Guide to the Human Genome
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Search of human proteins with 239749060

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239749060 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
         (336 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239754500 PREDICTED: Leucine-rich repeat-containing protein E...   691   0.0  
gi|239749060 PREDICTED: Leucine-rich repeat-containing protein E...   691   0.0  
gi|239743086 PREDICTED: Leucine-rich repeat-containing protein E...   691   0.0  
gi|239508737 PREDICTED: Leucine-rich repeat-containing protein E...   691   0.0  
gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo...    61   1e-09
gi|55743114 leucine rich repeat containing 49 [Homo sapiens]           55   1e-07
gi|14042939 chromosome 10 open reading frame 11 [Homo sapiens]         54   2e-07
gi|239752518 PREDICTED: similar to leucine rich repeat containin...    54   2e-07
gi|53828918 Rab geranylgeranyltransferase alpha [Homo sapiens]         54   2e-07
gi|33469951 Rab geranylgeranyltransferase alpha [Homo sapiens]         54   2e-07
gi|239735605 leucine rich repeat containing 36 isoform 1 [Homo s...    54   3e-07
gi|194272228 leucine rich repeat containing 48 isoform b [Homo s...    52   6e-07
gi|194272226 leucine rich repeat containing 48 isoform b [Homo s...    52   6e-07
gi|194272224 leucine rich repeat containing 48 isoform a [Homo s...    52   6e-07
gi|194272222 leucine rich repeat containing 48 isoform a [Homo s...    52   6e-07
gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sap...    52   6e-07
gi|87298937 centrosomal protein 110kDa [Homo sapiens]                  48   1e-05
gi|62899065 centrosomal protein 72 kDa [Homo sapiens]                  47   2e-05
gi|21389483 leucine-rich repeats and guanylate kinase domain con...    47   2e-05
gi|157674358 leucine rich repeat containing 50 [Homo sapiens]          46   4e-05
gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]                   45   7e-05
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]                   45   7e-05
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]                   45   7e-05
gi|41281398 soc-2 suppressor of clear homolog [Homo sapiens]           45   7e-05
gi|61966709 leucine rich repeat containing 67 [Homo sapiens]           45   9e-05
gi|31621309 leucine rich repeat containing 6 [Homo sapiens]            45   9e-05
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof...    42   6e-04
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof...    42   6e-04
gi|148664213 leucine rich repeat containing 43 isoform 1 [Homo s...    41   0.001
gi|41350214 asporin [Homo sapiens]                                     41   0.002

>gi|239754500 PREDICTED: Leucine-rich repeat-containing protein
           ENSP00000371558 [Homo sapiens]
          Length = 336

 Score =  691 bits (1782), Expect = 0.0
 Identities = 336/336 (100%), Positives = 336/336 (100%)

Query: 1   MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60
           MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT
Sbjct: 1   MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60

Query: 61  LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120
           LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY
Sbjct: 61  LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120

Query: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180
           LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK
Sbjct: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180

Query: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240
           ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA
Sbjct: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240

Query: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300
           HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS
Sbjct: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300

Query: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336
           VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR
Sbjct: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336


>gi|239749060 PREDICTED: Leucine-rich repeat-containing protein
           ENSP00000371558 [Homo sapiens]
          Length = 336

 Score =  691 bits (1782), Expect = 0.0
 Identities = 336/336 (100%), Positives = 336/336 (100%)

Query: 1   MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60
           MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT
Sbjct: 1   MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60

Query: 61  LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120
           LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY
Sbjct: 61  LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120

Query: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180
           LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK
Sbjct: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180

Query: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240
           ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA
Sbjct: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240

Query: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300
           HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS
Sbjct: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300

Query: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336
           VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR
Sbjct: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336


>gi|239743086 PREDICTED: Leucine-rich repeat-containing protein
           ENSP00000371558 [Homo sapiens]
          Length = 336

 Score =  691 bits (1782), Expect = 0.0
 Identities = 336/336 (100%), Positives = 336/336 (100%)

Query: 1   MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60
           MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT
Sbjct: 1   MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60

Query: 61  LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120
           LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY
Sbjct: 61  LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120

Query: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180
           LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK
Sbjct: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180

Query: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240
           ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA
Sbjct: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240

Query: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300
           HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS
Sbjct: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300

Query: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336
           VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR
Sbjct: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336


>gi|239508737 PREDICTED: Leucine-rich repeat-containing protein
           ENSP00000371558 [Homo sapiens]
          Length = 336

 Score =  691 bits (1782), Expect = 0.0
 Identities = 336/336 (100%), Positives = 336/336 (100%)

Query: 1   MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60
           MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT
Sbjct: 1   MSVCESWNCDGYVVMRKEQRAVHQAKSLFGATGGRGRINHRCFGRPCVLMSWDPNPVPRT 60

Query: 61  LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120
           LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY
Sbjct: 61  LRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKY 120

Query: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180
           LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK
Sbjct: 121 LWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVK 180

Query: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240
           ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA
Sbjct: 181 ELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFNHKKA 240

Query: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300
           HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS
Sbjct: 241 HIVQSIAFGGKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRS 300

Query: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336
           VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR
Sbjct: 301 VMTLTSMNWDTVPTREERYLEEEGTETAQMLTVTLR 336


>gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo
           sapiens]
          Length = 255

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 49/139 (35%), Positives = 71/139 (51%), Gaps = 7/139 (5%)

Query: 112 LSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEI-EGLHY-LPSLHILLLHH 169
           L +F  + +      KL G   L R   L  L +NNN I  I EGL   LP L  L+L +
Sbjct: 41  LDQFDAIDFSDNEIRKLDGFPLLRR---LKTLLVNNNRICRIGEGLDQALPCLTELILTN 97

Query: 170 NELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERR 229
           N L  +   +  L  + +L  LS+ +NP+     YRLY+IY +P V +LD  +V  KER+
Sbjct: 98  NSLVEL-GDLDPLASLKSLTYLSILRNPVTNKKHYRLYVIYKVPQVRVLDFQKVKLKERQ 156

Query: 230 SMITIFNHKK-AHIVQSIA 247
               +F  K+ A + + IA
Sbjct: 157 EAEKMFKGKRGAQLAKDIA 175


>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
          Length = 686

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 57/241 (23%), Positives = 107/241 (44%), Gaps = 31/241 (12%)

Query: 60  TLRCWRLRRASETALQSSRRAVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLK 119
           TLRC R+    +  ++        ++    + +  DV +L     ++T++ +++   +L+
Sbjct: 154 TLRCLRVLLLGKNRIK--------KISNLENLKSLDVLDLH--GNQITKIENINHLCELR 203

Query: 120 YLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATV 179
            L L  N L  +  L     LTEL L +N I  +  +  LP L  L L  N +++ D+ V
Sbjct: 204 VLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFNNISSFDS-V 262

Query: 180 KELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIF---- 235
             L    +L  ++   NP+ Q + Y+  ++ ++  +  LD  ++TE+ERR    +     
Sbjct: 263 SCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLDMKRITEEERRMASVLAKKEE 322

Query: 236 -----NHKKAHIVQSIAFG-GKVDASWDPKSPFKQKPAQRVPSDFAFANNVDKTVLDDPE 289
                +HK++ + +        V   WD +        QRV +    A N D+   D P+
Sbjct: 323 EKKRESHKQSLLKEKKRLTINNVARQWDLQQ-------QRVAN---IATNEDRKDSDSPQ 372

Query: 290 D 290
           D
Sbjct: 373 D 373



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 6/132 (4%)

Query: 67  RRASETALQSSRRAVEDQ-LKICGHRRDADVFELF-LSKKELTEVIDLSRFKKLKYLWLH 124
           R + E  L S R ++E Q L +C      D   L       +T + ++S  +KL  L L+
Sbjct: 83  RSSEEKILYSDRLSLERQKLTVCPIINGEDHLRLLNFQHNFITRIQNISNLQKLISLDLY 142

Query: 125 HNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVKELKG 184
            N++  I+ L+   CL  L L  N I +I  L  L SL +L LH N++T I+     +  
Sbjct: 143 DNQIEEISGLSTLRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIE----NINH 198

Query: 185 MLNLKILSLYQN 196
           +  L++L+L +N
Sbjct: 199 LCELRVLNLARN 210


>gi|14042939 chromosome 10 open reading frame 11 [Homo sapiens]
          Length = 198

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 40/130 (30%), Positives = 62/130 (47%), Gaps = 16/130 (12%)

Query: 119 KYLWL---HHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNI 175
           KYL L   H +    +  L+    L EL L+NN + +   L  LP LH L L+ N +T++
Sbjct: 3   KYLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDL 62

Query: 176 DATVKELKGMLN-LKILSLYQNPLC------------QYNLYRLYIIYHLPGVELLDRNQ 222
           +  +  L  +   L+ LSL  N  C             Y  YR +++Y LP ++ LD  +
Sbjct: 63  ENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQK 122

Query: 223 VTEKERRSMI 232
           VT +ER   +
Sbjct: 123 VTRQEREEAL 132


>gi|239752518 PREDICTED: similar to leucine rich repeat containing
           50, partial [Homo sapiens]
          Length = 489

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 22/202 (10%)

Query: 99  LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHY 158
           L L   ++T++ +++   +L+ L L  N L  +  L     LTEL L +N I  +  +  
Sbjct: 8   LDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDN 67

Query: 159 LPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELL 218
           LP L  L L  N +++ D+ V  L    +L  ++   NP+ Q + Y+  ++ ++  +  L
Sbjct: 68  LPCLQHLFLSFNNISSFDS-VSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQL 126

Query: 219 DRNQVTEKERRSMITIF---------NHKKAHIVQSIAFG-GKVDASWDPKSPFKQKPAQ 268
           D  ++TE+ERR    +          +HK++ + +        V   WD +        Q
Sbjct: 127 DMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQ--------Q 178

Query: 269 RVPSDFAFANNVDKTVLDDPED 290
           RV +    A N D+   D P+D
Sbjct: 179 RVAN---IATNEDRKDSDSPQD 197


>gi|53828918 Rab geranylgeranyltransferase alpha [Homo sapiens]
          Length = 567

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 39/108 (36%), Positives = 58/108 (53%), Gaps = 2/108 (1%)

Query: 94  ADVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGIT-FLTRNYCLTELYLNNNAIFE 152
           A+V  L L+ K+LT +  L +   + +L L HN+L  +   L    CL  L  ++NAI  
Sbjct: 441 AEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIES 500

Query: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQ 200
           ++G+  LP L  LLL +N L    A ++ L     L +L+L  NPLCQ
Sbjct: 501 LDGVTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRLVLLNLQGNPLCQ 547


>gi|33469951 Rab geranylgeranyltransferase alpha [Homo sapiens]
          Length = 567

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 39/108 (36%), Positives = 58/108 (53%), Gaps = 2/108 (1%)

Query: 94  ADVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGIT-FLTRNYCLTELYLNNNAIFE 152
           A+V  L L+ K+LT +  L +   + +L L HN+L  +   L    CL  L  ++NAI  
Sbjct: 441 AEVRVLHLAHKDLTVLCHLEQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQASDNAIES 500

Query: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQ 200
           ++G+  LP L  LLL +N L    A ++ L     L +L+L  NPLCQ
Sbjct: 501 LDGVTNLPRLQELLLCNNRLQQ-PAVLQPLASCPRLVLLNLQGNPLCQ 547


>gi|239735605 leucine rich repeat containing 36 isoform 1 [Homo
           sapiens]
          Length = 754

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 44/134 (32%), Positives = 68/134 (50%), Gaps = 11/134 (8%)

Query: 99  LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYC-LTELYLNNNAIFEIEGLH 157
           L L + EL E + L           +  K+H I    RN+  L  L L+ N I  ++G+ 
Sbjct: 18  LTLEQPELVESLSLQGS--------YAGKIHSIGDAFRNFKNLRSLDLSRNLITSLKGIQ 69

Query: 158 YLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNL-YRLYIIYHLPGVE 216
           YL SL  L L++N + ++   V  L+ +  LK L L  NP+ + +  YRL+ +Y L  +E
Sbjct: 70  YLCSLQDLNLYYNNIPSL-VEVSRLQPLPFLKELDLRLNPVVRKDTDYRLFAVYTLQTLE 128

Query: 217 LLDRNQVTEKERRS 230
            LD   V E ER++
Sbjct: 129 KLDDRTVREGERKA 142


>gi|194272228 leucine rich repeat containing 48 isoform b [Homo
           sapiens]
          Length = 457

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 21/156 (13%)

Query: 95  DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIE 154
           DV  L L  + +  + +L +F+ L+ L L +N +  I  L     L  L L+ N I  IE
Sbjct: 44  DVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIE 103

Query: 155 GLHYLPSLHILLLHHNELTNI---DATVK---------ELKGMLN---------LKILSL 193
           GL  L +L  L L +N ++ I   DA VK          +  M+N         L+ LSL
Sbjct: 104 GLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSL 163

Query: 194 YQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERR 229
            +NP+ +   Y+++I  +LP +  LD  ++ +  ++
Sbjct: 164 SRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKK 199


>gi|194272226 leucine rich repeat containing 48 isoform b [Homo
           sapiens]
          Length = 457

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 21/156 (13%)

Query: 95  DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIE 154
           DV  L L  + +  + +L +F+ L+ L L +N +  I  L     L  L L+ N I  IE
Sbjct: 44  DVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIE 103

Query: 155 GLHYLPSLHILLLHHNELTNI---DATVK---------ELKGMLN---------LKILSL 193
           GL  L +L  L L +N ++ I   DA VK          +  M+N         L+ LSL
Sbjct: 104 GLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSL 163

Query: 194 YQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERR 229
            +NP+ +   Y+++I  +LP +  LD  ++ +  ++
Sbjct: 164 SRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKK 199


>gi|194272224 leucine rich repeat containing 48 isoform a [Homo
           sapiens]
          Length = 523

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 21/156 (13%)

Query: 95  DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIE 154
           DV  L L  + +  + +L +F+ L+ L L +N +  I  L     L  L L+ N I  IE
Sbjct: 44  DVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIE 103

Query: 155 GLHYLPSLHILLLHHNELTNI---DATVK---------ELKGMLN---------LKILSL 193
           GL  L +L  L L +N ++ I   DA VK          +  M+N         L+ LSL
Sbjct: 104 GLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSL 163

Query: 194 YQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERR 229
            +NP+ +   Y+++I  +LP +  LD  ++ +  ++
Sbjct: 164 SRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKK 199


>gi|194272222 leucine rich repeat containing 48 isoform a [Homo
           sapiens]
          Length = 523

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 45/156 (28%), Positives = 75/156 (48%), Gaps = 21/156 (13%)

Query: 95  DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIE 154
           DV  L L  + +  + +L +F+ L+ L L +N +  I  L     L  L L+ N I  IE
Sbjct: 44  DVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIE 103

Query: 155 GLHYLPSLHILLLHHNELTNI---DATVK---------ELKGMLN---------LKILSL 193
           GL  L +L  L L +N ++ I   DA VK          +  M+N         L+ LSL
Sbjct: 104 GLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSL 163

Query: 194 YQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERR 229
            +NP+ +   Y+++I  +LP +  LD  ++ +  ++
Sbjct: 164 SRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKK 199


>gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo
           sapiens]
          Length = 360

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 42/142 (29%), Positives = 65/142 (45%), Gaps = 21/142 (14%)

Query: 99  LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHY 158
           LFL K ++T++ +L     L  L +  N+L  I  L     L ELYL++N I  IEGL  
Sbjct: 213 LFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLEN 272

Query: 159 LPSLHILLLHHNELTNID---------------------ATVKELKGMLNLKILSLYQNP 197
              L +L +  N +  I+                     + + ELKG  +L+ + L +NP
Sbjct: 273 NNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNP 332

Query: 198 LCQYNLYRLYIIYHLPGVELLD 219
           L +   YR  ++  LP V  +D
Sbjct: 333 LQKDPQYRRKVMLALPSVRQID 354



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 37/128 (28%), Positives = 65/128 (50%), Gaps = 13/128 (10%)

Query: 99  LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHY 158
           L +S   L  +  + +  +LK L+L +NK+  I  L+  + L  L L +N I  IE +  
Sbjct: 147 LDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDT 206

Query: 159 LPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQ-------YNLYRLYIIYH 211
           L +L  L L  N++T +    + L  + NL +LS+  N L +        NL  LY+ ++
Sbjct: 207 LTNLESLFLGKNKITKL----QNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHN 262

Query: 212 LPGVELLD 219
             G+E+++
Sbjct: 263 --GIEVIE 268



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 37/121 (30%), Positives = 56/121 (46%), Gaps = 8/121 (6%)

Query: 93  DADVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFE 152
           D D  ++ L+   + ++      KK+K L L  N +  I  L     L EL L +N I +
Sbjct: 75  DRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKK 134

Query: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQY----NLYRLYI 208
           IE L  L  L IL +  N L NI+   K    +  LK L L  N + +     NL++L +
Sbjct: 135 IENLEALTELEILDISFNLLRNIEGVDK----LTRLKKLFLVNNKISKIENLSNLHQLQM 190

Query: 209 I 209
           +
Sbjct: 191 L 191


>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
          Length = 2325

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 49/164 (29%), Positives = 77/164 (46%), Gaps = 26/164 (15%)

Query: 99  LFLSK---KELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEG 155
           L LSK   K+   + +L +  KL+ L L +N +  I  L +   L EL L+ N I +IEG
Sbjct: 105 LSLSKDGGKKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEG 164

Query: 156 LHYLPSLHILLLHHNELTNIDATV-KELKGM--LNLK--------------------ILS 192
           +  + +L  L L  NE+ +I   + K+LK +  LNLK                     L 
Sbjct: 165 IENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLI 224

Query: 193 LYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFN 236
           L +NP+     Y  + I+HL  +E L+   VT ++R+     F+
Sbjct: 225 LVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFS 268


>gi|62899065 centrosomal protein 72 kDa [Homo sapiens]
          Length = 647

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 35/125 (28%), Positives = 64/125 (51%), Gaps = 9/125 (7%)

Query: 111 DLSRFKKLKYLWLHHNKL----HGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILL 166
           DL+  + L     +  K+    H +  LT    L  L L+ N++  +EG+ YL +L  L 
Sbjct: 26  DLAELQSLSIPGTYQEKITHLGHSLMSLTG---LKSLDLSRNSLVSLEGIQYLTALESLN 82

Query: 167 LHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNL-YRLYIIYHLPGVELLDRNQVTE 225
           L++N ++++ A V  L  +  L  +    NP+ +    YRL++++ LP ++ LD   V  
Sbjct: 83  LYYNCISSL-AEVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHLLPKLQQLDDRPVRA 141

Query: 226 KERRS 230
            ER++
Sbjct: 142 SERKA 146


>gi|21389483 leucine-rich repeats and guanylate kinase domain
           containing [Homo sapiens]
          Length = 825

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 44/178 (24%), Positives = 80/178 (44%), Gaps = 44/178 (24%)

Query: 102 SKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPS 161
           S  +++E+ DLS +  L  L L  N++  I+ L     L  L L NN I  I GL+ LP 
Sbjct: 201 SHNQISEICDLSAYHALTKLILDGNEIEEISGLEMCNNLIHLSLANNKITTINGLNKLP- 259

Query: 162 LHILLLHHNE------------LTNIDAT---VKELKGMLN------------------- 187
           + IL L +N+            L N+D +   +  L+G+ N                   
Sbjct: 260 IKILCLSNNQIEMITGLEDLKALQNLDLSHNQISSLQGLENHDLLEVINLEDNKIAELRE 319

Query: 188 ---------LKILSLYQNPLCQYNLYRLYIIYHLPGVELLDRNQVTEKERRSMITIFN 236
                    L++L+L +NP+ + + Y  ++I+ L  +  LD+ ++  +E+ S +  ++
Sbjct: 320 IEYIKNLPILRVLNLLENPIQEKSEYWFFVIFMLLRLTELDQKKIKVEEKVSAVNKYD 377


>gi|157674358 leucine rich repeat containing 50 [Homo sapiens]
          Length = 725

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 3/121 (2%)

Query: 99  LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHY 158
           L+L    + ++ +L    +L+ L+L  N L  I  L     L  L L+NN I  IE L  
Sbjct: 134 LWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLSNNYIKTIENLSC 193

Query: 159 LPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELL 218
           LP L+ L + HN L  ++  ++ L+  L L +L L  N L    +  L I+  +P + +L
Sbjct: 194 LPVLNTLQMAHNHLETVE-DIQHLQECLRLCVLDLSHNKLSDPEI--LSILESMPDLRVL 250

Query: 219 D 219
           +
Sbjct: 251 N 251


>gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
          Length = 421

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 39/114 (34%), Positives = 56/114 (49%), Gaps = 9/114 (7%)

Query: 92  RDADVFELFLSKKELTEV-IDLSRFKKL---KYLWLHHNKLHGITF-LTRNYCLTELYLN 146
           R   + EL+L   +LT+  +D + F KL   +YL L HN+L  +   L R   +  L+L 
Sbjct: 147 RQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAI--LHLG 204

Query: 147 NNAIFEIEG--LHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPL 198
            N I ++E   LH    L  LLL HN+L +       L+ +  L  L LY N L
Sbjct: 205 RNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGL 258


>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
          Length = 510

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 39/114 (34%), Positives = 56/114 (49%), Gaps = 9/114 (7%)

Query: 92  RDADVFELFLSKKELTEV-IDLSRFKKL---KYLWLHHNKLHGITF-LTRNYCLTELYLN 146
           R   + EL+L   +LT+  +D + F KL   +YL L HN+L  +   L R   +  L+L 
Sbjct: 236 RQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAI--LHLG 293

Query: 147 NNAIFEIEG--LHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPL 198
            N I ++E   LH    L  LLL HN+L +       L+ +  L  L LY N L
Sbjct: 294 RNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGL 347



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 117 KLKYLWLHHNKLH-GITFLTRNYCLTELYLNNNAIFEIEGLHY--LPSLHILLLHHNELT 173
           +L++L + HNKL     FL R+  + +L  N   + EI  L +   P+L  + LH+N+L+
Sbjct: 123 QLQHLCVAHNKLSVAPQFLPRSLRVADLAANQ--VMEIFPLTFGEKPALRSVYLHNNQLS 180

Query: 174 NIDATVKELKGMLNLKILSLYQNPL 198
           N        +G   +  LSL  N L
Sbjct: 181 NAGLPPDAFRGSEAIATLSLSNNQL 205


>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
          Length = 512

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 39/114 (34%), Positives = 56/114 (49%), Gaps = 9/114 (7%)

Query: 92  RDADVFELFLSKKELTEV-IDLSRFKKL---KYLWLHHNKLHGITF-LTRNYCLTELYLN 146
           R   + EL+L   +LT+  +D + F KL   +YL L HN+L  +   L R   +  L+L 
Sbjct: 238 RQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAI--LHLG 295

Query: 147 NNAIFEIEG--LHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPL 198
            N I ++E   LH    L  LLL HN+L +       L+ +  L  L LY N L
Sbjct: 296 RNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGL 349



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 117 KLKYLWLHHNKLH-GITFLTRNYCLTELYLNNNAIFEIEGLHY--LPSLHILLLHHNELT 173
           +L++L + HNKL     FL R+  + +L  N   + EI  L +   P+L  + LH+N+L+
Sbjct: 125 QLQHLCVAHNKLSVAPQFLPRSLRVADLAANQ--VMEIFPLTFGEKPALRSVYLHNNQLS 182

Query: 174 NIDATVKELKGMLNLKILSLYQNPL 198
           N        +G   +  LSL  N L
Sbjct: 183 NAGLPPDAFRGSEAIATLSLSNNQL 207


>gi|41281398 soc-2 suppressor of clear homolog [Homo sapiens]
          Length = 582

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 34/99 (34%), Positives = 52/99 (52%), Gaps = 3/99 (3%)

Query: 95  DVFELFLSKKELTEVID-LSRFKKLKYLWLHHNKLHGI-TFLTRNYCLTELYLNNNAIFE 152
           ++  L LS+  LT + D L   KKL+ L L HNKL  I + + R   LT LYL  N I  
Sbjct: 147 NLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITT 206

Query: 153 IE-GLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKI 190
           +E  +  L  L +L +  N++  + A + EL  ++ L +
Sbjct: 207 VEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDV 245


>gi|61966709 leucine rich repeat containing 67 [Homo sapiens]
          Length = 228

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 34/90 (37%), Positives = 45/90 (50%), Gaps = 4/90 (4%)

Query: 102 SKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPS 161
           S K +  + DLS  K L  L+L+ N +  IT L     LT LYL NN I  IE L  L  
Sbjct: 36  SDKNIDAIEDLSLCKNLSVLYLYDNCISQITNLNYATNLTHLYLQNNCISCIENLRSLKK 95

Query: 162 LHILLLHHNELTNIDATVKELKGMLNLKIL 191
           L  L L  N +    A ++ L+G+  L+ L
Sbjct: 96  LEKLYLGGNYI----AVIEGLEGLGELREL 121



 Score = 33.1 bits (74), Expect = 0.36
 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 6/93 (6%)

Query: 80  AVEDQLKICGHRRDADVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYC 139
           A+ED L +C      ++  L+L    ++++ +L+    L +L+L +N +  I  L     
Sbjct: 42  AIED-LSLC-----KNLSVLYLYDNCISQITNLNYATNLTHLYLQNNCISCIENLRSLKK 95

Query: 140 LTELYLNNNAIFEIEGLHYLPSLHILLLHHNEL 172
           L +LYL  N I  IEGL  L  L  L + +  L
Sbjct: 96  LEKLYLGGNYIAVIEGLEGLGELRELHVENQRL 128



 Score = 32.0 bits (71), Expect = 0.80
 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 12/77 (15%)

Query: 134 LTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSL 193
           L ++ C+  L ++NN I +I  L  L +L+ L+   N+L +    VK+L+ +LN K++ L
Sbjct: 144 LAKSLCI--LNISNNNIDDITDLELLENLNQLIAVDNQLLH----VKDLEFLLN-KLMKL 196

Query: 194 YQ-----NPLCQYNLYR 205
           ++     NP+C    YR
Sbjct: 197 WKIDLNGNPVCLKPKYR 213



 Score = 28.5 bits (62), Expect = 8.9
 Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 1/73 (1%)

Query: 116 KKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILLLHHNELTNI 175
           KK+ ++      +  I  L+    L+ LYL +N I +I  L+Y  +L  L L +N ++ I
Sbjct: 28  KKITHINFSDKNIDAIEDLSLCKNLSVLYLYDNCISQITNLNYATNLTHLYLQNNCISCI 87

Query: 176 DATVKELKGMLNL 188
           +  ++ LK +  L
Sbjct: 88  E-NLRSLKKLEKL 99


>gi|31621309 leucine rich repeat containing 6 [Homo sapiens]
          Length = 466

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 37/135 (27%), Positives = 63/135 (46%), Gaps = 25/135 (18%)

Query: 95  DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNN-NAIFEI 153
           D+  L+L    + ++ ++S+ KKL+YL                     L LNN   I  +
Sbjct: 45  DLKILYLQNNLIGKIENVSKLKKLEYL--------------------NLALNNIEKIENL 84

Query: 154 EGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLP 213
           EG   L  L + +    EL++I    K L+  ++LK L L  NP   ++ YR +++  LP
Sbjct: 85  EGCEELAKLDLTVNFIGELSSI----KNLQHNIHLKELFLMGNPCASFDHYREFVVATLP 140

Query: 214 GVELLDRNQVTEKER 228
            ++ LD  ++   ER
Sbjct: 141 QLKWLDGKEIEPSER 155


>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform 1
            [Homo sapiens]
          Length = 1722

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 2/125 (1%)

Query: 99   LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYC--LTELYLNNNAIFEIEGL 156
            L L    L+E+  L     L+ L L  N +  +   +  +   L  + ++ N++ +I  L
Sbjct: 1018 LKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQNITISQNSLTKIVPL 1077

Query: 157  HYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVE 216
             +  SL  L + HN L+++ + +K      +L  LSL  NPL Q   +R  ++  LP + 
Sbjct: 1078 FHFVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSLLKVLPALR 1137

Query: 217  LLDRN 221
            +L+ N
Sbjct: 1138 ILNGN 1142



 Score = 35.4 bits (80), Expect = 0.073
 Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 3/78 (3%)

Query: 99  LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLT-RNYCLTELYLNNNAIFEIEGLH 157
           L L +  LT +  LS  KKLKY+    N +  I      N C+  + LN N +  + GL 
Sbjct: 823 LSLRRCGLTSLHSLSNCKKLKYIDAQENHIEAIECENLENLCV--VLLNKNQLTSLHGLD 880

Query: 158 YLPSLHILLLHHNELTNI 175
              ++  L L +N++T I
Sbjct: 881 GCTNIQCLELSYNKITRI 898


>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform 2
            [Homo sapiens]
          Length = 1336

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 2/125 (1%)

Query: 99   LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYC--LTELYLNNNAIFEIEGL 156
            L L    L+E+  L     L+ L L  N +  +   +  +   L  + ++ N++ +I  L
Sbjct: 1018 LKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQNITISQNSLTKIVPL 1077

Query: 157  HYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVE 216
             +  SL  L + HN L+++ + +K      +L  LSL  NPL Q   +R  ++  LP + 
Sbjct: 1078 FHFVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSLLKVLPALR 1137

Query: 217  LLDRN 221
            +L+ N
Sbjct: 1138 ILNGN 1142



 Score = 35.4 bits (80), Expect = 0.073
 Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 3/78 (3%)

Query: 99  LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLT-RNYCLTELYLNNNAIFEIEGLH 157
           L L +  LT +  LS  KKLKY+    N +  I      N C+  + LN N +  + GL 
Sbjct: 823 LSLRRCGLTSLHSLSNCKKLKYIDAQENHIEAIECENLENLCV--VLLNKNQLTSLHGLD 880

Query: 158 YLPSLHILLLHHNELTNI 175
              ++  L L +N++T I
Sbjct: 881 GCTNIQCLELSYNKITRI 898


>gi|148664213 leucine rich repeat containing 43 isoform 1 [Homo
           sapiens]
          Length = 656

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 7/138 (5%)

Query: 98  ELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRN--YCLTELYLNNNAIF-EIE 154
           EL LS   + EV   +    LK L L+ N++  +  L  +    L  L L +N +   +E
Sbjct: 153 ELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLLGPLE 212

Query: 155 GLH----YLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIY 210
            L+    + P+L  L L  N+LT++ + V  L+ + +L++L L  NPL     YR   I 
Sbjct: 213 SLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVPYYRGLTID 272

Query: 211 HLPGVELLDRNQVTEKER 228
            L  + +LD   V+  E+
Sbjct: 273 SLAQLCVLDDITVSPNEK 290



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 50/202 (24%), Positives = 83/202 (41%), Gaps = 17/202 (8%)

Query: 46  PCVLMSWDPNP-VPRTLRCWR-LRRASETALQSSRRAVEDQLKICGHRRDA--------- 94
           PC   SW+ +  +P+T R WR L    E  +      VE  L +   R            
Sbjct: 44  PCGAGSWNKSRFLPQTWRTWRELVPREEDVVSPGEETVEALLGLVRSRHSPWALLNNSNA 103

Query: 95  -DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITF-LTRNYCLTELYLNNNAIFE 152
            D F   L+ +    + D   +   + L +   K+  +   L +   L EL L+ N I E
Sbjct: 104 EDSFLRELAIRNPLTITDTFFYSYFRSLRVIDKKVTLVDKDLLKFLKLEELVLSANRIKE 163

Query: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYI-IYH 211
           ++  +  P+L +L L+ NE+++++           L+ L L  N L    L  LY+   H
Sbjct: 164 VDATNLPPTLKVLELYGNEISSMECLCAHPPA--GLQHLGLGHNKLLG-PLESLYVTANH 220

Query: 212 LPGVELLDRNQVTEKERRSMIT 233
            P +  LD       + +SM+T
Sbjct: 221 WPNLVSLDLGFNDLTDLQSMVT 242


>gi|41350214 asporin [Homo sapiens]
          Length = 380

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 33/105 (31%), Positives = 53/105 (50%), Gaps = 9/105 (8%)

Query: 102 SKKELTEVIDLSRFKKLKYLWLHHNKLHGIT--FLTRNYCLTELYLNNNAIFEI-EGLHY 158
           +K    E+ D  R+K+L+ L L +NK+  I    L     + E++L NN + +I  GL  
Sbjct: 251 NKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGLPE 310

Query: 159 LPSLHILLLHHNELTNIDA-----TVKELKGMLNLKILSLYQNPL 198
           L  L I+ LH N +  +       TV ++K  L    +SL+ NP+
Sbjct: 311 LKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSL-YSAISLFNNPV 354



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 5/83 (6%)

Query: 96  VFELFLSKKELTEVIDLSRF--KKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEI 153
           ++ L L+  +LT++   +    KKL+ L+L HN+L  I  L     L EL ++ N + +I
Sbjct: 128 LYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIP-LNLPKSLAELRIHENKVKKI 186

Query: 154 EGLHY--LPSLHILLLHHNELTN 174
           +   +  + +LH+L +  N L N
Sbjct: 187 QKDTFKGMNALHVLEMSANPLDN 209


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,667,809
Number of Sequences: 37866
Number of extensions: 542081
Number of successful extensions: 1429
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 76
Number of HSP's that attempted gapping in prelim test: 1266
Number of HSP's gapped (non-prelim): 183
length of query: 336
length of database: 18,247,518
effective HSP length: 103
effective length of query: 233
effective length of database: 14,347,320
effective search space: 3342925560
effective search space used: 3342925560
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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