BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|116812577 LUC7-like 2 [Homo sapiens] (392 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|116812577 LUC7-like 2 [Homo sapiens] 770 0.0 gi|41393554 LUC7-like isoform b [Homo sapiens] 540 e-154 gi|8922297 LUC7-like isoform a [Homo sapiens] 523 e-148 gi|52426743 cisplatin resistance-associated overexpressed protei... 241 8e-64 gi|19923485 cisplatin resistance-associated overexpressed protei... 241 8e-64 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 99 9e-21 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 97 3e-20 gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 96 7e-20 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 95 1e-19 gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 92 6e-19 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 91 2e-18 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 91 2e-18 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 91 2e-18 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 89 5e-18 gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 89 5e-18 gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 87 3e-17 gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 85 1e-16 gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 85 1e-16 gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 85 1e-16 gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 85 1e-16 gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 85 1e-16 gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 84 2e-16 gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 82 6e-16 gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 82 6e-16 gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 82 8e-16 gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 81 2e-15 gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens] 79 7e-15 gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 78 2e-14 gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 78 2e-14 gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 77 2e-14 >gi|116812577 LUC7-like 2 [Homo sapiens] Length = 392 Score = 770 bits (1989), Expect = 0.0 Identities = 392/392 (100%), Positives = 392/392 (100%) Query: 1 MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECL 60 MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECL Sbjct: 1 MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECL 60 Query: 61 KVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVA 120 KVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVA Sbjct: 61 KVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVA 120 Query: 121 AKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPAS 180 AKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPAS Sbjct: 121 AKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPAS 180 Query: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRN 240 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRN Sbjct: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRN 240 Query: 241 QERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKR 300 QERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKR Sbjct: 241 QERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKR 300 Query: 301 HRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPR 360 HRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPR Sbjct: 301 HRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPR 360 Query: 361 DRDRKDKKRSYESANGRSEDRRSSEEREAGEI 392 DRDRKDKKRSYESANGRSEDRRSSEEREAGEI Sbjct: 361 DRDRKDKKRSYESANGRSEDRRSSEEREAGEI 392 >gi|41393554 LUC7-like isoform b [Homo sapiens] Length = 371 Score = 540 bits (1391), Expect = e-154 Identities = 286/392 (72%), Positives = 334/392 (85%), Gaps = 21/392 (5%) Query: 1 MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECL 60 MSAQAQMRA+LDQLMGT+RDGD TRQR+KF+DDRVCKSHLL+CCPHD+L+GTRMDLGEC Sbjct: 1 MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60 Query: 61 KVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVA 120 K+HDLALRADYEIASKE+D FFELDAMDHL+SFIA+CDRRTE+AKKRLAETQEEISAEV+ Sbjct: 61 KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120 Query: 121 AKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPAS 180 AKAE+VHELNEEIGKLLAK EQLGAEGNV+ESQK++ EVEK RAKK+EAEE YRNSMPAS Sbjct: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180 Query: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRN 240 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI+IREKL++L++ VAEKQEKRN Sbjct: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240 Query: 241 QERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKR 300 Q+RL+RREEREREER RRS S +++ +RSRSR+ RR RSRS SRER++ +RS+SR++ Sbjct: 241 QDRLRRREEREREERLS-RRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRH 299 Query: 301 HRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPR 360 RHRSR SRS SR H+R +SRDRS +K + S+ER ++ S + RS +R P Sbjct: 300 RRHRSR--SRSHSRGHRR---ASRDRS---AKYKFSRERASREE--SWESGRS--ERGPP 347 Query: 361 DRDRKDKKRSYESANGRSEDRRSSEEREAGEI 392 D ES+NG+ RR SEE+EAGEI Sbjct: 348 D-------WRLESSNGKMASRR-SEEKEAGEI 371 >gi|8922297 LUC7-like isoform a [Homo sapiens] Length = 325 Score = 523 bits (1346), Expect = e-148 Identities = 262/327 (80%), Positives = 300/327 (91%), Gaps = 6/327 (1%) Query: 1 MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECL 60 MSAQAQMRA+LDQLMGT+RDGD TRQR+KF+DDRVCKSHLL+CCPHD+L+GTRMDLGEC Sbjct: 1 MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60 Query: 61 KVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVA 120 K+HDLALRADYEIASKE+D FFELDAMDHL+SFIA+CDRRTE+AKKRLAETQEEISAEV+ Sbjct: 61 KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120 Query: 121 AKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPAS 180 AKAE+VHELNEEIGKLLAK EQLGAEGNV+ESQK++ EVEK RAKK+EAEE YRNSMPAS Sbjct: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180 Query: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRN 240 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI+IREKL++L++ VAEKQEKRN Sbjct: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240 Query: 241 QERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKR 300 Q+RL+RREEREREER RRS S +++ +RSRSR+ RR RSRS SRER++ +RS+SR++ Sbjct: 241 QDRLRRREEREREERLS-RRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRH 299 Query: 301 HRHRSRSSSRSRSRSHQRSRHSSRDRS 327 RHRSRS RS SR H+R +SRDRS Sbjct: 300 RRHRSRS--RSHSRGHRR---ASRDRS 321 >gi|52426743 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 241 bits (615), Expect = 8e-64 Identities = 144/391 (36%), Positives = 229/391 (58%), Gaps = 23/391 (5%) Query: 10 MLDQLMGTSRD--GDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLAL 67 +LD+LMG R+ D R +++ + VCK +L CP ++ + TR DLG C K+HD L Sbjct: 7 LLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENL 66 Query: 68 RADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKA---- 123 R YE +S+ +E D + +LQS +A+ +RR RLA +Q + S+ A Sbjct: 67 RKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNE 126 Query: 124 ERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQ 183 E++ L ++I LL ++E+LG+EG VEE+Q +M VE+ + ++RE +++ + + Q Sbjct: 127 EKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLK-EERELLRSTTSTIESFAAQ 185 Query: 184 QQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQER 243 ++++ VCEVC A+L + D R+ DH GK H+G+ +I+ +EELK + ++ E+ +++ Sbjct: 186 EKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDE 245 Query: 244 LKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRH 303 ++E++EREEREK R R + ++ R E R + R+ RER++R+RS+S RH Sbjct: 246 RLKKEKQEREEREK-EREREREERERKRRREEEEREKERARDRERRKRSRSRS-----RH 299 Query: 304 RSRSSSR--SRSRSHQRSRHSSRDRSRERSKRRS-------SKERFRDQD-LASCDRDRS 353 SR+S R SRSR H+RSR R RSR R +RRS K R R +D S RDR Sbjct: 300 SSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRK 359 Query: 354 SRDRSPRDRDRKDKKRSYESANGRSEDRRSS 384 S + RDR+ ++S E S+D++SS Sbjct: 360 SYKHRSKSRDREQDRKSKEKEKRGSDDKKSS 390 >gi|19923485 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 241 bits (615), Expect = 8e-64 Identities = 144/391 (36%), Positives = 229/391 (58%), Gaps = 23/391 (5%) Query: 10 MLDQLMGTSRD--GDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLAL 67 +LD+LMG R+ D R +++ + VCK +L CP ++ + TR DLG C K+HD L Sbjct: 7 LLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENL 66 Query: 68 RADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKA---- 123 R YE +S+ +E D + +LQS +A+ +RR RLA +Q + S+ A Sbjct: 67 RKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNE 126 Query: 124 ERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQ 183 E++ L ++I LL ++E+LG+EG VEE+Q +M VE+ + ++RE +++ + + Q Sbjct: 127 EKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLK-EERELLRSTTSTIESFAAQ 185 Query: 184 QQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQER 243 ++++ VCEVC A+L + D R+ DH GK H+G+ +I+ +EELK + ++ E+ +++ Sbjct: 186 EKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDE 245 Query: 244 LKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRH 303 ++E++EREEREK R R + ++ R E R + R+ RER++R+RS+S RH Sbjct: 246 RLKKEKQEREEREK-EREREREERERKRRREEEEREKERARDRERRKRSRSRS-----RH 299 Query: 304 RSRSSSR--SRSRSHQRSRHSSRDRSRERSKRRS-------SKERFRDQD-LASCDRDRS 353 SR+S R SRSR H+RSR R RSR R +RRS K R R +D S RDR Sbjct: 300 SSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRK 359 Query: 354 SRDRSPRDRDRKDKKRSYESANGRSEDRRSS 384 S + RDR+ ++S E S+D++SS Sbjct: 360 SYKHRSKSRDREQDRKSKEKEKRGSDDKKSS 390 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 98.6 bits (244), Expect = 9e-21 Identities = 82/251 (32%), Positives = 121/251 (48%), Gaps = 15/251 (5%) Query: 140 VEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGL 199 +E L E + E + + R KK+E +E P + L E +A + + Sbjct: 211 IEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINA-IEM 269 Query: 200 HDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREERERE-EREKL 258 ++ R L K F + +KLEE K K+EK QE K R ERERE ERE+ Sbjct: 270 EEDKRDLISREISK----FRDTHKKLEEEKG----KKEKERQEIEKERRERERERERERE 321 Query: 259 RRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQR 318 RR R + +R R +E R R R R+R R T+ + R+ R R R R R RS + Sbjct: 322 RREREREREREREREKEKERERERERDRDRDR-TKERDRD-RDRERDRDRDRERSSDRNK 379 Query: 319 SRHSSRDRSRERSKRRS-SKERFRDQDLASCDRDRSSRDRSPRDRDR-KDKKRSYESANG 376 R SR++SR+R + R +ER R+++ +R+R R+R+R KDKKR E Sbjct: 380 DRSRSREKSRDRERERERERERERERE-REREREREREREREREREREKDKKRDREEDEE 438 Query: 377 RSEDRRSSEER 387 + +RR E + Sbjct: 439 DAYERRKLERK 449 Score = 85.9 bits (211), Expect = 6e-17 Identities = 58/169 (34%), Positives = 84/169 (49%), Gaps = 11/169 (6%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRRE-EREREEREKLRRSRSHSKNPKRSRSREHRRHR 280 REK +E +R E++ R+++R K R+ +R+RE R RS +N RSRSRE R R Sbjct: 335 REKEKERER---ERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDR 391 Query: 281 SRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERF 340 R RER+R +R R R R R R R +R R + R RE + + + R Sbjct: 392 ERERERERER------EREREREREREREREREREREREREKDKKRDREEDEEDAYERRK 445 Query: 341 RDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREA 389 ++ L + R ++ R+RK K R YE R E+RR +EA Sbjct: 446 LERKLREKEAAYQERLKNWEIRERK-KTREYEKEAEREEERRREMAKEA 493 Score = 85.5 bits (210), Expect = 8e-17 Identities = 59/184 (32%), Positives = 91/184 (49%), Gaps = 14/184 (7%) Query: 213 KLHLGFIEIREKLEEL--KRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKR 270 K + IE+ E +L + + + + E K ++E+ER+E EK RR R +R Sbjct: 261 KEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRER------ER 314 Query: 271 SRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRER 330 R RE R R R RER+R + +R R R R R++ R R R RDR RER Sbjct: 315 ERERERER-REREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRER 373 Query: 331 SKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDR---KDKKRSYESANGRSEDRRSSEER 387 S R +K+R R ++ S DR+R R+R+R ++++R E R +R ++R Sbjct: 374 SSDR-NKDRSRSRE-KSRDREREREREREREREREREREREREREREREREREREKDKKR 431 Query: 388 EAGE 391 + E Sbjct: 432 DREE 435 Score = 58.2 bits (139), Expect = 1e-08 Identities = 59/217 (27%), Positives = 79/217 (36%), Gaps = 62/217 (28%) Query: 232 VAEKQEKRNQERLKRREEREREEREKLRR------------SRSHSKNPKRSR------- 272 V E+ E KRR++ + E L R S SH + K+ + Sbjct: 188 VTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRR 247 Query: 273 ------------------------------SREHRRHRSRSMSRERKRRTRSKSR---EK 299 SRE + R E ++ + K R EK Sbjct: 248 FPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEK 307 Query: 300 RHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRS-SKERFRDQDLASCDRDRSSRDRS 358 R R R R R R +R R R+R RE+ K R +ER RD+D +RDR Sbjct: 308 ERRERERERERERER-REREREREREREREKEKERERERERDRDRDRTK-ERDRDRDRER 365 Query: 359 PRDRDR-------KDKKRSYESANGRSEDRRSSEERE 388 RDRDR KD+ RS E + R +R ERE Sbjct: 366 DRDRDRERSSDRNKDRSRSREKSRDRERERERERERE 402 Score = 57.0 bits (136), Expect = 3e-08 Identities = 66/295 (22%), Positives = 119/295 (40%), Gaps = 33/295 (11%) Query: 111 TQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAE-GNVEESQKVMDEVEKARAKKREA 169 T+E+I+A + + ++ ++ EI K ++L E G E+ ++ +++ + R ++RE Sbjct: 260 TKEDINA-IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERER 318 Query: 170 EEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELK 229 E R ++++ + E D DR RE+ + Sbjct: 319 ERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRN 378 Query: 230 RVVAEKQEK-----RNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSM 284 + + +EK R +ER + RE ERE R R + +R R RE + R R Sbjct: 379 KDRSRSREKSRDRERERERERERERERERERE---REREREREREREREREKDKKRDREE 435 Query: 285 SRE---RKRRTRSKSREKRHRHRSRSSS-----RSRSRSHQRSRHSSRDRSRERSKR--- 333 E +R+ K REK ++ R + R ++R +++ +R RE +K Sbjct: 436 DEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKR 495 Query: 334 -----------RSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGR 377 R + +R L RDR ++ +RDRK +K E R Sbjct: 496 LKEFLEDYDDDRDDPKYYRGSALQKRLRDR-EKEMEADERDRKREKEELEEIRQR 549 Score = 53.5 bits (127), Expect = 3e-07 Identities = 70/335 (20%), Positives = 123/335 (36%), Gaps = 64/335 (19%) Query: 110 ETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREA 169 + ++ IS E++ + +L EE GK + +++ E E ++ + + R ++RE Sbjct: 272 DKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERER 331 Query: 170 E---EVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDR---RLADHFGGKLHLGFIEIRE 223 E E + + + R E D DR R +D + RE Sbjct: 332 EREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRS-----RE 386 Query: 224 KLEELKRVVAEKQEKRNQERLKRRE-EREREEREKLRRSRSHSKNPKRSRSR------EH 276 K + +R E++ +R +ER + RE ERERE + R R K+ KR R E Sbjct: 387 KSRDRER---EREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYER 443 Query: 277 RRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSS------------- 323 R+ + +E + R K+ E R R ++R + R +R R + Sbjct: 444 RKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDY 503 Query: 324 ------------------------------RDRSRERSKRRSSKERFRDQDLASCDRDRS 353 RDR RE+ + ++R + D + Sbjct: 504 DDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQ 563 Query: 354 SRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 ++ R + K+ ES E + E+RE Sbjct: 564 RMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKRE 598 Score = 37.7 bits (86), Expect = 0.018 Identities = 45/210 (21%), Positives = 78/210 (37%), Gaps = 17/210 (8%) Query: 98 DRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMD 157 +R E ++R E + E E +R E +EE K+E+ E +++ + Sbjct: 404 EREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKN 463 Query: 158 EVEKARAKKREAE-EVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHL 216 + R K RE E E R ++ R+ E Y D+DR ++ G Sbjct: 464 WEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDY----DDDRDDPKYYRGSALQ 519 Query: 217 GFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREH 276 + REK E ER ++RE+ E EE + + H + E Sbjct: 520 KRLRDREK------------EMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQ 567 Query: 277 RRHRSRSMSRERKRRTRSKSREKRHRHRSR 306 R R +++ + + EK+ + R Sbjct: 568 EAERRRQPQIKQEPESEEEEEEKQEKEEKR 597 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 97.1 bits (240), Expect = 3e-20 Identities = 83/318 (26%), Positives = 136/318 (42%), Gaps = 49/318 (15%) Query: 96 DCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKV 155 D +R+ + + R E + E + + + ER E K E +E E ++ Sbjct: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKEN-------KTEDRHSERGRERERER 216 Query: 156 MDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLH 215 E E R ++ + E R+ + +++K E S D +R Sbjct: 217 ETETETERKRQTDRE---RDRQRKTEREREKQAERERASERETERDKERE---------- 263 Query: 216 LGFIEIREKLEELKRVVAEKQEKRNQERLK-RREEREREEREKLRRSRSHSKNPKRSRSR 274 RE+ + R +K+ +R +R + RR ER+RE K R R + +R+R R Sbjct: 264 ------RERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317 Query: 275 EHRRHRSRSMSRERK-RRTRSKSREKRH-------RHRSRSSSRSRSRSHQRSRHSSRDR 326 E R R R R+R+ R R K RE++ R R+R + R R +R R R+R Sbjct: 318 ERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERER 377 Query: 327 SRERSKRRSSKERFRDQD-------LASCDRD--RSSRDRSPRDRDR-----KDKKRSYE 372 R+ ++ R +ER RD+D DRD R + + R++DR +++ R E Sbjct: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437 Query: 373 SANGRSEDRRSSEEREAG 390 GR DR +R+AG Sbjct: 438 KQKGRERDRERQTDRQAG 455 Score = 93.6 bits (231), Expect = 3e-19 Identities = 84/310 (27%), Positives = 151/310 (48%), Gaps = 37/310 (11%) Query: 96 DCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKV 155 + +R E + R + Q E + A+ ER + + E + + Q E E++++ Sbjct: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQ--KEREREKNRQE 187 Query: 156 MDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLH 215 E E+ R K+ + E+ R+S ++++ E + DR+ Sbjct: 188 RRERERQREKENKTED--RHSERGRERERERETETETERKRQTDRERDRQRKTE------ 239 Query: 216 LGFIEIREKLEELKRVVAEKQEKRNQERLKRRE-EREREEREKLRRSRSHSKNPKRS-RS 273 REK E +R +E++ +R++ER + R+ +R+R+ R+K R ++ K +R+ R Sbjct: 240 ----REREKQAERERA-SERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERD 294 Query: 274 REHRRHRSRSMSRERKR-RTRSKSREK---RHRHRSRSSSRSRSRSHQRSRHSSRDRSRE 329 RE R R R RER+R R R + RE+ R R R R + R R + +R R + RE Sbjct: 295 RETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354 Query: 330 RS-------KRRSSKERFRDQDLASCDRDR-SSRDRSPRDRDR---KDKKRSYESANGRS 378 R+ +R++ +ER R++ +RDR S+R+R R+RDR + K+R ++ R Sbjct: 355 RNRQTGREGRRQAERERERER-----ERDRQSAREREERERDRDRDRQKERERQTEKDRD 409 Query: 379 EDRRSSEERE 388 R + ++RE Sbjct: 410 GQRETEKQRE 419 Score = 92.4 bits (228), Expect = 6e-19 Identities = 76/298 (25%), Positives = 134/298 (44%), Gaps = 11/298 (3%) Query: 98 DRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMD 157 DR + +++ Q+E E + ER + + + + E + ++ Sbjct: 110 DRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQR 169 Query: 158 EVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLH-DNDRRLADHFGGKLHL 216 + E+ R K+RE E+ R Q++K E + G + +R K Sbjct: 170 QTERNRQKEREREK-NRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQT 228 Query: 217 GFIEIREKLEELKRVVAEKQEKRNQERLKRREERERE-EREKLRRSRSHSKNPKRSRSRE 275 R++ E +R ++E+ ++ +R +ERERE +R++ R R + + R R+ Sbjct: 229 DRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQ 288 Query: 276 HRRHRSRSMSRERKR-RTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERS--- 331 R R R R+R+R R R + RE R+R R R R R +R R + RDR +ER Sbjct: 289 RRTERDRETERKRERQRERERERE---RNRKRERERERERERERQRETERDREKERERKR 345 Query: 332 KRRSSKERFRDQDLASCDRDRSSRDRS-PRDRDRKDKKRSYESANGRSEDRRSSEERE 388 KR++ +R R++ R ++ R+R R+RDR+ + E R DR+ ER+ Sbjct: 346 KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ 403 Score = 87.0 bits (214), Expect = 3e-17 Identities = 55/180 (30%), Positives = 90/180 (50%), Gaps = 16/180 (8%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREERERE-EREKLR-RSRSHSKNPKRSRSREHRRH 279 R++ +E +R +++++ ++ R++ERERE ERE R R R +R R R+ + Sbjct: 99 RDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKE 158 Query: 280 RSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQR-----SRHSSRDRSRERS--- 331 R R RER+R+T +++R R ++R R R R ++ RHS R R RER Sbjct: 159 RERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERET 218 Query: 332 ------KRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSE 385 KR++ +ER R + ++ R+R+ +DK+R E R DRR E Sbjct: 219 ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKE 278 Score = 85.1 bits (209), Expect = 1e-16 Identities = 55/161 (34%), Positives = 83/161 (51%), Gaps = 8/161 (4%) Query: 234 EKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKR-RT 292 +++ R +ER +RRE+R+ E +R R K+ R R R R R R RER+ R Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112 Query: 293 RSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRR-SSKERFRDQD---LASC 348 R + REK R+R + R R +R R D RER ++R + KER R D Sbjct: 113 RDRQREK-ERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171 Query: 349 DRDR-SSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 +R+R R+R ++R++++R E N ++EDR S RE Sbjct: 172 ERNRQKEREREKNRQERRERERQREKEN-KTEDRHSERGRE 211 Score = 84.7 bits (208), Expect = 1e-16 Identities = 75/308 (24%), Positives = 125/308 (40%), Gaps = 24/308 (7%) Query: 98 DRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMD 157 DR E + R E + + E + E+ +E + + E+ G G ++ + Sbjct: 92 DRHRERQRDREKERERQTDRERDRQREKERNRQKERER---ETEREGERGRDRQTDGQRE 148 Query: 158 EVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217 + A+K + R + +QK R E + R + K Sbjct: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN----KTEDR 204 Query: 218 FIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREK-LRRSRSHSKNPKRSRSREH 276 E + E + E + KR +R + R+ + EREK R R+ + +R + RE Sbjct: 205 HSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERER 264 Query: 277 RRHRSRSMSRERKRRTRSKSREK-----RHRHRSRSSSRSRSRSHQRSRHSSRDRSRERS 331 R R R R +K R R R++ R R R R R R +R R+ R+R RER Sbjct: 265 ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERE 324 Query: 332 KRRS-SKERFRDQDLASCDRDRSSRDRSPRDRDRK-------DKKRSYESANGRSEDRRS 383 + R +E RD++ +R+R + ++ DR+R ++ E R DR+S Sbjct: 325 RERERQRETERDREK---ERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQS 381 Query: 384 SEEREAGE 391 + ERE E Sbjct: 382 AREREERE 389 Score = 79.3 bits (194), Expect = 5e-15 Identities = 54/184 (29%), Positives = 89/184 (48%), Gaps = 18/184 (9%) Query: 220 EIREKLEELKRVVAEKQEKRNQERLKRREERERE---EREKLR-----RSRSHSKNPKRS 271 E R + + +R K+E+R ++ R+ +R RE +REK R R R + +R+ Sbjct: 63 ERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERN 122 Query: 272 RSREHRRHRSRSMSRERKRRTRSKSREKRHR----HRSRSSSRSRSRSHQRSRHSSRDRS 327 R +E R R R R R+T + +R R R R + R R R +R+R R+R Sbjct: 123 RQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERERE 182 Query: 328 RERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRK---DKKRSYESANGRSEDRRSS 384 + R +RR ER R ++ + DR S R+R+R+ + +R ++ R R++ Sbjct: 183 KNRQERR---ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTE 239 Query: 385 EERE 388 ERE Sbjct: 240 RERE 243 Score = 76.6 bits (187), Expect = 3e-14 Identities = 42/167 (25%), Positives = 75/167 (44%), Gaps = 1/167 (0%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRS 281 R + +E +R ++Q +R +R KR RE++ K R R ++ ++ R R+ R R Sbjct: 56 RNRQKERERRREKRQTERETDR-KRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114 Query: 282 RSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFR 341 R +ER R+ + +R R R R +R R + ++R R+ + R + Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174 Query: 342 DQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 Q +++R R R R++++K S GR +R E E Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETE 221 Score = 71.2 bits (173), Expect = 1e-12 Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 8/152 (5%) Query: 245 KRREEREREEREKLRRSRSHSKNPKRSRSRE---HRRHRSRSMSRERKRRTRSKSREKRH 301 +R +E R L ++ + R R+R+ RR R RE R+ + + RH Sbjct: 29 RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88 Query: 302 RHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRS-SKERFRDQDL-ASCDRDRSSRDRSP 359 R R R R R R +R R + R+R R+R K R+ KER R+ + RDR + + Sbjct: 89 RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE 148 Query: 360 RDRDR---KDKKRSYESANGRSEDRRSSEERE 388 R+R R K+++R + R +R +ERE Sbjct: 149 RERQRDAEKERERQTDRERQRQTERNRQKERE 180 Score = 64.3 bits (155), Expect = 2e-10 Identities = 79/318 (24%), Positives = 130/318 (40%), Gaps = 50/318 (15%) Query: 96 DCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKV 155 D R+TE +++ AE + E ER E + + + + E+ + + Sbjct: 233 DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292 Query: 156 MD-EVEKARAKKREAE-EVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213 D E E+ R ++RE E E RN ++++ R + + +R Sbjct: 293 RDRETERKRERQRERERERERNRKRERERERERERERQ--------RETERD-------- 336 Query: 214 LHLGFIEIREKLEELKRV-VAEKQEKRNQE---RLKRREERERE-EREKLRRSRSHSKNP 268 REK E KR E +RN++ +R+ ERERE ERE+ R+S + Sbjct: 337 --------REKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREER 388 Query: 269 KRSRSREHRRHRSRSMSRER-------KRRTRSKSRE-KRHRHRSRSSSRSRSRSHQRSR 320 +R R R+ ++ R R ++R K+R R K RE +R R R R + + R R R Sbjct: 389 ERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRER 448 Query: 321 HSSRDRSRERSKRR---SSKERFRDQDLASCDRDRSSR----DRSPRDRDRKDKK----R 369 + R R+R + + R + D +R +R SP D + R Sbjct: 449 QTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGR 508 Query: 370 SYESANGRSEDRRSSEER 387 +++ GR RR E R Sbjct: 509 PAKASRGRVAGRRRWEPR 526 >gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo sapiens] Length = 375 Score = 95.5 bits (236), Expect = 7e-20 Identities = 59/155 (38%), Positives = 87/155 (56%), Gaps = 9/155 (5%) Query: 229 KRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRER 288 KR + R+ R + RE R R + ++SRS S+ K+SRSR R +SRS SRER Sbjct: 54 KRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER 113 Query: 289 KRRTRSKSREK-RHRHRSRSSSRSRSRSHQRSRHSSRDRSRERS-KRRSSKERFRDQDLA 346 KRR RS+SR + RHRHR+RS SR+RSRS R + + R RS R S FR ++ A Sbjct: 114 KRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTA 173 Query: 347 SCDR-------DRSSRDRSPRDRDRKDKKRSYESA 374 + +R+ + + R+++ +K++ E A Sbjct: 174 MDAQEALARRLERAKKLQEQREKEMVEKQKQQEIA 208 Score = 84.3 bits (207), Expect = 2e-16 Identities = 62/167 (37%), Positives = 86/167 (51%), Gaps = 9/167 (5%) Query: 234 EKQEKRNQERL---KRREEREREEREKLRRSRSHSKN---PKRSRSREHRRHRSRSMSRE 287 E + +ERL + E+R + + K R RSHS++ +R RSR R +SRS SRE Sbjct: 33 EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE 92 Query: 288 RKRRTRSKSRE-KRHRHRSRSSSRS-RSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDL 345 RK+ +RS+SRE K+ R RSR R RSRS RSRH R RSR R++ RS + R + Sbjct: 93 RKK-SRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKP 151 Query: 346 ASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI 392 R S P R R + E+ R E + +E+ E+ Sbjct: 152 RRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEM 198 Score = 80.9 bits (198), Expect = 2e-15 Identities = 57/148 (38%), Positives = 76/148 (51%), Gaps = 8/148 (5%) Query: 234 EKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTR 293 + +K E +E + RE+L S + KR + R+ R RS S SR R+RR R Sbjct: 19 KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKR-KERKSSRGRSHSRSRSRERRHR 77 Query: 294 SKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRS 353 S+SRE R + RSRS R +SRS R R SR RSRER +R S+ R R + R RS Sbjct: 78 SRSRE-RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR---HRTRS 133 Query: 354 SRDRSPRDRDRK---DKKRSYESANGRS 378 R RDRK +K R + + R+ Sbjct: 134 RSRTRSRSRDRKKRIEKPRRFSRSLSRT 161 Score = 77.4 bits (189), Expect = 2e-14 Identities = 49/139 (35%), Positives = 70/139 (50%), Gaps = 4/139 (2%) Query: 235 KQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKR-RTR 293 KQ +R++ + K ++ + EE S + S RH+ + R R +R Sbjct: 9 KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68 Query: 294 SKSREKRHRHRSRS--SSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRD 351 S+SRE+RHR RSR SRSRSR ++SR SR+R + RS+ R K R R + + Sbjct: 69 SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128 Query: 352 RSSRDRS-PRDRDRKDKKR 369 +R RS R R R KKR Sbjct: 129 HRTRSRSRTRSRSRDRKKR 147 Score = 70.5 bits (171), Expect = 3e-12 Identities = 50/140 (35%), Positives = 65/140 (46%), Gaps = 12/140 (8%) Query: 259 RRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRH------RSRSSSRSR 312 RR S K+ K+ +S EH + S + R+R S++ E RH+ R RS SRSR Sbjct: 12 RRHESKDKSSKKHKSEEHN-DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 70 Query: 313 S-----RSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDK 367 S RS R R SR RSRER K RS + S +R R R RS + + Sbjct: 71 SRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHR 130 Query: 368 KRSYESANGRSEDRRSSEER 387 RS RS DR+ E+ Sbjct: 131 TRSRSRTRSRSRDRKKRIEK 150 Score = 64.7 bits (156), Expect = 1e-10 Identities = 42/123 (34%), Positives = 64/123 (52%), Gaps = 2/123 (1%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPK-RSRSREHRRHR 280 RE+ + +K R++ER K R R RE ++ RSR + + RSRSR RHR Sbjct: 72 RERRHRSRSRERKKSRSRSRERKKSRS-RSRERKKSRSRSRERKRRIRSRSRSRSRHRHR 130 Query: 281 SRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERF 340 +RS SR R R K R ++ R SRS SR+ S R R+++ D ++R ++ Sbjct: 131 TRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKL 190 Query: 341 RDQ 343 ++Q Sbjct: 191 QEQ 193 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 95.1 bits (235), Expect = 1e-19 Identities = 95/391 (24%), Positives = 166/391 (42%), Gaps = 27/391 (6%) Query: 19 RDGDTTRQRIKFSDDRVCK-SHLLNCCPHDVL-SGTRMDLGECLKVHDLALRADYEIASK 76 RD TR R + D R + S + D S D HD R + K Sbjct: 459 RDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRK 518 Query: 77 EQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAE-RVHELNEE--I 133 E + E + + ++ + + RTE+ + E++ EI + ++ RV EL E+ Sbjct: 519 EDTYPEE--SRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSR 576 Query: 134 GKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQ-------- 185 G ++++ + N +S + + + R E R+ SSF+++ Sbjct: 577 GSRGSQIDSHSSNSNYHDSWETRSSYPE---RDRYPERDNRDQARDSSFERRHGERDRRD 633 Query: 186 -KLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERL 244 + R S ND D + + ++ R E + E++ R +ER Sbjct: 634 NRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRD-ERARERDRERERDRERERE 692 Query: 245 KRRE-EREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKR-----RTRSKSRE 298 + RE +RERE+ +L R R+ + +R + R+ R R R RER+R R + + RE Sbjct: 693 RERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERE 752 Query: 299 KRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRS 358 + R R R R R R +R R +R+R +ER ++R +++ + +D R+ DR+ Sbjct: 753 REERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRN 812 Query: 359 PRD-RDRKDKKRSYESANGRSEDRRSSEERE 388 PRD D + K+ Y + S + RE Sbjct: 813 PRDGHDERKSKKRYRNEGSPSPRQSPKRRRE 843 Score = 63.2 bits (152), Expect = 4e-10 Identities = 68/297 (22%), Positives = 111/297 (37%), Gaps = 57/297 (19%) Query: 98 DRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMD 157 DRR E A++R E + + E + ER E +E Sbjct: 670 DRRDERARERDRERERDRERERERERERDREREKE------------------------R 705 Query: 158 EVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217 E+E+ RA++RE E + HD +R Sbjct: 706 ELERERAREREREREKERDRERDRDRD---------------HDRERERERE-------- 742 Query: 218 FIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKN-PKRSRSREH 276 REK E +R E++ +R +ER +R ERERE + + R ++ + + R+ Sbjct: 743 --RDREKEREREREERERERERERER-ERERERERERARERDKERERQRDWEDKDKGRDD 799 Query: 277 RRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSS 336 RR + + +R R R+ + R+R+ S R +R HS + ++ Sbjct: 800 RREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNE 859 Query: 337 KERFRDQDLASCDRDRSSRDRSPR--DRDRKDKKRSYESANGRSEDRRSSEEREAGE 391 K R L+ R + SR SP DR+ + + + R E R EE+E E Sbjct: 860 KHRL----LSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKE 912 Score = 63.2 bits (152), Expect = 4e-10 Identities = 59/188 (31%), Positives = 93/188 (49%), Gaps = 15/188 (7%) Query: 200 HDNDRRLADHFGGK---LHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREERE 256 +D+ R D G+ LH G + REK + L+ + E++ + +Q +R E R Sbjct: 1211 NDSAHRSGDDQSGRKRVLHSGSRD-REKTKSLE-ITGERKSRIDQ---LKRGEPSRSTSS 1265 Query: 257 KLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREK--RHRHRSRSSSRSRSR 314 + SRSHS +RS R+ SRS S + + R + + R + R R R R +R R Sbjct: 1266 DRQDSRSHSS--RRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREW 1323 Query: 315 SHQRSRHSSRDRSRERSKRRS-SKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYES 373 + R+R R+R + R +ER + +DL +R+R D RDRDR D+ R++ES Sbjct: 1324 DRDADKDWPRNRDRDRLRERERERERDKRRDL-DRERERLISDSVERDRDR-DRDRTFES 1381 Query: 374 ANGRSEDR 381 + S R Sbjct: 1382 SQIESVKR 1389 Score = 60.5 bits (145), Expect = 3e-09 Identities = 49/155 (31%), Positives = 69/155 (44%), Gaps = 11/155 (7%) Query: 239 RNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSRE 298 R QER + +RERE + R R ++ + R R R R RER+R R Sbjct: 1298 RLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDR 1357 Query: 299 KRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRS 358 +R R S S R R R R+ SS+ S +R + + E R D + +SRD Sbjct: 1358 ERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHER-------DLESTSRDSL 1410 Query: 359 PRDRDRKDKKRSYESANGRSEDRRS--SEEREAGE 391 D++R DK S G E +S +E EAG+ Sbjct: 1411 ALDKERMDK--DLGSVQGFEETNKSERTESLEAGD 1443 Score = 55.8 bits (133), Expect = 6e-08 Identities = 94/340 (27%), Positives = 140/340 (41%), Gaps = 66/340 (19%) Query: 110 ETQEEISAEVAAKAERVHELN-----EEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARA 164 ET + S + VHEL+ ++I + L K+EQ E E K E R+ Sbjct: 145 ETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRS 204 Query: 165 K-------KREAEEVYRNSMPASSFQQQKLR-VCEVCSAYLGLHDNDRRLADHFGGKLHL 216 K ++ ++ R S P SS +K R V S L N + G Sbjct: 205 KLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTP 264 Query: 217 G-------FIEIREKLEELKRVVAEKQEKRNQERLKRRE-EREREEREKLRR-------- 260 I + +K +E +V +EK + + R+ ER+RE+R+K R Sbjct: 265 SPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHH 324 Query: 261 ----SRSHSKNPKRSRSREH-----RRHRSRSMSRERK-----RRTRS----------KS 296 SR HS + + S + RR R+ S S +R RR+ S + Sbjct: 325 SPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQR 384 Query: 297 REKRHRHRSRSSSRSR------SRSHQRSRHSSRDRSRERSKRR--SSKERFRDQDLASC 348 ++ RHRS + R S+SH R RH R+ +R + R S +ER +QD +S Sbjct: 385 KQSPPRHRSPMREKGRHDHERTSQSHDR-RHERREDTRGKRDREKDSREEREYEQDQSSS 443 Query: 349 DRDRSSRDRSPRD-RDRKDKKRSYESANGR-SEDRRSSEE 386 R DR PRD RDR+D + + + R S D R S E Sbjct: 444 RDHRD--DREPRDGRDRRDARDTRDRRELRDSRDMRDSRE 481 Score = 53.5 bits (127), Expect = 3e-07 Identities = 52/174 (29%), Positives = 70/174 (40%), Gaps = 25/174 (14%) Query: 223 EKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSR 282 EK+E + + Q + K +++ R +RSH+ RS S + HRS Sbjct: 1166 EKVETPHVTIEDAQHR------KPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSA-HRSG 1218 Query: 283 SMSRERKR--------RTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRR 334 RKR R ++KS E +SR R RS S R SR S RR Sbjct: 1219 DDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEP-SRSTSSDRQDSRSHSSRR 1277 Query: 335 SSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 SS E DR SR S RDR ++ YE R +RR + +RE Sbjct: 1278 SSPE---------SDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQRE 1322 Score = 53.1 bits (126), Expect = 4e-07 Identities = 43/152 (28%), Positives = 60/152 (39%), Gaps = 10/152 (6%) Query: 238 KRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSR 297 + + ER + +R E RE R R K+ + R E + +S SR+ + R Sbjct: 400 RHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYE----QDQSSSRDHR-----DDR 450 Query: 298 EKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDR 357 E R R + +R R R RD R R +KE +D S RDR Sbjct: 451 EPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDR 510 Query: 358 SPRDRDRKDKKRSYESAN-GRSEDRRSSEERE 388 RD RK+ ES + GR+ R S E Sbjct: 511 EGRDTHRKEDTYPEESRSYGRNHLREESSRTE 542 Score = 52.8 bits (125), Expect = 5e-07 Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 11/138 (7%) Query: 262 RSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRH 321 +S K S SR+ + +S ++ ERK R R + R S SRS S +RS Sbjct: 1221 QSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSP 1280 Query: 322 SSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRD-----------RKDKKRS 370 S + RS S++R +++D DR+R R R R+ +D+ R Sbjct: 1281 ESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRL 1340 Query: 371 YESANGRSEDRRSSEERE 388 E R D+R +RE Sbjct: 1341 RERERERERDKRRDLDRE 1358 Score = 50.8 bits (120), Expect = 2e-06 Identities = 47/170 (27%), Positives = 74/170 (43%), Gaps = 18/170 (10%) Query: 221 IREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHR 280 +REK ++ ++R++ R R +R+RE+ R R + ++ +S SR+HR R Sbjct: 395 MREKGRHDHERTSQSHDRRHERREDTRGKRDREKDS--REEREYEQD--QSSSRDHRDDR 450 Query: 281 SRSMSRERKRRTRSKSREKRHRHRSRSSSRSRS-RSHQRSRHSSRDRSRERSKRRSSKER 339 R+ RR +R++R SR SR R + R SRD RS R Sbjct: 451 EPRDGRD--RRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRD----- 503 Query: 340 FRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREA 389 A RDR RD ++ ++ RSY + R E R+ E+ Sbjct: 504 ------AHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNES 547 Score = 48.9 bits (115), Expect = 8e-06 Identities = 55/192 (28%), Positives = 83/192 (43%), Gaps = 39/192 (20%) Query: 234 EKQEKRNQERLKRREEREREE------REKLRRSRSHSKNPKRSRS-REHRRHRSRSMSR 286 +++ + ++R R+ R+R E R R +S++ K SR R+ R R R Sbjct: 449 DREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYR 508 Query: 287 ERKRRT----------------RSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSR-- 328 +R+ R R+ RE+ R R+ SR+ SRS R+ R R R Sbjct: 509 DREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVP 568 Query: 329 ---ERSKRRSSKERFRDQDLASCDRD----RSS---RDRSPRDRDRKDKKR--SYESANG 376 E+ R S + S D RSS RDR P +RD +D+ R S+E +G Sbjct: 569 ELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYP-ERDNRDQARDSSFERRHG 627 Query: 377 RSEDRRSSEERE 388 DRR + ER+ Sbjct: 628 -ERDRRDNRERD 638 Score = 41.6 bits (96), Expect = 0.001 Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 17/148 (11%) Query: 258 LRRSRS----HS-KNPKRSRSREHRRHRSRSMSR-ERKRRTRSKSREKRHRH-----RSR 306 LRRS S HS +P+R +S R R R + +R ++S R R R R Sbjct: 367 LRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDR 426 Query: 307 SSSRSRSRSHQRSRHSSRDRSRERSKR----RSSKERFRDQDLASCDRD-RSSRDRSPRD 361 R +++ + SSRD +R R R RD+ RD R SR+ Sbjct: 427 EKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYS 486 Query: 362 RDRKDKKRSYESANGR-SEDRRSSEERE 388 RD K+ + +S + R + D R E R+ Sbjct: 487 RDTKESRDPRDSRSTRDAHDYRDREGRD 514 Score = 38.1 bits (87), Expect = 0.014 Identities = 37/174 (21%), Positives = 71/174 (40%), Gaps = 9/174 (5%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRRE---EREREEREKLRRSRSHSKNPKRSRSREHRR 278 R K E+ K E + ++ LK + +++RE+ E L SR +++ E R Sbjct: 888 RWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRE 947 Query: 279 HRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSR--SRSHQRSRHSSRDRSRERSKRRSS 336 R+ +K+ K K+ + R + S S + +++S + Sbjct: 948 TSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKR 1007 Query: 337 KERFRDQDLASCDR-DRSSRDRSPRDRDRKDKKRSYESANGRS---EDRRSSEE 386 K+ D D++ + +S + R PR K+ E NG++ ED + E+ Sbjct: 1008 KKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKED 1061 Score = 36.2 bits (82), Expect = 0.052 Identities = 31/168 (18%), Positives = 70/168 (41%), Gaps = 6/168 (3%) Query: 223 EKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRH-RS 281 E+ E +R ++ +++ K+RE+ E E ++R + R R H + Sbjct: 897 ERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDEN 956 Query: 282 RSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKER-F 340 + ++ +K+ + K + R + S + + +S E+ +++S + Sbjct: 957 KKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDI 1016 Query: 341 RDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 D++ A +S + R PR K+ E NG++ S+++E Sbjct: 1017 SDEEAA----QQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKE 1060 Score = 35.4 bits (80), Expect = 0.089 Identities = 35/133 (26%), Positives = 60/133 (45%), Gaps = 7/133 (5%) Query: 263 SHSKNPKRSRSREHRR-HRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRH 321 +++ N + HR+ HR+R E T ++ ++ + RSSS +RS+ RS Sbjct: 1144 TNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSN-RSHT 1202 Query: 322 SSRDR--SRERSKRRSSKERFRDQDLASCDRDR---SSRDRSPRDRDRKDKKRSYESANG 376 S R R S + + R + R + L S RDR S + + + R D+ + E + Sbjct: 1203 SGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRS 1262 Query: 377 RSEDRRSSEEREA 389 S DR+ S + Sbjct: 1263 TSSDRQDSRSHSS 1275 Score = 32.3 bits (72), Expect = 0.76 Identities = 34/156 (21%), Positives = 63/156 (40%), Gaps = 15/156 (9%) Query: 241 QERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKR 300 +ER+K + R+ + E +R+ S +P R S RHR + + K RT E Sbjct: 86 RERMKNK--RQDVDTEPQKRNTEESSSPVRKES-SRGRHREKEDIKITKERTPESEEENV 142 Query: 301 HRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRR---------SSKERFRDQDLASCDRD 351 +R S + ++ S + R++ +R +E + S + Sbjct: 143 EWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVV 202 Query: 352 RSSRDRSP---RDRDRKDKKRSYESANGRSEDRRSS 384 RS SP + +K S +S++ +DR++S Sbjct: 203 RSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTS 238 >gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo sapiens] Length = 434 Score = 92.4 bits (228), Expect = 6e-19 Identities = 74/234 (31%), Positives = 111/234 (47%), Gaps = 24/234 (10%) Query: 150 EESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADH 209 E +K +E K R++ R E S SS + + H++ +D Sbjct: 49 ERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEE-----------HNDKEHSSDK 97 Query: 210 FGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPK 269 G+ L E E + K + + ++ R + R R R K RSRS + Sbjct: 98 --GRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKS 155 Query: 270 RSRSREHRRHRSRSMSRERKRRTRSKSREK-RHRHRSRSSSRSRSRSHQRSRHSSRDRSR 328 RSRSRE R +SRS SRERKRR RS+SR + RHRHR+RS SR+RSRS R + + R Sbjct: 156 RSRSRE--RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRF 213 Query: 329 ERS-KRRSSKERFRDQDLASCDR-------DRSSRDRSPRDRDRKDKKRSYESA 374 RS R S FR ++ A + +R+ + + R+++ +K++ E A Sbjct: 214 SRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIA 267 Score = 85.1 bits (209), Expect = 1e-16 Identities = 63/172 (36%), Positives = 86/172 (50%), Gaps = 14/172 (8%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRS 281 RE+L + E + KR + + R R R + RR RS S+ K+SRSR R +S Sbjct: 99 RERLNSSEN--GEDRHKRKERKSSRGRSHSRS-RSRERRHRSRSRERKKSRSRSRERKKS 155 Query: 282 RSMSRERKR-RTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERF 340 RS R R+R ++RS+SRE++ R RSRS SRSR R RSR +R RSR+R KR RF Sbjct: 156 RS--RSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRF 213 Query: 341 RDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI 392 R S P R R + E+ R E + +E+ E+ Sbjct: 214 --------SRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEM 257 Score = 80.9 bits (198), Expect = 2e-15 Identities = 56/148 (37%), Positives = 77/148 (52%), Gaps = 8/148 (5%) Query: 234 EKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTR 293 + +K E +E + RE+L S + KR + R+ R RS S SR R+RR R Sbjct: 78 KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKR-KERKSSRGRSHSRSRSRERRHR 136 Query: 294 SKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRS 353 S+SRE++ + RSRS R +SRS R R SR RSRER +R S+ R R + R RS Sbjct: 137 SRSRERK-KSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR---HRTRS 192 Query: 354 SRDRSPRDRDRK---DKKRSYESANGRS 378 R RDRK +K R + + R+ Sbjct: 193 RSRTRSRSRDRKKRIEKPRRFSRSLSRT 220 Score = 79.0 bits (193), Expect = 7e-15 Identities = 64/196 (32%), Positives = 83/196 (42%), Gaps = 45/196 (22%) Query: 237 EKRNQERLKRREERE-----REEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRE---- 287 EK + +R K++E+ E R + RSRS S+ KR E R+HRSRS S+E Sbjct: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRH 73 Query: 288 -------------------------RKRRTRSKSREKRHRH------RSRSSSRSRS--- 313 R+R S++ E RH+ R RS SRSRS Sbjct: 74 ESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 133 Query: 314 --RSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSY 371 RS R R SR RSRER K RS + S +R R R RS + + RS Sbjct: 134 RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSR 193 Query: 372 ESANGRSEDRRSSEER 387 RS DR+ E+ Sbjct: 194 SRTRSRSRDRKKRIEK 209 Score = 78.6 bits (192), Expect = 9e-15 Identities = 59/181 (32%), Positives = 86/181 (47%), Gaps = 22/181 (12%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREERE----KLRRSRSHSKNPKR--SRSRE 275 R+K +E V + ++ R RER+ + + RSRS SK +R S+ + Sbjct: 20 RDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKS 79 Query: 276 HRRHRS-------RSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSR-HSSRDRS 327 ++H+S S + R+R S++ E RH+ + R SSR RS S RSR R RS Sbjct: 80 SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRS 139 Query: 328 RERSKRRS-SKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEE 386 RER K RS S+ER + R RS + R R R+ K+R + RS R + Sbjct: 140 RERKKSRSRSRERKK-------SRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRS 192 Query: 387 R 387 R Sbjct: 193 R 193 Score = 78.6 bits (192), Expect = 9e-15 Identities = 54/164 (32%), Positives = 81/164 (49%), Gaps = 17/164 (10%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRS--------RSHSKNPKRSRS 273 R + E KR ++ + ++++ R + +E R E ++K + + HS + R R Sbjct: 44 RSRSRERKRK-SDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERL 102 Query: 274 REHRRHRSRSMSRERKR-----RTRSKSREKRHRHRSRS--SSRSRSRSHQRSRHSSRDR 326 R +ERK +RS+SRE+RHR RSR SRSRSR ++SR SR+R Sbjct: 103 NSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRER 162 Query: 327 SRERSKRRSSKERFRDQDLASCDRDRSSRDRS-PRDRDRKDKKR 369 + RS+ R K R R + + +R RS R R R KKR Sbjct: 163 KKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR 206 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 90.9 bits (224), Expect = 2e-18 Identities = 51/172 (29%), Positives = 94/172 (54%), Gaps = 6/172 (3%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRRE-EREREEREKLRRSRSHSKNPKRSRSREHRRHR 280 RE+ +E KR +K++K+ ++R + +E ER+R+EREK R+ R + KR + ++ R + Sbjct: 48 REREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERK 107 Query: 281 SRSMSRERKRRTRSKSRE---KRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSK 337 R RERK++ K RE K+ R R R R + R +R R R + + K+R + Sbjct: 108 QRG-RRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE 166 Query: 338 ERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREA 389 ER + ++ +R + R+R R +K++K+ R +DR++ + ++ Sbjct: 167 EREKKRERNRKER-KKERERKERRERKKERKKERRKKKERKKDRKTDRQTDS 217 Score = 88.2 bits (217), Expect = 1e-17 Identities = 53/171 (30%), Positives = 93/171 (54%), Gaps = 5/171 (2%) Query: 220 EIREKLEELKRVVAEKQEKRNQERLKRREERER-EEREKLRRSRSHSKNPKRSRSREHRR 278 E RE+ + + E++ +R ++ K+R++RER +ERE+ R+ R K K R +E R+ Sbjct: 39 ERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKER--EKQRKERREKERRK 96 Query: 279 HRSRSMSRERKRRTRSKSREKRHR-HRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSK 337 + RERK+R R + ++K+ R R R + + R R ++ R R + R+R K R + Sbjct: 97 RKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKR 156 Query: 338 ERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 ER R + + R+R R ++R+ K+R E R ++RR +ER+ Sbjct: 157 ERKRKKRKKEEREKKRERNRKERKKERERKERR-ERKKERKKERRKKKERK 206 Score = 87.4 bits (215), Expect = 2e-17 Identities = 53/170 (31%), Positives = 90/170 (52%), Gaps = 12/170 (7%) Query: 229 KRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRR---HRSRSMS 285 +R K+E+R +E+ KR E+ER+ RE+ ++ + K +R + RE +R + R Sbjct: 31 QRESERKKERREREKRKREREKERK-RERGKKEKKKRKKRERGKERERKRKEREKQRKER 89 Query: 286 RERKRRTRSKSREKRHR-HRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSK---ERFR 341 RE++RR R K ++KR R R R + + +R R + + R R+R KRR K ER R Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149 Query: 342 DQDLASCDRDRSSRDRSPRD----RDRKDKKRSYESANGRSEDRRSSEER 387 +++ +R R R + R+ R+RK++K+ E R + +ER Sbjct: 150 EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER 199 Score = 87.0 bits (214), Expect = 3e-17 Identities = 52/163 (31%), Positives = 85/163 (52%), Gaps = 10/163 (6%) Query: 235 KQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHR-----SRSMSRERK 289 +++K +ER KR+ ERE+E R++ R + K KR R +E R R R RE++ Sbjct: 35 ERKKERREREKRKREREKE-RKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93 Query: 290 RRTRSKSREKRHR-HRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSS---KERFRDQDL 345 RR R K ++KR R R R + + +R R + + R R+R KRR KER R+++ Sbjct: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153 Query: 346 ASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 +R R R + R++ R+ ++ + R E R +ER+ Sbjct: 154 GKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERK 196 Score = 81.6 bits (200), Expect = 1e-15 Identities = 47/150 (31%), Positives = 76/150 (50%), Gaps = 14/150 (9%) Query: 245 KRREEREREEREKLRRSRSHSKNPKRSRSREH---RRHRSRSMSRERKRRTRSKSREKRH 301 +R ER++E RE+ +R R K KR R ++ R+ R R RERKR+ R K R++R Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER- 89 Query: 302 RHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRD 361 R R + + ++ R + RER K++ KER R+ ++ R R R R Sbjct: 90 ----REKERRKRKKEKKKRERKQRGRRERKKKKERKERERE------NKQRRERKRKKRR 139 Query: 362 RDRKDKKRSYESANGRSEDRRSSEEREAGE 391 + ++ K+R E G+ E +R ++E E Sbjct: 140 KKKRRKERKREKERGKRERKRKKRKKEERE 169 Score = 80.1 bits (196), Expect = 3e-15 Identities = 47/128 (36%), Positives = 74/128 (57%), Gaps = 10/128 (7%) Query: 220 EIREKLEELKRVVAEKQEKRNQERLKRREEREREERE---KLRRSRSHSKNPKRSRSREH 276 E REK ++ +K+E++ + R +R++++ER+ERE K RR R K K+ R +E Sbjct: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKER 147 Query: 277 RRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSK-RRS 335 +R + R RERKR+ R K ++ R R+R + R +R R R+R +ER K RR Sbjct: 148 KREKERG-KRERKRKKRKKEEREKKRERNR-----KERKKERERKERRERKKERKKERRK 201 Query: 336 SKERFRDQ 343 KER +D+ Sbjct: 202 KKERKKDR 209 Score = 67.4 bits (163), Expect = 2e-11 Identities = 55/249 (22%), Positives = 102/249 (40%), Gaps = 47/249 (18%) Query: 94 IADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQ 153 + C ++ +R +E ++E K ER E E GK K + G +E + Sbjct: 19 MVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG--KERE 76 Query: 154 KVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213 + E EK R ++RE E R ++Q+ R Sbjct: 77 RKRKEREKQRKERREKERRKRKKEKKKRERKQRGR------------------------- 111 Query: 214 LHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRS 273 RE+ K++K +ER +R ++ RE + K RR + K KR + Sbjct: 112 --------RER----------KKKKERKER-ERENKQRRERKRKKRRKKKRRKERKREKE 152 Query: 274 REHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRER-SK 332 R R + + +E + + R ++R++R + R R R R + ++ R ++R ++R + Sbjct: 153 RGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTD 212 Query: 333 RRSSKERFR 341 R++ + FR Sbjct: 213 RQTDSQVFR 221 Score = 58.5 bits (140), Expect = 1e-08 Identities = 29/127 (22%), Positives = 62/127 (48%), Gaps = 4/127 (3%) Query: 261 SRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSR 320 S SH P R E ++ R R + ++ R + + RE+ + + + R R + +R R Sbjct: 21 SCSHISKPCTQRESERKKER-REREKRKREREKERKRERGKKEKKKRKKRERGKERERKR 79 Query: 321 HSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSED 380 ++R ++R +RR + R R ++ +R + R + ++RK+++R + R Sbjct: 80 ---KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK 136 Query: 381 RRSSEER 387 +R ++R Sbjct: 137 KRRKKKR 143 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 90.5 bits (223), Expect = 2e-18 Identities = 77/303 (25%), Positives = 139/303 (45%), Gaps = 30/303 (9%) Query: 99 RRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDE 158 + E KR+ E Q ISA + ++ + +E + G+ + + S++ + Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNE--RKGGRSRSHTRSKSRSSSKSHSRRKRSQ 330 Query: 159 VEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGF 218 + + ++ + S +++ + E + H D+R Sbjct: 331 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRK------------ 378 Query: 219 IEIREKLEELKRVVA---EKQEKRNQERLKRREEREREEREKLR---RSRSHSKNPKRSR 272 + REK++E +RV EK+ +R +ER K +E + ++R+K R R + K+ +R R Sbjct: 379 -DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 437 Query: 273 SREHRRHRSRSMSRER---KRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHS-SRDRSR 328 +EH + R + +E+ K R + +S+E + + SR+ RS+ SR S S R R Sbjct: 438 EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRER 497 Query: 329 ERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYE--SANGRSEDRRSSEE 386 R + RSS R + + +SSR SPR R++KDKKR E + R E RS+ Sbjct: 498 RRRRSRSSS---RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSM 554 Query: 387 REA 389 R++ Sbjct: 555 RKS 557 Score = 75.9 bits (185), Expect = 6e-14 Identities = 57/173 (32%), Positives = 92/173 (53%), Gaps = 8/173 (4%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRS 281 REK +E R E++ ++ E+ + +E+ + +++EK R + SK R ++ ++ R+ Sbjct: 425 REKDKEKDR---EREREKEHEKDRDKEKEKEQDKEK-EREKDRSKEIDEKRKKD-KKSRT 479 Query: 282 RSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRS-RERSKRRSSKERF 340 S RR+RS SRE+R R RSRSSSRS S R SSR S R R+K+ +E+ Sbjct: 480 PPRSYNASRRSRSSSRERR-RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 538 Query: 341 RDQDLASCDRDRS-SRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI 392 RD +R+RS S +S DRD K+K ++ E + + + E+ Sbjct: 539 RDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEV 591 Score = 55.1 bits (131), Expect = 1e-07 Identities = 47/187 (25%), Positives = 87/187 (46%), Gaps = 27/187 (14%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKL---------RRSRSHSKNPKRSR 272 R+K +E ++ +K+++R ++R K +E+ +++++ RRSRS S+ +R R Sbjct: 445 RDKEKEKEQ---DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR 501 Query: 273 SREH----------RRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHS 322 SR +R SRS S R R + K REK H S R RS S ++S + Sbjct: 502 SRSSSRSPRTSKTIKRKSSRSPS-PRSRNKKDKKREKERDHISERRERERSTSMRKSSND 560 Query: 323 SRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRR 382 + + S KE+ +++ S S++ +D R ++ + + N + + Sbjct: 561 RDGKEKLEKNSTSLKEKEHNKEPDS----SVSKEVDDKDAPRTEENKIQHNGNCQLNEEN 616 Query: 383 SSEEREA 389 S + EA Sbjct: 617 LSTKTEA 623 Score = 50.8 bits (120), Expect = 2e-06 Identities = 32/135 (23%), Positives = 54/135 (40%) Query: 257 KLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSH 316 K+ S + P + + M R R+ ++ + + +S RSRSH Sbjct: 252 KINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSH 311 Query: 317 QRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANG 376 RS+ S +S R KR SK R R + + + R +SP + K ++R + Sbjct: 312 TRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRS 371 Query: 377 RSEDRRSSEEREAGE 391 S D+R + E Sbjct: 372 HSRDKRKDTREKIKE 386 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 90.5 bits (223), Expect = 2e-18 Identities = 77/303 (25%), Positives = 139/303 (45%), Gaps = 30/303 (9%) Query: 99 RRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDE 158 + E KR+ E Q ISA + ++ + +E + G+ + + S++ + Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNE--RKGGRSRSHTRSKSRSSSKSHSRRKRSQ 214 Query: 159 VEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGF 218 + + ++ + S +++ + E + H D+R Sbjct: 215 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRK------------ 262 Query: 219 IEIREKLEELKRVVA---EKQEKRNQERLKRREEREREEREKLR---RSRSHSKNPKRSR 272 + REK++E +RV EK+ +R +ER K +E + ++R+K R R + K+ +R R Sbjct: 263 -DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 321 Query: 273 SREHRRHRSRSMSRER---KRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHS-SRDRSR 328 +EH + R + +E+ K R + +S+E + + SR+ RS+ SR S S R R Sbjct: 322 EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRER 381 Query: 329 ERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYE--SANGRSEDRRSSEE 386 R + RSS R + + +SSR SPR R++KDKKR E + R E RS+ Sbjct: 382 RRRRSRSSS---RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSM 438 Query: 387 REA 389 R++ Sbjct: 439 RKS 441 Score = 75.9 bits (185), Expect = 6e-14 Identities = 57/173 (32%), Positives = 92/173 (53%), Gaps = 8/173 (4%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRS 281 REK +E R E++ ++ E+ + +E+ + +++EK R + SK R ++ ++ R+ Sbjct: 309 REKDKEKDR---EREREKEHEKDRDKEKEKEQDKEK-EREKDRSKEIDEKRKKD-KKSRT 363 Query: 282 RSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRS-RERSKRRSSKERF 340 S RR+RS SRE+R R RSRSSSRS S R SSR S R R+K+ +E+ Sbjct: 364 PPRSYNASRRSRSSSRERR-RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 422 Query: 341 RDQDLASCDRDRS-SRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI 392 RD +R+RS S +S DRD K+K ++ E + + + E+ Sbjct: 423 RDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEV 475 Score = 55.1 bits (131), Expect = 1e-07 Identities = 47/187 (25%), Positives = 87/187 (46%), Gaps = 27/187 (14%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKL---------RRSRSHSKNPKRSR 272 R+K +E ++ +K+++R ++R K +E+ +++++ RRSRS S+ +R R Sbjct: 329 RDKEKEKEQ---DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR 385 Query: 273 SREH----------RRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHS 322 SR +R SRS S R R + K REK H S R RS S ++S + Sbjct: 386 SRSSSRSPRTSKTIKRKSSRSPS-PRSRNKKDKKREKERDHISERRERERSTSMRKSSND 444 Query: 323 SRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRR 382 + + S KE+ +++ S S++ +D R ++ + + N + + Sbjct: 445 RDGKEKLEKNSTSLKEKEHNKEPDS----SVSKEVDDKDAPRTEENKIQHNGNCQLNEEN 500 Query: 383 SSEEREA 389 S + EA Sbjct: 501 LSTKTEA 507 Score = 50.8 bits (120), Expect = 2e-06 Identities = 32/135 (23%), Positives = 54/135 (40%) Query: 257 KLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSH 316 K+ S + P + + M R R+ ++ + + +S RSRSH Sbjct: 136 KINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSH 195 Query: 317 QRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANG 376 RS+ S +S R KR SK R R + + + R +SP + K ++R + Sbjct: 196 TRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRS 255 Query: 377 RSEDRRSSEEREAGE 391 S D+R + E Sbjct: 256 HSRDKRKDTREKIKE 270 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 89.4 bits (220), Expect = 5e-18 Identities = 53/184 (28%), Positives = 92/184 (50%), Gaps = 16/184 (8%) Query: 220 EIREKLEELKRVVAEKQEKRNQERLKRREEREREERE-----KLRRSRSHSKNPKRSRSR 274 EIRE+ E++ K+E R ER K R ERE+ +RE K R + K ++ R Sbjct: 37 EIREREREIETRKEGKKE-RESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95 Query: 275 EHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSR---ERS 331 E ++ R ++E + + + K +EK+ R R+ + R R +R R ++R R ER Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155 Query: 332 KRRSSKERFR-------DQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSS 384 K R KER + +++ +++R R + R+R + K+R + R ++R+ Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215 Query: 385 EERE 388 EER+ Sbjct: 216 EERK 219 Score = 79.3 bits (194), Expect = 5e-15 Identities = 51/206 (24%), Positives = 95/206 (46%), Gaps = 17/206 (8%) Query: 199 LHDNDRRLADHFGGKLHLGFIEIREKLEELKRV-VAEKQEKRNQERLKRREEREREEREK 257 + + +R + GK +E+ E KR EK+ KR + + +++ ER++EERE+ Sbjct: 38 IREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERER 97 Query: 258 LRRSRS-----------HSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSR 306 +R R K K+ R R + + R ERKR R K RE++ R + Sbjct: 98 KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER-KERERKKEEREK 156 Query: 307 SSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDR---- 362 R + +R + ++ R+ +R+ K+R R++ +R+R R ++R Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216 Query: 363 DRKDKKRSYESANGRSEDRRSSEERE 388 +RK +++ N R ++R E +E Sbjct: 217 ERKKERQKDRQTNWREKERGKRERKE 242 Score = 75.5 bits (184), Expect = 8e-14 Identities = 47/174 (27%), Positives = 85/174 (48%), Gaps = 19/174 (10%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRS--RSHSKNPKRSRSREHRRH 279 RE+ ++ K+ +K+E+ ++R + +E +E EE+EK ++ + + K + RE + Sbjct: 79 RERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEE 138 Query: 280 RSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKR-RSSKE 338 R R ERK R R K ++ R R R R + ++ +ER KR R+ KE Sbjct: 139 RKRE---ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195 Query: 339 RFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSS-EEREAGE 391 R + R+R R +K++K+ E R +DR+++ E+E G+ Sbjct: 196 R------------KKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGK 237 Score = 67.8 bits (164), Expect = 2e-11 Identities = 40/151 (26%), Positives = 72/151 (47%), Gaps = 9/151 (5%) Query: 220 EIREKLEELKRVVAEKQEKRNQERLKRR-------EEREREEREKLRRSRSHSKNPKRSR 272 E +++ E + E++EKR ++ K R +ERER+E E+ R R + K R Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE-ERKREERKERERKKEER 154 Query: 273 SREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSK 332 +E R + R++ + +EK + R + + R +R R R+R +ER K Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214 Query: 333 RRS-SKERFRDQDLASCDRDRSSRDRSPRDR 362 + KER +D+ +++R R+R R + Sbjct: 215 KEERKKERQKDRQTNWREKERGKRERKERKK 245 Score = 48.9 bits (115), Expect = 8e-06 Identities = 34/125 (27%), Positives = 53/125 (42%), Gaps = 20/125 (16%) Query: 280 RSRSMSRERKRRTRSKS------------REKRHRHRSRSSSRSRSRSHQRSRHSSRDRS 327 +S RER+ TR + RE+ R R R R R R + + + Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94 Query: 328 RERSKRRSSKERFRDQDLASC----DRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRS 383 RER KRR KE ++ ++R + ++R+RK++++ E R E R Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE----RKERERK 150 Query: 384 SEERE 388 EERE Sbjct: 151 KEERE 155 Score = 48.5 bits (114), Expect = 1e-05 Identities = 42/188 (22%), Positives = 82/188 (43%), Gaps = 11/188 (5%) Query: 105 KKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARA 164 +KR E ++E E K ++ EE + + E+ EG +E +K ++ E+ R Sbjct: 67 EKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRT 126 Query: 165 KKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREK 224 K E +E R ++++ R E + +R G K E+ Sbjct: 127 SK-EGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEK--------EEE 177 Query: 225 LEELKRVVAEKQEKRNQERLKRREERER--EEREKLRRSRSHSKNPKRSRSREHRRHRSR 282 +E +R +K+E+ +ER K RE +ER ++E+ ++ + K ++ + R + Sbjct: 178 RKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGK 237 Query: 283 SMSRERKR 290 +ERK+ Sbjct: 238 RERKERKK 245 Score = 43.9 bits (102), Expect = 3e-04 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 19/116 (16%) Query: 282 RSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFR 341 +S RER+R ++ K+ R R + R +R R ++R RER K+ ER + Sbjct: 35 QSEIREREREIETRKEGKKERESERK--KERREREKRKREREKERKRERGKKEKKGERKK 92 Query: 342 DQDLASCDRDRSSRDRSPRDRDRKDK------KRSYESANGRSEDRRSSEEREAGE 391 ++ R+R R R++++K KR + R + +ERE E Sbjct: 93 EE-----------RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE 137 >gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain containing B [Homo sapiens] Length = 546 Score = 89.4 bits (220), Expect = 5e-18 Identities = 64/165 (38%), Positives = 83/165 (50%), Gaps = 13/165 (7%) Query: 234 EKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRR--HRSRSMSRE--RK 289 +K K E + R ER R RRS S ++P+RSRSR H R H S S RE R+ Sbjct: 241 KKDGKEGAEEIDRHVERRRSRSP--RRSLSPRRSPRRSRSRSHHREGHGSSSFDRELERE 298 Query: 290 RRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCD 349 + + RE + R + R SRS R +R R SR+R R RS+ R K RD+ D Sbjct: 299 KERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDR-----D 353 Query: 350 RDRSSRDRSPRDRDRK-DKKRSYESANGRSEDR-RSSEEREAGEI 392 R+R + R RDR DK+R E R R RS E+R GE+ Sbjct: 354 REREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEV 398 Score = 83.6 bits (205), Expect = 3e-16 Identities = 61/179 (34%), Positives = 97/179 (54%), Gaps = 24/179 (13%) Query: 222 REKLEELKRVVAEKQEKRNQ-ERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHR 280 REK E R +++Q R + E K +E+++ +R K RSRSRE R+HR Sbjct: 378 REKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRE-RKHR 436 Query: 281 SRSMSRERKRRTRSKSREKRHRH----------RSRSSSRSRSRSHQRSRHSSRDRSRER 330 SRS SR +R+RS+S+EK +H RSRS S+ R+ S ++S+ S+E+ Sbjct: 437 SRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEK 496 Query: 331 SKRRS-SKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 S++RS SKER +D S+D+S D+ D++RS +S S++++ + E Sbjct: 497 SRKRSRSKERSHKRD------HSDSKDQS----DKHDRRRS-QSIEQESQEKQHKNKDE 544 Score = 83.2 bits (204), Expect = 4e-16 Identities = 64/193 (33%), Positives = 87/193 (45%), Gaps = 45/193 (23%) Query: 241 QERLKRREEREREEREK-LRRSRSHSKNPKRSRSREHRRHRSRSMSRERK--RRTRSKSR 297 +E+ ++R ERE +EREK RRSRS + +R RSR RHRSRS SR+RK RR R + R Sbjct: 297 REKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRER 356 Query: 298 EK-------------------RHRHRSRSSSRS---------------------RSRSHQ 317 EK R + R RS RS R R + Sbjct: 357 EKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDK 416 Query: 318 RSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDK--KRSYESAN 375 R + SR RS+ R + R R ++ R RS S + K+K KRS + Sbjct: 417 RDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQ 476 Query: 376 GRSEDRRSSEERE 388 GR++ S++RE Sbjct: 477 GRTDSVEKSKKRE 489 Score = 79.3 bits (194), Expect = 5e-15 Identities = 55/173 (31%), Positives = 86/173 (49%), Gaps = 23/173 (13%) Query: 235 KQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRS 294 + R+++R R +R+RE ++ R R ++ + R E + R RS R +++R+R Sbjct: 337 RSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRG 396 Query: 295 KSREKRH-------RHRS----------RSSSRSRSRSHQRSRHSSRD---RSRERSKRR 334 + EK+H RHR S SRSR R H RSR SR+ RSR RSK + Sbjct: 397 EVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKH-RSRSRSRNAGKRSRSRSKEK 455 Query: 335 SSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEER 387 SSK + ++ ++ S+ R+ D K KKR + + +S R S+ER Sbjct: 456 SSKHKNESKEKSNKRSRSGSQGRT--DSVEKSKKREHSPSKEKSRKRSRSKER 506 Score = 79.3 bits (194), Expect = 5e-15 Identities = 58/179 (32%), Positives = 92/179 (51%), Gaps = 15/179 (8%) Query: 222 REKLEEL-KRVVAEKQEKRNQERLKRRE---EREREEREKLRRSRSHSKNPKRSRSREHR 277 REK E +R + ++R ER K RE ER +E+ RSR + K ++ R Sbjct: 356 REKENERGRRRDRDYDKERGNEREKERERSRERSKEQ-----RSRGEVEEKKHKEDKDDR 410 Query: 278 RHR-SRSMSRERKRRTRSKSREKRHRHRSRS---SSRSRSRSHQR-SRHSSRDRSRERSK 332 RHR + S++ K+ +RS+SRE++HR RSRS RSRSRS ++ S+H + + + + Sbjct: 411 RHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKR 470 Query: 333 RRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGE 391 RS + D S R+ S R R R K+RS++ + S+D+ +R + Sbjct: 471 SRSGSQGRTDSVEKSKKREHSPSKEKSRKRSR-SKERSHKRDHSDSKDQSDKHDRRRSQ 528 Score = 78.6 bits (192), Expect = 9e-15 Identities = 65/192 (33%), Positives = 96/192 (50%), Gaps = 33/192 (17%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREERERE-EREKLRRSRSHSKNPKRSRSREHRRHR 280 RE+ +E +R ++ + +R +ERER ER K +RSR + K ++ RRHR Sbjct: 354 REREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHR 413 Query: 281 ------------SRSMSRERKRRTRSKSREKRHRHRSRSSSR-------SRSRSHQRSRH 321 SRS SRERK R+RS+SR R RSRS + S+ +S++RSR Sbjct: 414 DDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRS 473 Query: 322 SSRDR--SRERSKRRS---SKERFRDQDLASCDRDRSSRDRSPRDR-DRKDKKRSYESAN 375 S+ R S E+SK+R SKE+ R R RS RD D KD+ ++ Sbjct: 474 GSQGRTDSVEKSKKREHSPSKEKSR-------KRSRSKERSHKRDHSDSKDQSDKHDRRR 526 Query: 376 GRSEDRRSSEER 387 +S ++ S E++ Sbjct: 527 SQSIEQESQEKQ 538 Score = 74.3 bits (181), Expect = 2e-13 Identities = 57/196 (29%), Positives = 92/196 (46%), Gaps = 27/196 (13%) Query: 219 IEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREK-LRRSRSHSKNPKRSRSREHR 277 +E R + + + +R++ R RE ++ L R + + + ++ RE Sbjct: 255 VERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKE 314 Query: 278 RHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRS-------------------RSRSHQR 318 R RSRS+ R +RR RS+SRE RHR RSRS R R R + + Sbjct: 315 RRRSRSIDRGLERR-RSRSRE-RHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDK 372 Query: 319 SRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRS 378 R + R++ RERS+ RS ++R R ++ DR RD D++D K+ + + RS Sbjct: 373 ERGNEREKERERSRERSKEQRSRG-EVEEKKHKEDKDDRRHRD-DKRDSKKEKKHSRSRS 430 Query: 379 EDRR---SSEEREAGE 391 +R+ S R AG+ Sbjct: 431 RERKHRSRSRSRNAGK 446 Score = 40.4 bits (93), Expect = 0.003 Identities = 45/215 (20%), Positives = 91/215 (42%), Gaps = 23/215 (10%) Query: 96 DCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKV 155 D DR E +R + E + E+ E + E K + + G VEE + Sbjct: 351 DRDREREKENERGRRRDRDYDKERGNEREKERERSRERSK------EQRSRGEVEEKKHK 404 Query: 156 MDEVEKA-RAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKL 214 D+ ++ R KR++++ ++S S ++ + R + + + + H Sbjct: 405 EDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKN--- 461 Query: 215 HLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRS--RSHSKNPKRSR 272 E +EK + R ++ + ++ KR +E+ K RS RSH ++ S+ Sbjct: 462 -----ESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSK 516 Query: 273 SREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRS 307 + + R RS S E+ +S+EK+H+++ + Sbjct: 517 DQSDKHDRRRSQSIEQ------ESQEKQHKNKDET 545 >gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] Length = 202 Score = 86.7 bits (213), Expect = 3e-17 Identities = 53/180 (29%), Positives = 91/180 (50%), Gaps = 10/180 (5%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLR---RSRSHSKNPKRSRSREHRR 278 RE+ + +R ++E R+++R + RE + +REK R + R + +R RE R Sbjct: 19 RERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETER 78 Query: 279 HRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSS------RDRSRERSK 332 R R RERKR+T + + R R R R + R+R R+ + R RDR RER + Sbjct: 79 QRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQR 138 Query: 333 RRSSKERFRDQDLASCDRDRSS-RDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGE 391 +R + + + + DR+R +R R ++RK +++ + E RR ++R+ GE Sbjct: 139 QRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198 Score = 78.2 bits (191), Expect = 1e-14 Identities = 44/158 (27%), Positives = 78/158 (49%), Gaps = 5/158 (3%) Query: 234 EKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTR 293 E+Q +R +E + +E +R++ R +++ +N R R R R R +ER+R+ Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61 Query: 294 SKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSK---ERFRDQDLASCDR 350 + +R R R + R R R QR R DR R++ + R K +R R+++ R Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG-GR 120 Query: 351 DRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 +R + RDR+R +++R E R +R+ +RE Sbjct: 121 ERDKQTERERDRER-ERQRQRERERQRQRERKRETDRE 157 Score = 76.3 bits (186), Expect = 5e-14 Identities = 45/150 (30%), Positives = 75/150 (50%), Gaps = 6/150 (4%) Query: 244 LKRREERERE-EREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHR 302 ++R+ ER+RE +R K + + +++ RHR R RER R+T + +R + Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60 Query: 303 HRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQD---LASCDRDRSSRDRSP 359 R R R R + R R R RER KR++ +ER +D+D DR+R + Sbjct: 61 ERDRQRQRERETERETERQRERQRQRER-KRQTDRERDKDRDRERKRETDRNRERNRKGG 119 Query: 360 RDRDRK-DKKRSYESANGRSEDRRSSEERE 388 R+RD++ +++R E R +R +RE Sbjct: 120 RERDKQTERERDRERERQRQRERERQRQRE 149 Score = 31.6 bits (70), Expect = 1.3 Identities = 39/202 (19%), Positives = 79/202 (39%), Gaps = 24/202 (11%) Query: 96 DCDRRTEVAKKRLAETQEEISAEVAAKA-ERVHELNEEIGKLLAKVEQLGAEGNVEESQK 154 D + TE + R E + + E + +R E + + + + Q + + ++ Sbjct: 12 DRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERE 71 Query: 155 VMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDR-RLADHFGGK 213 E E+ R ++R+ E + + ++ + + DR R + GG+ Sbjct: 72 TERETERQRERQRQRERKRQTDRERDKDRDRERK-----------RETDRNRERNRKGGR 120 Query: 214 LHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREERERE----------EREKLRRSRS 263 E RE+ E +R ++E++ Q KR +RER+ ER+K R+ Sbjct: 121 ERDKQTE-RERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179 Query: 264 HSKNPKRSRSREHRRHRSRSMS 285 K + R + +R +S Sbjct: 180 KEKKKEEKRREDKKRKWGEGIS 201 >gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] Length = 494 Score = 85.1 bits (209), Expect = 1e-16 Identities = 60/186 (32%), Positives = 85/186 (45%), Gaps = 32/186 (17%) Query: 235 KQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHR----------------- 277 K R+Q R + ++E+ R ++ RSRSHS RS+S++ Sbjct: 231 KSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRS 290 Query: 278 --RHRSRSMSRER--KRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSK- 332 RH+S+S SR R +RR + R R RS+ S +SRS RS+ SR RSR RSK Sbjct: 291 PSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKS 350 Query: 333 ----------RRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRR 382 R S+ R R + + R R S+ S +K KK + + RS R Sbjct: 351 KDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRS 410 Query: 383 SSEERE 388 S+ERE Sbjct: 411 VSKERE 416 Score = 83.6 bits (205), Expect = 3e-16 Identities = 69/191 (36%), Positives = 95/191 (49%), Gaps = 18/191 (9%) Query: 207 ADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSK 266 AD G+ + G IE ++KR + EK + + R+ R E++ RR RS+S Sbjct: 133 ADAHKGRKNEGVIEF-VSYSDMKRAL----EKLDGTEVNGRKIRLVEDKPGSRRRRSYS- 186 Query: 267 NPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRH-RHRSRSSSRSRSRSHQRSRHSSRD 325 RSR H R RSRS RK R+RS S + H + RSRS S SRSRS RSR SR Sbjct: 187 -----RSRSHSRSRSRS-RHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS 240 Query: 326 RSRERSKRRSSKERFRDQDLASCDRDRSSRDRSP-----RDRDRKDKKRSYESANGRSED 380 RS++ R SKE+ R + ++ S+D++ D K K RS +S+ Sbjct: 241 RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS 300 Query: 381 RRSSEEREAGE 391 R S+ER E Sbjct: 301 RSRSQERRVEE 311 Score = 80.1 bits (196), Expect = 3e-15 Identities = 63/188 (33%), Positives = 87/188 (46%), Gaps = 42/188 (22%) Query: 239 RNQERLKRREEREREEREKLRRSRS-HSKNPKR----SRSREHRRHRSRSMSRERKRRTR 293 R+ R + R R+ R + S+S HSK+ R SRSR R RS+S SR +K ++R Sbjct: 189 RSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSR 248 Query: 294 SKSREKRHRHRSRSSSRSRSRSHQ---------------RSRHSSRDRSRERSKRRSSKE 338 S S+EK R RS S+ +SRS+S +SR SR +S+ +S+ RS + Sbjct: 249 SPSKEK-SRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQER 307 Query: 339 RFRDQDLASCDRDRS---------------------SRDRSPRDRDRKDKKRSYESANGR 377 R ++ S R RS SR RS RK +KRS E + R Sbjct: 308 RVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSR 367 Query: 378 SEDRRSSE 385 S R SE Sbjct: 368 SRSRSKSE 375 Score = 75.1 bits (183), Expect = 1e-13 Identities = 47/152 (30%), Positives = 77/152 (50%), Gaps = 2/152 (1%) Query: 235 KQEKRNQERLKRREER-EREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTR 293 + + +++ R + +E R E E+R + R RS K+ ++SRSR + SRS SR R + Sbjct: 293 RHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD 352 Query: 294 SKSREKRHRHRSRSSSRSRSRSHQ-RSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDR 352 + KR R SRS SRSRS+S + R R S RD SK++ ++ R Q + Sbjct: 353 KRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVS 412 Query: 353 SSRDRSPRDRDRKDKKRSYESANGRSEDRRSS 384 R+ + + +++ + E+A E R S Sbjct: 413 KEREHAKSESSQREGRGESENAGTNQETRSRS 444 Score = 68.9 bits (167), Expect = 7e-12 Identities = 67/266 (25%), Positives = 111/266 (41%), Gaps = 20/266 (7%) Query: 138 AKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYL 197 +K G+ S+ ++R+KK ++ + + S K R A Sbjct: 216 SKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEE 275 Query: 198 GLHDNDR-RLADHFGGKLHLGFIEIREKLEELKRVVAEKQEK----RNQER-LKRREERE 251 + +ND H + R + +E +RV EK+ R+QE+ L++ R Sbjct: 276 KIQNNDNVGKPKSRSPSRHKSKSKSRSRSQE-RRVEEEKRGSVSRGRSQEKSLRQSRSRS 334 Query: 252 REEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSK------------SREK 299 R + RSRS SK+ + + R+ R SRS SR R + RS+ S++K Sbjct: 335 RSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKK 394 Query: 300 RHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRS-SRDRS 358 + RS SRS SRS + R ++ S +R R S+ +Q+ S R S S+ Sbjct: 395 KKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNL 454 Query: 359 PRDRDRKDKKRSYESANGRSEDRRSS 384 P + + K S + +S R +S Sbjct: 455 PSESRSRSKSASKTRSRSKSRSRSAS 480 Score = 65.9 bits (159), Expect = 6e-11 Identities = 67/258 (25%), Positives = 112/258 (43%), Gaps = 26/258 (10%) Query: 100 RTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEV 159 R++ K R ++ S +A R + ++ + + + +G + S+ Sbjct: 241 RSKKEKSRSPSKEKSRSRSHSAGKSR-SKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSK 299 Query: 160 EKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI 219 ++R+++R EE R S+ Q++ LR S G + R K G Sbjct: 300 SRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK-RKGRK 358 Query: 220 EIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRS--RSHSKNPKRSRSREHR 277 RE E R + + +R+++R +R+ + ++K + RS S++P RS S+E Sbjct: 359 RSRE--ESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKERE 416 Query: 278 RHRSRSMSRERK---------RRTRSKSR-----------EKRHRHRSRSSSRSRSRSHQ 317 +S S RE + + TRS+SR E R R +S S +RSRS+S Sbjct: 417 HAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRS 476 Query: 318 RSRHSSRDRSRERSKRRS 335 RS S RSR RS RS Sbjct: 477 RSASRSPSRSRSRSHSRS 494 Score = 63.5 bits (153), Expect = 3e-10 Identities = 59/255 (23%), Positives = 106/255 (41%), Gaps = 31/255 (12%) Query: 150 EESQKVMDEVEKARAK-KREAEEVYRNS---------MPASSFQQQKLRVCEVCSAYLGL 199 E+S+ K+R+K K +AEE +N+ P+ + K R Sbjct: 253 EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRS---------- 302 Query: 200 HDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLR 259 +RR+ + G + G R + + L++ + + K R + +++R+ + Sbjct: 303 RSQERRVEEEKRGSVSRG----RSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK 358 Query: 260 RSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSR--SRSRSHQ 317 RSR S++ RSRS+ R + S + ++ K +E R +SRS SR S+ R H Sbjct: 359 RSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHA 418 Query: 318 RSRHSSRDRSRE-----RSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYE 372 +S S R+ E ++ S+ R + + + SR +S + K RS Sbjct: 419 KSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRS 478 Query: 373 SANGRSEDRRSSEER 387 ++ S R S R Sbjct: 479 ASRSPSRSRSRSHSR 493 >gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] Length = 290 Score = 85.1 bits (209), Expect = 1e-16 Identities = 51/177 (28%), Positives = 87/177 (49%), Gaps = 8/177 (4%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRRE---EREREEREKLRRSRSHSKNPKRSRSREHRR 278 R++ + +R EK+ RN++R K+ E +RERE+++ R R + +R R RE R Sbjct: 94 RDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKER 153 Query: 279 HRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSK---RRS 335 R R+ +R T ++ R R + + R R QR R+R +R + R++ Sbjct: 154 ERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKT 213 Query: 336 SKERFRDQDLASCDRDRSSRDRSPRDRDR-KDKKRSYESANGRSEDRRSSEEREAGE 391 ER R+ D +R+ R RDRDR K++ R + R ++R+ ++E E Sbjct: 214 QTERQRETDREG-ERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKE 269 Score = 81.6 bits (200), Expect = 1e-15 Identities = 48/172 (27%), Positives = 82/172 (47%), Gaps = 5/172 (2%) Query: 220 EIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRH 279 EI E K+ E++ R +ER +R +RE+E + + R + + R R+ R Sbjct: 120 EIERDREREKQKGRERERDRGRER-ERDRDREKERERQTEKDRDGQRETETERERDRERE 178 Query: 280 RSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKER 339 + + ER R + + ++R R R R R +R R + R+ RE +RR ER Sbjct: 179 KQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRR---ER 235 Query: 340 FRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGE 391 RD+D +RDR + R ++RK +++ + E RR ++R+ GE Sbjct: 236 QRDRDRGK-ERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286 Score = 75.5 bits (184), Expect = 8e-14 Identities = 50/165 (30%), Positives = 85/165 (51%), Gaps = 12/165 (7%) Query: 234 EKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKR--- 290 ++Q +R++ R K +ER+R+ R++ R R K R+R RE + R RE+++ Sbjct: 76 DRQRERDRVREKTEKERDRD-RKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134 Query: 291 RTRSKSREK---RHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQD-LA 346 R R + RE+ R R + R + R QR + R+R RER K++ +E RD+D Sbjct: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQK-ERETERDRDRQR 193 Query: 347 SCDRDRSSRDRSPRDRDRK---DKKRSYESANGRSEDRRSSEERE 388 +++R + RDR RK +++R + R DRR +R+ Sbjct: 194 DTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRD 238 Score = 69.7 bits (169), Expect = 4e-12 Identities = 37/145 (25%), Positives = 74/145 (51%), Gaps = 5/145 (3%) Query: 248 EEREREEREKLRRSRSHSKNPKRSRSREHRR-HRSRSMSRERKRRTRSKSREKRHRHRSR 306 ++R+RE R+++R ++ R R RE RR + + +R+R+++T + +R + + R Sbjct: 75 DDRQRE-RDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGR 133 Query: 307 SSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRK- 365 R R R +R R ++R R+ K R + + +R++ + RDRDR+ Sbjct: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQR 193 Query: 366 --DKKRSYESANGRSEDRRSSEERE 388 +K+R ++ R R++ ER+ Sbjct: 194 DTEKERERQTDRERDRQRKTQTERQ 218 Score = 60.8 bits (146), Expect = 2e-09 Identities = 42/151 (27%), Positives = 71/151 (47%), Gaps = 13/151 (8%) Query: 250 REREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSS 309 R R ++ RS + K + + +R R R + K R R + R++ R + + ++ Sbjct: 51 RGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETN 110 Query: 310 RSRSRSHQ----RSRHSSRDRSRERSKRRSSKERFRDQD-------LASCDRDRSSRDRS 358 R+R R Q R R + + RER + R +ER RD+D DRD + Sbjct: 111 RNRDREKQTEIERDREREKQKGRERERDR-GRERERDRDREKERERQTEKDRDGQRETET 169 Query: 359 PRDRDR-KDKKRSYESANGRSEDRRSSEERE 388 R+RDR ++K++ E+ R R + +ERE Sbjct: 170 ERERDREREKQKERETERDRDRQRDTEKERE 200 Score = 28.9 bits (63), Expect = 8.4 Identities = 37/190 (19%), Positives = 69/190 (36%), Gaps = 26/190 (13%) Query: 98 DRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMD 157 DR E K R E E E+ E E + + + E + E ++ Sbjct: 124 DREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKER 183 Query: 158 EVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217 E E+ R ++R+ E+ +Q+K + +R D G + Sbjct: 184 ETERDRDRQRDTEKERERQTDRERDRQRKTQT------------ERQRETDREGER---- 227 Query: 218 FIEIREKLEELKRVVAEKQEKRNQERLKRREERE--REEREKLRRSRSHSKNPKRSRSRE 275 E +R ++ R +ER + R+ +E ++ER+K R+ K + R + Sbjct: 228 --------ETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRRED 279 Query: 276 HRRHRSRSMS 285 +R +S Sbjct: 280 KKRKWGEGIS 289 >gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] Length = 285 Score = 85.1 bits (209), Expect = 1e-16 Identities = 53/178 (29%), Positives = 86/178 (48%), Gaps = 20/178 (11%) Query: 231 VVAEKQEKRNQERLKRR-EEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERK 289 ++ E++ +R +ER ++R +ER RE+ ++ + R + R R R R R R +R Sbjct: 56 IIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRD 115 Query: 290 RRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRS------RERSKRRSSKERFRDQ 343 R T ++ +E+R R R R + R R QR +DR R+R + ER+RD+ Sbjct: 116 RETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDR 175 Query: 344 DL-------ASCDRDRS-SRDRSPRDRDR-----KDKKRSYESANGRSEDRRSSEERE 388 + DRDR R++ R+RDR ++K R E GR D+ ER+ Sbjct: 176 ERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQ 233 Score = 77.8 bits (190), Expect = 2e-14 Identities = 49/168 (29%), Positives = 86/168 (51%), Gaps = 13/168 (7%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRRE---------EREREEREKLRRSRSHSKNPKRSR 272 REK E+++ ++Q KR++ER + R+ +R+RE + + R ++ KR + Sbjct: 78 REKDREIEKD-RDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREK 136 Query: 273 SREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSK 332 RE +R R + ++R+ T K R++ R R R Q+ R + RDR RER + Sbjct: 137 DRERQRQREIGIDKDREIETE-KDRDREREMGETERYRDRERERQKQRETRRDRDRERQR 195 Query: 333 RRSSKERFRDQDLASCDRDRSSRDRSPRDRDR-KDKKRSYESANGRSE 379 + +ER RD+ ++DR + RDRD+ +D++R E R + Sbjct: 196 EKEDRERDRDRQ-KEREKDRYRERETGRDRDKERDRERQREKDRDRQK 242 Score = 67.8 bits (164), Expect = 2e-11 Identities = 39/124 (31%), Positives = 66/124 (53%), Gaps = 12/124 (9%) Query: 234 EKQEKRNQERLKRRE-EREREEREKLRRSRSHSKNPKRSRSREHR-----RHRSRSMSRE 287 E+QE+R ++R ++RE +RER+ + ++ + ++ R RE R+R R R+ Sbjct: 121 ERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQ 180 Query: 288 RKRRTR-----SKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRD 342 ++R TR + REK R R R + R + R R + RDR +ER + R +E+ RD Sbjct: 181 KQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRER-QREKDRD 239 Query: 343 QDLA 346 + A Sbjct: 240 RQKA 243 Score = 62.4 bits (150), Expect = 7e-10 Identities = 40/124 (32%), Positives = 65/124 (52%), Gaps = 16/124 (12%) Query: 223 EKLEELKRVVAEKQEKRNQERLKRRE-----------ERERE-EREKLRRSRSHSKNPKR 270 E+ EE +R K+EK ++ER ++RE E++R+ ERE R + +R Sbjct: 121 ERQEERERQRDRKREK-DRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERER 179 Query: 271 SRSREHRRHRSRSMSRERKRRTRSKSREK---RHRHRSRSSSRSRSRSHQRSRHSSRDRS 327 + RE RR R R RE++ R R + R+K + R+R R + R R + R R +DR Sbjct: 180 QKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRD 239 Query: 328 RERS 331 R+++ Sbjct: 240 RQKA 243 Score = 60.5 bits (145), Expect = 3e-09 Identities = 56/175 (32%), Positives = 72/175 (41%), Gaps = 31/175 (17%) Query: 243 RLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSRE---- 298 RL R + E + LR SR P R RE +R R R R K R R K RE Sbjct: 32 RLAMRSQIEDRDVLILRGSRVA---PAIIRERERQRERERQRKR-AKERHREKDREIEKD 87 Query: 299 -KRHRHRSRSSSRSRSRSHQRSRHSSRDR--------SRERS---KRRSSKERFRDQDLA 346 R R R R R R R +R R RDR RER KR +ER R +++ Sbjct: 88 RDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREI- 146 Query: 347 SCDRDRSSRDRSPRDRDR----------KDKKRSYESANGRSEDRRSSEEREAGE 391 D+DR RDR+R ++++R + R DR E+E E Sbjct: 147 GIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRE 201 Score = 44.7 bits (104), Expect = 1e-04 Identities = 47/204 (23%), Positives = 84/204 (41%), Gaps = 28/204 (13%) Query: 99 RRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLL---AKVEQLGAEGNVEESQKV 155 R E +KR E E E+ +R + + E + K E+ G E+++ Sbjct: 64 RERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETER- 122 Query: 156 MDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLH 215 +E E+ R +KRE + + + +++ + D DR + Sbjct: 123 QEERERQRDRKREKDRERQRQREIGIDKDREIETEK---------DRDR--------ERE 165 Query: 216 LGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSRE 275 +G E E ++ E + R++ER + +E+RER+ R R + R R RE Sbjct: 166 MGETERYRDRERERQKQRETRRDRDRERQREKEDRERD------RDRQKEREKDRYRERE 219 Query: 276 HRRHRSRSMSRERKRRTRSKSREK 299 R R + RER+R + + R+K Sbjct: 220 TGRDRDKERDRERQRE-KDRDRQK 242 >gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial [Homo sapiens] Length = 213 Score = 85.1 bits (209), Expect = 1e-16 Identities = 50/158 (31%), Positives = 84/158 (53%), Gaps = 13/158 (8%) Query: 242 ERLKRREERERE---EREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRT-----R 293 E + R+ ER RE ER++ + S++ ++ +R R R+ R+R R RER+++T R Sbjct: 15 ETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGER 74 Query: 294 SKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLAS---CDR 350 + RE R R R R + R R + + RH+ DR R++ K R ER RD++ R Sbjct: 75 QRERE-RDRDRQRETERERDKERETDRHTETDRERQKQKEREM-ERVRDREREKQKEMGR 132 Query: 351 DRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 +R + + R+R+R+ ++ ++EDR ERE Sbjct: 133 ERQTDRETDRERERQAERERETGRERKTEDRHRERERE 170 Score = 75.5 bits (184), Expect = 8e-14 Identities = 51/154 (33%), Positives = 81/154 (52%), Gaps = 12/154 (7%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRRE-ERERE-EREKLR-----RSRSHSKNPKRSRSR 274 RE+ ++ R E+Q +R ++R ++RE ERER+ ERE R R R K + R R Sbjct: 62 REREKQTDRE-GERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVR 120 Query: 275 EHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRR 334 + R + + M RER+ + +R R R + R R ++ R R R+R RER ++R Sbjct: 121 DREREKQKEMGRERQTDRETDRERERQAERERETGRER-KTEDRHRERERERKRERERKR 179 Query: 335 SSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKK 368 +KER R D+ +R+R RDR R+ ++ Sbjct: 180 ETKERERHTDM---ERERQRETDRKRDRQRESER 210 Score = 75.1 bits (183), Expect = 1e-13 Identities = 49/170 (28%), Positives = 77/170 (45%), Gaps = 4/170 (2%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLR-RSRSHSKNPKRSRSREHRRHR 280 RE E R K E R+ ER ++R+ ER++ R R + + +R R RE R R Sbjct: 25 RETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDR 84 Query: 281 SRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRER-SKRRSSKER 339 R RER + + + R R + R R R R ++ RER + R + +ER Sbjct: 85 QRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRER 144 Query: 340 FRDQDL-ASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 R + R+R + DR R+R+R+ K+ + +R + ERE Sbjct: 145 ERQAERERETGRERKTEDRH-RERERERKRERERKRETKERERHTDMERE 193 Score = 73.2 bits (178), Expect = 4e-13 Identities = 47/158 (29%), Positives = 71/158 (44%), Gaps = 14/158 (8%) Query: 234 EKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKR--SRSREHRRHRSRSMSRERKRR 291 EKQ R ER +R ER+R+ + + R R + R RE ++ + R M R R R Sbjct: 65 EKQTDREGER-QRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE 123 Query: 292 TRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRD 351 + R R R + R R R +R R + R+R E R +ER R+++ Sbjct: 124 REKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERE------- 176 Query: 352 RSSRDRSPRDRDR-KDKKRSYESANGRSEDRRSSEERE 388 R R ++R+R D +R + R DR+ ERE Sbjct: 177 ---RKRETKERERHTDMERERQRETDRKRDRQRESERE 211 Score = 62.8 bits (151), Expect = 5e-10 Identities = 39/130 (30%), Positives = 62/130 (47%), Gaps = 7/130 (5%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRS 281 R++ E +R + ++ + +R++++ERE R R K R R + R Sbjct: 84 RQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRE 143 Query: 282 RSMSRERKRRT-RSKSREKRHRHRSRSSSRSRSR---SHQRSRHSSRDRSRERS---KRR 334 R ER+R T R + E RHR R R R R R + +R RH+ +R R+R KR Sbjct: 144 RERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRD 203 Query: 335 SSKERFRDQD 344 +E R++D Sbjct: 204 RQRESERERD 213 Score = 57.0 bits (136), Expect = 3e-08 Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 10/124 (8%) Query: 276 HRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRS 335 H + +M R+R+RR R RE+ S++ R R QR R +R+R R+R + + Sbjct: 9 HTHTETETMDRQRERR-RETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQ 67 Query: 336 SKERFRDQDLASCDRDRSSRDRSPRDRDR---------KDKKRSYESANGRSEDRRSSEE 386 + Q DRDR RD++R +++++ E R DR ++ Sbjct: 68 TDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQ 127 Query: 387 REAG 390 +E G Sbjct: 128 KEMG 131 Score = 56.2 bits (134), Expect = 5e-08 Identities = 38/132 (28%), Positives = 58/132 (43%), Gaps = 15/132 (11%) Query: 234 EKQEKRNQERLKRREEREREEREKLR-RSRSHSKNPKRSRSREHRRHRSRSMSRERKRRT 292 E++ R+ E + R++++ E E++R R R K R R + R R ER+R T Sbjct: 95 ERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERET 154 Query: 293 -RSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRD 351 R + E RHR R R R R R + R+R + + R + DR Sbjct: 155 GRERKTEDRHRERERERKRERERKRETKE---RERHTDMERERQRE----------TDRK 201 Query: 352 RSSRDRSPRDRD 363 R + S R+RD Sbjct: 202 RDRQRESERERD 213 Score = 54.3 bits (129), Expect = 2e-07 Identities = 50/212 (23%), Positives = 89/212 (41%), Gaps = 18/212 (8%) Query: 83 ELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQ 142 E + MD + + DR + AK+ E + +R E N E + + +Q Sbjct: 13 ETETMDRQRERRRETDRERDRAKESKTEDRHS-----ERDRQRDRERNRERDRDREREKQ 67 Query: 143 LGAEGNVE-ESQKVMD---EVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLG 198 EG + E ++ D E E+ R K+RE + R++ Q+QK R E Sbjct: 68 TDREGERQRERERDRDRQRETERERDKERETD---RHTETDRERQKQKEREME------R 118 Query: 199 LHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKL 258 + D +R G + RE+ + +R +E++ ++R + RE + ERE+ Sbjct: 119 VRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERK 178 Query: 259 RRSRSHSKNPKRSRSREHRRHRSRSMSRERKR 290 R ++ ++ R R+ R R RE +R Sbjct: 179 RETKERERHTDMERERQRETDRKRDRQRESER 210 Score = 51.2 bits (121), Expect = 2e-06 Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 15/116 (12%) Query: 285 SRERKRRTRSKSREK-RHRHRSRSSSRSRSRSHQ---RSRHSSRDRSRERSKRRSSKERF 340 S+ R T +++ R R R R + R R R+ + RHS RDR R+R + R ER Sbjct: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNR---ERD 59 Query: 341 RDQDL-ASCDRDRSSRDRSPRDRDR-------KDKKRSYESANGRSEDRRSSEERE 388 RD++ DR+ + RDRDR +DK+R + +R+ +ERE Sbjct: 60 RDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKERE 115 >gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] Length = 484 Score = 84.7 bits (208), Expect = 1e-16 Identities = 59/162 (36%), Positives = 89/162 (54%), Gaps = 10/162 (6%) Query: 234 EKQEKRNQERLKRREERERE-EREKLRRSRSHSKNPKRSRSREHRRHRS----RSMSRER 288 +K+EKR R + R R R + RRSRS S+ S+SR RR +S RS SRER Sbjct: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300 Query: 289 KRRTR--SKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLA 346 RR+R SK+R+K+ + + S++ +S+ +R SR SRER +RR S+ R Sbjct: 301 GRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARR-SRSASRER-RRRRSRSGTRSPKKP 358 Query: 347 SCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 + + SR SPR R +K+KK+ + R E RS+ +++ Sbjct: 359 RSPKRKLSRSPSPR-RHKKEKKKDKDKERSRDERERSTSKKK 399 Score = 78.2 bits (191), Expect = 1e-14 Identities = 63/195 (32%), Positives = 89/195 (45%), Gaps = 30/195 (15%) Query: 223 EKLEELKRVVAEKQEKRNQE-----RLKRREEREREEREKLRRSRSHSKNPKRSRS--RE 275 +K EE +R + R + R +R R R RSR SK+P+R RS RE Sbjct: 240 DKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRE 299 Query: 276 H-RRHRSRSMSRERKRRTRSKSREK--------------RHRHRSRSSSRSRSRSHQRSR 320 RR RS S +R++K+ + K R K R R R SRS +RS ++ R Sbjct: 300 RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPR 359 Query: 321 HSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDR-----KDKKRSYESAN 375 R SR S RR KE+ +D+D +R R R+RS + + KD++R ES Sbjct: 360 SPKRKLSRSPSPRRHKKEKKKDKDK---ERSRDERERSTSKKKKSKDKEKDRERKSESDK 416 Query: 376 GRSEDRRSSEEREAG 390 + R +E E G Sbjct: 417 DVKQVTRDYDEEEQG 431 Score = 72.8 bits (177), Expect = 5e-13 Identities = 47/137 (34%), Positives = 68/137 (49%), Gaps = 2/137 (1%) Query: 253 EEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSR 312 E +++R ++S +E +R SRS SR R+RRT S SR +R R RSR S S+ Sbjct: 221 EAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSK 280 Query: 313 SRSHQRSRHSSRDR--SRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRS 370 SRS +RS+ R R SRER +R S + RD+ ++ RS R+ + S Sbjct: 281 SRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSAS 340 Query: 371 YESANGRSEDRRSSEER 387 E RS S ++ Sbjct: 341 RERRRRRSRSGTRSPKK 357 Score = 72.4 bits (176), Expect = 7e-13 Identities = 52/169 (30%), Positives = 80/169 (47%), Gaps = 22/169 (13%) Query: 237 EKRNQERLKRREEREREEREKLRRSRSHSKN-PKRSRSREHRRHRSRSMSRERKRRTRSK 295 + R++ R K R RE+ RRSRS SK K+ +E +R ++ S RR+RS Sbjct: 280 KSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSA 339 Query: 296 SREKRHRHRSRSSSRSRS---------------RSHQRSRHSSRDRSRERSKRRSSKERF 340 SRE+R R RSRS +RS R H++ + +D+ R R +R ER Sbjct: 340 SRERRRR-RSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDER----ERS 394 Query: 341 RDQDLASCDRDRSSRDRSPRDRDRKDKKRSY-ESANGRSEDRRSSEERE 388 + S D+++ +S D+D K R Y E G ++ EE++ Sbjct: 395 TSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKK 443 Score = 64.7 bits (156), Expect = 1e-10 Identities = 40/163 (24%), Positives = 83/163 (50%), Gaps = 5/163 (3%) Query: 230 RVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERK 289 R ++ ++K+ +++ K+R + + RRSRS S+ +R RSR R + S +RK Sbjct: 305 RSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRK 364 Query: 290 RRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCD 349 +RS S + + + + + RSR + S + +S+++ K R K D+D+ Sbjct: 365 -LSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSE-SDKDVKQVT 422 Query: 350 RDRSSRDRS-PRDRDRKDKKRSYESANGRSEDRRSSEEREAGE 391 RD ++ ++++K++K+ E+ G + + S E+ G+ Sbjct: 423 RDYDEEEQGYDSEKEKKEEKKPIET--GSPKTKECSVEKGTGD 463 Score = 52.4 bits (124), Expect = 7e-07 Identities = 51/202 (25%), Positives = 84/202 (41%), Gaps = 22/202 (10%) Query: 157 DEVEKARAKKREAEEVYRNSMPASS----FQQQKLRVCEVCSAYLGLHDNDRRLADHFG- 211 D+ E+ R R R P+SS + + R S + RR H Sbjct: 240 DKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRE 299 Query: 212 -GKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKR 270 G+ + R+K +E K K ++ +R RE R RRSRS +++PK+ Sbjct: 300 RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRR--RRSRSGTRSPKK 357 Query: 271 SRS-----------REHRRHRSRSMSRERKR--RTRSKSREKRHRHRSRSSSRSRSRSHQ 317 RS R H++ + + +ER R R RS S++K+ + + + R +S S + Sbjct: 358 PRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRER-KSESDK 416 Query: 318 RSRHSSRDRSRERSKRRSSKER 339 + +RD E S KE+ Sbjct: 417 DVKQVTRDYDEEEQGYDSEKEK 438 Score = 36.6 bits (83), Expect = 0.040 Identities = 24/125 (19%), Positives = 55/125 (44%), Gaps = 16/125 (12%) Query: 234 EKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTR 293 +K++K+++++ + R+ERER +K K+S+ +E R R ++ K+ TR Sbjct: 375 KKEKKKDKDKERSRDERERSTSKK-----------KKSKDKEKDRERKSESDKDVKQVTR 423 Query: 294 SKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRS 353 E++ S + ++ + +++E S + + + R+ + D Sbjct: 424 DYDEEEQ-----GYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEE 478 Query: 354 SRDRS 358 D S Sbjct: 479 DMDMS 483 >gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens] Length = 1031 Score = 84.0 bits (206), Expect = 2e-16 Identities = 59/164 (35%), Positives = 91/164 (55%), Gaps = 15/164 (9%) Query: 230 RVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRR-HRSRSMSRER 288 R ++K+ KR +R R +R+R RR RS S++ +RSRSR+ +R RSRS R+R Sbjct: 25 RSPSDKRSKRGDDRRSRSRDRDR------RRERSRSRDKRRSRSRDRKRLRRSRSRERDR 78 Query: 289 KR-RTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRR-----SSKERFRD 342 R R RS+SR++R R RSRS R RSRS S + +R RSK + SSKE+ +D Sbjct: 79 SRERRRSRSRDRR-RSRSRSRGR-RSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKD 136 Query: 343 QDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEE 386 +D ++++ + + + + +KR R E R+ + E Sbjct: 137 KDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAME 180 Score = 81.3 bits (199), Expect = 1e-15 Identities = 49/143 (34%), Positives = 74/143 (51%), Gaps = 2/143 (1%) Query: 246 RREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREK-RHRHR 304 R +R +R RRSRS ++ +R RSR + RSRS R+R RR+RS+ R++ R R R Sbjct: 25 RSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRR 84 Query: 305 SRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDR 364 SRS R RSRS R R S +SK+ ++ R +++ +D+ ++ D Sbjct: 85 SRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKE-DE 143 Query: 365 KDKKRSYESANGRSEDRRSSEER 387 K+K N E+ R +ER Sbjct: 144 KEKDAGNFDQNKLEEEMRKRKER 166 Score = 79.7 bits (195), Expect = 4e-15 Identities = 54/154 (35%), Positives = 77/154 (50%), Gaps = 17/154 (11%) Query: 247 REEREREEREKLR-----RSRSHSKNPKRSRSREHRRHRSRSMSRERKR-----RTRSKS 296 RE R +R R RSRS S + KRS+ + RR RSR R R+R + RS+S Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62 Query: 297 REKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRD 356 R+++ RSRS R RSR +RSR SRDR R RS+ R + R S + SR Sbjct: 63 RDRKRLRRSRSRERDRSRERRRSR--SRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRS 120 Query: 357 RSPRDRDRKDKKRSYESANGRSEDRRSSEEREAG 390 + D K++ + +D+ +E++AG Sbjct: 121 KEKTDGGESSKEKKKD-----KDDKEDEKEKDAG 149 Score = 75.9 bits (185), Expect = 6e-14 Identities = 54/157 (34%), Positives = 73/157 (46%), Gaps = 15/157 (9%) Query: 238 KRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSR 297 KR+ R R R R +RS+ RSR R+ RR RSRS KRR+RS+ R Sbjct: 10 KRSASR-GRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRD---KRRSRSRDR 65 Query: 298 EKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKR--------RSSKERFRDQDLASCD 349 ++ R RSR RSR R RSR R RSR R +R +S K R + D Sbjct: 66 KRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTD 125 Query: 350 RDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEE 386 SS+++ +D+ DK+ E G + + EE Sbjct: 126 GGESSKEKK---KDKDDKEDEKEKDAGNFDQNKLEEE 159 Score = 70.1 bits (170), Expect = 3e-12 Identities = 49/124 (39%), Positives = 64/124 (51%), Gaps = 6/124 (4%) Query: 269 KRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSR 328 KRS SR RSRS S KR R R R R R R RSRSR +RSR SRDR R Sbjct: 10 KRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR--SRDRKR 67 Query: 329 ERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDR-RSSEER 387 R R ++R R++ + R R R R R R+ + S + + ++E+R RS E+ Sbjct: 68 LRRSRSRERDRSRERRRS---RSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKT 124 Query: 388 EAGE 391 + GE Sbjct: 125 DGGE 128 Score = 66.6 bits (161), Expect = 4e-11 Identities = 41/160 (25%), Positives = 78/160 (48%), Gaps = 9/160 (5%) Query: 235 KQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRS 294 + R +ER + R++R R++ R RS S+ RSR R R R R R+ R+RS Sbjct: 43 RDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDR-----RRSRSRS 97 Query: 295 KSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSS 354 + R R S ++ +RS + + + S+E+ K + KE +++D + D+++ Sbjct: 98 RGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLE 157 Query: 355 RDRSPRDRDRKDKKRSYE---SANGRSEDRRSSEEREAGE 391 + R ++R +K R + + E ++ EE + G+ Sbjct: 158 EEMRKR-KERVEKWREEQRKKAMENIGELKKEIEEMKQGK 196 >gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] Length = 2426 Score = 82.4 bits (202), Expect = 6e-16 Identities = 62/158 (39%), Positives = 86/158 (54%), Gaps = 14/158 (8%) Query: 238 KRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREH--RRHRSRSMSRERKRRTRSK 295 K E+ K+ + R++ E+EK R S S++ KRS+S EH R+ S S SR RKR ++SK Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRS-KRSKSSEHKSRKRTSESRSRARKRSSKSK 1855 Query: 296 SREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKE-RFRDQDLASCDRDRSS 354 S HRS++ SRSRSR R R SSR RS+ R +R SKE R R S R+R Sbjct: 1856 S------HRSQTRSRSRSR---RRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKR 1906 Query: 355 RDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI 392 + S RD +RK + + + RS S R + + Sbjct: 1907 KRSSSRD-NRKTVRARSRTPSRRSRSHTPSRRRRSRSV 1943 Score = 81.3 bits (199), Expect = 1e-15 Identities = 54/173 (31%), Positives = 86/173 (49%), Gaps = 8/173 (4%) Query: 218 FIEIREKLEELK----RVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRS 273 F+++++ E+ K R EK++KR+ L+ R +R + K R+ S S++ R RS Sbjct: 1793 FVKVKDTHEKSKKNKNRDKGEKEKKRDSS-LRSRSKRSKSSEHKSRKRTSESRSRARKRS 1851 Query: 274 REHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKR 333 + + HRS++ SR R RR R SR + RS S+ + + + R SR+R R+RS Sbjct: 1852 SKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSS 1911 Query: 334 RSSKERFRDQDLASCDRDRS---SRDRSPRDRDRKDKKRSYESANGRSEDRRS 383 R +++ R + R RS SR R R R+ S R+ RRS Sbjct: 1912 RDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRS 1964 Score = 70.5 bits (171), Expect = 3e-12 Identities = 65/169 (38%), Positives = 86/169 (50%), Gaps = 15/169 (8%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRH-- 279 R++ E + ++ K R + R R + RSRS S+ +RS S+E R+ Sbjct: 1837 RKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRG-RRSVSKEKRKRSP 1895 Query: 280 RSRSMSRERKRRTRSKSREKRH--RHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRS-- 335 + RS SRERKR+ RS SR+ R R RSR+ SR RSRSH SR R RSR +RRS Sbjct: 1896 KHRSKSRERKRK-RSSSRDNRKTVRARSRTPSR-RSRSHTPSR---RRRSRSVGRRRSFS 1950 Query: 336 -SKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRS-YESANGRSEDRR 382 S R R + + R S R R+P R R +RS S R+ RR Sbjct: 1951 ISPSR-RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR 1998 Score = 70.1 bits (170), Expect = 3e-12 Identities = 58/171 (33%), Positives = 89/171 (52%), Gaps = 12/171 (7%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRS-RSREHRRHR 280 R K + + K+ ++ R ++R + + R + R SRS S+ +RS RSR R R Sbjct: 1825 RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTR-SRSRSRRRRRSSRSRSKSRGR 1883 Query: 281 SRSMSRERKRRT---RSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSK 337 RS+S+E+++R+ RSKSRE++ + S +R R+ R+ S R RS S+RR S+ Sbjct: 1884 -RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRT-PSRRSRSHTPSRRRRSR 1941 Query: 338 E--RFRDQDLASCDRDR--SSRDRSPRDRDRKDKKRS-YESANGRSEDRRS 383 R R ++ R R S R R+P R R +RS S R+ RRS Sbjct: 1942 SVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRS 1992 Score = 66.6 bits (161), Expect = 4e-11 Identities = 61/170 (35%), Positives = 85/170 (50%), Gaps = 20/170 (11%) Query: 229 KRVVAEKQEKRNQERLKRREEREREE---REKLRRSRSHSKNPKRSRSREHR---RHRSR 282 +R V++++ KR+ + + ER+R+ R+ + R+ S+ P R RSR H R RSR Sbjct: 1883 RRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSR-RSRSHTPSRRRRSR 1941 Query: 283 SMSRER------KRRTRSKSREKR-HRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRS 335 S+ R R RR+R+ SR R RSR+ SR +RSR SR RSR S+RR Sbjct: 1942 SVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR-RSRTPSRRRR 2000 Query: 336 SKERFRDQDLASCDRDRSSRDRSPR----DRDRKDKKRSYESANGRSEDR 381 S+ R + S R R R+P R +KRS S GRS R Sbjct: 2001 SRSVVRRRSF-SISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049 Score = 65.5 bits (158), Expect = 8e-11 Identities = 56/160 (35%), Positives = 74/160 (46%), Gaps = 14/160 (8%) Query: 233 AEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHR-----RHRSRSMSRE 287 + + + R++ R +RR R R K R RS SK KR RS +HR R R RS SR+ Sbjct: 1856 SHRSQTRSRSRSRRRRRSSRS-RSKSRGRRSVSKE-KRKRSPKHRSKSRERKRKRSSSRD 1913 Query: 288 RKRRTRSKSREKRHRHRSRSSS---RSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQD 344 ++ R++SR R RS + S RSRS +RS S R RRS R + Sbjct: 1914 NRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRT 1973 Query: 345 LASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSS 384 + R S R R+P R R +R RS RR S Sbjct: 1974 PSRRSRTPSRRSRTPSRRSRTPSRR----RRSRSVVRRRS 2009 Score = 32.3 bits (72), Expect = 0.76 Identities = 32/110 (29%), Positives = 47/110 (42%), Gaps = 28/110 (25%) Query: 302 RHRSRSSSRSRSRSHQRSRHSSRDR-----------SRERSKR-----RSSKERFRDQDL 345 R RS +S S + S SS ++ + E+SK+ + KE+ RD L Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822 Query: 346 ASCDRDRSSRDRSPRDRDRK--------DKKRSYESANGRSEDRRSSEER 387 R RS R +S + RK +KRS +S + RS+ R S R Sbjct: 1823 ----RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSR 1868 Score = 30.8 bits (68), Expect = 2.2 Identities = 26/97 (26%), Positives = 53/97 (54%), Gaps = 13/97 (13%) Query: 220 EIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRH 279 EI +K+EE+ V + E R + LK E R+ R ++ + P + +S++H++H Sbjct: 60 EIVQKIEEVLSGVLDT-ELRYKPDLK---EGSRKSRCVSVQTDPTDEIPTK-KSKKHKKH 114 Query: 280 RSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSH 316 ++ K++ + K +EK+++ R S S+++SH Sbjct: 115 KN-------KKKKKKKEKEKKYK-RQPEESESKTKSH 143 >gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] Length = 2303 Score = 82.4 bits (202), Expect = 6e-16 Identities = 62/158 (39%), Positives = 86/158 (54%), Gaps = 14/158 (8%) Query: 238 KRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREH--RRHRSRSMSRERKRRTRSK 295 K E+ K+ + R++ E+EK R S S++ KRS+S EH R+ S S SR RKR ++SK Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSLRSRS-KRSKSSEHKSRKRTSESRSRARKRSSKSK 1855 Query: 296 SREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKE-RFRDQDLASCDRDRSS 354 S HRS++ SRSRSR R R SSR RS+ R +R SKE R R S R+R Sbjct: 1856 S------HRSQTRSRSRSR---RRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKR 1906 Query: 355 RDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI 392 + S RD +RK + + + RS S R + + Sbjct: 1907 KRSSSRD-NRKTVRARSRTPSRRSRSHTPSRRRRSRSV 1943 Score = 81.3 bits (199), Expect = 1e-15 Identities = 54/173 (31%), Positives = 86/173 (49%), Gaps = 8/173 (4%) Query: 218 FIEIREKLEELK----RVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRS 273 F+++++ E+ K R EK++KR+ L+ R +R + K R+ S S++ R RS Sbjct: 1793 FVKVKDTHEKSKKNKNRDKGEKEKKRDSS-LRSRSKRSKSSEHKSRKRTSESRSRARKRS 1851 Query: 274 REHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKR 333 + + HRS++ SR R RR R SR + RS S+ + + + R SR+R R+RS Sbjct: 1852 SKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSS 1911 Query: 334 RSSKERFRDQDLASCDRDRS---SRDRSPRDRDRKDKKRSYESANGRSEDRRS 383 R +++ R + R RS SR R R R+ S R+ RRS Sbjct: 1912 RDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRS 1964 Score = 70.5 bits (171), Expect = 3e-12 Identities = 65/169 (38%), Positives = 86/169 (50%), Gaps = 15/169 (8%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRH-- 279 R++ E + ++ K R + R R + RSRS S+ +RS S+E R+ Sbjct: 1837 RKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRG-RRSVSKEKRKRSP 1895 Query: 280 RSRSMSRERKRRTRSKSREKRH--RHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRS-- 335 + RS SRERKR+ RS SR+ R R RSR+ SR RSRSH SR R RSR +RRS Sbjct: 1896 KHRSKSRERKRK-RSSSRDNRKTVRARSRTPSR-RSRSHTPSR---RRRSRSVGRRRSFS 1950 Query: 336 -SKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRS-YESANGRSEDRR 382 S R R + + R S R R+P R R +RS S R+ RR Sbjct: 1951 ISPSR-RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR 1998 Score = 70.1 bits (170), Expect = 3e-12 Identities = 58/171 (33%), Positives = 89/171 (52%), Gaps = 12/171 (7%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRS-RSREHRRHR 280 R K + + K+ ++ R ++R + + R + R SRS S+ +RS RSR R R Sbjct: 1825 RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTR-SRSRSRRRRRSSRSRSKSRGR 1883 Query: 281 SRSMSRERKRRT---RSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSK 337 RS+S+E+++R+ RSKSRE++ + S +R R+ R+ S R RS S+RR S+ Sbjct: 1884 -RSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRT-PSRRSRSHTPSRRRRSR 1941 Query: 338 E--RFRDQDLASCDRDR--SSRDRSPRDRDRKDKKRS-YESANGRSEDRRS 383 R R ++ R R S R R+P R R +RS S R+ RRS Sbjct: 1942 SVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRS 1992 Score = 66.6 bits (161), Expect = 4e-11 Identities = 61/170 (35%), Positives = 85/170 (50%), Gaps = 20/170 (11%) Query: 229 KRVVAEKQEKRNQERLKRREEREREE---REKLRRSRSHSKNPKRSRSREHR---RHRSR 282 +R V++++ KR+ + + ER+R+ R+ + R+ S+ P R RSR H R RSR Sbjct: 1883 RRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSR-RSRSHTPSRRRRSR 1941 Query: 283 SMSRER------KRRTRSKSREKR-HRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRS 335 S+ R R RR+R+ SR R RSR+ SR +RSR SR RSR S+RR Sbjct: 1942 SVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSR-RSRTPSRRRR 2000 Query: 336 SKERFRDQDLASCDRDRSSRDRSPR----DRDRKDKKRSYESANGRSEDR 381 S+ R + S R R R+P R +KRS S GRS R Sbjct: 2001 SRSVVRRRSF-SISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049 Score = 65.5 bits (158), Expect = 8e-11 Identities = 56/160 (35%), Positives = 74/160 (46%), Gaps = 14/160 (8%) Query: 233 AEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHR-----RHRSRSMSRE 287 + + + R++ R +RR R R K R RS SK KR RS +HR R R RS SR+ Sbjct: 1856 SHRSQTRSRSRSRRRRRSSRS-RSKSRGRRSVSKE-KRKRSPKHRSKSRERKRKRSSSRD 1913 Query: 288 RKRRTRSKSREKRHRHRSRSSS---RSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQD 344 ++ R++SR R RS + S RSRS +RS S R RRS R + Sbjct: 1914 NRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRT 1973 Query: 345 LASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSS 384 + R S R R+P R R +R RS RR S Sbjct: 1974 PSRRSRTPSRRSRTPSRRSRTPSRR----RRSRSVVRRRS 2009 Score = 32.3 bits (72), Expect = 0.76 Identities = 32/110 (29%), Positives = 47/110 (42%), Gaps = 28/110 (25%) Query: 302 RHRSRSSSRSRSRSHQRSRHSSRDR-----------SRERSKR-----RSSKERFRDQDL 345 R RS +S S + S SS ++ + E+SK+ + KE+ RD L Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSL 1822 Query: 346 ASCDRDRSSRDRSPRDRDRK--------DKKRSYESANGRSEDRRSSEER 387 R RS R +S + RK +KRS +S + RS+ R S R Sbjct: 1823 ----RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSR 1868 Score = 30.8 bits (68), Expect = 2.2 Identities = 26/97 (26%), Positives = 53/97 (54%), Gaps = 13/97 (13%) Query: 220 EIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRH 279 EI +K+EE+ V + E R + LK E R+ R ++ + P + +S++H++H Sbjct: 60 EIVQKIEEVLSGVLDT-ELRYKPDLK---EGSRKSRCVSVQTDPTDEIPTK-KSKKHKKH 114 Query: 280 RSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSH 316 ++ K++ + K +EK+++ R S S+++SH Sbjct: 115 KN-------KKKKKKKEKEKKYK-RQPEESESKTKSH 143 >gi|42560244 peptidylprolyl isomerase G [Homo sapiens] Length = 754 Score = 82.0 bits (201), Expect = 8e-16 Identities = 61/166 (36%), Positives = 89/166 (53%), Gaps = 22/166 (13%) Query: 236 QEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRH-------RSRSMSRER 288 +EKR + R K R+ +E+EK +S S K+ +RSRS+E + S S+E+ Sbjct: 481 EEKRMRSRSKGRDHENVKEKEK--QSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEK 538 Query: 289 KRRTRSKSRE---KRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSK-ERFRDQD 344 RR +S+SRE + +H S +R RSRS RSR R R+ +R + RS + R+R+Q+ Sbjct: 539 DRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRR-VRSRTHDRDRSRSKEYHRYREQE 597 Query: 345 LASCDRDRSSRDRSPRDRDR-KDKKRSYESANGRSEDRRSSEEREA 389 R RS R+P R R KD++R R D RSSE E+ Sbjct: 598 YRRRGRSRSRERRTPPGRSRSKDRRR-------RRRDSRSSEREES 636 Score = 74.3 bits (181), Expect = 2e-13 Identities = 69/263 (26%), Positives = 122/263 (46%), Gaps = 45/263 (17%) Query: 150 EESQKVMDEVEKARAKKR------EAEEVYRNSMP--ASSFQQQKLRVCEVCSAYLGLHD 201 E+ +KV D K+ +K+R E ++ Y+N + A S + K + H+ Sbjct: 421 EKEKKVKDH--KSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHN 478 Query: 202 N--DRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREE----- 254 ++R+ G+ H ++EK ++ +++ R++E+ K+ E + E Sbjct: 479 RNEEKRMRSRSKGRDHEN---VKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKS 535 Query: 255 REKLRRSRSHSKNPKRSRSRE--HRRHRSRSMSRERKRRTRSKSREKR-------HRHRS 305 +EK RR++S S+ ++ + + R R RS SR+R RR RS++ ++ HR+R Sbjct: 536 KEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYRE 595 Query: 306 RS-SSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDR 364 + R RSRS +R R RS++R +RR RD S +R Sbjct: 596 QEYRRRGRSRSRERRTPPGRSRSKDRRRRR---------------RDSRSSEREESQSRN 640 Query: 365 KDKKRSYESANGRSEDRRSSEER 387 KDK R+ ES + ++ SE+R Sbjct: 641 KDKYRNQESKSSHRKENSESEKR 663 Score = 74.3 bits (181), Expect = 2e-13 Identities = 44/177 (24%), Positives = 86/177 (48%), Gaps = 8/177 (4%) Query: 220 EIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRH 279 E +K+++ K E+ +RN E+ + + + ++ + RS+S K+ + R +H R+ Sbjct: 421 EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN 480 Query: 280 RSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRH-----SSRDRSRERSKRR 334 + M K R +EK + S+ + RSRS ++S+ + D S+ + K R Sbjct: 481 EEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDR 540 Query: 335 SSKERFRDQDLASCDRDRSSRDRS---PRDRDRKDKKRSYESANGRSEDRRSSEERE 388 ++ R R+ D+ +SR R RDR R+ + R+++ RS++ E+E Sbjct: 541 RAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQE 597 Score = 74.3 bits (181), Expect = 2e-13 Identities = 74/308 (24%), Positives = 127/308 (41%), Gaps = 25/308 (8%) Query: 98 DRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMD 157 D+ KKR S E + ER + N K + + NV+E +K D Sbjct: 446 DKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSD 505 Query: 158 ----EVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEV----CSAYLGLHDNDRRLADH 209 + E++R+K++ + +++ S ++K R + C G H + R + Sbjct: 506 SKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRER 565 Query: 210 FGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPK 269 + + R + R E R QE +R R RE R RSRS + + Sbjct: 566 SRSRDRSRRVRSRTHDRDRSRS-KEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRR 624 Query: 270 RSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRS-R 328 R SR R S+S ++++ R SKS ++ S S+SR H S +S ++ R Sbjct: 625 RRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADR 684 Query: 329 ERSKRRSSKERFRDQDLASC-------DRDRSSRDRSPRDR--------DRKDKKRSYES 373 ++S K+ +D +L S ++ RSS ++ + K+KK +ES Sbjct: 685 DQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHES 744 Query: 374 ANGRSEDR 381 + G ED+ Sbjct: 745 SPGTDEDK 752 Score = 72.8 bits (177), Expect = 5e-13 Identities = 69/310 (22%), Positives = 141/310 (45%), Gaps = 41/310 (13%) Query: 107 RLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEK----- 161 R+ E + V+ R +E +++ + ++ N E+ K ++V+K Sbjct: 400 RVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSK 459 Query: 162 ARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEI 221 +R+K +E + + +++++R + + + +++ +D G Sbjct: 460 SRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQ-SDSKGKDQERS--RS 516 Query: 222 REKLEELKRVVAEKQEKRNQERLKRREERERE-------------------EREKLRRSR 262 +EK ++L+ E +++E+ +R + R RE R++ RR R Sbjct: 517 KEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVR 576 Query: 263 SHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHS 322 S + + RSRS+E+ R+R + E +RR RS+SRE+R RS S+ R R + SR S Sbjct: 577 SRTHDRDRSRSKEYHRYREQ----EYRRRGRSRSRERR-TPPGRSRSKDRRRRRRDSRSS 631 Query: 323 SRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRR 382 R+ S+ R +K+++R+Q+ S R ++ S ++ K R + S+N E + Sbjct: 632 EREESQSR-----NKDKYRNQESKSSHR----KENSESEKRMYSKSRDHNSSNNSREKKA 682 Query: 383 SSEEREAGEI 392 ++ +I Sbjct: 683 DRDQSPFSKI 692 Score = 62.0 bits (149), Expect = 9e-10 Identities = 52/190 (27%), Positives = 84/190 (44%), Gaps = 27/190 (14%) Query: 220 EIREKLEELKRVVAEKQEKRNQER-LKRREEREREEREKLRRSRSHSKNPKRSRSREHRR 278 E+ E E + V K+ K R + R+ E+ +K++ +S+SK R+ E Sbjct: 387 ELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDD 446 Query: 279 HRSRSMSRERKRRTRSKSREK----------RHRHRSRSSSRSRSRSHQ----------- 317 + + K ++RSKS+EK R SRS+ R H+ Sbjct: 447 KYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDS 506 Query: 318 RSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGR 377 + + R RS+E+SK+ SK D S ++DR ++ RS R+ D K SY N R Sbjct: 507 KGKDQERSRSKEKSKQLESKSNEHDHS-KSKEKDRRAQSRS-RECDITKGKHSY---NSR 561 Query: 378 SEDRRSSEER 387 + +R S +R Sbjct: 562 TRERSRSRDR 571 Score = 55.1 bits (131), Expect = 1e-07 Identities = 41/191 (21%), Positives = 83/191 (43%), Gaps = 43/191 (22%) Query: 239 RNQERLKR-------REEREREER--------------EKLRRSRSHSKNPKRSRSREHR 277 R+++R +R R+E +R +R +L + + ++P R + R+ Sbjct: 348 RSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKIT 407 Query: 278 RHRSRSMSRERK-------------------RRTRSKSREKRHRHRSRSSSRSRSRSHQR 318 HR+ S S RK RR K + +++ + R+ S+SRS+S ++ Sbjct: 408 DHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEK 467 Query: 319 SRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDR---KDKKRSYESAN 375 S+ RD R++ + + R + +D + D +D++R K+K + ES + Sbjct: 468 SKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKS 527 Query: 376 GRSEDRRSSEE 386 + +S E+ Sbjct: 528 NEHDHSKSKEK 538 Score = 52.4 bits (124), Expect = 7e-07 Identities = 46/182 (25%), Positives = 89/182 (48%), Gaps = 25/182 (13%) Query: 233 AEKQEKRNQERLKRRE-EREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRR 291 A+++E++N+ER + RE + +R +++ ++ + R RR+R+ S SR R R Sbjct: 294 ADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRF 353 Query: 292 TRSKS-----REKRHRHRSRSSSRSR-----------SRSHQRS------RHSSRDRSRE 329 RS++ +E + R R SS R + +QRS R + R+ Sbjct: 354 RRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVS 413 Query: 330 RSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDK--KRSYESANGRSEDRRSSEER 387 S R +++ + +D S ++R R S +D K+K KR+ + +S+++ S+ER Sbjct: 414 ESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKER 473 Query: 388 EA 389 ++ Sbjct: 474 DS 475 Score = 49.7 bits (117), Expect = 5e-06 Identities = 54/238 (22%), Positives = 102/238 (42%), Gaps = 28/238 (11%) Query: 154 KVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213 K ++ K R ++RE E NS PAS Q++L V G R + Sbjct: 293 KADEKERKNRERERERECNPPNSQPAS--YQRRLLVTRSGRKIKGRGPRRYRTPSRSRSR 350 Query: 214 LHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRS 273 R + E ++ ++ + R+ E + ++ +L + + ++P R + Sbjct: 351 -------DRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKE 403 Query: 274 REHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRS-RSRSHQRSRHSSRDRSRERSK 332 R+ HR+ S S RK K ++ H+S S R R S + ++ ++ + R +SK Sbjct: 404 RKITDHRNVSESPNRKNEKEKKVKD----HKSNSKERDIRRNSEKDDKYKNKVKKRAKSK 459 Query: 333 RRS-SKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREA 389 RS SKE+ S ++R S+ +R ++KR + GR + +E+++ Sbjct: 460 SRSKSKEK-------SKSKERDSK------HNRNEEKRMRSRSKGRDHENVKEKEKQS 504 Score = 48.5 bits (114), Expect = 1e-05 Identities = 28/118 (23%), Positives = 55/118 (46%), Gaps = 1/118 (0%) Query: 251 EREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSR 310 ++EE+++ + S S S + S S + S S E +SK R+K+HR SR + Sbjct: 184 KKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKK 243 Query: 311 SRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKK 368 + + ++S+ S+ S + + R +++ +R +SP D K++K Sbjct: 244 EKKK-RKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERK 300 Score = 43.9 bits (102), Expect = 3e-04 Identities = 42/192 (21%), Positives = 81/192 (42%), Gaps = 37/192 (19%) Query: 236 QEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSRE-------------------- 275 +EK + + K R+ + ++EK +R +S S + Sbjct: 224 EEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPEN 283 Query: 276 ---HRRHRSRSMSRERKRRTRSKSRE-----------KRHRHRSRSSSRSRSRSHQRSRH 321 R+ ++ +ERK R R + RE +R +RS + + R +R R Sbjct: 284 RFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRT 343 Query: 322 SSRDRSRERSKRRSSKERFRDQDLASCDRDR-SSRDRSPR-DRDRKDKKRSYESANGRSE 379 SR RSR+R +R + +R Q++ R R SS +R + D+ ++ + + + R + Sbjct: 344 PSRSRSRDRFRRSETPPHWR-QEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVK 402 Query: 380 DRRSSEEREAGE 391 +R+ ++ R E Sbjct: 403 ERKITDHRNVSE 414 Score = 36.6 bits (83), Expect = 0.040 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 21/91 (23%) Query: 295 KSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRS------RERSKRRSSKERFRDQDLASC 348 K +KRH+ S SSS S SS D S E+SK+R K R Sbjct: 185 KEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHR--------- 235 Query: 349 DRDRSSRDRSPRDRDRKDKKRSYESANGRSE 379 ++SR +++K +K+S +SA+ SE Sbjct: 236 ---KNSRKHK---KEKKKRKKSKKSASSESE 260 >gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] Length = 715 Score = 80.9 bits (198), Expect = 2e-15 Identities = 60/181 (33%), Positives = 88/181 (48%), Gaps = 28/181 (15%) Query: 229 KRVVAEKQEKRNQERLKRREEREREEREKLRRSRSH--SKNPKRSRSREHRR-------H 279 ++ + + + +Q R + + + + R RR RSH S+NP + RS H R H Sbjct: 319 RKGILSQMGRHSQSRSHSKGKSQNQSRTP-RRGRSHNWSRNPSKERSHSHSRSSSKERDH 377 Query: 280 RSRSMSRERKRRTRSKSREKRHRH-RSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKE 338 R S R+ R++S S K+ H RSRS +++R RS RS + +RDRSR RS ++ Sbjct: 378 RGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKA--- 434 Query: 339 RFRDQDLASCDRDRS-------SRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGE 391 RD C R RS SR RSP + RS A RS R S+ER+ + Sbjct: 435 --RD-----CSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQ 487 Query: 392 I 392 + Sbjct: 488 L 488 Score = 77.8 bits (190), Expect = 2e-14 Identities = 55/156 (35%), Positives = 77/156 (49%), Gaps = 19/156 (12%) Query: 250 REREEREKLRRSRSHSKNPKRSRSREHRRHRS----------RSMSRER-KRRTRSKSRE 298 R+R + R HS+ S+ R+HRR RS RS S+ER RR+RS S+E Sbjct: 471 RDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKE 530 Query: 299 KRHR-----HRSRSSSRSRSRSHQRSRHSSRDRSRERSKRR---SSKERFRDQDLASCDR 350 ++ R ++ R S+SRS S +R SR S+ER +RR SKER R Q +S + Sbjct: 531 RQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEE 590 Query: 351 DRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEE 386 SR RSP + + R+ S R S+E Sbjct: 591 RDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKE 626 Score = 76.6 bits (187), Expect = 3e-14 Identities = 55/160 (34%), Positives = 78/160 (48%), Gaps = 6/160 (3%) Query: 234 EKQEKRNQERLKRREEREREEREKLR-RSRSHSKNPKRSRSREHRRHRSRSMSRER---K 289 ++ R++ K R+ K R RSRS S N R SR +++R SR R K Sbjct: 398 QRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNK 457 Query: 290 RRTRSKSRE-KRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASC 348 R S+SR + R RSRS S S+ R H + S++R RS+ S + + R +S Sbjct: 458 ARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSK 517 Query: 349 DRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 +RD R RSP ++ + RS RS+ R SEERE Sbjct: 518 ERDH-RRSRSPSKERQRRQSRSPNKERDRSQSRSPSEERE 556 Score = 72.0 bits (175), Expect = 9e-13 Identities = 49/155 (31%), Positives = 75/155 (48%), Gaps = 5/155 (3%) Query: 238 KRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKR-RTRSKS 296 K R R +ER+ R+ S+ RS S+E +R +SRS ++ER R ++RS S Sbjct: 493 KERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPS 552 Query: 297 REKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRD 356 E+ HR +SRS S+ R R RS R+R R R SS+ER + + + SR Sbjct: 553 EEREHR-QSRSPSKERDRRRWRSPSKERER---RQSRSSSEERDHSRSRSPNKQSGYSRP 608 Query: 357 RSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGE 391 R+ + R+ S+ R SS+E + + Sbjct: 609 RASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQ 643 Score = 70.9 bits (172), Expect = 2e-12 Identities = 61/184 (33%), Positives = 88/184 (47%), Gaps = 32/184 (17%) Query: 235 KQEKRNQERLKRREEREREEREKLR---RSRSHSKNPKRSRSR------EHRRHRSRSMS 285 + R++ K R+ K R RSRS K RSRSR +H R RS + + Sbjct: 411 RDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKA 470 Query: 286 RERKRRTRSKSREKRH---------RHRSRSSSRSRSRSHQRSRHSSRDRSRERSK---- 332 R+R R +RS S+E+ H R RS S S+ R ++SR SS++R RS+ Sbjct: 471 RDRSR-SRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSK 529 Query: 333 -------RRSSKERFRDQDLASCDRDRSSRDRSP-RDRDRKDKKRSYESANGRSEDRRSS 384 R +KER R Q + + + RSP ++RDR+ + RS R + R SS Sbjct: 530 ERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRR-RWRSPSKERERRQSRSSS 588 Query: 385 EERE 388 EER+ Sbjct: 589 EERD 592 Score = 70.9 bits (172), Expect = 2e-12 Identities = 53/160 (33%), Positives = 80/160 (50%), Gaps = 13/160 (8%) Query: 234 EKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKR-RT 292 E+ +R++ K R+ R+ K R RS S++P S REHR+ RS S R+R+R R+ Sbjct: 518 ERDHRRSRSPSKERQRRQSRSPNK-ERDRSQSRSP--SEEREHRQSRSPSKERDRRRWRS 574 Query: 293 RSKSREKR-------HRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDL 345 SK RE+R R SRS S ++ + R R SS++++ RS R SKE Q Sbjct: 575 PSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRS-RTPSKEGNHSQSR 633 Query: 346 ASCDRDRSSRDRSPRDRD-RKDKKRSYESANGRSEDRRSS 384 S S+ PR D ++ R+ + R+ + SS Sbjct: 634 TSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSS 673 Score = 70.5 bits (171), Expect = 3e-12 Identities = 54/162 (33%), Positives = 84/162 (51%), Gaps = 10/162 (6%) Query: 234 EKQEKRNQERLKRREER-EREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRER---K 289 E+ ++ K R+ R R++ RS+S S N +R SR +++R SR R K Sbjct: 362 ERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYK 421 Query: 290 RRTRSKSR---EKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLA 346 R RS+SR + R RSRS ++R RS RS + +RD SR RS + +++R R + Sbjct: 422 ARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNK-ARDRSRSRS-P 479 Query: 347 SCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 S +RD S ++RD + + RS + R SS+ER+ Sbjct: 480 SKERDHSQLGSPSKERDHR-RSRSPSKERQCRQSRSSSKERD 520 Score = 64.3 bits (155), Expect = 2e-10 Identities = 51/176 (28%), Positives = 78/176 (44%), Gaps = 7/176 (3%) Query: 220 EIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRH 279 E+ +++ + + + + + R R ++ R RSHS SR+R R Sbjct: 261 EMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRK 320 Query: 280 RSRS-MSRERKRRTRSKSR---EKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRS 335 S M R + R+ SK + + R R RS + SR+ S +RS SR S+ER R S Sbjct: 321 GILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGS 380 Query: 336 S---KERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 S KE R Q + + SR RSP + + RS A RS R ++ R+ Sbjct: 381 SSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARD 436 Score = 59.7 bits (143), Expect = 4e-09 Identities = 51/164 (31%), Positives = 77/164 (46%), Gaps = 18/164 (10%) Query: 222 REKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRS 281 R +E +R + K R ERE R+ S+ + RS S+E R +S Sbjct: 525 RSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQS 584 Query: 282 RSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFR 341 RS S ER +RS+S K+ + SR + S+ ++H RSR S++ + +S R SSKE Sbjct: 585 RSSSEERD-HSRSRSPNKQSGY-SRPRASSKEKAHSRSRTPSKEGNHSQS-RTSSKE--- 638 Query: 342 DQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSE 385 D +S+ RSP D KRS + S++R S+ Sbjct: 639 ------SDPSQSTVPRSP------DWKRSPTRTSSLSQNRTPSK 670 Score = 47.4 bits (111), Expect = 2e-05 Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 11/160 (6%) Query: 232 VAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRR 291 + K++ N R+ + + R +S+S SR + + + +RS + + Sbjct: 225 IPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRS-----RPQ 279 Query: 292 TRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSS--KERFRDQDLASCD 349 + S+SR R RSRS S+ R+ S RS R+ SR RS+ R + R S Sbjct: 280 SHSQSRSPR---RSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHS 336 Query: 350 RDRS-SRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388 + +S ++ R+PR + R+ S R SS+ER+ Sbjct: 337 KGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERD 376 Score = 43.5 bits (101), Expect = 3e-04 Identities = 40/136 (29%), Positives = 59/136 (43%), Gaps = 13/136 (9%) Query: 261 SRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSR 320 S S SK+ K + ++ +R S SR R + R+ SR S++S S R HQR Sbjct: 58 SPSSSKSTKSTSTKRAPSNRPSSRSRVRSK-ARTPSRVSTDTRTSKASKASDVRCHQRRG 116 Query: 321 HSSRDRSRERSKRRSSKERFRDQDLAS---------CDRDRSSRDRSPRDRDRKDKKRSY 371 SR R+ R RSSK R AS +SR R+P + + + +SY Sbjct: 117 THSRGRTPGRRGSRSSK---RSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSY 173 Query: 372 ESANGRSEDRRSSEER 387 + +R S+ R Sbjct: 174 GRPRTSNRERSDSQPR 189 Score = 36.6 bits (83), Expect = 0.040 Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 8/96 (8%) Query: 280 RSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKER 339 R+ MS + T+S S ++ +R S SR RS++ SR S+ R+ + SK + Sbjct: 53 RNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCH 112 Query: 340 FRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESAN 375 R R SR R+P R + KRS A+ Sbjct: 113 QR--------RGTHSRGRTPGRRGSRSSKRSPSRAS 140 Score = 33.1 bits (74), Expect = 0.44 Identities = 48/174 (27%), Positives = 75/174 (43%), Gaps = 59/174 (33%) Query: 222 REKLEELKRVVAEKQEKR-----NQERLKRREEREREEREKLRRSRSHSKNPKRSRSREH 276 +E+ R +E++E R ++ER +RR +ERE+ R+SRS S+ SRSR Sbjct: 541 KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERER-RQSRSSSEERDHSRSRSP 599 Query: 277 RRH----RSRSMSRERKR-RTRSKSREKRH------------------------RHRSRS 307 + R R+ S+E+ R+R+ S+E H R +R+ Sbjct: 600 NKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRT 659 Query: 308 SSRSRSRSHQR-SRHS-----------SRDRSR------------ERSKRRSSK 337 SS S++R+ + S HS S+D S+ ERS SSK Sbjct: 660 SSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSSK 713 >gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens] Length = 334 Score = 79.0 bits (193), Expect = 7e-15 Identities = 59/161 (36%), Positives = 86/161 (53%), Gaps = 17/161 (10%) Query: 248 EEREREEREKLRRSRSHSKNPKRSRSREH--RRHRSRSMSRERKRRTRSKSREKRHRHRS 305 E R + +++ RRS S S + R+ SR+ R+ RS+S S R + RS S ++R RHRS Sbjct: 11 ESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYDRRRRHRS 70 Query: 306 RSSS-----RSRSRSHQRSRHSS----RDRSRERSKRRSSKERFRDQDLASCDRDRSSRD 356 SSS R RSRS R R S R RS+ R++R S+ R R +S +R R Sbjct: 71 SSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSS-ERSSHRRT 129 Query: 357 RS-PRDRDRK----DKKRSYESANGRSEDRRSSEEREAGEI 392 RS RDR+R+ +KR E G+ ++ + + E+G I Sbjct: 130 RSRSRDRERRKGRDKEKREKEKDKGKDKELHNIKRGESGNI 170 Score = 72.8 bits (177), Expect = 5e-13 Identities = 58/161 (36%), Positives = 83/161 (51%), Gaps = 19/161 (11%) Query: 226 EELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRS-RSREH-----RRH 279 EE R +K+ +R + R ++ R+SRS S++ R + R H RRH Sbjct: 9 EEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQPRSHSYDRRRRH 68 Query: 280 RSRSMS----RERKRRTRSKSREKRHR-HRSRSSSRSRSRSHQRSRHSSRDRSRERSKRR 334 RS S S R ++ R+RS+ R K +R RSRS SR+R RS R R S RS ERS R Sbjct: 69 RSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTR-RSRSRPRLRSHSRSSERSSHR 127 Query: 335 SSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESAN 375 ++ R RD++ R RD+ R+++ KDK + E N Sbjct: 128 RTRSRSRDRE------RRKGRDKEKREKE-KDKGKDKELHN 161 Score = 68.2 bits (165), Expect = 1e-11 Identities = 51/169 (30%), Positives = 81/169 (47%), Gaps = 15/169 (8%) Query: 235 KQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRS 294 + + R+ R + + R + R S S S +R RSR R R +S R +R+RS Sbjct: 45 RSKSRSWSRDLQPRSHSYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSY---RVQRSRS 101 Query: 295 KSREKRHRHRSRSSSRSRSR---SHQRSRHSSRDR----SRERSKRRSSKERFRDQDLAS 347 KSR +R R R R S SRS SH+R+R SRDR R++ KR K++ +D++L + Sbjct: 102 KSRTRRSRSRPRLRSHSRSSERSSHRRTRSRSRDRERRKGRDKEKREKEKDKGKDKELHN 161 Query: 348 CDRDRSSR-----DRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGE 391 R S + P K + + A ++++ ++ER E Sbjct: 162 IKRGESGNIKAGLEHLPPAEQAKARLQLVLEAAAKADEALKAKERNEEE 210 Score = 58.9 bits (141), Expect = 8e-09 Identities = 50/147 (34%), Positives = 68/147 (46%), Gaps = 18/147 (12%) Query: 259 RRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRS-RSRSH- 316 RRS + + R ++HRR S S S + + +R K K R +SRS SR + RSH Sbjct: 3 RRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYSRKKGGRKS-RSKSRSWSRDLQPRSHS 61 Query: 317 --QRSRHSSRDRSRERSKRRSSKER-------FRDQDLASCDRDRSSRDRSP-RDRDRKD 366 +R RH S S S+R+ S+ R +R Q S R R SR R R R Sbjct: 62 YDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSS 121 Query: 367 KKRSYESANGRSEDR-----RSSEERE 388 ++ S+ RS DR R E+RE Sbjct: 122 ERSSHRRTRSRSRDRERRKGRDKEKRE 148 Score = 57.0 bits (136), Expect = 3e-08 Identities = 40/143 (27%), Positives = 61/143 (42%), Gaps = 1/143 (0%) Query: 243 RLKRREEREREEREKLRRSRSHSKN-PKRSRSREHRRHRSRSMSRERKRRTRSKSREKRH 301 R KR R R + R RS SK+ +RSRSR R SRS R RRTRS+SR++ Sbjct: 79 RRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSERSSHRRTRSRSRDRER 138 Query: 302 RHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRD 361 R R + + + + + E ++ E + A + D Sbjct: 139 RKGRDKEKREKEKDKGKDKELHNIKRGESGNIKAGLEHLPPAEQAKARLQLVLEAAAKAD 198 Query: 362 RDRKDKKRSYESANGRSEDRRSS 384 K K+R+ E A R E+ +++ Sbjct: 199 EALKAKERNEEEAKRRKEEDQAT 221 Score = 40.4 bits (93), Expect = 0.003 Identities = 30/139 (21%), Positives = 57/139 (41%), Gaps = 24/139 (17%) Query: 229 KRVVAEKQEKRNQERLKRREEREREEREKLR-RSRSHSKNPKRS-------RSREHRRHR 280 KR + + + R++R + R R + R R RSHS++ +RS RSR+ R + Sbjct: 81 KRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRSHSRSSERSSHRRTRSRSRDRERRK 140 Query: 281 SRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDR-------------- 326 R + K + + K +E + R S + H ++ R Sbjct: 141 GRDKEKREKEKDKGKDKELHNIKRGESGNIKAGLEHLPPAEQAKARLQLVLEAAAKADEA 200 Query: 327 --SRERSKRRSSKERFRDQ 343 ++ER++ + + + DQ Sbjct: 201 LKAKERNEEEAKRRKEEDQ 219 >gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] Length = 344 Score = 77.8 bits (190), Expect = 2e-14 Identities = 57/158 (36%), Positives = 76/158 (48%), Gaps = 17/158 (10%) Query: 245 KRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKR-RTRSKSREKRHRH 303 +R R RRSRS S+ RSRSR + RSRS SR + R R+RSK R+ R + Sbjct: 188 RRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKS 247 Query: 304 RSRSSSRSRSRSHQRSRHSSR-DRSRERSKRRSSKERFRDQDLASCDRDRS--------- 353 +S+ S S SH RSR ++SR RS+ RS KE + D+ S R RS Sbjct: 248 KSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKG-DIKSKSRSRSQSRSNSPLP 306 Query: 354 -----SRDRSPRDRDRKDKKRSYESANGRSEDRRSSEE 386 +R SP + + RS + RS R SS + Sbjct: 307 VPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344 Score = 73.2 bits (178), Expect = 4e-13 Identities = 67/180 (37%), Positives = 94/180 (52%), Gaps = 17/180 (9%) Query: 207 ADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSK 266 AD + + G IE R ++KR + +K + + R R E++ + RS+S Sbjct: 139 ADAHKERTNEGVIEFRS-YSDMKRAL----DKLDGTEINGRNIRLIEDKPRTSHRRSYSG 193 Query: 267 NPKRSRSREHRRHRSRSMSRERKRRTRSKSREK-RHRHRSRSSSRSRSRSHQRSRHSSRD 325 + RSRSR RR RSRS R R+RS+S K R R RSRS RSRSRS R + S+ Sbjct: 194 S--RSRSRSRRRSRSRS---RRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGR-KSRSKS 247 Query: 326 RSRERSKRRS-SKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSS 384 +S+ +S R S S R R +D R R SR RSP++ + D K + RS+ R +S Sbjct: 248 KSKPKSDRGSHSHSRSRSKDEYEKSRSR-SRSRSPKENGKGDIK---SKSRSRSQSRSNS 303 Score = 62.8 bits (151), Expect = 5e-10 Identities = 44/124 (35%), Positives = 59/124 (47%), Gaps = 20/124 (16%) Query: 239 RNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSRE 298 +++ R + R + R K R+SRS SK+ +S H RSRS K R+RS+SR Sbjct: 221 KSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRS 280 Query: 299 KRHRHRSRSSSRSRSRSHQRS-------------------RHSSRDRSRERSKRRS-SKE 338 + + S+SRSRS RS R +SR RSR RSK RS S+ Sbjct: 281 PKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRS 340 Query: 339 RFRD 342 RD Sbjct: 341 SSRD 344 >gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] Length = 330 Score = 77.8 bits (190), Expect = 2e-14 Identities = 53/149 (35%), Positives = 70/149 (46%), Gaps = 11/149 (7%) Query: 233 AEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRT 292 + K++ + R K R R S S S++ RSRS + RSRS SRER R Sbjct: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSR 252 Query: 293 RSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDR 352 SKSR HR SS R RS S S SS +R+R+RS+ RSS R + R Sbjct: 253 GSKSRSSSRSHRGSSSPRKRSYS---SSSSSPERNRKRSRSRSSSSGDR--------KKR 301 Query: 353 SSRDRSPRDRDRKDKKRSYESANGRSEDR 381 +R RSP R R S+ + S+ + Sbjct: 302 RTRSRSPERRHRSSSGSSHSGSRSSSKKK 330 Score = 77.0 bits (188), Expect = 3e-14 Identities = 58/186 (31%), Positives = 94/186 (50%), Gaps = 4/186 (2%) Query: 198 GLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREK 257 G +D R + GK +G I +++E+ + E+ E + + K E+ + ++ + Sbjct: 122 GEYDEFGRKKKKYRGKA-VGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADL 180 Query: 258 LRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQ 317 + + S+ ++ + +RR RS+S S + +RS S R RSRS SRS S S Sbjct: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSS-RSRSRSRSRSSSSSQS 239 Query: 318 RSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGR 377 RSR SSR+RSR R + S R + R SS SP +R+RK + RS S++G Sbjct: 240 RSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSP-ERNRK-RSRSRSSSSGD 297 Query: 378 SEDRRS 383 + RR+ Sbjct: 298 RKKRRT 303 Score = 68.6 bits (166), Expect = 1e-11 Identities = 66/184 (35%), Positives = 91/184 (49%), Gaps = 24/184 (13%) Query: 220 EIREKLEELKRVVAEKQEKRNQERLKR-----REEREREEREKLRRSRSHSKNP---KRS 271 E ++ E+L + ++ E + L + EE + +++ RRSRS S++ S Sbjct: 156 EEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSS 215 Query: 272 RSREHRRHRSRSMSRER-----KRRTRSKSREKRHRHRSR-SSSRSRSRSHQRSRHSSRD 325 RS RSRS SR R + R+RS SRE R RSR S SRS SRSH R SS Sbjct: 216 RSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRE---RSRSRGSKSRSSSRSH---RGSSSP 269 Query: 326 RSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSED-RRSS 384 R R S SS ER R + S R SS DR R + +R + S++G S RSS Sbjct: 270 RKRSYSSSSSSPERNRKR---SRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326 Query: 385 EERE 388 +++ Sbjct: 327 SKKK 330 Score = 38.9 bits (89), Expect = 0.008 Identities = 44/191 (23%), Positives = 73/191 (38%), Gaps = 15/191 (7%) Query: 109 AETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKRE 168 +E +EE E +K ++L+E+ + A + + + + EE ++R+K R Sbjct: 153 SEGEEEDEDEDLSK----YKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208 Query: 169 AEE--VYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLE 226 + R+S P+SS + + R S+ + R + G K R Sbjct: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268 Query: 227 ELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSR 286 KR + + R + R K RR+RS S RRHRS S S Sbjct: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRS---------PERRHRSSSGSS 319 Query: 287 ERKRRTRSKSR 297 R+ SK + Sbjct: 320 HSGSRSSSKKK 330 >gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] Length = 320 Score = 77.4 bits (189), Expect = 2e-14 Identities = 62/198 (31%), Positives = 98/198 (49%), Gaps = 8/198 (4%) Query: 198 GLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREK 257 G +D R + GK +G I +++E+ + E+ E + + K E+ + ++ + Sbjct: 122 GEYDEFGRKKKKYRGKA-VGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADL 180 Query: 258 LRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQ 317 + + S+ ++ + +RR RS+S S + +RS S R RSRS SRS S S Sbjct: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSS-RSRSRSRSRSSSSSQS 239 Query: 318 RSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGR 377 RSR SSR+RSR R + S R + R SS SP +R+RK + RS S++G Sbjct: 240 RSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSP-ERNRK-RSRSRSSSSGD 297 Query: 378 SEDR----RSSEEREAGE 391 + R RS E + GE Sbjct: 298 RKKRRTRSRSPESQVIGE 315 Score = 30.8 bits (68), Expect = 2.2 Identities = 34/159 (21%), Positives = 61/159 (38%), Gaps = 6/159 (3%) Query: 109 AETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKRE 168 +E +EE E +K ++L+E+ + A + + + + EE ++R+K R Sbjct: 153 SEGEEEDEDEDLSK----YKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208 Query: 169 AEE--VYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLE 226 + R+S P+SS + + R S+ + R + G K R Sbjct: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSS 268 Query: 227 ELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHS 265 KR + + R + R K RR+RS S Sbjct: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRS 307 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.127 0.345 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,390,694 Number of Sequences: 37866 Number of extensions: 608906 Number of successful extensions: 31621 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 659 Number of HSP's successfully gapped in prelim test: 900 Number of HSP's that attempted gapping in prelim test: 7086 Number of HSP's gapped (non-prelim): 8765 length of query: 392 length of database: 18,247,518 effective HSP length: 104 effective length of query: 288 effective length of database: 14,309,454 effective search space: 4121122752 effective search space used: 4121122752 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.