTS----TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVT 1507
             A TTT     T    PTPT  + P +T     T  T    PT  + P PT   +  T  
Sbjct: 241  KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 300

Query: 1508 PTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTT 1567
              P PT T+ P  T     T   P PT T    PT T  + TT   P PT      PTT 
Sbjct: 301  KEPAPTTTKEPAPT-----TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 355

Query: 1568 PITTTTTVT-PTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPT 1626
                 TT   PTPT      PTT     TT   P PT     + T TP     T    P 
Sbjct: 356  KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKEPA 414

Query: 1627 PTGTQTPTMIPISTTTTVTPTPT-----PTTGSTGPPTHTSTAPI-----AELTTSNPPP 1676
            PT T+ P     S TT   P PT     PTT     PT T +AP      +  TT  P P
Sbjct: 415  PTTTKEP-----SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469

Query: 1677 ESSTPQTSRSTSSPLTESTTLLSTLP-----PAIEMTSTAPPSTPTAPTTTSGGHTLSPP 1731
              +TP+    T+      TT     P     PA   T    P+TP  P  T+   T    
Sbjct: 470  --TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 527

Query: 1732 PSTTTSPPGTPTR-GTTTGSSSAP-TPSTVQTTTTSAWTPT----PTPLSTPSIIRTTGL 1785
            P   T  P TP +   TT    AP TP  +  TT    TPT    P P +  +    T  
Sbjct: 528  PKKLT--PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 585

Query: 1786 RPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPT 1845
             P P++             P E                           + P  P+PT T
Sbjct: 586  EPAPTT-------------PKEPAP------------------------TTPKEPAPT-T 607

Query: 1846 PSKSTPTPSKPS--STPSKPTPGT-KPPECPDFDPPRQENETWWLCDCFMATCKYNNTVE 1902
            P ++ PT  K +  +T  +P P T K P   +  P   +  T   CD    T     T  
Sbjct: 608  PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP-KGTAP 666

Query: 1903 IVKVECEP----PPMPTCSNGLQPVRVEDP 1928
                E  P     P PT   G  P  +++P
Sbjct: 667  TTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 696



 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 85/271 (31%), Positives = 104/271 (38%), Gaps = 16/271 (5%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQT 1356
            V+ PTT    TT + +P   T   +  PTP         P   TT T     P  T T  
Sbjct: 764  VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 823

Query: 1357 PTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTSTPITTTT 1412
              TT     TT  T T  P  T  +T TTT  TT + +T T T  T T T  +TP   TT
Sbjct: 824  DKTTERDLRTTPETTTAAPKMT-KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 882

Query: 1413 TVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQAPTPTAITTTSTVTPTPT---PTG 1468
              T T  P  T T  T  ITTT  +  P  T       T +  TT     PT     PT 
Sbjct: 883  LKTTTLAPKVTTTKKT--ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 940

Query: 1469 TQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTT 1528
            T+ P T P       TPTP      T T   +  T+ +      T T+ P  TP +    
Sbjct: 941  TKKPKTMPRVRKPKTTPTPR---KMTSTMPELNPTSRIAEAMLQTTTR-PNQTPNSKLVE 996

Query: 1529 VTP-TPTPTGTQTPTPTPISTTTTVTPTPTP 1558
            V P +    G +  TP  +       P  TP
Sbjct: 997  VNPKSEDAGGAEGETPHMLLRPHVFMPEVTP 1027


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score =  232 bits (592), Expect = 3e-60
 Identities = 225/775 (29%), Positives = 292/775 (37%), Gaps = 114/775 (14%)

Query: 1160 TTRPSTLTTFTTITLPTTPTTFT----TTTTTTTPTSSTVLS--TTPKLCCLWSDWINED 1213
            T +  T T    +T P  PT  T     +TT   PT +T+ S  TTPK     +    + 
Sbjct: 291  TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP---APTTTKS 347

Query: 1214 HPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQ 1273
             P++  +     T +     P++    + K+P  +  +                     +
Sbjct: 348  APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP-------APTTPK 400

Query: 1274 KPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQS 1333
            KP    P                 T P   T TT + P PT      T    P PT+ + 
Sbjct: 401  KPAPTTPKE------------PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 448

Query: 1334 ---TTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1390
               TTP     TT   P PT T   +PTT      TT    PT T    PTTT    TT 
Sbjct: 449  PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 508

Query: 1391 VTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGTQAP 1449
              P+PT T    PT TP     T    P PT  + P  TTP     T T  P PT  + P
Sbjct: 509  KEPSPTTTKEPAPT-TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 567

Query: 1450 TPTAITTTSTVTP---TPT------PTGTQTPT-TTPITTTTTVTPTPTPTGTQTPTPT- 1498
             PT    T+  TP   TPT      PT  + P  TTP     T    PTPT  + P PT 
Sbjct: 568  APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT 627

Query: 1499 ------------AITT------TTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQT 1540
                        A TT      TT   P PT T  +T  +TP  T  T    P PT  + 
Sbjct: 628  PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-TPKETAPTTPKGTAPTTLKEPAPTTPKK 686

Query: 1541 PTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTVLITTTTTMT 1599
            P P  ++ TTT  PT T      PTT   T  TT   P PT      PTT   T  TT+ 
Sbjct: 687  PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK 746

Query: 1600 PTPTPTSTK---------STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTP 1650
              P PT+ K         +TT  P +TT+   A  TP  T   T  P     T    P P
Sbjct: 747  E-PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT--PKEPAPTTPKKPAP 803

Query: 1651 TTGSTGPPTHTSTAP---IAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 1707
            TT  T PPT +  +      E TT +  P+ STP+ S   +    E++     +P     
Sbjct: 804  TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP 863

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTT--GSSSAPTPSTVQTTTTS 1765
             +T P  T TA   T+     + P +TT +P  T    TTT   + S  T +T Q T+T+
Sbjct: 864  AATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTT 923

Query: 1766 AWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSL 1825
                TP  ++T   ++TT L P  ++        +    P E                  
Sbjct: 924  TQDTTPFKITT---LKTTTLAPKVTTTKKTITTTEIMNKPEE------------------ 962

Query: 1826 SCTLEFYNWSCPSTPSPTPTPSK-STPTPSKPSSTPSKPTPGTKPPECPDFDPPR 1879
                        + P    T SK +TP P KP+  P KPT   KP   P    P+
Sbjct: 963  -----------TAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPK 1006



 Score =  216 bits (550), Expect = 2e-55
 Identities = 199/615 (32%), Positives = 240/615 (39%), Gaps = 75/615 (12%)

Query: 1297 VTQPTTMTTTTTENPT-PTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQ 1355
            + +PT    TTT+ P   TP   T T    P  T+ +  TPT I +  T    P PT T+
Sbjct: 287  LAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 346

Query: 1356 TPTTTPI--TTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPT----PTPTGTQTPT-ST 1406
            +  TTP     TTT  P PT      PTTT  P  TTT   PT    P PT  + P  +T
Sbjct: 347  SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 406

Query: 1407 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPT-----AITT----- 1456
            P     T    PTPT  + P  T      T    P PT  + P PT     A TT     
Sbjct: 407  PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 466

Query: 1457 -TSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGT 1515
             T+T  P+PT      PTTT    TTT  P PT T +   TP   + TTT  P PT    
Sbjct: 467  PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 526

Query: 1516 QTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTP-TPTPTGTQTPTTTPITTTTT 1574
              PT TP     T    P PT  + P PT        TP  P PT   TP  T  TT   
Sbjct: 527  PAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT---TPKETAPTTPKK 582

Query: 1575 VTP-TPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTP 1633
            +TP TP      TP     TT   + PT     T +T   P  TT    A  TP      
Sbjct: 583  LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 642

Query: 1634 TMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPI-----AELTTSNPPPESSTPQTSR--- 1685
            T    + TT   P PT T   T P T   TAP      A  T   P P+   P T++   
Sbjct: 643  TPKEPAPTTPKEPAPT-TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 701

Query: 1686 STSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSG--GHTLSPPPSTTTSPPG--- 1740
            ST+      TT   T P   +  +   P  P APTT  G    TL  P  TT   P    
Sbjct: 702  STTCDKPAPTTPKGTAPTTPKEPAPTTPKEP-APTTPKGTAPTTLKEPAPTTPKKPAPKE 760

Query: 1741 ---TPTRGTTTGSSSAPTPST-VQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICC 1796
               T T+G T+ +S  P P+T  +T  T+   P PT    P+   TT   P P++     
Sbjct: 761  LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA--PTTPETPPPTT----- 813

Query: 1797 VLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTP--SPTPTPSKSTPTPS 1854
                       EV   T       ++ S             STP  S  PTP     +P 
Sbjct: 814  ----------SEVSTPTTTKEPTTIHKSPD----------ESTPELSAEPTPKALENSPK 853

Query: 1855 KPSSTPSKPTPGTKP 1869
            +P    +K    TKP
Sbjct: 854  EPGVPTTKTPAATKP 868



 Score =  214 bits (544), Expect = 1e-54
 Identities = 197/631 (31%), Positives = 240/631 (38%), Gaps = 75/631 (11%)

Query: 1285 LNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTP--TPTSTQSTTPTPITTT 1342
            +N E  V+  E  T     +T   E  T    T +   T      PTS     PTP   T
Sbjct: 237  VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET 296

Query: 1343 TTVTPT------PTPTGTQTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1394
            TT  P       PTPT  + P  TT    T TT+   PT      PTTT    TT   P 
Sbjct: 297  TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 356

Query: 1395 PTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAI 1454
            PT T    PT TP     T T  P PT T++  TTP     T    P PT  + P PT  
Sbjct: 357  PTTTKEPAPT-TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 415

Query: 1455 TTTSTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAI---TTTTTVTPTP 1510
               +  TP  P PT  +   TTP     T    P PT  + P PT       TTT  P+P
Sbjct: 416  KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 475

Query: 1511 TPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPIT 1570
            T      PT+T    TTT  P PT T +   TP   S TTT  P PT      PTT P  
Sbjct: 476  TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT-PKK 534

Query: 1571 TTTTVTPTPTPTGTQTP---TTVLITTTTTMTPTPT-PTSTKSTTVTPITTTTTVTATPT 1626
               T    P PT  + P   TT     TT   P PT P  T  TT   +T TT     PT
Sbjct: 535  PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 594

Query: 1627 PTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRS 1686
                  PT  P     T    PTPTT     PT                P+++ P T + 
Sbjct: 595  TPEKPAPTT-PEELAPTTPEEPTPTTPEEPAPT---------------TPKAAAPNTPKE 638

Query: 1687 TSSPLTESTTLLSTLPPAIEMTSTAPPSTP--TAPTTTSGGHTLSPPPSTTTSPPG---- 1740
             +    +     +   PA        P+TP  TAPT      TL  P  TT   P     
Sbjct: 639  PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKEL 692

Query: 1741 --TPTRGTTTGSSSAPTPSTVQ-TTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCV 1797
              T T+  T+ +   P P+T + T  T+   P PT    P+   TT     P+++     
Sbjct: 693  APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA--PTTPKGTAPTTLKEPAP 750

Query: 1798 LNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTP-TPSKP 1856
                  AP E     T G T                 +    P+PT TP ++ P TP +P
Sbjct: 751  TTPKKPAPKELAPTTTKGPTS----------------TTSDKPAPT-TPKETAPTTPKEP 793

Query: 1857 S-STPSKP---TPGTKPPECPDFDPPRQENE 1883
            + +TP KP   TP T PP   +   P    E
Sbjct: 794  APTTPKKPAPTTPETPPPTTSEVSTPTTTKE 824



 Score =  185 bits (469), Expect = 6e-46
 Identities = 158/490 (32%), Positives = 196/490 (40%), Gaps = 27/490 (5%)

Query: 1298 TQPTTMTTTTTENPTPT----PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTG 1353
            T P  +  TT E PTPT    P  TT       TP     TTP     TT   P PT T 
Sbjct: 602  TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-TP 660

Query: 1354 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTT 1413
             +T  TTP  T  T    P PT  + P    +  TTT  PT T      PT TP  T  T
Sbjct: 661  KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT-TPKGTAPT 719

Query: 1414 VTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTP 1472
                P PT  + P  TTP  T  T    P PT  + P P  +  T+T  PT T +    P
Sbjct: 720  TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 779

Query: 1473 TTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPT 1532
            TT P  T  T    P PT  + P PT     T  TP PT +   TPT+T   TT   +P 
Sbjct: 780  TT-PKETAPTTPKEPAPTTPKKPAPT-----TPETPPPTTSEVSTPTTTKEPTTIHKSPD 833

Query: 1533 P-TPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVL 1591
              TP  +  PTP  +  +      PT   T+TP  T    TTT     T    +T  T  
Sbjct: 834  ESTPELSAEPTPKALENSPKEPGVPT---TKTPAATKPEMTTTAKDKTTERDLRT--TPE 888

Query: 1592 ITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPT 1651
             TT        T T+T+ TT + IT TTT   T T T   TP  I    TTT+ P  T T
Sbjct: 889  TTTAAPKMTKETATTTEKTTESKITATTT-QVTSTTTQDTTPFKITTLKTTTLAPKVT-T 946

Query: 1652 TGSTGPPTHTSTAP--IAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            T  T   T     P   A+        +++TP+  + T +P   ++T      P +    
Sbjct: 947  TKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRK-- 1004

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTP 1769
              P +TPT    TS    L+P      +   T TR   T +S     +        A   
Sbjct: 1005 --PKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1062

Query: 1770 TPTPLSTPSI 1779
            TP  L  P +
Sbjct: 1063 TPHMLLRPHV 1072



 Score =  167 bits (422), Expect = 2e-40
 Identities = 181/608 (29%), Positives = 227/608 (37%), Gaps = 98/608 (16%)

Query: 1367 TVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTSTPITTT--TTVTPTPTPTGT 1423
            T   T T    +  T+  ITT   + P P+ P  + T   T +T    TTV    T T  
Sbjct: 193  TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTN 252

Query: 1424 QTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTP---TGTQTPT-TTPITT 1479
            +  +T     TT+   T +   T A     +  TS V   PTP   T T+ P  TTP   
Sbjct: 253  KQTSTDGKEKTTSAKETQSIEKTSAKD---LAPTSKVLAKPTPKAETTTKGPALTTPKEP 309

Query: 1480 TTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQ 1539
            T T    P  T  + PTPT I +  T    P PT T++  +TP     T T  P PT  +
Sbjct: 310  TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 369

Query: 1540 TPTPT----PISTTTTVTPT----PTPTGTQTPT-TTPI--TTTTTVTPTPTPTGTQTPT 1588
             P PT    P  TTT   PT    P PT  + P  TTP     TT   PTPT      PT
Sbjct: 370  EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 429

Query: 1589 TVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTP 1648
            T     TT   P PT     + T TP     T    P PT T+ P     S TT   P P
Sbjct: 430  TKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKEPAPTTTKEP-----SPTTPKEPAP 483

Query: 1649 T-----PTTGSTGPPTHTSTAPI-----AELTTSNPPPESSTPQTSRSTSSPLTESTTLL 1698
            T     PTT     PT T +AP      +  TT  P P  +TP+    T+      TT  
Sbjct: 484  TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP--TTPKEPAPTTPKKPAPTTPK 541

Query: 1699 STLP-----PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR-GTTTGSSS 1752
               P     PA   T    P+TP  P  T+   T    P   T  P TP +   TT    
Sbjct: 542  EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT--PTTPEKLAPTTPEKP 599

Query: 1753 AP-TPSTVQTTTTSAWTPT----PTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGE 1807
            AP TP  +  TT    TPT    P P +  +    T   P P++             P E
Sbjct: 600  APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT-------------PKE 646

Query: 1808 EVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPS--STPSKPTP 1865
                                       + P  P+PT TP ++ PT  K +  +T  +P P
Sbjct: 647  PAP------------------------TTPKEPAPT-TPKETAPTTPKGTAPTTLKEPAP 681

Query: 1866 GT-KPPECPDFDPPRQENETWWLCDCFMATCKYNNTVEIVKVECEP----PPMPTCSNGL 1920
             T K P   +  P   +  T   CD    T     T      E  P     P PT   G 
Sbjct: 682  TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP-KGTAPTTPKEPAPTTPKEPAPTTPKGT 740

Query: 1921 QPVRVEDP 1928
             P  +++P
Sbjct: 741  APTTLKEP 748



 Score =  106 bits (264), Expect = 3e-22
 Identities = 135/555 (24%), Positives = 188/555 (33%), Gaps = 147/555 (26%)

Query: 1439 PTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPT 1498
            PT  P+  +AP P+  + T   T   +P       T  +  +  +T   + +  Q  + +
Sbjct: 69   PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 128

Query: 1499 AITTTTTVT---------------------------------PTPTP------------- 1512
            + +++++ T                                 PTP P             
Sbjct: 129  SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 188

Query: 1513 --------TGT----QTPTSTPITTTTTVTPTPT-PTGTQTPTPTPIST---TTTVTPTP 1556
                    T T    +  TS  ITT   + P P+ P  + T   T ++    TT  T   
Sbjct: 189  DFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKET 248

Query: 1557 TPTGTQTPT-----TTPITTTTTVTPT--------------PTPTGTQTPTTVLITTTTT 1597
            T T  QT T     TT    T ++  T              PTP    T     +TT   
Sbjct: 249  TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 308

Query: 1598 MTPT------------PTPTSTKSTTVTP----ITTTTTVTAT---PTPTGTQTPT-MIP 1637
             TPT            PTPT+ KS   TP     TTT +   T   P PT T+ P    P
Sbjct: 309  PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 368

Query: 1638 ISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTL 1697
                 T T  P PTT  + P T    AP      +   P+   P T +   +P T     
Sbjct: 369  KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE-PTPTTPKEPA 427

Query: 1698 LSTLPPA----IEMTSTAP----PSTPTAPTTTSGGHTLSPPPSTTTSP-PGTPTRGTTT 1748
             +T  PA     E   TAP    P+TP  P  T+      P P+TT  P P TP     T
Sbjct: 428  PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT---PKEPAPTTTKEPSPTTPKEPAPT 484

Query: 1749 GSSSAPTPSTVQTTTTSAWTPT----PTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYA 1804
             + SAPT +     TT+   PT    P+P +T     TT   P P++            A
Sbjct: 485  TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 544

Query: 1805 PGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPT 1864
            P                             + P  P+PT T   +  TP +P+ T  K T
Sbjct: 545  P-----------------------------TTPKEPAPTTTKKPAPTTPKEPAPTTPKET 575

Query: 1865 PGTKPPECPDFDPPR 1879
              T P +     P +
Sbjct: 576  APTTPKKLTPTTPEK 590



 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 85/271 (31%), Positives = 104/271 (38%), Gaps = 16/271 (5%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQT 1356
            V+ PTT    TT + +P   T   +  PTP         P   TT T     P  T T  
Sbjct: 816  VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 875

Query: 1357 PTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTSTPITTTT 1412
              TT     TT  T T  P  T  +T TTT  TT + +T T T  T T T  +TP   TT
Sbjct: 876  DKTTERDLRTTPETTTAAPKMT-KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 934

Query: 1413 TVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQAPTPTAITTTSTVTPTPT---PTG 1468
              T T  P  T T  T  ITTT  +  P  T       T +  TT     PT     PT 
Sbjct: 935  LKTTTLAPKVTTTKKT--ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 992

Query: 1469 TQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTT 1528
            T+ P T P       TPTP      T T   +  T+ +      T T+ P  TP +    
Sbjct: 993  TKKPKTMPRVRKPKTTPTPR---KMTSTMPELNPTSRIAEAMLQTTTR-PNQTPNSKLVE 1048

Query: 1529 VTP-TPTPTGTQTPTPTPISTTTTVTPTPTP 1558
            V P +    G +  TP  +       P  TP
Sbjct: 1049 VNPKSEDAGGAEGETPHMLLRPHVFMPEVTP 1079


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score =  232 bits (592), Expect = 3e-60
 Identities = 225/775 (29%), Positives = 292/775 (37%), Gaps = 114/775 (14%)

Query: 1160 TTRPSTLTTFTTITLPTTPTTFT----TTTTTTTPTSSTVLS--TTPKLCCLWSDWINED 1213
            T +  T T    +T P  PT  T     +TT   PT +T+ S  TTPK     +    + 
Sbjct: 332  TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP---APTTTKS 388

Query: 1214 HPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQ 1273
             P++  +     T +     P++    + K+P  +  +                     +
Sbjct: 389  APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP-------APTTPK 441

Query: 1274 KPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQS 1333
            KP    P                 T P   T TT + P PT      T    P PT+ + 
Sbjct: 442  KPAPTTPKE------------PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 489

Query: 1334 ---TTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1390
               TTP     TT   P PT T   +PTT      TT    PT T    PTTT    TT 
Sbjct: 490  PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 549

Query: 1391 VTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGTQAP 1449
              P+PT T    PT TP     T    P PT  + P  TTP     T T  P PT  + P
Sbjct: 550  KEPSPTTTKEPAPT-TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 608

Query: 1450 TPTAITTTSTVTP---TPT------PTGTQTPT-TTPITTTTTVTPTPTPTGTQTPTPT- 1498
             PT    T+  TP   TPT      PT  + P  TTP     T    PTPT  + P PT 
Sbjct: 609  APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT 668

Query: 1499 ------------AITT------TTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQT 1540
                        A TT      TT   P PT T  +T  +TP  T  T    P PT  + 
Sbjct: 669  PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-TPKETAPTTPKGTAPTTLKEPAPTTPKK 727

Query: 1541 PTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTVLITTTTTMT 1599
            P P  ++ TTT  PT T      PTT   T  TT   P PT      PTT   T  TT+ 
Sbjct: 728  PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK 787

Query: 1600 PTPTPTSTK---------STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTP 1650
              P PT+ K         +TT  P +TT+   A  TP  T   T  P     T    P P
Sbjct: 788  E-PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT--PKEPAPTTPKKPAP 844

Query: 1651 TTGSTGPPTHTSTAP---IAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 1707
            TT  T PPT +  +      E TT +  P+ STP+ S   +    E++     +P     
Sbjct: 845  TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP 904

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTT--GSSSAPTPSTVQTTTTS 1765
             +T P  T TA   T+     + P +TT +P  T    TTT   + S  T +T Q T+T+
Sbjct: 905  AATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTT 964

Query: 1766 AWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSL 1825
                TP  ++T   ++TT L P  ++        +    P E                  
Sbjct: 965  TQDTTPFKITT---LKTTTLAPKVTTTKKTITTTEIMNKPEE------------------ 1003

Query: 1826 SCTLEFYNWSCPSTPSPTPTPSK-STPTPSKPSSTPSKPTPGTKPPECPDFDPPR 1879
                        + P    T SK +TP P KP+  P KPT   KP   P    P+
Sbjct: 1004 -----------TAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPK 1047



 Score =  216 bits (550), Expect = 2e-55
 Identities = 199/615 (32%), Positives = 240/615 (39%), Gaps = 75/615 (12%)

Query: 1297 VTQPTTMTTTTTENPT-PTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQ 1355
            + +PT    TTT+ P   TP   T T    P  T+ +  TPT I +  T    P PT T+
Sbjct: 328  LAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 387

Query: 1356 TPTTTPI--TTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPT----PTPTGTQTPT-ST 1406
            +  TTP     TTT  P PT      PTTT  P  TTT   PT    P PT  + P  +T
Sbjct: 388  SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 447

Query: 1407 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPT-----AITT----- 1456
            P     T    PTPT  + P  T      T    P PT  + P PT     A TT     
Sbjct: 448  PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 507

Query: 1457 -TSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGT 1515
             T+T  P+PT      PTTT    TTT  P PT T +   TP   + TTT  P PT    
Sbjct: 508  PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 567

Query: 1516 QTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTP-TPTPTGTQTPTTTPITTTTT 1574
              PT TP     T    P PT  + P PT        TP  P PT   TP  T  TT   
Sbjct: 568  PAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT---TPKETAPTTPKK 623

Query: 1575 VTP-TPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTP 1633
            +TP TP      TP     TT   + PT     T +T   P  TT    A  TP      
Sbjct: 624  LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 683

Query: 1634 TMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPI-----AELTTSNPPPESSTPQTSR--- 1685
            T    + TT   P PT T   T P T   TAP      A  T   P P+   P T++   
Sbjct: 684  TPKEPAPTTPKEPAPT-TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 742

Query: 1686 STSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSG--GHTLSPPPSTTTSPPG--- 1740
            ST+      TT   T P   +  +   P  P APTT  G    TL  P  TT   P    
Sbjct: 743  STTCDKPAPTTPKGTAPTTPKEPAPTTPKEP-APTTPKGTAPTTLKEPAPTTPKKPAPKE 801

Query: 1741 ---TPTRGTTTGSSSAPTPST-VQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICC 1796
               T T+G T+ +S  P P+T  +T  T+   P PT    P+   TT   P P++     
Sbjct: 802  LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA--PTTPETPPPTT----- 854

Query: 1797 VLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTP--SPTPTPSKSTPTPS 1854
                       EV   T       ++ S             STP  S  PTP     +P 
Sbjct: 855  ----------SEVSTPTTTKEPTTIHKSPD----------ESTPELSAEPTPKALENSPK 894

Query: 1855 KPSSTPSKPTPGTKP 1869
            +P    +K    TKP
Sbjct: 895  EPGVPTTKTPAATKP 909



 Score =  214 bits (544), Expect = 1e-54
 Identities = 197/631 (31%), Positives = 240/631 (38%), Gaps = 75/631 (11%)

Query: 1285 LNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTP--TPTSTQSTTPTPITTT 1342
            +N E  V+  E  T     +T   E  T    T +   T      PTS     PTP   T
Sbjct: 278  VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET 337

Query: 1343 TTVTPT------PTPTGTQTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1394
            TT  P       PTPT  + P  TT    T TT+   PT      PTTT    TT   P 
Sbjct: 338  TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 397

Query: 1395 PTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAI 1454
            PT T    PT TP     T T  P PT T++  TTP     T    P PT  + P PT  
Sbjct: 398  PTTTKEPAPT-TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 456

Query: 1455 TTTSTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAI---TTTTTVTPTP 1510
               +  TP  P PT  +   TTP     T    P PT  + P PT       TTT  P+P
Sbjct: 457  KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 516

Query: 1511 TPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPIT 1570
            T      PT+T    TTT  P PT T +   TP   S TTT  P PT      PTT P  
Sbjct: 517  TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT-PKK 575

Query: 1571 TTTTVTPTPTPTGTQTP---TTVLITTTTTMTPTPT-PTSTKSTTVTPITTTTTVTATPT 1626
               T    P PT  + P   TT     TT   P PT P  T  TT   +T TT     PT
Sbjct: 576  PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 635

Query: 1627 PTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRS 1686
                  PT  P     T    PTPTT     PT                P+++ P T + 
Sbjct: 636  TPEKPAPTT-PEELAPTTPEEPTPTTPEEPAPT---------------TPKAAAPNTPKE 679

Query: 1687 TSSPLTESTTLLSTLPPAIEMTSTAPPSTP--TAPTTTSGGHTLSPPPSTTTSPPG---- 1740
             +    +     +   PA        P+TP  TAPT      TL  P  TT   P     
Sbjct: 680  PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKEL 733

Query: 1741 --TPTRGTTTGSSSAPTPSTVQ-TTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCV 1797
              T T+  T+ +   P P+T + T  T+   P PT    P+   TT     P+++     
Sbjct: 734  APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA--PTTPKGTAPTTLKEPAP 791

Query: 1798 LNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTP-TPSKP 1856
                  AP E     T G T                 +    P+PT TP ++ P TP +P
Sbjct: 792  TTPKKPAPKELAPTTTKGPTS----------------TTSDKPAPT-TPKETAPTTPKEP 834

Query: 1857 S-STPSKP---TPGTKPPECPDFDPPRQENE 1883
            + +TP KP   TP T PP   +   P    E
Sbjct: 835  APTTPKKPAPTTPETPPPTTSEVSTPTTTKE 865



 Score =  185 bits (469), Expect = 6e-46
 Identities = 158/490 (32%), Positives = 196/490 (40%), Gaps = 27/490 (5%)

Query: 1298 TQPTTMTTTTTENPTPT----PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTG 1353
            T P  +  TT E PTPT    P  TT       TP     TTP     TT   P PT T 
Sbjct: 643  TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-TP 701

Query: 1354 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTT 1413
             +T  TTP  T  T    P PT  + P    +  TTT  PT T      PT TP  T  T
Sbjct: 702  KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT-TPKGTAPT 760

Query: 1414 VTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTP 1472
                P PT  + P  TTP  T  T    P PT  + P P  +  T+T  PT T +    P
Sbjct: 761  TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 820

Query: 1473 TTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPT 1532
            TT P  T  T    P PT  + P PT     T  TP PT +   TPT+T   TT   +P 
Sbjct: 821  TT-PKETAPTTPKEPAPTTPKKPAPT-----TPETPPPTTSEVSTPTTTKEPTTIHKSPD 874

Query: 1533 P-TPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVL 1591
              TP  +  PTP  +  +      PT   T+TP  T    TTT     T    +T  T  
Sbjct: 875  ESTPELSAEPTPKALENSPKEPGVPT---TKTPAATKPEMTTTAKDKTTERDLRT--TPE 929

Query: 1592 ITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPT 1651
             TT        T T+T+ TT + IT TTT   T T T   TP  I    TTT+ P  T T
Sbjct: 930  TTTAAPKMTKETATTTEKTTESKITATTT-QVTSTTTQDTTPFKITTLKTTTLAPKVT-T 987

Query: 1652 TGSTGPPTHTSTAP--IAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709
            T  T   T     P   A+        +++TP+  + T +P   ++T      P +    
Sbjct: 988  TKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRK-- 1045

Query: 1710 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTP 1769
              P +TPT    TS    L+P      +   T TR   T +S     +        A   
Sbjct: 1046 --PKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1103

Query: 1770 TPTPLSTPSI 1779
            TP  L  P +
Sbjct: 1104 TPHMLLRPHV 1113



 Score =  167 bits (422), Expect = 2e-40
 Identities = 181/608 (29%), Positives = 227/608 (37%), Gaps = 98/608 (16%)

Query: 1367 TVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTSTPITTT--TTVTPTPTPTGT 1423
            T   T T    +  T+  ITT   + P P+ P  + T   T +T    TTV    T T  
Sbjct: 234  TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTN 293

Query: 1424 QTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTP---TGTQTPT-TTPITT 1479
            +  +T     TT+   T +   T A     +  TS V   PTP   T T+ P  TTP   
Sbjct: 294  KQTSTDGKEKTTSAKETQSIEKTSAKD---LAPTSKVLAKPTPKAETTTKGPALTTPKEP 350

Query: 1480 TTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQ 1539
            T T    P  T  + PTPT I +  T    P PT T++  +TP     T T  P PT  +
Sbjct: 351  TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 410

Query: 1540 TPTPT----PISTTTTVTPT----PTPTGTQTPT-TTPI--TTTTTVTPTPTPTGTQTPT 1588
             P PT    P  TTT   PT    P PT  + P  TTP     TT   PTPT      PT
Sbjct: 411  EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 470

Query: 1589 TVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTP 1648
            T     TT   P PT     + T TP     T    P PT T+ P     S TT   P P
Sbjct: 471  TKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKEPAPTTTKEP-----SPTTPKEPAP 524

Query: 1649 T-----PTTGSTGPPTHTSTAPI-----AELTTSNPPPESSTPQTSRSTSSPLTESTTLL 1698
            T     PTT     PT T +AP      +  TT  P P  +TP+    T+      TT  
Sbjct: 525  TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP--TTPKEPAPTTPKKPAPTTPK 582

Query: 1699 STLP-----PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR-GTTTGSSS 1752
               P     PA   T    P+TP  P  T+   T    P   T  P TP +   TT    
Sbjct: 583  EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT--PTTPEKLAPTTPEKP 640

Query: 1753 AP-TPSTVQTTTTSAWTPT----PTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGE 1807
            AP TP  +  TT    TPT    P P +  +    T   P P++             P E
Sbjct: 641  APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT-------------PKE 687

Query: 1808 EVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPS--STPSKPTP 1865
                                       + P  P+PT TP ++ PT  K +  +T  +P P
Sbjct: 688  PAP------------------------TTPKEPAPT-TPKETAPTTPKGTAPTTLKEPAP 722

Query: 1866 GT-KPPECPDFDPPRQENETWWLCDCFMATCKYNNTVEIVKVECEP----PPMPTCSNGL 1920
             T K P   +  P   +  T   CD    T     T      E  P     P PT   G 
Sbjct: 723  TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP-KGTAPTTPKEPAPTTPKEPAPTTPKGT 781

Query: 1921 QPVRVEDP 1928
             P  +++P
Sbjct: 782  APTTLKEP 789



 Score =  106 bits (264), Expect = 3e-22
 Identities = 135/555 (24%), Positives = 188/555 (33%), Gaps = 147/555 (26%)

Query: 1439 PTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPT 1498
            PT  P+  +AP P+  + T   T   +P       T  +  +  +T   + +  Q  + +
Sbjct: 110  PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 169

Query: 1499 AITTTTTVT---------------------------------PTPTP------------- 1512
            + +++++ T                                 PTP P             
Sbjct: 170  SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 229

Query: 1513 --------TGT----QTPTSTPITTTTTVTPTPT-PTGTQTPTPTPIST---TTTVTPTP 1556
                    T T    +  TS  ITT   + P P+ P  + T   T ++    TT  T   
Sbjct: 230  DFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKET 289

Query: 1557 TPTGTQTPT-----TTPITTTTTVTPT--------------PTPTGTQTPTTVLITTTTT 1597
            T T  QT T     TT    T ++  T              PTP    T     +TT   
Sbjct: 290  TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 349

Query: 1598 MTPT------------PTPTSTKSTTVTP----ITTTTTVTAT---PTPTGTQTPT-MIP 1637
             TPT            PTPT+ KS   TP     TTT +   T   P PT T+ P    P
Sbjct: 350  PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 409

Query: 1638 ISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTL 1697
                 T T  P PTT  + P T    AP      +   P+   P T +   +P T     
Sbjct: 410  KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE-PTPTTPKEPA 468

Query: 1698 LSTLPPA----IEMTSTAP----PSTPTAPTTTSGGHTLSPPPSTTTSP-PGTPTRGTTT 1748
             +T  PA     E   TAP    P+TP  P  T+      P P+TT  P P TP     T
Sbjct: 469  PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT---PKEPAPTTTKEPSPTTPKEPAPT 525

Query: 1749 GSSSAPTPSTVQTTTTSAWTPT----PTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYA 1804
             + SAPT +     TT+   PT    P+P +T     TT   P P++            A
Sbjct: 526  TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 585

Query: 1805 PGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPT 1864
            P                             + P  P+PT T   +  TP +P+ T  K T
Sbjct: 586  P-----------------------------TTPKEPAPTTTKKPAPTTPKEPAPTTPKET 616

Query: 1865 PGTKPPECPDFDPPR 1879
              T P +     P +
Sbjct: 617  APTTPKKLTPTTPEK 631



 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 85/271 (31%), Positives = 104/271 (38%), Gaps = 16/271 (5%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQT 1356
            V+ PTT    TT + +P   T   +  PTP         P   TT T     P  T T  
Sbjct: 857  VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 916

Query: 1357 PTTTP---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTSTPITTTT 1412
              TT     TT  T T  P  T  +T TTT  TT + +T T T  T T T  +TP   TT
Sbjct: 917  DKTTERDLRTTPETTTAAPKMT-KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 975

Query: 1413 TVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQAPTPTAITTTSTVTPTPT---PTG 1468
              T T  P  T T  T  ITTT  +  P  T       T +  TT     PT     PT 
Sbjct: 976  LKTTTLAPKVTTTKKT--ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 1033

Query: 1469 TQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTT 1528
            T+ P T P       TPTP      T T   +  T+ +      T T+ P  TP +    
Sbjct: 1034 TKKPKTMPRVRKPKTTPTPR---KMTSTMPELNPTSRIAEAMLQTTTR-PNQTPNSKLVE 1089

Query: 1529 VTP-TPTPTGTQTPTPTPISTTTTVTPTPTP 1558
            V P +    G +  TP  +       P  TP
Sbjct: 1090 VNPKSEDAGGAEGETPHMLLRPHVFMPEVTP 1120


>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
          Length = 5405

 Score =  228 bits (582), Expect = 5e-59
 Identities = 218/797 (27%), Positives = 313/797 (39%), Gaps = 119/797 (14%)

Query: 367  VLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQ 426
            V +N + + LP V A+  + R S +   V +     L+V    V  + VT+      Q+ 
Sbjct: 1329 VTVNGVDMKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMC 1387

Query: 427  GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDP-----------C 475
            GLCGN+NG   DDF+  +G        F N+W+        L     P           C
Sbjct: 1388 GLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKC 1447

Query: 476  SLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSS 535
               +E     E +C LL     P   CH  VDP    K C +D C    N   LC+ + +
Sbjct: 1448 PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHA 1507

Query: 536  YARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFA 594
            Y  AC A G  +  WR E  C  +   CP +  +     TC   C +LS A   C +G A
Sbjct: 1508 YVSACQAAGGHVEPWRTETFCPME---CPPNSHYELCADTCSLGCSALS-APPQCQDGCA 1563

Query: 595  PVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV--RQEERCVCRDGRLHCRQ 652
              +GC C D  FL     CVP+ +C CYH G+Y E    V+     ++C C  G      
Sbjct: 1564 --EGCQC-DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAG------ 1614

Query: 653  IRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVC-PDGLMDDG 711
                                        + + CQ          C  G VC P G    G
Sbjct: 1615 ----------------------------KGMVCQ-------EHSCKPGQVCQPSG----G 1635

Query: 712  RGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYIT 771
               CV +  C           G   +    TC  + G+ VC       TC ++G  HY +
Sbjct: 1636 ILSCVTKDPC----------HGVTCRPQ-ETCKEQGGQGVCLPNY-EATCWLWGDPHYHS 1683

Query: 772  FDGKYYDFDGHCSYVAVQDYCGQNSSLG--SFSIITENVPCGTTGVTCSKAIKIFMGRTE 829
            FDG+ +DF G C+YV     C   S+ G   F++ T+N   G   V+  + + +    T 
Sbjct: 1684 FDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTN 1743

Query: 830  LKLEDKHRVVIQRDEGHHVAY----------TTREVGQYLVVESSTGIIVIWDKRTTVFI 879
            + +  K  +   R  G   A            T+   + L+V +  G+ V +D    V +
Sbjct: 1744 ISIH-KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV-ADFGLQVSYDWNWRVDV 1801

Query: 880  KLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDVSTNPE 936
             L  SY G VCGLCGN D   NND    +  +  S   +G SW+     P C D      
Sbjct: 1802 TLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC 1861

Query: 937  P-CSLNPHRRSWAEKQCSILKSSV---FSICHSKVDPKPFYEACVHDSCSCDTGGDCECF 992
            P C  +   +      C  L       F+ CH+ V P+ F++ CV D C    GGD +  
Sbjct: 1862 PTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDIL 1919

Query: 993  CSAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTING 1051
            C A+ASY   C   G  +  WR    C I C   +       HYE CG+    +C +   
Sbjct: 1920 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGSPCPASCPSPAP 1972

Query: 1052 IHSNISVSYLEG-CYPRCPKDRPIYEEDLKKCVTADK-CGCYVEDTHYPPGASVPTEETC 1109
            +    + +  EG C   C  D   +     +CV  +  CGC+   T++  G+    + TC
Sbjct: 1973 L---TTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTC 2028

Query: 1110 KS-CVC-TNSSQVVCRP 1124
               C C      +VC P
Sbjct: 2029 SQWCRCGPGGGSLVCTP 2045



 Score =  228 bits (580), Expect = 8e-59
 Identities = 218/796 (27%), Positives = 313/796 (39%), Gaps = 117/796 (14%)

Query: 367  VLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQ 426
            V +N + + LP V A+  + R S +   V +     L+V    V  + VT+       + 
Sbjct: 3731 VTVNGVDMKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMC 3789

Query: 427  GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKA---QSSCHDKLDWL--------DDPC 475
            GLCGN+NG   DDF+  +G        F N+W+     S C                D C
Sbjct: 3790 GLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKC 3849

Query: 476  SLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSS 535
               +E     E +C LL     P   CH  VDP    K C +D C    N   LC+ + +
Sbjct: 3850 PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHA 3909

Query: 536  YARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFA 594
            Y  AC A G  +  WR E  C  +   CP +  +     TC   C +LS A   C +G A
Sbjct: 3910 YVSACQAAGGHVEPWRNETFCPME---CPQNSHYELCADTCSLGCSALS-APLQCPDGCA 3965

Query: 595  PVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV--RQEERCVCRDGRLHCRQ 652
              +GC C D  FL     CVP+ +C CYH G+Y E    V+     ++C C  G++    
Sbjct: 3966 --EGCQC-DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKV---- 4018

Query: 653  IRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVC-PDGLMDDG 711
                                          + CQ          C  G VC P G    G
Sbjct: 4019 ------------------------------VVCQ-------EHSCKPGQVCQPSG----G 4037

Query: 712  RGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYIT 771
               CV +  C           G   +    TC  + G+ VC       TC ++G  HY +
Sbjct: 4038 ILSCVTKDPC----------HGVTCRPQ-ETCKEQGGQGVCLPNY-EATCWLWGDPHYHS 4085

Query: 772  FDGKYYDFDGHCSYVAVQDYCGQNSSLG--SFSIITENVPCGTTGVTCSKAIKIFMGRTE 829
            FDG+ +DF G C+YV     C   S+ G   F++ T+N   G   V+  + + +    T 
Sbjct: 4086 FDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTN 4145

Query: 830  LKLEDKHRVVIQRDEGHHVAYTTREV-GQYLVVESST--------GIIVIWDKRTTVFIK 880
            + +  K  +   R  G   A       G+  V + ++        G+ V +D    V + 
Sbjct: 4146 ISIH-KDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVT 4204

Query: 881  LAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDVSTNPEP 937
            L  SY G VCGLCGN D   NND    +  +  S   +G SW+     P C D      P
Sbjct: 4205 LPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP 4264

Query: 938  -CSLNPHRRSWAEKQCSILKSSV---FSICHSKVDPKPFYEACVHDSCSCDTGGDCECFC 993
             C  +   +      C  L S     F+ CH+ V P+ F++ CV D C    GGD +  C
Sbjct: 4265 TCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDILC 4322

Query: 994  SAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGI 1052
             A+ASY   C   G  +  WR    C I C   +       HYE CG     +C +   +
Sbjct: 4323 KALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPASCPSPAPL 4375

Query: 1053 HSNISVSYLEG-CYPRCPKDRPIYEEDLKKCVTADK-CGCYVEDTHYPPGASVPTEETCK 1110
                + +  EG C   C  D   +     +CV  +  CGC+   T++  G+    + TC 
Sbjct: 4376 ---TTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCS 4431

Query: 1111 S-CVC-TNSSQVVCRP 1124
              C C      +VC P
Sbjct: 4432 QWCRCGPGGGSLVCTP 4447



 Score =  224 bits (570), Expect = 1e-57
 Identities = 213/796 (26%), Positives = 314/796 (39%), Gaps = 117/796 (14%)

Query: 367  VLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQ 426
            V +N + + LP V A+  + R S +   V +     L+V    V  + VT+       + 
Sbjct: 2530 VTVNGVDMKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMC 2588

Query: 427  GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKA---------QSSCHDKLDWL--DDPC 475
            GLCGN+NG   DDF+  +G        F N+W+            +C    +     + C
Sbjct: 2589 GLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEEC 2648

Query: 476  SLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSS 535
               +E     E +C LL     P   CH  VDP    K C +D C    N   LC+ + +
Sbjct: 2649 PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHA 2708

Query: 536  YARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFA 594
            Y  AC A G  +  WR E  C  +   CP +  +     TC   C +LS A   C +G A
Sbjct: 2709 YVSACQAAGGQVEPWRNETFCPME---CPQNSHYELCADTCSLGCSALS-APLQCPDGCA 2764

Query: 595  PVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV--RQEERCVCRDGRLHCRQ 652
              +GC C D  FL     CVP+ +C CYH G Y E    V+     ++C C  G++    
Sbjct: 2765 --EGCQC-DSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKV---- 2817

Query: 653  IRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGR 712
                                          + CQ          C  G VC         
Sbjct: 2818 ------------------------------VVCQ-------EHSCKPGQVCQPS------ 2834

Query: 713  GGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITF 772
            GG +      CV+ +  +    + +    TC  + G+ VC       TC ++G  HY +F
Sbjct: 2835 GGIL-----SCVNKDPCHGVTCRPQ---ETCKEQGGQGVCLPNY-EATCWLWGDPHYHSF 2885

Query: 773  DGKYYDFDGHCSYVAVQDYCGQNSSLG--SFSIITENVPCGTTGVTCSKAIKIFMGRTEL 830
            DG+ +DF G C+YV     C   S+ G   F++ T+N   G   V+  + + +    T +
Sbjct: 2886 DGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNI 2945

Query: 831  KLEDKHRVVIQRDEGHHVAY----------TTREVGQYLVVESSTGIIVIWDKRTTVFIK 880
             +  K  +   R  G   A            T+   + L+V +  G+ V +D    V + 
Sbjct: 2946 SIH-KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV-ADFGLQVSYDWNWRVDVT 3003

Query: 881  LAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDVSTNPEP 937
            L  SY G VCGLCGN D   NND    +  +  S   +G SW+     P C D      P
Sbjct: 3004 LPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP 3063

Query: 938  -CSLNPHRRSWAEKQCSILKSSV---FSICHSKVDPKPFYEACVHDSCSCDTGGDCECFC 993
             C  +   +      C  L       F+ CH+ V P+ F++ CV D C    GGD +  C
Sbjct: 3064 TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDILC 3121

Query: 994  SAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGI 1052
             A+ASY   C   G  +  WR    C I C   +       HYE CG     +C +   +
Sbjct: 3122 KALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPASCPSPAPL 3174

Query: 1053 HSNISVSYLEG-CYPRCPKDRPIYEEDLKKCVTADK-CGCYVEDTHYPPGASVPTEETCK 1110
                + +  EG C   C  D   +     +CV  +  CGC+   T++  G+    + TC 
Sbjct: 3175 ---TTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCS 3230

Query: 1111 S-CVC-TNSSQVVCRP 1124
              C C      +VC P
Sbjct: 3231 QWCRCGPGGGSLVCTP 3246



 Score =  205 bits (522), Expect = 4e-52
 Identities = 181/720 (25%), Positives = 278/720 (38%), Gaps = 144/720 (20%)

Query: 427  GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAE 486
            GLCGN+N    DD K   G       G A   +    C  K      PC+   + +    
Sbjct: 4611 GLCGNYNQDPADDLKAVGGKPAGWQVGGA---QGCGECVSKP--CPSPCTPEQQESFGGP 4665

Query: 487  HWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVM 546
              C ++  T+ P   CH  V PA+Y++ C  D C  Q +   LC A+++Y  AC A G  
Sbjct: 4666 DACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQ 4725

Query: 547  LWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFAPVDGCGCP 602
            L  WR    C      CP    +     +C  +C SLS     +S C E      GC C 
Sbjct: 4726 LGEWRRPDFCPL---QCPAHSHYELCGDSCPVSCPSLSAPEGCESACRE------GCVC- 4775

Query: 603  DHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV---RQEERCVCRDGRLHCRQIRLIGQS 659
            D  F+     CVP+ +C C H G Y   G+V       E RC C  G             
Sbjct: 4776 DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPG------------- 4822

Query: 660  CTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEK 719
                                   ++CQ  AA   H EC          ++DG   C    
Sbjct: 4823 ---------------------GHVTCQEGAACGPHEEC---------RLEDGVQAC---- 4848

Query: 720  ECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDF 779
                      +++G      C  C    G                   HYIT DG+ YD 
Sbjct: 4849 ----------HATG------CGRCLANGGI------------------HYITLDGRVYDL 4874

Query: 780  DGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVV 839
             G CSYV  Q  C        FSI+ E    G       + + + +    + L    +V 
Sbjct: 4875 HGSCSYVLAQ-VCHPKPGDEDFSIVLEKNAAGDL-----QRLLVTVAGQVVSLAQGQQVT 4928

Query: 840  IQRDEGHHVAY--------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCG 891
            +   +G  VA          T E G+ +V++++ G+ +++D    + + +   ++G +CG
Sbjct: 4929 V---DGEAVALPVAVGRVRVTAE-GRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCG 4984

Query: 892  LCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEP-----CSLNPHRRS 946
            LCGNF+   ++DF   +    SS   FG +W+   +         P     C        
Sbjct: 4985 LCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPY 5044

Query: 947  WAEKQCSILKS--SVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECT 1004
             + + C  L++    F+ C + + P  ++  CV+D C+    GD    C ++A+Y   C 
Sbjct: 5045 ESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQ 5102

Query: 1005 KEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEG 1063
              G  V  WRT   CP+ C    P H    HY  C      +C  ++G+ +  +    EG
Sbjct: 5103 AAGVAVKPWRTDSFCPLHC----PAHS---HYSICTRTCQGSCAALSGL-TGCTTRCFEG 5154

Query: 1064 CYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCR 1123
            C   C  DR +  + +  C+    CGC     + P  +S+ T +  + C C++SS + C+
Sbjct: 5155 C--EC-DDRFLLSQGV--CIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 5209



 Score =  180 bits (456), Expect = 2e-44
 Identities = 137/466 (29%), Positives = 206/466 (44%), Gaps = 57/466 (12%)

Query: 697  CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--------CN------T 742
            CV GCVC  G +  G G CV    C C       + G ++  D        CN      T
Sbjct: 776  CVEGCVCLPGFVASG-GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVT 834

Query: 743  C----TCKRGRWVCTQ---AVCH----GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 791
            C    +C  G     Q     C+    GTC   G  HY++FDG+ +DF G C+Y+ V   
Sbjct: 835  CRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS- 893

Query: 792  CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHR-VVIQRDEGHHVAY 850
            CGQN++L +F ++ EN   G+  V+ ++A+++     ++ +  ++   V+  D   ++ +
Sbjct: 894  CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPF 953

Query: 851  TTRE-------VGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 903
               +        G+  VV +  G+ V +D    V  K+  SY   +CGLCGNF+    +D
Sbjct: 954  QAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1013

Query: 904  FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPH---RRSWAEKQCSIL--KSS 958
               R     ++ L FGNSW+E       +T P  C        ++  ++ +C IL     
Sbjct: 1014 LALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKG 1073

Query: 959  VFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDL 1017
             F  CHSK+DP+     CV+D C     G     C A+A+YA  C   GA V  WR+ +L
Sbjct: 1074 PFRECHSKLDPQGAVRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEEL 1131

Query: 1018 CPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEE 1077
            CP+ C    PPH    HYE C      +C  +  +         EGC   C +   +  E
Sbjct: 1132 CPLSC----PPHS---HYEACSYGCPLSCGDL-PVPGGCGSECHEGCV--CDEGFALSGE 1181

Query: 1078 DLKKCVTADKCGCYVEDTHYPPGASVPTEETCKS-CVCTNSSQVVC 1122
                C+    CGC  + T++PPG +      C S C C     V C
Sbjct: 1182 ---SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1224



 Score =  177 bits (448), Expect = 2e-43
 Identities = 156/597 (26%), Positives = 228/597 (38%), Gaps = 102/597 (17%)

Query: 684  SCQTLAAGY-YHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--C 740
            SC +L+A     + C  GCVC  G +  G   CV   +C C+H++  Y  G        C
Sbjct: 2353 SCPSLSAPEGCESACREGCVCDAGFVLSG-DTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 2411

Query: 741  NT-CTCKRGRWVCTQ--------------------AVCHGTCSIYGSGHYITFDGKYYDF 779
            ++ C C+ G  V  +                    AV   TC   G  HY TFDG+ +DF
Sbjct: 2412 DSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDF 2471

Query: 780  DGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVV 839
             G C YV  Q  CG    L  F+++ ENV  G   V+ ++ I + +    L+LE +   V
Sbjct: 2472 MGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKV 2530

Query: 840  IQR--DEGHHVAYTTREV-----GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGL 892
                 D    V     ++     G  +V+E+  G+ V +D    V + +  +Y   +CGL
Sbjct: 2531 TVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGL 2590

Query: 893  CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---------PTCPDVSTN---PEPCSL 940
            CGN++    +DF   +     +  +FGNSW+E          PTCP  S      E C  
Sbjct: 2591 CGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPP 2650

Query: 941  NPHRRSWAEKQCSILKSSV--FSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVAS 998
               ++   E+ C +L S     S CH  VDP+   + C+ D C    GG+    CS + +
Sbjct: 2651 ELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHA 2708

Query: 999  YAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNIS 1057
            Y   C   G  V  WR    CP+ C   +       HYE C +     C  ++       
Sbjct: 2709 YVSACQAAGGQVEPWRNETFCPMECPQNS-------HYELCADTCSLGCSALSA-----P 2756

Query: 1058 VSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNS 1117
            +   +GC   C  D        + CV   +CGCY    +Y P  +V  +   + C C   
Sbjct: 2757 LQCPDGCAEGCQCDSGFLYNG-QACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVG 2815

Query: 1118 SQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFN---ICSITTRPSTLTTFTTITL 1174
              VVC+    K             ++C P+G +    N      +T RP           
Sbjct: 2816 KVVVCQEHSCK-----------PGQVCQPSGGILSCVNKDPCHGVTCRPQ---------- 2854

Query: 1175 PTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDGVC 1231
                      T          L      C LW D      P   S DG +  F G C
Sbjct: 2855 ---------ETCKEQGGQGVCLPNYEATCWLWGD------PHYHSFDGRKFDFQGTC 2896



 Score =  176 bits (447), Expect = 2e-43
 Identities = 173/675 (25%), Positives = 248/675 (36%), Gaps = 105/675 (15%)

Query: 604  HTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLH-CRQIRLIGQSCTA 662
            H+ LD +G         C   G      D +      C      +H  R   L   SC  
Sbjct: 1079 HSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP- 1137

Query: 663  PKIHMDCSNLTALATSKPRALSCQTLAA-GYYHTECVSGCVCPDGLMDDGRGGCVVEKEC 721
            P  H +       A S    LSC  L   G   +EC  GCVC +G    G   C+    C
Sbjct: 1138 PHSHYE-------ACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGES-CLPLASC 1189

Query: 722  PCVHNNDLYSSGAKIKVD--CNT-CTCKRGRWVCTQ--------------------AVCH 758
             CVH    +  G        C++ C C+ G  V  +                    AV  
Sbjct: 1190 GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGS 1249

Query: 759  GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCS 818
             TC   G  HY TFDG+ +DF G C YV  Q  CG    L  F+++ ENV  G   V+ +
Sbjct: 1250 STCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVT 1308

Query: 819  KAIKIFMGRTELKLEDKHRVVIQR--DEGHHVAYTTREV-----GQYLVVESSTGIIVIW 871
            + I + +    L+LE +   V     D    V     ++     G  +V+E+  G+ V +
Sbjct: 1309 RVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY 1368

Query: 872  DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE-APTCPD 930
            D    V + +  +Y   +CGLCGN++    +DF   +     +  +FGNSW+E  P  P 
Sbjct: 1369 DLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC 1428

Query: 931  VSTNPEP-----------CSLNPHRRSWAEKQCSILKSSV--FSICHSKVDPKPFYEACV 977
            +   P P           C     ++   E+ C +L S     S CH  VDP+   + C+
Sbjct: 1429 LPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCI 1488

Query: 978  HDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYE 1036
             D C    GG+    CS + +Y   C   G  V  WRT   CP+ C    PP+    HYE
Sbjct: 1489 FDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC----PPNS---HYE 1539

Query: 1037 PCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTH 1096
             C +     C  ++           +GC   C  D        + CV   +CGCY    +
Sbjct: 1540 LCADTCSLGCSALSA-----PPQCQDGCAEGCQCDSGFLYNG-QACVPIQQCGCYHNGVY 1593

Query: 1097 YPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNI 1156
            Y P  +V  +   + C C     +VC+    K             ++C P+G +     +
Sbjct: 1594 YEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCK-----------PGQVCQPSGGI-----L 1637

Query: 1157 CSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPS 1216
              +T  P    T                T          L      C LW D      P 
Sbjct: 1638 SCVTKDPCHGVTCR-----------PQETCKEQGGQGVCLPNYEATCWLWGD------PH 1680

Query: 1217 SGSDDGDRETFDGVC 1231
              S DG +  F G C
Sbjct: 1681 YHSFDGRKFDFQGTC 1695



 Score =  174 bits (441), Expect = 1e-42
 Identities = 155/594 (26%), Positives = 227/594 (38%), Gaps = 96/594 (16%)

Query: 684  SCQTLAAGY-YHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--C 740
            SC +L+A     + C  GCVC  G +  G   CV   +C C+H++  Y  G        C
Sbjct: 3554 SCPSLSAPEGCESACREGCVCDAGFVLSG-DTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 3612

Query: 741  NT-CTCKRGRWVCTQ--------------------AVCHGTCSIYGSGHYITFDGKYYDF 779
            ++ C C+ G  V  +                    AV   TC   G  HY TFDG  +DF
Sbjct: 3613 DSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDF 3672

Query: 780  DGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVV 839
             G C YV  Q  CG    L  F+++ ENV  G   V+ ++ I + +    L+LE +   V
Sbjct: 3673 MGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKV 3731

Query: 840  IQR--DEGHHVAYTTREV-----GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGL 892
                 D    V     ++     G  +V+E+  G+ V +D    V + +  +Y   +CGL
Sbjct: 3732 TVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGL 3791

Query: 893  CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---------PTCPDVSTNPEP---CSL 940
            CGN++    +DF   +     +  +FGNSW+E          PTCP  S    P   C  
Sbjct: 3792 CGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPP 3851

Query: 941  NPHRRSWAEKQCSILKSSV--FSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVAS 998
               ++   E+ C +L S     S CH  VDP+   + C+ D C    GG+    CS + +
Sbjct: 3852 ELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHA 3909

Query: 999  YAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNIS 1057
            Y   C   G  V  WR    CP+ C   +       HYE C +     C  ++       
Sbjct: 3910 YVSACQAAGGHVEPWRNETFCPMECPQNS-------HYELCADTCSLGCSALSA-----P 3957

Query: 1058 VSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNS 1117
            +   +GC   C  D        + CV   +CGCY    +Y P  +V  +   + C C   
Sbjct: 3958 LQCPDGCAEGCQCDSGFLYNG-QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVG 4016

Query: 1118 SQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPTT 1177
              VVC+    K             ++C P+G +     +  +T  P    T         
Sbjct: 4017 KVVVCQEHSCK-----------PGQVCQPSGGI-----LSCVTKDPCHGVTCR------- 4053

Query: 1178 PTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDGVC 1231
                   T          L      C LW D      P   S DG +  F G C
Sbjct: 4054 ----PQETCKEQGGQGVCLPNYEATCWLWGD------PHYHSFDGRKFDFQGTC 4097



 Score =  160 bits (404), Expect = 2e-38
 Identities = 118/404 (29%), Positives = 178/404 (44%), Gaps = 39/404 (9%)

Query: 743  CTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFS 802
            C    G+  C  A     C   G  HY TFDG+ YD  G CSY  V+  C ++ +L +FS
Sbjct: 455  CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFS 512

Query: 803  IITENVPCGTTGVTC---------SKAIKIFMGRTELKLED--KHRVVIQRDEGHHVAYT 851
            +  +N   G+  V+          S ++ +  G     L D  + R+ +   EG    Y 
Sbjct: 513  VEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572

Query: 852  TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMV 911
            +   G   VVE   G++V +D    + + L   ++  VCGLCGN++    +DF T D  +
Sbjct: 573  S---GPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGAL 629

Query: 912  VSSELDFGNSWKEAP---TCPDVSTNPEP-CSLNPHRRSWAEKQCSILK--SSVFSICHS 965
                ++F +SWK       C D   N  P C+    +    ++ C +L      F++CH 
Sbjct: 630  APDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 689

Query: 966  KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDY 1024
             +DP+PF E CV+D C    GG+    C  +++YAQ C + G  V  WR+P  CP+ C  
Sbjct: 690  TLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC-- 745

Query: 1025 YNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVT 1084
                      YE CG     +C       +      +EGC   C    P +      CV 
Sbjct: 746  -----PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCV--C---LPGFVASGGACVP 795

Query: 1085 ADKCGCYVEDTHYPPGASVPTEETC-KSCVCTNSS-QVVCRPEE 1126
            A  CGC  +     PG  V  +E C + C C  ++ QV CR ++
Sbjct: 796  ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ 839



 Score =  144 bits (364), Expect = 9e-34
 Identities = 119/470 (25%), Positives = 189/470 (40%), Gaps = 67/470 (14%)

Query: 697  CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCT--CK----RGRW 750
            CV GC C  G +        +   C C  N   + +G++   D  TC+  C+     G  
Sbjct: 3184 CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWAD-GTCSQWCRCGPGGGSL 3242

Query: 751  VCTQAVC-------------HGT-------CSIYGSGHYITFDGKYYDFDGHCSYVAVQD 790
            VCT A C             HG        C  +G  HY+T DG  +DF G C Y+    
Sbjct: 3243 VCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 3302

Query: 791  YCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAY 850
              G      +F++   N   G+  V+ ++++ + +    L L  +    +Q D G  V  
Sbjct: 3303 CHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD-GVFVTL 3361

Query: 851  T--------TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNN 902
                         G  +VV +++G+ + +D  + V +++  +Y G++CGLCGN++    +
Sbjct: 3362 PFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPAD 3421

Query: 903  DFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSS--VF 960
            D           ++       E  + P     P PC+            C ++ ++    
Sbjct: 3422 DLKAVGGKPAGWQVGGAQGCGECVSKP----CPSPCTPEQQESFGGPDACGVISATDGPL 3477

Query: 961  SICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCP 1019
            + CH  V P  +++ C+ D+C     G     C AVA+Y   C   GA +  WR PD CP
Sbjct: 3478 APCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCP 3535

Query: 1020 IFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDL 1079
              C    P H    HYE CG+    +C          S+S  EGC   C ++  + +   
Sbjct: 3536 FQC----PAHS---HYELCGDSCPGSCP---------SLSAPEGCESAC-REGCVCDAGF 3578

Query: 1080 ----KKCVTADKCGCYVEDTHYPPGASVPTEETCKS-CVCTNSSQVVCRP 1124
                  CV   +CGC  +D +YP G +      C S C C    +V C P
Sbjct: 3579 VLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEP 3628



 Score =  143 bits (361), Expect = 2e-33
 Identities = 126/513 (24%), Positives = 204/513 (39%), Gaps = 73/513 (14%)

Query: 656  IGQSCTAPK-IHMD-CSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRG 713
            +G   T P+  H + C +    +   P  L+   +  G     CV GC C  G +     
Sbjct: 1944 VGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEG----PCVEGCQCDAGFVLSADR 1999

Query: 714  GCVVEKECPCVHNNDLYSSGAKIKVDCNTCT--CK----RGRWVCTQAVC---------- 757
               +   C C  N   + +G++   D  TC+  C+     G  VCT A C          
Sbjct: 2000 CVPLNNGCGCWANGTYHEAGSEFWAD-GTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLP 2058

Query: 758  ---HGT-------CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITEN 807
               HG        C  +G  HY+T DG  ++F G C Y+      G      +F++   N
Sbjct: 2059 SGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVAN 2118

Query: 808  VPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT--------TREVGQYL 859
               G+  V+ ++++ + +    L L  +    +Q D G  V               G  +
Sbjct: 2119 EHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD-GVFVTLPFQLDSLLHAHLSGADV 2177

Query: 860  VVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFG 919
            VV +++G+ + +D  + V +++  +Y G++CGLCGN++    +D           ++   
Sbjct: 2178 VVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA 2237

Query: 920  NSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSS--VFSICHSKVDPKPFYEACV 977
                E  + P     P PC+            C ++ ++    + CH  V P  +++ C+
Sbjct: 2238 QGCGECVSKP----CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 2293

Query: 978  HDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYE 1036
             D+C     G     C AVA+Y   C   GA +  WR PD CP  C    P H    HYE
Sbjct: 2294 LDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQC----PAHS---HYE 2344

Query: 1037 PCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDL----KKCVTADKCGCYV 1092
             CG+    +C          S+S  EGC   C ++  + +         CV   +CGC  
Sbjct: 2345 LCGDSCPGSCP---------SLSAPEGCESAC-REGCVCDAGFVLSGDTCVPVGQCGCLH 2394

Query: 1093 EDTHYPPGASVPTEETCKS-CVCTNSSQVVCRP 1124
            +D +YP G +      C S C C    +V C P
Sbjct: 2395 DDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEP 2427



 Score =  139 bits (350), Expect = 4e-32
 Identities = 121/485 (24%), Positives = 192/485 (39%), Gaps = 78/485 (16%)

Query: 697  CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCT--CK----RGRW 750
            CV GC C  G +        +   C C  N   + +G++   D  TC+  C+     G  
Sbjct: 4385 CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWAD-GTCSQWCRCGPGGGSL 4443

Query: 751  VCTQAVC-------------HGT-------CSIYGSGHYITFDGKYYDFDGHCSYVAVQD 790
            VCT A C             HG        C  +G  HY+T DG  +DF G C Y+    
Sbjct: 4444 VCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 4503

Query: 791  YCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAY 850
              G      +F++   N   G+  V+ ++++ + +    L L  +    +Q D G  VA 
Sbjct: 4504 CHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD-GVFVAL 4562

Query: 851  T--------TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNN 902
                         G  +VV +++G+ + +D  + V +++  +Y  ++CGLCGN++    +
Sbjct: 4563 PFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPAD 4622

Query: 903  DFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSS--VF 960
            D           ++       E  + P     P PC+            C ++ ++    
Sbjct: 4623 DLKAVGGKPAGWQVGGAQGCGECVSKP----CPSPCTPEQQESFGGPDACGVISATDGPL 4678

Query: 961  SICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCP 1019
            + CH  V P  +++ C+ D+C     G     C AVA+Y   C   GA +  WR PD CP
Sbjct: 4679 APCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCP 4736

Query: 1020 IFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDL 1079
            + C    P H    HYE CG+    +C          S+S  EGC   C ++  + +   
Sbjct: 4737 LQC----PAHS---HYELCGDSCPVSCP---------SLSAPEGCESAC-REGCVCDAGF 4779

Query: 1080 ----KKCVTADKCGCYVEDTHYPPG-ASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQ 1134
                  CV   +CGC  +  +YP G    P  E  + C C     V C           Q
Sbjct: 4780 VLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC-----------Q 4828

Query: 1135 DGAFC 1139
            +GA C
Sbjct: 4829 EGAAC 4833



 Score =  138 bits (348), Expect = 6e-32
 Identities = 126/429 (29%), Positives = 188/429 (43%), Gaps = 37/429 (8%)

Query: 1916 CSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--P 1973
            C+ G +   V    GC    E    C   GDPHY TFDG  Y   G C+Y +VE  S   
Sbjct: 449  CAAGQRCQVVGGKAGCVA--ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDD 506

Query: 1974 SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPY 2033
            ++  F V   N H   + +VS    + VR  +  V +    +  + V  Q +R  V+L  
Sbjct: 507  TLPAFSVEAKNEH-RGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSE 565

Query: 2034 KKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNTKGQCGTCTNTTSDD 2092
             +  L VYQSG   VV++   G++V+Y+     ++ LP  RF +   G CG      +DD
Sbjct: 566  GR--LRVYQSGPRAVVEL-VFGLVVTYDWDCQLALSLP-ARFQDQVCGLCGNYNGDPADD 621

Query: 2093 CILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL 2152
             + P G +  +    A  W ++D    +          PA T PG  +   H +     L
Sbjct: 622  FLTPDGALAPDAVEFASSWKLDDGD--YLCEDGCQNNCPACT-PGQAQ---HYE--GDRL 673

Query: 2153 CQLIK--DSLFAQCHALVPPQHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQNICL- 2208
            C ++   D  FA CH  + P+ + + CV+D C + G  L  C  L AYA  C +  I + 
Sbjct: 674  CGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVG 733

Query: 2209 DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN--NTVLVEGCFCPEGTMNYAP 2266
            DWR+  +  C + CP++  Y+ CGPA   +C  +++  N      VEGC C  G +  + 
Sbjct: 734  DWRSPAN--CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFV-ASG 790

Query: 2267 GFDVCVKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPK-------RCS-Q 2316
            G  V   +CGC   G    P +     E   + C C      + C+ K       RCS Q
Sbjct: 791  GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850

Query: 2317 KPVTHCVED 2325
              +  C  D
Sbjct: 851  NGLLGCYPD 859



 Score =  135 bits (339), Expect = 7e-31
 Identities = 127/510 (24%), Positives = 194/510 (38%), Gaps = 114/510 (22%)

Query: 413  LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSS---CHDKLD 469
            L +++    +G++ GLCGNFNG   DDF   +G   ++   F   W+A  S   C +   
Sbjct: 4970 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 5029

Query: 470  WLDDPCSLNIESANY-AEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDC 528
                P  L  E+A Y +   C  L+  + PF  C + + P+EY+++C YD C  + ++  
Sbjct: 5030 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAF 5089

Query: 529  LCAALSSYARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADS 587
            LC +L++Y  AC A GV +  WR +  C      CP    +     TCQ +C +LS    
Sbjct: 5090 LCRSLAAYTAACQAAGVAVKPWRTDSFCPL---HCPAHSHYSICTRTCQGSCAALSGLTG 5146

Query: 588  HCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE--ERCVCRD 645
                 F   +GC C D  FL  +G C+P+  C C H G YL     ++  +  ERC C  
Sbjct: 5147 CTTRCF---EGCECDDR-FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSC-- 5200

Query: 646  GRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPD 705
                                            S    L+CQ  AAG     C  G VC  
Sbjct: 5201 --------------------------------SSSSGLTCQ--AAG-----CPPGRVC-- 5219

Query: 706  GLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYG 765
                                         ++K +   C   RG  +C  +V     +  G
Sbjct: 5220 -----------------------------EVKAEARNCWATRG--LCVLSVGANLTTFDG 5248

Query: 766  SGHYITFDGKYYDFDGHC----------SYVAVQDYC-GQNSSLGSFSIITENVPCGTTG 814
            +    T  G  Y+    C            VA    C G+  ++G   I  ++   G   
Sbjct: 5249 ARGATTSPG-VYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQD---GMVT 5304

Query: 815  VTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKR 874
            +T +K + +   R +L  E    V + R                L+V    G+ V     
Sbjct: 5305 LTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGS-----------LLVRQKAGVQVWLGAN 5353

Query: 875  TTVFIKLAPSYKGTVCGLCGNFDHRSNNDF 904
              V + ++  + G +CG CGNFD    ND+
Sbjct: 5354 GKVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383



 Score =  132 bits (331), Expect = 6e-30
 Identities = 128/486 (26%), Positives = 182/486 (37%), Gaps = 66/486 (13%)

Query: 1894 TCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDP-----------------DGCCW-HW 1935
            TC     V   +  C+P  +   S G+     +DP                  G C  ++
Sbjct: 4012 TCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNY 4071

Query: 1936 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 1995
            E  C+   WGDPHY +FDG  + +QG C YVL     P V   G+         N     
Sbjct: 4072 EATCWL--WGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTV-TTKNQNRGN 4128

Query: 1996 PRTLIVRHETQEVLIKTVHMMPMQV-QVQVNRQAVALPYK-KYGLEVYQSGINYVVDIPE 2053
            P    VR  T   L   + +   ++ +V+VN    ALP     G      G +  + + +
Sbjct: 4129 PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVAD 4188

Query: 2054 LGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQ 2110
             G+ VSY+      V LP  YH       G CG      ++D + P+G +  +       
Sbjct: 4189 FGLQVSYDWNWRVDVTLPSSYH---GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 4245

Query: 2111 W-------LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQ 2163
            W       L  D  +  CP   +  +       G G   P    T  P         F  
Sbjct: 4246 WRAPGWDPLCWDECRGSCP---TCPEDRLEQYEGPGFCGPLSSGTGGP---------FTT 4293

Query: 2164 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALCAQQNICL-DWRNHTHGACLVE 2221
            CHA VPP+ ++  CV D C   G   + C +L +Y A C    + + DWR      C + 
Sbjct: 4294 CHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV--GCEIT 4351

Query: 2222 CPSHREYQACGPAEEPTCKSSSSQQNNTV----LVEGCFCPEGTMNYAPGFDVCV---KT 2274
            CP +  Y+ CGP    +C S +      V     VEGC C  G   +    D CV     
Sbjct: 4352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG---FVLSADRCVPLNNG 4408

Query: 2275 CGCVGPDNVPREFGEHFEFD--CKN-CVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLAT 2331
            CGC   +    E G  F  D  C   C C  GG  ++C P  C    V   +  G +   
Sbjct: 4409 CGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQ 4467

Query: 2332 EVNPAD 2337
             V+ A+
Sbjct: 4468 PVSTAE 4473



 Score =  130 bits (327), Expect = 2e-29
 Identities = 123/451 (27%), Positives = 172/451 (38%), Gaps = 56/451 (12%)

Query: 1912 PMPTCSN-GLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 1970
            P  TC   G Q V + + +  CW W         GDPHY +FDG  + +QG C YVL   
Sbjct: 2853 PQETCKEQGGQGVCLPNYEATCWLW---------GDPHYHSFDGRKFDFQGTCNYVLATT 2903

Query: 1971 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQV-QVQVNRQAV 2029
              P V   G+         N     P    VR  T   L   + +   ++ +V+VN    
Sbjct: 2904 GCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 2962

Query: 2030 ALPYK-KYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCGTC 2085
            ALP     G      G +  + + + G+ VSY+      V LP  YH       G CG  
Sbjct: 2963 ALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH---GAVCGLCGNM 3019

Query: 2086 TNTTSDDCILPSGEIVSNCEAAADQW-------LVNDPSKPHCPHSSSTTKRPAVTVPGG 2138
                ++D + P+G +  +       W       L  D  +  CP   +  +       G 
Sbjct: 3020 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP---TCPEDRLEQYEGP 3076

Query: 2139 GKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQAY 2197
            G   P    T  P         F  CHA VPP+ ++  CV D C   G   + C +L +Y
Sbjct: 3077 GFCGPLAPGTGGP---------FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASY 3127

Query: 2198 AALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV----LV 2252
             A C    + + DWR      C + CP +  Y+ CGP    +C S +      V     V
Sbjct: 3128 VAACQAAGVVIEDWRAQV--GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCV 3185

Query: 2253 EGCFCPEGTMNYAPGFDVCV---KTCGCVGPDNVPREFGEHFEFD--CKN-CVCLEGGSG 2306
            EGC C  G   +    D CV     CGC   +    E G  F  D  C   C C  GG  
Sbjct: 3186 EGCQCDAG---FVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGS 3241

Query: 2307 IICQPKRCSQKPVTHCVEDGTYLATEVNPAD 2337
            ++C P  C    V   +  G +    V+ A+
Sbjct: 3242 LVCTPASCGLGEVCGLLPSGQHGCQPVSTAE 3272



 Score =  128 bits (322), Expect = 7e-29
 Identities = 127/447 (28%), Positives = 178/447 (39%), Gaps = 51/447 (11%)

Query: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--PSVDNFGVYIDNYHCDPNDKVSCPRT 1998
            C   GDPHY TFDG  + + G C YVL +     P +  F V  +N     N +VS  R 
Sbjct: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRV 1310

Query: 1999 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGV 2056
            +     T +V   T+ +   Q +V VN   + LP       +   Q G + V++  + G+
Sbjct: 1311 I-----TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGL 1364

Query: 2057 LVSYNGLSFSVRLPYHRFGNNTKGQCGTCTN---TTSDDCILPSGEIVSNCEAAADQWLV 2113
             V+Y+ L + VR+     GN  +  CG C N      DD   P+G    N     + W  
Sbjct: 1365 RVAYD-LVYYVRVTVP--GNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEE 1421

Query: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--------SPLCQLIKDSL--FAQ 2163
              P  P  P        P    PG     P   C P           C L+       + 
Sbjct: 1422 VVPDSPCLP--------PTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 1473

Query: 2164 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALC-AQQNICLDWRNHTHGACLVE 2221
            CH LV PQ     C+FD C   G+ S+ C+++ AY + C A       WR  T   C +E
Sbjct: 1474 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETF--CPME 1531

Query: 2222 CPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 2280
            CP +  Y+ C       C + S+  Q      EGC C  G + Y     V ++ CGC   
Sbjct: 1532 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFL-YNGQACVPIQQCGCY-H 1589

Query: 2281 DNVPREFGEHFEFD-CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 2339
            + V  E  +    D C+       G G++CQ   C  KP   C   G  L+      D C
Sbjct: 1590 NGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSC--KPGQVCQPSGGILSCVTK--DPC 1645

Query: 2340 CNITVCKCNTSLCKEK--PSVCPLGFE 2364
              +T     T  CKE+    VC   +E
Sbjct: 1646 HGVTCRPQET--CKEQGGQGVCLPNYE 1670



 Score =  127 bits (319), Expect = 1e-28
 Identities = 122/451 (27%), Positives = 171/451 (37%), Gaps = 56/451 (12%)

Query: 1912 PMPTCSN-GLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 1970
            P  TC   G Q V + + +  CW W         GDPHY +FDG  + +QG C YVL   
Sbjct: 1652 PQETCKEQGGQGVCLPNYEATCWLW---------GDPHYHSFDGRKFDFQGTCNYVLATT 1702

Query: 1971 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQV-QVQVNRQAV 2029
              P V   G+         N     P    VR  T   L   + +   ++ +V+VN    
Sbjct: 1703 GCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 1761

Query: 2030 ALPYK-KYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCGTC 2085
            ALP     G      G +  + + + G+ VSY+      V LP  YH       G CG  
Sbjct: 1762 ALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH---GAVCGLCGNM 1818

Query: 2086 TNTTSDDCILPSGEIVSNCEAAADQW-------LVNDPSKPHCPHSSSTTKRPAVTVPGG 2138
                ++D + P+G +  +       W       L  D  +  CP   +  +       G 
Sbjct: 1819 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP---TCPEDRLEQYEGP 1875

Query: 2139 GKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQAY 2197
            G   P    T  P         F  CHA VPP+ ++  CV D C   G   + C +L +Y
Sbjct: 1876 GFCGPLAPGTGGP---------FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASY 1926

Query: 2198 AALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV----LV 2252
             A C    + + DWR      C + CP +  Y+ CG     +C S +      V     V
Sbjct: 1927 VAACQAAGVVIEDWRAQV--GCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCV 1984

Query: 2253 EGCFCPEGTMNYAPGFDVCV---KTCGCVGPDNVPREFGEHFEFD--CKN-CVCLEGGSG 2306
            EGC C  G   +    D CV     CGC   +    E G  F  D  C   C C  GG  
Sbjct: 1985 EGCQCDAG---FVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGS 2040

Query: 2307 IICQPKRCSQKPVTHCVEDGTYLATEVNPAD 2337
            ++C P  C    V   +  G +    V+ A+
Sbjct: 2041 LVCTPASCGLGEVCGLLPSGQHGCQPVSTAE 2071



 Score =  127 bits (318), Expect = 2e-28
 Identities = 126/446 (28%), Positives = 178/446 (39%), Gaps = 49/446 (10%)

Query: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--PSVDNFGVYIDNYHCDPNDKVSCPRT 1998
            C   GDPHY TFDG  + + G C YVL +     P +  F V  +N     N +VS  R 
Sbjct: 2453 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRV 2511

Query: 1999 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGV 2056
            +     T +V   T+ +   Q +V VN   + LP       +   Q G + V++  + G+
Sbjct: 2512 I-----TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGL 2565

Query: 2057 LVSYNGLSFSVRLPYHRFGNNTKGQCGTCTN---TTSDDCILPSGEIVSNCEAAADQWLV 2113
             V+Y+ L + VR+     GN  +  CG C N      DD   P+G    N     + W  
Sbjct: 2566 RVAYD-LVYYVRVTVP--GNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEE 2622

Query: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--------SPLCQLIKDSL--FAQ 2163
              P  P  P        P    PG     P ++C P           C L+       + 
Sbjct: 2623 VVPDSPCLP--------PPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSS 2674

Query: 2164 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALC-AQQNICLDWRNHTHGACLVE 2221
            CH LV PQ     C+FD C   G+ S+ C+++ AY + C A       WRN T   C +E
Sbjct: 2675 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETF--CPME 2732

Query: 2222 CPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 2280
            CP +  Y+ C       C + S+  Q      EGC C  G + Y     V ++ CGC   
Sbjct: 2733 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFL-YNGQACVPIQQCGCYHN 2791

Query: 2281 DNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCC 2340
                         +C+       G  ++CQ   C  KP   C   G  L+  VN  D C 
Sbjct: 2792 GAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC--KPGQVCQPSGGILSC-VN-KDPCH 2847

Query: 2341 NITVCKCNTSLCKEK--PSVCPLGFE 2364
             +T     T  CKE+    VC   +E
Sbjct: 2848 GVTCRPQET--CKEQGGQGVCLPNYE 2871



 Score =  126 bits (317), Expect = 2e-28
 Identities = 92/266 (34%), Positives = 123/266 (46%), Gaps = 31/266 (11%)

Query: 412 QLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWL 471
           QL ++L    Q QV GLCGN+NG   DDF T  G +      FA++WK      D  D+L
Sbjct: 594 QLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKL-----DDGDYL 648

Query: 472 -DDPCSLNIESAN--YAEHW-----CSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQ 523
            +D C  N  +     A+H+     C +L K + PF  CH  +DP  + ++C YD C   
Sbjct: 649 CEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVG 708

Query: 524 NNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTCRSL 582
                LC  LS+YA+AC   G+ +  WR    C     SCP +  +      C  +C   
Sbjct: 709 GERLSLCRGLSAYAQACLELGISVGDWRSPANCPL---SCPANSRYELCGPACPTSCNG- 764

Query: 583 SEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE---E 639
           + A S+C  G   V+GC C    F+   G CVP + C C  +GL L  G  V   E    
Sbjct: 765 AAAPSNC-SGRPCVEGCVCLP-GFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQR 822

Query: 640 RCVCRDGRLH---CRQIRLIGQSCTA 662
           RC C +G  H   CR      QSC A
Sbjct: 823 RCTC-NGATHQVTCRD----KQSCPA 843



 Score =  125 bits (315), Expect = 4e-28
 Identities = 127/447 (28%), Positives = 178/447 (39%), Gaps = 51/447 (11%)

Query: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--PSVDNFGVYIDNYHCDPNDKVSCPRT 1998
            C   GDPHY TFDG  + + G C YVL +     P +  F V  +N     N +VS  R 
Sbjct: 3654 CQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRV 3712

Query: 1999 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGV 2056
            +     T +V   T+ +   Q +V VN   + LP       +   Q G + V++  + G+
Sbjct: 3713 I-----TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGL 3766

Query: 2057 LVSYNGLSFSVRLPYHRFGNNTKGQCGTCTN---TTSDDCILPSGEIVSNCEAAADQWLV 2113
             V+Y+ L + VR+     GN  +  CG C N      DD   P+G    N     + W  
Sbjct: 3767 RVAYD-LVYYVRVTVP--GNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEE 3823

Query: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--------SPLCQLIKDSL--FAQ 2163
              P  P  P        P    PG     P   C P           C L+       + 
Sbjct: 3824 VVPDSPCLP--------PPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSS 3875

Query: 2164 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALC-AQQNICLDWRNHTHGACLVE 2221
            CH LV PQ     C+FD C   G+ S+ C+++ AY + C A       WRN T   C +E
Sbjct: 3876 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETF--CPME 3933

Query: 2222 CPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 2280
            CP +  Y+ C       C + S+  Q      EGC C  G + Y     V ++ CGC   
Sbjct: 3934 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFL-YNGQACVPIQQCGCY-H 3991

Query: 2281 DNVPREFGEHFEFD-CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 2339
            + V  E  +    D C+       G  ++CQ   C  KP   C   G  L+      D C
Sbjct: 3992 NGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC--KPGQVCQPSGGILSCVTK--DPC 4047

Query: 2340 CNITVCKCNTSLCKEK--PSVCPLGFE 2364
              +T     T  CKE+    VC   +E
Sbjct: 4048 HGVTCRPQET--CKEQGGQGVCLPNYE 4072



 Score =  125 bits (314), Expect = 6e-28
 Identities = 113/425 (26%), Positives = 166/425 (39%), Gaps = 42/425 (9%)

Query: 1905 KVECEPPPMPTCSNGL-----QPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSY 1959
            + EC P    TC  G      +  R+ED    C    C   C   G  HY+T DG  Y  
Sbjct: 4816 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDL 4874

Query: 1960 QGNCTYVLVE--EISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMP 2017
             G+C+YVL +     P  ++F + ++      N      R L+        +   V  + 
Sbjct: 4875 HGSCSYVLAQVCHPKPGDEDFSIVLEK-----NAAGDLQRLLV-------TVAGQVVSLA 4922

Query: 2018 MQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNG---LSFSVRLPYHRF 2074
               QV V+ +AVALP     + V   G N V+   + G+ + ++G   L  S+  P   F
Sbjct: 4923 QGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTK-GLRLLFDGDAHLLMSIPSP---F 4978

Query: 2075 GNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVT 2134
                 G CG      SDD +LP+G   S+ E     W     SK  C         P   
Sbjct: 4979 RGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCGEGCGPQGCPVCL 5037

Query: 2135 VPGGGKTTPHKDCTPSPLCQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPG-SSLEC 2191
                 +T P++    +  C  +++    FA C A++ P  Y+  CV+D C   G  +  C
Sbjct: 5038 AE---ETAPYES---NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 5091

Query: 2192 ASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NT 2249
             SL AY A C    + +  WR  T   C + CP+H  Y  C    + +C + S      T
Sbjct: 5092 RSLAAYTAACQAAGVAVKPWR--TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT 5149

Query: 2250 VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIIC 2309
               EGC C +  +  + G  + V+ CGC                DC         SG+ C
Sbjct: 5150 RCFEGCECDDRFL-LSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTC 5208

Query: 2310 QPKRC 2314
            Q   C
Sbjct: 5209 QAAGC 5213



 Score =  124 bits (311), Expect = 1e-27
 Identities = 122/442 (27%), Positives = 183/442 (41%), Gaps = 60/442 (13%)

Query: 1913 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 1972
            +P+  +G QPV   +             C  WGDPHYVT DG  +++QG C Y+L     
Sbjct: 2057 LPSGQHGCQPVSTAE-------------CQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCH 2103

Query: 1973 P---SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAV 2029
                  +NF V + N H   +  VS  R++ ++     + +          ++QV+   V
Sbjct: 2104 GPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQIYNHSLTLSA----RWPRKLQVDGVFV 2158

Query: 2030 ALPYKKYG-LEVYQSGINYVVDIPELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTN 2087
             LP++    L  + SG + VV     G+ ++++G SF  +R+P    G+     CG C N
Sbjct: 2159 TLPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLRVPAAYAGS----LCGLCGN 2213

Query: 2088 TTSD--DCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHK 2145
               D  D +   G   +  +    Q      SKP CP   +  ++ +    GG       
Sbjct: 2214 YNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKP-CPSPCTPEQQESF---GGPDACGVI 2269

Query: 2146 DCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQ 2204
              T  PL         A CH LVPP  Y+  C+ D+C + G     C ++  Y A C   
Sbjct: 2270 SATDGPL---------APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAA 2320

Query: 2205 NICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTM 2262
               L +WR      C  +CP+H  Y+ CG +   +C S S+ +   +   EGC C  G  
Sbjct: 2321 GAQLREWRRPDF--CPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAG-- 2376

Query: 2263 NYAPGFDVCVKT--CGCVGPDNVPREFGEHF--EFDCKN-CVCLEGGSGIICQPKRCSQK 2317
             +    D CV    CGC+  D      G+ F     C + C C EGG  + C+P  C   
Sbjct: 2377 -FVLSGDTCVPVGQCGCLHDDRY-YPLGQTFYPGPGCDSLCRCREGGE-VSCEPSSCG-- 2431

Query: 2318 PVTHCVEDGTYLATEVNPADTC 2339
            P   C   G  L      + TC
Sbjct: 2432 PHETCRPSGGSLGCVAVGSTTC 2453



 Score =  124 bits (310), Expect = 2e-27
 Identities = 122/442 (27%), Positives = 182/442 (41%), Gaps = 60/442 (13%)

Query: 1913 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 1972
            +P+  +G QPV   +             C  WGDPHYVT DG  + +QG C Y+L     
Sbjct: 3258 LPSGQHGCQPVSTAE-------------CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCH 3304

Query: 1973 P---SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAV 2029
                  +NF V + N H   +  VS  R++ ++     + +          ++QV+   V
Sbjct: 3305 GPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQIYNHSLTLSA----RWPRKLQVDGVFV 3359

Query: 2030 ALPYKKYG-LEVYQSGINYVVDIPELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTN 2087
             LP++    L  + SG + VV     G+ ++++G SF  +R+P    G+     CG C N
Sbjct: 3360 TLPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLRVPAAYAGS----LCGLCGN 3414

Query: 2088 TTSD--DCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHK 2145
               D  D +   G   +  +    Q      SKP CP   +  ++ +    GG       
Sbjct: 3415 YNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKP-CPSPCTPEQQESF---GGPDACGVI 3470

Query: 2146 DCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQ 2204
              T  PL         A CH LVPP  Y+  C+ D+C + G     C ++  Y A C   
Sbjct: 3471 SATDGPL---------APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAA 3521

Query: 2205 NICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTM 2262
               L +WR      C  +CP+H  Y+ CG +   +C S S+ +   +   EGC C  G  
Sbjct: 3522 GAQLREWRRPDF--CPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAG-- 3577

Query: 2263 NYAPGFDVCVKT--CGCVGPDNVPREFGEHF--EFDCKN-CVCLEGGSGIICQPKRCSQK 2317
             +    D CV    CGC+  D      G+ F     C + C C EGG  + C+P  C   
Sbjct: 3578 -FVLSGDTCVPVGQCGCLHDDRY-YPLGQTFYPGPGCDSLCRCREGGE-VSCEPSSCG-- 3632

Query: 2318 PVTHCVEDGTYLATEVNPADTC 2339
            P   C   G  L      + TC
Sbjct: 3633 PHETCRPSGGSLGCVAVGSTTC 3654



 Score =  119 bits (297), Expect = 5e-26
 Identities = 121/456 (26%), Positives = 178/456 (39%), Gaps = 59/456 (12%)

Query: 1915 TCSNGLQPVRVEDPDGCCWHWECD-------CY------CTGWGDPHYVTFDGLYYSYQG 1961
            TC+     V   D   C     C        CY      C G GDPHYV+FDG  + + G
Sbjct: 825  TCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMG 884

Query: 1962 NCTYVLVEEI--SPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQ 2019
             CTY+LV     + ++  F V ++N H       +   T  VR E + V +      P Q
Sbjct: 885  TCTYLLVGSCGQNAALPAFRVLVENEH---RGSQTVSYTRAVRVEARGVKVAVRREYPGQ 941

Query: 2020 VQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNT 2078
            V V    Q +        ++V++ G + VV   + G+ V+Y+     + ++P   +    
Sbjct: 942  VLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVP-SSYAEAL 999

Query: 2079 KGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGG 2138
             G CG      +DD  L  G   +N  A  + W   + ++P C            T PG 
Sbjct: 1000 CGLCGNFNGDPADDLALRGGGQAANALAFGNSW--QEETRPGC----------GATEPG- 1046

Query: 2139 GKTTPHKDCTPSPL------CQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPGSSLE 2190
                P  D   +        C ++ D    F +CH+ + PQ     CV+D C +PG S  
Sbjct: 1047 --DCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGP 1104

Query: 2191 -CASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN- 2247
             C +L  YAA C      +  WR+     C + CP H  Y+AC      +C         
Sbjct: 1105 LCDALATYAAACQAAGATVHPWRSEE--LCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC 1162

Query: 2248 NTVLVEGCFCPEGTMNYAPGFDVC--VKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEG 2303
             +   EGC C EG   +A   + C  + +CGCV  G  + P +           C C EG
Sbjct: 1163 GSECHEGCVCDEG---FALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEG 1219

Query: 2304 GSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 2339
            G  + C+   C   P   C   G  L      + TC
Sbjct: 1220 GL-VSCESSSCG--PHEACQPSGGSLGCVAVGSSTC 1252



 Score =  117 bits (294), Expect = 1e-25
 Identities = 119/428 (27%), Positives = 183/428 (42%), Gaps = 56/428 (13%)

Query: 1913 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 1972
            +P+  +G QPV   +             C  WGDPHYVT DG  + +QG C Y+L     
Sbjct: 4459 LPSGQHGCQPVSTAE-------------CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCH 4505

Query: 1973 P---SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAV 2029
                  +NF V + N H   +  VS  R++ ++     + +          ++QV+   V
Sbjct: 4506 GPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQIYNHSLTLSA----RWPRKLQVDGVFV 4560

Query: 2030 ALPYKKYG-LEVYQSGINYVVDIPELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTN 2087
            ALP++    L  + SG + VV     G+ ++++G SF  +R+P   +  +  G CG    
Sbjct: 4561 ALPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLRVP-AAYAASLCGLCGNYNQ 4618

Query: 2088 TTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDC 2147
              +DD     G+  +  +    Q      SKP CP   +  ++ +    GG         
Sbjct: 4619 DPADDLKAVGGK-PAGWQVGGAQGCGECVSKP-CPSPCTPEQQESF---GGPDACGVISA 4673

Query: 2148 TPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNI 2206
            T  PL         A CH LVPP  Y+  C+ D+C + G     C ++  Y A C     
Sbjct: 4674 TDGPL---------APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGA 4724

Query: 2207 CL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTMNY 2264
             L +WR      C ++CP+H  Y+ CG +   +C S S+ +   +   EGC C  G   +
Sbjct: 4725 QLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG---F 4779

Query: 2265 APGFDVCVKT--CGCVGPDNVPREFGEHF--EFDC-KNCVCLEGGSGIICQPKRCSQKPV 2319
                D CV    CGC+  D      GE F    +C + C C  GG  + CQ +  +  P 
Sbjct: 4780 VLSGDTCVPVGQCGCL-HDGRYYPLGEVFYPGPECERRCECGPGGH-VTCQ-EGAACGPH 4836

Query: 2320 THC-VEDG 2326
              C +EDG
Sbjct: 4837 EECRLEDG 4844



 Score =  107 bits (266), Expect = 2e-22
 Identities = 89/352 (25%), Positives = 139/352 (39%), Gaps = 34/352 (9%)

Query: 12  CLALSLAGGSELQTEGRTRN---HGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCR 68
           C  +  A G   Q  G           VC   G+ HY TFDG  +   G C Y     C 
Sbjct: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 503

Query: 69  --GSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGL 126
              +   F+V  K     +   + V  + +     ++ LTR         V   +    L
Sbjct: 504 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEV----GFVLVDNQRSRL 559

Query: 127 LIEKSDAYTKVYSRA---------GLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQS 177
            +  S+   +VY            GL + ++ +  L L L  +F++  CGLCG+YNG  +
Sbjct: 560 PVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA 619

Query: 178 YSEFLSDGVLF-SPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAE-------CERLL 229
                 DG L    +EF +  K++  D +CED  +   PA C+  +A+       C  L 
Sbjct: 620 DDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLT 678

Query: 230 TAEA-FADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTA 288
             +  FA C D +   P+L  C  D C   G    +C  ++ +++ C   G   G+WR+ 
Sbjct: 679 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 738

Query: 289 TSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHR-MDGCFCPEG 339
            +        +CP N  Y   G  C  +C+     S C     ++GC C  G
Sbjct: 739 AN-----CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG 785



 Score =  104 bits (259), Expect = 1e-21
 Identities = 84/319 (26%), Positives = 129/319 (40%), Gaps = 30/319 (9%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAGVES 93
            C  WG+ HY T DG  F F G C+Y  ++ C G     + F V +      ++A +   S
Sbjct: 4474 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 4533

Query: 94   ILLTIKDDTIYLT----RHLAVLNGAVVSTPHYSPGLL-IEKSDAYTKVYSRAGLTLMWN 148
            + L I + ++ L+    R L V +G  V+ P     LL    S A   V + +GL+L ++
Sbjct: 4534 VTLQIYNHSLTLSARWPRKLQV-DGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 4592

Query: 149  REDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED 208
             +  + L +   +    CGLCG+YN      +  + G   +  + G  Q        C +
Sbjct: 4593 GDSFVRLRVPAAYAASLCGLCGNYNQ-DPADDLKAVGGKPAGWQVGGAQG-------CGE 4644

Query: 209  PEEEVAPASCSEHRAE-------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGG 260
               +  P+ C+  + E       C  +   +   A C  LVP   Y + C  D C+  G 
Sbjct: 4645 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 4704

Query: 261  DTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHL 320
               +C  VA +   C  AG + G WR             CP +  Y   G  C  +C  L
Sbjct: 4705 PGGLCPAVATYVAACQAAGAQLGEWRRPDF-----CPLQCPAHSHYELCGDSCPVSCPSL 4759

Query: 321  EVSSLCEEHRMDGCFCPEG 339
                 CE    +GC C  G
Sbjct: 4760 SAPEGCESACREGCVCDAG 4778



 Score =  103 bits (256), Expect = 3e-21
 Identities = 83/319 (26%), Positives = 128/319 (40%), Gaps = 30/319 (9%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAGVES 93
            C  WG+ HY T DG  F F G C+Y  ++ C G     + F V +      ++A +   S
Sbjct: 2072 CQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 2131

Query: 94   ILLTIKDDTIYLT----RHLAVLNGAVVSTPHYSPGLL-IEKSDAYTKVYSRAGLTLMWN 148
            + L I + ++ L+    R L V +G  V+ P     LL    S A   V + +GL+L ++
Sbjct: 2132 VTLQIYNHSLTLSARWPRKLQV-DGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 2190

Query: 149  REDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED 208
             +  + L +   +    CGLCG+YN      +  + G   +  + G  Q        C +
Sbjct: 2191 GDSFVRLRVPAAYAGSLCGLCGNYN-QDPADDLKAVGGKPAGWQVGGAQG-------CGE 2242

Query: 209  PEEEVAPASCSEHRAE-------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGG 260
               +  P+ C+  + E       C  +   +   A C  LVP   Y + C  D C+  G 
Sbjct: 2243 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2302

Query: 261  DTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHL 320
               +C  VA +   C  AG +   WR             CP +  Y   G  C  +C  L
Sbjct: 2303 PGGLCPAVATYVAACQAAGAQLREWRRPDF-----CPFQCPAHSHYELCGDSCPGSCPSL 2357

Query: 321  EVSSLCEEHRMDGCFCPEG 339
                 CE    +GC C  G
Sbjct: 2358 SAPEGCESACREGCVCDAG 2376



 Score =  102 bits (255), Expect = 4e-21
 Identities = 109/392 (27%), Positives = 157/392 (40%), Gaps = 39/392 (9%)

Query: 348  VVLLADKKKNVVVFKSD-GSVLLNELQVNLPHVTAS--FSVFRPSSYHIMVSMAIGVRLQ 404
            VV +A    N+ + K + G V +N +   LP   A    SV + +S  ++V+      LQ
Sbjct: 4136 VVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA---DFGLQ 4192

Query: 405  VQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS-- 462
            V      ++ VTL  +  G V GLCGN +    +D    +G +  +   +  +W+A    
Sbjct: 4193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 4252

Query: 463  -SCHDKLDWLDDPCSLNIESANYAEHWCSLLKK-TETPFGRCHSAVDPAEYYKRCKYDTC 520
              C D+       C  +         +C  L   T  PF  CH+ V P  ++K C  D C
Sbjct: 4253 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVC 4312

Query: 521  NCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTC 579
                + D LC AL+SY  AC A GV++  WR  V C     +CP +  +      C  +C
Sbjct: 4313 MGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI---TCPENSHYEVCGPPCPASC 4369

Query: 580  RSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK-CSCYHRGLYLEAG-----DV 633
             S +   +  +     V+GC C D  F+    RCVPL   C C+  G Y EAG     D 
Sbjct: 4370 PSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADG 4428

Query: 634  VVRQEERCVCRDGRLHCRQIRL-IGQSC-TAPKIHMDCSNLTALATSKPRALSCQTLAAG 691
               Q  RC    G L C      +G+ C   P     C  ++           CQ     
Sbjct: 4429 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS--------TAECQAWGDP 4480

Query: 692  YYHTECVSGCVCPDGLMDDGRGGCVVEKECPC 723
            +Y        V  DG   D +G C      PC
Sbjct: 4481 HY--------VTLDGHRFDFQGTCEYLLSAPC 4504



 Score =  102 bits (254), Expect = 5e-21
 Identities = 75/235 (31%), Positives = 97/235 (41%), Gaps = 27/235 (11%)

Query: 427  GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS--SCH----DKLDWLDDPCSLNIE 480
            GLCGNFNG   DD     G   A    F N+W+ ++   C          LD   +  ++
Sbjct: 1001 GLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQ 1060

Query: 481  SANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARAC 540
            S N     C +L   + PF  CHS +DP    + C YD C        LC AL++YA AC
Sbjct: 1061 SKNE----CGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAAC 1116

Query: 541  TAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSL---SEADSHCLEGFAPV 596
             A G  +  WR E +C     SCP    +      C  +C  L       S C E     
Sbjct: 1117 QAAGATVHPWRSEELCPL---SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHE----- 1168

Query: 597  DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQ---EERCVCRDGRL 648
             GC C D  F      C+PLA C C H+G Y   G         +  C C++G L
Sbjct: 1169 -GCVC-DEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGL 1221



 Score =  102 bits (254), Expect = 5e-21
 Identities = 109/392 (27%), Positives = 157/392 (40%), Gaps = 39/392 (9%)

Query: 348  VVLLADKKKNVVVFKSD-GSVLLNELQVNLPHVTAS--FSVFRPSSYHIMVSMAIGVRLQ 404
            VV +A    N+ + K + G V +N +   LP   A    SV + +S  ++V+      LQ
Sbjct: 2935 VVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA---DFGLQ 2991

Query: 405  VQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS-- 462
            V      ++ VTL  +  G V GLCGN +    +D    +G +  +   +  +W+A    
Sbjct: 2992 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 3051

Query: 463  -SCHDKLDWLDDPCSLNIESANYAEHWCS-LLKKTETPFGRCHSAVDPAEYYKRCKYDTC 520
              C D+       C  +         +C  L   T  PF  CH+ V P  ++K C  D C
Sbjct: 3052 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVC 3111

Query: 521  NCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTC 579
                + D LC AL+SY  AC A GV++  WR  V C     +CP +  +      C  +C
Sbjct: 3112 MGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI---TCPENSHYEVCGPPCPASC 3168

Query: 580  RSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK-CSCYHRGLYLEAG-----DV 633
             S +   +  +     V+GC C D  F+    RCVPL   C C+  G Y EAG     D 
Sbjct: 3169 PSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADG 3227

Query: 634  VVRQEERCVCRDGRLHCRQIRL-IGQSC-TAPKIHMDCSNLTALATSKPRALSCQTLAAG 691
               Q  RC    G L C      +G+ C   P     C  ++           CQ     
Sbjct: 3228 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS--------TAECQAWGDP 3279

Query: 692  YYHTECVSGCVCPDGLMDDGRGGCVVEKECPC 723
            +Y        V  DG   D +G C      PC
Sbjct: 3280 HY--------VTLDGHRFDFQGTCEYLLSAPC 3303



 Score =  102 bits (254), Expect = 5e-21
 Identities = 83/319 (26%), Positives = 128/319 (40%), Gaps = 30/319 (9%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAGVES 93
            C  WG+ HY T DG  F F G C+Y  ++ C G     + F V +      ++A +   S
Sbjct: 3273 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 3332

Query: 94   ILLTIKDDTIYLT----RHLAVLNGAVVSTPHYSPGLL-IEKSDAYTKVYSRAGLTLMWN 148
            + L I + ++ L+    R L V +G  V+ P     LL    S A   V + +GL+L ++
Sbjct: 3333 VTLQIYNHSLTLSARWPRKLQV-DGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 3391

Query: 149  REDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED 208
             +  + L +   +    CGLCG+YN      +  + G   +  + G  Q        C +
Sbjct: 3392 GDSFVRLRVPAAYAGSLCGLCGNYN-QDPADDLKAVGGKPAGWQVGGAQG-------CGE 3443

Query: 209  PEEEVAPASCSEHRAE-------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGG 260
               +  P+ C+  + E       C  +   +   A C  LVP   Y + C  D C+  G 
Sbjct: 3444 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 3503

Query: 261  DTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHL 320
               +C  VA +   C  AG +   WR             CP +  Y   G  C  +C  L
Sbjct: 3504 PGGLCPAVATYVAACQAAGAQLREWRRPDF-----CPFQCPAHSHYELCGDSCPGSCPSL 3558

Query: 321  EVSSLCEEHRMDGCFCPEG 339
                 CE    +GC C  G
Sbjct: 3559 SAPEGCESACREGCVCDAG 3577



 Score =  102 bits (253), Expect = 7e-21
 Identities = 94/317 (29%), Positives = 137/317 (43%), Gaps = 21/317 (6%)

Query: 348  VVLLADKKKNVVVFKSD-GSVLLNELQVNLPHVTAS--FSVFRPSSYHIMVSMAIGVRLQ 404
            VV +A    N+ + K + G V +N +   LP   A    SV + +S  ++V+      LQ
Sbjct: 1734 VVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA---DFGLQ 1790

Query: 405  VQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS-- 462
            V      ++ VTL  +  G V GLCGN +    +D    +G +  +   +  +W+A    
Sbjct: 1791 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1850

Query: 463  -SCHDKLDWLDDPCSLNIESANYAEHWCS-LLKKTETPFGRCHSAVDPAEYYKRCKYDTC 520
              C D+       C  +         +C  L   T  PF  CH+ V P  ++K C  D C
Sbjct: 1851 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVC 1910

Query: 521  NCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTC 579
                + D LC AL+SY  AC A GV++  WR  V C     +CP +  +    + C  +C
Sbjct: 1911 MGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI---TCPENSHYEVCGSPCPASC 1967

Query: 580  RSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK-CSCYHRGLYLEAG-----DV 633
             S +   +  +     V+GC C D  F+    RCVPL   C C+  G Y EAG     D 
Sbjct: 1968 PSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADG 2026

Query: 634  VVRQEERCVCRDGRLHC 650
               Q  RC    G L C
Sbjct: 2027 TCSQWCRCGPGGGSLVC 2043



 Score = 98.2 bits (243), Expect = 9e-20
 Identities = 80/280 (28%), Positives = 111/280 (39%), Gaps = 24/280 (8%)

Query: 374  VNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFN 433
            V LP    S      S   ++V+   G+ L       ++L V    A  G + GLCGN+N
Sbjct: 2158 VTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA--GSLCGLCGNYN 2215

Query: 434  GLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLK 493
                DD K   G       G A   +    C  K      PC+   + +      C ++ 
Sbjct: 2216 QDPADDLKAVGGKPAGWQVGGA---QGCGECVSKP--CPSPCTPEQQESFGGPDACGVIS 2270

Query: 494  KTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWRE- 552
             T+ P   CH  V PA+Y++ C  D C  Q +   LC A+++Y  AC A G  L  WR  
Sbjct: 2271 ATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRP 2330

Query: 553  HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFAPVDGCGCPDHTFLDE 609
              C      CP    +     +C  +C SLS     +S C E      GC C D  F+  
Sbjct: 2331 DFC---PFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACRE------GCVC-DAGFVLS 2380

Query: 610  KGRCVPLAKCSCYHRGLYLEAGDVVVRQ---EERCVCRDG 646
               CVP+ +C C H   Y   G         +  C CR+G
Sbjct: 2381 GDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG 2420



 Score = 98.2 bits (243), Expect = 9e-20
 Identities = 80/280 (28%), Positives = 111/280 (39%), Gaps = 24/280 (8%)

Query: 374  VNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFN 433
            V LP    S      S   ++V+   G+ L       ++L V    A  G + GLCGN+N
Sbjct: 3359 VTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA--GSLCGLCGNYN 3416

Query: 434  GLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLK 493
                DD K   G       G A   +    C  K      PC+   + +      C ++ 
Sbjct: 3417 QDPADDLKAVGGKPAGWQVGGA---QGCGECVSKP--CPSPCTPEQQESFGGPDACGVIS 3471

Query: 494  KTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWRE- 552
             T+ P   CH  V PA+Y++ C  D C  Q +   LC A+++Y  AC A G  L  WR  
Sbjct: 3472 ATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRP 3531

Query: 553  HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFAPVDGCGCPDHTFLDE 609
              C      CP    +     +C  +C SLS     +S C E      GC C D  F+  
Sbjct: 3532 DFC---PFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACRE------GCVC-DAGFVLS 3581

Query: 610  KGRCVPLAKCSCYHRGLYLEAGDVVVRQ---EERCVCRDG 646
               CVP+ +C C H   Y   G         +  C CR+G
Sbjct: 3582 GDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG 3621



 Score = 98.2 bits (243), Expect = 9e-20
 Identities = 80/317 (25%), Positives = 134/317 (42%), Gaps = 28/317 (8%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVESI 94
            C   G  HY T DG V+   G C Y  A  C  +   ++F++ L++      A   ++ +
Sbjct: 4856 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKN-----AAGDLQRL 4910

Query: 95   LLTIKDDTIYLTRHLAV-LNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDAL 153
            L+T+    + L +   V ++G  V+ P     + +        + +  GL L+++ +  L
Sbjct: 4911 LVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHL 4970

Query: 154  MLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVVCED---P 209
            ++ + + FR   CGLCG++NG  S    L +G   S +E FG   +       C +   P
Sbjct: 4971 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGP 5030

Query: 210  E-------EEVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGGD 261
            +       EE AP   +E    C +L   +  FA CQ ++    Y R C  D C   G  
Sbjct: 5031 QGCPVCLAEETAPYESNE---ACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 5087

Query: 262  TCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLE 321
              +C ++A ++  C  AG     WRT +          CP +  Y      C  +C+ L 
Sbjct: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSF-----CPLHCPAHSHYSICTRTCQGSCAALS 5142

Query: 322  VSSLCEEHRMDGCFCPE 338
              + C     +GC C +
Sbjct: 5143 GLTGCTTRCFEGCECDD 5159



 Score = 88.6 bits (218), Expect = 7e-17
 Identities = 85/328 (25%), Positives = 128/328 (39%), Gaps = 33/328 (10%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFA-SDCRG----SYKEFAVHLKRGPGQAEAPAGV 91
            C  WG+ HY +FDG  F F G C+Y  A + C G        F V  K       A + V
Sbjct: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732

Query: 92   ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
              +        ++I  D I   R   VL    VS       + + +  +   + +  GL 
Sbjct: 1733 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVA--DGRISVTQGASKALLVADFGLQ 1790

Query: 145  LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPD 203
            + ++    + + L + +    CGLCG+ +   +  +   +G L   +  +G   +    D
Sbjct: 1791 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1850

Query: 204  VVCEDPEEEVAPASCSEHRAE-------CERLL--TAEAFADCQDLVPLEPYLRACQQDR 254
             +C D      P +C E R E       C  L   T   F  C   VP E + + C  D 
Sbjct: 1851 PLCWDECRGSCP-TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 1909

Query: 255  CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCM 314
            C   G    +C  +A +   C  AG    +WR        G   TCP N  Y   GSPC 
Sbjct: 1910 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-----GCEITCPENSHYEVCGSPCP 1964

Query: 315  DTC---SHLEVSSLCEEHRMDGCFCPEG 339
             +C   + L   ++CE   ++GC C  G
Sbjct: 1965 ASCPSPAPLTTPAVCEGPCVEGCQCDAG 1992



 Score = 86.7 bits (213), Expect = 3e-16
 Identities = 84/328 (25%), Positives = 127/328 (38%), Gaps = 33/328 (10%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFA-SDCRG----SYKEFAVHLKRGPGQAEAPAGV 91
            C  WG+ HY +FDG  F F G C+Y  A + C G        F V  K       A + V
Sbjct: 2874 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 2933

Query: 92   ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
              +        ++I  D I   R   VL    VS       + + +  +   + +  GL 
Sbjct: 2934 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVA--DGRISVTQGASKALLVADFGLQ 2991

Query: 145  LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPD 203
            + ++    + + L + +    CGLCG+ +   +  +   +G L   +  +G   +    D
Sbjct: 2992 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 3051

Query: 204  VVCEDPEEEVAPASCSEHRAE-------CERLL--TAEAFADCQDLVPLEPYLRACQQDR 254
             +C D      P +C E R E       C  L   T   F  C   VP E + + C  D 
Sbjct: 3052 PLCWDECRGSCP-TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 3110

Query: 255  CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCM 314
            C   G    +C  +A +   C  AG    +WR        G   TCP N  Y   G PC 
Sbjct: 3111 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-----GCEITCPENSHYEVCGPPCP 3165

Query: 315  DTC---SHLEVSSLCEEHRMDGCFCPEG 339
             +C   + L   ++CE   ++GC C  G
Sbjct: 3166 ASCPSPAPLTTPAVCEGPCVEGCQCDAG 3193



 Score = 86.3 bits (212), Expect = 4e-16
 Identities = 84/328 (25%), Positives = 127/328 (38%), Gaps = 33/328 (10%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFA-SDCRG----SYKEFAVHLKRGPGQAEAPAGV 91
            C  WG+ HY +FDG  F F G C+Y  A + C G        F V  K       A + V
Sbjct: 4075 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 4134

Query: 92   ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
              +        ++I  D I   R   VL    VS       + + +  +   + +  GL 
Sbjct: 4135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVA--DGRISVAQGASKALLVADFGLQ 4192

Query: 145  LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPD 203
            + ++    + + L + +    CGLCG+ +   +  +   +G L   +  +G   +    D
Sbjct: 4193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 4252

Query: 204  VVCEDPEEEVAPASCSEHRAE-------CERLL--TAEAFADCQDLVPLEPYLRACQQDR 254
             +C D      P +C E R E       C  L   T   F  C   VP E + + C  D 
Sbjct: 4253 PLCWDECRGSCP-TCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV 4311

Query: 255  CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCM 314
            C   G    +C  +A +   C  AG    +WR        G   TCP N  Y   G PC 
Sbjct: 4312 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-----GCEITCPENSHYEVCGPPCP 4366

Query: 315  DTC---SHLEVSSLCEEHRMDGCFCPEG 339
             +C   + L   ++CE   ++GC C  G
Sbjct: 4367 ASCPSPAPLTTPAVCEGPCVEGCQCDAG 4394



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 88/337 (26%), Positives = 127/337 (37%), Gaps = 43/337 (12%)

Query: 33   GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAV---HLKRGPGQAEA 87
            G + C   G+ HY TFDG  F F G C Y  A  C  R     FAV   ++  G G+   
Sbjct: 1248 GSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 1307

Query: 88   PAGVESILLTIKDDTIYLTRH--LAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--GL 143
                  I + + + T+ L +      +NG  +  P       I  S   + V      GL
Sbjct: 1308 ---TRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 1364

Query: 144  TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL--SDGVLFSPLEFGNMQKINQ 201
             + ++    + + +   +    CGLCG+YNG     +F   +     +  EFGN  +   
Sbjct: 1365 RVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG-DPKDDFQKPNGSQAGNANEFGNSWEEVV 1423

Query: 202  PDVVCEDP------EEEVAPASCSEHRA--ECERLLTAEAF-----------ADCQDLVP 242
            PD  C  P       E+  P+    H+   E E+    E F           + C  LV 
Sbjct: 1424 PDSPCLPPTPCPPGSEDCIPS----HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVD 1479

Query: 243  LEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPG 302
             +  L+ C  D C   G  + +CS +  +   C  AGG    WRT T          CP 
Sbjct: 1480 PQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETF-----CPMECPP 1534

Query: 303  NLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEG 339
            N  Y      C   CS L     C++   +GC C  G
Sbjct: 1535 NSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSG 1571



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 86/333 (25%), Positives = 124/333 (37%), Gaps = 35/333 (10%)

Query: 33   GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAV---HLKRGPGQAEA 87
            G   C   G+ HY TFDG  F F G C Y  A  C  R     FAV   ++  G G+   
Sbjct: 2449 GSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 2508

Query: 88   PAGVESILLTIKDDTIYLTRH--LAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--GL 143
                  I + + + T+ L +      +NG  +  P       I  S   + V      GL
Sbjct: 2509 ---TRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 2565

Query: 144  TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL--SDGVLFSPLEFGNMQKINQ 201
             + ++    + + +   +    CGLCG+YNG     +F   +     +  EFGN  +   
Sbjct: 2566 RVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG-DPKDDFQKPNGSQAGNANEFGNSWEEVV 2624

Query: 202  PDVVCED------------PEEEVAPASCSEHRAE--CERLLTAEA-FADCQDLVPLEPY 246
            PD  C              P EE  P    +++ E  C  L +     + C  LV  +  
Sbjct: 2625 PDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 2684

Query: 247  LRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVY 306
            L+ C  D C   G  + +CS +  +   C  AGG+   WR  T          CP N  Y
Sbjct: 2685 LKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETF-----CPMECPQNSHY 2739

Query: 307  LESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEG 339
                  C   CS L     C +   +GC C  G
Sbjct: 2740 ELCADTCSLGCSALSAPLQCPDGCAEGCQCDSG 2772



 Score = 79.3 bits (194), Expect = 5e-14
 Identities = 74/323 (22%), Positives = 127/323 (39%), Gaps = 31/323 (9%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVESI 94
            C   G+ HY +FDG  F F G C Y     C    +   F V ++     ++  +   ++
Sbjct: 864  CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923

Query: 95   LLTIKDDTIYLTRHLAVLNGAVV--STPHYSPGLLIEKSDAYTKVYSRA---------GL 143
             +  +   + + R      G V+      Y P    + +D   +V+ +          GL
Sbjct: 924  RVEARGVKVAVRREYP---GQVLVDDVLQYLP---FQAADGQVQVFRQGRDAVVRTDFGL 977

Query: 144  TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL-SDGVLFSPLEFGNM-QKINQ 201
            T+ ++    +  ++ + +    CGLCG++NG  +    L   G   + L FGN  Q+  +
Sbjct: 978  TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETR 1037

Query: 202  PDVVCEDPEE----EVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQDRCR 256
            P     +P +    +   A   + + EC  L   +  F +C   +  +  +R C  DRC 
Sbjct: 1038 PGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL 1097

Query: 257  CPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDT 316
             PG    +C  +A ++  C  AG     WR+           +CP +  Y      C  +
Sbjct: 1098 LPGQSGPLCDALATYAAACQAAGATVHPWRSEEL-----CPLSCPPHSHYEACSYGCPLS 1152

Query: 317  CSHLEVSSLCEEHRMDGCFCPEG 339
            C  L V   C     +GC C EG
Sbjct: 1153 CGDLPVPGGCGSECHEGCVCDEG 1175



 Score = 78.6 bits (192), Expect = 8e-14
 Identities = 86/339 (25%), Positives = 122/339 (35%), Gaps = 47/339 (13%)

Query: 33   GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAV---HLKRGPGQAEA 87
            G   C   G+ HY TFDG  F F G C Y  A  C  R     FAV   ++  G G+   
Sbjct: 3650 GSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 3709

Query: 88   PAGVESILLTIKDDTIYLTRH--LAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--GL 143
                  I + + + T+ L +      +NG  +  P       I  S   + V      GL
Sbjct: 3710 ---TRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 3766

Query: 144  TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL--SDGVLFSPLEFGNMQKINQ 201
             + ++    + + +   +    CGLCG+YNG     +F   +     +  EFGN  +   
Sbjct: 3767 RVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG-DPKDDFQKPNGSQAGNANEFGNSWEEVV 3825

Query: 202  PDVVCEDPEEEVAPASCSEHRAEC----------ERLLTAEAF-----------ADCQDL 240
            PD  C      + P +C    A C          E+    E F           + C  L
Sbjct: 3826 PDSPC------LPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKL 3879

Query: 241  VPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTC 300
            V  +  L+ C  D C   G  + +CS +  +   C  AGG    WR  T          C
Sbjct: 3880 VDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETF-----CPMEC 3934

Query: 301  PGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEG 339
            P N  Y      C   CS L     C +   +GC C  G
Sbjct: 3935 PQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSG 3973



 Score = 36.6 bits (83), Expect = 0.34
 Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 11/92 (11%)

Query: 358  VVVFKSDGSVLL--------NELQVNLP-HVTASFSVFRPSSYHIMVSMAIGVRLQVQLA 408
            V +F  DG V L        N L+V+LP    AS SV R     ++V    GV++ +   
Sbjct: 5294 VHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGAN 5353

Query: 409  PVMQLFVTLDQASQGQVQGLCGNFNGLEGDDF 440
              + + V+ D A  G++ G CGNF+G + +D+
Sbjct: 5354 GKVAVIVSNDHA--GKLCGACGNFDGDQTNDW 5383


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score =  228 bits (580), Expect = 8e-59
 Identities = 221/699 (31%), Positives = 315/699 (45%), Gaps = 127/699 (18%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPT-------PTSTQSTTPTPITTT----TTV 1345
            V      T +TT   T TP+TT+T  + +PT       PTST S   TP+T+     T +
Sbjct: 700  VASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLL 759

Query: 1346 TPTPTPTGTQTP--TTTPITTTTTVTPTPTPT-GTQTPTTTP-------ITTTTTVTPTP 1395
            T +   T + TP  T+T ITT+T  + +PT T GT  P +TP        +   ++TP  
Sbjct: 760  TSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVT 819

Query: 1396 TPTG-----TQTPTSTPITTTTTVTPTPTPT-GTQTPTTT-----------PITTT---- 1434
            +P       T   +++P+TT+T V+ +PTP  GT  PT+T           P++TT    
Sbjct: 820  SPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVAT 879

Query: 1435 ---TTVTPTPTPTGTQAPTPTAI-----TTTSTVTPTPTPTGTQTPTTTPITTTTTVTPT 1486
               +T++ TP  T T     T       T+  T  PT TP    TP T+   +TT V  +
Sbjct: 880  SAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSS 939

Query: 1487 PTPTGTQTP--TPTAITTTTTVTPTPTPT-GTQTPTSTPITTTTTVTPTP--------TP 1535
               T + TP  T T +TT+T  T +PT   GT  PTSTP   TT +T TP        + 
Sbjct: 940  EARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSE 999

Query: 1536 TGTQTPTP----TPISTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTP----------- 1579
              T + TP    TP++T+T   +P PT  GT  PT+TP   +T +T  P           
Sbjct: 1000 ASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSET 1059

Query: 1580 -----TPTGTQTPTTV---LITTTTTMTPTPTPTSTKSTTVTPIT----TTTTVTATPTP 1627
                 TP  T TP T      +++TT   T  PTST S   TP+T    +T  V ++   
Sbjct: 1060 STLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAS 1119

Query: 1628 TGTQTP--TMIPISTTTTVTPTPTPTTGSTGP--PTHTSTAPIAEL---TTSNPPPESST 1680
            T + TP  T IP++T+T  + +PT   G++ P  P    T P+A +   TT     E++T
Sbjct: 1120 TLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANT 1179

Query: 1681 PQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTP-------------TAPTTTSGGHT 1727
              T+   S     ++T  S+ PP  E+TS  P STP               P  +S   T
Sbjct: 1180 LSTTPVDSKTQVATSTEASSPPPTAEVTS-MPTSTPGERSTPLTSMPVRHTPVASSEAST 1238

Query: 1728 LSPPPSTTTSP----PGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLST---PSII 1780
            LS  P  T++P      T +  TT   +S PT +T + +T     P  T L T    S +
Sbjct: 1239 LSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTL 1298

Query: 1781 RTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGD-----TCYFVNCSLSCTLEFYNWS 1835
             TT +      V    V +    A G  +   TY +     T   VN +L  +      S
Sbjct: 1299 LTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILS 1358

Query: 1836 CP----STPSPTPTPSKSTPTPSKPSSTP-SKPTPGTKP 1869
                  STP  T T + S+PT S+ +S P S P+ GT P
Sbjct: 1359 TTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTP 1397



 Score =  218 bits (554), Expect = 8e-56
 Identities = 202/654 (30%), Positives = 292/654 (44%), Gaps = 96/654 (14%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPTP-------TSTQSTTPTPITT----TTTV 1345
            VT P   T +TT   + +P+TT+T V+ +PTP       TST S   TP+T+    TT V
Sbjct: 818  VTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLV 877

Query: 1346 TPTPTPTGTQTP--TTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT---- 1398
              +   T + TP  T+TP+T +T    +PT + GT  PT+TP   +T +T  P  T    
Sbjct: 878  ATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVV 937

Query: 1399 --------GTQTPTSTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQAP 1449
                     T   TSTP+TT+T  T +PT   GT  PT+TP   TT +T TP      + 
Sbjct: 938  SSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPV-----SH 992

Query: 1450 TPTAITTTSTVTPTPTPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTPTAITTTT 1504
            T  A +  ST++ TP  + T   T+T     P T   T  PT TP+   TP      +TT
Sbjct: 993  TLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTT 1052

Query: 1505 TVTPTPTPTGTQTP--TSTPITT-------TTTVTPTPTPTGTQTPTPTPISTTTTVTPT 1555
             V  + T T + TP  TSTP+TT       +TT   T  PT T +   TP+++    T  
Sbjct: 1053 MVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRL 1112

Query: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTP----TPTPTSTKSTT 1611
               +   T +TTP+ T+  V  T +   + +PTT   T+  T  P    TP  +   STT
Sbjct: 1113 VVSSEASTLSTTPVDTSIPV--TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTT 1170

Query: 1612 VTPITTTTTVTATPTPTGTQTPTMIPIST---TTTVTPTPTPTTGSTGPP------THTS 1662
            +   +   T++ TP  + TQ  T    S+   T  VT  PT T G    P       HT 
Sbjct: 1171 LVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTP 1230

Query: 1663 TAPIAELTTSNPPPESSTPQT--SRSTSSPLT------------ESTTLLSTLPPAIEMT 1708
             A     T S  P ++STP T  + ++SSP T            E +TLL+++P +  + 
Sbjct: 1231 VASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLV 1290

Query: 1709 STAPPST-------PTAPTTTSGGHTLSPPPSTTTS-PPGTPTRGTTTGSSSAPTPSTVQ 1760
            ++   ST          P  TS   + SP P+  TS P  T + G T  +S     + V 
Sbjct: 1291 TSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVA 1350

Query: 1761 TTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYF 1820
            ++  S  + TP   STP +  +T     P++       ++    P      GT   T   
Sbjct: 1351 SSAISILSTTPVDNSTP-VTTSTEACSSPTT-------SEGTSMPNSNPSEGTTPLTSIP 1402

Query: 1821 VNCSLSCTLEFYNWSC----PSTPSPTPTPSKSTPTPSKPSSTP-SKPTPGTKP 1869
            V+ +   + E    S      STP  T   + S+PT ++  S P S P+ G  P
Sbjct: 1403 VSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTP 1456



 Score =  218 bits (554), Expect = 8e-56
 Identities = 203/640 (31%), Positives = 285/640 (44%), Gaps = 122/640 (19%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPTPT-------STQSTTPTPIT----TTTTV 1345
            V  P   T +TT   + +P+ T+T V+ +PTP        ST S   TP+T    +TT V
Sbjct: 3058 VAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPV 3117

Query: 1346 TPTPTPTGTQTP--TTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT---- 1398
            T +   T + TP  T+TP+TT+T    +PT + GT  PT+TP   +T +T  P  T    
Sbjct: 3118 TSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVV 3177

Query: 1399 --------GTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPT 1450
                     T   TSTP+TT+T  T + T  GT  PT+TP    T +T  P      A +
Sbjct: 3178 SSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASS 3237

Query: 1451 PTAITTTSTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPT 1509
              +I +T+ V + TP  T T+  +++P T   T  PT TP+   TP  +   +TTTV  +
Sbjct: 3238 EASILSTTPVDSNTPLTTSTEA-SSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASS 3296

Query: 1510 PTPTGTQTP--TSTPITTTTTVTPTP-------TPTGTQTPTPTPIS----TTTTVTPTP 1556
             T T + TP  TSTP+TT +  + +P        PT T +   TP++    +TT V  + 
Sbjct: 3297 ETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSE 3356

Query: 1557 TPTGTQTP--TTTPITTTTTVTPTPTPT-GTQTPTTVLITTTTTMTPTPTPTSTKSTTVT 1613
              T + TP  T+TP+TT+T  + +PT   GT  PT+     TT +   P      STT  
Sbjct: 3357 ASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPV-----STTPV 3411

Query: 1614 PITTTTTVTATPTPTGTQTPTMIPISTTTTV---TPTPTPTTGSTGPPTH---TSTAPIA 1667
              +   T++ TP  + T   T    S++ T+   T  PT TT     P      ST P+A
Sbjct: 3412 VSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVA 3471

Query: 1668 E---LTTSNPPPESSTPQTSRS--TSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT 1722
                 T S  P ++STP T+ S   SSP T   T + T       ++    STP      
Sbjct: 3472 SSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPT-------STAGEGSTPLTNMPV 3524

Query: 1723 SGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRT 1782
            S     S   ST ++ P       T+ S ++ +P+T+Q TT          +STPS    
Sbjct: 3525 STTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMR--------MSTPS---- 3572

Query: 1783 TGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPS- 1841
                   SS L   +L+ TY    E                           S PSTPS 
Sbjct: 3573 -----EGSSSLTTMLLSSTYVTSSEA--------------------------STPSTPSV 3601

Query: 1842 ------PTPTPSKSTPTPSK----PSSTPSK-PTPGTKPP 1870
                   T T S STPTP +    P STPS+  TP T  P
Sbjct: 3602 DRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMP 3641



 Score =  217 bits (553), Expect = 1e-55
 Identities = 201/663 (30%), Positives = 292/663 (44%), Gaps = 94/663 (14%)

Query: 1298 TQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPT-----PITTTTTVTPTPTPT 1352
            ++ +T+ T+   + TP   +  +T++ TP  TS   TT T     P T   T  P  TP+
Sbjct: 2865 SEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPS 2924

Query: 1353 GTQTPTTTPITTTTTV------TPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG 1399
               TP T+ + +T  V      T + TP  T+TP TT       P T   T  P  TP  
Sbjct: 2925 EVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGE 2984

Query: 1400 TQTPTSTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTP---TGTQAPTPTAI 1454
             +TP ++   +T  V  +   T ++TP  T+TP+TT+T  + +PT    TG    TP+  
Sbjct: 2985 RRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEG 3044

Query: 1455 TTTST-----VTPTPTPTGTQTPTT-----TPITTTTTVTPTPTPT-GTQTPTPT----- 1498
            +T  T      TP   P  +   TT     +P+ T+T V+ +PTP  GT  P  T     
Sbjct: 3045 STPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGS 3104

Query: 1499 -----AITTTTTVTPTPTPTGTQTP--TSTPITTTTTVTPTPTPT-GTQTPTPTPISTTT 1550
                    +TT VT +   T + TP  TSTP+TT+T    +PT + GT  PT TP   +T
Sbjct: 3105 TPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGST 3164

Query: 1551 TVTPTPTPT------------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTM 1598
             +T  P  T             T   T+TP+TT+T  T + T  GT  PT+      T +
Sbjct: 3165 PLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPL 3224

Query: 1599 TPTPTPTSTKSTTVTPITTTTTVTA-TPTPTGTQTPTMIPISTTTTVTPTPTPTTGS--- 1654
            T  P   +  +++   I +TT V + TP  T T+  +  P +  T++ PT TP+ GS   
Sbjct: 3225 TSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSM-PTSTPSEGSTPL 3283

Query: 1655 TGPPTHTSTAPIAELTT-SNPPPESSTPQT--SRSTSSPLTESTTLLSTLPPAIEMTSTA 1711
            T  P  T+T   +E +T S  P ++STP T  S+++SSP     T + T   +   T   
Sbjct: 3284 TSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLT 3343

Query: 1712 PPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRG----TTTGSSSAPTPSTVQTTTTSAW 1767
              S  T P  +S   TLS  P  T++P  T T      TT   +S PT S  + TT  A 
Sbjct: 3344 NMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLAS 3403

Query: 1768 TPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSC 1827
             P  T     S + T    P  S+ L   V   T  +    +  GT   T      S   
Sbjct: 3404 MPVSTTPVVSSEVNTLSTTPVDSNTL---VTTSTEASSSPTIAEGTSLPTSTTSEGSTPL 3460

Query: 1828 TL-----------EFYNWSC----PSTPSPTPTPSKSTPTPSKPSSTPSK-----PTPGT 1867
            ++           E    S      STP  T +P+ S+PT ++ +S P+       TP T
Sbjct: 3461 SIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLT 3520

Query: 1868 KPP 1870
              P
Sbjct: 3521 NMP 3523



 Score =  214 bits (545), Expect = 9e-55
 Identities = 210/667 (31%), Positives = 297/667 (44%), Gaps = 112/667 (16%)

Query: 1298 TQPTTMTTTTTENPTPTPITT-----TTTVTPTPTPTSTQSTTPTPITT----TTTVTPT 1348
            ++ +T++TT  ++ TP   +T     +TT   T  PTST +   TP+T+    TT V  +
Sbjct: 644  SEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASS 703

Query: 1349 PTPTGTQTP--TTTPITTTTTVTPTPT-------PTGTQTPTTTPITTT----TTVTPTP 1395
               T + TP  T+TP+TT+T  + +PT       PT T +  +TP+T+     T +T + 
Sbjct: 704  EASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSE 763

Query: 1396 TPTGTQTP--TSTPITTTTTVTPTPTPT-GTQTPTTTP-------ITTTTTVTPTPTP-T 1444
              T + TP  TST ITT+T  + +PT T GT  P +TP        +   ++TP  +P  
Sbjct: 764  ASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEA 823

Query: 1445 GTQAPTP----TAITTTSTVTPTPTPT-GTQTPTTT-----------PITTTTTVTPT-P 1487
             T + TP    + +TT++ V+ +PTP  GT  PT+T           P++TT   T    
Sbjct: 824  STLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAIS 883

Query: 1488 TPTGTQTPTPTAITTTTTVTPTPTPT-GTQTPTSTPITTTTTVTPTPTPT---------- 1536
            T + T   T T +T +T    +PT + GT  PTSTP   +T +T  P  T          
Sbjct: 884  TLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEART 943

Query: 1537 --GTQTPTPTPISTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTP-------------- 1579
               T   T TP++T+T  T +PT   GT  PT+TP   TT +T TP              
Sbjct: 944  LSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTL 1003

Query: 1580 --TPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIP 1637
              TP  + TP T   T+T   +P PT   T   T TP   +T +T  P  T     TM+ 
Sbjct: 1004 STTPVDSNTPLT---TSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVST-----TMVA 1055

Query: 1638 ISTTTTVTPTP----TPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTE 1693
             S T+T++ TP    TP T  +   + ++TA    + TS    E STP TS   S+ L  
Sbjct: 1056 SSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTST-YSEGSTPLTSVPVSTRLVV 1114

Query: 1694 ST--TLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSP-PGTPTRGTTTGS 1750
            S+  + LST P    +  T      ++PTT  G    + PPS  T+P    P   T   S
Sbjct: 1115 SSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVS 1174

Query: 1751 SSAPTPSTVQ-------TTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYY 1803
            S A T ST          T+T A +P PT   T     T G R  P   L    +  T  
Sbjct: 1175 SEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTP---LTSMPVRHTPV 1231

Query: 1804 APGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSK-PSSTPSK 1862
            A  E     T       V+ S   T      S P+T   T  P+ +T   S   +S P  
Sbjct: 1232 ASSEASTLSTSP-----VDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVS 1286

Query: 1863 PTPGTKP 1869
             T  T P
Sbjct: 1287 TTLVTSP 1293



 Score =  214 bits (544), Expect = 1e-54
 Identities = 206/646 (31%), Positives = 299/646 (46%), Gaps = 100/646 (15%)

Query: 1301 TTMTTTTTENPTPTPITTTTTVTPTPT-------PTSTQSTTPTPITT----TTTVTPTP 1349
            +T++TT  +N TP  +TT+T    +PT       P ST S   TP+T+    TT V  + 
Sbjct: 1708 STLSTTPVDNSTP--VTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSE 1765

Query: 1350 TPTGTQTP--TTTPITTTTTVTPTPT-------PTGTQTPTTTPITTT----TTVTPTPT 1396
              T + TP  T+TP+TT+T  T +PT       PT T +   TP+T+T    T V  +  
Sbjct: 1766 ASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEA 1825

Query: 1397 PTGTQTP--TSTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQAPTPT- 1452
             T + TP  +++P+ T+T V+ +PTP  GT   T+TP   +T +T  P  T T A + T 
Sbjct: 1826 STLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETN 1885

Query: 1453 AITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTP-- 1510
             ++TT  VT TP  T  Q  +++P T   +  PT TP   + P  +   +TTTV  +   
Sbjct: 1886 TLSTTPAVTSTPVTTYAQV-SSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEIN 1944

Query: 1511 TPTGTQTPTSTPITTTTTVTPTPTPT-GTQTPTPT-----------PISTTTTV-----T 1553
            T + T   T TP+TT +  + +PT   GT  PTP            P+STT  V     T
Sbjct: 1945 TLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEAST 2004

Query: 1554 PTPTPTGTQTPTTT-------PITTTTTVTPTPTPTGTQTPTTVLITTTT--------TM 1598
             + TP  T TP TT       P T   T   T TP+   TP   +  +TT        T+
Sbjct: 2005 LSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTL 2064

Query: 1599 TPTPTPTSTKSTTVTPITTTTT-----VTATPTPTGTQTPTMIPISTTTTVTP---TPTP 1650
            + TP  + T+ T  T  +++ T     +T +    G+   T IP+STT   +P   T + 
Sbjct: 2065 STTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLST 2124

Query: 1651 TTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTS--SPLTE---STTLLSTLPPAI 1705
            T   +  P  TST    E+++S  P E ++ QTS  +   +PLT    STT++++   AI
Sbjct: 2125 TPVDSNSPVITST----EVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVAS--SAI 2178

Query: 1706 EMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTS-PPGTPTRGTTTGSSSAPTPSTVQTTTT 1764
               ST P  T T P T S     SP  S  TS P  TP+ G+T  +S   +   V T+  
Sbjct: 2179 STLSTTPVDTST-PVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEA 2237

Query: 1765 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
            S  + TP   STP +  +T     P++        +    P   +  GT   T   V+ +
Sbjct: 2238 STLSATPVDTSTP-VTTSTEATSSPTTA-------EGTSIPTSTLSEGTTPLTSIPVSHT 2289

Query: 1825 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPP 1870
            L    E       ST S TP  S +  T S  +S+P     GT  P
Sbjct: 2290 LVANSEV------STLSTTPVDSNTPFTTSTEASSPPPTAEGTSMP 2329



 Score =  214 bits (544), Expect = 1e-54
 Identities = 198/660 (30%), Positives = 290/660 (43%), Gaps = 109/660 (16%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPT-------PTSTQSTTPTPITTT----TTV 1345
            V      T +TT   T  P+TT+T  + +PT       PTST S T TP+T+     T V
Sbjct: 2763 VASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPV 2822

Query: 1346 TPTPTPTGTQTP--TTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQT 1402
              +   T + TP  T+TP+TT+T  + +PT   G   P +T    +T +T  P  T    
Sbjct: 2823 ASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVST---- 2878

Query: 1403 PTSTPITTTTTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTGTQAPTPTAIT 1455
               TP+ ++   T + TP  T  P TT       P T   T  P  TP+    P  + + 
Sbjct: 2879 ---TPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILV 2935

Query: 1456 TTSTV------TPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTGTQTPT------ 1496
            +T  V      T + TP  T+TP TT       P T   T  P  TP   +TP       
Sbjct: 2936 STVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVS 2995

Query: 1497 --PTAITTTTTVTPTPTPTGTQTPTST-----PITTTTTVTPTPTPTGTQTP-TPTPIST 1548
              P A +  +T++ TP  T T   TST     P T   T  P  TP+   TP T  P+ST
Sbjct: 2996 TMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVST 3055

Query: 1549 TTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTVLITTTTTMTPTPTPTS 1606
            T    P   T + T   + +P+ T+T V+ +PTP  GT  P +     +T +T  P  T+
Sbjct: 3056 TPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTT 3115

Query: 1607 -TKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAP 1665
               S+ ++ ++TT   T+TP  T T+  +  P ++  T  PT TP+ GST P T+   + 
Sbjct: 3116 PVTSSAISTLSTTPVDTSTPVTTSTEAHSS-PTTSEGTSMPTSTPSEGST-PLTYMPVST 3173

Query: 1666 I-----AELTTSNPPPESSTPQT--SRSTSSPLTESTTLLSTLPP--AIEMTSTAPPSTP 1716
            +      + T S  P ++STP T  + +TSS   E T++ ++ P      +TS    +TP
Sbjct: 3174 MLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTP 3233

Query: 1717 TA----------------PTTTSGGHTLSPPPSTTTS-PPGTPTRGTTTGSSSAPTPSTV 1759
             A                P TTS   + SPP +  TS P  TP+ G+T  +S   + +TV
Sbjct: 3234 VASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTV 3293

Query: 1760 QTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGD-TC 1818
             ++ TS  + TP   STP    +      P              A G  +   TY + + 
Sbjct: 3294 ASSETSTLSTTPADTSTPVTTYSQASSSPP-------------IADGTSMPTSTYSEGST 3340

Query: 1819 YFVNCSLSCTLEFYNWSC--------PSTPSPTPTPSKSTPTPSKPSSTP-SKPTPGTKP 1869
               N S S T    + +          STP  T T +  +PT ++ +S P S P+ GT P
Sbjct: 3341 PLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTP 3400



 Score =  212 bits (540), Expect = 3e-54
 Identities = 205/674 (30%), Positives = 295/674 (43%), Gaps = 123/674 (18%)

Query: 1304 TTTTTENPTPTPITTTTTVTPTPTPTSTQSTTP----TPITTTTTVTPTPT-PTGTQTPT 1358
            T+T +E  TP    + +T+    +  ST STTP    TP+TT++  + + T P GT  PT
Sbjct: 503  TSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPT 562

Query: 1359 TTPITTTTTVTPTPTPTG------TQTPTTTPITTTTTVTPTP-------TPTGTQTPTS 1405
            +TP   +T +T  P  T         T +TTP  + T VT +        T  GT  PTS
Sbjct: 563  STPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTS 622

Query: 1406 TPITTTTTVTP----------------TPTPTGTQTPTTTPI-----TTTTTVTPTPTPT 1444
            T     TT+T                 + TP  + TP TT       +TT   T  PT T
Sbjct: 623  TYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTST 682

Query: 1445 GTQAPTP--------TAITTTSTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTP 1489
             T+  TP        T + ++   T + TP  T TP TT       P T      PT TP
Sbjct: 683  YTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTP 742

Query: 1490 TGTQTPTPTAITTTTTVTPTPTPTGTQTP--TSTPITTTTTVTPTPTPT-GTQTPTPTP- 1545
            +   TP  +   + T +T +   T + TP  TST ITT+T  + +PT T GT  P  TP 
Sbjct: 743  SEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPS 802

Query: 1546 ------ISTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTPT-GTQTPTTVLIT 1593
                   S   ++TP  +P  +   TT     +P+TT+T V+ +PTP  GT  PT+    
Sbjct: 803  EGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSE 862

Query: 1594 TTTTMTPTPTPTSTKSTT-VTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTT 1652
              T +T  P  T+  +T+ ++ ++TT   T+TP    T+  +  P ++  T  PT TP  
Sbjct: 863  GRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSS-PTTSEGTSMPTSTPGE 921

Query: 1653 GSTG----PPTHTSTAPIAELTTSNPPPESSTPQT--SRSTSSPLT------------ES 1694
            GST     P + T        T S  P ++STP T  + +TSSP T            E 
Sbjct: 922  GSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEG 981

Query: 1695 TTLLSTLPPAIEMTSTAPPST-------PTAPTTTSGGHTLSPPPST--TTSPPGTPTRG 1745
            TT L++ P +  + + +  ST          P TTS     SPPP+   T+ P  TP+ G
Sbjct: 982  TTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTS-TEASSPPPTAEGTSMPTSTPSEG 1040

Query: 1746 TTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAP 1805
            +T  +    + + V ++ TS  + TP   STP    TT  +   SS            A 
Sbjct: 1041 STPLTRMPVSTTMVASSETSTLSTTPADTSTPV---TTYSQASSSSTT----------AD 1087

Query: 1806 GEEVYNGTYGD-----TCYFVNCSLSCTLEFYNWSC----PSTPSPTPTPSKSTPTPSKP 1856
            G  +   TY +     T   V+  L  + E    S      S P  T T + S+PT ++ 
Sbjct: 1088 GTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEG 1147

Query: 1857 SSTP-SKPTPGTKP 1869
            +S P S P+ GT P
Sbjct: 1148 TSIPTSPPSEGTTP 1161



 Score =  209 bits (532), Expect = 3e-53
 Identities = 218/768 (28%), Positives = 333/768 (43%), Gaps = 92/768 (11%)

Query: 1164 STLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTP-KLCCLWSDWINEDHPSSGSDDG 1222
            S + T T ++   TP   T+   +T    ST L++ P     + S  IN    +      
Sbjct: 1484 SPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTST 1543

Query: 1223 DRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQKPGGVIPMA 1282
               T+     +P   +  S++    S    G        VS  L+  +E        P+ 
Sbjct: 1544 PVTTYSQASSSPTTADGTSMQT---STYSEGSTPLTSLPVSTMLVVSSEANTLS-TTPID 1599

Query: 1283 FCLNYEINVQCCECVT-QPTTMTTTTTENPTPTPITTTTTVTPTPTP-TSTQSTTP---- 1336
                   + +     T + ++MT +T    +P   +   + TP  +P  ST STTP    
Sbjct: 1600 SKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSN 1659

Query: 1337 TPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1395
            +P+ T+T V+ +PTP  GT  PT+T        T   TP  + T  TTP+ ++   T + 
Sbjct: 1660 SPVITSTEVSSSPTPAEGTSMPTST-------YTEGRTPLTSITVRTTPVASSAISTLST 1712

Query: 1396 TPTGTQTPTSTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAI 1454
            TP        TP+TT+T    +PT + GT  P +TP   TT +T  P  T     TP   
Sbjct: 1713 TPVDNS----TPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVST-----TPVLS 1763

Query: 1455 TTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTPTAITTTTTVTPTP--- 1510
            +  ST++ TP        T+TP+TT+T  T +PT   GT  PT T     T +T TP   
Sbjct: 1764 SEASTLSATP------IDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSH 1817

Query: 1511 ---------TPTGTQTPTSTPITTTTTVTPTPTPT-GTQTPTPTPIS----------TTT 1550
                     T + T   +++P+ T+T V+ +PTP  GT   T TP            +TT
Sbjct: 1818 TLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTT 1877

Query: 1551 TVTPTPTPTGTQTP--TTTPITTTTTVTPTPTPT-GTQTPTTVLITTTTTMTPTPTPTST 1607
            TV  + T T + TP  T+TP+TT   V+ +PT   G+  PT+        +T  P  T+T
Sbjct: 1878 TVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTT 1937

Query: 1608 -KSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGS---TGPPTHTST 1663
              S+ +  ++TT   T TP  T +Q  +  P +   T  PTP  + GS   T  P  T+ 
Sbjct: 1938 VASSEINTLSTTLADTRTPVTTYSQASSS-PTTADGTSMPTPAYSEGSTPLTSMPLSTTL 1996

Query: 1664 APIAELTT-SNPPPESSTPQT--SRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPT 1720
               +E +T S  P ++STP T  +  +SSP T   T + T  P+   T  A     T   
Sbjct: 1997 VVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLV 2056

Query: 1721 TTSGGHTLSPPP----STTTSPPGTPTRGTTTGSS---SAPTPSTVQTTTTSAWTPTPTP 1773
             +S G+TLS  P    +  T+     +  T  GSS   SAP+  +   T+    T   TP
Sbjct: 2057 VSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLST---TP 2113

Query: 1774 LSTP--SIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGD-----TCYFVNCSLS 1826
            +++P  S + TT +      +    V +      G  +   TY D     T   V+ ++ 
Sbjct: 2114 VASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVV 2173

Query: 1827 CTLEFYNWSC----PSTPSPTPTPSKSTPTPSKPSSTP-SKPTPGTKP 1869
             +      S      STP    T ++S+PT S+ +S P S P+ G+ P
Sbjct: 2174 ASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTP 2221



 Score =  208 bits (529), Expect = 6e-53
 Identities = 211/675 (31%), Positives = 303/675 (44%), Gaps = 138/675 (20%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPTPT-------STQSTTPTPITT----TTTV 1345
            V  P   T +TT   + +P+ T+T V+ +P PT       ST S   TP+T+    TT V
Sbjct: 2114 VASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVV 2173

Query: 1346 TPTPTPTGTQTP--TTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT---- 1398
              +   T + TP  T+TP+T +T    +PT + GT  PT+TP   +T  T  P  T    
Sbjct: 2174 ASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVV 2233

Query: 1399 --------GTQTPTSTPITTTTTVTPTPT-------PTGTQTPTTTPIT----------- 1432
                     T   TSTP+TT+T  T +PT       PT T +  TTP+T           
Sbjct: 2234 TSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVAN 2293

Query: 1433 ---TTTTVTP----TPTPTGTQA--PTPTAITT---TSTVTPTPTPTGTQTPTTTPITTT 1480
               +T + TP    TP  T T+A  P PTA  T   TST +   TP      +TT + + 
Sbjct: 2294 SEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASF 2353

Query: 1481 TTVTPTPTPTGTQTPTPT---AITTTTTVTPTPTPTGTQTPTSTPIT----TTTTVTPTP 1533
             T T + TP  T TP  T   A ++ TT   T  PT T +  STP+T    +T  V  + 
Sbjct: 2354 ETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSE 2413

Query: 1534 TPTGTQTP--TPTPISTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTV 1590
              T + TP  T TP++T+T  + +PT   GT  PT+ P   TT +   P  T     T V
Sbjct: 2414 ASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVST-----TPV 2468

Query: 1591 LITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPIST----TTTVTP 1646
            + +   T++ TP  TS      TP+TT+T  +++PT   T    ++PIST    +T +T 
Sbjct: 2469 VSSEAGTLSTTPVDTS------TPMTTSTEASSSPT---TAEDIVVPISTASEGSTLLTS 2519

Query: 1647 TPTPTTGSTGPPTHT-STAPIAELTTSNPPPESSTPQTSRSTS--------SPLTESTTL 1697
             P  TT    P   T ST P+     SN P  +ST  +S +TS        S  +E +T 
Sbjct: 2520 IPVSTTPVASPEASTLSTTPV----DSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTP 2575

Query: 1698 LSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPS 1757
            L ++P      ST P ++  A T ++     S P +T+T    +PT    T S    TPS
Sbjct: 2576 LRSMP-----VSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDT-SMPISTPS 2629

Query: 1758 TVQTTTTS------------AWTPTPTPLSTPSIIRT-TGLRPYPSSVLICCVLNDTYYA 1804
             V T+ TS            A T + TP+ T +++ T TG    P++            A
Sbjct: 2630 EVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTT------------A 2677

Query: 1805 PGEEVYNGTYGD-----TCYFVNCSLSCTLEFYNWSC----PSTPSPTPTPSKSTPTPSK 1855
             G  +   T G+     T   V+ +L    E    S      STP  T   + S+PT ++
Sbjct: 2678 EGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAE 2737

Query: 1856 PSSTP-SKPTPGTKP 1869
             +S   S P+ G+ P
Sbjct: 2738 GTSMRISTPSDGSTP 2752



 Score =  206 bits (525), Expect = 2e-52
 Identities = 207/666 (31%), Positives = 295/666 (44%), Gaps = 114/666 (17%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTT-------TTVTPTPTPTSTQSTTPTPITT----TTTV 1345
            V      TT+TT   + T +TT+       TT   T  PTST S   T IT+    TT V
Sbjct: 582  VVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLV 641

Query: 1346 TPTPTPTGTQTP--TTTPITTTTTVTPTPT-------PTGTQTPTTTPITT----TTTVT 1392
              +   T + TP  + TP+TT+T  T + T       PT T T  +TP+T+    TT V 
Sbjct: 642  ASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVA 701

Query: 1393 PTPTPTGTQTP--TSTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTP-------- 1441
             +   T + TP  TSTP+TT+T  + +PT   G   PT+TP   +T +T  P        
Sbjct: 702  SSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTS 761

Query: 1442 ----TPTGTQAPTPTAITTTSTVTPTPTPT-GTQTPTTTP-------ITTTTTVTPTPTP 1489
                T + T   T T ITT++  + +PT T GT  P +TP        +   ++TP  +P
Sbjct: 762  SEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSP 821

Query: 1490 -TGTQTPTP----TAITTTTTVTPTPTPT-GTQTPTST-----------PITTTTTVTPT 1532
               T + TP    + +TT+T V+ +PTP  GT  PTST           P++TT   T  
Sbjct: 822  EASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSA 881

Query: 1533 -PTPTGTQTPTPTPISTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTV 1590
              T + T   T TP++ +T    +PT + GT  PT+TP   +T +T  P  T     T V
Sbjct: 882  ISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDST-----TPV 936

Query: 1591 LITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPT-GTQTPTMIPISTTTTVTPTPT 1649
            + +   T++ TP  TS      TP+TT+T  T++PT   GT  PT  P   TT +T TP 
Sbjct: 937  VSSEARTLSATPVDTS------TPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPV 990

Query: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQT--SRSTSSPLTESTTLLSTLPPAIEM 1707
                     +HT  A     T S  P +S+TP T  + ++S P T   T + T  P+   
Sbjct: 991  ---------SHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGS 1041

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGT----PTRGTTTGSSSAPTPSTVQTTT 1763
            T        T    +S   TLS  P+ T++P  T     +  TT   +S PT +  + +T
Sbjct: 1042 TPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGST 1101

Query: 1764 TSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICC---VLNDTYYAPGEEVYNGTYGD-TCY 1819
                 P  T L   S   T    P  +S+ +       +    A G  +      + T  
Sbjct: 1102 PLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTP 1161

Query: 1820 FVNCSLSCTLEFYNWSCPSTPSPTPTPSK---------STPTP-----SKPSSTP-SKPT 1864
              +  +S TL     S  +T S TP  SK         S+P P     S P+STP  + T
Sbjct: 1162 LASMPVSTTLVVS--SEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERST 1219

Query: 1865 PGTKPP 1870
            P T  P
Sbjct: 1220 PLTSMP 1225



 Score =  205 bits (522), Expect = 4e-52
 Identities = 204/644 (31%), Positives = 287/644 (44%), Gaps = 98/644 (15%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQ------STTPTPITTTTTVTPTPT 1350
            V   T +TT +  + +PT    T+  T TP+  ST       STTP   +  + ++ TP 
Sbjct: 418  VDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPV 477

Query: 1351 PTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-- 1403
             + TQ  T+T     P T      PT TP+   TP T+   +T  V  +   T + TP  
Sbjct: 478  DSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVD 537

Query: 1404 TSTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPT--------GTQAPTP--- 1451
            TSTP+TT++  + + T P GT  PT+TP   +T +T  P  T         T + TP   
Sbjct: 538  TSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADS 597

Query: 1452 -TAITTTSTVTPTPTPT-GTQTPTTTPITTTTTVTP----------------TPTPTGTQ 1493
             T +TT+S  + + T   GT  PT+T     TT+T                 + TP  + 
Sbjct: 598  NTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSN 657

Query: 1494 TPTPT---AITTTTTVTPTPTPTGTQTPTSTPITT----TTTVTPTPTPTGTQTP--TPT 1544
            TP  T   A +++TT   T  PT T T  STP+T+    TT V  +   T + TP  T T
Sbjct: 658  TPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTST 717

Query: 1545 PISTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPT 1603
            P++T+T  + +PT   G   PT+TP   +T +T  P      + T +  +  +T++ TP 
Sbjct: 718  PVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPV-----SKTLLTSSEASTLSTTPL 772

Query: 1604 PTSTKSTTVTPITTTTTVTATPTPT-GTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHT- 1661
             TST       ITT+T  + +PT T GT  P   P   +  +T  P   T  T P   T 
Sbjct: 773  DTSTH------ITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTL 826

Query: 1662 STAPI---AELTTSNPPPESSTPQ--TSRSTS------SPLTE---STTLLSTLPPAIEM 1707
            ST P+   + +TTS     S TP   TS  TS      +PLT    STTL++T   AI  
Sbjct: 827  STTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVAT--SAIST 884

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTS-PPGTPTRGTTTGSSSAPTPSTVQTTTTSA 1766
             ST P  T T P T S     SP  S  TS P  TP  G+T  +S   + + V ++    
Sbjct: 885  LSTTPVDTST-PVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEART 943

Query: 1767 WTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLS 1826
             + TP   STP +  +T     P++     +   T   P E    GT   T   V+ +L 
Sbjct: 944  LSATPVDTSTP-VTTSTEATSSPTTAEGTSIPTST---PSE----GTTPLTSTPVSHTLV 995

Query: 1827 CTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPP 1870
               E       ST S TP  S +  T S  +S+P     GT  P
Sbjct: 996  ANSE------ASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMP 1033



 Score =  203 bits (517), Expect = 2e-51
 Identities = 193/668 (28%), Positives = 282/668 (42%), Gaps = 113/668 (16%)

Query: 1295 ECVTQPTTMTTTTTENPTPTPITTTTTVTPTPT------PTSTQSTTP----TPITTTTT 1344
            E  + PTT   T+    TP+  +T  T  P  T        ST S TP    TP+TT+T 
Sbjct: 3141 EAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTE 3200

Query: 1345 VTPTPTPTGTQTPTTTPITTTTTVTPTP----------------TPTGTQTPTTT----- 1383
             T + T  GT  PT+TP    T +T  P                TP  + TP TT     
Sbjct: 3201 ATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEAS 3260

Query: 1384 --PITTTTTVTPTPTPTGTQTP-TSTPITTTT-----TVTPTPTPTGTQTPTTTPITTTT 1435
              P T   T  PT TP+   TP TS P++TTT     T T + TP  T TP TT    ++
Sbjct: 3261 SSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASS 3320

Query: 1436 TV-----TPTPTPTGTQAPTP--------TAITTTSTVTPTPTPTGTQTPTTT------- 1475
            +      T  PT T ++  TP        T + ++   T + TP  T TP TT       
Sbjct: 3321 SPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLS 3380

Query: 1476 PITTTTTVTPTPTPTGTQTP--------TPTAITTTTTVTPTPTPTGTQTPTSTPITTTT 1527
            P T   T  PT +P+   TP        TP   +   T++ TP  + T   TST  +++ 
Sbjct: 3381 PTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSP 3440

Query: 1528 TV---TPTPTPTGTQTPTP--------TPISTTTTVTPTPTPTGTQTPTTT-------PI 1569
            T+   T  PT T ++  TP        TP++++   T + TP  T TP TT       P 
Sbjct: 3441 TIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPT 3500

Query: 1570 TTTTTVTPTPTPTGTQTPTTVLITTTT--------TMTPTP-------TPTSTKSTTVTP 1614
            T   T  PT T     TP T +  +TT        T++ TP       T +S  S++   
Sbjct: 3501 TAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPAT 3560

Query: 1615 ITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNP 1674
            +  TT   +TP+   +   TM+  ST  T +   TP+T S    T  +T+  +  T + P
Sbjct: 3561 LQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPP 3620

Query: 1675 PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSP-PPS 1733
               +    T    S+PLT      +++  +   T++  P   + P  TS   + SP  P 
Sbjct: 3621 EVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPE 3680

Query: 1734 TTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVL 1793
             TT P  TP+ G+T         +T+  +TT   +   + LSTPS++ +T +     ++ 
Sbjct: 3681 GTTMPIWTPSEGST-------PLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAIS 3733

Query: 1794 ICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTP 1853
                L+ T  +    +   T G T   +  S +    F   S PS PS     S S  T 
Sbjct: 3734 SSATLDSTTMSVSMPMEISTLGTT---ILVSTTPVTRFPESSTPSIPS--VYTSMSMTTA 3788

Query: 1854 SKPSSTPS 1861
            S+ SS+P+
Sbjct: 3789 SEGSSSPT 3796



 Score =  202 bits (513), Expect = 5e-51
 Identities = 193/642 (30%), Positives = 281/642 (43%), Gaps = 81/642 (12%)

Query: 1304 TTTTTENPTPTPITTTTTVTPTPT-------PTSTQSTTPTPITTT----TTVTPTPTPT 1352
            T + T   T TP+TT+T  T +PT       PTST S   TP+T+T    T V  +   T
Sbjct: 1768 TLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEAST 1827

Query: 1353 GTQTP--TTTPITTTTTVTPTPTPT-GTQTPTTTPI----------TTTTTVTPTPTPTG 1399
             + TP  + +P+ T+T V+ +PTP  GT   T+TP            +TTTV  + T T 
Sbjct: 1828 LSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTL 1887

Query: 1400 TQTP--TSTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQAPTP-TAIT 1455
            + TP  TSTP+TT   V+ +PT   G+  PT+TP      +T  P  T T A +    ++
Sbjct: 1888 STTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLS 1947

Query: 1456 TTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGT 1515
            TT   T TP  T +Q  +++P T   T  PTP  +   TP  +   +TT V  +   T +
Sbjct: 1948 TTLADTRTPVTTYSQA-SSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLS 2006

Query: 1516 QTP--TSTPITTTTTVTPTPTPT-GTQTPTPTPISTTTTVTPTPTPTGT------QTPTT 1566
             TP  TSTP TT+T  + +PT   GT   T TP   TT +   P  T         T +T
Sbjct: 2007 TTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLST 2066

Query: 1567 TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPT 1626
            TP+ + T VT +   + + T     +T +     +P  TS   +T TP+ +    T + T
Sbjct: 2067 TPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLST-TPVASPEASTLSTT 2125

Query: 1627 PTGTQTPTMIPISTTTTVTPTPTPTTG---------------STGPPTHTSTAPIAELTT 1671
            P  + +    P+ T+T V+ +P PT G               ++ P + T  A  A  T 
Sbjct: 2126 PVDSNS----PVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTL 2181

Query: 1672 SNPPPESSTPQT--SRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLS 1729
            S  P ++STP T  + + SSP T   T + T  P+   T        T P  TS   TLS
Sbjct: 2182 STTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLS 2241

Query: 1730 PPPSTTTSPPGTPTRG----TTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGL 1785
              P  T++P  T T      TT   +S PT +  + TT     P    L   S + T   
Sbjct: 2242 ATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLST 2301

Query: 1786 RPYPSSVLICCVLNDTYYAPGEE-----VYNGTYGDT-CYFVNCSLSCTLEFYNWSCPST 1839
             P  S+         +   P  E         + G+T    +  S +    F   +  +T
Sbjct: 2302 TPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTT 2361

Query: 1840 PSPTPTP------SKSTPTPSKPSSTPSK-----PTPGTKPP 1870
            P+ T TP      + S+PT +  +S P+       TP T  P
Sbjct: 2362 PADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVP 2403



 Score =  201 bits (510), Expect = 1e-50
 Identities = 247/905 (27%), Positives = 360/905 (39%), Gaps = 171/905 (18%)

Query: 1100 GASVPTEETCK-SCVCTN---SSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFN 1155
            G S+PT  T + S + T+   S+ +V  PE   +L    D         GP  T     N
Sbjct: 1265 GTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTK-------GPVVTS----N 1313

Query: 1156 ICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSST---VLSTTP-----------K 1201
              S +  P+  T+  T T     T  T+    TT  +S+   +LSTTP           +
Sbjct: 1314 EVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTE 1373

Query: 1202 LCCLWSDWINEDHPSSGSDDGDR-------ETFDGVCGAPEDIECRSV--KDPHLSLEQL 1252
             C   +       P+S   +G          T   V      +    V    P  +  + 
Sbjct: 1374 ACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEA 1433

Query: 1253 GQKVQLVCDVSVGLICKNEDQKPGGVIPMAFC--LNYEINVQCCECVTQPTTMTTTTTEN 1310
                     +S+     +E + P   IP++     N E +      V   + + T+T  +
Sbjct: 1434 TSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVS 1493

Query: 1311 PTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1370
             +PTP   T+    TP+  ST  T+    TTT   +   + + T   T+TP+TT +  + 
Sbjct: 1494 SSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASS 1553

Query: 1371 TPT-------PTGTQTPTTTPITT------------TTTVTPTPTPTGTQTPTSTPITTT 1411
            +PT        T T +  +TP+T+              T++ TP  + TQ   ST  +++
Sbjct: 1554 SPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSS 1613

Query: 1412 TT------------------------VTPTPTPTGTQTPTT-----TPITTTTTVTPTPT 1442
            TT                         TP  +P  +   TT     +P+ T+T V+ +PT
Sbjct: 1614 TTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPT 1673

Query: 1443 PT-GTQAPTPT-----AITTTSTVTPTP-----------TPTGTQTPTTT-------PIT 1478
            P  GT  PT T        T+ TV  TP           TP    TP TT       P T
Sbjct: 1674 PAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTT 1733

Query: 1479 TTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTP--TSTPITTTTTVTPTPTPT 1536
            +  T  P  TP+   TP  +   +TT V  +   T + TP  TSTP+TT+T  T +PT  
Sbjct: 1734 SEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTA 1793

Query: 1537 -GTQTPTPTPISTTTTVTPTP------------TPTGTQTPTTTPITTTTTVTPTPTPT- 1582
             GT  PT T     T +T TP            T + T   + +P+ T+T V+ +PTP  
Sbjct: 1794 EGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAE 1853

Query: 1583 GTQTPTTVLITTTTTMTPTPTPTSTKSTTVT-PITTTTTVTATPTPTGTQTPTMIPISTT 1641
            GT   T+     +T +T  P  T+T +++ T  ++TT  VT+TP  T  Q  +  P +  
Sbjct: 1854 GTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSS-PTTAD 1912

Query: 1642 TTVTPTPTPTTGS---TGPPTHTSTAPIAELTT-SNPPPESSTPQT--SRSTSSPLTEST 1695
             +  PT TP  G    T  P  T+T   +E+ T S    ++ TP T  S+++SSP T   
Sbjct: 1913 GSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADG 1972

Query: 1696 TLLSTLPPAIEMTSTAPPSTPTAPT--TTSGGHTLSPPPSTTTSPPGTPTRG----TTTG 1749
            T + T  PA    ST   S P + T   +S   TLS  P  T++P  T T G    TT G
Sbjct: 1973 TSMPT--PAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAG 2030

Query: 1750 SSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEV 1809
             +S  T +  + TT  A  P  T L   S   T    P  S                 +V
Sbjct: 2031 GTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKT---------------QV 2075

Query: 1810 YNGTYGDTCYFVNCSLSCTLEFYNW--SCPSTPSP--TPTPSKSTPTPSKPSSTPSKPTP 1865
             N T          S S T E  +   S PS  SP  T  P  +TP  S  +ST S    
Sbjct: 2076 TNST--------EASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPV 2127

Query: 1866 GTKPP 1870
             +  P
Sbjct: 2128 DSNSP 2132



 Score =  201 bits (510), Expect = 1e-50
 Identities = 216/778 (27%), Positives = 325/778 (41%), Gaps = 78/778 (10%)

Query: 1156 ICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHP 1215
            + SI    +T+ +  T TL TTP   +T  TT    SS+   TT     + +    E  P
Sbjct: 1869 LTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSS--PTTADGSSMPTSTPREGRP 1926

Query: 1216 SSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQKP 1275
               S      T                + P  +  Q           S+     +E   P
Sbjct: 1927 PLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTP 1986

Query: 1276 GGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTT 1335
               +P++  L               T+   TT+   + +P T   T   T TP  ++ TT
Sbjct: 1987 LTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTP--SERTT 2044

Query: 1336 P---TPITTT-------TTVTPTPTPTGTQTPTTTPITTTTT-----VTPTPTPTGTQTP 1380
            P    P++TT        T++ TP  + TQ   +T  +++ T     +T +    G+   
Sbjct: 2045 PLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLL 2104

Query: 1381 TTTPITTTTTVTP-TPTPTGTQTPTSTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVT 1438
            T+ P++TT   +P   T + T   +++P+ T+T V+ +P PT GT   T+T     T +T
Sbjct: 2105 TSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLT 2164

Query: 1439 PTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTT-------TPITTTTTVTPTPTPTG 1491
              P  T   A   +AI+T ST     TP  T TP T       +P T+  T  PT TP+ 
Sbjct: 2165 SMPVSTTVVA--SSAISTLST-----TPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSE 2217

Query: 1492 TQTPTPTAITTTTTVTPTPTPTGTQTP--TSTPITTTTTVTPTPTPT-GTQTPTPTPIST 1548
              TP  +   +T  V  +   T + TP  TSTP+TT+T  T +PT   GT  PT T    
Sbjct: 2218 GSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEG 2277

Query: 1549 TTTVTPTP------------TPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTVLITTT 1595
            TT +T  P            T + T   + TP TT+T   +P PT  GT  PT+      
Sbjct: 2278 TTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGN 2337

Query: 1596 TTMTPTPTPTS-TKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGS 1654
            T +T  P  T+   S   + ++TT   T+TP  T +Q  +  P +   T  PT T + GS
Sbjct: 2338 TPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSS-PTTADDTSMPTSTYSEGS 2396

Query: 1655 TGPPTH--TSTAPIAE---LTTSNPPPESSTPQT--SRSTSSPLTESTTLLSTLPPAIEM 1707
            T P T    ST P+      T S  P ++STP T  + ++SSP T   T + T PP+   
Sbjct: 2397 T-PLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGT 2455

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS---------SSAPTPST 1758
            T  A     T P  +S   TLS  P  T++P  T T  +++ +         S+A   ST
Sbjct: 2456 TPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGST 2515

Query: 1759 VQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTC 1818
            + T+   + TP  +P    S + TT +      V    + +    A G  +   TY +  
Sbjct: 2516 LLTSIPVSTTPVASP--EASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGS 2573

Query: 1819 YFVNCSLSCTLEFYNWSCPSTPSPTPTPSK-----STPTPSKPSSTPSKPTPGTKPPE 1871
              +  S+  + +    S  ST S TP  +      ST T S P++      P + P E
Sbjct: 2574 TPLR-SMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSE 2630



 Score =  199 bits (506), Expect = 3e-50
 Identities = 202/683 (29%), Positives = 308/683 (45%), Gaps = 118/683 (17%)

Query: 1295 ECVTQPTTM------TTTTTENPTPTPITTTTTVTPTPTPTSTQSTTP----TPITTTTT 1344
            E  + PTT       T+T +E  TP   T  +      +  ST STTP    +P+ T+T 
Sbjct: 1785 EATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTA 1844

Query: 1345 VTPTPTPT-GTQTPTTTPI----------TTTTTVTPTPTPTGTQTP--TTTPITTTTTV 1391
            V+ +PTP  GT   T+TP            +TTTV  + T T + TP  T+TP+TT   V
Sbjct: 1845 VSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQV 1904

Query: 1392 TPTPTPT-GTQTPTSTP-----------ITTTTTV-TPTPTPTGTQTPTTTPITTTTTVT 1438
            + +PT   G+  PTSTP           ++TTT   +   T + T   T TP+TT +  +
Sbjct: 1905 SSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQAS 1964

Query: 1439 PTPTPT-GTQAPTP------TAIT----TTSTVTPTPTPTGTQTP--TTTPITTTTTVTP 1485
             +PT   GT  PTP      T +T    +T+ V  +   T + TP  T+TP TT+T  + 
Sbjct: 1965 SSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSS 2024

Query: 1486 TPTPTG---TQTPTPTAITTT----------------TTVTPTPTPTGTQTPTSTPITTT 1526
            +PT  G    QT TP+  TT                  T++ TP  + TQ   ST  +++
Sbjct: 2025 SPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSS 2084

Query: 1527 TT-----VTPTPTPTGTQTPTPTPISTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPT 1580
             T     +T +    G+   T  P+STT   +P   T + T   + +P+ T+T V+ +P 
Sbjct: 2085 ATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPI 2144

Query: 1581 PT-GTQTPTTVLITTTTTMTPTPTPTS-TKSTTVTPITTTTTVTATPTPTGTQTPTMIPI 1638
            PT GT   T+      T +T  P  T+   S+ ++ ++TT   T+TP    T+  +  P 
Sbjct: 2145 PTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSS-PT 2203

Query: 1639 STTTTVTPTPTPTTGS---TGPPTHTSTAPIAELTT-SNPPPESSTPQT--SRSTSSP-- 1690
            ++  T  PT TP+ GS   T  P  T     +E +T S  P ++STP T  + +TSSP  
Sbjct: 2204 TSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTT 2263

Query: 1691 ----------LTESTTLLSTLPPA--------IEMTSTAPPSTPTAPTTTSGGHTLSPPP 1732
                      L+E TT L+++P +        +   ST P  + T  TT++     SPPP
Sbjct: 2264 AEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTST--EASSPPP 2321

Query: 1733 ST--TTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPS 1790
            +   T+ P  T + G T  +    + + V +  TS  + TP   STP  + T        
Sbjct: 2322 TAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTP--VTTYSQAGSSP 2379

Query: 1791 SVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCP---STPSPTPTPS 1847
            +      +  + Y+ G          T   V+   S      + + P   STP  T T +
Sbjct: 2380 TTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEAST-----HSTTPVDTSTPVTTSTEA 2434

Query: 1848 KSTPTPSKPSSTP-SKPTPGTKP 1869
             S+PT ++ +S P S P+ GT P
Sbjct: 2435 SSSPTTAEGTSIPTSPPSEGTTP 2457



 Score =  197 bits (500), Expect = 1e-49
 Identities = 196/637 (30%), Positives = 277/637 (43%), Gaps = 97/637 (15%)

Query: 1298 TQPTTMTTTTTENPTPTPITTTTTVTPTPT------PTSTQSTTPTPIT----TTTTVTP 1347
            ++ +T++TT  ++ TP   T+T   +P PT      PTST S   TP+T    +TT V  
Sbjct: 998  SEASTLSTTPVDSNTPLT-TSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVAS 1056

Query: 1348 TPTPTGTQTP--TTTPITT-------TTTVTPTPTPTGTQTPTTTPITT----TTTVTPT 1394
            + T T + TP  T+TP+TT       +TT   T  PT T +  +TP+T+    T  V  +
Sbjct: 1057 SETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSS 1116

Query: 1395 PTPTGTQTP--TSTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQAPTP 1451
               T + TP  TS P+TT+T  + +PT   GT  PT+ P   TT +   P  T     T 
Sbjct: 1117 EASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVST-----TL 1171

Query: 1452 TAITTTSTVTPTPTPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTPTAITTTTTV 1506
               +  +T++ TP  + TQ  T+T     P T   T  PT TP    TP  +     T V
Sbjct: 1172 VVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPV 1231

Query: 1507 TPTPTPTGTQTP--TSTPITTTTTVTPTPTPT-GTQTPTPT-----------PISTTTTV 1552
              +   T + +P  TSTP+TT+   + +PT   GT  PT T           P+STT   
Sbjct: 1232 ASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVT 1291

Query: 1553 TP-TPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTVLITTTTTMTPTPTPT----- 1605
            +P   T   T   T  P+ T+  V+ +PTP  GT  PT+      T +T  P  T     
Sbjct: 1292 SPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVAS 1351

Query: 1606 ---STKSTT----VTPITTTTTVTATPTPT-GTQTPTMIPISTTTTVTPTPTPTTGSTGP 1657
               S  STT     TP+TT+T   ++PT + GT  P   P   TT +T  P  TT     
Sbjct: 1352 SAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTT----- 1406

Query: 1658 PTHTSTAPIAELTTSNPPPESSTPQT--SRSTSSPLTESTTLLSTLPPAIEMTSTAPPST 1715
            P  +S A     T S  P ++STP T  + +TSSP T     + T  P+   T       
Sbjct: 1407 PVVSSEAS----TLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPV 1462

Query: 1716 PTAPTTTSGGHTLSPPP---------STTTSPPGTPTRGTTTGSSSAPTPSTVQT----T 1762
               P   S   TLS  P         ST  S   TP  GT+   S+    ST  T    +
Sbjct: 1463 SNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVS 1522

Query: 1763 TTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVN 1822
            TT+  +     LST   + +T +  Y  +       +    A G  +   TY +    + 
Sbjct: 1523 TTTVASSEINSLSTTPAVTSTPVTTYSQA------SSSPTTADGTSMQTSTYSEGSTPLT 1576

Query: 1823 CSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSST 1859
             SL  +      S  +T S TP  SK+  T S  +S+
Sbjct: 1577 -SLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASS 1612



 Score =  196 bits (498), Expect = 3e-49
 Identities = 204/675 (30%), Positives = 290/675 (42%), Gaps = 115/675 (17%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPT-------PTSTQSTTPTPITT----TTTV 1345
            V      T +TT   T TP+T +T    +PT       PTST S   TP T+    T  V
Sbjct: 2173 VASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPV 2232

Query: 1346 TPTPTPTGTQTP--TTTPITTTTTVTPTPT-------PTGTQTPTTTPITTT----TTVT 1392
              +   T + TP  T+TP+TT+T  T +PT       PT T +  TTP+T+     T V 
Sbjct: 2233 VTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVA 2292

Query: 1393 PTPTPTGTQTP--TSTPITTTTTVT-PTPTPTGTQTPTTT-----------PITTTTTVT 1438
             +   T + TP  ++TP TT+T  + P PT  GT  PT+T           P++TT   +
Sbjct: 2293 NSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVAS 2352

Query: 1439 -PTPTPTGTQAPTPTAITTTSTVTPTPT-------PTGTQTPTTTPITT----TTTVTPT 1486
              T T + T A T T +TT S    +PT       PT T +  +TP+T+    T  V  +
Sbjct: 2353 FETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSS 2412

Query: 1487 PTPTGTQTP--TPTAITTTTTVTPTPTPT-GTQTPTSTPITTTTTVTPTPTPT------- 1536
               T + TP  T T +TT+T  + +PT   GT  PTS P   TT +   P  T       
Sbjct: 2413 EASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSE 2472

Query: 1537 -GTQTPTP----TPISTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTV 1590
             GT + TP    TP++T+T  + +PT       P +T    +T +T  P  T     T V
Sbjct: 2473 AGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVST-----TPV 2527

Query: 1591 LITTTTTMTPTPTPTSTKSTTVTPITTTTTV---TATPTPTGTQTPT---MIPIST---- 1640
                 +T++ TP  +++   T T I+++ T    T+ PT T ++  T    +P+ST    
Sbjct: 2528 ASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLA 2587

Query: 1641 ---TTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNP---PPESSTPQTS--RSTSSPLT 1692
                +T++ TP  T+      T TS++P     TS P   P E ST  TS   ST    +
Sbjct: 2588 SSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVAS 2647

Query: 1693 ESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRG-----TT 1747
               + LST P       T    T ++PTT  G    S  P++T     TP        T 
Sbjct: 2648 SEASTLSTTPVDTRTLVTTSTGTSSSPTTAEG----SSMPTSTPGERSTPLTNILVSTTL 2703

Query: 1748 TGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLR---PYPSSVLICCVLNDTYYA 1804
              +S A T ST    T++  T +    S+P+    T +R   P   S  +  +L  T   
Sbjct: 2704 LANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPV 2763

Query: 1805 PGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCP----------STPSPTPTPSKSTPTPS 1854
               E    T   T   V+ S+  T      S P          STPS T TP  S P   
Sbjct: 2764 ASSEA--STVSTTA--VDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNH 2819

Query: 1855 KPSSTPSKPTPGTKP 1869
             P ++    T  T P
Sbjct: 2820 TPVASSEAGTLSTTP 2834



 Score =  196 bits (498), Expect = 3e-49
 Identities = 227/816 (27%), Positives = 337/816 (41%), Gaps = 103/816 (12%)

Query: 1156 ICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSST--VLSTTPKLCCLWSDW---- 1209
            + S+    +T+ +  T TL TTP   +T  TT +  SS+  +   T      +S+     
Sbjct: 3283 LTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPL 3342

Query: 1210 INEDHPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICK 1269
             N    ++     +  T       P D           SL     +       S+     
Sbjct: 3343 TNMSFSTTPVVSSEASTLSTT---PVDTSTPVTTSTEASLSPTTAE-----GTSIPTSSP 3394

Query: 1270 NEDQKPGGVIPMAFC--LNYEINVQCCECVTQPTTMTTTTTENPTPTPI------TTTTT 1321
            +E   P   +P++    ++ E+N      V   T +TT+T  + +PT        T+TT+
Sbjct: 3395 SEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTS 3454

Query: 1322 VTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPTPTPTGTQTP 1380
               TP      STTP   +  +T++ TP  T T   T++P  ++ TT   T  PT T   
Sbjct: 3455 EGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGE 3514

Query: 1381 TTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1440
             +TP+T     T     +   T ++TP+ + T VT +     + +P T  +TT    TP+
Sbjct: 3515 GSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQ--ASSSPATLQVTTMRMSTPS 3572

Query: 1441 PTPTG--TQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTP---------TP 1489
               +   T   + T +T++   TP+       TP TT  +T +  TPTP         TP
Sbjct: 3573 EGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTT--STQSNSTPTPPEVITLPMSTP 3630

Query: 1490 TGTQTPTPTAITTTTTVTPTPTPTGTQTP--TSTPITTTTTVTPTP-TPTGTQTPTPTPI 1546
            +   TP      +TT+VT +   T +  P  TSTP+ T+T V+ +P TP GT  P  TP 
Sbjct: 3631 SEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPS 3690

Query: 1547 STTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPT-PTP 1604
              +T +T  P  T   T +  + ++T + VT TP  T T+  ++     +TTM+ + P  
Sbjct: 3691 EGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPME 3750

Query: 1605 TSTKSTTVTPITTTTTVTATP---TPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHT 1661
             ST  TT+  + +TT VT  P   TP+     T + ++T +  + +PT   G+T  P  T
Sbjct: 3751 ISTLGTTI--LVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMST 3808

Query: 1662 STAPIAELTTS-------NPPPESSTPQTSRS-TSSPLTESTTLLSTLPPA----IEMTS 1709
            ++     LTT          P E+ST  T    TS+PL  ST   S   PA    I ++ 
Sbjct: 3809 TSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISI 3868

Query: 1710 TAPPSTP--------TAPTTTSGGHTLSPPP--STTTSPPGTPTRGTTT----------- 1748
            T+  STP        T PT+  G    S PP  ++TT  P T T  T T           
Sbjct: 3869 TSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSV 3928

Query: 1749 ---GSSSAPT---PSTVQTTTTSAWTPTPT-PLSTPSIIRTTGLRPYPSSVLICCVLNDT 1801
               GS+   T   PST  T++T+   P  T  +STP I  T    P  SS       + T
Sbjct: 3929 ITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTT 3988

Query: 1802 YY---------APGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPT 1852
                       AP   V   T   T      S  CT      S  STP  + + +    T
Sbjct: 3989 KEFTTPAMTTAAPLTYVTMSTAPSTPR--TTSRGCTTSASTLSATSTPHTSTSVTTRPVT 4046

Query: 1853 PSKPSSTPSKPT----PGTKPPECPDFDPPRQENET 1884
            PS  SS PS  T    P T PP      P    + T
Sbjct: 4047 PSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASST 4082



 Score =  196 bits (498), Expect = 3e-49
 Identities = 189/690 (27%), Positives = 297/690 (43%), Gaps = 78/690 (11%)

Query: 1155 NICSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINE-- 1212
            +I  ++T P  + +    TL TTP   +T  TT++PT+S+   TT ++  + +    E  
Sbjct: 3461 SIMPLSTTP--VASSEASTLSTTPVDTSTPVTTSSPTNSS--PTTAEVTSMPTSTAGEGS 3516

Query: 1213 ----DHPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLIC 1268
                + P S +     E    +   P D           S      +V  +    +    
Sbjct: 3517 TPLTNMPVSTTPVASSEA-STLSTTPVDSNTFVTSSSQASSSPATLQVTTM---RMSTPS 3572

Query: 1269 KNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTP 1328
            +        ++   +  + E +      V + T +TT+T  N TPTP    T    TP+ 
Sbjct: 3573 EGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSE 3632

Query: 1329 TSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITT 1387
             ST  T     TT+ T++   T +     T+TP+ T+T V+ +P TP GT  P  TP   
Sbjct: 3633 VSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEG 3692

Query: 1388 TTTVTPTPTPTGTQTP------------TSTPITTTT-TVTPTPTPTGTQTPTTTPIT-- 1432
            +T +T  P  T   T             TSTP+TT+T  ++ + T   T    + P+   
Sbjct: 3693 STPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEIS 3752

Query: 1433 ---TTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTT---TTVTPT 1486
               TT  V+ TP     ++ TP+  +  ++++ T    G+ +PTT   TTT   +T +  
Sbjct: 3753 TLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSER 3812

Query: 1487 PTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQT------ 1540
             T   T   +P ++ + +  +   TP G    TSTP+ T+T       P    T      
Sbjct: 3813 STLLTTVLISPISVMSPSEASTLSTPPGD---TSTPLLTSTKAGSFSIPAEVTTIRISIT 3869

Query: 1541 -PTPTPISTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTM 1598
                TP++T    T  PT   G    +T P+ T+TT TP+     T T       + + +
Sbjct: 3870 SERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVI 3929

Query: 1599 TPTPTPTSTKSTTVTPITTTT------TVTATPTPTGTQTPTMIPISTTTTVTPTPTPTT 1652
            T   TP +T     TP+T++T      T  A  TP  T T    P ST+++ T T   TT
Sbjct: 3930 TEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTP-STSSSSTTTSFSTT 3988

Query: 1653 GSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAP 1712
                 P  T+ AP+  +T S  P   STP+T+    +  T ++TL +T  P    + T  
Sbjct: 3989 KEFTTPAMTTAAPLTYVTMSTAP---STPRTTSRGCT--TSASTLSATSTPHTSTSVTTR 4043

Query: 1713 PSTPTAPTT---TSGGHTLSP--PPSTTTSPPGTPTRGTTTGSSSAPT------PSTVQT 1761
            P TP++ ++   T   HT+ P  PP+ +++PP T    TT    +  T      PST  T
Sbjct: 4044 PVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTT 4103

Query: 1762 ---TTTSAWTPTPT-----PLSTPSIIRTT 1783
               T T+   PT T     P STP++ RTT
Sbjct: 4104 SFPTVTTTAVPTNTTIKSNPTSTPTVPRTT 4133



 Score =  194 bits (492), Expect = 1e-48
 Identities = 229/805 (28%), Positives = 326/805 (40%), Gaps = 164/805 (20%)

Query: 1173 TLPTTPTTFTTTTTTTTPTSS---TVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDG 1229
            TL TTP    T  TT+T  SS   T   T+          +    PS GS    R     
Sbjct: 1002 TLSTTPVDSNTPLTTSTEASSPPPTAEGTS----------MPTSTPSEGSTPLTRMPVST 1051

Query: 1230 VCGAPEDIECRSV-----KDPHLSLEQLGQKVQLVCDVSVGLICKNEDQKPGGVIPMAFC 1284
               A  +    S        P  +  Q           S+     +E   P   +P++  
Sbjct: 1052 TMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTR 1111

Query: 1285 LNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPT---PITT 1341
            L               T++  TT+   + +P T   T  PT  P+  + TTP    P++T
Sbjct: 1112 LVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPS--EGTTPLASMPVST 1169

Query: 1342 T-------TTVTPTPTPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTTTPITTTT 1389
            T        T++ TP  + TQ  T+T     P T   T  PT TP    TP T+     T
Sbjct: 1170 TLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHT 1229

Query: 1390 TVTPTPTPTGTQTP--TSTPITTTTTVTPTPTPT-GTQTPTTT-----------PITTTT 1435
             V  +   T + +P  TSTP+TT+   + +PT   GT  PT+T           P++TT 
Sbjct: 1230 PVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTL 1289

Query: 1436 TVTPTP-----TPTGTQAPTPTAITTTSTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 1489
              +P       TP  T+ P    + T++ V+ +PTP  GT  PT+T     T +T  P  
Sbjct: 1290 VTSPEASTLLTTPVDTKGP----VVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVN 1345

Query: 1490 TGTQTPTPTAITTTTTV-TPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTP-TPTPIS 1547
            T     +  +I +TT V   TP  T T+   S+P T+  T  P   P+   TP T  P+S
Sbjct: 1346 TTLVASSAISILSTTPVDNSTPVTTSTEA-CSSPTTSEGTSMPNSNPSEGTTPLTSIPVS 1404

Query: 1548 TTTTV-----TPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTVLITTT 1595
            TT  V     T + TP  T TP TT    T++ T       PT TP+  +TP   +  + 
Sbjct: 1405 TTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSN 1464

Query: 1596 TTM--TPTPTPTSTKSTTVTPITTTTTVTATPTPT------------GTQTPTMIPISTT 1641
            T +  +   T ++T   + +P+ T+T V+++PTP             G+   T IP+STT
Sbjct: 1465 TPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTT 1524

Query: 1642 T---------TVTP--TPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSP 1690
            T         + TP  T TP T  +   +  +TA    + TS    E STP TS   S+ 
Sbjct: 1525 TVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTST-YSEGSTPLTSLPVSTM 1583

Query: 1691 LTEST--TLLSTLP----------PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTT-- 1736
            L  S+    LST P               ++TA  S+ T  T + G   L+  P +TT  
Sbjct: 1584 LVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPV 1643

Query: 1737 SPPGTPTRGTT-----------TGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGL 1785
            + P   T  TT           T  SS+PTP+   +  TS +T   TPL T   +RTT  
Sbjct: 1644 ASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPL-TSITVRTT-- 1700

Query: 1786 RPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPT 1845
             P  SS +                              S   T    N    STP  T T
Sbjct: 1701 -PVASSAI------------------------------STLSTTPVDN----STPVTTST 1725

Query: 1846 PSKSTPTPSKPSSTP-SKPTPGTKP 1869
             ++S+PT S+ +S P S P+ GT P
Sbjct: 1726 EARSSPTTSEGTSMPNSTPSEGTTP 1750



 Score =  193 bits (491), Expect = 2e-48
 Identities = 196/678 (28%), Positives = 285/678 (42%), Gaps = 115/678 (16%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPT-------PTSTQSTTPTPITTTTTVTPTP 1349
            V      T +TT   T  P+ T+T  + +PT       PTST +   TP+T+T   T   
Sbjct: 287  VVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPV 346

Query: 1350 TPTGTQTPTTTPITTTTTVT----PTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPT 1404
              +   T + TP+ T+T VT    P+  PT  +  +    T +   TP T  P  T    
Sbjct: 347  ATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVA 406

Query: 1405 STPITTTTTVT------PTPTPTGTQTPTTTPITTTTTVTP----TPTPTGTQAPTPTAI 1454
            S+  +TT+T+        T     + +PTT   T+  T TP    TP  +   + TP A 
Sbjct: 407  SSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVAS 466

Query: 1455 TTTSTVTPTPTPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPT 1509
            +  S ++ TP  + TQ  T+T     P T      PT TP+   TP  +   +T  V  +
Sbjct: 467  SEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASS 526

Query: 1510 PTPTGTQTP--TSTPITTTTTV-TPTPTPTGTQTPTPTPISTTTTVTPTPTPT------G 1560
               T + TP  TSTP+TT++   + + TP GT  PT TP   +T +T  P  T       
Sbjct: 527  EASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSE 586

Query: 1561 TQTPTTTPITTTTTVTPT---------------PTPTGTQTPTTVLITTTTTMTPTPTPT 1605
              T +TTP  + T VT +               PT T ++  TT+   + +T     +  
Sbjct: 587  ASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEA 646

Query: 1606 STKSTTV----TPITTTTTVTATPT-------PTGTQTP-----TMIPISTT-------- 1641
            ST STT     TP+TT+T  T++ T       PT T T      T +P++TT        
Sbjct: 647  STLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEAS 706

Query: 1642 ---TTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTEST--T 1696
               TT   T TP T ST   +  +TA  A + TS  P E STP TS   S  L  S+  +
Sbjct: 707  TLSTTPVDTSTPVTTSTEASSSPTTADGASMPTST-PSEGSTPLTSMPVSKTLLTSSEAS 765

Query: 1697 LLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTP 1756
             LST P       T       +PTTT G          T+ P  TP+ G+   +S   + 
Sbjct: 766  TLSTTPLDTSTHITTSTEASCSPTTTEG----------TSMPISTPSEGSPLLTSIPVSI 815

Query: 1757 STVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGD 1816
            + V +   S  + TP   ++P +  +T +   P+             A G  +   TY +
Sbjct: 816  TPVTSPEASTLSTTPVDSNSP-VTTSTEVSSSPTP------------AEGTSMPTSTYSE 862

Query: 1817 -----TCYFVNCSLSCTLEFYNWSC----PSTPSPTPTPSKSTPTPSKPSSTP-SKPTPG 1866
                 T   V+ +L  T      S      STP    T ++S+PT S+ +S P S P  G
Sbjct: 863  GRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEG 922

Query: 1867 TKP-PECPDFDPPRQENE 1883
            + P    PD   P   +E
Sbjct: 923  STPLTSMPDSTTPVVSSE 940



 Score =  193 bits (491), Expect = 2e-48
 Identities = 195/645 (30%), Positives = 292/645 (45%), Gaps = 98/645 (15%)

Query: 1301 TTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPT---PITT---------TTTVTPT 1348
            +T+ TT+TE   P+ + TT   T   T T ++ +TP    P++T         TT+  P 
Sbjct: 362  STLVTTSTE---PSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPV 418

Query: 1349 PTPT-------GTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTT--TTVTPTPTP 1397
             + T        + +PTT   T+  T TP+   TP  +   +TTP+ ++  + ++ TP  
Sbjct: 419  DSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVD 478

Query: 1398 TGTQTPTST-----PITTTTTVTPTPTPTGTQTPTTT------PITTTTTVTPTPTPTGT 1446
            + TQ  TST     P T      PT TP+   TP T+      P+ ++   T + TP  T
Sbjct: 479  SKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDT 538

Query: 1447 QAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--------GTQTPTP- 1497
              P  T+   +S+ T   TP GT  PT+TP   +T +T  P  T         T + TP 
Sbjct: 539  STPVTTSSEASSSST---TPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPA 595

Query: 1498 ---TAITTT-------TTVTPTPTPTGTQTPTSTPITT----TTTVTPTPTPTGTQTPTP 1543
               T +TT+       TT   T  PT T +   T IT+    TT V  +   T + TP  
Sbjct: 596  DSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVD 655

Query: 1544 --TPISTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTP 1600
              TP++T+T  T + T   GT  PT+T    +T +T  P  T     T V  +  +T++ 
Sbjct: 656  SNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNT-----TLVASSEASTLST 710

Query: 1601 TPTPTSTKSTTVTPITTTTTVTATPTPT-GTQTPTMIPISTTTTVTPTPTPTTGSTGPPT 1659
            TP  TS      TP+TT+T  +++PT   G   PT  P   +T +T  P   T  T    
Sbjct: 711  TPVDTS------TPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEA 764

Query: 1660 HT-STAPIAELTTSNPPPESS-TPQTSRSTSSPL---TESTTLLSTLPPAI-------EM 1707
             T ST P+   T      E+S +P T+  TS P+   +E + LL+++P +I         
Sbjct: 765  STLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEAS 824

Query: 1708 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTS-PPGTPTRGTTTGSSSAPTPSTVQTTTTSA 1766
            T +  P    +P TTS   + SP P+  TS P  T + G T  +S   + + V T+  S 
Sbjct: 825  TLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAIST 884

Query: 1767 WTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGE-EVYNGTYGDTCYFVNCSL 1825
             + TP   STP +  +T  R  P++     +   T   PGE      +  D+   V  S 
Sbjct: 885  LSTTPVDTSTP-VTNSTEARSSPTTSEGTSMPTST---PGEGSTPLTSMPDSTTPVVSSE 940

Query: 1826 SCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTP-SKPTPGTKP 1869
            + TL        STP  T T + S+PT ++ +S P S P+ GT P
Sbjct: 941  ARTLSATPVD-TSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTP 984



 Score =  193 bits (491), Expect = 2e-48
 Identities = 207/698 (29%), Positives = 293/698 (41%), Gaps = 150/698 (21%)

Query: 1295 ECVTQPTTMTTTTTENPTPTPITTTTT---VTPTPTPTSTQST-TPTPITTTTTVT---- 1346
            E  + PTT   T+    TP+ ++T+ T   V+  P  +S  ST + TP+ T T VT    
Sbjct: 2610 ETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTG 2669

Query: 1347 -------------PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP--TTTPITTTTTV 1391
                         PT TP    TP T  + +TT +  +   T + TP  T+TP+TT+   
Sbjct: 2670 TSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEA 2729

Query: 1392 TPTPTPT-GTQTPTSTPITTTTTVTP------------TPTPTGTQTPTTTPITTTTTVT 1438
            + +PT   GT    STP   +T +T               T + T   T+ P+TT+T  +
Sbjct: 2730 SSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEAS 2789

Query: 1439 PTPT-------PTGTQAPTPTAITTTSTVTPTP-------TPTGTQTPTTTPITTTTTVT 1484
             +PT       PT T + T T + T+  V  TP       T + T   T+TP+TT+T  +
Sbjct: 2790 SSPTTAEVTSMPTSTPSETSTPL-TSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKAS 2848

Query: 1485 PTPTPT-GTQTPTPTAITTTTTVTPTPTPT------------GTQTPTSTPITTTTTVTP 1531
             +PT   G   P  TA   +T +T  P  T             T   TS P+TT+T  + 
Sbjct: 2849 SSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSS 2908

Query: 1532 TPTPT-GTQTPTPTPISTTTTVTP----------------TPTPTGTQTPTTT------- 1567
            +PT   GT  P  TP   +T +T                 + TP  T+TP TT       
Sbjct: 2909 SPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSS 2968

Query: 1568 PITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPT--STKSTTVTPITTTTTVTATP 1625
            P T   T  P  TP   +TP T +  +T  +  +   T   T + T TP+TT+T  +++P
Sbjct: 2969 PTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSP 3028

Query: 1626 TPT-GTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHT-STAPIAELTTSNPP-----PES 1678
            T   GT  P   P   +T +T  P  TT    P   T ST P+     SN P       S
Sbjct: 3029 TTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPV----DSNSPVVTSTEVS 3084

Query: 1679 STPQTSRSTSSPL---TESTTLLSTLP--------PAIEMTSTAPPSTPTAPTTTSGGHT 1727
            S+P  +  TS P+   +E +T L+ +P         AI   ST P  T T  TT++  H+
Sbjct: 3085 SSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHS 3144

Query: 1728 LSPPPSTTTSPPGTPTRGTT-----------------TGSSSAP----TPSTVQTTTTSA 1766
                   T+ P  TP+ G+T                 +  S+ P    TP T  T  TS+
Sbjct: 3145 SPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSS 3204

Query: 1767 WTP--TPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 1824
             T   T  P STPS     G+ P     L    +++T  A  E     T   T    N  
Sbjct: 3205 TTAEGTSIPTSTPS----EGMTP-----LTSVPVSNTPVASSEASILST---TPVDSNTP 3252

Query: 1825 LSCTLEFYNW--SCPSTPSPTPTPSK-STPTPSKPSST 1859
            L+ + E  +   +   T  PT TPS+ STP  S P ST
Sbjct: 3253 LTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVST 3290



 Score =  192 bits (489), Expect = 3e-48
 Identities = 181/621 (29%), Positives = 274/621 (44%), Gaps = 72/621 (11%)

Query: 1296 CVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPT----PITTTTTVTPTPTP 1351
            C T P  MT+  +   + TP  ++T +TPT + T+++ST+ +    P +T  T +PT TP
Sbjct: 85   CSTNPE-MTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPT-TP 142

Query: 1352 TGTQTPTTTP-----ITTTTTVTPTPTPT-------GTQTPTTTPITTTTTVTPTP-TPT 1398
             GT  P +TP      +T   V+  P P+         +   +TP+TT+T  + +P TP 
Sbjct: 143  EGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPE 202

Query: 1399 GTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTS 1458
             T  P ST    +T +T  P  T  +  ++  IT  TT     TP    A   ++ TT  
Sbjct: 203  STTIPKSTNSEGSTPLTSMPAST-MKVASSEAITLLTTPVEISTPVTISAQASSSPTTAE 261

Query: 1459 TVT-PTPTPTGTQTP-TTTPITTTTTV-----TPTPTPTGTQTPTPT---AITTTTTVTP 1508
              +     P+G  TP T  P++    V     T + TP  T  P  T   A ++ TT   
Sbjct: 262  GPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEG 321

Query: 1509 TPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTP 1568
            T  PT T T  STP+T+T   T     +   T + TP+ T+T VT +  P+   T     
Sbjct: 322  TSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEAT 381

Query: 1569 ITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVT-------PITTTTTV 1621
               T+T++   TP      +T+L+ ++   T +  P  +K+   T       P T   T 
Sbjct: 382  SMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTS 441

Query: 1622 TATPTPTGTQTP-TMIPISTT-----------TTVTPTPTPTTGSTGPPTHTSTAPIAEL 1669
             AT TP+   TP T +P+STT           TT   + T  T ST   +   TA +  +
Sbjct: 442  IATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSM 501

Query: 1670 TTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLS 1729
             TS  P E STP TS S S+ +  +++  STL       ST P  T T  TT+S   + S
Sbjct: 502  PTST-PSEGSTPLTSMSVST-MPVASSEASTL-------STTPVDTSTPVTTSSEASSSS 552

Query: 1730 PPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYP 1789
              P  T+ P  TP+ G+T   ++ P  ST    ++ A T + TP  + + + T+      
Sbjct: 553  TTPEGTSIPTSTPSEGSTP-LTNMPV-STRLVVSSEASTTSTTPADSNTFVTTSSEASSS 610

Query: 1790 SSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKS 1849
            S+            A G  +   TY +    +  S+S +      S  ST S TP  S +
Sbjct: 611  STT-----------AEGTSMPTSTYSERGTTIT-SMSVSTTLVASSEASTLSTTPVDSNT 658

Query: 1850 TPTPSKPSSTPSKPTPGTKPP 1870
              T S  +++ S    GT  P
Sbjct: 659  PVTTSTEATSSSTTAEGTSMP 679



 Score =  192 bits (489), Expect = 3e-48
 Identities = 225/837 (26%), Positives = 340/837 (40%), Gaps = 154/837 (18%)

Query: 1156 ICSITTRPSTLTTFTTITLPTTPTTF---TTTTTTTTPTSSTVLSTTPKLCCLWSDWINE 1212
            +  I+T     T  T+I + TTP      +T +TT   ++S V+++T            E
Sbjct: 2504 VVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTST------------E 2551

Query: 1213 DHPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNED 1272
               S+ S +G              +    V    L+  +         D S+ +    E 
Sbjct: 2552 ISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTET 2611

Query: 1273 QKPGGV-----IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTP----TPITTTTTVT 1323
                       +P++       ++      T P   +  +T + TP    T +TT+T  +
Sbjct: 2612 SSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTS 2671

Query: 1324 PTPT-------PTSTQSTTPTPIT----TTTTVTPTPTPTGTQTP--TTTPITTTTTVTP 1370
             +PT       PTST     TP+T    +TT +  +   T + TP  T+TP+TT+   + 
Sbjct: 2672 SSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASS 2731

Query: 1371 TPT-----------PTGTQTPTTTPITTTTTVTPTPTPTGTQTP--TSTPITTTTTVTPT 1417
            +PT           P+   TP T+ + +T  V  +   T + T   TS P+TT+T  + +
Sbjct: 2732 SPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSS 2791

Query: 1418 PTPTG-TQTPTTTPITTTTTVTPTP---TPT-----GTQAPTP----TAITTTSTVTPTP 1464
            PT    T  PT+TP  T+T +T  P   TP      GT + TP    T +TT++  + +P
Sbjct: 2792 PTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSP 2851

Query: 1465 TPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTST-- 1521
            T   G   P +T    +T +T  P  T     TP A +  +T++ TP  T     TST  
Sbjct: 2852 TTAEGIVVPISTASEGSTLLTSIPVST-----TPVASSEASTLSTTPVDTSIPVTTSTEG 2906

Query: 1522 ---PITTTTTVTPTPTPTGTQTP------TPTPISTTTTVTPTPTPTGTQTPTTT----- 1567
               P T   T  P  TP+   TP      +  P++ +   T + TP  T+TP TT     
Sbjct: 2907 SSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEAS 2966

Query: 1568 --PITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPT--STKSTTVTPITTTTTVTA 1623
              P T   T  P  TP   +TP T +  +T  +  +   T   T + T TP+TT+T  ++
Sbjct: 2967 SSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASS 3026

Query: 1624 TPTPT-GTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHT-STAPIAELTTSNPPPESST- 1680
            +PT   GT  P   P   +T +T  P  TT    P   T ST P+     SN P  +ST 
Sbjct: 3027 SPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPV----DSNSPVVTSTE 3082

Query: 1681 ----PQTSRSTSSPLT---ESTTLLSTLP--------PAIEMTSTAPPSTPTAPTTTSGG 1725
                P  +  TS P++   E +T L+ +P         AI   ST P  T T  TT++  
Sbjct: 3083 VSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEA 3142

Query: 1726 HTLSPPPSTTTSPPGTPTRGTT-----------------TGSSSAP----TPSTVQTTTT 1764
            H+       T+ P  TP+ G+T                 +  S+ P    TP T  T  T
Sbjct: 3143 HSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEAT 3202

Query: 1765 SAWTP--TPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVN 1822
            S+ T   T  P STPS     G+ P  S      V N    +    + + T  D+    N
Sbjct: 3203 SSTTAEGTSIPTSTPS----EGMTPLTSVP----VSNTPVASSEASILSTTPVDS----N 3250

Query: 1823 CSLSCTLEFYN-------WSCP-STPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPE 1871
              L+ + E  +        S P STPS   TP  S P  +   ++    T  T P +
Sbjct: 3251 TPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPAD 3307



 Score =  191 bits (485), Expect = 8e-48
 Identities = 194/670 (28%), Positives = 281/670 (41%), Gaps = 147/670 (21%)

Query: 1302 TMTTTTTENPTPTPITT-------TTTVTPTPTPTSTQSTTPTPITT----TTTVTPTPT 1350
            T T +TT   T TP+TT        TT   T  PTST S   TP+T+    T  V  +  
Sbjct: 2355 TSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEA 2414

Query: 1351 PTGTQTP--TTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTG-------- 1399
             T + TP  T+TP+TT+T  + +PT   GT  PT+ P   TT +   P  T         
Sbjct: 2415 STHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAG 2474

Query: 1400 ----TQTPTSTPITTTTTVTPTPTPT------------GTQTPTTTPITTTTTVTP---- 1439
                T   TSTP+TT+T  + +PT              G+   T+ P++TT   +P    
Sbjct: 2475 TLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEAST 2534

Query: 1440 -TPTPTGTQAPTPTAITTTSTVTP---TPTPTGTQTPTTTPI----TTTTTVTPTPTPTG 1491
             + TP  + +P  T+   +S+ T    T  PT T +  +TP+     +T  +  +   T 
Sbjct: 2535 LSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTL 2594

Query: 1492 TQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTT 1551
            + TP  T+I  TT+   + +PT T   TS PI+T + V+ + T     T  P   S  +T
Sbjct: 2595 STTPVDTSIPVTTSTETSSSPT-TAKDTSMPISTPSEVSTSLTSILVST-MPVASSEAST 2652

Query: 1552 VTPTPTPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTTVLITTTT--------TM 1598
            ++ TP  T T   T+T     P T   +  PT TP    TP T ++ +TT        T+
Sbjct: 2653 LSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTL 2712

Query: 1599 TPTPTPTSTKSTTV-----TPITTTTTVTATPTPTGTQTP-TMIPIST-----------T 1641
            + TP  TST  TT      +P T   T     TP+   TP T I +ST           +
Sbjct: 2713 STTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVS 2772

Query: 1642 TTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSR-------STSSPLTES 1694
            TT   T  P T ST   +  +TA +  + TS P  E+STP TS        ++S   T S
Sbjct: 2773 TTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPS-ETSTPLTSMPVNHTPVASSEAGTLS 2831

Query: 1695 TTLLSTLPPAIEMTSTAPPSTPTAP-------TTTSGGHTLSPPPSTTTSPPGTPTRGTT 1747
            TT + T  P    TST   S+PT         +T S G TL      +T+P  +    T 
Sbjct: 2832 TTPVDTSTPVT--TSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTL 2889

Query: 1748 TGSSSAPTPSTVQTTTTSAWTPTPT-------PLSTPSIIRTTGLRPYPSSVLICCVLND 1800
               S+ P  +++  TT++  + +PT       P+STPS + T           +  +L  
Sbjct: 2890 ---STTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTP----------LTSILVS 2936

Query: 1801 TYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTP 1860
            T    G E                             ST S TP  +++  T S  +S+ 
Sbjct: 2937 TVPVAGSEA----------------------------STLSTTPVDTRTPVTTSAEASSS 2968

Query: 1861 SKPTPGTKPP 1870
                 GT  P
Sbjct: 2969 PTTAEGTSMP 2978



 Score =  190 bits (483), Expect = 1e-47
 Identities = 204/696 (29%), Positives = 297/696 (42%), Gaps = 134/696 (19%)

Query: 1297 VTQPTTMTTTTTENPTPT-------PITTTT-----------TVTPTPTP-TSTQSTTP- 1336
            V   T MTT+T  + +PT       PI+T +           + TP  +P  ST STTP 
Sbjct: 2481 VDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPV 2540

Query: 1337 ---TPITTTTTVTPTPTPT-GTQTPTTT----------------PITTTTTVTPTPTPTG 1376
               +P+ T+T ++ + T   GT  PT+T                P+ ++   T + TP  
Sbjct: 2541 DSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVD 2600

Query: 1377 TQTPTTTPITTT---TTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITT 1433
            T  P TT   T+   TT   T  P  T +  ST +T+    T     +   T +TTP+ T
Sbjct: 2601 TSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDT 2660

Query: 1434 TTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 1493
             T VT   T TGT + +PT  T   +  PT TP    TP T  + +TT +  +   T + 
Sbjct: 2661 RTLVT---TSTGTSS-SPT--TAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLST 2714

Query: 1494 TPTPTAITTTTTVTPTPTPTGTQ-------TPT--STPITT----------------TTT 1528
            TP  T+   TT+   + +PT  +       TP+  STP+T+                +TT
Sbjct: 2715 TPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTT 2774

Query: 1529 VTPTPTPTGTQTP-TPTPISTTTTVTPTPTPTGTQTPTT------TPITTTTTVTPTPTP 1581
               T  P  T T  + +P +   T  PT TP+ T TP T      TP+ ++   T + TP
Sbjct: 2775 AVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTP 2834

Query: 1582 TGTQTPTTVLITTTTTMTPTPT-------PTSTKSTTVTPIT----TTTTVTATPTPTGT 1630
              T TP    +TT+T  + +PT       P ST S   T +T    +TT V ++   T +
Sbjct: 2835 VDTSTP----VTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLS 2890

Query: 1631 QTP--TMIPISTTTTVTPTPTPTTGSTGP---PTH---------TSTAPIA---ELTTSN 1673
             TP  T IP++T+T  + +PT   G++ P   P+           ST P+A     T S 
Sbjct: 2891 TTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLST 2950

Query: 1674 PPPESSTPQT--SRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPP 1731
             P ++ TP T  + ++SSP T   T +    P    T     S  T P  +S   TLS  
Sbjct: 2951 TPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRT 3010

Query: 1732 PSTTTSPPGTPTRG----TTTGSSSAP--TPSTVQTTTTS-AWTPTPTPLSTPSIIRTTG 1784
            P+ T++P  T T      TT   +  P  TPS   T  TS   + TP  +   S + TT 
Sbjct: 3011 PADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTP 3070

Query: 1785 LRPYPSSVLICCVLNDTYYAPGEEVYNGTYGD----------TCYFVNCSLSCTLEFYNW 1834
            +      V    V +    A G  +   TY +          +   V  S   TL     
Sbjct: 3071 VDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPV 3130

Query: 1835 SCPSTPSPTPTPSKSTPTPSKPSSTP-SKPTPGTKP 1869
               STP  T T + S+PT S+ +S P S P+ G+ P
Sbjct: 3131 D-TSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTP 3165



 Score =  189 bits (479), Expect = 4e-47
 Identities = 206/793 (25%), Positives = 332/793 (41%), Gaps = 105/793 (13%)

Query: 1156 ICSITTRPSTLTTFTTITLPTTP----TTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWIN 1211
            + SI    + +      TL TTP    T FTT+T  ++P  +   ++ P       +   
Sbjct: 2281 LTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPL 2340

Query: 1212 EDHPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNE 1271
               P S +     ET   +   P D        P  +  Q G       D S+     +E
Sbjct: 2341 TRMPVSTTMVASFET-STLSTTPAD-----TSTPVTTYSQAGSSPTTADDTSMPTSTYSE 2394

Query: 1272 DQKPGGVIPMAFC--LNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTP--- 1326
               P   +P++    ++ E +      V   T +TT+T  + +PT    T+  T  P   
Sbjct: 2395 GSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEG 2454

Query: 1327 -TPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPT-GT 1377
             TP ++   + TP+ ++   T + TP  T TP TT       P T    V P  T + G+
Sbjct: 2455 TTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGS 2514

Query: 1378 QTPTTTPITTTTTVTP-TPTPTGTQTPTSTPITTTTTVTPTPTPT-GTQTPTTT------ 1429
               T+ P++TT   +P   T + T   +++P+ T+T ++ + T   GT  PT+T      
Sbjct: 2515 TLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGST 2574

Query: 1430 ----------PITTTTTVTPTPTPTGTQAPTPTAITTTSTVT-------PTPTPTGTQTP 1472
                      P+ ++   T + TP  T  P  T+  T+S+ T       P  TP+   T 
Sbjct: 2575 PLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTS 2634

Query: 1473 TTTPITTTTTVTPTPTPTGTQTP--TPTAITTTTTVTPTPTPT-GTQTPTSTP------- 1522
             T+ + +T  V  +   T + TP  T T +TT+T  + +PT   G+  PTSTP       
Sbjct: 2635 LTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPL 2694

Query: 1523 ---ITTTTTVTPTPTPTGTQTP--TPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1577
               + +TT +  +   T + TP  T TP++T+   + +PT            T   T   
Sbjct: 2695 TNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPT------------TAEGTSMR 2742

Query: 1578 TPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIP 1637
              TP+   TP T ++ +T  +       S++++TV+     T++  T +   + +PT   
Sbjct: 2743 ISTPSDGSTPLTSILVSTLPV------ASSEASTVSTTAVDTSIPVTTSTEASSSPTTAE 2796

Query: 1638 ISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQT--SRSTSSPLTEST 1695
            +++  T TP+ T T  ++ P  HT  A     T S  P ++STP T  ++++SSP T   
Sbjct: 2797 VTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEG 2856

Query: 1696 TL--LSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRG----TTTG 1749
             +  +ST      + ++ P S  T P  +S   TLS  P  T+ P  T T G    TT  
Sbjct: 2857 IVVPISTASEGSTLLTSIPVS--TTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAE 2914

Query: 1750 SSSAP--TPSTVQTTTTSAWTPT-PTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPG 1806
             +S P  TPS V T  TS    T P   S  S + TT +             +    A G
Sbjct: 2915 GTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEG 2974

Query: 1807 EEVYNGTYGD-----TCYFVNCSLSCTLEFYNWS----CPSTPSPTPTPSKSTPTPSKPS 1857
              +   T G+     T   V+     + E    S      STP  T T + S+PT ++ +
Sbjct: 2975 TSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGT 3034

Query: 1858 STP-SKPTPGTKP 1869
              P S P+ G+ P
Sbjct: 3035 GIPISTPSEGSTP 3047



 Score =  181 bits (460), Expect = 6e-45
 Identities = 163/555 (29%), Positives = 244/555 (43%), Gaps = 66/555 (11%)

Query: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQT 1356
            V   T +T+++  + +P  +  TT    TP+  S+  TT    +T  T +   TP+    
Sbjct: 3542 VDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSV 3601

Query: 1357 PTTTPITTTTTVTPTPTPT-------GTQTPTTTPIT----TTTTVTPTPTPTGTQTP-- 1403
              +TP+TT+T    TPTP         T +  +TP+T    +TT+VT +   T +  P  
Sbjct: 3602 DRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVD 3661

Query: 1404 TSTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT-------GTQAPTPTAIT 1455
            TSTP+ T+T V+ +P TP GT  P  TP   +T +T  P  T       G+   TP+ +T
Sbjct: 3662 TSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVT 3721

Query: 1456 TTSTVTPTPTPTGTQTPTTTPIT-----------TTTTVTPTPTPTGTQTPTPTAITTTT 1504
            +T   T T   + + T  +T ++           TT  V+ TP     ++ TP+  +  T
Sbjct: 3722 STPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYT 3781

Query: 1505 TVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTP 1564
            +++ T    G+ +PT+  +  TTT+  + T   +   T   IS  + ++P+   T +  P
Sbjct: 3782 SMSMTTASEGSSSPTT--LEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPP 3839

Query: 1565 --TTTPITTTTTVTPTPTPTGT-----------QTPTTVLITTTTTMTPTP------TPT 1605
              T+TP+ T+T       P               TP T L+ +TT  T  P      TP 
Sbjct: 3840 GDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPP 3899

Query: 1606 STKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTT-TTVTPTPTPTTGSTGP----PTH 1660
               STT TP T T +    P  T      +   ST  TT+    TP T ST       T 
Sbjct: 3900 LDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTG 3959

Query: 1661 TSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPT 1720
              + P+   T  N P  SS+  T+ S S+    +T  ++T  P   +T +  PST   P 
Sbjct: 3960 AVSTPVITSTELNTPSTSSS-STTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPST---PR 4015

Query: 1721 TTSGGHTLSPPPSTTTSPPGTPTRGTT---TGSSSAPTPSTVQTTTTSAWTPTPTPLSTP 1777
            TTS G T S    + TS P T T  TT   T SS +  PST+ + T     P P   STP
Sbjct: 4016 TTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFP-PAHSSTP 4074

Query: 1778 SIIRTTGLRPYPSSV 1792
                 +     P +V
Sbjct: 4075 PTTSASSTTVNPEAV 4089



 Score =  140 bits (354), Expect = 1e-32
 Identities = 124/412 (30%), Positives = 173/412 (41%), Gaps = 54/412 (13%)

Query: 1295 ECVTQPTTMTTTTTENPTPTPITT---TTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTP 1351
            E ++   T+ +TT     P  I+T   T  V+ TP     +S+TP+  +  T+++ T   
Sbjct: 3730 EAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTAS 3789

Query: 1352 TGTQTPTTTPITTTTTVTPTP-----------TPTGTQTP------------TTTPITTT 1388
             G+ +PTT   TTT  ++ T            +P    +P            T+TP+ T+
Sbjct: 3790 EGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTS 3849

Query: 1389 TTVTPTPTPTGTQT-------PTSTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPT 1440
            T       P    T         STP+TT    T  PT   G    +T P+ T+TT TP+
Sbjct: 3850 TKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPS 3909

Query: 1441 PTPTGTQAPTPTAIT-TTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTA 1499
             T T +    P A T + S +T   TP  T    +TP+T++T      T     TP    
Sbjct: 3910 -TDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPV--- 3965

Query: 1500 ITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPT 1559
            IT+T   TP+ + + T T  ST    TT    T  P    T +  P +  TT     T  
Sbjct: 3966 ITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSA 4025

Query: 1560 GTQTPTTTPITTTTTVTPTPTPTGTQT-PTTVLITTTTTMTP-----TPTPTSTKSTTVT 1613
             T + T+TP T+T+  T   TP+   + P+T+   T     P     TP  TS  STTV 
Sbjct: 4026 STLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVN 4085

Query: 1614 PITTTTTVTAT---------PTPTGTQTPTMIPISTTTTVTPTPTPTTGSTG 1656
            P   TT  T T         PT T T  PT   I +  T TPT   TT   G
Sbjct: 4086 PEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTTCFG 4137



 Score =  123 bits (309), Expect = 2e-27
 Identities = 149/547 (27%), Positives = 225/547 (41%), Gaps = 82/547 (14%)

Query: 1375 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTT 1434
            TG+   T T  T+T  V P    + +  P  T I ++ T             + TP  ++
Sbjct: 61   TGSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVT-------------SDTPGVSS 107

Query: 1435 TTVTPTPTPTGTQAPTPTAI----TTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 1490
            T +TPT + T +++ + +      +T  T +PT TP GT  P +TP   + + T     T
Sbjct: 108  TRMTPTESRTTSESTSDSTTLFPSSTEDTSSPT-TPEGTDVPMSTPSEESISSTMAFVST 166

Query: 1491 GTQTPTPTAITTTTTVTPTPTPTGTQTP-TSTPITTTTTVTPTPTPTGTQTP-TPTPIST 1548
                P+  A T+ T      TP  T T  +S+P T  +T  P  T +   TP T  P ST
Sbjct: 167  AP-LPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPAST 225

Query: 1549 -----TTTVTPTPTPTGTQTPTT-------TPITTTTTVTPTPTPTGTQTPTT------V 1590
                 +  +T   TP    TP T       +P T          P+G  TP T      +
Sbjct: 226  MKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVM 285

Query: 1591 LITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPT-GTQTPTMIPISTTTTVTPTPT 1649
            L+ ++   T + TP +T      P+ T+T  +++PT   GT  PT      +T +T TP 
Sbjct: 286  LVVSSEASTLSTTPAATN----IPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPA 341

Query: 1650 PTTG-STGPPTHTSTAPI---AELTTSNPPPESSTPQTSRSTS---SPLTESTTLLSTLP 1702
             T   +T   +  S  P+     +TTS  P  SS P T+ +TS   S L+E +T L+ +P
Sbjct: 342  STMPVATSEMSTLSITPVDTSTLVTTSTEP--SSLPTTAEATSMLTSTLSEGSTPLTNMP 399

Query: 1703 PA--------IEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAP 1754
             +           TST P  + T  TT S   +       T+    TP+ G+T  +S   
Sbjct: 400  VSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPV 459

Query: 1755 TPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTY 1814
            + + V ++  S  + TP    T     T      P++        +    P      G+ 
Sbjct: 460  STTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTA--------EVNSMPTSTPSEGST 511

Query: 1815 GDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTP-------SKSTPTP---SKPSSTPSK-P 1863
              T   V+     + E    S  +TP  T TP       S S+ TP   S P+STPS+  
Sbjct: 512  PLTSMSVSTMPVASSEASTLS--TTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGS 569

Query: 1864 TPGTKPP 1870
            TP T  P
Sbjct: 570  TPLTNMP 576



 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 89/331 (26%), Positives = 124/331 (37%), Gaps = 75/331 (22%)

Query: 1149 TVEKHFNICSITTRPSTLTTFTTITLPTTPTTFTTTT-TTTTPTSSTVLSTTPKLCCLWS 1207
            T E+   + ++    +  T+F   ++ +TP   T+TT T +T T+ST   T P    +  
Sbjct: 3869 TSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTAST--PTIPVATTISV 3926

Query: 1208 DWINEDH--------PSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLV 1259
              I E          PS+       + F    GA                          
Sbjct: 3927 SVITEGSTPGTTIFIPSTPVTSSTADVFPATTGA-------------------------- 3960

Query: 1260 CDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTT 1319
              VS  +I   E   P                         T+ ++TTT   T    TT 
Sbjct: 3961 --VSTPVITSTELNTPS------------------------TSSSSTTTSFSTTKEFTTP 3994

Query: 1320 TTVTPTPTPTSTQSTTP-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 1378
               T  P    T ST P TP TT+   T   T   T + T+TP T+T+  T   TP+   
Sbjct: 3995 AMTTAAPLTYVTMSTAPSTPRTTSRGCT---TSASTLSATSTPHTSTSVTTRPVTPSSES 4051

Query: 1379 TPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1438
            +  +T   T+ T+ PT  P  + TP   P T+ ++ T  P    T T  T P T TT+  
Sbjct: 4052 SRPST--ITSHTIPPTFPPAHSSTP---PTTSASSTTVNPEAVTTMTTRTKPSTRTTSF- 4105

Query: 1439 PTPTPTGTQAPTPTAITTTSTVTPTPTPTGT 1469
              PT T T  PT T I +  T TPT   T T
Sbjct: 4106 --PTVTTTAVPTNTTIKSNPTSTPTVPRTTT 4134


>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
            sapiens]
          Length = 3003

 Score =  227 bits (578), Expect = 1e-58
 Identities = 219/805 (27%), Positives = 312/805 (38%), Gaps = 133/805 (16%)

Query: 367  VLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQ 426
            V +N + + LP V A+  + R S +   V +     L+V    V  + VT+      Q+ 
Sbjct: 1329 VTVNGVDMKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMC 1387

Query: 427  GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDP-----------C 475
            GLCGN+NG   DDF+  +G        F N+W+        L     P           C
Sbjct: 1388 GLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKC 1447

Query: 476  SLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSS 535
               +E     E +C LL     P   CH  VDP    K C +D C    N   LC+ + +
Sbjct: 1448 PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHA 1507

Query: 536  YARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFA 594
            Y  AC A G  +  WR E  C  +   CP +  +     TC   C +LS A   C +G A
Sbjct: 1508 YVSACQAAGGHVEPWRTETFCPME---CPPNSHYELCADTCSLGCSALS-APPQCQDGCA 1563

Query: 595  PVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV--RQEERCVCRDGRLHCRQ 652
              +GC C D  FL     CVP+ +C CYH G+Y E    V+     ++C C  G      
Sbjct: 1564 --EGCQC-DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAG------ 1614

Query: 653  IRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVC-PDGLMDDG 711
                                        + + CQ          C  G VC P G    G
Sbjct: 1615 ----------------------------KGMVCQ-------EHSCKPGQVCQPSG----G 1635

Query: 712  RGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYIT 771
               CV +  C           G   +    TC  + G+ VC       TC ++G  HY +
Sbjct: 1636 ILSCVTKDPC----------HGVTCRPQ-ETCKEQGGQGVCLPNY-EATCWLWGDPHYHS 1683

Query: 772  FDGKYYDFDGHCSYVAVQDYCGQNSSLG--SFSIITENVPCGTTGVTCSKAIKIFMGRTE 829
            FDG+ +DF G C+YV     C   S+ G   F++ T+N   G   V+  + + +    T 
Sbjct: 1684 FDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTN 1743

Query: 830  LKLEDKHRVVIQRDEGHHVAYTTREV----------GQYLVVESST--------GIIVIW 871
            +         I +DE   V      V          G+  V + ++        G+ V +
Sbjct: 1744 IS--------IHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSY 1795

Query: 872  DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTC 928
            D    V + L  SY G VCGLCGN D   NND    +  +  S   +G SW+     P C
Sbjct: 1796 DWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLC 1855

Query: 929  PDVSTNPEP-CSLNPHRRSWAEKQCSILKSSV---FSICHSKVDPKPFYEACVHDSCSCD 984
             D      P C  +   +      C  L S     F+ CH+ V P+ F++ CV D C   
Sbjct: 1856 WDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCM-- 1913

Query: 985  TGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSF 1043
             GGD +  C A+ASY   C   G  +  WR    C I C   +       HYE CG    
Sbjct: 1914 GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCP 1966

Query: 1044 ETCRTINGIHSNISVSYLEG-CYPRCPKDRPIYEEDLKKCVTADK-CGCYVEDTHYPPGA 1101
             +C +   +    + +  EG C   C  D   +     +CV  +  CGC+   T++  G+
Sbjct: 1967 ASCPSPAPL---TTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGS 2022

Query: 1102 SVPTEETCKS-CVC-TNSSQVVCRP 1124
                + TC   C C      +VC P
Sbjct: 2023 EFWADGTCSQWCRCGPGGGSLVCTP 2047



 Score =  205 bits (522), Expect = 4e-52
 Identities = 181/720 (25%), Positives = 278/720 (38%), Gaps = 144/720 (20%)

Query: 427  GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAE 486
            GLCGN+N    DD K   G       G A   +    C  K      PC+   + +    
Sbjct: 2211 GLCGNYNQDPADDLKAVGGKPAGWQVGGA---QGCGECVSKP--CPSPCTPEQQESFGGP 2265

Query: 487  HWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVM 546
              C ++  T+ P   CH  V PA+Y++ C  D C  Q +   LC A+++Y  AC A G  
Sbjct: 2266 DACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQ 2325

Query: 547  LWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFAPVDGCGCP 602
            L  WR    C      CP    +     +C  +C SLS     +S C E      GC C 
Sbjct: 2326 LGEWRRPDFCPL---QCPAHSHYELCGDSCPVSCPSLSAPEGCESACRE------GCVC- 2375

Query: 603  DHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV---RQEERCVCRDGRLHCRQIRLIGQS 659
            D  F+     CVP+ +C C H G Y   G+V       E RC C  G             
Sbjct: 2376 DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPG------------- 2422

Query: 660  CTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEK 719
                                   ++CQ  AA   H EC          ++DG   C    
Sbjct: 2423 ---------------------GHVTCQEGAACGPHEEC---------RLEDGVQAC---- 2448

Query: 720  ECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDF 779
                      +++G      C  C    G                   HYIT DG+ YD 
Sbjct: 2449 ----------HATG------CGRCLANGGI------------------HYITLDGRVYDL 2474

Query: 780  DGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVV 839
             G CSYV  Q  C        FSI+ E    G       + + + +    + L    +V 
Sbjct: 2475 HGSCSYVLAQ-VCHPKPGDEDFSIVLEKNAAGDL-----QRLLVTVAGQVVSLAQGQQVT 2528

Query: 840  IQRDEGHHVAY--------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCG 891
            +   +G  VA          T E G+ +V++++ G+ +++D    + + +   ++G +CG
Sbjct: 2529 V---DGEAVALPVAVGRVRVTAE-GRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCG 2584

Query: 892  LCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEP-----CSLNPHRRS 946
            LCGNF+   ++DF   +    SS   FG +W+   +         P     C        
Sbjct: 2585 LCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPY 2644

Query: 947  WAEKQCSILKS--SVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECT 1004
             + + C  L++    F+ C + + P  ++  CV+D C+    GD    C ++A+Y   C 
Sbjct: 2645 ESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQ 2702

Query: 1005 KEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEG 1063
              G  V  WRT   CP+ C    P H    HY  C      +C  ++G+ +  +    EG
Sbjct: 2703 AAGVAVKPWRTDSFCPLHC----PAHS---HYSICTRTCQGSCAALSGL-TGCTTRCFEG 2754

Query: 1064 CYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCR 1123
            C   C  DR +  + +  C+    CGC     + P  +S+ T +  + C C++SS + C+
Sbjct: 2755 C--EC-DDRFLLSQGV--CIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 2809



 Score =  180 bits (456), Expect = 2e-44
 Identities = 137/466 (29%), Positives = 206/466 (44%), Gaps = 57/466 (12%)

Query: 697  CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--------CN------T 742
            CV GCVC  G +  G G CV    C C       + G ++  D        CN      T
Sbjct: 776  CVEGCVCLPGFVASG-GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVT 834

Query: 743  C----TCKRGRWVCTQ---AVCH----GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 791
            C    +C  G     Q     C+    GTC   G  HY++FDG+ +DF G C+Y+ V   
Sbjct: 835  CRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS- 893

Query: 792  CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHR-VVIQRDEGHHVAY 850
            CGQN++L +F ++ EN   G+  V+ ++A+++     ++ +  ++   V+  D   ++ +
Sbjct: 894  CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPF 953

Query: 851  TTRE-------VGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 903
               +        G+  VV +  G+ V +D    V  K+  SY   +CGLCGNF+    +D
Sbjct: 954  QAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1013

Query: 904  FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPH---RRSWAEKQCSIL--KSS 958
               R     ++ L FGNSW+E       +T P  C        ++  ++ +C IL     
Sbjct: 1014 LALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKG 1073

Query: 959  VFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDL 1017
             F  CHSK+DP+     CV+D C     G     C A+A+YA  C   GA V  WR+ +L
Sbjct: 1074 PFRECHSKLDPQGAVRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEEL 1131

Query: 1018 CPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEE 1077
            CP+ C    PPH    HYE C      +C  +  +         EGC   C +   +  E
Sbjct: 1132 CPLSC----PPHS---HYEACSYGCPLSCGDL-PVPGGCGSECHEGCV--CDEGFALSGE 1181

Query: 1078 DLKKCVTADKCGCYVEDTHYPPGASVPTEETCKS-CVCTNSSQVVC 1122
                C+    CGC  + T++PPG +      C S C C     V C
Sbjct: 1182 ---SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1224



 Score =  176 bits (447), Expect = 2e-43
 Identities = 173/675 (25%), Positives = 248/675 (36%), Gaps = 105/675 (15%)

Query: 604  HTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLH-CRQIRLIGQSCTA 662
            H+ LD +G         C   G      D +      C      +H  R   L   SC  
Sbjct: 1079 HSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP- 1137

Query: 663  PKIHMDCSNLTALATSKPRALSCQTLAA-GYYHTECVSGCVCPDGLMDDGRGGCVVEKEC 721
            P  H +       A S    LSC  L   G   +EC  GCVC +G    G   C+    C
Sbjct: 1138 PHSHYE-------ACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGES-CLPLASC 1189

Query: 722  PCVHNNDLYSSGAKIKVD--CNT-CTCKRGRWVCTQ--------------------AVCH 758
             CVH    +  G        C++ C C+ G  V  +                    AV  
Sbjct: 1190 GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGS 1249

Query: 759  GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCS 818
             TC   G  HY TFDG+ +DF G C YV  Q  CG    L  F+++ ENV  G   V+ +
Sbjct: 1250 STCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVT 1308

Query: 819  KAIKIFMGRTELKLEDKHRVVIQR--DEGHHVAYTTREV-----GQYLVVESSTGIIVIW 871
            + I + +    L+LE +   V     D    V     ++     G  +V+E+  G+ V +
Sbjct: 1309 RVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY 1368

Query: 872  DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE-APTCPD 930
            D    V + +  +Y   +CGLCGN++    +DF   +     +  +FGNSW+E  P  P 
Sbjct: 1369 DLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC 1428

Query: 931  VSTNPEP-----------CSLNPHRRSWAEKQCSILKSSV--FSICHSKVDPKPFYEACV 977
            +   P P           C     ++   E+ C +L S     S CH  VDP+   + C+
Sbjct: 1429 LPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCI 1488

Query: 978  HDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYE 1036
             D C    GG+    CS + +Y   C   G  V  WRT   CP+ C    PP+    HYE
Sbjct: 1489 FDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC----PPNS---HYE 1539

Query: 1037 PCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTH 1096
             C +     C  ++           +GC   C  D        + CV   +CGCY    +
Sbjct: 1540 LCADTCSLGCSALSA-----PPQCQDGCAEGCQCDSGFLYNG-QACVPIQQCGCYHNGVY 1593

Query: 1097 YPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNI 1156
            Y P  +V  +   + C C     +VC+    K             ++C P+G +     +
Sbjct: 1594 YEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCK-----------PGQVCQPSGGI-----L 1637

Query: 1157 CSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPS 1216
              +T  P    T                T          L      C LW D      P 
Sbjct: 1638 SCVTKDPCHGVTCR-----------PQETCKEQGGQGVCLPNYEATCWLWGD------PH 1680

Query: 1217 SGSDDGDRETFDGVC 1231
              S DG +  F G C
Sbjct: 1681 YHSFDGRKFDFQGTC 1695



 Score =  160 bits (404), Expect = 2e-38
 Identities = 118/404 (29%), Positives = 178/404 (44%), Gaps = 39/404 (9%)

Query: 743  CTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFS 802
            C    G+  C  A     C   G  HY TFDG+ YD  G CSY  V+  C ++ +L +FS
Sbjct: 455  CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFS 512

Query: 803  IITENVPCGTTGVTC---------SKAIKIFMGRTELKLED--KHRVVIQRDEGHHVAYT 851
            +  +N   G+  V+          S ++ +  G     L D  + R+ +   EG    Y 
Sbjct: 513  VEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572

Query: 852  TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMV 911
            +   G   VVE   G++V +D    + + L   ++  VCGLCGN++    +DF T D  +
Sbjct: 573  S---GPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGAL 629

Query: 912  VSSELDFGNSWKEAP---TCPDVSTNPEP-CSLNPHRRSWAEKQCSILK--SSVFSICHS 965
                ++F +SWK       C D   N  P C+    +    ++ C +L      F++CH 
Sbjct: 630  APDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 689

Query: 966  KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDY 1024
             +DP+PF E CV+D C    GG+    C  +++YAQ C + G  V  WR+P  CP+ C  
Sbjct: 690  TLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC-- 745

Query: 1025 YNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVT 1084
                      YE CG     +C       +      +EGC   C    P +      CV 
Sbjct: 746  -----PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCV--C---LPGFVASGGACVP 795

Query: 1085 ADKCGCYVEDTHYPPGASVPTEETC-KSCVCTNSS-QVVCRPEE 1126
            A  CGC  +     PG  V  +E C + C C  ++ QV CR ++
Sbjct: 796  ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ 839



 Score =  139 bits (350), Expect = 4e-32
 Identities = 121/485 (24%), Positives = 192/485 (39%), Gaps = 78/485 (16%)

Query: 697  CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCT--CK----RGRW 750
            CV GC C  G +        +   C C  N   + +G++   D  TC+  C+     G  
Sbjct: 1985 CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWAD-GTCSQWCRCGPGGGSL 2043

Query: 751  VCTQAVC-------------HGT-------CSIYGSGHYITFDGKYYDFDGHCSYVAVQD 790
            VCT A C             HG        C  +G  HY+T DG  +DF G C Y+    
Sbjct: 2044 VCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 2103

Query: 791  YCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAY 850
              G      +F++   N   G+  V+ ++++ + +    L L  +    +Q D G  VA 
Sbjct: 2104 CHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD-GVFVAL 2162

Query: 851  T--------TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNN 902
                         G  +VV +++G+ + +D  + V +++  +Y  ++CGLCGN++    +
Sbjct: 2163 PFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPAD 2222

Query: 903  DFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSS--VF 960
            D           ++       E  + P     P PC+            C ++ ++    
Sbjct: 2223 DLKAVGGKPAGWQVGGAQGCGECVSKP----CPSPCTPEQQESFGGPDACGVISATDGPL 2278

Query: 961  SICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCP 1019
            + CH  V P  +++ C+ D+C     G     C AVA+Y   C   GA +  WR PD CP
Sbjct: 2279 APCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCP 2336

Query: 1020 IFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDL 1079
            + C    P H    HYE CG+    +C          S+S  EGC   C ++  + +   
Sbjct: 2337 LQC----PAHS---HYELCGDSCPVSCP---------SLSAPEGCESAC-REGCVCDAGF 2379

Query: 1080 ----KKCVTADKCGCYVEDTHYPPG-ASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQ 1134
                  CV   +CGC  +  +YP G    P  E  + C C     V C           Q
Sbjct: 2380 VLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC-----------Q 2428

Query: 1135 DGAFC 1139
            +GA C
Sbjct: 2429 EGAAC 2433



 Score =  138 bits (348), Expect = 6e-32
 Identities = 126/429 (29%), Positives = 188/429 (43%), Gaps = 37/429 (8%)

Query: 1916 CSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--P 1973
            C+ G +   V    GC    E    C   GDPHY TFDG  Y   G C+Y +VE  S   
Sbjct: 449  CAAGQRCQVVGGKAGCVA--ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDD 506

Query: 1974 SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPY 2033
            ++  F V   N H   + +VS    + VR  +  V +    +  + V  Q +R  V+L  
Sbjct: 507  TLPAFSVEAKNEH-RGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSE 565

Query: 2034 KKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNTKGQCGTCTNTTSDD 2092
             +  L VYQSG   VV++   G++V+Y+     ++ LP  RF +   G CG      +DD
Sbjct: 566  GR--LRVYQSGPRAVVEL-VFGLVVTYDWDCQLALSLP-ARFQDQVCGLCGNYNGDPADD 621

Query: 2093 CILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL 2152
             + P G +  +    A  W ++D    +          PA T PG  +   H +     L
Sbjct: 622  FLTPDGALAPDAVEFASSWKLDDGD--YLCEDGCQNNCPACT-PGQAQ---HYE--GDRL 673

Query: 2153 CQLIK--DSLFAQCHALVPPQHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQNICL- 2208
            C ++   D  FA CH  + P+ + + CV+D C + G  L  C  L AYA  C +  I + 
Sbjct: 674  CGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVG 733

Query: 2209 DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN--NTVLVEGCFCPEGTMNYAP 2266
            DWR+  +  C + CP++  Y+ CGPA   +C  +++  N      VEGC C  G +  + 
Sbjct: 734  DWRSPAN--CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFV-ASG 790

Query: 2267 GFDVCVKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPK-------RCS-Q 2316
            G  V   +CGC   G    P +     E   + C C      + C+ K       RCS Q
Sbjct: 791  GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850

Query: 2317 KPVTHCVED 2325
              +  C  D
Sbjct: 851  NGLLGCYPD 859



 Score =  135 bits (339), Expect = 7e-31
 Identities = 127/510 (24%), Positives = 194/510 (38%), Gaps = 114/510 (22%)

Query: 413  LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSS---CHDKLD 469
            L +++    +G++ GLCGNFNG   DDF   +G   ++   F   W+A  S   C +   
Sbjct: 2570 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 2629

Query: 470  WLDDPCSLNIESANY-AEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDC 528
                P  L  E+A Y +   C  L+  + PF  C + + P+EY+++C YD C  + ++  
Sbjct: 2630 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAF 2689

Query: 529  LCAALSSYARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADS 587
            LC +L++Y  AC A GV +  WR +  C      CP    +     TCQ +C +LS    
Sbjct: 2690 LCRSLAAYTAACQAAGVAVKPWRTDSFCPL---HCPAHSHYSICTRTCQGSCAALSGLTG 2746

Query: 588  HCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE--ERCVCRD 645
                 F   +GC C D  FL  +G C+P+  C C H G YL     ++  +  ERC C  
Sbjct: 2747 CTTRCF---EGCECDDR-FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSC-- 2800

Query: 646  GRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPD 705
                                            S    L+CQ  AAG     C  G VC  
Sbjct: 2801 --------------------------------SSSSGLTCQ--AAG-----CPPGRVC-- 2819

Query: 706  GLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYG 765
                                         ++K +   C   RG  +C  +V     +  G
Sbjct: 2820 -----------------------------EVKAEARNCWATRG--LCVLSVGANLTTFDG 2848

Query: 766  SGHYITFDGKYYDFDGHC----------SYVAVQDYC-GQNSSLGSFSIITENVPCGTTG 814
            +    T  G  Y+    C            VA    C G+  ++G   I  ++   G   
Sbjct: 2849 ARGATTSPG-VYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQD---GMVT 2904

Query: 815  VTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKR 874
            +T +K + +   R +L  E    V + R                L+V    G+ V     
Sbjct: 2905 LTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGS-----------LLVRQKAGVQVWLGAN 2953

Query: 875  TTVFIKLAPSYKGTVCGLCGNFDHRSNNDF 904
              V + ++  + G +CG CGNFD    ND+
Sbjct: 2954 GKVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983



 Score =  129 bits (323), Expect = 5e-29
 Identities = 124/453 (27%), Positives = 171/453 (37%), Gaps = 58/453 (12%)

Query: 1912 PMPTCSN-GLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 1970
            P  TC   G Q V + + +  CW W         GDPHY +FDG  + +QG C YVL   
Sbjct: 1652 PQETCKEQGGQGVCLPNYEATCWLW---------GDPHYHSFDGRKFDFQGTCNYVLATT 1702

Query: 1971 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQ---VQVQVNRQ 2027
              P V   G+         N     P    VR  T   L   + +   +   V+V VN  
Sbjct: 1703 GCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGV 1761

Query: 2028 AVALPYK-KYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCG 2083
              ALP     G      G +  + + + G+ VSY+      V LP  YH       G CG
Sbjct: 1762 LTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH---GAVCGLCG 1818

Query: 2084 TCTNTTSDDCILPSGEIVSNCEAAADQW-------LVNDPSKPHCPHSSSTTKRPAVTVP 2136
                  ++D + P+G +  +       W       L  D  +  CP   +  +       
Sbjct: 1819 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP---TCPEDRLEQYE 1875

Query: 2137 GGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQ 2195
            G G   P    T  P         F  CHA VPP+ ++  CV D C   G   + C +L 
Sbjct: 1876 GPGFCGPLASGTGGP---------FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALA 1926

Query: 2196 AYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV---- 2250
            +Y A C    + + DWR      C + CP +  Y+ CGP    +C S +      V    
Sbjct: 1927 SYVAACQAAGVVIEDWRAQV--GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGP 1984

Query: 2251 LVEGCFCPEGTMNYAPGFDVCV---KTCGCVGPDNVPREFGEHFEFD--CKN-CVCLEGG 2304
             VEGC C  G   +    D CV     CGC   +    E G  F  D  C   C C  GG
Sbjct: 1985 CVEGCQCDAG---FVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGG 2040

Query: 2305 SGIICQPKRCSQKPVTHCVEDGTYLATEVNPAD 2337
              ++C P  C    V   +  G +    V+ A+
Sbjct: 2041 GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAE 2073



 Score =  128 bits (322), Expect = 7e-29
 Identities = 127/447 (28%), Positives = 178/447 (39%), Gaps = 51/447 (11%)

Query: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--PSVDNFGVYIDNYHCDPNDKVSCPRT 1998
            C   GDPHY TFDG  + + G C YVL +     P +  F V  +N     N +VS  R 
Sbjct: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRV 1310

Query: 1999 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGV 2056
            +     T +V   T+ +   Q +V VN   + LP       +   Q G + V++  + G+
Sbjct: 1311 I-----TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGL 1364

Query: 2057 LVSYNGLSFSVRLPYHRFGNNTKGQCGTCTN---TTSDDCILPSGEIVSNCEAAADQWLV 2113
             V+Y+ L + VR+     GN  +  CG C N      DD   P+G    N     + W  
Sbjct: 1365 RVAYD-LVYYVRVTVP--GNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEE 1421

Query: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--------SPLCQLIKDSL--FAQ 2163
              P  P  P        P    PG     P   C P           C L+       + 
Sbjct: 1422 VVPDSPCLP--------PTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 1473

Query: 2164 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALC-AQQNICLDWRNHTHGACLVE 2221
            CH LV PQ     C+FD C   G+ S+ C+++ AY + C A       WR  T   C +E
Sbjct: 1474 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETF--CPME 1531

Query: 2222 CPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 2280
            CP +  Y+ C       C + S+  Q      EGC C  G + Y     V ++ CGC   
Sbjct: 1532 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFL-YNGQACVPIQQCGCY-H 1589

Query: 2281 DNVPREFGEHFEFD-CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 2339
            + V  E  +    D C+       G G++CQ   C  KP   C   G  L+      D C
Sbjct: 1590 NGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSC--KPGQVCQPSGGILSCVTK--DPC 1645

Query: 2340 CNITVCKCNTSLCKEK--PSVCPLGFE 2364
              +T     T  CKE+    VC   +E
Sbjct: 1646 HGVTCRPQET--CKEQGGQGVCLPNYE 1670



 Score =  126 bits (317), Expect = 2e-28
 Identities = 92/266 (34%), Positives = 123/266 (46%), Gaps = 31/266 (11%)

Query: 412 QLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWL 471
           QL ++L    Q QV GLCGN+NG   DDF T  G +      FA++WK      D  D+L
Sbjct: 594 QLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKL-----DDGDYL 648

Query: 472 -DDPCSLNIESAN--YAEHW-----CSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQ 523
            +D C  N  +     A+H+     C +L K + PF  CH  +DP  + ++C YD C   
Sbjct: 649 CEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVG 708

Query: 524 NNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTCRSL 582
                LC  LS+YA+AC   G+ +  WR    C     SCP +  +      C  +C   
Sbjct: 709 GERLSLCRGLSAYAQACLELGISVGDWRSPANCPL---SCPANSRYELCGPACPTSCNG- 764

Query: 583 SEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE---E 639
           + A S+C  G   V+GC C    F+   G CVP + C C  +GL L  G  V   E    
Sbjct: 765 AAAPSNC-SGRPCVEGCVCLP-GFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQR 822

Query: 640 RCVCRDGRLH---CRQIRLIGQSCTA 662
           RC C +G  H   CR      QSC A
Sbjct: 823 RCTC-NGATHQVTCRD----KQSCPA 843



 Score =  125 bits (314), Expect = 6e-28
 Identities = 113/425 (26%), Positives = 166/425 (39%), Gaps = 42/425 (9%)

Query: 1905 KVECEPPPMPTCSNGL-----QPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSY 1959
            + EC P    TC  G      +  R+ED    C    C   C   G  HY+T DG  Y  
Sbjct: 2416 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDL 2474

Query: 1960 QGNCTYVLVE--EISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMP 2017
             G+C+YVL +     P  ++F + ++      N      R L+        +   V  + 
Sbjct: 2475 HGSCSYVLAQVCHPKPGDEDFSIVLEK-----NAAGDLQRLLV-------TVAGQVVSLA 2522

Query: 2018 MQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNG---LSFSVRLPYHRF 2074
               QV V+ +AVALP     + V   G N V+   + G+ + ++G   L  S+  P   F
Sbjct: 2523 QGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTK-GLRLLFDGDAHLLMSIPSP---F 2578

Query: 2075 GNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVT 2134
                 G CG      SDD +LP+G   S+ E     W     SK  C         P   
Sbjct: 2579 RGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCGEGCGPQGCPVCL 2637

Query: 2135 VPGGGKTTPHKDCTPSPLCQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPG-SSLEC 2191
                 +T P++    +  C  +++    FA C A++ P  Y+  CV+D C   G  +  C
Sbjct: 2638 AE---ETAPYES---NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 2691

Query: 2192 ASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NT 2249
             SL AY A C    + +  WR  T   C + CP+H  Y  C    + +C + S      T
Sbjct: 2692 RSLAAYTAACQAAGVAVKPWR--TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT 2749

Query: 2250 VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIIC 2309
               EGC C +  +  + G  + V+ CGC                DC         SG+ C
Sbjct: 2750 RCFEGCECDDRFL-LSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTC 2808

Query: 2310 QPKRC 2314
            Q   C
Sbjct: 2809 QAAGC 2813



 Score =  119 bits (297), Expect = 5e-26
 Identities = 121/456 (26%), Positives = 178/456 (39%), Gaps = 59/456 (12%)

Query: 1915 TCSNGLQPVRVEDPDGCCWHWECD-------CY------CTGWGDPHYVTFDGLYYSYQG 1961
            TC+     V   D   C     C        CY      C G GDPHYV+FDG  + + G
Sbjct: 825  TCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMG 884

Query: 1962 NCTYVLVEEI--SPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQ 2019
             CTY+LV     + ++  F V ++N H       +   T  VR E + V +      P Q
Sbjct: 885  TCTYLLVGSCGQNAALPAFRVLVENEH---RGSQTVSYTRAVRVEARGVKVAVRREYPGQ 941

Query: 2020 VQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNT 2078
            V V    Q +        ++V++ G + VV   + G+ V+Y+     + ++P   +    
Sbjct: 942  VLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVP-SSYAEAL 999

Query: 2079 KGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGG 2138
             G CG      +DD  L  G   +N  A  + W   + ++P C            T PG 
Sbjct: 1000 CGLCGNFNGDPADDLALRGGGQAANALAFGNSW--QEETRPGC----------GATEPG- 1046

Query: 2139 GKTTPHKDCTPSPL------CQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPGSSLE 2190
                P  D   +        C ++ D    F +CH+ + PQ     CV+D C +PG S  
Sbjct: 1047 --DCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGP 1104

Query: 2191 -CASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN- 2247
             C +L  YAA C      +  WR+     C + CP H  Y+AC      +C         
Sbjct: 1105 LCDALATYAAACQAAGATVHPWRSEE--LCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC 1162

Query: 2248 NTVLVEGCFCPEGTMNYAPGFDVC--VKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEG 2303
             +   EGC C EG   +A   + C  + +CGCV  G  + P +           C C EG
Sbjct: 1163 GSECHEGCVCDEG---FALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEG 1219

Query: 2304 GSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 2339
            G  + C+   C   P   C   G  L      + TC
Sbjct: 1220 GL-VSCESSSCG--PHEACQPSGGSLGCVAVGSSTC 1252



 Score =  117 bits (294), Expect = 1e-25
 Identities = 119/428 (27%), Positives = 183/428 (42%), Gaps = 56/428 (13%)

Query: 1913 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 1972
            +P+  +G QPV   +             C  WGDPHYVT DG  + +QG C Y+L     
Sbjct: 2059 LPSGQHGCQPVSTAE-------------CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCH 2105

Query: 1973 P---SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAV 2029
                  +NF V + N H   +  VS  R++ ++     + +          ++QV+   V
Sbjct: 2106 GPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQIYNHSLTLSA----RWPRKLQVDGVFV 2160

Query: 2030 ALPYKKYG-LEVYQSGINYVVDIPELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTN 2087
            ALP++    L  + SG + VV     G+ ++++G SF  +R+P   +  +  G CG    
Sbjct: 2161 ALPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLRVP-AAYAASLCGLCGNYNQ 2218

Query: 2088 TTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDC 2147
              +DD     G+  +  +    Q      SKP CP   +  ++ +    GG         
Sbjct: 2219 DPADDLKAVGGK-PAGWQVGGAQGCGECVSKP-CPSPCTPEQQESF---GGPDACGVISA 2273

Query: 2148 TPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNI 2206
            T  PL         A CH LVPP  Y+  C+ D+C + G     C ++  Y A C     
Sbjct: 2274 TDGPL---------APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGA 2324

Query: 2207 CL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTMNY 2264
             L +WR      C ++CP+H  Y+ CG +   +C S S+ +   +   EGC C  G   +
Sbjct: 2325 QLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG---F 2379

Query: 2265 APGFDVCVKT--CGCVGPDNVPREFGEHF--EFDC-KNCVCLEGGSGIICQPKRCSQKPV 2319
                D CV    CGC+  D      GE F    +C + C C  GG  + CQ +  +  P 
Sbjct: 2380 VLSGDTCVPVGQCGCL-HDGRYYPLGEVFYPGPECERRCECGPGGH-VTCQ-EGAACGPH 2436

Query: 2320 THC-VEDG 2326
              C +EDG
Sbjct: 2437 EECRLEDG 2444



 Score =  107 bits (266), Expect = 2e-22
 Identities = 89/352 (25%), Positives = 139/352 (39%), Gaps = 34/352 (9%)

Query: 12  CLALSLAGGSELQTEGRTRN---HGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCR 68
           C  +  A G   Q  G           VC   G+ HY TFDG  +   G C Y     C 
Sbjct: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 503

Query: 69  --GSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGL 126
              +   F+V  K     +   + V  + +     ++ LTR         V   +    L
Sbjct: 504 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEV----GFVLVDNQRSRL 559

Query: 127 LIEKSDAYTKVYSRA---------GLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQS 177
            +  S+   +VY            GL + ++ +  L L L  +F++  CGLCG+YNG  +
Sbjct: 560 PVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA 619

Query: 178 YSEFLSDGVLF-SPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAE-------CERLL 229
                 DG L    +EF +  K++  D +CED  +   PA C+  +A+       C  L 
Sbjct: 620 DDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLT 678

Query: 230 TAEA-FADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTA 288
             +  FA C D +   P+L  C  D C   G    +C  ++ +++ C   G   G+WR+ 
Sbjct: 679 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 738

Query: 289 TSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHR-MDGCFCPEG 339
            +        +CP N  Y   G  C  +C+     S C     ++GC C  G
Sbjct: 739 AN-----CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG 785



 Score =  104 bits (259), Expect = 1e-21
 Identities = 84/319 (26%), Positives = 129/319 (40%), Gaps = 30/319 (9%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAGVES 93
            C  WG+ HY T DG  F F G C+Y  ++ C G     + F V +      ++A +   S
Sbjct: 2074 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 2133

Query: 94   ILLTIKDDTIYLT----RHLAVLNGAVVSTPHYSPGLL-IEKSDAYTKVYSRAGLTLMWN 148
            + L I + ++ L+    R L V +G  V+ P     LL    S A   V + +GL+L ++
Sbjct: 2134 VTLQIYNHSLTLSARWPRKLQV-DGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 2192

Query: 149  REDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED 208
             +  + L +   +    CGLCG+YN      +  + G   +  + G  Q        C +
Sbjct: 2193 GDSFVRLRVPAAYAASLCGLCGNYNQ-DPADDLKAVGGKPAGWQVGGAQG-------CGE 2244

Query: 209  PEEEVAPASCSEHRAE-------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGG 260
               +  P+ C+  + E       C  +   +   A C  LVP   Y + C  D C+  G 
Sbjct: 2245 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2304

Query: 261  DTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHL 320
               +C  VA +   C  AG + G WR             CP +  Y   G  C  +C  L
Sbjct: 2305 PGGLCPAVATYVAACQAAGAQLGEWRRPDF-----CPLQCPAHSHYELCGDSCPVSCPSL 2359

Query: 321  EVSSLCEEHRMDGCFCPEG 339
                 CE    +GC C  G
Sbjct: 2360 SAPEGCESACREGCVCDAG 2378



 Score =  102 bits (254), Expect = 5e-21
 Identities = 75/235 (31%), Positives = 97/235 (41%), Gaps = 27/235 (11%)

Query: 427  GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS--SCH----DKLDWLDDPCSLNIE 480
            GLCGNFNG   DD     G   A    F N+W+ ++   C          LD   +  ++
Sbjct: 1001 GLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQ 1060

Query: 481  SANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARAC 540
            S N     C +L   + PF  CHS +DP    + C YD C        LC AL++YA AC
Sbjct: 1061 SKNE----CGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAAC 1116

Query: 541  TAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSL---SEADSHCLEGFAPV 596
             A G  +  WR E +C     SCP    +      C  +C  L       S C E     
Sbjct: 1117 QAAGATVHPWRSEELCPL---SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHE----- 1168

Query: 597  DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQ---EERCVCRDGRL 648
             GC C D  F      C+PLA C C H+G Y   G         +  C C++G L
Sbjct: 1169 -GCVC-DEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGL 1221



 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 108/394 (27%), Positives = 156/394 (39%), Gaps = 41/394 (10%)

Query: 348  VVLLADKKKNVVVFKSDGS---VLLNELQVNLPHVTAS--FSVFRPSSYHIMVSMAIGVR 402
            VV +A    N+ + K +     V +N +   LP   A    SV + +S  ++V+      
Sbjct: 1734 VVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVA---DFG 1790

Query: 403  LQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS 462
            LQV      ++ VTL  +  G V GLCGN +    +D    +G +  +   +  +W+A  
Sbjct: 1791 LQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG 1850

Query: 463  ---SCHDKLDWLDDPCSLNIESANYAEHWCS-LLKKTETPFGRCHSAVDPAEYYKRCKYD 518
                C D+       C  +         +C  L   T  PF  CH+ V P  ++K C  D
Sbjct: 1851 WDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLD 1910

Query: 519  TCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQ 577
             C    + D LC AL+SY  AC A GV++  WR  V C     +CP +  +      C  
Sbjct: 1911 VCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI---TCPENSHYEVCGPPCPA 1967

Query: 578  TCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK-CSCYHRGLYLEAG----- 631
            +C S +   +  +     V+GC C D  F+    RCVPL   C C+  G Y EAG     
Sbjct: 1968 SCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWA 2026

Query: 632  DVVVRQEERCVCRDGRLHCRQIRL-IGQSC-TAPKIHMDCSNLTALATSKPRALSCQTLA 689
            D    Q  RC    G L C      +G+ C   P     C  ++           CQ   
Sbjct: 2027 DGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS--------TAECQAWG 2078

Query: 690  AGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPC 723
              +Y        V  DG   D +G C      PC
Sbjct: 2079 DPHY--------VTLDGHRFDFQGTCEYLLSAPC 2104



 Score = 98.2 bits (243), Expect = 9e-20
 Identities = 80/317 (25%), Positives = 134/317 (42%), Gaps = 28/317 (8%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVESI 94
            C   G  HY T DG V+   G C Y  A  C  +   ++F++ L++      A   ++ +
Sbjct: 2456 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKN-----AAGDLQRL 2510

Query: 95   LLTIKDDTIYLTRHLAV-LNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDAL 153
            L+T+    + L +   V ++G  V+ P     + +        + +  GL L+++ +  L
Sbjct: 2511 LVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHL 2570

Query: 154  MLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVVCED---P 209
            ++ + + FR   CGLCG++NG  S    L +G   S +E FG   +       C +   P
Sbjct: 2571 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGP 2630

Query: 210  E-------EEVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGGD 261
            +       EE AP   +E    C +L   +  FA CQ ++    Y R C  D C   G  
Sbjct: 2631 QGCPVCLAEETAPYESNE---ACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 2687

Query: 262  TCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLE 321
              +C ++A ++  C  AG     WRT +          CP +  Y      C  +C+ L 
Sbjct: 2688 AFLCRSLAAYTAACQAAGVAVKPWRTDSF-----CPLHCPAHSHYSICTRTCQGSCAALS 2742

Query: 322  VSSLCEEHRMDGCFCPE 338
              + C     +GC C +
Sbjct: 2743 GLTGCTTRCFEGCECDD 2759



 Score = 86.7 bits (213), Expect = 3e-16
 Identities = 86/330 (26%), Positives = 128/330 (38%), Gaps = 35/330 (10%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFA-SDCRG----SYKEFAVHLKRGPGQAEAPAGV 91
            C  WG+ HY +FDG  F F G C+Y  A + C G        F V  K       A + V
Sbjct: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732

Query: 92   ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--G 142
              +        ++I  D I   R    +NG + + P       I  +   +K    A  G
Sbjct: 1733 RVVTVAALGTNISIHKDEIGKVR--VCVNGVLTALPVSVADGRISVAQGASKALLVADFG 1790

Query: 143  LTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQ 201
            L + ++    + + L + +    CGLCG+ +   +  +   +G L   +  +G   +   
Sbjct: 1791 LQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG 1850

Query: 202  PDVVCEDPEEEVAPASCSEHRAE-------CERLL--TAEAFADCQDLVPLEPYLRACQQ 252
             D +C D      P +C E R E       C  L   T   F  C   VP E + + C  
Sbjct: 1851 WDPLCWDECRGSCP-TCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVL 1909

Query: 253  DRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSP 312
            D C   G    +C  +A +   C  AG    +WR        G   TCP N  Y   G P
Sbjct: 1910 DVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-----GCEITCPENSHYEVCGPP 1964

Query: 313  CMDTC---SHLEVSSLCEEHRMDGCFCPEG 339
            C  +C   + L   ++CE   ++GC C  G
Sbjct: 1965 CPASCPSPAPLTTPAVCEGPCVEGCQCDAG 1994



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 88/337 (26%), Positives = 127/337 (37%), Gaps = 43/337 (12%)

Query: 33   GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAV---HLKRGPGQAEA 87
            G + C   G+ HY TFDG  F F G C Y  A  C  R     FAV   ++  G G+   
Sbjct: 1248 GSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 1307

Query: 88   PAGVESILLTIKDDTIYLTRH--LAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--GL 143
                  I + + + T+ L +      +NG  +  P       I  S   + V      GL
Sbjct: 1308 ---TRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 1364

Query: 144  TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL--SDGVLFSPLEFGNMQKINQ 201
             + ++    + + +   +    CGLCG+YNG     +F   +     +  EFGN  +   
Sbjct: 1365 RVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG-DPKDDFQKPNGSQAGNANEFGNSWEEVV 1423

Query: 202  PDVVCEDP------EEEVAPASCSEHRA--ECERLLTAEAF-----------ADCQDLVP 242
            PD  C  P       E+  P+    H+   E E+    E F           + C  LV 
Sbjct: 1424 PDSPCLPPTPCPPGSEDCIPS----HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVD 1479

Query: 243  LEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPG 302
             +  L+ C  D C   G  + +CS +  +   C  AGG    WRT T          CP 
Sbjct: 1480 PQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETF-----CPMECPP 1534

Query: 303  NLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEG 339
            N  Y      C   CS L     C++   +GC C  G
Sbjct: 1535 NSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSG 1571



 Score = 79.3 bits (194), Expect = 5e-14
 Identities = 74/323 (22%), Positives = 127/323 (39%), Gaps = 31/323 (9%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVESI 94
            C   G+ HY +FDG  F F G C Y     C    +   F V ++     ++  +   ++
Sbjct: 864  CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923

Query: 95   LLTIKDDTIYLTRHLAVLNGAVV--STPHYSPGLLIEKSDAYTKVYSRA---------GL 143
             +  +   + + R      G V+      Y P    + +D   +V+ +          GL
Sbjct: 924  RVEARGVKVAVRREYP---GQVLVDDVLQYLP---FQAADGQVQVFRQGRDAVVRTDFGL 977

Query: 144  TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL-SDGVLFSPLEFGNM-QKINQ 201
            T+ ++    +  ++ + +    CGLCG++NG  +    L   G   + L FGN  Q+  +
Sbjct: 978  TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETR 1037

Query: 202  PDVVCEDPEE----EVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQDRCR 256
            P     +P +    +   A   + + EC  L   +  F +C   +  +  +R C  DRC 
Sbjct: 1038 PGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL 1097

Query: 257  CPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDT 316
             PG    +C  +A ++  C  AG     WR+           +CP +  Y      C  +
Sbjct: 1098 LPGQSGPLCDALATYAAACQAAGATVHPWRSEEL-----CPLSCPPHSHYEACSYGCPLS 1152

Query: 317  CSHLEVSSLCEEHRMDGCFCPEG 339
            C  L V   C     +GC C EG
Sbjct: 1153 CGDLPVPGGCGSECHEGCVCDEG 1175



 Score = 36.6 bits (83), Expect = 0.34
 Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 11/92 (11%)

Query: 358  VVVFKSDGSVLL--------NELQVNLP-HVTASFSVFRPSSYHIMVSMAIGVRLQVQLA 408
            V +F  DG V L        N L+V+LP    AS SV R     ++V    GV++ +   
Sbjct: 2894 VHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGAN 2953

Query: 409  PVMQLFVTLDQASQGQVQGLCGNFNGLEGDDF 440
              + + V+ D A  G++ G CGNF+G + +D+
Sbjct: 2954 GKVAVIVSNDHA--GKLCGACGNFDGDQTNDW 2983


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score =  213 bits (542), Expect = 2e-54
 Identities = 293/1094 (26%), Positives = 404/1094 (36%), Gaps = 104/1094 (9%)

Query: 1278 VIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPT 1337
            V+ M F L   IN   C     P     +   +  P+    TT +T  PT ++ + T   
Sbjct: 521  VVAMGFIL---INPGTCPVKVLPELPPVSPVSSTGPSE---TTGLTENPTISTKKPTVSI 574

Query: 1338 PITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1396
               + TT  PT        PT  P I+T     P+  P       T P    T +T  PT
Sbjct: 575  EKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPT 634

Query: 1397 -PTGTQT-PTSTP-ITTTTTVTPTPTPTGTQTPTTTP-----ITTTTTVTPTPTPT-GTQ 1447
             P+   T P+  P I+T     PT  PT     TTT      I T     PT  P+  T+
Sbjct: 635  IPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTE 694

Query: 1448 APTPTAITTT-STVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTV 1506
             PT +   T  ST  PT +P     PT  P   T   T +P    T T  PT  T   T+
Sbjct: 695  KPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTI 754

Query: 1507 TPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTT 1566
            +P    T T+ PT +P   T    PT  PT         I T     PT  PT +    T
Sbjct: 755  SPEKPTTPTEKPTISPEKLT---IPTEKPT---------IPTEKPTIPTEKPTISTEEPT 802

Query: 1567 TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPT 1626
            TP   TT  T  P+    + PT  L T  TT +   T  ST+  T+ P+   T  T  PT
Sbjct: 803  TPTEETTISTEKPS-IPMEKPT--LPTEETTTSVEETTISTEKLTI-PMEKPTISTEKPT 858

Query: 1627 PTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRS 1686
               T+ PT+ P   T    PT   T      PT   T PI E T S    E  T  T + 
Sbjct: 859  -IPTEKPTISPEKLT---IPTEKLTI-----PTEKPTIPIEETTIST---EKLTIPTEKP 906

Query: 1687 TSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPP--GTPTR 1744
            T SP  E  T +ST  P I    T  P+ PT  TT S      P    T SP     PT 
Sbjct: 907  TISP--EKPT-ISTEKPTI---PTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE 960

Query: 1745 GTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLR-PYPSSVLI-CCVLNDTY 1802
              T  S+  PT  T + T  +     PT   T    + T LR P+PS        L  + 
Sbjct: 961  KPTI-STEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSP 1019

Query: 1803 YAPGEEVYNGTYGDTCYFVNCSLSC--TLEFYNWSCPS---TPSPTPTPSKSTPTPSKPS 1857
            +AP   + +   G T    + +  C     + + +CP+   +P P+  P         P 
Sbjct: 1020 HAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPG 1079

Query: 1858 STPSKPTPGTKPPECPDF--DPPRQENETWWLCDCF-MATCKYNNTVEIVKVECEPPPMP 1914
               S      +   C  F  +   +    W+  +C     C   + VE    +C    + 
Sbjct: 1080 FLFS-DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVC 1138

Query: 1915 TCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPS 1974
               NG            C  +     C  +GDPHYVTFDG ++ + G CTY+L +    S
Sbjct: 1139 QLKNGQYG---------CHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNS 1189

Query: 1975 VDNFGVYIDNYHCDPNDKVSC-PRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP- 2032
             D F            + VSC  +  +   E+   L+K    +       V  Q V LP 
Sbjct: 1190 TDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTL-------VGGQQVTLPA 1242

Query: 2033 YKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDD 2092
                G+ +  SG  +V    E G+ V ++G           +     G CG     + +D
Sbjct: 1243 IPSKGVFLGASG-RFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDND 1301

Query: 2093 CILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL 2152
             +   G    + E   + W  +      C       K   V  P    +       P   
Sbjct: 1302 HLKLDGSPAGDKEELGNSWQTDQDEDQEC------QKYQVVNSPSCDSSLQSSMSGPG-F 1354

Query: 2153 CQLIKDS--LFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNICLD 2209
            C  + D+   F  C   V    ++D+C+ D C   G   L C  +      C      + 
Sbjct: 1355 CGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVK 1414

Query: 2210 WRNHTHGACLVECPSHREYQACGPAEEPTCKSS-SSQQNNTVLVEGCFCPEGTMNYAPGF 2268
                 H  C + CP + +Y  C      TC S  S    +   VE C C  G +    G 
Sbjct: 1415 PWREPH-FCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFV--LSGL 1471

Query: 2269 DVCVKT-CGCVGPDNVPREFGEH-FEFDCKN-CVCLEGGSGIICQPKRCSQKPVTHCVED 2325
            +   ++ CGC+ P     + GE  ++  CK  CVC E  + I CQP RC  +      +D
Sbjct: 1472 ECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVC-ESNNRIRCQPWRCRAQEFCG-QQD 1529

Query: 2326 GTYLATEVNPADTC 2339
            G Y       A TC
Sbjct: 1530 GIY-GCHAQGAATC 1542



 Score =  166 bits (421), Expect = 2e-40
 Identities = 201/852 (23%), Positives = 319/852 (37%), Gaps = 161/852 (18%)

Query: 314  MDTCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSDGS------V 367
            M TC+++ ++  C     D  F       +    + +   K  +V VF    S      V
Sbjct: 1561 MGTCTYV-LTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKV 1619

Query: 368  LLNELQVNLPHVTASFSV-FRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQ 426
            +LN  +V LP   A   V  R SS  +++    G++++   + +++  VT+  +  GQ+ 
Sbjct: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVE--VTVPSSYGGQLC 1677

Query: 427  GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAE 486
            GLCGN+N    DD       +          WK   S       +    S + +  + A+
Sbjct: 1678 GLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPS-SCQENSMAD 1736

Query: 487  HW---CSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAK 543
             W   C++L   + PF +CH  V P   +  C +  C  + +   LC +L +YA  C   
Sbjct: 1737 AWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796

Query: 544  GVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCP 602
            G     WR    C      CP    +    + C  TC S++           P D   CP
Sbjct: 1797 G-QAPAWRNRTFCPM---RCPPGSSYSPCSSPCPDTCSSINN----------PRD---CP 1839

Query: 603  DHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTA 662
                     + +P A                     E C C+ G +      L G SC  
Sbjct: 1840 ---------KALPCA---------------------ESCECQKGHI------LSGTSCV- 1862

Query: 663  PKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECP 722
            P     C++                  AG YH         P G        C   + C 
Sbjct: 1863 PLGQCGCTD-----------------PAGSYH---------PVGERWYTENTCT--RLCT 1894

Query: 723  C-VHNNDLYSSGAKIKVDCNTCTCKRGRWVC--------TQAVCHGTCSIYGSGHYITFD 773
            C VHNN          + C   TCK  + +C         +A   G C + G  HY++FD
Sbjct: 1895 CSVHNN----------ITCFQSTCKPNQ-ICWALDGLLRCRASGVGVCQLPGESHYVSFD 1943

Query: 774  GKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPC-GTTGVTCSKAIKIFMGRTELKL 832
            G  +     C+ V V+  C    +L  F I  ++    G T       + I +   ++ L
Sbjct: 1944 GSNHSIPDACTLVLVK-VCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTL 2002

Query: 833  EDKHRVVIQRDE------GHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYK 886
            +  HRV+I   +            + +    Y +V    G+ V +D    + I++  +Y 
Sbjct: 2003 QKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYY 2062

Query: 887  GTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDV-----------S 932
            G VCG+CGNF+    ++       V +S+ +F NSWK+    P+C  +            
Sbjct: 2063 GKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQ 2122

Query: 933  TNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECF 992
             NP         R   EK  + L++ V++ C S++D  PF   C   +  C+ GG  +  
Sbjct: 2123 ENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCA--NTLCEFGGLYQAL 2180

Query: 993  CSAVASYAQECTKEG-ACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTING 1051
            C A+ ++   C  +G     WR    CP+ C  Y+        Y  C      +C  ++G
Sbjct: 2181 CQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS-------SYTNCLPSCSPSCWDLDG 2233

Query: 1052 IHSNISV--SYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTH---YPPGASVPTE 1106
                  V  +  EGC   C   +P Y     KCV   +CGC  +D H    P G S  + 
Sbjct: 2234 RCEGAKVPSACAEGCI--C---QPGYVLSEDKCVPRSQCGC--KDAHGGSIPLGKSWVSS 2286

Query: 1107 ETCKSCVCTNSS 1118
               + CVCT  +
Sbjct: 2287 GCTEKCVCTGGA 2298



 Score =  165 bits (417), Expect = 6e-40
 Identities = 126/477 (26%), Positives = 199/477 (41%), Gaps = 79/477 (16%)

Query: 697  CVSGCVCPDG-LMDDGRGGCVVEKECPCVHNNDLYSSGAK---------------IKVDC 740
            C  GCVC  G L  D    C+    C C +NND Y  GA+                +V+C
Sbjct: 1070 CREGCVCNPGFLFSDNH--CIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVEC 1127

Query: 741  N--------TCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYC 792
                      C  K G++ C       TC +YG  HY+TFDG+++ F G C+Y+  Q  C
Sbjct: 1128 QISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C 1186

Query: 793  GQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTT 852
            G NS+   F +  +N   G  GV+C   + + +  + + L    R ++   +    A  +
Sbjct: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPS 1245

Query: 853  REV-----GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTR 907
            + V     G+++ +++  G+ V WD    +++ ++ +Y G +CGLCGN+D  S+ND    
Sbjct: 1246 KGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305

Query: 908  DHMVVSSELDFGNSWK----EAPTCPDVS-TNPEPCSLNPHRRSWAEKQCSILKSS--VF 960
            D      + + GNSW+    E   C      N   C  +          C  L  +   F
Sbjct: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPF 1365

Query: 961  SICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCP 1019
              C   V    F+++C+ D C     G     C+ +++    C   G  V  WR P  CP
Sbjct: 1366 ETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCP 1423

Query: 1020 IFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKD---RPIYE 1076
            + C    PP+     Y  C     +TC      HS  S  +   C  RC +     P + 
Sbjct: 1424 MAC----PPNS---KYSLCAKPCPDTC------HSGFSGMF---CSDRCVEACECNPGFV 1467

Query: 1077 EDLKKCVTADKCGCY--------VEDTHYPPGASVPTEETCKS-CVCTNSSQVVCRP 1124
                +C+   +CGC         V +  Y PG        CK  CVC +++++ C+P
Sbjct: 1468 LSGLECIPRSQCGCLHPAGSYFKVGERWYKPG--------CKELCVCESNNRIRCQP 1516



 Score =  164 bits (414), Expect = 1e-39
 Identities = 139/497 (27%), Positives = 206/497 (41%), Gaps = 81/497 (16%)

Query: 678  SKPRALSCQTLAAGYYHTE-CVSGCVCPDGLMDDGRGGCVVEKECPCVH--------NND 728
            +KP   +C +  +G + ++ CV  C C  G +  G   C+   +C C+H           
Sbjct: 1436 AKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLE-CIPRSQCGCLHPAGSYFKVGER 1494

Query: 729  LYSSGAKIKVDC---NTCTCK----RGRWVCTQAV----CHG----TCSIYGSGHYITFD 773
             Y  G K    C   N   C+    R +  C Q      CH     TC+  G  HY+TFD
Sbjct: 1495 WYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFD 1554

Query: 774  GKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRTELKL 832
            G  + F G C+YV  +  C   S    F +   N   G    V+  KA+ + +    + L
Sbjct: 1555 GALHHFMGTCTYVLTRP-CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISL 1613

Query: 833  EDKHRVVIQRDEGHHVAY---------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAP 883
                +V++    GH VA          T R     +++ ++ G+ V +D    V + +  
Sbjct: 1614 LRGCKVMLN---GHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPS 1670

Query: 884  SYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK----EAPTCPDVSTNPEPCS 939
            SY G +CGLCGN+++ S +D    D  +    +  G +WK      P C  V   P  C 
Sbjct: 1671 SYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQ 1730

Query: 940  LNPHRRSWAEKQCSIL--KSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVA 997
             N    +W  K C+IL      FS CH  V P+  + +CVH  C   T GD    C ++ 
Sbjct: 1731 ENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG--TKGDTTALCRSLQ 1787

Query: 998  SYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNIS 1057
            +YA  C + G    WR    CP+ C    PP      Y PC +   +TC +IN       
Sbjct: 1788 AYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSPCPDTCSSINN------ 1834

Query: 1058 VSYLEGCYPR-CPKDRPIYEE-DLKK--------CVTADKCGCY-VEDTHYPPGASVPTE 1106
                    PR CPK  P  E  + +K        CV   +CGC     +++P G    TE
Sbjct: 1835 --------PRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTE 1886

Query: 1107 ETC-KSCVCTNSSQVVC 1122
             TC + C C+  + + C
Sbjct: 1887 NTCTRLCTCSVHNNITC 1903



 Score =  128 bits (321), Expect = 9e-29
 Identities = 119/455 (26%), Positives = 172/455 (37%), Gaps = 52/455 (11%)

Query: 1883 ETWWLCDCF-MATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYC 1941
            E W+   C  +  C+ NN +      C         +G+         GC  H +    C
Sbjct: 1493 ERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIY--------GC--HAQGAATC 1542

Query: 1942 TGWGDPHYVTFDGLYYSYQGNCTYVLVEEI-SPSVDN-FGVYIDNYHCDPNDKVSCPRTL 1999
            T  GDPHY+TFDG  + + G CTYVL     S S D+ F V   N +     +VS     
Sbjct: 1543 TASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVS----- 1597

Query: 2000 IVRHETQEVLIKTVHMMPMQV--------QVQVNRQAVALP-YKKYGLEVYQSGINYVVD 2050
                      IK VH+    +        +V +N   VALP +   G    +   N V+ 
Sbjct: 1598 ---------YIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLL 1648

Query: 2051 IPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQ 2110
                G+ V Y+G           +G    G CG   N + DD + P  ++  +       
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708

Query: 2111 WLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPP 2170
            W + + S+P C        +P+           +K+C       +     F+QCH +VPP
Sbjct: 1709 WKLPESSEPGC---FLVGGKPSSCQENSMADAWNKNCA----ILINPQGPFSQCHQVVPP 1761

Query: 2171 QHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQ 2229
            Q  + +CV   C   G +   C SLQAYA+LCAQ      WRN T   C + CP    Y 
Sbjct: 1762 QSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTF--CPMRCPPGSSYS 1819

Query: 2230 ACGPAEEPTCKSSSSQQN---NTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 2286
             C      TC S ++ ++        E C C +G +       V +  CGC  P      
Sbjct: 1820 PCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSC-VPLGQCGCTDPAGSYHP 1878

Query: 2287 FGEHF--EFDCKNCVCLEGGSGIICQPKRCSQKPV 2319
             GE +  E  C         + I C    C    +
Sbjct: 1879 VGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQI 1913



 Score =  128 bits (321), Expect = 9e-29
 Identities = 174/771 (22%), Positives = 276/771 (35%), Gaps = 155/771 (20%)

Query: 359  VVFKSDGSVLLNELQVNLPHVTASFSV-FRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTL 417
            V  +    VL+N  QV LP ++    V  + SS + +V++ IGV  QV+      L + +
Sbjct: 2000 VTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGV--QVKFDGNHLLEIEI 2057

Query: 418  DQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS---SCHDKL------ 468
                 G+V G+CGNFN  E D+    S  V  + + F N+WK +    SC   L      
Sbjct: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQI 2117

Query: 469  --DWLDDPCSLNIESANY--AEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQN 524
              +  ++P S N  +A+   A   C    +    + +C S +D   +   C    C    
Sbjct: 2118 PAEQQENP-SGNCRAADLRRAREKCEAALRAPV-WAQCASRIDLTPFLVDCANTLCEFGG 2175

Query: 525  NEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE 584
                LC AL ++   C ++G+    WR                                 
Sbjct: 2176 LYQALCQALQAFGATCQSQGLKPPLWRN-------------------------------- 2203

Query: 585  ADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCR 644
                    F P++   CP ++       C+P    SC+      E   V     E C+C+
Sbjct: 2204 ------SSFCPLE---CPAYSSYTN---CLPSCSPSCWDLDGRCEGAKVPSACAEGCICQ 2251

Query: 645  DGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCP 704
             G +       + +    P+    C +  A   S P       L   +  + C   CVC 
Sbjct: 2252 PGYV-------LSEDKCVPRSQCGCKD--AHGGSIP-------LGKSWVSSGCTEKCVCT 2295

Query: 705  DGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIY 764
             G +  G   C     C    +N             + C   +             CS+Y
Sbjct: 2296 GGAIQCGDFRCPSGSHCQLTSDNSN-----------SNCVSDKSE----------QCSVY 2334

Query: 765  GSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITEN-VPCGTTGVTCSKAIKI 823
            G   Y+TFDG  Y   G  +YV ++        +    +   N +    + +   + I  
Sbjct: 2335 GDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITT 2394

Query: 824  FMG---RTELKLE---DKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTV 877
              G   + +  LE   +  ++ +      H+  T    GQ L + +   ++V +  R   
Sbjct: 2395 VYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLW--GQRLYLVTDFELVVSFGGRKNA 2452

Query: 878  FIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSW------------KEA 925
             I L   Y+G V GLCGN+D    ND       +  +   FGNSW            +  
Sbjct: 2453 VISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAI 2512

Query: 926  PTCPD-------VSTNPEPCSLNPHR-RSWAEKQCSIL--KSSVFSICHSKVDPKPFYEA 975
            P   +       + T  +    +P +  S + + C +L      F+ CH  V P+PF E 
Sbjct: 2513 PAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEH 2572

Query: 976  CVHDSCSC-DTGGDCECFCSAVASYAQECTKEGACVFWRTPD-LC----------PIFCD 1023
            CV D CS  D     E  C  ++ +        + ++   P  LC          P+   
Sbjct: 2573 CVLDLCSAQDPREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGPLRGR 2632

Query: 1024 YYNPPHEC-EWHYEP----CGNRSFETCRTINGIHSNISVSYL-EGCYPRC 1068
                P  C +WH EP    CG      C T NGI+  +  S+L E C  RC
Sbjct: 2633 LRQHPRLCLQWHPEPPLADCG------C-TSNGIYYQLGSSFLTEDCSQRC 2676



 Score =  111 bits (277), Expect = 1e-23
 Identities = 144/566 (25%), Positives = 198/566 (34%), Gaps = 67/566 (11%)

Query: 1326 PTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 1382
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533

Query: 1383 TPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1442
             P+     + P    + T    +T +T   T++        + P+   +TT     P   
Sbjct: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590

Query: 1443 PT-GTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAIT 1501
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +   P+   
Sbjct: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647

Query: 1502 TTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQT-PTPTPISTTT--TVTPTPTP 1558
            T +T  PT     T+ PT+    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704

Query: 1559 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTT 1618
              T+ PT +P   T    PT  PT     +T+     TT T  PT  + K T      TT
Sbjct: 705  ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT 761

Query: 1619 TTVTATPTPTGTQTPTMIP-ISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPE 1677
             T   T +P     PT  P I T     PT  PT  +  P T T    I+    S P  +
Sbjct: 762  PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEK 821

Query: 1678 SSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTT-- 1735
             + P    +TS   T  +T   T+P      ST  P+ PT   T S      P    T  
Sbjct: 822  PTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIP 881

Query: 1736 TSPPGTPTRGTTTGSSSAPTPS---TVQTTTTSAWTPTPT-PLSTPSIIRTTGLRPYPSS 1791
            T  P  P   TT  +     P+   T+     +  T  PT P   P+I            
Sbjct: 882  TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTI------------ 929

Query: 1792 VLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTP 1851
                         P EE    T           L+   E    S      PT  P+ ST 
Sbjct: 930  -------------PTEETTISTE---------KLTIPTEKPTISPEKLTIPTEKPTISTE 967

Query: 1852 TPSKPSST----PSKPTPGTKPPECP 1873
             P+ P+        KPT  T+ P  P
Sbjct: 968  KPTIPTEKLTIPTEKPTIPTEKPTIP 993



 Score =  105 bits (261), Expect = 8e-22
 Identities = 96/343 (27%), Positives = 136/343 (39%), Gaps = 42/343 (12%)

Query: 28   RTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGS-----YKEFAVHLKRGP 82
            R R  G  VC   G  HY +FDG     P  C       C  +     +K  A H K   
Sbjct: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKE-E 1980

Query: 83   GQAEAPAGVESILLTIKDDTIYLTR-HLAVLNGAVVSTPHYS--PGLLIEKSDAYTKVYS 139
            G  EA   +  + + I D  + L + H  ++N   V+ P  S  PG+ ++ S  Y+ V  
Sbjct: 1981 GGTEA-FRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI 2039

Query: 140  RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL-SDGVLFSPLEFGNMQK 198
            + G+ + ++    L +E+ T +    CG+CG++N  +     + SD V  S  EF N  K
Sbjct: 2040 KIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWK 2099

Query: 199  INQPDVVCED--PEEEVAPASCSEH-------------RAECERLLTAEAFADCQDLVPL 243
                D  C+    +E+  PA   E+             R +CE  L A  +A C   + L
Sbjct: 2100 DKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDL 2159

Query: 244  EPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGN 303
             P+L  C    C   G    +C  +  F   C   G +P  WR      S      CP  
Sbjct: 2160 TPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRN-----SSFCPLECPAY 2214

Query: 304  LVY---LESGSP-CMD---TCSHLEVSSLCEEHRMDGCFCPEG 339
              Y   L S SP C D    C   +V S C E    GC C  G
Sbjct: 2215 SSYTNCLPSCSPSCWDLDGRCEGAKVPSACAE----GCICQPG 2253



 Score =  103 bits (258), Expect = 2e-21
 Identities = 83/322 (25%), Positives = 130/322 (40%), Gaps = 23/322 (7%)

Query: 33   GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEF-AVHLKRGPGQAEAPAGV 91
            G   C  +G+ HY TFDG  F F G C Y  A  C  S   F  V  K      E  + +
Sbjct: 1152 GTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCL 1211

Query: 92   ESILLTIKDDTIYLTR-HLAVLNGAVVSTPHY-SPGLLIEKSDAYTKVYSRAGLTLMWNR 149
              + +T+ + T+ L +    ++ G  V+ P   S G+ +  S  + ++ +  GL + W+ 
Sbjct: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDG 1271

Query: 150  EDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL----EFGNMQKINQ-PDV 204
            +  L + + + +    CGLCG+Y+G         DG   SP     E GN  + +Q  D 
Sbjct: 1272 DQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDG---SPAGDKEELGNSWQTDQDEDQ 1328

Query: 205  VCEDPEEEVAPASCSEHRAE------CERLL-TAEAFADCQDLVPLEPYLRACQQDRCRC 257
             C+  +   +P+  S  ++       C RL+ T   F  C   V    +  +C  D C  
Sbjct: 1329 ECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGF 1388

Query: 258  PGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTC 317
             G    +C+ ++  +  C  AG     WR             CP N  Y     PC DTC
Sbjct: 1389 QGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHF-----CPMACPPNSKYSLCAKPCPDTC 1443

Query: 318  SHLEVSSLCEEHRMDGCFCPEG 339
                    C +  ++ C C  G
Sbjct: 1444 HSGFSGMFCSDRCVEACECNPG 1465



 Score =  102 bits (255), Expect = 4e-21
 Identities = 90/358 (25%), Positives = 145/358 (40%), Gaps = 31/358 (8%)

Query: 312  PCMD-TCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSDGSVLLN 370
            PC + T     V++  EE   +G  C       LP++ V L   ++ +V           
Sbjct: 1185 PCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLV----------G 1234

Query: 371  ELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCG 430
              QV LP + +       S   + +    G+R  V+     QL+VT+     G++ GLCG
Sbjct: 1235 GQQVTLPAIPSKGVFLGASGRFVELQTEFGLR--VRWDGDQQLYVTVSSTYSGKLCGLCG 1292

Query: 431  NFNGLEGDDFKTASGLVEATGAGFANTWKAQSS----CHDKLDWLDDP-CSLNIESANYA 485
            N++G   +D     G          N+W+        C  K   ++ P C  +++S+   
Sbjct: 1293 NYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQ-KYQVVNSPSCDSSLQSSMSG 1351

Query: 486  EHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGV 545
              +C  L  T  PF  C   V  A ++  C  D C  Q  +  LC  +S+    C   G 
Sbjct: 1352 PGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGH 1411

Query: 546  MLWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDH 604
             +  WRE H C     +CP +  +      C  TC S   +   C +    V+ C C + 
Sbjct: 1412 AVKPWREPHFCPM---ACPPNSKYSLCAKPCPDTCHS-GFSGMFCSD--RCVEACEC-NP 1464

Query: 605  TFLDEKGRCVPLAKCSCYH-RGLYLEAGDVVVRQ--EERCVCR-DGRLHCRQIRLIGQ 658
             F+     C+P ++C C H  G Y + G+   +   +E CVC  + R+ C+  R   Q
Sbjct: 1465 GFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQ 1522



 Score =  100 bits (250), Expect = 1e-20
 Identities = 113/488 (23%), Positives = 184/488 (37%), Gaps = 68/488 (13%)

Query: 1892 MATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVT 1951
            + TC  +N +   +  C+P  +    +GL   R      C             G+ HYV+
Sbjct: 1892 LCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLP----------GESHYVS 1941

Query: 1952 FDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIK 2011
            FDG  +S    CT VLV+   P++      I   H    +K          HE    +  
Sbjct: 1942 FDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKH----EKEEGGTEAFRLHEVYIDIYD 1997

Query: 2012 TVHMMPMQVQVQVNRQAVALPYKKY--GLEVYQSGINYVVDIPELGVLVSYNGLS-FSVR 2068
                +    +V +N + V LP      G+ V  S I  +V+I ++GV V ++G     + 
Sbjct: 1998 AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI-KIGVQVKFDGNHLLEIE 2056

Query: 2069 LPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTT 2128
            +P   +G    G CG   +   D+ ++PS E+ ++     + W   D   P C       
Sbjct: 2057 IPTTYYG-KVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD-IDPSCQSLLVDE 2114

Query: 2129 KRPAVTVPGGGKTTPHKDCTPSPL------CQ-LIKDSLFAQCHALVPPQHYYDACVFDS 2181
            ++    +P   +  P  +C  + L      C+  ++  ++AQC + +    +   C    
Sbjct: 2115 QQ----IPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTL 2170

Query: 2182 CFMPG-SSLECASLQAYAALCAQQNICLD-WRNHTHGACLVECPSHREYQACGPAEEPTC 2239
            C   G     C +LQA+ A C  Q +    WRN +   C +ECP++  Y  C P+  P+C
Sbjct: 2171 CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSF--CPLECPAYSSYTNCLPSCSPSC 2228

Query: 2240 KSSSSQQNN----TVLVEGCFCPEGTMNYAPGFDVCV--KTCGCVGPDNVPREFGEHFEF 2293
                 +       +   EGC C  G   Y    D CV    CGC          G+ +  
Sbjct: 2229 WDLDGRCEGAKVPSACAEGCICQPG---YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVS 2285

Query: 2294 D--CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSL 2351
                + CVC   G  I C   RC                    P+ + C +T    N++ 
Sbjct: 2286 SGCTEKCVCT--GGAIQCGDFRC--------------------PSGSHCQLTSDNSNSNC 2323

Query: 2352 CKEKPSVC 2359
              +K   C
Sbjct: 2324 VSDKSEQC 2331



 Score = 99.4 bits (246), Expect = 4e-20
 Identities = 132/524 (25%), Positives = 186/524 (35%), Gaps = 77/524 (14%)

Query: 1372 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTST---PITTTTTVTPTPTPTGTQTPTT 1428
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533

Query: 1429 TPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1488
             P+     + P    + T     T +T   T++        + P+   +TT     P   
Sbjct: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590

Query: 1489 PTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPIST 1548
            PT   T  PT  T   T+ P+  P       + P    T +T  PT    +   P+   T
Sbjct: 591  PT-IPTEKPTISTEKPTI-PSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPT 648

Query: 1549 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTK 1608
             +T  PT     T+ PTT    TTT++     PT  + P+   I T     PT  PT   
Sbjct: 649  ISTEKPT---VPTEEPTTPTEETTTSMEEPVIPT--EKPS---IPTEKPSIPTEKPT--- 697

Query: 1609 STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAE 1668
                  I+   T+ +T  PT +     IP    T  T   T +      PT   T P  +
Sbjct: 698  ------ISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEK 751

Query: 1669 LTTSNPPPESSTPQTSRSTSSPL-----TESTTLLS---TLPPAIEMTSTAPPSTPTAPT 1720
             T S   PE  T  T + T SP      TE  T+ +   T+P      ST  P+TPT  T
Sbjct: 752  PTIS---PEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEET 808

Query: 1721 TTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSII 1780
            T S     +  PS     P  PT  TTT         +V+ TT S    T  P+  P+I 
Sbjct: 809  TIS-----TEKPSIPMEKPTLPTEETTT---------SVEETTISTEKLT-IPMEKPTIS 853

Query: 1781 RTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTP 1840
                  P         +  +    P E++                  T+     + P   
Sbjct: 854  TEKPTIPTEKPT----ISPEKLTIPTEKL------------------TIPTEKPTIPIEE 891

Query: 1841 SPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENET 1884
            +   T   + PT  KP+ +P KPT  T+ P  P   P     ET
Sbjct: 892  TTISTEKLTIPT-EKPTISPEKPTISTEKPTIPTEKPTIPTEET 934



 Score = 94.0 bits (232), Expect = 2e-18
 Identities = 82/327 (25%), Positives = 132/327 (40%), Gaps = 31/327 (9%)

Query: 33   GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVH-LKRGPGQAEAPA 89
            G   C+  G+ HY TFDG +  F G C Y     C  R     F V       G     +
Sbjct: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVS 1597

Query: 90   GVESILLTIKDDTIYLTRHLAV-LNGAVVSTPHY--SPGLLIEKSDAYTKVYSRAGLTLM 146
             ++++ +T+ D +I L R   V LNG  V+ P +     + I  S     +Y+  GL + 
Sbjct: 1598 YIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657

Query: 147  WNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVC 206
            ++    + + + + +    CGLCG+YN     +  L D +       G+  ++     + 
Sbjct: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYN-----NNSLDDNLRPDRKLAGDSMQLGAAWKLP 1712

Query: 207  EDPEEEV-----APASCSEH------RAECERLLTAEA-FADCQDLVPLEPYLRACQQDR 254
            E  E         P+SC E+         C  L+  +  F+ C  +VP +    +C   +
Sbjct: 1713 ESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQ 1772

Query: 255  CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCM 314
            C   G  T +C ++  ++  C+ AG  P  WR  T          CP    Y    SPC 
Sbjct: 1773 CGTKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTF-----CPMRCPPGSSYSPCSSPCP 1826

Query: 315  DTCSHLEVSSLCEEHR--MDGCFCPEG 339
            DTCS +     C +     + C C +G
Sbjct: 1827 DTCSSINNPRDCPKALPCAESCECQKG 1853



 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 69/257 (26%), Positives = 113/257 (43%), Gaps = 24/257 (9%)

Query: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000
            C+ +GDP Y+TFDG  Y  QG  TYVL++    +VD     ++    +  +K+  PR+ I
Sbjct: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIK----TVDVLPEGVEPLLVEGRNKMDPPRSSI 2386

Query: 2001 VRHETQEVLIKTVHMMPMQVQ----VQVNRQAVALPYK-KYGLEVYQSGINYVVDIPELG 2055
               E    +I TV+   +Q+Q    + VN Q +A+PY+    L V   G    + + +  
Sbjct: 2387 FLQE----VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYL-VTDFE 2441

Query: 2056 VLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV-N 2114
            ++VS+ G   +V      +     G CG       +D +LPSG +  N     + W V  
Sbjct: 2442 LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKT 2501

Query: 2115 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL-------CQLIKD--SLFAQCH 2165
            + +    P +    +       G        +C+P  L       C+++ D    FA CH
Sbjct: 2502 EDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACH 2561

Query: 2166 ALVPPQHYYDACVFDSC 2182
              V P+ + + CV D C
Sbjct: 2562 QTVAPEPFQEHCVLDLC 2578



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 99/375 (26%), Positives = 134/375 (35%), Gaps = 75/375 (20%)

Query: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPI 1615
            P P   +  +  P    T+VT    P+G Q P   LI      + T +  +     + P 
Sbjct: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQ-LIFKGIQGSNTASVVAMGFILINPG 532

Query: 1616 TTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAEL-----T 1670
            T        P     + P + P+S+T      P+ TTG T  PT ++  P   +     T
Sbjct: 533  TC-------PVKVLPELPPVSPVSSTG-----PSETTGLTENPTISTKKPTVSIEKPSVT 580

Query: 1671 TSNP--PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTA----PTTTSG 1724
            T  P  P E  T  T + T S  TE  T+ S  P       T P   PT     PT  S 
Sbjct: 581  TEKPTVPKEKPTIPTEKPTIS--TEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSE 638

Query: 1725 GHTL-SPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTT 1783
              T+ S  P+ +T  P  PT   TT     PT    + TTTS   P   P   PSI    
Sbjct: 639  KPTIPSEKPTISTEKPTVPTEEPTT-----PT----EETTTSMEEPV-IPTEKPSI---- 684

Query: 1784 GLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPT 1843
                                 P E+    T   T       +S      +   P+ P+  
Sbjct: 685  ---------------------PTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEK 723

Query: 1844 PT--PSKSTPTPSKPSSTPSKPT-PGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNT 1900
            PT    KST +P KP++   KPT P  KP   P+      E  T       ++  K    
Sbjct: 724  PTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPT-------ISPEKLTIP 776

Query: 1901 VEIVKVECEPPPMPT 1915
             E   +  E P +PT
Sbjct: 777  TEKPTIPTEKPTIPT 791



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 52/249 (20%), Positives = 90/249 (36%), Gaps = 31/249 (12%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAG---VES 93
            CS +G+  Y TFDG  +R  G   Y          +     L  G  + + P     ++ 
Sbjct: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390

Query: 94   ILLTIKDDTIYLTRHL-AVLNGAVVSTPHYSPGLLIEKSDAYTKVY--SRAGLTLMWNRE 150
            ++ T+    + L   L  V+N   ++ P Y P   +  +    ++Y  +   L + +   
Sbjct: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVP-YRPNEHLRVTLWGQRLYLVTDFELVVSFGGR 2449

Query: 151  DALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVVCEDP 209
               ++ L + +     GLCG+Y+  +     L  G L   L  FGN  ++   D +   P
Sbjct: 2450 KNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFP 2509

Query: 210  E---------------------EEVAPASCSEHRAECERLLT--AEAFADCQDLVPLEPY 246
                                   E +P   + +  +  R+L      FA C   V  EP+
Sbjct: 2510 RAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPF 2569

Query: 247  LRACQQDRC 255
               C  D C
Sbjct: 2570 QEHCVLDLC 2578


>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score =  213 bits (542), Expect = 2e-54
 Identities = 293/1094 (26%), Positives = 404/1094 (36%), Gaps = 104/1094 (9%)

Query: 1278 VIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPT 1337
            V+ M F L   IN   C     P     +   +  P+    TT +T  PT ++ + T   
Sbjct: 521  VVAMGFIL---INPGTCPVKVLPELPPVSPVSSTGPSE---TTGLTENPTISTKKPTVSI 574

Query: 1338 PITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1396
               + TT  PT        PT  P I+T     P+  P       T P    T +T  PT
Sbjct: 575  EKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPT 634

Query: 1397 -PTGTQT-PTSTP-ITTTTTVTPTPTPTGTQTPTTTP-----ITTTTTVTPTPTPT-GTQ 1447
             P+   T P+  P I+T     PT  PT     TTT      I T     PT  P+  T+
Sbjct: 635  IPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTE 694

Query: 1448 APTPTAITTT-STVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTV 1506
             PT +   T  ST  PT +P     PT  P   T   T +P    T T  PT  T   T+
Sbjct: 695  KPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTI 754

Query: 1507 TPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTT 1566
            +P    T T+ PT +P   T    PT  PT         I T     PT  PT +    T
Sbjct: 755  SPEKPTTPTEKPTISPEKLT---IPTEKPT---------IPTEKPTIPTEKPTISTEEPT 802

Query: 1567 TPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPT 1626
            TP   TT  T  P+    + PT  L T  TT +   T  ST+  T+ P+   T  T  PT
Sbjct: 803  TPTEETTISTEKPS-IPMEKPT--LPTEETTTSVEETTISTEKLTI-PMEKPTISTEKPT 858

Query: 1627 PTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRS 1686
               T+ PT+ P   T    PT   T      PT   T PI E T S    E  T  T + 
Sbjct: 859  -IPTEKPTISPEKLT---IPTEKLTI-----PTEKPTIPIEETTIST---EKLTIPTEKP 906

Query: 1687 TSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPP--GTPTR 1744
            T SP  E  T +ST  P I    T  P+ PT  TT S      P    T SP     PT 
Sbjct: 907  TISP--EKPT-ISTEKPTI---PTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTE 960

Query: 1745 GTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLR-PYPSSVLI-CCVLNDTY 1802
              T  S+  PT  T + T  +     PT   T    + T LR P+PS        L  + 
Sbjct: 961  KPTI-STEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSP 1019

Query: 1803 YAPGEEVYNGTYGDTCYFVNCSLSC--TLEFYNWSCPS---TPSPTPTPSKSTPTPSKPS 1857
            +AP   + +   G T    + +  C     + + +CP+   +P P+  P         P 
Sbjct: 1020 HAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPSCGPLCREGCVCNPG 1079

Query: 1858 STPSKPTPGTKPPECPDF--DPPRQENETWWLCDCF-MATCKYNNTVEIVKVECEPPPMP 1914
               S      +   C  F  +   +    W+  +C     C   + VE    +C    + 
Sbjct: 1080 FLFS-DNHCIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVC 1138

Query: 1915 TCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPS 1974
               NG            C  +     C  +GDPHYVTFDG ++ + G CTY+L +    S
Sbjct: 1139 QLKNGQYG---------CHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNS 1189

Query: 1975 VDNFGVYIDNYHCDPNDKVSC-PRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP- 2032
             D F            + VSC  +  +   E+   L+K    +       V  Q V LP 
Sbjct: 1190 TDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTL-------VGGQQVTLPA 1242

Query: 2033 YKKYGLEVYQSGINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDD 2092
                G+ +  SG  +V    E G+ V ++G           +     G CG     + +D
Sbjct: 1243 IPSKGVFLGASG-RFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDND 1301

Query: 2093 CILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL 2152
             +   G    + E   + W  +      C       K   V  P    +       P   
Sbjct: 1302 HLKLDGSPAGDKEELGNSWQTDQDEDQEC------QKYQVVNSPSCDSSLQSSMSGPG-F 1354

Query: 2153 CQLIKDS--LFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNICLD 2209
            C  + D+   F  C   V    ++D+C+ D C   G   L C  +      C      + 
Sbjct: 1355 CGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVK 1414

Query: 2210 WRNHTHGACLVECPSHREYQACGPAEEPTCKSS-SSQQNNTVLVEGCFCPEGTMNYAPGF 2268
                 H  C + CP + +Y  C      TC S  S    +   VE C C  G +    G 
Sbjct: 1415 PWREPH-FCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFV--LSGL 1471

Query: 2269 DVCVKT-CGCVGPDNVPREFGEH-FEFDCKN-CVCLEGGSGIICQPKRCSQKPVTHCVED 2325
            +   ++ CGC+ P     + GE  ++  CK  CVC E  + I CQP RC  +      +D
Sbjct: 1472 ECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVC-ESNNRIRCQPWRCRAQEFCG-QQD 1529

Query: 2326 GTYLATEVNPADTC 2339
            G Y       A TC
Sbjct: 1530 GIY-GCHAQGAATC 1542



 Score =  166 bits (421), Expect = 2e-40
 Identities = 201/852 (23%), Positives = 319/852 (37%), Gaps = 161/852 (18%)

Query: 314  MDTCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSDGS------V 367
            M TC+++ ++  C     D  F       +    + +   K  +V VF    S      V
Sbjct: 1561 MGTCTYV-LTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKV 1619

Query: 368  LLNELQVNLPHVTASFSV-FRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQ 426
            +LN  +V LP   A   V  R SS  +++    G++++   + +++  VT+  +  GQ+ 
Sbjct: 1620 MLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVE--VTVPSSYGGQLC 1677

Query: 427  GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAE 486
            GLCGN+N    DD       +          WK   S       +    S + +  + A+
Sbjct: 1678 GLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPS-SCQENSMAD 1736

Query: 487  HW---CSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAK 543
             W   C++L   + PF +CH  V P   +  C +  C  + +   LC +L +YA  C   
Sbjct: 1737 AWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQA 1796

Query: 544  GVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCP 602
            G     WR    C      CP    +    + C  TC S++           P D   CP
Sbjct: 1797 G-QAPAWRNRTFCPM---RCPPGSSYSPCSSPCPDTCSSINN----------PRD---CP 1839

Query: 603  DHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLHCRQIRLIGQSCTA 662
                     + +P A                     E C C+ G +      L G SC  
Sbjct: 1840 ---------KALPCA---------------------ESCECQKGHI------LSGTSCV- 1862

Query: 663  PKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECP 722
            P     C++                  AG YH         P G        C   + C 
Sbjct: 1863 PLGQCGCTD-----------------PAGSYH---------PVGERWYTENTCT--RLCT 1894

Query: 723  C-VHNNDLYSSGAKIKVDCNTCTCKRGRWVC--------TQAVCHGTCSIYGSGHYITFD 773
            C VHNN          + C   TCK  + +C         +A   G C + G  HY++FD
Sbjct: 1895 CSVHNN----------ITCFQSTCKPNQ-ICWALDGLLRCRASGVGVCQLPGESHYVSFD 1943

Query: 774  GKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPC-GTTGVTCSKAIKIFMGRTELKL 832
            G  +     C+ V V+  C    +L  F I  ++    G T       + I +   ++ L
Sbjct: 1944 GSNHSIPDACTLVLVK-VCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTL 2002

Query: 833  EDKHRVVIQRDE------GHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYK 886
            +  HRV+I   +            + +    Y +V    G+ V +D    + I++  +Y 
Sbjct: 2003 QKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYY 2062

Query: 887  GTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDV-----------S 932
            G VCG+CGNF+    ++       V +S+ +F NSWK+    P+C  +            
Sbjct: 2063 GKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQ 2122

Query: 933  TNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECF 992
             NP         R   EK  + L++ V++ C S++D  PF   C   +  C+ GG  +  
Sbjct: 2123 ENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCA--NTLCEFGGLYQAL 2180

Query: 993  CSAVASYAQECTKEG-ACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTING 1051
            C A+ ++   C  +G     WR    CP+ C  Y+        Y  C      +C  ++G
Sbjct: 2181 CQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYS-------SYTNCLPSCSPSCWDLDG 2233

Query: 1052 IHSNISV--SYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTH---YPPGASVPTE 1106
                  V  +  EGC   C   +P Y     KCV   +CGC  +D H    P G S  + 
Sbjct: 2234 RCEGAKVPSACAEGCI--C---QPGYVLSEDKCVPRSQCGC--KDAHGGSIPLGKSWVSS 2286

Query: 1107 ETCKSCVCTNSS 1118
               + CVCT  +
Sbjct: 2287 GCTEKCVCTGGA 2298



 Score =  165 bits (417), Expect = 6e-40
 Identities = 126/477 (26%), Positives = 199/477 (41%), Gaps = 79/477 (16%)

Query: 697  CVSGCVCPDG-LMDDGRGGCVVEKECPCVHNNDLYSSGAK---------------IKVDC 740
            C  GCVC  G L  D    C+    C C +NND Y  GA+                +V+C
Sbjct: 1070 CREGCVCNPGFLFSDNH--CIQASSCNCFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVEC 1127

Query: 741  N--------TCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYC 792
                      C  K G++ C       TC +YG  HY+TFDG+++ F G C+Y+  Q  C
Sbjct: 1128 QISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C 1186

Query: 793  GQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTT 852
            G NS+   F +  +N   G  GV+C   + + +  + + L    R ++   +    A  +
Sbjct: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPS 1245

Query: 853  REV-----GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTR 907
            + V     G+++ +++  G+ V WD    +++ ++ +Y G +CGLCGN+D  S+ND    
Sbjct: 1246 KGVFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305

Query: 908  DHMVVSSELDFGNSWK----EAPTCPDVS-TNPEPCSLNPHRRSWAEKQCSILKSS--VF 960
            D      + + GNSW+    E   C      N   C  +          C  L  +   F
Sbjct: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPF 1365

Query: 961  SICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCP 1019
              C   V    F+++C+ D C     G     C+ +++    C   G  V  WR P  CP
Sbjct: 1366 ETCLLHVKAASFFDSCMLDMCGFQ--GLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCP 1423

Query: 1020 IFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKD---RPIYE 1076
            + C    PP+     Y  C     +TC      HS  S  +   C  RC +     P + 
Sbjct: 1424 MAC----PPNS---KYSLCAKPCPDTC------HSGFSGMF---CSDRCVEACECNPGFV 1467

Query: 1077 EDLKKCVTADKCGCY--------VEDTHYPPGASVPTEETCKS-CVCTNSSQVVCRP 1124
                +C+   +CGC         V +  Y PG        CK  CVC +++++ C+P
Sbjct: 1468 LSGLECIPRSQCGCLHPAGSYFKVGERWYKPG--------CKELCVCESNNRIRCQP 1516



 Score =  164 bits (414), Expect = 1e-39
 Identities = 139/497 (27%), Positives = 206/497 (41%), Gaps = 81/497 (16%)

Query: 678  SKPRALSCQTLAAGYYHTE-CVSGCVCPDGLMDDGRGGCVVEKECPCVH--------NND 728
            +KP   +C +  +G + ++ CV  C C  G +  G   C+   +C C+H           
Sbjct: 1436 AKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLE-CIPRSQCGCLHPAGSYFKVGER 1494

Query: 729  LYSSGAKIKVDC---NTCTCK----RGRWVCTQAV----CHG----TCSIYGSGHYITFD 773
             Y  G K    C   N   C+    R +  C Q      CH     TC+  G  HY+TFD
Sbjct: 1495 WYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFD 1554

Query: 774  GKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCG-TTGVTCSKAIKIFMGRTELKL 832
            G  + F G C+YV  +  C   S    F +   N   G    V+  KA+ + +    + L
Sbjct: 1555 GALHHFMGTCTYVLTRP-CWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISL 1613

Query: 833  EDKHRVVIQRDEGHHVAY---------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAP 883
                +V++    GH VA          T R     +++ ++ G+ V +D    V + +  
Sbjct: 1614 LRGCKVMLN---GHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPS 1670

Query: 884  SYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK----EAPTCPDVSTNPEPCS 939
            SY G +CGLCGN+++ S +D    D  +    +  G +WK      P C  V   P  C 
Sbjct: 1671 SYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQ 1730

Query: 940  LNPHRRSWAEKQCSIL--KSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVA 997
             N    +W  K C+IL      FS CH  V P+  + +CVH  C   T GD    C ++ 
Sbjct: 1731 ENSMADAW-NKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCG--TKGDTTALCRSLQ 1787

Query: 998  SYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNIS 1057
            +YA  C + G    WR    CP+ C    PP      Y PC +   +TC +IN       
Sbjct: 1788 AYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSPCPDTCSSINN------ 1834

Query: 1058 VSYLEGCYPR-CPKDRPIYEE-DLKK--------CVTADKCGCY-VEDTHYPPGASVPTE 1106
                    PR CPK  P  E  + +K        CV   +CGC     +++P G    TE
Sbjct: 1835 --------PRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTE 1886

Query: 1107 ETC-KSCVCTNSSQVVC 1122
             TC + C C+  + + C
Sbjct: 1887 NTCTRLCTCSVHNNITC 1903



 Score =  133 bits (335), Expect = 2e-30
 Identities = 161/709 (22%), Positives = 256/709 (36%), Gaps = 132/709 (18%)

Query: 359  VVFKSDGSVLLNELQVNLPHVTASFSV-FRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTL 417
            V  +    VL+N  QV LP ++    V  + SS + +V++ IGV  QV+      L + +
Sbjct: 2000 VTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGV--QVKFDGNHLLEIEI 2057

Query: 418  DQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS---SCHDKL------ 468
                 G+V G+CGNFN  E D+    S  V  + + F N+WK +    SC   L      
Sbjct: 2058 PTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQI 2117

Query: 469  --DWLDDPCSLNIESANY--AEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQN 524
              +  ++P S N  +A+   A   C    +    + +C S +D   +   C    C    
Sbjct: 2118 PAEQQENP-SGNCRAADLRRAREKCEAALRAPV-WAQCASRIDLTPFLVDCANTLCEFGG 2175

Query: 525  NEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE 584
                LC AL ++   C ++G+    WR                                 
Sbjct: 2176 LYQALCQALQAFGATCQSQGLKPPLWRN-------------------------------- 2203

Query: 585  ADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCR 644
                    F P++   CP ++       C+P    SC+      E   V     E C+C+
Sbjct: 2204 ------SSFCPLE---CPAYSSYTN---CLPSCSPSCWDLDGRCEGAKVPSACAEGCICQ 2251

Query: 645  DGRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCP 704
             G +       + +    P+    C +  A   S P       L   +  + C   CVC 
Sbjct: 2252 PGYV-------LSEDKCVPRSQCGCKD--AHGGSIP-------LGKSWVSSGCTEKCVCT 2295

Query: 705  DGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIY 764
             G +  G   C     C    +N             + C   +             CS+Y
Sbjct: 2296 GGAIQCGDFRCPSGSHCQLTSDNSN-----------SNCVSDKSE----------QCSVY 2334

Query: 765  GSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITEN-VPCGTTGVTCSKAIKI 823
            G   Y+TFDG  Y   G  +YV ++        +    +   N +    + +   + I  
Sbjct: 2335 GDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITT 2394

Query: 824  FMG---RTELKLE---DKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTV 877
              G   + +  LE   +  ++ +      H+  T    GQ L + +   ++V +  R   
Sbjct: 2395 VYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLW--GQRLYLVTDFELVVSFGGRKNA 2452

Query: 878  FIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSW------------KEA 925
             I L   Y+G V GLCGN+D    ND       +  +   FGNSW            +  
Sbjct: 2453 VISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAI 2512

Query: 926  PTCPD-------VSTNPEPCSLNPHR-RSWAEKQCSIL--KSSVFSICHSKVDPKPFYEA 975
            P   +       + T  +    +P +  S + + C +L      F+ CH  V P+PF E 
Sbjct: 2513 PAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEH 2572

Query: 976  CVHDSCSC-DTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCPIFC 1022
            CV D CS  D     E  C  ++ YA  C + GA +  WR   LC   C
Sbjct: 2573 CVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621



 Score =  128 bits (321), Expect = 9e-29
 Identities = 119/455 (26%), Positives = 172/455 (37%), Gaps = 52/455 (11%)

Query: 1883 ETWWLCDCF-MATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYC 1941
            E W+   C  +  C+ NN +      C         +G+         GC  H +    C
Sbjct: 1493 ERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIY--------GC--HAQGAATC 1542

Query: 1942 TGWGDPHYVTFDGLYYSYQGNCTYVLVEEI-SPSVDN-FGVYIDNYHCDPNDKVSCPRTL 1999
            T  GDPHY+TFDG  + + G CTYVL     S S D+ F V   N +     +VS     
Sbjct: 1543 TASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVS----- 1597

Query: 2000 IVRHETQEVLIKTVHMMPMQV--------QVQVNRQAVALP-YKKYGLEVYQSGINYVVD 2050
                      IK VH+    +        +V +N   VALP +   G    +   N V+ 
Sbjct: 1598 ---------YIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLL 1648

Query: 2051 IPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQ 2110
                G+ V Y+G           +G    G CG   N + DD + P  ++  +       
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708

Query: 2111 WLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPP 2170
            W + + S+P C        +P+           +K+C       +     F+QCH +VPP
Sbjct: 1709 WKLPESSEPGC---FLVGGKPSSCQENSMADAWNKNCA----ILINPQGPFSQCHQVVPP 1761

Query: 2171 QHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQNICLDWRNHTHGACLVECPSHREYQ 2229
            Q  + +CV   C   G +   C SLQAYA+LCAQ      WRN T   C + CP    Y 
Sbjct: 1762 QSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTF--CPMRCPPGSSYS 1819

Query: 2230 ACGPAEEPTCKSSSSQQN---NTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPRE 2286
             C      TC S ++ ++        E C C +G +       V +  CGC  P      
Sbjct: 1820 PCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSC-VPLGQCGCTDPAGSYHP 1878

Query: 2287 FGEHF--EFDCKNCVCLEGGSGIICQPKRCSQKPV 2319
             GE +  E  C         + I C    C    +
Sbjct: 1879 VGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQI 1913



 Score =  111 bits (277), Expect = 1e-23
 Identities = 144/566 (25%), Positives = 198/566 (34%), Gaps = 67/566 (11%)

Query: 1326 PTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 1382
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533

Query: 1383 TPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1442
             P+     + P    + T    +T +T   T++        + P+   +TT     P   
Sbjct: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590

Query: 1443 PT-GTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAIT 1501
            PT  T+ PT   I+T     P+  P       T P    T +T  PT    +   P+   
Sbjct: 591  PTIPTEKPT---ISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKP 647

Query: 1502 TTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQT-PTPTPISTTT--TVTPTPTP 1558
            T +T  PT     T+ PT+    TTT++     PT   + PT  P   T   T++   T 
Sbjct: 648  TISTEKPT---VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETI 704

Query: 1559 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTT 1618
              T+ PT +P   T    PT  PT     +T+     TT T  PT  + K T      TT
Sbjct: 705  ISTEKPTISPEKPTI---PTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT 761

Query: 1619 TTVTATPTPTGTQTPTMIP-ISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPE 1677
             T   T +P     PT  P I T     PT  PT  +  P T T    I+    S P  +
Sbjct: 762  PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEK 821

Query: 1678 SSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTT-- 1735
             + P    +TS   T  +T   T+P      ST  P+ PT   T S      P    T  
Sbjct: 822  PTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIP 881

Query: 1736 TSPPGTPTRGTTTGSSSAPTPS---TVQTTTTSAWTPTPT-PLSTPSIIRTTGLRPYPSS 1791
            T  P  P   TT  +     P+   T+     +  T  PT P   P+I            
Sbjct: 882  TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTI------------ 929

Query: 1792 VLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTP 1851
                         P EE    T           L+   E    S      PT  P+ ST 
Sbjct: 930  -------------PTEETTISTE---------KLTIPTEKPTISPEKLTIPTEKPTISTE 967

Query: 1852 TPSKPSST----PSKPTPGTKPPECP 1873
             P+ P+        KPT  T+ P  P
Sbjct: 968  KPTIPTEKLTIPTEKPTIPTEKPTIP 993



 Score =  105 bits (261), Expect = 8e-22
 Identities = 96/343 (27%), Positives = 136/343 (39%), Gaps = 42/343 (12%)

Query: 28   RTRNHGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGS-----YKEFAVHLKRGP 82
            R R  G  VC   G  HY +FDG     P  C       C  +     +K  A H K   
Sbjct: 1922 RCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKE-E 1980

Query: 83   GQAEAPAGVESILLTIKDDTIYLTR-HLAVLNGAVVSTPHYS--PGLLIEKSDAYTKVYS 139
            G  EA   +  + + I D  + L + H  ++N   V+ P  S  PG+ ++ S  Y+ V  
Sbjct: 1981 GGTEA-FRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI 2039

Query: 140  RAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL-SDGVLFSPLEFGNMQK 198
            + G+ + ++    L +E+ T +    CG+CG++N  +     + SD V  S  EF N  K
Sbjct: 2040 KIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWK 2099

Query: 199  INQPDVVCED--PEEEVAPASCSEH-------------RAECERLLTAEAFADCQDLVPL 243
                D  C+    +E+  PA   E+             R +CE  L A  +A C   + L
Sbjct: 2100 DKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDL 2159

Query: 244  EPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGN 303
             P+L  C    C   G    +C  +  F   C   G +P  WR      S      CP  
Sbjct: 2160 TPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRN-----SSFCPLECPAY 2214

Query: 304  LVY---LESGSP-CMD---TCSHLEVSSLCEEHRMDGCFCPEG 339
              Y   L S SP C D    C   +V S C E    GC C  G
Sbjct: 2215 SSYTNCLPSCSPSCWDLDGRCEGAKVPSACAE----GCICQPG 2253



 Score =  103 bits (258), Expect = 2e-21
 Identities = 83/322 (25%), Positives = 130/322 (40%), Gaps = 23/322 (7%)

Query: 33   GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEF-AVHLKRGPGQAEAPAGV 91
            G   C  +G+ HY TFDG  F F G C Y  A  C  S   F  V  K      E  + +
Sbjct: 1152 GTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCL 1211

Query: 92   ESILLTIKDDTIYLTR-HLAVLNGAVVSTPHY-SPGLLIEKSDAYTKVYSRAGLTLMWNR 149
              + +T+ + T+ L +    ++ G  V+ P   S G+ +  S  + ++ +  GL + W+ 
Sbjct: 1212 SKVYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDG 1271

Query: 150  EDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL----EFGNMQKINQ-PDV 204
            +  L + + + +    CGLCG+Y+G         DG   SP     E GN  + +Q  D 
Sbjct: 1272 DQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDG---SPAGDKEELGNSWQTDQDEDQ 1328

Query: 205  VCEDPEEEVAPASCSEHRAE------CERLL-TAEAFADCQDLVPLEPYLRACQQDRCRC 257
             C+  +   +P+  S  ++       C RL+ T   F  C   V    +  +C  D C  
Sbjct: 1329 ECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGF 1388

Query: 258  PGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTC 317
             G    +C+ ++  +  C  AG     WR             CP N  Y     PC DTC
Sbjct: 1389 QGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHF-----CPMACPPNSKYSLCAKPCPDTC 1443

Query: 318  SHLEVSSLCEEHRMDGCFCPEG 339
                    C +  ++ C C  G
Sbjct: 1444 HSGFSGMFCSDRCVEACECNPG 1465



 Score =  102 bits (255), Expect = 4e-21
 Identities = 90/358 (25%), Positives = 145/358 (40%), Gaps = 31/358 (8%)

Query: 312  PCMD-TCSHLEVSSLCEEHRMDGCFCPEGAQADLPKTVVLLADKKKNVVVFKSDGSVLLN 370
            PC + T     V++  EE   +G  C       LP++ V L   ++ +V           
Sbjct: 1185 PCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTLV----------G 1234

Query: 371  ELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCG 430
              QV LP + +       S   + +    G+R  V+     QL+VT+     G++ GLCG
Sbjct: 1235 GQQVTLPAIPSKGVFLGASGRFVELQTEFGLR--VRWDGDQQLYVTVSSTYSGKLCGLCG 1292

Query: 431  NFNGLEGDDFKTASGLVEATGAGFANTWKAQSS----CHDKLDWLDDP-CSLNIESANYA 485
            N++G   +D     G          N+W+        C  K   ++ P C  +++S+   
Sbjct: 1293 NYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQ-KYQVVNSPSCDSSLQSSMSG 1351

Query: 486  EHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGV 545
              +C  L  T  PF  C   V  A ++  C  D C  Q  +  LC  +S+    C   G 
Sbjct: 1352 PGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGH 1411

Query: 546  MLWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDH 604
             +  WRE H C     +CP +  +      C  TC S   +   C +    V+ C C + 
Sbjct: 1412 AVKPWREPHFCPM---ACPPNSKYSLCAKPCPDTCHS-GFSGMFCSD--RCVEACEC-NP 1464

Query: 605  TFLDEKGRCVPLAKCSCYH-RGLYLEAGDVVVRQ--EERCVCR-DGRLHCRQIRLIGQ 658
             F+     C+P ++C C H  G Y + G+   +   +E CVC  + R+ C+  R   Q
Sbjct: 1465 GFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQ 1522



 Score =  100 bits (250), Expect = 1e-20
 Identities = 113/488 (23%), Positives = 184/488 (37%), Gaps = 68/488 (13%)

Query: 1892 MATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVT 1951
            + TC  +N +   +  C+P  +    +GL   R      C             G+ HYV+
Sbjct: 1892 LCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLP----------GESHYVS 1941

Query: 1952 FDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIK 2011
            FDG  +S    CT VLV+   P++      I   H    +K          HE    +  
Sbjct: 1942 FDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKH----EKEEGGTEAFRLHEVYIDIYD 1997

Query: 2012 TVHMMPMQVQVQVNRQAVALPYKKY--GLEVYQSGINYVVDIPELGVLVSYNGLS-FSVR 2068
                +    +V +N + V LP      G+ V  S I  +V+I ++GV V ++G     + 
Sbjct: 1998 AQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYSIVNI-KIGVQVKFDGNHLLEIE 2056

Query: 2069 LPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTT 2128
            +P   +G    G CG   +   D+ ++PS E+ ++     + W   D   P C       
Sbjct: 2057 IPTTYYG-KVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD-IDPSCQSLLVDE 2114

Query: 2129 KRPAVTVPGGGKTTPHKDCTPSPL------CQ-LIKDSLFAQCHALVPPQHYYDACVFDS 2181
            ++    +P   +  P  +C  + L      C+  ++  ++AQC + +    +   C    
Sbjct: 2115 QQ----IPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTL 2170

Query: 2182 CFMPG-SSLECASLQAYAALCAQQNICLD-WRNHTHGACLVECPSHREYQACGPAEEPTC 2239
            C   G     C +LQA+ A C  Q +    WRN +   C +ECP++  Y  C P+  P+C
Sbjct: 2171 CEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSF--CPLECPAYSSYTNCLPSCSPSC 2228

Query: 2240 KSSSSQQNN----TVLVEGCFCPEGTMNYAPGFDVCV--KTCGCVGPDNVPREFGEHFEF 2293
                 +       +   EGC C  G   Y    D CV    CGC          G+ +  
Sbjct: 2229 WDLDGRCEGAKVPSACAEGCICQPG---YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVS 2285

Query: 2294 D--CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCCNITVCKCNTSL 2351
                + CVC   G  I C   RC                    P+ + C +T    N++ 
Sbjct: 2286 SGCTEKCVCT--GGAIQCGDFRC--------------------PSGSHCQLTSDNSNSNC 2323

Query: 2352 CKEKPSVC 2359
              +K   C
Sbjct: 2324 VSDKSEQC 2331



 Score = 99.4 bits (246), Expect = 4e-20
 Identities = 132/524 (25%), Positives = 186/524 (35%), Gaps = 77/524 (14%)

Query: 1372 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTST---PITTTTTVTPTPTPTGTQTPTT 1428
            P P   +  +  P    T+VT    P+G Q P       I  + T +          P T
Sbjct: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQLIFKGIQGSNTASVVAMGFILINPGT 533

Query: 1429 TPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1488
             P+     + P    + T     T +T   T++        + P+   +TT     P   
Sbjct: 534  CPVKVLPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPS---VTTEKPTVPKEK 590

Query: 1489 PTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPIST 1548
            PT   T  PT  T   T+ P+  P       + P    T +T  PT    +   P+   T
Sbjct: 591  PT-IPTEKPTISTEKPTI-PSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPT 648

Query: 1549 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTK 1608
             +T  PT     T+ PTT    TTT++     PT  + P+   I T     PT  PT   
Sbjct: 649  ISTEKPT---VPTEEPTTPTEETTTSMEEPVIPT--EKPS---IPTEKPSIPTEKPT--- 697

Query: 1609 STTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAE 1668
                  I+   T+ +T  PT +     IP    T  T   T +      PT   T P  +
Sbjct: 698  ------ISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEK 751

Query: 1669 LTTSNPPPESSTPQTSRSTSSPL-----TESTTLLS---TLPPAIEMTSTAPPSTPTAPT 1720
             T S   PE  T  T + T SP      TE  T+ +   T+P      ST  P+TPT  T
Sbjct: 752  PTIS---PEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEET 808

Query: 1721 TTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSII 1780
            T S     +  PS     P  PT  TTT         +V+ TT S    T  P+  P+I 
Sbjct: 809  TIS-----TEKPSIPMEKPTLPTEETTT---------SVEETTISTEKLT-IPMEKPTIS 853

Query: 1781 RTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTP 1840
                  P         +  +    P E++                  T+     + P   
Sbjct: 854  TEKPTIPTEKPT----ISPEKLTIPTEKL------------------TIPTEKPTIPIEE 891

Query: 1841 SPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENET 1884
            +   T   + PT  KP+ +P KPT  T+ P  P   P     ET
Sbjct: 892  TTISTEKLTIPT-EKPTISPEKPTISTEKPTIPTEKPTIPTEET 934



 Score = 95.1 bits (235), Expect = 8e-19
 Identities = 80/294 (27%), Positives = 126/294 (42%), Gaps = 29/294 (9%)

Query: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000
            C+ +GDP Y+TFDG  Y  QG  TYVL++    +VD     ++    +  +K+  PR+ I
Sbjct: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIK----TVDVLPEGVEPLLVEGRNKMDPPRSSI 2386

Query: 2001 VRHETQEVLIKTVHMMPMQVQ----VQVNRQAVALPYK-KYGLEVYQSGINYVVDIPELG 2055
               E    +I TV+   +Q+Q    + VN Q +A+PY+    L V   G    + + +  
Sbjct: 2387 FLQE----VITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYL-VTDFE 2441

Query: 2056 VLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLV-N 2114
            ++VS+ G   +V      +     G CG       +D +LPSG +  N     + W V  
Sbjct: 2442 LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKT 2501

Query: 2115 DPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL-------CQLIKD--SLFAQCH 2165
            + +    P +    +       G        +C+P  L       C+++ D    FA CH
Sbjct: 2502 EDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACH 2561

Query: 2166 ALVPPQHYYDACVFDSCFMPG----SSLECASLQAYAALCAQQNICL-DWRNHT 2214
              V P+ + + CV D C          L C  L  YA LC +    L  WR+ T
Sbjct: 2562 QTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRT 2615



 Score = 94.0 bits (232), Expect = 2e-18
 Identities = 82/327 (25%), Positives = 132/327 (40%), Gaps = 31/327 (9%)

Query: 33   GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVH-LKRGPGQAEAPA 89
            G   C+  G+ HY TFDG +  F G C Y     C  R     F V       G     +
Sbjct: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVS 1597

Query: 90   GVESILLTIKDDTIYLTRHLAV-LNGAVVSTPHY--SPGLLIEKSDAYTKVYSRAGLTLM 146
             ++++ +T+ D +I L R   V LNG  V+ P +     + I  S     +Y+  GL + 
Sbjct: 1598 YIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657

Query: 147  WNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVC 206
            ++    + + + + +    CGLCG+YN     +  L D +       G+  ++     + 
Sbjct: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYN-----NNSLDDNLRPDRKLAGDSMQLGAAWKLP 1712

Query: 207  EDPEEEV-----APASCSEH------RAECERLLTAEA-FADCQDLVPLEPYLRACQQDR 254
            E  E         P+SC E+         C  L+  +  F+ C  +VP +    +C   +
Sbjct: 1713 ESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQ 1772

Query: 255  CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCM 314
            C   G  T +C ++  ++  C+ AG  P  WR  T          CP    Y    SPC 
Sbjct: 1773 CGTKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTF-----CPMRCPPGSSYSPCSSPCP 1826

Query: 315  DTCSHLEVSSLCEEHR--MDGCFCPEG 339
            DTCS +     C +     + C C +G
Sbjct: 1827 DTCSSINNPRDCPKALPCAESCECQKG 1853



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 99/375 (26%), Positives = 134/375 (35%), Gaps = 75/375 (20%)

Query: 1556 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPI 1615
            P P   +  +  P    T+VT    P+G Q P   LI      + T +  +     + P 
Sbjct: 477  PIPLWKRVGSQRPYWQNTSVT---VPSGHQQPMQ-LIFKGIQGSNTASVVAMGFILINPG 532

Query: 1616 TTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAEL-----T 1670
            T        P     + P + P+S+T      P+ TTG T  PT ++  P   +     T
Sbjct: 533  TC-------PVKVLPELPPVSPVSSTG-----PSETTGLTENPTISTKKPTVSIEKPSVT 580

Query: 1671 TSNP--PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTA----PTTTSG 1724
            T  P  P E  T  T + T S  TE  T+ S  P       T P   PT     PT  S 
Sbjct: 581  TEKPTVPKEKPTIPTEKPTIS--TEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSE 638

Query: 1725 GHTL-SPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTT 1783
              T+ S  P+ +T  P  PT   TT     PT    + TTTS   P   P   PSI    
Sbjct: 639  KPTIPSEKPTISTEKPTVPTEEPTT-----PT----EETTTSMEEPV-IPTEKPSI---- 684

Query: 1784 GLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPT 1843
                                 P E+    T   T       +S      +   P+ P+  
Sbjct: 685  ---------------------PTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEK 723

Query: 1844 PT--PSKSTPTPSKPSSTPSKPT-PGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNT 1900
            PT    KST +P KP++   KPT P  KP   P+      E  T       ++  K    
Sbjct: 724  PTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPT-------ISPEKLTIP 776

Query: 1901 VEIVKVECEPPPMPT 1915
             E   +  E P +PT
Sbjct: 777  TEKPTIPTEKPTIPT 791



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 71/328 (21%), Positives = 117/328 (35%), Gaps = 36/328 (10%)

Query: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAG---VES 93
            CS +G+  Y TFDG  +R  G   Y          +     L  G  + + P     ++ 
Sbjct: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390

Query: 94   ILLTIKDDTIYLTRHLA-VLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWN---R 149
            ++ T+    + L   L  V+N   ++ P Y P   +  +    ++Y      L+ +   R
Sbjct: 2391 VITTVYGYKVQLQAGLELVVNNQKMAVP-YRPNEHLRVTLWGQRLYLVTDFELVVSFGGR 2449

Query: 150  EDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVVCED 208
            ++A+ + L + +     GLCG+Y+  +     L  G L   L  FGN  ++   D +   
Sbjct: 2450 KNAV-ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508

Query: 209  PE---------------------EEVAPASCSEHRAECERLLTAEA--FADCQDLVPLEP 245
            P                       E +P   + +  +  R+L      FA C   V  EP
Sbjct: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEP 2568

Query: 246  YLRACQQDRCRCPGG---DTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPG 302
            +   C  D C        +   C  ++ ++  C  AG     WR  T   SP     C  
Sbjct: 2569 FQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNPCQN 2628

Query: 303  NLVYLESGSPCMDTCSHLEVSSLCEEHR 330
            +    E G+     C       LC E R
Sbjct: 2629 DGQCREQGATFTCECEVGYGGGLCMEPR 2656


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 134,047,297
Number of Sequences: 37866
Number of extensions: 8319731
Number of successful extensions: 223404
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 554
Number of HSP's successfully gapped in prelim test: 1477
Number of HSP's that attempted gapping in prelim test: 42774
Number of HSP's gapped (non-prelim): 43266
length of query: 2639
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2520
effective length of database: 13,741,464
effective search space: 34628489280
effective search space used: 34628489280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press