Guide to the Human Genome
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Search of human proteins with 239747210

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239747210 PREDICTED: hypothetical protein XP_002346689 [Homo
sapiens]
         (275 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239747210 PREDICTED: hypothetical protein XP_002346689 [Homo ...   586   e-168
gi|160707881 formin 2 [Homo sapiens]                                   63   3e-10
gi|150170670 piccolo isoform 2 [Homo sapiens]                          58   8e-09
gi|150378539 piccolo isoform 1 [Homo sapiens]                          58   8e-09
gi|117938759 GNAS complex locus XLas [Homo sapiens]                    55   5e-08
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    54   2e-07
gi|42518068 trans-golgi network protein 2 [Homo sapiens]               51   1e-06
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     51   1e-06
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    50   2e-06
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               47   1e-05
gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo sapiens]     47   2e-05
gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo sapiens]       47   2e-05
gi|222537747 hypothetical protein LOC342979 [Homo sapiens]             46   3e-05
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi...    44   2e-04
gi|150418009 transforming, acidic coiled-coil containing protein...    42   4e-04
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       41   0.001
gi|158966674 proline-rich protein HaeIII subfamily 2 [Homo sapiens]    41   0.001
gi|4826944 proline-rich protein HaeIII subfamily 2 [Homo sapiens]      41   0.001
gi|188536004 zinc finger protein 469 [Homo sapiens]                    41   0.001
gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]       41   0.001
gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II, pol...    40   0.002
gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II, pol...    40   0.002
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    40   0.002
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    40   0.002
gi|21735552 mitogen-activated protein kinase kinase kinase 12 [H...    40   0.002
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    40   0.002
gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo sapiens]    40   0.002
gi|110349721 titin isoform novex-3 [Homo sapiens]                      40   0.003
gi|239757110 PREDICTED: hypothetical protein [Homo sapiens]            39   0.004
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    39   0.006

>gi|239747210 PREDICTED: hypothetical protein XP_002346689 [Homo
           sapiens]
          Length = 275

 Score =  586 bits (1510), Expect = e-168
 Identities = 275/275 (100%), Positives = 275/275 (100%)

Query: 1   MDGWIERGNCPPAQLDGRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMD 60
           MDGWIERGNCPPAQLDGRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMD
Sbjct: 1   MDGWIERGNCPPAQLDGRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMD 60

Query: 61  RGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSR 120
           RGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSR
Sbjct: 61  RGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSR 120

Query: 121 PPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAE 180
           PPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAE
Sbjct: 121 PPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAE 180

Query: 181 LDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALP 240
           LDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALP
Sbjct: 181 LDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALP 240

Query: 241 MPPPEMLQLGAPHVQGAGDTGHSAARGEGMWVTQL 275
           MPPPEMLQLGAPHVQGAGDTGHSAARGEGMWVTQL
Sbjct: 241 MPPPEMLQLGAPHVQGAGDTGHSAARGEGMWVTQL 275


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 76/219 (34%), Positives = 78/219 (35%), Gaps = 39/219 (17%)

Query: 26   PEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDRGSHPPAELDG 85
            P P     G  PP  L      G  PP  L G    G  PP  L G    G  PP  L G
Sbjct: 977  PPPPLPGAGIPPPPPLP---GAGIPPPPPLPGA---GIPPPPPLPGA---GIPPPPPLPG 1027

Query: 86   QMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDG 145
                G  PP  L G    G  PP  L G    G  PP  L G    G  PP  L G    
Sbjct: 1028 ---AGIPPPPPLPG---AGIPPPPPLPG---AGIPPPPPLPG---AGIPPPPPLPG---A 1072

Query: 146  GSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQTDTGSRP 205
            G  PP  L G    G  PP  L G    G  PP  L G    G  PP  L G    G  P
Sbjct: 1073 GIPPPPPLPG---AGIPPPPPLPG---AGIPPPPPLPG---VGIPPPPPLPG---AGIPP 1120

Query: 206  PAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPMPPP 244
            P  L G    G  PP  L G       P   + +P PPP
Sbjct: 1121 PPPLPGA---GIPPPPPLPGAGIPPPPPLPRVGIPPPPP 1156



 Score = 32.0 bits (71), Expect = 0.60
 Identities = 64/254 (25%), Positives = 81/254 (31%), Gaps = 54/254 (21%)

Query: 1   MDGWIERGNCPPAQLDGRTGEPNSAPEPRWMDKGSC--PPAELDRQMDRGSHPPAELDGQ 58
           +DG   R  CPP           S P+ ++  + S    P  +  Q+D  SH P +    
Sbjct: 760 VDGLPGRPPCPPGA--------ESGPQTKFCSEISLIVSPRRISVQLD--SHQPTQ---S 806

Query: 59  MDRGSRPPAEL--DGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMD 116
           + +   PP+ L   GQ   GS PP  +  +             +       P  L     
Sbjct: 807 ISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPL----- 861

Query: 117 GGSRPPAELDGQMDG-GSRPPAELDGQMDGGSRPPAELDGQM-----DTGSRPPAELDGQ 170
               P  E    M G G  PP            PP  L G        T    P  L G 
Sbjct: 862 ----PCTESSSSMPGLGMVPP------------PPPPLPGMTVPTLPSTAIPQPPPLQGT 905

Query: 171 MDTGSRPPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTG 230
            +    PP  L G    G  PP  L G    G  P   L G    G  PP  L G     
Sbjct: 906 -EMLPPPPPPLPG---AGIPPPPPLPG---AGILPLPPLPGA---GIPPPPPLPGAAIPP 955

Query: 231 SRPPAELALPMPPP 244
             P     +P+PPP
Sbjct: 956 PPPLPGAGIPLPPP 969


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 58.2 bits (139), Expect = 8e-09
 Identities = 61/259 (23%), Positives = 101/259 (38%), Gaps = 51/259 (19%)

Query: 11  PPAQLDGRTGEPNSAPEPRWMDKGSCPPA--ELDRQMDRGSHPPAELDGQMDRGSRPPAE 68
           PPAQ  G     +  P P+ + +   PP   +   Q    + PP +  G      +P A+
Sbjct: 371 PPAQQTGSEKPSSEQPGPKALAQ---PPGVGKTPAQQPGPAKPPTQQVGT----PKPLAQ 423

Query: 69  LDGQMDRGSHP-PAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDG 127
             G       P P +   Q  G  + PA+  G        PG+   Q  G ++PP++L G
Sbjct: 424 QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAG--------PGKTSAQQTGPTKPPSQLPG 475

Query: 128 ------QMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAEL 181
                 Q  G ++PP     Q  G ++PP++  G     ++PP +  G        PA+ 
Sbjct: 476 PAKPPPQQPGPAKPPP----QQPGSAKPPSQQPGS----TKPPPQQPG--------PAKP 519

Query: 182 DGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPM 241
             Q    ++PP++  G     ++ P+       + ++P ++      TGS  P +     
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ------TGSGKPLQ----- 568

Query: 242 PPPEMLQLGAPHVQGAGDT 260
           PP        P  QG   T
Sbjct: 569 PPTVSPSAKQPPSQGLPKT 587



 Score = 55.1 bits (131), Expect = 7e-08
 Identities = 62/240 (25%), Positives = 97/240 (40%), Gaps = 27/240 (11%)

Query: 19  TGEPNSAP-EPRWMDKGSCPPAELDRQMDRGSHPPAEL-DGQMDRGSRP-PAELDGQMDR 75
           TG+P   P +    D    P   L R   R     A++  G+  + S P P++   Q   
Sbjct: 254 TGKPIQGPTQTPQTDHAKLP---LQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPT 310

Query: 76  GSHPPAELDGQ---MDGGSRPPAELDGQMDGGSRPPGELDG--QMDGGSRPPAELDGQMD 130
              PPA+  G      G ++PPA+  G     ++ PG +    Q  G ++PPA    Q  
Sbjct: 311 PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA----QPL 366

Query: 131 GGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPA-ELDGQMDTGSRPPAELDGQ----- 184
           G ++PPA    Q  G  +P +E  G       P   +   Q    ++PP +  G      
Sbjct: 367 GPAKPPA----QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLA 422

Query: 185 MDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPMPPP 244
              G + PA+  G T T  + P    G++      P +   Q    ++PP++L  P  PP
Sbjct: 423 QQPGLQSPAKAPGPTKTPVQQPGP--GKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 55/203 (27%), Positives = 80/203 (39%), Gaps = 32/203 (15%)

Query: 51  PPAELDGQMDRGSRPPAELDGQMDR-GSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPG 109
           PP  +  Q   G R P + DG      S  P ++  Q  G  +P   + G          
Sbjct: 215 PPKPIPKQQGPG-RDPLQQDGTPKSISSQQPEKIKSQPPGTGKP---IQGPTQTPQTDHA 270

Query: 110 ELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDG 169
           +L  Q D  SRP  +    + G S  P+     +   S+PP     Q  T  +PPA+  G
Sbjct: 271 KLPLQRDA-SRPQTKQADIVRGESVKPS-----LPSPSKPPI----QQPTPGKPPAQQPG 320

Query: 170 QMDTG---SRPPAELDG------QMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPP 220
              +    ++PPA+  G      Q     +PP +  G T    +PPA+  G     ++PP
Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTT----KPPAQPLGP----AKPP 372

Query: 221 AELDGQMDTGSRPPAELALPMPP 243
           A+  G     S  P   AL  PP
Sbjct: 373 AQQTGSEKPSSEQPGPKALAQPP 395



 Score = 33.1 bits (74), Expect = 0.27
 Identities = 48/234 (20%), Positives = 82/234 (35%), Gaps = 13/234 (5%)

Query: 15  LDGRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMD 74
           L G      S+P+P    K    P      + + S  P +   + D  + P  +L    +
Sbjct: 646 LGGDLAPVPSSPQP----KLKTAPVTTTSAVSKSSPQPQQTSPKKD--AAPKQDLSKAPE 699

Query: 75  RGSHPPAELDGQMDGGSRPPAELDGQMDGGSRP--PGELDGQMDGGSRPPAELDGQMDGG 132
               PP      + G     A+   + D  S+P  P E     +    P A+   +    
Sbjct: 700 PKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKM 759

Query: 133 SRPPAELDGQMDGGSRPP---AELDGQMDTGSRPPAELDGQMDTGSRPP-AELDGQMDTG 188
            +P  +L       ++P    +++  Q +  + PP + D    + S PP  E     D+ 
Sbjct: 760 VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSK 819

Query: 189 SRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPMP 242
           + P    D +  +   P +E  GQ         E   +  T   P  + A PMP
Sbjct: 820 AIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD-AKPMP 872



 Score = 28.5 bits (62), Expect = 6.7
 Identities = 22/82 (26%), Positives = 32/82 (39%), Gaps = 9/82 (10%)

Query: 172  DTGSRPPA--ELDGQMDTGSRPPAELDGQTDTGSRPPAEL-DGQMDRGSRPPAELDGQMD 228
            D    PPA  +    M      P  L    D  SR P +  +G   +GS+          
Sbjct: 3660 DMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQT------MTS 3713

Query: 229  TGSRPPAELALPMPPPEMLQLG 250
            +G++   +  LP PPPE +  G
Sbjct: 3714 SGAQKKVKRTLPNPPPEEISTG 3735


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 58.2 bits (139), Expect = 8e-09
 Identities = 61/259 (23%), Positives = 101/259 (38%), Gaps = 51/259 (19%)

Query: 11  PPAQLDGRTGEPNSAPEPRWMDKGSCPPA--ELDRQMDRGSHPPAELDGQMDRGSRPPAE 68
           PPAQ  G     +  P P+ + +   PP   +   Q    + PP +  G      +P A+
Sbjct: 371 PPAQQTGSEKPSSEQPGPKALAQ---PPGVGKTPAQQPGPAKPPTQQVGT----PKPLAQ 423

Query: 69  LDGQMDRGSHP-PAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDG 127
             G       P P +   Q  G  + PA+  G        PG+   Q  G ++PP++L G
Sbjct: 424 QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAG--------PGKTSAQQTGPTKPPSQLPG 475

Query: 128 ------QMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAEL 181
                 Q  G ++PP     Q  G ++PP++  G     ++PP +  G        PA+ 
Sbjct: 476 PAKPPPQQPGPAKPPP----QQPGSAKPPSQQPGS----TKPPPQQPG--------PAKP 519

Query: 182 DGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPM 241
             Q    ++PP++  G     ++ P+       + ++P ++      TGS  P +     
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ------TGSGKPLQ----- 568

Query: 242 PPPEMLQLGAPHVQGAGDT 260
           PP        P  QG   T
Sbjct: 569 PPTVSPSAKQPPSQGLPKT 587



 Score = 55.1 bits (131), Expect = 7e-08
 Identities = 62/240 (25%), Positives = 97/240 (40%), Gaps = 27/240 (11%)

Query: 19  TGEPNSAP-EPRWMDKGSCPPAELDRQMDRGSHPPAEL-DGQMDRGSRP-PAELDGQMDR 75
           TG+P   P +    D    P   L R   R     A++  G+  + S P P++   Q   
Sbjct: 254 TGKPIQGPTQTPQTDHAKLP---LQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPT 310

Query: 76  GSHPPAELDGQ---MDGGSRPPAELDGQMDGGSRPPGELDG--QMDGGSRPPAELDGQMD 130
              PPA+  G      G ++PPA+  G     ++ PG +    Q  G ++PPA    Q  
Sbjct: 311 PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA----QPL 366

Query: 131 GGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPA-ELDGQMDTGSRPPAELDGQ----- 184
           G ++PPA    Q  G  +P +E  G       P   +   Q    ++PP +  G      
Sbjct: 367 GPAKPPA----QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLA 422

Query: 185 MDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPMPPP 244
              G + PA+  G T T  + P    G++      P +   Q    ++PP++L  P  PP
Sbjct: 423 QQPGLQSPAKAPGPTKTPVQQPGP--GKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 55/203 (27%), Positives = 80/203 (39%), Gaps = 32/203 (15%)

Query: 51  PPAELDGQMDRGSRPPAELDGQMDR-GSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPG 109
           PP  +  Q   G R P + DG      S  P ++  Q  G  +P   + G          
Sbjct: 215 PPKPIPKQQGPG-RDPLQQDGTPKSISSQQPEKIKSQPPGTGKP---IQGPTQTPQTDHA 270

Query: 110 ELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDG 169
           +L  Q D  SRP  +    + G S  P+     +   S+PP     Q  T  +PPA+  G
Sbjct: 271 KLPLQRDA-SRPQTKQADIVRGESVKPS-----LPSPSKPPI----QQPTPGKPPAQQPG 320

Query: 170 QMDTG---SRPPAELDG------QMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPP 220
              +    ++PPA+  G      Q     +PP +  G T    +PPA+  G     ++PP
Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTT----KPPAQPLGP----AKPP 372

Query: 221 AELDGQMDTGSRPPAELALPMPP 243
           A+  G     S  P   AL  PP
Sbjct: 373 AQQTGSEKPSSEQPGPKALAQPP 395



 Score = 33.1 bits (74), Expect = 0.27
 Identities = 48/234 (20%), Positives = 82/234 (35%), Gaps = 13/234 (5%)

Query: 15  LDGRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMD 74
           L G      S+P+P    K    P      + + S  P +   + D  + P  +L    +
Sbjct: 646 LGGDLAPVPSSPQP----KLKTAPVTTTSAVSKSSPQPQQTSPKKD--AAPKQDLSKAPE 699

Query: 75  RGSHPPAELDGQMDGGSRPPAELDGQMDGGSRP--PGELDGQMDGGSRPPAELDGQMDGG 132
               PP      + G     A+   + D  S+P  P E     +    P A+   +    
Sbjct: 700 PKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKM 759

Query: 133 SRPPAELDGQMDGGSRPP---AELDGQMDTGSRPPAELDGQMDTGSRPP-AELDGQMDTG 188
            +P  +L       ++P    +++  Q +  + PP + D    + S PP  E     D+ 
Sbjct: 760 VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSK 819

Query: 189 SRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPMP 242
           + P    D +  +   P +E  GQ         E   +  T   P  + A PMP
Sbjct: 820 AIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD-AKPMP 872



 Score = 28.5 bits (62), Expect = 6.7
 Identities = 22/82 (26%), Positives = 32/82 (39%), Gaps = 9/82 (10%)

Query: 172  DTGSRPPA--ELDGQMDTGSRPPAELDGQTDTGSRPPAEL-DGQMDRGSRPPAELDGQMD 228
            D    PPA  +    M      P  L    D  SR P +  +G   +GS+          
Sbjct: 3660 DMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQT------MTS 3713

Query: 229  TGSRPPAELALPMPPPEMLQLG 250
            +G++   +  LP PPPE +  G
Sbjct: 3714 SGAQKKVKRTLPNPPPEEISTG 3735


>gi|117938759 GNAS complex locus XLas [Homo sapiens]
          Length = 1037

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 78/272 (28%), Positives = 99/272 (36%), Gaps = 58/272 (21%)

Query: 9   NCPPAQLDGRTGEPNS-APEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPA 67
           N PP  + G  G P+  A  P     GS P  E+       S PP E+      GS P  
Sbjct: 271 NAPPLWVPGAIGSPSQEAVRPPSNFTGSSPWMEI-------SGPPFEI------GSAPAG 317

Query: 68  ELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDG 127
             D  ++  S PP  LDG       PP ++ G  D   R             RPP E + 
Sbjct: 318 VDDTPVNMDS-PPIALDG-------PPIKVSGAPDKRER-----------AERPPVEEEA 358

Query: 128 QMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRP--------PA 179
               G+   AE       G   PA      DT +R         D+G+ P        PA
Sbjct: 359 AEMEGAADAAEGGKVPSPGYGSPAAGAASADTAARAAPAAPADPDSGATPEDPDSGTAPA 418

Query: 180 ELD-----GQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPP 234
           + D        D+G+ P A  D   D+G+ P A  D   D G+ P A  D   D G+ P 
Sbjct: 419 DPDSGAFAADPDSGAAPAAPAD--PDSGAAPDAPAD--PDSGAAPDAPAD--PDAGAAPE 472

Query: 235 AELALPMPPPEMLQLGAPHV-QGAGDTGHSAA 265
           A  A     P   +  A HV   A D G   A
Sbjct: 473 APAA-----PAAAETRAAHVAPAAPDAGAPTA 499



 Score = 35.4 bits (80), Expect = 0.054
 Identities = 78/328 (23%), Positives = 101/328 (30%), Gaps = 113/328 (34%)

Query: 8   GNCPPAQLDGRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPA 67
           G  P  +++  T  P++ P P   D  +C P E+ R   +  +P     G     S PP 
Sbjct: 42  GPSPAEEME--TEPPHNEPIPVENDGEACGPPEVSRPNFQVLNPAFREAGAHGSYSPPPE 99

Query: 68  E----------LDGQMDRGSHP--------------PAELDGQMDGGSRP---------- 93
           E          L G       P              PA ++     G+RP          
Sbjct: 100 EAMPFEAEQPSLGGFWPTLEQPGFPSGVHAGLEAFGPALMEPGAFSGARPGLGGYSPPPE 159

Query: 94  ---PAELDGQMDGG----------------------SRPPGELD-------GQMDGGSRP 121
              P E D     G                        PP E         G   G S P
Sbjct: 160 EAMPFEFDQPAQRGCSQLLLQVPDLAPGGPGAAGVPGAPPEEPQALRPAKAGSRGGYSPP 219

Query: 122 PA-----ELDGQMDGGSRPPAELD---GQMDGGSR------------------PPAELDG 155
           P      ELDG+  G   PP  L     Q+DG S+                  PP  + G
Sbjct: 220 PEETMPFELDGEGFGDDSPPPGLSRVIAQVDGSSQFAAVAASSAVRLTPAANAPPLWVPG 279

Query: 156 QMDTGS----RPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDG 211
            + + S    RPP+       TGS P  E+ G        PA +D        PP  LDG
Sbjct: 280 AIGSPSQEAVRPPSNF-----TGSSPWMEISGPPFEIGSAPAGVDDTPVNMDSPPIALDG 334

Query: 212 QMDRGSRPPAELDGQMD---TGSRPPAE 236
                  PP ++ G  D      RPP E
Sbjct: 335 -------PPIKVSGAPDKRERAERPPVE 355


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 69/271 (25%), Positives = 91/271 (33%), Gaps = 53/271 (19%)

Query: 11  PPAQLDGRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSR------ 64
           PP Q D ++  P S P      K   PP +   Q      PP +  G   +G        
Sbjct: 80  PPPQGD-KSRSPRSPP-----GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP 133

Query: 65  PPAELDGQMDRG--SHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSR-- 120
           PP +  G   +G  S  P    G+  G   PP +   Q  G   PPG+  G    G +  
Sbjct: 134 PPGKPQGPPPQGDKSRSPRSPPGKPQG---PPPQGGNQPQGPPPPPGKPQGPPPQGGKKP 190

Query: 121 ----PPAELDGQMDGGSR-------------PPAELDGQMDGGSRPPAELDGQMDTGSRP 163
               PP +  G    G +             PP +   Q  G   PP +  G    G   
Sbjct: 191 QGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 250

Query: 164 PAELDGQMDTG--SRPPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPA 221
           P    G    G    PPA+   +  +   PP +  G        P + +G   +G  PPA
Sbjct: 251 P---QGPPPPGKPQGPPAQGGSKSQSARSPPGKPQG--------PPQQEGNNPQGPPPPA 299

Query: 222 ELDGQMDTGSRPPAELALPMPPPEMLQLGAP 252
              G       PPA    P  PP   Q G P
Sbjct: 300 --GGNPQQPQAPPA--GQPQGPPRPPQGGRP 326


>gi|42518068 trans-golgi network protein 2 [Homo sapiens]
          Length = 437

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 65/266 (24%), Positives = 88/266 (33%), Gaps = 33/266 (12%)

Query: 20  GEPNSAPEPRW-MDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDRGSH 78
           G   S PEP+   D  S   AE     D  +   AE   Q D  ++  AE   Q    S 
Sbjct: 52  GSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSK 111

Query: 79  PPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAE 138
             +E     D  S+   EL    D   +   E     D  +R  AE   Q D  S+  +E
Sbjct: 112 SGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSE 171

Query: 139 L------------DGQM--DGGSRPPAELDGQMDTGSRPPAEL----DGQMDTGSRPPAE 180
                        DGQ   DG S+  AE     D  ++  AE     DG   +G+     
Sbjct: 172 AQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGP 231

Query: 181 LDGQMDTGSRPPAELDGQTDTGSRPPAELD------GQMDRGSRPPAELDGQMDTGSRPP 234
           +DG   +G+      D         P+  D         D    P A+ +   D G   P
Sbjct: 232 IDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSP 291

Query: 235 --------AELALPMPPPEMLQLGAP 252
                    E  L  PP E ++   P
Sbjct: 292 HAFKTESGEETDLISPPQEEVKSSEP 317



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 51/212 (24%), Positives = 81/212 (38%), Gaps = 10/212 (4%)

Query: 39  AELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELD 98
           A+  +     SHP  EL    D   +  AE     D  +   AE   Q D  S+  +E  
Sbjct: 116 AQTTKDSTSKSHP--ELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQ 173

Query: 99  GQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMD 158
              D  ++   +     DG S+  AE     D  ++  AE     DG ++  AE  G +D
Sbjct: 174 TTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPID 233

Query: 159 TGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSR 218
             S+  AE     D+ ++   E   + D  S+P   +   +D    P A+ +   D+G  
Sbjct: 234 GPSKSGAEEQTSKDSPNKVVPEQPSRKD-HSKP---ISNPSDNKELPKADTNQLADKGKL 289

Query: 219 PP----AELDGQMDTGSRPPAELALPMPPPEM 246
            P     E   + D  S P  E+    P  ++
Sbjct: 290 SPHAFKTESGEETDLISPPQEEVKSSEPTEDV 321



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 53/209 (25%), Positives = 75/209 (35%), Gaps = 8/209 (3%)

Query: 32  DKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGS 91
           D  S    EL    D      AE     D  +R  AE   Q D  S   +E     D  +
Sbjct: 121 DSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPN 180

Query: 92  RPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPA 151
           +  A+     DG S+   E     D  ++  AE     DG ++  AE  G +DG S+  A
Sbjct: 181 KSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGA 240

Query: 152 ELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQTDTGSRPP----A 207
           E     D+ ++   E   + D  S+P   +    D    P A+ +   D G   P     
Sbjct: 241 EEQTSKDSPNKVVPEQPSRKD-HSKP---ISNPSDNKELPKADTNQLADKGKLSPHAFKT 296

Query: 208 ELDGQMDRGSRPPAELDGQMDTGSRPPAE 236
           E   + D  S P  E+     T    P E
Sbjct: 297 ESGEETDLISPPQEEVKSSEPTEDVEPKE 325



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 53/235 (22%), Positives = 72/235 (30%), Gaps = 17/235 (7%)

Query: 12  PAQLDGRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDG 71
           P    G++G     PE      G+    + D     GS      D     G+      DG
Sbjct: 133 PKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDG 192

Query: 72  QMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDG 131
               G+      D     G+      DG    G+   G +DG    G+      D     
Sbjct: 193 SSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKV 252

Query: 132 GSRPPAELD------GQMDGGSRPPAELDGQMDTGSRPP----AELDGQMDTGSRPPAEL 181
               P+  D         D    P A+ +   D G   P     E   + D  S P  E+
Sbjct: 253 VPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEV 312

Query: 182 DGQMDTGSRPPAELDGQTDTG---SRPPAELDGQMDRGSRPPAELDGQM--DTGS 231
                T    P E +   DTG     PP E   +M  GS      +G +   TGS
Sbjct: 313 KSSEPTEDVEPKEAE-DDDTGPEEGSPPKEEKEKMS-GSASSENREGTLSDSTGS 365


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 59/227 (25%), Positives = 80/227 (35%), Gaps = 35/227 (15%)

Query: 21  EPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDRGSHPP 80
           +P   P P    +G  PP +   +  +G  PP +  G       PP + D +      PP
Sbjct: 128 QPQGPPPPPGKPQG--PPPQGGNK-PQGPPPPGKPQG-------PPPQGDNKSRSSRSPP 177

Query: 81  AELDGQMDGGSRPPAELDGQMDGGSRPPGELDG-QMDGGSRPPA-ELDGQMDGGSRPPAE 138
            +  G       PP +   Q  G   PPG+  G    GG++P      G+  G   PP +
Sbjct: 178 GKPQG-------PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQ 227

Query: 139 LDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQ 198
            D +      PP +  G    G   P            PP +  G    G  PP +  G 
Sbjct: 228 GDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ-GGNKPQGPPPPGKPQG- 285

Query: 199 TDTGSRPPAELDGQMDRGSR-PPAELDGQMDTGSRPPAELALPMPPP 244
                 PP +  G   R SR PP +  G    G   P     P PPP
Sbjct: 286 ------PPPQ-GGSKSRSSRSPPGKPQGPPPQGGNQPQG---PPPPP 322



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 62/247 (25%), Positives = 86/247 (34%), Gaps = 40/247 (16%)

Query: 21  EPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDRGSHPP 80
           +P   P P    +G  PP +   +  +G  PP +  G   +G            +   PP
Sbjct: 190 QPQGPPPPPGKPQG--PPPQGGNK-PQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPP 246

Query: 81  AELDGQMDGGSRPPAELDG-QMDGGSR-----PPGELDG-QMDGGSR------PPAELDG 127
            +   Q  G   PP +  G    GG++     PPG+  G    GGS+      PP +  G
Sbjct: 247 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQG 306

Query: 128 QMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTG--SRPPAELDGQM 185
                  PP +   Q  G   PP +  G    G   P    G    G    PP +   + 
Sbjct: 307 -------PPPQGGNQPQGPPPPPGKPQGPPPQGGNKP---QGPPPPGKPQGPPPQGGSKS 356

Query: 186 DTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPMPPPE 245
            +   PP +  G        P + +G   +G  PPA   G       PPA    P  PP 
Sbjct: 357 RSARSPPGKPQG--------PPQQEGNNPQGPPPPA--GGNPQQPQAPPA--GQPQGPPR 404

Query: 246 MLQLGAP 252
             Q G P
Sbjct: 405 PPQGGRP 411



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 44/160 (27%), Positives = 57/160 (35%), Gaps = 29/160 (18%)

Query: 93  PPAELDGQMDGGSRPPGELDG-QMDGGSR-----PPAELDGQMDGG--SRPPAELDGQMD 144
           PP +   Q  G   PPG+  G    GG++     PP +  G    G  SR P    G+  
Sbjct: 60  PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ 119

Query: 145 GGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQTDTGSR 204
           G   PP +   Q      PP +  G       PP +  G    G  PP +  G       
Sbjct: 120 G---PPPQGGNQPQGPPPPPGKPQG-------PPPQ-GGNKPQGPPPPGKPQG------- 161

Query: 205 PPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPMPPP 244
           PP + D +      PP +  G    G   P     P PPP
Sbjct: 162 PPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQG---PPPPP 198


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 56/235 (23%), Positives = 82/235 (34%), Gaps = 46/235 (19%)

Query: 21  EPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRG---SRPPAELDGQMDRGS 77
           +P   P P    +G  PP +   Q      PP + +G+  +G   S+ P    G+ +R  
Sbjct: 46  QPQRPPPPPGKPQG--PPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPER-- 101

Query: 78  HPPAELDGQMDG-------GSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMD 130
            PP +   Q  G         RPP +   Q      PPG+ +       RPP +   Q  
Sbjct: 102 -PPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPE-------RPPPQGGNQSQ 153

Query: 131 GGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMDTGSR 190
           G    P + +G       PP +   +  +   PP +  G        P + +G    G  
Sbjct: 154 GPPPHPGKPEG-------PPPQEGNKSRSARSPPGKPQG--------PPQQEGNKPQGPP 198

Query: 191 PPAELDGQTDTGSRP--PAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPMPP 243
           PP +  G    G  P  P        +G  PP +       G RPP       PP
Sbjct: 199 PPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQ-------GGRPPRPAQGQQPP 246



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 47/201 (23%), Positives = 73/201 (36%), Gaps = 23/201 (11%)

Query: 56  DGQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGG---SRPPGELD 112
           +G+  +G   P        +   PP +   Q  G   PP + +G+   G   S+ P    
Sbjct: 37  EGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHP 96

Query: 113 GQMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMD 172
           G+ +   RPP +   Q  G   PP + +       RPP +   Q      PP + +    
Sbjct: 97  GKPE---RPPPQGGNQSQGTPPPPGKPE-------RPPPQGGNQSHRPPPPPGKPERPPP 146

Query: 173 TG---SRPPAELDGQMDTGSRPPAELDGQTDTGSRP-----PAELDGQMDRGSRPPAELD 224
            G   S+ P    G+ +    PP E +      S P     P + +G   +G  PP +  
Sbjct: 147 QGGNQSQGPPPHPGKPE--GPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQ 204

Query: 225 GQMDTGSRPPAELALPMPPPE 245
           G    G  P    A P   P+
Sbjct: 205 GPPPAGGNPQQPQAPPAGKPQ 225


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 58/186 (31%), Positives = 69/186 (37%), Gaps = 29/186 (15%)

Query: 12  PAQLDGRTG-EPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELD 70
           P  + G  G   N  P P+ M  G  PP E+     RG HPP  L G   +  R P E+ 
Sbjct: 781 PRGMQGPPGPRENQGPAPQGMIMGH-PPQEM-----RGPHPPGGLLGHGPQEMRGPQEIR 834

Query: 71  GQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSR---PPGELDGQMDGGSRPPAELDG 127
           G       PP +  G M G   PP EL G     S+   P G L     GG + P    G
Sbjct: 835 GMQG----PPPQ--GSMLG---PPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQG 885

Query: 128 QMDGGSRP-----PAELDGQ----MDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPP 178
           Q +    P     P     Q    +  G R P   +GQ  TG  P     GQ     R P
Sbjct: 886 QQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQ-STGPPPLIPGLGQQGAQGRIP 944

Query: 179 AELDGQ 184
               GQ
Sbjct: 945 PLNPGQ 950



 Score = 36.2 bits (82), Expect = 0.032
 Identities = 68/252 (26%), Positives = 86/252 (34%), Gaps = 35/252 (13%)

Query: 17  GRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDRG 76
           G  G P   P P+ M           + M R   P   L  Q   G +  +   G M  G
Sbjct: 657 GPQGPPQGLPRPQDMHG--------PQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHM--G 706

Query: 77  SHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSR----PPAELDGQMDGG 132
              P    G +  G + P    G + G   PPG    Q   G R    PP     Q   G
Sbjct: 707 PQGPPGPQGHI--GPQGPPGPQGHL-GPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPG 763

Query: 133 SRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTG---SRPPAELDGQMDTGS 189
           S+    + G +  G  P   L+ +   G   P E  G    G     PP E+      G 
Sbjct: 764 SQG---IQGPVSQG--PLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEM-----RGP 813

Query: 190 RPPAELDGQTDTGSRPPAELDGQMD---RGSR--PPAELDGQMDTGSRPPAELALPMPPP 244
            PP  L G      R P E+ G      +GS   PP EL G   + S+         PPP
Sbjct: 814 HPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPP 873

Query: 245 EMLQLGAPHVQG 256
           +    G P  QG
Sbjct: 874 QGGMQGPPGPQG 885



 Score = 34.7 bits (78), Expect = 0.093
 Identities = 60/217 (27%), Positives = 79/217 (36%), Gaps = 26/217 (11%)

Query: 61  RGSRPPAELDGQ--MDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGG 118
           +G   P ++ G   M R   P   L  Q   G +  +   G M G   PPG    Q   G
Sbjct: 663 QGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHM-GPQGPPGP---QGHIG 718

Query: 119 SRPPAELDGQMDGGSRPPAELDGQMDGGSR----PPAELDGQMDTGSRPPAELDGQMDTG 174
            + P    G + G   PP     Q   G R    PP     Q   GS+    + G +  G
Sbjct: 719 PQGPPGPQGHL-GPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQG---IQGPVSQG 774

Query: 175 SRPPAELDGQMDTGSRPPAELDGQTDTG---SRPPAELDGQMDRGSRPPAELDGQMDTGS 231
             P   L+ +   G   P E  G    G     PP E+     RG  PP  L G      
Sbjct: 775 --PLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEM-----RGPHPPGGLLGHGPQEM 827

Query: 232 RPPAEL-ALPMPPPEMLQLGAPHVQGAGDTGHSAARG 267
           R P E+  +  PPP+   LG P  +  G  G  + +G
Sbjct: 828 RGPQEIRGMQGPPPQGSMLGPPQ-ELRGPPGSQSQQG 863


>gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo sapiens]
          Length = 562

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 45/177 (25%), Positives = 69/177 (38%), Gaps = 13/177 (7%)

Query: 32  DKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGS 91
           +K +  P     Q D+G   PAE     D G  P  E +       HP +  +  ++   
Sbjct: 8   EKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALE--- 64

Query: 92  RPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDG-QMDGGSRPP 150
            PPA         + PP   + Q+      P EL G+  GGS P    D  + DG   PP
Sbjct: 65  -PPAPAGA--SASTPPPPAPEAQLPPF---PRELAGRSAGGSSPEGGEDSDREDGNYCPP 118

Query: 151 AELDGQMDTGSRPPAELDGQMDTGSR--PPAELDGQMDTGSRPPAELDGQTDTGSRP 205
            + +        PP++ + +  +G R  PP  + GQ  +   P  +   Q  +  RP
Sbjct: 119 VKRERTSSLTQFPPSQSE-ERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRP 174



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 45/175 (25%), Positives = 69/175 (39%), Gaps = 20/175 (11%)

Query: 86  QMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDG 145
           Q D G + PAE     D G  P GE +    G   P +  +  ++    PPA        
Sbjct: 20  QKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALE----PPAPAGA--SA 73

Query: 146 GSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMDTGSR-PPAELDGQTDTGSR 204
            + PP   + Q+      P EL G+   GS P    D   + G+  PP + +  +     
Sbjct: 74  STPPPPAPEAQLPPF---PRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQF 130

Query: 205 PPAELDGQMDRGS----RPPAELDGQMDTGSRP---PAELALPMPPPEMLQLGAP 252
           PP++ +   +R S    +PP  + GQ  +   P   P E    +  P +LQ   P
Sbjct: 131 PPSQSE---ERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQP 182



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 41/165 (24%), Positives = 64/165 (38%), Gaps = 13/165 (7%)

Query: 58  QMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDG 117
           Q D+G + PAE     D G  P  E +    G   P +  +  ++    PP         
Sbjct: 20  QKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALE----PPAPAGA--SA 73

Query: 118 GSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSR-PPAELDGQMDTGSR 176
            + PP   + Q+      P EL G+  GGS P    D   + G+  PP + +        
Sbjct: 74  STPPPPAPEAQLPPF---PRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQF 130

Query: 177 PPAELDGQMDTGSR--PPAELDGQTDTGSRPPAELDGQMDRGSRP 219
           PP++ + +  +G R  PP  + GQ  +   P  +   Q     RP
Sbjct: 131 PPSQSE-ERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRP 174


>gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo sapiens]
          Length = 567

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 45/177 (25%), Positives = 69/177 (38%), Gaps = 13/177 (7%)

Query: 32  DKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGS 91
           +K +  P     Q D+G   PAE     D G  P  E +       HP +  +  ++   
Sbjct: 8   EKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALE--- 64

Query: 92  RPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDG-QMDGGSRPP 150
            PPA         + PP   + Q+      P EL G+  GGS P    D  + DG   PP
Sbjct: 65  -PPAPAGA--SASTPPPPAPEAQLPPF---PRELAGRSAGGSSPEGGEDSDREDGNYCPP 118

Query: 151 AELDGQMDTGSRPPAELDGQMDTGSR--PPAELDGQMDTGSRPPAELDGQTDTGSRP 205
            + +        PP++ + +  +G R  PP  + GQ  +   P  +   Q  +  RP
Sbjct: 119 VKRERTSSLTQFPPSQSE-ERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRP 174



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 45/175 (25%), Positives = 69/175 (39%), Gaps = 20/175 (11%)

Query: 86  QMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDG 145
           Q D G + PAE     D G  P GE +    G   P +  +  ++    PPA        
Sbjct: 20  QKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALE----PPAPAGA--SA 73

Query: 146 GSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMDTGSR-PPAELDGQTDTGSR 204
            + PP   + Q+      P EL G+   GS P    D   + G+  PP + +  +     
Sbjct: 74  STPPPPAPEAQLPPF---PRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQF 130

Query: 205 PPAELDGQMDRGS----RPPAELDGQMDTGSRP---PAELALPMPPPEMLQLGAP 252
           PP++ +   +R S    +PP  + GQ  +   P   P E    +  P +LQ   P
Sbjct: 131 PPSQSE---ERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQP 182



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 41/165 (24%), Positives = 64/165 (38%), Gaps = 13/165 (7%)

Query: 58  QMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDG 117
           Q D+G + PAE     D G  P  E +    G   P +  +  ++    PP         
Sbjct: 20  QKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALE----PPAPAGA--SA 73

Query: 118 GSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSR-PPAELDGQMDTGSR 176
            + PP   + Q+      P EL G+  GGS P    D   + G+  PP + +        
Sbjct: 74  STPPPPAPEAQLPPF---PRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQF 130

Query: 177 PPAELDGQMDTGSR--PPAELDGQTDTGSRPPAELDGQMDRGSRP 219
           PP++ + +  +G R  PP  + GQ  +   P  +   Q     RP
Sbjct: 131 PPSQSE-ERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRP 174


>gi|222537747 hypothetical protein LOC342979 [Homo sapiens]
          Length = 673

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 52/218 (23%), Positives = 85/218 (38%), Gaps = 22/218 (10%)

Query: 58  QMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGE--LDGQM 115
           +++  SR  AE  G    G   P  ++ +++G  R   E D +  G      E  L  + 
Sbjct: 431 KLELESRGSAEKLGTEREGGEEPLGIERKVEGHLRAEKEGDEEKRGAEEEEVEEPLGVEK 490

Query: 116 DGGSRPPAE----LDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQM 171
            GG   P      L+ +  GG      L+ +  GG          ++T      E D  +
Sbjct: 491 KGGEEEPEATKEPLEAERKGGEET---LEAEKRGGEE-------SLETEKTQGTEGDLNL 540

Query: 172 DTGSRPPAELDGQMDTGSRPPAELDGQT---DTGSRPPAELDGQM-DRGSRPPAELDGQM 227
           + GSR  +E   +    + PP E + +T     G +P  +  G + + G +P    +GQ 
Sbjct: 541 EQGSREGSESQAEEMNEAGPPLEANTETRPEKEGPQPQEKPVGALEEEGVKPQTAAEGQG 600

Query: 228 DTGSRPPAELALPMPPPEMLQLGAPHVQGAGDTGHSAA 265
             G   P  L    P PE      P +QG G + + +A
Sbjct: 601 PLGDATP--LLAETPAPEQPAECQPLLQGEGPSANPSA 636


>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 490

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 51/255 (20%), Positives = 100/255 (39%), Gaps = 36/255 (14%)

Query: 12  PAQLDGRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDG 71
           P+ L G    P+  P P        PP+++   +     PP+++         PP+++  
Sbjct: 150 PSLLSGVPSPPSDVPSPP--SDVPSPPSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPL 207

Query: 72  QMDRGSHPPAELDGQMDGGSRPPAELDG------QMDGGSRPPGELDGQMDGGSRPPAEL 125
             D  S PP+++    D  S PP+++         + G   PP ++   + G   PP+++
Sbjct: 208 LSDVPS-PPSDVPLLSDVPS-PPSDVPSLPSDVPSLSGVPSPPSDVPSLLSGVPSPPSDI 265

Query: 126 DGQMDGGS------RPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPA 179
               D  S        P+++   + G   PP+++   +     PP+++         PP+
Sbjct: 266 SPPSDVPSLLSDVPSLPSDVPSLLSGVPSPPSDVPSLLSDVPSPPSDVPS-------PPS 318

Query: 180 ELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELAL 239
           ++       S PP+++         PP+++             L G     S  P    +
Sbjct: 319 DIPLLSGVPS-PPSDVPSPPSDVPSPPSDV-----------PLLSGVPSPLSDVPLLSGV 366

Query: 240 PMPPPEMLQ-LGAPH 253
           P PP ++   L +PH
Sbjct: 367 PSPPSDVPSLLMSPH 381



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 35/180 (19%), Positives = 74/180 (41%), Gaps = 9/180 (5%)

Query: 79  PPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAE 138
           PP+++   + G    P+++            ++   + G   PP+++         PP++
Sbjct: 117 PPSDVPSLLSGVPSLPSDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSPPSDVPSPPSD 176

Query: 139 LDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMDTGSRP------P 192
           +   + G   PP+++         PP+++    D  S PP+++    D  S P      P
Sbjct: 177 VPSLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSDVPS-PPSDVPLLSDVPSPPSDVPSLP 235

Query: 193 AELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPMPPPEMLQLGAP 252
           +++   +   S PP+++   +     PP+++    D  S      +LP   P +L  G P
Sbjct: 236 SDVPSLSGVPS-PPSDVPSLLSGVPSPPSDISPPSDVPSLLSDVPSLPSDVPSLLS-GVP 293



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 29/167 (17%), Positives = 70/167 (41%), Gaps = 8/167 (4%)

Query: 87  MDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDGG 146
           + G   PP+++   + G    P ++           +++   + G   PP+++       
Sbjct: 111 LSGVPSPPSDVPSLLSGVPSLPSDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSPPSDV 170

Query: 147 SRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQTDTGSRPP 206
             PP+++   +     PP+++         PP+++    D  S PP+++   +D  S PP
Sbjct: 171 PSPPSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSDVPS-PPSDVPLLSDVPS-PP 228

Query: 207 AELDG------QMDRGSRPPAELDGQMDTGSRPPAELALPMPPPEML 247
           +++         +     PP+++   +     PP++++ P   P +L
Sbjct: 229 SDVPSLPSDVPSLSGVPSPPSDVPSLLSGVPSPPSDISPPSDVPSLL 275


>gi|150418009 transforming, acidic coiled-coil containing protein 2
           isoform a [Homo sapiens]
          Length = 2948

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 48/196 (24%), Positives = 68/196 (34%), Gaps = 29/196 (14%)

Query: 20  GEPNSAPEPRWMDKGSCPPAELDRQMDRGSHP---PAELDGQMDRGSRPPAELDGQMDRG 76
           G+P   P P   ++G     E   ++  G  P   P E   ++  G+ PP       +  
Sbjct: 484 GDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESA 543

Query: 77  SHPPAELDG-QMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRP 135
             PP   DG ++   S  PA        GSR PG+  G  +    PP       DGG   
Sbjct: 544 RGPPGPTDGAKVHEDSTSPA----VAKEGSRSPGDSPGGKEEAPEPP-------DGGD-- 590

Query: 136 PAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAEL 195
           P  L G+           D Q  +  R P     ++   S      D      ++PP + 
Sbjct: 591 PGNLQGE-----------DSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKG 639

Query: 196 D-GQTDTGSRPPAELD 210
             G TD      AE D
Sbjct: 640 GAGHTDGPHSQTAEAD 655



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 26/126 (20%), Positives = 46/126 (36%), Gaps = 7/126 (5%)

Query: 125 LDGQMDGGSRPPAELDGQMDGGSRPPAELDGQ--MDTGSRPPAELDGQMDTGSRPPA--- 179
           +D  + G  R  ++L  + +     P E+      + G     E   ++  G  PP    
Sbjct: 461 VDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPK 520

Query: 180 ELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQM--DRGSRPPAELDGQMDTGSRPPAEL 237
           E   ++  G+ PP      +++   PP   DG    +  + P    +G    G  P  + 
Sbjct: 521 EQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKE 580

Query: 238 ALPMPP 243
             P PP
Sbjct: 581 EAPEPP 586



 Score = 29.6 bits (65), Expect = 3.0
 Identities = 32/132 (24%), Positives = 49/132 (37%), Gaps = 18/132 (13%)

Query: 118  GSRPPAELDGQMDGGSRPPAELDGQMDGG---SRPPAELDGQMDTGSRPPAELDGQMDT- 173
            G +    LD +   G  PPA   G++       R    L    + G   P++  GQ D+ 
Sbjct: 2198 GPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSP 2257

Query: 174  --GSRPPAELDGQMDTGS-------RPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELD 224
              G     E D   D  S        PP +       G +P A++  +  +  + P +LD
Sbjct: 2258 AKGLSVRLEFDYSEDKSSWDNQQENPPPTK-----KIGKKPVAKMPLRRPKMKKTPEKLD 2312

Query: 225  GQMDTGSRPPAE 236
                +  R PAE
Sbjct: 2313 NTPASPPRSPAE 2324


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 67/255 (26%), Positives = 90/255 (35%), Gaps = 31/255 (12%)

Query: 33   KGSCPPAELDRQMDRGSHPPAEL----DGQMDRGSRPPAELDGQMDRGSHPP-AELDGQM 87
            K S P AEL +Q  + +  PA L         R  R    L  +   G   P + L  + 
Sbjct: 1526 KSSLPKAELFQQEQQSADKPASLPPASQASNHRDPRQARRLAAETGEGEGEPLSRLSARG 1585

Query: 88   DGGSRPPAELDGQMDG--GSRP---PGELDGQMD---GGSRPPAELDGQMDGGSRPPAEL 139
              G+ P  E D    G  G  P   P E +        G +PPA    + DG    P E 
Sbjct: 1586 AQGALP--ERDASRGGLVGQAPMPVPEEKEPASSPWASGEKPPA--GSEQDGWKAEPGE- 1640

Query: 140  DGQMDGGSRPPAELDGQMDTGSRP--PAELDGQMDTGSRPPAELDGQMDTGSRPP-AELD 196
                  G+RP    D       R   P    G +  G   P + DG+ D  + P  A  D
Sbjct: 1641 ------GTRPATVGDSSARPARRVLLPTPPCGALQPGF--PLQHDGERDPFTCPGFASQD 1692

Query: 197  GQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPMPPPEMLQLGA-PHVQ 255
                +             R S P  E +G  +  +R P E   P+PPP     G+ P  Q
Sbjct: 1693 KALGSAQYEDPRNLHSAGRSSSPAGETEGDREPQAR-PGEGTAPLPPPGQKVGGSQPPFQ 1751

Query: 256  GAGDTGHSAARGEGM 270
            G  + G  A    G+
Sbjct: 1752 GQREPGPHALGMSGL 1766



 Score = 29.6 bits (65), Expect = 3.0
 Identities = 50/185 (27%), Positives = 66/185 (35%), Gaps = 31/185 (16%)

Query: 7    RGNCPPAQLDGRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRP- 65
            RG  PP+Q  G+ G P       ++      P++ +    RG H P + +G   RG  P 
Sbjct: 1904 RGGPPPSQFGGQRGPPPG----HFVGPRGPHPSQFETA--RGPH-PNQFEG--PRGQAPN 1954

Query: 66   ----PAELDGQM--DRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGS 119
                P  +  Q   D+  H P     Q     R PA L      GS P  E + Q     
Sbjct: 1955 FMPGPRGIQPQQFEDQRVHSPPRFTNQ-----RAPAPLQFGGLRGSAPFSEKNEQTPSRF 2009

Query: 120  RPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPA 179
                +    M  G RP  EL       S PP     + +    PP+ L      G  P  
Sbjct: 2010 HFQGQAPQVMKPGPRPLLELP------SHPPQHRKDRWEEAG-PPSALSSSA-PGQGP-- 2059

Query: 180  ELDGQ 184
            E DGQ
Sbjct: 2060 EADGQ 2064


>gi|158966674 proline-rich protein HaeIII subfamily 2 [Homo sapiens]
          Length = 166

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 45/155 (29%), Positives = 55/155 (35%), Gaps = 19/155 (12%)

Query: 40  ELDRQMDRGSHPPAELDG----QMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPA 95
           +LD  + +   P    DG    Q     R    L GQ    S P A    Q DG  + P 
Sbjct: 18  DLDEDVSQEDVPLVISDGGDSEQFIDEERQGPPLGGQQ---SQPSAGDGNQNDGPQQGPP 74

Query: 96  ELDGQMDGGSRPP-GELDGQMDGGSRPP-----AELDGQMDGGSRPPAELDGQMDGGSRP 149
           +  GQ   G  PP G+  G    G  PP      +   Q  G  RPP    G+  G   P
Sbjct: 75  QQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPPR---GRPQG---P 128

Query: 150 PAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQ 184
           P +   Q      PP +  G    G RP     GQ
Sbjct: 129 PQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQ 163



 Score = 34.3 bits (77), Expect = 0.12
 Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 14/125 (11%)

Query: 110 ELDGQMDGG--SRPPAELDGQMDGGSRPPAELDGQMDGGSRPP-AELDGQMDTGSRPP-- 164
           E  G   GG  S+P A    Q DG  + P +  GQ   G  PP  +  G    G  PP  
Sbjct: 45  ERQGPPLGGQQSQPSAGDGNQNDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPP 104

Query: 165 -AELDGQMDTGS--RPPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPA 221
                G    G   RPP            PP +   Q      PP +  G   +G RP  
Sbjct: 105 QGRPQGPPQQGGHPRPP------RGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQG 158

Query: 222 ELDGQ 226
              GQ
Sbjct: 159 PPQGQ 163



 Score = 32.3 bits (72), Expect = 0.46
 Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 6/70 (8%)

Query: 177 PPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPP-AELDGQMDTGSRPPA 235
           PP  L GQ    S+P A    Q D   + P +  GQ  +G  PP  +  G    G  PP 
Sbjct: 49  PP--LGGQQ---SQPSAGDGNQNDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPP 103

Query: 236 ELALPMPPPE 245
               P  PP+
Sbjct: 104 PQGRPQGPPQ 113


>gi|4826944 proline-rich protein HaeIII subfamily 2 [Homo sapiens]
          Length = 166

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 45/155 (29%), Positives = 55/155 (35%), Gaps = 19/155 (12%)

Query: 40  ELDRQMDRGSHPPAELDG----QMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPA 95
           +LD  + +   P    DG    Q     R    L GQ    S P A    Q DG  + P 
Sbjct: 18  DLDEDVSQEDVPLVISDGGDSEQFIDEERQGPPLGGQQ---SQPSAGDGNQNDGPQQGPP 74

Query: 96  ELDGQMDGGSRPP-GELDGQMDGGSRPP-----AELDGQMDGGSRPPAELDGQMDGGSRP 149
           +  GQ   G  PP G+  G    G  PP      +   Q  G  RPP    G+  G   P
Sbjct: 75  QQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPPR---GRPQG---P 128

Query: 150 PAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQ 184
           P +   Q      PP +  G    G RP     GQ
Sbjct: 129 PQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQ 163



 Score = 34.3 bits (77), Expect = 0.12
 Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 14/125 (11%)

Query: 110 ELDGQMDGG--SRPPAELDGQMDGGSRPPAELDGQMDGGSRPP-AELDGQMDTGSRPP-- 164
           E  G   GG  S+P A    Q DG  + P +  GQ   G  PP  +  G    G  PP  
Sbjct: 45  ERQGPPLGGQQSQPSAGDGNQNDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPP 104

Query: 165 -AELDGQMDTGS--RPPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPA 221
                G    G   RPP            PP +   Q      PP +  G   +G RP  
Sbjct: 105 QGRPQGPPQQGGHPRPP------RGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQG 158

Query: 222 ELDGQ 226
              GQ
Sbjct: 159 PPQGQ 163



 Score = 32.3 bits (72), Expect = 0.46
 Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 6/70 (8%)

Query: 177 PPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPP-AELDGQMDTGSRPPA 235
           PP  L GQ    S+P A    Q D   + P +  GQ  +G  PP  +  G    G  PP 
Sbjct: 49  PP--LGGQQ---SQPSAGDGNQNDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPP 103

Query: 236 ELALPMPPPE 245
               P  PP+
Sbjct: 104 PQGRPQGPPQ 113


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 64/249 (25%), Positives = 90/249 (36%), Gaps = 35/249 (14%)

Query: 22  PNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDRGSHPPA 81
           P  AP P     G   P ++       S PP E +    R ++   E  GQ      P A
Sbjct: 6   PRGAPPPTMT--GDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEA 63

Query: 82  ELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDG---GSRPPAE 138
           +     DG  +PP+ L GQ    S  PG+         R P +   ++ G   GS P   
Sbjct: 64  QPRQARDGELKPPS-LRGQ--APSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRY 120

Query: 139 LDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQ 198
           + G     ++P  +     +T   P      Q++    P  E+D     G+  P    G 
Sbjct: 121 ILGIASSRTKPTLD-----ETPENP------QLEAAQLP--EVDTPQGPGTGAPLR-PGL 166

Query: 199 TDTGSRPPAELDGQMDRGSRPPAELDGQMDTG----SRPPAELALPMPPPEM----LQLG 250
             T ++P AE  G       PP+       T      RPPA    P PP       LQ G
Sbjct: 167 PRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPA----PGPPQSRGTSPLQPG 222

Query: 251 A-PHVQGAG 258
           + P  Q +G
Sbjct: 223 SYPEYQASG 231



 Score = 31.6 bits (70), Expect = 0.79
 Identities = 33/119 (27%), Positives = 44/119 (36%), Gaps = 14/119 (11%)

Query: 148 RPPAELDGQMDT----GSRPPAELDGQ------MDTGSRPPAELDGQMDTGSRPPAELDG 197
           RPP+  DG   T     S P     GQ      +DT   PP   D ++     PPA L  
Sbjct: 383 RPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPP---DTELAAPGPPPARLPQ 439

Query: 198 QTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPMPPPEMLQLGAPHVQG 256
             D  + P     G     +R     +GQ   G R     + P+P P++L    P   G
Sbjct: 440 LWDPTAAPYPTPPGGPLAATRSMF-FNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHG 497


>gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]
          Length = 981

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 53/220 (24%), Positives = 77/220 (35%), Gaps = 15/220 (6%)

Query: 27  EPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDRGSHPPAELDGQ 86
           +P   D GS PP E+    + G+ P   L       S PPAE +  ++      AE+  +
Sbjct: 246 DPAAPDVGSVPPVEVVYSQEPGAQPDLAL-----ARSLPPAE-ELPVETPKRAGAEVSWE 299

Query: 87  MDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRP--PAELDGQMD 144
           +     PP + D      S  P   D         P++ +     G+ P  P  + G ++
Sbjct: 300 VSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVE 359

Query: 145 GGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMD-TGSRPPAELDGQTDTGS 203
               P + + G  D G   PA    +   G+  P E +       S PPA       T  
Sbjct: 360 APGTPKSLIPGPSDPG---PAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSR 416

Query: 204 RPPAELDGQMDRGSRPPAELDGQ---MDTGSRPPAELALP 240
           R    +  Q   G  PP E           S PPA    P
Sbjct: 417 RGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAP 456



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 50/205 (24%), Positives = 76/205 (37%), Gaps = 16/205 (7%)

Query: 47  RGSHPPAELDGQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSR 106
           +G H   +     D GS PP E+    + G+ P   L       S PPAE +  ++   R
Sbjct: 238 QGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLAL-----ARSLPPAE-ELPVETPKR 291

Query: 107 PPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRP--P 164
              E+  ++     PP + D      S  P   D         P++ +     G+ P  P
Sbjct: 292 AGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISP 351

Query: 165 AELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDR-GSRPPAEL 223
             + G ++    P + + G  D G   PA    ++  G+  P E +    R  S PPA  
Sbjct: 352 QRVRGAVEAPGTPKSLIPGPSDPG---PAVNRTESPMGALQPDEAEEWPGRPQSHPPAPP 408

Query: 224 DGQMDTGS----RPPAELALPMPPP 244
                T      R   + AL  PPP
Sbjct: 409 VQAPSTSRRGLIRVTTQRALGQPPP 433



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 38/133 (28%), Positives = 50/133 (37%), Gaps = 18/133 (13%)

Query: 136 PAELDGQMDGGSRPPAELDGQMDTGSR-----------PPAELDGQMDTGSRPPAELDGQ 184
           P  L  +   G  PP +   +  T SR           PP  L     T  RP  E  G 
Sbjct: 169 PPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGG 228

Query: 185 MDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPMPPP 244
            +   +  A+  G   T   P A      D GS PP E+    + G++P   LA  +PP 
Sbjct: 229 FEEHLQEAAQ--GPHFTQQDPAAP-----DVGSVPPVEVVYSQEPGAQPDLALARSLPPA 281

Query: 245 EMLQLGAPHVQGA 257
           E L +  P   GA
Sbjct: 282 EELPVETPKRAGA 294


>gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1b
           [Homo sapiens]
          Length = 867

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 57/232 (24%), Positives = 81/232 (34%), Gaps = 54/232 (23%)

Query: 6   ERGNCPPAQLDGRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRP 65
           ER   PPAQ    + E   APEP    +GSC                    G++  G RP
Sbjct: 403 ERDIWPPAQAPTSSQELAGAPEP----QGSCAQG-----------------GRVAPGQRP 441

Query: 66  PAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAEL 125
                G          +LD  +   S   +E +G     S   GE +G+  G  +P A  
Sbjct: 442 AQGATG---------TDLDFDLSSDSESSSESEGTKSSSSASDGESEGKR-GRQKPKAAP 491

Query: 126 DGQ---MDGGSRPPAELDGQMDGGSRPPA-ELDGQMDTGSRPPAELDGQMDTGSRPPAEL 181
           +G      G S  P           RP A  L G+ + G+  P   D + + G +   E 
Sbjct: 492 EGAGALAQGSSLEP----------GRPAAPSLPGEAEPGAHAP---DKEPELGGQEEGER 538

Query: 182 DGQMDTGS----RPPAELDGQTD--TGSRPPAELDGQMDRGSRPPAELDGQM 227
           DG    G+    R  AE + Q    +G      LD  M+       + D  +
Sbjct: 539 DGLCGLGNGCADRKEAETESQNSELSGVTAGESLDQSMEEEEEEDTDEDDHL 590


>gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1a
           [Homo sapiens]
          Length = 961

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 57/232 (24%), Positives = 81/232 (34%), Gaps = 54/232 (23%)

Query: 6   ERGNCPPAQLDGRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRP 65
           ER   PPAQ    + E   APEP    +GSC                    G++  G RP
Sbjct: 403 ERDIWPPAQAPTSSQELAGAPEP----QGSCAQG-----------------GRVAPGQRP 441

Query: 66  PAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDGQMDGGSRPPAEL 125
                G          +LD  +   S   +E +G     S   GE +G+  G  +P A  
Sbjct: 442 AQGATG---------TDLDFDLSSDSESSSESEGTKSSSSASDGESEGKR-GRQKPKAAP 491

Query: 126 DGQ---MDGGSRPPAELDGQMDGGSRPPA-ELDGQMDTGSRPPAELDGQMDTGSRPPAEL 181
           +G      G S  P           RP A  L G+ + G+  P   D + + G +   E 
Sbjct: 492 EGAGALAQGSSLEP----------GRPAAPSLPGEAEPGAHAP---DKEPELGGQEEGER 538

Query: 182 DGQMDTGS----RPPAELDGQTD--TGSRPPAELDGQMDRGSRPPAELDGQM 227
           DG    G+    R  AE + Q    +G      LD  M+       + D  +
Sbjct: 539 DGLCGLGNGCADRKEAETESQNSELSGVTAGESLDQSMEEEEEEDTDEDDHL 590


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 59/246 (23%), Positives = 92/246 (37%), Gaps = 16/246 (6%)

Query: 38   PAELDRQMDRGS-HPPAELDGQMDRGS--RPPAELDGQMDRGSHPPAELDGQMD-GGSRP 93
            P   ++ ++ G   PP   +  ++ G    P A     ++ G  PP   D   + GG R 
Sbjct: 981  PEREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRF 1040

Query: 94   PAELDGQMDGGS-RPPGELDGQMDGGSRPPA----ELDGQMDGGSRPPAELDGQMDGGSR 148
            P   +   + G  R PG  +   +     P       +  ++    P A +  + +GG  
Sbjct: 1041 PRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAPAPSAVVSSR-NGGET 1099

Query: 149  PPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQTDTGSRPPAE 208
             P  L      G+  P       +TG  P A   G++D GS   A +   T  G  P + 
Sbjct: 1100 APGPLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSG 1159

Query: 209  LD---GQMD--RGSRPPAELDGQMDTGSRPPAELALPMPPPEMLQLGAPHVQGAGDTGHS 263
            +D   G +D  R   PP  L    +   R   E A P   PE+   G P    +   G +
Sbjct: 1160 VDAKAGWVDNTRPQPPPPPLPPPPEAQPR-RLEPAPPRARPEVAPEGEPGAPDSRAGGDT 1218

Query: 264  AARGEG 269
            A  G+G
Sbjct: 1219 ALSGDG 1224


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 61/259 (23%), Positives = 82/259 (31%), Gaps = 53/259 (20%)

Query: 44  QMDRGSHPPAELDGQMDRGS--------RP-----PAELDGQMDRGSHP-PAELDGQMDG 89
           Q  R   PP + +G+  +G         RP     P    G   +G  P P + +GQ   
Sbjct: 46  QPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQ 105

Query: 90  GSR--------------PPAELDGQMDGGSRPPGELDGQMDGG---SRPPAELDGQMDGG 132
           G                PP +   Q  G    PG+ +G    G   S+ P    G+ +G 
Sbjct: 106 GGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEG- 164

Query: 133 SRPPAELDGQMDGGSRPPAELDGQMDTGS--------RP-----PAELDGQMDTGSRP-P 178
             PP +   Q  G    P + +G    G         RP     P    G    G  P P
Sbjct: 165 --PPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP 222

Query: 179 AELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRP----P 234
            + +G    G   P            PP + +G   +   PP    G    G  P    P
Sbjct: 223 GKPEGPPSQGGNKPQGPPPHPGKPQGPPPQ-EGNKPQRPPPPGRPQGPPPPGGNPQQPLP 281

Query: 235 AELALPMPPPEMLQLGAPH 253
                P  PP   Q G PH
Sbjct: 282 PPAGKPQGPPPPPQGGRPH 300


>gi|21735552 mitogen-activated protein kinase kinase kinase 12 [Homo
           sapiens]
          Length = 859

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 71/266 (26%), Positives = 92/266 (34%), Gaps = 40/266 (15%)

Query: 21  EPNSAPEPRWMDKG-----SCPPAELDRQMD-----RGSHPPAELDGQMDRGSRPPAELD 70
           EP     P  +  G     +CPPA      D       S  P  L   +  GSR      
Sbjct: 570 EPGGPGSPGGLGGGPSAWEACPPALRGLHHDLLLRKMSSSSPDLLSAAL--GSRGRGATG 627

Query: 71  GQMDRGSHPPAELDGQMDGGSRPPAELDGQMDG--GSRP----PGELDGQMDGGSRPPAE 124
           G  D GS PPA  D     GS P +       G  G  P    PGE  G +  G    + 
Sbjct: 628 GAGDPGSPPPARGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGVGLLGTGREGTSG 687

Query: 125 LDGQMDGGSR-PPAEL-------DGQMDG--GSRPPAELDGQMD--TGSRPPAELDGQMD 172
             G   G     PA L         Q  G        E+D +++  +  R P  L+ +  
Sbjct: 688 RGGSRAGSQHLTPAALLYRAAVTRSQKRGISSEEEEGEVDSEVELTSSQRWPQSLNMRQS 747

Query: 173 T---GSRPPAELDGQMDTGSRPPAELD---GQTDTGSRPPAELDGQMDRGSRPPAELDGQ 226
                S  P+  DG+  T S P        G T+T  RP    D    +GS  P  LD  
Sbjct: 748 LSTFSSENPS--DGEEGTASEPSPSGTPEVGSTNTDERPDERSDDMCSQGSEIP--LDPP 803

Query: 227 MDTGSRPPAELALPMPPPEMLQLGAP 252
                  P   +LP+P  E+L+   P
Sbjct: 804 PSEVIPGPEPSSLPIPHQELLRERGP 829



 Score = 31.6 bits (70), Expect = 0.79
 Identities = 26/82 (31%), Positives = 28/82 (34%), Gaps = 11/82 (13%)

Query: 188 GSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTGSRPPAELALPMPPPEML 247
           GSR      G  D GS PPA       RG  PP+E      T    P       PPP   
Sbjct: 619 GSRGRGATGGAGDPGSPPPA-------RGDTPPSEGSAPGSTSPDSPGGAKGEPPPP--- 668

Query: 248 QLGAPHVQGAGDTGHSAARGEG 269
            +G     G   TG     G G
Sbjct: 669 -VGPGEGVGLLGTGREGTSGRG 689


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 73/279 (26%), Positives = 83/279 (29%), Gaps = 42/279 (15%)

Query: 11  PPAQLDGRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELD 70
           P   + G  G P     PR +     PP   D   D    P      +   G  P     
Sbjct: 647 PGGPMPGPHGGPGGPVGPRLLGPPP-PPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHR 705

Query: 71  GQMDRGSH----PPAELDGQMDG--GSRPP----AELDGQMDGGSRPPGELDGQMDG--- 117
           G+  RG +    PP    G   G  G  PP        G + GG   P E  G   G   
Sbjct: 706 GRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSS 765

Query: 118 GSRPPAELDGQMDGGSRPPAELDGQMDGGS--RPPAELDGQMDTGS--RPPAELDGQMDT 173
           G RP     G M  G RP     G M GG   RP     G +  GS  RP     G M  
Sbjct: 766 GHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGA 825

Query: 174 GS--RPPAELDGQM-DTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQMDTG 230
           G   RP     G M  +G   P E  G        P ++ G      R P          
Sbjct: 826 GGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGP---------- 875

Query: 231 SRPPAELALPMPPPEMLQLGAPHVQGAGDTGHSAARGEG 269
                      PP E      P   G G  GH      G
Sbjct: 876 -----------PPHEHRGHDGPGHGGGGHRGHDGGHSHG 903



 Score = 29.3 bits (64), Expect = 3.9
 Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 1/48 (2%)

Query: 135 PPAE-LDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAEL 181
           PP+E +D    G   PP E+   MDT S  P  LD +       P +L
Sbjct: 342 PPSEAMDADRPGTPVPPVEVPELMDTASLEPGALDAKPVESPGDPNQL 389



 Score = 28.5 bits (62), Expect = 6.7
 Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 1/37 (2%)

Query: 79  PPAE-LDGQMDGGSRPPAELDGQMDGGSRPPGELDGQ 114
           PP+E +D    G   PP E+   MD  S  PG LD +
Sbjct: 342 PPSEAMDADRPGTPVPPVEVPELMDTASLEPGALDAK 378


>gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo sapiens]
          Length = 166

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 40/126 (31%), Positives = 47/126 (37%), Gaps = 17/126 (13%)

Query: 65  PPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPP-GELDGQMDGGSRPP- 122
           PP  L GQ    S P A    Q DG  + P +  GQ   G  PP G+  G    G  PP 
Sbjct: 49  PP--LGGQQ---SQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPP 103

Query: 123 ----AELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDTGSRPP 178
                +   Q  G  RPP    G+  G   PP +   Q      PP +  G    G RP 
Sbjct: 104 PQGRPQGPPQQGGHPRPPR---GRPQG---PPQQGGHQQGPPPPPPGKPQGPPPQGGRPQ 157

Query: 179 AELDGQ 184
               GQ
Sbjct: 158 GPPQGQ 163



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 38/123 (30%), Positives = 46/123 (37%), Gaps = 16/123 (13%)

Query: 35  SCPPAELDRQMDRGSHPPAELDGQMDRGSRPP-AELDGQMDRGSHPPAELDGQMDGGSRP 93
           S P A    Q D     P +  GQ  +G  PP  +  G   +G HPP    G+  G   P
Sbjct: 56  SQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPP-QGRPQG---P 111

Query: 94  PAELDGQMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAEL 153
           P     Q  G  RPP    G+  G   PP +   Q      PP +  G    G RP    
Sbjct: 112 P-----QQGGHPRPP---RGRPQG---PPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPP 160

Query: 154 DGQ 156
            GQ
Sbjct: 161 QGQ 163



 Score = 37.0 bits (84), Expect = 0.019
 Identities = 37/121 (30%), Positives = 46/121 (38%), Gaps = 17/121 (14%)

Query: 52  PAELDGQMDRGSRP-PAELDGQMDRGSHPP-AELDGQMDGGSRPPAELDGQMDGGSRPPG 109
           P+  DG  D G +  P +  GQ  +G  PP  +  G    G  PP    G+  G   PP 
Sbjct: 58  PSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPP-QGRPQG---PP- 112

Query: 110 ELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDG 169
               Q  G  RPP    G+  G   PP +   Q      PP +  G    G RP     G
Sbjct: 113 ----QQGGHPRPPR---GRPQG---PPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQG 162

Query: 170 Q 170
           Q
Sbjct: 163 Q 163



 Score = 33.5 bits (75), Expect = 0.21
 Identities = 37/130 (28%), Positives = 45/130 (34%), Gaps = 22/130 (16%)

Query: 111 LDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPP-AELDG 169
           LD +  G   PP  L GQ    S+P A    Q DG  + P +  GQ   G  PP  +  G
Sbjct: 42  LDEERQG---PP--LGGQQ---SQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQG 93

Query: 170 QMDTGSRPP---AELDGQMDTGSR----------PPAELDGQTDTGSRPPAELDGQMDRG 216
               G  PP       G    G            PP +   Q      PP +  G   +G
Sbjct: 94  PPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQG 153

Query: 217 SRPPAELDGQ 226
            RP     GQ
Sbjct: 154 GRPQGPPQGQ 163



 Score = 32.0 bits (71), Expect = 0.60
 Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 6/70 (8%)

Query: 177 PPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPP-AELDGQMDTGSRPPA 235
           PP  L GQ    S+P A    Q D   + P +  GQ  +G  PP  +  G    G  PP 
Sbjct: 49  PP--LGGQQ---SQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPP 103

Query: 236 ELALPMPPPE 245
               P  PP+
Sbjct: 104 PQGRPQGPPQ 113


>gi|110349721 titin isoform novex-3 [Homo sapiens]
          Length = 5604

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 15/97 (15%)

Query: 16   DGRTGEPNSAPEPRWMDKGSCPPAELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDR 75
            +G  GE  S P    +++ S PP E    ++R S PP E    ++R S PP E    ++R
Sbjct: 5044 EGEVGERYSTPPGETLERYSTPPGE---TLERYSTPPGE---TLERYSTPPGE---TLER 5094

Query: 76   GSHPPAELDGQMDGGSRPPAELDGQMD---GGSRPPG 109
             S PP E    ++  S PP E   +     GG  P G
Sbjct: 5095 YSTPPGE---TLERYSTPPGEALERYSIPTGGPNPTG 5128


>gi|239757110 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 192

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 47/162 (29%), Positives = 59/162 (36%), Gaps = 21/162 (12%)

Query: 57  GQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGS--RPPAELDGQMDGGSRPPGELDGQ 114
           G+  +  R PA     + R SHPP         GS  + PAEL  Q+   + PPG   G 
Sbjct: 26  GRPHQARRHPAAWGLPVRRPSHPPRPTTSSWANGSNRQHPAELSVQLP-ANPPPGLNQGC 84

Query: 115 MDGGSR---------PPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPA 165
           +   S          P A L G   G  R   E +GQ  G       ++ Q      P  
Sbjct: 85  IRAASAPRWVPTLTVPQATLPGGSQGHRRCRGEGEGQRRGC------VEKQPRPTPTPAC 138

Query: 166 ELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQTDTGSRPPA 207
           EL G       PP        TG+R    + G   TGS P A
Sbjct: 139 ELTGLAPAPPTPPPAWWRWARTGTR---AMGGAASTGSAPTA 177


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 39/174 (22%), Positives = 63/174 (36%)

Query: 54  ELDGQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDG 113
           E +GQ+        E +GQ+        E +GQ+        E +GQ+        E +G
Sbjct: 56  EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 115

Query: 114 QMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDT 173
           Q+        E +GQ+        E +GQ+        E +GQ+        E +GQ+  
Sbjct: 116 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 175

Query: 174 GSRPPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQM 227
                 E +GQ+        E +GQ         E + QM +      E + QM
Sbjct: 176 QEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQM 229



 Score = 37.7 bits (86), Expect = 0.011
 Identities = 43/188 (22%), Positives = 70/188 (37%), Gaps = 8/188 (4%)

Query: 40  ELDRQMDRGSHPPAELDGQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDG 99
           EL R+++    P  + +GQ+        E +GQ+        E +GQ+        E +G
Sbjct: 36  ELKRKLETDKIPLPQ-EGQVREQEGQVREQEGQVREQEGQVREQEGQV-------REQEG 87

Query: 100 QMDGGSRPPGELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDT 159
           Q+        E +GQ+        E +GQ+        E +GQ+        E +GQ+  
Sbjct: 88  QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 147

Query: 160 GSRPPAELDGQMDTGSRPPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRP 219
                 E +GQ+        E +GQ+        E +GQ         E +GQM      
Sbjct: 148 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQ 207

Query: 220 PAELDGQM 227
             E + QM
Sbjct: 208 MGEQEEQM 215



 Score = 36.6 bits (83), Expect = 0.024
 Identities = 38/174 (21%), Positives = 62/174 (35%)

Query: 54  ELDGQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDG 113
           E +GQ+        E +GQ+        E +GQ+        E +GQ+        E +G
Sbjct: 70  EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 129

Query: 114 QMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDT 173
           Q+        E +GQ+        E +GQ+        E +GQ+        E +GQ+  
Sbjct: 130 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 189

Query: 174 GSRPPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQM 227
                 E +GQM        E + Q         E + QM +      E + Q+
Sbjct: 190 QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243



 Score = 36.2 bits (82), Expect = 0.032
 Identities = 38/174 (21%), Positives = 60/174 (34%)

Query: 54  ELDGQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDG 113
           E +GQ+        E +GQ+        E +GQ+        E +GQ+        E +G
Sbjct: 98  EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 157

Query: 114 QMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDT 173
           Q+        E +GQ+        E +GQ+        E +GQM        E + QM  
Sbjct: 158 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQK 217

Query: 174 GSRPPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQM 227
                 E + QM        E + Q         + + QM +      E + QM
Sbjct: 218 QEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQM 271



 Score = 35.0 bits (79), Expect = 0.071
 Identities = 37/174 (21%), Positives = 61/174 (35%)

Query: 54  ELDGQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDG 113
           E +GQ+        E +GQ+        E +GQ+        E +GQ+        E +G
Sbjct: 84  EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 143

Query: 114 QMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDT 173
           Q+        E +GQ+        E +GQ+        E +GQ+        E +GQM  
Sbjct: 144 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGE 203

Query: 174 GSRPPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQM 227
                 E + QM        E + Q         E + Q+ +      + + QM
Sbjct: 204 QEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM 257



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 39/174 (22%), Positives = 58/174 (33%), Gaps = 8/174 (4%)

Query: 54  ELDGQMDRGSRPPAELDGQMDRGSHPPAELDGQMDGGSRPPAELDGQMDGGSRPPGELDG 113
           E +GQ+        E +GQ+        E +GQ+        E +GQM       GE +G
Sbjct: 147 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQM-------GEQEG 199

Query: 114 QMDGGSRPPAELDGQMDGGSRPPAELDGQMDGGSRPPAELDGQMDTGSRPPAELDGQMDT 173
           QM        E + QM        E + QM        E + Q+        + + QM  
Sbjct: 200 QMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRK 259

Query: 174 GSRPPAELDGQMDTGSRPPAELDGQTDTGSRPPAELDGQMDRGSRPPAELDGQM 227
                 E + QM        +   QT+       E + QM        E + QM
Sbjct: 260 QEEQMREQEEQMREQEEQMLKQKEQTEQ-EEQTGEQEEQMREQEEQMREQEEQM 312


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.135    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,091,028
Number of Sequences: 37866
Number of extensions: 1158694
Number of successful extensions: 4480
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 242
Number of HSP's that attempted gapping in prelim test: 3310
Number of HSP's gapped (non-prelim): 889
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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