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Search of human proteins with 239745674
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens]
(1941 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens] 3922 0.0
gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens] 3922 0.0
gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens] 3922 0.0
gi|149944548 neurobeachin-like 2 [Homo sapiens] 107 1e-22
gi|148233596 LPS-responsive vesicle trafficking, beach and ancho... 105 4e-22
gi|31543297 neutral sphingomyelinase (N-SMase) activation associ... 104 7e-22
gi|221625547 neutral sphingomyelinase (N-SMase) activation assoc... 104 7e-22
gi|62422577 neurobeachin [Homo sapiens] 103 1e-21
gi|224451124 neurobeachin-like 1 isoform 3 [Homo sapiens] 102 4e-21
gi|149944613 neurobeachin-like 1 isoform 1 [Homo sapiens] 102 4e-21
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 100 1e-20
gi|154240744 neurobeachin-like 1 isoform 2 [Homo sapiens] 96 3e-19
gi|191252801 WDFY family member 4 [Homo sapiens] 90 2e-17
gi|54292123 lysosomal trafficking regulator [Homo sapiens] 69 4e-11
gi|89886480 zinedin isoform 2 [Homo sapiens] 62 4e-09
gi|89886477 zinedin isoform 1 [Homo sapiens] 62 4e-09
gi|26665869 WD repeat domain 51B [Homo sapiens] 61 1e-08
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 59 5e-08
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 59 5e-08
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 59 5e-08
gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens] 56 4e-07
gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens] 56 4e-07
gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens] 56 4e-07
gi|21071067 TBP-associated factor 5 [Homo sapiens] 52 6e-06
gi|38569484 kinesin family member 21A [Homo sapiens] 51 1e-05
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 49 4e-05
gi|16554629 WD repeat domain 5 [Homo sapiens] 49 6e-05
gi|16554627 WD repeat domain 5 [Homo sapiens] 49 6e-05
gi|166795264 AE binding protein 2 isoform b [Homo sapiens] 49 6e-05
gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens] 49 6e-05
>gi|239756689 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 1941
Score = 3922 bits (10170), Expect = 0.0
Identities = 1941/1941 (100%), Positives = 1941/1941 (100%)
Query: 1 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60
MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA
Sbjct: 1 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60
Query: 61 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120
RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG
Sbjct: 61 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120
Query: 121 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180
GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA
Sbjct: 121 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180
Query: 181 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240
LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF
Sbjct: 181 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240
Query: 241 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300
SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR
Sbjct: 241 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300
Query: 301 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360
LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF
Sbjct: 301 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360
Query: 361 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420
HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT
Sbjct: 361 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420
Query: 421 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480
RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM
Sbjct: 421 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480
Query: 481 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540
ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD
Sbjct: 481 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540
Query: 541 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600
LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP
Sbjct: 541 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600
Query: 601 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660
EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE
Sbjct: 601 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660
Query: 661 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720
QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL
Sbjct: 661 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720
Query: 721 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780
LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE
Sbjct: 721 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780
Query: 781 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840
MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG
Sbjct: 781 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840
Query: 841 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900
KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE
Sbjct: 841 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900
Query: 901 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960
LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK
Sbjct: 901 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960
Query: 961 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020
YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE
Sbjct: 961 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020
Query: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080
ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP
Sbjct: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080
Query: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140
ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG
Sbjct: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140
Query: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200
DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG
Sbjct: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200
Query: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260
DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP
Sbjct: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260
Query: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320
TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS
Sbjct: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320
Query: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380
YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL
Sbjct: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380
Query: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440
TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ
Sbjct: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440
Query: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500
QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII
Sbjct: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500
Query: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560
RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG
Sbjct: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560
Query: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620
SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY
Sbjct: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620
Query: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680
WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY
Sbjct: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680
Query: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740
GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV
Sbjct: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740
Query: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800
PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS
Sbjct: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800
Query: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK
Sbjct: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
Query: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920
PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA
Sbjct: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920
Query: 1921 LLPTKRHLLLGSDNGVIRLLA 1941
LLPTKRHLLLGSDNGVIRLLA
Sbjct: 1921 LLPTKRHLLLGSDNGVIRLLA 1941
>gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 2240
Score = 3922 bits (10170), Expect = 0.0
Identities = 1941/1941 (100%), Positives = 1941/1941 (100%)
Query: 1 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60
MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA
Sbjct: 300 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 359
Query: 61 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120
RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG
Sbjct: 360 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 419
Query: 121 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180
GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA
Sbjct: 420 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 479
Query: 181 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240
LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF
Sbjct: 480 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 539
Query: 241 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300
SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR
Sbjct: 540 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 599
Query: 301 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360
LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF
Sbjct: 600 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 659
Query: 361 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420
HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT
Sbjct: 660 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 719
Query: 421 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480
RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM
Sbjct: 720 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 779
Query: 481 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540
ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD
Sbjct: 780 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 839
Query: 541 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600
LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP
Sbjct: 840 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 899
Query: 601 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660
EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE
Sbjct: 900 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 959
Query: 661 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720
QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL
Sbjct: 960 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 1019
Query: 721 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780
LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE
Sbjct: 1020 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 1079
Query: 781 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840
MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG
Sbjct: 1080 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 1139
Query: 841 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900
KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE
Sbjct: 1140 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 1199
Query: 901 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960
LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK
Sbjct: 1200 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 1259
Query: 961 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020
YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE
Sbjct: 1260 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1319
Query: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080
ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP
Sbjct: 1320 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1379
Query: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140
ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG
Sbjct: 1380 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1439
Query: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200
DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG
Sbjct: 1440 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1499
Query: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260
DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP
Sbjct: 1500 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1559
Query: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320
TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS
Sbjct: 1560 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1619
Query: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380
YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL
Sbjct: 1620 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1679
Query: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440
TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ
Sbjct: 1680 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1739
Query: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500
QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII
Sbjct: 1740 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1799
Query: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560
RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG
Sbjct: 1800 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1859
Query: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620
SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY
Sbjct: 1860 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1919
Query: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680
WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY
Sbjct: 1920 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1979
Query: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740
GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV
Sbjct: 1980 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 2039
Query: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800
PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS
Sbjct: 2040 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 2099
Query: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK
Sbjct: 2100 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 2159
Query: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920
PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA
Sbjct: 2160 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 2219
Query: 1921 LLPTKRHLLLGSDNGVIRLLA 1941
LLPTKRHLLLGSDNGVIRLLA
Sbjct: 2220 LLPTKRHLLLGSDNGVIRLLA 2240
>gi|239745674 PREDICTED: WD repeat domain 81 [Homo sapiens]
Length = 1941
Score = 3922 bits (10170), Expect = 0.0
Identities = 1941/1941 (100%), Positives = 1941/1941 (100%)
Query: 1 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60
MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA
Sbjct: 1 MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPA 60
Query: 61 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120
RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG
Sbjct: 61 RWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLG 120
Query: 121 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180
GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA
Sbjct: 121 GGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQA 180
Query: 181 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240
LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF
Sbjct: 181 LQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQF 240
Query: 241 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300
SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR
Sbjct: 241 SLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELR 300
Query: 301 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360
LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF
Sbjct: 301 LDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNF 360
Query: 361 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420
HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT
Sbjct: 361 HYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMT 420
Query: 421 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480
RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM
Sbjct: 421 RQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASM 480
Query: 481 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540
ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD
Sbjct: 481 ERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRD 540
Query: 541 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600
LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP
Sbjct: 541 LHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAP 600
Query: 601 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660
EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE
Sbjct: 601 EPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLE 660
Query: 661 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720
QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL
Sbjct: 661 QATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRIL 720
Query: 721 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780
LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE
Sbjct: 721 LPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAE 780
Query: 781 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840
MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG
Sbjct: 781 MVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERG 840
Query: 841 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900
KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE
Sbjct: 841 KLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRE 900
Query: 901 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960
LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK
Sbjct: 901 LVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANK 960
Query: 961 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020
YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE
Sbjct: 961 YLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQE 1020
Query: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080
ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP
Sbjct: 1021 ESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLP 1080
Query: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140
ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG
Sbjct: 1081 ETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSG 1140
Query: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200
DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG
Sbjct: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200
Query: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260
DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP
Sbjct: 1201 DGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGP 1260
Query: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320
TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS
Sbjct: 1261 TRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYIS 1320
Query: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380
YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL
Sbjct: 1321 YLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFL 1380
Query: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440
TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ
Sbjct: 1381 TSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQ 1440
Query: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500
QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII
Sbjct: 1441 QDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDII 1500
Query: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560
RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG
Sbjct: 1501 RKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFG 1560
Query: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620
SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY
Sbjct: 1561 SVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAY 1620
Query: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680
WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY
Sbjct: 1621 WQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680
Query: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740
GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV
Sbjct: 1681 GDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRV 1740
Query: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800
PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS
Sbjct: 1741 PLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS 1800
Query: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK
Sbjct: 1801 VVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
Query: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920
PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA
Sbjct: 1861 PTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLA 1920
Query: 1921 LLPTKRHLLLGSDNGVIRLLA 1941
LLPTKRHLLLGSDNGVIRLLA
Sbjct: 1921 LLPTKRHLLLGSDNGVIRLLA 1941
>gi|149944548 neurobeachin-like 2 [Homo sapiens]
Length = 2754
Score = 107 bits (267), Expect = 1e-22
Identities = 97/310 (31%), Positives = 131/310 (42%), Gaps = 68/310 (21%)
Query: 342 QEELRS--LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH----- 393
QE LR+ L WV ISNF YLMQLN +AGR D + +PV PWV+ D+ +P
Sbjct: 2056 QEMLRASGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPTLDLSN 2115
Query: 394 -GRFRDLRKSKFRLNKGDKQLDFTYEMTRQAFVA--GGAGGGEPPHVPHHISDVLSDITY 450
FRDL K +N QL R+ + + AG + H H S+ + Y
Sbjct: 2116 PAVFRDLSKPIGVVNPKHAQL------VREKYESFEDPAGTIDKFHYGTHYSNAAGVMHY 2169
Query: 451 YVYKARRTPRSVL-------CGH-----VRAQWEPH-EYPASMERMQNWTPDECIPEFYT 497
+ T V C V A W+ E PA ++ E IPEF+
Sbjct: 2170 LIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQARLESPADVK--------ELIPEFFY 2221
Query: 498 DPSIFRS-----------IHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWID 546
P + + + D+ +P W SS ++F+ HR LES VS LH WID
Sbjct: 2222 FPDFLENQNGFDLGCLQLTNEKVGDVVLPPWASSPEDFIQQHRQALESEYVSAHLHEWID 2281
Query: 547 LTFGYKLQGKEAVKEKNVCL-----------HLVDAHTHLASYGVV--------QLFDQP 587
L FGYK +G A + NV H+ D A G++ QL +P
Sbjct: 2282 LIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVTDERERKALEGIISNFGQTPCQLLKEP 2341
Query: 588 HPQRLAGAPA 597
HP RL+ A
Sbjct: 2342 HPTRLSAEEA 2351
Score = 32.7 bits (73), Expect = 3.5
Identities = 57/236 (24%), Positives = 84/236 (35%), Gaps = 38/236 (16%)
Query: 1580 GPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAYWQYEIGVSQQDAHFHFHQI 1639
GP P SGV G L D L SG +W + V+ Q+
Sbjct: 2452 GPWVPGSGVSGQALAVAPDGKLL----------FSGG---HWDGSLRVTALPRGKLLSQL 2498
Query: 1640 RLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYT--QHR 1697
H V C+A + + +SGS+D T +W L + G + AP+ V H
Sbjct: 2499 SC-----HLDVVTCLALDTCGIYLISGSRDTTCMVWRLLHQGGLSVGLAPKPVQVLYGHG 2553
Query: 1698 KSVFFVGQLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755
+V V VS DG V + G+ + + PL A P P +
Sbjct: 2554 AAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPLG--------ATFPGPIFHL 2605
Query: 1756 TMASSDS-TLRFVDCRKPGLQ-----HEFRLGGGLNPGLVRALAISPSGRSVVAGF 1805
+ S ++ +PG Q H + + G L L LA P+ +V F
Sbjct: 2606 ALGSEGQIVVQSSAWERPGAQVTYSLHLYSVNGKLRASL--PLAEQPTALTVTEDF 2659
>gi|148233596 LPS-responsive vesicle trafficking, beach and anchor
containing [Homo sapiens]
Length = 2863
Score = 105 bits (262), Expect = 4e-22
Identities = 93/287 (32%), Positives = 120/287 (41%), Gaps = 59/287 (20%)
Query: 352 WVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRDLRKSK 403
W H ISNF YLM LN +AGR D N +PV PWV+ D T P FRDL K
Sbjct: 2215 WQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPTN-FRDLSKPI 2273
Query: 404 FRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPH-HISDVLSDITYYV-YKARRTPRS 461
LN R AF A E VP H S ++ + + R P +
Sbjct: 2274 GALNP-----------KRAAFFAERYESWEDDQVPKFHYGTHYSTASFVLAWLLRIEPFT 2322
Query: 462 VLCGHVRAQWEPHEYPASMERMQNW------TPD--ECIPEFYTDPSIFRSIH------- 506
+++ H + W T D E IPEFY P +F + +
Sbjct: 2323 TYFLNLQGGKFDHADRTFSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVM 2382
Query: 507 ---PDMPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563
+ D+++P W +S+EFV +R LES VS LH WIDL FGYK QG EAV+ N
Sbjct: 2383 DDGTVVSDVELPPWAKTSEEFVHINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALN 2442
Query: 564 VCLHLV-----------------DAHTHLASYGVV--QLFDQPHPQR 591
V +L + S+G QL +PHP R
Sbjct: 2443 VFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPR 2489
>gi|31543297 neutral sphingomyelinase (N-SMase) activation
associated factor isoform 1 [Homo sapiens]
Length = 917
Score = 104 bits (260), Expect = 7e-22
Identities = 87/286 (30%), Positives = 127/286 (44%), Gaps = 49/286 (17%)
Query: 347 SLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRD 398
S +L W G +SN+ YL+ LN LA R D + +PV PW++ D + P G FRD
Sbjct: 300 SYMLQWQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWIIHDYSSSELDLSNP-GTFRD 358
Query: 399 LRKSKFRLNKG--DKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKAR 456
L K LNK ++ L EM F+ G + P +V ++ + + + R
Sbjct: 359 LSKPVGALNKERLERLLTRYQEMPEPKFMYG-SHYSSPGYVLFYLVRIAPEYMLCLQNGR 417
Query: 457 RTPRSVLCGHVRAQWEPHEYPASMERMQNWTPDECIPEFYTDPSIF--RSIHPDM----- 509
+ + W+ A+ + E IPEFY D F S+ D+
Sbjct: 418 FDNADRMFNSIAETWKNCLDGATDFK-------ELIPEFYGDDVSFLVNSLKLDLGKRQG 470
Query: 510 ----PDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKNVC 565
D+++P W SS ++F+ + LES VS LH WIDL FGYK +G +AV NV
Sbjct: 471 GQMVDDVELPPWASSPEDFLQKSKDALESNYVSEHLHEWIDLIFGYKQKGSDAVGAHNVF 530
Query: 566 LHL-----VDAH------------THLASYGVV--QLFDQPHPQRL 592
L VD + T + +G QLF PHP+R+
Sbjct: 531 HPLTYEGGVDLNSIQDPDEKVAMLTQILEFGQTPKQLFVTPHPRRI 576
Score = 35.8 bits (81), Expect = 0.42
Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 14/154 (9%)
Query: 1714 SCDGAVHVWDPFTGKTLRT-------VEPLDSRVPLTAVAVMPAPHTSITMASSDSTLRF 1766
S D V VW + T + L+ V + ++ + A T + + + T+
Sbjct: 731 SWDSTVKVWSGVPAEMPGTKRHHFDLLAELEHDVSVDTIS-LNAASTLLVSGTKEGTVNI 789
Query: 1767 VDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPA 1826
D L H+ + G+V A SP R V++ + G + ++D +TG+++ +
Sbjct: 790 WDLTTATLMHQIPC----HSGIVCDTAFSPDSRHVLSTGTDGCLNVIDVQTGMLISSMTS 845
Query: 1827 HEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
E + +G+ ++S S L VW L K
Sbjct: 846 DEPQ--RCFVWDGNSVLSGSQSGELLVWDLLGAK 877
>gi|221625547 neutral sphingomyelinase (N-SMase) activation
associated factor isoform 2 [Homo sapiens]
Length = 948
Score = 104 bits (260), Expect = 7e-22
Identities = 87/286 (30%), Positives = 127/286 (44%), Gaps = 49/286 (17%)
Query: 347 SLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRD 398
S +L W G +SN+ YL+ LN LA R D + +PV PW++ D + P G FRD
Sbjct: 331 SYMLQWQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWIIHDYSSSELDLSNP-GTFRD 389
Query: 399 LRKSKFRLNKG--DKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKAR 456
L K LNK ++ L EM F+ G + P +V ++ + + + R
Sbjct: 390 LSKPVGALNKERLERLLTRYQEMPEPKFMYG-SHYSSPGYVLFYLVRIAPEYMLCLQNGR 448
Query: 457 RTPRSVLCGHVRAQWEPHEYPASMERMQNWTPDECIPEFYTDPSIF--RSIHPDM----- 509
+ + W+ A+ + E IPEFY D F S+ D+
Sbjct: 449 FDNADRMFNSIAETWKNCLDGATDFK-------ELIPEFYGDDVSFLVNSLKLDLGKRQG 501
Query: 510 ----PDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKNVC 565
D+++P W SS ++F+ + LES VS LH WIDL FGYK +G +AV NV
Sbjct: 502 GQMVDDVELPPWASSPEDFLQKSKDALESNYVSEHLHEWIDLIFGYKQKGSDAVGAHNVF 561
Query: 566 LHL-----VDAH------------THLASYGVV--QLFDQPHPQRL 592
L VD + T + +G QLF PHP+R+
Sbjct: 562 HPLTYEGGVDLNSIQDPDEKVAMLTQILEFGQTPKQLFVTPHPRRI 607
Score = 35.8 bits (81), Expect = 0.42
Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 14/154 (9%)
Query: 1714 SCDGAVHVWDPFTGKTLRT-------VEPLDSRVPLTAVAVMPAPHTSITMASSDSTLRF 1766
S D V VW + T + L+ V + ++ + A T + + + T+
Sbjct: 762 SWDSTVKVWSGVPAEMPGTKRHHFDLLAELEHDVSVDTIS-LNAASTLLVSGTKEGTVNI 820
Query: 1767 VDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPA 1826
D L H+ + G+V A SP R V++ + G + ++D +TG+++ +
Sbjct: 821 WDLTTATLMHQIPC----HSGIVCDTAFSPDSRHVLSTGTDGCLNVIDVQTGMLISSMTS 876
Query: 1827 HEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
E + +G+ ++S S L VW L K
Sbjct: 877 DEPQ--RCFVWDGNSVLSGSQSGELLVWDLLGAK 908
>gi|62422577 neurobeachin [Homo sapiens]
Length = 2946
Score = 103 bits (258), Expect = 1e-21
Identities = 96/299 (32%), Positives = 127/299 (42%), Gaps = 50/299 (16%)
Query: 352 WVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV--------DFTTPHGRFRDLRKSK 403
W ISNF YLM LN +AGR D N +PV PWV+ D T P G FRDL K
Sbjct: 2289 WQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLP-GNFRDLSKPI 2347
Query: 404 FRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVL 463
LN K+ F E + P H H S S +++ V T +
Sbjct: 2348 GALNP--KRAVFYAER----YETWEDDQSPPYHYNTHYSTATSTLSWLVRIEPFTTFFLN 2401
Query: 464 CGHVRAQWEPHEYPA---SMERMQNWTPD--ECIPEFYTDPSIF----------RSIHPD 508
+ + + S Q T D E IPEFY P +F R
Sbjct: 2402 ANDGKFDHPDRTFSSVARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNLGVREDEVV 2461
Query: 509 MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKNVCLHL 568
+ D+D+P W ++FV +R LES VS LH WIDL FGYK +G EAV+ NV +L
Sbjct: 2462 VNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYL 2521
Query: 569 -------VDAHT----------HLASYGVV--QLFDQPHPQRLAGAP-ALAPEPPLIPK 607
+D+ T + ++G QL +PHP R + P+ PL+ K
Sbjct: 2522 TYEGSVNLDSITDPVLREAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFK 2580
>gi|224451124 neurobeachin-like 1 isoform 3 [Homo sapiens]
Length = 2694
Score = 102 bits (254), Expect = 4e-21
Identities = 88/294 (29%), Positives = 127/294 (43%), Gaps = 48/294 (16%)
Query: 348 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 400
L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL
Sbjct: 2003 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 2062
Query: 401 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 459
K +N K K + YE G + H H S+ + Y + T
Sbjct: 2063 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 2117
Query: 460 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 508
+ R A + H PA+ + + + D E IPEF+ P + +
Sbjct: 2118 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 2177
Query: 509 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563
+ D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N
Sbjct: 2178 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 2237
Query: 564 VCLH-----------LVDAHTHLASYGVV--------QLFDQPHPQRLAGAPAL 598
V + L D A G++ QL +PHP RL+ A+
Sbjct: 2238 VFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAV 2291
>gi|149944613 neurobeachin-like 1 isoform 1 [Homo sapiens]
Length = 1404
Score = 102 bits (254), Expect = 4e-21
Identities = 88/294 (29%), Positives = 127/294 (43%), Gaps = 48/294 (16%)
Query: 348 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 400
L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL
Sbjct: 713 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 772
Query: 401 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 459
K +N K K + YE G + H H S+ + Y + T
Sbjct: 773 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 827
Query: 460 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 508
+ R A + H PA+ + + + D E IPEF+ P + +
Sbjct: 828 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 887
Query: 509 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563
+ D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N
Sbjct: 888 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 947
Query: 564 VCLH-----------LVDAHTHLASYGVV--------QLFDQPHPQRLAGAPAL 598
V + L D A G++ QL +PHP RL+ A+
Sbjct: 948 VFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAV 1001
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 100 bits (249), Expect = 1e-20
Identities = 97/301 (32%), Positives = 123/301 (40%), Gaps = 71/301 (23%)
Query: 346 RSLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWV--------VDFTTPHGRFR 397
+S+ W G ISNF YLM LN LAGR D +PV PW+ VD T P FR
Sbjct: 2692 KSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPK-TFR 2750
Query: 398 DLRKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPP--HVPHHISDVLSDITYYVYKA 455
+L K Q D ++ + GE P H H S + +Y V
Sbjct: 2751 NLAKPM------GAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLV--- 2801
Query: 456 RRTPRSVLC-----GH----------VRAQWEPHEYPASMERMQNWTPDECIPEFYTDPS 500
R P + + GH VR W Y AS M + E IPEF+ P
Sbjct: 2802 RMEPFTQIFLRLQGGHFDLADRMFHSVREAW----YSASKHNMAD--VKELIPEFFYLPE 2855
Query: 501 -IFRSIHPDMP---------DLDVPAWCSSS-QEFVAAHRALLESREVSRDLHHWIDLTF 549
+F S + D+ D+ +P W +EF+ HR LE VS LH WIDL F
Sbjct: 2856 FLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIF 2915
Query: 550 GYKLQGKEAVKEKNVCLHLV-----------DAHTHLASYGVV--------QLFDQPHPQ 590
GYK QG AV+ NV HL D A+ G + QLF +PHP
Sbjct: 2916 GYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPP 2975
Query: 591 R 591
+
Sbjct: 2976 K 2976
Score = 36.2 bits (82), Expect = 0.32
Identities = 30/102 (29%), Positives = 44/102 (43%), Gaps = 13/102 (12%)
Query: 1623 YEIGVSQQDAHFHFHQIRL-QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG 1681
+E+G S++ A + L Q+ GH+ V C + +SGS+DRT +W L
Sbjct: 3105 WEMGTSKEKAK----TVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLS 3160
Query: 1682 DGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGA-VHVW 1722
T HR V + E +VSC G +HVW
Sbjct: 3161 FLTQ-------LRGHRAPVSALCINELTGDIVSCAGTYIHVW 3195
>gi|154240744 neurobeachin-like 1 isoform 2 [Homo sapiens]
Length = 1335
Score = 95.9 bits (237), Expect = 3e-19
Identities = 76/241 (31%), Positives = 109/241 (45%), Gaps = 29/241 (12%)
Query: 348 LVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPH------GRFRDLR 400
L WV+ ISNF YL+Q+N +AGR D +PV PW++ D+T+ FRDL
Sbjct: 713 LTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLS 772
Query: 401 KSKFRLN-KGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTP 459
K +N K K + YE G + H H S+ + Y + T
Sbjct: 773 KPIGVVNEKNAKAMREKYENFEDPM-----GTIDKFHYGTHYSNSAGVMHYLIRVEPFTT 827
Query: 460 RSVLCGHVR---AQWEPHEYPASMERMQNWTPD--ECIPEFYTDPSIFRSIHPD------ 508
+ R A + H PA+ + + + D E IPEF+ P + +
Sbjct: 828 LHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQ 887
Query: 509 -----MPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKN 563
+ D+ +P W S+++F+ HR LES VS LH WIDL FGYK +G AV+ N
Sbjct: 888 ISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALN 947
Query: 564 V 564
V
Sbjct: 948 V 948
>gi|191252801 WDFY family member 4 [Homo sapiens]
Length = 3184
Score = 89.7 bits (221), Expect = 2e-17
Identities = 91/305 (29%), Positives = 120/305 (39%), Gaps = 64/305 (20%)
Query: 346 RSLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPHGR------FRD 398
R ++ W ISNF YLM LN AGR D +PV PWV+ D+T+ FRD
Sbjct: 2536 RIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLADYTSETLNLANPKIFRD 2595
Query: 399 LRKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRT 458
L K K +++L F Q F G+ H+ + S I Y R
Sbjct: 2596 LSKPMGAQTK-ERKLKFI-----QRFKEVEKTEGDMTVQCHYYTHYSSAIIVASYLVRMP 2649
Query: 459 P-RSVLCG--------------HVRAQWEPHEYPASMERMQNWTPDECIPEFYTDPSIFR 503
P C V++ WE AS E M + E PEF+ P
Sbjct: 2650 PFTQAFCALQGGSFDVADRMFHSVKSTWES----ASRENMSDVR--ELTPEFFYLPEFLT 2703
Query: 504 SIH----------PDMPDLDVPAWCSSS-QEFVAAHRALLESREVSRDLHHWIDLTFGYK 552
+ + + D+ +P W ++F++ HR LES VS +LHHWIDL FGYK
Sbjct: 2704 NCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDLIFGYK 2763
Query: 553 LQGKEAVKEKNV-----------CLHLVDAHTHLASYGVV--------QLFDQPHPQRLA 593
QG AV N+ + D G V QLF +PHP R A
Sbjct: 2764 QQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPHPARTA 2823
Query: 594 GAPAL 598
L
Sbjct: 2824 AGKPL 2828
Score = 35.4 bits (80), Expect = 0.55
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 8/83 (9%)
Query: 1642 QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVF 1701
Q+ GH+ AV C+A + +SGS+D T LW L + T A HR+ +
Sbjct: 2976 QALYGHTQAVTCLAASVTFSLLVSGSQDCTCILWDLDHLTHVTRLPA-------HREGIS 3028
Query: 1702 FVGQLEAPQHVVSCDGA-VHVWD 1723
+ + +VSC GA + +W+
Sbjct: 3029 AITISDVSGTIVSCAGAHLSLWN 3051
>gi|54292123 lysosomal trafficking regulator [Homo sapiens]
Length = 3801
Score = 68.9 bits (167), Expect = 4e-11
Identities = 83/311 (26%), Positives = 122/311 (39%), Gaps = 54/311 (17%)
Query: 352 WVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVV-DFTTPHGRFRDL----RKSK--- 403
W G+I+NF YL LN+ AGR D +PV P+++ D+ + DL SK
Sbjct: 3135 WYTGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILADYVSETLDLNDLLIYRNLSKPIA 3194
Query: 404 -FRLNKGDKQLDFTYEMTRQAFVAGGAGGGE-PPHVPHHISDVLSDI-TYYVYKARRTPR 460
K D+ +D TY+ + + G PP P+H S+ T + R P
Sbjct: 3195 VQYKEKEDRYVD-TYKYLEEEYRKGAREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPF 3253
Query: 461 SVLCGHVRAQWEPHEYPASMERMQNWT-----------PDECIPEFYTDPSIF------- 502
+ + + Q + + P N T E IPEF+ P
Sbjct: 3254 TKM--FLAYQDQSFDIPDRTFHSTNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFD 3311
Query: 503 ---RSIHPDMPDLDVPAWCSSSQE-FVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEA 558
R + +++P W + F+ HR LES VS+++ WIDL FGYK +GK +
Sbjct: 3312 FGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESDYVSQNICQWIDLVFGYKQKGKAS 3371
Query: 559 VKEKNVC----------------LHLVDAHTHLASYGVV--QLFDQPHPQRLAGAPALAP 600
V+ NV + T + +YG QLF H R +
Sbjct: 3372 VQAINVFHPATYFGMDVSAVEDPVQRRALETMIKTYGQTPRQLFHMAHVSRPGAKLNIEG 3431
Query: 601 EPPLIPKLLVQ 611
E P LLVQ
Sbjct: 3432 ELPAAVGLLVQ 3442
>gi|89886480 zinedin isoform 2 [Homo sapiens]
Length = 760
Score = 62.4 bits (150), Expect = 4e-09
Identities = 65/260 (25%), Positives = 102/260 (39%), Gaps = 21/260 (8%)
Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG----DGTSETAPRLVYTQH 1696
+ +F H G V VA S+ ++ SG D + W + + DG + V H
Sbjct: 491 IHAFRAHRGPVLAVAMGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGH 550
Query: 1697 RKSVFFVGQLEAPQHVVSC--DGAVHVWDPFTGK-----TLRTVEPLDSRVPLTAVAVMP 1749
+V+ + Q + SC DG V +WDP + T T + + P
Sbjct: 551 GDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAFTSTEP 610
Query: 1750 APHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGF 1809
A H + S D+ L ++ L E R G P + + P+ +
Sbjct: 611 A-HIVASFRSGDTVLYDMEVGSALLTLESR--GSSGPTQINQVVSHPNQPLTITAHDDRG 667
Query: 1810 MVLLDTRTGLVLRGWPAHEGDILQIKAVE--GSVLVSSSSDHSLTVW----KELEQKPTH 1863
+ LD RTG + AH D + AV+ G+ L+S S D SL +W K Q+ T
Sbjct: 668 IRFLDNRTGKPVHSMVAHL-DAVTCLAVDPNGAFLMSGSHDCSLRLWSLDNKTCVQEITA 726
Query: 1864 HYKSASDPIHTFDLYGSEVV 1883
H K + IH + S+ +
Sbjct: 727 HRKKHEEAIHAVACHPSKAL 746
>gi|89886477 zinedin isoform 1 [Homo sapiens]
Length = 753
Score = 62.4 bits (150), Expect = 4e-09
Identities = 65/260 (25%), Positives = 102/260 (39%), Gaps = 21/260 (8%)
Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYG----DGTSETAPRLVYTQH 1696
+ +F H G V VA S+ ++ SG D + W + + DG + V H
Sbjct: 484 IHAFRAHRGPVLAVAMGSNSEYCYSGGADACIHSWKIPDLSMDPYDGYDPSVLSHVLEGH 543
Query: 1697 RKSVFFVGQLEAPQHVVSC--DGAVHVWDPFTGK-----TLRTVEPLDSRVPLTAVAVMP 1749
+V+ + Q + SC DG V +WDP + T T + + P
Sbjct: 544 GDAVWGLAFSPTSQRLASCSADGTVRIWDPSSSSPACLCTFPTASEHGVPTSVAFTSTEP 603
Query: 1750 APHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGF 1809
A H + S D+ L ++ L E R G P + + P+ +
Sbjct: 604 A-HIVASFRSGDTVLYDMEVGSALLTLESR--GSSGPTQINQVVSHPNQPLTITAHDDRG 660
Query: 1810 MVLLDTRTGLVLRGWPAHEGDILQIKAVE--GSVLVSSSSDHSLTVW----KELEQKPTH 1863
+ LD RTG + AH D + AV+ G+ L+S S D SL +W K Q+ T
Sbjct: 661 IRFLDNRTGKPVHSMVAHL-DAVTCLAVDPNGAFLMSGSHDCSLRLWSLDNKTCVQEITA 719
Query: 1864 HYKSASDPIHTFDLYGSEVV 1883
H K + IH + S+ +
Sbjct: 720 HRKKHEEAIHAVACHPSKAL 739
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 60.8 bits (146), Expect = 1e-08
Identities = 71/309 (22%), Positives = 122/309 (39%), Gaps = 42/309 (13%)
Query: 1640 RLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKS 1699
+ F H+ V+ V + F + S+D+++++W +Y R +Y+ +R +
Sbjct: 94 KFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQ---------RFLYSLYRHT 144
Query: 1700 VFFVGQLEAPQH--VVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755
+ +P +VSC D + +WD T K + V V T I
Sbjct: 145 HWVRCAKFSPDGRLIVSCSEDKTIKIWDT-TNK--QCVNNFSDSVGFANFVDFNPSGTCI 201
Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815
A SD T++ D R L +++ + G V ++ PSG ++ S G + +LD
Sbjct: 202 ASAGSDQTVKVWDVRVNKLLQHYQV----HSGGVNCISFHPSGNYLITASSDGTLKILDL 257
Query: 1816 RTGLVLRGWPAHEGDILQIKAVEGSVL-VSSSSDHSLTVWK----ELEQK-------PTH 1863
G ++ H G + + +G L S +D + +W+ EL K
Sbjct: 258 LEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDELHCKGLTKRNLKRL 317
Query: 1864 HYKSASDPIHTFDLY-------GSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTL 1916
H+ S P H D+Y +V T ++ K+ V L LS ++ T
Sbjct: 318 HFDS---PPHLLDIYPRTPHPHEEKVETVEINPKLEVIDLQISTPPVMDILSFDSTTTTE 374
Query: 1917 TSLALLPTK 1925
TS LP K
Sbjct: 375 TSGRTLPDK 383
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 58.9 bits (141), Expect = 5e-08
Identities = 61/224 (27%), Positives = 88/224 (39%), Gaps = 17/224 (7%)
Query: 1638 QIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHR 1697
Q R F GH AV CV S SGS+D+TVR+W G+ T V+ H
Sbjct: 13 QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST-------VFRAHT 65
Query: 1698 KSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755
+V V Q V S D V VW K L + L + A I
Sbjct: 66 ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFS---LSQHINWVRCAKFSPDGRLI 122
Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815
AS D T++ D H + G G V + PSG + A + + D
Sbjct: 123 VSASDDKTVKLWDKSSRECVHSYCEHG----GFVTYVDFHPSGTCIAAAGMDNTVKVWDV 178
Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELE 1858
RT +L+ + H + + G+ L+++SSD +L + +E
Sbjct: 179 RTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLME 222
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 58.9 bits (141), Expect = 5e-08
Identities = 61/224 (27%), Positives = 88/224 (39%), Gaps = 17/224 (7%)
Query: 1638 QIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHR 1697
Q R F GH AV CV S SGS+D+TVR+W G+ T V+ H
Sbjct: 51 QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST-------VFRAHT 103
Query: 1698 KSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755
+V V Q V S D V VW K L + L + A I
Sbjct: 104 ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFS---LSQHINWVRCAKFSPDGRLI 160
Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815
AS D T++ D H + G G V + PSG + A + + D
Sbjct: 161 VSASDDKTVKLWDKSSRECVHSYCEHG----GFVTYVDFHPSGTCIAAAGMDNTVKVWDV 216
Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELE 1858
RT +L+ + H + + G+ L+++SSD +L + +E
Sbjct: 217 RTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLME 260
Score = 43.1 bits (100), Expect = 0.003
Identities = 57/266 (21%), Positives = 104/266 (39%), Gaps = 31/266 (11%)
Query: 1644 FPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVFFV 1703
F GH AV CV + SGS D + +W + + +T H+ +V V
Sbjct: 15 FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHM-------KPQSRAYRFTGHKDAVTCV 67
Query: 1704 GQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPH-----TSI 1755
H++ S D V +W P +S V A + + H S
Sbjct: 68 -NFSPSGHLLASGSRDKTVRIWVPNVKG--------ESTVFRAHTATVRSVHFCSDGQSF 118
Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815
AS D T++ + + F L +N VR SP GR +V+ + L D
Sbjct: 119 VTASDDKTVKVWATHRQ--KFLFSLSQHIN--WVRCAKFSPDGRLIVSASDDKTVKLWDK 174
Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELEQKPTHHYKSASDPIH- 1873
+ + + H G + + G+ + ++ D+++ VW + HY+ S ++
Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 234
Query: 1874 -TFDLYGSEVVTGTVSNKIGVCSLLE 1898
+F G+ ++T + + + + L+E
Sbjct: 235 LSFHPSGNYLITASSDSTLKILDLME 260
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 58.9 bits (141), Expect = 5e-08
Identities = 61/224 (27%), Positives = 88/224 (39%), Gaps = 17/224 (7%)
Query: 1638 QIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHR 1697
Q R F GH AV CV S SGS+D+TVR+W G+ T V+ H
Sbjct: 51 QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST-------VFRAHT 103
Query: 1698 KSVFFVGQLEAPQHVV--SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755
+V V Q V S D V VW K L + L + A I
Sbjct: 104 ATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFS---LSQHINWVRCAKFSPDGRLI 160
Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815
AS D T++ D H + G G V + PSG + A + + D
Sbjct: 161 VSASDDKTVKLWDKSSRECVHSYCEHG----GFVTYVDFHPSGTCIAAAGMDNTVKVWDV 216
Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELE 1858
RT +L+ + H + + G+ L+++SSD +L + +E
Sbjct: 217 RTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLME 260
Score = 43.1 bits (100), Expect = 0.003
Identities = 57/266 (21%), Positives = 104/266 (39%), Gaps = 31/266 (11%)
Query: 1644 FPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVFFV 1703
F GH AV CV + SGS D + +W + + +T H+ +V V
Sbjct: 15 FKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHM-------KPQSRAYRFTGHKDAVTCV 67
Query: 1704 GQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPH-----TSI 1755
H++ S D V +W P +S V A + + H S
Sbjct: 68 -NFSPSGHLLASGSRDKTVRIWVPNVKG--------ESTVFRAHTATVRSVHFCSDGQSF 118
Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815
AS D T++ + + F L +N VR SP GR +V+ + L D
Sbjct: 119 VTASDDKTVKVWATHRQ--KFLFSLSQHIN--WVRCAKFSPDGRLIVSASDDKTVKLWDK 174
Query: 1816 RTGLVLRGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVWKELEQKPTHHYKSASDPIH- 1873
+ + + H G + + G+ + ++ D+++ VW + HY+ S ++
Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNG 234
Query: 1874 -TFDLYGSEVVTGTVSNKIGVCSLLE 1898
+F G+ ++T + + + + L+E
Sbjct: 235 LSFHPSGNYLITASSDSTLKILDLME 260
>gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens]
Length = 919
Score = 55.8 bits (133), Expect = 4e-07
Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 14/223 (6%)
Query: 1639 IRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1698
+R + H G++ CVA +GS D+ V++ P + + T P L ++ H
Sbjct: 652 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPF--NAETCNATGPDLEFSMHDG 709
Query: 1699 SVFFVGQLEAPQH----VVSC---DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAP 1751
++ + +E P+ ++S D ++ D G+ L + + +A+
Sbjct: 710 TIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI----LALYTWS 765
Query: 1752 HTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMV 1811
I S D T+RF D R P V ++A+ PSGR + G +
Sbjct: 766 GWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCM 825
Query: 1812 LLDTRTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTV 1853
L D R G +++ + H D+ ++ G+ L++ S D + V
Sbjct: 826 LYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 868
>gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens]
Length = 927
Score = 55.8 bits (133), Expect = 4e-07
Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 14/223 (6%)
Query: 1639 IRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1698
+R + H G++ CVA +GS D+ V++ P + + T P L ++ H
Sbjct: 660 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPF--NAETCNATGPDLEFSMHDG 717
Query: 1699 SVFFVGQLEAPQH----VVSC---DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAP 1751
++ + +E P+ ++S D ++ D G+ L + + +A+
Sbjct: 718 TIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI----LALYTWS 773
Query: 1752 HTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMV 1811
I S D T+RF D R P V ++A+ PSGR + G +
Sbjct: 774 GWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCM 833
Query: 1812 LLDTRTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTV 1853
L D R G +++ + H D+ ++ G+ L++ S D + V
Sbjct: 834 LYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 876
>gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens]
Length = 920
Score = 55.8 bits (133), Expect = 4e-07
Identities = 50/223 (22%), Positives = 93/223 (41%), Gaps = 14/223 (6%)
Query: 1639 IRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1698
+R + H G++ CVA +GS D+ V++ P + + T P L ++ H
Sbjct: 653 VRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPF--NAETCNATGPDLEFSMHDG 710
Query: 1699 SVFFVGQLEAPQH----VVSC---DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAP 1751
++ + +E P+ ++S D ++ D G+ L + + +A+
Sbjct: 711 TIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI----LALYTWS 766
Query: 1752 HTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMV 1811
I S D T+RF D R P V ++A+ PSGR + G +
Sbjct: 767 GWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCM 826
Query: 1812 LLDTRTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTV 1853
L D R G +++ + H D+ ++ G+ L++ S D + V
Sbjct: 827 LYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKV 869
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 52.0 bits (123), Expect = 6e-06
Identities = 64/253 (25%), Positives = 107/253 (42%), Gaps = 25/253 (9%)
Query: 1646 GHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLV-YTQHRKSVFFVG 1704
GHSG V + ++ LS S+D TVRLW L +T LV Y H V+
Sbjct: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSL--------QTFTCLVGYKGHNYPVWDTQ 592
Query: 1705 QLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTS-ITMASSD 1761
+ VS D +W + LR + V T P+++ + S+D
Sbjct: 593 FSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFH----PNSNYVATGSAD 648
Query: 1762 STLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTGLVL 1821
T+R D F + G + +L SP+GR + G + G ++L D GL++
Sbjct: 649 RTVRLWDVLNGNCVRIFTG----HKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMV 704
Query: 1822 RGWPAHEGDILQIK-AVEGSVLVSSSSDHSLTVW---KELEQKPTHHYKSASDPIHTFDL 1877
H + ++ + +G +L S S D+++ +W K E T + +A+ I+ +
Sbjct: 705 GELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAFEDLETDDFTTATGHINLPE- 763
Query: 1878 YGSEVVTGTVSNK 1890
E++ GT K
Sbjct: 764 NSQELLLGTYMTK 776
Score = 36.6 bits (83), Expect = 0.25
Identities = 17/45 (37%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 1635 HFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYN 1679
H+ +R+ F GH V C + ++ +GS DRTVRLW + N
Sbjct: 616 HYQPLRI--FAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 51.2 bits (121), Expect = 1e-05
Identities = 56/236 (23%), Positives = 95/236 (40%), Gaps = 28/236 (11%)
Query: 1646 GHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGD-----GTSETAPRLVYTQHRKSV 1700
GH+ AV CV S++D +GSKDRT ++W L + G + Y + V
Sbjct: 1332 GHTKAVLCVD--STDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLV 1389
Query: 1701 FFVGQLEAPQ----------HVVSCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPA 1750
F V ++ G V + D + T RTV + +A+ P
Sbjct: 1390 FTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQINQIALNPT 1449
Query: 1751 PHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRS-VVAGFSSGF 1809
+ A+S + +R D ++ Q +L G L P + + SG+ ++ G +
Sbjct: 1450 --GTFLYAASGNAVRMWDLKR--FQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDHY 1505
Query: 1810 MVLLDTRTGLVLRGWPAH-----EGDILQIKAVEGSVLVSSSSDHSLTVWKELEQK 1860
+ + D G + P H D ++ ++G L S S D+ + W +L QK
Sbjct: 1506 IKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKW-DLTQK 1560
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 49.3 bits (116), Expect = 4e-05
Identities = 52/220 (23%), Positives = 91/220 (41%), Gaps = 20/220 (9%)
Query: 1640 RLQSFPGHSGAVKC-VAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRK 1698
+LQ H+ V V +S +G D V LW + S T +T +
Sbjct: 12 KLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTG----HTSPVE 67
Query: 1699 SVFFVGQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSI 1755
SV +L P+ ++ S G++ VWD K LRT+ + + + ++ P +
Sbjct: 68 SV----RLNTPEELIVAGSQSGSIRVWDLEAAKILRTL--MGHKANICSLDFHPYGEF-V 120
Query: 1756 TMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDT 1815
S D+ ++ D R+ G +R + VR L SP G+ + + + L D
Sbjct: 121 ASGSQDTNIKLWDIRRKGCVFRYRG----HSQAVRCLRFSPDGKWLASAADDHTVKLWDL 176
Query: 1816 RTGLVLRGWPAHEGDILQIKAVEGS-VLVSSSSDHSLTVW 1854
G ++ +P H G + ++ +L S SSD ++ W
Sbjct: 177 TAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFW 216
Score = 38.5 bits (88), Expect = 0.065
Identities = 17/40 (42%), Positives = 22/40 (55%)
Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNY 1680
+ FPGH+G V V +E SGS DRT+R W L +
Sbjct: 182 MSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKF 221
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 48.5 bits (114), Expect = 6e-05
Identities = 57/239 (23%), Positives = 98/239 (41%), Gaps = 35/239 (14%)
Query: 1642 QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVF 1701
++ GH + VA S + +S S D+T+++W + + L + +
Sbjct: 81 KTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV--------SSGKCLKTLKGHSNYV 132
Query: 1702 FVGQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 1758
F +++ S D +V +WD TGK L+T+ P S P++AV + I +
Sbjct: 133 FCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL-PAHSD-PVSAVH-FNRDGSLIVSS 189
Query: 1759 SSDSTLRFVD-----CRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLL 1813
S D R D C K + + NP V + SP+G+ ++A + L
Sbjct: 190 SYDGLCRIWDTASGQCLKTLIDDD-------NPP-VSFVKFSPNGKYILAATLDNTLKLW 241
Query: 1814 DTRTGLVLRGWPAHEGD----ILQIKAVEGSVLVSSSSDHSLTVW----KELEQKPTHH 1864
D G L+ + H+ + G +VS S D+ + +W KE+ QK H
Sbjct: 242 DYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH 300
Score = 40.0 bits (92), Expect = 0.022
Identities = 50/220 (22%), Positives = 91/220 (41%), Gaps = 15/220 (6%)
Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSV 1700
L++ GHS V C + +SGS D +VR+W + +T P H V
Sbjct: 122 LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT--GKCLKTLP-----AHSDPV 174
Query: 1701 FFVGQLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 1758
V +VS DG +WD +G+ L+T+ D P++ V P I A
Sbjct: 175 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID-DDNPPVSFVKFSP-NGKYILAA 232
Query: 1759 SSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTG 1818
+ D+TL+ D K G + G + A G+ +V+G + + + +T
Sbjct: 233 TLDNTLKLWDYSK-GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTK 291
Query: 1819 LVLRGWPAHEGDILQIKAVEGSVLVSSS---SDHSLTVWK 1855
+++ H ++ +++S+ +D ++ +WK
Sbjct: 292 EIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 48.5 bits (114), Expect = 6e-05
Identities = 57/239 (23%), Positives = 98/239 (41%), Gaps = 35/239 (14%)
Query: 1642 QSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVF 1701
++ GH + VA S + +S S D+T+++W + + L + +
Sbjct: 81 KTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV--------SSGKCLKTLKGHSNYV 132
Query: 1702 FVGQLEAPQHVV---SCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 1758
F +++ S D +V +WD TGK L+T+ P S P++AV + I +
Sbjct: 133 FCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL-PAHSD-PVSAVH-FNRDGSLIVSS 189
Query: 1759 SSDSTLRFVD-----CRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLL 1813
S D R D C K + + NP V + SP+G+ ++A + L
Sbjct: 190 SYDGLCRIWDTASGQCLKTLIDDD-------NPP-VSFVKFSPNGKYILAATLDNTLKLW 241
Query: 1814 DTRTGLVLRGWPAHEGD----ILQIKAVEGSVLVSSSSDHSLTVW----KELEQKPTHH 1864
D G L+ + H+ + G +VS S D+ + +W KE+ QK H
Sbjct: 242 DYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH 300
Score = 40.0 bits (92), Expect = 0.022
Identities = 50/220 (22%), Positives = 91/220 (41%), Gaps = 15/220 (6%)
Query: 1641 LQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSV 1700
L++ GHS V C + +SGS D +VR+W + +T P H V
Sbjct: 122 LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKT--GKCLKTLP-----AHSDPV 174
Query: 1701 FFVGQLEAPQHVVSC--DGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMA 1758
V +VS DG +WD +G+ L+T+ D P++ V P I A
Sbjct: 175 SAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID-DDNPPVSFVKFSP-NGKYILAA 232
Query: 1759 SSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTG 1818
+ D+TL+ D K G + G + A G+ +V+G + + + +T
Sbjct: 233 TLDNTLKLWDYSK-GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTK 291
Query: 1819 LVLRGWPAHEGDILQIKAVEGSVLVSSS---SDHSLTVWK 1855
+++ H ++ +++S+ +D ++ +WK
Sbjct: 292 EIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331
>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
Length = 517
Score = 48.5 bits (114), Expect = 6e-05
Identities = 44/146 (30%), Positives = 64/146 (43%), Gaps = 12/146 (8%)
Query: 1064 LPDYTSGVSFHDQADLPETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEER 1123
LP + G + +A+ PE E+ + E + EAEAV+ L+ S G
Sbjct: 20 LPPGSPGSAARGRAEPPEEEEEEE-----EEEEEAEAEAVAALLLNGGSGGG----GGGG 70
Query: 1124 APDEGGAPVDKSSLRSGDSSQDLKQSEGSEE---EEEEEDSCVVLEEEEGEQEEVTGASE 1180
GG + S S +S+ + E EE EEE+E S EEE E + G+S
Sbjct: 71 GGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSG 130
Query: 1181 LTLSDTVLSMETVVAGGSGGDGEEEE 1206
+ SD S+ A S GDG+ +E
Sbjct: 131 GSSSDETRSLSPGAASSSSGDGDGKE 156
>gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]
Length = 234
Score = 48.5 bits (114), Expect = 6e-05
Identities = 31/81 (38%), Positives = 43/81 (53%), Gaps = 6/81 (7%)
Query: 1141 DSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGG 1200
D + L E E EEE ++ V+E+EEGE+EE G E D E G + G
Sbjct: 158 DHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEE----DVSGGDEEDEEGYNDG 213
Query: 1201 --DGEEEEEALPEQSEGKEQK 1219
DGEE+EE L E+ G+++K
Sbjct: 214 EVDGEEDEEELGEEERGQKRK 234
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,716,414
Number of Sequences: 37866
Number of extensions: 4590288
Number of successful extensions: 26994
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 151
Number of HSP's successfully gapped in prelim test: 369
Number of HSP's that attempted gapping in prelim test: 21144
Number of HSP's gapped (non-prelim): 3345
length of query: 1941
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1824
effective length of database: 13,817,196
effective search space: 25202565504
effective search space used: 25202565504
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.