Search of human proteins with 239747812

Search of human proteins with 239747812

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
         (753 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]      1517   0.0  
gi|239753271 PREDICTED: similar to ankyrin repeat domain 36 [Hom...   381   e-105
gi|169164590 PREDICTED: similar to UNCoordinated family member (...   285   1e-76
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]      240   3e-63
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]      239   7e-63
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]      239   9e-63
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]      236   6e-62
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]      236   6e-62
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]       235   1e-61
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]       235   1e-61
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]      234   3e-61
gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo...   229   9e-60
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]       229   9e-60
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo...   229   9e-60
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo...   228   2e-59
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po...   226   8e-59
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap...   222   1e-57
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap...   222   1e-57
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa...   222   1e-57
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa...   221   1e-57
gi|52856430 protein expressed in prostate, ovary, testis, and pl...   221   2e-57
gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo ...   221   2e-57
gi|153792284 pote protein [Homo sapiens]                              219   6e-57
gi|239747116 PREDICTED: hypothetical protein XP_002343915 isofor...   219   7e-57
gi|239747114 PREDICTED: hypothetical protein XP_002343914 isofor...   219   7e-57
gi|209977003 ANKRD26-like family C, member 3 [Homo sapiens]           218   1e-56
gi|212549546 ANKRD26-like family B, member 2 [Homo sapiens]           218   1e-56
gi|52856434 POTE ankyrin domain family, member G [Homo sapiens]       218   2e-56
gi|153791352 prostate, ovary, testis expressed protein on chromo...   217   3e-56
gi|224282147 prostate-specific P704P [Homo sapiens]                   216   6e-56

>gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 753

 Score = 1517 bits (3928), Expect = 0.0
 Identities = 753/753 (100%), Positives = 753/753 (100%)

Query: 1   MQAAALGTPIAPPHTCPSQDSGDRVVKSGCGPSGATRPKTGAQPHPRGCRVPSVRSCALG 60
           MQAAALGTPIAPPHTCPSQDSGDRVVKSGCGPSGATRPKTGAQPHPRGCRVPSVRSCALG
Sbjct: 1   MQAAALGTPIAPPHTCPSQDSGDRVVKSGCGPSGATRPKTGAQPHPRGCRVPSVRSCALG 60

Query: 61  AGQEQLARAAQPVGPLGAAGRSSGKPRQPTGAAAAAATSTWSRGPRGLGIPDQACASSRA 120
           AGQEQLARAAQPVGPLGAAGRSSGKPRQPTGAAAAAATSTWSRGPRGLGIPDQACASSRA
Sbjct: 61  AGQEQLARAAQPVGPLGAAGRSSGKPRQPTGAAAAAATSTWSRGPRGLGIPDQACASSRA 120

Query: 121 DPGASLAAASQAVCGRSAGHGLPPGVQEARTLRPDGGALRAQEAIPREPRQPPPEPELQC 180
           DPGASLAAASQAVCGRSAGHGLPPGVQEARTLRPDGGALRAQEAIPREPRQPPPEPELQC
Sbjct: 121 DPGASLAAASQAVCGRSAGHGLPPGVQEARTLRPDGGALRAQEAIPREPRQPPPEPELQC 180

Query: 181 RLQVVRWLQLWQPRIPSSRLAPISADPGGDAVAKWGCGPSGGTRRRSTTQPHPWAAEGPA 240
           RLQVVRWLQLWQPRIPSSRLAPISADPGGDAVAKWGCGPSGGTRRRSTTQPHPWAAEGPA
Sbjct: 181 RLQVVRWLQLWQPRIPSSRLAPISADPGGDAVAKWGCGPSGGTRRRSTTQPHPWAAEGPA 240

Query: 241 RGTPSVGSLWKRRARGRQLNRPWGRARLALQGAPPSRGTSAATAACTGRARAARAVSLPR 300
           RGTPSVGSLWKRRARGRQLNRPWGRARLALQGAPPSRGTSAATAACTGRARAARAVSLPR
Sbjct: 241 RGTPSVGSLWKRRARGRQLNRPWGRARLALQGAPPSRGTSAATAACTGRARAARAVSLPR 300

Query: 301 ACWAGPAKVRVLAGYNLQPTIKEDDERERWPTLMERLCSDGFAFPHYYIKPYHLKRIHRA 360
           ACWAGPAKVRVLAGYNLQPTIKEDDERERWPTLMERLCSDGFAFPHYYIKPYHLKRIHRA
Sbjct: 301 ACWAGPAKVRVLAGYNLQPTIKEDDERERWPTLMERLCSDGFAFPHYYIKPYHLKRIHRA 360

Query: 361 VLHGNLEKLKYLLLTYYDANKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCDREDR 420
           VLHGNLEKLKYLLLTYYDANKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCDREDR
Sbjct: 361 VLHGNLEKLKYLLLTYYDANKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCDREDR 420

Query: 421 TPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLSHGTNIEE 480
           TPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLSHGTNIEE
Sbjct: 421 TPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLSHGTNIEE 480

Query: 481 CSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQH 540
           CSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQH
Sbjct: 481 CSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQH 540

Query: 541 NIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYEDLPINSNPVSSQKQPALKATS 600
           NIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYEDLPINSNPVSSQKQPALKATS
Sbjct: 541 NIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYEDLPINSNPVSSQKQPALKATS 600

Query: 601 GKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAV 660
           GKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAV
Sbjct: 601 GKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAV 660

Query: 661 EQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRC 720
           EQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRC
Sbjct: 661 EQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRC 720

Query: 721 LYLLDRFAQPVTKDKFALESEVEYSLVKLIFSF 753
           LYLLDRFAQPVTKDKFALESEVEYSLVKLIFSF
Sbjct: 721 LYLLDRFAQPVTKDKFALESEVEYSLVKLIFSF 753


>gi|239753271 PREDICTED: similar to ankyrin repeat domain 36 [Homo
           sapiens]
          Length = 501

 Score =  381 bits (978), Expect = e-105
 Identities = 186/195 (95%), Positives = 188/195 (96%)

Query: 19  QDSGDRVVKSGCGPSGATRPKTGAQPHPRGCRVPSVRSCALGAGQEQLARAAQPVGPLGA 78
           +D GD VVKSGCGPSGATRPKTGAQPHP GC VPS RSCALG GQEQLARAAQP+GPLGA
Sbjct: 209 RDLGDGVVKSGCGPSGATRPKTGAQPHPGGCGVPSARSCALGVGQEQLARAAQPMGPLGA 268

Query: 79  AGRSSGKPRQPTGAAAAAATSTWSRGPRGLGIPDQACASSRADPGASLAAASQAVCGRSA 138
           AGRSSGKPRQPTGAAAAAATSTWSRGPRGLGIPDQACASSRADPGASLAAASQAVCGRSA
Sbjct: 269 AGRSSGKPRQPTGAAAAAATSTWSRGPRGLGIPDQACASSRADPGASLAAASQAVCGRSA 328

Query: 139 GHGLPPGVQEARTLRPDGGALRAQEAIPREPRQPPPEPELQCRLQVVRWLQLWQPRIPSS 198
           GHGL PGVQEARTLRPDGGALRAQEAIPREPRQPPPEPELQCRLQVVRWLQLWQPRIPSS
Sbjct: 329 GHGLRPGVQEARTLRPDGGALRAQEAIPREPRQPPPEPELQCRLQVVRWLQLWQPRIPSS 388

Query: 199 RLAPISADPGGDAVA 213
           RLAPISADPGGDAVA
Sbjct: 389 RLAPISADPGGDAVA 403



 Score =  224 bits (572), Expect = 2e-58
 Identities = 147/301 (48%), Positives = 171/301 (56%), Gaps = 38/301 (12%)

Query: 209 GDAVAKWGCGPSGGTRRRSTTQPHPWAAEGPARGTPSVGSLWKRRARGRQLNRPWGRARL 268
           GD V K GCGPSG TR ++  QPHP     P+  + ++G   ++ AR  Q   P G A  
Sbjct: 212 GDGVVKSGCGPSGATRPKTGAQPHPGGCGVPSARSCALGVGQEQLARAAQPMGPLGAA-- 269

Query: 269 ALQGAPPSRGTSAATAACTGR-ARAARAVSLP-RACW------------AGPAKVRVLAG 314
                 P + T AA AA T   +R  R + +P +AC             A  A     AG
Sbjct: 270 GRSSGKPRQPTGAAAAAATSTWSRGPRGLGIPDQACASSRADPGASLAAASQAVCGRSAG 329

Query: 315 YNLQPTIKEDDERERWPTLMERLCSDGFAFPHYYIKPYHLKRIH-RAVLHGNLEKLKYLL 373
           + L+P ++E             L  DG A       P   ++      L   L+ +++L 
Sbjct: 330 HGLRPGVQE----------ARTLRPDGGALRAQEAIPREPRQPPPEPELQCRLQVVRWLQ 379

Query: 374 LTYYDANKR-----------DRKERTALHLACATGQPEMVHLLVSRRCELNLCDREDRTP 422
           L                   D    TALHLACATGQPEMVHLLVSRRCELNLCDREDRTP
Sbjct: 380 LWQPRIPSSRLAPISADPGGDAVAMTALHLACATGQPEMVHLLVSRRCELNLCDREDRTP 439

Query: 423 LIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLSHGTNIEECS 482
           LIKAVQLRQEACATLLLQNGA+PNITD FGRTALHYAVYNEDTSMIEKLLSHGTNIEECS
Sbjct: 440 LIKAVQLRQEACATLLLQNGADPNITDVFGRTALHYAVYNEDTSMIEKLLSHGTNIEECS 499

Query: 483 K 483
           K
Sbjct: 500 K 500



 Score = 37.0 bits (84), Expect = 0.068
 Identities = 23/71 (32%), Positives = 36/71 (50%)

Query: 489 LLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNIDVLSRD 548
           L  A +  + +MV  L+ ++  +N  D   R+ LI AV L ++    LLLQ+  D    D
Sbjct: 407 LHLACATGQPEMVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGADPNITD 466

Query: 549 AFRKIAGDYAI 559
            F + A  YA+
Sbjct: 467 VFGRTALHYAV 477


>gi|169164590 PREDICTED: similar to UNCoordinated family member
           (unc-44) [Homo sapiens]
          Length = 163

 Score =  285 bits (728), Expect = 1e-76
 Identities = 137/161 (85%), Positives = 148/161 (91%)

Query: 323 EDDERERWPTLMERLCSDGFAFPHYYIKPYHLKRIHRAVLHGNLEKLKYLLLTYYDANKR 382
           +D E +RWPTL +RLCSDGF FP Y IKPYHLK IHRAV + +LE+LK++LLT YD NKR
Sbjct: 2   DDKEPKRWPTLRDRLCSDGFLFPQYPIKPYHLKGIHRAVFYRDLEELKFVLLTRYDINKR 61

Query: 383 DRKERTALHLACATGQPEMVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNG 442
           DRKERTALHLACATGQPEMVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNG
Sbjct: 62  DRKERTALHLACATGQPEMVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNG 121

Query: 443 ANPNITDFFGRTALHYAVYNEDTSMIEKLLSHGTNIEECSK 483
           A+PNITD FGRTALHYAVYNEDTSMIEKLLS+G NIEECS+
Sbjct: 122 ADPNITDVFGRTALHYAVYNEDTSMIEKLLSYGANIEECSE 162



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 31/118 (26%), Positives = 57/118 (48%)

Query: 456 LHYAVYNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAID 515
           +H AV+  D   ++ +L    +I +  + E   L  A +  + +MV  L+ ++  +N  D
Sbjct: 36  IHRAVFYRDLEELKFVLLTRYDINKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCD 95

Query: 516 YLGRSALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEY 573
              R+ LI AV L ++    LLLQ+  D    D F + A  YA+  ++  + + +  Y
Sbjct: 96  REDRTPLIKAVQLRQEACATLLLQNGADPNITDVFGRTALHYAVYNEDTSMIEKLLSY 153


>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1139

 Score =  240 bits (613), Expect = 3e-63
 Identities = 177/493 (35%), Positives = 249/493 (50%), Gaps = 39/493 (7%)

Query: 196 PSSRLAPISADPGGDAVAKWGCGPSGGTRRRSTTQPHPWAAEGPARGTPSVGSLWK---- 251
           PS  + P +A PG                +  T  P P  A+GP  G P + S  +    
Sbjct: 7   PSQAVCPAAAAPG----------------QEPTLSPIP--ADGPWSG-PDLSSEKRGGSH 47

Query: 252 ----RRARGRQLNRPWGRARLALQGAP------PSRGTSAATAACTGRARAARA----VS 297
               R AR R  N P    R     AP      PS G +++ A    RA A       VS
Sbjct: 48  GQAGRDARLRFRNVPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRAGAELGRRLRVS 107

Query: 298 LPRACWAGPAKVRVLAGYNLQPTIKEDDERERWPTLMERLCSDGFAFPHYYIKPYHLKRI 357
           L +A     A  R+L+   +    K      R    +       +A   Y+I+ + L++I
Sbjct: 108 LLKAV-VDRAGSRILSYIAVATMRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKI 166

Query: 358 HRAVLHGNLEKLKYLLLTYY-DANKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCD 416
           HRA + G+  ++++ L   + D + RDRK+RT LHLACA G+ ++V LL+ R+C++N+CD
Sbjct: 167 HRAAIKGDAAEVEHCLTRRFRDLDVRDRKDRTVLHLACAHGRVQVVTLLLDRKCQINICD 226

Query: 417 REDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLSHGT 476
           R +RTPL+KAV  ++EACA +LL+ GANPNI D +G TALHYAVYNE TS+ E+LLSH  
Sbjct: 227 RLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHA 286

Query: 477 NIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVIL 536
           NIE  +K    PLLFA++ R+  MVEFLLK +AN++A+D   R+ALI AV      IV L
Sbjct: 287 NIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTL 346

Query: 537 LLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYEDLPINSNPVSSQKQPAL 596
           LLQ NI + S+D F + A DYA     R I   I E+K K  ++   N N  ++  +P  
Sbjct: 347 LLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPEN 406

Query: 597 KATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTV 656
                K   +       K        S +KQ  L+ + +K    S +  + KDE     +
Sbjct: 407 LKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFM 466

Query: 657 LPAVEQCLNRSLY 669
           L      L   LY
Sbjct: 467 LKRDIAMLKEELY 479


>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1366

 Score =  239 bits (610), Expect = 7e-63
 Identities = 176/493 (35%), Positives = 249/493 (50%), Gaps = 39/493 (7%)

Query: 196 PSSRLAPISADPGGDAVAKWGCGPSGGTRRRSTTQPHPWAAEGPARGTPSVGSLWK---- 251
           PS  + P +A PG                +  T  P P  A+GP  G P + S  +    
Sbjct: 7   PSQAVCPAAAAPG----------------QEPTLSPIP--ADGPWSG-PDLSSEKRGGSH 47

Query: 252 ----RRARGRQLNRPWGRARLALQGAP------PSRGTSAATAACTGRARAARA----VS 297
               R AR R  N P    R     AP      PS G +++ A    RA A       VS
Sbjct: 48  GQAGRDARLRFRNVPRQPRRTRKPAAPEPELQSPSAGHASSRAPSGVRAGAELGRRLRVS 107

Query: 298 LPRACWAGPAKVRVLAGYNLQPTIKEDDERERWPTLMERLCSDGFAFPHYYIKPYHLKRI 357
           L +A     A  R+L+   +    K      R    +       +A   Y+I+ + L++I
Sbjct: 108 LLKAV-VDRAGSRILSYIAVATMRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKI 166

Query: 358 HRAVLHGNLEKLKYLLLTYY-DANKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCD 416
           HRA + G+  ++++ L   + D + RD+K+RT LHLACA G+ ++V LL+ R+C++N+CD
Sbjct: 167 HRAAIKGDAAEVEHCLTRRFRDLDVRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICD 226

Query: 417 REDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLSHGT 476
           R +RTPL+KAV  ++EACA +LL+ GANPNI D +G TALHYAVYNE TS+ E+LLSH  
Sbjct: 227 RLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHA 286

Query: 477 NIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVIL 536
           NIE  +K    PLLFA++ R+  MVEFLLK +AN++A+D   R+ALI AV      IV L
Sbjct: 287 NIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTL 346

Query: 537 LLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYEDLPINSNPVSSQKQPAL 596
           LLQ NI + S+D F + A DYA     R I   I E+K K  ++   N N  ++  +P  
Sbjct: 347 LLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPEN 406

Query: 597 KATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTV 656
                K   +       K        S +KQ  L+ + +K    S +  + KDE     +
Sbjct: 407 LKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFM 466

Query: 657 LPAVEQCLNRSLY 669
           L      L   LY
Sbjct: 467 LKRDIAMLKEELY 479


>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1363

 Score =  239 bits (609), Expect = 9e-63
 Identities = 167/477 (35%), Positives = 242/477 (50%), Gaps = 36/477 (7%)

Query: 196 PSSRLAPISADPGGDAVAKWGCGPSGGTRRRSTTQPHPWAAEGPARGTPSVGSLWKRRAR 255
           PS  + P +A PG                +  T  P P  A+GP  G P + S      R
Sbjct: 7   PSQAVCPAAAAPG----------------QEPTLSPIP--ADGPWSG-PDLSS----EKR 43

Query: 256 GRQLNRPWGRARLALQGAPPSRGTSAATAACTGRARAARAVSLPRACWAGPAKVRVLAGY 315
           G    +    ARL     P     +   AA     ++  A         G A  R  +G 
Sbjct: 44  GGSHGQAGRDARLRFWNVPRQPRRTRKPAAPEPELQSPSA---------GHASSRAPSGV 94

Query: 316 NLQPTIKE--DDERERWPTLMERLCSDGFAFPHYYIKPYHLKRIHRAVLHGNLEKLKYLL 373
               T+++     R     L+  +  + +A   Y+I+ + L++IHRA + G+  ++++ L
Sbjct: 95  RAVATMRKLLSFGRRLGQALLSSMDQE-YAGRGYHIRDWELRKIHRAAIKGDAAEVEHCL 153

Query: 374 LTYY-DANKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCDREDRTPLIKAVQLRQE 432
              + D + RD+K+RT LHLACA G+ ++V LL+ R+C++N+CDR +RTPL+KAV  ++E
Sbjct: 154 TRRFRDLDVRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEE 213

Query: 433 ACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLSHGTNIEECSKCEYQPLLFA 492
           ACA +LL+ GANPNI D +G TALHYAVYNE TS+ E+LLSH  NIE  +K    PLLFA
Sbjct: 214 ACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFA 273

Query: 493 VSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNIDVLSRDAFRK 552
           ++ R+  MVEFLLK +AN++A+D   R+ALI AV      IV LLLQ NI + S+D F +
Sbjct: 274 INSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQ 333

Query: 553 IAGDYAIEAKNRVIFDLIYEYKRKRYEDLPINSNPVSSQKQPALKATSGKEDSISNIATE 612
            A DYA     R I   I E+K K  ++   N N  ++  +P       K   +      
Sbjct: 334 TAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEG 393

Query: 613 IKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLY 669
            K        S +KQ  L+ + +K    S +  + KDE     +L      L   LY
Sbjct: 394 AKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELY 450


>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
          Length = 1415

 Score =  236 bits (602), Expect = 6e-62
 Identities = 166/440 (37%), Positives = 235/440 (53%), Gaps = 35/440 (7%)

Query: 196 PSSRLAPISADPGGDAVAKWGCGPSGGTRRRSTTQPHP-WAAEGPARGTPSVGSLWKRRA 254
           PS  + P +A PG                +  T Q HP W    P  G P + S  +R  
Sbjct: 7   PSQAVYPAAAAPG----------------QEPTPQSHPRWLRRAPVSG-PDLSSEEERVG 49

Query: 255 RGRQLNRPWGR-ARLALQGAP--PSRGTSAATAACTGRARAARAVSLPRACWA-GPAKVR 310
              Q     GR A L  +  P  P R    AT A   +   A    L  A      A +R
Sbjct: 50  SQGQAGPQAGRDALLGFRDVPREPRRTRKPATRAPVLQVPPAGHEGLGAASGVPAVATMR 109

Query: 311 VLAGYNLQPTIKEDDERERWPTLMERLCSDGFAFPHYYIKPYHLKRIHRAVLHGNLEKLK 370
            L  +           R     L+  +  + +A P Y I+ + L++IHRA + G+  +++
Sbjct: 110 KLFSFG----------RRLGQALLSSMDQE-YAGPGYDIRDWELRKIHRAAIKGDAAEVE 158

Query: 371 YLLLTYY-DANKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCDREDRTPLIKAVQL 429
             L   + D + RDRK+RT LHLACA G+ ++V LL+ RRC++++CDR +RTPL+KAV  
Sbjct: 159 RCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHS 218

Query: 430 RQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLSHGTNIEECSKCEYQPL 489
           ++EACA +LL+ GANPNI D +G TALHYAVYN+ TS+ E+LLSH  NIE  +K    PL
Sbjct: 219 QEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPL 278

Query: 490 LFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNIDVLSRDA 549
           LFA++ R+  MVEFLLK +AN++A+D   R+ALI AV      IV LLLQ NI + S+D 
Sbjct: 279 LFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDM 338

Query: 550 FRKIAGDYAIEAKNRVIFDLIYEYKRKRYEDLPINSNPVSSQKQPA-LKATSGKEDSISN 608
           F + A DYA+ +  R I   I E+K K  ++   N N  ++  +PA LK    +  +  N
Sbjct: 339 FGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHN 398

Query: 609 IATEIKDGQKSGTVSSQKQP 628
           +    ++ Q+    S  KQP
Sbjct: 399 LKVASEEKQERLQRSENKQP 418


>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
          Length = 1415

 Score =  236 bits (602), Expect = 6e-62
 Identities = 166/440 (37%), Positives = 235/440 (53%), Gaps = 35/440 (7%)

Query: 196 PSSRLAPISADPGGDAVAKWGCGPSGGTRRRSTTQPHP-WAAEGPARGTPSVGSLWKRRA 254
           PS  + P +A PG                +  T Q HP W    P  G P + S  +R  
Sbjct: 7   PSQAVYPAAAAPG----------------QEPTPQSHPRWLRRAPVSG-PDLSSEEERVG 49

Query: 255 RGRQLNRPWGR-ARLALQGAP--PSRGTSAATAACTGRARAARAVSLPRACWA-GPAKVR 310
              Q     GR A L  +  P  P R    AT A   +   A    L  A      A +R
Sbjct: 50  SQGQAGPQAGRDALLGFRDVPREPRRTRKPATRAPVLQVPPAGHEGLGAASGVPAVATMR 109

Query: 311 VLAGYNLQPTIKEDDERERWPTLMERLCSDGFAFPHYYIKPYHLKRIHRAVLHGNLEKLK 370
            L  +           R     L+  +  + +A P Y I+ + L++IHRA + G+  +++
Sbjct: 110 KLFSFG----------RRLGQALLSSMDQE-YAGPGYDIRDWELRKIHRAAIKGDAAEVE 158

Query: 371 YLLLTYY-DANKRDRKERTALHLACATGQPEMVHLLVSRRCELNLCDREDRTPLIKAVQL 429
             L   + D + RDRK+RT LHLACA G+ ++V LL+ RRC++++CDR +RTPL+KAV  
Sbjct: 159 RCLTRRFRDLDARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHS 218

Query: 430 RQEACATLLLQNGANPNITDFFGRTALHYAVYNEDTSMIEKLLSHGTNIEECSKCEYQPL 489
           ++EACA +LL+ GANPNI D +G TALHYAVYN+ TS+ E+LLSH  NIE  +K    PL
Sbjct: 219 QEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPL 278

Query: 490 LFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNIDVLSRDA 549
           LFA++ R+  MVEFLLK +AN++A+D   R+ALI AV      IV LLLQ NI + S+D 
Sbjct: 279 LFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDM 338

Query: 550 FRKIAGDYAIEAKNRVIFDLIYEYKRKRYEDLPINSNPVSSQKQPA-LKATSGKEDSISN 608
           F + A DYA+ +  R I   I E+K K  ++   N N  ++  +PA LK    +  +  N
Sbjct: 339 FGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHN 398

Query: 609 IATEIKDGQKSGTVSSQKQP 628
           +    ++ Q+    S  KQP
Sbjct: 399 LKVASEEKQERLQRSENKQP 418


>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 948

 Score =  235 bits (600), Expect = 1e-61
 Identities = 120/120 (100%), Positives = 120/120 (100%)

Query: 622 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 681
           VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN
Sbjct: 20  VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79

Query: 682 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 741
           EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE
Sbjct: 80  EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 139



 Score =  116 bits (290), Expect = 9e-26
 Identities = 66/115 (57%), Positives = 78/115 (67%)

Query: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
           VSSQKQPALKAT+ +EDS+SNIATEIKDG+KSGTVSSQKQPALK T+D+ DSVSN ATEI
Sbjct: 400 VSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEI 459

Query: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
           KD +KSGTV       L  +     +V     EN+   +S  +S    P  K  S
Sbjct: 460 KDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATS 514



 Score =  108 bits (271), Expect = 1e-23
 Identities = 62/107 (57%), Positives = 74/107 (69%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQKQPA KATS K DS  NIATEIKDG + GTVSSQKQPALK T+D++DSVSN A
Sbjct: 363 SGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIA 422

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIIS 691
           TEIKD +KSGTV    +  L  +    D+V+   TE +   +S  +S
Sbjct: 423 TEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVS 469



 Score =  103 bits (256), Expect = 8e-22
 Identities = 56/74 (75%), Positives = 59/74 (79%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQKQPALKA   KEDS+ N+ATE KD Q SGTVSSQKQPALK TSDK DSVSN  
Sbjct: 805 SRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIP 864

Query: 645 TEIKDEQKSGTVLP 658
           TEIKD Q+SGTV P
Sbjct: 865 TEIKDGQQSGTVSP 878



 Score =  100 bits (249), Expect = 5e-21
 Identities = 80/224 (35%), Positives = 116/224 (51%), Gaps = 8/224 (3%)

Query: 485 EYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNID- 543
           E  P L A S  K  ++     KK          +       T  E+D V+ + + N D 
Sbjct: 675 EKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDG 734

Query: 544 VLSRD-AFRKIAGDYAIEAKNRVIFDLIYEYKRKRYEDLPINSNPVSSQKQPALKATSGK 602
             SR  +  K +G  A  A+   + ++    + K+Y +    +  VSS+K+PALKATS +
Sbjct: 735 EKSRTVSSEKPSGLKATSAEKDSVLNIA---RGKKYGE---KTKRVSSRKKPALKATSDE 788

Query: 603 EDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ 662
           +DS+  IA E KDG+KS TVSSQKQPALK   DK+DSV N ATE KDEQ SGTV    + 
Sbjct: 789 KDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQP 848

Query: 663 CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSI 706
            L  +  + D+V+   TE +   +S  +S      +K+I  + +
Sbjct: 849 ALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKV 892



 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 54/71 (76%), Positives = 59/71 (83%)

Query: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
           VSSQKQPA KATS  +DS+SNIATEIK+G  SGTVSSQKQPA K TSD+ DSVSN ATEI
Sbjct: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323

Query: 648 KDEQKSGTVLP 658
           K  Q+SGTV P
Sbjct: 324 KKGQQSGTVSP 334



 Score = 94.4 bits (233), Expect = 4e-19
 Identities = 50/72 (69%), Positives = 59/72 (81%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQKQPALKAT+ ++DS+SNIATEIKDG+KSGTVSSQK PAL  TSD++ SV + A
Sbjct: 431 SGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIA 490

Query: 645 TEIKDEQKSGTV 656
            E KD +KS TV
Sbjct: 491 RENKDGEKSRTV 502



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 63/149 (42%), Positives = 74/149 (49%), Gaps = 34/149 (22%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQ--------------------------- 617
           S  VSSQKQPA KATS ++DS+SNIATEIK GQ                           
Sbjct: 295 SGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIA 354

Query: 618 -------KSGTVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYR 670
                  KSGTVSSQKQPA K TSDK DS  N ATEIKD  + GTV    +  L  +   
Sbjct: 355 TRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDE 414

Query: 671 PDAVAQPVTENEFSLESEIISKLYIPKRK 699
            D+V+   TE +   +S  +S    P  K
Sbjct: 415 EDSVSNIATEIKDGEKSGTVSSQKQPALK 443



 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 54/93 (58%), Positives = 63/93 (67%), Gaps = 3/93 (3%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQKQPALKATS K+DS+SNI TEIKDGQ+SGTVS QKQ A K    K  S+ N A
Sbjct: 839 SGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVSLLNIA 898

Query: 645 TEIKDEQKSGTVL-PAVE--QCLNRSLYRPDAV 674
           T I    KSGTV+  A+E  +CL  +  +P  V
Sbjct: 899 TRITGGWKSGTVIRQAIEHDECLCYTGIKPSDV 931



 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 51/107 (47%), Positives = 63/107 (58%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQK PALK TS +EDS+  IA E KDG+KS TVSS+K P LK TSD+ DSV N A
Sbjct: 635 SRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIA 694

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIIS 691
              KD +K+ TV       L  +    D+V     EN+   +S  +S
Sbjct: 695 RGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVS 741



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 58/139 (41%), Positives = 76/139 (54%), Gaps = 12/139 (8%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSS+K P LKATS ++DS+ NIA   KDG+K+ TVSSQK P LK TSD++DSV + A
Sbjct: 669 SRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDEEDSVLSIA 728

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPR 704
            E KD +KS TV          S  +P  +     E + S+ +    K Y  K K +S R
Sbjct: 729 RENKDGEKSRTV----------SSEKPSGLKATSAEKD-SVLNIARGKKYGEKTKRVSSR 777

Query: 705 SIKDVLPPVEEAVDRCLYL 723
             K  L    +  D  LY+
Sbjct: 778 K-KPALKATSDEKDSVLYI 795



 Score = 77.4 bits (189), Expect = 5e-14
 Identities = 42/69 (60%), Positives = 52/69 (75%)

Query: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
           VSS+K+P+L+ATS ++DS SNI  E KDG+ S  VSSQK PALK TSD++DSV   A E 
Sbjct: 604 VSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIAREN 663

Query: 648 KDEQKSGTV 656
           KD +KS TV
Sbjct: 664 KDGEKSRTV 672



 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 49/118 (41%), Positives = 65/118 (55%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSS+K+PA KATS ++DS SNI    KDG+ S  VSSQK P LK TSD++DSV   A
Sbjct: 499 SRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIA 558

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
            E KD +KS TV       L  S    D+V       ++  +++ +S    P  +  S
Sbjct: 559 RENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATS 616



 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 51/118 (43%), Positives = 64/118 (54%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQK PAL ATS +E S+ +IA E KDG+KS TVSS+K+PA K TSD+ DS SN  
Sbjct: 465 SGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNIT 524

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
              KD + S  V       L  +    D+V     EN+   +S  +S    P  K  S
Sbjct: 525 RGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASS 582



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 47/115 (40%), Positives = 61/115 (53%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQK P LK TS +EDS+  IA E KDG+KS TVSS+K P LK +SD+ DSV N A
Sbjct: 533 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIA 592

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
              K  +K+  V    +  L  +    D+ +    E +    S  +S    P  K
Sbjct: 593 RGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALK 647



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 46/118 (38%), Positives = 64/118 (54%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSS+K P LKA+S ++DS+ NIA   K G+K+  VSS+K+P+L+ TSD+ DS SN  
Sbjct: 567 SRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNIT 626

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
            E KD + S  V       L  +    D+V     EN+   +S  +S    P  K  S
Sbjct: 627 REKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATS 684



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 46/124 (37%), Positives = 62/124 (50%)

Query: 583 INSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSN 642
           + S+  SS++ P    T  + D  S  A   KD    G VSSQKQPA K TSD  DSVSN
Sbjct: 225 LTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSN 284

Query: 643 TATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
            ATEIK+   SGTV    +     +    D+V+   TE +   +S  +S      RK+I 
Sbjct: 285 IATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIF 344

Query: 703 PRSI 706
            + +
Sbjct: 345 KKKV 348


>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 1524

 Score =  235 bits (600), Expect = 1e-61
 Identities = 120/120 (100%), Positives = 120/120 (100%)

Query: 622 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 681
           VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN
Sbjct: 20  VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79

Query: 682 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 741
           EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE
Sbjct: 80  EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 139



 Score =  115 bits (289), Expect = 1e-25
 Identities = 66/115 (57%), Positives = 78/115 (67%)

Query: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
           VSSQKQPALKAT+ +EDS+SNIATEIKDG+KSGTVSSQKQPALK T+D+ DSVSN ATEI
Sbjct: 400 VSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEI 459

Query: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
           KD +KSGTV       L  +     +V     EN+   +S  +S    P  K  S
Sbjct: 460 KDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATS 514



 Score =  108 bits (271), Expect = 1e-23
 Identities = 62/107 (57%), Positives = 74/107 (69%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQKQPA KATS K DS  NIATEIKDG + GTVSSQKQPALK T+D++DSVSN A
Sbjct: 363 SGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIA 422

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIIS 691
           TEIKD +KSGTV    +  L  +    D+V+   TE +   +S  +S
Sbjct: 423 TEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVS 469



 Score =  101 bits (252), Expect = 2e-21
 Identities = 55/71 (77%), Positives = 58/71 (81%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VS QKQPALKATS K+DS+SNI TEIKDGQ+SGTVSSQKQPA K TS K DSVSN A
Sbjct: 737 SGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIA 796

Query: 645 TEIKDEQKSGT 655
           TEIKD Q  GT
Sbjct: 797 TEIKDGQIRGT 807



 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 54/71 (76%), Positives = 59/71 (83%)

Query: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
           VSSQKQPA KATS  +DS+SNIATEIK+G  SGTVSSQKQPA K TSD+ DSVSN ATEI
Sbjct: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323

Query: 648 KDEQKSGTVLP 658
           K  Q+SGTV P
Sbjct: 324 KKGQQSGTVSP 334



 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 56/93 (60%), Positives = 64/93 (68%)

Query: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
           VSS KQPALKA   KEDS+ N+ATE KD Q SGTVS QKQPALK TSDK DSVSN  TEI
Sbjct: 706 VSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEI 765

Query: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTE 680
           KD Q+SGTV    +     +  + D+V+   TE
Sbjct: 766 KDGQQSGTVSSQKQPAWKATSVKKDSVSNIATE 798



 Score = 94.4 bits (233), Expect = 4e-19
 Identities = 50/72 (69%), Positives = 59/72 (81%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQKQPALKAT+ ++DS+SNIATEIKDG+KSGTVSSQK PAL  TSD++ SV + A
Sbjct: 431 SGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIA 490

Query: 645 TEIKDEQKSGTV 656
            E KD +KS TV
Sbjct: 491 RENKDGEKSRTV 502



 Score = 94.0 bits (232), Expect = 5e-19
 Identities = 60/143 (41%), Positives = 84/143 (58%), Gaps = 2/143 (1%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSS+K P LKATS ++DS+ NIA   KDG+K+ TVSS KQPALK   DK+DSV N A
Sbjct: 669 SRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMA 728

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPR 704
           TE KDEQ SGTV    +  L  +  + D+V+   TE +   +S  +S    P  K  S +
Sbjct: 729 TEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVK 788

Query: 705 --SIKDVLPPVEEAVDRCLYLLD 725
             S+ ++   +++   R   +L+
Sbjct: 789 KDSVSNIATEIKDGQIRGTGILE 811



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 63/149 (42%), Positives = 74/149 (49%), Gaps = 34/149 (22%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQ--------------------------- 617
           S  VSSQKQPA KATS ++DS+SNIATEIK GQ                           
Sbjct: 295 SGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIA 354

Query: 618 -------KSGTVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYR 670
                  KSGTVSSQKQPA K TSDK DS  N ATEIKD  + GTV    +  L  +   
Sbjct: 355 TRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDE 414

Query: 671 PDAVAQPVTENEFSLESEIISKLYIPKRK 699
            D+V+   TE +   +S  +S    P  K
Sbjct: 415 EDSVSNIATEIKDGEKSGTVSSQKQPALK 443



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 54/120 (45%), Positives = 67/120 (55%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQK PALK TS +EDS+  IA E KDG+KS TVSS+K P LK TSD+ DSV N A
Sbjct: 635 SRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIA 694

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPR 704
              KD +K+ TV    +  L     + D+V    TE +    S  +S    P  K  S +
Sbjct: 695 RGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDK 754



 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 47/90 (52%), Positives = 56/90 (62%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSS+K+PALKATS ++DS SNI    KDG+ S  VSSQK P LK TSD++DSV   A
Sbjct: 499 SRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIA 558

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAV 674
            E KD +KS TV       L  S    D+V
Sbjct: 559 RENKDGEKSRTVSSEKPPGLKASSAEKDSV 588



 Score = 77.4 bits (189), Expect = 5e-14
 Identities = 42/69 (60%), Positives = 52/69 (75%)

Query: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
           VSS+K+P+L+ATS ++DS SNI  E KDG+ S  VSSQK PALK TSD++DSV   A E 
Sbjct: 604 VSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIAREN 663

Query: 648 KDEQKSGTV 656
           KD +KS TV
Sbjct: 664 KDGEKSRTV 672



 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 47/118 (39%), Positives = 65/118 (55%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSS+K P LKA+S ++DS+ NIA   KDG+K+  VSS+K+P+L+ TSD+ DS SN  
Sbjct: 567 SRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNIT 626

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
            E KD + S  V       L  +    D+V     EN+   +S  +S    P  K  S
Sbjct: 627 REKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATS 684



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 47/115 (40%), Positives = 61/115 (53%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQK P LK TS +EDS+  IA E KDG+KS TVSS+K P LK +S + DSV N A
Sbjct: 533 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIA 592

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
              KD +K+  V    +  L  +    D+ +    E +    S  +S    P  K
Sbjct: 593 RGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALK 647



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 50/122 (40%), Positives = 58/122 (47%), Gaps = 26/122 (21%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGT----------------------- 621
           S  VSSQKQPA KATS K+DS+SNIATEIKDGQ  GT                       
Sbjct: 771 SGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNK 830

Query: 622 ---VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPV 678
              VS QKQ A K    K  S+ N AT I    KSGT  P     L  ++   ++V    
Sbjct: 831 SAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTA 890

Query: 679 TE 680
           T+
Sbjct: 891 TK 892



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 45/124 (36%), Positives = 61/124 (49%)

Query: 583 INSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSN 642
           + S+  SS++ P    T  + D  S  A   KD    G VSSQKQPA K TSD  DSVSN
Sbjct: 225 LTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSN 284

Query: 643 TATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
            ATEIK+   SGTV    +     +    D+V+   TE +   +S  +S       K+I 
Sbjct: 285 IATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIF 344

Query: 703 PRSI 706
            + +
Sbjct: 345 KKKV 348



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 58/170 (34%), Positives = 78/170 (45%), Gaps = 12/170 (7%)

Query: 484 CEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNID 543
           C+ QP L A S +K  +     + K    +     +       T  +KD V      NI 
Sbjct: 742 CQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSV-----SNIA 796

Query: 544 VLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYEDLPINSNPVSSQKQPALKATSGKE 603
              +D   +I G   +E    V+FD I E    ++  L   S  VS QKQ A K    K+
Sbjct: 797 TEIKDG--QIRGTGILEYTFNVMFDQIEE----KFTSLN-KSAGVSPQKQSAQKVIFKKK 849

Query: 604 DSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDEQKS 653
            S+ NIAT I  G KSGT   +  P LK T +  +SV NTAT++KD Q S
Sbjct: 850 VSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 899



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 16/57 (28%), Positives = 29/57 (50%)

Query: 594 PALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDE 650
           P LKAT   ++S+ N AT++KD Q S       + A +    + +   N   ++K++
Sbjct: 874 PTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQ 930


>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
          Length = 1002

 Score =  234 bits (596), Expect = 3e-61
 Identities = 131/289 (45%), Positives = 188/289 (65%), Gaps = 2/289 (0%)

Query: 342 FAFPHYYIKPYHLKRIHRAVLHGNLEKLKYLLLTYY-DANKRDRKERTALHLACATGQPE 400
           +A P Y I+ + L++IHRA + G+  +++  L   + D + RDRK+RT LHLACA G+ +
Sbjct: 23  YAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLDARDRKDRTVLHLACAHGRVQ 82

Query: 401 MVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAV 460
           +V LL+ RRC++++CDR +RTPL+KAV  ++EACA +LL+ GANPNI D +G TALHYAV
Sbjct: 83  VVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAV 142

Query: 461 YNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRS 520
           YN+ TS+ E+LLSH  NIE  +K    PLLFA++ R+  MVEFLLK +AN++A+D   R+
Sbjct: 143 YNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRT 202

Query: 521 ALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYED 580
           ALI AV      IV LLLQ NI + S+D F + A DYA+ +  R I   I E+K K  ++
Sbjct: 203 ALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKN 262

Query: 581 LPINSNPVSSQKQPA-LKATSGKEDSISNIATEIKDGQKSGTVSSQKQP 628
              N N  ++  +PA LK    +  +  N+    ++ Q+    S  KQP
Sbjct: 263 HLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQP 311


>gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo
           sapiens]
          Length = 498

 Score =  229 bits (583), Expect = 9e-60
 Identities = 129/297 (43%), Positives = 187/297 (62%), Gaps = 11/297 (3%)

Query: 342 FAFPHYYIKPYHLKRIHRAVLHGNLEKLKYL-LLTYYDANKRDRKERTALHLACATGQPE 400
           F  P Y+++   L ++HRA   G + +   + +L     NKRD+K+RTALHLACA G  E
Sbjct: 54  FTEPRYHVRREDLGKLHRAAWWGEVPRADLIVMLRGPGINKRDKKKRTALHLACANGNSE 113

Query: 401 MVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAV 460
           +V LL+ R+C+L++ D + RT LIKAVQ +++ CA +LLQ+G +PN+ D +G TALHYAV
Sbjct: 114 VVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALMLLQHGTDPNLPDMYGNTALHYAV 173

Query: 461 YNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRS 520
           YNED  M + LL +G +IE  +K    PLL AV  +K +MV+FL+KKKAN+NA+D  GR+
Sbjct: 174 YNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFLIKKKANLNALDRFGRT 233

Query: 521 ALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYED 580
           ALI AV  G   IV LLLQ NIDV S+D F + A DYA+ + + +I  L+ +YK  +   
Sbjct: 234 ALILAVRCGSASIVSLLLQQNIDVFSQDVFGQTAEDYAVSSHHSIICQLLSDYKENQ--- 290

Query: 581 LPINSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKD 637
           +P NS+  S+ +Q  LK TS +E         +K  + S      ++P +    D++
Sbjct: 291 MPNNSSGNSNPEQD-LKLTSEEEPQ------RLKGSENSQHEKVTQEPDINKDCDRE 340


>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
          Length = 917

 Score =  229 bits (583), Expect = 9e-60
 Identities = 138/339 (40%), Positives = 198/339 (58%), Gaps = 5/339 (1%)

Query: 327 RERWPTLMERLCSDGFAFPHYYIKPYHLKRIHRAVLHGNLEK-LKYLLLTYYDANKRDRK 385
           R R  T  +    DGF+ P Y ++   L  IH+A + G++ K ++ +LL   D N RD+K
Sbjct: 12  RRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKK 71

Query: 386 ERTALHLACATGQPEMVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANP 445
            RTAL LACA G+P +V  LV+R+C+LNL D E+RT LIKAVQ ++E CA++LL++GANP
Sbjct: 72  NRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANP 131

Query: 446 NITDFFGRTALHYAVYNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLL 505
           N+ D +G TALHYA+ NE+ SM  KLL++G +IE  S+  +  LL AV+R+K +MV FLL
Sbjct: 132 NVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLL 191

Query: 506 KKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRV 565
           KKK ++ AID  GR+ALI A   G   +V  LLQHNIDV  +D     A DYA+ +K + 
Sbjct: 192 KKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQA 251

Query: 566 IFDLIYEYKRKRYEDLPINSN---PVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTV 622
           I  +I EYK  +      NSN    +    +   +   G E S   +  ++K  +     
Sbjct: 252 IRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKME 311

Query: 623 SSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVE 661
            S+   A  D+ + +D V     +IK+ +      P  E
Sbjct: 312 VSRNVHA-DDSDNYNDDVDELIHKIKNRKPDNHQSPGKE 349


>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
           sapiens]
          Length = 917

 Score =  229 bits (583), Expect = 9e-60
 Identities = 138/339 (40%), Positives = 198/339 (58%), Gaps = 5/339 (1%)

Query: 327 RERWPTLMERLCSDGFAFPHYYIKPYHLKRIHRAVLHGNLEK-LKYLLLTYYDANKRDRK 385
           R R  T  +    DGF+ P Y ++   L  IH+A + G++ K ++ +LL   D N RD+K
Sbjct: 12  RRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKK 71

Query: 386 ERTALHLACATGQPEMVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANP 445
            RTAL LACA G+P +V  LV+R+C+LNL D E+RT LIKAVQ ++E CA++LL++GANP
Sbjct: 72  NRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANP 131

Query: 446 NITDFFGRTALHYAVYNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLL 505
           N+ D +G TALHYA+ NE+ SM  KLL++G +IE  S+  +  LL AV+R+K +MV FLL
Sbjct: 132 NVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLL 191

Query: 506 KKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRV 565
           KKK ++ AID  GR+ALI A   G   +V  LLQHNIDV  +D     A DYA+ +K + 
Sbjct: 192 KKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQA 251

Query: 566 IFDLIYEYKRKRYEDLPINSN---PVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTV 622
           I  +I EYK  +      NSN    +    +   +   G E S   +  ++K  +     
Sbjct: 252 IRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKME 311

Query: 623 SSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVE 661
            S+   A  D+ + +D V     +IK+ +      P  E
Sbjct: 312 VSRNVHA-DDSDNYNDDVDELIHKIKNRKPDNHQSPGKE 349


>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
           sapiens]
          Length = 917

 Score =  228 bits (580), Expect = 2e-59
 Identities = 141/340 (41%), Positives = 201/340 (59%), Gaps = 7/340 (2%)

Query: 327 RERWPTLMERLCSDGFAFPHYYIKPYHLKRIHRAVLHGNLEK-LKYLLLTYYDANKRDRK 385
           R R  T  +    DGF+ P Y ++   L  IH+A + G++ K ++ +LL   D N RD+K
Sbjct: 12  RRRMATWRKNRDKDGFSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKK 71

Query: 386 ERTALHLACATGQPEMVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANP 445
            RTAL LACA G+P +V  LV+R+C+LNL D E+RT LIKAVQ ++E CA++LL++GANP
Sbjct: 72  NRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANP 131

Query: 446 NITDFFGRTALHYAVYNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLL 505
           N+ D +G TALHYA+ NE+ SM  KLL++G +IE  S+  +  LL AV+R+K +MV FLL
Sbjct: 132 NVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVAFLL 191

Query: 506 KKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRV 565
           KKK ++ AID  GR+ALI A   G   +V  LLQHNIDV  +D     A DYA+ +K + 
Sbjct: 192 KKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQA 251

Query: 566 IFDLIYEYK-RKRYEDLPINSN---PVSSQKQPALKATSGKEDSISNIATEIKDGQKSGT 621
           I  +I EYK  KR + L  NSN    +    +   +   G E S   +  ++K  +    
Sbjct: 252 IRGMISEYKANKRCKSLQ-NSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKM 310

Query: 622 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVE 661
             S+   A  D+ + +D V     +IK+ +      P  E
Sbjct: 311 EVSRNVHA-DDSDNYNDDVDELIHKIKNRKPDNHQSPGKE 349


>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
           polyclonal antibodies [Homo sapiens]
          Length = 1430

 Score =  226 bits (575), Expect = 8e-59
 Identities = 115/120 (95%), Positives = 119/120 (99%)

Query: 622 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 681
           VSSQKQPALKDTSDK+DSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTE+
Sbjct: 20  VSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTED 79

Query: 682 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 741
           EF+LESEIISKLYIPKRKIISPRSI+DVLPPVEEAVDRCLYLLDRFAQ VTKDKFALESE
Sbjct: 80  EFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLYLLDRFAQAVTKDKFALESE 139



 Score =  113 bits (283), Expect = 6e-25
 Identities = 65/115 (56%), Positives = 80/115 (69%)

Query: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
           VSSQKQPALKAT+ +EDS+SNIATEIKDG+KSGTVSSQKQPALK T+D++DSV N ATEI
Sbjct: 400 VSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEI 459

Query: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
           KD +KS TV    +  L  +    D+V+   TE +   +S  +S    P  K  S
Sbjct: 460 KDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATS 514



 Score =  109 bits (273), Expect = 8e-24
 Identities = 64/115 (55%), Positives = 75/115 (65%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQKQP  KATS K DS  NIATEIKDG + GTVSSQKQPALK T+D++DSVSN A
Sbjct: 363 SGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIA 422

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
           TEIKD +KSGTV    +  L  +    D+V    TE +   +SE +S    P  K
Sbjct: 423 TEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALK 477



 Score =  107 bits (268), Expect = 3e-23
 Identities = 63/118 (53%), Positives = 77/118 (65%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQKQPALKAT+ +EDS+ NIATEIKDG+KS TVSSQKQPALK T+D++DSVS  A
Sbjct: 431 SGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIA 490

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
           TEIKD +KSGTV    +  L  +    D+ +    E +    S  +S    P  K  S
Sbjct: 491 TEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATS 548



 Score =  104 bits (260), Expect = 3e-22
 Identities = 58/93 (62%), Positives = 67/93 (72%)

Query: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
           VSS KQPALKATS KE+S+ N+ATE KD Q SGTVSSQKQPALK TSDK DSVSN  TEI
Sbjct: 604 VSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEI 663

Query: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTE 680
           KD Q+SGTV    +     +  + D+V+   TE
Sbjct: 664 KDGQQSGTVSSQKQLAWKATSVKKDSVSNIATE 696



 Score =  104 bits (260), Expect = 3e-22
 Identities = 64/122 (52%), Positives = 78/122 (63%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQKQPALKATS K+DS+SNI TEIKDGQ+SGTVSSQKQ A K TS K DSVSN A
Sbjct: 635 SGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIA 694

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPR 704
           TEIKD Q  GTV    +  L  +    D+V+    E +   +S  +S      +K+I  +
Sbjct: 695 TEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKK 754

Query: 705 SI 706
            +
Sbjct: 755 KV 756



 Score =  100 bits (250), Expect = 4e-21
 Identities = 54/71 (76%), Positives = 60/71 (84%)

Query: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
           VSSQKQPA KATS  +DS+SNIATEIK+G  SGTVSSQKQPA K TSD+ DSVSN ATEI
Sbjct: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323

Query: 648 KDEQKSGTVLP 658
           K+ Q+SGTV P
Sbjct: 324 KEGQQSGTVSP 334



 Score = 97.1 bits (240), Expect = 5e-20
 Identities = 62/126 (49%), Positives = 76/126 (60%), Gaps = 2/126 (1%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSSQKQPALKAT+ +EDS+S IATEIKDG+KSGTVSS+K+PALK TSD+ DS SN  
Sbjct: 465 SETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNIT 524

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPR 704
            E KD + S TV       L  +    D+V     E +   +S  +S    P  K  + R
Sbjct: 525 REKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLK--ATR 582

Query: 705 SIKDVL 710
             KD L
Sbjct: 583 DEKDSL 588



 Score = 88.2 bits (217), Expect = 3e-17
 Identities = 62/149 (41%), Positives = 74/149 (49%), Gaps = 34/149 (22%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQ--------------------------- 617
           S  VSSQKQPA KATS ++DS+SNIATEIK+GQ                           
Sbjct: 295 SGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIA 354

Query: 618 -------KSGTVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYR 670
                  KSGTVSSQKQP  K TSDK DS  N ATEIKD  + GTV    +  L  +   
Sbjct: 355 TRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDE 414

Query: 671 PDAVAQPVTENEFSLESEIISKLYIPKRK 699
            D+V+   TE +   +S  +S    P  K
Sbjct: 415 EDSVSNIATEIKDGEKSGTVSSQKQPALK 443



 Score = 86.7 bits (213), Expect = 7e-17
 Identities = 51/107 (47%), Positives = 68/107 (63%)

Query: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
           S  VSS++ P LKAT  ++DS+ NIA   K G+K+  VSS KQPALK TSDK++SV N A
Sbjct: 567 SRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMA 626

Query: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIIS 691
           TE KDEQ SGTV    +  L  +  + D+V+   TE +   +S  +S
Sbjct: 627 TETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVS 673



 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 47/93 (50%), Positives = 58/93 (62%)

Query: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
           VSSQ+QPALKAT  ++DS+SNIA EIKDG+KSGTVS QKQ A K    K  S+ N AT I
Sbjct: 706 VSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRI 765

Query: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTE 680
               KSGT  P     L  ++   ++V    T+
Sbjct: 766 TGGWKSGTEYPENLPTLKATIENKNSVLNTATK 798



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 45/124 (36%), Positives = 61/124 (49%)

Query: 583 INSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSN 642
           + S+  SS++ P    T  + D  S  A   KD    G VSSQKQPA K TSD  DSVSN
Sbjct: 225 LTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSN 284

Query: 643 TATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
            ATEIK+   SGTV    +     +    D+V+   TE +   +S  +S       K+I 
Sbjct: 285 IATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIF 344

Query: 703 PRSI 706
            + +
Sbjct: 345 KKKV 348



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 16/57 (28%), Positives = 29/57 (50%)

Query: 594 PALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDE 650
           P LKAT   ++S+ N AT++KD Q S       + A +    + +   N   ++K++
Sbjct: 780 PTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQ 836


>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
           sapiens]
          Length = 823

 Score =  222 bits (565), Expect = 1e-57
 Identities = 142/373 (38%), Positives = 210/373 (56%), Gaps = 31/373 (8%)

Query: 347 YYIKPYHLKRIHRAVLHGNLEKLKYLLLTYY-DANKRDRKERTALHLACATGQPEMVHLL 405
           Y I+   L++IHRA + G+  +++  L     D +  D++ RTALHLACA+G  ++V LL
Sbjct: 27  YRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASGHVQVVTLL 86

Query: 406 VSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDT 465
           V+R+C++++CD+E+RTPLI+AV  ++EACA +LL++GANPN+ D +G TALHYAVY+E T
Sbjct: 87  VNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSEST 146

Query: 466 SMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHA 525
           S+ EKLLSHG +IE   K    PLLFA+  +K KMVEFLLK+KA+ +A+D L RSAL+ A
Sbjct: 147 SLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRLRRSALMLA 206

Query: 526 VTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRK--------- 576
           V      IV +LL+ NIDV ++D   + A DYAI      I   I E+K+K         
Sbjct: 207 VYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKKEKSDV 266

Query: 577 ---------RYEDLPINSNPVSSQKQPAL--------KATSGKEDSISNIATEIKDGQKS 619
                     + +L ++S P S  K   +        K +     S       I +GQ  
Sbjct: 267 GSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGE 326

Query: 620 GTVSSQKQPALKDTSDKDDSVSNTATEIKDEQ--KSGTVLPAVEQCLNRSLYRPDAVAQP 677
           G  +  K P+LK +++ +D     A + K+ Q  ++   LP   +       R +     
Sbjct: 327 GPPA--KHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQ 384

Query: 678 VTENEFSLESEII 690
           V E   + +SE I
Sbjct: 385 VKEGNNTNKSEKI 397


>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
           sapiens]
          Length = 823

 Score =  222 bits (565), Expect = 1e-57
 Identities = 142/373 (38%), Positives = 210/373 (56%), Gaps = 31/373 (8%)

Query: 347 YYIKPYHLKRIHRAVLHGNLEKLKYLLLTYY-DANKRDRKERTALHLACATGQPEMVHLL 405
           Y I+   L++IHRA + G+  +++  L     D +  D++ RTALHLACA+G  ++V LL
Sbjct: 27  YRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASGHVQVVTLL 86

Query: 406 VSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDT 465
           V+R+C++++CD+E+RTPLI+AV  ++EACA +LL++GANPN+ D +G TALHYAVY+E T
Sbjct: 87  VNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSEST 146

Query: 466 SMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHA 525
           S+ EKLLSHG +IE   K    PLLFA+  +K KMVEFLLK+KA+ +A+D L RSAL+ A
Sbjct: 147 SLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRLRRSALMLA 206

Query: 526 VTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRK--------- 576
           V      IV +LL+ NIDV ++D   + A DYAI      I   I E+K+K         
Sbjct: 207 VYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKKEKSDV 266

Query: 577 ---------RYEDLPINSNPVSSQKQPAL--------KATSGKEDSISNIATEIKDGQKS 619
                     + +L ++S P S  K   +        K +     S       I +GQ  
Sbjct: 267 GSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGE 326

Query: 620 GTVSSQKQPALKDTSDKDDSVSNTATEIKDEQ--KSGTVLPAVEQCLNRSLYRPDAVAQP 677
           G  +  K P+LK +++ +D     A + K+ Q  ++   LP   +       R +     
Sbjct: 327 GPPA--KHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQ 384

Query: 678 VTENEFSLESEII 690
           V E   + +SE I
Sbjct: 385 VKEGNNTNKSEKI 397


>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
           sapiens]
          Length = 823

 Score =  222 bits (565), Expect = 1e-57
 Identities = 142/373 (38%), Positives = 211/373 (56%), Gaps = 31/373 (8%)

Query: 347 YYIKPYHLKRIHRAVLHGNLEKLKYLLLTYY-DANKRDRKERTALHLACATGQPEMVHLL 405
           Y I+   L++IHRA + G+  +++  L     + +  D++ RTALHLACA+G  ++V LL
Sbjct: 27  YRIRDSELQKIHRAAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASGHVQVVTLL 86

Query: 406 VSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDT 465
           V+R+C++++CD+E+RTPLI+AV  ++EACA +LL++GANPN+ D +G TALHYAVY+E T
Sbjct: 87  VNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSEST 146

Query: 466 SMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHA 525
           S+ EKLLSHG +IE   K    PLLFA+  +K KMVEFLLKKKA+ +A+D L RSAL+ A
Sbjct: 147 SLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRLRRSALMLA 206

Query: 526 VTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRK--------- 576
           V      IV +LL+ NIDV ++D   + A DYAI      I   I E+K+K         
Sbjct: 207 VYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKKEKSDV 266

Query: 577 ---------RYEDLPINSNPVSSQKQPAL--------KATSGKEDSISNIATEIKDGQKS 619
                     + +L ++S P S  K   +        K +     S       I +GQ  
Sbjct: 267 GSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGE 326

Query: 620 GTVSSQKQPALKDTSDKDDSVSNTATEIKDEQ--KSGTVLPAVEQCLNRSLYRPDAVAQP 677
           G  +  K P+LK +++ +D     A + K+ Q  ++   LP   +   +   R +     
Sbjct: 327 GPPA--KHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQQRHERSEKKQPQ 384

Query: 678 VTENEFSLESEII 690
           V E   + +SE I
Sbjct: 385 VKEGNNTNKSEKI 397


>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
           sapiens]
          Length = 823

 Score =  221 bits (564), Expect = 1e-57
 Identities = 142/373 (38%), Positives = 209/373 (56%), Gaps = 31/373 (8%)

Query: 347 YYIKPYHLKRIHRAVLHGNLEKLKYLLLTYY-DANKRDRKERTALHLACATGQPEMVHLL 405
           Y I+   L++IHRA + G+  +++  L     D +  D++ RTALHLAC +G  ++V LL
Sbjct: 27  YRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACTSGHVQVVTLL 86

Query: 406 VSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAVYNEDT 465
           V+R+C++++CD+E+RTPLI+AV  ++EACA +LL++GANPN+ D +G TALHYAVY+E T
Sbjct: 87  VNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSEST 146

Query: 466 SMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHA 525
           S+ EKLLSHG +IE   K    PLLFA+  +K KMVEFLLKKKA+ +A+D L RSAL+ A
Sbjct: 147 SLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRLRRSALMLA 206

Query: 526 VTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRK--------- 576
           V      IV +LL+ NIDV ++D   + A DYAI      I   I E+K+K         
Sbjct: 207 VYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKKEKSDV 266

Query: 577 ---------RYEDLPINSNPVSSQKQPAL--------KATSGKEDSISNIATEIKDGQKS 619
                     + +L ++S P S  K   +        K +     S       I +GQ  
Sbjct: 267 GSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGE 326

Query: 620 GTVSSQKQPALKDTSDKDDSVSNTATEIKDEQ--KSGTVLPAVEQCLNRSLYRPDAVAQP 677
           G  +  K P+LK +++ +D     A + K+ Q  ++   LP   +       R +     
Sbjct: 327 GPPA--KHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQ 384

Query: 678 VTENEFSLESEII 690
           V E   + +SE I
Sbjct: 385 VKEGNNTNKSEKI 397


>gi|52856430 protein expressed in prostate, ovary, testis, and
           placenta 15 [Homo sapiens]
          Length = 581

 Score =  221 bits (563), Expect = 2e-57
 Identities = 124/297 (41%), Positives = 186/297 (62%), Gaps = 11/297 (3%)

Query: 342 FAFPHYYIKPYHLKRIHRAVLHGNLEKLKYL-LLTYYDANKRDRKERTALHLACATGQPE 400
           F  P Y+++   L ++HRA   G + +   + +L   D NKRD+++RTALHLA A G  E
Sbjct: 128 FMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSE 187

Query: 401 MVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAV 460
           +V LL+ RRC+LN+ D + RT LIKAVQ +++ C  +LL++GA+ NI D +G TALHYA+
Sbjct: 188 VVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAI 247

Query: 461 YNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRS 520
           YNED  M + LL +G +IE  +KC   PLL  V  +K ++V+FL+KKKAN+NA+D  GR+
Sbjct: 248 YNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRT 307

Query: 521 ALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYED 580
           ALI AV  G   IV LLL+ N+DV S+D   + A +YA+ + + VI +L+ +YK K+   
Sbjct: 308 ALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQM-- 365

Query: 581 LPINSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKD 637
           L I+S   +S  +  LK TS +E      +  +K  + S      ++P +    D++
Sbjct: 366 LKISSE--NSNPEQDLKLTSEEE------SQRLKVSENSQPEKMSQEPEINKDCDRE 414


>gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo
           sapiens]
          Length = 544

 Score =  221 bits (563), Expect = 2e-57
 Identities = 124/297 (41%), Positives = 186/297 (62%), Gaps = 11/297 (3%)

Query: 342 FAFPHYYIKPYHLKRIHRAVLHGNLEKLKYL-LLTYYDANKRDRKERTALHLACATGQPE 400
           F  P Y+++   L ++HRA   G + +   + +L   D NKRD+++RTALHLA A G  E
Sbjct: 91  FMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSE 150

Query: 401 MVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAV 460
           +V LL+ RRC+LN+ D + RT LIKAVQ +++ C  +LL++GA+ NI D +G TALHYA+
Sbjct: 151 VVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAI 210

Query: 461 YNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRS 520
           YNED  M + LL +G +IE  +KC   PLL  V  +K ++V+FL+KKKAN+NA+D  GR+
Sbjct: 211 YNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRYGRT 270

Query: 521 ALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYED 580
           ALI AV  G   IV LLL+ N+DV S+D   + A +YA+ + + VI +L+ +YK K+   
Sbjct: 271 ALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQM-- 328

Query: 581 LPINSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKD 637
           L I+S   +S  +  LK TS +E      +  +K  + S      ++P +    D++
Sbjct: 329 LKISSE--NSNPEQDLKLTSEEE------SQRLKVSENSQPEKMSQEPEINKDCDRE 377


>gi|153792284 pote protein [Homo sapiens]
          Length = 584

 Score =  219 bits (559), Expect = 6e-57
 Identities = 123/297 (41%), Positives = 185/297 (62%), Gaps = 11/297 (3%)

Query: 342 FAFPHYYIKPYHLKRIHRAVLHGNLEKLKYL-LLTYYDANKRDRKERTALHLACATGQPE 400
           F  P Y+I+   L ++HRA   G + +   + +L   D NKRD+++RTALHLA A G  E
Sbjct: 128 FMEPRYHIRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLASANGNSE 187

Query: 401 MVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAV 460
           +V LL+ RRC+LN+ D + RT LIKA+Q +++ C  +LL++GA+ NI D +G TALHYA+
Sbjct: 188 VVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLMLLEHGADRNIPDEYGNTALHYAI 247

Query: 461 YNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRS 520
           YNED  M + LL +G +IE  +KC   PLL  V  +K ++V+FL+KKKAN+N +D  GR+
Sbjct: 248 YNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNVLDRYGRT 307

Query: 521 ALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYED 580
           ALI AV  G   IV LLL+ N+DV S+D   + A +YA+ + + VI +L+ +YK K+   
Sbjct: 308 ALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQM-- 365

Query: 581 LPINSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKD 637
           L I+S   +S  +  LK TS +E      +  +K  + S      ++P +    D++
Sbjct: 366 LKISSE--NSNPEQDLKLTSEEE------SQRLKVSENSQPEKMSQEPEINKDCDRE 414


>gi|239747116 PREDICTED: hypothetical protein XP_002343915 isoform 2
           [Homo sapiens]
          Length = 551

 Score =  219 bits (558), Expect = 7e-57
 Identities = 122/297 (41%), Positives = 185/297 (62%), Gaps = 11/297 (3%)

Query: 342 FAFPHYYIKPYHLKRIHRAVLHGNLEKLKYL-LLTYYDANKRDRKERTALHLACATGQPE 400
           F  P Y+++   L ++HRA   G + +   + +L   D NKRD+++RTALHLA A G  E
Sbjct: 95  FMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLASANGNSE 154

Query: 401 MVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAV 460
           +V LL+ RRC+LN+ D + RT LIKA+Q +++ C  +LL++GA+ NI D +G TALHYA+
Sbjct: 155 VVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLMLLEHGADRNIPDEYGNTALHYAI 214

Query: 461 YNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRS 520
           YNED  M + LL +G +IE  +KC   PLL  V  +K ++V+FL+KKKAN+N +D  GR+
Sbjct: 215 YNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNVLDRYGRT 274

Query: 521 ALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYED 580
           ALI AV  G   IV LLL+ N+DV S+D   + A +YA+ + + VI +L+ +YK K+   
Sbjct: 275 ALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQM-- 332

Query: 581 LPINSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKD 637
           L I+S   +S  +  LK TS +E      +  +K  + S      ++P +    D++
Sbjct: 333 LKISSE--NSNPEQDLKLTSEEE------SQRLKVSENSQPEKMSQEPEINKDCDRE 381


>gi|239747114 PREDICTED: hypothetical protein XP_002343914 isoform 1
           [Homo sapiens]
          Length = 584

 Score =  219 bits (558), Expect = 7e-57
 Identities = 122/297 (41%), Positives = 185/297 (62%), Gaps = 11/297 (3%)

Query: 342 FAFPHYYIKPYHLKRIHRAVLHGNLEKLKYL-LLTYYDANKRDRKERTALHLACATGQPE 400
           F  P Y+++   L ++HRA   G + +   + +L   D NKRD+++RTALHLA A G  E
Sbjct: 128 FMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLASANGNSE 187

Query: 401 MVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAV 460
           +V LL+ RRC+LN+ D + RT LIKA+Q +++ C  +LL++GA+ NI D +G TALHYA+
Sbjct: 188 VVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVLMLLEHGADRNIPDEYGNTALHYAI 247

Query: 461 YNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRS 520
           YNED  M + LL +G +IE  +KC   PLL  V  +K ++V+FL+KKKAN+N +D  GR+
Sbjct: 248 YNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNVLDRYGRT 307

Query: 521 ALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYED 580
           ALI AV  G   IV LLL+ N+DV S+D   + A +YA+ + + VI +L+ +YK K+   
Sbjct: 308 ALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQM-- 365

Query: 581 LPINSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKD 637
           L I+S   +S  +  LK TS +E      +  +K  + S      ++P +    D++
Sbjct: 366 LKISSE--NSNPEQDLKLTSEEE------SQRLKVSENSQPEKMSQEPEINKDCDRE 414


>gi|209977003 ANKRD26-like family C, member 3 [Homo sapiens]
          Length = 545

 Score =  218 bits (556), Expect = 1e-56
 Identities = 135/358 (37%), Positives = 204/358 (56%), Gaps = 36/358 (10%)

Query: 342 FAFPHYYIKPYHLKRIHRAVLHGNLEKLKYL-LLTYYDANKRDRKERTALHLACATGQPE 400
           F  P Y+++   L ++HRA   G + +   + +L   D NK+D+++RTALHLA A G  E
Sbjct: 165 FMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANGNSE 224

Query: 401 MVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAV 460
           +V LL+ RRC+LN+ D + RT L KAVQ +++ CA +LL++G +PNI D +G TALHYA+
Sbjct: 225 VVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTALHYAI 284

Query: 461 YNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRS 520
           YNED  M + LL +G +IE  +K    PLL  V  +K ++V+FL+KKKAN+NA+D  GR+
Sbjct: 285 YNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRT 344

Query: 521 ALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYED 580
           ALI AV  G   IV LLL+ NIDV S+D   + A +YA+ +++ VI  L+ +YK K+   
Sbjct: 345 ALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSDYKEKQI-- 402

Query: 581 LPINSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDK---- 636
           L ++S   +S  +  LK TS +E      +  +K  + S      ++P +    D+    
Sbjct: 403 LKVSSE--NSNPEQDLKLTSEEE------SQRLKGSENSQPEEMSQEPEINKGGDRKVEE 454

Query: 637 ------------DDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENE 682
                        ++++N AT   D    G + P       R    P++   P TENE
Sbjct: 455 EMKKHGSTHMGFPENLTNGAT--ADNGDDGLIPP-------RKSRTPESQQFPDTENE 503


>gi|212549546 ANKRD26-like family B, member 2 [Homo sapiens]
          Length = 542

 Score =  218 bits (556), Expect = 1e-56
 Identities = 123/297 (41%), Positives = 185/297 (62%), Gaps = 11/297 (3%)

Query: 342 FAFPHYYIKPYHLKRIHRAVLHGNLEKLKYL-LLTYYDANKRDRKERTALHLACATGQPE 400
           F  P Y+++   L ++HRA   G + +   + +L   D NKRD+++RTALHLA A G  E
Sbjct: 128 FMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSE 187

Query: 401 MVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAV 460
           +V LL+ RRC+LN+ D + RT LIKAVQ +++ C  +LL++GA+ NI D +G T LHYAV
Sbjct: 188 VVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADQNIPDEYGNTTLHYAV 247

Query: 461 YNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRS 520
           +NED  M + LL +G +IE  +KC   PLL  V  +K ++V+FL+KKKAN+NA+D  GR+
Sbjct: 248 HNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRT 307

Query: 521 ALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYED 580
           ALI AV  G   IV LLL+ N+DV S+D   + A +YA+ + + VI +L+ +YK K+   
Sbjct: 308 ALILAVCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQM-- 365

Query: 581 LPINSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKD 637
           L I+S   +S  +  LK TS +E      +  +K  + S      ++P +    D++
Sbjct: 366 LKISSE--NSNPEQDLKLTSEEE------SQRLKVSENSQPEKMSQEPEINKDCDRE 414


>gi|52856434 POTE ankyrin domain family, member G [Homo sapiens]
          Length = 508

 Score =  218 bits (555), Expect = 2e-56
 Identities = 123/296 (41%), Positives = 183/296 (61%), Gaps = 11/296 (3%)

Query: 342 FAFPHYYIKPYHLKRIHRAVLHGNLEKLKYL-LLTYYDANKRDRKERTALHLACATGQPE 400
           F  P Y+++   L ++HRA   G + +   + +L   D NK+D+++RTALHLA A G  E
Sbjct: 128 FMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANGNSE 187

Query: 401 MVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAV 460
           +V LL+ RRC+LN+ D + RT L KAVQ R++ CA +LL++G +PNI D +G TALHYA+
Sbjct: 188 VVKLLLDRRCQLNILDNKKRTALTKAVQCREDECALMLLEHGTDPNIPDEYGNTALHYAI 247

Query: 461 YNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRS 520
           YNED  M + LL +G +IE  +K    PLL  V  +K ++V+FL+KKKAN+NA+D  GR+
Sbjct: 248 YNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRT 307

Query: 521 ALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYED 580
           ALI AV  G   IV LLL+ NIDV S+D   + A +YA+ + + VI  L+ +YK K+   
Sbjct: 308 ALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHNVICQLLSDYKEKQM-- 365

Query: 581 LPINSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDK 636
           L ++S   +S  +  LK TS +E      +  +K  + S      ++P +    D+
Sbjct: 366 LKVSSE--NSNPEQDLKLTSEEE------SQRLKGSENSQPEEMSQEPEINKGGDR 413


>gi|153791352 prostate, ovary, testis expressed protein on
           chromosome 2 [Homo sapiens]
          Length = 1075

 Score =  217 bits (553), Expect = 3e-56
 Identities = 123/297 (41%), Positives = 183/297 (61%), Gaps = 11/297 (3%)

Query: 342 FAFPHYYIKPYHLKRIHRAVLHGNLEKLKYL-LLTYYDANKRDRKERTALHLACATGQPE 400
           F  P Y+++   L ++HRA   G + +   + +L   D NK+D+++RTALHLA A G  E
Sbjct: 128 FMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQKRTALHLASANGNSE 187

Query: 401 MVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAV 460
           +V LL+ RRC+LN+ D + RT LIKAVQ +++ CA +LL++G +PNI D +G T LHYA+
Sbjct: 188 VVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAI 247

Query: 461 YNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRS 520
           YNED  M + LL +G +IE  +K    PLL  V  +K ++V+FL+KKKAN+NA+D  GR+
Sbjct: 248 YNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRT 307

Query: 521 ALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYED 580
           ALI AV  G   IV LLL+ NIDV S+D   + A +YA+ + + VI  L+ +YK K+   
Sbjct: 308 ALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQM-- 365

Query: 581 LPINSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKD 637
           L I+S   +S  +  LK TS +E      +   K  + S      ++P +    D++
Sbjct: 366 LKISSE--NSNPEQDLKLTSEEE------SQRFKGSENSQPEKMSQEPEINKDGDRE 414


>gi|224282147 prostate-specific P704P [Homo sapiens]
          Length = 508

 Score =  216 bits (550), Expect = 6e-56
 Identities = 121/296 (40%), Positives = 183/296 (61%), Gaps = 11/296 (3%)

Query: 342 FAFPHYYIKPYHLKRIHRAVLHGNLEKLKYL-LLTYYDANKRDRKERTALHLACATGQPE 400
           F  P Y+++   L ++HRA   G + +   + +L   D NK+D+++RTALHLA A G  E
Sbjct: 128 FMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANGNSE 187

Query: 401 MVHLLVSRRCELNLCDREDRTPLIKAVQLRQEACATLLLQNGANPNITDFFGRTALHYAV 460
           +V LL+ RRC+LN+ D + RT L KAVQ +++ CA +LL++G +PNI D +G TALHYA+
Sbjct: 188 VVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTALHYAI 247

Query: 461 YNEDTSMIEKLLSHGTNIEECSKCEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRS 520
           YNED  M + LL +G +IE  +K    PLL  V  +K ++V+FL+KKKAN+NA+D  GR+
Sbjct: 248 YNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRT 307

Query: 521 ALIHAVTLGEKDIVILLLQHNIDVLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYED 580
            LI AV  G   IV LLL+ NIDV S+D   + A +YA+ +++ VI  L+ +YK K+   
Sbjct: 308 VLILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVICQLLSDYKEKQI-- 365

Query: 581 LPINSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDK 636
           L ++S   +S  +  LK TS +E      +  +K  + S      ++P +    D+
Sbjct: 366 LKVSSE--NSNPEQDLKLTSEEE------SQRLKGSENSQPEEMSQEPEINKGGDR 413


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,279,838
Number of Sequences: 37866
Number of extensions: 1749465
Number of successful extensions: 12158
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 351
Number of HSP's successfully gapped in prelim test: 506
Number of HSP's that attempted gapping in prelim test: 8419
Number of HSP's gapped (non-prelim): 2796
length of query: 753
length of database: 18,247,518
effective HSP length: 110
effective length of query: 643
effective length of database: 14,082,258
effective search space: 9054891894
effective search space used: 9054891894
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.