Search of human proteins with 239748928

Search of human proteins with 239748928

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239748928 PREDICTED: hypothetical protein XP_002346859 [Homo
sapiens]
         (709 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239754438 PREDICTED: hypothetical protein [Homo sapiens]          1446   0.0  
gi|239748928 PREDICTED: hypothetical protein XP_002346859 [Homo ...  1446   0.0  
gi|239742950 PREDICTED: hypothetical protein XP_002342702 [Homo ...  1439   0.0  
gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]            49   1e-05
gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]            49   1e-05
gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]            48   3e-05
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]            48   3e-05
gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]          47   5e-05
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      43   9e-04
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             43   9e-04
gi|148886696 surfactant protein A2 [Homo sapiens]                      43   0.001
gi|146149162 surfactant, pulmonary-associated protein A2 [Homo s...    43   0.001
gi|122692281 hypothetical protein LOC645369 [Homo sapiens]             43   0.001
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       42   0.002
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       42   0.002
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    42   0.002
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     42   0.002
gi|27437008 kringle-containing transmembrane protein 2 isoform d...    42   0.002
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         42   0.003
gi|147903070 surfactant protein A1 [Homo sapiens]                      41   0.003
gi|38888175 surfactant, pulmonary-associated protein A1B [Homo s...    41   0.003
gi|15826862 coiled-coil domain containing 120 isoform 3 [Homo sa...    41   0.004
gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo s...    41   0.004
gi|254039612 coiled-coil domain containing 120 isoform 2 [Homo s...    41   0.004
gi|254039610 coiled-coil domain containing 120 isoform 1 [Homo s...    41   0.004
gi|169179422 PREDICTED: hypothetical protein [Homo sapiens]            41   0.004
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    40   0.006
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    40   0.006
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                40   0.006
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  40   0.007

>gi|239754438 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 709

 Score = 1446 bits (3744), Expect = 0.0
 Identities = 709/709 (100%), Positives = 709/709 (100%)

Query: 1   MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP 60
           MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP
Sbjct: 1   MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP 60

Query: 61  LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR 120
           LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR
Sbjct: 61  LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR 120

Query: 121 GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF 180
           GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF
Sbjct: 121 GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF 180

Query: 181 HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV 240
           HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV
Sbjct: 181 HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV 240

Query: 241 VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLRGWLRALRG 300
           VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLRGWLRALRG
Sbjct: 241 VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLRGWLRALRG 300

Query: 301 PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA 360
           PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA
Sbjct: 301 PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA 360

Query: 361 FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS 420
           FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS
Sbjct: 361 FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS 420

Query: 421 GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS 480
           GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS
Sbjct: 421 GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS 480

Query: 481 STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVVEGCA 540
           STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVVEGCA
Sbjct: 481 STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVVEGCA 540

Query: 541 WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK 600
           WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK
Sbjct: 541 WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK 600

Query: 601 RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ 660
           RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ
Sbjct: 601 RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ 660

Query: 661 RNRLRVTHPPESAPEEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR 709
           RNRLRVTHPPESAPEEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR
Sbjct: 661 RNRLRVTHPPESAPEEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR 709


>gi|239748928 PREDICTED: hypothetical protein XP_002346859 [Homo
           sapiens]
          Length = 709

 Score = 1446 bits (3744), Expect = 0.0
 Identities = 709/709 (100%), Positives = 709/709 (100%)

Query: 1   MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP 60
           MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP
Sbjct: 1   MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP 60

Query: 61  LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR 120
           LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR
Sbjct: 61  LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR 120

Query: 121 GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF 180
           GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF
Sbjct: 121 GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF 180

Query: 181 HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV 240
           HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV
Sbjct: 181 HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV 240

Query: 241 VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLRGWLRALRG 300
           VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLRGWLRALRG
Sbjct: 241 VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLRGWLRALRG 300

Query: 301 PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA 360
           PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA
Sbjct: 301 PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA 360

Query: 361 FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS 420
           FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS
Sbjct: 361 FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS 420

Query: 421 GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS 480
           GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS
Sbjct: 421 GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS 480

Query: 481 STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVVEGCA 540
           STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVVEGCA
Sbjct: 481 STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVVEGCA 540

Query: 541 WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK 600
           WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK
Sbjct: 541 WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK 600

Query: 601 RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ 660
           RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ
Sbjct: 601 RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ 660

Query: 661 RNRLRVTHPPESAPEEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR 709
           RNRLRVTHPPESAPEEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR
Sbjct: 661 RNRLRVTHPPESAPEEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR 709


>gi|239742950 PREDICTED: hypothetical protein XP_002342702 [Homo
           sapiens]
          Length = 709

 Score = 1439 bits (3726), Expect = 0.0
 Identities = 706/709 (99%), Positives = 706/709 (99%)

Query: 1   MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP 60
           MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP
Sbjct: 1   MFGLGRAGHFSGHCRPAHAEMVPGLQAVGVRSSRRSGRSAQLSASTSLCPAVEVVGERAP 60

Query: 61  LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR 120
           LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR
Sbjct: 61  LVLGLDLRQQRAALDRELAGDGPRRLLPALGRSALGDWAGIGHPLGWGLLGGSPGAAGGR 120

Query: 121 GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF 180
           GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF
Sbjct: 121 GGHGLEGTAPALPLRGGRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRF 180

Query: 181 HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV 240
           HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV
Sbjct: 181 HFLFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHV 240

Query: 241 VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLRGWLRALRG 300
           VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPL GWLRALRG
Sbjct: 241 VPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLGGWLRALRG 300

Query: 301 PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA 360
           PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA
Sbjct: 301 PREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSA 360

Query: 361 FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS 420
           FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS
Sbjct: 361 FSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSAS 420

Query: 421 GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS 480
           GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS
Sbjct: 421 GGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTS 480

Query: 481 STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVVEGCA 540
           STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGV EGCA
Sbjct: 481 STCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVAEGCA 540

Query: 541 WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK 600
           WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK
Sbjct: 541 WDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAK 600

Query: 601 RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ 660
           RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ
Sbjct: 601 RLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQ 660

Query: 661 RNRLRVTHPPESAPEEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR 709
           RNRLRVTHPPESAP EVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR
Sbjct: 661 RNRLRVTHPPESAPGEVRMNQICSQGSKTLLVLEAPGGRFGTRQLLLLR 709


>gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 107/382 (28%), Positives = 133/382 (34%), Gaps = 84/382 (21%)

Query: 19  AEMVPGLQAVGVRSSRR----SGRSAQLSASTSLCPAVEVVGERAPLVLGLDLRQQRAAL 74
           A+  P   A G RSS R     GR     A T            AP+      R +R  L
Sbjct: 34  AQPPPHTPATGTRSSYRLLPQKGRGNLRGAPT------------APVSFS---RIRRNPL 78

Query: 75  DRELAGDGPRRLLPALG-RSALGDWAGIGHP-LGWGLLGGSPGAA----GGRGGHGLEGT 128
             +L+G  PRR    L   S  GD      P  G G     P       GGR G   EG 
Sbjct: 79  RTQLSGSPPRRPTSVLRLASPAGDLPRRPRPRAGGGRHSPRPAVGTIFRGGRKGRLREGR 138

Query: 129 APALPLRG-GRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRFHFLFRRG 187
                LRG G+ RGW   P R+ S L     AGLG  A  GG A   G            
Sbjct: 139 GA---LRGSGKRRGWGLRPQRVRSRL-----AGLG--APRGGAAAPRGW----------- 177

Query: 188 VIAGRVWRHLVVEHRVVPG-SALRELGVRAGGVGGFLRPPPP---------PRPTAA--- 234
              G+    L V    +P  +ALR  G  + G GG  RP PP         PRP      
Sbjct: 178 --GGQGAERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQPPSGRPRPRRTRLL 235

Query: 235 GPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLR-- 292
           G         A+ R G        +   S  + A   ++  A P+ GG+ G   A  R  
Sbjct: 236 GSAERHTGRAALARHGQLSRPHAAVRNSSRGRGAATSVSAAARPTRGGARGHRRADGRAR 295

Query: 293 --------------GWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRK 338
                         G L+  RG +   +AH   +    SP P A RS +     PL    
Sbjct: 296 GGCAQLRAGTPSAPGGLQDCRGRQGEENAHPFRSGAPFSPHPHASRSTLAAQLLPLPQP- 354

Query: 339 ASCSWPAPGEASSPGLRAGVSA 360
                P P + + P L   +SA
Sbjct: 355 -----PPPPKLAPPPLPPWLSA 371


>gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 107/382 (28%), Positives = 133/382 (34%), Gaps = 84/382 (21%)

Query: 19  AEMVPGLQAVGVRSSRR----SGRSAQLSASTSLCPAVEVVGERAPLVLGLDLRQQRAAL 74
           A+  P   A G RSS R     GR     A T            AP+      R +R  L
Sbjct: 34  AQPPPHTPATGTRSSYRLLPQKGRGNLRGAPT------------APVSFS---RIRRNPL 78

Query: 75  DRELAGDGPRRLLPALG-RSALGDWAGIGHP-LGWGLLGGSPGAA----GGRGGHGLEGT 128
             +L+G  PRR    L   S  GD      P  G G     P       GGR G   EG 
Sbjct: 79  RTQLSGSPPRRPTSVLRLASPAGDLPRRPRPRAGGGRHSPRPAVGTIFRGGRKGRLREGR 138

Query: 129 APALPLRG-GRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRFHFLFRRG 187
                LRG G+ RGW   P R+ S L     AGLG  A  GG A   G            
Sbjct: 139 GA---LRGSGKRRGWGLRPQRVRSRL-----AGLG--APRGGAAAPRGW----------- 177

Query: 188 VIAGRVWRHLVVEHRVVPG-SALRELGVRAGGVGGFLRPPPP---------PRPTAA--- 234
              G+    L V    +P  +ALR  G  + G GG  RP PP         PRP      
Sbjct: 178 --GGQGAERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQPPSGRPRPRRTRLL 235

Query: 235 GPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLR-- 292
           G         A+ R G        +   S  + A   ++  A P+ GG+ G   A  R  
Sbjct: 236 GSAERHTGRAALARHGQLSRPHAAVRNSSRGRGAATSVSAAARPTRGGARGHRRADGRAR 295

Query: 293 --------------GWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRK 338
                         G L+  RG +   +AH   +    SP P A RS +     PL    
Sbjct: 296 GGCAQLRAGTPSAPGGLQDCRGRQGEENAHPFRSGAPFSPHPHASRSTLAAQLLPLPQP- 354

Query: 339 ASCSWPAPGEASSPGLRAGVSA 360
                P P + + P L   +SA
Sbjct: 355 -----PPPPKLAPPPLPPWLSA 371


>gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 106/382 (27%), Positives = 133/382 (34%), Gaps = 84/382 (21%)

Query: 19  AEMVPGLQAVGVRSSRR----SGRSAQLSASTSLCPAVEVVGERAPLVLGLDLRQQRAAL 74
           A+  P   A G RSS R     GR     A T            AP+      R +R  L
Sbjct: 34  AQPPPHTPATGTRSSYRLLPQKGRGNLRGAPT------------APVSFS---RIRRNPL 78

Query: 75  DRELAGDGPRRLLPALG-RSALGDWAGIGHP-LGWGLLGGSPGAA----GGRGGHGLEGT 128
             +L+G  PRR    L   S  GD      P  G G     P       GGR G   EG 
Sbjct: 79  RTQLSGSPPRRPTSVLRLASPAGDLPRRPRPRAGGGRHSPRPAVGTIFRGGRKGRLREGR 138

Query: 129 APALPLRG-GRSRGWLFAPVRLPSELPFGTGAGLGLWARSGGNAPVEGCPRRFHFLFRRG 187
                +RG G+ RGW   P R+ S L     AGLG  A  GG A   G            
Sbjct: 139 GA---VRGSGKRRGWGLRPQRVRSRL-----AGLG--APRGGAAAPRGW----------- 177

Query: 188 VIAGRVWRHLVVEHRVVPG-SALRELGVRAGGVGGFLRPPPP---------PRPTAA--- 234
              G+    L V    +P  +ALR  G  + G GG  RP PP         PRP      
Sbjct: 178 --GGQGAERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQPPSGRPRPRRTRLL 235

Query: 235 GPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSPGKSDAPLR-- 292
           G         A+ R G        +   S  + A   ++  A P+ GG+ G   A  R  
Sbjct: 236 GSAERHTGRAALARHGQLSRPHAAVRNSSRGRGAATSVSAAARPTRGGARGHRRADGRAR 295

Query: 293 --------------GWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRK 338
                         G L+  RG +   +AH   +    SP P A RS +     PL    
Sbjct: 296 GGCAQLRAGTPSAPGGLQDCRGRQGEENAHPFRSGAPFSPHPHASRSTLAAQLLPLPQP- 354

Query: 339 ASCSWPAPGEASSPGLRAGVSA 360
                P P + + P L   +SA
Sbjct: 355 -----PPPPKLAPPPLPPWLSA 371


>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1230

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 107/417 (25%), Positives = 143/417 (34%), Gaps = 72/417 (17%)

Query: 273 AVCAAPSAGGSPGKSDA----PLRGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVG 328
           A C +PSA G+   SD+    P   W+         SS     +   +  S  +   WV 
Sbjct: 230 ASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVC 289

Query: 329 DPGAPLTPRKASCSWPAPGEASSPGL-RAGVSAFSCLEEFPGEECSCLAVVVASGKGSPS 387
              +  +   +  S P+   +SSP + RA   + S    F     S  +    SG  S S
Sbjct: 290 PSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPS---DSGWTSHS 346

Query: 388 ASRGSNWGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSG---------SSPSASRG 438
           AS  S   +S  W   +A+ A+     G +S S   A P  SG         +SPSAS  
Sbjct: 347 ASGVSTTSDS-GWASPSASGASTSSDSGWASPSASWASPSASGASTPSDSGWASPSASGA 405

Query: 439 FSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLG---GSK 495
                PS     CF         P L A +  TV     S  S C    L + G     +
Sbjct: 406 SMPSAPSLCPGSCF---------PQLTARTGFTVVGFPFSLLSHCISLCLPEFGIFVSVE 456

Query: 496 HLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVVEGCAWDSAYSAP----GPV 551
            L P LA   +  +R  +  R  P L S      PS  GV  G A D     P     P+
Sbjct: 457 SLAP-LAILTLVHSRPLAQPRPQPSLSSLDS---PSARGVRVGLARDHLCCLPISVFSPL 512

Query: 552 PRHT----------------CGSGVARLEPQGPAHLCEGAGPPAND-------PQRSQEG 588
           P                   CG G  R      AH    AG    +        Q + +G
Sbjct: 513 PLQNLLQVKGLFDGTSGCPHCGLGGHR------AHFLPHAGLAGTELLPLRLLAQLAPQG 566

Query: 589 GKPGLLISPGAKRLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFR 645
              G L+  G       A+   REG +     +  P    AL GL E     G P+R
Sbjct: 567 CAEGWLVLQGEGE-GPQAQGPLREGRE----VSQAPETVSALLGLQEQLPGEGLPWR 618



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 50/177 (28%), Positives = 70/177 (39%), Gaps = 23/177 (12%)

Query: 276 AAPSAGGSPGKSDAPLRGWLR-ALRGPREPS-------SAHTLGAPLGASPSPPAGRSWV 327
           A+PSA G+   SD+   GW   +  G   PS       SA     P  +  + P+  SW 
Sbjct: 37  ASPSASGASIPSDS---GWASPSASGASTPSNSGWASFSASWASIPSDSGWASPSA-SWA 92

Query: 328 GDPGAP--LTPRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGS 385
             P      +P  +  S P+    +SP + +G S  S     P    S  +    SG  S
Sbjct: 93  STPSDSGWASPSASGASIPSDSGWASPSV-SGASIPSAFWASPS--ASGASTPSDSGWAS 149

Query: 386 PSAS-----RGSNWGE-SFSWHCCTATAAALLLQRGDSSASGGAAGPPLSGSSPSAS 436
           PSAS       S W   S SW   +A+ A+       + +  G A P +   SPS S
Sbjct: 150 PSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSDSGWASPSVFWVSPSTS 206



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 85/326 (26%), Positives = 104/326 (31%), Gaps = 95/326 (29%)

Query: 108 GLLGGSPGAAG-GRGGH--------GLEGTAPALPLR-------GGRSRGWLF------- 144
           GL  G+ G    G GGH        GL GT   LPLR        G + GWL        
Sbjct: 522 GLFDGTSGCPHCGLGGHRAHFLPHAGLAGTE-LLPLRLLAQLAPQGCAEGWLVLQGEGEG 580

Query: 145 ----APVRLPSEL---PFGTGAGLGLWARSGGNAPVEGCPRRFHF--------------- 182
                P+R   E+   P    A LGL  +     P EG P R                  
Sbjct: 581 PQAQGPLREGREVSQAPETVSALLGLQEQ----LPGEGLPWRLQHHPTRPALELLELSLG 636

Query: 183 --LFRRGVIAGRVWRHLVVEHRVVPGSALRELGVRAGGVG--GFLRPPPPPRPTAAGPLL 238
             L   G +  ++ RHLV +  V+   A  EL  R G VG  G LR    P   A G LL
Sbjct: 637 AVLEALGHVLLQLGRHLVQQIIVLQAPACSELSHRTGKVGQEGLLRLLQVP-SMAQGTLL 695

Query: 239 HVVPVTAIFRSGSNHD------------RLVHLCPLSLTQSACAELAVCAAPSAGGSPGK 286
              P   +  S    D            R   +   S  Q     L + A     G P  
Sbjct: 696 SPEPPEPLLMSTPEEDVGVKFSVMAWDPRSFEMLSSSWYQGESLNLTLLA-----GDPRS 750

Query: 287 SDAPLRGWLRALRGPRE---------PSSAHTLGAP-----------LGASPSPPAGRSW 326
           S    R   + +R P E          +S   LG P           + A   P + R  
Sbjct: 751 SSNNCRLARQVMRAPAEQLSLLAMGLDTSGTLLGRPCLEPISALMICVEADTRPGSARRL 810

Query: 327 VGDPGAPLTPRKASCSWPAPGEASSP 352
              P     P   S  W +PG  S P
Sbjct: 811 TLQPAGASLP---SREWSSPGSTSGP 833


>gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]
          Length = 903

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 66/237 (27%), Positives = 93/237 (39%), Gaps = 47/237 (19%)

Query: 274 VCAAPSAGGSPGKSDAPLRGWLRALRGP--REPSSAHTLGAPLGASPSPPAGRSWVGDP- 330
           VC A    G   +S  P+    + + GP   EP++A    AP      P AG    G P 
Sbjct: 375 VCQASQLQGQKEESCVPVHQ--KTVLGPDTAEPATAEAAVAP------PDAGLPLPGLPA 426

Query: 331 -GAPLTPRKASCS---WPAPGEASSPGLRAG-VSAFSCL------EEFPG------EECS 373
            G+P      SC      +P + S P + A  +S  SCL      EE P       E+ +
Sbjct: 427 EGSPPPKTYVSCLKSLLSSPTKDSKPNISAHHISLASCLALTTPSEELPDRAGILVEDAT 486

Query: 374 CLAVVVASGKGSPSASRGSNWGESFSWH----CCTATAAALLLQRGDSSASGGAAGPPLS 429
           C+  +  S +  P  +   +  +SFS       CT T+         SS    A  PPL 
Sbjct: 487 CVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETS---------SSPRDKAITPPLP 537

Query: 430 GSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMK 486
            S+   S G  +GE S L      G ED       A  S  + R+ + S  S C++K
Sbjct: 538 ESTVPFSNGVLKGELSDL------GAEDGWTMDAEADHSGGSDRNSMDSVDSCCSLK 588


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 99/393 (25%), Positives = 127/393 (32%), Gaps = 64/393 (16%)

Query: 278  PSAGGSPGKSDAPLRGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAP-LTP 336
            P A G PG    P         GP  PS     G+P    P  PAG +  G PG+P ++ 
Sbjct: 869  PGAAGFPGARGLPGPPGSNGNPGPPGPS-----GSPGKDGPPGPAGNT--GAPGSPGVSG 921

Query: 337  RKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSAS---RGSN 393
             K       PGE  SPG +    A       PG       +  A G   P      RGS 
Sbjct: 922  PKGDAG--QPGEKGSPGAQGPPGA-------PGP-LGIAGITGARGLAGPPGMPGPRGSP 971

Query: 394  WGESFSWHCCTATAAALLLQRGDSSASG-----GAAGPPLSGSSPSASRGFSRGEPSSLV 448
              +          A  L  +RG     G     G AG P    +P      S G P    
Sbjct: 972  GPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPG-----SDGLPGRDG 1026

Query: 449  SVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALAGAPMGG 508
            S   +G   E   P      +     H G              G S   GPA A  P G 
Sbjct: 1027 SPGGKGDRGENGSP-----GAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG- 1080

Query: 509  ARERSNTRVIPRLQSASERLLPSRG--GVVEGCAWDSAYSAPG-PVPRHTCGSGVARLEP 565
                S     P+     +     RG  G+     +     APG P P    G+ +    P
Sbjct: 1081 ----SRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGA-IGSPGP 1135

Query: 566  QGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRREGAQNKPIKANPP- 624
             GP      +GPP  D       G PG +  PG +    +   R  EG+   P +  PP 
Sbjct: 1136 AGPRGPVGPSGPPGKDGT----SGHPGPIGPPGPR---GNRGERGSEGSPGHPGQPGPPG 1188

Query: 625  -----------MGAVALRGLPEWGLATGAPFRG 646
                       +GA A+ G+        AP+ G
Sbjct: 1189 PPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYG 1221



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 84/350 (24%), Positives = 108/350 (30%), Gaps = 51/350 (14%)

Query: 282 GSPGKSDAPLRGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAP--LTPRKA 339
           G+PG+   P    L    G R    A       G  P PP    + G PGA   + P  +
Sbjct: 303 GAPGERGRP---GLPGAAGARGNDGARGSDGQPGP-PGPPGTAGFPGSPGAKGEVGPAGS 358

Query: 340 SCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFS 399
             S  APG+   PG +    A                     G   P    GS  G+   
Sbjct: 359 PGSNGAPGQRGEPGPQGHAGA--------------------QGPPGPPGINGSPGGKGEM 398

Query: 400 WHCCTATAAALLLQRGDSSASGGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEE 459
                  A  L+  RG    +G    P L G +    +  ++GEP        RG+  E 
Sbjct: 399 GPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGP------RGERGEA 452

Query: 460 KKP-VLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALA-GAP--MGGARERSNT 515
             P V  A          G   +        + G     GPA   G P   G A ER   
Sbjct: 453 GIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAP 512

Query: 516 RVIPRLQSASERLLPSRGGVVEGCAWDSAYSAPGPVPRHTCGSGV-ARLEPQGPAHLCEG 574
                  +A E   P R GV  G        +PG       G G   +  P G       
Sbjct: 513 GPAGPRGAAGE---PGRDGVPGGPGMRGMPGSPG-------GPGSDGKPGPPGSQGESGR 562

Query: 575 AGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRREGAQNKPIKANPP 624
            GPP     R    G+PG++  PG K    +       G    P    PP
Sbjct: 563 PGPPGPSGPR----GQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPP 608



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 102/420 (24%), Positives = 131/420 (31%), Gaps = 77/420 (18%)

Query: 268 ACAELAVCAAPSAGGSPGKSDAPLRGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWV 327
           A  E+    +P + G+PG+   P         GP+  + A     P G + S P G+  +
Sbjct: 349 AKGEVGPAGSPGSNGAPGQRGEP---------GPQGHAGAQGPPGPPGINGS-PGGKGEM 398

Query: 328 GDPGAPLTPRKASCSWPAPGEA---SSPGLR--AGVSAFSCLEEFPGE-----ECSCLAV 377
           G  G P  P       P PG A    +PGLR  AG    +  +  PG      E     V
Sbjct: 399 GPAGIPGAPGLMGARGP-PGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGV 457

Query: 378 VVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSASG--GAAGPPLSGSSPSA 435
             A G+     S G               A  L    G+  A G  G AGP  +G     
Sbjct: 458 PGAKGEDGKDGSPGE------------PGANGLPGAAGERGAPGFRGPAGP--NGIPGEK 503

Query: 436 SRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSK 495
                RG P         G+   +  P       R +    G   S          G S 
Sbjct: 504 GPAGERGAPGPAGPRGAAGEPGRDGVP--GGPGMRGMPGSPGGPGSDGKPGPPGSQGESG 561

Query: 496 HLGPALAGAPMG--------------GARERSNTRVIPRLQSASERLLPSRGGVVEGCAW 541
             GP     P G              GA  ++  R  P       +  P + G       
Sbjct: 562 RPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGP--GGPGPQGPPGKNGET----- 614

Query: 542 DSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKR 601
                 PGP              PQG   L    GPP        E GKPG    PG K 
Sbjct: 615 -GPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG-------ENGKPG---EPGPKG 663

Query: 602 LASSARARRREGAQNKPIKANPP--MGAVALRGLPEWGLATGAPFRGRGGSAATREPQSA 659
            A +  A   +G    P +  PP   GA  LRG    G     P  G+G +     P +A
Sbjct: 664 DAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRG----GAGPPGPEGGKGAAGPPGPPGAA 719



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 97/388 (25%), Positives = 119/388 (30%), Gaps = 60/388 (15%)

Query: 277 APSAGGSPGKSDAPLRGWLRALRGPREPSSAHTLGAPLGASP-SPPAGRSWVGDPGAPLT 335
           AP A G  G + AP        RGP  P  A   G   GA P  P  G+   G PG    
Sbjct: 667 APGAPGGKGDAGAP------GERGP--PGLAGAPGLRGGAGPPGPEGGKGAAGPPG---- 714

Query: 336 PRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPS--ASRGSN 393
                     PG A +PGL+            PGE     +      KG P    + G  
Sbjct: 715 ---------PPGAAGTPGLQG----------MPGERGGLGSPGPKGDKGEPGGPGADGVP 755

Query: 394 WGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFR 453
             +                Q GD    G    P ++G  P  S G  RGE        F 
Sbjct: 756 GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAG--PRGSPG-ERGETGPPGPAGFP 812

Query: 454 GKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALAGAPMGGARERS 513
           G   +  +P       +  R   G              GGS   GPA    P G   ER 
Sbjct: 813 GAPGQNGEP-----GGKGERGAPGEKGEGGPPGVAGPPGGS---GPAGPPGPQGVKGERG 864

Query: 514 NTRVIPRLQSASERLLPSRGGVVEGCAWDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCE 573
           +            R LP   G           S   P P    GS   +  P GPA    
Sbjct: 865 SPGGPGAAGFPGARGLPGPPG-----------SNGNPGPPGPSGS-PGKDGPPGPAGNTG 912

Query: 574 GAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRREGAQNKPIKANPPMGAVALRGL 633
             G P     +  + G+PG   SPGA+    +       G       A PP G    RG 
Sbjct: 913 APGSPGVSGPKG-DAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPP-GMPGPRGS 970

Query: 634 P-EWGLATGAPFRGRGGSAATREPQSAQ 660
           P   G+   +   G  G +  R P   Q
Sbjct: 971 PGPQGVKGESGKPGANGLSGERGPPGPQ 998


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 81/335 (24%), Positives = 115/335 (34%), Gaps = 71/335 (21%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSAGGSP 284
           P PPPR + AGP++ V P   +  + S    LV   P     +     A  +AP+   +P
Sbjct: 21  PSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLV--APGEARPAWVPGSAETSAPAPAPAP 78

Query: 285 GKSDAPLRGWLRAL--------------RGPREPSSAHTLGAPLG--------------A 316
             + A     +  L               GP  P  A   G                  A
Sbjct: 79  APAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAGADSPKTEEA 138

Query: 317 SPSPPAGRSWVGDPGAPLTPRKASCSWPAPGE-------ASSPG--LRAGVSAFSCLEEF 367
            PSP  G      PG P      + S  APG        A  PG  + +GV+A S   + 
Sbjct: 139 RPSPAPG------PGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGVTARSASGQV 192

Query: 368 PGEECSCLAVVVASGKGSPSASRGSNWGESFSWHC----CTATAAALLLQRGDSSASGGA 423
            G   +  A   ++G+ +P    G   G S +        T T A    +      S  +
Sbjct: 193 TGGHGAAAATSASAGQ-APEDPSGPGTGPSGTCEAPVAVVTVTPAPEPAENSQDLGSTSS 251

Query: 424 AGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTC 483
            GP +SG    A    S  +  SL+S       D+               S +GS  S  
Sbjct: 252 LGPGISGPRGQAPDTLSYLDSVSLMSGTLESLADDV--------------SSMGS-DSEI 296

Query: 484 NMKTLSK------LGGSKHLGPALAGAPMGGARER 512
           N   L K      LGGS++ G   +  P+  AR+R
Sbjct: 297 NGLALRKTDKYGFLGGSQYSGSLESSIPVDVARQR 331


>gi|148886696 surfactant protein A2 [Homo sapiens]
          Length = 248

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 37/106 (34%), Positives = 47/106 (44%), Gaps = 15/106 (14%)

Query: 259 LCPLSLTQ-------SACAELAVCA-APSAGGSPGKSDAPLRGWLRALRGPREPSSAHTL 310
           LCPL+LT        +AC    VC  +P   G+PG    P R     ++G  +P     +
Sbjct: 3   LCPLALTLILMAASGAACEVKDVCVGSPGIPGTPGSHGLPGRDGRDGVKG--DPGPPGPM 60

Query: 311 GAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRA 356
           G P G +P PP      G PGAP  P +      A GE   PGL A
Sbjct: 61  GPP-GETPCPPGNN---GLPGAPGVPGERGEKGEA-GERGPPGLPA 101


>gi|146149162 surfactant, pulmonary-associated protein A2 [Homo
           sapiens]
          Length = 248

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 37/106 (34%), Positives = 47/106 (44%), Gaps = 15/106 (14%)

Query: 259 LCPLSLTQ-------SACAELAVCA-APSAGGSPGKSDAPLRGWLRALRGPREPSSAHTL 310
           LCPL+LT        +AC    VC  +P   G+PG    P R     ++G  +P     +
Sbjct: 3   LCPLALTLILMAASGAACEVKDVCVGSPGIPGTPGSHGLPGRDGRDGVKG--DPGPPGPM 60

Query: 311 GAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRA 356
           G P G +P PP      G PGAP  P +      A GE   PGL A
Sbjct: 61  GPP-GETPCPPGNN---GLPGAPGVPGERGEKGEA-GERGPPGLPA 101


>gi|122692281 hypothetical protein LOC645369 [Homo sapiens]
          Length = 621

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 93/396 (23%), Positives = 135/396 (34%), Gaps = 72/396 (18%)

Query: 267 SACAELAVCAAPSAGGSPGKSDA---PLRGWLRALRG---PREPSSAHTLGAPLGASPSP 320
           +A A  A  AA S+  +P  +     PL G+L  ++      +P      G   GA+   
Sbjct: 220 AAAAAAAAAAASSSSSAPAAAPPGAIPLNGFLSYVQSRGLELKPGGCGGSGDAFGAAAML 279

Query: 321 PAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGL-----RAGVSAFSCLEEFPG-----E 370
             G SW   P AP   R    + P P  ASSP           + +S   E  G      
Sbjct: 280 AKG-SWPPHPAAPSGGRPRGAASP-PDLASSPRCPREPPSLAEAVYSVYRERSGVAGSRR 337

Query: 371 ECSCLAVVVASGKGSPS-ASRGSNWGE---SFSWHCCTATAAALLLQRGDSSASGGAAGP 426
             +  A   AS   SP+  S   +WG    + S+   + +A ALL  +G     G A G 
Sbjct: 338 AAAATAAAAASSCSSPAPCSPPESWGRQSTASSFVDSSLSAFALLPLQGGRDRGGDAEGA 397

Query: 427 PLSGSSPSASRG---FSRGEPSSLVSVCFRG---------KEDEEKKPVLAAFSSRTVRS 474
             S   P   RG     RGE   L     RG         +E EE +  +AA ++R    
Sbjct: 398 SCSWQRPPGERGSQEIPRGE-LDLSMTNLRGAEGSMRGARREPEEPEGAVAARAARGQGG 456

Query: 475 HLGSTSSTCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGG 534
            L  T     ++  S  G   +  P     P                        PS G 
Sbjct: 457 RLPRTGRYAALRRRSTSGLPDYRAPPSPEPP------------------------PSPG- 491

Query: 535 VVEGCAWDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLL 594
                   SA     P+ +    S   RLE   P     G+   ++DP  S +G  P   
Sbjct: 492 --------SADPDSSPLAKAASPSPPLRLEGSPPTRRDSGSS-QSDDPSSSNKGYTPLRE 542

Query: 595 ISPGAKRLASSARARRREGAQNKPI---KANPPMGA 627
                + +  +   + R+ A   P+   + + P GA
Sbjct: 543 AGTSTESVLDAVAGQTRDSAVAAPVLGAEQSSPEGA 578


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 42/155 (27%), Positives = 60/155 (38%), Gaps = 20/155 (12%)

Query: 299 RGPREPSSAHTLGAPLGASPSPPAGRSW-----VGDPGAPLTP-----RKASCSWPAPGE 348
           +GP      +  G+P   +P PP G  W      G P  P  P     R  S S P P E
Sbjct: 667 QGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTE 726

Query: 349 ASSPGLRAG-----VSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCC 403
             + G   G     + +++ L   PG      A+V  S   +P+ +RG+   +SF+    
Sbjct: 727 GDAEGEAEGPVGSTLGSYATLTRRPGRS----ALVRTSPSVTPTPARGTPRSQSFALRAR 782

Query: 404 TATAAALLLQRGDSSASGGAAGPPLSGSSPSASRG 438
                    +R  SS SG +  PP    SP    G
Sbjct: 783 RKGPPPPPPKR-LSSVSGPSPEPPPLDESPGPKEG 816



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 54/178 (30%), Positives = 63/178 (35%), Gaps = 18/178 (10%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSA--GG 282
           PP PPRP      L     T     G          P+  T  + A L      SA    
Sbjct: 706 PPDPPRPKRRSHSLSRPGPTEGDAEGEAEG------PVGSTLGSYATLTRRPGRSALVRT 759

Query: 283 SPGKSDAPLRGW-------LRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLT 335
           SP  +  P RG        LRA R    P     L +  G SP PP      G       
Sbjct: 760 SPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATG 819

Query: 336 PRKASCSWPA-PGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGS 392
           PR+ + S PA P E   P   AG  A    EE PG E        +SG+G P A  G+
Sbjct: 820 PRRRTLSEPAGPSEPPGPPAPAG-PASDTEEEEPGPE-GTPPSRGSSGEGLPFAEEGN 875


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 42/155 (27%), Positives = 60/155 (38%), Gaps = 20/155 (12%)

Query: 299 RGPREPSSAHTLGAPLGASPSPPAGRSW-----VGDPGAPLTP-----RKASCSWPAPGE 348
           +GP      +  G+P   +P PP G  W      G P  P  P     R  S S P P E
Sbjct: 749 QGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTE 808

Query: 349 ASSPGLRAG-----VSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCC 403
             + G   G     + +++ L   PG      A+V  S   +P+ +RG+   +SF+    
Sbjct: 809 GDAEGEAEGPVGSTLGSYATLTRRPGRS----ALVRTSPSVTPTPARGTPRSQSFALRAR 864

Query: 404 TATAAALLLQRGDSSASGGAAGPPLSGSSPSASRG 438
                    +R  SS SG +  PP    SP    G
Sbjct: 865 RKGPPPPPPKR-LSSVSGPSPEPPPLDESPGPKEG 898



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 54/178 (30%), Positives = 63/178 (35%), Gaps = 18/178 (10%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAAPSA--GG 282
           PP PPRP      L     T     G          P+  T  + A L      SA    
Sbjct: 788 PPDPPRPKRRSHSLSRPGPTEGDAEGEAEG------PVGSTLGSYATLTRRPGRSALVRT 841

Query: 283 SPGKSDAPLRGW-------LRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLT 335
           SP  +  P RG        LRA R    P     L +  G SP PP      G       
Sbjct: 842 SPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATG 901

Query: 336 PRKASCSWPA-PGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGS 392
           PR+ + S PA P E   P   AG  A    EE PG E        +SG+G P A  G+
Sbjct: 902 PRRRTLSEPAGPSEPPGPPAPAG-PASDTEEEEPGPE-GTPPSRGSSGEGLPFAEEGN 957


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 61/220 (27%), Positives = 76/220 (34%), Gaps = 56/220 (25%)

Query: 211 ELGVRAGGVGGFLRPPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACA 270
           ELG R   VG F  PPPPP+ T+A                      +     +   S C 
Sbjct: 706 ELGQR---VGLFPPPPPPPQVTSA----------------------IATLQQAAAMSFCP 740

Query: 271 ELA-VCAAPSAGGSPGKSDAPLRGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGD 329
           ++A     P A GSP     P  G   A   P  P  A   GAP  ASP  P    + G 
Sbjct: 741 QVARPLVGPLALGSPRLVRRPPPGPAPAAASPGPPPPASPPGAP--ASPRAPRTSPYGGL 798

Query: 330 PGAPLT----PRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGS 385
           P APL     P +       P  AS P L  G          PG   S      ++ +  
Sbjct: 799 PAAPLAGPALPARRLSRASRPLSASQPSLPHGA---------PGPAASTRPASSSTPRLG 849

Query: 386 PSASRGSNWGESFSWHCCTATAAALLLQRGDSSASGGAAG 425
           P+ +               A AAA    R DS++ G A G
Sbjct: 850 PTPA---------------ARAAAPSPDRRDSASPGAAGG 874



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 37/139 (26%), Positives = 47/139 (33%), Gaps = 35/139 (25%)

Query: 560 VARLEPQGPAHLCEGAGPP-----------ANDPQRSQEGGKPGLLISPGAKRLASSARA 608
           + R  P GPA      GPP              P+ S  GG P       A  LA  A  
Sbjct: 757 LVRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLP-------AAPLAGPALP 809

Query: 609 RRREGAQNKPIKANPPMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQRNRLRVTH 668
            RR    ++P+ A+ P             L  GAP     G AA+  P S+   RL  T 
Sbjct: 810 ARRLSRASRPLSASQP------------SLPHGAP-----GPAASTRPASSSTPRLGPTP 852

Query: 669 PPESAPEEVRMNQICSQGS 687
              +A          S G+
Sbjct: 853 AARAAAPSPDRRDSASPGA 871


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 43/167 (25%), Positives = 58/167 (34%), Gaps = 14/167 (8%)

Query: 492 GGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVVEGCAWDSAYSAPGPV 551
           GG+K  GP   G P G   +  N     R      +  P +GG              GP 
Sbjct: 146 GGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 205

Query: 552 PRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRR 611
           P+          +PQGP    +  GPP     +SQ    P     PG  +        + 
Sbjct: 206 PQ-------GGNKPQGPPPPGKPQGPPPQGDNKSQSARSP-----PGKPQGPPPQGGNQP 253

Query: 612 EGAQNKPIKAN--PPMGAVALRGLPEWGLATGAPFRGRGGSAATREP 656
           +G    P K    PP G    +G P  G   G P +G   S ++R P
Sbjct: 254 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 42/167 (25%), Positives = 59/167 (35%), Gaps = 15/167 (8%)

Query: 492 GGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVVEGCAWDSAYSAPGPV 551
           GG+K  GP   G P G   +   +R  PR      +  P +GG       +     P P 
Sbjct: 85  GGNKPQGPPPPGKPQGPPPQGDKSR-SPRSPPGKPQGPPPQGG-------NQPQGPPPPP 136

Query: 552 PRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRR 611
            +          +PQGP    +  GPP     +S+    P     PG  +        + 
Sbjct: 137 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP-----PGKPQGPPPQGGNQP 191

Query: 612 EGAQNKPIKAN--PPMGAVALRGLPEWGLATGAPFRGRGGSAATREP 656
           +G    P K    PP G    +G P  G   G P +G   S + R P
Sbjct: 192 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 42/167 (25%), Positives = 57/167 (34%), Gaps = 14/167 (8%)

Query: 492 GGSKHLGPALAGAPMGGARERSNTRVIPRLQSASERLLPSRGGVVEGCAWDSAYSAPGPV 551
           GG+K  GP   G P G   +  N     R      +  P +GG              GP 
Sbjct: 208 GGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 267

Query: 552 PRHTCGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRR 611
           P+          +PQGP    +  GPP     +S+    P     PG  +        + 
Sbjct: 268 PQ-------GGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP-----PGKPQGPPPQGGNQP 315

Query: 612 EGAQNKPIKAN--PPMGAVALRGLPEWGLATGAPFRGRGGSAATREP 656
           +G    P K    PP G    +G P  G   G P +G   S + R P
Sbjct: 316 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP 362


>gi|27437008 kringle-containing transmembrane protein 2 isoform d
           precursor [Homo sapiens]
          Length = 462

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 56/178 (31%), Positives = 66/178 (37%), Gaps = 31/178 (17%)

Query: 282 GSPGKSDAPLR-GWLRALRGPREPSSAHTLGAPL------GASPSPPAGRSWVGDPGAPL 334
           G+      PLR G    L   R  +  H  G  L       A+  P A       P APL
Sbjct: 288 GARPPPSGPLRLGTAALLLTFRSDARGHAQGFALTYRGLQDAAEDPEAPEGSAQTPAAPL 347

Query: 335 TPRKASCSWPAPGEASSPGLRAGVSAFSCLEEF------------PGEECSCLAVVVASG 382
                SCS P PG   +P    G   FS +               P    SCL   +A G
Sbjct: 348 DGANVSCS-PRPG---APPAAIGARVFSTVTAVSVLLLLLLGLLRPLRRRSCL---LAPG 400

Query: 383 KGSPSASRGSNWGESFSWHCC--TATAAALLLQRGDSSASGGAAG-PPLSGSSPSASR 437
           KG P+   G++ G   SW          AL    GD  A G AAG  PLS SS S+ R
Sbjct: 401 KGPPAL--GASRGPRRSWAVWYQQPRGVALPCSPGDPQAEGSAAGYRPLSASSQSSLR 456


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 68/248 (27%), Positives = 93/248 (37%), Gaps = 44/248 (17%)

Query: 419 ASGGAAGPPLSGSSPSASRGFSRGEPSSLVSVC----FRGKED-------EEKKPVLAAF 467
           A  G   PPL G     +RG     P  +V +       G++D       E   P LA  
Sbjct: 210 AGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERLSPFLA-- 267

Query: 468 SSRTVRSHLG-STSSTCNMKTLSKLGGSKHLG-PAL-AGAPMGGARERSNTRVIPRLQSA 524
            S+T  + L  S  + CN       GG+  +G PAL A A  GGA+E +      RL   
Sbjct: 268 ESKTKNAALQPSVLTMCN-------GGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRR 320

Query: 525 SERLLPSRGGVVEGCAWDSAYSAPGPVPRHTCGSGVARL-EPQGPAH------------- 570
           +E LLP             A     P P     +GV  +   QG  H             
Sbjct: 321 TETLLPGPRPCPSPLPPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEA 380

Query: 571 LCEGAGP-----PANDPQ-RSQEGGKPGLL-ISPGAKRLASSARARRREGAQNKPIKANP 623
             E  GP      A D + R +E G+PG+L   PG+ R        R + +  + +K  P
Sbjct: 381 FDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPP 440

Query: 624 PMGAVALR 631
           P  A  +R
Sbjct: 441 PADAPTVR 448



 Score = 33.5 bits (75), Expect = 0.70
 Identities = 65/281 (23%), Positives = 94/281 (33%), Gaps = 35/281 (12%)

Query: 278  PSAGGSPGKSDAPLRGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPR 337
            P AGG          G      G  EP +          +  P  G ++  D G P +P 
Sbjct: 2487 PGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFE-DSGNPKSPD 2545

Query: 338  KASCSWPAPGEA------SSPGLRAGVSAFSCLEEFPGEE----------------CSCL 375
            KA        E+      SS    +  S+ S   E  GEE                CS  
Sbjct: 2546 KAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAA 2605

Query: 376  AVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSGSSPSA 435
            +   AS   S S+S  S+   S S    ++++++       SS+S  ++    S SS S+
Sbjct: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSS-----SSSSSSSSSSSSSSSSSSSSS 2660

Query: 436  SRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSK 495
            S   S    SS          D+E  P   A  S        +T      K   K   S 
Sbjct: 2661 SSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKAT------KQAGKARPSA 2714

Query: 496  HLGPALAGAPMGGARERSNTRVI-PRLQSASERLLPSRGGV 535
            H       AP   A     T+ + P+ Q+ ++     R GV
Sbjct: 2715 HSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGV 2755


>gi|147903070 surfactant protein A1 [Homo sapiens]
          Length = 245

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 35/107 (32%), Positives = 43/107 (40%), Gaps = 17/107 (15%)

Query: 259 LCPLSL-------TQSACAELAVCA-APSAGGSPGKSDAPLRGWLRALRGPREPSSAHTL 310
           LCPL+L       + + C    VC  +P   G+PG    P R     L+G  +P     +
Sbjct: 3   LCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKG--DPGPPGPM 60

Query: 311 GAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPA-PGEASSPGLRA 356
           G P G  P PP      G PG P       C     PGE   PGL A
Sbjct: 61  GPP-GEMPCPPGNDGLPGAPGIP-----GECGEKGEPGERGPPGLPA 101


>gi|38888175 surfactant, pulmonary-associated protein A1B [Homo
           sapiens]
          Length = 248

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 35/107 (32%), Positives = 43/107 (40%), Gaps = 17/107 (15%)

Query: 259 LCPLSL-------TQSACAELAVCA-APSAGGSPGKSDAPLRGWLRALRGPREPSSAHTL 310
           LCPL+L       + + C    VC  +P   G+PG    P R     L+G  +P     +
Sbjct: 3   LCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKG--DPGPPGPM 60

Query: 311 GAPLGASPSPPAGRSWVGDPGAPLTPRKASCSWPA-PGEASSPGLRA 356
           G P G  P PP      G PG P       C     PGE   PGL A
Sbjct: 61  GPP-GEMPCPPGNDGLPGAPGIP-----GECGEKGEPGERGPPGLPA 101


>gi|15826862 coiled-coil domain containing 120 isoform 3 [Homo
           sapiens]
          Length = 630

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 114/454 (25%), Positives = 155/454 (34%), Gaps = 95/454 (20%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSG--SNHDRLVHLCPLSLTQSACAELAVCAAPSAGG 282
           P P P P + G ++    V    R    S  D ++H    SL++S  +       P    
Sbjct: 177 PLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSESSSLSESGASHDN--EEPHGCF 234

Query: 283 SPGKSDAPLRGW--LRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLT--PRK 338
           S  +  +P + W  LRA+ G            P        + R+ V  P +P    PR 
Sbjct: 235 SLAERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRS 294

Query: 339 ASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESF 398
           AS S+      ++P L  G     C  E  G      +    S  G P A   S+    F
Sbjct: 295 AS-SFEGRSVPATPVLTRGAGPQLCKPE--GLHSRQWSGSQDSQMGFPRADPASDRASLF 351

Query: 399 SWHCCTATAA-ALLLQRGDSSASGGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKED 457
                 + ++ ALL+ R    A+GG AG P +  +PSAS     G P     VC   +  
Sbjct: 352 VARTRRSNSSEALLVDR----AAGGGAGSPPAPLAPSAS-----GPP-----VCKSSEVL 397

Query: 458 EEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRV 517
            E+     AFSSR           T       +        PA  GAP          R+
Sbjct: 398 YERPQPTPAFSSR-----------TAGPPDPPRAARPSSAAPASRGAP----------RL 436

Query: 518 IP-----RLQSASERLLPSRGGVVEGCAWDSAYSA-----------------PGPVPRHT 555
            P      L  + +R LP  GG   G  W     A                 PGP P + 
Sbjct: 437 PPVCGDFLLDYSLDRGLPRSGG---GTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYA 493

Query: 556 CGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGK---PGLLISPGAKRLASSARARRRE 612
             S    L  + P H       P   P  + EG +     LL  P   R+ S   A  R 
Sbjct: 494 ADSNSPLLRTKDP-HTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPS---AGERS 549

Query: 613 GAQNKPIKANPPMGAVALRGLPEW-----GLATG 641
           G +N           +AL GL +W     GLA G
Sbjct: 550 GHKN-----------LALEGLRDWYIRNSGLAAG 572


>gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo
           sapiens]
          Length = 618

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 114/454 (25%), Positives = 155/454 (34%), Gaps = 95/454 (20%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSG--SNHDRLVHLCPLSLTQSACAELAVCAAPSAGG 282
           P P P P + G ++    V    R    S  D ++H    SL++S  +       P    
Sbjct: 165 PLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSESSSLSESGASHDN--EEPHGCF 222

Query: 283 SPGKSDAPLRGW--LRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLT--PRK 338
           S  +  +P + W  LRA+ G            P        + R+ V  P +P    PR 
Sbjct: 223 SLAERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRS 282

Query: 339 ASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESF 398
           AS S+      ++P L  G     C  E  G      +    S  G P A   S+    F
Sbjct: 283 AS-SFEGRSVPATPVLTRGAGPQLCKPE--GLHSRQWSGSQDSQMGFPRADPASDRASLF 339

Query: 399 SWHCCTATAA-ALLLQRGDSSASGGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKED 457
                 + ++ ALL+ R    A+GG AG P +  +PSAS     G P     VC   +  
Sbjct: 340 VARTRRSNSSEALLVDR----AAGGGAGSPPAPLAPSAS-----GPP-----VCKSSEVL 385

Query: 458 EEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRV 517
            E+     AFSSR           T       +        PA  GAP          R+
Sbjct: 386 YERPQPTPAFSSR-----------TAGPPDPPRAARPSSAAPASRGAP----------RL 424

Query: 518 IP-----RLQSASERLLPSRGGVVEGCAWDSAYSA-----------------PGPVPRHT 555
            P      L  + +R LP  GG   G  W     A                 PGP P + 
Sbjct: 425 PPVCGDFLLDYSLDRGLPRSGG---GTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYA 481

Query: 556 CGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGK---PGLLISPGAKRLASSARARRRE 612
             S    L  + P H       P   P  + EG +     LL  P   R+ S   A  R 
Sbjct: 482 ADSNSPLLRTKDP-HTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPS---AGERS 537

Query: 613 GAQNKPIKANPPMGAVALRGLPEW-----GLATG 641
           G +N           +AL GL +W     GLA G
Sbjct: 538 GHKN-----------LALEGLRDWYIRNSGLAAG 560


>gi|254039612 coiled-coil domain containing 120 isoform 2 [Homo
           sapiens]
          Length = 649

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 114/454 (25%), Positives = 155/454 (34%), Gaps = 95/454 (20%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSG--SNHDRLVHLCPLSLTQSACAELAVCAAPSAGG 282
           P P P P + G ++    V    R    S  D ++H    SL++S  +       P    
Sbjct: 165 PLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSESSSLSESGASHDN--EEPHGCF 222

Query: 283 SPGKSDAPLRGW--LRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLT--PRK 338
           S  +  +P + W  LRA+ G            P        + R+ V  P +P    PR 
Sbjct: 223 SLAERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRS 282

Query: 339 ASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESF 398
           AS S+      ++P L  G     C  E  G      +    S  G P A   S+    F
Sbjct: 283 AS-SFEGRSVPATPVLTRGAGPQLCKPE--GLHSRQWSGSQDSQMGFPRADPASDRASLF 339

Query: 399 SWHCCTATAA-ALLLQRGDSSASGGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKED 457
                 + ++ ALL+ R    A+GG AG P +  +PSAS     G P     VC   +  
Sbjct: 340 VARTRRSNSSEALLVDR----AAGGGAGSPPAPLAPSAS-----GPP-----VCKSSEVL 385

Query: 458 EEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRV 517
            E+     AFSSR           T       +        PA  GAP          R+
Sbjct: 386 YERPQPTPAFSSR-----------TAGPPDPPRAARPSSAAPASRGAP----------RL 424

Query: 518 IP-----RLQSASERLLPSRGGVVEGCAWDSAYSA-----------------PGPVPRHT 555
            P      L  + +R LP  GG   G  W     A                 PGP P + 
Sbjct: 425 PPVCGDFLLDYSLDRGLPRSGG---GTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYA 481

Query: 556 CGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGK---PGLLISPGAKRLASSARARRRE 612
             S    L  + P H       P   P  + EG +     LL  P   R+ S   A  R 
Sbjct: 482 ADSNSPLLRTKDP-HTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPS---AGERS 537

Query: 613 GAQNKPIKANPPMGAVALRGLPEW-----GLATG 641
           G +N           +AL GL +W     GLA G
Sbjct: 538 GHKN-----------LALEGLRDWYIRNSGLAAG 560


>gi|254039610 coiled-coil domain containing 120 isoform 1 [Homo
           sapiens]
          Length = 661

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 114/454 (25%), Positives = 155/454 (34%), Gaps = 95/454 (20%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSG--SNHDRLVHLCPLSLTQSACAELAVCAAPSAGG 282
           P P P P + G ++    V    R    S  D ++H    SL++S  +       P    
Sbjct: 177 PLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSESSSLSESGASHDN--EEPHGCF 234

Query: 283 SPGKSDAPLRGW--LRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLT--PRK 338
           S  +  +P + W  LRA+ G            P        + R+ V  P +P    PR 
Sbjct: 235 SLAERPSPPKAWDQLRAVSGGSPERRTPWKPPPSDLYGDLKSRRNSVASPTSPTRSLPRS 294

Query: 339 ASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESF 398
           AS S+      ++P L  G     C  E  G      +    S  G P A   S+    F
Sbjct: 295 AS-SFEGRSVPATPVLTRGAGPQLCKPE--GLHSRQWSGSQDSQMGFPRADPASDRASLF 351

Query: 399 SWHCCTATAA-ALLLQRGDSSASGGAAGPPLSGSSPSASRGFSRGEPSSLVSVCFRGKED 457
                 + ++ ALL+ R    A+GG AG P +  +PSAS     G P     VC   +  
Sbjct: 352 VARTRRSNSSEALLVDR----AAGGGAGSPPAPLAPSAS-----GPP-----VCKSSEVL 397

Query: 458 EEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALAGAPMGGARERSNTRV 517
            E+     AFSSR           T       +        PA  GAP          R+
Sbjct: 398 YERPQPTPAFSSR-----------TAGPPDPPRAARPSSAAPASRGAP----------RL 436

Query: 518 IP-----RLQSASERLLPSRGGVVEGCAWDSAYSA-----------------PGPVPRHT 555
            P      L  + +R LP  GG   G  W     A                 PGP P + 
Sbjct: 437 PPVCGDFLLDYSLDRGLPRSGG---GTGWGELPPAAEVPGPLSRRDGLLTMLPGPPPVYA 493

Query: 556 CGSGVARLEPQGPAHLCEGAGPPANDPQRSQEGGK---PGLLISPGAKRLASSARARRRE 612
             S    L  + P H       P   P  + EG +     LL  P   R+ S   A  R 
Sbjct: 494 ADSNSPLLRTKDP-HTRATRTKPCGLPPEAAEGPEVHPNPLLWMPPPTRIPS---AGERS 549

Query: 613 GAQNKPIKANPPMGAVALRGLPEW-----GLATG 641
           G +N           +AL GL +W     GLA G
Sbjct: 550 GHKN-----------LALEGLRDWYIRNSGLAAG 572


>gi|169179422 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 645

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 96/365 (26%), Positives = 124/365 (33%), Gaps = 79/365 (21%)

Query: 264 LTQSACAELAVCAAPSAGGSPGKSDAPLRGWLRALRGPREPSS-------AHTLGAPL-G 315
           +    C E A    P  GG  G S   + G    L  P  PSS          L APL  
Sbjct: 283 INMDVCEEPASRTMPYCGGGGG-SQPGVSGGPDTLT-PNSPSSFLPSSFLLCLLPAPLTA 340

Query: 316 ASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLRAGVSAFSC--LEEFPGEECS 373
           A P    GR                    APGE   P L  G+ A SC  + + PG+  +
Sbjct: 341 AQPEDAGGR--------------------APGEEGPPRLAVGLRASSCPIILDPPGKLGT 380

Query: 374 CLAVVVAS-----GKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSASGGAAGPPL 428
            L    A+     G+ SPS  R     E      CTAT  +       +S S    G  L
Sbjct: 381 SLPGPGANSSLREGRTSPSRPRLPQSPEHQQVSACTATWPSCRAAELPASDSPSGWGTWL 440

Query: 429 SGSSP-SASRGFSRGEPSSLVSVCFRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKT 487
           S   P   ++G                K    +   L  + SR   S+L  T   C+ + 
Sbjct: 441 STPPPYKPNKGL---------------KGPTRRSLGLLEWRSRLACSNLLRTGQGCSGQA 485

Query: 488 LSKLGGSKHL-----GPALAGAPMG-----GARERSNTRVIPRLQSASERLLPSRGGVVE 537
           L + G ++ L     G    G P+G     GA  R +   I  L          RG    
Sbjct: 486 LLRCGSNRTLRGGGTGQKWPGVPLGARTGLGAGVRQHPGGIAGLSR-------ERGHSPW 538

Query: 538 GCAWDSAYSA--PGPVPRHTCGSGVARLE-----PQGPAHLCEGAGPPANDPQRSQEGGK 590
               DSA  A  PG VP      G A        P   A   E   PP+  P  ++ GG 
Sbjct: 539 AALTDSAAGAELPGLVPSAPRRPGSATAPRPLRVPGRGAQSAEPGTPPS--PPGAEHGGG 596

Query: 591 PGLLI 595
           PGL++
Sbjct: 597 PGLIL 601


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 106/439 (24%), Positives = 145/439 (33%), Gaps = 71/439 (16%)

Query: 276 AAPSAGGSPGKSDAPLRGWLRALRGPREPSS--AHTLGAPLGASPSPPAGRSWVGDPGAP 333
           A PS   SP  S  PL     A   P+ P++   H L AP    PSPP    +      P
Sbjct: 407 APPSPPASPPLS--PL-----ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 459

Query: 334 LTPRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSN 393
           ++P     S   P  A+ P           L+  P           AS   SPSA+    
Sbjct: 460 VSPSATPPSQAPPSLAAPP-----------LQVPPSPP--------ASPPMSPSATPPPQ 500

Query: 394 WGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSG--SSPSASRGFSRGEPSSLVSVC 451
                +       A  L L +    A    A PPL    S P++  G +   PS+ + + 
Sbjct: 501 APPPLA-------APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 553

Query: 452 FRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALA-----GAPM 506
                  +  PVLAA   +   S   S +     +  +    +   GP L      G P 
Sbjct: 554 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613

Query: 507 GGARERSNTRVIPRL--QSASERLLPSR-GGVVEGCAWDSAYSAPGPVPRHTCGSGVARL 563
             +R  S+T   P L   S+S    P    G   G    +A S P       C       
Sbjct: 614 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 673

Query: 564 EPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRREGAQNKPIKANP 623
            P  P       G P   P  +  G   GL                  EG    P  A P
Sbjct: 674 GPAPPLAFRGAPGAPLPWPPATGPGSADGL------------CTIYETEG----PESATP 717

Query: 624 PMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQRNRLRVTHPPESAPEEVRMNQIC 683
             GA  L   P  G + G    G G  A++R P+ A+   L +     S  + +      
Sbjct: 718 APGA--LDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLL----- 770

Query: 684 SQGSKTLLVLEAPGGRFGT 702
              S+TLL+  A G   G+
Sbjct: 771 ---SRTLLLAAAEGAAGGS 786



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 66/262 (25%), Positives = 87/262 (33%), Gaps = 37/262 (14%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAA----PSA 280
           PPP   P  A PLL V P      +     R     P +        LA+       PS 
Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 617

Query: 281 GGSPGKSDAPLRGWLRALRGPREPSSAHTLGAPLGASPSPPAG--------RSWVGDPGA 332
             S   S   L G   +     E    +  G   GA+ SPP           +W   P  
Sbjct: 618 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 677

Query: 333 PLTPR---KASCSW-PAPGEASSPGL---------RAGVSAFSCLEEFPGEECSCLAVVV 379
           PL  R    A   W PA G  S+ GL          +   A   L+  P    S      
Sbjct: 678 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 737

Query: 380 ASGKGSPSAS-RGSNWGE--------SFSWHCCTAT---AAALLLQRGDSSASGGAAGPP 427
            +G G+ S S + +  GE        S   H  + T   AAA     G     GGA G  
Sbjct: 738 GAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGG 797

Query: 428 LSGSSPSASRGFSRGEPSSLVS 449
           ++G + +A      G  + L+S
Sbjct: 798 VTGGARAALSDAELGRWAELLS 819



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 108/409 (26%), Positives = 143/409 (34%), Gaps = 72/409 (17%)

Query: 312 APLGASPSPPAGRSWVGDPGAPLTPRKASCSWPAPGEASSPGLR----AGVSAFSCLEEF 367
           A  GA+   PA R+    PG  LTPR      P P   +   LR    AG      L E 
Sbjct: 8   AKAGAAARTPAARA----PGL-LTPRPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAER 61

Query: 368 PGEECSCLAVVVASGKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSASGGAAGP- 426
            G       +  ++ +  P+ S G              T++     R  +S  G  A P 
Sbjct: 62  AGG-IGGATIPESAPRAGPTRSAG--------------TSSRNPASRPPASGRGERAPPA 106

Query: 427 ----PLSGSSPSASRGFSRGEPS-------SLVSVCFRGKEDEEKKPVLAAFSSRTVRSH 475
               P   SSP  + G +R  P        S      RGK  E   P  +A S+   R  
Sbjct: 107 KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA--PKRSALSAGARRDT 164

Query: 476 LGSTSSTCN--MKTLSKLGGSKHLGPALAGAPMGGARERSNTRVIPR--LQSASE----- 526
            G T  T +  M   S+  G++   P     P   AR R  T   PR  + SASE     
Sbjct: 165 SGPTPGTPSPAMARRSRAAGTEVGLPR----PAPSARPRPPTEG-PRKSVSSASEHSTTE 219

Query: 527 -----RLLPSRGGVVEGCAWDSAYSAPGPVPRHTCGSGVARLEPQGPAHLCEGAGPPAND 581
                R  PS GG ++  A  S  S+  P+         AR  P+ PAH  +   P    
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-PKPKGLQ 278

Query: 582 PQRSQEGGKPGLLISPGAKRLASSARARRREGAQNKPIKANPPMGAVALRGLPEWGLATG 641
             R  +   P    +P    L+SS  A     A  +  +A P + A          LAT 
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQS-QAPPTLPATPHSSSLTCQLATP 337

Query: 642 APFRGRGGSAATREPQSAQRNRLRVTHPPESAPEEVRMNQICSQGSKTL 690
            P      SA    P S Q     +  PP + P +       S GS TL
Sbjct: 338 LPLAPPSPSA----PPSLQ----TLPSPPATPPSQA----TTSLGSPTL 374


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 106/439 (24%), Positives = 145/439 (33%), Gaps = 71/439 (16%)

Query: 276 AAPSAGGSPGKSDAPLRGWLRALRGPREPSS--AHTLGAPLGASPSPPAGRSWVGDPGAP 333
           A PS   SP  S  PL     A   P+ P++   H L AP    PSPP    +      P
Sbjct: 368 APPSPPASPPLS--PL-----ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 420

Query: 334 LTPRKASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSN 393
           ++P     S   P  A+ P           L+  P           AS   SPSA+    
Sbjct: 421 VSPSATPPSQAPPSLAAPP-----------LQVPPSPP--------ASPPMSPSATPPPQ 461

Query: 394 WGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSG--SSPSASRGFSRGEPSSLVSVC 451
                +       A  L L +    A    A PPL    S P++  G +   PS+ + + 
Sbjct: 462 APPPLA-------APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 514

Query: 452 FRGKEDEEKKPVLAAFSSRTVRSHLGSTSSTCNMKTLSKLGGSKHLGPALA-----GAPM 506
                  +  PVLAA   +   S   S +     +  +    +   GP L      G P 
Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574

Query: 507 GGARERSNTRVIPRL--QSASERLLPSR-GGVVEGCAWDSAYSAPGPVPRHTCGSGVARL 563
             +R  S+T   P L   S+S    P    G   G    +A S P       C       
Sbjct: 575 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 634

Query: 564 EPQGPAHLCEGAGPPANDPQRSQEGGKPGLLISPGAKRLASSARARRREGAQNKPIKANP 623
            P  P       G P   P  +  G   GL                  EG    P  A P
Sbjct: 635 GPAPPLAFRGAPGAPLPWPPATGPGSADGL------------CTIYETEG----PESATP 678

Query: 624 PMGAVALRGLPEWGLATGAPFRGRGGSAATREPQSAQRNRLRVTHPPESAPEEVRMNQIC 683
             GA  L   P  G + G    G G  A++R P+ A+   L +     S  + +      
Sbjct: 679 APGA--LDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLL----- 731

Query: 684 SQGSKTLLVLEAPGGRFGT 702
              S+TLL+  A G   G+
Sbjct: 732 ---SRTLLLAAAEGAAGGS 747



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 66/262 (25%), Positives = 87/262 (33%), Gaps = 37/262 (14%)

Query: 225 PPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLSLTQSACAELAVCAA----PSA 280
           PPP   P  A PLL V P      +     R     P +        LA+       PS 
Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578

Query: 281 GGSPGKSDAPLRGWLRALRGPREPSSAHTLGAPLGASPSPPAG--------RSWVGDPGA 332
             S   S   L G   +     E    +  G   GA+ SPP           +W   P  
Sbjct: 579 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 638

Query: 333 PLTPR---KASCSW-PAPGEASSPGL---------RAGVSAFSCLEEFPGEECSCLAVVV 379
           PL  R    A   W PA G  S+ GL          +   A   L+  P    S      
Sbjct: 639 PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAA 698

Query: 380 ASGKGSPSAS-RGSNWGE--------SFSWHCCTAT---AAALLLQRGDSSASGGAAGPP 427
            +G G+ S S + +  GE        S   H  + T   AAA     G     GGA G  
Sbjct: 699 GAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGG 758

Query: 428 LSGSSPSASRGFSRGEPSSLVS 449
           ++G + +A      G  + L+S
Sbjct: 759 VTGGARAALSDAELGRWAELLS 780


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 50/179 (27%), Positives = 70/179 (39%), Gaps = 35/179 (19%)

Query: 278 PSAGGSPGKSDAPLRGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPR 337
           P  GG+  +S APL  +  A  GP+   +A        A PS P G    G  G  L P 
Sbjct: 279 PPVGGAVAQSSAPLPPFPGAATGPQPMMAA--------AQPSQPQG---AGPGGQTLPPT 327

Query: 338 KASCSWPAPGEASSPGLRAGVSAFSCLEEF----------------PGEECSCLAVVVAS 381
             + + PA      PG   G  A    ++F                P  +   L   VA 
Sbjct: 328 NVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVA- 386

Query: 382 GKGSPSASRGSNWGESFSWHCCTATAAALLLQRGDSSASGGAAGPPLSGSSPSASRGFS 440
           G   PS ++ S+ G + S     ATAA L +  G +++S GA    L G+S   S   +
Sbjct: 387 GLQPPSPAQPSSTGAAAS----PATAATLPVGTGQNASSVGA---QLMGASSQPSEAMA 438


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 43/152 (28%), Positives = 54/152 (35%), Gaps = 39/152 (25%)

Query: 204  VPGSALRELGVRAGGVGGFLRPPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLS 263
            +PG    E+  RA G    + P PPP PTA  P+                          
Sbjct: 1252 LPGPGSPEVK-RAHGTPPPVSPKPPPPPTAPKPV-------------------------- 1284

Query: 264  LTQSACAELAVCAAPSAGGSPGKSDAPLRGWLRALRGPREPSSAHTLGAPLGASPSP--P 321
                     AV   PS    P  + +P R    AL  P  P +  +LGA     PSP  P
Sbjct: 1285 --------KAVAGLPSGSAGPSPAPSPARQPPAALAKP--PGTPPSLGASPAKPPSPGAP 1334

Query: 322  AGRSWVGDPGAPLTPRKASCSWPAPGEASSPG 353
            A       P A      A+ + PAP E +SPG
Sbjct: 1335 ALHVPAKPPRAAAAAAAAAAAPPAPPEGASPG 1366



 Score = 33.1 bits (74), Expect = 0.91
 Identities = 60/242 (24%), Positives = 79/242 (32%), Gaps = 48/242 (19%)

Query: 223  LRPPPPPRPTAAGPLLHVVPVTAIFRSGSNHDRLVHLCPLS----LTQSACAELAVCAAP 278
            L PPPPP       L H+ P+           R     P+S    LTQ           P
Sbjct: 1191 LPPPPPPAEPPPTDLAHLPPLP----PPEGEARKPAKPPVSPKPVLTQ---------PVP 1237

Query: 279  SAGGSPGKSDAPLRGWLRALRGPREPSSAHTLGAPLGASPSPPAGRSWVGDPGAPLTPRK 338
               GSP  +   +      L GP  P      G P   SP PP        P AP  P K
Sbjct: 1238 KLQGSPTPTSKKV-----PLPGPGSPEVKRAHGTPPPVSPKPPP------PPTAP-KPVK 1285

Query: 339  ASCSWPAPGEASSPGLRAGVSAFSCLEEFPGEECSCLAVVVASGKGSPSASRGSNWGESF 398
            A    P+     SP         + L + PG   S    + AS    PS           
Sbjct: 1286 AVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPS----LGASPAKPPSPG--------- 1332

Query: 399  SWHCCTATAAALLLQRGDSSASGGAAGPPL--SGSSPSASRGFSRGEPSSLVSVCFRGKE 456
                  A        R  ++A+  AA PP    G+SP  S      E S+ ++   +  E
Sbjct: 1333 ----APALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSACLAAALQAVE 1388

Query: 457  DE 458
            ++
Sbjct: 1389 EK 1390


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,318,911
Number of Sequences: 37866
Number of extensions: 2256958
Number of successful extensions: 15601
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 533
Number of HSP's that attempted gapping in prelim test: 13422
Number of HSP's gapped (non-prelim): 2771
length of query: 709
length of database: 18,247,518
effective HSP length: 109
effective length of query: 600
effective length of database: 14,120,124
effective search space: 8472074400
effective search space used: 8472074400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.