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Search of human proteins with 117320527
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117320527 nuclear factor of kappa light polypeptide gene
enhancer in B-cells 2 isoform b [Homo sapiens]
(899 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117320540 nuclear factor of kappa light polypeptide gene enha... 1811 0.0
gi|117320527 nuclear factor of kappa light polypeptide gene enha... 1811 0.0
gi|117320531 nuclear factor of kappa light polypeptide gene enha... 1806 0.0
gi|34577122 nuclear factor kappa-B, subunit 1 [Homo sapiens] 657 0.0
gi|4506473 v-rel reticuloendotheliosis viral oncogene homolog [H... 249 8e-66
gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog ... 248 2e-65
gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog ... 246 9e-65
gi|35493878 reticuloendotheliosis viral oncogene homolog B [Homo... 221 2e-57
gi|164664508 B-cell CLL/lymphoma 3 [Homo sapiens] 149 9e-36
gi|71274109 nuclear factor of kappa light polypeptide gene enhan... 135 2e-31
gi|21361135 nuclear factor of kappa light polypeptide gene enhan... 119 1e-26
gi|10092619 nuclear factor of kappa light polypeptide gene enhan... 114 3e-25
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] 112 1e-24
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 112 1e-24
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 112 1e-24
gi|48928017 nuclear factor of kappa light polypeptide gene enhan... 102 2e-21
gi|41281709 nuclear factor of kappa light polypeptide gene enhan... 101 3e-21
gi|53832024 nuclear factor of kappa light polypeptide gene enhan... 101 4e-21
gi|13899229 nuclear factor of kappa light polypeptide gene enhan... 101 4e-21
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 97 9e-20
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 93 1e-18
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 91 5e-18
gi|30348954 mindbomb homolog 1 [Homo sapiens] 91 6e-18
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens] 90 8e-18
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] 90 8e-18
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] 90 8e-18
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] 90 8e-18
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens] 90 8e-18
gi|30425444 ankyrin repeat and kinase domain containing 1 [Homo ... 90 1e-17
gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo ... 87 7e-17
>gi|117320540 nuclear factor of kappa light polypeptide gene
enhancer in B-cells 2 isoform b [Homo sapiens]
Length = 899
Score = 1811 bits (4690), Expect = 0.0
Identities = 899/899 (100%), Positives = 899/899 (100%)
Query: 1 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP 60
MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
Sbjct: 1 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP 60
Query: 61 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC 120
SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
Sbjct: 61 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC 120
Query: 121 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE 180
AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
Sbjct: 121 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE 180
Query: 181 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV 240
LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
Sbjct: 181 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV 240
Query: 241 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE 300
RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
Sbjct: 241 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE 300
Query: 301 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS 360
RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
Sbjct: 301 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS 360
Query: 361 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA 420
GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
Sbjct: 361 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA 420
Query: 421 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL 480
AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
Sbjct: 421 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL 480
Query: 481 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 540
LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
Sbjct: 481 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 540
Query: 541 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG 600
SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
Sbjct: 541 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG 600
Query: 601 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN 660
LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
Sbjct: 601 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN 660
Query: 661 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP 720
VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
Sbjct: 661 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP 720
Query: 721 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ 780
EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
Sbjct: 721 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ 780
Query: 781 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL 840
LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
Sbjct: 781 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL 840
Query: 841 EEGVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH 899
EEGVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
Sbjct: 841 EEGVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH 899
>gi|117320527 nuclear factor of kappa light polypeptide gene
enhancer in B-cells 2 isoform b [Homo sapiens]
Length = 899
Score = 1811 bits (4690), Expect = 0.0
Identities = 899/899 (100%), Positives = 899/899 (100%)
Query: 1 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP 60
MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
Sbjct: 1 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP 60
Query: 61 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC 120
SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
Sbjct: 61 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC 120
Query: 121 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE 180
AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
Sbjct: 121 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE 180
Query: 181 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV 240
LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
Sbjct: 181 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV 240
Query: 241 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE 300
RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
Sbjct: 241 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE 300
Query: 301 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS 360
RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
Sbjct: 301 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS 360
Query: 361 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA 420
GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
Sbjct: 361 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA 420
Query: 421 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL 480
AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
Sbjct: 421 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL 480
Query: 481 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 540
LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
Sbjct: 481 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 540
Query: 541 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG 600
SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
Sbjct: 541 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG 600
Query: 601 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN 660
LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
Sbjct: 601 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN 660
Query: 661 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP 720
VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
Sbjct: 661 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP 720
Query: 721 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ 780
EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
Sbjct: 721 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ 780
Query: 781 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL 840
LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
Sbjct: 781 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL 840
Query: 841 EEGVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH 899
EEGVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
Sbjct: 841 EEGVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH 899
>gi|117320531 nuclear factor of kappa light polypeptide gene
enhancer in B-cells 2 isoform a [Homo sapiens]
Length = 900
Score = 1806 bits (4678), Expect = 0.0
Identities = 899/900 (99%), Positives = 899/900 (99%), Gaps = 1/900 (0%)
Query: 1 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP 60
MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
Sbjct: 1 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP 60
Query: 61 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC 120
SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC
Sbjct: 61 SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC 120
Query: 121 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE 180
AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE
Sbjct: 121 AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE 180
Query: 181 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV 240
LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
Sbjct: 181 LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV 240
Query: 241 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE 300
RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
Sbjct: 241 RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE 300
Query: 301 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS 360
RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
Sbjct: 301 RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS 360
Query: 361 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA 420
GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA
Sbjct: 361 GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA 420
Query: 421 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL 480
AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL
Sbjct: 421 AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL 480
Query: 481 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 540
LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT
Sbjct: 481 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 540
Query: 541 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG 600
SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG
Sbjct: 541 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG 600
Query: 601 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN 660
LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN
Sbjct: 601 LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN 660
Query: 661 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP 720
VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP
Sbjct: 661 VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP 720
Query: 721 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ 780
EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ
Sbjct: 721 EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ 780
Query: 781 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL 840
LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL
Sbjct: 781 LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL 840
Query: 841 EEGVRLLRGPETRDKLPST-EVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH 899
EEGVRLLRGPETRDKLPST EVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH
Sbjct: 841 EEGVRLLRGPETRDKLPSTAEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH 900
>gi|34577122 nuclear factor kappa-B, subunit 1 [Homo sapiens]
Length = 969
Score = 657 bits (1695), Expect = 0.0
Identities = 395/892 (44%), Positives = 522/892 (58%), Gaps = 72/892 (8%)
Query: 21 NSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTV 80
N + +P+ P TADGPYL I+EQPKQRGFRFRY CEGPSHGGLPGASSEK +K+YP V
Sbjct: 27 NPEVFQPQMALP-TADGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQV 85
Query: 81 KICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNLGVLH 140
KICNY GPAK+ V LVT+ HAHSLVGK C + GIC V+ GPKDM F NLG+LH
Sbjct: 86 KICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCED-GICTVTAGPKDMVVGFANLGILH 144
Query: 141 VTKKNMMGTMIQKLQRQRLRSRPQGLT-------------------EAEQRELEQEAKEL 181
VTKK + T+ ++ +R GL + E+ + Q A +
Sbjct: 145 VTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQAEGGGDRQLGDREKELIRQAALQQ 204
Query: 182 KKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVR 241
K MDLS+VRL F+AFL S GSF+ L+PV+S I+DSK+P ASNLKI RMD+TAG V
Sbjct: 205 TKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVT 264
Query: 242 GGDEVYLLCDKVQKDDIEVRFYEDDENG--WQAFGDFSPTDVHKQYAIVFRTPPYHKMKI 299
GG+E+YLLCDKVQKDDI++RFYE++ENG W+ FGDFSPTDVH+Q+AIVF+TP Y + I
Sbjct: 265 GGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDINI 324
Query: 300 ERPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGG 359
+P +VF+QL+RK + S+ K F YYP ++DKEEVQRKR+K +P FS FGGGS G G
Sbjct: 325 TKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGSGAGAG 384
Query: 360 SGGAAGGYGGAGGGGSLG---FFP-------SSLAYSP--YQSGAG-------------P 394
GG G GG GG GS G FP + + P +S AG P
Sbjct: 385 GGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITFHPGTTKSNAGMKHGTMDTESKKDP 444
Query: 395 MGCYPGGGG------GAQMAATVPSRDSGEEAAEPSAPSRTPQCEPQAPEMLQRAREYNA 448
GC G + T ++ E + T + + +
Sbjct: 445 EGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNGEVTLTYATGTKEESAGVQDNLFLE 504
Query: 449 RLFGLAQRSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIV 508
+ LA+R A AL DY VT D + LLA QRHL QDENGD+ LHLAIIH + ++ ++
Sbjct: 505 KAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHSQLVRDLL 564
Query: 509 YVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLAL 568
V ++N+ N L+QTPLHLAVIT Q VV LLR GAD +LLDR G+S +HLA
Sbjct: 565 EVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLHLA- 623
Query: 569 RAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEA 628
A G ++L LL+ A+ LL P+ +GL +HLA+ + S CL LLV +GA+V A
Sbjct: 624 -AKEGHDKVLSILLKHKKAAL--LLDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNA 680
Query: 629 TERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLL 688
E++ GRTALHLA E + + L L+ + A+V++ T+ G TPLH+AAG G L LL
Sbjct: 681 QEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLK 740
Query: 689 KAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLN 748
AGAD EN EPL L D ++ G ++ G TPLD+ S +V +L
Sbjct: 741 AAGADPLVENFEPLYDL------DDSWENAGEDEGV---VPGTTPLDMATSWQVFDILNG 791
Query: 749 AAQNTMEPPLTPPSPAGPG--LSLGDTALQNLEQLLDGPEAQGSWAELAERLGLRSLVDT 806
EP T G L + L +LL+ P+ +WA LA++LGL L +
Sbjct: 792 ---KPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKLGLGILNNA 848
Query: 807 YRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGLEEGVRLLRGPETRDKLPS 858
+R + +PS +L+ +YE++GG + L+EAL MG E + +++ + K S
Sbjct: 849 FRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTS 900
>gi|4506473 v-rel reticuloendotheliosis viral oncogene homolog [Homo
sapiens]
Length = 619
Score = 249 bits (636), Expect = 8e-66
Identities = 136/314 (43%), Positives = 188/314 (59%), Gaps = 16/314 (5%)
Query: 35 ADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVD 94
A PY+ I+EQP+QRG RFRY CEG S G +PG S +TYP+++I NY G K+ +
Sbjct: 5 AYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPSIQIMNYYGKGKVRIT 64
Query: 95 LVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKL 154
LVT +DP + H H LVGK C + G G + F NLG+ V KK + +I ++
Sbjct: 65 LVTKNDPYKPHPHDLVGKDCRD-GYYEAEFGQERRPLFFQNLGIRCVKKKEVKEAIITRI 123
Query: 155 QRQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVIS 214
+ P + E + ++E DL++VRL F FL G+ + L PV+S
Sbjct: 124 ---KAGINPFNVPEKQLNDIED--------CDLNVVRLCFQVFLPDEHGNLTTALPPVVS 172
Query: 215 QPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFG 274
PI+D+++P + L+I R++K GSVRGGDE++LLCDKVQKDDIEVRF +D W+A G
Sbjct: 173 NPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLND---WEAKG 229
Query: 275 DFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEE 334
FS DVH+Q AIVF+TPPY K I PVTV +QL+R +VS+S F Y P +D
Sbjct: 230 IFSQADVHRQVAIVFKTPPYCK-AITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTYG 288
Query: 335 VQRKRRKALPTFSQ 348
+ K++K F +
Sbjct: 289 NKAKKQKTTLLFQK 302
>gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog A
isoform 1 [Homo sapiens]
Length = 551
Score = 248 bits (632), Expect = 2e-65
Identities = 137/334 (41%), Positives = 188/334 (56%), Gaps = 25/334 (7%)
Query: 24 IVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKIC 83
++ P EPA A GPY+ I+EQPKQRG RFRY CEG S G +PG S KT+PT+KI
Sbjct: 7 LIFPAEPAQ--ASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKIN 64
Query: 84 NYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNLGVLHVTK 143
Y GP + + LVT P R H H LVGK C + G + P F NLG+ V K
Sbjct: 65 GYTGPGTVRISLVTKDPPHRPHPHELVGKDCRD-GFYEAELCPDRCIHSFQNLGIQCVKK 123
Query: 144 KNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFSAFLRASDG 203
+++ + Q++Q + +E + DL+ VRL F +R G
Sbjct: 124 RDLEQAISQRIQ-------------TNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSG 170
Query: 204 SFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFY 263
L L PV+S PI D+++P + LKI R+++ +GS GGDE++LLCDKVQK+DIEV F
Sbjct: 171 R-PLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYF- 228
Query: 264 EDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQF 323
GW+A G FS DVH+Q AIVFRTPPY ++ PV V +QL+R ++S+ +F
Sbjct: 229 --TGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEF 286
Query: 324 TYYPLVEDKEEVQRKRRKALPTF-----SQPFGG 352
Y P +D+ ++ KR++ TF PF G
Sbjct: 287 QYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSG 320
>gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog A
isoform 2 [Homo sapiens]
Length = 548
Score = 246 bits (627), Expect = 9e-65
Identities = 139/334 (41%), Positives = 188/334 (56%), Gaps = 28/334 (8%)
Query: 24 IVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKIC 83
++ P EPA A GPY+ I+EQPKQRG RFRY CEG S G +PG S KT+PT+KI
Sbjct: 7 LIFPAEPAQ--ASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKIN 64
Query: 84 NYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQFNNLGVLHVTK 143
Y GP + + LVT P R H H LVGK C + G + P F NLG+ V K
Sbjct: 65 GYTGPGTVRISLVTKDPPHRPHPHELVGKDCRD-GFYEAELCPDRCIHSFQNLGIQCVKK 123
Query: 144 KNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFSAFLRASDG 203
+++ + Q++Q T + EQ DL+ VRL F +R G
Sbjct: 124 RDLEQAISQRIQ-----------TNNNPFQEEQRGD-----YDLNAVRLCFQVTVRDPSG 167
Query: 204 SFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFY 263
L L PV+S PI D+++P + LKI R+++ +GS GGDE++LLCDKVQK+DIEV F
Sbjct: 168 R-PLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYF- 225
Query: 264 EDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQF 323
GW+A G FS DVH+Q AIVFRTPPY ++ PV V +QL+R ++S+ +F
Sbjct: 226 --TGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEF 283
Query: 324 TYYPLVEDKEEVQRKRRKALPTF-----SQPFGG 352
Y P +D+ ++ KR++ TF PF G
Sbjct: 284 QYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSG 317
>gi|35493878 reticuloendotheliosis viral oncogene homolog B [Homo
sapiens]
Length = 579
Score = 221 bits (564), Expect = 2e-57
Identities = 131/318 (41%), Positives = 180/318 (56%), Gaps = 21/318 (6%)
Query: 30 PAPETADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKICNYEGPA 89
PAP P+LVI EQPKQRG RFRY CEG S G + G SS + KT P +++ + G
Sbjct: 117 PAPGPGPQPHLVITEQPKQRGMRFRYECEGRSAGSILGESSTEASKTLPAIELRDCGGLR 176
Query: 90 KIEVD--LVTHSDPPRAHAHSLVGKQCSELGICAVSVGPK-DMTAQFNNLGVLHVTKKNM 146
++EV LV P R H HSLVGK C++ GIC V + P FNNLG+ V KK +
Sbjct: 177 EVEVTACLVWKDWPHRVHPHSLVGKDCTD-GICRVRLRPHVSPRHSFNNLGIQCVRKKEI 235
Query: 147 MGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELKKVMDLSIVRLRFSAFLRASDGSFS 206
+ +K+Q G+ L+ + +D+++VR+ F A R G
Sbjct: 236 EAAIERKIQL--------GIDPYNAGSLKNHQE-----VDMNVVRICFQASYRDQQGQMR 282
Query: 207 LPLKPVISQPIHDSKSPGASNLKISRMDKTAGSVRGGDEVYLLCDKVQKDDIEVRFYEDD 266
+ PV+S+P++D KS S L+I R++K +G GG+E+YLLCDKVQK+DI V F
Sbjct: 283 R-MDPVLSEPVYDKKSTNTSELRICRINKESGPCTGGEELYLLCDKVQKEDISVVF---S 338
Query: 267 ENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYY 326
W+ DFS DVH+Q AIVF+TPPY ++I PVTV + L+R G S+ FTY
Sbjct: 339 RASWEGRADFSQADVHRQIAIVFKTPPYEDLEIVEPVTVNVFLQRLTDGVCSEPLPFTYL 398
Query: 327 PLVEDKEEVQRKRRKALP 344
P D V +KR++ +P
Sbjct: 399 PRDHDSYGVDKKRKRGMP 416
>gi|164664508 B-cell CLL/lymphoma 3 [Homo sapiens]
Length = 454
Score = 149 bits (377), Expect = 9e-36
Identities = 108/313 (34%), Positives = 158/313 (50%), Gaps = 47/313 (15%)
Query: 480 LLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQ 539
+ T DE+GDTPLH+A++ G + ++V + Q +++ N+L QTPLHLAVIT
Sbjct: 127 MATRADEDGDTPLHIAVVQGNLPAVHRLVNLFQ--QGGRELDIYNNLRQTPLHLAVITTL 184
Query: 540 TSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFE 599
SVV L+ GA P LDRHG +A HLA +P LRALL S AP L +++
Sbjct: 185 PSVVRLLVTAGASPMALDRHGQTAAHLACE--HRSPTCLRALLDSAAPGTLD-LEARNYD 241
Query: 600 GLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRA 659
GL +H+AV E + LL++ GA+++A + + GR+ L A E L +V L+ + A
Sbjct: 242 GLTALHVAVNTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMV-QLLLQHGA 300
Query: 660 NVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADI---HAENEEPLCPLPS--------- 707
NVNA+ ++G++ LH A+G G L R L+++GAD + N+ PL S
Sbjct: 301 NVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVARSRRVIDILRG 360
Query: 708 ----------PPTSDSDSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQN---TM 754
P S S + PE +R S G LL+A+ + +
Sbjct: 361 KATRPASTSQPDPSPDRSANTSPESSSRLSSNG---------------LLSASPSSSPSQ 405
Query: 755 EPPLTPPS-PAGP 766
PP PP P P
Sbjct: 406 SPPRDPPGFPMAP 418
>gi|71274109 nuclear factor of kappa light polypeptide gene enhancer
in B-cells inhibitor, epsilon [Homo sapiens]
Length = 500
Score = 135 bits (339), Expect = 2e-31
Identities = 111/338 (32%), Positives = 161/338 (47%), Gaps = 24/338 (7%)
Query: 380 PSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEAAEPSAPSRTPQCEPQAPEM 439
P S Y SG + A+ PS S + P P + PQ + A
Sbjct: 147 PDEAEESQYDSGIESLRSLRSLPESTSAPASGPSDGSPQPCTHPPGPVKEPQEKEDADG- 205
Query: 440 LQRAREYNARLFGLAQRSARALLDYGVTAD----------ARALLAGQRHLLTAQDENGD 489
E +G + + L G A+ AL Q LT E+GD
Sbjct: 206 -----ERADSTYGSSSLTYTLSLLGGPEAEDPAPRLPLPHVGALSPQQLEALTYISEDGD 260
Query: 490 TPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRV 549
T +HLA+IH +V+ + ++ V+++ N+L+QT LHLAV Q V L+
Sbjct: 261 TLVHLAVIHEAPAVLLCCLALLPQE----VLDIQNNLYQTALHLAVHLDQPGAVRALVLK 316
Query: 550 GADPALLDRHGDSAMHLALRAG--AGAPELLRALLQSGAPAVPQL-LHMPDFEGLYPVHL 606
GA AL DRHGD+A+H+A + A A LL + G L L + +++GL +H+
Sbjct: 317 GASRALQDRHGDTALHVACQRQHLACARCLLEGRPEPGRGTSHSLDLQLQNWQGLACLHI 376
Query: 607 AVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTF 666
A ++ ++LL+ +GA+++ E G+TALHLA E +E GLV L+ + A V+AR
Sbjct: 377 ATLQKNQPLMELLLRNGADIDVQEGTSGKTALHLAVETQERGLVQFLL-QAGAQVDARML 435
Query: 667 AGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCP 704
G TPLHLAAG G ++ L KAGAD N E P
Sbjct: 436 NGCTPLHLAAGRGLMGISSTLCKAGADSLLRNVEDETP 473
>gi|21361135 nuclear factor of kappa light polypeptide gene enhancer
in B-cells inhibitor, beta isoform a [Homo sapiens]
Length = 356
Score = 119 bits (298), Expect = 1e-26
Identities = 102/300 (34%), Positives = 136/300 (45%), Gaps = 52/300 (17%)
Query: 486 ENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSF 545
E+GDT LHLA+IH ++ +++ + ++L N L QT LHLA I G+TS V
Sbjct: 56 EDGDTALHLAVIHQHEPFLD---FLLGFSAGTEYMDLQNDLGQTALHLAAILGETSTVEK 112
Query: 546 LLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQ---------------SGAPAVP 590
L GA + +R G +A+HLA R GA A RALLQ G P
Sbjct: 113 LYAAGAGLCVAERRGHTALHLACRVGAHA--CARALLQPRPRRPREAPDTYLAQGPDRTP 170
Query: 591 QLLHMP---------------------------DFEGLYPVHLAVRARSPECLDLLVDSG 623
H P ++EG P+H+AV + E + LL D+G
Sbjct: 171 DTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDAG 230
Query: 624 AEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTL 683
A+++ E GR+ LHLA E + V L+ + AN AR + G TPL A P L
Sbjct: 231 ADLDKPEPTCGRSPLHLAVEAQAAD-VLELLLRAGANPAARMYGGRTPLGSAMLRPNPIL 289
Query: 684 TRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKD--TRSSFRGHTPLDLTCSTK 741
RLL GA +E P S +SDSDS EG E D S R T L T ++K
Sbjct: 290 ARLLRAHGAPEPEGEDEKSGPCSS--SSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASK 347
Score = 45.4 bits (106), Expect = 2e-04
Identities = 37/107 (34%), Positives = 51/107 (47%), Gaps = 7/107 (6%)
Query: 481 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 540
L A++ G TPLH+A+IH +E + + DL T ++PLHLAV
Sbjct: 200 LEAENYEGHTPLHVAVIHKD---VEMVRLLRDAGADLDKPEPT--CGRSPLHLAVEAQAA 254
Query: 541 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAP 587
V+ LLR GA+PA G + + A+ P L R L GAP
Sbjct: 255 DVLELLLRAGANPAARMYGGRTPLGSAML--RPNPILARLLRAHGAP 299
>gi|10092619 nuclear factor of kappa light polypeptide gene enhancer
in B-cells inhibitor, alpha [Homo sapiens]
Length = 317
Score = 114 bits (286), Expect = 3e-25
Identities = 92/252 (36%), Positives = 132/252 (52%), Gaps = 21/252 (8%)
Query: 486 ENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSF 545
E+GD+ LHLAIIH + ++ +++ + DL +N N+L QTPLHLAVIT Q +
Sbjct: 72 EDGDSFLHLAIIHEEKALTMEVIRQVKG--DLAFLNFQNNLQQTPLHLAVITNQPEIAEA 129
Query: 546 LLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQS-GAPAVPQLLHMPDFEGLYPV 604
LL G DP L D G++ +HLA G A + L QS P + +L ++ G +
Sbjct: 130 LLGAGCDPELRDFRGNTPLHLACEQGCLAS--VGVLTQSCTTPHLHSILKATNYNGHTCL 187
Query: 605 HLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR 664
HLA ++LLV GA+V A E GRTALHLA +++ LV+ L+ K A+VN
Sbjct: 188 HLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVS-LLLKCGADVNRV 246
Query: 665 TFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDT 724
T+ G +P L G P+ TR+ + G + EN + L P + D +S DT
Sbjct: 247 TYQGYSPYQLT--WGRPS-TRIQQQLG-QLTLENLQML-----PESEDEES------YDT 291
Query: 725 RSSFRGHTPLDL 736
S F T +L
Sbjct: 292 ESEFTEFTEDEL 303
Score = 44.3 bits (103), Expect = 5e-04
Identities = 40/120 (33%), Positives = 54/120 (45%), Gaps = 10/120 (8%)
Query: 480 LLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQ 539
+L A + NG T LHLA IHG ++E +V + D+ N +T LHLAV
Sbjct: 175 ILKATNYNGHTCLHLASIHGYLGIVELLVSL---GADVNAQEPCN--GRTALHLAVDLQN 229
Query: 540 TSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFE 599
+VS LL+ GAD + G S L G P R Q G + L +P+ E
Sbjct: 230 PDLVSLLLKCGADVNRVTYQGYSPYQLTW----GRPS-TRIQQQLGQLTLENLQMLPESE 284
>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
Length = 1863
Score = 112 bits (281), Expect = 1e-24
Identities = 121/445 (27%), Positives = 195/445 (43%), Gaps = 63/445 (14%)
Query: 459 RALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLG 518
R LL G DARA TPLH+A G+T +++ ++ + H D
Sbjct: 460 RCLLRNGALVDARA-------------REEQTPLHIASRLGKTEIVQLLLQHMAHP-DAA 505
Query: 519 VVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELL 578
N TPLH++ GQ V S LL GA +L + G + +H+A A G+ ++
Sbjct: 506 TTN-----GYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVA--AKYGSLDVA 558
Query: 579 RALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTAL 638
+ LLQ A A GL P+H+A + + LL++ GA AT + G T L
Sbjct: 559 KLLLQRRAAA-----DSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNG-YTPL 612
Query: 639 HLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAEN 698
H+A + ++ + + L+ A N T G TPLHLA+ G+ + LLL GA+IH
Sbjct: 613 HIAAKKNQMQIASTLLN-YGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST 671
Query: 699 EEPLCPLPSPPTSDSDSDSE-----GPEKDTRSSFRGHTPLDLTC---STKVKTLLLNAA 750
+ L L D + ++ G ++D + G+TPL + C + K+ LL
Sbjct: 672 KSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKL-GYTPLIVACHYGNVKMVNFLLKQG 730
Query: 751 QNTMEPPLTPPSPAGPGLSLGDTALQNLEQLLDGPEAQGSWAE------LAERLGLRSLV 804
N +P G T + N+ L G + + A +A+RLG S+V
Sbjct: 731 ANVNAKTKNGYTPLHQAAQQGHTHIINV-LLQHGAKPNATTANGNTALAIAKRLGYISVV 789
Query: 805 DTYR----QTTSPSGSLLRSYELAGGDLAGLLEALSDMGLEEGVRLLRG-------PET- 852
DT + + T+ + ++ ++L ++ + + D+ EEG + G PE
Sbjct: 790 DTLKVVTEEVTTTTTTITEKHKL---NVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDL 846
Query: 853 ----RDKLPSTEVKEDSAYGSQSVE 873
D LPS++ + Y S+E
Sbjct: 847 KELGDDSLPSSQFLDGMNYLRYSLE 871
Score = 92.8 bits (229), Expect = 1e-18
Identities = 79/250 (31%), Positives = 117/250 (46%), Gaps = 20/250 (8%)
Query: 456 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 515
+SA LL AD ++ + ++ E+G TPLH+A +G +V ++
Sbjct: 185 KSAALLLQNDHNADVQSKM-----MVNRTTESGFTPLHIAAHYGNVNVATLLL------N 233
Query: 516 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 575
V+ T TPLH+A G T++V LL G R G + +H A R+G
Sbjct: 234 RGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHD-- 291
Query: 576 ELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGR 635
+++ LL+ GAP + + + GL P+H+A + EC+ L+ A V+
Sbjct: 292 QVVELLLERGAPLLARTKN-----GLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDY-L 345
Query: 636 TALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIH 695
TALH+A VT L+ RAN NAR G TPLH+A + LL+K GA I
Sbjct: 346 TALHVAAHCGHYR-VTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQ 404
Query: 696 AENEEPLCPL 705
A E L P+
Sbjct: 405 AITESGLTPI 414
Score = 91.3 bits (225), Expect = 4e-18
Identities = 99/355 (27%), Positives = 158/355 (44%), Gaps = 41/355 (11%)
Query: 456 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 515
R + LLD +ARAL NG TPLH+A + V+E +V Q
Sbjct: 358 RVTKLLLDKRANPNARAL-------------NGFTPLHIACKKNRIKVMELLVKYGASIQ 404
Query: 516 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 575
+ LT P+H+A G ++V LL+ GA P + + G++A+H+A R AG
Sbjct: 405 AITESGLT------PIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAAR--AGQV 456
Query: 576 ELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGR 635
E++R LL++GA L+ E P+H+A R E + LL+ A +A G
Sbjct: 457 EVVRCLLRNGA-----LVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAA-TTNGY 510
Query: 636 TALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIH 695
T LH++ ++ + + L+ A+ + T G TPLH+AA G + +LLL+ A
Sbjct: 511 TPLHISAREGQVDVASVLLEAGAAH-SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAAD 569
Query: 696 AENEEPLCPLPSPPTSDSDSDS----EGPEKDTRSSFRGHTPLDLTC---STKVKTLLLN 748
+ + L PL D+ + E ++ G+TPL + ++ + LLN
Sbjct: 570 SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLN 629
Query: 749 AAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQLLDGPEAQGSWAELAERLGLRSL 803
T +P G T + L LLD +G+ ++ + GL SL
Sbjct: 630 YGAETNIVTKQGVTPLHLASQEGHTDMVTL--LLD----KGANIHMSTKSGLTSL 678
Score = 69.7 bits (169), Expect = 1e-11
Identities = 64/248 (25%), Positives = 112/248 (45%), Gaps = 25/248 (10%)
Query: 474 LAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHL 533
L G+ + + + G+T LH+A + GQ V++ +V ++ +N + TPL++
Sbjct: 62 LLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLV------KEGANINAQSQNGFTPLYM 115
Query: 534 AVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLL 593
A VV +LL GA+ + G + + +AL+ G + + LL++ +L
Sbjct: 116 AAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHN--QAVAILLENDTKGKVRLP 173
Query: 594 HMPDFEGLYPVHLAVRARSPECLDLLV--DSGAEVEAT-----ERQGGRTALHLATEMEE 646
+ H+A R + LL+ D A+V++ + G T LH+A
Sbjct: 174 AL---------HIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGN 224
Query: 647 LGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLP 706
+ + T L+ + A V+ G TPLH+A+ G + +LLL G I A+ + L PL
Sbjct: 225 VNVATLLLNR-GAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLH 283
Query: 707 SPPTSDSD 714
S D
Sbjct: 284 CAARSGHD 291
Score = 52.4 bits (124), Expect = 2e-06
Identities = 35/101 (34%), Positives = 59/101 (58%), Gaps = 5/101 (4%)
Query: 608 VRARSPECLDLLVD---SGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR 664
+RA LD +V+ G ++ T Q G ALHLA + +GLV L+ + ++V++
Sbjct: 15 LRAARAGNLDKVVEYLKGGIDIN-TCNQNGLNALHLAAKEGHVGLVQELLGR-GSSVDSA 72
Query: 665 TFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
T GNT LH+A+ G + ++L+K GA+I+A+++ PL
Sbjct: 73 TKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPL 113
Score = 51.2 bits (121), Expect = 4e-06
Identities = 64/241 (26%), Positives = 105/241 (43%), Gaps = 23/241 (9%)
Query: 534 AVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLL 593
A G V L+ G D +++G +A+HLA A G L++ LL G+ +
Sbjct: 17 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLA--AKEGHVGLVQELLGRGSS-----V 69
Query: 594 HMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHL 653
+G +H+A A E + +LV GA + A + Q G T L++A + + +V +L
Sbjct: 70 DSATKKGNTALHIASLAGQAEVVKVLVKEGANINA-QSQNGFTPLYMAAQENHIDVVKYL 128
Query: 654 VTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGAD-------IH-AENEEPLCPL 705
+ AN + T G TPL +A G+ +LL+ +H A ++
Sbjct: 129 LEN-GANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSA 187
Query: 706 PSPPTSDSDSDSEGPEKDTRSSFRGHTPLDLTC---STKVKTLLLN---AAQNTMEPPLT 759
+D ++D + R++ G TPL + + V TLLLN A T +T
Sbjct: 188 ALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGIT 247
Query: 760 P 760
P
Sbjct: 248 P 248
>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
Length = 1872
Score = 112 bits (281), Expect = 1e-24
Identities = 121/445 (27%), Positives = 195/445 (43%), Gaps = 63/445 (14%)
Query: 459 RALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLG 518
R LL G DARA TPLH+A G+T +++ ++ + H D
Sbjct: 481 RCLLRNGALVDARA-------------REEQTPLHIASRLGKTEIVQLLLQHMAHP-DAA 526
Query: 519 VVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELL 578
N TPLH++ GQ V S LL GA +L + G + +H+A A G+ ++
Sbjct: 527 TTN-----GYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVA--AKYGSLDVA 579
Query: 579 RALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTAL 638
+ LLQ A A GL P+H+A + + LL++ GA AT + G T L
Sbjct: 580 KLLLQRRAAA-----DSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNG-YTPL 633
Query: 639 HLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAEN 698
H+A + ++ + + L+ A N T G TPLHLA+ G+ + LLL GA+IH
Sbjct: 634 HIAAKKNQMQIASTLLN-YGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST 692
Query: 699 EEPLCPLPSPPTSDSDSDSE-----GPEKDTRSSFRGHTPLDLTC---STKVKTLLLNAA 750
+ L L D + ++ G ++D + G+TPL + C + K+ LL
Sbjct: 693 KSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKL-GYTPLIVACHYGNVKMVNFLLKQG 751
Query: 751 QNTMEPPLTPPSPAGPGLSLGDTALQNLEQLLDGPEAQGSWAE------LAERLGLRSLV 804
N +P G T + N+ L G + + A +A+RLG S+V
Sbjct: 752 ANVNAKTKNGYTPLHQAAQQGHTHIINV-LLQHGAKPNATTANGNTALAIAKRLGYISVV 810
Query: 805 DTYR----QTTSPSGSLLRSYELAGGDLAGLLEALSDMGLEEGVRLLRG-------PET- 852
DT + + T+ + ++ ++L ++ + + D+ EEG + G PE
Sbjct: 811 DTLKVVTEEVTTTTTTITEKHKL---NVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDL 867
Query: 853 ----RDKLPSTEVKEDSAYGSQSVE 873
D LPS++ + Y S+E
Sbjct: 868 KELGDDSLPSSQFLDGMNYLRYSLE 892
Score = 92.8 bits (229), Expect = 1e-18
Identities = 79/250 (31%), Positives = 117/250 (46%), Gaps = 20/250 (8%)
Query: 456 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 515
+SA LL AD ++ + ++ E+G TPLH+A +G +V ++
Sbjct: 206 KSAALLLQNDHNADVQSKM-----MVNRTTESGFTPLHIAAHYGNVNVATLLL------N 254
Query: 516 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 575
V+ T TPLH+A G T++V LL G R G + +H A R+G
Sbjct: 255 RGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHD-- 312
Query: 576 ELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGR 635
+++ LL+ GAP + + + GL P+H+A + EC+ L+ A V+
Sbjct: 313 QVVELLLERGAPLLARTKN-----GLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDY-L 366
Query: 636 TALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIH 695
TALH+A VT L+ RAN NAR G TPLH+A + LL+K GA I
Sbjct: 367 TALHVAAHCGHYR-VTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQ 425
Query: 696 AENEEPLCPL 705
A E L P+
Sbjct: 426 AITESGLTPI 435
Score = 91.3 bits (225), Expect = 4e-18
Identities = 99/355 (27%), Positives = 158/355 (44%), Gaps = 41/355 (11%)
Query: 456 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 515
R + LLD +ARAL NG TPLH+A + V+E +V Q
Sbjct: 379 RVTKLLLDKRANPNARAL-------------NGFTPLHIACKKNRIKVMELLVKYGASIQ 425
Query: 516 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 575
+ LT P+H+A G ++V LL+ GA P + + G++A+H+A R AG
Sbjct: 426 AITESGLT------PIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAAR--AGQV 477
Query: 576 ELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGR 635
E++R LL++GA L+ E P+H+A R E + LL+ A +A G
Sbjct: 478 EVVRCLLRNGA-----LVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAA-TTNGY 531
Query: 636 TALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIH 695
T LH++ ++ + + L+ A+ + T G TPLH+AA G + +LLL+ A
Sbjct: 532 TPLHISAREGQVDVASVLLEAGAAH-SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAAD 590
Query: 696 AENEEPLCPLPSPPTSDSDSDS----EGPEKDTRSSFRGHTPLDLTC---STKVKTLLLN 748
+ + L PL D+ + E ++ G+TPL + ++ + LLN
Sbjct: 591 SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLN 650
Query: 749 AAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQLLDGPEAQGSWAELAERLGLRSL 803
T +P G T + L LLD +G+ ++ + GL SL
Sbjct: 651 YGAETNIVTKQGVTPLHLASQEGHTDMVTL--LLD----KGANIHMSTKSGLTSL 699
Score = 69.7 bits (169), Expect = 1e-11
Identities = 64/248 (25%), Positives = 112/248 (45%), Gaps = 25/248 (10%)
Query: 474 LAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHL 533
L G+ + + + G+T LH+A + GQ V++ +V ++ +N + TPL++
Sbjct: 83 LLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLV------KEGANINAQSQNGFTPLYM 136
Query: 534 AVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLL 593
A VV +LL GA+ + G + + +AL+ G + + LL++ +L
Sbjct: 137 AAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHN--QAVAILLENDTKGKVRLP 194
Query: 594 HMPDFEGLYPVHLAVRARSPECLDLLV--DSGAEVEAT-----ERQGGRTALHLATEMEE 646
+ H+A R + LL+ D A+V++ + G T LH+A
Sbjct: 195 AL---------HIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGN 245
Query: 647 LGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLP 706
+ + T L+ + A V+ G TPLH+A+ G + +LLL G I A+ + L PL
Sbjct: 246 VNVATLLLNR-GAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLH 304
Query: 707 SPPTSDSD 714
S D
Sbjct: 305 CAARSGHD 312
Score = 52.4 bits (124), Expect = 2e-06
Identities = 35/101 (34%), Positives = 59/101 (58%), Gaps = 5/101 (4%)
Query: 608 VRARSPECLDLLVD---SGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR 664
+RA LD +V+ G ++ T Q G ALHLA + +GLV L+ + ++V++
Sbjct: 36 LRAARAGNLDKVVEYLKGGIDIN-TCNQNGLNALHLAAKEGHVGLVQELLGR-GSSVDSA 93
Query: 665 TFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
T GNT LH+A+ G + ++L+K GA+I+A+++ PL
Sbjct: 94 TKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPL 134
Score = 51.2 bits (121), Expect = 4e-06
Identities = 64/241 (26%), Positives = 105/241 (43%), Gaps = 23/241 (9%)
Query: 534 AVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLL 593
A G V L+ G D +++G +A+HLA A G L++ LL G+ +
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLA--AKEGHVGLVQELLGRGSS-----V 90
Query: 594 HMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHL 653
+G +H+A A E + +LV GA + A + Q G T L++A + + +V +L
Sbjct: 91 DSATKKGNTALHIASLAGQAEVVKVLVKEGANINA-QSQNGFTPLYMAAQENHIDVVKYL 149
Query: 654 VTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGAD-------IH-AENEEPLCPL 705
+ AN + T G TPL +A G+ +LL+ +H A ++
Sbjct: 150 LEN-GANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSA 208
Query: 706 PSPPTSDSDSDSEGPEKDTRSSFRGHTPLDLTC---STKVKTLLLN---AAQNTMEPPLT 759
+D ++D + R++ G TPL + + V TLLLN A T +T
Sbjct: 209 ALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGIT 268
Query: 760 P 760
P
Sbjct: 269 P 269
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 112 bits (281), Expect = 1e-24
Identities = 121/445 (27%), Positives = 195/445 (43%), Gaps = 63/445 (14%)
Query: 459 RALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLG 518
R LL G DARA TPLH+A G+T +++ ++ + H D
Sbjct: 481 RCLLRNGALVDARA-------------REEQTPLHIASRLGKTEIVQLLLQHMAHP-DAA 526
Query: 519 VVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELL 578
N TPLH++ GQ V S LL GA +L + G + +H+A A G+ ++
Sbjct: 527 TTN-----GYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVA--AKYGSLDVA 579
Query: 579 RALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTAL 638
+ LLQ A A GL P+H+A + + LL++ GA AT + G T L
Sbjct: 580 KLLLQRRAAA-----DSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNG-YTPL 633
Query: 639 HLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAEN 698
H+A + ++ + + L+ A N T G TPLHLA+ G+ + LLL GA+IH
Sbjct: 634 HIAAKKNQMQIASTLLN-YGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMST 692
Query: 699 EEPLCPLPSPPTSDSDSDSE-----GPEKDTRSSFRGHTPLDLTC---STKVKTLLLNAA 750
+ L L D + ++ G ++D + G+TPL + C + K+ LL
Sbjct: 693 KSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKL-GYTPLIVACHYGNVKMVNFLLKQG 751
Query: 751 QNTMEPPLTPPSPAGPGLSLGDTALQNLEQLLDGPEAQGSWAE------LAERLGLRSLV 804
N +P G T + N+ L G + + A +A+RLG S+V
Sbjct: 752 ANVNAKTKNGYTPLHQAAQQGHTHIINV-LLQHGAKPNATTANGNTALAIAKRLGYISVV 810
Query: 805 DTYR----QTTSPSGSLLRSYELAGGDLAGLLEALSDMGLEEGVRLLRG-------PET- 852
DT + + T+ + ++ ++L ++ + + D+ EEG + G PE
Sbjct: 811 DTLKVVTEEVTTTTTTITEKHKL---NVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDL 867
Query: 853 ----RDKLPSTEVKEDSAYGSQSVE 873
D LPS++ + Y S+E
Sbjct: 868 KELGDDSLPSSQFLDGMNYLRYSLE 892
Score = 92.8 bits (229), Expect = 1e-18
Identities = 79/250 (31%), Positives = 117/250 (46%), Gaps = 20/250 (8%)
Query: 456 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 515
+SA LL AD ++ + ++ E+G TPLH+A +G +V ++
Sbjct: 206 KSAALLLQNDHNADVQSKM-----MVNRTTESGFTPLHIAAHYGNVNVATLLL------N 254
Query: 516 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 575
V+ T TPLH+A G T++V LL G R G + +H A R+G
Sbjct: 255 RGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHD-- 312
Query: 576 ELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGR 635
+++ LL+ GAP + + + GL P+H+A + EC+ L+ A V+
Sbjct: 313 QVVELLLERGAPLLARTKN-----GLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDY-L 366
Query: 636 TALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIH 695
TALH+A VT L+ RAN NAR G TPLH+A + LL+K GA I
Sbjct: 367 TALHVAAHCGHYR-VTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQ 425
Query: 696 AENEEPLCPL 705
A E L P+
Sbjct: 426 AITESGLTPI 435
Score = 91.3 bits (225), Expect = 4e-18
Identities = 99/355 (27%), Positives = 158/355 (44%), Gaps = 41/355 (11%)
Query: 456 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 515
R + LLD +ARAL NG TPLH+A + V+E +V Q
Sbjct: 379 RVTKLLLDKRANPNARAL-------------NGFTPLHIACKKNRIKVMELLVKYGASIQ 425
Query: 516 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 575
+ LT P+H+A G ++V LL+ GA P + + G++A+H+A R AG
Sbjct: 426 AITESGLT------PIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAAR--AGQV 477
Query: 576 ELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGR 635
E++R LL++GA L+ E P+H+A R E + LL+ A +A G
Sbjct: 478 EVVRCLLRNGA-----LVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAA-TTNGY 531
Query: 636 TALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIH 695
T LH++ ++ + + L+ A+ + T G TPLH+AA G + +LLL+ A
Sbjct: 532 TPLHISAREGQVDVASVLLEAGAAH-SLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAAD 590
Query: 696 AENEEPLCPLPSPPTSDSDSDS----EGPEKDTRSSFRGHTPLDLTC---STKVKTLLLN 748
+ + L PL D+ + E ++ G+TPL + ++ + LLN
Sbjct: 591 SAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLN 650
Query: 749 AAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQLLDGPEAQGSWAELAERLGLRSL 803
T +P G T + L LLD +G+ ++ + GL SL
Sbjct: 651 YGAETNIVTKQGVTPLHLASQEGHTDMVTL--LLD----KGANIHMSTKSGLTSL 699
Score = 69.7 bits (169), Expect = 1e-11
Identities = 64/248 (25%), Positives = 112/248 (45%), Gaps = 25/248 (10%)
Query: 474 LAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHL 533
L G+ + + + G+T LH+A + GQ V++ +V ++ +N + TPL++
Sbjct: 83 LLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLV------KEGANINAQSQNGFTPLYM 136
Query: 534 AVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLL 593
A VV +LL GA+ + G + + +AL+ G + + LL++ +L
Sbjct: 137 AAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHN--QAVAILLENDTKGKVRLP 194
Query: 594 HMPDFEGLYPVHLAVRARSPECLDLLV--DSGAEVEAT-----ERQGGRTALHLATEMEE 646
+ H+A R + LL+ D A+V++ + G T LH+A
Sbjct: 195 AL---------HIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGN 245
Query: 647 LGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLP 706
+ + T L+ + A V+ G TPLH+A+ G + +LLL G I A+ + L PL
Sbjct: 246 VNVATLLLNR-GAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLH 304
Query: 707 SPPTSDSD 714
S D
Sbjct: 305 CAARSGHD 312
Score = 52.4 bits (124), Expect = 2e-06
Identities = 35/101 (34%), Positives = 59/101 (58%), Gaps = 5/101 (4%)
Query: 608 VRARSPECLDLLVD---SGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR 664
+RA LD +V+ G ++ T Q G ALHLA + +GLV L+ + ++V++
Sbjct: 36 LRAARAGNLDKVVEYLKGGIDIN-TCNQNGLNALHLAAKEGHVGLVQELLGR-GSSVDSA 93
Query: 665 TFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
T GNT LH+A+ G + ++L+K GA+I+A+++ PL
Sbjct: 94 TKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPL 134
Score = 51.2 bits (121), Expect = 4e-06
Identities = 64/241 (26%), Positives = 105/241 (43%), Gaps = 23/241 (9%)
Query: 534 AVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLL 593
A G V L+ G D +++G +A+HLA A G L++ LL G+ +
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLA--AKEGHVGLVQELLGRGSS-----V 90
Query: 594 HMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHL 653
+G +H+A A E + +LV GA + A + Q G T L++A + + +V +L
Sbjct: 91 DSATKKGNTALHIASLAGQAEVVKVLVKEGANINA-QSQNGFTPLYMAAQENHIDVVKYL 149
Query: 654 VTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGAD-------IH-AENEEPLCPL 705
+ AN + T G TPL +A G+ +LL+ +H A ++
Sbjct: 150 LEN-GANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSA 208
Query: 706 PSPPTSDSDSDSEGPEKDTRSSFRGHTPLDLTC---STKVKTLLLN---AAQNTMEPPLT 759
+D ++D + R++ G TPL + + V TLLLN A T +T
Sbjct: 209 ALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGIT 268
Query: 760 P 760
P
Sbjct: 269 P 269
>gi|48928017 nuclear factor of kappa light polypeptide gene enhancer
in B-cells inhibitor, beta isoform b [Homo sapiens]
Length = 306
Score = 102 bits (253), Expect = 2e-21
Identities = 85/248 (34%), Positives = 111/248 (44%), Gaps = 47/248 (18%)
Query: 520 VNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLR 579
++L N L QT LHLA I G+TS V L GA + +R G +A+HLA R GA A R
Sbjct: 55 MDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHA--CAR 112
Query: 580 ALLQ---------------SGAPAVPQLLHMP---------------------------D 597
ALLQ G P H P +
Sbjct: 113 ALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAEN 172
Query: 598 FEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKL 657
+EG P+H+AV + E + LL D+GA+++ E GR+ LHLA E + V L+ +
Sbjct: 173 YEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAAD-VLELLLRA 231
Query: 658 RANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDS 717
AN AR + G TPL A P L RLL GA +E P S +SDSDS
Sbjct: 232 GANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSS--SSDSDSGD 289
Query: 718 EGPEKDTR 725
EG ++ R
Sbjct: 290 EGVSQEER 297
Score = 45.4 bits (106), Expect = 2e-04
Identities = 37/107 (34%), Positives = 51/107 (47%), Gaps = 7/107 (6%)
Query: 481 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 540
L A++ G TPLH+A+IH +E + + DL T ++PLHLAV
Sbjct: 168 LEAENYEGHTPLHVAVIHKD---VEMVRLLRDAGADLDKPEPT--CGRSPLHLAVEAQAA 222
Query: 541 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAP 587
V+ LLR GA+PA G + + A+ P L R L GAP
Sbjct: 223 DVLELLLRAGANPAARMYGGRTPLGSAML--RPNPILARLLRAHGAP 267
Score = 39.7 bits (91), Expect = 0.013
Identities = 76/286 (26%), Positives = 105/286 (36%), Gaps = 59/286 (20%)
Query: 622 SGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYP 681
+G E + G+TALHLA + E V L A + G+T LHLA +G
Sbjct: 50 AGTEYMDLQNDLGQTALHLAAILGETSTVEKLYA-AGAGLCVAERRGHTALHLACRVGAH 108
Query: 682 TLTRLLLK---------------AGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDTR- 725
R LL+ G D + P+ P SD + + E E+D +
Sbjct: 109 ACARALLQPRPRRPREAPDTYLAQGPDRTPDTNH--TPVALYPDSDLEKEEEESEEDWKL 166
Query: 726 ----SSFRGHTPLDLTC---STKVKTLLLNAAQNTMEP-PLTPPSPAGPGLSLGDTALQN 777
++ GHTPL + ++ LL +A + +P P SP L++ A
Sbjct: 167 QLEAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPL--HLAVEAQAADV 224
Query: 778 LEQLLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSD 837
LE LL R G Y T ++LR + LA LL A
Sbjct: 225 LELLL--------------RAGANPAARMYGGRTPLGSAMLRPNPI----LARLLRA--- 263
Query: 838 MGLEEGVRLLRGPETRD-KLPSTEVKEDSAYGSQSVEQEAEKLGPP 882
G E PE D K DS G + V QE E+ G P
Sbjct: 264 HGAPE-------PEGEDEKSGPCSSSSDSDSGDEGVSQE-ERQGSP 301
>gi|41281709 nuclear factor of kappa light polypeptide gene enhancer
in B-cells inhibitor, delta [Homo sapiens]
Length = 313
Score = 101 bits (252), Expect = 3e-21
Identities = 95/276 (34%), Positives = 127/276 (46%), Gaps = 46/276 (16%)
Query: 468 ADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLH 527
A A L G + LL AQDE GDT LHL G V+ + L ++ H
Sbjct: 30 ARAHMLALGPQQLL-AQDEEGDTLLHLFAARGLRWAAYAAAEVLQVYRRL---DIREHKG 85
Query: 528 QTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAP 587
+TPL +A Q +V LL +GA+P D G S +H+A A G P +L A+L SG
Sbjct: 86 KTPLLVAAAANQPLIVEDLLNLGAEPNAADHQGRSVLHVA--ATYGLPGVLLAVLNSG-- 141
Query: 588 AVPQLLHMPDFEGLYPVHLAVRARSP--------------------ECLDLLVDSGAEVE 627
V L DFEGL P+H A+ A + +C+ +L+ GA
Sbjct: 142 -VQVDLEARDFEGLTPLHTAILALNVAMRPSDLCPRVLSTQARDRLDCVHMLLQMGANHT 200
Query: 628 ATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFA-----GNTPLHLAAGL---- 678
+ E + +T LHLA + LV L+ R ++ RTF GNT LH+AA L
Sbjct: 201 SQEIKSNKTVLHLAVQAANPTLVQLLLELPRGDL--RTFVNMKAHGNTALHMAAALPPGP 258
Query: 679 GYPTLTRLLLKAGAD---IHAENEEP---LCPLPSP 708
+ R LL AGAD + ENE+P L P P P
Sbjct: 259 AQEAIVRHLLAAGADPTLRNLENEQPVHLLRPGPGP 294
>gi|53832024 nuclear factor of kappa light polypeptide gene enhancer
in B-cells inhibitor, zeta isoform b [Homo sapiens]
Length = 618
Score = 101 bits (251), Expect = 4e-21
Identities = 88/293 (30%), Positives = 140/293 (47%), Gaps = 46/293 (15%)
Query: 459 RALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQD-L 517
++L + V + L + ++D +GDT LH+A+ G+ + + YV+ + L
Sbjct: 315 KSLFQWQVEQEESKLANISQDQFLSKDADGDTFLHIAVAQGRRA----LSYVLARKMNAL 370
Query: 518 GVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPEL 577
++++ H Q+ +AV Q +V L+ +GA D G + +H+ A G ++
Sbjct: 371 HMLDIKEHNGQSAFQVAVAANQHLIVQDLVNIGAQVNTTDCWGRTPLHVC--AEKGHSQV 428
Query: 578 LRALLQSGAPAVPQL--LHMPDFEGLYPVHLAVRAR--------------SPECLDLL-- 619
L+A+ Q GA Q L +++GL P+H AV A SPE +LL
Sbjct: 429 LQAI-QKGAVGSNQFVDLEATNYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLK 487
Query: 620 -----------VDSGAEVEATERQGGRTALHLATEMEELGLVTHL--VTKLRANVNARTF 666
+ GA VEA +R+ GRTALHLA E L L+ + + VNA+ +
Sbjct: 488 NKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAY 547
Query: 667 AGNTPLHLAAGLGYP----TLTRLLLKAGAD---IHAENEEPLCPLPSPPTSD 712
GNT LH+AA L Y RLL++ GAD + ENE+P+ +P P +
Sbjct: 548 NGNTALHVAASLQYRLTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGE 600
>gi|13899229 nuclear factor of kappa light polypeptide gene enhancer
in B-cells inhibitor, zeta isoform a [Homo sapiens]
Length = 718
Score = 101 bits (251), Expect = 4e-21
Identities = 88/293 (30%), Positives = 140/293 (47%), Gaps = 46/293 (15%)
Query: 459 RALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQD-L 517
++L + V + L + ++D +GDT LH+A+ G+ + + YV+ + L
Sbjct: 415 KSLFQWQVEQEESKLANISQDQFLSKDADGDTFLHIAVAQGRRA----LSYVLARKMNAL 470
Query: 518 GVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPEL 577
++++ H Q+ +AV Q +V L+ +GA D G + +H+ A G ++
Sbjct: 471 HMLDIKEHNGQSAFQVAVAANQHLIVQDLVNIGAQVNTTDCWGRTPLHVC--AEKGHSQV 528
Query: 578 LRALLQSGAPAVPQL--LHMPDFEGLYPVHLAVRAR--------------SPECLDLL-- 619
L+A+ Q GA Q L +++GL P+H AV A SPE +LL
Sbjct: 529 LQAI-QKGAVGSNQFVDLEATNYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLK 587
Query: 620 -----------VDSGAEVEATERQGGRTALHLATEMEELGLVTHL--VTKLRANVNARTF 666
+ GA VEA +R+ GRTALHLA E L L+ + + VNA+ +
Sbjct: 588 NKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAY 647
Query: 667 AGNTPLHLAAGLGYP----TLTRLLLKAGAD---IHAENEEPLCPLPSPPTSD 712
GNT LH+AA L Y RLL++ GAD + ENE+P+ +P P +
Sbjct: 648 NGNTALHVAASLQYRLTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGE 700
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 96.7 bits (239), Expect = 9e-20
Identities = 110/377 (29%), Positives = 153/377 (40%), Gaps = 60/377 (15%)
Query: 483 AQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSV 542
A+D+ G PLH A +G V E +V H A VVN+ + TPLH A G+ +
Sbjct: 554 AKDKGGLVPLHNACSYGHYEVAELLVK--HGA----VVNVADLWKFTPLHEAAAKGKYEI 607
Query: 543 VSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLR---ALLQSGAPAV---------P 590
LL+ GADP +R G++ + L +LLR ALL + P
Sbjct: 608 CKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSP 667
Query: 591 QLLHMPDFEGLY--PVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELG 648
++ D +G + P+HLA + E + L+ GA+V A ++ GG LH A +
Sbjct: 668 DNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDK-GGLIPLHNAASYGHVD 726
Query: 649 LVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSP 708
V L+ K A VNA TPLH AA G L LLL GAD +N+E
Sbjct: 727 -VAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQE-------- 777
Query: 709 PTSDSDSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGL 768
G TPLDL + V LL A + P P
Sbjct: 778 ---------------------GQTPLDLVSADDVSALLTAAMPPSALPSCYKPQVLNGVR 816
Query: 769 SLGDTALQNLEQLLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSG----SLLRSYELA 824
S G TA + L GP + S + + L S SG S L E+
Sbjct: 817 SPGATA----DALSSGPSSPSSLSAASSLDNLSGSFSELSSVVSSSGTEGASSLEKKEVP 872
Query: 825 GGDLAGLLEALSDMGLE 841
G D + + + + ++GLE
Sbjct: 873 GVDFS-ITQFVRNLGLE 888
Score = 79.3 bits (194), Expect = 1e-14
Identities = 93/328 (28%), Positives = 134/328 (40%), Gaps = 36/328 (10%)
Query: 402 GGGAQMAATVPSRDSGEEAAEPSAPSRTPQCEPQAPEMLQRA---REYNAR-LFGLAQRS 457
GGGA A+ + EA EP+A C E ++R + N+R G
Sbjct: 8 GGGAACAS------AAAEAVEPAARELFEACRNGDVERVKRLVTPEKVNSRDTAGRKSTP 61
Query: 458 ARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDL 517
+G LL ++ A+D+ G PLH A G V+ + + H D
Sbjct: 62 LHFAAGFGRKDVVEYLLQNGANV-QARDDGGLIPLHNACSFGHAEVVNLL---LRHGAD- 116
Query: 518 GVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLA-------LRA 570
N ++ + TPLH A I G+ V LL+ GA+P + + G +A+ LA L
Sbjct: 117 --PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTG 174
Query: 571 GAGAPELLRALLQSGAPAVPQLL-------HMPDFEGLYPVHLAVRARSPECLDLLVDSG 623
ELL + + LL H D P+HLA + + LL+ G
Sbjct: 175 EYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHG 234
Query: 624 AEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTL 683
A+V A ++ G LH A VT L+ K A VNA TPLH AA +
Sbjct: 235 ADVHAKDK-GDLVPLHNACSYGHYE-VTELLVKHGACVNAMDLWQFTPLHEAASKNRVEV 292
Query: 684 TRLLLKAGAD---IHAENEEPLCPLPSP 708
LLL GAD ++ N+ + P+P
Sbjct: 293 CSLLLSYGADPTLLNCHNKSAIDLAPTP 320
Score = 75.9 bits (185), Expect = 2e-13
Identities = 75/245 (30%), Positives = 104/245 (42%), Gaps = 28/245 (11%)
Query: 490 TPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRV 549
TPLH+A V+E V V H A+ VN ++L QT LH A G LL
Sbjct: 402 TPLHVASEKAHNDVVE--VVVKHEAK----VNALDNLGQTSLHRAAYCGHLQTCRLLLSY 455
Query: 550 GADPALLDRHGDSAMHLA-------LRAGA--GAPELLRALLQSGAPA---------VPQ 591
G DP ++ G +A+ + L+ G G E R LL++ Q
Sbjct: 456 GCDPNIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQ 515
Query: 592 LLHMPDFEGLY--PVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGL 649
++ D EG P+H A ++ L+ GA+V A ++ GG LH A
Sbjct: 516 SVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDK-GGLVPLHNACSYGHYE- 573
Query: 650 VTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPP 709
V L+ K A VN TPLH AA G + +LLL+ GAD +N + PL
Sbjct: 574 VAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVK 633
Query: 710 TSDSD 714
D+D
Sbjct: 634 DGDTD 638
Score = 71.2 bits (173), Expect = 4e-12
Identities = 72/228 (31%), Positives = 100/228 (43%), Gaps = 25/228 (10%)
Query: 483 AQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSV 542
A+D+ PLH A +G V E +V H A VN + TPLH A + V
Sbjct: 239 AKDKGDLVPLHNACSYGHYEVTELLVK--HGA----CVNAMDLWQFTPLHEAASKNRVEV 292
Query: 543 VSFLLRVGADPALLDRHGDSAMHLA--------LRAGAGAPELLRALLQSGAPAVPQLLH 594
S LL GADP LL+ H SA+ LA L LL+A ++ + + L
Sbjct: 293 CSLLLSYGADPTLLNCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLS 352
Query: 595 MPDFEGLYP------VHLAVRARSP---ECLDLLVDSGAEVEATERQGGRTALHLATEME 645
+ +P +H A + P + +LL+ GA + ++ T LH+A+E
Sbjct: 353 LEMVNFKHPQTHETALHCAAASPYPKRKQICELLLRKGANINEKTKE-FLTPLHVASEKA 411
Query: 646 ELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGAD 693
+V +V K A VNA G T LH AA G+ RLLL G D
Sbjct: 412 HNDVV-EVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCD 458
Score = 47.0 bits (110), Expect = 8e-05
Identities = 37/116 (31%), Positives = 57/116 (49%), Gaps = 9/116 (7%)
Query: 481 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 540
+ AQD+ G PLH A +G V ++ + VN T+ TPLH A G+T
Sbjct: 705 VNAQDKGGLIPLHNAASYGHVDVAALLI------KYNACVNATDKWAFTPLHEAAQKGRT 758
Query: 541 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAV--PQLLH 594
+ + LL GADP L ++ G + + L + A + L A+ S P+ PQ+L+
Sbjct: 759 QLCALLLAHGADPTLKNQEGQTPLDL-VSADDVSALLTAAMPPSALPSCYKPQVLN 813
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 92.8 bits (229), Expect = 1e-18
Identities = 101/373 (27%), Positives = 153/373 (41%), Gaps = 57/373 (15%)
Query: 483 AQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSV 542
A+D+ G PLH A +G V E +V H + V +L TPLH A G+ +
Sbjct: 712 AKDKGGLVPLHNACSYGHYEVAELLV---RHGASVNVADLWKF---TPLHEAAAKGKYEI 765
Query: 543 VSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLR---ALLQSGAPA---------VP 590
LL+ GADP +R G++ + L +LLR ALL + P
Sbjct: 766 CKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTP 825
Query: 591 QLLHMPDFEGLY--PVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELG 648
+ ++ D +G P+HLA + E + L++ GA+V A ++ GG LH A +
Sbjct: 826 ENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDK-GGLIPLHNAASYGHVD 884
Query: 649 LVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSP 708
+ L+ K VNA TPLH AA G L LLL GAD +N+E
Sbjct: 885 IAALLI-KYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQE-------- 935
Query: 709 PTSDSDSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGL 768
G TPLDL + ++ LL++A PP P+ P
Sbjct: 936 ---------------------GQTPLDLATADDIRALLIDAM-----PPEALPTCFKPQA 969
Query: 769 SLGDTALQNLEQLLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDL 828
++ +L + A S L L ++ +G+ + E+AG D+
Sbjct: 970 TVVSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAGDGAAGTERKEGEVAGLDM 1029
Query: 829 AGLLEALSDMGLE 841
+ + L +GLE
Sbjct: 1030 -NISQFLKSLGLE 1041
Score = 73.9 bits (180), Expect = 6e-13
Identities = 71/245 (28%), Positives = 103/245 (42%), Gaps = 28/245 (11%)
Query: 490 TPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRV 549
TPLH+A V+E V+H + +N + L QT LH A + G LL
Sbjct: 560 TPLHVAAERAHNDVME----VLH--KHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSY 613
Query: 550 GADPALLDRHGDSAMHLA-------------LRAGAGAPELLRALLQSGAPAVPQL---- 592
G+DP+++ G +A + +R LL A V QL
Sbjct: 614 GSDPSIISLQGFTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQ 673
Query: 593 -LHMPDFEGLY--PVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGL 649
++ D EG + P+H A ++ L+ GA+V A ++ GG LH A
Sbjct: 674 NVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDK-GGLVPLHNACSYGHYE- 731
Query: 650 VTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPP 709
V L+ + A+VN TPLH AA G + +LLLK GAD +N + PL
Sbjct: 732 VAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVK 791
Query: 710 TSDSD 714
D+D
Sbjct: 792 EGDTD 796
Score = 72.4 bits (176), Expect = 2e-12
Identities = 71/230 (30%), Positives = 103/230 (44%), Gaps = 35/230 (15%)
Query: 481 LTAQDENG--DTPLHLAIIHGQTSVIEQIVYV---IHHAQDLGVVNLTNHLHQTPLHLAV 535
+ A+D G +PLH A G+ V+E ++ + +H D G++ PLH A
Sbjct: 207 VNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLI---------PLHNAC 257
Query: 536 ITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHM 595
G VVS LL GADP D + +H A A G ++ LLQ GA ++
Sbjct: 258 SFGHAEVVSLLLCQGADPNARDNWNYTPLHEA--AIKGKIDVCIVLLQHGADP-----NI 310
Query: 596 PDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVT 655
+ +G + LA D A+ T L A E L+ L+T
Sbjct: 311 RNTDGKSALDLA-------------DPSAKAVLTGEYKKDELLEAARSGNEEKLMA-LLT 356
Query: 656 KLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
L N +A +TPLHLAAG + +LLL+ GAD+HA+++ L PL
Sbjct: 357 PLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPL 406
Score = 69.7 bits (169), Expect = 1e-11
Identities = 72/228 (31%), Positives = 101/228 (44%), Gaps = 25/228 (10%)
Query: 483 AQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSV 542
A+D+ G PLH A +G V E ++ H A VN + TPLH A + V
Sbjct: 397 AKDKGGLVPLHNACSYGHYEVTELLLK--HGA----CVNAMDLWQFTPLHEAASKNRVEV 450
Query: 543 VSFLLRVGADPALLDRHGDSAMHLA--------LRAGAGAPELLRALLQSGAPAVPQLLH 594
S LL GADP L++ HG SA+ +A L LL+A ++ V + L
Sbjct: 451 CSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLA 510
Query: 595 MPDFEGLYP------VHLAVRARSP---ECLDLLVDSGAEVEATERQGGRTALHLATEME 645
+ P +H AV + P + +LL+ GA V + + T LH+A E
Sbjct: 511 LEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVN-EKNKDFMTPLHVAAERA 569
Query: 646 ELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGAD 693
V ++ K A +NA G T LH AA G+ RLLL G+D
Sbjct: 570 H-NDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSD 616
Score = 62.8 bits (151), Expect = 1e-09
Identities = 68/224 (30%), Positives = 103/224 (45%), Gaps = 29/224 (12%)
Query: 483 AQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSV 542
A+D+ G PLH A G V+ ++ D N ++ + TPLH A I G+ V
Sbjct: 244 ARDDGGLIPLHNACSFGHAEVVSLLLC---QGAD---PNARDNWNYTPLHEAAIKGKIDV 297
Query: 543 VSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLY 602
LL+ GADP + + G SA+ LA + +A+L +G +LL
Sbjct: 298 CIVLLQHGADPNIRNTDGKSALDLADPSA-------KAVL-TGEYKKDELLE-------- 341
Query: 603 PVHLAVRARSPECL-DLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANV 661
A R+ + E L LL A++ + T LHLA + +V L+ + A+V
Sbjct: 342 ----AARSGNEEKLMALLTPLNVNCHASDGRKS-TPLHLAAGYNRVRIV-QLLLQHGADV 395
Query: 662 NARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
+A+ G PLH A G+ +T LLLK GA ++A + PL
Sbjct: 396 HAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPL 439
Score = 61.2 bits (147), Expect = 4e-09
Identities = 64/226 (28%), Positives = 100/226 (44%), Gaps = 26/226 (11%)
Query: 484 QDENGDTPLHLAI--IHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTS 541
Q ++ +T LH A+ +H + + +++ + VN N TPLH+A
Sbjct: 518 QPQSHETALHCAVASLHPKRKQVTELLL-----RKGANVNEKNKDFMTPLHVAAERAHND 572
Query: 542 VVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGL 601
V+ L + GA LD G +A+H A A AG + R LL G+ P ++ + F
Sbjct: 573 VMEVLHKHGAKMNALDTLGQTALHRA--ALAGHLQTCRLLLSYGSD--PSIISLQGFTAA 628
Query: 602 YPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANV 661
+ AV+ E + S + E A++ +L V L + NV
Sbjct: 629 QMGNEAVQQILSESTPIRT-SDVDYRLLE----------ASKAGDLETVKQLCSS--QNV 675
Query: 662 NARTFAG--NTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
N R G +TPLH AAG ++ LL GAD+HA+++ L PL
Sbjct: 676 NCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPL 721
Score = 52.4 bits (124), Expect = 2e-06
Identities = 72/244 (29%), Positives = 98/244 (40%), Gaps = 32/244 (13%)
Query: 468 ADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLH 527
A+ +LL Q A+D TPLH A I G+ I+ + ++ H D N+ N
Sbjct: 262 AEVVSLLLCQGADPNARDNWNYTPLHEAAIKGK---IDVCIVLLQHGAD---PNIRNTDG 315
Query: 528 QTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAP 587
++ L LA S + L LL+ A +G E L ALL
Sbjct: 316 KSALDLA----DPSAKAVLTGEYKKDELLE-----------AARSGNEEKLMALL----T 356
Query: 588 AVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEEL 647
+ H D P+HLA + LL+ GA+V A ++ GG LH A
Sbjct: 357 PLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDK-GGLVPLHNACSYGHY 415
Query: 648 GLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGAD-----IHAENEEPL 702
VT L+ K A VNA TPLH AA + LLL GAD H ++ +
Sbjct: 416 E-VTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDM 474
Query: 703 CPLP 706
P P
Sbjct: 475 APTP 478
Score = 47.0 bits (110), Expect = 8e-05
Identities = 49/190 (25%), Positives = 79/190 (41%), Gaps = 33/190 (17%)
Query: 481 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 540
+ AQD+ G PLH A +G + ++ + VN T+ TPLH A G+T
Sbjct: 863 VNAQDKGGLIPLHNAASYGHVDIAALLI------KYNTCVNATDKWAFTPLHEAAQKGRT 916
Query: 541 SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG 600
+ + LL GADP + ++ G + + LA + +RALL P
Sbjct: 917 QLCALLLAHGADPTMKNQEGQTPLDLA------TADDIRALLIDAMPPEALPTCFKPQAT 970
Query: 601 LYPVHLAVRARSPECL--------------DLLV----DSGAEVEATERQGGRTA---LH 639
+ L A +P CL +L V ++G TER+ G A ++
Sbjct: 971 VVSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAGDGAAGTERKEGEVAGLDMN 1030
Query: 640 LATEMEELGL 649
++ ++ LGL
Sbjct: 1031 ISQFLKSLGL 1040
Score = 44.7 bits (104), Expect = 4e-04
Identities = 23/49 (46%), Positives = 32/49 (65%), Gaps = 2/49 (4%)
Query: 659 ANVNARTFAG--NTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
ANVNA+ AG ++PLH AAG G + LL+ GA++HA ++ L PL
Sbjct: 205 ANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPL 253
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 90.9 bits (224), Expect = 5e-18
Identities = 106/412 (25%), Positives = 166/412 (40%), Gaps = 65/412 (15%)
Query: 483 AQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSV 542
A +G TPLHL+ G V +++ H L + T TPLH+A G+ V
Sbjct: 527 AATTSGYTPLHLSAREGHEDVA---AFLLDHGASLSI---TTKKGFTPLHVAAKYGKLEV 580
Query: 543 VSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLY 602
+ LL+ A P + G + +H+A LL LL GA H G
Sbjct: 581 ANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALL--LLDQGASP-----HAAAKNGYT 633
Query: 603 PVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVN 662
P+H+A + + L++ GA+ A RQG ++HLA + + +V+ L+ + ANVN
Sbjct: 634 PLHIAAKKNQMDIATTLLEYGADANAVTRQG-IASVHLAAQEGHVDMVSLLLGR-NANVN 691
Query: 663 ARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEK 722
+G TPLHLAA + +L+ GA + A+ +
Sbjct: 692 LSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTK----------------------- 728
Query: 723 DTRSSFRGHTPLDLTC---STKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNL- 778
G+TPL + C + K+ LL + +P G T + N+
Sbjct: 729 ------MGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 782
Query: 779 --------EQLLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAG 830
E ++G A G +A RLG S+VDT + T + + E ++
Sbjct: 783 LQNNASPNELTVNGNTALG----IARRLGYISVVDTLKIVTEETMTTTTVTEKHKMNVPE 838
Query: 831 LLEALSDMGLEEGVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEK-LGP 881
+ + DM +E VR PE L E D G ++ + +K LGP
Sbjct: 839 TMNEVLDMSDDE-VRKANAPE---MLSDGEYISDVEEGEDAMTGDTDKYLGP 886
Score = 90.5 bits (223), Expect = 6e-18
Identities = 81/276 (29%), Positives = 125/276 (45%), Gaps = 51/276 (18%)
Query: 458 ARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDL 517
A+ LLD +A+AL NG TPLH+A + V+E + + H +
Sbjct: 383 AKVLLDKKANPNAKAL-------------NGFTPLHIACKKNRIKVMELL---LKHGASI 426
Query: 518 GVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPEL 577
V + TP+H+A G ++VS L+ GA P + G++A+H+A R+G E+
Sbjct: 427 QAVTESG---LTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQA--EV 481
Query: 578 LRALLQSGAPA----------------------VPQLL------HMPDFEGLYPVHLAVR 609
+R L+Q GA V QLL + G P+HL+ R
Sbjct: 482 VRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAR 541
Query: 610 ARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGN 669
+ L+D GA + T ++ G T LH+A + +L V +L+ + A+ +A +G
Sbjct: 542 EGHEDVAAFLLDHGASLSITTKK-GFTPLHVAAKYGKLE-VANLLLQKSASPDAAGKSGL 599
Query: 670 TPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
TPLH+AA + LLL GA HA + PL
Sbjct: 600 TPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPL 635
Score = 86.7 bits (213), Expect = 9e-17
Identities = 71/236 (30%), Positives = 107/236 (45%), Gaps = 15/236 (6%)
Query: 470 ARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQT 529
A ALL + + ++G TPLH+A +G +V ++ V+ T T
Sbjct: 217 AAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLL------NRAAAVDFTARNDIT 270
Query: 530 PLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAV 589
PLH+A G ++V LL GA R G + +H R+G +++ LL AP +
Sbjct: 271 PLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGH--EQVVEMLLDRAAPIL 328
Query: 590 PQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGL 649
+ + GL P+H+A + C+ LL+ V+ TALH+A +
Sbjct: 329 SKTKN-----GLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDY-LTALHVAAHCGHYKV 382
Query: 650 VTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
L+ K +AN NA+ G TPLH+A + LLLK GA I A E L P+
Sbjct: 383 AKVLLDK-KANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPI 437
Score = 75.1 bits (183), Expect = 3e-13
Identities = 71/228 (31%), Positives = 106/228 (46%), Gaps = 29/228 (12%)
Query: 483 AQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSV 542
A + G+T LH+A + GQ V++ V V + A VN + TPL++A V
Sbjct: 102 AATKKGNTALHIASLAGQAEVVK--VLVTNGAN----VNAQSQNGFTPLYMAAQENHLEV 155
Query: 543 VSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG-- 600
V FLL GA +L G + + +A LQ G V LL D +G
Sbjct: 156 VKFLLDNGASQSLATEDGFTPLAVA--------------LQQGHDQVVSLLLENDTKGKV 201
Query: 601 -LYPVHLAVRARSPECLDLLV--DSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKL 657
L +H+A R + LL+ D+ A+VE+ + G T LH+A + + T L+ +
Sbjct: 202 RLPALHIAARKDDTKAAALLLQNDNNADVES---KSGFTPLHIAAHYGNINVATLLLNRA 258
Query: 658 RANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
A V+ TPLH+A+ G + +LLL GA I A+ + L PL
Sbjct: 259 AA-VDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPL 305
Score = 64.3 bits (155), Expect = 5e-10
Identities = 78/268 (29%), Positives = 118/268 (44%), Gaps = 37/268 (13%)
Query: 453 LAQRSAR--ALLDYGVTADARALLAGQRHLL----------TAQDENGDTPLHLAIIHGQ 500
L QR A A G TA A LAGQ ++ AQ +NG TPL++A Q
Sbjct: 93 LLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMA---AQ 149
Query: 501 TSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHG 560
+ +E + +++ + +L TPL +A+ G VVS LL D G
Sbjct: 150 ENHLEVVKFLLDNGAS---QSLATEDGFTPLAVALQQGHDQVVSLLLE-------NDTKG 199
Query: 561 D---SAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLD 617
A+H+A R L LLQ+ A + G P+H+A +
Sbjct: 200 KVRLPALHIAARKDDTKAAAL--LLQNDNNA-----DVESKSGFTPLHIAAHYGNINVAT 252
Query: 618 LLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAG 677
LL++ A V+ T R T LH+A++ +V L+ + A ++A+T G TPLH A
Sbjct: 253 LLLNRAAAVDFTAR-NDITPLHVASKRGNANMVKLLLDR-GAKIDAKTRDGLTPLHCGAR 310
Query: 678 LGYPTLTRLLLKAGADIHAENEEPLCPL 705
G+ + +LL A I ++ + L PL
Sbjct: 311 SGHEQVVEMLLDRAAPILSKTKNGLSPL 338
Score = 61.6 bits (148), Expect = 3e-09
Identities = 69/272 (25%), Positives = 104/272 (38%), Gaps = 69/272 (25%)
Query: 469 DARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLH- 527
D A L L+ + G TPLH+A +G+ V ++ G LT LH
Sbjct: 546 DVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTP-LHV 604
Query: 528 ---------------------------QTPLHLAVITGQTSVVSFLLRVGADPALLDRHG 560
TPLH+A Q + + LL GAD + R G
Sbjct: 605 AAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQG 664
Query: 561 DSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLV 620
+++HLA A G +++ LL A +++ + GL P+HLA + ++LV
Sbjct: 665 IASVHLA--AQEGHVDMVSLLLGRNAN-----VNLSNKSGLTPLHLAAQEDRVNVAEVLV 717
Query: 621 DSGAEVEATERQGGRTALHLATEMEELGLV-----------------------------T 651
+ GA V+A + G T LH+ + +V T
Sbjct: 718 NQGAHVDAQTKMG-YTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHT 776
Query: 652 HLVTKL---RANVNARTFAGNTPLHLAAGLGY 680
H++ L A+ N T GNT L +A LGY
Sbjct: 777 HIINVLLQNNASPNELTVNGNTALGIARRLGY 808
Score = 57.8 bits (138), Expect = 5e-08
Identities = 60/213 (28%), Positives = 93/213 (43%), Gaps = 34/213 (15%)
Query: 520 VNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLR 579
+N+ N LHLA G VVS LL+ A+ + G++A+H+A + AG E+++
Sbjct: 67 INICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIA--SLAGQAEVVK 124
Query: 580 ALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVE-ATE-------- 630
L+ +GA Q G P+++A + E + L+D+GA ATE
Sbjct: 125 VLVTNGANVNAQ-----SQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAV 179
Query: 631 --RQGGRTALHLATEMEELGLV----THLV-----TKLRA-------NVNARTFAGNTPL 672
+QG + L E + G V H+ TK A N + + +G TPL
Sbjct: 180 ALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPL 239
Query: 673 HLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
H+AA G + LLL A + + PL
Sbjct: 240 HIAAHYGNINVATLLLNRAAAVDFTARNDITPL 272
Score = 48.1 bits (113), Expect = 4e-05
Identities = 59/214 (27%), Positives = 99/214 (46%), Gaps = 26/214 (12%)
Query: 547 LRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHL 606
++ G D + +++G +A+HLA + G E++ LLQ A + +G +H+
Sbjct: 61 IKNGVDINICNQNGLNALHLASK--EGHVEVVSELLQREAN-----VDAATKKGNTALHI 113
Query: 607 AVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTF 666
A A E + +LV +GA V A + Q G T L++A + L +V L+ A+ + T
Sbjct: 114 ASLAGQAEVVKVLVTNGANVNA-QSQNGFTPLYMAAQENHLEVVKFLLDN-GASQSLATE 171
Query: 667 AGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP----EK 722
G TPL +A G+ + LLL+ + + LP+ + D++ +
Sbjct: 172 DGFTPLAVALQQGHDQVVSLLLE-------NDTKGKVRLPALHIAARKDDTKAAALLLQN 224
Query: 723 DTRS---SFRGHTPLDLTC---STKVKTLLLNAA 750
D + S G TPL + + V TLLLN A
Sbjct: 225 DNNADVESKSGFTPLHIAAHYGNINVATLLLNRA 258
>gi|30348954 mindbomb homolog 1 [Homo sapiens]
Length = 1006
Score = 90.5 bits (223), Expect = 6e-18
Identities = 71/239 (29%), Positives = 114/239 (47%), Gaps = 15/239 (6%)
Query: 469 DARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQ 528
D LL Q + A+D++GD +H A + +VIE V+H +N N Q
Sbjct: 478 DILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIE----VLHRGS--ADLNARNKRRQ 531
Query: 529 TPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPA 588
TPLH+AV G VV LL G P+L D GD+ +H A+ ++L LL++GA
Sbjct: 532 TPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAI--SKKRDDILAVLLEAGADV 589
Query: 589 VPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAE--VEATERQGGRTALHLATEMEE 646
+ + G +H A +P + +L+ + ++ G TALHLA
Sbjct: 590 T-----ITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNH 644
Query: 647 LGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
+ + LV + AN++ + T LHLA + + RLL++AGA + ++++ PL
Sbjct: 645 VEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPL 703
Score = 55.1 bits (131), Expect = 3e-07
Identities = 69/275 (25%), Positives = 105/275 (38%), Gaps = 53/275 (19%)
Query: 480 LLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQ 539
++ + ++G T LHLA ++ V E +V+ + D+ VN QT LHLAV
Sbjct: 624 IVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVN-----QQTALHLAVERQH 678
Query: 540 TSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFE 599
T +V L+R GA + D+ GD+ +H ALR + QL + D +
Sbjct: 679 TQIVRLLVRAGAKLDIQDKDGDTPLHEALR----------------HHTLSQLRQLQDMQ 722
Query: 600 GLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRA 659
+ V A + L GAE ++ A LA A
Sbjct: 723 DVGKVDAAWEPSKNTLIMGLGTQGAE----KKSAASIACFLAAN--------------GA 764
Query: 660 NVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDS-- 717
+++ R G +PL L P L + L K H E SP +DS++
Sbjct: 765 DLSIRNKKGQSPLDLCPD---PNLCKALAKC----HKEKVSGQVGSRSPSMISNDSETLE 817
Query: 718 -----EGPEKDTRSSFRGHTPLDLTCSTKVKTLLL 747
++DT GH CS +VK L+
Sbjct: 818 ECMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLI 852
>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
Length = 1897
Score = 90.1 bits (222), Expect = 8e-18
Identities = 76/242 (31%), Positives = 112/242 (46%), Gaps = 16/242 (6%)
Query: 464 YGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLT 523
YG A LL H A +NG TPLH+A+ H +++ ++ G +
Sbjct: 579 YGKVRVAELLLERDAHP-NAAGKNGLTPLHVAVHHNNLDIVKLLL------PRGGSPHSP 631
Query: 524 NHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQ 583
TPLH+A Q V LL+ G G + +HLA A G E++ LL
Sbjct: 632 AWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLA--AQEGHAEMVALLLS 689
Query: 584 SGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATE 643
A ++ + GL P+HL + D+L+ G V+AT R G T LH+A+
Sbjct: 690 KQANG-----NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMG-YTPLHVASH 743
Query: 644 MEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLC 703
+ LV L+ +A+VNA+T G +PLH AA G+ + LLLK GA + + +
Sbjct: 744 YGNIKLVKFLLQH-QADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 802
Query: 704 PL 705
PL
Sbjct: 803 PL 804
Score = 83.2 bits (204), Expect = 1e-15
Identities = 66/217 (30%), Positives = 103/217 (47%), Gaps = 15/217 (6%)
Query: 489 DTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLR 548
+TPLH+A G T V + ++ Q+ VN QTPLH A G T++V LL
Sbjct: 471 ETPLHMAARAGHTEVAKYLL------QNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE 524
Query: 549 VGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAV 608
A+P L G + +H+A R G E + ALL+ A +G P+H+A
Sbjct: 525 NNANPNLATTAGHTPLHIAAR--EGHVETVLALLEKEASQACMTK-----KGFTPLHVAA 577
Query: 609 RARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAG 668
+ +LL++ A A + G T LH+A L +V L+ + + ++ + G
Sbjct: 578 KYGKVRVAELLLERDAHPNAAGK-NGLTPLHVAVHHNNLDIVKLLLPR-GGSPHSPAWNG 635
Query: 669 NTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
TPLH+AA + R LL+ G +AE+ + + PL
Sbjct: 636 YTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 672
Score = 76.6 bits (187), Expect = 9e-14
Identities = 83/286 (29%), Positives = 118/286 (41%), Gaps = 47/286 (16%)
Query: 486 ENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGV-VNLTNHLHQTPLHLAVITGQTSVVS 544
+ G TPLH+A + +V + ++ + G VN T TPLH+A G +V
Sbjct: 237 KTGFTPLHIAAHYENLNVAQLLL-------NRGASVNFTPQNGITPLHIASRRGNVIMVR 289
Query: 545 FLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPV 604
LL GA + + +H A R G + LL GAP + GL P+
Sbjct: 290 LLLDRGAQIETKTKDELTPLHCAARNGH--VRISEILLDHGAP-----IQAKTKNGLSPI 342
Query: 605 HLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR 664
H+A + +C+ LL+ AE++ T LH+A + L+ K A N+R
Sbjct: 343 HMAAQGDHLDCVRLLLQYDAEIDDITLDH-LTPLHVAAHCGHHRVAKVLLDK-GAKPNSR 400
Query: 665 TFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDT 724
G TPLH+A + + LLLK GA I A E L PL
Sbjct: 401 ALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHV----------------- 443
Query: 725 RSSFRGHTPLDLTCSTKVKTLLL-----NAAQNTMEPPLTPPSPAG 765
+SF GH P+ VK LL N + +E PL + AG
Sbjct: 444 -ASFMGHLPI-------VKNLLQRGASPNVSNVKVETPLHMAARAG 481
Score = 73.9 bits (180), Expect = 6e-13
Identities = 64/227 (28%), Positives = 102/227 (44%), Gaps = 21/227 (9%)
Query: 480 LLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGV-VNLTNHLHQTPLHLAVITG 538
+L + G+T LH+A + GQ V+ ++V + G VN + TPL++A
Sbjct: 103 ILETTTKKGNTALHIAALAGQDEVVRELV-------NYGANVNAQSQKGFTPLYMAAQEN 155
Query: 539 QTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDF 598
VV FLL GA+ + G + + +AL+ G ++ L+ G +L +
Sbjct: 156 HLEVVKFLLENGANQNVATEDGFTPLAVALQQGH--ENVVAHLINYGTKGKVRLPAL--- 210
Query: 599 EGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLR 658
H+A R +L+ + + + G T LH+A E L V L+
Sbjct: 211 ------HIAARNDDTRTAAVLLQNDPNPDVLSKTGF-TPLHIAAHYENLN-VAQLLLNRG 262
Query: 659 ANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
A+VN G TPLH+A+ G + RLLL GA I + ++ L PL
Sbjct: 263 ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 309
Score = 53.5 bits (127), Expect = 9e-07
Identities = 57/214 (26%), Positives = 91/214 (42%), Gaps = 36/214 (16%)
Query: 520 VNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLR 579
+N N LHLA G +V LL + G++A+H+A A AG E++R
Sbjct: 71 INTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIA--ALAGQDEVVR 128
Query: 580 ALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALH 639
L+ GA Q +G P+++A + E + L+++GA + + G T L
Sbjct: 129 ELVNYGANVNAQ-----SQKGFTPLYMAAQENHLEVVKFLLENGAN-QNVATEDGFTPLA 182
Query: 640 LATEMEELGLVTHLVT-----KLR--------ANVNARTFA---------------GNTP 671
+A + +V HL+ K+R N + RT A G TP
Sbjct: 183 VALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTP 242
Query: 672 LHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
LH+AA + +LLL GA ++ + + PL
Sbjct: 243 LHIAAHYENLNVAQLLLNRGASVNFTPQNGITPL 276
Score = 50.4 bits (119), Expect = 7e-06
Identities = 48/149 (32%), Positives = 71/149 (47%), Gaps = 28/149 (18%)
Query: 458 ARALLDYGVTADARA--------LLAGQRH-----LLTAQDENGD-------TPLHLAII 497
AR+LL YG +A+A + L A + H LL ++ NG+ TPLHL
Sbjct: 651 ARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQ 710
Query: 498 HGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLD 557
G V + V + H +V+ T + TPLH+A G +V FLL+ AD
Sbjct: 711 EGHVPVAD--VLIKHGV----MVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 764
Query: 558 RHGDSAMHLALRAGAGAPELLRALLQSGA 586
+ G S +H A A G +++ LL++GA
Sbjct: 765 KLGYSPLHQA--AQQGHTDIVTLLLKNGA 791
Score = 48.5 bits (114), Expect = 3e-05
Identities = 34/114 (29%), Positives = 53/114 (46%), Gaps = 19/114 (16%)
Query: 458 ARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDL 517
A L+ +GV DA + G TPLH+A +G +++ +++ H D
Sbjct: 717 ADVLIKHGVMVDATTRM-------------GYTPLHVASHYGNIKLVK---FLLQHQAD- 759
Query: 518 GVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAG 571
VN L +PLH A G T +V+ LL+ GA P + G + + +A R G
Sbjct: 760 --VNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLG 811
>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
Length = 1881
Score = 90.1 bits (222), Expect = 8e-18
Identities = 76/242 (31%), Positives = 112/242 (46%), Gaps = 16/242 (6%)
Query: 464 YGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLT 523
YG A LL H A +NG TPLH+A+ H +++ ++ G +
Sbjct: 546 YGKVRVAELLLERDAHP-NAAGKNGLTPLHVAVHHNNLDIVKLLL------PRGGSPHSP 598
Query: 524 NHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQ 583
TPLH+A Q V LL+ G G + +HLA A G E++ LL
Sbjct: 599 AWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLA--AQEGHAEMVALLLS 656
Query: 584 SGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATE 643
A ++ + GL P+HL + D+L+ G V+AT R G T LH+A+
Sbjct: 657 KQANG-----NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMG-YTPLHVASH 710
Query: 644 MEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLC 703
+ LV L+ +A+VNA+T G +PLH AA G+ + LLLK GA + + +
Sbjct: 711 YGNIKLVKFLLQH-QADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Query: 704 PL 705
PL
Sbjct: 770 PL 771
Score = 83.2 bits (204), Expect = 1e-15
Identities = 66/217 (30%), Positives = 103/217 (47%), Gaps = 15/217 (6%)
Query: 489 DTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLR 548
+TPLH+A G T V + ++ Q+ VN QTPLH A G T++V LL
Sbjct: 438 ETPLHMAARAGHTEVAKYLL------QNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE 491
Query: 549 VGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAV 608
A+P L G + +H+A R G E + ALL+ A +G P+H+A
Sbjct: 492 NNANPNLATTAGHTPLHIAAR--EGHVETVLALLEKEASQACMTK-----KGFTPLHVAA 544
Query: 609 RARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAG 668
+ +LL++ A A + G T LH+A L +V L+ + + ++ + G
Sbjct: 545 KYGKVRVAELLLERDAHPNAAGK-NGLTPLHVAVHHNNLDIVKLLLPR-GGSPHSPAWNG 602
Query: 669 NTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
TPLH+AA + R LL+ G +AE+ + + PL
Sbjct: 603 YTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 639
Score = 76.6 bits (187), Expect = 9e-14
Identities = 83/286 (29%), Positives = 118/286 (41%), Gaps = 47/286 (16%)
Query: 486 ENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGV-VNLTNHLHQTPLHLAVITGQTSVVS 544
+ G TPLH+A + +V + ++ + G VN T TPLH+A G +V
Sbjct: 204 KTGFTPLHIAAHYENLNVAQLLL-------NRGASVNFTPQNGITPLHIASRRGNVIMVR 256
Query: 545 FLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPV 604
LL GA + + +H A R G + LL GAP + GL P+
Sbjct: 257 LLLDRGAQIETKTKDELTPLHCAARNGH--VRISEILLDHGAP-----IQAKTKNGLSPI 309
Query: 605 HLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR 664
H+A + +C+ LL+ AE++ T LH+A + L+ K A N+R
Sbjct: 310 HMAAQGDHLDCVRLLLQYDAEIDDITLDH-LTPLHVAAHCGHHRVAKVLLDK-GAKPNSR 367
Query: 665 TFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDT 724
G TPLH+A + + LLLK GA I A E L PL
Sbjct: 368 ALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHV----------------- 410
Query: 725 RSSFRGHTPLDLTCSTKVKTLLL-----NAAQNTMEPPLTPPSPAG 765
+SF GH P+ VK LL N + +E PL + AG
Sbjct: 411 -ASFMGHLPI-------VKNLLQRGASPNVSNVKVETPLHMAARAG 448
Score = 73.9 bits (180), Expect = 6e-13
Identities = 64/227 (28%), Positives = 102/227 (44%), Gaps = 21/227 (9%)
Query: 480 LLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGV-VNLTNHLHQTPLHLAVITG 538
+L + G+T LH+A + GQ V+ ++V + G VN + TPL++A
Sbjct: 70 ILETTTKKGNTALHIAALAGQDEVVRELV-------NYGANVNAQSQKGFTPLYMAAQEN 122
Query: 539 QTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDF 598
VV FLL GA+ + G + + +AL+ G ++ L+ G +L +
Sbjct: 123 HLEVVKFLLENGANQNVATEDGFTPLAVALQQGH--ENVVAHLINYGTKGKVRLPAL--- 177
Query: 599 EGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLR 658
H+A R +L+ + + + G T LH+A E L V L+
Sbjct: 178 ------HIAARNDDTRTAAVLLQNDPNPDVLSKTGF-TPLHIAAHYENLN-VAQLLLNRG 229
Query: 659 ANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
A+VN G TPLH+A+ G + RLLL GA I + ++ L PL
Sbjct: 230 ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 276
Score = 53.5 bits (127), Expect = 9e-07
Identities = 57/214 (26%), Positives = 91/214 (42%), Gaps = 36/214 (16%)
Query: 520 VNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLR 579
+N N LHLA G +V LL + G++A+H+A A AG E++R
Sbjct: 38 INTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIA--ALAGQDEVVR 95
Query: 580 ALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALH 639
L+ GA Q +G P+++A + E + L+++GA + + G T L
Sbjct: 96 ELVNYGANVNAQ-----SQKGFTPLYMAAQENHLEVVKFLLENGAN-QNVATEDGFTPLA 149
Query: 640 LATEMEELGLVTHLVT-----KLR--------ANVNARTFA---------------GNTP 671
+A + +V HL+ K+R N + RT A G TP
Sbjct: 150 VALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTP 209
Query: 672 LHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
LH+AA + +LLL GA ++ + + PL
Sbjct: 210 LHIAAHYENLNVAQLLLNRGASVNFTPQNGITPL 243
Score = 50.4 bits (119), Expect = 7e-06
Identities = 48/149 (32%), Positives = 71/149 (47%), Gaps = 28/149 (18%)
Query: 458 ARALLDYGVTADARA--------LLAGQRH-----LLTAQDENGD-------TPLHLAII 497
AR+LL YG +A+A + L A + H LL ++ NG+ TPLHL
Sbjct: 618 ARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQ 677
Query: 498 HGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLD 557
G V + V + H +V+ T + TPLH+A G +V FLL+ AD
Sbjct: 678 EGHVPVAD--VLIKHGV----MVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 731
Query: 558 RHGDSAMHLALRAGAGAPELLRALLQSGA 586
+ G S +H A A G +++ LL++GA
Sbjct: 732 KLGYSPLHQA--AQQGHTDIVTLLLKNGA 758
Score = 48.5 bits (114), Expect = 3e-05
Identities = 34/114 (29%), Positives = 53/114 (46%), Gaps = 19/114 (16%)
Query: 458 ARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDL 517
A L+ +GV DA + G TPLH+A +G +++ +++ H D
Sbjct: 684 ADVLIKHGVMVDATTRM-------------GYTPLHVASHYGNIKLVK---FLLQHQAD- 726
Query: 518 GVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAG 571
VN L +PLH A G T +V+ LL+ GA P + G + + +A R G
Sbjct: 727 --VNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLG 778
>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
Length = 1880
Score = 90.1 bits (222), Expect = 8e-18
Identities = 76/242 (31%), Positives = 112/242 (46%), Gaps = 16/242 (6%)
Query: 464 YGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLT 523
YG A LL H A +NG TPLH+A+ H +++ ++ G +
Sbjct: 546 YGKVRVAELLLERDAHP-NAAGKNGLTPLHVAVHHNNLDIVKLLL------PRGGSPHSP 598
Query: 524 NHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQ 583
TPLH+A Q V LL+ G G + +HLA A G E++ LL
Sbjct: 599 AWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLA--AQEGHAEMVALLLS 656
Query: 584 SGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATE 643
A ++ + GL P+HL + D+L+ G V+AT R G T LH+A+
Sbjct: 657 KQANG-----NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMG-YTPLHVASH 710
Query: 644 MEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLC 703
+ LV L+ +A+VNA+T G +PLH AA G+ + LLLK GA + + +
Sbjct: 711 YGNIKLVKFLLQH-QADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Query: 704 PL 705
PL
Sbjct: 770 PL 771
Score = 83.2 bits (204), Expect = 1e-15
Identities = 66/217 (30%), Positives = 103/217 (47%), Gaps = 15/217 (6%)
Query: 489 DTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLR 548
+TPLH+A G T V + ++ Q+ VN QTPLH A G T++V LL
Sbjct: 438 ETPLHMAARAGHTEVAKYLL------QNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE 491
Query: 549 VGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAV 608
A+P L G + +H+A R G E + ALL+ A +G P+H+A
Sbjct: 492 NNANPNLATTAGHTPLHIAAR--EGHVETVLALLEKEASQACMTK-----KGFTPLHVAA 544
Query: 609 RARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAG 668
+ +LL++ A A + G T LH+A L +V L+ + + ++ + G
Sbjct: 545 KYGKVRVAELLLERDAHPNAAGK-NGLTPLHVAVHHNNLDIVKLLLPR-GGSPHSPAWNG 602
Query: 669 NTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
TPLH+AA + R LL+ G +AE+ + + PL
Sbjct: 603 YTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 639
Score = 76.6 bits (187), Expect = 9e-14
Identities = 83/286 (29%), Positives = 118/286 (41%), Gaps = 47/286 (16%)
Query: 486 ENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGV-VNLTNHLHQTPLHLAVITGQTSVVS 544
+ G TPLH+A + +V + ++ + G VN T TPLH+A G +V
Sbjct: 204 KTGFTPLHIAAHYENLNVAQLLL-------NRGASVNFTPQNGITPLHIASRRGNVIMVR 256
Query: 545 FLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPV 604
LL GA + + +H A R G + LL GAP + GL P+
Sbjct: 257 LLLDRGAQIETKTKDELTPLHCAARNGH--VRISEILLDHGAP-----IQAKTKNGLSPI 309
Query: 605 HLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR 664
H+A + +C+ LL+ AE++ T LH+A + L+ K A N+R
Sbjct: 310 HMAAQGDHLDCVRLLLQYDAEIDDITLDH-LTPLHVAAHCGHHRVAKVLLDK-GAKPNSR 367
Query: 665 TFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDT 724
G TPLH+A + + LLLK GA I A E L PL
Sbjct: 368 ALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHV----------------- 410
Query: 725 RSSFRGHTPLDLTCSTKVKTLLL-----NAAQNTMEPPLTPPSPAG 765
+SF GH P+ VK LL N + +E PL + AG
Sbjct: 411 -ASFMGHLPI-------VKNLLQRGASPNVSNVKVETPLHMAARAG 448
Score = 73.9 bits (180), Expect = 6e-13
Identities = 64/227 (28%), Positives = 102/227 (44%), Gaps = 21/227 (9%)
Query: 480 LLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGV-VNLTNHLHQTPLHLAVITG 538
+L + G+T LH+A + GQ V+ ++V + G VN + TPL++A
Sbjct: 70 ILETTTKKGNTALHIAALAGQDEVVRELV-------NYGANVNAQSQKGFTPLYMAAQEN 122
Query: 539 QTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDF 598
VV FLL GA+ + G + + +AL+ G ++ L+ G +L +
Sbjct: 123 HLEVVKFLLENGANQNVATEDGFTPLAVALQQGH--ENVVAHLINYGTKGKVRLPAL--- 177
Query: 599 EGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLR 658
H+A R +L+ + + + G T LH+A E L V L+
Sbjct: 178 ------HIAARNDDTRTAAVLLQNDPNPDVLSKTGF-TPLHIAAHYENLN-VAQLLLNRG 229
Query: 659 ANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
A+VN G TPLH+A+ G + RLLL GA I + ++ L PL
Sbjct: 230 ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 276
Score = 53.5 bits (127), Expect = 9e-07
Identities = 57/214 (26%), Positives = 91/214 (42%), Gaps = 36/214 (16%)
Query: 520 VNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLR 579
+N N LHLA G +V LL + G++A+H+A A AG E++R
Sbjct: 38 INTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIA--ALAGQDEVVR 95
Query: 580 ALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALH 639
L+ GA Q +G P+++A + E + L+++GA + + G T L
Sbjct: 96 ELVNYGANVNAQ-----SQKGFTPLYMAAQENHLEVVKFLLENGAN-QNVATEDGFTPLA 149
Query: 640 LATEMEELGLVTHLVT-----KLR--------ANVNARTFA---------------GNTP 671
+A + +V HL+ K+R N + RT A G TP
Sbjct: 150 VALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTP 209
Query: 672 LHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
LH+AA + +LLL GA ++ + + PL
Sbjct: 210 LHIAAHYENLNVAQLLLNRGASVNFTPQNGITPL 243
Score = 50.4 bits (119), Expect = 7e-06
Identities = 48/149 (32%), Positives = 71/149 (47%), Gaps = 28/149 (18%)
Query: 458 ARALLDYGVTADARA--------LLAGQRH-----LLTAQDENGD-------TPLHLAII 497
AR+LL YG +A+A + L A + H LL ++ NG+ TPLHL
Sbjct: 618 ARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQ 677
Query: 498 HGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLD 557
G V + V + H +V+ T + TPLH+A G +V FLL+ AD
Sbjct: 678 EGHVPVAD--VLIKHGV----MVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 731
Query: 558 RHGDSAMHLALRAGAGAPELLRALLQSGA 586
+ G S +H A A G +++ LL++GA
Sbjct: 732 KLGYSPLHQA--AQQGHTDIVTLLLKNGA 758
Score = 48.5 bits (114), Expect = 3e-05
Identities = 34/114 (29%), Positives = 53/114 (46%), Gaps = 19/114 (16%)
Query: 458 ARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDL 517
A L+ +GV DA + G TPLH+A +G +++ +++ H D
Sbjct: 684 ADVLIKHGVMVDATTRM-------------GYTPLHVASHYGNIKLVK---FLLQHQAD- 726
Query: 518 GVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAG 571
VN L +PLH A G T +V+ LL+ GA P + G + + +A R G
Sbjct: 727 --VNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLG 778
>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
Length = 1719
Score = 90.1 bits (222), Expect = 8e-18
Identities = 76/242 (31%), Positives = 112/242 (46%), Gaps = 16/242 (6%)
Query: 464 YGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLT 523
YG A LL H A +NG TPLH+A+ H +++ ++ G +
Sbjct: 546 YGKVRVAELLLERDAHP-NAAGKNGLTPLHVAVHHNNLDIVKLLL------PRGGSPHSP 598
Query: 524 NHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQ 583
TPLH+A Q V LL+ G G + +HLA A G E++ LL
Sbjct: 599 AWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLA--AQEGHAEMVALLLS 656
Query: 584 SGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATE 643
A ++ + GL P+HL + D+L+ G V+AT R G T LH+A+
Sbjct: 657 KQANG-----NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMG-YTPLHVASH 710
Query: 644 MEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLC 703
+ LV L+ +A+VNA+T G +PLH AA G+ + LLLK GA + + +
Sbjct: 711 YGNIKLVKFLLQH-QADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Query: 704 PL 705
PL
Sbjct: 770 PL 771
Score = 83.2 bits (204), Expect = 1e-15
Identities = 66/217 (30%), Positives = 103/217 (47%), Gaps = 15/217 (6%)
Query: 489 DTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLR 548
+TPLH+A G T V + ++ Q+ VN QTPLH A G T++V LL
Sbjct: 438 ETPLHMAARAGHTEVAKYLL------QNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE 491
Query: 549 VGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAV 608
A+P L G + +H+A R G E + ALL+ A +G P+H+A
Sbjct: 492 NNANPNLATTAGHTPLHIAAR--EGHVETVLALLEKEASQACMTK-----KGFTPLHVAA 544
Query: 609 RARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAG 668
+ +LL++ A A + G T LH+A L +V L+ + + ++ + G
Sbjct: 545 KYGKVRVAELLLERDAHPNAAGK-NGLTPLHVAVHHNNLDIVKLLLPR-GGSPHSPAWNG 602
Query: 669 NTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
TPLH+AA + R LL+ G +AE+ + + PL
Sbjct: 603 YTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 639
Score = 76.6 bits (187), Expect = 9e-14
Identities = 83/286 (29%), Positives = 118/286 (41%), Gaps = 47/286 (16%)
Query: 486 ENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGV-VNLTNHLHQTPLHLAVITGQTSVVS 544
+ G TPLH+A + +V + ++ + G VN T TPLH+A G +V
Sbjct: 204 KTGFTPLHIAAHYENLNVAQLLL-------NRGASVNFTPQNGITPLHIASRRGNVIMVR 256
Query: 545 FLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPV 604
LL GA + + +H A R G + LL GAP + GL P+
Sbjct: 257 LLLDRGAQIETKTKDELTPLHCAARNGH--VRISEILLDHGAP-----IQAKTKNGLSPI 309
Query: 605 HLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR 664
H+A + +C+ LL+ AE++ T LH+A + L+ K A N+R
Sbjct: 310 HMAAQGDHLDCVRLLLQYDAEIDDITLDH-LTPLHVAAHCGHHRVAKVLLDK-GAKPNSR 367
Query: 665 TFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDT 724
G TPLH+A + + LLLK GA I A E L PL
Sbjct: 368 ALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHV----------------- 410
Query: 725 RSSFRGHTPLDLTCSTKVKTLLL-----NAAQNTMEPPLTPPSPAG 765
+SF GH P+ VK LL N + +E PL + AG
Sbjct: 411 -ASFMGHLPI-------VKNLLQRGASPNVSNVKVETPLHMAARAG 448
Score = 73.9 bits (180), Expect = 6e-13
Identities = 64/227 (28%), Positives = 102/227 (44%), Gaps = 21/227 (9%)
Query: 480 LLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGV-VNLTNHLHQTPLHLAVITG 538
+L + G+T LH+A + GQ V+ ++V + G VN + TPL++A
Sbjct: 70 ILETTTKKGNTALHIAALAGQDEVVRELV-------NYGANVNAQSQKGFTPLYMAAQEN 122
Query: 539 QTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDF 598
VV FLL GA+ + G + + +AL+ G ++ L+ G +L +
Sbjct: 123 HLEVVKFLLENGANQNVATEDGFTPLAVALQQGH--ENVVAHLINYGTKGKVRLPAL--- 177
Query: 599 EGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLR 658
H+A R +L+ + + + G T LH+A E L V L+
Sbjct: 178 ------HIAARNDDTRTAAVLLQNDPNPDVLSKTGF-TPLHIAAHYENLN-VAQLLLNRG 229
Query: 659 ANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
A+VN G TPLH+A+ G + RLLL GA I + ++ L PL
Sbjct: 230 ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 276
Score = 53.5 bits (127), Expect = 9e-07
Identities = 57/214 (26%), Positives = 91/214 (42%), Gaps = 36/214 (16%)
Query: 520 VNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLR 579
+N N LHLA G +V LL + G++A+H+A A AG E++R
Sbjct: 38 INTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIA--ALAGQDEVVR 95
Query: 580 ALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALH 639
L+ GA Q +G P+++A + E + L+++GA + + G T L
Sbjct: 96 ELVNYGANVNAQ-----SQKGFTPLYMAAQENHLEVVKFLLENGAN-QNVATEDGFTPLA 149
Query: 640 LATEMEELGLVTHLVT-----KLR--------ANVNARTFA---------------GNTP 671
+A + +V HL+ K+R N + RT A G TP
Sbjct: 150 VALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTP 209
Query: 672 LHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
LH+AA + +LLL GA ++ + + PL
Sbjct: 210 LHIAAHYENLNVAQLLLNRGASVNFTPQNGITPL 243
Score = 50.4 bits (119), Expect = 7e-06
Identities = 48/149 (32%), Positives = 71/149 (47%), Gaps = 28/149 (18%)
Query: 458 ARALLDYGVTADARA--------LLAGQRH-----LLTAQDENGD-------TPLHLAII 497
AR+LL YG +A+A + L A + H LL ++ NG+ TPLHL
Sbjct: 618 ARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQ 677
Query: 498 HGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLD 557
G V + V + H +V+ T + TPLH+A G +V FLL+ AD
Sbjct: 678 EGHVPVAD--VLIKHGV----MVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 731
Query: 558 RHGDSAMHLALRAGAGAPELLRALLQSGA 586
+ G S +H A A G +++ LL++GA
Sbjct: 732 KLGYSPLHQA--AQQGHTDIVTLLLKNGA 758
Score = 48.5 bits (114), Expect = 3e-05
Identities = 34/114 (29%), Positives = 53/114 (46%), Gaps = 19/114 (16%)
Query: 458 ARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDL 517
A L+ +GV DA + G TPLH+A +G +++ +++ H D
Sbjct: 684 ADVLIKHGVMVDATTRM-------------GYTPLHVASHYGNIKLVK---FLLQHQAD- 726
Query: 518 GVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAG 571
VN L +PLH A G T +V+ LL+ GA P + G + + +A R G
Sbjct: 727 --VNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLG 778
>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
Length = 1856
Score = 90.1 bits (222), Expect = 8e-18
Identities = 76/242 (31%), Positives = 112/242 (46%), Gaps = 16/242 (6%)
Query: 464 YGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLT 523
YG A LL H A +NG TPLH+A+ H +++ ++ G +
Sbjct: 546 YGKVRVAELLLERDAHP-NAAGKNGLTPLHVAVHHNNLDIVKLLL------PRGGSPHSP 598
Query: 524 NHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQ 583
TPLH+A Q V LL+ G G + +HLA A G E++ LL
Sbjct: 599 AWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLA--AQEGHAEMVALLLS 656
Query: 584 SGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATE 643
A ++ + GL P+HL + D+L+ G V+AT R G T LH+A+
Sbjct: 657 KQANG-----NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMG-YTPLHVASH 710
Query: 644 MEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLC 703
+ LV L+ +A+VNA+T G +PLH AA G+ + LLLK GA + + +
Sbjct: 711 YGNIKLVKFLLQH-QADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTT 769
Query: 704 PL 705
PL
Sbjct: 770 PL 771
Score = 83.2 bits (204), Expect = 1e-15
Identities = 66/217 (30%), Positives = 103/217 (47%), Gaps = 15/217 (6%)
Query: 489 DTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLR 548
+TPLH+A G T V + ++ Q+ VN QTPLH A G T++V LL
Sbjct: 438 ETPLHMAARAGHTEVAKYLL------QNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE 491
Query: 549 VGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAV 608
A+P L G + +H+A R G E + ALL+ A +G P+H+A
Sbjct: 492 NNANPNLATTAGHTPLHIAAR--EGHVETVLALLEKEASQACMTK-----KGFTPLHVAA 544
Query: 609 RARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAG 668
+ +LL++ A A + G T LH+A L +V L+ + + ++ + G
Sbjct: 545 KYGKVRVAELLLERDAHPNAAGK-NGLTPLHVAVHHNNLDIVKLLLPR-GGSPHSPAWNG 602
Query: 669 NTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
TPLH+AA + R LL+ G +AE+ + + PL
Sbjct: 603 YTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 639
Score = 76.6 bits (187), Expect = 9e-14
Identities = 83/286 (29%), Positives = 118/286 (41%), Gaps = 47/286 (16%)
Query: 486 ENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGV-VNLTNHLHQTPLHLAVITGQTSVVS 544
+ G TPLH+A + +V + ++ + G VN T TPLH+A G +V
Sbjct: 204 KTGFTPLHIAAHYENLNVAQLLL-------NRGASVNFTPQNGITPLHIASRRGNVIMVR 256
Query: 545 FLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPV 604
LL GA + + +H A R G + LL GAP + GL P+
Sbjct: 257 LLLDRGAQIETKTKDELTPLHCAARNGH--VRISEILLDHGAP-----IQAKTKNGLSPI 309
Query: 605 HLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR 664
H+A + +C+ LL+ AE++ T LH+A + L+ K A N+R
Sbjct: 310 HMAAQGDHLDCVRLLLQYDAEIDDITLDH-LTPLHVAAHCGHHRVAKVLLDK-GAKPNSR 367
Query: 665 TFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDT 724
G TPLH+A + + LLLK GA I A E L PL
Sbjct: 368 ALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHV----------------- 410
Query: 725 RSSFRGHTPLDLTCSTKVKTLLL-----NAAQNTMEPPLTPPSPAG 765
+SF GH P+ VK LL N + +E PL + AG
Sbjct: 411 -ASFMGHLPI-------VKNLLQRGASPNVSNVKVETPLHMAARAG 448
Score = 73.9 bits (180), Expect = 6e-13
Identities = 64/227 (28%), Positives = 102/227 (44%), Gaps = 21/227 (9%)
Query: 480 LLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGV-VNLTNHLHQTPLHLAVITG 538
+L + G+T LH+A + GQ V+ ++V + G VN + TPL++A
Sbjct: 70 ILETTTKKGNTALHIAALAGQDEVVRELV-------NYGANVNAQSQKGFTPLYMAAQEN 122
Query: 539 QTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDF 598
VV FLL GA+ + G + + +AL+ G ++ L+ G +L +
Sbjct: 123 HLEVVKFLLENGANQNVATEDGFTPLAVALQQGH--ENVVAHLINYGTKGKVRLPAL--- 177
Query: 599 EGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLR 658
H+A R +L+ + + + G T LH+A E L V L+
Sbjct: 178 ------HIAARNDDTRTAAVLLQNDPNPDVLSKTGF-TPLHIAAHYENLN-VAQLLLNRG 229
Query: 659 ANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
A+VN G TPLH+A+ G + RLLL GA I + ++ L PL
Sbjct: 230 ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 276
Score = 53.5 bits (127), Expect = 9e-07
Identities = 57/214 (26%), Positives = 91/214 (42%), Gaps = 36/214 (16%)
Query: 520 VNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLR 579
+N N LHLA G +V LL + G++A+H+A A AG E++R
Sbjct: 38 INTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIA--ALAGQDEVVR 95
Query: 580 ALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALH 639
L+ GA Q +G P+++A + E + L+++GA + + G T L
Sbjct: 96 ELVNYGANVNAQ-----SQKGFTPLYMAAQENHLEVVKFLLENGAN-QNVATEDGFTPLA 149
Query: 640 LATEMEELGLVTHLVT-----KLR--------ANVNARTFA---------------GNTP 671
+A + +V HL+ K+R N + RT A G TP
Sbjct: 150 VALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTP 209
Query: 672 LHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
LH+AA + +LLL GA ++ + + PL
Sbjct: 210 LHIAAHYENLNVAQLLLNRGASVNFTPQNGITPL 243
Score = 50.4 bits (119), Expect = 7e-06
Identities = 48/149 (32%), Positives = 71/149 (47%), Gaps = 28/149 (18%)
Query: 458 ARALLDYGVTADARA--------LLAGQRH-----LLTAQDENGD-------TPLHLAII 497
AR+LL YG +A+A + L A + H LL ++ NG+ TPLHL
Sbjct: 618 ARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQ 677
Query: 498 HGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLD 557
G V + V + H +V+ T + TPLH+A G +V FLL+ AD
Sbjct: 678 EGHVPVAD--VLIKHGV----MVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKT 731
Query: 558 RHGDSAMHLALRAGAGAPELLRALLQSGA 586
+ G S +H A A G +++ LL++GA
Sbjct: 732 KLGYSPLHQA--AQQGHTDIVTLLLKNGA 758
Score = 48.5 bits (114), Expect = 3e-05
Identities = 34/114 (29%), Positives = 53/114 (46%), Gaps = 19/114 (16%)
Query: 458 ARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDL 517
A L+ +GV DA + G TPLH+A +G +++ +++ H D
Sbjct: 684 ADVLIKHGVMVDATTRM-------------GYTPLHVASHYGNIKLVK---FLLQHQAD- 726
Query: 518 GVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAG 571
VN L +PLH A G T +V+ LL+ GA P + G + + +A R G
Sbjct: 727 --VNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLG 778
>gi|30425444 ankyrin repeat and kinase domain containing 1 [Homo
sapiens]
Length = 765
Score = 89.7 bits (221), Expect = 1e-17
Identities = 91/302 (30%), Positives = 132/302 (43%), Gaps = 68/302 (22%)
Query: 457 SARALLDYGVTADARAL-------LAGQ-------RHLLTAQ------DENGDTPLHLAI 496
+AR LLD+G DA+ LA Q R L++ Q + G TPLH+A
Sbjct: 443 TARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAA 502
Query: 497 IHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALL 556
G S+++ + +Q + +L +TPLHLAV G+ + LL+ GA P L
Sbjct: 503 YFGHVSLVKLLT-----SQGAELDAQQRNL-RTPLHLAVERGKVRAIQHLLKSGAVPDAL 556
Query: 557 DRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECL 616
D+ G +H A A G + + LL+ GA L +P +G P+HLA E +
Sbjct: 557 DQSGYGPLHTA--AARGKYLICKMLLRYGAS-----LELPTHQGWTPLHLAAYKGHLEII 609
Query: 617 DLLVDS---------------------------------GAEVEATERQGGRTALHLATE 643
LL +S GA+ A E Q G T LHLA +
Sbjct: 610 HLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAE-QSGWTPLHLAVQ 668
Query: 644 MEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLC 703
V +L+ ANV+AR G TP HLAA G + ++L++AGA + ++
Sbjct: 669 RSTFLSVINLLEH-HANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCT 727
Query: 704 PL 705
PL
Sbjct: 728 PL 729
Score = 75.1 bits (183), Expect = 3e-13
Identities = 60/177 (33%), Positives = 82/177 (46%), Gaps = 9/177 (5%)
Query: 529 TPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPA 588
TPLH V G V LL D G + + +A A P+L LL GA A
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIA--AQDQQPDLCALLLAHGADA 421
Query: 589 VPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELG 648
+ D +G P+H A + LL+D GA V+A ER+G T LHLA +
Sbjct: 422 -----NRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGW-TPLHLAAQ-NNFE 474
Query: 649 LVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 705
V L+ +A+ N G TPLH+AA G+ +L +LL GA++ A+ PL
Sbjct: 475 NVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPL 531
Score = 66.2 bits (160), Expect = 1e-10
Identities = 57/184 (30%), Positives = 87/184 (47%), Gaps = 17/184 (9%)
Query: 488 GDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLL 547
G TPLHLA G +I + + LG VN T PLHLA G+ +VVS LL
Sbjct: 593 GWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWT------PLHLAARHGEEAVVSALL 646
Query: 548 RVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLA 607
+ GADP ++ G + +HLA++ + LL+ A +H + G P HLA
Sbjct: 647 QCGADPNAAEQSGWTPLHLAVQRSTFLSVI--NLLEHHAN-----VHARNKVGWTPAHLA 699
Query: 608 VRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFA 667
+ L +LV++GA+++ + T L LA + G+++ L K + T
Sbjct: 700 ALKGNTAILKVLVEAGAQLDVQDGV-SCTPLQLALRSRKQGIMSFLEGK---EPSVATLG 755
Query: 668 GNTP 671
G+ P
Sbjct: 756 GSKP 759
>gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo
sapiens]
Length = 226
Score = 87.0 bits (214), Expect = 7e-17
Identities = 62/190 (32%), Positives = 94/190 (49%), Gaps = 9/190 (4%)
Query: 516 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 575
D + T+ +T LH A G T +V FLL++G D G S +H+A A AG
Sbjct: 29 DKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA--ASAGRD 86
Query: 576 ELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGR 635
E+++ALL GA ++ + G P+H A E +L++ GA +A +
Sbjct: 87 EIVKALLGKGAQ-----VNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA- 140
Query: 636 TALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIH 695
TA+H A L ++ H++ +A+ N + GNTPLHLA +LL+ GA I+
Sbjct: 141 TAMHRAAAKGNLKMI-HILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIY 199
Query: 696 AENEEPLCPL 705
EN+E PL
Sbjct: 200 IENKEEKTPL 209
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,856,774
Number of Sequences: 37866
Number of extensions: 2243572
Number of successful extensions: 22028
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 470
Number of HSP's successfully gapped in prelim test: 330
Number of HSP's that attempted gapping in prelim test: 11440
Number of HSP's gapped (non-prelim): 4732
length of query: 899
length of database: 18,247,518
effective HSP length: 111
effective length of query: 788
effective length of database: 14,044,392
effective search space: 11066980896
effective search space used: 11066980896
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.