Guide to the Human Genome
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Search of human proteins with 117938316

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117938316 tripartite motif-containing 22 [Homo sapiens]
         (498 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117938316 tripartite motif-containing 22 [Homo sapiens]           1018   0.0  
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]      618   e-177
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]      618   e-177
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...   618   e-177
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    547   e-156
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    547   e-156
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s...   521   e-148
gi|15208660 tripartite motif protein 21 [Homo sapiens]                357   1e-98
gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s...   354   1e-97
gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s...   354   1e-97
gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]     321   1e-87
gi|18641343 tripartite motif protein 34 isoform 2 [Homo sapiens]      315   8e-86
gi|37622899 ring finger protein 137 [Homo sapiens]                    287   2e-77
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            260   2e-69
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              247   2e-65
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             237   2e-62
gi|5730009 ret finger protein [Homo sapiens]                          236   3e-62
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   233   4e-61
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   219   6e-57
gi|22749269 ring finger protein 129 [Homo sapiens]                    211   1e-54
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   194   2e-49
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    194   2e-49
gi|169202375 PREDICTED: tripartite motif-containing protein 64B-...   194   2e-49
gi|210147600 tripartite motif-containing 64 [Homo sapiens]            194   2e-49
gi|239755486 PREDICTED: tripartite motif-containing protein 64C-...   184   2e-46
gi|239750044 PREDICTED: tripartite motif-containing protein 64C-...   184   2e-46
gi|239744355 PREDICTED: tripartite motif-containing protein 64C-...   184   2e-46
gi|20270353 tripartite motif-containing 43 [Homo sapiens]             179   7e-45
gi|239755484 PREDICTED: tripartite motif-containing protein 64C-...   178   9e-45
gi|239750042 PREDICTED: tripartite motif-containing protein 64C-...   178   9e-45

>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
          Length = 498

 Score = 1018 bits (2633), Expect = 0.0
 Identities = 498/498 (100%), Positives = 498/498 (100%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ
Sbjct: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
           TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE
Sbjct: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120

Query: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
           LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER
Sbjct: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180

Query: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
           QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR
Sbjct: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240

Query: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300
           LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW
Sbjct: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300

Query: 301 VDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWEVD 360
           VDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWEVD
Sbjct: 301 VDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWEVD 360

Query: 361 VSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNA 420
           VSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNA
Sbjct: 361 VSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNA 420

Query: 421 FEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYP 480
           FEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYP
Sbjct: 421 FEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYP 480

Query: 481 YFNPWNCLVPMTVCPPSS 498
           YFNPWNCLVPMTVCPPSS
Sbjct: 481 YFNPWNCLVPMTVCPPSS 498


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  618 bits (1594), Expect = e-177
 Identities = 303/498 (60%), Positives = 376/498 (75%), Gaps = 10/498 (2%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           M   + +++++EVTCPICLELLTEPLSLDCGHS C+ACIT   KE+V    G+SSCPVC 
Sbjct: 1   MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
             +   +L+ N+HLANIVER+KEVK+SP  G+KRD+C+HHG+KL +FCKED KVICW+CE
Sbjct: 61  ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120

Query: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
            SQEH+GH T    EV KECQEKLQ  L+RL KE++EAEKLE DIR+E+T+WK  +Q ER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180

Query: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
           Q+I   F+++R IL+NEEQRELQ+LEE E   LD  A A D+LVQQ+Q    LISD++ R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240

Query: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300
            + S++E+LQD+  +MK SE W LKKPK VSKKLK+VF  PDLS MLQ+ +ELT V+ YW
Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300

Query: 301 VDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWEVD 360
           VDV LN  +   N+ +S DQRQV +V    F+  N      +GV G QYFSSGK+YWEVD
Sbjct: 301 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYN------YGVLGSQYFSSGKHYWEVD 354

Query: 361 VSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNA 420
           VS K AWILGV+ +  S + +    +      N   +Y++YRP +GYWVIGLQN C+Y  
Sbjct: 355 VSKKTAWILGVYCRTYSRHMK----YVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGV 410

Query: 421 FEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYP 480
           FE+S SSDP+VLTL MAVPPCR+GVFLDYEAGIVSFFNVT+HG+LIYKFS C FS+P YP
Sbjct: 411 FEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYP 470

Query: 481 YFNPWNCLVPMTVCPPSS 498
           YFNPWNC  PMT+CPPSS
Sbjct: 471 YFNPWNCPAPMTLCPPSS 488


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  618 bits (1594), Expect = e-177
 Identities = 303/498 (60%), Positives = 376/498 (75%), Gaps = 10/498 (2%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           M   + +++++EVTCPICLELLTEPLSLDCGHS C+ACIT   KE+V    G+SSCPVC 
Sbjct: 1   MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
             +   +L+ N+HLANIVER+KEVK+SP  G+KRD+C+HHG+KL +FCKED KVICW+CE
Sbjct: 61  ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120

Query: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
            SQEH+GH T    EV KECQEKLQ  L+RL KE++EAEKLE DIR+E+T+WK  +Q ER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180

Query: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
           Q+I   F+++R IL+NEEQRELQ+LEE E   LD  A A D+LVQQ+Q    LISD++ R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240

Query: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300
            + S++E+LQD+  +MK SE W LKKPK VSKKLK+VF  PDLS MLQ+ +ELT V+ YW
Sbjct: 241 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 300

Query: 301 VDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWEVD 360
           VDV LN  +   N+ +S DQRQV +V    F+  N      +GV G QYFSSGK+YWEVD
Sbjct: 301 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYN------YGVLGSQYFSSGKHYWEVD 354

Query: 361 VSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNA 420
           VS K AWILGV+ +  S + +    +      N   +Y++YRP +GYWVIGLQN C+Y  
Sbjct: 355 VSKKTAWILGVYCRTYSRHMK----YVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGV 410

Query: 421 FEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYP 480
           FE+S SSDP+VLTL MAVPPCR+GVFLDYEAGIVSFFNVT+HG+LIYKFS C FS+P YP
Sbjct: 411 FEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYP 470

Query: 481 YFNPWNCLVPMTVCPPSS 498
           YFNPWNC  PMT+CPPSS
Sbjct: 471 YFNPWNCPAPMTLCPPSS 488


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score =  618 bits (1594), Expect = e-177
 Identities = 303/498 (60%), Positives = 376/498 (75%), Gaps = 10/498 (2%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           M   + +++++EVTCPICLELLTEPLSLDCGHS C+ACIT   KE+V    G+SSCPVC 
Sbjct: 355 MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 414

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
             +   +L+ N+HLANIVER+KEVK+SP  G+KRD+C+HHG+KL +FCKED KVICW+CE
Sbjct: 415 ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 474

Query: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
            SQEH+GH T    EV KECQEKLQ  L+RL KE++EAEKLE DIR+E+T+WK  +Q ER
Sbjct: 475 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 534

Query: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
           Q+I   F+++R IL+NEEQRELQ+LEE E   LD  A A D+LVQQ+Q    LISD++ R
Sbjct: 535 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 594

Query: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300
            + S++E+LQD+  +MK SE W LKKPK VSKKLK+VF  PDLS MLQ+ +ELT V+ YW
Sbjct: 595 SQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYW 654

Query: 301 VDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWEVD 360
           VDV LN  +   N+ +S DQRQV +V    F+  N      +GV G QYFSSGK+YWEVD
Sbjct: 655 VDVTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYN------YGVLGSQYFSSGKHYWEVD 708

Query: 361 VSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNA 420
           VS K AWILGV+ +  S + +    +      N   +Y++YRP +GYWVIGLQN C+Y  
Sbjct: 709 VSKKTAWILGVYCRTYSRHMK----YVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGV 764

Query: 421 FEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYP 480
           FE+S SSDP+VLTL MAVPPCR+GVFLDYEAGIVSFFNVT+HG+LIYKFS C FS+P YP
Sbjct: 765 FEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYP 824

Query: 481 YFNPWNCLVPMTVCPPSS 498
           YFNPWNC  PMT+CPPSS
Sbjct: 825 YFNPWNCPAPMTLCPPSS 842



 Score =  369 bits (946), Expect = e-102
 Identities = 181/300 (60%), Positives = 228/300 (76%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           M   V VDI +EVTCPICLELLTEPLS+DCGHSFCQACIT   +ESVI   GE SCPVCQ
Sbjct: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
           T +QPGNLRPNRHLANIV R++EV + P +  K  +C  HG+KLQ+FC+EDGKVICW+CE
Sbjct: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148

Query: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
            SQEH+GH TF + EV +E QEK Q +L++L  E+QEAEKL   IR+++T+WKN ++ ER
Sbjct: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208

Query: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
            +I   FN++R ILD  EQREL+KLE+ E   L  +  A + LV Q Q    LISDL+RR
Sbjct: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268

Query: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300
            +GS++E+LQDV DV +RSE WTL+KP+++  KL+S+FR PDL  ML+V +ELTDVQ YW
Sbjct: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  547 bits (1409), Expect = e-156
 Identities = 287/501 (57%), Positives = 355/501 (70%), Gaps = 16/501 (3%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           M   V VDI +EVTCPICLELLTEPLS+DCGHSFCQACIT   +ESVI   GE SCPVCQ
Sbjct: 1   MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 60

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
           T +QPGNLRPNRHLANIV R++EV + P +  K  +C  HG+KLQ+FC+EDGKVICW+CE
Sbjct: 61  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120

Query: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
            SQEH+GH TF + EV +E QEK Q +L++L  E+QEAEKL   IR+++T+WKN ++ ER
Sbjct: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180

Query: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
            +I   FN++R ILD  EQREL+KLE+ E   L  +  A + LV Q Q    LISDL+RR
Sbjct: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 240

Query: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300
            +GS++E+LQDV DV +RSE WTL+KP+++  KL+S+FR PDL  ML+V +ELTDVQ YW
Sbjct: 241 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 300

Query: 301 VDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAF---GVFGCQYFSSGKYYW 357
           VDV LNP +A  N+ ++ ++RQV+ V     K S P          V G Q+FSSGK+YW
Sbjct: 301 VDVTLNPHTANLNLVLAKNRRQVRFVGA---KVSGPSCLEKHYDCSVLGSQHFSSGKHYW 357

Query: 358 EVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCE 417
           EVDV+ K AWILGV S  +SL       F+F+        YSRY+PQ GYWVIGLQ+  E
Sbjct: 358 EVDVAKKTAWILGVCS--NSLGPT----FSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHE 411

Query: 418 YNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRP 477
           Y A+EDSS S    L L M VPP R+GVFLDYEAG VSF+NVTNHG  IY FS   F   
Sbjct: 412 YRAYEDSSPS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTT 467

Query: 478 AYPYFNPWNCLVPMTVCPPSS 498
             PYFNP NC++PMT+  PSS
Sbjct: 468 LCPYFNPCNCVIPMTLRRPSS 488


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  547 bits (1409), Expect = e-156
 Identities = 287/501 (57%), Positives = 355/501 (70%), Gaps = 16/501 (3%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           M   V VDI +EVTCPICLELLTEPLS+DCGHSFCQACIT   +ESVI   GE SCPVCQ
Sbjct: 29  MTSPVLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQ 88

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
           T +QPGNLRPNRHLANIV R++EV + P +  K  +C  HG+KLQ+FC+EDGKVICW+CE
Sbjct: 89  TSYQPGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148

Query: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
            SQEH+GH TF + EV +E QEK Q +L++L  E+QEAEKL   IR+++T+WKN ++ ER
Sbjct: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208

Query: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
            +I   FN++R ILD  EQREL+KLE+ E   L  +  A + LV Q Q    LISDL+RR
Sbjct: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERR 268

Query: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300
            +GS++E+LQDV DV +RSE WTL+KP+++  KL+S+FR PDL  ML+V +ELTDVQ YW
Sbjct: 269 CQGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYW 328

Query: 301 VDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAF---GVFGCQYFSSGKYYW 357
           VDV LNP +A  N+ ++ ++RQV+ V     K S P          V G Q+FSSGK+YW
Sbjct: 329 VDVTLNPHTANLNLVLAKNRRQVRFVGA---KVSGPSCLEKHYDCSVLGSQHFSSGKHYW 385

Query: 358 EVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCE 417
           EVDV+ K AWILGV S  +SL       F+F+        YSRY+PQ GYWVIGLQ+  E
Sbjct: 386 EVDVAKKTAWILGVCS--NSLGPT----FSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHE 439

Query: 418 YNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRP 477
           Y A+EDSS S    L L M VPP R+GVFLDYEAG VSF+NVTNHG  IY FS   F   
Sbjct: 440 YRAYEDSSPS----LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTT 495

Query: 478 AYPYFNPWNCLVPMTVCPPSS 498
             PYFNP NC++PMT+  PSS
Sbjct: 496 LCPYFNPCNCVIPMTLRRPSS 516


>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
           sapiens]
          Length = 493

 Score =  521 bits (1343), Expect = e-148
 Identities = 273/512 (53%), Positives = 355/512 (69%), Gaps = 33/512 (6%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           M   + V++++EVTCPICLELLT+PLSLDCGHSFCQAC+TA  K+S++  +GESSCPVC+
Sbjct: 1   MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
             +QP N+RPNRH+AN+VE+++EVK+SP EGQK D C  HG+KL +FC+EDGKVICW+CE
Sbjct: 60  ISYQPENIRPNRHVANLVEKLREVKLSP-EGQKVDHCARHGEKLLLFCQEDGKVICWLCE 118

Query: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
            SQEH+GH TF   EV +E Q KLQ AL+ L ++ QEAE+LE DIR+E+ +WK  IQ ++
Sbjct: 119 RSQEHRGHHTFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178

Query: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
             +L  F ++R ILD EE  ELQ LE+ E ++L +L  +  ++VQQ Q    LISDL+ R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238

Query: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300
           L+GS +E+LQ V  V+KR+E+ TLKKP++  K  + VFR PDL GML+V +ELTDV+ YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298

Query: 301 VDVMLNPGSATSNVAISVDQRQVKT-----------VRTCTFKNSNPCDFSAFGVFGCQY 349
           VDV + P + +  V IS D+RQV +            R  TF N N C     G+ G Q 
Sbjct: 299 VDVTVAPNNISCAV-ISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCT----GILGSQS 353

Query: 350 FSSGKYYWEVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWV 409
            +SGK+YWEVDVS K AWILGV            +GF  D   N  K    Y+P+YGYWV
Sbjct: 354 ITSGKHYWEVDVSKKTAWILGV-----------CAGFQPDAMCNIEK-NENYQPKYGYWV 401

Query: 410 IGLQNTCEYNAFEDSS---SSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALI 466
           IGL+   + +AF+DSS    S P ++ L + + P R+GVFLDYEA  VSFFN+TNHG LI
Sbjct: 402 IGLEEGVKCSAFQDSSFHTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLI 461

Query: 467 YKFSGCRFSRPAYPYFNPWNCLVPMTVCPPSS 498
           YKFS C FS+P +PY NP  C VPMT+C PSS
Sbjct: 462 YKFSHCSFSQPVFPYLNPRKCGVPMTLCSPSS 493


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  357 bits (916), Expect = 1e-98
 Identities = 203/491 (41%), Positives = 286/491 (58%), Gaps = 44/491 (8%)

Query: 11  KEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNLRP 70
           +EVTCPICL+   EP+S++CGHSFCQ CI      S +   G S CPVC+ RF   NLRP
Sbjct: 12  EEVTCPICLDPFVEPVSIECGHSFCQECI------SQVGKGGGSVCPVCRQRFLLKNLRP 65

Query: 71  NRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQEHQGHQT 130
           NR LAN+V  +KE+    +EG + + C  HG++L +FC++DGK +CWVC  S++H+ H  
Sbjct: 66  NRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAM 125

Query: 131 FRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKILKGFNEM 190
             + E  +E QEKLQVAL  L ++ + AEKLE +I  +R  WK  ++ ++ +I   F + 
Sbjct: 126 VPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQ 185

Query: 191 RVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRGSSVEMLQ 250
           +  L  EEQR+LQ+LE+ E   L  L     +L QQ Q    LIS+L RR   S++E+LQ
Sbjct: 186 KNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQ 245

Query: 251 DVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYWVDVMLNPGSA 310
           +VI V++RSESW LK     S +L+SV  VP L  ML+            V + L+P +A
Sbjct: 246 EVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCA---------VHITLDPDTA 296

Query: 311 TSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFG-VFGCQYFSSGKYYWEVDVSGKIAWIL 369
              + +S D+RQV+   T      N   F ++  V G Q+F SGK+YWEVDV+GK AW L
Sbjct: 297 NPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDL 356

Query: 370 GVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNAFEDSSSSDP 429
           GV       + R+   F                 + G+W I L N  +Y A      + P
Sbjct: 357 GVCRD----SVRRKGHFLLS-------------SKSGFWTIWLWNKQKYEA-----GTYP 394

Query: 430 KVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYPYFNP----- 484
           +   L + VPPC++G+FLDYEAG+VSF+N+T+HG+LIY FS C F+ P  P+F+P     
Sbjct: 395 QT-PLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDG 453

Query: 485 WNCLVPMTVCP 495
                P+T+CP
Sbjct: 454 GKNTAPLTLCP 464


>gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo
           sapiens]
          Length = 326

 Score =  354 bits (908), Expect = 1e-97
 Identities = 172/300 (57%), Positives = 229/300 (76%), Gaps = 2/300 (0%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           M   + V++++EVTCPICLELLT+PLSLDCGHSFCQAC+TA  K+S++  +GESSCPVC+
Sbjct: 1   MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
             +QP N+RPNRH+ANIVE+++EVK+SP EGQK D C  HG+KL +FC+EDGKVICW+CE
Sbjct: 60  ISYQPENIRPNRHVANIVEKLREVKLSP-EGQKVDHCARHGEKLLLFCQEDGKVICWLCE 118

Query: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
            SQEH+GH TF   EV +E Q KLQ AL+ L ++ QEAE+LE DIR+E+ +WK  IQ ++
Sbjct: 119 RSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178

Query: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
             +L  F ++R ILD EE  ELQ LE+ E ++L +L  +  ++VQQ Q    LISDL+ R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238

Query: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300
           L+GS +E+LQ V  V+KR+E+ TLKKP++  K  + VFR PDL GML+V +ELTDV+ YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298


>gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo
           sapiens]
          Length = 347

 Score =  354 bits (908), Expect = 1e-97
 Identities = 172/300 (57%), Positives = 229/300 (76%), Gaps = 2/300 (0%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           M   + V++++EVTCPICLELLT+PLSLDCGHSFCQAC+TA  K+S++  +GESSCPVC+
Sbjct: 1   MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSML-DKGESSCPVCR 59

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
             +QP N+RPNRH+ANIVE+++EVK+SP EGQK D C  HG+KL +FC+EDGKVICW+CE
Sbjct: 60  ISYQPENIRPNRHVANIVEKLREVKLSP-EGQKVDHCARHGEKLLLFCQEDGKVICWLCE 118

Query: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
            SQEH+GH TF   EV +E Q KLQ AL+ L ++ QEAE+LE DIR+E+ +WK  IQ ++
Sbjct: 119 RSQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDK 178

Query: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
             +L  F ++R ILD EE  ELQ LE+ E ++L +L  +  ++VQQ Q    LISDL+ R
Sbjct: 179 TNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHR 238

Query: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300
           L+GS +E+LQ V  V+KR+E+ TLKKP++  K  + VFR PDL GML+V +ELTDV+ YW
Sbjct: 239 LQGSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYW 298


>gi|145275183 tripartite motif protein 34 isoform 3 [Homo sapiens]
          Length = 270

 Score =  321 bits (822), Expect = 1e-87
 Identities = 154/257 (59%), Positives = 199/257 (77%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           M   + +++++EVTCPICLELLTEPLSLDCGHS C+ACIT   KE+V    G+SSCPVC 
Sbjct: 1   MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
             +   +L+ N+HLANIVER+KEVK+SP  G+KRD+C+HHG+KL +FCKED KVICW+CE
Sbjct: 61  ISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCE 120

Query: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
            SQEH+GH T    EV KECQEKLQ  L+RL KE++EAEKLE DIR+E+T+WK  +Q ER
Sbjct: 121 RSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTER 180

Query: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
           Q+I   F+++R IL+NEEQRELQ+LEE E   LD  A A D+LVQQ+Q    LISD++ R
Sbjct: 181 QRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECR 240

Query: 241 LRGSSVEMLQDVIDVMK 257
            + S++E+LQD+  +MK
Sbjct: 241 SQWSTMELLQDMSGIMK 257


>gi|18641343 tripartite motif protein 34 isoform 2 [Homo sapiens]
          Length = 243

 Score =  315 bits (806), Expect = 8e-86
 Identities = 155/253 (61%), Positives = 187/253 (73%), Gaps = 10/253 (3%)

Query: 246 VEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYWVDVML 305
           +E+LQD+  +MK SE W LKKPK VSKKLK+VF  PDLS MLQ+ +ELT V+ YWVDV L
Sbjct: 1   MELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTL 60

Query: 306 NPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWEVDVSGKI 365
           N  +   N+ +S DQRQV +V    F+  N      +GV G QYFSSGK+YWEVDVS K 
Sbjct: 61  NSVNLNLNLVLSEDQRQVISVPIWPFQCYN------YGVLGSQYFSSGKHYWEVDVSKKT 114

Query: 366 AWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNAFEDSS 425
           AWILGV+ +  S + +    +      N   +Y++YRP +GYWVIGLQN C+Y  FE+S 
Sbjct: 115 AWILGVYCRTYSRHMK----YVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESL 170

Query: 426 SSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYPYFNPW 485
           SSDP+VLTL MAVPPCR+GVFLDYEAGIVSFFNVT+HG+LIYKFS C FS+P YPYFNPW
Sbjct: 171 SSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPW 230

Query: 486 NCLVPMTVCPPSS 498
           NC  PMT+CPPSS
Sbjct: 231 NCPAPMTLCPPSS 243


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  287 bits (734), Expect = 2e-77
 Identities = 175/502 (34%), Positives = 268/502 (53%), Gaps = 48/502 (9%)

Query: 9   IEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNL 68
           I +EV CPIC+  L EP+S+DCGHSFC +C++   +          +CP+C+   QP NL
Sbjct: 10  IVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQPRNL 69

Query: 69  RPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQEHQGH 128
           RPN  LAN+VE+V+ +++ P  G K D+CE HG+KL++FCKED  ++C  C  S EH+ H
Sbjct: 70  RPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPEHEAH 129

Query: 129 QTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKILKGFN 188
               + +V  E + +L  AL+ L KE +EA KLE   R+    WK  ++  +Q I+  F 
Sbjct: 130 SVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVWEFE 189

Query: 189 EMRVILDN----------EEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQ 238
           + + +L+           E    L  L+      +  L     +L+QQ Q    +I++L+
Sbjct: 190 KYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRMIAELK 249

Query: 239 RRLRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQY 298
            R +     MLQD+ +V+ RS+SW+L++P+ +S +LK+  RV    G+ ++LK       
Sbjct: 250 ERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRV---LGLREILKT------ 300

Query: 299 YWVDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFG-VFGCQYFSSGKYYW 357
           Y  DV L+P +A S + +S D+++V    T      NP  F  +  V G Q  SSG++YW
Sbjct: 301 YAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQCISSGRHYW 360

Query: 358 EVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCE 417
           EV+V  +  W LGV  +                +V+  +V     P YG+WVI L+   E
Sbjct: 361 EVEVGDRSEWGLGVCKQ----------------NVDRKEVV-YLSPHYGFWVIRLRKGNE 403

Query: 418 YNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRP 477
           Y A  D      +   L + VPP R+G+F+DYEA  +SF+NVT+ G+ I+ F    F   
Sbjct: 404 YRAGTD------EYPILSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGR 457

Query: 478 AYPYFNP-----WNCLVPMTVC 494
             PYF+P      N   P+ +C
Sbjct: 458 LLPYFSPCYSIGTNNTAPLAIC 479


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  260 bits (664), Expect = 2e-69
 Identities = 165/491 (33%), Positives = 262/491 (53%), Gaps = 39/491 (7%)

Query: 9   IEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNL 68
           + ++  CP+CL+ L EP+S+DCGHSFC  CI+   ++S     G  +CP C+  F+P   
Sbjct: 10  LREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGF 69

Query: 69  RPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQEHQGH 128
           RPNR LA +VE V+ + +    G +R  C  HG+ L  FC+ED   +CWVC+   EH+ H
Sbjct: 70  RPNRQLAGLVESVRRLGLGAGPGARR--CARHGEDLSRFCEEDEAALCWVCDAGPEHRTH 127

Query: 129 QTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKILKGFN 188
           +T  + E     Q KLQ+AL+ + KE ++A   E ++ ++   WK  ++++RQ+    F 
Sbjct: 128 RTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFE 187

Query: 189 EMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRGSSVEM 248
           + R  L  EEQR+L++LE  E   L  L  +  +LVQQ +    L  +LQ R +  ++ +
Sbjct: 188 KHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRPALGL 247

Query: 249 LQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYWVDVMLNPG 308
           L+ V  V+ RS++ T  + +++  +LK+   +P   G  ++L++      + VDV L+P 
Sbjct: 248 LEGVRGVLSRSKAVTRLEAENIPMELKTACCIP---GRRELLRK------FQVDVKLDPA 298

Query: 309 SATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFG-VFGCQYFSSGKYYWEVDVSGKIAW 367
           +A  ++ ++ D R V+         +NP  F  +  + G Q FSSG++YWEV V     W
Sbjct: 299 TAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSGRHYWEVLVGEGAEW 358

Query: 368 ILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNAFEDSSSS 427
            LGV     +L ++  +     PS           P+ G W + L    EY        +
Sbjct: 359 GLGVCQ--DTLPRKGET----TPS-----------PENGVWALWLLKGNEYMVL-----A 396

Query: 428 DPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYPYFNPWNC 487
            P V  L +  P C IG+FLDYEAG +SF+NVT+ G+ IY F+   FS    PYF  + C
Sbjct: 397 SPSVPLLQLESPRC-IGIFLDYEAGEISFYNVTD-GSYIYTFNQL-FSGLLRPYF--FIC 451

Query: 488 LVPMTVCPPSS 498
                + PP++
Sbjct: 452 DATPLILPPTT 462


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  247 bits (631), Expect = 2e-65
 Identities = 159/489 (32%), Positives = 252/489 (51%), Gaps = 40/489 (8%)

Query: 11  KEVTCPICLELLTEPLSLDCGHSFCQACITAKIKE--SVIISRGESSCPVCQTRFQPGNL 68
           +E TC ICL L+T P+S++CGHS+C  CIT   K      + +    CP C+  F   +L
Sbjct: 12  EEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMDSL 71

Query: 69  RPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQEHQGH 128
           RPN+ L +++E +KE             CE HG++  +FC+++G++ICW CE + +H+GH
Sbjct: 72  RPNKQLGSLIEALKETDQEMS-------CEEHGEQFHLFCEDEGQLICWRCERAPQHKGH 124

Query: 129 QTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKILKGFN 188
            T  + +V +  +EKLQ A+ +L + +    + +       T WK  +QI+RQKI   F 
Sbjct: 125 TTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDFK 184

Query: 189 EMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRGSSVEM 248
            ++  L  EE+  L +LE+ E   L  L      L  +  +  + I +L+ + +GS+ ++
Sbjct: 185 NLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQKL 244

Query: 249 LQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYWVDVMLNPG 308
           LQ+V D + RS +  L+  ++VS +L ++  V  L     V K L   Q   V V L+P 
Sbjct: 245 LQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKL--YFDVKKMLRSHQ---VSVTLDPD 299

Query: 309 SATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFG-VFGCQYFSSGKYYWEVDVSGKIAW 367
           +A   + +S D+RQV    T   ++++   F+AF  V GC+ F+SG+ Y+EVDV     W
Sbjct: 300 TAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGW 359

Query: 368 ILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNAFEDSSSS 427
            LGV  +    N ++ +G              +  PQ G+W + L     Y A     +S
Sbjct: 360 DLGVCME----NVQRGTGM-------------KQEPQSGFWTLRLCKKKGYVALTSPPTS 402

Query: 428 DPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYPYFNPWNC 487
                 L +   P  +G+FLDYEAG+VSF+N  N G  I+ F    FS    PYF  +  
Sbjct: 403 ------LHLHEQPLLVGIFLDYEAGVVSFYN-GNTGCHIFTFPKASFSDTLRPYFQVYQ- 454

Query: 488 LVPMTVCPP 496
             P+ + PP
Sbjct: 455 YSPLFLPPP 463


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  237 bits (604), Expect = 2e-62
 Identities = 149/494 (30%), Positives = 258/494 (52%), Gaps = 44/494 (8%)

Query: 5   VKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQ 64
           +  ++++E TC ICL+  T+P+  DCGH+FC+ CI     +      G  +CP C+    
Sbjct: 6   LSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP----EGPYACPECRELSP 61

Query: 65  PGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQE 124
             NLRPNR LA + E  +  ++ P     + VC  H + L  FC ++ +++C  CE S E
Sbjct: 62  QRNLRPNRPLAKMAEMAR--RLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGE 119

Query: 125 HQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKIL 184
           H  H+   + +  ++ + KL+ +L+ L K+ Q+A   +    +    W+  ++ +RQ +L
Sbjct: 120 HWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVL 179

Query: 185 KGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRGS 244
             F  +R +L  EEQ+ LQ+LEE E+ VL  L      L QQ    + LI++L+ R +  
Sbjct: 180 GEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLP 239

Query: 245 SVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYWVDVM 304
           ++ +LQD+ D ++R +   L+ P+ V  +L++V RVP   G+++ L+          DV 
Sbjct: 240 ALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVP---GLVETLRRFRG------DVT 290

Query: 305 LNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFG-VFGCQYFSSGKYYWEVDVSG 363
           L+P +A   + +S D+R V+          +P  F     V G + F+SG++YWEV+V  
Sbjct: 291 LDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGD 350

Query: 364 KIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNAFED 423
           + +W LGV  +  ++N+++    +                  G+W++    +  YN+ E 
Sbjct: 351 RTSWALGVCRE--NVNRKEKGELS---------------AGNGFWILVFLGS-YYNSSER 392

Query: 424 SSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYPYFN 483
           + +         +  PP R+G+FLDYEAG +SF++ T+ G+L++ F    FS    P F+
Sbjct: 393 ALAP--------LRDPPRRVGIFLDYEAGHLSFYSATD-GSLLFIFPEIPFSGTLRPLFS 443

Query: 484 PWNCL-VPMTVCPP 496
           P +    PMT+C P
Sbjct: 444 PLSSSPTPMTICRP 457


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  236 bits (603), Expect = 3e-62
 Identities = 159/517 (30%), Positives = 253/517 (48%), Gaps = 51/517 (9%)

Query: 4   SVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRF 63
           SV   +++E TCP+CL+   EP+ LDCGH+ C AC+          +    SCP C+  F
Sbjct: 5   SVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLA----RCWGTAETNVSCPQCRETF 60

Query: 64  QPGNLRPNRHLANIVERVKEVKMSPQEGQ--KRDVCEHHGKKLQIFCKEDGKVICWVCEL 121
              ++RPNRHLAN+ + VK+++     G   +  VCE H + L+++C+ED   IC VC+ 
Sbjct: 61  PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR 120

Query: 122 SQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQ 181
           S+EH+GH    + E V+  +E++Q  L  L +     ++      Q R    +  Q+ER+
Sbjct: 121 SREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMERE 180

Query: 182 KILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRL 241
           KI+  F ++   L   E R L +LEE ++ + +++  A  Q        S+LI+ L+ + 
Sbjct: 181 KIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQ 240

Query: 242 RGSSVEMLQDVIDVMKRSESWTLKK----PKSVSKKL-----KSVFRVPDLSGM------ 286
           +  + E+LQD+ D + R+E   + +    P  + +K+     K +F    L         
Sbjct: 241 QQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQS 300

Query: 287 -LQVLKELTDVQYYWVDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFG-V 344
            ++ ++EL + Q Y VDV L+P +A  ++ +S + RQV+          NP  F+ F  V
Sbjct: 301 DMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCV 360

Query: 345 FGCQYFSSGKYYWEVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQ 404
            G   F +G++YWEV+V  K  W +GV                 D       V S   PQ
Sbjct: 361 LGSPCFIAGRHYWEVEVGDKAKWTIGV---------------CEDSVCRKGGVTS--APQ 403

Query: 405 YGYWVIGLQNTCEYNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGA 464
            G+W + L    EY A     ++ P      +  P  R+G+FLDY+AG VSF+NVT    
Sbjct: 404 NGFWAVSLWYGKEYWALTSPMTALP------LRTPLQRVGIFLDYDAGEVSFYNVTER-C 456

Query: 465 LIYKFSGCRFSRPAYPYF----NPWNCLVPMTVCPPS 497
             + FS   F  P  PYF    +      P+ +CP S
Sbjct: 457 HTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMS 493


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  233 bits (593), Expect = 4e-61
 Identities = 152/499 (30%), Positives = 260/499 (52%), Gaps = 44/499 (8%)

Query: 8   DIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGN 67
           +++ E +C +CLE L EP+ ++CGH+FC+ACIT   ++       +  CPVC+   +  +
Sbjct: 22  NLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDL----ERDFPCPVCRKTSRYRS 77

Query: 68  LRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQEHQG 127
           LRPNR L ++VE  K+++   ++ +   +C  H + L +FC ED + +C +C +S  H+ 
Sbjct: 78  LRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRA 137

Query: 128 HQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKILKGF 187
           H    +++  +E +EKLQ  L+ L ++ QE  + +    ++    K  ++  RQ+IL+ F
Sbjct: 138 HTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREF 197

Query: 188 NEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRGSSVE 247
            E+   LD E+Q  L +LEE E ++L  L      L  +R+D + L ++++ +   S  E
Sbjct: 198 EELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFE 257

Query: 248 MLQDVIDVMKRSESWTLKKPKSVSKKLKSVFR--VPDLSGMLQVLKELTDVQYYWVDVML 305
           ML+DV   +++ E     +  SVS +L+  F         + ++LK+L        DV L
Sbjct: 258 MLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLI------ADVTL 311

Query: 306 NPGSATSNVAISVDQRQVKTVRT-CTFKNSNPCDFSAFG-VFGCQYFSSGKYYWEVDVSG 363
           +P +A  N+ +S D++ VK V T        P  F+ +  V   + F+SG++YWEV+V  
Sbjct: 312 DPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGD 371

Query: 364 KIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNAFED 423
           K  W +GV  + S   K + +                  P+ GYW + L N  +Y     
Sbjct: 372 KTHWAVGV-CRDSVSRKGELTPL----------------PETGYWRVRLWNGDKY----- 409

Query: 424 SSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYPYFN 483
            +++      L + V P R+G+FLDYEAG +SF+NVT+  + IY F+   F+   +P F 
Sbjct: 410 -AATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDR-SHIYTFTD-TFTEKLWPLFY 466

Query: 484 PW-----NCLVPMTVCPPS 497
           P          P+T+ PP+
Sbjct: 467 PGIRAGRKNAAPLTIRPPT 485


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  219 bits (557), Expect = 6e-57
 Identities = 151/523 (28%), Positives = 265/523 (50%), Gaps = 62/523 (11%)

Query: 8   DIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGN 67
           +++ E +C +CLE L EP+ ++CGH+FC+ACIT   ++       +  CPVC+   +  +
Sbjct: 22  NLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDL----ERDFPCPVCRKTSRYRS 77

Query: 68  LRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQEHQG 127
           LRPNR L ++VE  K+++   ++ +   +C  H + L +FC ED + +C +C +S  H+ 
Sbjct: 78  LRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRA 137

Query: 128 HQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKILKGF 187
           H    +++  +E +EKLQ  L+ L ++ QE  + +    ++    K  ++  RQ+IL+ F
Sbjct: 138 HTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREF 197

Query: 188 NEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRGSSVE 247
            E+   LD E+Q  L +LEE E ++L  L      L  +R+D + L ++++ +   S  E
Sbjct: 198 EELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFE 257

Query: 248 MLQDVIDVMKRS---------ESWTLKKPKSVSKKLKSVFRVPDLSGM------LQVLKE 292
           ML+DV   ++++          +   +  K++   +K + R   +  M      +++ K 
Sbjct: 258 MLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEVTSVSIELEKN 317

Query: 293 LTDV--QYYWV---------DVMLNPGSATSNVAISVDQRQVKTVRT-CTFKNSNPCDFS 340
            ++   QY+ +         DV L+P +A  N+ +S D++ VK V T        P  F+
Sbjct: 318 FSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFT 377

Query: 341 AFG-VFGCQYFSSGKYYWEVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYS 399
            +  V   + F+SG++YWEV+V  K  W +GV  + S   K + +               
Sbjct: 378 FYPCVLATEGFTSGRHYWEVEVGDKTHWAVGV-CRDSVSRKGELTPL------------- 423

Query: 400 RYRPQYGYWVIGLQNTCEYNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNV 459
              P+ GYW + L N  +Y A      +      L + V P R+G+FLDYEAG +SF+NV
Sbjct: 424 ---PETGYWRVRLWNGDKYAA------TTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNV 474

Query: 460 TNHGALIYKFSGCRFSRPAYPYFNPW-----NCLVPMTVCPPS 497
           T+  + IY F+   F+   +P F P          P+T+ PP+
Sbjct: 475 TDR-SHIYTFTD-TFTEKLWPLFYPGIRAGRKNAAPLTIRPPT 515


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  211 bits (537), Expect = 1e-54
 Identities = 156/503 (31%), Positives = 256/503 (50%), Gaps = 55/503 (10%)

Query: 7   VDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPG 66
           V++++E +CPICLE L +P++++CGH+FC++C++   K+          CPVC+  F   
Sbjct: 8   VNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKD----LDDTFPCPVCRFCFPYK 63

Query: 67  NLRPNRHLANIVERVK--EVKMSPQEGQKRD-VCEHHGKKLQIFCKEDGKVICWVCELSQ 123
           + R N  L N+ E  K  +++ S ++ QK + +CE H + L +FC +D +++C  C  S 
Sbjct: 64  SFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFST 123

Query: 124 EHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKI 183
           +HQ H    I +     +E L+ +L+ L    +  EK+      +    K  ++ +R++I
Sbjct: 124 KHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREEI 183

Query: 184 LKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRG 243
              F ++R+ L NE++  L+++++ E+N+   LA   + LV+     STL   L R + G
Sbjct: 184 NSEFEQIRLFLQNEQEMILRQIQDEEMNI---LAKLNENLVELSDYVSTL-KHLLREVEG 239

Query: 244 SSVEMLQDVIDVMK--RSESWTLKKPKSVSKKL-KSVFRV-PDLSGMLQVLKELTDVQYY 299
            SV+   +++   K    +   LK P+  S +L K  F + P  SG+ +++K       +
Sbjct: 240 KSVQSNLELLTQAKSMHHKYQNLKCPELFSFRLTKYGFSLPPQYSGLDRIIKP------F 293

Query: 300 WVDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPC-DFSAF----GVFGCQYFSSGK 354
            VDV+L+  +A   + +S D++ V+  R    K  N C D   F     V G Q FSSG+
Sbjct: 294 QVDVILDLNTAHPQLLVSEDRKAVRYER----KKRNICYDPRRFYVCPAVLGSQRFSSGR 349

Query: 355 YYWEVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQN 414
           +YWEV+V  K  WILGV       N      +   PSV             G+W IG   
Sbjct: 350 HYWEVEVGNKPKWILGVCQDCLLRN------WQDQPSV-----------LGGFWAIGRYM 392

Query: 415 TCEYNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRF 474
              Y A      S PK   L   V P +IG+FLDYE G +SF+N+ N  +++Y F+ C F
Sbjct: 393 KSGYVA------SGPKTTQLLPVVKPSKIGIFLDYELGDLSFYNM-NDRSILYTFNDC-F 444

Query: 475 SRPAYPYFNPWNCLVPMTVCPPS 497
           +   +PYF       P+ +C  S
Sbjct: 445 TEAVWPYFYTGTDSEPLKICSVS 467


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  194 bits (493), Expect = 2e-49
 Identities = 139/487 (28%), Positives = 238/487 (48%), Gaps = 53/487 (10%)

Query: 9   IEKEVTCPICLELLTEPLSLDCGHSFCQACIT-----AKIKESVIISRGESSCPVCQTRF 63
           +++E TC ICL+  T+P+   CGH+FC+ACI      A+ K+     +G   CP C+   
Sbjct: 10  LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMS 69

Query: 64  QPGNLRPNRHLANIVERVKEVKMSPQEG-QKRDVCEHHGKKLQIFCKEDGKVICWVCELS 122
              NL PNR L  + E  ++       G QK+D+C+ H + L++FC++D   IC VC  S
Sbjct: 70  PQRNLLPNRLLTKVAEMAQQ-----HPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRES 124

Query: 123 QEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQK 182
           +EH+ H+     E V+  + KL+  ++ L ++      L+    Q    W+  ++  R++
Sbjct: 125 REHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRER 184

Query: 183 ILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLR 242
           I+  F +M + L  EEQR LQ LE  E      L  +   L +Q      L+  L+ R  
Sbjct: 185 IVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERST 244

Query: 243 GSSVEMLQDVIDVMKRSESWTLKKPK-SVSKKLKSVFRVPDLSGMLQVLKELTDVQYYWV 301
              ++MLQD+ + + R  + +++ P+ +   + ++V RVP   G ++VL+   +      
Sbjct: 245 QGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVP---GQIEVLRGFLE------ 295

Query: 302 DVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQY----FSSGKYYW 357
           DV+ +  SA   + +  + RQ + + +   + S  C    F  + C      FSSG++YW
Sbjct: 296 DVVPDATSAYPYLLL-YESRQRRYLGSSP-EGSGFCSKDRFVAYPCAVGQTAFSSGRHYW 353

Query: 358 EV--DVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNT 415
           EV  +++G   W LGV     S   R                     P+ G+WV+ L   
Sbjct: 354 EVGMNITGDALWALGVCRDNVSRKDRVPK-----------------CPENGFWVVQLSKG 396

Query: 416 CEYNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFS 475
            +Y       S+   +  + +  PP  +G+FLD+EAG VSF++V++ G+ ++ +S   F 
Sbjct: 397 TKY------LSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSD-GSHLHTYSQATFP 449

Query: 476 RPAYPYF 482
            P  P+F
Sbjct: 450 GPLQPFF 456


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  194 bits (493), Expect = 2e-49
 Identities = 139/487 (28%), Positives = 238/487 (48%), Gaps = 53/487 (10%)

Query: 9   IEKEVTCPICLELLTEPLSLDCGHSFCQACIT-----AKIKESVIISRGESSCPVCQTRF 63
           +++E TC ICL+  T+P+   CGH+FC+ACI      A+ K+     +G   CP C+   
Sbjct: 10  LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMS 69

Query: 64  QPGNLRPNRHLANIVERVKEVKMSPQEG-QKRDVCEHHGKKLQIFCKEDGKVICWVCELS 122
              NL PNR L  + E  ++       G QK+D+C+ H + L++FC++D   IC VC  S
Sbjct: 70  PQRNLLPNRLLTKVAEMAQQ-----HPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRES 124

Query: 123 QEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQK 182
           +EH+ H+     E V+  + KL+  ++ L ++      L+    Q    W+  ++  R++
Sbjct: 125 REHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRER 184

Query: 183 ILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLR 242
           I+  F +M + L  EEQR LQ LE  E      L  +   L +Q      L+  L+ R  
Sbjct: 185 IVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERST 244

Query: 243 GSSVEMLQDVIDVMKRSESWTLKKPK-SVSKKLKSVFRVPDLSGMLQVLKELTDVQYYWV 301
              ++MLQD+ + + R  + +++ P+ +   + ++V RVP   G ++VL+   +      
Sbjct: 245 QGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVP---GQIEVLRGFLE------ 295

Query: 302 DVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQY----FSSGKYYW 357
           DV+ +  SA   + +  + RQ + + +   + S  C    F  + C      FSSG++YW
Sbjct: 296 DVVPDATSAYPYLLL-YESRQRRYLGSSP-EGSGFCSKDRFVAYPCAVGQTAFSSGRHYW 353

Query: 358 EV--DVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNT 415
           EV  +++G   W LGV     S   R                     P+ G+WV+ L   
Sbjct: 354 EVGMNITGDALWALGVCRDNVSRKDRVPK-----------------CPENGFWVVQLSKG 396

Query: 416 CEYNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFS 475
            +Y       S+   +  + +  PP  +G+FLD+EAG VSF++V++ G+ ++ +S   F 
Sbjct: 397 TKY------LSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSD-GSHLHTYSQATFP 449

Query: 476 RPAYPYF 482
            P  P+F
Sbjct: 450 GPLQPFF 456


>gi|169202375 PREDICTED: tripartite motif-containing protein
           64B-like [Homo sapiens]
          Length = 449

 Score =  194 bits (493), Expect = 2e-49
 Identities = 136/477 (28%), Positives = 226/477 (47%), Gaps = 46/477 (9%)

Query: 10  EKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNLR 69
           + E+ C IC+    +P+++DCGHSFC+ C+    +E     R    CP C+   +  N  
Sbjct: 10  QNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEG----RAPMRCPSCRKTSEKPNFN 65

Query: 70  PNRHLANIVERVKEVKMSPQEGQKRD-VCEHHGKKLQIFCKEDGKVICWVCELSQEHQGH 128
            N  L  +    ++ +  PQ     D +C  H +  ++FC+ D +++C  C  S EH  H
Sbjct: 66  TNLVLKKLSSLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEHMAH 123

Query: 129 QTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAW---KNYIQIERQKILK 185
               I    +EC+EKL   +  L + +QE     +++ QE + +   K+Y+ + ++ I  
Sbjct: 124 SHSPIGWAAEECREKLIKEMDYLWEINQETR---NNLNQETSTFHSLKDYVSVRKRIITI 180

Query: 186 GFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRGSS 245
            + +M + LD EEQR LQ LE     +   L  +  ++ Q  +    +  +L        
Sbjct: 181 QYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHMPD 240

Query: 246 VEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYWVDVML 305
           V +LQDV +V  R++   ++KP+ V+ +L S      ++G+L +L        + VD  L
Sbjct: 241 VVLLQDVRNVSARTDLAQMQKPQPVNPELTSWC----ITGVLDMLNN------FRVDSAL 290

Query: 306 NPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWEVDVSGKI 365
           +       +++S D R V          ++P    +F V+G Q F+SGK+YWEVDV+   
Sbjct: 291 STEMIPCYISLSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHYWEVDVTLSS 350

Query: 366 AWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNAFEDSS 425
            WILGV       ++   + F  D    +  + S+    Y                  S 
Sbjct: 351 NWILGVCRD----SRTADANFVIDSDERFFLISSKRSNHY------------------SL 388

Query: 426 SSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYPYF 482
           S++   L  ++  P  R+GVFLDY+ G VSFF+V+  G+LIY F    FS P  P+F
Sbjct: 389 STNSPPLIQYVQRPLGRVGVFLDYDNGSVSFFDVSK-GSLIYGFPPSSFSSPLRPFF 444


>gi|210147600 tripartite motif-containing 64 [Homo sapiens]
          Length = 449

 Score =  194 bits (492), Expect = 2e-49
 Identities = 134/474 (28%), Positives = 223/474 (47%), Gaps = 40/474 (8%)

Query: 10  EKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNLR 69
           + E+ C IC+    +P+++DCGHSFC+ C+    +E     R    CP C+   +  N  
Sbjct: 10  QNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEG----RAPMRCPSCRKISEKPNFN 65

Query: 70  PNRHLANIVERVKEVKMSPQEGQKRD-VCEHHGKKLQIFCKEDGKVICWVCELSQEHQGH 128
            N  L  +    ++ +  PQ     D +C  H +  ++FC+ D +++C  C  S EH  H
Sbjct: 66  TNVVLKKLSSLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEHMAH 123

Query: 129 QTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKILKGFN 188
               I    +EC+EKL   +  L + +QE     +   +   + K+Y+ + ++ I   + 
Sbjct: 124 SHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETRTFHSLKDYVSVRKRIITIQYQ 183

Query: 189 EMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRGSSVEM 248
           +M + LD EEQR LQ LE     +   L  +  ++ Q  +    +  +L        VE+
Sbjct: 184 KMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHVPDVEL 243

Query: 249 LQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYWVDVMLNPG 308
           LQDV +V  R++   ++KP+ V+ +L S      ++G+L +L        + VD  L+  
Sbjct: 244 LQDVRNVSARTDLAQMQKPQPVNPELTSWC----ITGVLDMLNN------FRVDSALSTE 293

Query: 309 SATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWEVDVSGKIAWI 368
                +++S D R V          ++P    +F V+G Q F+SGK+YWEVDV+    WI
Sbjct: 294 MIPCYISLSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHYWEVDVTLSSNWI 353

Query: 369 LGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNAFEDSSSSD 428
           LGV       ++   + F  D    +  + S+    Y                  S S++
Sbjct: 354 LGVCQD----SRTADANFVIDSDERFFLISSKRSNHY------------------SLSTN 391

Query: 429 PKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYPYF 482
              L  ++  P  ++GVFLDY+ G VSFF+V+  G+LIY F    FS P  P+F
Sbjct: 392 SPPLIQYVQRPLGQVGVFLDYDNGSVSFFDVSK-GSLIYGFPPSSFSSPLRPFF 444


>gi|239755486 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score =  184 bits (467), Expect = 2e-46
 Identities = 133/484 (27%), Positives = 225/484 (46%), Gaps = 44/484 (9%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           MD       + E+ C IC+    +P++ DC HSFC+ C+    +E     R    CP+C+
Sbjct: 1   MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEG----RAPMRCPLCR 56

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRD-VCEHHGKKLQIFCKEDGKVICWVC 119
              +  N   N  L  +    ++ +  PQ     D +C  H +  ++FC+ D +++C  C
Sbjct: 57  KISEKPNFNTNVALKKLASLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114

Query: 120 ELSQEHQGHQTFRINEVVKECQ-EKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQI 178
             S EH  H    I    +EC+ +KL   +  L K +QE +   +++ QE + + + ++ 
Sbjct: 115 SESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQ---NNLNQETSKFCSLVED 171

Query: 179 ERQKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQ 238
           +R +I+  + +M + LD EEQR LQ LE     +   L  +  ++ Q  +    +  +L 
Sbjct: 172 KRNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELW 231

Query: 239 RRLRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQY 298
                  VE+LQDV ++  R++   + KP+ V+ +L S      ++G+L +L        
Sbjct: 232 ETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTSWC----ITGVLDMLNN------ 281

Query: 299 YWVDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWE 358
           + VD  L+       +++S D R+V           +P    +F V+  Q F+SGK+YWE
Sbjct: 282 FRVDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPMDPQGVESFAVWCAQAFTSGKHYWE 341

Query: 359 VDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEY 418
           VDV+    WILGV       ++   +    D    +  + S+    Y             
Sbjct: 342 VDVTHSSNWILGVCRD----SRTADTNIVIDSDKTFFSISSKTSNHY------------- 384

Query: 419 NAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPA 478
                S S++   L  ++  P   +GVFLDY+ G VSFF+V+  G+LIY F    FS P 
Sbjct: 385 -----SLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSK-GSLIYGFPPSSFSSPL 438

Query: 479 YPYF 482
            P+F
Sbjct: 439 RPFF 442


>gi|239750044 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score =  184 bits (467), Expect = 2e-46
 Identities = 133/484 (27%), Positives = 225/484 (46%), Gaps = 44/484 (9%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           MD       + E+ C IC+    +P++ DC HSFC+ C+    +E     R    CP+C+
Sbjct: 1   MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEG----RAPMRCPLCR 56

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRD-VCEHHGKKLQIFCKEDGKVICWVC 119
              +  N   N  L  +    ++ +  PQ     D +C  H +  ++FC+ D +++C  C
Sbjct: 57  KISEKPNFNTNVALKKLASLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114

Query: 120 ELSQEHQGHQTFRINEVVKECQ-EKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQI 178
             S EH  H    I    +EC+ +KL   +  L K +QE +   +++ QE + + + ++ 
Sbjct: 115 SESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQ---NNLNQETSKFCSLVED 171

Query: 179 ERQKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQ 238
           +R +I+  + +M + LD EEQR LQ LE     +   L  +  ++ Q  +    +  +L 
Sbjct: 172 KRNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELW 231

Query: 239 RRLRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQY 298
                  VE+LQDV ++  R++   + KP+ V+ +L S      ++G+L +L        
Sbjct: 232 ETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTSWC----ITGVLDMLNN------ 281

Query: 299 YWVDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWE 358
           + VD  L+       +++S D R+V           +P    +F V+  Q F+SGK+YWE
Sbjct: 282 FRVDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPMDPQGVESFAVWCAQAFTSGKHYWE 341

Query: 359 VDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEY 418
           VDV+    WILGV       ++   +    D    +  + S+    Y             
Sbjct: 342 VDVTHSSNWILGVCRD----SRTADTNIVIDSDKTFFSISSKTSNHY------------- 384

Query: 419 NAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPA 478
                S S++   L  ++  P   +GVFLDY+ G VSFF+V+  G+LIY F    FS P 
Sbjct: 385 -----SLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSK-GSLIYGFPPSSFSSPL 438

Query: 479 YPYF 482
            P+F
Sbjct: 439 RPFF 442


>gi|239744355 PREDICTED: tripartite motif-containing protein
           64C-like isoform 1 [Homo sapiens]
          Length = 447

 Score =  184 bits (467), Expect = 2e-46
 Identities = 133/484 (27%), Positives = 225/484 (46%), Gaps = 44/484 (9%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           MD       + E+ C IC+    +P++ DC HSFC+ C+    +E     R    CP+C+
Sbjct: 1   MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEG----RAPMRCPLCR 56

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRD-VCEHHGKKLQIFCKEDGKVICWVC 119
              +  N   N  L  +    ++ +  PQ     D +C  H +  ++FC+ D +++C  C
Sbjct: 57  KISEKPNFNTNVALKKLASLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114

Query: 120 ELSQEHQGHQTFRINEVVKECQ-EKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQI 178
             S EH  H    I    +EC+ +KL   +  L K +QE +   +++ QE + + + ++ 
Sbjct: 115 SESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQ---NNLNQETSKFCSLVED 171

Query: 179 ERQKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQ 238
           +R +I+  + +M + LD EEQR LQ LE     +   L  +  ++ Q  +    +  +L 
Sbjct: 172 KRNRIVYRYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELW 231

Query: 239 RRLRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQY 298
                  VE+LQDV ++  R++   + KP+ V+ +L S      ++G+L +L        
Sbjct: 232 ETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTSWC----ITGVLDMLNN------ 281

Query: 299 YWVDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWE 358
           + VD  L+       +++S D R+V           +P    +F V+  Q F+SGK+YWE
Sbjct: 282 FRVDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPMDPQGVESFAVWCAQAFTSGKHYWE 341

Query: 359 VDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEY 418
           VDV+    WILGV       ++   +    D    +  + S+    Y             
Sbjct: 342 VDVTHSSNWILGVCRD----SRTADTNIVIDSDKTFFSISSKTSNHY------------- 384

Query: 419 NAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPA 478
                S S++   L  ++  P   +GVFLDY+ G VSFF+V+  G+LIY F    FS P 
Sbjct: 385 -----SLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSK-GSLIYGFPPSSFSSPL 438

Query: 479 YPYF 482
            P+F
Sbjct: 439 RPFF 442


>gi|20270353 tripartite motif-containing 43 [Homo sapiens]
          Length = 446

 Score =  179 bits (453), Expect = 7e-45
 Identities = 127/486 (26%), Positives = 231/486 (47%), Gaps = 49/486 (10%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           MD       +KE+TC ICL  L +P+++ CGHSFC+ C+    +E+    +  ++CP C+
Sbjct: 1   MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEA----QSPANCPACR 56

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCE 120
                 + + N  L N+V   ++  +      ++ +C  H +  ++FC  D  ++C +C 
Sbjct: 57  EPSPKMDFKTNILLKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCS 116

Query: 121 LSQEHQGHQTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER 180
            SQEH  H+   I E  +E +EKL   ++ L K+ QE ++   +  +    W+  + +  
Sbjct: 117 NSQEHGAHKHHPIEEAAEEHREKLLKQMRILWKKIQENQRNLYEEGRTAFLWRGNVVLRA 176

Query: 181 QKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR 240
           Q I   + ++  +L  EE++ L++L +    +   L  +  ++ Q+ +    +  +L   
Sbjct: 177 QMIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEM 236

Query: 241 LRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYW 300
                VE+LQD+ D++ RSES  L  P+ V+ +L +      ++G++  L        + 
Sbjct: 237 CHKPDVELLQDLGDIVARSESVLLHMPQPVNPELTA----GPITGLVYRLNR------FR 286

Query: 301 VDVMLNPGSATSNVAISVDQRQVKTVRTCTFK----NSNPCDFSAFGVFGCQYFSSGKYY 356
           V++  +      N+ +  D      VR+  F+    NS+  D+  F  +G + FS GK+Y
Sbjct: 287 VEISFHFEVTNHNIRLFED------VRSWMFRRGPLNSDRSDY--FAAWGARVFSFGKHY 338

Query: 357 WEVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTC 416
           WE+DV     W LGV +  S + K  +        VN   +         + ++ L+   
Sbjct: 339 WELDVDNSCDWALGVCNN-SWIRKNST-------MVNSEDI---------FLLLCLKVDN 381

Query: 417 EYNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSR 476
            +N    S      V   ++  P  R+GVFLD+E+G VSF NVT   +LI+ +     + 
Sbjct: 382 HFNLLTTS-----PVFPHYIEKPLGRVGVFLDFESGSVSFLNVTK-SSLIWSYPAGSLTF 435

Query: 477 PAYPYF 482
           P  P+F
Sbjct: 436 PVRPFF 441


>gi|239755484 PREDICTED: tripartite motif-containing protein
           64C-like isoform 1 [Homo sapiens]
          Length = 450

 Score =  178 bits (452), Expect = 9e-45
 Identities = 131/484 (27%), Positives = 219/484 (45%), Gaps = 41/484 (8%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           MD       + E+ C IC+    +P++ DC HSFC+ C+    +E     R    CP+C+
Sbjct: 1   MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEG----RAPMRCPLCR 56

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRD-VCEHHGKKLQIFCKEDGKVICWVC 119
              +  N   N  L  +    ++ +  PQ     D +C  H +  ++FC+ D +++C  C
Sbjct: 57  KISEKPNFNTNVALKKLASLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114

Query: 120 ELSQEHQGHQTFRINEVVKECQ-EKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQI 178
             S EH  H    I    +EC+ +KL   +  L K +QE +   +    +  +  +Y+ +
Sbjct: 115 SESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQNNLNQETSKFCSLVDYVSL 174

Query: 179 ERQKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQ 238
            +  I   + +M + LD EEQR LQ LE     +   L  +  ++ Q  +    +  +L 
Sbjct: 175 RKVIITIQYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELW 234

Query: 239 RRLRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQY 298
                  VE+LQDV ++  R++   + KP+ V+ +L S      ++G+L +L        
Sbjct: 235 ETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTSWC----ITGVLDMLNN------ 284

Query: 299 YWVDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWE 358
           + VD  L+       +++S D R+V           +P    +F V+  Q F+SGK+YWE
Sbjct: 285 FRVDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPMDPQGVESFAVWCAQAFTSGKHYWE 344

Query: 359 VDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEY 418
           VDV+    WILGV       ++   +    D    +  + S+    Y             
Sbjct: 345 VDVTHSSNWILGVCRD----SRTADTNIVIDSDKTFFSISSKTSNHY------------- 387

Query: 419 NAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPA 478
                S S++   L  ++  P   +GVFLDY+ G VSFF+V+  G+LIY F    FS P 
Sbjct: 388 -----SLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSK-GSLIYGFPPSSFSSPL 441

Query: 479 YPYF 482
            P+F
Sbjct: 442 RPFF 445


>gi|239750042 PREDICTED: tripartite motif-containing protein
           64C-like isoform 1 [Homo sapiens]
          Length = 450

 Score =  178 bits (452), Expect = 9e-45
 Identities = 131/484 (27%), Positives = 219/484 (45%), Gaps = 41/484 (8%)

Query: 1   MDFSVKVDIEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQ 60
           MD       + E+ C IC+    +P++ DC HSFC+ C+    +E     R    CP+C+
Sbjct: 1   MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEG----RAPMRCPLCR 56

Query: 61  TRFQPGNLRPNRHLANIVERVKEVKMSPQEGQKRD-VCEHHGKKLQIFCKEDGKVICWVC 119
              +  N   N  L  +    ++ +  PQ     D +C  H +  ++FC+ D +++C  C
Sbjct: 57  KISEKPNFNTNVALKKLASLARQTR--PQNINSSDNICVLHEETKELFCEADKRLLCGPC 114

Query: 120 ELSQEHQGHQTFRINEVVKECQ-EKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQI 178
             S EH  H    I    +EC+ +KL   +  L K +QE +   +    +  +  +Y+ +
Sbjct: 115 SESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQNNLNQETSKFCSLVDYVSL 174

Query: 179 ERQKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQ 238
            +  I   + +M + LD EEQR LQ LE     +   L  +  ++ Q  +    +  +L 
Sbjct: 175 RKVIITIQYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELW 234

Query: 239 RRLRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQY 298
                  VE+LQDV ++  R++   + KP+ V+ +L S      ++G+L +L        
Sbjct: 235 ETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTSWC----ITGVLDMLNN------ 284

Query: 299 YWVDVMLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFGVFGCQYFSSGKYYWE 358
           + VD  L+       +++S D R+V           +P    +F V+  Q F+SGK+YWE
Sbjct: 285 FRVDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPMDPQGVESFAVWCAQAFTSGKHYWE 344

Query: 359 VDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEY 418
           VDV+    WILGV       ++   +    D    +  + S+    Y             
Sbjct: 345 VDVTHSSNWILGVCRD----SRTADTNIVIDSDKTFFSISSKTSNHY------------- 387

Query: 419 NAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPA 478
                S S++   L  ++  P   +GVFLDY+ G VSFF+V+  G+LIY F    FS P 
Sbjct: 388 -----SLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSK-GSLIYGFPPSSFSSPL 441

Query: 479 YPYF 482
            P+F
Sbjct: 442 RPFF 445


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,085,779
Number of Sequences: 37866
Number of extensions: 823142
Number of successful extensions: 4659
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 260
Number of HSP's successfully gapped in prelim test: 348
Number of HSP's that attempted gapping in prelim test: 3487
Number of HSP's gapped (non-prelim): 1037
length of query: 498
length of database: 18,247,518
effective HSP length: 106
effective length of query: 392
effective length of database: 14,233,722
effective search space: 5579619024
effective search space used: 5579619024
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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