Guide to the Human Genome
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Search of human proteins with 239745731

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239745731 PREDICTED: TBC1 domain family, member 27 [Homo
sapiens]
         (339 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239745731 PREDICTED: TBC1 domain family, member 27 [Homo sapi...   690   0.0  
gi|239756746 PREDICTED: TBC1 domain family, member 27 [Homo sapi...   684   0.0  
gi|239751241 PREDICTED: TBC1 domain family, member 27 [Homo sapi...   481   e-136
gi|109638751 ubiquitin specific protease 6 [Homo sapiens]             135   4e-32
gi|226693407 TBC1 domain family, member 3H [Homo sapiens]             130   2e-30
gi|183583563 TBC1 domain family, member 3D [Homo sapiens]             130   2e-30
gi|157502205 TBC1 domain family, member 3G [Homo sapiens]             130   2e-30
gi|14149985 TBC1 domain family, member 3F [Homo sapiens]              129   3e-30
gi|183583565 TBC1 domain family, member 3 [Homo sapiens]              129   3e-30
gi|183583567 TBC1 domain family, member 3E [Homo sapiens]             129   3e-30
gi|90577185 TBC1 domain family member 3C [Homo sapiens]               127   2e-29
gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]              125   5e-29
gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]            125   5e-29
gi|149999613 TBC1 domain family, member 3B [Homo sapiens]             125   5e-29
gi|7661586 TBC1 domain family, member 29 [Homo sapiens]                59   5e-09
gi|151108489 TBC1 domain family, member 28 [Homo sapiens]              53   3e-07
gi|239756750 PREDICTED: similar to TBC1 domain family, member 28...    49   8e-06
gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens]    48   1e-05
gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens]    48   1e-05
gi|148235002 TBC1 domain family, member 26 [Homo sapiens]              47   2e-05
gi|239756926 PREDICTED: similar to TBC1 domain family, member 3 ...    46   4e-05
gi|239745813 PREDICTED: hypothetical protein XP_002343595 [Homo ...    46   4e-05
gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens]    42   0.001
gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens]    42   0.001
gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens]    42   0.001
gi|239756790 PREDICTED: similar to hCG1991532 [Homo sapiens]           41   0.001
gi|29648315 small G protein signaling modulator 3 [Homo sapiens]       39   0.005
gi|222352143 TBC1 domain family, member 2 [Homo sapiens]               38   0.011
gi|148806902 TBC1 domain family, member 12 [Homo sapiens]              35   0.073
gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]     35   0.13 

>gi|239745731 PREDICTED: TBC1 domain family, member 27 [Homo
           sapiens]
          Length = 339

 Score =  690 bits (1781), Expect = 0.0
 Identities = 339/339 (100%), Positives = 339/339 (100%)

Query: 1   MEMDEHPDILPTQGQGNIIITKYEQGPKAQDPASMGRCRRPGSSANSIMAHLTAKEVGYH 60
           MEMDEHPDILPTQGQGNIIITKYEQGPKAQDPASMGRCRRPGSSANSIMAHLTAKEVGYH
Sbjct: 1   MEMDEHPDILPTQGQGNIIITKYEQGPKAQDPASMGRCRRPGSSANSIMAHLTAKEVGYH 60

Query: 61  RDLSRNTAVLLYLPEEDAFWVAGSAAGRPNTAQLRKLLSHQEQVLHKSFPKIMRQLGKEG 120
           RDLSRNTAVLLYLPEEDAFWVAGSAAGRPNTAQLRKLLSHQEQVLHKSFPKIMRQLGKEG
Sbjct: 61  RDLSRNTAVLLYLPEEDAFWVAGSAAGRPNTAQLRKLLSHQEQVLHKSFPKIMRQLGKEG 120

Query: 121 LCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHASFKIHREHLMKLSWS 180
           LCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHASFKIHREHLMKLSWS
Sbjct: 121 LCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHASFKIHREHLMKLSWS 180

Query: 181 TVWEFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPESLLQNAHCCTIAWGLQSK 240
           TVWEFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPESLLQNAHCCTIAWGLQSK
Sbjct: 181 TVWEFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPESLLQNAHCCTIAWGLQSK 240

Query: 241 AGKNSCTSRASGDFRAHPRTESLMXHLPAQKRRNKGQRTASKSWKEMKYPPLGVAIGKES 300
           AGKNSCTSRASGDFRAHPRTESLM HLPAQKRRNKGQRTASKSWKEMKYPPLGVAIGKES
Sbjct: 241 AGKNSCTSRASGDFRAHPRTESLMXHLPAQKRRNKGQRTASKSWKEMKYPPLGVAIGKES 300

Query: 301 CPITDNELHFLERRPLSPKLVQALGVAGQCLAVQLYLRT 339
           CPITDNELHFLERRPLSPKLVQALGVAGQCLAVQLYLRT
Sbjct: 301 CPITDNELHFLERRPLSPKLVQALGVAGQCLAVQLYLRT 339


>gi|239756746 PREDICTED: TBC1 domain family, member 27 [Homo
           sapiens]
          Length = 339

 Score =  684 bits (1765), Expect = 0.0
 Identities = 337/339 (99%), Positives = 337/339 (99%)

Query: 1   MEMDEHPDILPTQGQGNIIITKYEQGPKAQDPASMGRCRRPGSSANSIMAHLTAKEVGYH 60
           MEMDEHPDILPTQGQGNIIITKYEQGPKAQDPASMGRCRRPGSSANSIMAHLTAKEVGYH
Sbjct: 1   MEMDEHPDILPTQGQGNIIITKYEQGPKAQDPASMGRCRRPGSSANSIMAHLTAKEVGYH 60

Query: 61  RDLSRNTAVLLYLPEEDAFWVAGSAAGRPNTAQLRKLLSHQEQVLHKSFPKIMRQLGKEG 120
           RDLSRNTAVLLYLPEEDAFWVAGSAAGRPNTAQLRKLLSHQEQVLHKSFPKIMRQLGKEG
Sbjct: 61  RDLSRNTAVLLYLPEEDAFWVAGSAAGRPNTAQLRKLLSHQEQVLHKSFPKIMRQLGKEG 120

Query: 121 LCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHASFKIHREHLMKLSWS 180
           LCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHASFKIHREHLMKLSWS
Sbjct: 121 LCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHASFKIHREHLMKLSWS 180

Query: 181 TVWEFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPESLLQNAHCCTIAWGLQSK 240
           TVWEFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPESLLQNAH CTIAWGLQSK
Sbjct: 181 TVWEFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPESLLQNAHRCTIAWGLQSK 240

Query: 241 AGKNSCTSRASGDFRAHPRTESLMXHLPAQKRRNKGQRTASKSWKEMKYPPLGVAIGKES 300
           AGKNSCTSRASGDFRAHPRTESLM HLPAQKRRNKGQRTASKSWKEMKYPPLG AIGKES
Sbjct: 241 AGKNSCTSRASGDFRAHPRTESLMXHLPAQKRRNKGQRTASKSWKEMKYPPLGAAIGKES 300

Query: 301 CPITDNELHFLERRPLSPKLVQALGVAGQCLAVQLYLRT 339
           CPITDNELHFLERRPLSPKLVQALGVAGQCLAVQLYLRT
Sbjct: 301 CPITDNELHFLERRPLSPKLVQALGVAGQCLAVQLYLRT 339


>gi|239751241 PREDICTED: TBC1 domain family, member 27 [Homo
           sapiens]
          Length = 617

 Score =  481 bits (1238), Expect = e-136
 Identities = 235/237 (99%), Positives = 236/237 (99%)

Query: 56  EVGYHRDLSRNTAVLLYLPEEDAFWVAGSAAGRPNTAQLRKLLSHQEQVLHKSFPKIMRQ 115
           EVGYHRDLSRNTAVLLYLPEEDAFWVAGSAAGRPNTAQLRKLLSHQEQVLHKSFPKIMRQ
Sbjct: 186 EVGYHRDLSRNTAVLLYLPEEDAFWVAGSAAGRPNTAQLRKLLSHQEQVLHKSFPKIMRQ 245

Query: 116 LGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHASFKIHREHLM 175
           LGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHASFKIHREHLM
Sbjct: 246 LGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHASFKIHREHLM 305

Query: 176 KLSWSTVWEFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPESLLQNAHCCTIAW 235
           KLSWSTVWEFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPESLLQNAHCCTIAW
Sbjct: 306 KLSWSTVWEFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPESLLQNAHCCTIAW 365

Query: 236 GLQSKAGKNSCTSRASGDFRAHPRTESLMXHLPAQKRRNKGQRTASKSWKEMKYPPL 292
           GLQSKAGKNSCTSRASGDFRAHPRTESLM HLPAQKRRNKGQRTASKSWKEMKY P+
Sbjct: 366 GLQSKAGKNSCTSRASGDFRAHPRTESLMXHLPAQKRRNKGQRTASKSWKEMKYQPV 422



 Score =  103 bits (258), Expect = 2e-22
 Identities = 50/55 (90%), Positives = 51/55 (92%)

Query: 285 KEMKYPPLGVAIGKESCPITDNELHFLERRPLSPKLVQALGVAGQCLAVQLYLRT 339
           +  K PPLG AIGKESCPITDNELHFLERRPLSPKLVQALGVAGQCLAVQLYLRT
Sbjct: 563 QSFKDPPLGAAIGKESCPITDNELHFLERRPLSPKLVQALGVAGQCLAVQLYLRT 617



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 29/39 (74%), Positives = 29/39 (74%), Gaps = 7/39 (17%)

Query: 1  MEMDEHPDILPTQGQGNIIITKYEQ-------GPKAQDP 32
          MEMDEHPDILPTQGQGNIIITKYEQ        P  QDP
Sbjct: 37 MEMDEHPDILPTQGQGNIIITKYEQDHRVKTGSPCRQDP 75


>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
          Length = 1406

 Score =  135 bits (341), Expect = 4e-32
 Identities = 82/178 (46%), Positives = 110/178 (61%), Gaps = 12/178 (6%)

Query: 56  EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 104
           EVGY RDLS  TA+ LLYLPEEDAFW  V   A+ R        PN   ++ L   QE V
Sbjct: 182 EVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEHV 241

Query: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
           + KS PK M    KEGLC + + L  LL+  +DG S GLTLRLWDV ++EGEQVL  +  
Sbjct: 242 VPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPITS 301

Query: 165 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSP 221
            + K+ ++ LMK S   +W   + +   +WA+ D++VL++L+ S K+LT+K  DLP P
Sbjct: 302 IALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPP 359


>gi|226693407 TBC1 domain family, member 3H [Homo sapiens]
          Length = 549

 Score =  130 bits (326), Expect = 2e-30
 Identities = 88/215 (40%), Positives = 118/215 (54%), Gaps = 18/215 (8%)

Query: 56  EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 104
           EVGY RDLS   A+ LLYLPEEDAFW  V   A+ R        PN   ++ L   QE V
Sbjct: 183 EVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHV 242

Query: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
           +  S PK M    K+ LC + S L  L++  +DG S GLTLRLWDV ++EGEQ L  +  
Sbjct: 243 VATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITR 302

Query: 165 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPES 223
            +FK+ ++ L K S    W  F  R   +WA ++++VL++L+ SMK+LT+K  DLP P  
Sbjct: 303 IAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAK 362

Query: 224 LLQNAHCCTIAWGLQSKAGKNSCTSRASGDFRAHP 258
             Q +          S+ GK  C     GD +A P
Sbjct: 363 PEQGSSASRPV--PASRGGKTLC----KGDRQAPP 391


>gi|183583563 TBC1 domain family, member 3D [Homo sapiens]
          Length = 549

 Score =  130 bits (326), Expect = 2e-30
 Identities = 88/215 (40%), Positives = 118/215 (54%), Gaps = 18/215 (8%)

Query: 56  EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 104
           EVGY RDLS   A+ LLYLPEEDAFW  V   A+ R        PN   ++ L   QE V
Sbjct: 183 EVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHV 242

Query: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
           +  S PK M    K+ LC + S L  L++  +DG S GLTLRLWDV ++EGEQ L  +  
Sbjct: 243 VATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITR 302

Query: 165 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPES 223
            +FK+ ++ L K S    W  F  R   +WA ++++VL++L+ SMK+LT+K  DLP P  
Sbjct: 303 IAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAK 362

Query: 224 LLQNAHCCTIAWGLQSKAGKNSCTSRASGDFRAHP 258
             Q +          S+ GK  C     GD +A P
Sbjct: 363 PEQGSSASRPV--PASRGGKTLC----KGDRQAPP 391


>gi|157502205 TBC1 domain family, member 3G [Homo sapiens]
          Length = 549

 Score =  130 bits (326), Expect = 2e-30
 Identities = 88/215 (40%), Positives = 118/215 (54%), Gaps = 18/215 (8%)

Query: 56  EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 104
           EVGY RDLS   A+ LLYLPEEDAFW  V   A+ R        PN   ++ L   QE V
Sbjct: 183 EVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHV 242

Query: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
           +  S PK M    K+ LC + S L  L++  +DG S GLTLRLWDV ++EGEQ L  +  
Sbjct: 243 VATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITR 302

Query: 165 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPES 223
            +FK+ ++ L K S    W  F  R   +WA ++++VL++L+ SMK+LT+K  DLP P  
Sbjct: 303 IAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAK 362

Query: 224 LLQNAHCCTIAWGLQSKAGKNSCTSRASGDFRAHP 258
             Q +          S+ GK  C     GD +A P
Sbjct: 363 PEQGSSASRPV--PASRGGKTLC----KGDRQAPP 391


>gi|14149985 TBC1 domain family, member 3F [Homo sapiens]
          Length = 549

 Score =  129 bits (325), Expect = 3e-30
 Identities = 88/215 (40%), Positives = 118/215 (54%), Gaps = 18/215 (8%)

Query: 56  EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 104
           EVGY RDLS   A+ LLYLPEEDAFW  V   A+ R        PN   ++ L   QE V
Sbjct: 183 EVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHV 242

Query: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
           +  S PK M    K+ LC + S L  L++  +DG S GLTLRLWDV ++EGEQ L  +  
Sbjct: 243 VATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITR 302

Query: 165 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPES 223
            +FK+ ++ L K S    W  F  R   +WA ++++VL++L+ SMK+LT+K  DLP P  
Sbjct: 303 IAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAK 362

Query: 224 LLQNAHCCTIAWGLQSKAGKNSCTSRASGDFRAHP 258
             Q +          S+ GK  C     GD +A P
Sbjct: 363 PEQGSSASRPV--PASRGGKTLC----KGDRQAPP 391


>gi|183583565 TBC1 domain family, member 3 [Homo sapiens]
          Length = 549

 Score =  129 bits (325), Expect = 3e-30
 Identities = 88/215 (40%), Positives = 118/215 (54%), Gaps = 18/215 (8%)

Query: 56  EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 104
           EVGY RDLS   A+ LLYLPEEDAFW  V   A+ R        PN   ++ L   QE V
Sbjct: 183 EVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHV 242

Query: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
           +  S PK M    K+ LC + S L  L++  +DG S GLTLRLWDV ++EGEQ L  +  
Sbjct: 243 VATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITR 302

Query: 165 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPES 223
            +FK+ ++ L K S    W  F  R   +WA ++++VL++L+ SMK+LT+K  DLP P  
Sbjct: 303 IAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAK 362

Query: 224 LLQNAHCCTIAWGLQSKAGKNSCTSRASGDFRAHP 258
             Q +          S+ GK  C     GD +A P
Sbjct: 363 PEQGSSASRPV--PASRGGKTLC----KGDRQAPP 391


>gi|183583567 TBC1 domain family, member 3E [Homo sapiens]
          Length = 549

 Score =  129 bits (325), Expect = 3e-30
 Identities = 88/215 (40%), Positives = 118/215 (54%), Gaps = 18/215 (8%)

Query: 56  EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 104
           EVGY RDLS   A+ LLYLPEEDAFW  V   A+ R        PN   ++ L   QE V
Sbjct: 183 EVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHV 242

Query: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
           +  S PK M    K+ LC + S L  L++  +DG S GLTLRLWDV ++EGEQ L  +  
Sbjct: 243 VATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITR 302

Query: 165 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPES 223
            +FK+ ++ L K S    W  F  R   +WA ++++VL++L+ SMK+LT+K  DLP P  
Sbjct: 303 IAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAK 362

Query: 224 LLQNAHCCTIAWGLQSKAGKNSCTSRASGDFRAHP 258
             Q +          S+ GK  C     GD +A P
Sbjct: 363 PEQGSSASRPV--PASRGGKTLC----KGDRQAPP 391


>gi|90577185 TBC1 domain family member 3C [Homo sapiens]
          Length = 549

 Score =  127 bits (318), Expect = 2e-29
 Identities = 87/215 (40%), Positives = 117/215 (54%), Gaps = 18/215 (8%)

Query: 56  EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 104
           EVGY RDLS   A+ LLYLPEEDAFW  V   A+ R        PN   ++ L   QE V
Sbjct: 183 EVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHV 242

Query: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
           +  S  K M    K+ LC + S L  L++  +DG S GLTLRLWDV ++EGEQ L  +  
Sbjct: 243 VATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITR 302

Query: 165 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPES 223
            +FK+ ++ L K S    W  F  R   +WA ++++VL++L+ SMK+LT+K  DLP P  
Sbjct: 303 IAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAK 362

Query: 224 LLQNAHCCTIAWGLQSKAGKNSCTSRASGDFRAHP 258
             Q +          S+ GK  C     GD +A P
Sbjct: 363 PEQGSSASRPV--PASRGGKTLC----KGDRQAPP 391


>gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]
          Length = 828

 Score =  125 bits (314), Expect = 5e-29
 Identities = 93/283 (32%), Positives = 136/283 (48%), Gaps = 25/283 (8%)

Query: 56  EVGYHRDLSRNTAVLL-YLPEEDAFWVAGSAAGRPNTA----------QLRKLLSHQEQV 104
           EVGY + +S+ TA+LL Y+ EEDAFW        P  A          +L +   H E++
Sbjct: 182 EVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKI 241

Query: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
           L+K   K+ + L  + +      +    QCFLD   F L LR+WD+ I EGE+VLTAM++
Sbjct: 242 LNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSY 301

Query: 165 ASFKIHREHLMKLSWSTVWE-FQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPS--- 220
              K+H++HLMKLS   + E FQE L++ +  ED+ V+  LQ SM EL +   DLP    
Sbjct: 302 TILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGK 361

Query: 221 ----PESLLQNAHCCTIAWGLQSKAGKNSCTSRASGDFRAHPRTESLMXHLPAQKRRNKG 276
               P+  L        +WG+   +       R S    A  R ES   H   +   +  
Sbjct: 362 EDEYPKKPLGQLPPELQSWGVHHLSNGQRSVGRPSP--LASGRRESGAPHRRHEHSPHPQ 419

Query: 277 QRTASKSWKEMKYPPLGVAIGKESCPITDNELHFLERRPLSPK 319
            RT +    E   PP   ++ +ES  + D E  F  + P  P+
Sbjct: 420 SRTGT---PERAQPPRRKSVEEESKKLKD-EADFQRKLPSGPQ 458


>gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]
          Length = 845

 Score =  125 bits (314), Expect = 5e-29
 Identities = 93/283 (32%), Positives = 136/283 (48%), Gaps = 25/283 (8%)

Query: 56  EVGYHRDLSRNTAVLL-YLPEEDAFWVAGSAAGRPNTA----------QLRKLLSHQEQV 104
           EVGY + +S+ TA+LL Y+ EEDAFW        P  A          +L +   H E++
Sbjct: 199 EVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKI 258

Query: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
           L+K   K+ + L  + +      +    QCFLD   F L LR+WD+ I EGE+VLTAM++
Sbjct: 259 LNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSY 318

Query: 165 ASFKIHREHLMKLSWSTVWE-FQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPS--- 220
              K+H++HLMKLS   + E FQE L++ +  ED+ V+  LQ SM EL +   DLP    
Sbjct: 319 TILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGK 378

Query: 221 ----PESLLQNAHCCTIAWGLQSKAGKNSCTSRASGDFRAHPRTESLMXHLPAQKRRNKG 276
               P+  L        +WG+   +       R S    A  R ES   H   +   +  
Sbjct: 379 EDEYPKKPLGQLPPELQSWGVHHLSNGQRSVGRPSP--LASGRRESGAPHRRHEHSPHPQ 436

Query: 277 QRTASKSWKEMKYPPLGVAIGKESCPITDNELHFLERRPLSPK 319
            RT +    E   PP   ++ +ES  + D E  F  + P  P+
Sbjct: 437 SRTGT---PERAQPPRRKSVEEESKKLKD-EADFQRKLPSGPQ 475


>gi|149999613 TBC1 domain family, member 3B [Homo sapiens]
          Length = 549

 Score =  125 bits (314), Expect = 5e-29
 Identities = 86/215 (40%), Positives = 116/215 (53%), Gaps = 18/215 (8%)

Query: 56  EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGR--------PNTAQLRKLLSHQEQV 104
           EVGY RDLS   A+ LLY PEEDAFW  V   A+ R        PN   ++ L   QE V
Sbjct: 183 EVGYCRDLSHIAALFLLYFPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHV 242

Query: 105 LHKSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
           +  S  K M    K+ LC + S L  L++  +DG S GLTLRLWDV ++EGEQ L  +  
Sbjct: 243 VATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITR 302

Query: 165 ASFKIHREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPES 223
            +FK+ ++ L K S    W  F  R   +WA ++++VL++L+ SMK+LT+K  DLP P  
Sbjct: 303 IAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAK 362

Query: 224 LLQNAHCCTIAWGLQSKAGKNSCTSRASGDFRAHP 258
             Q +          S+ GK  C     GD +A P
Sbjct: 363 PEQGSSASRPV--PASRGGKTLC----KGDRQAPP 391


>gi|7661586 TBC1 domain family, member 29 [Homo sapiens]
          Length = 150

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 32/70 (45%), Positives = 42/70 (60%), Gaps = 3/70 (4%)

Query: 113 MRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHASFKIHR- 171
           M  L KEGLC +GS  + LL+   DG S GLT  LWD+ +LEGEQ+L  +   +FK+ R 
Sbjct: 1   MGHLDKEGLCTQGSSFSWLLRVLNDGISLGLTPCLWDMYLLEGEQMLMLITSIAFKVQRS 60

Query: 172 --EHLMKLSW 179
             E   K +W
Sbjct: 61  LYEETNKETW 70


>gi|151108489 TBC1 domain family, member 28 [Homo sapiens]
          Length = 210

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 25/36 (69%), Positives = 27/36 (75%)

Query: 1  MEMDEHPDILPTQGQGNIIITKYEQGPKAQDPASMG 36
          MEMDE PD LP QGQGNIIITKYEQG +A     +G
Sbjct: 1  MEMDEDPDNLPAQGQGNIIITKYEQGHRAGAAVDLG 36


>gi|239756750 PREDICTED: similar to TBC1 domain family, member 28
          [Homo sapiens]
          Length = 234

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 31/75 (41%), Positives = 37/75 (49%), Gaps = 8/75 (10%)

Query: 1  MEMDEHPDILPTQGQGNIIITKYEQGPKAQDPASMGR--------CRRPGSSANSIMAHL 52
          MEMD  P  LP QGQGNIIITKYEQG +A     +G             G      + H+
Sbjct: 25 MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPHV 84

Query: 53 TAKEVGYHRDLSRNT 67
          +A EV   R  S+ T
Sbjct: 85 SALEVKQRRKESKRT 99


>gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens]
          Length = 963

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 38/133 (28%), Positives = 63/133 (47%), Gaps = 13/133 (9%)

Query: 56  EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGRPNTAQLRKLLSHQ------EQVLH 106
           ++GY + L+R  AV LLYL +EDAFW  V       P     + LL  Q        ++ 
Sbjct: 748 DIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMS 807

Query: 107 KSFPKIMRQLGKEGLCIEGSMLTR--LLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
           +  P++      E   ++ +++T    L  F+D     +  ++WD  + EG +V+   A 
Sbjct: 808 EKLPRLHGHF--EQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFAL 865

Query: 165 ASFKIHREHLMKL 177
           A FK   E ++KL
Sbjct: 866 ALFKYKEEEILKL 878


>gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens]
          Length = 914

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 38/133 (28%), Positives = 63/133 (47%), Gaps = 13/133 (9%)

Query: 56  EVGYHRDLSRNTAV-LLYLPEEDAFW--VAGSAAGRPNTAQLRKLLSHQ------EQVLH 106
           ++GY + L+R  AV LLYL +EDAFW  V       P     + LL  Q        ++ 
Sbjct: 748 DIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMS 807

Query: 107 KSFPKIMRQLGKEGLCIEGSMLTR--LLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAH 164
           +  P++      E   ++ +++T    L  F+D     +  ++WD  + EG +V+   A 
Sbjct: 808 EKLPRLHGHF--EQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFAL 865

Query: 165 ASFKIHREHLMKL 177
           A FK   E ++KL
Sbjct: 866 ALFKYKEEEILKL 878


>gi|148235002 TBC1 domain family, member 26 [Homo sapiens]
          Length = 250

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 23/36 (63%), Positives = 25/36 (69%)

Query: 1  MEMDEHPDILPTQGQGNIIITKYEQGPKAQDPASMG 36
          MEMD  P  LP QGQGNIIITKYEQG +A     +G
Sbjct: 1  MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLG 36



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 22/26 (84%), Positives = 23/26 (88%), Gaps = 1/26 (3%)

Query: 56  EVGYHRDLSRNTAVLLY-LPEEDAFW 80
           EVGYHRDLSR TA+LL  LPEEDAFW
Sbjct: 183 EVGYHRDLSRITAILLLCLPEEDAFW 208


>gi|239756926 PREDICTED: similar to TBC1 domain family, member 3
           [Homo sapiens]
          Length = 424

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 74/270 (27%), Positives = 115/270 (42%), Gaps = 51/270 (18%)

Query: 19  IITKYEQGPKAQDPASMGRCRRPGSSANSIMAH-----------LTAKEVGY-HRDLSRN 66
           II KYE+G +A  P   G   +P  S N+ + H           LTA+EV    R++SR 
Sbjct: 18  IIMKYEKGHRAGLPEDKGP--KPFGSYNNNIDHFGMQHETELPPLTAREVKQIRREISRK 75

Query: 67  TAVLLYLPEEDAF-----WVAGSAAGRPNTAQ--LRKLLSHQEQVLHKSFPK--IMRQLG 117
           +  +  L E D +      +  +  G P   +  +  +L + E++  K+  +  IM++ G
Sbjct: 76  SKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRYQIMKEKG 135

Query: 118 KEG--------LCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHASFKI 169
           K          L + G++   +   F D   +G  L     L + G         A  K 
Sbjct: 136 KRSSEHIQQMDLDVSGTLRRHIF--FRD--RYGTNL-----LCISGRWGGPQKDPAPPK- 185

Query: 170 HREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPESLLQNA 228
               L K S    W  F  R   +WA +D++VL++L+ SMK+LT+K  DLP P    Q +
Sbjct: 186 ---RLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGS 242

Query: 229 HCCTIAWGLQSKAGKNSCTSRASGDFRAHP 258
                     S+ GK  C     GD +A P
Sbjct: 243 SASRPV--PASRGGKTLC----KGDRQAPP 266


>gi|239745813 PREDICTED: hypothetical protein XP_002343595 [Homo
           sapiens]
          Length = 279

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 23/52 (44%), Positives = 34/52 (65%), Gaps = 1/52 (1%)

Query: 172 EHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPE 222
           +HLMK S S +W  FQ++  Q+WAL+ ++VLR+LQ S+    K+    P PE
Sbjct: 110 KHLMKASRSGLWARFQDQFPQTWALDSDAVLRHLQASVLSKPKQGSSAPRPE 161


>gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens]
          Length = 413

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 37/170 (21%), Positives = 68/170 (40%), Gaps = 11/170 (6%)

Query: 56  EVGYHRDLSRNTAVL-LYLPEEDAFWVAGSAAGRP--------NTAQLRKLLSHQEQVLH 106
           +VGY + +S   AVL L L   DAF    +   +P        +   +    +  E    
Sbjct: 223 DVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFE 282

Query: 107 KSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHAS 166
           ++ PK+     K  L  +  ++  +   +       L  R+WDV   +GE+ L   A   
Sbjct: 283 ENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGI 342

Query: 167 FKIHREHLMKLSWSTVWEFQERLSQSWALEDNSVLRNLQTSMKELTKKHW 216
            K+  + L K+ +  + +F  RL +    E+  +  ++ T   +   K W
Sbjct: 343 LKLFEDILTKMDFIHMAQFLTRLPEDLPAEE--LFASIATIQMQSRNKKW 390


>gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens]
          Length = 693

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 37/170 (21%), Positives = 68/170 (40%), Gaps = 11/170 (6%)

Query: 56  EVGYHRDLSRNTAVL-LYLPEEDAFWVAGSAAGRP--------NTAQLRKLLSHQEQVLH 106
           +VGY + +S   AVL L L   DAF    +   +P        +   +    +  E    
Sbjct: 503 DVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFE 562

Query: 107 KSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHAS 166
           ++ PK+     K  L  +  ++  +   +       L  R+WDV   +GE+ L   A   
Sbjct: 563 ENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGI 622

Query: 167 FKIHREHLMKLSWSTVWEFQERLSQSWALEDNSVLRNLQTSMKELTKKHW 216
            K+  + L K+ +  + +F  RL +    E+  +  ++ T   +   K W
Sbjct: 623 LKLFEDILTKMDFIHMAQFLTRLPEDLPAEE--LFASIATIQMQSRNKKW 670


>gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens]
          Length = 693

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 37/170 (21%), Positives = 68/170 (40%), Gaps = 11/170 (6%)

Query: 56  EVGYHRDLSRNTAVL-LYLPEEDAFWVAGSAAGRP--------NTAQLRKLLSHQEQVLH 106
           +VGY + +S   AVL L L   DAF    +   +P        +   +    +  E    
Sbjct: 503 DVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFE 562

Query: 107 KSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHAS 166
           ++ PK+     K  L  +  ++  +   +       L  R+WDV   +GE+ L   A   
Sbjct: 563 ENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGI 622

Query: 167 FKIHREHLMKLSWSTVWEFQERLSQSWALEDNSVLRNLQTSMKELTKKHW 216
            K+  + L K+ +  + +F  RL +    E+  +  ++ T   +   K W
Sbjct: 623 LKLFEDILTKMDFIHMAQFLTRLPEDLPAEE--LFASIATIQMQSRNKKW 670


>gi|239756790 PREDICTED: similar to hCG1991532 [Homo sapiens]
          Length = 167

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 21/49 (42%), Positives = 31/49 (63%), Gaps = 1/49 (2%)

Query: 175 MKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPE 222
           MK S S +W  FQ++  Q+WAL+ ++VLR+LQ S+    K+    P PE
Sbjct: 1   MKASRSGLWARFQDQFPQTWALDSDAVLRHLQASVLSKPKQGSSAPRPE 49


>gi|29648315 small G protein signaling modulator 3 [Homo sapiens]
          Length = 749

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 9/130 (6%)

Query: 56  EVGYHRDLSRNTA-VLLYLPEEDAFWVAGSAAGR--PNTAQLRKLLSHQ--EQVLHKSFP 110
           E+GY +      A +LL+L EEDAFW+  +      P +     LL  Q  ++VL     
Sbjct: 197 EIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIV 256

Query: 111 KIMRQLGK--EGLCIEGSMLTR--LLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHAS 166
           + + +L K  +   IE S++T    L  F       L LR+WD+   EG +VL  +    
Sbjct: 257 QYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGM 316

Query: 167 FKIHREHLMK 176
             +  E L++
Sbjct: 317 LHLKEEELIQ 326


>gi|222352143 TBC1 domain family, member 2 [Homo sapiens]
          Length = 917

 Score = 38.1 bits (87), Expect = 0.011
 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 10/109 (9%)

Query: 57  VGYHRDLSRNTAVLLYLPEED--AFW--VAGSAAGRPNTAQLRKLLSHQ------EQVLH 106
           +GY + L+R  A+ L + EE+  AFW  VA      P       L + Q      + +L 
Sbjct: 709 IGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLS 768

Query: 107 KSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEG 155
           +  P++M  LG+  + +        L  F D     + LR+WD  + EG
Sbjct: 769 EKLPRLMAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWDAFLYEG 817


>gi|148806902 TBC1 domain family, member 12 [Homo sapiens]
          Length = 775

 Score = 35.4 bits (80), Expect = 0.073
 Identities = 29/145 (20%), Positives = 61/145 (42%), Gaps = 9/145 (6%)

Query: 56  EVGYHRDLSRNTAVL-LYLPEEDAFWVAGSAAGRP--------NTAQLRKLLSHQEQVLH 106
           +VGY + +S   AVL L L E DAF    +   +P        + + + K  +  E    
Sbjct: 584 DVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFE 643

Query: 107 KSFPKIMRQLGKEGLCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHAS 166
           ++  K+        L  +  ++  +   +       L  R+WDV   +GE+ L       
Sbjct: 644 ENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGI 703

Query: 167 FKIHREHLMKLSWSTVWEFQERLSQ 191
            +++ + L+++ +  + +F  +L +
Sbjct: 704 LRLYEDILLQMDFIHIAQFLTKLPE 728


>gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]
          Length = 336

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 31/130 (23%), Positives = 65/130 (50%), Gaps = 11/130 (8%)

Query: 57  VGYHRDLSRNTAVLLYLP--EEDAFWVAGSAAGR--PN--TAQLRKLLSHQE---QVLHK 107
           VGY + ++     L+ +   EE++FW+  +  GR  P+  +  +  L + QE   +++  
Sbjct: 151 VGYCQGMNFIAGYLILITNNEEESFWLLDALVGRILPDYYSPAMLGLKTDQEVLGELVRA 210

Query: 108 SFPKIMRQLGKEGLCIEGSMLTRLLQC-FLDGKSFGLTLRLWDVLILEGEQVLTAMAHAS 166
             P +   + + G+ +   +++R   C F+D       LR+WD L  EG +++  +A   
Sbjct: 211 KLPAVGALMERLGV-LWTLLVSRWFICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTL 269

Query: 167 FKIHREHLMK 176
            K H+E +++
Sbjct: 270 IKQHQELILE 279


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,619,955
Number of Sequences: 37866
Number of extensions: 585709
Number of successful extensions: 1547
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1476
Number of HSP's gapped (non-prelim): 46
length of query: 339
length of database: 18,247,518
effective HSP length: 103
effective length of query: 236
effective length of database: 14,347,320
effective search space: 3385967520
effective search space used: 3385967520
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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